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Sample records for instrument voor het

  1. Localization of HET-S to the Cell Periphery, Not to [Het-s] Aggregates, Is Associated with [Het-s]–HET-S Toxicity

    PubMed Central

    Mathur, Vidhu; Seuring, Carolin; Riek, Roland; Saupe, Sven J.

    2012-01-01

    Prion diseases are associated with accumulation of the amyloid form of the prion protein, but the mechanisms of toxicity are unknown. Amyloid toxicity is also associated with fungal prions. In Podospora anserina, the simultaneous presence of [Het-s] prion and its allelic protein HET-S causes cell death in a self-/nonself-discrimination process. Here, using the prion form of a fragment of HET-s ([PrD157+]), we show that [Het-s]–HET-S toxicity can be faithfully recapitulated in yeast. Overexpression of Hsp40 chaperone, Sis1, rescues this toxicity by curing cells of [PrD157+]. We find no evidence for toxic [PrD157+] conformers in the presence of HET-S. Instead, [PrD157+] appears to seed HET-S to accumulate at the cell periphery and to form aggregates distinct from visible [PrD157+] aggregates. Furthermore, HET-S mutants that cause HET-S to be sequestered into [PrD157+] prion aggregates are not toxic. The localization of HET-S at the cell periphery and its association with cell death was also observed in the native host Podospora anserina. Thus, upon interaction with [Het-s], HET-S localizes to the cell periphery, and this relocalization, rather than the formation of mixed HET-s/HET-S aggregates, is associated with toxicity. PMID:22037764

  2. The Mechanism of Prion Inhibition by HET-S

    PubMed Central

    Greenwald, Jason; Buhtz, Carolin; Ritter, Christiane; Kwiatkowski, Witek; Choe, Senyon; Maddelein, Marie-Lise; Ness, Frederique; Cescau, Sandra; Soragni, Alice; Leitz, Dominik; Saupe, Sven J.; Riek, Roland

    2012-01-01

    SUMMARY HET-S (97% identical to HET-s) has an N-terminal globular domain that exerts a prion-inhibitory effect in cis on its own prion-forming domain (PFD) and in trans on HET-s prion propagation. We show that HET-S fails to form fibrils in vitro and that it inhibits HET-s PFD fibrillization in trans. In vivo analyses indicate that β-structuring of the HET-S PFD is required for HET-S activity. The crystal structures of the globular domains of HET-s and HET-S are highly similar, comprising a helical fold, while NMR-based characterizations revealed no differences in the conformations of the PFDs. We conclude that prion inhibition is not encoded by structure but rather in stability and oligomerization properties: when HET-S forms a prion seed or is incorporated into a HET-s fibril via its PFD, the β-structuring in this domain induces a change in its globular domain, generating a molecular species that is incompetent for fibril growth. PMID:20620958

  3. HET Spectroscopy of Extragalactic Novae

    NASA Astrophysics Data System (ADS)

    Shafter, Allen W.; Coelho, E. A.; Misselt, K. A.; Bode, M. F.; Darnley, M. J.

    2006-12-01

    We are currently involved in a multifaceted campaign to study extragalactic novae in the optical and IR using a variety of instruments: The Mount Laguna 1m, the Steward 2.3m, and the Liverpool 2m telescopes for optical imaging, the Hobbey-Eberly Telescope (HET) for optical spectroscopy, and the Spitzer Space Telescope for IR photometry and spectroscopy. Here, we report the initial results from our program of spectroscopic observations obtained with the LRS on the HET. Thus far, we have obtained spectra of three novae: Nova M31-2006#9 (ATEL 887), Nova M32-2006#1 (CBET 591), and Nova M33-2006#1 (CBET 655), which were taken on 24-Sep-2006 UT, 30-Sep-2006 UT, and 02-Oct-2006 UT, approximately 6, 65, and 4 days post discovery, for the three novae respectively. The spectra of Nova M31-2006#9 and Nova M33-2006#1 revealed prominent Balmer (FWHM 1600 km/s) and Fe II emission lines typical of the "Fe II" class in the classification system of Williams (1992 AJ, 104, 725). The spectrum of Nova M32-2006#1, which was obtained much longer after eruption, showed strong H-alpha (FWHM 1300 km/s), along with weaker H-beta, Fe II, and [N II] 5755, indicating that this nova is also a member of the Fe II class, and that it had entered the nebular phase at the time of our observations. In addition to these three novae, we also attempted to obtain a spectrum of Nova M31-2006#7 (CBET 615) on 23-Sep-2006 UT, approximately three weeks after discovery. However, by the time of our observations, the nova had faded to invisibility. An 1800s integration at the reported position reveled no trace of the nova. It is likely that this optical transient was an unusually fast nova, possibly of the "He/N" class. This work is being supported in part by NSF grant AST-0607682.

  4. Mutational analysis of the [Het-s] prion analog of Podospora anserina. A short N-terminal peptide allows prion propagation.

    PubMed Central

    Coustou, V; Deleu, C; Saupe, S J; Bégueret, J

    1999-01-01

    The het-s locus is one of nine known het (heterokaryon incompatibility) loci of the fungus Podospora anserina. This locus exists as two wild-type alleles, het-s and het-S, which encode 289 amino acid proteins differing at 13 amino acid positions. The het-s and het-S alleles are incompatible as their coexpression in the same cytoplasm causes a characteristic cell death reaction. We have proposed that the HET-s protein is a prion analog. Strains of the het-s genotype exist in two phenotypic states, the neutral [Het-s*] and the active [Het-s] phenotype. The [Het-s] phenotype is infectious and is transmitted to [Het-s*] strains through cytoplasmic contact. het-s and het-S were associated in a single haploid nucleus to generate a self-incompatible strain that displays a restricted and abnormal growth. In the present article we report the molecular characterization of a collection of mutants that restore the ability of this self-incompatible strain to grow. We also describe the functional analysis of a series of deletion constructs and site-directed mutants. Together, these analyses define positions critical for reactivity and allele specificity. We show that a 112-amino-acid-long N-terminal peptide of HET-s retains [Het-s] activity. Moreover, expression of a mutant het-s allele truncated at position 26 is sufficient to allow propagation of the [Het-s] prion analog. PMID:10581272

  5. Op weg naar een didactiek voor natuurkunde-experimenten op afstand : Ontwerp en evaluatie van een via internet uitvoerbaar experiment voor leerlingen uit het voortgezet onderwijs

    NASA Astrophysics Data System (ADS)

    Engelbarts, M. B. A.

    2009-02-01

    The subject of this thesis is a developmental study on “remote experimenting” in education. It concerns the development of a remote experiment that enables pre-university students to carry out a physics experiment at a distance via the internet. Remote experiments can offer several (practical) benefits when compared to conventional experiments but the desire to exploit these benefits put special demands on the design of the experiment, since the students might be conducting the experiment without a teacher in the vicinity. As a consequence of these demands it was decided to focus on exploring the possibilities and problems of remote experiments conducted in the absence of a teacher. The research was carried out in two cycles and focused on the development of a remote experiment that could be conducted autonomously by pre-university students to measure the speed of light in several media. This should answer the global question: What should a technically, as well as didactically, well-functioning remote experiment look like? The first cycle had an explorative character. It showed that technically the experiment already functioned quite well. However, many problems were observed concerning the content, and the way the students were tackling it. This led to two categories of recommendations. Concerning the content, the material should aim at making the students more aware of what they are doing and why they are doing it and several content related problems needed to be avoided. The second category of recommendations concerned the format of the material: the design and the working method. Special attention should be paid to designing a clear structure for the website and adding interaction and control, (feedback- and reflection facilities) to activate the students and guide them through the material. In the second research cycle these recommendations were followed by designing the material within the theoretical framework of the problem posing theory. A didactical structure was designed before writing the actual lesson material for the website describing the inter-related conceptual and content-related motivational pathway of the intended teaching-learning process. The lesson material was set up in such a way that the students are repeatedly confronted with a practical problem to solve and they play an active role in developing the method of measurement. Secondly, in an attempt to compensate for the absence of the teacher and support the teaching-learning process some format elements were developed and deployed like an automated question-, and feedback system that supported the students, activated them and gave them insight into their learning process and a ‘Where-am-I’-window that showed their current position within the material. This all had led to a technically as well as didactically well functioning remote experiment in which, at a global level, the line of reasoning was made explicit and recognizable for the students, and ad a local level was build up out of well connected successive activities and required the students to adopt an active attitude.

  6. As a toxin dies a prion comes to life: A tentative natural history of the [Het-s] prion.

    PubMed

    Daskalov, Asen; Saupe, Sven J

    2015-01-01

    A variety of signaling pathways, in particular with roles in cell fate and host defense, operate by a prion-like mechanism consisting in the formation of open-ended oligomeric signaling complexes termed signalosomes. This mechanism emerges as a novel paradigm in signal transduction. Among the proteins forming such signaling complexes are the Nod-like receptors (NLR), involved in innate immunity. It now appears that the [Het-s] fungal prion derives from such a cell-fate defining signaling system controlled by a fungal NLR. What was once considered as an isolated oddity turns out to be related to a conserved and widespread signaling mechanism. Herein, we recall the relation of the [Het-s] prion to the signal transduction pathway controlled by the NWD2 Nod-like receptor, leading to activation of the HET-S pore-forming cell death execution protein. We explicit an evolutionary scenario in which formation of the [Het-s] prion is the result of an exaptation process or how a loss-of-function mutation in a pore-forming cell death execution protein (HET-S) has given birth to a functional prion ([Het-s]).

  7. Hobby-Eberly Telescope: instrumentation and current performance

    NASA Astrophysics Data System (ADS)

    Hill, Gary J.

    2000-08-01

    The Hobby-Eberly Telescope (HET) is a revolutionary large telescope of 9.2 meter aperture, located in West Texas at McDonald Observatory. HET has been constructed by a consortium of US and German universities for about 16 million dollars. First light was obtained on December 11, 1996, HET was dedicate don October 8, 1997, and early scientific operations started on October 8, 1999. The HET operates with a fixed segmented primary and has a tracker which moves the four-mirror corrector and prime focus instrument package to track the sidereal and non-sidereal motions of objects. Here we describe the current performance of the HET relative to its goals.

  8. Hetdex: Virus Instrument

    NASA Astrophysics Data System (ADS)

    Lee, Hanshin; Hill, G. J.; DePoy, D. L.; Tuttle, S.; Marshall, J. L.; Vattiat, B. L.; Prochaska, T.; Chonis, T. S.; Allen, R.; HETDEX Collaboration

    2012-01-01

    The Visible Integral-field-unit Replicable Unit Spectrograph (VIRUS) instrument is made up of 150+ individually compact and identical spectrographs, each fed by a fiber integral-field unit. The instrument provides integral field spectroscopy at wavelengths between 350nm and 550nm of over 33,600 spatial elements per observation, each 1.8 sq. arcsec on the sky, at R 700. The instrument will be fed by a new wide-field corrector (WFC) of the Hobby-Eberly Telescope (HET) with increased science field of view as large as 22arcmin diameter and telescope aperture of 10m. This will enable the HETDEX, a large area blind survey of Lyman-alpha emitting galaxies at redshift z < 3.5. The status of VIRUS instrument construction is summarized.

  9. HET Spectra of Three Recent Extragalactic Novae

    NASA Astrophysics Data System (ADS)

    Shafter, A. W.; Coelho, E. A.; Misselt, K. A.; Bode, M. F.; Darnley, M. J.; Quimby, R.

    2006-10-01

    We report optical spectroscopic observations (4280Å - 7280Å) obtained with the HET of three extragalactic novae: Nova M31 2006 No. 9 (ATEL #887), Nova M32 2006 No. 1 (CBET #591), and Nova M33 2006 No. 1 (CBET #655). The spectra were obtained on 24 Sep 2006 UT, 30 Sep 2006 UT, and 02 Oct 2006 UT, corresponding to approximately 6, 65, and 4 days post discovery, for the three novae respectively.

  10. Present and future instrumentation for the Hobby-Eberly Telescope

    NASA Astrophysics Data System (ADS)

    Hill, Gary J.; MacQueen, Phillip J.; Palunas, Povilas; Shetrone, Matthew D.; Booth, John A.

    2006-06-01

    The Hobby-Eberly Telescope (HET) is an innovative large telescope of 9.2 meter aperture, located in West Texas at McDonald Observatory. The HET operates with a fixed segmented primary and has a tracker which moves the four-mirror corrector and prime focus instrument package to track the sidereal and non-sidereal motions of objects. The HET has been taking science data for six years. Work over the past two years has improved performance significantly, replacing the mirror coatings and installing metrology equipment to provide feedback that aids tracking and alignment of the primary mirror segments. The first phase of HET instrumentation includes three facility instruments: the Low Resolution Spectrograph (LRS), the Medium Resolution Spectrograph (MRS), and High Resolution Spectrograph (HRS). The current status of these instruments is described. A major upgrade of HET is planned that will increase the field of view to 22 arcminutes diameter, replacing the corrector, tracker and prime focus instrument package. This wide field upgrade will feed a revolutionary new integral field spectrograph called VIRUS, in support of the Hobby-Eberly Telescope Dark Energy Experiment (HETDEX).

  11. Performance of the Hobby-Eberly Telescope and facility instruments

    NASA Astrophysics Data System (ADS)

    Hill, Gary J.; MacQueen, Phillip J.; Ramsey, Lawrence W.; Shetrone, Matthew D.

    2004-09-01

    The Hobby-Eberly Telescope (HET) is a revolutionary large telescope of 9.2 meter aperture, located in West Texas at McDonald Observatory. The HET operates with a fixed segmented primary and has a tracker which moves the four-mirror corrector and prime focus instrument package to track the sidereal and non-sidereal motions of objects. The HET has been taking science data for five years, but the image quality and primary mirror stability have been far from specifications. Work over the past two years has improved performance significantly, and demonstrated site-seeing limited images of 0.8 arcsec., showing that the telescope will meet all specifications. The performance of the HET is discussed in detail. The first phase of HET instrumentation includes three facility instruments: the Low Resolution Spectrograph (LRS), the Medium Resolution Spectrograph (MRS), and High Resolution Spectrograph (HRS). The current status of the instruments is described. Upcoming near infrared capabilities for the LRS and MRS are also discussed.

  12. Present and future instrumentation for the Hobby-Eberly Telescope

    NASA Astrophysics Data System (ADS)

    Hill, Gary J.; MacQueen, Phillip J.; Palunas, Povilas; Barnes, Stuart I.; Shetrone, Matthew D.

    2008-07-01

    The Hobby-Eberly Telescope (HET) is an innovative large telescope of 9.2 meter aperture, located in West Texas at McDonald Observatory. The HET operates with a fixed segmented primary and has a tracker which moves the four-mirror corrector and prime focus instrument package to track the sidereal and non-sidereal motions of objects. The HET has been taking science data for nearly a decade. Recent work has improved performance significantly, replacing the mirror coatings and installing metrology equipment to provide feedback that aids tracking and alignment of the primary mirror segments. The first phase of HET instrumentation included three facility instruments: the Low Resolution Spectrograph (LRS), the Medium Resolution Spectrograph (MRS), and High Resolution Spectrograph (HRS). The current status of these instruments is briefly described. A major upgrade of HET is in progress that will increase the field of view to 22 arcminutes diameter, replacing the corrector, tracker and prime focus instrument package. This wide field upgrade will feed a revolutionary new integral field spectrograph called VIRUS, in support of the Hobby-Eberly Telescope Dark Energy Experiment (HETDEX). VIRUS is a facility instrument that consists of 150 or more copies of a simple unit integral field spectrograph. In total VIRUS will observe 34,000 spatial elements simultaneously, and will open up wide-area surveys of the emission-line universe for the first time. We describe the HET wide field upgrade and the development of VIRUS, including results from testing the prototype of the VIRUS unit spectrograph.

