The ISIS project: Fault-tolerance in large distributed systems

NASA Technical Reports Server (NTRS)

Birman, Kenneth P.; Marzullo, Keith

1990-01-01

The semi-annual status report covers activities of the ISIS project during the second half of 1989. The project had several independent objectives: (1) At the level of the ISIS Toolkit, ISIS release V2.0 was completed, containing bypass communication protocols. Performance of the system is greatly enhanced by this change, but the initial software release is limited in some respects. (2) The Meta project focused on the definition of the Lomita programming language for specifying rules that monitor sensors for conditions of interest and triggering appropriate reactions. This design was completed, and implementation of Lomita is underway on the Meta 2.0 platform. (3) The Deceit file system effort completed a prototype. It is planned to make Deceit available for use in two hospital information systems. (4) A long-haul communication subsystem project was completed and can be used as part of ISIS. This effort resulted in tools for linking ISIS systems on different LANs together over long-haul communications lines. (5) Magic Lantern, a graphical tool for building application monitoring and control interfaces, is included as part of the general ISIS releases.

Topside Ionogram Scaler With True Height Algorithm (TOPIST): Automated processing of ISIS topside ionograms

NASA Astrophysics Data System (ADS)

Bilitza, Dieter; Huang, Xueqin; Reinisch, Bodo W.; Benson, Robert F.; Hills, H. Kent; Schar, William B.

2004-02-01

The United States/Canadian ISIS-1 and ISIS-2 satellites collected several million topside ionograms in the 1960s and 1970s with a multinational network of ground stations that provided good global coverage. However, processing of these ionograms into electron density profiles required time-consuming manual scaling of the traces from the analog ionograms, and as a result, only a few percent of the ionograms had been processed into electron density profiles. In recent years an effort began to digitize the analog recordings to prepare the ionograms for computerized analysis. As of November 2002, approximately 390,000 ISIS-1 and ISIS-2 digital topside-sounder ionograms have been produced. The Topside Ionogram Scaler With True Height Algorithm (TOPIST) program was developed for the automated scaling of the echo traces and for the inversion of these traces into topside electron density profiles. The program is based on the techniques that have been successfully applied in the analysis of ground-based Digisonde ionograms. The TOPIST software also includes an "editing option" for manual scaling of the more difficult ionograms, which could not be scaled during the automated TOPIST run. TOPIST is now successfully scaling ˜60% of the ISIS ionograms, and the electron density profiles are available through the online archive of the National Space Science Data Center at ftp://nssdcftp.gsfc.nasa.gov/spacecraft_data/isis/topside_sounder. This data restoration effort is producing a unique global database of topside electron densities over more than one solar cycle, which will be of particular importance for improvements of topside ionosphere models, especially the International Reference Ionosphere.

76 FR 35219 - Submission for OMB Review; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-16

... service environment in which the evaluation is implemented and the opportunities for control group members to access the same or similar services as the treatment group members. Respondents: Individuals enrolled in ISIS demonstration interventions, control group members, ISIS program operators (BIF and SAQ...

Leveraging ISI Multi-Model Prediction for Navy Operations: Proposal to the Office of Naval Research

DTIC Science & Technology

2014-09-30

ISI Multi-Model Prediction for Navy Operations: Proposal to the Office of Naval Research PI: James L. Kinter III Director, Center for Ocean-Land...TYPE 3. DATES COVERED 00-00-2014 to 00-00-2014 4. TITLE AND SUBTITLE Leveraging ISI Multi-Model Prediction for Navy Operations: Proposal to the ... Office of Naval Research 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f

Teachers' implementation of reform-oriented instructional strategies in science: Lessons from two professional development programs

NASA Astrophysics Data System (ADS)

Cook, Nicole D.

This dissertation reports findings from two studies that investigated the relationship between professional development and teachers' instructional practices in Science,Technology, Engineering, and Mathematics (STEM). The first program, the Indiana Science Initiative (ISI) focused on K-8 teachers and their use of inquiry-based science instruction in conjunction with curricular modules provided by the ISI program. The second program, Research Goes to School (RGS), focused on high school STEM teachers and their use of problem-based learning (PBL) as they implemented curricular units that they developed themselves at the RGS summer workshop. In-service teachers were recruited from both programs. They were observed teaching their respective curricular materials and interviewed about their experiences in order to investigate the following research questions: 1. How do teachers implement the reform-oriented instructional strategies promoted by their professional development experiences with the ISI or RGS? 2. What are the challenges and supports that influence teachers' use of the reform-oriented instructional strategies promoted by their professional development experiences with the ISI or RGS? To investigate these questions the fidelity of implementation was it was conceptualized by Century, Rudnick, and Freeman (2010) was used as a theoretical framework. The study of the ISI program was conducted during the program's pilot year (2010-11). Five teachers of grades 3 through 6 were recruited from three different schools. Participants were observed as they taught lessons related to the modules and they were interviewed about their experiences. Based on analysis of the data from the observations, using a modified version of the Science Teacher Inquiry Rubric (STIR) (Bodzin & Beerer, 2003), the participants were found to exhibit partial fidelity of implementation to the model of inquiry-based instruction promoted by the ISI. Based on data from the interviews, the participants in this study perceived time for science instruction, limits in their students' abilities and behavior, and their own development as facilitators as challenges to their efforts to implement inquiry-based science instruction. They identified their participation in the ISI pilot, the curricular modules and a science notebook strategy promoted by the ISI as supports for their instruction. Two studies of the RGS program were conducted. The first was a pilot study that was conducted in the academic year following the first RGS summer workshop (2011-12). The second was a collective case study conducted after the second RGS workshop (2012-13). In both studies participants were videotaped as they implemented the PBL units that they had developed at their respective RGS workshops and interviewed about their experiences after they implemented the units. The data from the observations were examined using a rubric developed for the study to examine their use of PBL features. Based on the analysis of the data from the observations, the RGS participants exhibited partial fidelity of implementation to the features of PBL. Analysis of the data from the interviews indicated that participants were aware of features of PBL that they were not able to fully implement. Participants also identified several supports, particularly from the RGS program such as being able to order materials to implement their units, as well as supports that were specific to their teaching contexts. The findings from both the ISI study and RGS collective case study suggest that the professional development programs had some positive if limited influence on teachers' instructional practices. Across the studies, persistent challenges were identified regarding teachers' efforts to meaningfully engage students in practices that would develop their abilities to reason scientifically. Comments from participants in both studies about the supportive role of their respective curricula also lend support to arguments about the role of curriculum materials in achieving science education reform (Powell & Anderson, 2002).

Steam generator tubing NDE performance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Henry, G.; Welty, C.S. Jr.

1997-02-01

Steam generator (SG) non-destructive examination (NDE) is a fundamental element in the broader SG in-service inspection (ISI) process, a cornerstone in the management of PWR steam generators. Based on objective performance measures (tube leak forced outages and SG-related capacity factor loss), ISI performance has shown a continually improving trend over the years. Performance of the NDE element is a function of the fundamental capability of the technique, and the ability of the analysis portion of the process in field implementation of the technique. The technology continues to improve in several areas, e.g. system sensitivity, data collection rates, probe/coil design, andmore » data analysis software. With these improvements comes the attendant requirement for qualification of the technique on the damage form(s) to which it will be applied, and for training and qualification of the data analysis element of the ISI process on the field implementation of the technique. The introduction of data transfer via fiber optic line allows for remote data acquisition and analysis, thus improving the efficiency of analysis for a limited pool of data analysts. This paper provides an overview of the current status of SG NDE, and identifies several important issues to be addressed.« less

Unesco Integrated Documentation Network; Computerized Documentation System (CDS).

ERIC Educational Resources Information Center

United Nations Educational, Scientific, and Cultural Organization, Paris (France). Dept. of Documentation, Libraries, and Archives.

Intended for use by the Computerized Documentation System (CDS), the Unesco version of ISIS (Integrated Set of Information Systems)--originally developed by the International Labour Organization--was developed in 1975 and named CDS/ISIS. This system has a comprehensive collection of programs for input, management, and output, running in batch or…

Design alternatives for process group membership and multicast

NASA Technical Reports Server (NTRS)

Birman, Kenneth P.; Cooper, Robert; Gleeson, Barry

1991-01-01

Process groups are a natural tool for distributed programming, and are increasingly important in distributed computing environments. However, there is little agreement on the most appropriate semantics for process group membership and group communication. These issues are of special importance in the Isis system, a toolkit for distributed programming. Isis supports several styles of process group, and a collection of group communication protocols spanning a range of atomicity and ordering properties. This flexibility makes Isis adaptable to a variety of applications, but is also a source of complexity that limits performance. This paper reports on a new architecture that arose from an effort to simplify Isis process group semantics. Our findings include a refined notion of how the clients of a group should be treated, what the properties of a multicast primitive should be when systems contain large numbers of overlapping groups, and a new construct called the casuality domain. As an illustration, we apply the architecture to the problem of converting processes into fault-tolerant process groups in a manner that is 'transparent' to other processes in the system.

Are the Insomnia Severity Index and Pittsburgh Sleep Quality Index valid outcome measures for Cognitive Behavioral Therapy for Insomnia? Inquiry from the perspective of response shifts and longitudinal measurement invariance in their Chinese versions.

PubMed

Chen, Po-Yi; Jan, Ya-Wen; Yang, Chien-Ming

2017-07-01

The purpose of this study was to examine whether the Insomnia Severity Index (ISI) and Pittsburgh Sleep Quality Index (PSQI) are valid outcome measures for Cognitive Behavioral Therapy for Insomnia (CBT-I). Specifically, we tested whether the factorial parameters of the ISI and the PSQI could remain invariant against CBT-I, which is a prerequisite to using their change scores as an unbiased measure of the treatment outcome of CBT-I. A clinical data set including scores on the Chinese versions of the ISI and the PSQI obtained from 114 insomnia patients prior to and after a 6-week CBT-I program in Taiwan was analyzed. A series of measurement invariance (MI) tests were conducted to compare the factorial parameters of the ISI and the PSQI before and after the CBT-I treatment program. Most factorial parameters of the ISI remained invariant after CBT-I. However, the factorial model of the PSQI changed after CBT-I treatment. An extra loading with three residual correlations was added into the factorial model after treatment. The partial strong invariance of the ISI supports that it is a valid outcome measure for CBT-I. In contrast, various changes in the factor model of the PSQI indicate that it may not be an appropriate outcome measure for CBT-I. Some possible causes for the changes of the constructs of the PSQI following CBT-I are discussed. Copyright © 2017 Elsevier B.V. All rights reserved.

Alouette and ISIS topside sounder measurements -A data source for improvements of the IRI model in the topside ionosphere

NASA Astrophysics Data System (ADS)

Bilitza, Dieter; Benson, Robert; Reinisch, Bodo; Huang, Xueqin

The Alouette and ISIS topside sounder satellites recorded a great wealth of information about the topside ionosphere during their long period of operations (from 1962 to 1990). So much though that only a small percentage was analyzed during the mission life time. The soundings were stored on more than 100,000 seven-track analog telemetry tapes. In the mid-nineties space limitations and storage costs threatened an imminent loss of these tapes. Only a last minute intervention spear-headed by NASA's Ionosphere, Thermosphere, Mesosphere (ITM) Data Evaluation Panel saved a significant portion of these tapes and with funding from the AISRP program these data were first digitized and then converted into electron density profiles. This data restoration effort more than tripled the Alouette/ISIS topside sounder data base and has led to significant improvements of models for the topside ionosphere, e.g., about a factor of 2 improvement in the case of the IRI-2007 topside electron density profile. We will present a brief history of this successful data restoration effort and its current status. The homepage for the ISIS project is at http://nssdc.gsfc.nasa.gov/space/isis/isis-status.html.

Interim Service ISDN Satellite (ISIS) network model for advanced satellite designs and experiments

NASA Technical Reports Server (NTRS)

Pepin, Gerard R.; Hager, E. Paul

1991-01-01

The Interim Service Integrated Services Digital Network (ISDN) Satellite (ISIS) Network Model for Advanced Satellite Designs and Experiments describes a model suitable for discrete event simulations. A top-down model design uses the Advanced Communications Technology Satellite (ACTS) as its basis. The ISDN modeling abstractions are added to permit the determination and performance for the NASA Satellite Communications Research (SCAR) Program.

ISY Mission to Planet Earth Conference: A planning meeting for the International Space Year

NASA Technical Reports Server (NTRS)

Meyerson, Harvey

1991-01-01

A major theme was the opportunity offered by the International Space Year (ISY) to initiate a long-term program of Earth observation mission coordination and worldwide data standardization. The challenge is immense and extremely time critical. A recommendation was made to inventory the capabilities of Earth observing spacecraft scheduled during the next decade. The ISY effort to strengthen coordination and standardization should emphasize global issues, and also regional initiatives of particular relevance to developing nations. The concepts of a Global Information System Test (GIST) was accepted and applied to specific issues of immediate concern. The importance of ISY Earth observation initiatives extending beyond research to include immediate and direct applications for social and economic development was stressed. Several specific Mission to Planet Earth proposals were developed during the Conference. A mechanism was set up for coordinating participation of the national space agencies or equivalent bodies.

Interim Service ISDN Satellite (ISIS) simulator development for advanced satellite designs and experiments

NASA Technical Reports Server (NTRS)

Pepin, Gerard R.

1992-01-01

The simulation development associated with the network models of both the Interim Service Integrated Services Digital Network (ISDN) Satellite (ISIS) and the Full Service ISDN Satellite (FSIS) architectures is documented. The ISIS Network Model design represents satellite systems like the Advanced Communications Technology Satellite (ACTS) orbiting switch. The FSIS architecture, the ultimate aim of this element of the Satellite Communications Applications Research (SCAR) Program, moves all control and switching functions on-board the next generation ISDN communications satellite. The technical and operational parameters for the advanced ISDN communications satellite design will be obtained from the simulation of ISIS and FSIS engineering software models for their major subsystems. Discrete event simulation experiments will be performed with these models using various traffic scenarios, design parameters, and operational procedures. The data from these simulations will be used to determine the engineering parameters for the advanced ISDN communications satellite.

The ISIS Story - Science Return from Rescuing, Archiving and Analyzing a Unique Dataset

NASA Astrophysics Data System (ADS)

Bilitza, D.; Benson, R. F.; Reinisch, B. W.; Huang, X.

2009-12-01

The Alouette and ISIS topside sounder satellites recorded a great wealth of information about the topside ionosphere during their long periods of operation (from 1962 to 1990). Even though more than 700 publications resulted from this project, only a small percentage of the dataset was analyzed during the mission life time. The soundings were stored on more than 100,000 seven-track analog telemetry tapes. In the mid-nineties space limitations and storage costs threatened an imminent loss of these tapes. Only a last minute intervention spear-headed by NASA’s Ionosphere, Thermosphere, Mesosphere (ITM) Data Evaluation Panel saved a significant portion of these tapes and with funding from the AISRP program these data were first digitized and then converted into electron density profiles. This data restoration effort more than tripled the Alouette/ISIS topside sounder data base and has led to significant improvements of models for the topside ionosphere, e.g., about a factor of 2 improvement in the case of the IRI-2007 topside electron density profile. We will present a brief history of this successful data restoration effort and will highlight the science dividends this investment has produced. The homepage for the ISIS project is at http://nssdc.gsfc.nasa.gov/space/isis/isis-status.html.

ISIS and META projects

NASA Technical Reports Server (NTRS)

Birman, Kenneth; Cooper, Robert; Marzullo, Keith

1990-01-01

The ISIS project has developed a new methodology, virtual synchony, for writing robust distributed software. High performance multicast, large scale applications, and wide area networks are the focus of interest. Several interesting applications that exploit the strengths of ISIS, including an NFS-compatible replicated file system, are being developed. The META project is distributed control in a soft real-time environment incorporating feedback. This domain encompasses examples as diverse as monitoring inventory and consumption on a factory floor, and performing load-balancing on a distributed computing system. One of the first uses of META is for distributed application management: the tasks of configuring a distributed program, dynamically adapting to failures, and monitoring its performance. Recent progress and current plans are reported.

Identification and Characterization of the Iridoid Synthase Involved in Oleuropein Biosynthesis in Olive (Olea europaea) Fruits*

PubMed Central

Kries, Hajo; Panara, Francesco; Baldoni, Luciana; O'Connor, Sarah E.; Osbourn, Anne

2016-01-01

The secoiridoids are the main class of specialized metabolites present in olive (Olea europaea L.) fruit. In particular, the secoiridoid oleuropein strongly influences olive oil quality because of its bitterness, which is a desirable trait. In addition, oleuropein possesses a wide range of pharmacological properties, including antioxidant, anti-inflammatory, and anti-cancer activities. In accordance, obtaining high oleuropein varieties is a main goal of molecular breeding programs. Here we use a transcriptomic approach to identify candidate genes belonging to the secoiridoid pathway in olive. From these candidates, we have functionally characterized the olive homologue of iridoid synthase (OeISY), an unusual terpene cyclase that couples an NAD (P)H-dependent 1,4-reduction step with a subsequent cyclization, and we provide evidence that OeISY likely generates the monoterpene scaffold of oleuropein in olive fruits. OeISY, the first pathway gene characterized for this type of secoiridoid, is a potential target for breeding programs in a high value secoiridoid-accumulating species. PMID:26709230

Data Services Upgrade: Perfecting the ISIS-I Topside Digital Ionogram Database

NASA Technical Reports Server (NTRS)

Wang, Yongli; Benson, Robert F.; Bilitza, Dieter; Fung, Shing. F.; Chu, Philip; Huang, Xueqin; Truhlik, Vladimir

2015-01-01

The ionospheric topside sounders of the International Satellites for Ionospheric Studies (ISIS) program were designed as analog systems. More than 16,000 of the original telemetry tapes from three satellites were used to produce topside digital ionograms, via an analog-to-digital (A/D) conversion process, suitable for modern analysis techniques. Unfortunately, many of the resulting digital topside ionogram files could not be auto-processed to produce topside Ne(h) profiles because of problems encountered during the A/D process. Software has been written to resolve these problems and here we report on (1) the first application of this software to a significant portion of the ISIS-1 digital topside-ionogram database, (2) software improvements motivated by this activity, (3) N(sub e)(h) profiles automatically produced from these corrected ISIS-1 digital ionogram files, and (4) the availability via the Virtual Wave Observatory (VWO) of the corrected ISIS-1 digital topside ionogram files for research. We will also demonstrate the use of these N(sub e)(h) profiles for making refinements in the International Reference Ionosphere (IRI) and in the determination of transition heights from Oxygen ion to Hydrogen ion.

New satellite mission with old data: Rescuing a unique data set

NASA Astrophysics Data System (ADS)

Benson, Robert F.; Bilitza, Dieter

2009-02-01

We review efforts to save a unique data set and scientific results based on the rescued data. The goal of the project was to produce Alouette 2, ISIS 1, and ISIS 2 digital topside ionograms from selected original seven-track analog telemetry tapes. This project was initiated to preserve a significant portion of 60 satellite years of analog data, collected between 1962 and 1990, in digital form before the tapes were discarded. More than 1/2 million digital topside ionograms are now available for downloading at http://nssdcftp.gsfc.nasa.gov and for browsing and plotting at http://cdaweb.gsfc.nasa.gov. We illustrate data products, discuss analysis programs, review scientific results based on the digital data, and recognize those who made the project possible. The scientific results include evidence of extremely low altitude ionospheric peak densities at high latitudes, improved and new ionospheric models including one connecting the F2 topside ionosphere and the plasmasphere, transionospheric HF propagation investigations, and new interpretations of sounder-stimulated plasma emissions that have challenged theorists for decades. The homepage for the ISIS project is at http://nssdc.gsfc.nasa.gov/space/isis/isis-status.html.

Can Counter-Gang Models be Applied to Counter ISIS’s Internet Recruitment Campaign

DTIC Science & Technology

2016-06-10

limitation that exists is the lack of reliable statistics from social media companies in regards to the quantity of ISIS-affiliated sites, which exist on... statistics , they have approximately 320-million monthly active users with thirty-five-plus languages supported and 77 percent of accounts located...Justice and Delinquency Prevention program. For deterrence-based models, the primary point of research is focused deterrence models with emphasis placed

New Data on the Topside Electron Density Distribution

NASA Technical Reports Server (NTRS)

Huang, Xue-Qin; Reinisch, Bodo; Bilitza, Dieter; Benson, Robert F.

2001-01-01

The existing uncertainties about the electron density profiles in the topside ionosphere, i.e., in the height region from hmF2 to approx. 2000 km, require the search for new data sources. The ISIS and Alouette topside sounder satellites from the sixties to the eighties recorded millions of ionograms and most were not analyzed in terms of electron density profiles. In recent years an effort started to digitize the analog recordings to prepare the ionograms for computerized analysis. As of November 2001 about 350,000 ionograms have been digitized from the original 7-track analog tapes. These data are available in binary and CDF format from the anonymous ftp site of the National Space Science Data Center. A search site and browse capabilities on CDAWeb assist the scientific usage of these data. All information and access links can be found at http://nssdc.gsfc.nasa.gov/space/isis/isis-status.html. This paper describes the ISIS data restoration effort and shows how the digital ionograms are automatically processed into electron density profiles from satellite orbit altitude (1400 km for ISIS-2) down to the F peak. Because of the large volume of data an automated processing algorithm is imperative. The automatic topside ionogram scaler with true height algorithm TOPIST software developed for this task is successfully scaling approx.70 % of the ionograms. An 'editing process' is available to manually scale the more difficult ionograms. The automated processing of the digitized ISIS ionograms is now underway, producing a much-needed database of topside electron density profiles for ionospheric modeling covering more than one solar cycle. The ISIS data restoration efforts are supported through NASA's Applied Systems and Information Research Program.

New Data Source for Studying and Modelling the Topside Ionosphere

NASA Technical Reports Server (NTRS)

Huang, Xue-Qin; Reinisch, Bodo; Bilitza, Dieter; Benson, Robert

2001-01-01

The existing uncertainties about density profiles in the topside ionosphere, i.e., in the height regime from hmF2 to approx. 2000 km, requires the search for new data sources. Millions of ionograms had been recorded by the ISIS and Alouette satellites in the sixties and seventies, that never were analyzed in terms of electron density profiles. In recent years an effort started to digitize the analog recordings to prepare the ionograms for computerized analysis. This paper shows how the digital ionograms are processed and the electron density profiles (from satellite orbit altitude, 1400 km for ISIS-2, down to the F peak) are calculated. The most difficult part of the task is the automatic scaling of the echo traces in the ISIS ionograms. Unlike the ionograms from modern ionosondes, the ISIS ionograms do not identify the wave polarization of the different echo traces, so physical logic must be applied to identify the ordinary ()) and extraordinary (X) traces, and this is not always successful. Characteristic resonance features seen in the topside ionograms occur at the gyro and plasma frequencies. An elaborate scheme was developed to identify these resonance frequencies in order to determine the local plasma and gyrofrequencies. This information helps in the identification of the O and X traces, and it provides the starting density of the electron density profile. The inversion of the echo traces into electron density profiles uses the same modified Chebyshev polynomial fitting technique that is successfully applied in the ground-based Digisonde network. The automatic topside ionogram scaler with true height algorithm TOPIST is successfully scaling approx. 70% of the ionograms. An 'editing process' is available to manually scale the more difficult ionograms. The home page for the ISIS project is at http://nssdc.gsfc.nasa.gov/space/isis/isis-status.html. It provides access to as of January 2001, 3000,000 digitized ISIS ionogram data and to related software. A search page lets users select data location, time, and a host of other search criteria. The automated processing of the ISIS ionograms will begin later this year and the electron density profiles will be made available from the project home page. The ISIS data restoration efforts are supported through NASA's Applied Systems and Information Research Program.

Development of a prototype multi-processing interactive software invocation system

NASA Technical Reports Server (NTRS)

Berman, W. J.

1983-01-01

The Interactive Software Invocation System (NASA-ISIS) was first transported to the M68000 microcomputer, and then rewritten in the programming language Path Pascal. Path Pascal is a significantly enhanced derivative of Pascal, allowing concurrent algorithms to be expressed using the simple and elegant concept of Path Expressions. The primary results of this contract was to verify the viability of Path Pascal as a system's development language. The NASA-ISIS implementation using Path Pascal is a prototype of a large, interactive system in Path Pascal. As such, it is an excellent demonstration of the feasibility of using Path Pascal to write even more extensive systems. It is hoped that future efforts will build upon this research and, ultimately, that a full Path Pascal/ISIS Operating System (PPIOS) might be developed.

Identification and Characterization of the Iridoid Synthase Involved in Oleuropein Biosynthesis in Olive (Olea europaea) Fruits.

PubMed

Alagna, Fiammetta; Geu-Flores, Fernando; Kries, Hajo; Panara, Francesco; Baldoni, Luciana; O'Connor, Sarah E; Osbourn, Anne

2016-03-11

The secoiridoids are the main class of specialized metabolites present in olive (Olea europaea L.) fruit. In particular, the secoiridoid oleuropein strongly influences olive oil quality because of its bitterness, which is a desirable trait. In addition, oleuropein possesses a wide range of pharmacological properties, including antioxidant, anti-inflammatory, and anti-cancer activities. In accordance, obtaining high oleuropein varieties is a main goal of molecular breeding programs. Here we use a transcriptomic approach to identify candidate genes belonging to the secoiridoid pathway in olive. From these candidates, we have functionally characterized the olive homologue of iridoid synthase (OeISY), an unusual terpene cyclase that couples an NAD (P)H-dependent 1,4-reduction step with a subsequent cyclization, and we provide evidence that OeISY likely generates the monoterpene scaffold of oleuropein in olive fruits. OeISY, the first pathway gene characterized for this type of secoiridoid, is a potential target for breeding programs in a high value secoiridoid-accumulating species. © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

Leveraging ISI Multi-Model Prediction for Navy Operations: Proposal to the Office of Naval Research

DTIC Science & Technology

2013-09-30

Proposal to the Office of Naval Research James Kinter Director, Center for Ocean-Land-Atmosphere Studies Professor, Climate Dynamics...TYPE 3. DATES COVERED 00-00-2013 to 00-00-2013 4. TITLE AND SUBTITLE Leveraging ISI Multi-Model Prediction for Navy Operations: Proposal to the ... Office of Naval Research 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK

Advanced ISDN satellite designs and experiments

NASA Technical Reports Server (NTRS)

Pepin, Gerard R.

1992-01-01

The research performed by GTE Government Systems and the University of Colorado in support of the NASA Satellite Communications Applications Research (SCAR) Program is summarized. Two levels of research were undertaken. The first dealt with providing interim services Integrated Services Digital Network (ISDN) satellite (ISIS) capabilities that accented basic rate ISDN with a ground control similar to that of the Advanced Communications Technology Satellite (ACTS). The ISIS Network Model development represents satellite systems like the ACTS orbiting switch. The ultimate aim is to move these ACTS ground control functions on-board the next generation of ISDN communications satellite to provide full-service ISDN satellite (FSIS) capabilities. The technical and operational parameters for the advanced ISDN communications satellite design are obtainable from the simulation of ISIS and FSIS engineering software models of the major subsystems of the ISDN communications satellite architecture. Discrete event simulation experiments would generate data for analysis against NASA SCAR performance measure and the data obtained from the ISDN satellite terminal adapter hardware (ISTA) experiments, also developed in the program. The Basic and Option 1 phases of the program are also described and include the following: literature search, traffic mode, network model, scenario specifications, performance measures definitions, hardware experiment design, hardware experiment development, simulator design, and simulator development.

Zoos through the Lens of the IUCN Red List: A Global Metapopulation Approach to Support Conservation Breeding Programs

PubMed Central

Conde, Dalia A.; Colchero, Fernando; Gusset, Markus; Pearce-Kelly, Paul; Byers, Onnie; Flesness, Nate; Browne, Robert K.; Jones, Owen R.

2013-01-01

Given current extinction trends, the number of species requiring conservation breeding programs (CBPs) is likely to increase dramatically. To inform CBP policies for threatened terrestrial vertebrates, we evaluated the number and representation of threatened vertebrate species on the IUCN Red List held in the ISIS zoo network and estimated the complexity of their management as metapopulations. Our results show that 695 of the 3,955 (23%) terrestrial vertebrate species in ISIS zoos are threatened. Only two of the 59 taxonomic orders show a higher proportion of threatened species in ISIS zoos than would be expected if species were selected at random. In addition, for most taxa, the management of a zoo metapopulation of more than 250 individuals will require the coordination of a cluster of 11 to 24 ISIS zoos within a radius of 2,000 km. Thus, in the zoo network, the representation of species that may require CBPs is currently low and the spatial distribution of these zoo populations makes management difficult. Although the zoo community may have the will and the logistical potential to contribute to conservation actions, including CBPs, to do so will require greater collaboration between zoos and other institutions, alongside the development of international agreements that facilitate cross-border movement of zoo animals. To maximize the effectiveness of integrated conservation actions that include CBPs, it is fundamental that the non-zoo conservation community acknowledges and integrates the expertise and facilities of zoos where it can be helpful. PMID:24348999

Zoos through the lens of the IUCN Red List: a global metapopulation approach to support conservation breeding programs.

PubMed

Conde, Dalia A; Colchero, Fernando; Gusset, Markus; Pearce-Kelly, Paul; Byers, Onnie; Flesness, Nate; Browne, Robert K; Jones, Owen R

2013-01-01

Given current extinction trends, the number of species requiring conservation breeding programs (CBPs) is likely to increase dramatically. To inform CBP policies for threatened terrestrial vertebrates, we evaluated the number and representation of threatened vertebrate species on the IUCN Red List held in the ISIS zoo network and estimated the complexity of their management as metapopulations. Our results show that 695 of the 3,955 (23%) terrestrial vertebrate species in ISIS zoos are threatened. Only two of the 59 taxonomic orders show a higher proportion of threatened species in ISIS zoos than would be expected if species were selected at random. In addition, for most taxa, the management of a zoo metapopulation of more than 250 individuals will require the coordination of a cluster of 11 to 24 ISIS zoos within a radius of 2,000 km. Thus, in the zoo network, the representation of species that may require CBPs is currently low and the spatial distribution of these zoo populations makes management difficult. Although the zoo community may have the will and the logistical potential to contribute to conservation actions, including CBPs, to do so will require greater collaboration between zoos and other institutions, alongside the development of international agreements that facilitate cross-border movement of zoo animals. To maximize the effectiveness of integrated conservation actions that include CBPs, it is fundamental that the non-zoo conservation community acknowledges and integrates the expertise and facilities of zoos where it can be helpful.

In-service Inspection Ultrasonic Testing of Reactor Pressure Vessel Welds for Assessing Flaw Density and Size Distribution per 10 CFR 50.61a, Alternate Fracture Toughness Requirements

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sullivan, Edmund J.; Anderson, Michael T.; Norris, Wallace

2012-09-17

Pressurized thermal shock (PTS) events are system transients in a pressurized water reactor (PWR) in which there is a rapid operating temperature cool-down that results in cold vessel temperatures with or without repressurization of the vessel. The rapid cooling of the inside surface of the reactor pressure vessel (RPV) causes thermal stresses that can combine with stresses caused by high pressure. The aggregate effect of these stresses is an increase in the potential for fracture if a pre-existing flaw is present in a material susceptible to brittle failure. The ferritic, low alloy steel of the reactor vessel beltline adjacent tomore » the core, where neutron radiation gradually embrittles the material over the lifetime of the plant, can be susceptible to brittle fracture. The PTS rule, described in the Code of Federal Regulations, Title 10, Section 50.61 (§50.61), “Fracture Toughness Requirements for Protection against Pressurized Thermal Shock Events,” adopted on July 23, 1985, establishes screening criteria to ensure that the potential for a reactor vessel to fail due to a PTS event is deemed to be acceptably low. The U.S. Nuclear Regulatory Commission (NRC) completed a research program that concluded that the risk of through-wall cracking due to a PTS event is much lower than previously estimated. The NRC subsequently developed a rule, §50.61a, published on January 4, 2010, entitled “Alternate Fracture Toughness Requirements for Protection Against Pressurized Thermal Shock Events” (75 FR 13). Use of the new rule by licensees is optional. The §50.61a rule differs from §50.61 in that it requires licensees who choose to follow this alternate method to analyze the results from periodic volumetric examinations required by the ASME Code, Section XI, Rules for Inservice Inspection (ISI) of Nuclear Power Plants. These analyses are intended to determine if the actual flaw density and size distribution in the licensee’s reactor vessel beltline welds are bounded by the flaw density and size distribution values used in the PTS technical basis. Under a contract with the NRC, Pacific Northwest National Laboratory (PNNL) has been working on a program to assess the ability of current inservice inspection (ISI)-ultrasonic testing (UT) techniques, as qualified through ASME Code, Appendix VIII, Supplements 4 and 6, to detect small fabrication or inservice-induced flaws located in RPV welds and adjacent base materials. As part of this effort, the investigators have pursued an evaluation, based on the available information, of the capability of UT to provide flaw density/distribution inputs for making RPV weld assessments in accordance with §50.61a. This paper presents the results of an evaluation of data from the 1993 Browns Ferry Nuclear Plant, Unit 3, Spirit of Appendix VIII reactor vessel examination, a comparison of the flaw density/distribution from this data with the distribution in §50.61a, possible reasons for differences, and plans and recommendations for further work in this area.« less

Circulating natriuretic peptide concentrations reflect changes in insulin sensitivity over time in the Diabetes Prevention Program.

PubMed

Walford, Geoffrey A; Ma, Yong; Christophi, Costas A; Goldberg, Ronald B; Jarolim, Petr; Horton, Edward; Mather, Kieren J; Barrett-Connor, Elizabeth; Davis, Jaclyn; Florez, Jose C; Wang, Thomas J

2014-05-01

We aimed to study the relationship between measures of adiposity, insulin sensitivity and N-terminal pro-B-type natriuretic peptide (NT-proBNP) in the Diabetes Prevention Program (DPP). The DPP is a completed clinical trial. Using stored samples from this resource, we measured BMI, waist circumference (WC), an insulin sensitivity index (ISI; [1/HOMA-IR]) and NT-proBNP at baseline and at 2 years of follow-up in participants randomised to placebo (n = 692), intensive lifestyle intervention (n = 832) or metformin (n = 887). At baseline, log NT-proBNP did not differ between treatment arms and was correlated with baseline log ISI (p < 0.0001) and WC (p = 0.0003) but not with BMI (p = 0.39). After 2 years of treatment, BMI decreased in the lifestyle and metformin groups (both p < 0.0001); WC decreased in all three groups (p < 0.05 for all); and log ISI increased in the lifestyle and metformin groups (both p < 0.001). The change in log NT-proBNP did not differ in the lifestyle or metformin group vs the placebo group (p > 0.05 for both). In regression models, the change in log NT-proBNP was positively associated with the change in log ISI (p < 0.005) in all three study groups after adjusting for changes in BMI and WC, but was not associated with the change in BMI or WC after adjusting for changes in log ISI. Circulating NT-proBNP was associated with a measure of insulin sensitivity before and during preventive interventions for type 2 diabetes in the DPP. This relationship persisted after adjustment for measures of adiposity and was consistent regardless of whether a participant was treated with placebo, intensive lifestyle intervention or metformin.

Simulator design for advanced ISDN satellite design and experiments

NASA Technical Reports Server (NTRS)

Pepin, Gerald R.

1992-01-01

This simulation design task completion report documents the simulation techniques associated with the network models of both the Interim Service ISDN (integrated services digital network) Satellite (ISIS) and the Full Service ISDN Satellite (FSIS) architectures. The ISIS network model design represents satellite systems like the Advanced Communication Technology Satellite (ACTS) orbiting switch. The FSIS architecture, the ultimate aim of this element of the Satellite Communications Applications Research (SCAR) program, moves all control and switching functions on-board the next generation ISDN communication satellite. The technical and operational parameters for the advanced ISDN communications satellite design will be obtained from the simulation of ISIS and FSIS engineering software models for their major subsystems. Discrete events simulation experiments will be performed with these models using various traffic scenarios, design parameters and operational procedures. The data from these simulations will be used to determine the engineering parameters for the advanced ISDN communications satellite.

Effectiveness of Group Cognitive Behavioral Therapy for Insomnia (CBT-I) in a Primary Care Setting.

PubMed

Davidson, Judith R; Dawson, Samantha; Krsmanovic, Adrijana

2017-05-02

Primary care is where many patients with insomnia first ask for professional help. Cognitive-behavioral therapy for insomnia (CBT-I) is the recommended treatment for chronic insomnia. Although CBT-I's efficacy is well established, its effectiveness in real-life primary care has seldom been investigated. We examined the effectiveness of CBT-I as routinely delivered in a Canadian primary care setting. The patients were 70 women and 11 men (mean age = 57.0 years, SD = 12.3); 83% had medical comorbidity. For the first 81 patients who took the six-session group program we compared initial and postprogram sleep diaries, sleep medication use, Insomnia Severity Index (ISI), the Hospital Anxiety and Depression Scale (HADS), and visits to the family physician. Sleep onset latency, wake after sleep onset, total sleep time, sleep efficiency, and ISI scores improved significantly (p < .001). Mood ratings also improved (p < .001). Use of sleep medication decreased (p < .001). Effect sizes were medium to large. Eighty-eight percent of patients no longer had clinically significant insomnia (ISI score ≤ 14) by the last session; 61% showed at least "moderate" improvement (ISI score reduction > 7). Wait-list data from 42 patients showed minimal sleep and mood improvements with the passage of time. Number of visits to the family physician six months postprogram decreased, although not significantly (p = .108). The CBT-I program was associated with improvement on all sleep and mood measures. Effect sizes were similar to, or larger than, those found in randomized controlled trials, demonstrating the real-world effectiveness of CBT-I in an interdisciplinary primary care setting.

National Program for Inspection of Non-Federal Dams. Houghton Pond Dam (MA 00444), Charles River Basin, Holliston, Massachusetts. Phase I Inspection Report.

DTIC Science & Technology

1979-07-01

RD-A154 892 NATIONAL PROGRAM FOR INSPECTION OF NON-FEDERAL DAMS i/I HOUGHTON POND DAM (MA..(U) CORPS OF ENGINEERS WALTHAM UNCLASSIFIED N NEN ENGLAND...HOUGHTON POND DAM MA 00444 PHASE I INSPECTION REPORT _ NATIONAL DAM INSPECTION PROGRAM DTIC EECTE CD JUN4 985 -LJE DEPARTMENT OF THE ARMY NEW ENGLAND...16 SUPPLEMENTARY NOTES Co ver program reads: Phase I Inspection Report, National Dam Inspection Program ; however, the official title of the program

The Indiana Science Initiative: Lessons from a Classroom Observation Study

ERIC Educational Resources Information Center

Cook, Nicole D.; Walker, William S.; Weaver, Gabriela C.; Sorge, Brandon H.

2015-01-01

The Indiana Science Initiative (ISI) is a systemic effort to reform K-8 science education. The program provides teachers with professional development, reform-oriented science modules, and materials support. To examine the impact of the initiative's professional development, a participant observation study was conducted in the program's pilot…

Defense Research: Improved Management of DOD’s Technical Corrosion Collaboration Program Needed

DTIC Science & Technology

2014-05-01

Education and Research on Corrosion and Material Performance TCC Technical Corrosion Collaboration UCC University Corrosion Collaboration This is...is the successor to the University Corrosion Collaboration ( UCC ) pilot program, established in 2008. The TCC program builds on efforts of the UCC ...going from a pilot to a full program. They indicated that the UCC pilot program naturally evolved into the TCC pilot program in 2011, and the pilot

National Program for Inspection of Non-Federal Dams. Monsanto Company Upper Dam (MA 00573), Connecticut River Basin, Springfield, Massachusetts. Phase I Inspection Report.

DTIC Science & Technology

1978-10-01

DAM . * MA 00573 PHASE 1 INSPECTION REPORT NATIONAL DAM INSPECTION PROGRAM 0 V DEPARTMENT OF THE ARMY_ NEW ENGLAND DIVISION, CORPS OF ENGINEERS WALTHAM...ArIhtEN T (c- the 6b4trectenrto I lck 20, It dit.,.et i am Report) !6 5IPPLEMENTARY NOTES (,o ,er program reads: Phase I Inspection Report, National Darn...Inspection Program ; hov.ever, the official title of the program is: National Program for Inspection of lon-Federal Dans:. LISP cover date for date of

A minimax technique for time-domain design of preset digital equalizers using linear programming

NASA Technical Reports Server (NTRS)

Vaughn, G. L.; Houts, R. C.

1975-01-01

A linear programming technique is presented for the design of a preset finite-impulse response (FIR) digital filter to equalize the intersymbol interference (ISI) present in a baseband channel with known impulse response. A minimax technique is used which minimizes the maximum absolute error between the actual received waveform and a specified raised-cosine waveform. Transversal and frequency-sampling FIR digital filters are compared as to the accuracy of the approximation, the resultant ISI and the transmitted energy required. The transversal designs typically have slightly better waveform accuracy for a given distortion; however, the frequency-sampling equalizer uses fewer multipliers and requires less transmitted energy. A restricted transversal design is shown to use the least number of multipliers at the cost of a significant increase in energy and loss of waveform accuracy at the receiver.

14 CFR 91.1109 - Aircraft maintenance: Inspection program.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 2 2012-01-01 2012-01-01 false Aircraft maintenance: Inspection program... Ownership Operations Program Management § 91.1109 Aircraft maintenance: Inspection program. Each program... conduct of inspections for the particular make and model aircraft, including necessary tests and checks...

14 CFR 91.1109 - Aircraft maintenance: Inspection program.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Aircraft maintenance: Inspection program... Ownership Operations Program Management § 91.1109 Aircraft maintenance: Inspection program. Each program... conduct of inspections for the particular make and model aircraft, including necessary tests and checks...

14 CFR 91.1109 - Aircraft maintenance: Inspection program.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 2 2014-01-01 2014-01-01 false Aircraft maintenance: Inspection program... Ownership Operations Program Management § 91.1109 Aircraft maintenance: Inspection program. Each program... conduct of inspections for the particular make and model aircraft, including necessary tests and checks...

National Program for Inspection of Non-Federal Dams. Merino Pond Dam (MA 00110), Thames River Basin, Dudley, Massachusetts. Phase I Inspection Report.

DTIC Science & Technology

1979-09-01

of slm~ lu THAMES RIVER BASIN 00 DUDLEY, MASSACHUSETTS 0 0 in MERINO POND DAM MA 00110 0 PHASE I INSPECTION REPORT 0 NATIONAL DAM INSPECTION PROGRAM ...NATIONAL PROGRAM FOR INSPECTION OF NON-FEDERAL , e, .* f. ,,,-Ue I,. h TNw@ e 6, CONTACT OR IAUNT ONUWSaEPe* U.S. AMY CORPS OF ENGINEERS NEW ENGLAND...SAaUmN el ame 6 am vel NSON* Odlmwmn ba 00-0 o6. oll.I,,NIA*v mOTE& Cover program reads: Phase I Inspection Report, National Dam Inspection Program

76 FR 24713 - Cooperative Inspection Programs: Interstate Shipment of Meat and Poultry Products

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-02

...The Food Safety and Inspection Service (FSIS) is amending the Federal meat and poultry products inspection regulations to establish a new voluntary cooperative program under which State-inspected establishments with 25 or fewer employees will be eligible to ship meat and poultry products in interstate commerce. In participating States, State-inspected establishments selected to take part in this program will be required to comply with all Federal standards under the Federal Meat Inspection Act (FMIA) and the Poultry Products Inspection Act (PPIA). These establishments will receive inspection services from State inspection personnel that have been trained in the enforcement of the FMIA and PPIA. Meat and poultry products produced under the program that have been inspected and passed by designated State personnel will bear an official Federal mark of inspection and will be permitted to be distributed in interstate commerce. FSIS will provide oversight and enforcement of the program.

Member Perceptions of Informal Science Institution Graduate Certificate Program: Case Study of a Community of Practice

ERIC Educational Resources Information Center

Ball, Lois A.

2012-01-01

This research attempted to understand the experiences of a cohort of informal and formal science educators and informal science institution (ISI) community representatives during and after completion of a pilot graduate certificate program. Informal science educators (ISEs) find limited opportunities for professional development and support which…

Who is afraid of ISIS? ISIS anxiety and its correlates.