  13. [Disclosure of conflicts of interest in the Tijdschrift voor Psychiatrie].

    PubMed

    Bergoets, M; Pieters, G

    2009-01-01

    Between March 2000 and December 2008 authors disclosed conflicts of interest in 9% of articles in the Tijdschrift voor Psychiatrie. For the same period, in the articles dealing with pharmaceuticals, the percentage of articles containing disclosures of conflict of interest was considerably higher, namely 24%. The policy of the journal with regard to the disclosure of conflicts of interest has helped to promote transparency. Further efforts are needed to encourage authors to disclose conflicts of interest.

  14. Performance of the facility instruments on the Hobby-Eberly telescope

    NASA Astrophysics Data System (ADS)

    Hill, Gary J.; MacQueen, Phillip J.; Ramsey, Lawrence W.

    2003-03-01

    The Hobby-Eberly Telescope (HET) is a revolutionary large telescope of 9.2 meter aperture, located in West Texas at McDonald Observatory. Early scientific operations started on October 8, 1999. The HET operates with a fixed segmented primary and has a tracker which moves the four-mirror corrector and prime focus instrument package to track the sidereal and non-sidereal motions of objects. As of two years ago, the HET was taking science data but the image quality and primary mirror stability were far from specifications. We established the HET Completion Project to identify and fix these problems, and here we describe the current performance of the HET relative to its goals, focusing on progress made in the past two years. The first phase of HET instrumentation includes three facility instruments: the Low Resolution Spectrograph (LRS) and High Resolution Spectrograph (HRS), which are in operation, and the Medium Resolution Spectrograph (MRS), which will be commissioned in the summer and autumn. The current status of the instruments is described in detail with performance measures.

  15. Contribution of Specific Residues of the β-Solenoid Fold to HET-s Prion Function, Amyloid Structure and Stability

    PubMed Central

    Schmidlin, Thierry; Chi, Celestine N.; Wasmer, Christian; Schütz, Anne; Ceschin, Johanna; Clavé, Corinne; Cescau, Sandra; Meier, Beat; Riek, Roland; Saupe, Sven J.

    2014-01-01

    The [Het-s] prion of the fungus Podospora anserina represents a good model system for studying the structure-function relationship in amyloid proteins because a high resolution solid-state NMR structure of the amyloid prion form of the HET-s prion forming domain (PFD) is available. The HET-s PFD adopts a specific β-solenoid fold with two rungs of β-strands delimiting a triangular hydrophobic core. A C-terminal loop folds back onto the rigid core region and forms a more dynamic semi-hydrophobic pocket extending the hydrophobic core. Herein, an alanine scanning mutagenesis of the HET-s PFD was conducted. Different structural elements identified in the prion fold such as the triangular hydrophobic core, the salt bridges, the asparagines ladders and the C-terminal loop were altered and the effect of these mutations on prion function, fibril structure and stability was assayed. Prion activity and structure were found to be very robust; only a few key mutations were able to corrupt structure and function. While some mutations strongly destabilize the fold, many substitutions in fact increase stability of the fold. This increase in structural stability did not influence prion formation propensity in vivo. However, if an Ala replacement did alter the structure of the core or did influence the shape of the denaturation curve, the corresponding variant showed a decreased prion efficacy. It is also the finding that in addition to the structural elements of the rigid core region, the aromatic residues in the C-terminal semi-hydrophobic pocket are critical for prion propagation. Mutations in the latter region either positively or negatively affected prion formation. We thus identify a region that modulates prion formation although it is not part of the rigid cross-β core, an observation that might be relevant to other amyloid models. PMID:24945274

  16. HET-E and HET-D belong to a new subfamily of WD40 proteins involved in vegetative incompatibility specificity in the fungus Podospora anserina.

    PubMed Central

    Espagne, Eric; Balhadère, Pascale; Penin, Marie-Louise; Barreau, Christian; Turcq, Béatrice

    2002-01-01

    Vegetative incompatibility, which is very common in filamentous fungi, prevents a viable heterokaryotic cell from being formed by the fusion of filaments from two different wild-type strains. Such incompatibility is always the consequence of at least one genetic difference in specific genes (het genes). In Podospora anserina, alleles of the het-e and het-d loci control heterokaryon viability through genetic interactions with alleles of the unlinked het-c locus. The het-d2(Y) gene was isolated and shown to have strong similarity with the previously described het-e1(A) gene. Like the HET-E protein, the HET-D putative protein displayed a GTP-binding domain and seemed to require a minimal number of 11 WD40 repeats to be active in incompatibility. Apart from incompatibility specificity, no other function could be identified by disrupting the het-d gene. Sequence comparison of different het-e alleles suggested that het-e specificity is determined by the sequence of the WD40 repeat domain. In particular, the amino acids present on the upper face of the predicted beta-propeller structure defined by this domain may confer the incompatible interaction specificity. PMID:12019224

  17. Design, testing, and performance of the Hobby Eberly Telescope prime focus instrument package

    NASA Astrophysics Data System (ADS)

    Vattiat, Brian; Hill, Gary J.; Lee, Hanshin; Perry, Dave M.; Rafal, Marc D.; Rafferty, Tom; Savage, Richard; Taylor, Charles A.; Moreira, Walter; Smith, Michael

    2012-09-01

    The Hobby-Eberly Telescope (HET) is undergoing an upgrade to increase the field of view to 22 arc-minutes with the dark energy survey HETDEX the initial science goal [1]. Here we report on the engineering development of a suite of instruments located at prime focus of the upgraded HET. The Prime Focus Instrument Package (PFIP) contains acquisition, guiding, and wave front sensing instrumentation [2], the fiber feeds for the facility spectrographs (VIRUS, HRS, MRS, LRS2), and ancillary hardware. This paper reviews the design and functions of the PFIP and presents details of the mechanical design, integration and testing.

  18. Performance verification testing for HET wide-field upgrade tracker in the laboratory

    NASA Astrophysics Data System (ADS)

    Good, John; Hayes, Richard; Beno, Joseph; Booth, John; Cornell, Mark E.; Hill, Gary J.; Lee, Hanshin; Mock, Jason; Rafal, Marc; Savage, Richard; Soukup, Ian

    2010-07-01

    To enable the Hobby-Eberly Telescope Dark Energy Experiment (HETDEX), the McDonald Observatory (MDO) and the Center for Electro-mechanics (CEM) at the University of Texas at Austin are developing a new HET tracker in support of the Wide-Field Upgrade (WFU) and the Visible Integral-Field Replicable Unit Spectrograph (VIRUS). The precision tracker is required to maintain the position of a 3,100 kg payload within ten microns of its desired position relative to the telescope's primary mirror. The hardware system to accomplish this has ten precision controlled actuators. Prior to installation on the telescope, full performance verification is required of the completed tracker in CEM's lab, without a primary mirror or the telescope's final instrument package. This requires the development of a laboratory test stand capable of supporting the completed tracker over its full range of motion, as well as means of measurement and methodology that can verify the accuracy of the tracker motion over full travel (4m diameter circle, 400 mm deep, with 9 degrees of tip and tilt) at a cost and schedule in keeping with the HET WFU requirements. Several techniques have been evaluated to complete this series of tests including: photogrammetry, laser tracker, autocollimator, and a distance measuring interferometer, with the laser tracker ultimately being identified as the most viable method. The design of the proposed system and its implementation in the lab is presented along with the test processes, predicted accuracy, and the basis for using the chosen method*.

  19. Vegetative incompatibility in the het-6 region of Neurospora crassa is mediated by two linked genes.

    PubMed Central

    Smith, M L; Micali, O C; Hubbard, S P; Mir-Rashed, N; Jacobson, D J; Glass, N L

    2000-01-01

    Non-self-recognition during asexual growth of Neurospora crassa involves restriction of heterokaryon formation via genetic differences at 11 het loci, including mating type. The het-6 locus maps to a 250-kbp region of LGIIL. We used restriction fragment length polymorphisms in progeny with crossovers in the het-6 region and a DNA transformation assay to identify two genes in a 25-kbp region that have vegetative incompatibility activity. The predicted product of one of these genes, which we designate het-6(OR), has three regions of amino acid sequence similarity to the predicted product of the het-e vegetative incompatibility gene in Podospora anserina and to the predicted product of tol, which mediates mating-type vegetative incompatibility in N. crassa. The predicted product of the alternative het-6 allele, HET-6(PA), shares only 68% amino acid identity with HET-6(OR). The second incompatibility gene, un-24(OR), encodes the large subunit of ribonucleotide reductase, which is essential for de novo synthesis of DNA. A region in the carboxyl-terminal portion of UN-24 is associated with incompatibility and is variable between un-24(OR) and the alternative allele un-24(PA). Linkage analysis indicates that the 25-kbp un-24-het-6 region is inherited as a block, suggesting that a nonallelic interaction may occur between un-24 and het-6 and possibly other loci within this region to mediate vegetative incompatibility in the het-6 region of N. crassa. PMID:10880472

  20. The HET-S/s Prion Motif in the Control of Programmed Cell Death.

    PubMed

    Riek, Roland; Saupe, Sven J

    2016-01-01

    The [Het-s] prion of the fungus Podospora anserina is a well-studied model system to elucidate the action of prions and beyond. The [Het-s] prion works as an activation trigger of a cell death execution protein termed HET-S. Amyloid transconformation of the prion-forming region of HET-S induces activation of its pore-forming cell death execution HeLo domain. The prion motif functions in a signal transduction process by which a nucleotide-binding oligomerization domain (NOD)-like receptor termed NWD2 controls the HET-S cell death effector. This prion motif thus corresponds to a functional amyloid motif, allowing a conformational crosstalk between homologous motif domains in signal transduction processes that appears to be widespread from the fungal to the mammalian animal kingdoms. This review aims to establish a structure-activity relationship of the HET-S/s prion system and sets it in the context of its wider biological significance. PMID:27352624

  1. Fungal prion HET-s as a model for structural complexity and self-propagation in prions.

    PubMed

    Wan, William; Stubbs, Gerald

    2014-04-01

    The highly ordered and reproducible structure of the fungal prion HET-s makes it an excellent model system for studying the inherent properties of prions, self-propagating infectious proteins that have been implicated in a number of fatal diseases. In particular, the HET-s prion-forming domain readily folds into a relatively complex two-rung β-solenoid amyloid. The faithful self-propagation of this fold involves a diverse array of inter- and intramolecular structural features. These features include a long flexible loop connecting the two rungs, buried polar residues, salt bridges, and asparagine ladders. We have used site-directed mutagenesis and X-ray fiber diffraction to probe the relative importance of these features for the formation of β-solenoid structure, as well as the cumulative effects of multiple mutations. Using fibrillization kinetics and chemical stability assays, we have determined the biophysical effects of our mutations on the assembly and stability of the prion-forming domain. We have found that a diversity of structural features provides a level of redundancy that allows robust folding and stability even in the face of significant sequence alterations and suboptimal environmental conditions. Our findings provide fundamental insights into the structural interactions necessary for self-propagation. Propagation of prion structure seems to require an obligatory level of complexity that may not be reproducible in short peptide models.

  2. Aeronautic instruments

    NASA Technical Reports Server (NTRS)

    Everling, E; Koppe, H

    1924-01-01

    The development of aeronautic instruments. Vibrations, rapid changes of the conditions of flight and of atmospheric conditions, influence of the air stream all call for particular design and construction of the individual instruments. This is shown by certain examples of individual instruments and of various classes of instruments for measuring pressure, change of altitude, temperature, velocity, inclination and turning or combinations of these.

  3. The proposed high-energy telescope (HET) for EXIST

    NASA Astrophysics Data System (ADS)

    Hong, J.; Grindlay, J.; Allen, B.; Skinner, G.; Barthelmy, S.; Gehrels, N.; Garson, A.; Krawczynski, H.; Cook, W.; Harrison, F.; Natalucci, L.; Ubertini, P.

    2010-07-01

    The hard X-ray sky now being studied by INTEGRAL and Swift and soon by NuSTAR is rich with energetic phenomena and highly variable non-thermal phenomena on a broad range of timescales. The High Energy Telescope (HET) on the proposed Energetic X-ray Imaging Survey Telescope (EXIST) mission will repeatedly survey the full sky for rare and luminous hard X-ray phenomena at unprecedented sensitivities. It will detect and localize (<20", at 5σ threshold) X-ray sources quickly for immediate followup identification by two other onboard telescopes - the Soft X-ray imager (SXI) and Optical/Infrared Telescope (IRT). The large array (4.5 m2) of imaging (0.6 mm pixel) CZT detectors in the HET, a coded-aperture telescope, will provide unprecedented high sensitivity (~0.06 mCrab Full Sky in a 2 year continuous scanning survey) in the 5 - 600 keV band. The large field of view (90° × 70°) and zenith scanning with alternating-orbital nodding motion planned for the first 2 years of the mission will enable nearly continuous monitoring of the full sky. A 3y followup pointed mission phase provides deep UV-Optical-IR-Soft X-ray and Hard X-ray imaging and spectroscopy for thousands of sources discovered in the Survey. We review the HET design concept and report the recent progress of the CZT detector development, which is underway through a series of balloon-borne wide-field hard X-ray telescope experiments, ProtoEXIST. We carried out a successful flight of the first generation of fine pixel large area CZT detectors (ProtoEXIST1) on Oct 9, 2009. We also summarize our future plan (ProtoEXIST2 & 3) for the technology development needed for the HET.

  4. Gyroscopic Instruments for Instrument Flying

    NASA Technical Reports Server (NTRS)

    Brombacher, W G; Trent, W C

    1938-01-01

    The gyroscopic instruments commonly used in instrument flying in the United States are the turn indicator, the directional gyro, the gyromagnetic compass, the gyroscopic horizon, and the automatic pilot. These instruments are described. Performance data and the method of testing in the laboratory are given for the turn indicator, the directional gyro, and the gyroscopic horizon. Apparatus for driving the instruments is discussed.

  5. A Yeast Toxic Mutant of HET-s(218-289) Prion Displays Alternative Intermediates of Amyloidogenesis

    PubMed Central

    Berthelot, Karine; Lecomte, Sophie; Géan, Julie; Immel, Françoise; Cullin, Christophe

    2010-01-01

    Amyloids are thought to be involved in various types of neurodegenerative disorders. Several kinds of intermediates, differing in morphology, size, and toxicity, have been identified in the multistep amyloidogenesis process. However, the mechanisms explaining amyloid toxicity remain unclear. We previously generated a toxic mutant of the nontoxic HET-s(218-289) amyloid in yeast. Here we report that toxic and nontoxic amyloids differ not only in their structures but also in their assembling process. We used multiple and complementary methods to investigate the intermediates formed by these two amyloids. With the methods used, no intermediates were observed for the nontoxic amyloid; however, under the same experimental conditions, the toxic mutant displayed visible oligomeric and fibrillar intermediates. PMID:20713008

  6. 40 CFR 721.4100 - Tris(disubstituted alkyl) het-er-o-cy-cle.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 31 2014-07-01 2014-07-01 false Tris(disubstituted alkyl) het-er-o-cy... Specific Chemical Substances § 721.4100 Tris(disubstituted alkyl) het-er-o-cy-cle. (a) Chemical substance... tris(disubstituted alkyl) heterocycle (P-90-142) is subject to reporting under this section for...

  7. 40 CFR 721.4100 - Tris(disubstituted alkyl) het-er-o-cy-cle.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 31 2011-07-01 2011-07-01 false Tris(disubstituted alkyl) het-er-o-cy... Specific Chemical Substances § 721.4100 Tris(disubstituted alkyl) het-er-o-cy-cle. (a) Chemical substance... tris(disubstituted alkyl) heterocycle (P-90-142) is subject to reporting under this section for...