PubMed

Hoffman, Yaakov

2018-02-01

Islamic State of Iraq and the Levant (ISIS) is a relatively small organization, yet it wields its terror and media campaigns efficiently. Its presence has altered security measures in many western counties. In the current study, I assess anxiety of the ISIS threat and its correlates in a convenience sample of 1,007 adult Israelis (mean age = 29.61, SD = 7.16). Findings show that being female, a lower socioeconomic status, and having elevated post-traumatic stress disorder (PTSD) symptom levels were all associated with ISIS anxiety. Likewise, exposure to ISIS media, as well as having low resilience, was also correlated with ISIS anxiety. The correlations between ISIS anxiety on the one hand and ISIS media exposure, PTSD symptoms, and resilience on the other hand remained significant even after controlling for general anxiety symptoms. Finally, the PTSD- ISIS anxiety relationship was especially pronounced when resources (resilience/optimism) were low. This critical interaction also remained significant after controlling for general anxiety. Theoretical and practical ramifications of ISIS anxiety are discussed. Both resources for addressing current tasks (resilience), as well as those aimed at future outcomes (optimism), may be required for addressing ISIS anxiety, especially when PTSD symptoms are high. Copyright © 2017 John Wiley & Sons, Ltd.

National Dam Inspection Program. Lewis Lake Dam (NDI-ID Number PA-00061, DER-ID Number 58-7), Susquehanna River Basin, Susquehanna County, Pennsylvania. Phase I Inspection Report,

DTIC Science & Technology

1980-08-01

AD-A091 595 BERGER ASSOCIATES INC HARRISBURG PA FIG 13/13 NATIONAL DAM INSPECTION PROGRAM . LEWIS LAKE DAM (NDI-ID NUMBER -- ETC(U) AUG GO H JONGSMA...NO. 58-7 SUSQUEHANNA COUNTY, PENNSYLVANIA PHASE I INSPECTION REPORT NATIONAL DAM INSPECTION PROGRAM I 1 k-o C - PREPARED FOR DEPARTMENT OF THE ARMY...Dam Inspection Act, Public Law 92-367, authorized the Secretary of the Army, through the Corps of Engineers, to initiate a program of inspections of

Level of Service Program for INDOT Operations : APPENDIX A State Inspection Programs

DOT National Transportation Integrated Search

2012-01-01

INDOT has used an inspection program named Maintenance Quality Survey (MQS) to perform a statewide inspection of their roadway assets, rightofway to rightofway. This inspection requires two twoperson teams approximately 18 months to...

FMCSA safety program effectiveness measurement : Roadside Intervention Effectiveness Model FY 2012, [analysis brief].

DOT National Transportation Integrated Search

2016-02-01

Roadside Inspection and Traffic Enforcement are two of : the Federal Motor Carrier Safety Administrations : (FMCSAs) key safety programs. The Roadside : Inspection Program consists of roadside inspections : performed by qualified safety inspect...

Dynamic Changes of IsiA-Containing Complexes during Long-Term Iron Deficiency in Synechocystis sp. PCC 6803.

PubMed

Ma, Fei; Zhang, Xin; Zhu, Xi; Li, Tianpei; Zhan, Jiao; Chen, Hui; He, Chenliu; Wang, Qiang

2017-01-09

Iron stress-induced protein A (IsiA), a major chlorophyll-binding protein in the thylakoid membrane, is significantly induced under iron deficiency conditions. Using immunoblot analysis and 77 K fluorescence spectroscopy combined with sucrose gradient fractionation, we monitored dynamic changes of IsiA-containing complexes in Synechocystis sp. PCC 6803 during exposure to long-term iron deficiency. Within 3 days of exposure to iron deficiency conditions, the initially induced free IsiA proteins preferentially conjugated to PS I trimer to form IsiA 18 -PS I trimers, which serve as light energy collectors for efficiently transmitting energy to PS I. With prolonged iron deficiency, IsiA proteins assembled either into IsiA aggregates or into two other types of IsiA-PS I supercomplexes, namely IsiA-PS I high fluorescence supercomplex (IHFS) and IsiA-PS I low fluorescence supercomplex (ILFS). Further analysis revealed a role for IsiA as an energy dissipater in the IHFS and as an energy collector in the ILFS. The trimeric structure of PS I mediated by PsaL was found to be indispensable for the formation of IHFS/ILFS. Dynamic changes in IsiA-containing complexes in cyanobacteria during long-term iron deficiency may represent an adaptation to iron limitation stress for flexible light energy distribution, which balances electron transfer between PS I and PS II, thus minimizing photooxidative damage. Copyright © 2017 The Author. Published by Elsevier Inc. All rights reserved.

ISIS Topside-Sounder Plasma-Wave Investigations as Guides to Desired Virtual Wave Observatory (VWO) Data Search Capabilities

NASA Technical Reports Server (NTRS)

Benson, Robert F.; Fung, Shing F.

2008-01-01

Many plasma-wave phenomena, observed by space-borne radio sounders, cannot be properly explained in terms of wave propagation in a cold plasma consisting of mobile electrons and infinitely massive positive ions. These phenomena include signals known as plasma resonances. The principal resonances at the harmonics of the electron cyclotron frequency, the plasma frequency, and the upper-hybrid frequency are well explained by the warm-plasma propagation of sounder-generated electrostatic waves, Other resonances have been attributed to sounder-stimulated plasma instability and non-linear effects, eigenmodes of cylindrical electromagnetic plasma oscillations, and plasma memory processes. Data from the topside sounders of the International Satellites for Ionospheric Studies (ISIS) program played a major role in these interpretations. A data transformation and preservation effort at the Goddard Space Flight Center has produced digital ISIS topside ionograms and a metadata search program that has enabled some recent discoveries pertaining to the physics of these plasma resonances. For example, data records were obtained that enabled the long-standing question (several decades) of the origin of the plasma resonance at the fundamental electron cyclotron frequency to be explained [Muldrew, Radio Sci., 2006]. These data-search capabilities, and the science enabled by them, will be presented as a guide to desired data search capabilities to be included in the Virtual Wave Observatory (VWO).

32 CFR 310.44 - Inspection reporting.

Code of Federal Regulations, 2010 CFR

2010-07-01

... National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM DOD PRIVACY PROGRAM Inspections § 310.44 Inspection reporting. (a) Document the findings of the... appropriate, shall reflect overall assets of the Component Privacy Program inspected, or portion thereof...

VESUVIO: a novel instrument for performing spectroscopic studies in condensed matter with eV neutrons at the ISIS facility

NASA Astrophysics Data System (ADS)

Senesi, R.; Andreani, C.; Bowden, Z.; Colognesi, D.; Degiorgi, E.; Fielding, A. L.; Mayers, J.; Nardone, M.; Norris, J.; Praitano, M.; Rhodes, N. J.; Stirling, W. G.; Tomkinson, J.; Uden, C.

2000-03-01

The VESUVIO project aims to provide unique prototype instrumentation at the ISIS-pulsed neutron source and to establish a routine experimental and theoretical program in neutron scattering spectroscopy at eV energies. This instrumentation will be specifically designed for high momentum, (20 Å-11 eV) inelastic neutron scattering studies of microscopic dynamical processes in materials and will represent a unique facility for EU researchers. It will allow to derive single-particle kinetic energies and single-particle momentum distributions, n(p), providing additional and/or complementary information to other neutron inelastic spectroscopic techniques.

(abstract) Formal Inspection Technology Transfer Program

NASA Technical Reports Server (NTRS)

Welz, Linda A.; Kelly, John C.

1993-01-01

A Formal Inspection Technology Transfer Program, based on the inspection process developed by Michael Fagan at IBM, has been developed at JPL. The goal of this program is to support organizations wishing to use Formal Inspections to improve the quality of software and system level engineering products. The Technology Transfer Program provides start-up materials and assistance to help organizations establish their own Formal Inspection program. The course materials and certified instructors associated with the Technology Transfer Program have proven to be effective in classes taught at other NASA centers as well as at JPL. Formal Inspections (NASA tailored Fagan Inspections) are a set of technical reviews whose objective is to increase quality and reduce the cost of software development by detecting and correcting errors early. A primary feature of inspections is the removal of engineering errors before they amplify into larger and more costly problems downstream in the development process. Note that the word 'inspection' is used differently in software than in a manufacturing context. A Formal Inspection is a front-end quality enhancement technique, rather than a task conducted just prior to product shipment for the purpose of sorting defective systems (manufacturing usage). Formal Inspections are supporting and in agreement with the 'total quality' approach being adopted by many NASA centers.

Supporting Secure, AD HOC Joins for Tactical Networks

DTIC Science & Technology

2002-05-07

ftp.isi.edu/in-notes/ rfc2501.txt (20SEP01). [4] Deitel , Harvery M. and Paul J. Deitel . Java: How to Program 3rd Edition. (Prentice Hall: New...produce a complete product, to include the construction of TTNT hardware. The TTNT program is concerned with frequency hopping schemes, error correcting...Configuration To create the digital certificates needed for the client authentication, we modified a hybrid file encryption program that used a Rivest-Shamir

A Research Program in Computer Technology. 1986 Annual Technical Report

DTIC Science & Technology

1989-08-01

1986 (Annual Technical Report I July 1985 - June 1986 A Research Program in Computer Technology ISI/SR-87-178 U S C INFORMA-TION S C I EN C ES...Program in Computer Technology (Unclassified) 12. PERSONAL AUTHOR(S) 151 Research Staff 13a. TYPE OF REPORT 113b. TIME COVERED 14 DATE OF REPORT (Yeer...survivable networks 17. distributed processing, local networks, personal computers, workstation environment 18. computer acquisition, Strategic Computing 19

The ICAM-1 antisense oligonucleotide ISIS-3082 prevents the development of postoperative ileus in mice.

PubMed

The, Frans O; de Jonge, Wouter J; Bennink, Roel J; van den Wijngaard, Rene M; Boeckxstaens, Guy E

2005-09-01

Intestinal manipulation (IM) during abdominal surgery triggers the influx of inflammatory cells, leading to postoperative ileus. Prevention of this local muscle inflammation, using intercellular adhesion molecule-1 (ICAM-1) and leukocyte function-associated antigen-1-specific antibodies, has been shown to shorten postoperative ileus. However, the therapeutic use of antibodies has considerable disadvantages. The aim of the current study was to evaluate the effect of ISIS-3082, a mouse-specific ICAM-1 antisense oligonucleotide, on postoperative ileus in mice. Mice underwent a laparotomy or a laparotomy combined with IM after treatment with ICAM-1 antibodies, 0.1-10 mg kg(-1) ISIS-3082, saline or ISIS-8997 (scrambled control antisense oligonucleotides, 1 and 3 mg kg(-1)). At 24 h after surgery, gastric emptying of a 99mTC labelled semi-liquid meal was determined using scintigraphy. Intestinal inflammation was assessed by myeloperoxidase (MPO) activity in ileal muscle whole mounts. IM significantly reduced gastric emptying compared to laparotomy. Pretreatment with ISIS-3082 (0.1-1 mg kg(-1)) as well as ICAM-1 antibodies (10 mg kg(-1)), but not ISIS-8997 or saline, improved gastric emptying in a dose-dependent manner. This effect diminished with higher doses of ISIS-3082 (3-10 mg kg(-1)). Similarly, ISIS-3082 (0.1-1 mg kg(-1)) and ICAM-1 antibodies, but not ISIS-8997 or higher doses of ISIS-3082 (3-10 mg kg(-1)), reduced manipulation-induced inflammation. Immunohistochemistry showed reduction of ICAM-1 expression with ISIS-3082 only. ISIS-3082 pretreatment prevents postoperative ileus in mice by reduction of manipulation-induced local intestinal muscle inflammation. Our data suggest that targeting ICAM-1 using antisense oligonucleotides may represent a new therapeutic approach to the prevention of postoperative ileus.

Traffic Pattern Detection Using the Hough Transformation for Anomaly Detection to Improve Maritime Domain Awareness

DTIC Science & Technology

2013-12-01

Programming code in the Python language used in AIS data preprocessing is contained in Appendix A. The MATLAB programming code used to apply the Hough...described in Chapter III is applied to archived AIS data in this chapter. The implementation of the method, including programming techniques used, is...is contained in the second. To provide a proof of concept for the algorithm described in Chapter III, the PYTHON programming language was used for

FMCSA safety program effectiveness measurement : Roadside Intervention Effectiveness Model, fiscal year 2010 : [analysis brief].

DOT National Transportation Integrated Search

2014-11-01

Two of the Federal Motor Carrier Safety Administrations (FMCSAs) key safety programs are the Roadside Inspection and Traffic Enforcement programs. The Roadside Inspection program consists of roadside inspections performed by qualified safety in...

International ties. [international cooperation in the space sciences

NASA Technical Reports Server (NTRS)

1980-01-01

A historical overview of NASA's participation in international activities in space science is given. The Ariel, Alouette, Isis, and San Marco satellite programs are addressed along with sounding rocket and ground based projects. Relations and cooperation with the Soviet Union are also discussed.

9 CFR 592.400 - Who may request an appeal inspection or review of an inspection program employee's decision.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false Who may request an appeal inspection or review of an inspection program employee's decision. 592.400 Section 592.400 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION VOLUNTARY INSPECTION OF EGG PRODUCTS Appeals § 592.400...

9 CFR 592.400 - Who may request an appeal inspection or review of an inspection program employee's decision.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 9 Animals and Animal Products 2 2014-01-01 2014-01-01 false Who may request an appeal inspection or review of an inspection program employee's decision. 592.400 Section 592.400 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION VOLUNTARY INSPECTION OF EGG PRODUCTS Appeals § 592.400...

9 CFR 592.400 - Who may request an appeal inspection or review of an inspection program employee's decision.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Who may request an appeal inspection or review of an inspection program employee's decision. 592.400 Section 592.400 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION VOLUNTARY INSPECTION OF EGG PRODUCTS Appeals § 592.400...

9 CFR 592.400 - Who may request an appeal inspection or review of an inspection program employee's decision.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Who may request an appeal inspection or review of an inspection program employee's decision. 592.400 Section 592.400 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION VOLUNTARY INSPECTION OF EGG PRODUCTS Appeals § 592.400...

"Go! to Sleep": A Web-Based Therapy for Insomnia.

PubMed

Bernstein, Adam M; Allexandre, Didier; Bena, James; Doyle, Jonathan; Gendy, Gina; Wang, Lu; Fay, Susan; Mehra, Reena; Moul, Douglas; Foldvary-Schaefer, Nancy; Roizen, Michael F; Drerup, Michelle

2017-07-01

Insomnia is a common complaint of individuals presenting to healthcare providers and is associated with decreased quality of life and higher healthcare utilization. In-person cognitive behavioral therapy (CBT) is an effective treatment for insomnia but is hindered by cost and limited access to treatment. Initial research suggests that Web-based CBT may mitigate these obstacles. This study tests the effectiveness of a Web-based program for insomnia based on principles of CBT and stress management. We conducted a randomized trial with wait-list controls among adults with primary insomnia (n = 88). Two hundred sixty-three adults with comorbid insomnia were also included and analyzed separately. The intervention was a 6-week online program, and effectiveness was measured via the Insomnia Severity Index (ISI). Baseline ISI score for the intervention group (n = 43) was 17.0; 16.6 for the control group (n = 45). At first follow-up, the intervention group (n = 25) had a mean change from baseline of -7.3 (95% CI: -9.0, -5.6), sustained through second follow-up, while the control group (n = 35) had a change of -1.3 (-2.7, 0.1). The between-group difference was statistically significant (p < 0.001). Participants in the comorbid insomnia group had a baseline ISI score of 16.7 with improvement similar to the primary insomnia group (-6.9; -7.6, -6.2). We observed clinically meaningful improvements in insomnia severity in adults with primary or comorbid insomnia. Sustained improvement over 4 months underscores the effectiveness of a well-constructed online CBT for insomnia program. Go! to Sleep © offers a potentially effective treatment option for adults with insomnia by eliminating geographical barriers to care.

Housatonic River Basin, Danbury, Connecticut. Lower Kohanza Dam (CT 00064). National Dam Inspection Program. Phase I Inspection Report.

DTIC Science & Technology

1981-05-01

CONNECTICUT PHASE I INSPECTION REPORT’ I NATIONAL DAM INSPECTION PRGRAM 1 NATIONAL DAM INSPECTION PROGRAM PHASE I INSPECTION REPORT Identification No...of the toe of the aam and backtill the resulting voids with a suitable compacted material. Grass shoula be planted over the repairea areas to prevent

9 CFR 592.400 - Who may request an appeal inspection or review of an inspection program employee's decision.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Who may request an appeal inspection or review of an inspection program employee's decision. 592.400 Section 592.400 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION VOLUNTARY...

Evidence regarding patient compliance with incentive spirometry interventions after cardiac, thoracic and abdominal surgeries: A systematic literature review.

PubMed

Narayanan, Aqilah Leela T; Hamid, Syed Rasul G Syed; Supriyanto, Eko

2016-01-01

Evidence regarding the effectiveness of incentive spirometry (ISy) on postoperative pulmonary outcomes after thoracic, cardiac and abdominal surgery remains inconclusive. This is attributed to various methodological issues inherent in ISy trials. Patient compliance has also been highlighted as a possible confounding factor; however, the status of evidence regarding patient compliance in these trials is unknown. To explore the status of evidence on patient compliance with ISy interventions in randomized controlled trials (RCTs) in the above contexts. A systematic search using MEDLINE, EMBASE and CINAHL databases was conducted to obtain relevant RCTs from 1972 to 2015 using the inclusion criteria. These were examined for specific ISy parameters, methods used for determining compliance and reporting on compliance. Main outcome measures were comparison of ISy parameters prescribed and assessed, and reporting on compliance. Thirty-six relevant RCTs were obtained. Six ISy parameters were identified in ISy prescriptions from these trials. Almost all (97.2%) of the trials had ISy prescriptions with specific parameters. Wilcoxon signed-rank test revealed that the ISy parameters assessed were significantly lower (Z=-5.433; P<0.001) than those prescribed; 66.7% of the trials indicated use of various methods to assess these parameters. Only six (16.7%) trials included reports on compliance; however, these were also incomprehensive. There is a scarcity and inconsistency of evidence regarding ISy compliance. Compliance data should be obtained using reliable and standardized methods to facilitate comparisons between and among trials. These should be reported comprehensively to facilitate valid inferences regarding ISy intervention effectiveness.

Evidence regarding patient compliance with incentive spirometry interventions after cardiac, thoracic and abdominal surgeries: A systematic literature review

PubMed Central

Narayanan, Aqilah Leela T; Hamid, Syed Rasul G Syed; Supriyanto, Eko

2016-01-01

BACKGROUND: Evidence regarding the effectiveness of incentive spirometry (ISy) on postoperative pulmonary outcomes after thoracic, cardiac and abdominal surgery remains inconclusive. This is attributed to various methodological issues inherent in ISy trials. Patient compliance has also been highlighted as a possible confounding factor; however, the status of evidence regarding patient compliance in these trials is unknown. OBJECTIVE: To explore the status of evidence on patient compliance with ISy interventions in randomized controlled trials (RCTs) in the above contexts. METHOD: A systematic search using MEDLINE, EMBASE and CINAHL databases was conducted to obtain relevant RCTs from 1972 to 2015 using the inclusion criteria. These were examined for specific ISy parameters, methods used for determining compliance and reporting on compliance. Main outcome measures were comparison of ISy parameters prescribed and assessed, and reporting on compliance. RESULTS: Thirty-six relevant RCTs were obtained. Six ISy parameters were identified in ISy prescriptions from these trials. Almost all (97.2%) of the trials had ISy prescriptions with specific parameters. Wilcoxon signed-rank test revealed that the ISy parameters assessed were significantly lower (Z=−5.433; P<0.001) than those prescribed; 66.7% of the trials indicated use of various methods to assess these parameters. Only six (16.7%) trials included reports on compliance; however, these were also incomprehensive. CONCLUSIONS: There is a scarcity and inconsistency of evidence regarding ISy compliance. Compliance data should be obtained using reliable and standardized methods to facilitate comparisons between and among trials. These should be reported comprehensively to facilitate valid inferences regarding ISy intervention effectiveness. PMID:26909010

32 CFR 310.43 - Privacy Act inspections.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 2 2013-07-01 2013-07-01 false Privacy Act inspections. 310.43 Section 310.43 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM DOD PRIVACY PROGRAM Inspections § 310.43 Privacy Act inspections. During internal inspections...

32 CFR 310.43 - Privacy Act inspections.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 2 2014-07-01 2014-07-01 false Privacy Act inspections. 310.43 Section 310.43 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM DOD PRIVACY PROGRAM Inspections § 310.43 Privacy Act inspections. During internal inspections...

32 CFR 310.43 - Privacy Act inspections.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 2 2011-07-01 2011-07-01 false Privacy Act inspections. 310.43 Section 310.43 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM DOD PRIVACY PROGRAM Inspections § 310.43 Privacy Act inspections. During internal inspections...

32 CFR 310.43 - Privacy Act inspections.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 2 2012-07-01 2012-07-01 false Privacy Act inspections. 310.43 Section 310.43 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM DOD PRIVACY PROGRAM Inspections § 310.43 Privacy Act inspections. During internal inspections...

32 CFR 310.43 - Privacy Act inspections.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 2 2010-07-01 2010-07-01 false Privacy Act inspections. 310.43 Section 310.43 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM DOD PRIVACY PROGRAM Inspections § 310.43 Privacy Act inspections. During internal inspections...

Joint Logistics Commanders Guide for the Management of Multinational Program,

DTIC Science & Technology

1981-07-01

purchase of the A-300 Airbus and the 1977 record-breaking export performance of the French and UK aerospace industries of around $5 billion and $2 billion...DIS. They are the Defense Industrial Security Clearance Office ( DISCO ), the Defense Industrial Security Institute (DISI), and the Office of Industrial...Security International (ISI). Defense Industrial Security Clearance Office ( DISCO ) The Defense Industrial Security Program (DISP) establishes pro

Supporting large scale applications on networks of workstations

NASA Technical Reports Server (NTRS)

Cooper, Robert; Birman, Kenneth P.

1989-01-01

Distributed applications on networks of workstations are an increasingly common way to satisfy computing needs. However, existing mechanisms for distributed programming exhibit poor performance and reliability as application size increases. Extension of the ISIS distributed programming system to support large scale distributed applications by providing hierarchical process groups is discussed. Incorporation of hierarchy in the program structure and exploitation of this to limit the communication and storage required in any one component of the distributed system is examined.

25 CFR 170.507 - Who reviews bridge inspection reports?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 1 2011-04-01 2011-04-01 false Who reviews bridge inspection reports? 170.507 Section... ROADS PROGRAM Planning, Design, and Construction of Indian Reservation Roads Program Facilities Bridge Inspection § 170.507 Who reviews bridge inspection reports? The person responsible for the bridge inspection...

NDT applications in a successful fracture critical bridge inspection program and anchor bolt inspection program

NASA Astrophysics Data System (ADS)

Fish, Philip E.

1995-05-01

In 1978, Wisconsin Department of Transportation discovered major cracking on a two-girder, fracture critical structure, just four years after it was constructed. In 1981, on the same structure, now seven years old, major cracking was discovered in the tie girder flange of the tied arch span. This is one example of the type of failures that transportation departments discovered on welded structures in the 1970's and '80's. The failures from welded details and pinned connections lead to much stricter standards for present day designs. All areas were affected: design with identification of fatigue-prone details and classification of fatigue categories; material requirements with emphasis on toughness and weldability; increased welding and fabrication standards with licensure of fabrication shops to minimum quality standards including personnel; and an increased effort on inspection of existing bridges, where critical details were overlooked or missed in the past. FHWA inspection requirements for existing structures increased through this same time period, in reaction to the failures that had occurred. Obviously, many structures in Wisconsin were not built to the standards now required, thus the importance for quality inspection techniques. The new FHWA inspection requirements now being implemented throughout the nation require an in-depth, hands-on type inspection at a specified frequency, on all fracture critical structures. Wisconsin Department of Transportation started an in-depth inspection program in 1985 and made it a full time program in 1987. This program included extensive nondestructive testing. Ultrasonic inspection has played a major role in this type of inspection. All fracture critical structures, pin and hanger systems, and pinned connections are inspected on a five-year cycle now. The program requires an experienced inspection team and a practical inspection approach. Extensive preparation is required with review of all design, construction, and maintenance documents. An inspection plan is developed from the review and downloaded to a laptop computer. Inspection emphasis are on 'hands on' visual and nondestructive evaluation. Report documentation includes all design plans, pictorial documentation of structural deficiencies, nondestructive evaluation reports, conclusions, and recommendations. Planned changes in the program include implementation of an engineering work station as a 'single source' information file and reporting file for the inspection program. This would include scanning all current information into the file such as design, construction, and maintenance history. It would also include all inspection data with pictures. Inspections would be performed by downloading data onto a laptop and then uploading after completion of inspection. Pictures and nondestructive data would be entered by digital disks.

Level of Service Program for INDOT Operations : APPENDIX C Los Inspection Manual

DOT National Transportation Integrated Search

2012-01-01

INDOT has used an inspection program named Maintenance Quality Survey (MQS) to perform a statewide inspection of their roadway assets, rightofway to rightofway. This inspection requires two twoperson teams approximately 18 months to...

Blink reflex recovery cycle to differentiate Progressive Supranuclear Palsy from Cortico-basal syndrome.

PubMed

Sciacca, Giorgia; Nicoletti, Alessandra; Mostile, Giovanni; Luca, Antonina; Raciti, Loredana; Dibilio, Valeria; Drago, Filippo; Salomone, Salvatore; Zappia, Mario

2018-05-13

Progressive Supranuclear Palsy (PSP) and Cortico-basal syndrome (CBS) may share similar clinical findings and peculiar tests to distinguish between the two disorders could be useful. We evaluated Blink Reflex (BR) and R2 Blink Reflex Recovery Cycle (R2BRRC), determining diagnostic sensitivity, specificity, positive and negative predictive value of R2BRRC in differentiating PSP from CBS patients. This was a prospective data collection study investigating BR and R2BRRC at interstimulus intervals (ISIs) of 100, 150, 200, 300, 400, 500, 750 ms in 12 PSP patients, 8 CBS patients, and 10 controls. Patients with PSP have earlier recruitment of R2BRRC as compared to patients with CBS (ISI 100: p=0.002; ISI 150: p<0.001; ISI 200: p<0.001; ISI 300: p=0.02) and controls (ISI 100: p<0.001; ISI 150: p<0.001; ISI 200: p<0.001; ISI 300: p=0.004). The presence of an early recovery of the R2 differentiated PSP from CBS with specificity and sensitivity of 87.5% and 91.7% respectively. R2BRRC curve might be considered a useful tool in differentiating PSP from CBS patients. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Turbat, A.; Deschanels, H.; Sperandio, M.

The leak before break (LBB) concept was not used at the design level for SUPERPHENIX (SPX), but different studies have been performed or are in progress concerning different components : Main Vessel (MV), pipings. These studies were undertaken to improve the defense in depth, an approach used in all French reactors. In a first study, the LBB approach has been applied to the MV of SPX plant to verify the absence of risk as regards the core supporting function and to help in the definition of in-service inspection (ISI) program. Defining a reference semi-elliptic defect located in the welds ofmore » the structure, it is verified that the crack growth is limited and that the end-of-life defect is smaller than the critical one. Then it is shown that the hoop welds (those which are the most important for safety) located between the roof and the triple point verify the leak-before-break criteria. However, generally speaking, the low level of membrane primary stresses which is favorable for the integrity of the vessel makes the application of the leak-before-break concept more difficult due to small crack opening areas. Finally, the extension of the methodology to the secondary pipings of SPX incorporating recent European works of DCRC is briefly presented.« less

PRA and Risk Informed Analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bernsen, Sidney A.; Simonen, Fredric A.; Balkey, Kenneth R.

2006-01-01

The Boiler and Pressure Vessel Code (BPVC) of the American Society of Mechanical Engineers (ASME) has introduced a risk based approach into Section XI that covers Rules for Inservice Inspection of Nuclear Power Plant Components. The risk based approach requires application of the probabilistic risk assessments (PRA). Because no industry consensus standard existed for PRAs, ASME has developed a standard to evaluate the quality level of an available PRA needed to support a given risk based application. The paper describes the PRA standard, Section XI application of PRAs, and plans for broader applications of PRAs to other ASME nuclear codesmore » and standards. The paper addresses several specific topics of interest to Section XI. Important consideration are special methods (surrogate components) used to overcome the lack of PRA treatments of passive components in PRAs. The approach allows calculations of conditional core damage probabilities both for component failures that cause initiating events and failures in standby systems that decrease the availability of these systems. The paper relates the explicit risk based methods of the new Section XI code cases to the implicit consideration of risk used in the development of Section XI. Other topics include the needed interactions of ISI engineers, plant operating staff, PRA specialists, and members of expert panels that review the risk based programs.« less

Associations between dairy cow inter-service interval and probability of conception.

PubMed

Remnant, J G; Green, M J; Huxley, J N; Hudson, C D

2018-07-01

Recent research has indicated that the interval between inseminations in modern dairy cattle is often longer than the commonly accepted cycle length of 18-24 days. This study analysed 257,396 inseminations in 75,745 cows from 312 herds in England and Wales. The interval between subsequent inseminations in the same cow in the same lactation (inter-service interval, ISI) were calculated and inseminations categorised as successful or unsuccessful depending on whether there was a corresponding calving event. Conception risk was calculated for each individual ISI between 16 and 28 days. A random effects logistic regression model was fitted to the data with pregnancy as the outcome variable and ISI (in days) included in the model as a categorical variable. The modal ISI was 22 days and the peak conception risk was 44% for ISIs of 21 days rising from 27% at 16 days. The logistic regression model revealed significant associations of conception risk with ISI as well as 305 day milk yield, insemination number, parity and days in milk. Predicted conception risk was lower for ISIs of 16, 17 and 18 days and higher for ISIs of 20, 21 and 22 days compared to 25 day ISIs. A mixture model was specified to identify clusters in insemination frequency and conception risk for ISIs between 3 and 50 days. A "high conception risk, high insemination frequency" cluster was identified between 19 and 26 days which indicated that this time period was the true latent distribution for ISI with optimal reproductive outcome. These findings suggest that the period of increased numbers of inseminations around 22 days identified in existing work coincides with the period of increased probability of conception and therefore likely represents true return estrus events. Copyright © 2018 Elsevier Inc. All rights reserved.

FMCSA safety program effectiveness measurement : roadside intervention effectiveness model FY 2011 : [analysis brief].

DOT National Transportation Integrated Search

2015-06-01

Roadside Inspection and Traffic Enforcement are two of the Federal Motor Carrier Safety Administrations (FMCSAs) key safety programs. The Roadside Inspection program consists of roadside inspections performed by qualified safety inspectors. The...

Transcranial electric stimulation for intraoperative motor evoked potential monitoring: dependence of required stimulation current on interstimulus interval value.

PubMed

Joksimovic, Boban; Szelenyi, Andrea; Seifert, Volker; Damjanovic, Aleksandar; Damjanovic, Aleksandra; Rasulic, Lukas

2015-05-01

To evaluate the relationship between stimulus intensity by constant current transcranial electric stimulation and interstimulus interval (ISI) for eliciting muscle motor evoked potentials (MEPs) in three different hand muscles and the tibialis anterior muscles. We tested intraoperatively different monophasic constant current pulses and ISIs in 22 patients with clinically normal motor function. Motor thresholds of contralateral muscle MEPs were determined at 0.5 milliseconds (ms) pulse duration and ISIs of 1, 2, 3, 4, 5, and 10 ms using a train of 2, 3, and 5 monophasic constant current pulses of 62 to 104 mA before craniotomy and after closure of the dura mater. The lowest stimulation threshold to elicit MEPs in the examined muscles was achieved with a train of 5 pulses (ISI: 3 ms) before craniotomy, which was statistically significant compared with 2 pulses (ISI: 3 ms) as well as 3 pulses (ISIs: 3 and 10 ms). An ISI of 3 ms gave the lowest motor thresholds with statistical significance compared with the ISIs of 4 ms (2 pulses) and of 1 ms (3 pulses). All current intensity (mA) and ISI (ms) relationship graphs had a trend of the exponential function as y = a + bx + c ρ (x), where y is intensity (mA) and x is ISI (ms). The minimum of the function was determined for each patient and each muscle. The difference was statistically significant between 3 and 5 pulses before craniotomy and between 3 and 5 pulses and 2 and 5 pulses after closure of the dura mater. In adult neurosurgical patients with a normal motor status, a train of 5 pulses and an ISI of 3 ms provide the lowest motor thresholds. We provided evidence of the dependence of required stimulation current on ISI. Georg Thieme Verlag KG Stuttgart · New York.

The ICAM-1 antisense oligonucleotide ISIS-3082 prevents the development of postoperative ileus in mice

PubMed Central

The, Frans O; de Jonge, Wouter J; Bennink, Roel J; van den Wijngaard, Rene M; Boeckxstaens, Guy E

2005-01-01

Intestinal manipulation (IM) during abdominal surgery triggers the influx of inflammatory cells, leading to postoperative ileus. Prevention of this local muscle inflammation, using intercellular adhesion molecule-1 (ICAM-1) and leukocyte function-associated antigen-1-specific antibodies, has been shown to shorten postoperative ileus. However, the therapeutic use of antibodies has considerable disadvantages. The aim of the current study was to evaluate the effect of ISIS-3082, a mouse-specific ICAM-1 antisense oligonucleotide, on postoperative ileus in mice. Mice underwent a laparotomy or a laparotomy combined with IM after treatment with ICAM-1 antibodies, 0.1–10 mg kg−1 ISIS-3082, saline or ISIS-8997 (scrambled control antisense oligonucleotides, 1 and 3 mg kg−1). At 24 h after surgery, gastric emptying of a 99mTC labelled semi-liquid meal was determined using scintigraphy. Intestinal inflammation was assessed by myeloperoxidase (MPO) activity in ileal muscle whole mounts. IM significantly reduced gastric emptying compared to laparotomy. Pretreatment with ISIS-3082 (0.1–1 mg kg−1) as well as ICAM-1 antibodies (10 mg kg−1), but not ISIS-8997 or saline, improved gastric emptying in a dose-dependent manner. This effect diminished with higher doses of ISIS-3082 (3–10 mg kg−1). Similarly, ISIS-3082 (0.1–1 mg kg−1) and ICAM-1 antibodies, but not ISIS-8997 or higher doses of ISIS-3082 (3–10 mg kg−1), reduced manipulation-induced inflammation. Immunohistochemistry showed reduction of ICAM-1 expression with ISIS-3082 only. ISIS-3082 pretreatment prevents postoperative ileus in mice by reduction of manipulation-induced local intestinal muscle inflammation. Our data suggest that targeting ICAM-1 using antisense oligonucleotides may represent a new therapeutic approach to the prevention of postoperative ileus. PMID:15997238

Lack of pharmacokinetic interaction for ISIS 113715, a 2'-0-methoxyethyl modified antisense oligonucleotide targeting protein tyrosine phosphatase 1B messenger RNA, with oral antidiabetic compounds metformin, glipizide or rosiglitazone.

PubMed

Geary, Richard S; Bradley, JoAnn D; Watanabe, Tanya; Kwon, Younggil; Wedel, Mark; van Lier, Jan J; VanVliet, André A

2006-01-01

ISIS 113715 is a 20-mer phosphorothioate antisense oligonucleotide (ASO) that is complementary to the protein tyrosine phosphatase 1B (PTP-1B) messenger RNA and subsequently reduces translation of the PTP-1B protein, a negative regulator of insulin receptor. ISIS 113715 is currently being studied in early phase II clinical studies to determine its ability to improve or restore insulin receptor sensitivity in patients with type 2 diabetes mellitus. Future work will investigate the combination of ISIS 113715 with antidiabetic compounds. In vitro ultrafiltration human plasma protein binding displacement studies and a phase I clinical study were used to characterise the potential for pharmacokinetic interaction of ISIS 113715 and three marketed oral antidiabetic agents. ISIS 113715 was co-incubated with glipizide and rosiglitazone in whole human plasma and tested for increased free drug concentrations. In a phase I clinical study, 23 healthy volunteers received a single oral dose of an antidiabetic compound (either metformin, glipizide or rosiglitazone) both alone and together with subcutaneous ISIS 113715 200 mg in a sequential crossover design. A comparative pharmacokinetic analysis was performed to determine if there were any effects that resulted from coadministration of ISIS 113715 with these antidiabetic compounds. In vitro human plasma protein binding displacement studies showed only minor effects on rosiglitazone and no effect on glipizide when co-incubated with ISIS 113715. The results of the phase I clinical study further indicate that there were no measurable changes in glipizide (5 mg), metformin (500 mg) or rosiglitazone (2 mg) exposure parameters, maximum plasma concentration and the area under the concentration-time curve, or pharmacokinetic parameter, elimination half-life when coadministered with ISIS 113715. Furthermore, there was no effect of ISIS 113715, administered in combination with metformin, on the urinary excretion of metformin. Conversely, there were no observed alterations in ISIS 113715 pharmacokinetics when administered in combination with any of the oral antidiabetic compounds. These data provide evidence that ISIS 113715 exhibits no clinically relevant pharmacokinetic interactions on the disposition and clearance of the oral antidiabetic drugs. The results of these studies support further study of ISIS 113715 in combination with antidiabetic compounds.

To What Extent Does Isis Mark a New Stage in the Development of Salafi-Jihadism

DTIC Science & Technology

This thesis examines whether the Islamic State of Iraq and Syria (ISIS) marks a new stage in the development of Salafi-jihadism. Based on a thorough...of media are additional new characteristics that distinguish ISIS from the other Salafi-jihadist groups. The thesis concludes that ISIS marks a new

Computerized fracture critical and specialized bridge inspection program with NDE applications

NASA Astrophysics Data System (ADS)

Fish, Philip E.

1998-03-01

Wisconsin Department of Transportation implemented a Fracture Critical & Specialized Inspection Program in 1987. The program has a strong emphasis on Nondestructive Testing (NDT). The program is also completely computerized, using laptop computers to gather field data, digital cameras for pictures, and testing equipment with download features. Final inspection reports with detailed information can be delivered within days of the inspection. The program requires an experienced inspection team and qualified personnel. Individuals performing testing must be licensed ASNT (American Society for Nondestructive Testing) Level III and must be licensed Certified Weld Inspectors (American Welding Society). Several critical steps have been developed to assure that each inspection identifies all possible deficiencies that may be possible on a Fracture Critical or Unique Bridge. They include; review of all existing plans and maintenance history; identification of fracture critical members, identification of critical connection details, welds, & fatigue prone details, development of visual and NDE inspection plan; field inspection procedures; and a detailed formal report. The program has found several bridges with critical fatigue conditions which have resulted in replacement or major rehabilitation. In addition, remote monitoring systems have been installed on structures with serious cracking to monitor for changing conditions.

Enhancing Teaching Excellence through a Scientist-Science Teacher Collaborative Process.

ERIC Educational Resources Information Center

Haakonsen, Harry; And Others

1993-01-01

The Institute for Science Instruction and Study (ISIS) at Southern Connecticut State University was established to place experienced science teachers in extended contact with a variety of research scientists working at the cutting edge of their fields. Reports program goals, format, requirements, and evaluation. (LZ)

Y-12 Groundwater Protection Program CY2012 Triennial Report Of The Monitoring Well Inspection And Maintenance Program Y-12 National Security Complex, Oak Ridge, Tennessee

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2013-09-01

This document is the triennial report for the Well Inspection and Maintenance Program of the Y- 12 Groundwater Protection Program (GWPP), at the U.S. Department of Energy (DOE) Y-12 National Security Complex (Y-12). This report formally documents well inspections completed by the GWPP on active and inactive wells at Y-12 during calendar years (CY) 2010 through 2012. In addition, this report also documents well inspections performed under the Y-12 Water Resources Restoration Program, which is administered by URS|CH2M Oak Ridge (UCOR). This report documents well maintenance activities completed since the last triennial inspection event (CY 2009); and provides summary tablesmore » of well inspections and well maintenance activities during the reference time period.« less

9 CFR 592.90 - Authority and duties of inspection program personnel performing service.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Authority and duties of inspection program personnel performing service. 592.90 Section 592.90 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION VOLUNTARY INSPECTION OF EGG PRODUCTS Performance of Services § 592.90 Authorit...

9 CFR 592.90 - Authority and duties of inspection program personnel performing service.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 9 Animals and Animal Products 2 2014-01-01 2014-01-01 false Authority and duties of inspection program personnel performing service. 592.90 Section 592.90 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION VOLUNTARY INSPECTION OF EGG PRODUCTS Performance of Services § 592.90 Authorit...

9 CFR 592.90 - Authority and duties of inspection program personnel performing service.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false Authority and duties of inspection program personnel performing service. 592.90 Section 592.90 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION VOLUNTARY INSPECTION OF EGG PRODUCTS Performance of Services § 592.90 Authorit...

Implementation of the Air Program Information Management System (APIMS) Inspection Module

DTIC Science & Technology

2009-05-01

7 5 T H A I R B A S E W I N G Implementation of the Air Program Information Management System (APIMS) Inspection Module 2009 Environment...Implementation of the Air Program Information Management System (APIMS) Inspection Module 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER

14 CFR 135.419 - Approved aircraft inspection program.

Code of Federal Regulations, 2010 CFR

2010-01-01

... OPERATING REQUIREMENTS: COMMUTER AND ON DEMAND OPERATIONS AND RULES GOVERNING PERSONS ON BOARD SUCH AIRCRAFT Maintenance, Preventive Maintenance, and Alterations § 135.419 Approved aircraft inspection program. (a... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Approved aircraft inspection program. 135...

14 CFR 135.419 - Approved aircraft inspection program.

Code of Federal Regulations, 2012 CFR

2012-01-01

... OPERATING REQUIREMENTS: COMMUTER AND ON DEMAND OPERATIONS AND RULES GOVERNING PERSONS ON BOARD SUCH AIRCRAFT Maintenance, Preventive Maintenance, and Alterations § 135.419 Approved aircraft inspection program. (a... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Approved aircraft inspection program. 135...

14 CFR 135.419 - Approved aircraft inspection program.

Code of Federal Regulations, 2013 CFR

2013-01-01

... OPERATING REQUIREMENTS: COMMUTER AND ON DEMAND OPERATIONS AND RULES GOVERNING PERSONS ON BOARD SUCH AIRCRAFT Maintenance, Preventive Maintenance, and Alterations § 135.419 Approved aircraft inspection program. (a... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Approved aircraft inspection program. 135...

14 CFR 135.419 - Approved aircraft inspection program.

Code of Federal Regulations, 2014 CFR

2014-01-01

... OPERATING REQUIREMENTS: COMMUTER AND ON DEMAND OPERATIONS AND RULES GOVERNING PERSONS ON BOARD SUCH AIRCRAFT Maintenance, Preventive Maintenance, and Alterations § 135.419 Approved aircraft inspection program. (a... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Approved aircraft inspection program. 135...

14 CFR 135.419 - Approved aircraft inspection program.

Code of Federal Regulations, 2011 CFR

2011-01-01

... OPERATING REQUIREMENTS: COMMUTER AND ON DEMAND OPERATIONS AND RULES GOVERNING PERSONS ON BOARD SUCH AIRCRAFT Maintenance, Preventive Maintenance, and Alterations § 135.419 Approved aircraft inspection program. (a... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Approved aircraft inspection program. 135...

Applying program comprehension techniques to improve software inspections

NASA Technical Reports Server (NTRS)

Rifkin, Stan; Deimel, Lionel

1994-01-01

Software inspections are widely regarded as a cost-effective mechanism for removing defects in software, though performing them does not always reduce the number of customer-discovered defects. We present a case study in which an attempt was made to reduce such defects through inspection training that introduced program comprehension ideas. The training was designed to address the problem of understanding the artifact being reviewed, as well as other perceived deficiencies of the inspection process itself. Measures, both formal and informal, suggest that explicit training in program understanding may improve inspection effectiveness.

40 CFR 52.241 - Inspection and maintenance program.

Code of Federal Regulations, 2011 CFR

2011-07-01

... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.241 Inspection and maintenance program. (a) [Reserved] (b) Approval. On June 5, 2009, the California Air Resources Board submitted a revision to the California Motor Vehicle Inspection and Maintenance Program (2009 I/M Revision) to satisfy...

40 CFR 52.241 - Inspection and maintenance program.

Code of Federal Regulations, 2014 CFR

2014-07-01

... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.241 Inspection and maintenance program. (a) [Reserved] (b) Approval. On June 5, 2009, the California Air Resources Board submitted a revision to the California Motor Vehicle Inspection and Maintenance Program (2009 I/M Revision) to satisfy...

40 CFR 52.241 - Inspection and maintenance program.

Code of Federal Regulations, 2013 CFR

2013-07-01

... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.241 Inspection and maintenance program. (a) [Reserved] (b) Approval. On June 5, 2009, the California Air Resources Board submitted a revision to the California Motor Vehicle Inspection and Maintenance Program (2009 I/M Revision) to satisfy...

40 CFR 52.241 - Inspection and maintenance program.

Code of Federal Regulations, 2012 CFR

2012-07-01

... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.241 Inspection and maintenance program. (a) [Reserved] (b) Approval. On June 5, 2009, the California Air Resources Board submitted a revision to the California Motor Vehicle Inspection and Maintenance Program (2009 I/M Revision) to satisfy...

Matsuda-DeFronzo insulin sensitivity index is a better predictor than HOMA-IR of hypertension in Japanese: the Tanno-Sobetsu study.

PubMed

Furugen, M; Saitoh, S; Ohnishi, H; Akasaka, H; Mitsumata, K; Chiba, M; Furukawa, T; Miyazaki, Y; Shimamoto, K; Miura, T

2012-05-01

Here we examined whether the Matsuda-DeFronzo insulin sensitivity index (ISI-M) is more efficient than the homeostasis model assessment of insulin resistance (HOMA-IR) for assessing risk of hypertension. Cross-sectional and longitudinal analyses were conducted using normotensive subjects who were selected among 1399 subjects in the Tanno-Sobetsu cohort. In the cross-sectional analysis (n=740), blood pressure (BP) level was correlated with HOMA-IR and with ISI-M, but correlation coefficients indicate a tighter correlation with ISI-M. Multiple linear regression analysis adjusted by age, sex, body mass index (BMI) and serum triglyceride level (TG) showed contribution of ISI-M and fasting plasma glucose, but not of HOMA-IR. In the longitudinal analysis (n=607), 241 subjects (39.7%) developed hypertension during a 10-year follow-up period, and multiple logistic regression indicated that age, TG, systolic BP and ISI-M, but not HOMA-IR, were associated with development of hypertension. In subjects <60 years old, odds ratio of new-onset hypertension was higher in the low ISI-M group (ISI-M, less than the median) than in the high ISI-M group for any tertile of BMI. In conclusion, ISI-M is a better predictor of hypertension than is HOMA-IR. Non-hepatic IR may be a determinant, which is independent of TG, BP level and BMI, of the development of hypertension.

7 CFR 1948.91 - Inspections of development.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 13 2011-01-01 2009-01-01 true Inspections of development. 1948.91 Section 1948.91...) PROGRAM REGULATIONS (CONTINUED) RURAL DEVELOPMENT Section 601 Energy Impacted Area Development Assistance Program § 1948.91 Inspections of development. Inspections will be made by the FmHA or its successor agency...

42 CFR 493.571 - Disclosure of accreditation, State and CMS validation inspection results.

Code of Federal Regulations, 2013 CFR

2013-10-01

... validation inspection results. 493.571 Section 493.571 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES... Program § 493.571 Disclosure of accreditation, State and CMS validation inspection results. (a... licensure program, in accordance with State law. (c) CMS validation inspection results. CMS may disclose the...

42 CFR 493.571 - Disclosure of accreditation, State and CMS validation inspection results.

Code of Federal Regulations, 2011 CFR

2011-10-01

... validation inspection results. 493.571 Section 493.571 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES... Program § 493.571 Disclosure of accreditation, State and CMS validation inspection results. (a... licensure program, in accordance with State law. (c) CMS validation inspection results. CMS may disclose the...

42 CFR 493.571 - Disclosure of accreditation, State and CMS validation inspection results.

Code of Federal Regulations, 2012 CFR

2012-10-01

... validation inspection results. 493.571 Section 493.571 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES... Program § 493.571 Disclosure of accreditation, State and CMS validation inspection results. (a... licensure program, in accordance with State law. (c) CMS validation inspection results. CMS may disclose the...

42 CFR 493.571 - Disclosure of accreditation, State and CMS validation inspection results.

Code of Federal Regulations, 2010 CFR

2010-10-01

... validation inspection results. 493.571 Section 493.571 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES... Program § 493.571 Disclosure of accreditation, State and CMS validation inspection results. (a... licensure program, in accordance with State law. (c) CMS validation inspection results. CMS may disclose the...

42 CFR 493.571 - Disclosure of accreditation, State and CMS validation inspection results.

Code of Federal Regulations, 2014 CFR

2014-10-01

... validation inspection results. 493.571 Section 493.571 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES... Program § 493.571 Disclosure of accreditation, State and CMS validation inspection results. (a... licensure program, in accordance with State law. (c) CMS validation inspection results. CMS may disclose the...

The ISI Tunnel

DTIC Science & Technology

1993-10-01

INFORMATION SCIENCES 310/822-1511 INSTITUTE 4676 Admrraltp Wa.v/Marina del Rev/calfornia 90292-6695 The ISI "Tunnel" Annette DeSchon and Danny Cohen...ISI/SR-93-358 October 1993 University of Southern California Information Sciences Institute 4676 Adniralry Way, Marina del Rey, CA 90292-6695 310-822...ES) B. PERFORMING ORGANIZATION USC/ Information Science Institute 4676 Admiralty Way ISI/SR-93-358 Marina del Rey, CA 90292-6695 2. SPONSORING

Postgraduate Students' Experiences and Attitudes Towards isiZulu as a Medium of Instruction at the University of KwaZulu-Natal

ERIC Educational Resources Information Center

Nkosi, Zinhle Primrose

2014-01-01

IsiZulu is one of the 11 official languages of South Africa and has the highest number of speakers in the country. While the South African Language Policy for Higher Education (2002) emphasizes the need to use African languages at universities, not many universities' isiZulu-speaking students prefer to be taught in isiZulu. Research has revealed…

9 CFR 592.95 - Facilities and equipment to be furnished for use of inspection program personnel in performing...

Code of Federal Regulations, 2012 CFR

2012-01-01

... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Facilities and equipment to be furnished for use of inspection program personnel in performing service. 592.95 Section 592.95 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION VOLUNTARY INSPECTION OF EGG PRODUCTS Performanc...

9 CFR 592.95 - Facilities and equipment to be furnished for use of inspection program personnel in performing...

Code of Federal Regulations, 2013 CFR

2013-01-01

... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false Facilities and equipment to be furnished for use of inspection program personnel in performing service. 592.95 Section 592.95 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION VOLUNTARY INSPECTION OF EGG PRODUCTS Performanc...

9 CFR 592.95 - Facilities and equipment to be furnished for use of inspection program personnel in performing...

Code of Federal Regulations, 2011 CFR

2011-01-01

... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Facilities and equipment to be furnished for use of inspection program personnel in performing service. 592.95 Section 592.95 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION VOLUNTARY INSPECTION OF EGG PRODUCTS Performanc...

9 CFR 592.95 - Facilities and equipment to be furnished for use of inspection program personnel in performing...

Code of Federal Regulations, 2014 CFR

2014-01-01

... 9 Animals and Animal Products 2 2014-01-01 2014-01-01 false Facilities and equipment to be furnished for use of inspection program personnel in performing service. 592.95 Section 592.95 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION VOLUNTARY INSPECTION OF EGG PRODUCTS Performanc...

Level of Service Program for INDOT Operations

DOT National Transportation Integrated Search

2012-08-01

INDOT has used an inspection program named Maintenance Quality Survey (MQS) to perform a statewide inspection of their roadway : assets, rightofway to rightofway. This inspection requires two twoperson teams approximately 18 months ...

Thermographic Inspections And The Residential Conservation Service Program (RCS)

NASA Astrophysics Data System (ADS)

Ward, Ronald J.

1983-03-01

Rhode Islanders Saving Energy (RISE) is a non-profit corporation founded in 1977 to provide Rhode Island residents with a variety of energy conservation services. Since January of 1981, it has been performing energy audits in compliance with the Department of Energy's (DOE) Residential Conservation Service Program (RCS). One aspect of the RCS program is the performance of inspections on energy conservation activities completed according to RCS installation guidelines. This paper will describe both the use and results of thermographic inspections within the RISE program. The primary objective of these inspections has been to assure the quality of the building envelope after completion of retrofit measures. Thermal anamolies have been detected that vary in size, location and probable cause. Approximately 37% of all jobs performed through RISE in conjunction with the RCS program have required remedial work as a result of problems that were identi-fied during the thermographic inspection. This percentage was much higher when infra-red inspections were conducted on "Non-RCS" retrofits. Statistics will be presented that provide an interesting insight on the quality of retrofit work when performed in associa-tion with a constant inspection process.

Online extremism and the communities that sustain it: Detecting the ISIS supporting community on Twitter.

PubMed

Benigni, Matthew C; Joseph, Kenneth; Carley, Kathleen M

2017-01-01

The Islamic State of Iraq and ash-Sham (ISIS) continues to use social media as an essential element of its campaign to motivate support. On Twitter, ISIS' unique ability to leverage unaffiliated sympathizers that simply retweet propaganda has been identified as a primary mechanism in their success in motivating both recruitment and "lone wolf" attacks. The present work explores a large community of Twitter users whose activity supports ISIS propaganda diffusion in varying degrees. Within this ISIS supporting community, we observe a diverse range of actor types, including fighters, propagandists, recruiters, religious scholars, and unaffiliated sympathizers. The interaction between these users offers unique insight into the people and narratives critical to ISIS' sustainment. In their entirety, we refer to this diverse set of users as an online extremist community or OEC. We present Iterative Vertex Clustering and Classification (IVCC), a scalable analytic approach for OEC detection in annotated heterogeneous networks, and provide an illustrative case study of an online community of over 22,000 Twitter users whose online behavior directly advocates support for ISIS or contibutes to the group's propaganda dissemination through retweets.

Level of Service Program for INDOT Operations

DOT National Transportation Integrated Search

2012-08-01

INDOT has used an inspection program named Maintenance Quality Survey (MQS) to perform a statewide inspection of their roadway assets, rightofway to rightofway. This inspection requires two twoperson teams approximately 18 months to...

9 CFR 327.6 - Products for importation; program inspection, time and place; application for approval of...

Code of Federal Regulations, 2011 CFR

2011-01-01

... inspection, time and place; application for approval of facilities as official import inspection... § 327.6 Products for importation; program inspection, time and place; application for approval of..., wholesome, and otherwise not adulterated at the time the products are offered for importation into the...

9 CFR 327.6 - Products for importation; program inspection, time and place; application for approval of...

Code of Federal Regulations, 2012 CFR

2012-01-01

... inspection, time and place; application for approval of facilities as official import inspection... § 327.6 Products for importation; program inspection, time and place; application for approval of..., wholesome, and otherwise not adulterated at the time the products are offered for importation into the...

9 CFR 327.6 - Products for importation; program inspection, time and place; application for approval of...

Code of Federal Regulations, 2014 CFR

2014-01-01

... inspection, time and place; application for approval of facilities as official import inspection... § 327.6 Products for importation; program inspection, time and place; application for approval of..., wholesome, and otherwise not adulterated at the time the products are offered for importation into the...

9 CFR 327.6 - Products for importation; program inspection, time and place; application for approval of...

Code of Federal Regulations, 2013 CFR

2013-01-01

... inspection, time and place; application for approval of facilities as official import inspection... § 327.6 Products for importation; program inspection, time and place; application for approval of..., wholesome, and otherwise not adulterated at the time the products are offered for importation into the...

Grade pending: lessons for hospital quality reporting from the New York City restaurant sanitation inspection program.

PubMed

Ryan, Andrew M; Detsky, Allan S

2015-02-01

Public quality reporting programs have been widely implemented in hospitals in an effort to improve quality and safety. One such program is Hospital Compare, Medicare's national quality reporting program for US hospitals. The New York City sanitary grade inspection program is a parallel effort for restaurants. The aims of Hospital Compare and the New York City sanitary inspection program are fundamentally similar: to address a common market failure resulting from consumers' lack of information on quality and safety. However, by displaying easily understandable information at the point of service, the New York City sanitary inspection program is better designed to encourage informed consumer decision making. We argue that this program holds important lessons for public quality reporting of US hospitals. © 2014 Society of Hospital Medicine.

Computed Tomography Inspection and Analysis for Additive Manufacturing Components

NASA Technical Reports Server (NTRS)

Beshears, Ronald D.

2017-01-01

Computed tomography (CT) inspection was performed on test articles additively manufactured from metallic materials. Metallic AM and machined wrought alloy test articles with programmed flaws and geometric features were inspected using a 2-megavolt linear accelerator based CT system. Performance of CT inspection on identically configured wrought and AM components and programmed flaws was assessed to determine the impact of additive manufacturing on inspectability of objects with complex geometries.

14 CFR 125.247 - Inspection programs and maintenance.

Code of Federal Regulations, 2014 CFR

2014-01-01

... CAPACITY OF 6,000 POUNDS OR MORE; AND RULES GOVERNING PERSONS ON BOARD SUCH AIRCRAFT Maintenance § 125.247 Inspection programs and maintenance. (a) No person may operate an airplane subject to this part unless (1... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Inspection programs and maintenance. 125...

14 CFR 125.247 - Inspection programs and maintenance.

Code of Federal Regulations, 2010 CFR

2010-01-01

... CAPACITY OF 6,000 POUNDS OR MORE; AND RULES GOVERNING PERSONS ON BOARD SUCH AIRCRAFT Maintenance § 125.247 Inspection programs and maintenance. (a) No person may operate an airplane subject to this part unless (1... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Inspection programs and maintenance. 125...

14 CFR 125.247 - Inspection programs and maintenance.

Code of Federal Regulations, 2011 CFR

2011-01-01

... CAPACITY OF 6,000 POUNDS OR MORE; AND RULES GOVERNING PERSONS ON BOARD SUCH AIRCRAFT Maintenance § 125.247 Inspection programs and maintenance. (a) No person may operate an airplane subject to this part unless (1... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Inspection programs and maintenance. 125...

14 CFR 125.247 - Inspection programs and maintenance.

Code of Federal Regulations, 2013 CFR

2013-01-01

... CAPACITY OF 6,000 POUNDS OR MORE; AND RULES GOVERNING PERSONS ON BOARD SUCH AIRCRAFT Maintenance § 125.247 Inspection programs and maintenance. (a) No person may operate an airplane subject to this part unless (1... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Inspection programs and maintenance. 125...

14 CFR 125.247 - Inspection programs and maintenance.

Code of Federal Regulations, 2012 CFR

2012-01-01

... CAPACITY OF 6,000 POUNDS OR MORE; AND RULES GOVERNING PERSONS ON BOARD SUCH AIRCRAFT Maintenance § 125.247 Inspection programs and maintenance. (a) No person may operate an airplane subject to this part unless (1... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Inspection programs and maintenance. 125...

76 FR 81360 - Cooperative Inspection Programs: Interstate Shipment of Meat and Poultry Products; Correction

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-28

.... FSIS-2008-0039] RIN 0583-AD37 Cooperative Inspection Programs: Interstate Shipment of Meat and Poultry... to ship meat and poultry products in interstate commerce. The final rule was published in the Federal... the Federal Register, the final rule, ``Cooperative Inspection Programs; Interstate Shipment of Meat...

Symbol interval optimization for molecular communication with drift.

PubMed

Kim, Na-Rae; Eckford, Andrew W; Chae, Chan-Byoung

2014-09-01

In this paper, we propose a symbol interval optimization algorithm in molecular communication with drift. Proper symbol intervals are important in practical communication systems since information needs to be sent as fast as possible with low error rates. There is a trade-off, however, between symbol intervals and inter-symbol interference (ISI) from Brownian motion. Thus, we find proper symbol interval values considering the ISI inside two kinds of blood vessels, and also suggest no ISI system for strong drift models. Finally, an isomer-based molecule shift keying (IMoSK) is applied to calculate achievable data transmission rates (achievable rates, hereafter). Normalized achievable rates are also obtained and compared in one-symbol ISI and no ISI systems.

Cross-modal transfer of the conditioned eyeblink response during interstimulus interval discrimination training in young rats

PubMed Central

Brown, Kevin L.; Stanton, Mark E.

2008-01-01

Eyeblink classical conditioning (EBC) was observed across a broad developmental period with tasks utilizing two interstimulus intervals (ISIs). In ISI discrimination, two distinct conditioned stimuli (CSs; light and tone) are reinforced with a periocular shock unconditioned stimulus (US) at two different CS-US intervals. Temporal uncertainty is identical in design with the exception that the same CS is presented at both intervals. Developmental changes in conditioning have been reported in each task beyond ages when single-ISI learning is well developed. The present study sought to replicate and extend these previous findings by testing each task at four separate ages. Consistent with previous findings, younger rats (postnatal day – PD - 23 and 30) trained in ISI discrimination showed evidence of enhanced cross-modal influence of the short CS-US pairing upon long CS conditioning relative to older subjects. ISI discrimination training at PD43-47 yielded outcomes similar to those in adults (PD65-71). Cross-modal transfer effects in this task therefore appear to diminish between PD30 and PD43-47. Comparisons of ISI discrimination with temporal uncertainty indicated that cross-modal transfer in ISI discrimination at the youngest ages did not represent complete generalization across CSs. ISI discrimination undergoes a more protracted developmental emergence than single-cue EBC and may be a more sensitive indicator of developmental disorders involving cerebellar dysfunction. PMID:18726989

Effects of interstimulus intervals on behavioral, heart rate, and event-related potential indices of infant engagement and sustained attention

PubMed Central

Xie, Wanze; Richards, John E.

2016-01-01

Maximizing infant attention to stimulus presentation during an EEG or ERP experiment is important for making valid inferences about the neural correlates of infant cognition. The present study examined the effects of stimulus presentation interstimulus interval (ISI) on behavioral and physiological indices of infant attention including infants’ fixation to visual presentation, the amount of heart rate (HR) change during sustained attention, and ERP components. This study compared an ISI that is typically used in infant EEG/ERP studies (e.g., 1,500–2,000 ms) with two shorter durations (400–600 ms and 600–1,000 ms). Thirty-six infants were tested cross-sectionally at 3, 4.5, and 6 months. It was found that using the short (400–600 ms) and medium (600–1,000 ms) ISIs resulted in more visually fixated trials and reduced frequency of fixation disengagement per experimental block. We also found larger HR changes during sustained attention to both of the shorter ISIs compared with the long ISI, and larger ERP responses when using the medium ISI compared to using the short and long ISIs. These data suggest that utilizing an optimal ISI (e.g., 600– 1,000 ms), which increases the presentation complexity and provides sufficient time for information processing, can promote infant engagement and sustained attention during stimulus presentation. PMID:27159263

Integrated Science Investigation of the Sun (ISIS): Design of the Energetic Particle Investigation

NASA Technical Reports Server (NTRS)

McComas, D. J.; Alexander, N.; Angold, N.; Bale, S.; Beebe, C.; Birdwell, B.; Boyle, M.; Burgum, J. M.; Burnham, J. A.; Christian, E. R.;

International collaborative study for the calibration of proposed International Standards for thromboplastin, rabbit, plain, and for thromboplastin, recombinant, human, plain.

PubMed

van den Besselaar, A M H P; Chantarangkul, V; Angeloni, F; Binder, N B; Byrne, M; Dauer, R; Gudmundsdottir, B R; Jespersen, J; Kitchen, S; Legnani, C; Lindahl, T L; Manning, R A; Martinuzzo, M; Panes, O; Pengo, V; Riddell, A; Subramanian, S; Szederjesi, A; Tantanate, C; Herbel, P; Tripodi, A

2018-01-01

Essentials Two candidate International Standards for thromboplastin (coded RBT/16 and rTF/16) are proposed. International Sensitivity Index (ISI) of proposed standards was assessed in a 20-centre study. The mean ISI for RBT/16 was 1.21 with a between-centre coefficient of variation of 4.6%. The mean ISI for rTF/16 was 1.11 with a between-centre coefficient of variation of 5.7%. Background The availability of International Standards for thromboplastin is essential for the calibration of routine reagents and hence the calculation of the International Normalized Ratio (INR). Stocks of the current Fourth International Standards are running low. Candidate replacement materials have been prepared. This article describes the calibration of the proposed Fifth International Standards for thromboplastin, rabbit, plain (coded RBT/16) and for thromboplastin, recombinant, human, plain (coded rTF/16). Methods An international collaborative study was carried out for the assignment of International Sensitivity Indexes (ISIs) to the candidate materials, according to the World Health Organization (WHO) guidelines for thromboplastins and plasma used to control oral anticoagulant therapy with vitamin K antagonists. Results Results were obtained from 20 laboratories. In several cases, deviations from the ISI calibration model were observed, but the average INR deviation attributabled to the model was not greater than 10%. Only valid ISI assessments were used to calculate the mean ISI for each candidate. The mean ISI for RBT/16 was 1.21 (between-laboratory coefficient of variation [CV]: 4.6%), and the mean ISI for rTF/16 was 1.11 (between-laboratory CV: 5.7%). Conclusions The between-laboratory variation of the ISI for candidate material RBT/16 was similar to that of the Fourth International Standard (RBT/05), and the between-laboratory variation of the ISI for candidate material rTF/16 was slightly higher than that of the Fourth International Standard (rTF/09). The candidate materials have been accepted by WHO as the Fifth International Standards for thromboplastin, rabbit plain, and thromboplastin, recombinant, human, plain. © 2017 International Society on Thrombosis and Haemostasis.

Integrated Science Investigation of the Sun (ISIS): Design of the Energetic Particle Investigation

NASA Astrophysics Data System (ADS)

McComas, D. J.; Alexander, N.; Angold, N.; Bale, S.; Beebe, C.; Birdwell, B.; Boyle, M.; Burgum, J. M.; Burnham, J. A.; Christian, E. R.; Cook, W. R.; Cooper, S. A.; Cummings, A. C.; Davis, A. J.; Desai, M. I.; Dickinson, J.; Dirks, G.; Do, D. H.; Fox, N.; Giacalone, J.; Gold, R. E.; Gurnee, R. S.; Hayes, J. R.; Hill, M. E.; Kasper, J. C.; Kecman, B.; Klemic, J.; Krimigis, S. M.; Labrador, A. W.; Layman, R. S.; Leske, R. A.; Livi, S.; Matthaeus, W. H.; McNutt, R. L.; Mewaldt, R. A.; Mitchell, D. G.; Nelson, K. S.; Parker, C.; Rankin, J. S.; Roelof, E. C.; Schwadron, N. A.; Seifert, H.; Shuman, S.; Stokes, M. R.; Stone, E. C.; Vandegriff, J. D.; Velli, M.; von Rosenvinge, T. T.; Weidner, S. E.; Wiedenbeck, M. E.; Wilson, P.

2016-12-01

The Integrated Science Investigation of the Sun (ISIS) is a complete science investigation on the Solar Probe Plus (SPP) mission, which flies to within nine solar radii of the Sun's surface. ISIS comprises a two-instrument suite to measure energetic particles over a very broad energy range, as well as coordinated management, science operations, data processing, and scientific analysis. Together, ISIS observations allow us to explore the mechanisms of energetic particles dynamics, including their: (1) Origins—defining the seed populations and physical conditions necessary for energetic particle acceleration; (2) Acceleration—determining the roles of shocks, reconnection, waves, and turbulence in accelerating energetic particles; and (3) Transport—revealing how energetic particles propagate from the corona out into the heliosphere. The two ISIS Energetic Particle Instruments measure lower (EPI-Lo) and higher (EPI-Hi) energy particles. EPI-Lo measures ions and ion composition from ˜20 keV/nucleon-15 MeV total energy and electrons from ˜25-1000 keV. EPI-Hi measures ions from ˜1-200 MeV/nucleon and electrons from ˜0.5-6 MeV. EPI-Lo comprises 80 tiny apertures with fields-of-view (FOVs) that sample over nearly a complete hemisphere, while EPI-Hi combines three telescopes that together provide five large-FOV apertures. ISIS observes continuously inside of 0.25 AU with a high data collection rate and burst data (EPI-Lo) coordinated with the rest of the SPP payload; outside of 0.25 AU, ISIS runs in low-rate science mode whenever feasible to capture as complete a record as possible of the solar energetic particle environment and provide calibration and continuity for measurements closer in to the Sun. The ISIS Science Operations Center plans and executes commanding, receives and analyzes all ISIS data, and coordinates science observations and analyses with the rest of the SPP science investigations. Together, ISIS' unique observations on SPP will enable the discovery, untangling, and understanding of the important physical processes that govern energetic particles in the innermost regions of our heliosphere, for the first time. This paper summarizes the ISIS investigation at the time of the SPP mission Preliminary Design Review in January 2014.

Level of Service Program for INDOT Operations : APPENDIX D Deficiency Score Index

DOT National Transportation Integrated Search

2012-01-01

INDOT has used an inspection program named Maintenance Quality Survey (MQS) to perform a statewide inspection of their roadway assets, rightofway to rightofway. This inspection requires two twoperson teams approximately 18 months to...

Level of Service Program for INDOT Operations : APPENDIX E Activity Defect Assignment

DOT National Transportation Integrated Search

2012-01-01

INDOT has used an inspection program named Maintenance Quality Survey (MQS) to perform a statewide inspection of their roadway assets, rightofway to rightofway. This inspection requires two twoperson teams approximately 18 months to...

Fault-Tolerant Control For A Robotic Inspection System

NASA Technical Reports Server (NTRS)

Tso, Kam Sing

1995-01-01

Report describes first phase of continuing program of research on fault-tolerant control subsystem of telerobotic visual-inspection system. Goal of program to develop robotic system for remotely controlled visual inspection of structures in outer space.

Computed Tomography Inspection and Analysis for Additive Manufacturing Components

NASA Technical Reports Server (NTRS)

Beshears, Ronald D.

2016-01-01

Computed tomography (CT) inspection was performed on test articles additively manufactured from metallic materials. Metallic AM and machined wrought alloy test articles with programmed flaws were inspected using a 2MeV linear accelerator based CT system. Performance of CT inspection on identically configured wrought and AM components and programmed flaws was assessed using standard image analysis techniques to determine the impact of additive manufacturing on inspectability of objects with complex geometries.

9 CFR 592.95 - Facilities and equipment to be furnished for use of inspection program personnel in performing...

Code of Federal Regulations, 2010 CFR

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Facilities and equipment to be furnished for use of inspection program personnel in performing service. 592.95 Section 592.95 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION...

Department of Defense counterdrug technology development of non-intrusive inspection systems

NASA Astrophysics Data System (ADS)

Pennella, John J.

1997-02-01

The Naval Surface Warfare Center Dahlgren Division serves as the executive agent for the DoD's Contraband Detection and Cargo Container Inspection Technology Development Program. The goal of the DoD non-intrusive inspection (NII) program is to develop prototype equipment that can be used to inspect containers and vehicles, quickly and in large numbers without unnecessary delays in the movement of legitimate cargo. This paper summaries the past accomplishments of the program, current status, and future plans.

9 CFR 592.90 - Authority and duties of inspection program personnel performing service.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Authority and duties of inspection program personnel performing service. 592.90 Section 592.90 Animals and Animal Products FOOD SAFETY AND..., certificates, seals, and reports of inspection program personnel; (4) To deface or remove, or cause to be...

9 CFR 592.90 - Authority and duties of inspection program personnel performing service.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Authority and duties of inspection program personnel performing service. 592.90 Section 592.90 Animals and Animal Products FOOD SAFETY AND..., certificates, seals, and reports of inspection program personnel; (4) To deface or remove, or cause to be...

Level of Service Program for INDOT Operations : APPENDIX B Sub-District Sample Sizes

DOT National Transportation Integrated Search

2012-01-01

INDOT has used an inspection program named Maintenance Quality Survey (MQS) to perform a statewide inspection of their roadway assets, rightofway to rightofway. This inspection requires two twoperson teams approximately 18 months to...

Level of Service Program for INDOT Operations : APPENDIX F Asset Deficiency Weight Scale

DOT National Transportation Integrated Search

2012-01-01

INDOT has used an inspection program named Maintenance Quality Survey (MQS) to perform a statewide inspection of their roadway assets, rightofway to rightofway. This inspection requires two twoperson teams approximately 18 months to...

The Isis project: Fault-tolerance in large distributed systems

NASA Technical Reports Server (NTRS)

Birman, Kenneth P.; Marzullo, Keith

1993-01-01

This final status report covers activities of the Isis project during the first half of 1992. During the report period, the Isis effort has achieved a major milestone in its effort to redesign and reimplement the Isis system using Mach and Chorus as target operating system environments. In addition, we completed a number of publications that address issues raised in our prior work; some of these have recently appeared in print, while others are now being considered for publication in a variety of journals and conferences.

The role of interstimulus interval and "Stimulus-type" in prepotent response inhibition abilities in people with ASD: A quantitative and qualitative review.

PubMed

Kuiper, Marieke W M; Verhoeven, Elisabeth W M; Geurts, Hilde M

2016-11-01

Autism spectrum disorders (ASD) are associated with prepotent response inhibition difficulties. However, the large variation between studies suggests that understudied factors, such as interstimulus interval (ISI) and "stimulus-type" (both hypothesized proxies of stressors influencing arousal), might influence the inhibitory abilities of people with ASD. Using meta-analysis, we tested whether differences in prepotent response inhibition between people with and without ASD was influenced by ISI. There was not enough variation in "stimulus-type" between the studies to include it as a moderator. Thirty-seven studies met inclusion criteria, with a combined sample size of 950 people with ASD and 966 typically developing controls. Additionally, a qualitative review including studies comparing a neutral and an arousing condition in one experiment was performed to examine whether fast ISI or specific arousing stimuli directly influence prepotent response inhibition. The meta-analysis indicated that ISI was not a relevant moderator. The qualitative review showed that ISI and "stimulus-type" had the same effect for both groups. Although all studies regarding ISI indicated that fast ISI worsened performance, different types of stimuli had either a positive or a negative influence. This could suggest that distinctive stimuli might affect arousal differently. While we replicated the inhibition difficulties in people with ASD (g = .51), our results do not show strong ASD-specific effects of ISI or "stimulus-type" on inhibition. Nonetheless, ISI and "stimulus-type" do seem to influence performance. Future research focusing on potential underlying factors (e.g., baseline physiological arousal) is needed to examine why this is the case. Autism Res 2016, 9: 1124-1141. © 2016 International Society for Autism Research, Wiley Periodicals, Inc. © 2016 International Society for Autism Research, Wiley Periodicals, Inc.

Distribution of Nonperfusion Area on Ultra-widefield Fluorescein Angiography in Eyes With Diabetic Macular Edema: DAVE Study.

PubMed

Fan, Wenying; Wang, Kang; Ghasemi Falavarjani, Khalil; Sagong, Min; Uji, Akihito; Ip, Michael; Wykoff, Charles C; Brown, David M; van Hemert, Jano; Sadda, SriniVas R

2017-08-01

To explore the distribution of nonperfusion area (NPA) in eyes with diabetic macular edema (DME) and its relationship with the severity of DME. Prospective, observational case series. Forty eyes of 29 patients with treatment-naïve DME who participated in the DAVE study (NCT01552408) were included. Ultra-widefield fluorescein angiography images were sent to the Doheny Image Reading Center, where they were montaged and corrected using stereographic projection to adjust for peripheral distortion. Two experienced, independent/masked certified graders manually segmented the NPA and the total visible retinal area (TRA), and computed the NPA and TRA in square millimeters (mm 2 ). The ischemic index (ISI) was calculated. The distributions of NPA and ISI within different retinal zones were correlated with the severity of DME. In 40 eyes with treatment-naïve DME (mean age, 55.8 years) visual acuity (VA) (mean 59.6 EDTRS letters) was correlated with central macular thickness (CMT) (mean 536.9 μm, R = -0.418, P = .008) and macular volume (MV) (mean 11.9 mm 3 , R = -0.449, P = .004). The NPA and ISI among the different retinal zones were significantly different (NPA: P < .001; ISI: P = .005). The NPA and ISI in the midperiphery were negatively associated with CMT (NPA: P = .04; ISI: P = .02). However, the global NPA and ISI for the entire retina were not associated with CMT or MV (P > .05). In eyes with DME, the ISI increases with increasing distance from the fovea. The severity of DME does not appear to correlate with global NPA and ISI. Copyright © 2017 Elsevier Inc. All rights reserved.

Plasma protein binding of an antisense oligonucleotide targeting human ICAM-1 (ISIS 2302).

PubMed

Watanabe, Tanya A; Geary, Richard S; Levin, Arthur A

2006-01-01

In vitro ultrafiltration was used to determine the plasma protein-binding characteristics of phosphorothioate oligonucleotides (PS ODNs). Although there are binding data on multiple PS ODNs presented here, the focus of this research is on the protein-binding characteristics of ISIS 2302, a PS ODN targeting human intercellular adhesion molecule-1 (ICAM-1) mRNA, which is currently in clinical trials for the treatment of ulcerative colitis. ISIS 2302 was shown to be highly bound (> 97%) across species (mouse, rat, monkey, human), with the mouse having the least degree of binding. ISIS 2302 was highly bound to albumin and, to a lesser, extent alpha2-macroglobulin and had negligible binding to alpha1-acid glycoprotein. Ten shortened ODN metabolites (8, 10, and 12-19 nucleotides [nt] in length, truncated from the 3' end) were evaluated in human plasma. The degree of binding was reduced as the ODN metabolite length decreased. Three additional 20-nt (20-mer) PS ODNs (ISIS 3521, ISIS 2503, and ISIS 5132) of varying sequence but similar chemistry were evaluated. Although the tested PS ODNs were highly bound to plasma proteins, suggesting a commonality within the chemical class, these results suggested that the protein-binding characteristics in human plasma may be sequence dependent. Lastly, drug displacement studies with ISIS 2302 and other concomitant drugs with known protein-binding properties were conducted to provide information on potential drug interactions. Coadministered ISIS 2302 and other high-binding drugs evaluated in this study did not displace one another at supraclinical plasma concentrations and, thus, are not anticipated to cause any pharmacokinetic interaction in the clinic as a result of the displacement of binding to plasma proteins.

A novel photosynthetic strategy for adaptation to low-iron aquatic environments

USGS Publications Warehouse

Chauhan, D.; Folea, I.M.; Jolley, C.C.; Kouril, R.; Lubner, C.E.; Lin, S.; Kolber, D.; Wolfe-Simon, Felisa; Golbeck, J.H.; Boekema, E.J.; Fromme, P.

2011-01-01

Iron (Fe) availability is a major limiting factor for primary production in aquatic environments. Cyanobacteria respond to Fe deficiency by derepressing the isiAB operon, which encodes the antenna protein IsiA and flavodoxin. At nanomolar Fe concentrations, a PSI-IsiA supercomplex forms, comprising a PSI trimer encircled by two complete IsiA rings. This PSI-IsiA supercomplex is the largest photosynthetic membrane protein complex yet isolated. This study presents a detailed characterization of this complex using transmission electron microscopy and ultrafast fluorescence spectroscopy. Excitation trapping and electron transfer are highly efficient, allowing cyanobacteria to avoid oxidative stress. This mechanism may be a major factor used by cyanobacteria to successfully adapt to modern low-Fe environments. ?? 2010 American Chemical Society.

Relationship between insulin sensitivity index and cognitive function in diet-induced insulin resistant rats.

PubMed

Chen, Sisi; Xie, Hao; Wu, Jing; Hong, Hao; Jin, Jianwen; Fang, Jinbo; Huang, Ji; Fu, Ying Zhou; Ji, Hui; Li, Yong Qi; Long, Yan; Xia, Yuan Zheng

2009-06-01

Clinical and animal studies have revealed significant cognitive impairment in type II diabetic subjects. However, whether there is a relationship between insulin resistance and cognitive function is poorly understood. In the present study, we used a high fat diet to induce insulin resistance (IR) in rats, insulin sensitivity index (ISI) (= FINS x FPG/22.5) to assess the extent of insulin resistance and the Morris Water Maze Task to judge cognitive function. The relationship between insulin sensitivity index and cognitive function was determined by analysing the correlation between ISI and the time rat spent in targeted quadrant, as well as between ISI and the times the rat swam across the very point where a platform was previously placed, using Pearson's method. Perfect negative correlation between ISI and cognitive function existed when ISI fell within a certain range, which indicates that insulin resistance is associated with cognitive function impairment in some cases where ISI might be an indicator.

High-Latitude Topside Ionospheric Vertical Electron-Density-Profile Changes in Response to Large Magnetic Storms

NASA Technical Reports Server (NTRS)

Benson, Robert F.; Fainberg, Joseph; Osherovich, Vladimir A.; Truhlik, Vladimir; Wang, Yongli; Bilitza, Dieter; Fung, Shing F.

2015-01-01

Large magnetic-storm induced changes have been detected in high-latitude topside vertical electron-density profiles Ne(h). The investigation was based on the large database of topside Ne(h) profiles and digital topside ionograms from the International Satellites for Ionospheric Studies (ISIS) program available from the NASA Space Physics Data Facility (SPDF) at http://spdf.gsfc.nasa.gov/isis/isis-status.html. This large database enabled Ne(h) profiles to be obtained when an ISIS satellite passed through nearly the same region of space before, during, and after a major magnetic storm. A major goal was to relate the magnetic-storm induced high-latitude Ne(h) profile changes to solar-wind parameters. Thus an additional data constraint was to consider only storms where solar-wind data were available from the NASA/SPDF OMNIWeb database. Ten large magnetic storms (with Dst less than -100 nT) were identified that satisfied both the Ne(h) profile and the solar-wind data constraints. During five of these storms topside ionospheric Ne(h) profiles were available in the high-latitude northern hemisphere and during the other five storms similar ionospheric data were available in the southern hemisphere. Large Ne(h) changes were observed during each one of these storms. Our concentration in this paper is on the northern hemisphere. The data coverage was best for the northern-hemisphere winter. Here Ne(h) profile enhancements were always observed when the magnetic local time (MLT) was between 00 and 03 and Ne(h) profile depletions were always observed between 08 and 10 MLT. The observed Ne(h) deviations were compared with solar-wind parameters, with appropriate time shifts, for four storms.

Results of calendar year 1994 monitor well inspection and maintenance program, Y-12 Plant, Oak Ridge, Tennessee

DOE Office of Scientific and Technical Information (OSTI.GOV)

McMaster, B.W.; Jones, S.B.; Sitzler, J.L.

1995-06-01

This document is a compendium of results of the calendar year 1994 Monitor Well Inspection and Maintenance Program at the Department of Energy Y-12 Plant in Oak Ridge, Tennessee. This report documents the work relating to well inspections and maintenance requests. Inspections are implemented in order to better assess the condition and maintenance needs of wells that are actively being monitored. Currently this approach calls for inspecting all wells on a routine (annual or triennial) basis which are: (1) in an active sampling program; (2) included in a hydrologic study; or (3) not in service, but not scheduled for pluggingmore » and abandonment. Routine inspections help to ensure that representative groundwater samples and hydrologic data are being collected, and contribute to the life expectancy of each well. This report formally presents well inspection and maintenance activities that were conducted at the Y-12 Plant during 1994. All inspections were conducted between April and December.« less

Molecular characterization and genomic distribution of Isis: a new retrotransposon of Drosophila buzzatii.

PubMed

García Guerreiro, M P; Fontdevila, A

2007-01-01

A new transposable element, Isis, is identified as a LTR retrotransposon in Drosophila buzzatii. DNA sequence analysis shows that Isis contains three long ORFs similar to gag, pol and env genes of retroviruses. The ORF1 exhibits sequence homology to matrix, capsid and nucleocapsid gag proteins and ORF2 encodes a putative protease (PR), a reverse transcriptase (RT), an Rnase H (RH) and an integrase (IN) region. The analysis of a putative env product, encoded by the env ORF3, shows a degenerated protein containing several stop codons. The molecular study of the putative proteins coded by this new element shows striking similarities to both Ulysses and Osvaldo elements, two LTR retrotransposons, present in D. virilis and D. buzzatii, respectively. Comparisons of the predicted Isis RT to several known retrotransposons show strong phylogenetic relationships to gypsy-like elements, particulary to Ulysses retrotransposon. Studies of Isis chromosomal distribution show a strong hybridization signal in centromeric and pericentromeric regions, and a scattered distribution along all chromosomal arms. The existence of insertional polymorphisms between different strains and high molecular weight bands by Southern blot suggests the existence of full-sized copies that have been active recently. The presence of euchromatic insertion sites coincident between Isis and Osvaldo could indicate preferential insertion sites of Osvaldo element into Isis sequence or vice versa. Moreover, the presence of Isis in different species of the buzzatii complex indicates the ancient origin of this element.

Evaluation on the Feasibility of Using Ultrasonic Testing of Reactor Pressure Vessel Welds for Assessing Flaw Density/Distribution per 10 CFR 50.61a, Alternate Fracture Toughness Requirements for Protection Against Pressurized Thermal Shock

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sullivan, Edmund J.; Anderson, Michael T.

2014-06-10

This technical letter report provides the status of an assessment undertaken by PNNL at the request of the NRC to verify the capability of periodic ASME-required volumetric examinations of reactor vessels to characterize the density and distribution of flaws of interest for applying §50.61a on a plant-by-plant basis. The PTS rule, described in the Code of Federal Regulations, Title 10, Section 50.61 (§50.61), "Fracture Toughness Requirements for Protection against Pressurized Thermal Shock Events," establishes screening criteria to ensure that the potential for a reactor vessel to fail due to a PTS event is deemed to be acceptably low. Recently, themore » NRC completed a research program that concluded that the risk of through-wall cracking due to a PTS event is much lower than previously estimated. The NRC subsequently developed and promulgated an alternate PTS rule, §50.61a, that can be implemented by PWR licensees. The §50.61a rule differs from §50.61 in that it requires licensees who choose to follow this alternate method to analyze the results from periodic volumetric examinations required by the ASME Code, Section XI, Rules for Inservice Inspection (ISI) of Nuclear Power Plants.« less

A management system for evaluating the Virginia periodic motor vehicle inspection program.

DOT National Transportation Integrated Search

1977-01-01

A system for management evaluation of Virginia's periodic motor vehicle inspection (PMVI) program was developed which is similar to that currently in use by the Virginia Department of State Police, except for changes in the sample size of inspection ...

Leveraging ISI Multi-Model Prediction for Navy Operations: Proposal to the Office of Naval Research

DTIC Science & Technology

2013-09-30

Operations: Proposal to the Office of Naval Research” PI: Benjamin Kirtman University of Miami – RSMAS Meteorology and Physical Oceanography...Prediction for Navy Operations: Proposal to the Office of Naval Research 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d

National Program for Inspection of Non-Federal Dams. Spectacle Swamp Dam (CT 00476), Connecticut Coastal Basin, Wilton, Connecticut. Phase I Inspection Report.

DTIC Science & Technology

1981-05-01

CT 00476 IA 𔄁V 7 4. TITLE (nd $ba#ile) S. TYPE OF REPORT a PERIOD COVERED Spectacle Swamp Dam INSPECTION REPORT NATIONAL PROGRAM FOR INSPECTION OF...PERFORMING ORGANIZATION NAME AND ADDRESS 10. PROGRAM ELrihENT. PROJECT. TASK AREA & WORK UNIT NUMS1RS X 1I. CONTROLLING OFFICE NAME AND ADDRESS Ia ...SCNEDULE 16. DISTRIOUTION STATEMENT (1 tklReport) APPROVAL FOR PUBLIC RELEASE: DISTRIBUTION UNLIMITED 5 17. DISTRIOUTION STATEMENT (of IA * he r ieet

Mineralogical Mapping of Asteroid Itokawa using Calibrated Hayabusa AMICA images and NIRS Spectrometer Data

NASA Astrophysics Data System (ADS)

Le Corre, Lucille; Becker, Kris J.; Reddy, Vishnu; Li, Jian-Yang; Bhatt, Megha

2016-10-01

The goal of our work is to restore data from the Hayabusa spacecraft that is available in the Planetary Data System (PDS) Small Bodies Node. More specifically, our objectives are to radiometrically calibrate and photometrically correct AMICA (Asteroid Multi-Band Imaging Camera) images of Itokawa. The existing images archived in the PDS are not in reflectance and not corrected from the effect of viewing geometry. AMICA images are processed with the Integrated Software for Imagers and Spectrometers (ISIS) system from USGS, widely used for planetary image analysis. The processing consists in the ingestion of the images in ISIS (amica2isis), updates to AMICA start time (sumspice), radiometric calibration (amicacal) including smear correction, applying SPICE ephemeris, adjusting control using Gaskell SUMFILEs (sumspice), projecting individual images (cam2map) and creating global or local mosaics. The application amicacal has also an option to remove pixels corresponding to the polarizing filters on the left side of the image frame. The amicacal application will include a correction for the Point Spread Function. The last version of the PSF published by Ishiguro et al. in 2014 includes correction for the effect of scattered light. This effect is important to correct because it can add 10% level in error and is affecting mostly the longer wavelength filters such as zs and p. The Hayabusa team decided to use the color data for six of the filters for scientific analysis after correcting for the scattered light. We will present calibrated data in I/F for all seven AMICA color filters. All newly implemented ISIS applications and map projections from this work have been or will be distributed to the community via ISIS public releases. We also processed the NIRS spectrometer data, and we will perform photometric modeling, then apply photometric corrections, and finally extract mineralogical parameters. The end results will be the creation of pyroxene chemistry and olivine/pyroxene ratio maps of Itokawa using NIRS and AMICA map products. All the products from this work will be archived on the PDS website. This work was supported by NASA Planetary Missions Data Analysis Program grant NNX13AP27G.