  8. 40 CFR 721.4100 - Tris(disubstituted alkyl) het-er-o-cy-cle.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 32 2012-07-01 2012-07-01 false Tris(disubstituted alkyl) het-er-o-cy... Specific Chemical Substances § 721.4100 Tris(disubstituted alkyl) het-er-o-cy-cle. (a) Chemical substance... tris(disubstituted alkyl) heterocycle (P-90-142) is subject to reporting under this section for...

  9. 40 CFR 721.4100 - Tris(disubstituted alkyl) het-er-o-cy-cle.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 32 2013-07-01 2013-07-01 false Tris(disubstituted alkyl) het-er-o-cy... Specific Chemical Substances § 721.4100 Tris(disubstituted alkyl) het-er-o-cy-cle. (a) Chemical substance... tris(disubstituted alkyl) heterocycle (P-90-142) is subject to reporting under this section for...

  10. 40 CFR 721.4100 - Tris(disubstituted alkyl) het-er-o-cy-cle.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Tris(disubstituted alkyl) het-er-o-cy... Specific Chemical Substances § 721.4100 Tris(disubstituted alkyl) het-er-o-cy-cle. (a) Chemical substance... tris(disubstituted alkyl) heterocycle (P-90-142) is subject to reporting under this section for...

  11. LRS2: A New Integral Field Spectrograph for the HET

    NASA Astrophysics Data System (ADS)

    Tuttle, Sarah E.; Hill, Gary J.; Chonis, Taylor S.; Tonnesen, Stephanie

    2016-01-01

    Here we present LRS2 (Low Resolution Spectrograph) and highlight early science opportunities with the newly upgraded Hobby Eberly telescope (HET). LRS2 is a four-channel optical wavelength (370nm - 1micron) spectrograph based on two VIRUS unit spectrographs. This fiber-fed integral field spectrograph covers a 12" x 6" field of view, switched between the two units (one blue, and one red) at R~2000. We highlight design elements, including the fundamental modification to grisms (from VPH gratings in VIRUS) to access the higher resolution. We discuss early science opportunities, including investigating nearby "blue-bulge" spiral galaxies and their anomalous star formation distribution.

  12. Fiber Diffraction of the Prion-Forming Domain HET-s(218-289) Shows Dehydration-Induced Deformation of a Complex Amyloid Structure

    SciTech Connect

    Wan, William; Stubbs, Gerald

    2014-05-01

    Amyloids are filamentous protein aggregates that can be formed by many different proteins and are associated with both disease and biological functions. The pathogenicities or biological functions of amyloids are determined by their particular molecular structures, making accurate structural models a requirement for understanding their biological effects. One potential factor that can affect amyloid structures is hydration. Previous studies of simple stacked β-sheet amyloids have suggested that dehydration does not impact structure, but other studies indicated dehydration-related structural changes of a putative water-filled nanotube. Our results show that dehydration significantly affects the molecular structure of the fungal prion-forming domain HET-s(218–289), which forms a β-solenoid with no internal solvent-accessible regions. The dehydration-related structural deformation of HET-s(218–289) indicates that water can play a significant role in complex amyloid structures, even when no obvious water-accessible cavities are present.

  13. The history of the Nederlandse Vereniging voor Hypnose (Netherlands Society of Hypnosis).

    PubMed

    Korsen, A; Wilken, T

    2001-07-01

    The foundation and history of the Nederlandse Vereniging voor Hypnose (Netherlands Society of Hypnosis or Nvvh) is described. The year 2001 marks the 70th anniversary of the Nvvh's creation. The article describes the accomplishments, leadership, and philosophy of the Society across the decades. Current professional and training directions are discussed.

  14. Mass analysis by scanning transmission electron microscopy and electron diffraction validate predictions of stacked beta-solenoid model of HET-s prion fibrils.

    PubMed

    Sen, Anindito; Baxa, Ulrich; Simon, Martha N; Wall, Joseph S; Sabate, Raimon; Saupe, Sven J; Steven, Alasdair C

    2007-02-23

    Fungal prions are infectious filamentous polymers of proteins that are soluble in uninfected cells. In its prion form, the HET-s protein of Podospora anserina participates in a fungal self/non-self recognition phenomenon called heterokaryon incompatibility. Like other prion proteins, HET-s has a so-called "prion domain" (its C-terminal region, HET-s-(218-289)) that is responsible for induction and propagation of the prion in vivo and for fibril formation in vitro. Prion fibrils are thought to have amyloid backbones of polymerized prion domains. A relatively detailed model has been proposed for prion domain fibrils of HET-s based on a variety of experimental constraints (Ritter, C., Maddelein, M. L., Siemer, A. B., Luhrs, T., Ernst, M., Meier, B. H., Saupe, S. J., and Riek, R. (2005) Nature 435, 844-848). To test specific predictions of this model, which envisages axial stacking of beta-solenoids with two coils per subunit, we examined fibrils by electron microscopy. Electron diffraction gave a prominent meridional reflection at (0.47 nm)(-1), indicative of cross-beta structure, as predicted. STEM (scanning transmission electron microscopy) mass-per-unit-length measurements yielded 1.02 +/- 0.16 subunits per 0.94 nm, in agreement with the model prediction (1 subunit per 0.94 nm). This is half the packing density of approximately 1 subunit per 0.47 nm previously obtained for fibrils of the yeast prion proteins, Ure2p and Sup35p, whence it follows that the respective amyloid architectures are basically different.

  15. Structure of transcription factor HetR required for heterocyst differentiation in cyanobacteria.

    SciTech Connect

    Kim, Y.; Joachimiak, G.; Ye, Z.; Binkowski, T; Zhang, R.; Gornicki, P.; Callahan, S.; Hess, W.; Haselkorn, R.; Joachimiak, A.

    2011-06-21

    HetR is an essential regulator of heterocyst development in cyanobacteria. HetR binds to a DNA palindrome upstream of the hetP gene. We report the crystal structure of HetR from Fischerella at 3.0 {angstrom}. The protein is a dimer comprised of a central DNA-binding unit containing the N-terminal regions of the two subunits organized with two helix-turn-helix motifs; two globular flaps extending in opposite directions; and a hood over the central core formed from the C-terminal subdomains. The flaps and hood have no structural precedent in the protein database, therefore representing new folds. The structural assignments are supported by site-directed mutagenesis and DNA-binding studies. We suggest that HetR serves as a scaffold for assembly of transcription components critical for heterocyst development.

  16. Heterogeneous Seeding of a Prion Structure by a Generic Amyloid Form of the Fungal Prion-forming Domain HET-s(218-289)

    SciTech Connect

    Wan, William; Bian, Wen; McDonald, Michele; Kijac, Aleksandra; Wemmer, David E.; Stubbs, Gerald

    2013-11-13

    The fungal prion-forming domain HET-s(218–289) forms infectious amyloid fibrils at physiological pH that were shown by solid-state NMR to be assemblies of a two-rung β-solenoid structure. Under acidic conditions, HET-s(218–289) has been shown to form amyloid fibrils that have very low infectivity in vivo, but structural information about these fibrils has been very limited. We show by x-ray fiber diffraction that the HET-s(218–289) fibrils formed under acidic conditions have a stacked β-sheet architecture commonly found in short amyloidogenic peptides and denatured protein aggregates. At physiological pH, stacked β-sheet fibrils nucleate the formation of the infectious β-solenoid prions in a process of heterogeneous seeding, but do so with kinetic profiles distinct from those of spontaneous or homogeneous (seeded with infectious β-solenoid fibrils) fibrillization. Several serial passages of stacked β-sheet-seeded solutions lead to fibrillization kinetics similar to homogeneously seeded solutions. Our results directly show that structural mutation can occur between substantially different amyloid architectures, lending credence to the suggestion that the processes of strain adaptation and crossing species barriers are facilitated by structural mutation.

  17. Cordless Instruments

    NASA Technical Reports Server (NTRS)

    1981-01-01

    Black & Decker's new cordless lightweight battery powered precision instruments, adapted from NASA's Apollo Lunar Landing program, have been designed to give surgeons optimum freedom and versatility in the operating room. Orthopedic instrument line includes a drill, a driver/reamer and a sagittal saw. All provide up to 20 minutes on a single charge. Power pack is the instrument's handle which is removable for recharging. Microprocessor controlled recharging unit can recharge two power packs together in 30 minutes. Instruments can be gas sterilized, steam-sterilized in an autoclave or immersed for easy cleaning.

  18. SURVEY INSTRUMENT

    DOEpatents

    Borkowski, C J

    1954-01-19

    This pulse-type survey instrument is suitable for readily detecting {alpha} particles in the presence of high {beta} and {gamma} backgrounds. The instruments may also be used to survey for neutrons, {beta} particles and {gamma} rays by employing suitably designed interchangeable probes and selecting an operating potential to correspond to the particular probe.

  19. Expanding the direct HetR regulon in Anabaena sp. strain PCC 7120.

    PubMed

    Videau, Patrick; Ni, Shuisong; Rivers, Orion S; Ushijima, Blake; Feldmann, Erik A; Cozy, Loralyn M; Kennedy, Michael A; Callahan, Sean M

    2014-03-01

    In response to a lack of environmental combined nitrogen, the filamentous cyanobacterium Anabaena sp. strain PCC 7120 differentiates nitrogen-fixing heterocyst cells in a periodic pattern. HetR is a transcription factor that coordinates the regulation of this developmental program. An inverted repeat-containing sequence in the hepA promoter required for proheterocyst-specific transcription was identified based on sequence similarity to a previously characterized binding site for HetR in the promoter of hetP. The binding affinity of HetR for the hepA site is roughly an order of magnitude lower than that for the hetP binding site. A BLAST search of the Anabaena genome identified 166 hepA-like sites that occur as single or tandem sites (two binding sites separated by 13 bp). The vast majority of these sites are present in predicted intergenic regions. HetR bound five representative single binding sites in vitro, and binding was abrogated by transversions in the binding sites that conserved the inverted repeat nature of the sites. Binding to four representative tandem sites was not observed. Transcriptional fusions of the green fluorescent protein gene gfp with putative promoter regions associated with the representative binding sites indicated that HetR could function as either an activator or repressor and that activation was cell-type specific. Taken together, we have expanded the direct HetR regulon and propose a model in which three categories of HetR binding sites, based on binding affinity and nucleotide sequence, contribute to three of the four phases of differentiation.

  20. Expanding the direct HetR regulon in Anabaena sp. strain PCC 7120.

    PubMed

    Videau, Patrick; Ni, Shuisong; Rivers, Orion S; Ushijima, Blake; Feldmann, Erik A; Cozy, Loralyn M; Kennedy, Michael A; Callahan, Sean M

    2014-03-01

    In response to a lack of environmental combined nitrogen, the filamentous cyanobacterium Anabaena sp. strain PCC 7120 differentiates nitrogen-fixing heterocyst cells in a periodic pattern. HetR is a transcription factor that coordinates the regulation of this developmental program. An inverted repeat-containing sequence in the hepA promoter required for proheterocyst-specific transcription was identified based on sequence similarity to a previously characterized binding site for HetR in the promoter of hetP. The binding affinity of HetR for the hepA site is roughly an order of magnitude lower than that for the hetP binding site. A BLAST search of the Anabaena genome identified 166 hepA-like sites that occur as single or tandem sites (two binding sites separated by 13 bp). The vast majority of these sites are present in predicted intergenic regions. HetR bound five representative single binding sites in vitro, and binding was abrogated by transversions in the binding sites that conserved the inverted repeat nature of the sites. Binding to four representative tandem sites was not observed. Transcriptional fusions of the green fluorescent protein gene gfp with putative promoter regions associated with the representative binding sites indicated that HetR could function as either an activator or repressor and that activation was cell-type specific. Taken together, we have expanded the direct HetR regulon and propose a model in which three categories of HetR binding sites, based on binding affinity and nucleotide sequence, contribute to three of the four phases of differentiation. PMID:24375104

  1. Instrumentation '79.

    ERIC Educational Resources Information Center

    Chemical and Engineering News, 1979

    1979-01-01

    Surveys the state of commerical development of analytical instrumentation as reflected by the Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy. Includes optical spectroscopy, liquid chromatography, magnetic spectrometers, and x-ray. (Author/MA)

  2. Astronomical instruments.

    NASA Astrophysics Data System (ADS)

    Rai, R. N.

    Indian astronomers have devised a number of instruments and the most important of these is the armillary sphere. The earliest armillary spheres were very simple instruments. Ptolemy in his Almagest enumerates at least three. The simplest of all was the equinoctial armilla. They had also the solstitial armilla which was a double ring, erected in the plane of the meridian with a rotating inner circle. This was used to measure the solar altitude.

  3. Oceanographic Instrument

    NASA Technical Reports Server (NTRS)

    1994-01-01

    Developed under NASA contract, the Fast Repetition Rate (FRR) fluorometer is a computer-controlled instrument for measuring the fluorescence of phytoplankton, microscopic plant forms that provide sustenance for animal life in the oceans. The fluorometer sensor is towed by ship through the water and the resulting printouts are compared with satellite data. The instrument is non-destructive and can be used in situ, providing scientific information on ocean activity and productivity.

  4. Escape from Het-6 Incompatibility in Neurospora Crassa Partial Diploids Involves Preferential Deletion within the Ectopic Segment

    PubMed Central

    Smith, M. L.; Yang, C. J.; Metzenberg, R. L.; Glass, N. L.

    1996-01-01

    Self-incompatible het-6(OR)/het-6(PA) partial diploids of Neurospora crassa were selected from a cross involving the translocation strain, T(IIL -> IIIR)AR18, and a normal sequence strain. About 25% of the partial diploids exhibited a marked increase in growth rate after 2 weeks, indicating that ``escape'' from het-6 incompatibility had occurred. Near isogenic tester strains with different alleles (het-6(OR) and het-6(PA)) were constructed and used to determine that 80 of 96 escape strains tested were het-6(PA), retaining the het-6 allele found in the normal-sequence LGII position; 16 were het-6(OR), retaining the allele in the translocated position. Restriction fragment length polymorphisms in 45 escape strains were examined with probes made from cosmids that spanned the translocated region. Along with electrophoretic analysis of chromosomes from three escape strains, RFLPs showed that escape is associated with deletion of part of one or the other of the duplicated DNA segments. Deletions ranged in size from ~70 kbp up to putatively the entire 270-kbp translocated region but always included a 35-kbp region wherein we hypothesize het-6 is located. The deletion spectrum at het-6 thus resembles other cases where mitotic deletions occur such as of tumor suppressor genes and of the hprt gene (coding for hypoxanthine-guanine phosphoribosyl-transferase) in humans. PMID:8889517

  5. Measuring space radiation with ADIS instruments

    NASA Astrophysics Data System (ADS)

    Connell, J. J.; Lopate, C.; McKibben, R. B.; Merk, J.

    2010-09-01

    Measurements of radiation in space, cosmic rays and Solar energetic particles, date back to the dawn of space flight. Solid state detectors, the basis of most modern high energy charged particle instruments, first flew in space in the 1960's. Modern particle spectrometers, such as ACE/CRIS, ACE/SIS and Ulysses/HET, can measure the elemental and isotopic composition of ions through the iron peak. This is achieved by using position sensing detectors (PSD's) arranged into hodoscopes to measure particle trajectories through the instrument, allowing for pathlength corrections to energy loss measurements. The Angle Detecting Inclined Sensor (ADIS) technique measures particle angle of incidence using a simple system of detectors inclined to the instrument axis. It achieves elemental resolution well beyond iron, and isotopic resolution for moderate mass elements without the complexity of position sensing detectors. An ADIS instrument was selected to fly as the High Energy Particle Sensor (HEPS) on NPOESS, but was de-scoped with the rest of the space weather suite. Another ADIS instrument, the Energetic Heavy Ion Sensor (EHIS), is being developed for GOES-R. UNH has built and tested a engineering unit of the EHIS. Applications for manned dosimetery on the Crew Exploration Vehicle (CEV) are also being explored. The basic ADIS technique is explained and accelerator data for heavy ions shown.