Java Image I/O for VICAR, PDS, and ISIS

NASA Technical Reports Server (NTRS)

Deen, Robert G.; Levoe, Steven R.

2011-01-01

This library, written in Java, supports input and output of images and metadata (labels) in the VICAR, PDS image, and ISIS-2 and ISIS-3 file formats. Three levels of access exist. The first level comprises the low-level, direct access to the file. This allows an application to read and write specific image tiles, lines, or pixels and to manipulate the label data directly. This layer is analogous to the C-language "VICAR Run-Time Library" (RTL), which is the image I/O library for the (C/C++/Fortran) VICAR image processing system from JPL MIPL (Multimission Image Processing Lab). This low-level library can also be used to read and write labeled, uncompressed images stored in formats similar to VICAR, such as ISIS-2 and -3, and a subset of PDS (image format). The second level of access involves two codecs based on Java Advanced Imaging (JAI) to provide access to VICAR and PDS images in a file-format-independent manner. JAI is supplied by Sun Microsystems as an extension to desktop Java, and has a number of codecs for formats such as GIF, TIFF, JPEG, etc. Although Sun has deprecated the codec mechanism (replaced by IIO), it is still used in many places. The VICAR and PDS codecs allow any program written using the JAI codec spec to use VICAR or PDS images automatically, with no specific knowledge of the VICAR or PDS formats. Support for metadata (labels) is included, but is format-dependent. The PDS codec, when processing PDS images with an embedded VIAR label ("dual-labeled images," such as used for MER), presents the VICAR label in a new way that is compatible with the VICAR codec. The third level of access involves VICAR, PDS, and ISIS Image I/O plugins. The Java core includes an "Image I/O" (IIO) package that is similar in concept to the JAI codec, but is newer and more capable. Applications written to the IIO specification can use any image format for which a plug-in exists, with no specific knowledge of the format itself.

Cargo container inspection test program at ARPA's Nonintrusive Inspection Technology Testbed

NASA Astrophysics Data System (ADS)

Volberding, Roy W.; Khan, Siraj M.

1994-10-01

An x-ray-based cargo inspection system test program is being conducted at the Advanced Research Project Agency (ARPA)-sponsored Nonintrusive Inspection Technology Testbed (NITT) located in the Port of Tacoma, Washington. The test program seeks to determine the performance that can be expected from a dual, high-energy x-ray cargo inspection system when inspecting ISO cargo containers. This paper describes an intensive, three-month, system test involving two independent test groups, one representing the criminal smuggling element and the other representing the law enforcement community. The first group, the `Red Team', prepares ISO containers for inspection at an off-site facility. An algorithm randomly selects and indicates the positions and preparation of cargoes within a container. The prepared container is dispatched to the NITT for inspection by the `Blue Team'. After in-gate processing, it is queued for examination. The Blue Team inspects the container and decides whether or not to pass the container. The shipment undergoes out-gate processing and returns to the Red Team. The results of the inspection are recorded for subsequent analysis. The test process, including its governing protocol, the cargoes, container preparation, the examination and results available at the time of submission are presented.

The Potential of Sonic IR to Inspect Aircraft Components Traditionally Inspected with Fluorescent Penetrant and or Magnetic Particle Inspection

NASA Astrophysics Data System (ADS)

DiMambro, J.; Ashbaugh, D. M.; Han, X.; Favro, L. D.; Lu, J.; Zeng, Z.; Li, W.; Newaz, G. M.; Thomas, R. L.

2006-03-01

Sandia National Laboratories Airworthiness Assurance Nondestructive Inspection Validation Center (AANC) provides independent and quantitative evaluations of new and enhanced inspection, to developers, users, and regulators of aircraft. Wayne State University (WSU) has developed and patented an inspection technique using high-power ultrasonic excitation and infrared technology to detect defects in a variety of materials. AANC and WSU are working together as part of the FAA Sonic Infrared Technology Transfer Program. The ultimate goal of the program is to implement Sonic IR in the aviation field where appropriate. The capability of Sonic IR imaging to detect cracks in components commonly inspected with magnetic particle or liquid penetrant inspection in the field is of interest to industry.

Mini-Micro CDS/ISIS in the Thailand Development Research Institute Library.

ERIC Educational Resources Information Center

Wongkoltoot, Poonsin; Indee, Somsak

1992-01-01

Describes the Thailand Development Research Institute Library's development of an integrated bibliographic system using UNESCO's Micro-ISIS software. Linkages between databases were made using an in-house application (TIBIS) written in CDS/ISIS Pascal. The library system is available on a local area network (LAN). (three references) (EA)

Decade of War: Applying Past Lessons to the Counter-ISIS Campaign

DTIC Science & Technology

2017-05-22

coalition partners to fight ISIS and its affiliates; (E) mechanisms to cut off or seize ISIS’s financial support, including financial transfers, money ... laundering , oil revenue, human trafficking, sales of looted art and historical artifacts, and other revenue sources; and (F) a detailed strategy to

Isis: Integrated Shape Imaging System (Oxford Metrics Ltd.) A New System For Follow-Up Of Scoliosis.

NASA Astrophysics Data System (ADS)

Van Poucke, M.; Boone, P.; Vercauteren, M.

1986-07-01

ISIS is a non-invasive optical method for obtaining topographical data of the human back shape. It is used for the follow-up of scoliosis (spinal deformity). Using the ISIS, the number of x-ray photographs can be reduced in the scoliosis clinics.

The Reasoning behind Informal Statistical Inference

ERIC Educational Resources Information Center

Makar, Katie; Bakker, Arthur; Ben-Zvi, Dani

2011-01-01

Informal statistical inference (ISI) has been a frequent focus of recent research in statistics education. Considering the role that context plays in developing ISI calls into question the need to be more explicit about the reasoning that underpins ISI. This paper uses educational literature on informal statistical inference and philosophical…

Coordinated ionospheric and magnetospheric observations from the ISIS 2 satellite by the ISIS 2 experimenters. Volume 2: Auroral optical emissions magnetic field perturbations, and plasma characteristics, measured simultaneously on the same magnetic field line

NASA Technical Reports Server (NTRS)

Shepherd, G. G.

1980-01-01

The data set consists of a selected number of passes, each comprising a format combination that is most appropriate for the particular data set. A list of ISIS 2 experimenters, with addresses and telephone numbers is included. A brief description of the ISIS 2 satellite is given, followed by more detailed instrument descriptions, format descriptions, data set descriptions, and the data themselves.

The process group approach to reliable distributed computing

NASA Technical Reports Server (NTRS)

Birman, Kenneth P.

1991-01-01

The difficulty of developing reliable distributed software is an impediment to applying distributed computing technology in many settings. Experience with the ISIS system suggests that a structured approach based on virtually synchronous process groups yields systems which are substantially easier to develop, fault-tolerance, and self-managing. Six years of research on ISIS are reviewed, describing the model, the types of applications to which ISIS was applied, and some of the reasoning that underlies a recent effort to redesign and reimplement ISIS as a much smaller, lightweight system.

Mipomersen.

PubMed

2010-01-01

Genzyme Corporation and Isis Pharmaceuticals have a worldwide licensing and collaboration agreement for the development of subcutaneous mipomersen (ISIS 147764; ISIS 301012; ISIS301012; mipomersen-sodium). Mipomersen, an oligonucleotide antisense inhibitor directed against apolipoprotein B-100 (apoB-100) mRNA, is in phase III clinical evaluation for the treatment of familial hypercholesterolemia, a form of type IIa hyperlipoproteinemia, and hypercholesterolemia in patients with severely high cholesterol levels or at high risk for coronary heart disease in the US, European Union, Brazil, Canada, South Africa, and South East Asia. This review discusses the development history and scientific profile of this new compound.

Validation of the insomnia severity index as a web-based measure.

PubMed

Thorndike, Frances P; Ritterband, Lee M; Saylor, Drew K; Magee, Joshua C; Gonder-Frederick, Linda A; Morin, Charles M

2011-01-01

Although the Insomnia Severity Index (ISI) is already administered online, this frequently used instrument has not been validated for Web delivery. This study compares online and paper-and-pencil ISI versions completed by participants in a randomized controlled trial testing an Internet-delivered intervention for insomnia. Forty-three adults with insomnia completed both ISI versions during pre- (Assessment 1) and post-intervention (Assessment 2). Correlations between total scores of both versions were significant (rs ≥ .98, ps < .001). For both ISI versions, internal consistency was acceptable (Assessment 1, α = .61; Assessment 2, α ≥ .88). Among participants not receiving the parent study intervention, correlations between 1 format at Assessment 1 and the alternative format at Assessment 2 were generally significant (rs = .26-.82). Together, findings suggest the ISI can be delivered online.

First graders' literacy and self-regulation gains: The effect of individualizing student instruction

PubMed Central

Connor, Carol McDonald; Ponitz, Claire Cameron; Phillips, Beth M.; Travis, Q. Monét; Glasney, Stephanie; Morrison, Frederick J.

2010-01-01

We examined the effect of individualizing student instruction (ISI; N=445 students, 46 classrooms) on first graders' self-regulation gains compared to a business-as-usual control group. Self-regulation, conceptualized as a constellation of executive skills, was positively associated with academic development. We hypothesized that the ISI intervention's emphasis on teacher planning and organization, classroom management, and the opportunity for students to work independently and in small groups would promote students' self-regulation. We found no main effect of ISI on self-regulation gains. However, for students with weaker initial self-regulation, ISI was associated with greater self-regulation gains compared to peers in control classrooms. The ISI effect on self-regulation was greater when the intervention was more fully implemented. PMID:20728691

Inverted stereocontrol of iridoid synthase in snapdragon.

PubMed

Kries, Hajo; Kellner, Franziska; Kamileen, Mohamed Omar; O'Connor, Sarah E

2017-09-01

The natural product class of iridoids, found in various species of flowering plants, harbors astonishing chemical complexity. The discovery of iridoid biosynthetic genes in the medicinal plant Catharanthus roseus has provided insight into the biosynthetic origins of this class of natural product. However, not all iridoids share the exact five- to six-bicyclic ring scaffold of the Catharanthus iridoids. For instance, iridoids in the ornamental flower snapdragon ( Antirrhinum majus , Plantaginaceae family) are derived from the C7 epimer of this scaffold. Here we have cloned and characterized the iridoid synthase enzyme from A. majus (AmISY), the enzyme that is responsible for converting 8-oxogeranial into the bicyclic iridoid scaffold in a two-step reduction-cyclization sequence. Chiral analysis of the reaction products reveals that AmISY reduces C7 to generate the opposite stereoconfiguration in comparison with the Catharanthus homologue CrISY. The catalytic activity of AmISY thus explains the biosynthesis of 7-epi-iridoids in Antirrhinum and related genera. However, although the stereoselectivity of the reduction step catalyzed by AmISY is clear, in both AmISY and CrISY, the cyclization step produces a diastereomeric mixture. Although the reduction of 8-oxogeranial is clearly enzymatically catalyzed, the cyclization step appears to be subject to less stringent enzyme control. © 2017 by The American Society for Biochemistry and Molecular Biology, Inc.

Inverted stereocontrol of iridoid synthase in snapdragon

PubMed Central

Kries, Hajo; Kellner, Franziska; Kamileen, Mohamed Omar; O'Connor, Sarah E.

2017-01-01

The natural product class of iridoids, found in various species of flowering plants, harbors astonishing chemical complexity. The discovery of iridoid biosynthetic genes in the medicinal plant Catharanthus roseus has provided insight into the biosynthetic origins of this class of natural product. However, not all iridoids share the exact five- to six-bicyclic ring scaffold of the Catharanthus iridoids. For instance, iridoids in the ornamental flower snapdragon (Antirrhinum majus, Plantaginaceae family) are derived from the C7 epimer of this scaffold. Here we have cloned and characterized the iridoid synthase enzyme from A. majus (AmISY), the enzyme that is responsible for converting 8-oxogeranial into the bicyclic iridoid scaffold in a two-step reduction–cyclization sequence. Chiral analysis of the reaction products reveals that AmISY reduces C7 to generate the opposite stereoconfiguration in comparison with the Catharanthus homologue CrISY. The catalytic activity of AmISY thus explains the biosynthesis of 7-epi-iridoids in Antirrhinum and related genera. However, although the stereoselectivity of the reduction step catalyzed by AmISY is clear, in both AmISY and CrISY, the cyclization step produces a diastereomeric mixture. Although the reduction of 8-oxogeranial is clearly enzymatically catalyzed, the cyclization step appears to be subject to less stringent enzyme control. PMID:28701463

Pharmacology of a Central Nervous System Delivered 2′-O-Methoxyethyl–Modified Survival of Motor Neuron Splicing Oligonucleotide in Mice and Nonhuman Primates

PubMed Central

Chun, Seung J.; Norris, Daniel A.; Hung, Gene; Lee, Sam; Matson, John; Fey, Robert A.; Gaus, Hans; Hua, Yimin; Grundy, John S.; Krainer, Adrian R.; Henry, Scott P.; Bennett, C. Frank

2014-01-01

Spinal muscular atrophy (SMA) is a debilitating neuromuscular disease caused by the loss of survival of motor neuron (SMN) protein. Previously, we demonstrated that ISIS 396443, an antisense oligonucleotide (ASO) targeted to the SMN2 pre-mRNA, is a potent inducer of SMN2 exon 7 inclusion and SMN protein expression, and improves function and survival of mild and severe SMA mouse models. Here, we demonstrate that ISIS 396443 is the most potent ASO in central nervous system (CNS) tissues of adult mice, compared with several other chemically modified ASOs. We evaluated methods of ISIS 396443 delivery to the CNS and characterized its pharmacokinetics and pharmacodynamics in rodents and nonhuman primates (NHPs). Intracerebroventricular bolus injection is a more efficient method of delivering ISIS 396443 to the CNS of rodents, compared with i.c.v. infusion. For both methods of delivery, the duration of ISIS 396443–mediated SMN2 splicing correction is long lasting, with maximal effects still observed 6 months after treatment discontinuation. Administration of ISIS 396443 to the CNS of NHPs by a single intrathecal bolus injection results in widespread distribution throughout the spinal cord. Based upon these preclinical studies, we have advanced ISIS 396443 into clinical development. PMID:24784568

Auditory Memory Decay as Reflected by a New Mismatch Negativity Score Is Associated with Episodic Memory in Older Adults at Risk of Dementia

PubMed Central

Laptinskaya, Daria; Thurm, Franka; Küster, Olivia C.; Fissler, Patrick; Schlee, Winfried; Kolassa, Stephan; von Arnim, Christine A. F.; Kolassa, Iris-Tatjana

2018-01-01

The auditory mismatch negativity (MMN) is an event-related potential (ERP) peaking about 100–250 ms after the onset of a deviant tone in a sequence of identical (standard) tones. Depending on the interstimulus interval (ISI) between standard and deviant tones, the MMN is suitable to investigate the pre-attentive auditory discrimination ability (short ISIs, ≤ 2 s) as well as the pre-attentive auditory memory trace (long ISIs, >2 s). However, current results regarding the MMN as an index for mild cognitive impairment (MCI) and dementia are mixed, especially after short ISIs: while the majority of studies report positive associations between the MMN and cognition, others fail to find such relationships. To elucidate these so far inconsistent results, we investigated the validity of the MMN as an index for cognitive impairment exploring the associations between different MMN indices and cognitive performance, more specifically with episodic memory performance which is among the most affected cognitive domains in the course of Alzheimer’s dementia (AD), at baseline and at a 5-year-follow-up. We assessed the amplitude of the MMN for short ISI (stimulus onset asynchrony, SOA = 0.05 s) and for long ISI (3 s) in a neuropsychologically well-characterized cohort of older adults at risk of dementia (subjective memory impairment, amnestic and non-amnestic MCI; n = 57). Furthermore, we created a novel difference score (ΔMMN), defined as the difference between MMNs to short and to long ISI, as a measure to assess the decay of the auditory memory trace, higher values indicating less decay. ΔMMN and MMN amplitude after long ISI, but not the MMN amplitude after short ISI, was associated with episodic memory at baseline (β = 0.38, p = 0.003; β = −0.27, p = 0.047, respectively). ΔMMN, but not the MMN for long ISIs, was positively associated with episodic memory performance at the 5-year-follow-up (β = 0.57, p = 0.013). The results suggest that the MMN after long ISI might be suitable as an indicator for the decline in episodic memory and indicate ΔMMN as a potential biomarker for memory impairment in older adults at risk of dementia. PMID:29456500

Auditory Memory Decay as Reflected by a New Mismatch Negativity Score Is Associated with Episodic Memory in Older Adults at Risk of Dementia.

PubMed

Laptinskaya, Daria; Thurm, Franka; Küster, Olivia C; Fissler, Patrick; Schlee, Winfried; Kolassa, Stephan; von Arnim, Christine A F; Kolassa, Iris-Tatjana

2018-01-01

The auditory mismatch negativity (MMN) is an event-related potential (ERP) peaking about 100-250 ms after the onset of a deviant tone in a sequence of identical (standard) tones. Depending on the interstimulus interval (ISI) between standard and deviant tones, the MMN is suitable to investigate the pre-attentive auditory discrimination ability (short ISIs, ≤ 2 s) as well as the pre-attentive auditory memory trace (long ISIs, >2 s). However, current results regarding the MMN as an index for mild cognitive impairment (MCI) and dementia are mixed, especially after short ISIs: while the majority of studies report positive associations between the MMN and cognition, others fail to find such relationships. To elucidate these so far inconsistent results, we investigated the validity of the MMN as an index for cognitive impairment exploring the associations between different MMN indices and cognitive performance, more specifically with episodic memory performance which is among the most affected cognitive domains in the course of Alzheimer's dementia (AD), at baseline and at a 5-year-follow-up. We assessed the amplitude of the MMN for short ISI (stimulus onset asynchrony, SOA = 0.05 s) and for long ISI (3 s) in a neuropsychologically well-characterized cohort of older adults at risk of dementia (subjective memory impairment, amnestic and non-amnestic MCI; n = 57). Furthermore, we created a novel difference score (ΔMMN), defined as the difference between MMNs to short and to long ISI, as a measure to assess the decay of the auditory memory trace, higher values indicating less decay. ΔMMN and MMN amplitude after long ISI, but not the MMN amplitude after short ISI, was associated with episodic memory at baseline ( β = 0.38, p = 0.003; β = -0.27, p = 0.047, respectively). ΔMMN, but not the MMN for long ISIs, was positively associated with episodic memory performance at the 5-year-follow-up ( β = 0.57, p = 0.013). The results suggest that the MMN after long ISI might be suitable as an indicator for the decline in episodic memory and indicate ΔMMN as a potential biomarker for memory impairment in older adults at risk of dementia.

78 FR 23740 - Gypsy Moth Program; Record of Decision

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-22

... April 2013. Kevin Shea, Acting Administrator, Animal and Plant Health Inspection Service. [FR Doc. 2013... DEPARTMENT OF AGRICULTURE Animal and Plant Health Inspection Service [Docket No. APHIS-2012-0113] Gypsy Moth Program; Record of Decision AGENCY: Animal and Plant Health Inspection Service, USDA. ACTION...

Maryland motor carrier program performance enhancement : [research summary].

DOT National Transportation Integrated Search

2014-02-01

The Maryland Motor Carrier Program (MMCP) involves the regulation of : commercial vehicle safety inspections. This includes roadside inspections : programs which have a goal of improving safety and reducing crashes : involving commercial vehicles. Th...

Biodegradable injectable in situ implants and microparticles for sustained release of montelukast: in vitro release, pharmacokinetics, and stability.

PubMed

Ahmed, Tarek A; Ibrahim, Hany M; Samy, Ahmed M; Kaseem, Alaa; Nutan, Mohammad T H; Hussain, Muhammad Delwar

2014-06-01

The objective of this study was to investigate the sustained release of a hydrophilic drug, montelukast (MK), from two biodegradable polymeric drug delivery systems, in situ implant (ISI) and in situ microparticles (ISM). N-Methyl pyrrolidone (NMP), dimethyl sulfoxide (DMSO), triacetin, and ethyl acetate were selected as solvents. The release of 10% (w/v) MK from both systems containing poly-lactic-co-glycolic acid (PLGA) as the biodegradable polymer was compared. Upon contact with the aqueous medium, the PLGA in ISI and ISM systems solidified resulting in implants and microparticles, respectively. The in vitro drug release from the ISI system showed marked difference from miscible solvents (NMP and DMSO) than the partially miscible ones (triacetin and ethyl acetate), and the drug release decreased with increased PLGA concentration. In the ISM system, the initial in vitro drug release decreased with decreased ratio of polymer phase to external oil phase. In vivo studies in rats showed that ISM had slower drug release than the drug release from ISI. Also, the ISM system when compared to ISI system had significantly reduced initial burst effect. In vitro as well as the in vivo studies for both ISI and ISM systems showed sustained release of MK. The ISM system is suitable for sustained release of MK over 4-week period with a lower initial burst compared to the ISI system. Stability studies of the ISI and ISM formulations showed that MK is stable in the formulations stored at 4°C for more than 2 years.

Validation of the German version of the insomnia severity index in adolescents, young adults and adult workers: results from three cross-sectional studies.

PubMed

Gerber, Markus; Lang, Christin; Lemola, Sakari; Colledge, Flora; Kalak, Nadeem; Holsboer-Trachsler, Edith; Pühse, Uwe; Brand, Serge

2016-05-31

A variety of objective and subjective methods exist to assess insomnia. The Insomnia Severity Index (ISI) was developed to provide a brief self-report instrument useful to assess people's perception of sleep complaints. The ISI was developed in English, and has been translated into several languages including German. Surprisingly, the psychometric properties of the German version have not been evaluated, although the ISI is often used with German-speaking populations. The psychometric properties of the ISI are tested in three independent samples: 1475 adolescents, 862 university students, and 533 police and emergency response service officers. In all three studies, participants provide information about insomnia (ISI), sleep quality (Pittsburgh Sleep Quality Index), and psychological functioning (diverse instruments). Descriptive statistics, gender differences, homogeneity and internal consistency, convergent validity, and factorial validity (including measurement invariance across genders) are examined in each sample. The findings show that the German version of the ISI has generally acceptable psychometric properties and sufficient concurrent validity. Confirmatory factor analyses show that a 1-factor solution achieves good model fit. Furthermore, measurement invariance across gender is supported in all three samples. While the ISI has been widely used in German-speaking countries, this study is the first to provide empirical evidence that the German version of this instrument has good psychometric properties and satisfactory convergent and factorial validity across various age groups and both men and women. Thus, the German version of the ISI can be recommended as a brief screening measure in German-speaking populations.

Validating the cross-cultural factor structure and invariance property of the Insomnia Severity Index: evidence based on ordinal EFA and CFA.

PubMed

Chen, Po-Yi; Yang, Chien-Ming; Morin, Charles M

2015-05-01

The purpose of this study is to examine the factor structure of the Insomnia Severity Index (ISI) across samples recruited from different countries. We tried to identify the most appropriate factor model for the ISI and further examined the measurement invariance property of the ISI across samples from different countries. Our analyses included one data set collected from a Taiwanese sample and two data sets obtained from samples in Hong Kong and Canada. The data set collected in Taiwan was analyzed with ordinal exploratory factor analysis (EFA) to obtain the appropriate factor model for the ISI. After that, we conducted a series of confirmatory factor analyses (CFAs), which is a special case of the structural equation model (SEM) that concerns the parameters in the measurement model, to the statistics collected in Canada and Hong Kong. The purposes of these CFA were to cross-validate the result obtained from EFA and further examine the cross-cultural measurement invariance of the ISI. The three-factor model outperforms other models in terms of global fit indices in Taiwan's population. Its external validity is also supported by confirmatory factor analyses. Furthermore, the measurement invariance analyses show that the strong invariance property between the samples from different cultures holds, providing evidence that the ISI results obtained in different cultures are comparable. The factorial validity of the ISI is stable in different populations. More importantly, its invariance property across cultures suggests that the ISI is a valid measure of the insomnia severity construct across countries. Copyright © 2014 Elsevier B.V. All rights reserved.

National Dam Safety Program. Lake Muskoday Dam (Inventory Number N.Y. 341) Delaware River Basin, Sullivan County, New York. Phase I Inspection Report,

DTIC Science & Technology

1981-09-14

DACW-51-81-C-0006 . PERFORMING ORGANIZATION NAME AND ADDRESS 10. PROGRAM ELEMENT PROJECT. TASK AREA & WORK UNIT NUMBERS ~ Flaherty-Giauara Associates...olie It neceary and Idontily b block number) Dam Safety National Dam Safety Program Visual Inspection Lake Muskoday Dam Hydrology, Structural Stability...DELAWARE RIVER BASIN LAKE MUSKODAY DAM SULLIVAN COUNTY, NEW YORK INVENTORY No.NY341 PHASE I INSPECTION REPORT NATIONAL DAM SAFETY PROGRAM J T C NEW YORK

Post-earthquake building safety inspection: Lessons from the Canterbury, New Zealand, earthquakes

USGS Publications Warehouse

Marshall, J.; Jaiswal, Kishor; Gould, N.; Turner, F.; Lizundia, B.; Barnes, J.

2013-01-01

The authors discuss some of the unique aspects and lessons of the New Zealand post-earthquake building safety inspection program that was implemented following the Canterbury earthquake sequence of 2010–2011. The post-event safety assessment program was one of the largest and longest programs undertaken in recent times anywhere in the world. The effort engaged hundreds of engineering professionals throughout the country, and also sought expertise from outside, to perform post-earthquake structural safety inspections of more than 100,000 buildings in the city of Christchurch and the surrounding suburbs. While the building safety inspection procedure implemented was analogous to the ATC 20 program in the United States, many modifications were proposed and implemented in order to assess the large number of buildings that were subjected to strong and variable shaking during a period of two years. This note discusses some of the key aspects of the post-earthquake building safety inspection program and summarizes important lessons that can improve future earthquake response.

76 FR 32333 - Approval and Promulgation of Air Quality Implementation Plans; Pennsylvania; Revision to the...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-06

... duration of the timing of quality assurance audits performed by the Pennsylvania Department of...) Program--Quality Assurance Protocol for the Safety Inspection Program in Non-I/M Counties AGENCY... quality assurance program for its motor vehicle inspection and maintenance program (I/M program...

76 FR 2066 - Approval and Promulgation of Implementation Plans; Indiana; Removal of Vehicle Inspection and...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-12

... ozone maintenance plans. The Indiana Department of Environmental Management (IDEM) submitted this... Promulgation of Implementation Plans; Indiana; Removal of Vehicle Inspection and Maintenance Programs for Clark... to allow the State to discontinue the vehicle inspection and maintenance (I/M) program in Clark and...

9 CFR 307.1 - Facilities for Program employees.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Facilities for Program employees. 307.1 Section 307.1 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION FACILITIES FOR...

9 CFR 307.1 - Facilities for Program employees.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Facilities for Program employees. 307.1 Section 307.1 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION FACILITIES FOR...

9 CFR 307.1 - Facilities for Program employees.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false Facilities for Program employees. 307.1 Section 307.1 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION FACILITIES FOR...

National Program for Inspection of Non-Federal Dams. Lovejoy Pond Dam ME-00022, Androscoggin River Basin, North Wayne, Maine. Phase I Inspection Report.

DTIC Science & Technology

1979-04-01

programs for non-Federal dams. (3) To update, verify and complete the National Inventory of Dams. 1.2 DESCRIPTION OF PROJECT a. Location. The Lovejoy Pond...BUREAU OF STANDARDS- 1963-A 41 ANDROSCOGGIN RIVER BASIN NORTH WAYNE ,MAINE LOVEJOY POND DAM ME-00022 0 PHASE I INSPECTION REPORT NATIONAL DAM INSPECTION...side of necessar mnd idenifIr bioc Sigmmber) DAMS, INSPECTION, DAM SAFETY, * Androscoggin River Basin North Wayne, Maine Lovejoy Pond * 20. ABSTRACT

Utility of the Instability Severity Index Score in Predicting Failure After Arthroscopic Anterior Stabilization of the Shoulder.

PubMed

Phadnis, Joideep; Arnold, Christine; Elmorsy, Ahmed; Flannery, Mark

2015-08-01

The redislocation rate after arthroscopic stabilization for anterior glenohumeral instability is up to 30%. The Instability Severity Index Score (ISIS) was developed to preoperatively rationalize the risk of failure, but it has not yet been validated by an independent group. To assess the utility of the ISIS in predicting failure of arthroscopic anterior shoulder stabilization and to identify other preoperative factors for failure. Case-control study; Level of evidence, 3. A case-control study was performed on 141 consecutive patients, comparing those who suffered failure of arthroscopic stabilization with those who had successful arthroscopic stabilization. The mean follow-up time was 47 months (range, 24-132 months). The ISIS was applied retrospectively, and an analysis was performed to establish independent risk factors for failure. A receiver operator coefficient curve was constructed to set a threshold ISIS for considering alternative surgery. Of 141 patients, 19 (13.5%) suffered recurrent instability. The mean ISIS of the failed stabilization group was higher than that of the successful stabilization group (5.1 vs 1.7; P < .001). Independent risk factors for failure were Hill-Sachs lesion (P < .001), glenoid bone loss (P < .001), age <21 years at the time of surgery (P < .001), age at first dislocation (P = .01), competitive-level participation in sports (P < .001), and participation in contact or overhead sports (P = .03). The presence of glenoid bone loss carried the highest risk of failure (70%). There was a 70% risk of failure if the ISIS was ≥4, as opposed to a 4% risk of failure if the ISIS was <4. This is the first completely independent study to confirm that the ISIS is a useful preoperative tool. It is recommended that surgeons consider alternative forms of stabilization if the ISIS is ≥4. © 2015 The Author(s).

National Program for Inspection of Non-Federal Dams. Paper Mill Pond Dam (CT 00621), Connecticut River Basin, Vernon, Connecticut. Phase I Inspection Report.

DTIC Science & Technology

1981-03-01

HYDROLOGIC AND HYDRAULIC COMPUTATIONS E INFORMATION AS CONTAINED IN THE NATIONAL INVENTORY OF DAMS ,v ’walL.it, AM I OVERVIEV \\ PHOTO Iv 390 L-( ibb~ ~5~4 N...AS-A144 539 NATIONAL PROGRAM FOR INSPEGTION 0F NON-FEDERAL DAMS / PAPER MIL POND DAM (.(U CORPS OF ENGINEERS WALTHAM A S MA NEW ENGLANA DIV MAR...CATALOG NUMBER CT 00621A 4 TITLE (amdSubtile) S. TYPE OF REPORT & PERIOD’COVERED Paper Mill Pond Dam INSPECTION REPORT NATIONAL PROGRAM FOR INSPECTION

Inspection of aging aircraft: A manufacturer's perspective

NASA Technical Reports Server (NTRS)

Hagemaier, Donald J.

1992-01-01

Douglas, in conjunction with operators and regulators, has established interrelated programs to identify and address issues regarding inspection of aging aircraft. These inspection programs consist of the following: Supplemental Inspection Documents; Corrosion Prevention and Control Documents; Repair Assessment Documents; and Service Bulletin Compliance Documents. In addition, airframe manufacturers perform extended airframe fatigue tests to deal with potential problems before they can develop in the fleet. Lastly, nondestructive inspection (NDI) plays a role in all these programs through the detection of cracks, corrosion, and disbonds. However, improved and more cost effective NDI methods are needed. Some methods such as magneto-optic imaging, electronic shearography, Diffractor-Sight, and multi-parameter eddy current testing appear viable for near-term improvements in NDI of aging aircraft.

7 CFR 927.60 - Inspection and certification.

Code of Federal Regulations, 2010 CFR

2010-01-01

... WASHINGTON Order Regulating Handling Inspection § 927.60 Inspection and certification. (a) Handlers shall ship only fresh pears inspected by the Federal-State Inspection Service or under a program developed by... 7 Agriculture 8 2010-01-01 2010-01-01 false Inspection and certification. 927.60 Section 927.60...

Fast casual multicast

NASA Technical Reports Server (NTRS)

Birman, Kenneth; Schiper, Andre; Stephenson, Pat

1990-01-01

A new protocol is presented that efficiently implements a reliable, causally ordered multicast primitive and is easily extended into a totally ordered one. Intended for use in the ISIS toolkit, it offers a way to bypass the most costly aspects of ISIS while benefiting from virtual synchrony. The facility scales with bounded overhead. Measured speedups of more than an order of magnitude were obtained when the protocol was implemented within ISIS. One conclusion is that systems such as ISIS can achieve performance competitive with the best existing multicast facilities--a finding contradicting the widespread concern that fault-tolerance may be unacceptably costly.

Characterization of γ-ray background at IMAT beamline of ISIS Spallation Neutron Source

NASA Astrophysics Data System (ADS)

Festa, G.; Andreani, C.; Arcidiacono, L.; Burca, G.; Kockelmann, W.; Minniti, T.; Senesi, R.

2017-08-01

The environmental γ -ray background on the IMAT beamline at ISIS Spallation Neutron Source, Target Station 2, is characterized via γ spectroscopy. The measurements include gamma exposure at the imaging detector position, along with the gamma background inside the beamline. Present results are discussed and compared with previous measurements recorded at INES and VESUVIO beamlines operating at Target Station 1. They provide new outcome for expanding and optimizing the PGAA experimental capability at the ISIS neutron source for the investigation of materials, engineering components and cultural heritage objects at the ISIS neutron source.

Software Formal Inspections Guidebook

NASA Technical Reports Server (NTRS)

1993-01-01

The Software Formal Inspections Guidebook is designed to support the inspection process of software developed by and for NASA. This document provides information on how to implement a recommended and proven method for conducting formal inspections of NASA software. This Guidebook is a companion document to NASA Standard 2202-93, Software Formal Inspections Standard, approved April 1993, which provides the rules, procedures, and specific requirements for conducting software formal inspections. Application of the Formal Inspections Standard is optional to NASA program or project management. In cases where program or project management decide to use the formal inspections method, this Guidebook provides additional information on how to establish and implement the process. The goal of the formal inspections process as documented in the above-mentioned Standard and this Guidebook is to provide a framework and model for an inspection process that will enable the detection and elimination of defects as early as possible in the software life cycle. An ancillary aspect of the formal inspection process incorporates the collection and analysis of inspection data to effect continual improvement in the inspection process and the quality of the software subjected to the process.

National Dam Inspection Program. Laurel Run Dam. NDI ID Number PA-00380. DER ID Number 35-6, Pennsylvania Gas and Water Company. Susquehanna River Basin, Laurel Run, Lackawanna County, Pennsylvania Phase I Inspection Report,

DTIC Science & Technology

1980-04-01

Supply. g. Design and Construction History. Laurel Run Dam was constructed in 1594 by Martin Cawley, a contractor from Archbald. The construction was...1T6Ace joly PHASE I INSPECTION REPORT -4 NATIONAL DAM INSPECTION PROGRAM Lime LAUREL RUN DAM PENNSYLVANIA GAS AND WATER COMPANY RESERVOIR AREA

A Dynamic Approach to Make CDS/ISIS Databases Interoperable over the Internet Using the OAI Protocol

ERIC Educational Resources Information Center

Jayakanth, F.; Maly, K.; Zubair, M.; Aswath, L.

2006-01-01

Purpose: A dynamic approach to making legacy databases, like CDS/ISIS, interoperable with OAI-compliant digital libraries (DLs). Design/methodology/approach: There are many bibliographic databases that are being maintained using legacy database systems. CDS/ISIS is one such legacy database system. It was designed and developed specifically for…

ANNUAL RADIOACTIVE WASTE TANK INSPECTION PROGRAM - 2011

DOE Office of Scientific and Technical Information (OSTI.GOV)

West, B.; Waltz, R.

2012-06-21

Aqueous radioactive wastes from Savannah River Site (SRS) separations and vitrification processes are contained in large underground carbon steel tanks. Inspections made during 2011 to evaluate these vessels and other waste handling facilities along with evaluations based on data from previous inspections are the subject of this report. The 2011 inspection program revealed that the structural integrity and waste confinement capability of the Savannah River Site waste tanks were maintained. All inspections scheduled per SRR-LWE-2011-00026, HLW Tank Farm Inspection Plan for 2011, were completed. Ultrasonic measurements (UT) performed in 2011 met the requirements of C-ESR-G-00006, In-Service Inspection Program for Highmore » Level Waste Tanks, Rev. 3, and WSRC-TR-2002-00061, Rev.6. UT inspections were performed on Tanks 25, 26 and 34 and the findings are documented in SRNL-STI-2011-00495, Tank Inspection NDE Results for Fiscal Year 2011, Waste Tanks 25, 26, 34 and 41. A total of 5813 photographs were made and 835 visual and video inspections were performed during 2011. A potential leaksite was discovered at Tank 4 during routine annual inspections performed in 2011. The new crack, which is above the allowable fill level, resulted in no release to the environment or tank annulus. The location of the crack is documented in C-ESR-G-00003, SRS High Level Waste Tank Leaksite Information, Rev.6.« less

30 CFR 842.11 - Federal inspections and monitoring.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 30 Mineral Resources 3 2014-07-01 2014-07-01 false Federal inspections and monitoring. 842.11... INTERIOR PERMANENT PROGRAM INSPECTION AND ENFORCEMENT PROCEDURES FEDERAL INSPECTIONS AND MONITORING § 842.11 Federal inspections and monitoring. (a) Authorized representatives of the Secretary shall conduct...

30 CFR 842.11 - Federal inspections and monitoring.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 30 Mineral Resources 3 2013-07-01 2013-07-01 false Federal inspections and monitoring. 842.11... INTERIOR PERMANENT PROGRAM INSPECTION AND ENFORCEMENT PROCEDURES FEDERAL INSPECTIONS AND MONITORING § 842.11 Federal inspections and monitoring. (a) Authorized representatives of the Secretary shall conduct...

30 CFR 842.11 - Federal inspections and monitoring.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 30 Mineral Resources 3 2012-07-01 2012-07-01 false Federal inspections and monitoring. 842.11... INTERIOR PERMANENT PROGRAM INSPECTION AND ENFORCEMENT PROCEDURES FEDERAL INSPECTIONS AND MONITORING § 842.11 Federal inspections and monitoring. (a) Authorized representatives of the Secretary shall conduct...

30 CFR 842.11 - Federal inspections and monitoring.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 3 2011-07-01 2011-07-01 false Federal inspections and monitoring. 842.11... INTERIOR PERMANENT PROGRAM INSPECTION AND ENFORCEMENT PROCEDURES FEDERAL INSPECTIONS AND MONITORING § 842.11 Federal inspections and monitoring. (a) Authorized representatives of the Secretary shall conduct...

30 CFR 842.11 - Federal inspections and monitoring.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Federal inspections and monitoring. 842.11... INTERIOR PERMANENT PROGRAM INSPECTION AND ENFORCEMENT PROCEDURES FEDERAL INSPECTIONS AND MONITORING § 842.11 Federal inspections and monitoring. (a) Authorized representatives of the Secretary shall conduct...

Early ERP Signature of Hearing Impairment in Visual Rhyme Judgment

PubMed Central

Classon, Elisabet; Rudner, Mary; Johansson, Mikael; Rönnberg, Jerker

2013-01-01

Postlingually acquired hearing impairment (HI) is associated with changes in the representation of sound in semantic long-term memory. An indication of this is the lower performance on visual rhyme judgment tasks in conditions where phonological and orthographic cues mismatch, requiring high reliance on phonological representations. In this study, event-related potentials (ERPs) were used for the first time to investigate the neural correlates of phonological processing in visual rhyme judgments in participants with acquired HI and normal hearing (NH). Rhyme task word pairs rhymed or not and had matching or mismatching orthography. In addition, the inter-stimulus interval (ISI) was manipulated to be either long (800 ms) or short (50 ms). Long ISIs allow for engagement of explicit, top-down processes, while short ISIs limit the involvement of such mechanisms. We hypothesized lower behavioral performance and N400 and N2 deviations in HI in the mismatching rhyme judgment conditions, particularly in short ISI. However, the results showed a different pattern. As expected, behavioral performance in the mismatch conditions was lower in HI than in NH in short ISI, but ERPs did not differ across groups. In contrast, HI performed on a par with NH in long ISI. Further, HI, but not NH, showed an amplified N2-like response in the non-rhyming, orthographically mismatching condition in long ISI. This was also the rhyme condition in which participants in both groups benefited the most from the possibility to engage top-down processes afforded with the longer ISI. Taken together, these results indicate an early ERP signature of HI in this challenging phonological task, likely reflecting use of a compensatory strategy. This strategy is suggested to involve increased reliance on explicit mechanisms such as articulatory recoding and grapheme-to-phoneme conversion. PMID:23653613

In vitro evaluation of phosphorothioate oligonucleotides targeted to the E2 mRNA of papillomavirus: potential treatment for genital warts.

PubMed Central

Cowsert, L M; Fox, M C; Zon, G; Mirabelli, C K

1993-01-01

Papillomaviruses induce benign proliferative lesions, such as genital warts, in humans. The E2 gene product is thought to play a major role in the regulation of viral transcription and DNA replication and may represent a rational target for an antisense oligonucleotide drug action. Phosphorothioate oligonucleotides complementary to E2 mRNAs were synthesized and tested in a series of in vitro bovine papillomavirus (BPV) and human papillomavirus (HPV) models for the ability to inhibit E2 transactivation and virus-induced focus formation. The most active BPV-specific compounds were complementary to the mRNA cap region (ISIS 1751), the translation initiation region for the full-length E2 transactivator (ISIS 1753), and the translation initiation region for the E2 transrepressor mRNA (ISIS 1755). ISIS 1751 and ISIS 1753 were found to reduce E2-dependent transactivation and viral focus formation in a sequence-specific and concentration-dependent manner. ISIS 1755 increased E2 transactivation in a dose-dependent manner but had no effect on focus formation. Oligonucleotides with a chain length of 20 residues had optimal activity in the E2 transactivation assay. On the basis of the above observations, ISIS 2105, a 20-residue phosphorothioate oligonucleotide targeted to the translation initiation of both HPV type 6 (HPV-6) and HPV-11 E2 mRNA, was designed and shown to inhibit E2-dependent transactivation by HPV-11 E2 expressed from a surrogate promoter. These observations support the rationale of E2 as a target for antiviral therapy against papillomavirus infections and specifically identify ISIS 2105 as a candidate antisense oligonucleotide for the treatment of genital warts induced by HPV-6 and HPV-11. Images PMID:8383937

Immunotoxic cholinergic lesions in the basal forebrain reverse the effects of entorhinal cortex lesions on conditioned odor aversion in the rat.

PubMed

Ferry, Barbara; Herbeaux, Karin; Cosquer, Brigitte; Traissard, Natalia; Galani, Rodrigue; Cassel, Jean-Christophe

2007-07-01

Conditioned odor aversion (COA) corresponds to the avoidance of an odorized-tasteless solution (conditioned stimulus, CS) previously paired with toxicosis. COA occurs only when the interstimulus interval (ISI) is kept short, suggesting that the memory trace of the odor is subject to rapid decay. Previous experiments have shown that the entorhinal cortex (EC) is involved in the acquisition of COA, since lesion of the EC rendered COA tolerant to long ISI. Because EC lesions induce a septo-hippocampal cholinergic sprouting, the present experiment investigated whether COA tolerance to long ISI may be linked to this sprouting reaction. In a first experiment, male Long-Evans rats subjected to bilateral excitotoxic EC lesions combined to intracerebroventricular infusions of the selective cholinergic immunotoxin 192 IgG-saporin were exposed to odor-toxicosis pairing using a long ISI (120 min). Results showed that EC-lesioned rats displayed COA with the long ISI but not the control groups. In rats with EC combined to 192 IgG-saporin lesions, histological analysis demonstrated no evidence for cholinergic septo-hippocampal sprouting. In a second experiment, animals with 192-IgG saporin lesion showed a marked COA with a short ISI (5 min). These results suggest that the COA with the long ISI found in rats with EC lesions might involve a functional activity related to the EC lesion-induced hippocampal cholinergic sprouting. As the injection of 192 IgG-saporin alone did not affect COA with a short ISI, our data also point to a possible role of hippocampal cholinergic neurons in the modulation of memory processes underlying COA.

Assessment of the effects of ISIS 2302, an anti-sense inhibitor of human ICAM-1, on cellular and humoral immunity in mice.

PubMed

Henry, Scott P; Levin, Arthur A; White, Kimber; Mennear, John H

2006-12-01

ISIS 2302 is a phosphorothioate oligonucleotide designed to inhibit human ICAM-1 and is intended for treatment of inflammatory diseases. Molecules of this class are known to elicit pro-inflammatory effects, and immunotoxicity studies were performed in mice to elucidate the nature of effects of ISIS 2302 on mammalian immune function. ISIS 2302 (1, 5, 20, or 50 mg/kg/dose) was administered intravenously every other day for 27 days. The pro-inflammatory properties of the drug were observed at doses > or = 20 mg/kg. A dose-dependent increase in spleen weight was associated with increased absolute splenocyte and B-lymphocyte counts after the 50 mg/kg/dose regimen. The mitogenic response of B-lymphocytes to bacterial lipopolysaccharide was increased after the 20 and 50 mg/kg/doses but antibody-forming cell activities remained unchanged. Total serum IgG concentration was decreased after the 20 and 50 mg/kg/dose regimens but IgM titers were unchanged. Increases in IL-6, IL-12, and MCP-1 as well as NK cell activity were observed after administration of 20 and 50 mg/kg/dose. Cytotoxic T-lymphocyte activity was decreased by the 50 mg/kg/dose regimen. Other changes in immune function were not observed in ISIS 2302-dosed mice. ISIS 3082, a murine active ICAM-1 inhibitor, was used to demonstrate the anti-inflammatory activity of ICAM-1 inhibition in the 2,4-dinitrofluorobenzene-induced contact sensitization model. Intravenous administration of 1 mg/kg of ISIS 3082 every other day for 27 days was unequivocally anti-inflammatory in the contact sensitization test. The results of these experiments support the conclusion that the prophlogistic effects of ISIS 2302 in mice are observed only at suprapharmacologic doses.

Pharmacodynamics and subchronic toxicity in mice and monkeys of ISIS 388626, a second-generation antisense oligonucleotide that targets human sodium glucose cotransporter 2.

PubMed

Zanardi, Thomas A; Han, Su-Cheol; Jeong, Eun Ju; Rime, Soyub; Yu, Rosie Z; Chakravarty, Kaushik; Henry, Scott P

2012-11-01

ISIS 388626, a 2'-methoxyethyl (MOE)-modified antisense oligonucleotide (ASO) that targets human sodium glucose cotransporter 2 (SGLT2) mRNA, is in clinical trials for the management of diabetes. SGLT2 plays a pivotal role in renal glucose reabsorption, and inhibition of SGLT2 is anticipated to reduce hyperglycemia in diabetic subjects by increasing urinary glucose elimination. To selectively inhibit SGLT2 in the kidney, ISIS 388626 was designed as a "shortmer" ASO, consisting of only 12 nucleotides with two 2'-MOE-modified nucleotides at the termini. Mice and monkeys received up to 30 mg/kg/week ISIS 388626 via subcutaneous injection for 6 or 13 weeks. Dose-dependent decreases in renal SGLT2 mRNA expression were observed, which correlated with dose-related increases in glucosuria without concomitant hypoglycemia. There were no histologic changes in the kidney attributed to SGLT2 inhibition after 6 or 13 weeks of treatment. The remaining changes observed in these studies were typical of those produced in these species by the administration of oligonucleotides, correlated with high doses of ISIS 388626, and were unrelated to the inhibition of SGLT2 expression. The kidney contained the highest concentration of ISIS 388626, and dose-dependent basophilic granule accumulation in tubular epithelial cells of the kidney, which is evidence of oligonucleotide accumulation in these cells, was the only histologic change identified. No changes in kidney function were observed. These results revealed only readily reversible changes after the administration of ISIS 388626 and support the continued investigation of the safety and efficacy of ISIS 388626 in human trials.

Cross-species pharmacokinetic comparison from mouse to man of a second-generation antisense oligonucleotide, ISIS 301012, targeting human apolipoprotein B-100.

PubMed

Yu, Rosie Z; Kim, Tae-Won; Hong, An; Watanabe, Tanya A; Gaus, Hans J; Geary, Richard S

2007-03-01

The pharmacokinetics of a 2'-O-(2-methoxyethyl)-modified oligonucleotide, ISIS 301012 [targeting human apolipoprotein B-100 (apoB-100)], was characterized in mouse, rat, monkey, and human. Plasma pharmacokinetics following parental administration was similar across species, exhibiting a rapid distribution phase with t(1/2alpha) of several hours and a prolonged elimination phase with t(1/2beta) of days. The prolonged elimination phase represents equilibrium between tissues and circulating drug due to slow elimination from tissues. Absorption was nearly complete following s.c. injection, with bioavailability ranging from 80 to 100% in monkeys. Plasma clearance scaled well across species as a function of body weight alone, and this correlation was improved when corrected for plasma protein binding. In all of the animal models studied, the highest tissue concentrations of ISIS 301012 were observed in kidney and liver. Urinary excretion was less than 3% in monkeys and human in the first 24 h. ISIS 301012 is highly bound to plasma proteins, probably preventing rapid removal by renal filtration. However, following 25 mg/kg s.c. administration in mouse and 5-mg/kg i.v. bolus administration in rat, plasma concentrations of ISIS 301012 exceeded their respective protein binding capacity. Thus, urinary excretion increased to 16% or greater within the first 24 h. Albeit slow, urinary excretion of ISIS 301012 and its shortened metabolites is the ultimate elimination pathway of this compound, as demonstrated by 32% of dose recovered in total excreta by 14 days in a rat mass balance study. The pharmacokinetics of ISIS 301012 in human is predictable from the pharmacokinetics measured in animals. The pharmacokinetic properties of ISIS 301012 provide guidance for clinical development and support infrequent dose administration.

Neurophysiological and Behavioral Responses of Mandarin Lexical Tone Processing

PubMed Central

Yu, Yan H.; Shafer, Valerie L.; Sussman, Elyse S.

2017-01-01

Language experience enhances discrimination of speech contrasts at a behavioral- perceptual level, as well as at a pre-attentive level, as indexed by event-related potential (ERP) mismatch negativity (MMN) responses. The enhanced sensitivity could be the result of changes in acoustic resolution and/or long-term memory representations of the relevant information in the auditory cortex. To examine these possibilities, we used a short (ca. 600 ms) vs. long (ca. 2,600 ms) interstimulus interval (ISI) in a passive, oddball discrimination task while obtaining ERPs. These ISI differences were used to test whether cross-linguistic differences in processing Mandarin lexical tone are a function of differences in acoustic resolution and/or differences in long-term memory representations. Bisyllabic nonword tokens that differed in lexical tone categories were presented using a passive listening multiple oddball paradigm. Behavioral discrimination and identification data were also collected. The ERP results revealed robust MMNs to both easy and difficult lexical tone differences for both groups at short ISIs. At long ISIs, there was either no change or an enhanced MMN amplitude for the Mandarin group, but reduced MMN amplitude for the English group. In addition, the Mandarin listeners showed a larger late negativity (LN) discriminative response than the English listeners for lexical tone contrasts in the long ISI condition. Mandarin speakers outperformed English speakers in the behavioral tasks, especially under the long ISI conditions with the more similar lexical tone pair. These results suggest that the acoustic correlates of lexical tone are fairly robust and easily discriminated at short ISIs, when the auditory sensory memory trace is strong. At longer ISIs beyond 2.5 s language-specific experience is necessary for robust discrimination. PMID:28321179

Industry assessment of human factors in aviation maintenance and inspection research program : an assessment of industry awareness and use of the Federal Aviation Administration Office of Aviation Medicine Human Factors in Aviation Maintenance and Inspection Research and Development Program from 1989 through 1998

DOT National Transportation Integrated Search

1998-03-01

Ten years ago the Federal Aviation Administration (FAA) Office of Aviation Medicine embarked on a research and development program dedicated to human factors in aviation maintenance and inspection. Since 1989 FAA has invested over $12M in maintenance...

Highway bridge inspection : state-of-the-practice survey

DOT National Transportation Integrated Search

2001-04-01

The congressionally mandated National Bridge Inspection program requires States to periodically inventory, inspect, and rate all highway bridges on public roads. The National Bridge Inspection Standards, implemented in 1971, prescribe minimum require...

9 CFR 306.2 - Program employees to have access to establishments.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false Program employees to have access to establishments. 306.2 Section 306.2 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATIO...

9 CFR 306.2 - Program employees to have access to establishments.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Program employees to have access to establishments. 306.2 Section 306.2 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATIO...

9 CFR 306.2 - Program employees to have access to establishments.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Program employees to have access to establishments. 306.2 Section 306.2 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATIO...

14 CFR 135.429 - Required inspection personnel.

Code of Federal Regulations, 2011 CFR

2011-01-01

... item of work that is a required inspection item that is part of the flight control system shall be... supervision and control of an inspection unit. (c) No person may perform a required inspection if that person... maintenance program; (4) Each item is inspected after each flight until the item has been inspected by an...

14 CFR 135.429 - Required inspection personnel.

Code of Federal Regulations, 2014 CFR

2014-01-01

... item of work that is a required inspection item that is part of the flight control system shall be... supervision and control of an inspection unit. (c) No person may perform a required inspection if that person... maintenance program; (4) Each item is inspected after each flight until the item has been inspected by an...

14 CFR 135.429 - Required inspection personnel.

Code of Federal Regulations, 2013 CFR

2013-01-01

... item of work that is a required inspection item that is part of the flight control system shall be... supervision and control of an inspection unit. (c) No person may perform a required inspection if that person... maintenance program; (4) Each item is inspected after each flight until the item has been inspected by an...

14 CFR 135.429 - Required inspection personnel.

Code of Federal Regulations, 2012 CFR

2012-01-01

... item of work that is a required inspection item that is part of the flight control system shall be... supervision and control of an inspection unit. (c) No person may perform a required inspection if that person... maintenance program; (4) Each item is inspected after each flight until the item has been inspected by an...

14 CFR 135.429 - Required inspection personnel.

Code of Federal Regulations, 2010 CFR

2010-01-01

... item of work that is a required inspection item that is part of the flight control system shall be... supervision and control of an inspection unit. (c) No person may perform a required inspection if that person... maintenance program; (4) Each item is inspected after each flight until the item has been inspected by an...

Massively parallel E-beam inspection: enabling next-generation patterned defect inspection for wafer and mask manufacturing

NASA Astrophysics Data System (ADS)

Malloy, Matt; Thiel, Brad; Bunday, Benjamin D.; Wurm, Stefan; Mukhtar, Maseeh; Quoi, Kathy; Kemen, Thomas; Zeidler, Dirk; Eberle, Anna Lena; Garbowski, Tomasz; Dellemann, Gregor; Peters, Jan Hendrik

2015-03-01

SEMATECH aims to identify and enable disruptive technologies to meet the ever-increasing demands of semiconductor high volume manufacturing (HVM). As such, a program was initiated in 2012 focused on high-speed e-beam defect inspection as a complement, and eventual successor, to bright field optical patterned defect inspection [1]. The primary goal is to enable a new technology to overcome the key gaps that are limiting modern day inspection in the fab; primarily, throughput and sensitivity to detect ultra-small critical defects. The program specifically targets revolutionary solutions based on massively parallel e-beam technologies, as opposed to incremental improvements to existing e-beam and optical inspection platforms. Wafer inspection is the primary target, but attention is also being paid to next generation mask inspection. During the first phase of the multi-year program multiple technologies were reviewed, a down-selection was made to the top candidates, and evaluations began on proof of concept systems. A champion technology has been selected and as of late 2014 the program has begun to move into the core technology maturation phase in order to enable eventual commercialization of an HVM system. Performance data from early proof of concept systems will be shown along with roadmaps to achieving HVM performance. SEMATECH's vision for moving from early-stage development to commercialization will be shown, including plans for development with industry leading technology providers.

Member Perceptions of Informal Science Institution Graduate Certificate Program: Case Study of a Community of Practice

NASA Astrophysics Data System (ADS)

Ball, Lois A.

This research attempted to understand the experiences of a cohort of informal and formal science educators and informal science institution (ISI) community representatives during and after completion of a pilot graduate certificate program. Informal science educators (ISEs) find limited opportunities for professional development and support which influence their contributions to America's science literacy and school science education. This emergent design nested case study described how an innovative program provided professional development and enabled growth in participants' abilities to contribute to science literacy. Data were collected through interviews, participant observations, and class artifacts. The program by design and constituency was the overarching entity that accounted for members' experiences. Three principal aspects of the ISI certificate program and cohort which influenced perceptions and reported positive outcomes were (1) the cohort's composition and their collaborative activities which established a vigorous community of practice and fostered community building, mentoring, and networking, (2) long term program design and implementation which promoted experiential learning in a generative classroom, and (3) ability of some members who were able to be independent or autonomous learners to embrace science education reform strategies for greater self-efficacy and career advancement. This research extends the limited literature base for professional development of informal science educators and may benefit informal science institutions, informal and formal science educators, science education reform efforts, and public education and science-technology-society understanding. The study may raise awareness of the need to establish more professional development opportunities for ISEs and to fund professional development. Further, recognizing and appreciating informal science educators as a diverse committed community of professionals who positively influence science education for everyone is essential.

ISIS and Social Media: The Combatant Commander’s Guide to Countering ISIS’s Social Media Campaign

DTIC Science & Technology

2015-06-07

temptation to use mirror imaging, or to try to fit ISIS into a simple, pre-determined ideological box. This is especially important when trying to design...fighters play an important role as willing suicide bombers and they also portray the image that the Islamic State stands as a transnational force of

The Interpersonal Shame Inventory for Asian Americans: Scale Development and Psychometric Properties

PubMed Central

Wong, Y. Joel; Kim, Bryan S. K.; Nguyen, Chi P.; Cheng, Janice Ka Yan; Saw, Anne

2016-01-01

This article reports the development and psychometric properties of the Interpersonal Shame Inventory (ISI), a culturally salient and clinically relevant measure of interpersonal shame for Asian Americans. Across 4 studies involving Asian American college students, the authors provided evidence for this new measure’s validity and reliability. Exploratory factor analyses and confirmatory factor analyses provided support for a model with 2 correlated factors: external shame (arising from concerns about others’ negative evaluations) and family shame (arising from perceptions that one has brought shame to one’s family), corresponding to 2 subscales: ISI-E and ISI-F, respectively. Evidence for criterion-related, concurrent, discriminant, and incremental validity was demonstrated by testing the associations between external shame and family shame and immigration/international status, generic state shame, face concerns, thwarted belongingness, perceived burdensomeness, self-esteem, depressive symptoms, and suicide ideation. External shame and family shame also exhibited differential relations with other variables. Mediation findings were consistent with a model in which family shame mediated the effects of thwarted belongingness on suicide ideation. Further, the ISI subscales demonstrated high alpha coefficients and test–retest reliability. These findings are discussed in light of the conceptual, methodological, and clinical contributions of the ISI. PMID:24188650

Masked Priming Effects in Aphasia: Evidence for Altered Automatic Spreading Activation

PubMed Central

Silkes, JoAnn P.; Rogers, Margaret A.

2015-01-01

Purpose Previous research has suggested that impairments of automatic spreading activation may underlie some aphasic language deficits. This study further investigated the status of automatic spreading activation in individuals with aphasia as compared with typical adults. Method Participants were 21 individuals with aphasia (12 fluent, 9 non-fluent) and 31 typical adults. Reaction time data were collected on a lexical decision task with masked repetition primes, assessed at 11 different interstimulus intervals (ISIs). Masked primes were used to assess automatic spreading activation without the confound of conscious processing. The various ISIs were used to assess the time to onset, and duration, of priming effects. Results The control group showed maximal priming in the 200 ms ISI condition, with significant priming at a range of ISIs surrounding that peak. Participants with both fluent and non-fluent aphasia showed maximal priming effects in the 250 ms ISI condition, and primed across a smaller range of ISIs than the control group. Conclusions Results suggest that individuals with aphasia have slowed automatic spreading activation, and impaired maintenance of activation over time, regardless of fluency classification. These findings have implications for understanding aphasic language impairment and for development of aphasia treatments designed directly address automatic language processes. PMID:22411281

Masked priming effects in aphasia: evidence of altered automatic spreading activation.

PubMed

Silkes, JoAnn P; Rogers, Margaret A

2012-12-01

Previous research has suggested that impairments of automatic spreading activation may underlie some aphasic language deficits. The current study further investigated the status of automatic spreading activation in individuals with aphasia as compared with typical adults. Participants were 21 individuals with aphasia (12 fluent, 9 nonfluent) and 31 typical adults. Reaction time data were collected on a lexical decision task with masked repetition primes, assessed at 11 different interstimulus intervals (ISIs). Masked primes were used to assess automatic spreading activation without the confound of conscious processing. The various ISIs were used to assess the time to onset and duration of priming effects. The control group showed maximal priming in the 200-ms ISI condition, with significant priming at a range of ISIs surrounding that peak. Participants with both fluent and nonfluent aphasia showed maximal priming effects in the 250-ms ISI condition and primed across a smaller range of ISIs than did the control group. Results suggest that individuals with aphasia have slowed automatic spreading activation and impaired maintenance of activation over time, regardless of fluency classification. These findings have implications for understanding aphasic language impairment and for development of aphasia treatments designed to directly address automatic language processes.

Quantifying the benefits of the Florida Transit Research Inspection Procurement Services (TRIPS) program.

DOT National Transportation Integrated Search

2013-04-01

This study details the analysis of the Florida Transit Research Inspection Procurement Services (TRIPS) Program. It provides a comparative assessment of the program with respect to out-of-state practice, provides recommendations to improve life cycle...

National Program of Inspection of Non-Federal Dams.

DTIC Science & Technology

1982-05-01

actions to improve the .;,.fety of Federal dams . 3 B. PROGRAM REVITALIZATION Subsequent to the failure of the Teton Dam , near Newdale, Idaho, in June...development of hydrostatic heads sufficient to create in the area downstream of the dam sand boils that erode materials by the phenomenon known as " piping " and...Eh irmmhhhommlm mhhhhmmmmhhlo US Arm op National Program of Inspection of Non-Federal Dams Final Report to Congress The National Dam Inspection Act of

Impact of a letter-grade program on restaurant sanitary conditions and diner behavior in New York City.

PubMed

Wong, Melissa R; McKelvey, Wendy; Ito, Kazuhiko; Schiff, Corinne; Jacobson, J Bryan; Kass, Daniel

2015-03-01

We evaluated the impact of the New York City restaurant letter-grading program on restaurant hygiene, food safety practices, and public awareness. We analyzed data from 43,448 restaurants inspected between 2007 and 2013 to measure changes in inspection score and violation citations since program launch in July 2010. We used binomial regression to assess probability of scoring 0 to 13 points (A-range score). Two population-based random-digit-dial telephone surveys assessed public perceptions of the program. After we controlled for repeated restaurant observations, season of inspection, and chain restaurant status, the probability of scoring 0 to 13 points on an unannounced inspection increased 35% (95% confidence interval [CI]=31%, 40%) 3 years after compared with 3 years before grading. There were notable improvements in compliance with some specific requirements, including having a certified kitchen manager on site and being pest-free. More than 91% (95% CI=88%, 94%) of New Yorkers approved of the program and 88% (95% CI=85%, 92%) considered grades in dining decisions in 2012. Restaurant letter grading in New York City has resulted in improved sanitary conditions on unannounced inspection, suggesting that the program is an effective regulatory tool.

9 CFR 355.5 - Drawings.

Code of Federal Regulations, 2011 CFR

2011-01-01

... and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION... CERTIFICATION CERTIFIED PRODUCTS FOR DOGS, CATS, AND OTHER CARNIVORA; INSPECTION, CERTIFICATION, AND... Poultry Inspection Program, Food Safety and Inspection Service, U.S. Department of Agriculture, covering a...

Programming with process groups: Group and multicast semantics

NASA Technical Reports Server (NTRS)

Birman, Kenneth P.; Cooper, Robert; Gleeson, Barry

1991-01-01

Process groups are a natural tool for distributed programming and are increasingly important in distributed computing environments. Discussed here is a new architecture that arose from an effort to simplify Isis process group semantics. The findings include a refined notion of how the clients of a group should be treated, what the properties of a multicast primitive should be when systems contain large numbers of overlapping groups, and a new construct called the causality domain. A system based on this architecture is now being implemented in collaboration with the Chorus and Mach projects.

Shipshape: sanitation inspections on cruise ships, 1990-2005, Vessel Sanitation Program, Centers for Disease Control and Prevention.

PubMed

Cramer, Elaine H; Blanton, Curtis J; Otto, Charles

2008-03-01

In the course of a successful collaboration between the Centers for Disease Control and Prevention (CDC) and the cruise ship industry on reducing common-source outbreaks, CDC's Vessel Sanitation Program (VSP) has expanded its training, education, and cruise ship inspection programs. The study reported here evaluated 15 years of ship sanitation inspection data from the National Center for Environmental Health and assessed performance in specific sanitation categories from 1996 to 2005. During the period 1990-2005, scores from cruise ship environmental sanitation inspections steadily improved. The percentage of inspections with violations decreased among five of nine categories. Those five categories were Washing Facilities, Contact Surfaces, Facility Maintenance, Food Handling, and Communicable Disease Practices. Inspection violations increased proportionally in the categories of Swimming Pools and Water System Protection/Chart Recording. Overall continued good performance in most sanitation categories is likely attributable to on-site training during inspections, improvements in ship construction, and a switch from hot-holding temperatures to time limits as a public health control for foods on display.

National Program for Inspection of Non-Federal Dams. Chase Pond Dam (NH 00255), NHWRB Number 253.02, Merrimack River Basin, Wilmot, New Hampshire. Phase I Inspection Report.

DTIC Science & Technology

1980-03-01

STANDAROS-1963-A L ~.°.. o...... 1....MERRIMACK RIVER BASIN -!. WILMOT , NEW HAMPSHIRE ’,- CHASE POND DAM NH 00255 NHWRB NO. 253.02 r PHASE I...Continue on fewsorsp side #0 .o..oemay and Ientify by black Muthot) - DAMS, NSPECTION, PAM S’AFETY, Merrimack River Basin. * Wilmot , New Hampshire...MERRIMACK RIVER BASIN R WILMOT , NEW HAMPSHIRE - - PHASE I INSPECTION REPORT NATIONAL DAM INSPECTION PROGRAM :: : I

National Program for Inspection of Non-Federal Dams. Provin Mountain Reservoir (MA 00528) Connecticut River Basin, Agawam, Massachusetts. Phase I Inspection Report.

DTIC Science & Technology

1981-06-01

The following deficiencies were observed at the site: areas of * . localized sloughing in the rock slope of the east and west sides of Reservoir No. 1... WEST SPRINGFIELD, MASS QUADRANGLE 1979 Vi NATIONAL DAM INSPECTION PROGRAM PHASE I INSPECTION REPORT PROVIN MOUNTAIN RESERVOIR SECTION 1 PROJECT...his address is Northwest Street, West Feeding Fills, Agawam, Massa- chusetts (telephone 413/786-3030). . (g) Purpose of the Dar. Provin Mountain

Evaluating practical vs. theoretical inspection system capability with a new programmed defect test mask designed for 3X and 4X technology nodes

NASA Astrophysics Data System (ADS)

Glasser, Joshua; Pratt, Tim

2008-10-01

Programmed defect test masks serve the useful purpose of evaluating inspection system sensitivity and capability. It is widely recognized that when evaluating inspection system capability, it is important to understand the actual sensitivity of the inspection system in production; yet unfortunately we have observed that many test masks are a more accurate judge of theoretical sensitivity rather than real-world usable capability. Use of ineffective test masks leave the purchaser of inspection equipment open to the risks of over-estimating the capability of their inspection solution and overspecifying defect sensitivity to their customers. This can result in catastrophic yield loss for device makers. In this paper we examine some of the lithography-related technology advances which place an increasing burden on mask inspection complexity, such as MEEF, defect printability estimation, aggressive OPC, double patterning, and OPC jogs. We evaluate the key inspection system component contributors to successful mask inspection, including what can "go wrong" with these components. We designed and fabricated a test mask which both (a) more faithfully represents actual production use cases; and (b) stresses the key components of the inspection system. This mask's patterns represent 32nm, 36nm, and 45nm logic and memory technology including metal and poly like background patterns with programmed defects. This test mask takes into consideration requirements of advanced lithography, such as MEEF, defect printability, assist features, nearly-repetitive patterns, and data preparation. This mask uses patterns representative of 32nm, 36nm, and 45nm logic, flash, and DRAM technology. It is specifically designed to have metal and poly like background patterns with programmed defects. The mask is complex tritone and was designed for annular immersion lithography.

9 CFR 381.109 - Form of official poultry inspection certificate.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Form of official poultry inspection certificate. 381.109 Section 381.109 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE.... Department of Agriculture Animal and Plant Health Inspection Service Meat and Poultry Inspection Program...

44 CFR 59.30 - A pilot inspection procedure.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false A pilot inspection procedure... PROVISIONS Pilot Inspection Program § 59.30 A pilot inspection procedure. (a) Purpose. This section sets forth the criteria for implementing a pilot inspection procedure in Monroe County and the Village of...

44 CFR 59.30 - A pilot inspection procedure.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false A pilot inspection procedure... PROVISIONS Pilot Inspection Program § 59.30 A pilot inspection procedure. (a) Purpose. This section sets forth the criteria for implementing a pilot inspection procedure in Monroe County and the Village of...

46 CFR 162.028-6 - Examinations, tests, and inspections.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 6 2010-10-01 2010-10-01 false Examinations, tests, and inspections. 162.028-6 Section... Type § 162.028-6 Examinations, tests, and inspections. (a) Full examinations, tests, and inspections to..., inspections, and tests as to satisfy himself that the quality assurance program of the manufacturer is...

29 CFR 1960.31 - Inspections by OSHA.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) BASIC PROGRAM ELEMENTS FOR FEDERAL EMPLOYEE OCCUPATIONAL SAFETY AND HEALTH PROGRAMS AND RELATED... scheduled inspections as an integral part of OSHA's evaluation of an agency's safety and health program in...

29 CFR 1960.31 - Inspections by OSHA.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) BASIC PROGRAM ELEMENTS FOR FEDERAL EMPLOYEE OCCUPATIONAL SAFETY AND HEALTH PROGRAMS AND RELATED... scheduled inspections as an integral part of OSHA's evaluation of an agency's safety and health program in...

29 CFR 1960.31 - Inspections by OSHA.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) BASIC PROGRAM ELEMENTS FOR FEDERAL EMPLOYEE OCCUPATIONAL SAFETY AND HEALTH PROGRAMS AND RELATED... scheduled inspections as an integral part of OSHA's evaluation of an agency's safety and health program in...

29 CFR 1960.87 - Objectives.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., organize and conduct field council meetings or programs which will give technical advice and information on... variety of ways. For example, field councils could organize and conduct training programs for employee... inspections, or, on request, conduct inspections and evaluations of the agencies' safety and health programs...

29 CFR 1960.31 - Inspections by OSHA.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) BASIC PROGRAM ELEMENTS FOR FEDERAL EMPLOYEE OCCUPATIONAL SAFETY AND HEALTH PROGRAMS AND RELATED... scheduled inspections as an integral part of OSHA's evaluation of an agency's safety and health program in...

29 CFR 1960.31 - Inspections by OSHA.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) BASIC PROGRAM ELEMENTS FOR FEDERAL EMPLOYEE OCCUPATIONAL SAFETY AND HEALTH PROGRAMS AND RELATED... scheduled inspections as an integral part of OSHA's evaluation of an agency's safety and health program in...

Interactional Markers in English Medical Research Articles Written by Iranian and Native Authors: A Contrastive Metadiscourse Analysis of Method Section

ERIC Educational Resources Information Center

Ghadyani, Fariba; Tahririan, Mohammad Hassan

2014-01-01

To determine the issue of whether there were any significant differences between the groups including Iran ISI, Iran non- ISI, and native authors in binary comparisons as for employing interactional markers, the present study was conducted. To collect the data, 90 "method sections" of English medical research articles within Iranian ISI,…

Phosphorothioate oligonucleotides inhibit the intrinsic tenase complex.

PubMed

Sheehan, J P; Lan, H C

1998-09-01

Systemic administration of ISIS 2302, a 20-mer antisense phosphorothioate oligonucleotide targeting human intercellular adhesion molecule-1 mRNA, causes prolongation of plasma clotting times in both monkey and human studies. The anticoagulant effects of ISIS 2302 were investigated with both in vitro coagulation assays in human plasma and purified enzyme systems. At high oligonucleotide plasma concentrations (>100 microgram/mL), prolongation of the prothrombin and thrombin times was observed. In a thrombin time assay using purified components, high concentrations of ISIS 2302 inhibited thrombin clotting activity both by stimulating inhibition by heparin cofactor II and directly competing with fibrinogen for binding to anion binding exosite I. In contrast, low concentrations of ISIS 2302 (<100 microgram/mL) showed a selective, linear prolongation of the activated partial thromboplastin time (PTT). The rate limiting effect of 50 microgram/mL ISIS 2302, which prolonged the PTT to 1.5 times control, was identified by sequential modification of the clotting assay. Delaying addition of oligonucleotide until after contact activation failed to correct prolongation of the PTT. The calcium-dependent steps of the intrinsic pathway were individually assessed by adding sufficient activated coagulation factor to correct the PTT in plasma deficient in that specific factor. Addition of factor XIa, IXa, VIIIa, or Va failed to correct the PTT in the presence of ISIS 2302. In contrast, 0.2 nmol/L factor Xa corrected prolongation of the PTT in factor X-deficient plasma with or without oligonucleotide present. ISIS 2302 (50 microgram/mL) did not prolong a modified Russel viper venom time, suggesting no significant inhibition of prothrombinase. Thus, 50 microgram/mL ISIS 2302 prolonged the PTT by selectively inhibiting intrinsic tenase activity. ISIS 2302 showed partial inhibition of intrinsic tenase activity (to approximately 35% of control) at clinically relevant oligonucleotide concentrations in a chromogenic assay. This activity was oligonucleotide sequence-independent but required the phosphorothioate backbone, suggesting that inhibition of intrinsic tenase is a general property of this class of oligonucleotides. These results are relevant to both the therapeutic use of phosphorothioate oligonucleotides and the potential design of inhibitors of the intrinsic tenase complex, a novel target for anticoagulation. Copyright 1998 by The American Society of Hematology.

Host location and host discrimination behavior of Telenomus isis, an egg parasitoid of the African cereal stem borer Sesamia calamistis.

PubMed

Chabi-Olaye, A; Schulthess, F; Poehling, H M; Borgemeister, C

2001-04-01

In the Republic of Benin, the scelionid egg parasitoid Telenomus isis (Polaszek) is one of the most important control factors of the noctuid maize stem borer Sesamia calamistis. In the present study, the role of various sources of contact kairomones (male or virgin or mated female moths) and of the moth's oviposition substrate (leaf sheath versus filter paper: host plant species) in host location and oviposition behavior of T. isis was investigated in Munger cells, open arenas, and/or Petri dish assays. Furthermore, its ability to distinguish between unparasitized eggs and eggs parasitized by a conspecific female or by the trichogrammatid Lathromeris ovicida was studied. In the Munger cell experiment, T. isis spent more time in moths' odor fields than in the control. There was no difference between virgin and mated females. In the open arena assay, traces left by both the male and female moths acted as contact cues, which elicited an arrestment response in the parasitoid. The residence and patch retention time in the arena with virgin or mated females of S. calamistis was about 4.8 times as long as that with males. The presence of maize leaf sheaths stimulated the oviposition behavior of T. isis when compared to eggs offered on filter paper. During the first 6 hr, more eggs were parasitized on maize leaves, although there was no difference in the final number of offspring between the two substrates. In addition, if eggs of S. calamistis were offered together with different host plant species or alone, maize and sorghum were both more attractive than millet or the egg alone and equally attractive between themselves, indicating that the plant tissue influences host finding of T. isis. Both T. isis and L. ovicida recognized markings of conspecific females, and intraspecific superparasitism was therefore low. Interspecific superparasitism was more than three times higher for L. ovicida than for T. isis, indicating that only T. isis was able to recognize the marking of the other species and tried to avoid superparasitism. Emergence of parasitoids from multiparasitized eggs generally was in favor of L. ovicida regardless of species order.

Intervention for bilingual speech sound disorders: A case study of an isiXhosa-English-speaking child.

PubMed

Rossouw, Kate; Pascoe, Michelle

2018-03-19

 Bilingualism is common in South Africa, with many children acquiring isiXhosa as a home language and learning English from a young age in nursery or crèche. IsiXhosa is a local language, part of the Bantu language family, widely spoken in the country. Aims: To describe changes in a bilingual child's speech following intervention based on a theoretically motivated and tailored intervention plan. Methods and procedures: This study describes a female isiXhosa-English bilingual child, named Gcobisa (pseudonym) (chronological age 4 years and 2 months) with a speech sound disorder. Gcobisa's speech was assessed and her difficulties categorised according to Dodd's (2005) diagnostic framework. From this, intervention was planned and the language of intervention was selected. Following intervention, Gcobisa's speech was reassessed. Outcomes and results: Gcobisa's speech was categorised as a consistent phonological delay as she presented with gliding of/l/in both English and isiXhosa, cluster reduction in English and several other age appropriate phonological processes. She was provided with 16 sessions of intervention using a minimal pairs approach, targeting the phonological process of gliding of/l/, which was not considered age appropriate for Gcobisa in isiXhosa when compared to the small set of normative data regarding monolingual isiXhosa development. As a result, the targets and stimuli were in isiXhosa while the main language of instruction was English. This reflects the language mismatch often faced by speech language therapists in South Africa. Gcobisa showed evidence of generalising the target phoneme to English words. Conclusions and implications: The data have theoretical implications regarding bilingual development of isiXhosa-English, as it highlights the ways bilingual development may differ from the monolingual development of this language pair. It adds to the small set of intervention studies investigating the changes in the speech of bilingual children following intervention. In addition, it contributes to the small amount of data gathered regarding typical bilingual acquisition of this language pair.

Defense Data Network/TOPS-20 Tutorial. An Interative Computer Program.

DTIC Science & Technology

1985-12-01

33 XI. ELECTRONIC MAIL HOST ( EMH )-------------------------- 34 XII. EMACS...contents of text buffer to a file X EXCHANGE , used to search for and replace text Z ZAP, puts your entire file into the print buffer 23 - -° SWITCH...prompt USC-ISIE.ARPA> Sample foreign host command level prompt FTP COMMAND LEVEL COMMANDS COMMAND USE(S) FTP Invokes the FTP protocol CONNECT Connects

Museums, Zoos, and Gardens: How Formal-Informal Partnerships Can Impact Urban Students' Performance. Working Paper #04-13

ERIC Educational Resources Information Center

Weinstein, Meryle; Whitesell, Emilyn Ruble; Schwartz, Amy Ellen

2013-01-01

In this paper we provide the first rigorous evidence of the impact of a partnership between public middle schools and informal science institutions (ISIs), such as museums and zoos, on student outcomes. This study focuses on Urban Advantage (UA), a program in New York City (NYC) that explicitly draws upon the expertise and resources of the city's…

A Research Program in Computer Technology. 1982 Annual Technical Report

DTIC Science & Technology

1983-03-01

for the Defense Advanced Research Projects Agency. The research applies computer science and technology to areas of high DoD/ military impact. The ISI...implement the plan; New Computing Environment - investigation and adaptation of developing computer technologies to serve the research and military ...Computing Environment - ,.*_i;.;"’.)n and adaptation of developing computer technologies to serve the research and military tser communities; and Computer

DE/ISIS conjunction comparisons of high-latitude electron density features

NASA Technical Reports Server (NTRS)

Hoegy, Walter R.; Benson, Robert F.

1988-01-01

This paper presents a comparison between the ISIS-1 and -2 topside sounder measurements of electron number density, N(e), with the in situ ion and N(e) measurements by the Langmuir probe aboard the Dynamics Explorer 2 (DE 2) during four high-latitude ISIS/DE magnetic field-aligned conjunctions. The ISIS-derived N(e) values, even at the greatest distance from the sounder, were found to agree with the Langmuir probe measurements to within about 30 percent over a density range of more than two decades on three of the four comparisons; the fourth comparison which included data with strong N(e) irregularities, showed a difference of 60 percent.

Literature and best practices scan : Vehicle Inspection and Maintenance (I/M) Programs

DOT National Transportation Integrated Search

2002-06-01

The state of Wisconsin operates one of the nation's most effective inspection/maintenance (I/M) programs. In Wisconsin's I/M program, vehicles registered in the Milwaukee metropolitan area are subjected to a transient emission test using the IM240 te...

Precluding nonlinear ISI in direct detection long-haul fiber optic systems

NASA Technical Reports Server (NTRS)

Swenson, Norman L.; Shoop, Barry L.; Cioffi, John M.

1991-01-01

Long-distance, high-rate fiber optic systems employing directly modulated 1.55-micron single-mode lasers and conventional single-mode fiber suffer severe intersymbol interference (ISI) with a large nonlinear component. A method of reducing the nonlinearity of the ISI, thereby making linear equalization more viable, is investigated. It is shown that the degree of nonlinearity is highly dependent on the choice of laser bias current, and that in some cases the ISI nonlinearity can be significantly reduced by biasing the laser substantially above threshold. Simulation results predict that an increase in signal-to-nonlinear-distortion ratio as high as 25 dB can be achieved for synchronously spaced samples at an optimal sampling phase by increasing the bias current from 1.2 times threshold to 3.5 times threshold. The high SDR indicates that a linear tapped delay line equalizer could be used to mitigate ISI. Furthermore, the shape of the pulse response suggests that partial response precoding and digital feedback equalization would be particularly effective for this channel.

Organizing knowledge in the Isis bibliography from Sarton to the early twenty-first century.

PubMed

Weldon, Stephen P

2013-09-01

This essay explores various ways in which bibliographies have exhibited "sociality." Bibliographies are both products of the social contexts that have created them and engines of social interaction in scholarly communities. By tracing the history of the Isis Bibliography, the longest-running and most comprehensive bibliography in its field, this essay explains how different Isis classification systems have been tied to major twentieth-century cataloging efforts. By looking at classification, the essay also attends to the ways in which aspects of the Isis Bibliography in different decades have reflected social mores of their period. Finally, it demonstrates how critical the Isis Bibliography was in the formation of the discipline of history of science and goes on to discuss how that disciplinary connection is evolving in the twenty-first century. By thinking of the bibliography as a network of scholars, not just scholarly works, the essay asks us to reflect on the nature and purpose of bibliography in the digital age.

Analysis of noise-induced temporal correlations in neuronal spike sequences

NASA Astrophysics Data System (ADS)

Reinoso, José A.; Torrent, M. C.; Masoller, Cristina

2016-11-01

We investigate temporal correlations in sequences of noise-induced neuronal spikes, using a symbolic method of time-series analysis. We focus on the sequence of time-intervals between consecutive spikes (inter-spike-intervals, ISIs). The analysis method, known as ordinal analysis, transforms the ISI sequence into a sequence of ordinal patterns (OPs), which are defined in terms of the relative ordering of consecutive ISIs. The ISI sequences are obtained from extensive simulations of two neuron models (FitzHugh-Nagumo, FHN, and integrate-and-fire, IF), with correlated noise. We find that, as the noise strength increases, temporal order gradually emerges, revealed by the existence of more frequent ordinal patterns in the ISI sequence. While in the FHN model the most frequent OP depends on the noise strength, in the IF model it is independent of the noise strength. In both models, the correlation time of the noise affects the OP probabilities but does not modify the most probable pattern.

23 CFR 650.313 - Inspection procedures.

Code of Federal Regulations, 2010 CFR

2010-04-01

...) Quality control and quality assurance. Assure systematic quality control (QC) and quality assurance (QA... periodic field review of inspection teams, periodic bridge inspection refresher training for program managers and team leaders, and independent review of inspection reports and computations. (h) Follow-up on...

24 CFR 5.705 - Uniform physical inspection requirements.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 1 2014-04-01 2014-04-01 false Uniform physical inspection... and Urban Development GENERAL HUD PROGRAM REQUIREMENTS; WAIVERS Physical Condition Standards and Inspection Requirements § 5.705 Uniform physical inspection requirements. Any entity responsible for...

24 CFR 5.705 - Uniform physical inspection requirements.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 1 2013-04-01 2013-04-01 false Uniform physical inspection... and Urban Development GENERAL HUD PROGRAM REQUIREMENTS; WAIVERS Physical Condition Standards and Inspection Requirements § 5.705 Uniform physical inspection requirements. Any entity responsible for...

24 CFR 5.705 - Uniform physical inspection requirements.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 1 2011-04-01 2011-04-01 false Uniform physical inspection... and Urban Development GENERAL HUD PROGRAM REQUIREMENTS; WAIVERS Physical Condition Standards and Inspection Requirements § 5.705 Uniform physical inspection requirements. Any entity responsible for...

24 CFR 5.705 - Uniform physical inspection requirements.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 1 2012-04-01 2012-04-01 false Uniform physical inspection... and Urban Development GENERAL HUD PROGRAM REQUIREMENTS; WAIVERS Physical Condition Standards and Inspection Requirements § 5.705 Uniform physical inspection requirements. Any entity responsible for...

24 CFR 5.705 - Uniform physical inspection requirements.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Uniform physical inspection... and Urban Development GENERAL HUD PROGRAM REQUIREMENTS; WAIVERS Physical Condition Standards and Inspection Requirements § 5.705 Uniform physical inspection requirements. Any entity responsible for...

Measuring multiple spike train synchrony.

PubMed

Kreuz, Thomas; Chicharro, Daniel; Andrzejak, Ralph G; Haas, Julie S; Abarbanel, Henry D I

2009-10-15

Measures of multiple spike train synchrony are essential in order to study issues such as spike timing reliability, network synchronization, and neuronal coding. These measures can broadly be divided in multivariate measures and averages over bivariate measures. One of the most recent bivariate approaches, the ISI-distance, employs the ratio of instantaneous interspike intervals (ISIs). In this study we propose two extensions of the ISI-distance, the straightforward averaged bivariate ISI-distance and the multivariate ISI-diversity based on the coefficient of variation. Like the original measure these extensions combine many properties desirable in applications to real data. In particular, they are parameter-free, time scale independent, and easy to visualize in a time-resolved manner, as we illustrate with in vitro recordings from a cortical neuron. Using a simulated network of Hindemarsh-Rose neurons as a controlled configuration we compare the performance of our methods in distinguishing different levels of multi-neuron spike train synchrony to the performance of six other previously published measures. We show and explain why the averaged bivariate measures perform better than the multivariate ones and why the multivariate ISI-diversity is the best performer among the multivariate methods. Finally, in a comparison against standard methods that rely on moving window estimates, we use single-unit monkey data to demonstrate the advantages of the instantaneous nature of our methods.

9 CFR 352.18 - Cooperation of States in Federal programs.

Code of Federal Regulations, 2010 CFR

2010-01-01

... OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION EXOTIC ANIMALS AND HORSES; VOLUNTARY INSPECTION Exotic...