  6. Instrumented SSH

    SciTech Connect

    Campbell, Scott; Campbell, Scott

    2009-05-27

    NERSC recently undertook a project to access and analyze Secure Shell (SSH) related data. This includes authentication data such as user names and key fingerprints, interactive session data such as keystrokes and responses, and information about noninteractive sessions such as commands executed and files transferred. Historically, this data has been inaccessible with traditional network monitoring techniques, but with a modification to the SSH daemon, this data can be passed directly to intrusion detection systems for analysis. The instrumented version of SSH is now running on all NERSC production systems. This paper describes the project, details about how SSH was instrumented, and the initial results of putting this in production.

  7. Geoscience instrumentation

    NASA Technical Reports Server (NTRS)

    Wolff, E. A. (Editor); Mercanti, E. P.

    1974-01-01

    Geoscience instrumentation systems are considered along with questions of geoscience environment, signal processing, data processing, and design problems. Instrument platforms are examined, taking into account ground platforms, airborne platforms, ocean platforms, and space platforms. In situ and laboratory sensors described include acoustic wave sensors, age sensors, atmospheric constituent sensors, biological sensors, cloud particle sensors, electric field sensors, electromagnetic field sensors, precision geodetic sensors, gravity sensors, ground constituent sensors, horizon sensors, humidity sensors, ion and electron sensors, magnetic field sensors, tide sensors, and wind sensors. Remote sensors are discussed, giving attention to sensing techniques, acoustic echo-sounders, gamma ray sensors, optical sensors, radar sensors, and microwave radiometric sensors.

  8. Geotechnical instrumentation

    NASA Astrophysics Data System (ADS)

    Green, G. E.; Mikkelsen, P. E.; Mayne, P. W.; Frost, D. D.; Dowding, C. H.

    1988-12-01

    The 11 papers in the report deal with the following areas: deformation measurements with inclinometers; dilatometer experience in Washington, D.C., and vicinity; ground vibration monitoring instrumentation and computerized surveillance; instrumentation for tests of piles subjected to axial loading; use of the wave equation by the North Carolina Department of Transportation; NYSDOT's construction control of pile foundations with dynamic pile testing; discussion of procedures for the determination of pile capacity; modern specification of driven pile work; analysis of laterally loaded piles with nonlinear bending behavior; unified design of piles and pile groups, and LTBASE, a computer program for the analysis of laterally loaded piers including base and slope effects.

  9. Research Instruments

    NASA Technical Reports Server (NTRS)

    1992-01-01

    The GENETI-SCANNER, newest product of Perceptive Scientific Instruments, Inc. (PSI), rapidly scans slides, locates, digitizes, measures and classifies specific objects and events in research and diagnostic applications. Founded by former NASA employees, PSI's primary product line is based on NASA image processing technology. The instruments karyotype - a process employed in analysis and classification of chromosomes - using a video camera mounted on a microscope. Images are digitized, enabling chromosome image enhancement. The system enables karyotyping to be done significantly faster, increasing productivity and lowering costs. Product is no longer being manufactured.

  10. Structural insights into HetR-PatS interaction involved in cyanobacterial pattern formation.

    PubMed

    Hu, Hai-Xi; Jiang, Yong-Liang; Zhao, Meng-Xi; Cai, Kun; Liu, Sanling; Wen, Bin; Lv, Pei; Zhang, Yonghui; Peng, Junhui; Zhong, Hui; Yu, Hong-Mei; Ren, Yan-Min; Zhang, Zhiyong; Tian, Changlin; Wu, Qingfa; Oliveberg, Mikael; Zhang, Cheng-Cai; Chen, Yuxing; Zhou, Cong-Zhao

    2015-01-01

    The one-dimensional pattern of heterocyst in the model cyanobacterium Anabaena sp. PCC 7120 is coordinated by the transcription factor HetR and PatS peptide. Here we report the complex structures of HetR binding to DNA, and its hood domain (HetRHood) binding to a PatS-derived hexapeptide (PatS6) at 2.80 and 2.10 Å, respectively. The intertwined HetR dimer possesses a couple of novel HTH motifs, each of which consists of two canonical α-helices in the DNA-binding domain and an auxiliary α-helix from the flap domain of the neighboring subunit. Two PatS6 peptides bind to the lateral clefts of HetRHood, and trigger significant conformational changes of the flap domain, resulting in dissociation of the auxiliary α-helix and eventually release of HetR from the DNA major grove. These findings provide the structural insights into a prokaryotic example of Turing model. PMID:26576507

  11. Structural insights into HetR−PatS interaction involved in cyanobacterial pattern formation

    PubMed Central

    Hu, Hai-Xi; Jiang, Yong-Liang; Zhao, Meng-Xi; Cai, Kun; Liu, Sanling; Wen, Bin; Lv, Pei; Zhang, Yonghui; Peng, Junhui; Zhong, Hui; Yu, Hong-Mei; Ren, Yan-Min; Zhang, Zhiyong; Tian, Changlin; Wu, Qingfa; Oliveberg, Mikael; Zhang, Cheng-Cai; Chen, Yuxing; Zhou, Cong-Zhao

    2015-01-01

    The one-dimensional pattern of heterocyst in the model cyanobacterium Anabaena sp. PCC 7120 is coordinated by the transcription factor HetR and PatS peptide. Here we report the complex structures of HetR binding to DNA, and its hood domain (HetRHood) binding to a PatS-derived hexapeptide (PatS6) at 2.80 and 2.10 Å, respectively. The intertwined HetR dimer possesses a couple of novel HTH motifs, each of which consists of two canonical α-helices in the DNA-binding domain and an auxiliary α-helix from the flap domain of the neighboring subunit. Two PatS6 peptides bind to the lateral clefts of HetRHood, and trigger significant conformational changes of the flap domain, resulting in dissociation of the auxiliary α-helix and eventually release of HetR from the DNA major grove. These findings provide the structural insights into a prokaryotic example of Turing model. PMID:26576507

  12. Weather Instruments.

    ERIC Educational Resources Information Center

    Brantley, L. Reed, Sr.; Demanche, Edna L.; Klemm, E. Barbara; Kyselka, Will; Phillips, Edwin A.; Pottenger, Francis M.; Yamamoto, Karen N.; Young, Donald B.

    This booklet presents some activities to measure various weather phenomena. Directions for constructing a weather station are included. Instruments including rain gauges, thermometers, wind vanes, wind speed devices, humidity devices, barometers, atmospheric observations, a dustfall jar, sticky-tape can, detection of gases in the air, and pH of…

  13. RHIC instrumentation

    SciTech Connect

    Shea, T. J.; Witkover, R. L.

    1998-12-10

    The Relativistic Heavy Ion Collider (RHIC) consists of two 3.8 km circumference rings utilizing 396 superconducting dipoles and 492 superconducting quadrupoles. Each ring will accelerate approximately 60 bunches of 10{sup 11} protons to 250 GeV, or 10{sup 9} fully stripped gold ions to 100 GeV/nucleon. Commissioning is scheduled for early 1999 with detectors for some of the 6 intersection regions scheduled for initial operation later in the year. The injection line instrumentation includes: 52 beam position monitor (BPM) channels, 56 beam loss monitor (BLM) channels, 5 fast integrating current transformers and 12 video beam profile monitors. The collider ring instrumentation includes: 667 BPM channels, 400 BLM channels, wall current monitors, DC current transformers, ionization profile monitors (IPMs), transverse feedback systems, and resonant Schottky monitors. The use of superconducting magnets affected the beam instrumentation design. The BPM electrodes must function in a cryogenic environment and the BLM system must prevent magnet quenches from either fast or slow losses with widely different rates. RHIC is the first superconducting accelerator to cross transition, requiring close monitoring of beam parameters at this time. High space-charge due to the fully stripped gold ions required the IPM to collect magnetically guided electrons rather than the conventional ions. Since polarized beams will also be accelerated in RHIC, additional constraints were put on the instrumentation. The orbit must be well controlled to minimize depolarizing resonance strengths. Also, the position monitors must accommodate large orbit displacements within the Siberian snakes and spin rotators. The design of the instrumentation will be presented along with results obtained during bench tests, the injection line commissioning, and the first sextant test.

  14. RHIC instrumentation

    NASA Astrophysics Data System (ADS)

    Shea, T. J.; Witkover, R. L.

    1998-12-01

    The Relativistic Heavy Ion Collider (RHIC) consists of two 3.8 km circumference rings utilizing 396 superconducting dipoles and 492 superconducting quadrupoles. Each ring will accelerate approximately 60 bunches of 1011 protons to 250 GeV, or 109 fully stripped gold ions to 100 GeV/nucleon. Commissioning is scheduled for early 1999 with detectors for some of the 6 intersection regions scheduled for initial operation later in the year. The injection line instrumentation includes: 52 beam position monitor (BPM) channels, 56 beam loss monitor (BLM) channels, 5 fast integrating current transformers and 12 video beam profile monitors. The collider ring instrumentation includes: 667 BPM channels, 400 BLM channels, wall current monitors, DC current transformers, ionization profile monitors (IPMs), transverse feedback systems, and resonant Schottky monitors. The use of superconducting magnets affected the beam instrumentation design. The BPM electrodes must function in a cryogenic environment and the BLM system must prevent magnet quenches from either fast or slow losses with widely different rates. RHIC is the first superconducting accelerator to cross transition, requiring close monitoring of beam parameters at this time. High space-charge due to the fully stripped gold ions required the IPM to collect magnetically guided electrons rather than the conventional ions. Since polarized beams will also be accelerated in RHIC, additional constraints were put on the instrumentation. The orbit must be well controlled to minimize depolarizing resonance strengths. Also, the position monitors must accommodate large orbit displacements within the Siberian snakes and spin rotators. The design of the instrumentation will be presented along with results obtained during bench tests, the injection line commissioning, and the first sextant test.

  15. RHIC instrumentation

    SciTech Connect

    Shea, T.J.; Witkover, R.L.

    1998-12-01

    The Relativistic Heavy Ion Collider (RHIC) consists of two 3.8 km circumference rings utilizing 396 superconducting dipoles and 492 superconducting quadrupoles. Each ring will accelerate approximately 60 bunches of 10{sup 11} protons to 250 GeV, or 10{sup 9} fully stripped gold ions to 100 GeV/nucleon. Commissioning is scheduled for early 1999 with detectors for some of the 6 intersection regions scheduled for initial operation later in the year. The injection line instrumentation includes: 52 beam position monitor (BPM) channels, 56 beam loss monitor (BLM) channels, 5 fast integrating current transformers and 12 video beam profile monitors. The collider ring instrumentation includes: 667 BPM channels, 400 BLM channels, wall current monitors, DC current transformers, ionization profile monitors (IPMs), transverse feedback systems, and resonant Schottky monitors. The use of superconducting magnets affected the beam instrumentation design. The BPM electrodes must function in a cryogenic environment and the BLM system must prevent magnet quenches from either fast or slow losses with widely different rates. RHIC is the first superconducting accelerator to cross transition, requiring close monitoring of beam parameters at this time. High space-charge due to the fully stripped gold ions required the IPM to collect magnetically guided electrons rather than the conventional ions. Since polarized beams will also be accelerated in RHIC, additional constraints were put on the instrumentation. The orbit must be well controlled to minimize depolarizing resonance strengths. Also, the position monitors must accommodate large orbit displacements within the Siberian snakes and spin rotators. The design of the instrumentation will be presented along with results obtained during bench tests, the injection line commissioning, and the first sextant test. {copyright} {ital 1998 American Institute of Physics.}

  16. Analyzing the Birth and Propagation of Two Distinct Prions, [PSI+] and [Het-s]y, in Yeast

    PubMed Central

    Mathur, Vidhu; Taneja, Vibha; Sun, Yidi

    2010-01-01

    Various proteins, like the infectious yeast prions and the noninfectious human Huntingtin protein (with expanded polyQ), depend on a Gln or Asn (QN)-rich region for amyloid formation. Other prions, e.g., mammalian PrP and the [Het-s] prion of Podospora anserina, although still able to form infectious amyloid aggregates, do not have QN-rich regions. Furthermore, [Het-s] and yeast prions appear to differ dramatically in their amyloid conformation. Despite these differences, a fusion of the Het-s prion domain to GFP (Het-sPrD-GFP) can propagate in yeast as a prion called [Het-s]y. We analyzed the properties of two divergent prions in yeast: [Het-s]y and the native yeast prion [PSI+] (prion form of translational termination factor Sup35). Curiously, the induced appearance and transmission of [PSI+] and [Het-s]y aggregates is remarkably similar. Overexpression of tagged prion protein (Sup35-GFP or Het-sPrD-GFP) in nonprion cells gives rise to peripheral, and later internal, ring/mesh-like aggregates. The cells with these ring-like aggregates give rise to daughters with one (perivacuolar) or two (perivacuolar and juxtanuclear) dot-like aggregates per cell. These line, ring, mesh, and dot aggregates are not really the transmissible prion species and should only be regarded as phenotypic markers of the presence of the prions. Both [PSI+] and [Het-s]y first appear in daughters as numerous tiny dot-like aggregates, and both require the endocytic protein, Sla2, for ring formation, but not propagation. PMID:20219972

  17. Relationships between the ABC-Exporter HetC and Peptides that Regulate the Spatiotemporal Pattern of Heterocyst Distribution in Anabaena

    PubMed Central

    Corrales-Guerrero, Laura; Flores, Enrique; Herrero, Antonia

    2014-01-01

    In the model cyanobacterium Anabaena sp. PCC 7120, cells called heterocysts that are specialized in the fixation of atmospheric nitrogen differentiate from vegetative cells of the filament in the absence of combined nitrogen. Heterocysts follow a specific distribution pattern along the filament, and a number of regulators have been identified that influence the heterocyst pattern. PatS and HetN, expressed in the differentiating cells, inhibit the differentiation of neighboring cells. At least PatS appears to be processed and transferred from cell to cell. HetC is similar to ABC exporters and is required for differentiation. We present an epistasis analysis of these regulatory genes and of genes, hetP and asr2819, successively downstream from hetC, and we have studied the localization of HetC and HetP by use of GFP fusions. Inactivation of patS, but not of hetN, allowed differentiation to proceed in a hetC background, whereas inactivation of hetC in patS or patS hetN backgrounds decreased the frequency of contiguous proheterocysts. A HetC-GFP protein is localized to the heterocysts and especially near their cell poles, and a putative HetC peptidase domain was required for heterocyst differentiation but not for HetC-GFP localization. hetP is also required for heterocyst differentiation. A HetP-GFP protein localized mostly near the heterocyst poles. ORF asr2819, which we denote patC, encodes an 84-residue peptide and is induced upon nitrogen step-down. Inactivation of patC led to a late spreading of the heterocyst pattern. Whereas HetC and HetP appear to have linked functions that allow heterocyst differentiation to progress, PatC may have a role in selecting sites of differentiation, suggesting that these closely positioned genes may be functionally related. PMID:25121608

  18. Relationships between the ABC-exporter HetC and peptides that regulate the spatiotemporal pattern of heterocyst distribution in Anabaena.