The influence of prior experience and expected timing on vibrotactile discrimination

PubMed Central

Karim, Muhsin; Harris, Justin A.; Langdon, Angela; Breakspear, Michael

2013-01-01

Vibrotactile discrimination tasks involve perceptual judgements on stimulus pairs separated by a brief interstimulus interval (ISI). Despite their apparent simplicity, decision making during these tasks is biased by prior experience in a manner that is not well understood. A striking example is when participants perform well on trials where the first stimulus is closer to the mean of the stimulus-set than the second stimulus, and perform comparatively poorly when the first stimulus is further from the stimulus mean. This “time-order effect” suggests that participants implicitly encode the mean of the stimulus-set and use this internal standard to bias decisions on any given trial. For relatively short ISIs, the magnitude of the time-order effect typically increases with the distance of the first stimulus from the global mean. Working from the premise that the time-order effect reflects the loss of precision in working memory representations, we predicted that the influence of the time-order effect, and this superimposed “distance” effect, would monotonically increase for trials with longer ISIs. However, by varying the ISI across four intervals (300, 600, 1200, and 2400 ms) we instead found a complex, non-linear dependence of the time-order effect on both the ISI and the distance, with the time-order effect being paradoxically stronger at short ISIs. We also found that this relationship depended strongly on participants' prior experience of the ISI (from previous task titration). The time-order effect not only depends on participants' expectations concerning the distribution of stimuli, but also on the expected timing of the trials. PMID:24399927

Phase I study of the c-raf-1 antisense oligonucleotide ISIS 5132 in combination with carboplatin and paclitaxel in patients with previously untreated, advanced non-small cell lung cancer.

PubMed

Fidias, Panos; Pennell, Nathan A; Boral, Anthony L; Shapiro, Geoffrey I; Skarin, Arthur T; Eder, Joseph P; Kwoh, T Jesse; Geary, Richard S; Johnson, Bruce E; Lynch, Thomas J; Supko, Jeffrey G

2009-09-01

A phase I trial was performed to evaluate the administration of carboplatin/paclitaxel in combination with ISIS-5132, a phosphorothioate antisense oligodeoxynucleotide inhibitor of c-raf-1 kinase expression, in patients with advanced non-small cell lung cancer (NSCLC). Previously untreated patients with stage IIIB/IV NSCLC received ISIS 5132 by continuous intravenous infusion at 2.0 mg/kg/d for 14 days. Starting doses were paclitaxel 175 mg/m(2) and carboplatin targeting an area under the free platinum plasma concentration-time curve (AUC(fp)) of 5 mg . min/ml (dose level 1). The carboplatin dose was then increased to AUC(fp) 6 mg . min/ml (dose level 2) after which the paclitaxel dose was increased to 200 mg/m(2) (dose level 3). The maximum tolerated dose was established by toxicity during the first two 21-day cycles of therapy. The pharmacokinetics of all three agents was determined before and during the ISIS 5132 infusion. Thirteen patients were treated with the carboplatin/paclitaxel/ISIS 5132 combination. Dose-limiting neutropenia occurred in two patients at dose level 3. Grade 3 and 4 nonhematologic toxicities were infrequent and limited to nausea and constipation. The maximum tolerated doses were carboplatin AUC(fp) 6 mg . min/ml, paclitaxel 175 mg/m(2), and ISIS 5132 2.0 mg/kg/d for 14 days. There were no objective responses and the concurrent infusion of ISIS 5132 did not alter the plasma pharmacokinetics of paclitaxel or total platinum. ISIS 5132 can be safely combined with standard doses of carboplatin and paclitaxel. Combining cytotoxic chemotherapeutic agents with inhibitors of aberrant signal transduction mediated by Raf proteins produced no objective responses in the dose and schedule administered in this study.

A Phase I, Randomised, First-in-Human Study of an Antisense Oligonucleotide Directed Against SOD1 Delivered Intrathecally in SOD1-Familial ALS Patients

PubMed Central

Miller, Timothy; Pestronk, Alan; David, William; Rothstein, Jeffrey; Simpson, Ericka; Appel, Stanley H.; Andres, Patricia L.; Mahoney, Katy; Allred, Peggy; Alexander, Katie; Ostrow, Lyle W.; Schoenfeld, David; Macklin, Eric A.; Norris, Daniel A.; Manousakis, Georgios; Crisp, Matthew; Smith, Richard; Bennett, C.F.; Bishop, Kathie; Cudkowicz, Merit E

2013-01-01

Objective To evaluate the safety, tolerability, and pharmacokinetics of an antisense oligonucleotide designed to inhibit SOD1 expression (ISIS 333611) following intrathecal administration in patients with SOD1-related familial amyotrophic lateral sclerosis (ALS). Background Mutations in SOD1 cause 13% of familial ALS. In animal studies, ISIS 333611 delivered to the cerebrospinal fluid (CSF) distributed to the brain and spinal cord, decreased SOD1 mRNA and protein levels in spinal cord tissue, and prolonged survival in the SOD1G93A rat ALS model. Methods In a randomized, placebo controlled Phase 1 trial, ISIS 333611 was delivered by intrathecal infusion using an external pump over 11.5 hours at increasing doses to four cohorts of eight SOD1 positive ALS subjects (randomized 6 drug: 2 placebo/cohort). Subjects were allowed to re-enroll in subsequent cohorts. Safety and tolerability assessments were made during the infusion and periodically over 28 days following the infusion. CSF and plasma drug levels were measured. Findings No dose-limiting toxicities were identified at doses up to 3.0 mg. No safety or tolerability concerns related to ISIS 333611 were identified. There were no serious adverse events (AEs) in ISIS 333611-treated subjects. Re-enrollment and re-dosing of subjects with ISIS 333611 was also well tolerated. Dose-dependent CSF and plasma concentrations were observed. Interpretation In this first clinical study to report intrathecal delivery of an antisense oligonucleotide, ISIS 333611 was well tolerated when administered as an intrathecal infusion in subjects with SOD1 familial ALS. CSF and plasma drug levels were consistent with levels predicted from preclinical studies. These results suggest that antisense oligonucleotide delivery to the central nervous system may be a feasible therapeutic strategy for neurological disorders. Source of funding ALS Association, Muscular Dystrophy Association, Isis Pharmaceuticals PMID:23541756

Evaluation of overhead support inspection program.

DOT National Transportation Integrated Search

2015-01-01

This study evaluated the adequacy and frequency of the current structural support inspection program for overhead : sign supports (including bridge mounted), mast arm signal supports and high mast light supports. While ODOT provides : statewide guida...

49 CFR 40.107 - Who may inspect laboratories?

Code of Federal Regulations, 2010 CFR

2010-10-01

... DRUG AND ALCOHOL TESTING PROGRAMS Drug Testing Laboratories § 40.107 Who may inspect laboratories? As a...-regulated employer that contracts with the laboratory for drug testing under the DOT drug testing program...

49 CFR 40.107 - Who may inspect laboratories?

Code of Federal Regulations, 2012 CFR

2012-10-01

... DRUG AND ALCOHOL TESTING PROGRAMS Drug Testing Laboratories § 40.107 Who may inspect laboratories? As a...-regulated employer that contracts with the laboratory for drug testing under the DOT drug testing program...

49 CFR 40.107 - Who may inspect laboratories?

Code of Federal Regulations, 2014 CFR

2014-10-01

... DRUG AND ALCOHOL TESTING PROGRAMS Drug Testing Laboratories § 40.107 Who may inspect laboratories? As a...-regulated employer that contracts with the laboratory for drug testing under the DOT drug testing program...

49 CFR 40.107 - Who may inspect laboratories?

Code of Federal Regulations, 2013 CFR

2013-10-01

... DRUG AND ALCOHOL TESTING PROGRAMS Drug Testing Laboratories § 40.107 Who may inspect laboratories? As a...-regulated employer that contracts with the laboratory for drug testing under the DOT drug testing program...

49 CFR 40.107 - Who may inspect laboratories?

Code of Federal Regulations, 2011 CFR

2011-10-01

... DRUG AND ALCOHOL TESTING PROGRAMS Drug Testing Laboratories § 40.107 Who may inspect laboratories? As a...-regulated employer that contracts with the laboratory for drug testing under the DOT drug testing program...

42 CFR 456.607 - Notification before inspection.

Code of Federal Regulations, 2010 CFR

2010-10-01

... (CONTINUED) MEDICAL ASSISTANCE PROGRAMS UTILIZATION CONTROL Inspections of Care in Intermediate Care Facilities and Institutions for Mental Diseases § 456.607 Notification before inspection. No facility may be...

7 CFR 205.403 - On-site inspections.

Code of Federal Regulations, 2010 CFR

2010-01-01

..., Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) ORGANIC FOODS PRODUCTION ACT PROVISIONS NATIONAL ORGANIC PROGRAM Certification § 205.403 On-site inspections. (a) On-site inspections. (1... site that produces or handles organic products and that is included in an operation for which...

7 CFR 205.403 - On-site inspections.

Code of Federal Regulations, 2012 CFR

2012-01-01

..., Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) ORGANIC FOODS PRODUCTION ACT PROVISIONS NATIONAL ORGANIC PROGRAM Certification § 205.403 On-site inspections. (a) On-site inspections. (1... site that produces or handles organic products and that is included in an operation for which...

7 CFR 205.403 - On-site inspections.

Code of Federal Regulations, 2013 CFR

2013-01-01

..., Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) ORGANIC FOODS PRODUCTION ACT PROVISIONS NATIONAL ORGANIC PROGRAM Certification § 205.403 On-site inspections. (a) On-site inspections. (1... site that produces or handles organic products and that is included in an operation for which...

7 CFR 205.403 - On-site inspections.

Code of Federal Regulations, 2014 CFR

2014-01-01

..., Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) ORGANIC FOODS PRODUCTION ACT PROVISIONS NATIONAL ORGANIC PROGRAM Certification § 205.403 On-site inspections. (a) On-site inspections. (1... site that produces or handles organic products and that is included in an operation for which...

7 CFR 205.403 - On-site inspections.

Code of Federal Regulations, 2011 CFR

2011-01-01

..., Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) ORGANIC FOODS PRODUCTION ACT PROVISIONS NATIONAL ORGANIC PROGRAM Certification § 205.403 On-site inspections. (a) On-site inspections. (1... site that produces or handles organic products and that is included in an operation for which...

National Dam Safety Program. Brocton Reservoir (Inventory Number NY 785) , Lake Erie Basin, Chautauqua County, New York. Phase I Inspection Report

DTIC Science & Technology

1980-09-26

Inspection Report Brocton Reservoir National Dam Safety Program Lake Erie Basin, Chautauqua County, New York 6. PERFORMING ORG. REPORT NUMBER Inventory No...LAKE ERIE BASIN BROCTON RESERVOIR I ’CHAUTAUQUA COUNTY, NEW YORK I INVENTORY NO. N.Y. 785 PHASE I INSPECTION REPORT NATIONAL DAM SAFETY PROGRAMI. I...Drawings I I I I I I I I I I PHASE I INSPECTION REPORT NATIONAL DAM SAFETY PROGRAIM NAME OF DAM: Brocton Reservoir Inventory No. N.Y. 785 I STATE LOCATED

National Program of Inspection of Dams. Volume 1. Report of the Chief of Engineers on the National Program of Inspection of Dams. Appendices A-D

DTIC Science & Technology

1975-05-01

legislation, but thus far it has not become possible due to certain limitations of economic nature. Up to now the inspection and mainte- nance of...Principally, this is due to the lack of funds and staff to perform inspection duties. It is apparent that increased activity in the regulation of the...conduct an investigation. Yes. Nothing formal , upon complaint or upon its own initiative, the Department has power to cause an investigation or

National Dam Safety Program. Cadet Mine Tailings Dam (MO 30715), Mississippi - Kaskaskia - St. Louis Basin, Washington County, Missouri. Phase I Inspection Report.

DTIC Science & Technology

1980-02-01

Safety Inspection of Dams" are not available. These studies should be performed by a professional engineer experienced in the design and construction...engineer experienced in the design and construction of tailings dams. An inspection and maintenance program should be initiated. Periodic inspections...Page No. SECTION 1 - PROJECT INFORMATION 1.1 General 1 1.2 Description of Project 1 1.3 Pertinent Data 2 SECTION 2 - ENGINEERING DATA 2.1 Design 5 2.2

National Program for Inspection of Non-Federal Dams. Bristol Reservoir Number 5 Dam (CT 00366), Farmington River Basin, Harwinton, Connecticut. Phase I Inspection Report.

DTIC Science & Technology

1980-07-01

age control and/or monitoring measures as needed. 2. Investigate the condition of the corrugated metal outlet pipe and make any necessary repairs. 3...BACKGROUND. USARMY ENGINEER DIV NEW ENGLAND BRISTOL RES. NO. 5 DAM Coll O .ENIER NATIONAL PROGRAM OF TR. TO POLAND R IVER WALTHAM ! ASCUE INSPECTION

Impact of a Letter-Grade Program on Restaurant Sanitary Conditions and Diner Behavior in New York City

PubMed Central

McKelvey, Wendy; Ito, Kazuhiko; Schiff, Corinne; Jacobson, J. Bryan; Kass, Daniel

2015-01-01

Objectives. We evaluated the impact of the New York City restaurant letter-grading program on restaurant hygiene, food safety practices, and public awareness. Methods. We analyzed data from 43 448 restaurants inspected between 2007 and 2013 to measure changes in inspection score and violation citations since program launch in July 2010. We used binomial regression to assess probability of scoring 0 to 13 points (A-range score). Two population-based random-digit-dial telephone surveys assessed public perceptions of the program. Results. After we controlled for repeated restaurant observations, season of inspection, and chain restaurant status, the probability of scoring 0 to 13 points on an unannounced inspection increased 35% (95% confidence interval [CI] = 31%, 40%) 3 years after compared with 3 years before grading. There were notable improvements in compliance with some specific requirements, including having a certified kitchen manager on site and being pest-free. More than 91% (95% CI = 88%, 94%) of New Yorkers approved of the program and 88% (95% CI = 85%, 92%) considered grades in dining decisions in 2012. Conclusions. Restaurant letter grading in New York City has resulted in improved sanitary conditions on unannounced inspection, suggesting that the program is an effective regulatory tool. PMID:25602861

40 CFR 52.786 - Inspection and maintenance program.

Code of Federal Regulations, 2011 CFR

2011-07-01

..., commitment to timely adopt and implement enhanced inspection and maintenance (I/M) rules for Lake and Porter... parts of the program to certify compliance. (e) After July 1, 1976, the State of Indiana, County of... pertaining to the development and adoption of necessary authority for the I/M program. This disapproval...

40 CFR 52.786 - Inspection and maintenance program.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., commitment to timely adopt and implement enhanced inspection and maintenance (I/M) rules for Lake and Porter... parts of the program to certify compliance. (e) After July 1, 1976, the State of Indiana, County of... pertaining to the development and adoption of necessary authority for the I/M program. This disapproval...

42 CFR 456.606 - Frequency of inspections.

Code of Federal Regulations, 2010 CFR

2010-10-01

... (CONTINUED) MEDICAL ASSISTANCE PROGRAMS UTILIZATION CONTROL Inspections of Care in Intermediate Care Facilities and Institutions for Mental Diseases § 456.606 Frequency of inspections. The team and the agency...

42 CFR 456.614 - Inspections by utilization review committee.

Code of Federal Regulations, 2010 CFR

2010-10-01

... HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS UTILIZATION CONTROL Inspections of Care in Intermediate Care Facilities and Institutions for Mental Diseases § 456.614 Inspections by utilization review...

"Unomathotholo" or "i-Radio?" Factors Predicting the Use of English Loanwords among L1 isiXhosa--L2 English Bilinguals

ERIC Educational Resources Information Center

Bylund, Emanuel

2014-01-01

This study examines the use of English loanwords in L1 isiXhosa-L2 English bilinguals living in Cape Town, South Africa. The specific aim of the study is to investigate which individual background factors may increase or reduce the presence of English loanwords in a L1 isiXhosa speaker's repertoire. Data on English loanword use and individual…

49 CFR 237.103 - Bridge inspection procedures.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Bridge inspection procedures. 237.103 Section 237... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION BRIDGE SAFETY STANDARDS Bridge Inspection § 237.103 Bridge inspection procedures. (a) Each bridge management program shall specify the procedure to be used for...

49 CFR 237.101 - Scheduling of bridge inspections.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Scheduling of bridge inspections. 237.101 Section... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION BRIDGE SAFETY STANDARDS Bridge Inspection § 237.101 Scheduling of bridge inspections. (a) Each bridge management program shall include a provision for scheduling an...

49 CFR 237.101 - Scheduling of bridge inspections.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Scheduling of bridge inspections. 237.101 Section... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION BRIDGE SAFETY STANDARDS Bridge Inspection § 237.101 Scheduling of bridge inspections. (a) Each bridge management program shall include a provision for scheduling an...

49 CFR 237.103 - Bridge inspection procedures.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Bridge inspection procedures. 237.103 Section 237... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION BRIDGE SAFETY STANDARDS Bridge Inspection § 237.103 Bridge inspection procedures. (a) Each bridge management program shall specify the procedure to be used for...

40 CFR 51.367 - Inspector training and licensing or certification.

Code of Federal Regulations, 2010 CFR

2010-07-01

...) Public relations; and (ix) Safety and health issues related to the inspection process. (2) If inspector... effects; (ii) The purpose, function, and goal of the inspection program; (iii) Inspection regulations and... control device function, configuration, and inspection; (vi) Test equipment operation, calibration, and...

42 CFR 456.611 - Reports on inspections.

Code of Federal Regulations, 2010 CFR

2010-10-01

... (CONTINUED) MEDICAL ASSISTANCE PROGRAMS UTILIZATION CONTROL Inspections of Care in Intermediate Care Facilities and Institutions for Mental Diseases § 456.611 Reports on inspections. (a) The team must submit a...

Assisting New York Dairy Farms with Preparing for OSHA Safety Inspections.

PubMed

Tinc, Pamela J; Carrabba, Jim; Meyerhoff, Anna; Horsman, Melissa

2018-01-01

In 2013, the Occupational Safety and Health Administration announced a Local Emphasis Program targeted at New York farmers. This program involved random inspections of dairy farms across the state. This article provides an overview of the efforts made in New York to prepare farmers for these inspections. As a result of this program launch, several safety services offered by the New York Center for Agricultural Medicine and Health were significantly impacted, and required expansion and modification in order to meet the needs of New York farmers.

National Dam Safety Program. Ursel Gingerich Dam (MO 10393), Mississippi - Salt - Quincy River Basin, Schuyler County, Missouri. Phase I Inspection Report.

DTIC Science & Technology

1979-12-01

34 which identifies the program element, project, task area, and work unit or equivalent under which the work was authorized. Block 11. Controlling ...Dam Inventory and Inspection Section, LMSED-PD ULSF 210 Tucker Blvd., North, St. Louis, Mo. 63101D C O 11. CONTROLLING OFFICE NAME AND ADDRESS 12m...under the National Program of Inspection of Non -Federal Dams. This report assesses the general condition of the dam with a respect to safety, based on

Scenarios and performance measures for advanced ISDN satellite design and experiments

NASA Technical Reports Server (NTRS)

Pepin, Gerard R.

1991-01-01

Described here are the contemplated input and expected output for the Interim Service Integrated Services Digital Network (ISDN) Satellite (ISIS) and Full Service ISDN Satellite (FSIS) Models. The discrete event simulations of these models are presented with specific scenarios that stress ISDN satellite parameters. Performance measure criteria are presented for evaluating the advanced ISDN communication satellite designs of the NASA Satellite Communications Research (SCAR) Program.

Designing application software in wide area network settings

NASA Technical Reports Server (NTRS)

Makpangou, Mesaac; Birman, Ken

1990-01-01

Progress in methodologies for developing robust local area network software has not been matched by similar results for wide area settings. The design of application software spanning multiple local area environments is examined. For important classes of applications, simple design techniques are presented that yield fault tolerant wide area programs. An implementation of these techniques as a set of tools for use within the ISIS system is described.

Integrated System Safety Program for the MX Weapon System.

DTIC Science & Technology

1979-09-25

Quantitative AnalIsis Of Specified Undesired Events Nuclr Safey Anisis Reports ISARI Contractor Inpu To AFWL Technical Nucler Sa An. Is FIGURE 1...Launch Includes all functions from initiation of launch se- quence to missile first motion, such as transfer from ground power to airborne power ...all credible contingency or emergency condi- tions, such as Toxic gases/fluid release, inadvertently armed ordnance, electric power loss, and destruct

Development of the Macro Command Editing Executive System for Factory Workers-Oriented Programless Visual Inspection System

NASA Astrophysics Data System (ADS)

Anezaki, Takashi; Wakitani, Kouichi; Nakamura, Masatoshi; Kubo, Hiroyasu

Because visual inspection systems are difficult to tune, they create many problems for the kaizen process. This results in increased development costs and time to assure that the inspection systems function properly. In order to improve inspection system development, we designed an easy-tuning system called a “Program-less” visual inspection system. The ROI macro command which consisted of eight kinds of shape recognition macro commands and decision, operation, control commands was built. Furthermore, the macro command editing executive system was developed by the operation of only the GUI without editing source program. The validity of the ROI macro command was proved by the application of 488 places.

Methodological aspects of a GIS-based environmental health inspection program used in the Athens 2004 Olympic and Para Olympic Games.

PubMed

Hadjichristodoulou, Christos; Soteriades, Elpidoforos S; Kolonia, Virginia; Falagas, Matthew E; Pantelopoulos, Efstathios; Panagakos, Georgios; Mouchtouri, Varvara; Kremastinou, Jeni

2005-09-02

The use of geographical information system (GIS) technologies in public health surveillance is gradually gaining momentum around the world and many applications have already been reported in the literature. In this study, GIS technology was used to help county departments of Public Health to implement environmental health surveillance for the Athens 2004 Olympic and Para Olympic Games. In order to assess the workload in each Olympic county, 19 registry forms and 17 standardized inspection forms were developed to register and inspect environmental health items requiring inspection (Hotels, restaurants, swimming pools, water supply system etc), respectively. Furthermore, related databases were created using Epi Info 2002 and a geographical information system (GIS) were used to implement an integrated Environmental Health inspection program. The project was conducted in Athens by the Olympic Planning Unit (OPU) of the National School of Public Health, in close cooperation with the Ministry of Health and Social Solidarity and the corresponding departments of Public Health in all municipalities that were scheduled to host events during the Athens 2004 Olympic and Para Olympic games. A total of 44,741 premises of environmental health interest were geocoded into GIS databases and several electronic maps were developed. Using such maps in association with specific criteria, we first identified the maximum workload required to execute environmental health inspections in all premises within the eleven Olympic County Departments of Public Health. Six different scenarios were created for each county, based on devised algorithms in order to design the most effective and realistic inspection program using the available inspectors from each municipality. Furthermore, GIS applications were used to organize the daily inspection program for the Olympic games, provide coloured displays of the inspection results and link those results with the public health surveillance of specific cases or outbreak investigation. Our computerised program exhibited significant efficiency in facilitating the prudent use of public health resources in implementing environmental health inspections in densely populated urban areas as well as in rural counties. Furthermore, the application of simple algorithms in integrating human and other resources provided tailored and cost-effective applications to different public health agencies.

Use of two test methods to ensure accurate surface firmness and stability measurements for accessibility.

PubMed

Axelson, Peter W; Hurley, Seanna L

2018-05-01

The firmness and stability of indoor and outdoor surfacing are critical to the accessibility and safety of all environments for people with mobility impairments and/or who use mobility devices. ASTM F1951 laboratory test procedures include pass/fail criteria for determining playground surface accessibility by comparing the work to propel up a 1:14 (7.1%) grade ramp to that of the test surface in a wheelchair. A portable instrumented surface indenter (ISI) was developed to validate that accessibility results obtained in the laboratory are maintained in the field where the surface is installed and used. Accessibility measurements have been made on indoor and outdoor surfaces tested in the laboratory using both the ASTM F1951 and the ISI over 13 years. Correlations between these two methods were calculated. A strong correlation has been demonstrated for the sum of the ISI firmness and stability results compared to the sum of the ASTM F1951 straight propulsion and turning results (R 2 =0.9006). The portable ISI can be used to verify that the firmness and stability of an installed surface in the field correlates to the accessibility results of the surface tested in the laboratory concurrently according to ASTM F1951 and the ISI. Implications for Rehabilitation The Instrumented Surface Indenter (ISI) allows for surfaces in all environments to be tested for firmness and stability, which is critical for wheelchair user safety, especially during rehabilitation when learning to use a wheelchair. The ISI allows for surfaces in all environments to be tested for firmness and stability, which increases access to all indoor and outdoor surfaces, thereby improving the quality of life for people who have mobility impairments and/or use mobility devices, such as canes, crutches, walkers, and wheelchairs. Using the ISI to test the firmness and stability of installed playground surfaces increases access to playgrounds for children with mobility impairments, facilitating developmentally critical peer-play opportunities for children who use mobility devices. Using the ISI to test the firmness and stability of installed playground surfaces increases access to playgrounds for people with mobility impairments, allowing adults who use a mobility device to supervise and play with children in their lives.

Clean Air Act Section 112(r) Inspection Guidance Distribution Memorandum

EPA Pesticide Factsheets

This memorandum issues and makes immediately effective the document, Guidance for Conducting Risk Management Program Inspections under Clean Air Act Section 112(r), which supersedes the 1999 document on auditing risk management plans/programs.

Middle-aged, but not young, rats develop cognitive impairment and cortical neurodegeneration following the four-vessel occlusion/internal carotid artery model of chronic cerebral hypoperfusion.

PubMed

Ferreira, Emilene D Fiuza; Romanini, Cássia V; Mori, Marco A; de Oliveira, Rúbia M Weffort; Milani, Humberto

2011-10-01

Permanent, stepwise occlusion of the vertebral arteries (VAs) and internal carotid arteries (ICAs) following the sequence VA→ICA→ICA, with an interstage interval (ISI, →) of 7 days, has been investigated as a four-vessel occlusion (4-VO)/ICA model of chronic cerebral hypoperfusion. This model has the advantage of not causing retinal damage. In young rats, however, 4-VO/ICA with an ISI of 7 days fails to cause behavioral sequelae. We hypothesized that such a long ISI would allow the brain to efficiently compensate for cerebral hypoperfusion, preventing the occurrence of cognitive impairment and neurodegeneration. The present study evaluated whether brain neurodegeneration and learning/memory deficits can be expressed by reducing the length of the ISI and whether aging influences the outcome. Young, male Wistar rats were subjected to 4-VO/ICA with different ISIs (5, 4, 3 or 2 days). An ISI of 4 days was used in middle-aged rats. Ninety days after 4-VO/ICA, the rats were tested for learning/memory impairment in a modified radial maze and then examined for neurodegeneration of the hippocampus and cerebral cortex. Regardless of the ISI, young rats were not cognitively impaired, although hippocampal damage was evident. Learning/memory deficits and hippocampal and cortical neurodegeneration occurred in middle-aged rats. The data indicate that 4-VO/ICA has no impact on the capacity of young rats to learn the radial maze task, despite 51% hippocampal cell death. Such resistance is lost in middle-aged animals, for which the most extensive neurodegeneration observed in both the hippocampus and cerebral cortex may be responsible. © 2011 The Authors. European Journal of Neuroscience © 2011 Federation of European Neuroscience Societies and Blackwell Publishing Ltd.

Bone-breaking bite force of Basilosaurus isis (Mammalia, Cetacea) from the late Eocene of Egypt estimated by finite element analysis.

PubMed

Snively, Eric; Fahlke, Julia M; Welsh, Robert C

2015-01-01

Bite marks suggest that the late Eocence archaeocete whale Basilosaurus isis (Birket Qarun Formation, Egypt) fed upon juveniles of the contemporary basilosaurid Dorudon atrox. Finite element analysis (FEA) of a nearly complete adult cranium of B. isis enables estimates of its bite force and tests the animal's capabilities for crushing bone. Two loadcases reflect different biting scenarios: 1) an intitial closing phase, with all adductors active and a full condylar reaction force; and 2) a shearing phase, with the posterior temporalis active and minimized condylar force. The latter is considered probable when the jaws were nearly closed because the preserved jaws do not articulate as the molariform teeth come into occulusion. Reaction forces with all muscles active indicate that B. isis maintained relatively greater bite force anteriorly than seen in large crocodilians, and exerted a maximum bite force of at least 16,400 N at its upper P3. Under the shearing scenario with minimized condylar forces, tooth reaction forces could exceed 20,000 N despite lower magnitudes of muscle force. These bite forces at the teeth are consistent with bone indentations on Dorudon crania, reatract-and-shear hypotheses of Basilosaurus bite function, and seizure of prey by anterior teeth as proposed for other archaeocetes. The whale's bite forces match those estimated for pliosaurus when skull lengths are equalized, suggesting similar tradeoffs of bite function and hydrodynamics. Reaction forces in B. isis were lower than maxima estimated for large crocodylians and carnivorous dinosaurs. However, comparison of force estimates from FEA and regression data indicate that B. isis exerted the largest bite forces yet estimated for any mammal, and greater force than expected from its skull width. Cephalic feeding biomechanics of Basilosaurus isis are thus consistent with habitual predation.

PF-WFS Shell Inspection Update December 2016

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vigil, Anthony Eugene; Ledoux, Reina Rebecca; Gonzales, Antonio R.

Since the last project update in FY16:Q2, PF-WFS personnel have advanced in understanding of shell inspection on Coordinate Measuring Machines {CMM} and refined the PF-WFS process to the point it was decided to convert shell inspection from the Sheffield #1 gage to Lietz CM Ms. As a part of introspection on the quality of this process many sets of data have been reviewed and analyzed. This analysis included Sheffield to CMM comparisons, CMM inspection repeatability, fixturing differences, quality check development, probing approach changes. This update report will touch on these improvements that have built the confidence in this process tomore » mainstream it inspecting shells. In addition to the CMM programming advancements, the continuation in refinement of input and outputs for the CMM program has created an archiving scheme, input spline files, an output metafile, and inspection report package. This project will continue to mature. Part designs may require program modifications to accommodate "new to this process" part designs. Technology limitations tied to security and performance are requiring possible changes to computer configurations to support an automated process.« less

30 CFR 912.842 - Federal inspections.

Code of Federal Regulations, 2010 CFR

2010-07-01

... PROGRAMS FOR THE CONDUCT OF SURFACE MINING OPERATIONS WITHIN EACH STATE IDAHO § 912.842 Federal inspections... regarding inspections conducted pursuant to this section to the Office of the Idaho Attornery General upon...

Coordinated ionospheric and magnetospheric observations from the ISIS 2 satellite by the ISIS 2 experimenters. Volume 3: High-latitude charged particle, magnetic field and ionospheric plasma observations during northern summer

NASA Technical Reports Server (NTRS)

1980-01-01

A list of ISIS 2 experiments and a description of the satellite are presented. Instrumentation of the satellite included an auroral scanning photometer, a red line photometer, a swept frequency sounder, an ion mass spectrometer, and triaxial fluxgate magnetometer. Data format descriptions are provided. Included with the geophysical data set is a list of all passes.

Developing the Muon Facilities at ISIS

NASA Astrophysics Data System (ADS)

Hillier, A. D.; Aramini, M.; Baker, P. J.; Berlie, A.; Biswas, P. K.; Cottrell, S. P.; Ishida, K.; Loe, T.; Lord, J. S.; Pooley, D. E.; Pratt, F. L.; Rhodes, N. J.; da Silva Afonso, R. J.; Telling, M. T. F.; Yokoyama, K.

For the last 30 years, muon experiments at ISIS have been making a significant contribution to a number of scientific fields. However, as a community of researchers, we are always aiming to improve and extend the instruments' capabilities. In this paper, we will review key developments at the ISIS muon facility, the primary beamline upgrade and recent technique developments, before taking a forward look to new projects, such as: the upgrade for MuSR, e-learning, detector development and sample environment.

The process group approach to reliable distributed computing

NASA Technical Reports Server (NTRS)

Birman, Kenneth P.

1992-01-01

The difficulty of developing reliable distribution software is an impediment to applying distributed computing technology in many settings. Experience with the ISIS system suggests that a structured approach based on virtually synchronous process groups yields systems that are substantially easier to develop, exploit sophisticated forms of cooperative computation, and achieve high reliability. Six years of research on ISIS, describing the model, its implementation challenges, and the types of applications to which ISIS has been applied are reviewed.

On Developing Academic Literacy in the Mother Tongue for Epistemological Access: The Role of isiZulu as the LoLT in a South African University

ERIC Educational Resources Information Center

Mgqwashu, Emmanuel Mfanafuthi

2014-01-01

This paper reports on a study that examined the extent to which the development of academic literacy in isiZulu, an indigenous language spoken across all the nine provinces in South Africa, enhances opportunities for epistemological access. The focus is in relation to a pilot study of a Bachelor of Education Honours module that uses isiZulu as the…

[The struggle of early Christians against Isis medica: breaks and continuity in traditions in the context of health and healing].

PubMed

Moog, Ferdinand Peter

2009-01-01

The study of health and healing gods may offer significant examples of how certain ideas survive, with hardly any substantial loss, across periods of great change. It is no surprise that, following centuries of struggle by early Christians against the worship of pagan gods, some originally heathen ideas and elements of thinking should have been in due course, if with prudence, adapted to Christian needs and sensibilities. A most remarkable instance of such practice is to be found, somewhat surprisingly, in the life of the bishop St. Cyril of Alexandria. He opposed rigorously the cult of Isis, above all in Egypt, but nevertheless adapted features of Isis to his conception of the Blessed Virgin Mary as 'Theotokos'. In this manner Isis, the goddess-mother, with her child Horus became--in a certain measure--a type of the Blessed Virgin Mother of God, accompanied by the Infant Jesus. The legendary arson perpetrated at the start of the 6th century A.D. against a temple in Cologne wherein a healing deity was worshipped should, it is argued here for the first time, be understood in the context of conflict between early Christianity and the cult of Isis. There is good reason to believe that the aforementioned temple set on fire by Gallus, later Bishop of Clermont, was in fact the shrine of Isis in Cologne.

An evaluation of a bed instability index as an indicator of habitat quality in mountain streams of the northwestern United States

USGS Publications Warehouse

Kusnierz, Paul C.; Holbrook, Christopher; Feldman, David L.

2015-01-01

Managers of aquatic resources benefit from indices of habitat quality that are reproducible and easy to measure, demonstrate a link between habitat quality and biota health, and differ between human-impacted (i.e., managed) and reference (i.e., nonimpacted or minimally impacted) conditions. The instability index (ISI) is an easily measured index that describes the instability of a streambed by relating the tractive force of a stream at bankfull discharge to the median substrate size. Previous studies have linked ISI to biological condition but have been limited to comparisons of sites within a single stream or among a small number of streams. We tested ISI as an indicator of human impact to habitat and biota in mountain streams of the northwestern USA. Among 1428 sites in six northwestern states, ISI was correlated with other habitat measures (e.g., residual pool depth, percent fine sediment) and indices of biotic health (e.g., number of intolerant macroinvertebrate taxa, fine sediment biotic index) and differed between managed and reference sites across a range of stream types and ecoregions. While ISI could be useful in mountain streams throughout the world, this index may be of particular interest to aquatic resource managers in the northwestern USA where a large dataset, from which ISI can be calculated, exists.

Relative performance of three stream bed stability indices as indicators of stream health.

PubMed

Kusnierz, Paul C; Holbrook, Christopher M

2017-10-16

Bed stability is an important stream habitat attribute because it affects geomorphology and biotic communities. Natural resource managers desire indices of bed stability that can be used under a wide range of geomorphic conditions, are biologically meaningful, and are easily incorporated into sampling protocols. To eliminate potential bias due to presence of instream wood and increase precision of stability values, we modified a stream bed instability index (ISI) to include measurements of bankfull depth (d bf ) and median particle diameter (D 50 ) only in riffles and increased the pebble count to decrease variability (i.e., increase precision) in D 50 . The new riffle-based instability index (RISI) was compared to two established indices: ISI and the riffle stability index (RSI). RISI and ISI were strongly associated with each other but neither was closely associated with RSI. RISI and ISI were closely associated with both a diatom- and two macrovertebrate-based stream health indices, but RSI was only weakly associated with the macroinvertebrate indices. Unexpectedly, precision of D 50 did not differ between RISI and ISI. Results suggest that RISI is a viable alternative to both ISI and RSI for evaluating bed stability in multiple stream types. With few data requirements and a simple protocol, RISI may also better conform to riffle-based sampling methods used by some water quality practitioners.

Relative performance of three stream bed stability indices as indicators of stream health

USGS Publications Warehouse

Kusnierz, Paul C; Holbrook, Christopher

2017-01-01

Bed stability is an important stream habitat attribute because it affects geomorphology and biotic communities. Natural resource managers desire indices of bed stability that can be used under a wide range of geomorphic conditions, are biologically meaningful, and are easily incorporated into sampling protocols. To eliminate potential bias due to presence of instream wood and increase precision of stability values, we modified a stream bed instability index (ISI) to include measurements of bankfull depth (dbf) and median particle diameter (D50) only in riffles and increased the pebble count to decrease variability (i.e., increase precision) in D50.The new riffle-based instability index (RISI) was compared to two established indices: ISI and the riffle stability index (RSI). RISI and ISI were strongly associated with each other but neither was closely associated with RSI. RISI and ISI were closely associated with both a diatom- and two macrovertebrate-based stream health indices, but RSI was only weakly associated with the macroinvertebrate indices. Unexpectedly, precision of D50 did not differ between RISI and ISI. Results suggest that RISI is a viable alternative to both ISI and RSI for evaluating bed stability in multiple stream types. With few data requirements and a simple protocol, RISI may also better conform to riffle-based sampling methods used by some water quality practitioners.

Adaptive Detection and ISI Mitigation for Mobile Molecular Communication.

PubMed

Chang, Ge; Lin, Lin; Yan, Hao

2018-03-01

Current studies on modulation and detection schemes in molecular communication mainly focus on the scenarios with static transmitters and receivers. However, mobile molecular communication is needed in many envisioned applications, such as target tracking and drug delivery. Until now, investigations about mobile molecular communication have been limited. In this paper, a static transmitter and a mobile bacterium-based receiver performing random walk are considered. In this mobile scenario, the channel impulse response changes due to the dynamic change of the distance between the transmitter and the receiver. Detection schemes based on fixed distance fail in signal detection in such a scenario. Furthermore, the intersymbol interference (ISI) effect becomes more complex due to the dynamic character of the signal which makes the estimation and mitigation of the ISI even more difficult. In this paper, an adaptive ISI mitigation method and two adaptive detection schemes are proposed for this mobile scenario. In the proposed scheme, adaptive ISI mitigation, estimation of dynamic distance, and the corresponding impulse response reconstruction are performed in each symbol interval. Based on the dynamic channel impulse response in each interval, two adaptive detection schemes, concentration-based adaptive threshold detection and peak-time-based adaptive detection, are proposed for signal detection. Simulations demonstrate that the ISI effect is significantly reduced and the adaptive detection schemes are reliable and robust for mobile molecular communication.

On-line access to remote sensing data with the satellite-data information system (ISIS)

NASA Astrophysics Data System (ADS)

Strunz, G.; Lotz-Iwen, H.-J.

1994-08-01

The German Remote Sensing Data Center (DFD) is developing the satellite-data information system ISIS as central interface for users to access Earth observation data. ISIS has been designed to support international scientific research as well as operational applications by offering online database access via public networks, and is integrated in the international activities dedicated to catalogue and archive interoperability. A prototype of ISIS is already in use within the German Processing and Archiving Facility for ERS-1 for the storage and retrieval of digital SAR quicklook products and for the Radarmap of Germany. An operational status of the system is envisaged for the launch of ERS-2. The paper in hand describes the underlying concepts of ISIS and the recent state of realization. It explains the overall structure of the system and the functionality of each of its components. Emphasis is put on the description of the advisory system, the catalogue retrieval, and the online access and transfer of image data. Finally, the integration into a future global environmental data network is outlined.

ANNUAL RADIOACTIVE WASTE TANK INSPECTION PROGRAM 2010

DOE Office of Scientific and Technical Information (OSTI.GOV)

West, B.; Waltz, R.

Aqueous radioactive wastes from Savannah River Site (SRS) separations and vitrification processes are contained in large underground carbon steel tanks. Inspections made during 2010 to evaluate these vessels and other waste handling facilities along with evaluations based on data from previous inspections are the subject of this report. The 2010 inspection program revealed that the structural integrity and waste confinement capability of the Savannah River Site waste tanks were maintained. All inspections scheduled per SRR-LWE-2009-00138, HLW Tank Farm Inspection Plan for 2010, were completed. Ultrasonic measurements (UT) performed in 2010 met the requirements of C-ESG-00006, In-Service Inspection Program for Highmore » Level Waste Tanks, Rev. 3, and WSRC-TR-2002-00061, Rev.6. UT inspections were performed on Tanks 30, 31 and 32 and the findings are documented in SRNL-STI-2010-00533, Tank Inspection NDE Results for Fiscal Year 2010, Waste Tanks 30, 31 and 32. A total of 5824 photographs were made and 1087 visual and video inspections were performed during 2010. Ten new leaksites at Tank 5 were identified in 2010. The locations of these leaksites are documented in C-ESR-G-00003, SRS High Level Waste Tank Leaksite Information, Rev.5. Ten leaksites at Tank 5 were documented during tank wall/annulus cleaning activities. None of these new leaksites resulted in a release to the environment. The leaksites were documented during wall cleaning activities and the waste nodules associated with the leaksites were washed away. Previously documented leaksites were reactivated at Tank 12 during waste removal activities.« less

Formative evaluation of an Inspection Certificate Program (ICP) pilot in Toronto.

PubMed

Dwyer, J J; Komorowski, C; Ruf, F

1999-01-01

The inspection certificate program consists of food establishments voluntarily posting a certificate to inform patrons that inspection reports can be accessed from operators or the public health department. A three-month pilot program was evaluated for program improvement purposes. Only 65% of the selected operators were willing to participate, which suggests a challenge to fully implementing the program. Thirty-nine randomly selected restaurant operators participated. Most operators posted the certificate at the front entrance, and patrons indicated that reports were clear. Operators were supportive of the program. Some operators reported that the program was good for business and offered suggestions to improve it. A total of 583 requests for reports were made which suggests that the program empowered patrons to request reports, mostly from operators. Most patron evaluation forms came from a few operators that had no deficiencies, which limits generalizability.

19 CFR 12.11 - Requirements for entry and release.

Code of Federal Regulations, 2011 CFR

2011-04-01

... labels or Customs seals to the representative of the Animal and Plant Health Inspection Service, Plant... inspector of the Animal and Plant Health Inspection Service, Plant Protection and Quarantine Programs. (b... inspection or other treatment by a representative of the Animal and Plant Health Inspection Service, Plant...

78 FR 24666 - Updates to the List of Plant Inspection Stations

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-26

... plant material imported for plant breeding and research programs. The Plant Germplasm Inspection Station... DEPARTMENT OF AGRICULTURE Animal and Plant Health Inspection Service 7 CFR Part 319 [Docket No. APHIS-2012-0099] Updates to the List of Plant Inspection Stations AGENCY: Animal and Plant Health...

9 CFR 592.80 - Political activity.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Political activity. 592.80 Section 592.80 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION VOLUNTARY INSPECTION OF EGG PRODUCTS Performance of Services § 592.80 Political activity. All inspection program personnel are...

9 CFR 592.80 - Political activity.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false Political activity. 592.80 Section 592.80 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION VOLUNTARY INSPECTION OF EGG PRODUCTS Performance of Services § 592.80 Political activity. All inspection program personnel are...

9 CFR 592.80 - Political activity.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Political activity. 592.80 Section 592.80 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION VOLUNTARY INSPECTION OF EGG PRODUCTS Performance of Services § 592.80 Political activity. All inspection program personnel are...

9 CFR 592.70 - Identification.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 9 Animals and Animal Products 2 2014-01-01 2014-01-01 false Identification. 592.70 Section 592.70 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION VOLUNTARY INSPECTION OF EGG PRODUCTS Performance of Services § 592.70 Identification. All inspection program personnel and supervisors...

9 CFR 592.70 - Identification.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Identification. 592.70 Section 592.70 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION VOLUNTARY INSPECTION OF EGG PRODUCTS Performance of Services § 592.70 Identification. All inspection program personnel and supervisors...

9 CFR 592.80 - Political activity.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 9 Animals and Animal Products 2 2014-01-01 2014-01-01 false Political activity. 592.80 Section 592.80 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION VOLUNTARY INSPECTION OF EGG PRODUCTS Performance of Services § 592.80 Political activity. All inspection program personnel are...

9 CFR 592.70 - Identification.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Identification. 592.70 Section 592.70 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION VOLUNTARY INSPECTION OF EGG PRODUCTS Performance of Services § 592.70 Identification. All inspection program personnel and supervisors...

9 CFR 592.70 - Identification.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false Identification. 592.70 Section 592.70 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION VOLUNTARY INSPECTION OF EGG PRODUCTS Performance of Services § 592.70 Identification. All inspection program personnel and supervisors...

19 CFR 12.11 - Requirements for entry and release.

Code of Federal Regulations, 2010 CFR

2010-04-01

... inspector of the Animal and Plant Health Inspection Service, Plant Protection and Quarantine Programs. (b... inspection or other treatment by a representative of the Animal and Plant Health Inspection Service, Plant... labels or Customs seals to the representative of the Animal and Plant Health Inspection Service, Plant...

46 CFR 162.039-6 - Examinations, tests, and inspections.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 6 2010-10-01 2010-10-01 false Examinations, tests, and inspections. 162.039-6 Section..., Marine Type § 162.039-6 Examinations, tests, and inspections. (a) Full examinations, tests, and... such examinations, inspections, and tests as to satisfy himself that the quality assurance program of...

Quantifying the benefits of the Florida Transit Research Inspection Procurement Services (TRIPS) program : [research summary].

DOT National Transportation Integrated Search

2013-04-01

Established in 1995 as the Florida Vehicle : Procurement Program (FVPP), Florida Transit : Research Inspection Procurement Services (TRIPS) : is a vehicle sourcing and procurement system for : Floridas public transit agencies that integrates : ins...

Coordinated ionospheric and magnetospheric observations from the ISIS 2 satellite by the ISIS 2 experimenters. Volume 1: Optical auroral images and related direct measurements

NASA Technical Reports Server (NTRS)

Murphree, J. S.

1980-01-01

A representative set of data from ISIS 2 covering a range of operating modes and geophysical conditions is presented. The data show the typical values and range of ionospheric and magnetospheric characteristics, as viewed from 1400 km with the ISIS 2 instruments. The definition of each data set depends partly on geophysical parameters and partly on satellite operating mode. Preceding the data set is a description of the organizational parameters and a review of the objectives and general characteristics of the data set. The data are shown as a selection from 12 different data formats. Each data has a different selection of formats, but uniformity of a given format selection is preserved throughout each data set.

The ISIS Mission Concept: An Impactor for Surface and Interior Science

NASA Technical Reports Server (NTRS)

Chesley, Steven R.; Elliot, John O.; Abell, Paul A.; Asphaug, Erik; Bhaskaran, Shyam; Lam, Try; Lauretta, Dante S.

2013-01-01

The Impactor for Surface and Interior Science (ISIS) mission concept is a kinetic asteroid impactor mission to the target of NASA's OSIRIS-REx (Origins-Spectral Interpretation-Resource Identification-Security-Regolith Explorer) asteroid sample return mission. The ISIS mission concept calls for the ISIS spacecraft, an independent and autonomous smart impactor, to guide itself to a hyper-velocity impact with 1999 RQ36 while the OSIRIS-REx spacecraft observes the collision. Later the OSIRIS-REx spacecraft descends to reconnoiter the impact site and measure the momentum imparted to the asteroid through the impact before departing on its journey back to Earth. In this paper we discuss the planetary science, human exploration and impact mitigation drivers for mission, and we describe the current mission concept and flight system design.

THE COMMAND OF THE TREND: SOCIAL MEDIA AS A WEAPON IN THE INFORMATION AGE

DTIC Science & Technology

2017-06-01

and a bot network) based on the analysis within this case study . Table 3. ISIS Case Study Analysis Propaganda Narratives 1. ISIS is strong...get started with an interview and included me in a cyber think-tank for the study of ISIS activity on social media. Additionally, I am still... study demonstrates how social media is a tool for modern warfare in the information age. The report builds on analysis of three distinct topics

Evaluation Of Back Shape Using The ISIS Scanner

NASA Astrophysics Data System (ADS)

Turner-Smith, Alan R.; Thomas, David C.

1989-04-01

The Integrated Shape Investigation System (ISIS) is a structured light scanner and shape analysis system, developed as a safe alternative to follow-up radiographs for the clinical assessment of deformities of the human back. The system is described and results presented of several clinic studies. These show a significant correlation between ISIS measures and conventional radiographic measures of spinal curvature, such as the Cobb angle. The development of a predictor for deterioration in adolescent idiopathic scoliosis, based on surface shape weasures, is discussed.

Ideology Has No Borders: Why We Need a Containment-Plus Strategy for the Islamic State

DTIC Science & Technology

2015-04-01

Deft Command of Varied Media 50 Brooking, The U.S. Government Should Pay Anonymous in Bitcoin to Fight ISIS 51 Francis, Why Don Draper Would Be...Government Should Pay Anonymous in Bitcoin to Fight ISIS. Foreign Policy, 3 March 2015. http://foreignpolicy.com/2015/03/03/the-u-s-government-should...pay-anonymous-in- bitcoin -to-fight-isis/ (accessed 7 March 2015). Churchill, Winston. The Sinews of Peace (Iron Curtain Speech). Westminster College

49 CFR 109.3 - Inspections and Investigations.

Code of Federal Regulations, 2014 CFR

2014-10-01

....3 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HAZARDOUS MATERIALS AND OIL TRANSPORTATION HAZARDOUS MATERIALS PROGRAM PROCEDURES Inspections and Investigations § 109.3 Inspections and Investigations. (a...

FAA National Aviation Safety Inspection Program. Annual Report FY90

DOT National Transportation Integrated Search

1991-06-01

This report was undertaken to document, analyze, and place : into national perspective the findings from the 1990 National : Aviation Safety Inspection Program (NASIP). This report is the : fifth in a series of annual reports covering the results of ...

7 CFR 371.5 - Marketing and Regulatory Programs Business Services.

Code of Federal Regulations, 2014 CFR

2014-01-01

..., programs, and activities. Providing human resource, certain financial, and management services for AMS... PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ORGANIZATION, FUNCTIONS, AND DELEGATIONS OF... management services. (3) Conducting administrative reviews and inspections in APHIS to assess the...

7 CFR 371.5 - Marketing and Regulatory Programs Business Services.

Code of Federal Regulations, 2013 CFR

2013-01-01

..., programs, and activities. Providing human resource, certain financial, and management services for AMS... PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ORGANIZATION, FUNCTIONS, AND DELEGATIONS OF... management services. (3) Conducting administrative reviews and inspections in APHIS to assess the...

7 CFR 371.5 - Marketing and Regulatory Programs Business Services.

Code of Federal Regulations, 2012 CFR

2012-01-01

..., programs, and activities. Providing human resource, certain financial, and management services for AMS... PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ORGANIZATION, FUNCTIONS, AND DELEGATIONS OF... management services. (3) Conducting administrative reviews and inspections in APHIS to assess the...

NDE detectability of fatigue-type cracks in high-strength alloys: NDI reliability assessments

NASA Technical Reports Server (NTRS)

Christner, Brent K.; Long, Donald L.; Rummel, Ward D.

1988-01-01

This program was conducted to generate quantitative flaw detection capability data for the nondestructive evaluation (NDE) techniques typically practiced by aerospace contractors. Inconel 718 and Haynes 188 alloy test specimens containing fatigue flaws with a wide distribution of sizes were used to assess the flaw detection capabilities at a number of contractor and government facilities. During this program 85 inspection sequences were completed presenting a total of 20,994 fatigue cracks to 53 different inspectors. The inspection sequences completed included 78 liquid penetrant, 4 eddy current, and 3 ultrasonic evaluations. The results of the assessment inspections are presented and discussed. In generating the flaw detection capability data base, procedures for data collection, data analysis, and specimen care and maintenance were developed, demonstrated, and validated. The data collection procedures and methods that evolved during this program for the measurement of flaw detection capabilities and the effects of inspection variables on performance are discussed. The Inconel 718 and Haynes 188 test specimens that were used in conducting this program and the NDE assessment procedures that were demonstrated, provide NASA with the capability to accurately assess the flaw detection capabilities of specific inspection procedures being applied or proposed for use on current and future fracture control hardware program.

9 CFR 327.6 - Products for importation; program inspection, time and place; application for approval of...

Code of Federal Regulations, 2010 CFR

2010-01-01

... Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY... into the United States. (2) Every lot of product shall routinely be given visual inspection by a... Food Safety and Inspection Service. The listing will categorize the kind or kinds of product 2 which...

Probabilistic inspection strategies for minimizing service failures

NASA Technical Reports Server (NTRS)

Brot, Abraham

1994-01-01

The INSIM computer program is described which simulates the 'limited fatigue life' environment in which aircraft structures generally operate. The use of INSIM to develop inspection strategies which aim to minimize service failures is demonstrated. Damage-tolerance methodology, inspection thresholds and customized inspections are simulated using the probability of failure as the driving parameter.

9 CFR 592.240 - Report of violations.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Report of violations. 592.240 Section 592.240 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION VOLUNTARY INSPECTION OF EGG PRODUCTS Denial of Service § 592.240 Report of violations. Each inspection program employee shall...

9 CFR 592.240 - Report of violations.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Report of violations. 592.240 Section 592.240 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION VOLUNTARY INSPECTION OF EGG PRODUCTS Denial of Service § 592.240 Report of violations. Each inspection program employee shall...

9 CFR 592.240 - Report of violations.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 9 Animals and Animal Products 2 2014-01-01 2014-01-01 false Report of violations. 592.240 Section 592.240 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION VOLUNTARY INSPECTION OF EGG PRODUCTS Denial of Service § 592.240 Report of violations. Each inspection program employee shall...

9 CFR 592.240 - Report of violations.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false Report of violations. 592.240 Section 592.240 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION VOLUNTARY INSPECTION OF EGG PRODUCTS Denial of Service § 592.240 Report of violations. Each inspection program employee shall...

Visual inspection reliability of transport aircraft

NASA Astrophysics Data System (ADS)

Spencer, Floyd W.

1996-11-01

The Federal Aviation Administration Technical Center has sponsored a visual inspection reliability program at its airworthiness assurance nondestructive inspection validation center (AANC). We report on the results of the benchmark phase of that program in which 12 inspectors were observed in two days of inspections on a Boeing 737 aircraft. All of the inspectors were currently employed with major airlines and all had experience inspecting the Boeing 737 aircraft. Each inspector spent 2 days at the AANC facility where they inspected to the same ten job cards. Each inspector was videotaped and all nonroutine repair actions were recorded for each inspector. Background information on each of the inspectors, including vision test results, was also gathered. The inspection results were correlated with the background variables. Aviation experience and a test time reflecting visual acuity were significantly correlated with performance factors. An analysis of the video tapes was performed to separate decision errors from search errors. Probability of detection curves were fit to the results of inspecting for cracks from beneath rivet heads in a task using prepared samples with known cracks.

78 FR 6065 - Submission for OMB Review; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-29

... a currently valid OMB control number. Animal and Plant Health Inspection Service Title: Tuberculosis... Health Inspection Service (APHIS) participates in the Cooperative State-Federal Bovine Tuberculosis Eradication Program, which is a national program to eliminate bovine tuberculosis from the United States. This...

30 CFR 840.15 - Public participation.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Mineral Resources OFFICE OF SURFACE MINING RECLAMATION AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR PERMANENT PROGRAM INSPECTION AND ENFORCEMENT PROCEDURES STATE REGULATORY AUTHORITY: INSPECTION AND... enforcement of the State program consistent with that provided by 30 CFR parts 842, 843 and 845 and 43 CFR...

30 CFR 840.15 - Public participation.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Mineral Resources OFFICE OF SURFACE MINING RECLAMATION AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR PERMANENT PROGRAM INSPECTION AND ENFORCEMENT PROCEDURES STATE REGULATORY AUTHORITY: INSPECTION AND... enforcement of the State program consistent with that provided by 30 CFR parts 842, 843 and 845 and 43 CFR...

Perineal swelling, intermenstrual cycle, and female sexual behavior in bonobos (Pan paniscus).

PubMed

Paoli, T; Palagi, E; Tacconi, G; Tarli, S Borgognini

2006-04-01

Many reports have claimed that the duration of the swelling cycle in female bonobos (Pan paniscus) is longer than that of chimpanzees, and that the bonobo maximum swelling phase is markedly prolonged. Field data on intermenstrual intervals (IMIs) in female bonobos are limited and restricted to interswelling intervals (ISIs), which are assumed to reflect the IMI, though a direct comparison between the duration of ISIs and IMIs is still lacking. Reports on bonobo sexual activity as a function of the swelling phase are often contradictory. Moreover, the function of female homosexual interactions (genito-genital (GG) rubbing) is still debated. This study examines the reliability of the ISI as an approximation of the IMI, and the attractivity of female sexual swellings for other individuals. An analysis of 51 ISI-IMI pairs showed that ISIs are a fair representation of the reproductive cycle. The cycle length was 35.6+/-1.1 SE days relying on the ISI, whereas it was 35.0+/-1.1 SE days considering the IMI. This result is similar to the cycle length reported for chimpanzees. Female homosexual interactions and copulatory rates were higher during maximum tumescence, suggesting that the sexual swelling may be attractive for both males and other females. Furthermore, the GG-rubbing was performed free of a hierarchical postural imposition, and was not correlated with affinitive interactions. We suggest that GG-rubbing, which is generally the most frequent female sexual interaction, is a tool for social assessments among females. Copyright (c) 2006 Wiley-Liss, Inc.

Diarrheal disease on cruise ships, 1990-2000: the impact of environmental health programs.

PubMed

Cramer, Elaine H; Gu, David X; Durbin, Randy E

2003-04-01

In 1975, the then-Center for Disease Control (CDC) established the Vessel Sanitation Program (VSP) to minimize the risk for diarrheal disease among passengers and crew aboard ships by assisting the cruise ship industry in developing and implementing comprehensive environmental health programs. To evaluate the relationship between cruise ship sanitation scores and diarrheal disease incidence and outbreaks among cruise ship passengers. Retrospective cohort study of ship inspection and diarrheal disease data from 1990 through 2000 from the National Center for Environmental Health, CDC database, for cruise ships entering the United States. Yearly trends in number of ships inspected, number of inspections conducted, inspection scores, and risks of failing inspections; rates of diarrheal disease among passengers, by inspection year, cruise duration, incidence of outbreaks, and passing- or failing-score status of the associated ship. From 1990 through 2000, inspection scores gradually increased from a median of 89 in 1990 to 93 in 2000 (p<0.001), with an associated statistically significant 21% increase in likelihood of passing. The total baseline level of diarrhea among passengers was 2.0 cases per cruise (13243/6485), or 23.6 cases per 100,000 passenger-days (13243/56129096). The latter rate declined significantly from 29.2 in 1990 to 16.3 in 2000 (p<0.0001). Diarrheal disease incidence rates among passengers sailing on ships that passed environmental inspections were significantly lower than rates among passengers sailing on ships that failed inspections (21.7 vs 30.1; RR = 1.39; 95% CI: 1.31-1.47). Diarrheal disease outbreak-related illnesses decreased from 4.2 to 3.5 per 100000 passenger-days from 1990-1995 to 1996-2000. Environmental sanitation inspections conducted among ships sailing into the United States appear to continue to decrease diarrheal disease rates and outbreaks among passengers.

A Four-Session Sleep Intervention Program Improves Sleep for Older Adult Day Health Care Participants: Results of a Randomized Controlled Trial

PubMed Central

Song, Yeonsu; Hughes, Jaime; Jouldjian, Stella; Dzierzewski, Joseph M.; Fung, Constance H; Rodriguez Tapia, Juan Carlos; Mitchell, Michael N.; Alessi, Cathy A

2017-01-01

Abstract Study Objective To test the effectiveness of a 4-week behavioral Sleep Intervention Program (SIP: sleep compression, modified stimulus control, and sleep hygiene) compared to a 4-week information-only control (IC) among older adults attending a VA Adult Day Health Care (ADHC) program in a double-blind, randomized, clinical trial. Methods Forty-two individuals (mean age: 77 years, 93% male) enrolled in a VA ADHC program were randomized to receive SIP or IC. All completed in-person sleep and health assessments at baseline, post-treatment and 4-months follow-up that included 3 days/nights of wrist actigraphy, the Pittsburgh Sleep Quality Index (PSQI), and the Insomnia Severity Index (ISI). Mixed repeated measures analysis was used to compare sleep outcomes at post-treatment and 4-months follow-up, with baseline values as covariates. Results SIP participants (n = 21) showed significant improvement on actigraphy sleep efficiency (p = .007), number of nighttime awakenings (p = .016), and minutes awake at night (p = .001) at post-treatment, compared to IC participants (n = 21). Benefits were slightly attenuated but remained significant at 4-month follow-up (all p’s < .05). There were no differences in total sleep time between groups. There was significant improvement on PSQI factor 3 (daily disturbances) at 4-month follow-up (p = .016), but no differences were observed between SIP and IC on other PSQI components or ISI scores at post-treatment or 4-month follow-up. Conclusions A short behavioral sleep intervention may have important benefits in improving objectively measured sleep in older adults participating in ADHC. Future studies are needed to study implementation of this intervention into routine clinical care within ADHC. PMID:28482053

National Dam Inspection Program. Lake Jean Dam. (NDI I.D. Number PA-00570 PennDER I.D. Number 40-16) Susquehanna River Basin, Branch of Kitchen Creek, Luzerne County, Pennsylvania. Phase I Inspection Report,

DTIC Science & Technology

1980-07-01

ANALYSES APPENDIX E - FIGURES APPENDIX F - GEOLOGY 1 v~i I LI PHASE I INSPECTION REPORT NATIONAL DAM INSPECTION PROGRAM LAKE JEAN DAM NDI# PA-00570...Red Rock, Pennsylvania, U.S.G.S. 7.5 minute topographic quadrangle (see Figure 1, Appendix E ). The coordinates of the dam are N41* 21.1’ and W76 0...3.1. e ). e . Ownership. Commonwealth of Pennsylvania Office of Resources Management Department of Environmental Resources P.O. Box 1467 Harrisburg

National Dam Inspection Program. Indian Lake Dam (NDI I.D. PA-0057 DER I.D. 058-038) Susquehanna River Basin, White Creek, Susquehanna County, Pennsylvania. Phase I Inspection Report,

DTIC Science & Technology

1981-03-19

c&A.j cDAN MAYI 81981 (I D. PA-005𔄁 DER I.D. V58-038.) / PHASE I INSPECTION REPORT NATIONAL DAM INSPECTION PROGRAM cf /9 . I! PRFPAR’"b FOR...square miles( l ) b. Discharge at Dam Site ( cfs ) Maximum known flood at dam site Unknown Outlet conduit at maximum pool Unknown Gated spillway capacity...indicates that the spillway was sized to pass a discharge of 740 cfs with the water level six inches below the top of the darn and 925 cfs with the water

Performance assessment of small-package-class nonintrusive inspection systems

NASA Astrophysics Data System (ADS)

Spradling, Michael L.; Hyatt, Roger

1997-02-01

The DoD Counterdrug Technology Development Program has addressed the development and demonstration of technology to enhance nonintrusive inspection of small packages such as passenger baggage, commercially delivered parcels, and breakbulk cargo items. Within the past year they have supported several small package-class nonintrusive inspection system performance assessment activities. All performance assessment programs involved the use of a red/blue team concept and were conducted in accordance with approved assessment protocols. This paper presents a discussion related to the systematic performance assessment of small package-class nonintrusive inspection technologies, including transmission, backscatter and computed tomography x-ray imaging, and protocol-related considerations for the assessment of these systems.

FAA center for aviation systems reliability: an overview

NASA Astrophysics Data System (ADS)

Brasche, Lisa J. H.

1996-11-01

The FAA Center for Aviation Systems Reliability has as its objectives: to develop quantitative nondestructive evaluation (NDE) methods for aircraft structures and materials, including prototype instrumentation, software, techniques and procedures; and to develop and maintain comprehensive education and training programs specific to the inspection of aviation structures. The program, which includes contributions from Iowa State University, Northwestern University, Wayne State University, Tuskegee University, AlliedSignal Propulsion Engines, General Electric Aircraft Engines and Pratt and Whitney, has been in existence since 1990. Efforts under way include: development of inspection for adhesively bonded structures; detection of corrosion; development of advanced NDE concepts that form the basis for an inspection simulator; improvements of titanium inspection as part of the Engine Titanium Consortium; development of education and training program. An overview of the efforts underway will be provided with focus on those technologies closest to technology transfer.

Risk/benefit assessment of delayed action concept for rail inspection

DOT National Transportation Integrated Search

1999-02-01

A Monte Carlo simulation of certain aspects of rail inspection is presented. The simulation is used to investigate alternative practices in railroad rail inspection programs. Results are presented to compare the present practice of immediately repair...

Ageing airplane repair assessment program for Airbus A300

NASA Technical Reports Server (NTRS)

Gaillardon, J. M.; Schmidt, HANS-J.; Brandecker, B.

1992-01-01

This paper describes the current status of the repair categorization activities and includes all details about the methodologies developed for determination of the inspection program for the skin on pressurized fuselages. For inspection threshold determination two methods are defined based on fatigue life approach, a simplified and detailed method. The detailed method considers 15 different parameters to assess the influences of material, geometry, size location, aircraft usage, and workmanship on the fatigue life of the repair and the original structure. For definition of the inspection intervals a general method is developed which applies to all concerned repairs. For this the initial flaw concept is used by considering 6 parameters and the detectable flaw sizes depending on proposed nondestructive inspection methods. An alternative method is provided for small repairs allowing visual inspection with shorter intervals.

Pilot factors guidelines for the operational inspection of navigation systems

NASA Technical Reports Server (NTRS)

Sadler, J. F.; Boucek, G. P.

1988-01-01

A computerized human engineered inspection technique is developed for use by FAA inspectors in evaluating the pilot factors aspects of aircraft navigation systems. The short title for this project is Nav Handbook. A menu-driven checklist, computer program and data base (Human Factors Design Criteria) were developed and merged to form a self-contained, portable, human factors inspection checklist tool for use in a laboratory or field setting. The automated checklist is tailored for general aviation navigation systems and can be expanded for use with other aircraft systems, transports or military aircraft. The Nav Handbook inspection concept was demonstrated using a lap-top computer and an Omega/VLF CDU. The program generates standardized inspection reports. Automated checklists for LORAN/C and R NAV were also developed. A Nav Handbook User's Guide is included.

The effects of interstimulus interval on event-related indices of attention: an auditory selective attention test of perceptual load theory.

PubMed

Gomes, Hilary; Barrett, Sophia; Duff, Martin; Barnhardt, Jack; Ritter, Walter

2008-03-01

We examined the impact of perceptual load by manipulating interstimulus interval (ISI) in two auditory selective attention studies that varied in the difficulty of the target discrimination. In the paradigm, channels were separated by frequency and target/deviant tones were softer in intensity. Three ISI conditions were presented: fast (300ms), medium (600ms) and slow (900ms). Behavioral (accuracy and RT) and electrophysiological measures (Nd, P3b) were observed. In both studies, participants evidenced poorer accuracy during the fast ISI condition than the slow suggesting that ISI impacted task difficulty. However, none of the three measures of processing examined, Nd amplitude, P3b amplitude elicited by unattended deviant stimuli, or false alarms to unattended deviants, were impacted by ISI in the manner predicted by perceptual load theory. The prediction based on perceptual load theory, that there would be more processing of irrelevant stimuli under conditions of low as compared to high perceptual load, was not supported in these auditory studies. Task difficulty/perceptual load impacts the processing of irrelevant stimuli in the auditory modality differently than predicted by perceptual load theory, and perhaps differently than in the visual modality.

Online extremism and the communities that sustain it: Detecting the ISIS supporting community on Twitter

PubMed Central

Joseph, Kenneth; Carley, Kathleen M.

2017-01-01

The Islamic State of Iraq and ash-Sham (ISIS) continues to use social media as an essential element of its campaign to motivate support. On Twitter, ISIS’ unique ability to leverage unaffiliated sympathizers that simply retweet propaganda has been identified as a primary mechanism in their success in motivating both recruitment and “lone wolf” attacks. The present work explores a large community of Twitter users whose activity supports ISIS propaganda diffusion in varying degrees. Within this ISIS supporting community, we observe a diverse range of actor types, including fighters, propagandists, recruiters, religious scholars, and unaffiliated sympathizers. The interaction between these users offers unique insight into the people and narratives critical to ISIS’ sustainment. In their entirety, we refer to this diverse set of users as an online extremist community or OEC. We present Iterative Vertex Clustering and Classification (IVCC), a scalable analytic approach for OEC detection in annotated heterogeneous networks, and provide an illustrative case study of an online community of over 22,000 Twitter users whose online behavior directly advocates support for ISIS or contibutes to the group’s propaganda dissemination through retweets. PMID:29194446

Retention interval affects visual short-term memory encoding.

PubMed

Bankó, Eva M; Vidnyánszky, Zoltán

2010-03-01

Humans can efficiently store fine-detailed facial emotional information in visual short-term memory for several seconds. However, an unresolved question is whether the same neural mechanisms underlie high-fidelity short-term memory for emotional expressions at different retention intervals. Here we show that retention interval affects the neural processes of short-term memory encoding using a delayed facial emotion discrimination task. The early sensory P100 component of the event-related potentials (ERP) was larger in the 1-s interstimulus interval (ISI) condition than in the 6-s ISI condition, whereas the face-specific N170 component was larger in the longer ISI condition. Furthermore, the memory-related late P3b component of the ERP responses was also modulated by retention interval: it was reduced in the 1-s ISI as compared with the 6-s condition. The present findings cannot be explained based on differences in sensory processing demands or overall task difficulty because there was no difference in the stimulus information and subjects' performance between the two different ISI conditions. These results reveal that encoding processes underlying high-precision short-term memory for facial emotional expressions are modulated depending on whether information has to be stored for one or for several seconds.

78 FR 35056 - Effectiveness of the Reactor Oversight Process Baseline Inspection Program

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-11

... NUCLEAR REGULATORY COMMISSION [NRC-2013-0125] Effectiveness of the Reactor Oversight Process... the effectiveness of the reactor oversight process (ROP) baseline inspection program with members of... Nuclear Reactor Regulations, U.S. Nuclear Regulatory Commission, Washington, DC 20555-0001; telephone: 301...

Introduction to HACCP.

USDA-ARS?s Scientific Manuscript database

The Hazard Analysis and Critical Control Point (HACCP) food safety inspection program is utilized by both USDA Food Safety Inspection Service (FSIS) and FDA for many of the products they regulate. This science-based program was implemented by the USDA FSIS to enhance the food safety of meat and pou...

Notification: Effectiveness of EPA's Oversight of State Vehicle Inspection and Maintenance Programs in Achieving Emission Reductions

EPA Pesticide Factsheets

Project #OPE-FYI7-0018, May 5, 2017. The EPA OIG plans to begin preliminary research to determine whether EPA oversight has ensured that vehicle inspection and maintenance programs are effective and efficient in reducing vehicle emissions.

40 CFR 52.2348 - National Highway Systems Designation Act Motor Vehicle Inspection and Maintenance (I/M) Programs.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 4 2011-07-01 2011-07-01 false National Highway Systems Designation Act Motor Vehicle Inspection and Maintenance (I/M) Programs. 52.2348 Section 52.2348 Protection of... and Maintenance (I/M) Programs. (a) On March 15, 1996 the Governor of Utah submitted a revised I/M...

40 CFR 52.2348 - National Highway Systems Designation Act Motor Vehicle Inspection and Maintenance (I/M) Programs.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 4 2010-07-01 2010-07-01 false National Highway Systems Designation Act Motor Vehicle Inspection and Maintenance (I/M) Programs. 52.2348 Section 52.2348 Protection of... and Maintenance (I/M) Programs. (a) On March 15, 1996 the Governor of Utah submitted a revised I/M...

23 CFR 661.55 - How are BIA and Tribal owned IRR bridges inspected?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 23 Highways 1 2011-04-01 2011-04-01 false How are BIA and Tribal owned IRR bridges inspected? 661... AND TRAFFIC OPERATIONS INDIAN RESERVATION ROAD BRIDGE PROGRAM § 661.55 How are BIA and Tribal owned IRR bridges inspected? BIA and Tribally owned IRR bridges are inspected in accordance with 25 CFR part...

9 CFR 592.410 - Where to file an appeal.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Where to file an appeal. 592.410 Section 592.410 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION VOLUNTARY INSPECTION OF EGG PRODUCTS Appeals § 592.410 Where to file an appeal. (a) Appeal of inspection program personnel...

9 CFR 592.410 - Where to file an appeal.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Where to file an appeal. 592.410 Section 592.410 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION VOLUNTARY INSPECTION OF EGG PRODUCTS Appeals § 592.410 Where to file an appeal. (a) Appeal of inspection program personnel...

9 CFR 592.410 - Where to file an appeal.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 9 Animals and Animal Products 2 2014-01-01 2014-01-01 false Where to file an appeal. 592.410 Section 592.410 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION VOLUNTARY INSPECTION OF EGG PRODUCTS Appeals § 592.410 Where to file an appeal. (a) Appeal of inspection program personnel...

9 CFR 592.410 - Where to file an appeal.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false Where to file an appeal. 592.410 Section 592.410 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION VOLUNTARY INSPECTION OF EGG PRODUCTS Appeals § 592.410 Where to file an appeal. (a) Appeal of inspection program personnel...

29 CFR 1956.64 - Location of plan for inspection and copying.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 9 2010-07-01 2010-07-01 false Location of plan for inspection and copying. 1956.64... PLANS New Jersey § 1956.64 Location of plan for inspection and copying. A copy of the plan may be inspected and copied during normal business hours at the following locations: Office of State Programs, U.S...

23 CFR 661.55 - How are BIA and Tribal owned IRR bridges inspected?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 23 Highways 1 2010-04-01 2010-04-01 false How are BIA and Tribal owned IRR bridges inspected? 661... AND TRAFFIC OPERATIONS INDIAN RESERVATION ROAD BRIDGE PROGRAM § 661.55 How are BIA and Tribal owned IRR bridges inspected? BIA and Tribally owned IRR bridges are inspected in accordance with 25 CFR part...

Preliminary ISIS users manual

NASA Technical Reports Server (NTRS)

Grantham, C.

1979-01-01

The Interactive Software Invocation (ISIS), an interactive data management system, was developed to act as a buffer between the user and host computer system. The user is provided by ISIS with a powerful system for developing software or systems in the interactive environment. The user is protected from the idiosyncracies of the host computer system by providing such a complete range of capabilities that the user should have no need for direct access to the host computer. These capabilities are divided into four areas: desk top calculator, data editor, file manager, and tool invoker.

A New Inversion Routine to Produce Vertical Electron-Density Profiles from Ionospheric Topside-Sounder Data

NASA Technical Reports Server (NTRS)

Wang, Yongli; Benson, Robert F.

2011-01-01

Two software applications have been produced specifically for the analysis of some million digital topside ionograms produced by a recent analog-to-digital conversion effort of selected analog telemetry tapes from the Alouette-2, ISIS-1 and ISIS-2 satellites. One, TOPIST (TOPside Ionogram Scalar with True-height algorithm) from the University of Massachusetts Lowell, is designed for the automatic identification of the topside-ionogram ionospheric-reflection traces and their inversion into vertical electron-density profiles Ne(h). TOPIST also has the capability of manual intervention. The other application, from the Goddard Space Flight Center based on the FORTRAN code of John E. Jackson from the 1960s, is designed as an IDL-based interactive program for the scaling of selected digital topside-sounder ionograms. The Jackson code has also been modified, with some effort, so as to run on modern computers. This modification was motivated by the need to scale selected ionograms from the millions of Alouette/ISIS topside-sounder ionograms that only exist on 35-mm film. During this modification, it became evident that it would be more efficient to design a new code, based on the capabilities of present-day computers, than to continue to modify the old code. Such a new code has been produced and here we will describe its capabilities and compare Ne(h) profiles produced from it with those produced by the Jackson code. The concept of the new code is to assume an initial Ne(h) and derive a final Ne(h) through an iteration process that makes the resulting apparent-height profile fir the scaled values within a certain error range. The new code can be used on the X-, O-, and Z-mode traces. It does not assume any predefined profile shape between two contiguous points, like the exponential rule used in Jackson s program. Instead, Monotone Piecewise Cubic Interpolation is applied in the global profile to keep the monotone nature of the profile, which also ensures better smoothness in the final profile than in Jackson s program. The new code uses the complete refractive index expression for a cold collisionless plasma and can accommodate the IGRF, T96, and other geomagnetic field models.

Instrumentation and data analysis design for evaluating mechanic performance in decentralized I/M programs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ashby, H.A.; Carlson, T.R.; Husson, L.

1986-01-01

Significant reductions in motor vehicle emissions are possible through the implementation of inspection and maintenance (I/M) programs. However, the potential benefits of I/M are obviously not achieved when specific inspection requirements are ignored or improperly performed. In addition, I/M benefits may be substantially reduced when improper repair procedures are used on vehicles which fail the test. In order for the ''theoretical'' benefits of I/M to be achieved, certain program design and enforcement procedures are necessary. The use of instrumentation and data analysis methods capable of identifying individuals who are improperly performing inspections and repairs is critical.

A longitudinal study of youth assets, neighborhood conditions, and youth sexual behaviors.

PubMed

Oman, Roy F; Vesely, Sara K; Aspy, Cheryl B; Tolma, Eleni L; Gavin, Lorrie; Bensyl, Diana M; Mueller, Trisha; Fluhr, Janene D

2013-06-01

To prospectively determine whether individual, family, and community assets help youth to delay initiation of sexual intercourse (ISI); and for youth who do initiate intercourse, to use birth control and avoid pregnancy. The potential influence of neighborhood conditions was also investigated. The Youth Asset Study was a 4-year longitudinal study involving 1,089 youth (mean age = 14.2 years, standard deviation = 1.6; 53% female; 40% white, 28% Hispanic, 23% African American, 9% other race) and their parents. Participants were living in randomly selected census tracts. We accomplished recruitment via door-to-door canvassing. We interviewed one youth and one parent from each household annually. We assessed 17 youth assets (e.g., responsible choices, family communication) believed to influence behavior at multiple levels via in-person interviews methodology. Trained raters who conducted annual windshield tours assessed neighborhood conditions. Cox proportional hazard or marginal logistic regression modeling indicated that 11 assets (e.g., family communication, school connectedness) were significantly associated with reduced risk for ISI; seven assets (e.g., educational aspirations for the future, responsible choices) were significantly associated with increased use of birth control at last sex; and 10 assets (e.g., family communication, school connectedness) were significantly associated with reduced risk for pregnancy. Total asset score was significantly associated with all three outcomes. Positive neighborhood conditions were significantly associated with increased birth control use, but not with ISI or pregnancy. Programming to strengthen youth assets may be a promising strategy for reducing youth sexual risk behaviors. Copyright © 2013 Society for Adolescent Health and Medicine. All rights reserved.

Design and Flight Testing of an Inflatable Sunshield for the NGST

NASA Technical Reports Server (NTRS)

Adams, Michael L.; Culver, Harry L.; Kaufman, David M.; Pacini, Linda K.; Sturm, James; Lienard, Sebastien

2000-01-01

The Next Generation Space Telescope (NGST) mission is scheduled to launch in 2007 and be stationed at L2 for a mission life of ten years. The large aperture mirror and optical detectors aboard NGST require shielding from the constant solar energy seen at this orbit. The government reference NGST design, called the Yardstick, baselined a sunshield using an inflation deployment system. During the formulation phase, NGST is spending approximately 25% of the overall budget to foster the development of new technology. The goal is to develop and demonstrate enabling or enhancing technology and provide innovative solutions for the design of the NGST observatory. Inflatable technology falls in the category of enhancing technology due to its advantages in weight, stowed volume and cost. The Inflatable Sunshield in Space (ISIS) flight experiment will provide a realistic space flight demonstration of an inflatable sunshield. The supporting technology development program will provide an information base for the design, manufacture, assembly and testing of large thin membranes and inflatable structural elements for space structures. The ISIS experiment will demonstrate the feasibility of using inflatable technology to passively cool optical systems for NGST and provide correlation between analytical predictions and on orbit results. The experiment will be performed on a Hitchhiker/Space Shuttle mission in late 2001. The ISIS mission is an effort to address several major technical challenges of the NGST inflatable sunshield, namely controlled inflation deployment, plenarity and separation of large stretched membranes, space rigidization of inflatable booms, and dynamic modeling and simulation. This paper will describe the design of the flight experiment and the testing to be performed on-orbit.

42 CFR 456.607 - Notification before inspection.

Code of Federal Regulations, 2012 CFR

2012-10-01

....607 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS UTILIZATION CONTROL Inspections of Care in Intermediate Care Facilities and Institutions for Mental Diseases § 456.607 Notification before inspection. No facility may be...

42 CFR 456.606 - Frequency of inspections.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS UTILIZATION CONTROL Inspections of Care in Intermediate Care Facilities and Institutions for Mental Diseases § 456.606 Frequency of inspections. The team and the agency...

42 CFR 456.606 - Frequency of inspections.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS UTILIZATION CONTROL Inspections of Care in Intermediate Care Facilities and Institutions for Mental Diseases § 456.606 Frequency of inspections. The team and the agency...

42 CFR 456.607 - Notification before inspection.

Code of Federal Regulations, 2011 CFR

2011-10-01

....607 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS UTILIZATION CONTROL Inspections of Care in Intermediate Care Facilities and Institutions for Mental Diseases § 456.607 Notification before inspection. No facility may be...

42 CFR 456.606 - Frequency of inspections.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS UTILIZATION CONTROL Inspections of Care in Intermediate Care Facilities and Institutions for Mental Diseases § 456.606 Frequency of inspections. The team and the agency...

42 CFR 456.607 - Notification before inspection.

Code of Federal Regulations, 2014 CFR

2014-10-01

....607 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS UTILIZATION CONTROL Inspections of Care in Intermediate Care Facilities and Institutions for Mental Diseases § 456.607 Notification before inspection. No facility may be...

42 CFR 456.606 - Frequency of inspections.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS UTILIZATION CONTROL Inspections of Care in Intermediate Care Facilities and Institutions for Mental Diseases § 456.606 Frequency of inspections. The team and the agency...

42 CFR 456.607 - Notification before inspection.

Code of Federal Regulations, 2013 CFR

2013-10-01

....607 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS UTILIZATION CONTROL Inspections of Care in Intermediate Care Facilities and Institutions for Mental Diseases § 456.607 Notification before inspection. No facility may be...

Consistency of the New York State bridge inspection program.

DOT National Transportation Integrated Search

2013-09-01

The New York State Department of Transportation (NYSDOT) maintains an inventory of over 17,000 highway : bridges across the state. As per New York States Uniform Code of Bridge Inspections, all bridges in New York : State are inspected biennially,...

Reliability, factor analysis and internal consistency calculation of the Insomnia Severity Index (ISI) in French and in English among Lebanese adolescents.

PubMed

Chahoud, M; Chahine, R; Salameh, P; Sauleau, E A

2017-06-01

Our goal is to validate and to verify the reliability of the French and English versions of the Insomnia Severity Index (ISI) in Lebanese adolescents. A cross-sectional study was implemented. 104 Lebanese students aged between 14 and 19 years participated in the study. The English version of the questionnaire was distributed to English-speaking students and the French version was administered to French-speaking students. A scale (1 to 7 with 1 = very well understood and 7 = not at all) was used to identify the level of the students' understanding of each instruction, question and answer of the ISI. The scale's structural validity was assessed. The factor structure of ISI was evaluated by principal component analysis. The internal consistency of this scale was evaluated by Cronbach's alpha. To assess test-retest reliability the intraclass correlation coefficient (ICC) was used. The principal component analysis confirmed the presence of a two-component factor structure in the English version and a three-component factor structure in the French version with eigenvalues > 1. The English version of the ISI had an excellent internal consistency (α = 0.90), while the French version had a good internal consistency (α = 0.70). The ICC presented an excellent agreement in the French version (ICC = 0.914, CI = 0.856-0.949) and a good agreement in the English one (ICC = 0.762, CI = 0.481-890). The Bland-Altman plots of the two versions of the ISI showed that the responses over two weeks' were comparable and very few outliers were detected. The results of our analyses reveal that both English and French versions of the ISI scale have good internal consistency and are reproducible and reliable. Therefore, it can be used to assess the prevalence of insomnia in Lebanese adolescents.

Bone-Breaking Bite Force of Basilosaurus isis (Mammalia, Cetacea) from the Late Eocene of Egypt Estimated by Finite Element Analysis

PubMed Central

Snively, Eric; Fahlke, Julia M.; Welsh, Robert C.

2015-01-01

Bite marks suggest that the late Eocence archaeocete whale Basilosaurus isis (Birket Qarun Formation, Egypt) fed upon juveniles of the contemporary basilosaurid Dorudon atrox. Finite element analysis (FEA) of a nearly complete adult cranium of B. isis enables estimates of its bite force and tests the animal’s capabilities for crushing bone. Two loadcases reflect different biting scenarios: 1) an intitial closing phase, with all adductors active and a full condylar reaction force; and 2) a shearing phase, with the posterior temporalis active and minimized condylar force. The latter is considered probable when the jaws were nearly closed because the preserved jaws do not articulate as the molariform teeth come into occulusion. Reaction forces with all muscles active indicate that B. isis maintained relatively greater bite force anteriorly than seen in large crocodilians, and exerted a maximum bite force of at least 16,400 N at its upper P3. Under the shearing scenario with minimized condylar forces, tooth reaction forces could exceed 20,000 N despite lower magnitudes of muscle force. These bite forces at the teeth are consistent with bone indentations on Dorudon crania, reatract-and-shear hypotheses of Basilosaurus bite function, and seizure of prey by anterior teeth as proposed for other archaeocetes. The whale’s bite forces match those estimated for pliosaurus when skull lengths are equalized, suggesting similar tradeoffs of bite function and hydrodynamics. Reaction forces in B. isis were lower than maxima estimated for large crocodylians and carnivorous dinosaurs. However, comparison of force estimates from FEA and regression data indicate that B. isis exerted the largest bite forces yet estimated for any mammal, and greater force than expected from its skull width. Cephalic feeding biomechanics of Basilosaurus isis are thus consistent with habitual predation. PMID:25714832

ISIS 301012 gene therapy for hypercholesterolemia: sense, antisense, or nonsense?

PubMed

Ito, Matthew K

2007-10-01

To present an overview of antisense technology and to review and assess available literature on the chemistry, pharmacology, pharmacokinetics, drug interactions, preclinical and clinical studies, dosing, and adverse events of ISIS 301012 in the treatment of hyperlipidemia. PubMed database searches were conducted from 1966 to May 2007 using the search terms ISIS 301012, antisense, oligonucleotide, hypercholesterolemia, hyperlipidemia, and apolipoprotein B. Bibliographies of relevant review articles and information from the manufacturer were reviewed for additional references. Available English-language literature, including abstracts, preclinical, and clinical trials, review articles, and scientific presentations were examined. Apolipoprotein B is an important structural protein on the surface of atherogenic lipoproteins such as remnant very-low-density lipoprotein and low-density lipoprotein and facilitates the clearance of these particles from the circulation by binding to the low-density lipoprotein receptor. Overproduction of apolipoprotein B or reduced receptor-mediated clearance of lipoproteins leads to elevated serum cholesterol levels and premature atherosclerosis. ISIS 301012 is an antisense oligonucleotide that inhibits apolipoprotein B production by binding directly to and reducing the expression of apolipoprotein B messenger RNA. In a clinical trial, ISIS 301012 50-400 mg administered weekly via subcutaneous injection for 4 weeks reduced apolipoprotein B by 14.3-47.4% and low-density lipoprotein cholesterol by 5.9-40% at 55 days. The most frequent adverse event was injection-site erythema that resolved spontaneously. Studies are ongoing to further define the safety, efficacy, and pharmacokinetics of ISIS 301012 as add-on therapy in patients with heterozygous and homozygous familial hypercholesterolemia. No pharmacokinetic interactions have been demonstrated with ezetimibe and simvastatin. ISIS 301012 is the first agent to enter clinical trials utilizing an antisense mechanism for reducing the production of apolipoprotein B. Further studies are needed to verify its safety, efficacy, and position of therapy in the dyslipidemic patient.