    PubMed

    Corrales-Guerrero, Laura; Flores, Enrique; Herrero, Antonia

    2014-01-01

    In the model cyanobacterium Anabaena sp. PCC 7120, cells called heterocysts that are specialized in the fixation of atmospheric nitrogen differentiate from vegetative cells of the filament in the absence of combined nitrogen. Heterocysts follow a specific distribution pattern along the filament, and a number of regulators have been identified that influence the heterocyst pattern. PatS and HetN, expressed in the differentiating cells, inhibit the differentiation of neighboring cells. At least PatS appears to be processed and transferred from cell to cell. HetC is similar to ABC exporters and is required for differentiation. We present an epistasis analysis of these regulatory genes and of genes, hetP and asr2819, successively downstream from hetC, and we have studied the localization of HetC and HetP by use of GFP fusions. Inactivation of patS, but not of hetN, allowed differentiation to proceed in a hetC background, whereas inactivation of hetC in patS or patS hetN backgrounds decreased the frequency of contiguous proheterocysts. A HetC-GFP protein is localized to the heterocysts and especially near their cell poles, and a putative HetC peptidase domain was required for heterocyst differentiation but not for HetC-GFP localization. hetP is also required for heterocyst differentiation. A HetP-GFP protein localized mostly near the heterocyst poles. ORF asr2819, which we denote patC, encodes an 84-residue peptide and is induced upon nitrogen step-down. Inactivation of patC led to a late spreading of the heterocyst pattern. Whereas HetC and HetP appear to have linked functions that allow heterocyst differentiation to progress, PatC may have a role in selecting sites of differentiation, suggesting that these closely positioned genes may be functionally related.

  19. Relationships between the ABC-exporter HetC and peptides that regulate the spatiotemporal pattern of heterocyst distribution in Anabaena.

    PubMed

    Corrales-Guerrero, Laura; Flores, Enrique; Herrero, Antonia

    2014-01-01

    In the model cyanobacterium Anabaena sp. PCC 7120, cells called heterocysts that are specialized in the fixation of atmospheric nitrogen differentiate from vegetative cells of the filament in the absence of combined nitrogen. Heterocysts follow a specific distribution pattern along the filament, and a number of regulators have been identified that influence the heterocyst pattern. PatS and HetN, expressed in the differentiating cells, inhibit the differentiation of neighboring cells. At least PatS appears to be processed and transferred from cell to cell. HetC is similar to ABC exporters and is required for differentiation. We present an epistasis analysis of these regulatory genes and of genes, hetP and asr2819, successively downstream from hetC, and we have studied the localization of HetC and HetP by use of GFP fusions. Inactivation of patS, but not of hetN, allowed differentiation to proceed in a hetC background, whereas inactivation of hetC in patS or patS hetN backgrounds decreased the frequency of contiguous proheterocysts. A HetC-GFP protein is localized to the heterocysts and especially near their cell poles, and a putative HetC peptidase domain was required for heterocyst differentiation but not for HetC-GFP localization. hetP is also required for heterocyst differentiation. A HetP-GFP protein localized mostly near the heterocyst poles. ORF asr2819, which we denote patC, encodes an 84-residue peptide and is induced upon nitrogen step-down. Inactivation of patC led to a late spreading of the heterocyst pattern. Whereas HetC and HetP appear to have linked functions that allow heterocyst differentiation to progress, PatC may have a role in selecting sites of differentiation, suggesting that these closely positioned genes may be functionally related. PMID:25121608

  20. Spatial Fluctuations in Expression of the Heterocyst Differentiation Regulatory Gene hetR in Anabaena Filaments

    PubMed Central

    Corrales-Guerrero, Laura; Tal, Asaf; Arbel-Goren, Rinat; Mariscal, Vicente; Flores, Enrique; Herrero, Antonia; Stavans, Joel

    2015-01-01

    Under nitrogen deprivation, filaments of the cyanobacterium Anabaena undergo a process of development, resulting in a one-dimensional pattern of nitrogen-fixing heterocysts separated by about ten photosynthetic vegetative cells. Many aspects of gene expression before nitrogen deprivation and during the developmental process remain to be elucidated. Furthermore, the coupling of gene expression fluctuations between cells along a multicellular filament is unknown. We studied the statistics of fluctuations of gene expression of HetR, a transcription factor essential for heterocyst differentiation, both under steady-state growth in nitrogen-rich conditions and at different times following nitrogen deprivation, using a chromosomally-encoded translational hetR-gfp fusion. Statistical analysis of fluorescence at the individual cell level in wild-type and mutant filaments demonstrates that expression fluctuations of hetR in nearby cells are coupled, with a characteristic spatial range of circa two to three cells, setting the scale for cellular interactions along a filament. Correlations between cells predominantly arise from intercellular molecular transfer and less from cell division. Fluctuations after nitrogen step-down can build up on those under nitrogen-replete conditions. We found that under nitrogen-rich conditions, basal, steady-state expression of the HetR inhibitor PatS, cell-cell communication influenced by the septal protein SepJ and positive HetR auto-regulation are essential determinants of fluctuations in hetR expression and its distribution along filaments. A comparison between the expression of hetR-gfp under nitrogen-rich and nitrogen-poor conditions highlights the differences between the two HetR inhibitors PatS and HetN, as well as the differences in specificity between the septal proteins SepJ and FraC/FraD. Activation, inhibition and cell-cell communication lie at the heart of developmental processes. Our results show that proteins involved in these

  1. Spatial fluctuations in expression of the heterocyst differentiation regulatory gene hetR in Anabaena filaments.

    PubMed

    Corrales-Guerrero, Laura; Tal, Asaf; Arbel-Goren, Rinat; Mariscal, Vicente; Flores, Enrique; Herrero, Antonia; Stavans, Joel

    2015-04-01

    Under nitrogen deprivation, filaments of the cyanobacterium Anabaena undergo a process of development, resulting in a one-dimensional pattern of nitrogen-fixing heterocysts separated by about ten photosynthetic vegetative cells. Many aspects of gene expression before nitrogen deprivation and during the developmental process remain to be elucidated. Furthermore, the coupling of gene expression fluctuations between cells along a multicellular filament is unknown. We studied the statistics of fluctuations of gene expression of HetR, a transcription factor essential for heterocyst differentiation, both under steady-state growth in nitrogen-rich conditions and at different times following nitrogen deprivation, using a chromosomally-encoded translational hetR-gfp fusion. Statistical analysis of fluorescence at the individual cell level in wild-type and mutant filaments demonstrates that expression fluctuations of hetR in nearby cells are coupled, with a characteristic spatial range of circa two to three cells, setting the scale for cellular interactions along a filament. Correlations between cells predominantly arise from intercellular molecular transfer and less from cell division. Fluctuations after nitrogen step-down can build up on those under nitrogen-replete conditions. We found that under nitrogen-rich conditions, basal, steady-state expression of the HetR inhibitor PatS, cell-cell communication influenced by the septal protein SepJ and positive HetR auto-regulation are essential determinants of fluctuations in hetR expression and its distribution along filaments. A comparison between the expression of hetR-gfp under nitrogen-rich and nitrogen-poor conditions highlights the differences between the two HetR inhibitors PatS and HetN, as well as the differences in specificity between the septal proteins SepJ and FraC/FraD. Activation, inhibition and cell-cell communication lie at the heart of developmental processes. Our results show that proteins involved in these

  2. Spatial fluctuations in expression of the heterocyst differentiation regulatory gene hetR in Anabaena filaments.

    PubMed

    Corrales-Guerrero, Laura; Tal, Asaf; Arbel-Goren, Rinat; Mariscal, Vicente; Flores, Enrique; Herrero, Antonia; Stavans, Joel

    2015-04-01

    Under nitrogen deprivation, filaments of the cyanobacterium Anabaena undergo a process of development, resulting in a one-dimensional pattern of nitrogen-fixing heterocysts separated by about ten photosynthetic vegetative cells. Many aspects of gene expression before nitrogen deprivation and during the developmental process remain to be elucidated. Furthermore, the coupling of gene expression fluctuations between cells along a multicellular filament is unknown. We studied the statistics of fluctuations of gene expression of HetR, a transcription factor essential for heterocyst differentiation, both under steady-state growth in nitrogen-rich conditions and at different times following nitrogen deprivation, using a chromosomally-encoded translational hetR-gfp fusion. Statistical analysis of fluorescence at the individual cell level in wild-type and mutant filaments demonstrates that expression fluctuations of hetR in nearby cells are coupled, with a characteristic spatial range of circa two to three cells, setting the scale for cellular interactions along a filament. Correlations between cells predominantly arise from intercellular molecular transfer and less from cell division. Fluctuations after nitrogen step-down can build up on those under nitrogen-replete conditions. We found that under nitrogen-rich conditions, basal, steady-state expression of the HetR inhibitor PatS, cell-cell communication influenced by the septal protein SepJ and positive HetR auto-regulation are essential determinants of fluctuations in hetR expression and its distribution along filaments. A comparison between the expression of hetR-gfp under nitrogen-rich and nitrogen-poor conditions highlights the differences between the two HetR inhibitors PatS and HetN, as well as the differences in specificity between the septal proteins SepJ and FraC/FraD. Activation, inhibition and cell-cell communication lie at the heart of developmental processes. Our results show that proteins involved in these

  3. Structures of complexes comprised of Fischerella transcription factor HetR with Anabaena DNA targets.

    PubMed

    Kim, Youngchang; Ye, Zi; Joachimiak, Grazyna; Videau, Patrick; Young, Jasmine; Hurd, Kathryn; Callahan, Sean M; Gornicki, Piotr; Zhao, Jindong; Haselkorn, Robert; Joachimiak, Andrzej

    2013-05-01

    HetR is an essential regulator of heterocyst development in cyanobacteria. Many mutations in HetR render Anabaena incapable of nitrogen fixation. The protein binds to a DNA palindrome upstream of hetP and other genes. We have determined the crystal structures of HetR complexed with palindromic DNA targets, 21, 23, and 29 bp at 2.50-, 3.00-, and 3.25-Å resolution, respectively. The highest-resolution structure shows fine details of specific protein-DNA interactions. The lower-resolution structures with longer DNA duplexes have similar interaction patterns and show how the flap domains interact with DNA in a sequence nonspecific fashion. Fifteen of 15 protein-DNA contacts predicted on the basis of the structure were confirmed by single amino acid mutations that abolished binding in vitro and complementation in vivo. A striking feature of the structure is the association of glutamate 71 from each subunit of the HetR dimer with three successive cytosines in each arm of the palindromic target, a feature that is conserved among all known heterocyst-forming cyanobacteria sequenced to date. PMID:23610410

  4. [Editing of articles accepted for publication by the Nederlands Tijdschrift voor Geneeskunde].

    PubMed

    Walvoort, H C

    1997-01-01

    The Nederlands Tijdschrift voor Geneeskunde has been publishing medical science in Dutch for 140 years. To bridge the gap between the specialist science and the general medical reader several sections in the accepted papers have to be clarified, simplified and shortened by post acceptance editing. The style and language of the authors is treated with respect. Changes are made if the article does not comply with internationally accepted rules on scientific reporting, if the article can not be understood using currently authoritative general and medical books of reference, and if its language does not comply with generally accepted Dutch rules for grammar and spelling.

  5. Spinal instrumentation.

    PubMed

    Spivak, J M; Balderston, R A

    1994-03-01

    The past decade has seen a dramatic increase in the availability of spinal instrumentation devices, enabling surgeons to treat a variety of spinal disorders with improved results and lower morbidity. In each anatomic region new fixation systems exist. Improvement in fusion rates with supplemental plate fixation following anterior cervical diskectomies and reconstructions has been demonstrated; these devices can now be applied more safely than ever before. Posterior occipitocervical plating to the C-2 pedicle and C3-6 lateral masses can provide stable fixation despite incompetent posterior arch bony structures. Newer, more rigid anterior thoracolumbar instrumentation allows for correction of thoracolumbar and lumbar scoliosis along fewer levels and with better maintenance of lordosis and is also useful following anterior decompression for tumor and trauma. Segmental hook fixation of the posterior thoracolumbar spine has allowed for improved correction of deformity without increased morbidity or the need for postoperative bracing in many cases. Finally, the use of transpedicular screw fixation of the lumbosacral spine allows for excellent segmental fixation without intact posterior elements, including facet joints, and has significantly improved the fusion rate in lumbosacral fusions. PMID:8024965

  6. Optical Instruments

    NASA Technical Reports Server (NTRS)

    1990-01-01

    Precision Lapping and Optical Co. has developed a wide variety of hollow retroreflector systems for applications involving the entire optical spectrum; they are, according to company literature, cheaper, more accurate, lighter and capable of greater size than solid prisms. Precision Lapping's major customers are aerospace and defense companies, government organizations, R&D and commercial instrument companies. For example, Precision Lapping supplies hollow retroreflectors for the laser fire control system of the Army's Abrams tank, and retroreflectors have been and are being used in a number of space tests relative to the Air Force's Strategic Defense Initiative research program. An example of a customer/user is Chesapeake Laser Systems, producer of the Laser Tracker System CMS-2000, which has applications in SDI research and industrial robotics. Another customer is MDA Scientific, Inc., manufacturer of a line of toxic gas detection systems used to monitor hazardous gases present in oil fields, refineries, offshore platforms, chemical plants, waste storage sites and other locations where gases are released into the environment.

  7. Inactivation of the Podospora anserina vegetative incompatibility locus het-c, whose product resembles a glycolipid transfer protein, drastically impairs ascospore production.

    PubMed Central

    Saupe, S; Descamps, C; Turcq, B; Bégueret, J

    1994-01-01

    The het-c locus contains different alleles that elicit nonallelic vegetative incompatibility through specific interactions with alleles of the unlinked loci het-e and het-d. The het-c2 allele has been cloned. It encodes a 208-amino acid polypeptide that is similar to a glycolipid transfer protein purified from pig brain. Disruption of this gene drastically impairs ascospore production in homozygous crosses, and some mutants exhibit abnormal branching of apical hyphae. The protein encoded by het-c2 is essential in the biology of the fungus and may be involved in cell-wall biosynthesis. Images PMID:8016091

  8. HET-CAM test for determining the possible eye irritancy of pesticides.

    PubMed

    Budai, Péter; Lehel, József; Tavaszi, Judit; Kormos, Eva

    2010-09-01

    Agrochemicals and veterinary products must undergo numerous toxicological tests before registration. The use of animals in these studies is a controversial issue. The Draize eye irritation test is one of the most criticised methods because of the injuries inflicted on the test animals. Several in vitro methods have been used to investigate the toxicity of potential eye irritants with a view to replacing in vivo eye irritation testing. One of these alternative methods is the Hen's Egg Test--Chorioallantoic Membrane (HET-CAM) test. In the present studies comparative screening was performed with a set of agrochemicals to establish parallel data on in vitro (HET-CAM) and in vivo (Draize) results. The examined materials were: Totril (ioxynil), Omite 57 E (propargit), Actellic 50 EC (pyrimiphos-methyl), Stomp 330 EC (pendimethalin), Mospilan 3 EC (acetamiprid), Alirox 80 EC (EPTC), Match 050 EC (lufenuron), Nonit (dioctyl sulphosuccinate sodium), Perenal (haloxyfop-R methyl ester), Pyrinex 48 EC (chlorpyrifos). These experiments showed good correlation between results obtained by the HET-CAM test and those of the Draize rabbit eye test in most cases. The present form of the HET-CAM test can be proposed as a pre-screening method for the determination of eye irritative potential, therefore the number of test animals can be reduced and/or experimental animals can be replaced. PMID:20713327

  9. The heterocyst differentiation transcriptional regulator HetR of the filamentous cyanobacterium Anabaena forms tetramers and can be regulated by phosphorylation.

    PubMed

    Valladares, Ana; Flores, Enrique; Herrero, Antonia

    2016-02-01

    Many filamentous cyanobacteria respond to the external cue of nitrogen scarcity by the differentiation of heterocysts, cells specialized in the fixation of atmospheric nitrogen in oxic environments. Heterocysts follow a spatial pattern along the filament of two heterocysts separated by ca. 10-15 vegetative cells performing oxygenic photosynthesis. HetR is a transcriptional regulator that directs heterocyst differentiation. In the model strain Anabaena sp. PCC 7120, the HetR protein was observed in various oligomeric forms in vivo, including a tetramer that peaked with maximal hetR expression during differentiation. Tetramers were not detected in a hetR point mutant incapable of differentiation, but were conspicuous in an over-differentiating strain lacking the PatS inhibitor. In differentiated filaments the HetR tetramer was restricted to heterocysts, being undetectable in vegetative cells. HetR co-purified with RNA polymerase from Anabaena mainly as a tetramer. In vitro, purified recombinant HetR was distributed between monomers, dimers, trimers and tetramers, and it was phosphorylated when incubated with (γ-(32)P)ATP. Phosphorylation and PatS hampered the accumulation of HetR tetramers and impaired HetR binding to DNA. In summary, tetrameric HetR appears to represent a functionally relevant form of HetR, whose abundance in the Anabaena filament could be negatively regulated by phosphorylation and by PatS.