Application of Statistical Quality Control Techniques to Detonator Fabrication: Feasibility Study

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jones, J. Frank

1971-05-20

A feasibility study was performed on the use of process control techniques which might reduce the need for a duplicate inspection by production inspection and quality control inspection. Two active detonator fabrication programs were selected for the study. Inspection areas accounting for the greatest percentage of total inspection costs were selected by applying "Pareto's Principle of Maldistribution." Data from these areas were then gathered and analyzed by a process capabiltiy study.

9 CFR 307.1 - Facilities for Program employees.

Code of Federal Regulations, 2014 CFR

2014-01-01

... INSPECTION AND CERTIFICATION FACILITIES FOR INSPECTION § 307.1 Facilities for Program employees. Office space... employees assigned thereto. The space set aside for this purpose shall meet with approval of the circuit... facilities exist in a nearby convenient location. Laundry service for inspectors' outer work clothing shall...

40 CFR 763.98 - Waiver; delegation to State.

Code of Federal Regulations, 2014 CFR

2014-07-01

... CONTROL ACT ASBESTOS Asbestos-Containing Materials in Schools § 763.98 Waiver; delegation to State. (a... implement a program of asbestos inspection and management that contains requirements that are at least as... provisions or proposed provisions relating to its program of asbestos inspection and management in schools...

40 CFR 763.98 - Waiver; delegation to State.

Code of Federal Regulations, 2010 CFR

2010-07-01

... CONTROL ACT ASBESTOS Asbestos-Containing Materials in Schools § 763.98 Waiver; delegation to State. (a... implement a program of asbestos inspection and management that contains requirements that are at least as... provisions or proposed provisions relating to its program of asbestos inspection and management in schools...

40 CFR 763.98 - Waiver; delegation to State.

Code of Federal Regulations, 2011 CFR

2011-07-01

... CONTROL ACT ASBESTOS Asbestos-Containing Materials in Schools § 763.98 Waiver; delegation to State. (a... implement a program of asbestos inspection and management that contains requirements that are at least as... provisions or proposed provisions relating to its program of asbestos inspection and management in schools...

40 CFR 763.98 - Waiver; delegation to State.

Code of Federal Regulations, 2012 CFR

2012-07-01

... CONTROL ACT ASBESTOS Asbestos-Containing Materials in Schools § 763.98 Waiver; delegation to State. (a... implement a program of asbestos inspection and management that contains requirements that are at least as... provisions or proposed provisions relating to its program of asbestos inspection and management in schools...

40 CFR 763.98 - Waiver; delegation to State.

Code of Federal Regulations, 2013 CFR

2013-07-01

... CONTROL ACT ASBESTOS Asbestos-Containing Materials in Schools § 763.98 Waiver; delegation to State. (a... implement a program of asbestos inspection and management that contains requirements that are at least as... provisions or proposed provisions relating to its program of asbestos inspection and management in schools...

The principles of HACCP.

USDA-ARS?s Scientific Manuscript database

The Hazard Analysis and Critical Control Point (HACCP) food safety inspection program is utilized by both USDA Food Safety Inspection Service (FSIS) and FDA for many of the products they regulate. This science-based program was implemented by the USDA FSIS to enhance the food safety of meat and pou...

49 CFR 217.9 - Program of operational tests and inspections; recordkeeping.

Code of Federal Regulations, 2014 CFR

2014-10-01

... controls accessibility to such information retained in its electronic database system and identifies those... inspections required by this section, the Associate Administrator for Safety may, for cause stated, disapprove... disapproval decision. If the Associate Administrator for Safety disapproves the program, (1) The railroad has...

49 CFR 217.9 - Program of operational tests and inspections; recordkeeping.

Code of Federal Regulations, 2010 CFR

2010-10-01

... controls accessibility to such information retained in its electronic database system and identifies those... inspections required by this section, the Associate Administrator for Safety may, for cause stated, disapprove... disapproval decision. If the Associate Administrator for Safety disapproves the program, (1) The railroad has...

49 CFR 217.9 - Program of operational tests and inspections; recordkeeping.

Code of Federal Regulations, 2011 CFR

2011-10-01

... controls accessibility to such information retained in its electronic database system and identifies those... inspections required by this section, the Associate Administrator for Safety may, for cause stated, disapprove... disapproval decision. If the Associate Administrator for Safety disapproves the program, (1) The railroad has...

49 CFR 217.9 - Program of operational tests and inspections; recordkeeping.

Code of Federal Regulations, 2012 CFR

2012-10-01

... controls accessibility to such information retained in its electronic database system and identifies those... inspections required by this section, the Associate Administrator for Safety may, for cause stated, disapprove... disapproval decision. If the Associate Administrator for Safety disapproves the program, (1) The railroad has...

On dependency properties of the ISIs generated by a two-compartmental neuronal model.

PubMed

Benedetto, Elisa; Sacerdote, Laura

2013-02-01

One-dimensional leaky integrate and fire neuronal models describe interspike intervals (ISIs) of a neuron as a renewal process and disregarding the neuron geometry. Many multi-compartment models account for the geometrical features of the neuron but are too complex for their mathematical tractability. Leaky integrate and fire two-compartment models seem a good compromise between mathematical tractability and an improved realism. They indeed allow to relax the renewal hypothesis, typical of one-dimensional models, without introducing too strong mathematical difficulties. Here, we pursue the analysis of the two-compartment model studied by Lansky and Rodriguez (Phys D 132:267-286, 1999), aiming of introducing some specific mathematical results used together with simulation techniques. With the aid of these methods, we investigate dependency properties of ISIs for different values of the model parameters. We show that an increase of the input increases the strength of the dependence between successive ISIs.

Practical Formal Verification of MPI and Thread Programs

NASA Astrophysics Data System (ADS)

Gopalakrishnan, Ganesh; Kirby, Robert M.

Large-scale simulation codes in science and engineering are written using the Message Passing Interface (MPI). Shared memory threads are widely used directly, or to implement higher level programming abstractions. Traditional debugging methods for MPI or thread programs are incapable of providing useful formal guarantees about coverage. They get bogged down in the sheer number of interleavings (schedules), often missing shallow bugs. In this tutorial we will introduce two practical formal verification tools: ISP (for MPI C programs) and Inspect (for Pthread C programs). Unlike other formal verification tools, ISP and Inspect run directly on user source codes (much like a debugger). They pursue only the relevant set of process interleavings, using our own customized Dynamic Partial Order Reduction algorithms. For a given test harness, DPOR allows these tools to guarantee the absence of deadlocks, instrumented MPI object leaks and communication races (using ISP), and shared memory races (using Inspect). ISP and Inspect have been used to verify large pieces of code: in excess of 10,000 lines of MPI/C for ISP in under 5 seconds, and about 5,000 lines of Pthread/C code in a few hours (and much faster with the use of a cluster or by exploiting special cases such as symmetry) for Inspect. We will also demonstrate the Microsoft Visual Studio and Eclipse Parallel Tools Platform integrations of ISP (these will be available on the LiveCD).

Building a Discourse-Tagged Corpus in the Framework of Rhetorical Structure Theory

DTIC Science & Technology

2001-01-01

lmcarlnord@aol.com Daniel Marcu Information Sciences Institute University of S . California Marina del Rey, CA 90292 marcu@isi.edu Mary Ellen Okurowski...Rhetorical Structure Theory 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK...UNIT NUMBER 7. PERFORMING ORGANIZATION NAME( S ) AND ADDRESS(ES) Department of Defense,9800 Savage Road,Fort Meade,MD,20755 8. PERFORMING

Department of Defense In-House RDT&E Activities

DTIC Science & Technology

1979-10-30

OIVAI .. I-:JNLI’IONS/EQJIPMtN’r/CAPAt3ILIrflt.4 tNC’i4PAb-Eý, APPLO RUA INCL WRC DEV AND) SPT IN INTI:RLO got: ~ISI6 ANALYSIS. JAM,IJEtPSi(7 iNrt7L...LU*. CAPT. R. 4. tsROWN TECH1.L1R. MR. THOMAS RAMIREZ F. ~PROGRAM LJATA BY FISCAL YEAR (MILLION S PiKOtRAM 1979 IQ80fk~(ACTUJAL) (ACT + EsT) TUTAL

ANNUAL RADIOACTIVE WASTE TANK INSPECTION PROGRAM 2009

DOE Office of Scientific and Technical Information (OSTI.GOV)

West, B.; Waltz, R.

2010-06-21

Aqueous radioactive wastes from Savannah River Site (SRS) separations and vitrification processes are contained in large underground carbon steel tanks. Inspections made during 2009 to evaluate these vessels and other waste handling facilities along with evaluations based on data from previous inspections are the subject of this report. The 2009 inspection program revealed that the structural integrity and waste confinement capability of the Savannah River Site waste tanks were maintained. All inspections scheduled per LWO-LWE-2008-00423, HLW Tank Farm Inspection Plan for 2009, were completed. All Ultrasonic measurements (UT) performed in 2009 met the requirements of C-ESG-00006, In-Service Inspection Program formore » High Level Waste Tanks, Rev. 1, and WSRC-TR-2002-00061, Rev.4. UT inspections were performed on Tank 29 and the findings are documented in SRNL-STI-2009-00559, Tank Inspection NDE Results for Fiscal Year 2009, Waste Tank 29. Post chemical cleaning UT measurements were made in Tank 6 and the results are documented in SRNL-STI-2009-00560, Tank Inspection NDE Results Tank 6, Including Summary of Waste Removal Support Activities in Tanks 5 and 6. A total of 6669 photographs were made and 1276 visual and video inspections were performed during 2009. Twenty-Two new leaksites were identified in 2009. The locations of these leaksites are documented in C-ESR-G-00003, SRS High Level Waste Tank Leaksite Information, Rev.4. Fifteen leaksites at Tank 5 were documented during tank wall/annulus cleaning activities. Five leaksites at Tank 6 were documented during tank wall/annulus cleaning activities. Two new leaksites were identified at Tank 19 during waste removal activities. Previously documented leaksites were reactivated at Tanks 5 and 12 during waste removal activities. Also, a very small amount of additional leakage from a previously identified leaksite at Tank 14 was observed.« less

Continental United States Military Housing Inspection National Capital Region

DTIC Science & Technology

2015-08-13

that was flaking, peeling, or chalking. JBAB did not have an asbestos management program, plan, or an appointed asbestos program manager...housing partner to ensure inspection and maintenance plan is achieved; and • Implement an asbestos management plan and appoint an asbestos program...select environmental health and safety requirements, such as those for drinking water, radon, asbestos , and lead based paint. We conducted this

Semiannual versus annual motor vehicle inspection : an evaluation of the literature and a benefit-cost analysis.

DOT National Transportation Integrated Search

1978-01-01

The purpose of this report is to provide information comparing semiannual motor vehicle inspection systems with annual inspection systems. A review of the literature dealing with the similarities and differences between semiannual and annual programs...

7 CFR 1779.12 - Inspections.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 12 2010-01-01 2010-01-01 false Inspections. 1779.12 Section 1779.12 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE (CONTINUED) WATER AND WASTE DISPOSAL PROGRAMS GUARANTEED LOANS § 1779.12 Inspections. The lender will notify...

42 CFR 456.614 - Inspections by utilization review committee.

Code of Federal Regulations, 2011 CFR

2011-10-01

....614 Section 456.614 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS UTILIZATION CONTROL Inspections of Care in Intermediate Care Facilities and Institutions for Mental Diseases § 456.614 Inspections by utilization review...

42 CFR 456.614 - Inspections by utilization review committee.

Code of Federal Regulations, 2013 CFR

2013-10-01

....614 Section 456.614 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS UTILIZATION CONTROL Inspections of Care in Intermediate Care Facilities and Institutions for Mental Diseases § 456.614 Inspections by utilization review...

42 CFR 456.611 - Reports on inspections.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS UTILIZATION CONTROL Inspections of Care in Intermediate Care Facilities and Institutions for Mental Diseases § 456.611 Reports on inspections. (a) The team must submit a...

42 CFR 456.611 - Reports on inspections.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS UTILIZATION CONTROL Inspections of Care in Intermediate Care Facilities and Institutions for Mental Diseases § 456.611 Reports on inspections. (a) The team must submit a...

42 CFR 456.611 - Reports on inspections.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS UTILIZATION CONTROL Inspections of Care in Intermediate Care Facilities and Institutions for Mental Diseases § 456.611 Reports on inspections. (a) The team must submit a...

42 CFR 456.614 - Inspections by utilization review committee.

Code of Federal Regulations, 2014 CFR

2014-10-01

....614 Section 456.614 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS UTILIZATION CONTROL Inspections of Care in Intermediate Care Facilities and Institutions for Mental Diseases § 456.614 Inspections by utilization review...

42 CFR 456.611 - Reports on inspections.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS UTILIZATION CONTROL Inspections of Care in Intermediate Care Facilities and Institutions for Mental Diseases § 456.611 Reports on inspections. (a) The team must submit a...

42 CFR 456.614 - Inspections by utilization review committee.

Code of Federal Regulations, 2012 CFR

2012-10-01

....614 Section 456.614 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS UTILIZATION CONTROL Inspections of Care in Intermediate Care Facilities and Institutions for Mental Diseases § 456.614 Inspections by utilization review...

24 CFR 891.180 - Physical condition standards; physical inspection requirements.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 4 2013-04-01 2013-04-01 false Physical condition standards; physical inspection requirements. 891.180 Section 891.180 Housing and Urban Development REGULATIONS... DISABILITIES General Program Requirements § 891.180 Physical condition standards; physical inspection...

24 CFR 891.180 - Physical condition standards; physical inspection requirements.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false Physical condition standards; physical inspection requirements. 891.180 Section 891.180 Housing and Urban Development REGULATIONS... DISABILITIES General Program Requirements § 891.180 Physical condition standards; physical inspection...

24 CFR 891.180 - Physical condition standards; physical inspection requirements.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Physical condition standards; physical inspection requirements. 891.180 Section 891.180 Housing and Urban Development Regulations... DISABILITIES General Program Requirements § 891.180 Physical condition standards; physical inspection...

24 CFR 891.180 - Physical condition standards; physical inspection requirements.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 4 2014-04-01 2014-04-01 false Physical condition standards; physical inspection requirements. 891.180 Section 891.180 Housing and Urban Development REGULATIONS... DISABILITIES General Program Requirements § 891.180 Physical condition standards; physical inspection...

24 CFR 891.180 - Physical condition standards; physical inspection requirements.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 4 2012-04-01 2012-04-01 false Physical condition standards; physical inspection requirements. 891.180 Section 891.180 Housing and Urban Development REGULATIONS... DISABILITIES General Program Requirements § 891.180 Physical condition standards; physical inspection...

10 CFR 71.121 - Internal inspection.

Code of Federal Regulations, 2013 CFR

2013-01-01

... performed for each work operation where necessary to assure quality. If direct inspection of processed... REGULATORY COMMISSION (CONTINUED) PACKAGING AND TRANSPORTATION OF RADIOACTIVE MATERIAL Quality Assurance § 71... execute a program for inspection of activities affecting quality by or for the organization performing the...

10 CFR 71.121 - Internal inspection.

Code of Federal Regulations, 2012 CFR

2012-01-01

... performed for each work operation where necessary to assure quality. If direct inspection of processed... REGULATORY COMMISSION (CONTINUED) PACKAGING AND TRANSPORTATION OF RADIOACTIVE MATERIAL Quality Assurance § 71... execute a program for inspection of activities affecting quality by or for the organization performing the...

10 CFR 71.121 - Internal inspection.

Code of Federal Regulations, 2011 CFR

2011-01-01

... performed for each work operation where necessary to assure quality. If direct inspection of processed... REGULATORY COMMISSION (CONTINUED) PACKAGING AND TRANSPORTATION OF RADIOACTIVE MATERIAL Quality Assurance § 71... execute a program for inspection of activities affecting quality by or for the organization performing the...

10 CFR 71.121 - Internal inspection.

Code of Federal Regulations, 2014 CFR

2014-01-01

... performed for each work operation where necessary to assure quality. If direct inspection of processed... REGULATORY COMMISSION (CONTINUED) PACKAGING AND TRANSPORTATION OF RADIOACTIVE MATERIAL Quality Assurance § 71... execute a program for inspection of activities affecting quality by or for the organization performing the...

10 CFR 71.121 - Internal inspection.

Code of Federal Regulations, 2010 CFR

2010-01-01

... performed for each work operation where necessary to assure quality. If direct inspection of processed... REGULATORY COMMISSION (CONTINUED) PACKAGING AND TRANSPORTATION OF RADIOACTIVE MATERIAL Quality Assurance § 71... execute a program for inspection of activities affecting quality by or for the organization performing the...

Psychometric properties of the Sleep Condition Indicator and Insomnia Severity Index in the evaluation of insomnia disorder.

PubMed

Wong, Mark Lawrence; Lau, Kristy Nga Ting; Espie, Colin A; Luik, Annemarie I; Kyle, Simon D; Lau, Esther Yuet Ying

2017-05-01

The Sleep Condition Indicator (SCI) and Insomnia Severity Index (ISI) are commonly used instruments to assess insomnia. We evaluated their psychometric properties, particularly their discriminant validity against structured clinical interview (according to DSM-5 and ICSD-3), and their concurrent validity with measures of sleep and daytime functioning. A total of 158 young adults, 16% of whom were diagnosed with DSM-5 insomnia disorder and 13% with ICSD-3 Chronic Insomnia by structured interview, completed the ISI and SCI twice in 7-14 days, in addition to measures of sleep and daytime function. The Chinese version of the SCI was validated with good psychometric properties (ICC = 0.882). A cutoff of ≥8 on the ISI, ≤5 on the SCI short form, and ≤21 on the SCI achieved high discriminant validity (AUC > 0.85) in identifying individuals with insomnia based on both DSM-5 and ICSD-3 criteria. The SCI and ISI had comparable associations with subjective (0.18 < r < 0.51) and actigraphic sleep (0.31 < r < 0.43) and daytime functioning (0.34 < r < 0.53). The SCI, SCI short form, and ISI were found to correctly identify individuals with DSM-5- and ICSD-3-defined insomnia disorder. Moreover, they showed good concordance with measures of daytime dysfunction, as well as subjective and objective sleep. The SCI and ISI are recommended for use in clinical and research settings. Copyright © 2016 Elsevier B.V. All rights reserved.

Electron Density Profiles of the Topside Ionosphere

NASA Technical Reports Server (NTRS)

Huang, Xue-Qin; Reinsch, Bodo W.; Bilitza, Dieter; Benson, Robert F.

2002-01-01

The existing uncertainties about the electron density profiles in the topside ionosphere, i.e., in the height region from h,F2 to - 2000 km, require the search for new data sources. The ISIS and Alouette topside sounder satellites from the sixties to the eighties recorded millions of ionograms but most were not analyzed in terms of electron density profiles. In recent years an effort started to digitize the analog recordings to prepare the ionograms for computerized analysis. As of November 2001 about 350000 ionograms have been digitized from the original 7-track analog tapes. These data are available in binary and CDF format from the anonymous ftp site of the National Space Science Data Center. A search site and browse capabilities on CDAWeb assist the scientific usage of these data. All information and access links can be found at http://nssdc.gsfc.nasa.gov/space/isis/isis- status.htm1. This paper describes the ISIS data restoration effort and shows how the digital ionograms are automatically processed into electron density profiles from satellite orbit altitude (1400 km for ISIS-2) down to the F peak. Because of the large volume of data an automated processing algorithm is imperative. The TOPside Ionogram Scaler with True height algorithm TOPIST software developed for this task is successfully scaling - 70% of the ionograms. An <> is available to manually scale the more difficult ionograms. The automated processing of the digitized ISIS ionograms is now underway, producing a much-needed database of topside electron density profiles for ionospheric modeling covering more than one solar cycle.

Defect inspection and printability study for 14 nm node and beyond photomask

NASA Astrophysics Data System (ADS)

Seki, Kazunori; Yonetani, Masashi; Badger, Karen; Dechene, Dan J.; Akima, Shinji

2016-10-01

Two different mask inspection techniques are developed and compared for 14 nm node and beyond photomasks, High resolution and Litho-based inspection. High resolution inspection is the general inspection method in which a 19x nm wavelength laser is used with the High NA inspection optics. Litho-based inspection is a new inspection technology. This inspection uses the wafer lithography information, and as such, this method has automatic defect classification capability which is based on wafer printability. Both High resolution and Litho-based inspection methods are compared using 14 nm and 7 nm node programmed defect and production design masks. The defect sensitivity and mask inspectability is compared, in addition to comparing the defect classification and throughput. Additionally, the Cost / Infrastructure comparison is analyzed and the impact of each inspection method is discussed.

40 CFR 282.88 - Pennsylvania State-Administered Program.

Code of Federal Regulations, 2010 CFR

2010-07-01

... actions, as well as in accordance with other statutory and regulatory provisions. (c) To retain program....C.P. Rule 2329Action of Court on Petition Pa R.C.P. Rule 2330Practice (iii) The following statutory... contaminated materials) Section 245.411Inspection frequency (insofar as the section addresses inspections by...

76 FR 66763 - Models for Plant-Specific Adoption of Technical Specifications Task Force Traveler TSTF-510...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-27

... of Technical Specifications Task Force Traveler TSTF-510, Revision 2, ``Revision to Steam Generator..., Revision 2, ``Revision to Steam Generator [(SG)] Program Inspection Frequencies and Tube Sample Selection..., ``Steam Generator (SG) Program,'' Specification 5.6.7, ``Steam Generator Tube Inspection Report,'' and the...

PDES Application Protocol Suite for Composites (PAS-C). Functional Needs Report for the PAS-C Program

DTIC Science & Technology

1991-09-01

103 A2352344 Layup Cover Sheets/Inspect ............................. 103 A2352345 Perform Automated Tape Laying operations...A2352345 Perform Automated Tape Laying operations/Inspect The tape is layed in 3-12 inch strips along the surface of the bond mold. The NC program is

25 CFR 170.504 - When and how are bridge inspections performed?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false When and how are bridge inspections performed? 170.504 Section 170.504 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER INDIAN RESERVATION ROADS PROGRAM Planning, Design, and Construction of Indian Reservation Roads Program Facilities...

25 CFR 170.507 - Who reviews bridge inspection reports?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false Who reviews bridge inspection reports? 170.507 Section 170.507 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER INDIAN RESERVATION ROADS PROGRAM Planning, Design, and Construction of Indian Reservation Roads Program Facilities Bridge...

25 CFR 170.505 - How must bridge inspections be coordinated?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false How must bridge inspections be coordinated? 170.505 Section 170.505 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER INDIAN RESERVATION ROADS PROGRAM Planning, Design, and Construction of Indian Reservation Roads Program Facilities...

46 CFR 115.630 - The Alternative Hull Examination (AHE) Program application.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false The Alternative Hull Examination (AHE) Program... PASSENGERS INSPECTION AND CERTIFICATION Hull and Tailshaft Examinations § 115.630 The Alternative Hull... hull examination date to the Officer in Charge, Marine Inspection (OCMI) who will oversee the survey...

9 CFR 592.340 - Supervision of marking and packaging.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 9 Animals and Animal Products 2 2014-01-01 2014-01-01 false Supervision of marking and packaging... § 592.340 Supervision of marking and packaging. (a) Evidence of label approval. Inspection program... product or container thereof except by an inspection program employee or under the supervision of an...

9 CFR 592.340 - Supervision of marking and packaging.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Supervision of marking and packaging... § 592.340 Supervision of marking and packaging. (a) Evidence of label approval. Inspection program... product or container thereof except by an inspection program employee or under the supervision of an...

9 CFR 592.340 - Supervision of marking and packaging.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false Supervision of marking and packaging... § 592.340 Supervision of marking and packaging. (a) Evidence of label approval. Inspection program... product or container thereof except by an inspection program employee or under the supervision of an...

9 CFR 592.340 - Supervision of marking and packaging.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Supervision of marking and packaging... § 592.340 Supervision of marking and packaging. (a) Evidence of label approval. Inspection program... product or container thereof except by an inspection program employee or under the supervision of an...

9 CFR 592.340 - Supervision of marking and packaging.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Supervision of marking and packaging... § 592.340 Supervision of marking and packaging. (a) Evidence of label approval. Inspection program... product or container thereof except by an inspection program employee or under the supervision of an...

Early Warning Report: Use of Contractors to Conduct Clean Air Act Risk Management Program Inspections in Certain States Goes Against Court Decisions

EPA Pesticide Factsheets

Report #12-P-0376, March 28, 2012. The OIG is currently evaluating whether the EPA has adequate management controls for ensuring the effectiveness of its Clean Air Act (CAA) Section 112(r) risk management program inspections.

A New Approach to Create Image Control Networks in ISIS

NASA Astrophysics Data System (ADS)

Becker, K. J.; Berry, K. L.; Mapel, J. A.; Walldren, J. C.

2017-06-01

A new approach was used to create a feature-based control point network that required the development of new tools in the Integrated Software for Imagers and Spectrometers (ISIS3) system to process very large datasets.

Pipe degradation investigations for optimization of flow-accelerated corrosion inspection location selection

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chandra, S.; Habicht, P.; Chexal, B.

1995-12-01

A large amount of piping in a typical nuclear power plant is susceptible to Flow-Accelerated Corrosion (FAC) wall thinning to varying degrees. A typical PAC monitoring program includes the wall thickness measurement of a select number of components in order to judge the structural integrity of entire systems. In order to appropriately allocate resources and maintain an adequate FAC program, it is necessary to optimize the selection of components for inspection by focusing on those components which provide the best indication of system susceptibility to FAC. A better understanding of system FAC predictability and the types of FAC damage encounteredmore » can provide some of the insight needed to better focus and optimize the inspection plan for an upcoming refueling outage. Laboratory examination of FAC damaged components removed from service at Northeast Utilities` (NU) nuclear power plants provides a better understanding of the damage mechanisms involved and contributing causes. Selected results of this ongoing study are presented with specific conclusions which will help NU to better focus inspections and thus optimize the ongoing FAC inspection program.« less

The Duration of Auditory Sensory Memory for Vowel Processing: Neurophysiological and Behavioral Measures.

PubMed

Yu, Yan H; Shafer, Valerie L; Sussman, Elyse S

2018-01-01

Speech perception behavioral research suggests that rates of sensory memory decay are dependent on stimulus properties at more than one level (e.g., acoustic level, phonemic level). The neurophysiology of sensory memory decay rate has rarely been examined in the context of speech processing. In a lexical tone study, we showed that long-term memory representation of lexical tone slows the decay rate of sensory memory for these tones. Here, we tested the hypothesis that long-term memory representation of vowels slows the rate of auditory sensory memory decay in a similar way to that of lexical tone. Event-related potential (ERP) responses were recorded to Mandarin non-words contrasting the vowels /i/ vs. /u/ and /y/ vs. /u/ from first-language (L1) Mandarin and L1 American English participants under short and long interstimulus interval (ISI) conditions (short ISI: an average of 575 ms, long ISI: an average of 2675 ms). Results revealed poorer discrimination of the vowel contrasts for English listeners than Mandarin listeners, but with different patterns for behavioral perception and neural discrimination. As predicted, English listeners showed the poorest discrimination and identification for the vowel contrast /y/ vs. /u/, and poorer performance in the long ISI condition. In contrast to Yu et al. (2017), however, we found no effect of ISI reflected in the neural responses, specifically the mismatch negativity (MMN), P3a and late negativity ERP amplitudes. We did see a language group effect, with Mandarin listeners generally showing larger MMN and English listeners showing larger P3a. The behavioral results revealed that native language experience plays a role in echoic sensory memory trace maintenance, but the failure to find an effect of ISI on the ERP results suggests that vowel and lexical tone memory traces decay at different rates. Highlights : We examined the interaction between auditory sensory memory decay and language experience. We compared MMN, P3a, LN and behavioral responses in short vs. long interstimulus intervals. We found that different from lexical tone contrast, MMN, P3a, and LN changes to vowel contrasts are not influenced by lengthening the ISI to 2.6 s. We also found that the English listeners discriminated the non-native vowel contrast with lower accuracy under the long ISI condition.

Proceedings of the International Workshop on Current Challenges in Liquid and Glass Science, (The Cosener's House, Abingdon 10-12 January 2007).

PubMed

Hannon, Alex C; Salmon, Philip S; Soper, Alan K

2007-10-17

The workshop was held to discuss current experimental and theoretical challenges in liquid and glass science and to honour the contribution made by Spencer Howells (ISIS, UK) to the field of neutron scattering from liquids and glasses. The meeting was attended by 70 experimentalists, theorists and computer simulators from Europe, Japan and North America and comprised 34 oral presentations together with two lively poster sessions. Three major themes were discussed, namely (i) the glass transition and properties of liquids and glasses under extreme conditions; (ii) the complementarity of neutron and x-ray scattering techniques with other experimental methods; and (iii) the modelling of liquid and glass structure. These themes served to highlight (a) recent advances in neutron and x-ray instrumentation used to investigate liquid and glassy materials under extreme conditions; (b) the relationship between the results obtained from different experimental and theoretical/computational methods; and (c) the modern methods used to interpret experimental results. The presentations ranged from polyamorphism in liquids and glasses to protein folding in aqueous solution and included the dynamics of fresh and freeze-dried strawberries and red onions. The properties of liquid phosphorus were also memorably demonstrated! The formal highlight was the 'Spencerfest' dinner where Neil Cowlam (Sheffield, UK) gave an excellent after dinner speech. The organisation of the workshop benefited tremendously from the secretarial skills of Carole Denning (ISIS, UK). The financial support of the Council for the Central Laboratory of the Research Councils (CCLRC), the Liquids and Complex Fluids Group of the Institute of Physics, The ISIS Disordered Materials Group, the CCLRC Centre for Materials Physics and Chemistry and the CCLRC Centre for Molecular Structure and Dynamics is gratefully acknowledged. Finally, it is a pleasure to thank all the workshop participants whose lively contributions led to the success of the meeting. The present special issue stems from the interest of many of those present to collect their work into a single volume. [Formula: see text] The workshop participants. Spencer Howells is in the centre of the front row. DEDICATION William Spencer Howells It is a great pleasure to dedicate this Special Issue on Current Challenges in Liquid and Glass Science to the many contributions Spencer Howells has made to the structure and dynamics of liquids and glasses over some 40 years of work with the neutron scattering technique. After completing a first degree in Physics at Cambridge in 1966, Spencer started a postgraduate program with Gordon Squires at Cambridge, exploiting the early neutron scattering instrumentation that was available in those days at the Harwell reactors. This resulted in a Ph D thesis in 1970 on the twin topics of 'Neutron scattering of phonons in single-crystal molybdenum, using a time-of-flight chopper spectrometer (Part I)' and 'Neutron studies of the metal-insulator transition (Part II)'. The thesis was split into two parts because the hydrogen moderator blew-up on the chopper instrument used for the first part! From Cambridge, he moved to Leicester University as a post-doctoral Fellow with John Enderby, who was setting up a programme of study on the liquid state of matter. Here Spencer continued to use the Harwell Dido reactor, now to measure the structure of liquid metal alloys and molten salts - a topic that has kept his interest right through into retirement. He also initiated the first structural studies of aqueous solutions using neutron scattering, eventually pursuing this work as one of the first UK users of the Institut Laue-Langevin, Grenoble, France (ILL). In 1973 Spencer moved to the ILL, which was then and has remained the world's leading steady-state neutron source, as instrument scientist on IN10, the quasi-elastic neutron scattering beam line. Here he led the field in developing the quasi-elastic technique and new quasi-elastic scattering experiments were begun on the dynamics of aqueous solutions. At the same time he was local contact for most of the UK users of the liquids diffractometer D4, often providing excellent hospitality to hungry and thirsty Ph D students, in addition to his scientific support! After the ILL he moved, in 1978, to the Spallation Neutron Source (SNS), later called ISIS, where he was responsible for building the Liquids and Amorphous Diffractometer, LAD. This was a tricky undertaking as there were no neutrons at the SNS until 1984, so initial testing of LAD was done on the Harwell Linac. He also worked on the design and specification of the SNS moderators and collimation, and his design for the neutron collimator is still in use at ISIS today. The initial design and build of the Small Angle Neutron Diffractometer for Amorphous and Liquid Samples (SANDALS) was undertaken in this period, and Spencer had a major impact on the development of the ATLAS software used to analyse diffraction data from disordered materials. He was also involved in the design of IRIS, the first quasi-elastic spectrometer at ISIS. As more people joined in liquids and amorphous materials research at ISIS, Spencer was able to diversify, and he took an increasing interest in the application of IRIS to liquid materials. Here he brought his expertise in data analysis from the ILL and LAD and applied it to the time-of-flight quasi-elastic technique. The suite of data analysis programs that evolved, called IDA, was enlarged to encompass quasi-elastic neutron scattering data taken on a number of ISIS and non-ISIS instruments, including OSIRIS, HET, and MARI (at ISIS), IN5, IN6, IN10, IN13 and IN16 (at ILL) and NEAT (at HMI, Berlin). At the same time, Spencer's penchant for working on computers meant he took an increasingly important role in setting up and running the ISIS user database and proposal system, which continued for many years until his retirement in 2004. He also became full-time instrument scientist on IRIS and even after retirement he continues to work on developing data analysis software for this instrument. In the course of his career Spencer Howells has so far produced more than 200 scientific publications, covering a broad spectrum of topics. Recent examples include 'Dynamics of fresh and freeze-dried strawberry and red onion: quasielastic neutron scattering.' and 'The structure and dynamics of 2-dimensional fluids in swelling clays', to illustrate some of the range of his science. This work has gone hand in hand with comprehensive support for users at the ILL, ISIS and elsewhere, and he has been a consultant at foreign institutions such as the Intense Pulsed Neutron Source (IPNS) at Argonne National Laboratory, Illinois. Arriving as he did at a time when large-scale central user facilities were first becoming established, Spencer has played a significant role in shaping the way these facilities operate and produce science. The Current Challenges Workshop was a fitting tribute to his work in disordered materials science and demonstrates how vibrant the field has become as a result.

7 CFR 205.669 - [Reserved

Code of Federal Regulations, 2010 CFR

2010-01-01

..., Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) ORGANIC FOODS PRODUCTION ACT PROVISIONS NATIONAL ORGANIC PROGRAM Administrative Compliance § 205.669 [Reserved] Inspection and Testing...

24 CFR 266.510 - HFA responsibilities.

Code of Federal Regulations, 2010 CFR

2010-04-01

... HOUSING FINANCE AGENCY RISK-SHARING PROGRAM FOR INSURED AFFORDABLE MULTIFAMILY PROJECT LOANS Project Management and Servicing § 266.510 HFA responsibilities. (a) Inspections. The HFA must perform inspections in accordance with the physical inspection procedures in 24 CFR part 5, subpart G. (b) Annual audits of projects...

24 CFR 3286.505 - Minimum elements to be inspected.

Code of Federal Regulations, 2010 CFR

2010-04-01

... with respect to home design and construction; (b) Consideration of site-specific conditions; (c) Site... HOUSING AND URBAN DEVELOPMENT MANUFACTURED HOME INSTALLATION PROGRAM Inspection of Installations in HUD-Administered States § 3286.505 Minimum elements to be inspected. The installation of every manufactured home...

Architectural: Construction, Supervision, and Inspection. Course of Study.

ERIC Educational Resources Information Center

Robson, Frank

This architectural course of study is part of a construction, supervision, and inspection series, which provides instructional materials for community or junior college technical courses in the inspection program. Material covered pertains to: construction contracts, schedules, and site preparation; footings and foundations; masonry and…

Developing a methodology to inspect and assess conditions of short span structures on county roads in Wyoming.

DOT National Transportation Integrated Search

2015-12-01

Ever since the introduction of the National Bridge Inspection Standards (NBIS) in 1971, there has been a : tremendous amount of effort put into bridge rehabilitation programs and safety inspections. The : Wyoming Department of Transportation (WYDOT) ...

42 CFR 493.565 - Selection for validation inspection-laboratory responsibilities.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 5 2010-10-01 2010-10-01 false Selection for validation inspection-laboratory... Program § 493.565 Selection for validation inspection—laboratory responsibilities. A laboratory selected for a validation inspection must do the following: (a) Authorize its accreditation organization or...

Annual Radioactive Waste Tank Inspection Program 1994

DOE Office of Scientific and Technical Information (OSTI.GOV)

McNatt, F.G. Sr.

1995-04-01

Aqueous radioactive wastes from Savannah River Site (SRS) separations processes are contained in large underground carbon steel tanks. Inspections made during 1994 to evaluate these vessels and evaluations based on data accrued by inspections made since the tanks were constructed are the subject of this report.

24 CFR 266.510 - HFA responsibilities.

Code of Federal Regulations, 2014 CFR

2014-04-01

... HOUSING FINANCE AGENCY RISK-SHARING PROGRAM FOR INSURED AFFORDABLE MULTIFAMILY PROJECT LOANS Project Management and Servicing § 266.510 HFA responsibilities. (a) Inspections. The HFA must perform inspections in accordance with the physical inspection procedures in 24 CFR part 5, subpart G. (b) Annual audits of projects...

24 CFR 266.510 - HFA responsibilities.

Code of Federal Regulations, 2011 CFR

2011-04-01

... HOUSING FINANCE AGENCY RISK-SHARING PROGRAM FOR INSURED AFFORDABLE MULTIFAMILY PROJECT LOANS Project Management and Servicing § 266.510 HFA responsibilities. (a) Inspections. The HFA must perform inspections in accordance with the physical inspection procedures in 24 CFR part 5, subpart G. (b) Annual audits of projects...

24 CFR 266.510 - HFA responsibilities.

Code of Federal Regulations, 2012 CFR

2012-04-01

... HOUSING FINANCE AGENCY RISK-SHARING PROGRAM FOR INSURED AFFORDABLE MULTIFAMILY PROJECT LOANS Project Management and Servicing § 266.510 HFA responsibilities. (a) Inspections. The HFA must perform inspections in accordance with the physical inspection procedures in 24 CFR part 5, subpart G. (b) Annual audits of projects...

24 CFR 266.510 - HFA responsibilities.

Code of Federal Regulations, 2013 CFR

2013-04-01

... HOUSING FINANCE AGENCY RISK-SHARING PROGRAM FOR INSURED AFFORDABLE MULTIFAMILY PROJECT LOANS Project Management and Servicing § 266.510 HFA responsibilities. (a) Inspections. The HFA must perform inspections in accordance with the physical inspection procedures in 24 CFR part 5, subpart G. (b) Annual audits of projects...

42 CFR 493.565 - Selection for validation inspection-laboratory responsibilities.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 5 2012-10-01 2012-10-01 false Selection for validation inspection-laboratory... Program § 493.565 Selection for validation inspection—laboratory responsibilities. A laboratory selected for a validation inspection must do the following: (a) Authorize its accreditation organization or...

42 CFR 493.565 - Selection for validation inspection-laboratory responsibilities.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 5 2011-10-01 2011-10-01 false Selection for validation inspection-laboratory... Program § 493.565 Selection for validation inspection—laboratory responsibilities. A laboratory selected for a validation inspection must do the following: (a) Authorize its accreditation organization or...

42 CFR 493.565 - Selection for validation inspection-laboratory responsibilities.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 5 2013-10-01 2013-10-01 false Selection for validation inspection-laboratory... Program § 493.565 Selection for validation inspection—laboratory responsibilities. A laboratory selected for a validation inspection must do the following: (a) Authorize its accreditation organization or...

42 CFR 493.565 - Selection for validation inspection-laboratory responsibilities.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 5 2014-10-01 2014-10-01 false Selection for validation inspection-laboratory... Program § 493.565 Selection for validation inspection—laboratory responsibilities. A laboratory selected for a validation inspection must do the following: (a) Authorize its accreditation organization or...

Automated Eddy Current Inspection on Space Shuttle Hardware

NASA Technical Reports Server (NTRS)

Hartmann, John; Felker, Jeremy

2007-01-01

Over the life time of the Space Shuttle program, metal parts used for the Reusable Solid Rocket Motors (RSRMs) have been nondestructively inspected for cracks and surface breaking discontinuities using magnetic particle (steel) and penetrant methods. Although these inspections adequately screened for critical sized cracks in most regions of the hardware, it became apparent after detection of several sub-critical flaws that the processes were very dependent on operator attentiveness and training. Throughout the 1990's, eddy current inspections were added to areas that had either limited visual access or were more fracture critical. In the late 1990's. a project was initiated to upgrade NDE inspections with the overall objective of improving inspection reliability and control. An automated eddy current inspection system was installed in 2001. A figure shows one of the inspection bays with the robotic axis of the system highlighted. The system was programmed to inspect the various case, nozzle, and igniter metal components that make up an RSRM. both steel and aluminum. For the past few years, the automated inspection system has been a part of the baseline inspection process for steel components. Although the majority of the RSRM metal part inventory ts free of detectable surface flaws, a few small, sub-critical manufacturing defects have been detected with the automated system. This paper will summarize the benefits that have been realized with the current automated eddy current system, as well as the flaws that have been detected.

75 FR 15701 - Georgia Power Company; Notice of Application for Amendment of License and Soliciting Comments...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-30

... Contact: Any questions regarding this notice should be directed to Isis Johnson, Telephone (202) 502-6346, and e-mail: isis[email protected] . j. Deadline for filing comments, motions to intervene, and protest...

Looking to 2050: The USGS Integrated Software for Imagers and Spectrometers (ISIS)

NASA Astrophysics Data System (ADS)

Becker, T. L.; Edmundson, K. L.; Sides, S.; Hare, T. M.; Laura, J. R.

2017-02-01

Astrogeology Science Center develops and maintains software (ISIS) in support of planetary data for a diverse set of missions. We plan to provide support through the future while adapting to changes in hardware, software, and science requirements.

THE NEWEST CHAPTER IN COUNTERINSURGENCY OPERATIONS: DEFEATING THE ISLAMIC STATE OF IRAQ AND THE LEVANT EXPLORING HOW TO SUCCEED IN LIGHT OF RECENT COUNTERINSURGENCY OPERATIONS THAT YIELDED LIMITED OR NO SUCCESS

DTIC Science & Technology

2015-10-01

concerns. Third, insurgent support bases and activities in Pakistan needed be eliminated. In every Afghanistan insurgency since 1979 , insurgents have...Vinograd, “ISIS Attacks Soared in Past 3 Months: HIS Jane’s Database”, web 136. Vinograd, “Are the Airstrike Against ISIS Working?”, web...Attacks Soared in Past 3 Months: IHS Jane’s Database.” NBC News, 21 Oct 2015. Web. 24 Oct 2015. Welna, David. “After A Year of Bombing ISIS

Observing Globular Cluster RR Lyrae Variables with the BYU West Mountain Observatory

NASA Astrophysics Data System (ADS)

Jeffery, E. J.; Joner, M. D.

2016-06-01

We have utilized the 0.9-meter telescope of the Brigham Young University West Mountain Observatory to secure data on six northern hemisphere globular clusters. Here we present representative observations of RR Lyrae stars located in these clusters, including light curves. We compare light curves produced using both DAOPHOT and ISIS software packages. Light curve fitting is done with FITLC. We find that for well-separated stars, DAOPHOT and ISIS provide comparable results. However, for stars within the cluster core, ISIS provides superior results. These improved techniques will allow us to better measure the properties of cluster variable stars.

Effect of duration and inter-stimulus interval on auditory temporal order discrimination in young normal-hearing and elderly hearing-impaired listeners

NASA Astrophysics Data System (ADS)

Narendran, Mini M.; Humes, Larry E.

2003-04-01

Increasing the rate of presentation can have a deleterious effect on auditory processing, especially among the elderly. Rate can be manipulated by changing the duration of individual components of a sequence of sounds, by changing the inter-stimulus interval (ISI) between components, or both. Consequently, when age-related deficits in performance appear to be attributable to rate of stimulus presentation, it is often the case that alternative explanations in terms of the effects of stimulus duration or ISI are also possible. In this study, the independent effects of duration and ISI on the discrimination of temporal order for four-tone sequences were investigated in a group of young normal-hearing and elderly hearing-impaired listeners. It was found that discrimination performance was driven by the rate of presentation, rather than stimulus duration or ISI alone, for both groups of listeners. The performance of the two groups of listeners differed significantly for the fastest presentation rates, but was similar for the slower rates. Slowing the rate of presentation seemed to improve performance, regardless of whether this was done by increasing stimulus duration or increasing ISI, and this was observed for both groups of listeners. [Work supported, in part, by NIA.

40 CFR 160.15 - Inspection of a testing facility.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Inspection of a testing facility. 160.15 Section 160.15 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS GOOD LABORATORY PRACTICE STANDARDS General Provisions § 160.15 Inspection of a testing facility...