  10. The heterocyst differentiation transcriptional regulator HetR of the filamentous cyanobacterium Anabaena forms tetramers and can be regulated by phosphorylation.

    PubMed

    Valladares, Ana; Flores, Enrique; Herrero, Antonia

    2016-02-01

    Many filamentous cyanobacteria respond to the external cue of nitrogen scarcity by the differentiation of heterocysts, cells specialized in the fixation of atmospheric nitrogen in oxic environments. Heterocysts follow a spatial pattern along the filament of two heterocysts separated by ca. 10-15 vegetative cells performing oxygenic photosynthesis. HetR is a transcriptional regulator that directs heterocyst differentiation. In the model strain Anabaena sp. PCC 7120, the HetR protein was observed in various oligomeric forms in vivo, including a tetramer that peaked with maximal hetR expression during differentiation. Tetramers were not detected in a hetR point mutant incapable of differentiation, but were conspicuous in an over-differentiating strain lacking the PatS inhibitor. In differentiated filaments the HetR tetramer was restricted to heterocysts, being undetectable in vegetative cells. HetR co-purified with RNA polymerase from Anabaena mainly as a tetramer. In vitro, purified recombinant HetR was distributed between monomers, dimers, trimers and tetramers, and it was phosphorylated when incubated with (γ-(32)P)ATP. Phosphorylation and PatS hampered the accumulation of HetR tetramers and impaired HetR binding to DNA. In summary, tetrameric HetR appears to represent a functionally relevant form of HetR, whose abundance in the Anabaena filament could be negatively regulated by phosphorylation and by PatS. PMID:26552991

  11. Low activated incore instrument

    DOEpatents

    Ekeroth, D.E.

    1994-04-19

    Instrumentation is described for nuclear reactor head-mounted incore instrumentation systems fabricated of low nuclear cross section materials (i.e., zirconium or titanium). The instrumentation emits less radiation than that fabricated of conventional materials. 9 figures.

  12. Low activated incore instrument

    DOEpatents

    Ekeroth, Douglas E.

    1994-01-01

    Instrumentation for nuclear reactor head-mounted incore instrumentation systems fabricated of low nuclear cross section materials (i.e., zirconium or titanium). The instrumentation emits less radiation than that fabricated of conventional materials.

  13. Evaluating musical instruments

    SciTech Connect

    Campbell, D. Murray

    2014-04-01

    Scientific measurements of sound generation and radiation by musical instruments are surprisingly hard to correlate with the subtle and complex judgments of instrumental quality made by expert musicians.

  14. Analysis and Verification of HET 1 m Mirror Deflections Due to Edge Sensor Loading

    NASA Technical Reports Server (NTRS)

    Stallcup, Michael A.; Whitaker, Ann F. (Technical Monitor)

    2001-01-01

    The ninety-one 1 m mirror segments which comprise the McDonald Observatory Hobby Eberly Telescope (HET) primary mirror have been observed to drift out of alignment in an unpredictable manner in response to time variant temperature deviations. A Segment Alignment Maintenance System (SAMS) is being developed to detect and correct this segment-to-segment drift using sensors mounted at the edges of the mirror segments. However, the segments were not originally designed to carry the weight of edge sensors. Thus, analyses and tests were conducted as part of the SAMS design to estimate the magnitude and shape of the edge sensor induced deformations as well as the resultant optical performance. Interferometric testing of a 26 m radius of curvature HET mirror segment was performed at the Marshall Space Flight Center using several load conditions to verify the finite element analyses.

  15. Searching for cosmic ray latitude gradients with the Ulysses COSPIN High Energy Telescope (HET) during Ulysses' fast latitude scan in 2007-2008

    NASA Astrophysics Data System (ADS)

    McKibben, R. Bruce; Connell, James; Zhang, Ming

    Between February 2007 and January 2008, Ulysses traversed all heliographic latitudes between 79.7° S and 79.7° N at radii between 2.35 and 1.39 AU. This so-called fast latitude scan (FLS) provided a snapshot of the latitudinal intensity structure of modulated galactic cosmic rays in the inner heliosphere in a time short compared to significant evolution of the solar activity cycle, which is now near its minimum phase. Previous fast latitude scans were performed near solar maximum in 2000-2001, and near solar minimum in 1994-1995, when the sign of the solar dipole was opposite to that observed during the current solar minimum. In 1994-1995, small but clear increases in intensity from the equator towards the poles were measured by the HET for the integral intensity of cosmic rays >92 MeV and for helium above about 35 MeV/n, consistent in sign, if not in magnitude, with the positive latitudinal gradients predicted for that sign of the solar dipole by then-current modulation models that included the effects of gradient and curvature drifts. The opposite polarity of the solar dipole in this solar minimum was expected to lead to gradients of opposite sign, with intensities decreasing towards the poles. However in a preliminary report of our results through October 2007 (McKibben et al., AGU Fall Mtg, 2007), based on comparison of measurements of protons, helium, and heavy ions from the Ulysses HET with similar measurements near 1 AU and in the ecliptic from the SOHO/EPHIN and ACE/CRIS instruments no gradients of either sign were apparent. In this report we extend our results to include the complete 2007-2008 fast latitude scan, perform more extensive analysis to search for evidence of even small gradients, and discuss the significance of our results. This work was supported in part by NASA Contract 1247101.

  16. IOT Overview: IR Instruments

    NASA Astrophysics Data System (ADS)

    Mason, E.

    In this instrument review chapter the calibration plans of ESO IR instruments are presented and briefly reviewed focusing, in particular, on the case of ISAAC, which has been the first IR instrument at VLT and whose calibration plan served as prototype for the coming instruments.

  17. Astronomical Instruments in India

    NASA Astrophysics Data System (ADS)

    Sarma, Sreeramula Rajeswara

    The earliest astronomical instruments used in India were the gnomon and the water clock. In the early seventh century, Brahmagupta described ten types of instruments, which were adopted by all subsequent writers with minor modifications. Contact with Islamic astronomy in the second millennium AD led to a radical change. Sanskrit texts began to lay emphasis on the importance of observational instruments. Exclusive texts on instruments were composed. Islamic instruments like the astrolabe were adopted and some new types of instruments were developed. Production and use of these traditional instruments continued, along with the cultivation of traditional astronomy, up to the end of the nineteenth century.

  18. Mars Miniature Science Instruments

    NASA Technical Reports Server (NTRS)

    Kim, Soon Sam; Hayati, Samad; Lavery, David; McBrid, Karen

    2006-01-01

    For robotic Mars missions, all the science information is gathered through on-board miniature instruments that have been developed through many years of R&D. Compared to laboratory counterparts, the rover instruments require miniaturization, such as low mass (1-2 kg), low power (> 10 W) and compact (1-2 liter), yet with comparable sensitivity. Since early 1990's, NASA recognized the need for the miniature instruments and launched several instrument R&D programs, e.g., PIDDP (Planetary Instrument Definition and Development). However, until 1998, most of the instrument R&D programs supported only up to a breadboard level (TRL 3, 4) and there is a need to carry such instruments to flight qualifiable status (TU 5, 6) to respond to flight AOs (Announcement of Opportunity). Most of flight AOs have only limited time and financial resources, and can not afford such instrument development processes. To bridge the gap between instrument R&D programs and the flight instrument needs, NASA's Mars Technology Program (MTP) created advanced instrumentation program, Mars Instrument Development Project (MIDP). MIDP candidate instruments are selected through NASA Research Announcement (NRA) process [l]. For example, MIDP 161998-2000) selected and developed 10 instruments, MIDP II (2003-2005) 16 instruments, and MIDP III (2004-2006) II instruments.Working with PIs, JPL has been managing the MIDP tasks since September 1998. All the instruments being developed under MIDP have been selected through a highly competitive NRA process, and employ state-of-the-art technology. So far, four MIDP funded instruments have been selected by two Mars missions (these instruments have further been discussed in this paper).

  19. Woodwind Instrument Maintenance.

    ERIC Educational Resources Information Center

    Sperl, Gary

    1980-01-01

    The author presents a simple maintenance program for woodwind instruments which includes the care of tendon corks, the need for oiling keys, and methods of preventing cracks in woodwind instruments. (KC)

  20. Regional Instrumentation Centers.

    ERIC Educational Resources Information Center

    Cromie, William J.

    1980-01-01

    Focuses on the activities of regional instrumentation centers that utilize the state-of-the-art instruments and methodology in basic scientific research. The emphasis is on the centers involved in mass spectroscopy, magnetic resonance spectroscopy, lasers, and accelerators. (SA)

  1. Instrument Modeling and Synthesis

    NASA Astrophysics Data System (ADS)

    Horner, Andrew B.; Beauchamp, James W.

    During the 1970s and 1980s, before synthesizers based on direct sampling of musical sounds became popular, replicating musical instruments using frequency modulation (FM) or wavetable synthesis was one of the “holy grails” of music synthesis. Synthesizers such as the Yamaha DX7 allowed users great flexibility in mixing and matching sounds, but were notoriously difficult to coerce into producing sounds like those of a given instrument. Instrument design wizards practiced the mysteries of FM instrument design.

  2. Computers in Scientific Instrumentation.

    ERIC Educational Resources Information Center

    Enke, C. G.

    1982-01-01

    Computer applications in scientific instrumentation are traced from early data processing to modern computer-based instruments. Probable pathways toward instruments with increased "intelligence" include, among others, implementation of hierarchical computer networks and microprocessor controllers and the simplification of programing. The…

  3. The Instrumental Model

    ERIC Educational Resources Information Center

    Yeates, Devin Rodney

    2011-01-01

    The goal of this dissertation is to enable better predictive models by engaging raw experimental data through the Instrumental Model. The Instrumental Model captures the protocols and procedures of experimental data analysis. The approach is formalized by encoding the Instrumental Model in an XML record. Decoupling the raw experimental data from…

  4. The Homologue of het-c of Neurospora crassa Lacks Vegetative Compatibility Function in Fusarium proliferatum†

    PubMed Central

    Kerényi, Zoltán; Oláh, Brigitta; Jeney, Apor; Hornok, László; Leslie, John F.

    2006-01-01

    For two fungal strains to be vegetatively compatible and capable of forming a stable vegetative heterokaryon they must carry matching alleles at a series of loci variously termed het or vic genes. Cloned het/vic genes from Neurospora crassa and Podospora anserina have no obvious functional similarity and have various cellular functions. Our objective was to identify the homologue of the Neurospora het-c gene in Fusarium proliferatum and to determine if this gene has a vegetative compatibility function in this economically important and widely dispersed fungal pathogen. In F. proliferatum and five other closely related Fusarium species we found a few differences in the DNA sequence, but the changes were silent and did not alter the amino acid sequence of the resulting protein. Deleting the gene altered sexual fertility as the female parent, but it did not alter male fertility or existing vegetative compatibility interactions. Replacement of the allele-specific portion of the coding sequence with the sequence of an alternate allele in N. crassa did not result in a vegetative incompatibility response in transformed strains of F. proliferatum. Thus, the fphch gene in Fusarium appears unlikely to have the vegetative compatibility function associated with its homologue in N. crassa. These results suggest that the vegetative compatibility phenotype may result from convergent evolution. Thus, the genes involved in this process may need to be identified at the species level or at the level of a group of species and could prove to be attractive targets for the development of antifungal agents. PMID:17021201

  5. High temperature geophysical instrumentation

    SciTech Connect

    Hardee, H.C.

    1988-06-01

    The instrumentation development program was to proceed in parallel with scientific research and was driven by the needs of researchers. The development of these instruments has therefore included numerous geophysical field tests, many of which have resulted in the publication of scientific articles. This paper is a brief summary of some of the major geophysical instruments that have been developed and tested under the High Temperature Geophysics Program. These instruments are briefly described and references are given for further detailed information and for scientific papers that have resulted from the use of these instruments. 9 refs., 14 figs.

  6. Seismic instrumentation of buildings

    USGS Publications Warehouse

    Çelebi, Mehmet

    2000-01-01

    The purpose of this report is to provide information on how and why we deploy seismic instruments in and around building structures. The recorded response data from buildings and other instrumented structures can be and are being primarily used to facilitate necessary studies to improve building codes and therefore reduce losses of life and property during damaging earthquakes. Other uses of such data can be in emergency response situations in large urban environments. The report discusses typical instrumentation schemes, existing instrumentation programs, the steps generally followed in instrumenting a structure, selection and type of instruments, installation and maintenance requirements and data retrieval and processing issues. In addition, a summary section on how recorded response data have been utilized is included. The benefits from instrumentation of structural systems are discussed.

  7. Present status of aircraft instruments

    NASA Technical Reports Server (NTRS)

    1932-01-01

    This report gives a brief description of the present state of development and of the performance characteristics of instruments included in the following group: speed instruments, altitude instruments, navigation instruments, power-plant instruments, oxygen instruments, instruments for aerial photography, fog-flying instruments, general problems, summary of instrument and research problems. The items considered under performance include sensitivity, scale errors, effects of temperature and pressure, effects of acceleration and vibration, time lag, damping, leaks, elastic defects, and friction.

  8. VIRUS instrument enclosures

    NASA Astrophysics Data System (ADS)

    Prochaska, T.; Allen, R.; Mondrik, N.; Rheault, J. P.; Sauseda, M.; Boster, E.; James, M.; Rodriguez-Patino, M.; Torres, G.; Ham, J.; Cook, E.; Baker, D.; DePoy, Darren L.; Marshall, Jennifer L.; Hill, G. J.; Perry, D.; Savage, R. D.; Good, J. M.; Vattiat, Brian L.

    2014-08-01

    The Visible Integral-Field Replicable Unit Spectrograph (VIRUS) instrument will be installed at the Hobby-Eberly Telescope† in the near future. The instrument will be housed in two enclosures that are mounted adjacent to the telescope, via the VIRUS Support Structure (VSS). We have designed the enclosures to support and protect the instrument, to enable servicing of the instrument, and to cool the instrument appropriately while not adversely affecting the dome environment. The system uses simple HVAC air handling techniques in conjunction with thermoelectric and standard glycol heat exchangers to provide efficient heat removal. The enclosures also provide power and data transfer to and from each VIRUS unit, liquid nitrogen cooling to the detectors, and environmental monitoring of the instrument and dome environments. In this paper, we describe the design and fabrication of the VIRUS enclosures and their subsystems.

  9. Wet chemistry instrument prototype

    NASA Technical Reports Server (NTRS)

    1974-01-01

    A wet chemistry instrument prototype for detecting amino acids in planetary soil samples was developed. The importance of amino acids and their condensation products to the development of life forms is explained. The characteristics of the instrument and the tests which were conducted to determine the materials compatibility are described. Diagrams are provided to show the construction of the instrument. Data obtained from the performance tests are reported.

  10. Instrument validation project

    SciTech Connect

    Reynolds, B.A.; Daymo, E.A.; Geeting, J.G.H.; Zhang, J.

    1996-06-01

    Westinghouse Hanford Company Project W-211 is responsible for providing the system capabilities to remove radioactive waste from ten double-shell tanks used to store radioactive wastes on the Hanford Site in Richland, Washington. The project is also responsible for measuring tank waste slurry properties prior to injection into pipeline systems, including the Replacement of Cross-Site Transfer System. This report summarizes studies of the appropriateness of the instrumentation specified for use in Project W-211. The instruments were evaluated in a test loop with simulated slurries that covered the range of properties specified in the functional design criteria. The results of the study indicate that the compact nature of the baseline Project W-211 loop does not result in reduced instrumental accuracy resulting from poor flow profile development. Of the baseline instrumentation, the Micromotion densimeter, the Moore Industries thermocouple, the Fischer and Porter magnetic flow meter, and the Red Valve Pressure transducer meet the desired instrumental accuracy. An alternate magnetic flow meter (Yokagawa) gave nearly identical results as the baseline fischer and Porter. The Micromotion flow meter did not meet the desired instrument accuracy but could potentially be calibrated so that it would meet the criteria. The Nametre on-line viscometer did not meet the desired instrumental accuracy and is not recommended as a quantitative instrument although it does provide qualitative information. The recommended minimum set of instrumentation necessary to ensure the slurry meets the Project W-058 acceptance criteria is the Micromotion mass flow meter and delta pressure cells.

  11. Instrument performance evaluation

    SciTech Connect

    Swinth, K.L.

    1993-03-01

    Deficiencies exist in both the performance and the quality of health physics instruments. Recognizing the implications of such deficiencies for the protection of workers and the public, in the early 1980s the DOE and the NRC encouraged the development of a performance standard and established a program to test a series of instruments against criteria in the standard. The purpose of the testing was to establish the practicality of the criteria in the standard, to determine the performance of a cross section of available instruments, and to establish a testing capability. Over 100 instruments were tested, resulting in a practical standard and an understanding of the deficiencies in available instruments. In parallel with the instrument testing, a value-impact study clearly established the benefits of implementing a formal testing program. An ad hoc committee also met several times to establish recommendations for the voluntary implementation of a testing program based on the studies and the performance standard. For several reasons, a formal program did not materialize. Ongoing tests and studies have supported the development of specific instruments and have helped specific clients understand the performance of their instruments. The purpose of this presentation is to trace the history of instrument testing to date and suggest the benefits of a centralized formal program.

  12. DRAMA: Instrumentation software environment

    NASA Astrophysics Data System (ADS)

    Bailey, Jeremy; Shortridge, Keith; Farrell, Tony

    2015-07-01

    DRAMA is a fast, distributed environment for writing instrumentation control systems. It allows low level instrumentation software to be controlled from user interfaces running on UNIX, MS Windows or VMS machines in a consistent manner. Such instrumentation tasks can run either on these machines or on real time systems such as VxWorks. DRAMA uses techniques developed by the AAO while using the Starlink-ADAM environment, but is optimized for the requirements of instrumentation control, portability, embedded systems and speed. A special program is provided which allows seamless communication between ADAM and DRAMA tasks.

  13. Space applications instrumentation systems

    NASA Technical Reports Server (NTRS)

    Minzner, R. A.; Oberholtzer, J. D.

    1972-01-01

    A compendium of resumes of 158 instrument systems or experiments, of particular interest to space applications, is presented. Each resume exists in a standardized format, permitting entries for 26 administrative items and 39 scientific or engineering items. The resumes are organized into forty groups determined by the forty spacecraft with which the instruments are associated. The resumes are followed by six different cross indexes, each organized alphabetically according to one of the following catagories: instrument name, acronym, name of principal investigator, name of organization employing the principal investigator, assigned experiment number, and spacecraft name. The resumes are associated with a computerized instrument resume search and retrieval system.

  14. The RGSGR amino acid motif of the intercellular signalling protein, HetN, is required for patterning of heterocysts in Anabaena sp. strain PCC 7120.

    PubMed

    Higa, Kelly C; Rajagopalan, Ramya; Risser, Douglas D; Rivers, Orion S; Tom, Sasa K; Videau, Patrick; Callahan, Sean M

    2012-02-01

    Nitrogen-fixing heterocysts are arranged in a periodic pattern on filaments of the cyanobacterium Anabaena sp. strain PCC 7120 under conditions of limiting combined nitrogen. Patterning requires two inhibitors of heterocyst differentiation, PatS and HetN, which work at different stages of differentiation by laterally suppressing levels of an activator of differentiation, HetR, in cells adjacent to source cells. Here we show that the RGSGR sequence in the 287-amino-acid HetN protein, which is shared by PatS, is critical for patterning. Conservative substitutions in any of the five amino acids lowered the extent to which HetN inhibited differentiation when overproduced and altered the pattern of heterocysts in filaments with an otherwise wild-type genetic background. Conversely, substitution of amino acids comprising the putative catalytic triad of this predicted reductase had no effect on inhibition or patterning. Deletion of putative domains of HetN suggested that the RGSGR motif is the primary component of HetN required for both its inhibitory and patterning activity, and that localization to the cell envelope is not required for patterning of heterocysts. The intercellular signalling proteins PatS and HetN use the same amino acid motif to regulate different stages of heterocyst patterning.

  15. A new control system hardware architecture for the Hobby-Eberly Telescope prime focus instrument package

    NASA Astrophysics Data System (ADS)

    Ramiller, Chuck; Taylor, Trey; Rafferty, Tom H.; Cornell, Mark E.; Rafal, Marc; Savage, Richard

    2010-07-01

    The Hobby-Eberly Telescope (HET) will be undergoing a major upgrade as a precursor to the HET Dark Energy Experiment (HETDEX‡). As part of this upgrade, the Prime Focus Instrument Package (PFIP) will be replaced with a new design that supports the HETDEX requirements along with the existing suite of instruments and anticipated future additions. This paper describes the new PFIP control system hardware plus the physical constraints and other considerations driving its design. Because of its location at the top end of the telescope, the new PFIP is essentially a stand-alone remote automation island containing over a dozen subsystems. Within the PFIP, motion controllers and modular IO systems are interconnected using a local Controller Area Network (CAN) bus and the CANOpen messaging protocol. CCD cameras that are equipped only with USB 2.0 interfaces are connected to a local Ethernet network via small microcontroller boards running embedded Linux. Links to ground-level systems pass through a 100 m cable bundle and use Ethernet over fiber optic cable exclusively; communications are either direct or through Ethernet/CAN gateways that pass CANOpen messages transparently. All of the control system hardware components are commercially available, designed for rugged industrial applications, and rated for extended temperature operation down to -10 °C.

  16. Experience with the HET-CAM method in the routine testing of a broad variety of chemicals and formulations.

    PubMed

    Schrage, Arnhild; Gamer, Armin O; van Ravenzwaay, Ben; Landsiedel, Robert

    2010-03-01

    Data on eye irritation are generally needed for the hazard identification of chemicals. For the routine testing of a broad variety of chemicals and formulations, we have used the Hen's Egg Test-Chorioallantoic Membrane (HET-CAM) method. In the course of a tiered-testing strategy, and due to the lack of global regulatory acceptance of the HET-CAM method, we have also performed the Rabbit Eye Irritation test according to OECD Test Guideline 405. Of the 145 substances tested, 76% were classified as non-irritant/mild irritant and 13% were identified as irritant in vivo, according to the EU classification system (61% and 28%, respectively, with the GHS classification). The remaining 11% were severe irritants in vivo, based on the irreversibility of the effects and not due to sufficiently high irritation scores in the three days following application. The retrospective analysis revealed that the overall accuracy of the HET-CAM assay was 65% and the overall rates of false-negatives (FN) and false-positives (FP) were 50% and 33%, respectively. The HET-CAM assay was sufficiently specific (few FP) for water-soluble substances, but failed to identify nearly all the severe irritants within this group. In contrast, it was highly sensitive (no FN) for non-soluble and oil-soluble substances, but the specificity for this group was rather low. Therefore, we conclude that the HET-CAM assay is not useful in our tiered-testing strategy for eye irritation testing. However, for water-insoluble substances, it might be applicable in combination with another in vitro method, provided that regulatory acceptance is gained.

  17. BAA instrument no. 93

    NASA Astrophysics Data System (ADS)

    Marriott, R. A.

    2006-12-01

    Instrument no. 93 has been in almost continual use for more than a hundred years. Since it left the workshop of its maker, George Calver, it has kept company with several other notable instruments and has been used by many eminent astronomers. It was added to the Association's collection in 1945.

  18. Topics in Chemical Instrumentation

    ERIC Educational Resources Information Center

    Ewing, Galen W., Ed.

    1975-01-01

    Identifies a trend in analytical chemistry toward greater use of instruments and a need for an understanding of the basic principles involved in instrumentation. This need can be fulfilled using homebuilt equipment; examples are provided in the areas of electrolytic conductance and electronic coulometry. (GS)

  19. Clinical immunoassay instrument markets

    SciTech Connect

    Not Available

    1984-11-01

    The present status and future prospects of the market for clinical immunoassay instruments is discussed. The market shares for the five basic instrument types - nephelometric immunoassay, fluorescence immmunoassay, enzyme immunoassay, luminescence immunoassay, and radioimmunoassay are presented. It is noted that radioimmunoassay hold a major, but decreasing, share of the market.

  20. Affective Involvement Instrument.

    ERIC Educational Resources Information Center

    Lemlech, Johanna K.

    1970-01-01

    The Affective Involvement Instrument (AII) describes and classifies affective involvement in the process of decision-making as it occurs during classroom activities such as role-playing or group discussions. The thirty-celled instrument behaviorizes the six processes involved in decision-making and combines them with the taxonomic levels of the…

  1. Aeronautic Instruments. Section II : Altitude Instruments

    NASA Technical Reports Server (NTRS)

    Mears, A H; Henrickson, H B; Brombacher, W G

    1923-01-01

    This report is Section two of a series of reports on aeronautic instruments (Technical Report nos. 125 to 132, inclusive). This section discusses briefly barometric altitude determinations, and describes in detail the principal types of altimeters and barographs used in aeronautics during the recent war. This is followed by a discussion of performance requirements for such instruments and an account of the methods of testing developed by the Bureau of Standards. The report concludes with a brief account of the results of recent investigations. For accurate measurements of altitude, reference must also be made to thermometer readings of atmospheric temperature, since the altitude is not fixed by atmospheric pressure alone. This matter is discussed in connection with barometric altitude determination.

  2. High Efficiency Thermionics (HET-IV) and Converter Advancement (CAP) programs. Final reports

    SciTech Connect

    Geller, C.B.; Murray, C.S.; Riley, D.R.; Desplat, J.L.; Hansen, L.K.; Hatch, G.L.; McVey, J.B.; Rasor, N.S.

    1996-04-01

    This report contains the final report of the High Efficiency Thermionics (HET-IV) Program, Attachment A, performed at Rasor Associates, Inc. (RAI); and the final report of the Converter Advancement Program (CAP), performed at the Bettis Atomic Power Laboratory, Attachment B. The phenomenology of cesium-oxygen thermionic converters was elucidated in these programs, and the factors that had prevented the achievement of stable, enhanced cesium-oxygen converter performance for the previous thirty years were identified. Based on these discoveries, cesium-oxygen vapor sources were developed that achieved stable performance with factor-of-two improvements in power density and thermal efficiency, relative to conventional, cesium-only ignited mode thermionic converters. Key achievements of the HET-IV/CAP programs are as follows: a new technique for measuring minute traces of oxygen in cesium atmospheres; the determination of the proper range of oxygen partial pressures for optimum converter performance--10{sup {minus}7} to 10{sup {minus}9} torr; the discovery, and analysis of the cesium-oxygen liquid migration and compositional segregation phenomena; the successful use of capillary forces to contain the migration phenomenon; the use of differential heating to control compositional segregation, and induce vapor circulation; the development of mechanically and chemically stable, porous reservoir structures; the development of precise, in situ oxygen charging methods; stable improvements in emitter performance, up to effective emitter bare work functions of 5.4 eV; stable improvements in barrier index, to value below 1.8 Volts; the development of detailed microscopic models for cesium-oxygen reservoir dynamics and collector work function behavior; and the discovery of new relationships between electrode geometry and Schock Instability.

  3. The DKIST Instrumentation Suite

    NASA Astrophysics Data System (ADS)

    Woeger, Friedrich

    2016-05-01

    The Daniel K. Inouye Solar Telescope with its four meter diameter aperture will be the largest telescope in the world for solar observations when it is commissioned in the year 2019. In order to harness its scientific potential immediately, DKIST will integrate five instruments that each will provide unique functionality to measure properties of the solar atmosphere at unprecedented spatial resolution.In this paper we discuss the unique capabilities in the DKIST instrument suite that consists of the Visible Broadband Imager (VBI), the Visible Spectro-Polarimeter (ViSP), the Visible Tunable Filter (VTF), the Diffraction-Limited Near-Infrared Spectro-Polarimeter (DL-NIRSP), and the Cryogenic Near-Infrared Spectro-Polarimeter (Cryo-NIRSP).In addition, we will explain the facility's approach to supporting high spatial resolution data acquisition with multiple instruments simultaneously by means of the Facility Instrument Distribution Optics. This system of wavelength separating and interchangeable beamsplitters will enable a variety of different ways to optically configure the light beam to the instruments. This approach ensures that the DKIST instruments can use their individual advantages in a multitude of different observing scenarios. The DKIST instrumentation suite will enable crucial new insights into complex physical processes that occur on spatial scales that are smaller than any solar structure observed in the past.

  4. Remote instrument telemaintenance.

    PubMed

    Laugier, A; Allahwerdi, N; Baudin, J; Gaffney, P; Grimson, W; Groth, T; Schilders, L

    1996-07-01

    In the past decade, great technological progress has been made in telemaintenance of mainframe and mini computers. As hardware technology is now available at an acceptable cost, computer aided trouble-shooting can be adapted to laboratory instrumentation in order to significantly improve repair time, avoid instrument downtime by taking advantage of predictive methods, and provide general diagnostic assistance. Depending on the size of the instrument, the telemaintenance facility can be dedicated to a single instrument or alternatively a telemaintenance server can manage multiple distributed small instruments through a Local Area Network. As complex failures can occur, the local diagnosis capabilities may be exceeded and automatic dialing for connection to computerized Remote Maintenance Centers is needed. The main advantages of such a centre, as compared to local diagnosis systems, are the increased access to more information and experience of failures from instrument installations, and consequently the provision of training data updates for Artificial Neural Networks and Knowledge Based Systems in general. When an abnormal situation is detected or anticipated by a diagnosis module, an automatic alert is given to the user, local diagnosis is activated, and for simple solutions, instructions are given to the operator. In the last resort, a human expert can be alerted who, with remote control tools, can attend to the failures. For both local and remote trouble-shooting, the data provided by the instrument and connected workstation is of paramount importance for the efficiency and accuracy of the diagnosis. Equally, the importance of standardization of telemaintenance communication protocols is addressed.

  5. Mass spectrometers: instrumentation

    NASA Astrophysics Data System (ADS)

    Cooks, R. G.; Hoke, S. H., II; Morand, K. L.; Lammert, S. A.

    1992-09-01

    Developments in mass spectrometry instrumentation over the past three years are reviewed. The subject is characterized by an enormous diversity of designs, a high degree of competition between different laboratories working with either different or similar techniques and by extremely rapid progress in improving analytical performance. Instruments can be grouped into genealogical charts based on their physical and conceptual interrelationships. This is illustrated using mass analyzers of different types. The time course of development of particular instrumental concepts is illustrated in terms of the s-curves typical of cell growth. Examples are given of instruments which are at the exponential, linear and mature growth stages. The prime examples used are respectively: (i) hybrid instruments designed to study reactive collisions of ions with surfaces: (ii) the Paul ion trap; and (iii) the triple quadrupole mass spectrometer. In the area of ion/surface collisions, reactive collisions such as hydrogen radical abstraction from the surface by the impinging ion are studied. They are shown to depend upon the chemical nature of the surface through the use of experiments which utilize self-assembled monolayers as surfaces. The internal energy deposited during surface-induced dissociation upon collision with different surfaces in a BEEQ instrument is also discussed. Attention is also given to a second area of emerging instrumentation, namely technology which allows mass spectrometers to be used for on-line monitoring of fluid streams. A summary of recent improvements in the performance of the rapidly developing quadrupole ion trap instrument illustrates this stage of instrument development. Improvements in resolution and mass range and their application to the characterization of biomolecules are described. The interaction of theory with experiment is illustrated through the role of simulations of ion motion in the ion trap. It is emphasized that mature instruments play a

  6. Instrument Attitude Precision Control

    NASA Technical Reports Server (NTRS)

    Juang, Jer-Nan

    2004-01-01

    A novel approach is presented in this paper to analyze attitude precision and control for an instrument gimbaled to a spacecraft subject to an internal disturbance caused by a moving component inside the instrument. Nonlinear differential equations of motion for some sample cases are derived and solved analytically to gain insight into the influence of the disturbance on the attitude pointing error. A simple control law is developed to eliminate the instrument pointing error caused by the internal disturbance. Several cases are presented to demonstrate and verify the concept presented in this paper.

  7. Aircraft Speed Instruments

    NASA Technical Reports Server (NTRS)

    Beij, K Hilding

    1933-01-01

    This report presents a concise survey of the measurement of air speed and ground speed on board aircraft. Special attention is paid to the pitot-static air-speed meter which is the standard in the United States for airplanes. Air-speed meters of the rotating vane type are also discussed in considerable detail on account of their value as flight test instruments and as service instruments for airships. Methods of ground-speed measurement are treated briefly, with reference to the more important instruments. A bibliography on air-speed measurement concludes the report.

  8. Writing Instrument Profiles for Mastery of Instrumental Analysis

    ERIC Educational Resources Information Center

    King, Daniel; Fernandez, Jorge; Nalliah, Ruth

    2012-01-01

    Because of the rapidly changing nature of chemical instrumentation, students must be trained in how to learn and understand new instruments. Toward this end, students are asked to create small instrument manuals, or instrument profiles, for the major pieces of equipment studied during an instrumental analysis course. This writing-intensive process…

  9. Low cost instrumentation amplifier

    NASA Technical Reports Server (NTRS)

    Sturman, J. C.

    1974-01-01

    Amplifier can be used for many applications requiring high input impedance and common mode rejection, low drift, and gain accuracy on order of one percent. Performance of inexpensive amplifier approaches that of some commercial instrumentation amplifiers in many specifications.

  10. Cardiovascular instrumentation for spaceflight

    NASA Technical Reports Server (NTRS)

    Schappell, R. T.; Polhemus, J. T.; Ganiaris, N. J.

    1976-01-01

    The observation mechanisms dealing with pressure, flow, morphology, temperature, etc. are discussed. The approach taken in the performance of this study was to (1) review ground and space-flight data on cardiovascular function, including earlier related ground-based and space-flight animal studies, Mercury, Gemini, Apollo, Skylab, and recent bed-rest studies, (2) review cardiovascular measurement parameters required to assess individual performance and physiological alternations during space flight, (3) perform an instrumentation survey including a literature search as well as personal contact with the applicable investigators, (4) assess instrumentation applicability with respect to the established criteria, and (5) recommend future research and development activity. It is concluded that, for the most part, the required instrumentation technology is available but that mission-peculiar criteria will require modifications to adapt the applicable instrumentation to a space-flight configuration.

  11. Fiber Optics Instrumentation Development

    NASA Technical Reports Server (NTRS)

    Chan, Patrick Hon Man; Parker, Allen R., Jr.; Richards, W. Lance

    2010-01-01

    This is a general presentation of fiber optics instrumentation development work being conducted at NASA Dryden for the past 10 years and recent achievements in the field of fiber optics strain sensors.

  12. CALIPSO Instrument Operational

    Atmospheric Science Data Center

    2014-09-18

    CALIPSO Instrument Operational Thursday, September 11, 2014 The CALIPSO payload is back in data acquisition mode as of Wednesday, September 17, 2014.  CALIPSO data processing has returned to a nominal state, and...

  13. Instrumentation for Materials Research

    ERIC Educational Resources Information Center

    Claassen, Richard S.

    1976-01-01

    Discusses how sophisticated instrumentation techniques yield practical results in three typical materials problems: fracture analysis, joining, and compatibility. Describes techniques such as scanning and transmission electron microscopy, and Auger spectroscopy. (MLH)

  14. AIR Instrument Array

    NASA Technical Reports Server (NTRS)

    Jones, I. W.; Wilson, J. W.; Maiden, D. L.; Goldhagen, P.; Shinn, J. L.

    2003-01-01

    The large number of radiation types composing the atmospheric radiation requires a complicated combination of instrument types to fully characterize the environment. A completely satisfactory combination has not as yet been flown and would require a large capital outlay to develop. In that the funds of the current project were limited to essential integration costs, an international collaboration was formed with partners from six countries and fourteen different institutions with their own financial support for their participation. Instruments were chosen to cover sensitivity to all radiation types with enough differential sensitivity to separate individual components. Some instruments were chosen as important to specify the physical field component and other instruments were chosen on the basis that they could be useful in dosimetric evaluation. In the present paper we will discuss the final experimental flight package for the ER-2 flight campaign.

  15. NPP: The Five Instruments

    NASA Video Gallery

    The NPP satellite has 5 instruments on board: VIIRS, CERES, CrIS, ATMS, and OMPS. Each one will deliver a specific set of data helping weather prediction and climate studies. This video is a quick ...

  16. Aeronautic Instruments. Section III : Aircraft Speed Instruments

    NASA Technical Reports Server (NTRS)

    Hunt, Franklin L; Stearns, H O

    1923-01-01

    Part 1 contains a discussion and description of the various types of air speed measuring instruments. The authors then give general specifications and performance requirements with the results of tests on air speed indicators at the Bureau of Standards. Part 2 reports methods and laboratory apparatus used at the Bureau of Standards to make static tests. Methods are also given of combining wind tunnel tests with static tests. Consideration is also given to free flight tests. Part 3 discusses the problem of finding suitable methods for the purpose of measuring the speed of aircraft relative to the ground.

  17. VIRUS instrument collimator assembly

    NASA Astrophysics Data System (ADS)

    Marshall, Jennifer L.; DePoy, Darren L.; Prochaska, Travis; Allen, Richard D.; Williams, Patrick; Rheault, Jean-Philippe; Li, Ting; Nagasawa, Daniel Q.; Akers, Christopher; Baker, David; Boster, Emily; Campbell, Caitlin; Cook, Erika; Elder, Alison; Gary, Alex; Glover, Joseph; James, Michael; Martin, Emily; Meador, Will; Mondrik, Nicholas; Rodriguez-Patino, Marisela; Villanueva, Steven; Hill, Gary J.; Tuttle, Sarah; Vattiat, Brian; Lee, Hanshin; Chonis, Taylor S.; Dalton, Gavin B.; Tacon, Mike

    2014-07-01

    The Visual Integral-Field Replicable Unit Spectrograph (VIRUS) instrument is a baseline array 150 identical fiber fed optical spectrographs designed to support observations for the Hobby-Eberly Telescope Dark Energy Experiment (HETDEX). The collimator subassemblies of the instrument have been assembled in a production line and are now complete. Here we review the design choices and assembly practices used to produce a suite of identical low-cost spectrographs in a timely fashion using primarily unskilled labor.

  18. Modeling of Musical Instruments

    NASA Astrophysics Data System (ADS)

    Bader, Rolf; Hansen, Uwe

    Signal processing techniques in acoustics address many concerns. Included are such things as wave propagation variables, amplitude considerations, spectral content, wavelength, and phase. Phase is primarily of concern when waves interact with each other, as well as with a medium, and the imposition of boundary conditions leads to normal mode vibrations. Such conditions are prevalent in all musical instruments, and thus relevant signal processing techniques are essential to both understanding and modeling the structure of musical instruments and the sound radiated.

  19. Instrumentation in Arthroscopy.

    PubMed

    Barp, Eric A; Erickson, John G; Reese, Eric R

    2016-10-01

    In recent years, arthroscopic procedures of the foot and ankle have seen a significant increase in both indications and popularity. Furthermore, technological advances in video quality, fluid management, and other arthroscopy-specific instruments continue to make arthroscopic procedures more effective with reproducible outcomes. As surgeons continue to use this approach, it is important that they have a complete understanding of the instrumentation available to them, including their indications and limitations. PMID:27599434

  20. [The instrument for thermography].

    PubMed

    Hamaguchi, Shinsuke

    2014-07-01

    Thermography is an imaging method using the instrument to detect infrared rays emitted from the body surface, and to plot them as a distribution diagram of the temperature information. Therefore, a thermographic instrument can be assumed to measure the skin temperature of the diseased region. Such an instrument is a useful device for noninvasive and objective assessment of various diseases. Examination using a thermographic instrument can assess the autonomic dysfunction by measuring the skin blood flow involved with the sympathetic innervation. Thermography is useful in assisting the determination of the therapeutic effect. However, autonomic dysfunction should be confirmed correctly with the assessment of thermatome that shows abnormal thermal distribution in the region of the disease. Thermography should make noticeable the difference between the body temperature of abnormal and normal sites, and show the alteration of temperature. Monitoring using thermography is useful to determine the effect of sympathetic nerve block. If a thermographic instrument is used, it is important that examiners should understand the function of the instrument, as well as its advantages and disadvantages. PMID:25098130

  1. Advanced optical instruments technology

    NASA Technical Reports Server (NTRS)

    Shao, Mike; Chrisp, Michael; Cheng, Li-Jen; Eng, Sverre; Glavich, Thomas; Goad, Larry; Jones, Bill; Kaarat, Philip; Nein, Max; Robinson, William

    1992-01-01

    The science objectives for proposed NASA missions for the next decades push the state of the art in sensitivity and spatial resolution over a wide range of wavelengths, including the x-ray to the submillimeter. While some of the proposed missions are larger and more sensitive versions of familiar concepts, such as the next generation space telescope, others use concepts, common on the Earth, but new to space, such as optical interferometry, in order to provide spatial resolutions impossible with other concepts. However, despite their architecture, the performance of all of the proposed missions depends critically on the back-end instruments that process the collected energy to produce scientifically interesting outputs. The Advanced Optical Instruments Technology panel was chartered with defining technology development plans that would best improve optical instrument performance for future astrophysics missions. At this workshop the optical instrument was defined as the set of optical components that reimage the light from the telescope onto the detectors to provide information about the spatial, spectral, and polarization properties of the light. This definition was used to distinguish the optical instrument technology issues from those associated with the telescope, which were covered by a separate panel. The panel identified several areas for optical component technology development: diffraction gratings; tunable filters; interferometric beam combiners; optical materials; and fiber optics. The panel also determined that stray light suppression instruments, such as coronagraphs and nulling interferometers, were in need of general development to support future astrophysics needs.

  2. Medical instrument data exchange.

    PubMed

    Gumudavelli, Suman; McKneely, Paul K; Thongpithoonrat, Pongnarin; Gurkan, D; Chapman, Frank M

    2008-01-01

    Advances in medical devices and health care has been phenomenal during the recent years. Although medical device manufacturers have been improving their instruments, network connection of these instruments still rely on proprietary technologies. Even if the interface has been provided by the manufacturer (e.g., RS-232, USB, or Ethernet coupled with a proprietary API), there is no widely-accepted uniform data model to access data of various bedside instruments. There is a need for a common standard which allows for internetworking with the medical devices from different manufacturers. ISO/IEEE 11073 (X73) is a standard attempting to unify the interfaces of all medical devices. X73 defines a client access mechanism that would be implemented into the communication controllers (residing between an instrument and the network) in order to access/network patient data. On the other hand, MediCAN technology suite has been demonstrated with various medical instruments to achieve interfacing and networking with a similar goal in its open standardization approach. However, it provides a more generic definition for medical data to achieve flexibility for networking and client access mechanisms. In this paper, a comparison between the data model of X73 and MediCAN will be presented to encourage interoperability demonstrations of medical instruments. PMID:19163033

  3. Subcellular Localization and Clues for the Function of the HetN Factor Influencing Heterocyst Distribution in Anabaena sp. Strain PCC 7120

    PubMed Central

    Corrales-Guerrero, Laura; Mariscal, Vicente; Nürnberg, Dennis J.; Elhai, Jeff; Mullineaux, Conrad W.; Flores, Enrique

    2014-01-01

    In the filamentous cyanobacterium Anabaena sp. strain PCC 7120, heterocysts are formed in the absence of combined nitrogen, following a specific distribution pattern along the filament. The PatS and HetN factors contribute to the heterocyst pattern by inhibiting the formation of consecutive heterocysts. Thus, inactivation of any of these factors produces the multiple contiguous heterocyst (Mch) phenotype. Upon N stepdown, a HetN protein with its C terminus fused to a superfolder version of green fluorescent protein (sf-GFP) or to GFP-mut2 was observed, localized first throughout the whole area of differentiating cells and later specifically on the peripheries and in the polar regions of mature heterocysts, coinciding with the location of the thylakoids. Polar localization required an N-terminal stretch comprising residues 2 to 27 that may represent an unconventional signal peptide. Anabaena strains expressing a version of HetN lacking this fragment from a mutant gene placed at the native hetN locus exhibited a mild Mch phenotype. In agreement with previous results, deletion of an internal ERGSGR sequence, which is identical to the C-terminal sequence of PatS, also led to the Mch phenotype. The subcellular localization in heterocysts of fluorescence resulting from the fusion of GFP to the C terminus of HetN suggests that a full HetN protein is present in these cells. Furthermore, the full HetN protein is more conserved among cyanobacteria than the internal ERGSGR sequence. These observations suggest that HetN anchored to thylakoid membranes in heterocysts may serve a function besides that of generating a regulatory (ERGSGR) peptide. PMID:25049089

  4. Subcellular localization and clues for the function of the HetN factor influencing heterocyst distribution in Anabaena sp. strain PCC 7120.

    PubMed

    Corrales-Guerrero, Laura; Mariscal, Vicente; Nürnberg, Dennis J; Elhai, Jeff; Mullineaux, Conrad W; Flores, Enrique; Herrero, Antonia

    2014-10-01

    In the filamentous cyanobacterium Anabaena sp. strain PCC 7120, heterocysts are formed in the absence of combined nitrogen, following a specific distribution pattern along the filament. The PatS and HetN factors contribute to the heterocyst pattern by inhibiting the formation of consecutive heterocysts. Thus, inactivation of any of these factors produces the multiple contiguous heterocyst (Mch) phenotype. Upon N stepdown, a HetN protein with its C terminus fused to a superfolder version of green fluorescent protein (sf-GFP) or to GFP-mut2 was observed, localized first throughout the whole area of differentiating cells and later specifically on the peripheries and in the polar regions of mature heterocysts, coinciding with the location of the thylakoids. Polar localization required an N-terminal stretch comprising residues 2 to 27 that may represent an unconventional signal peptide. Anabaena strains expressing a version of HetN lacking this fragment from a mutant gene placed at the native hetN locus exhibited a mild Mch phenotype. In agreement with previous results, deletion of an internal ERGSGR sequence, which is identical to the C-terminal sequence of PatS, also led to the Mch phenotype. The subcellular localization in heterocysts of fluorescence resulting from the fusion of GFP to the C terminus of HetN suggests that a full HetN protein is present in these cells. Furthermore, the full HetN protein is more conserved among cyanobacteria than the internal ERGSGR sequence. These observations suggest that HetN anchored to thylakoid membranes in heterocysts may serve a function besides that of generating a regulatory (ERGSGR) peptide.

  5. Subcellular localization and clues for the function of the HetN factor influencing heterocyst distribution in Anabaena sp. strain PCC 7120.

    PubMed

    Corrales-Guerrero, Laura; Mariscal, Vicente; Nürnberg, Dennis J; Elhai, Jeff; Mullineaux, Conrad W; Flores, Enrique; Herrero, Antonia

    2014-10-01

    In the filamentous cyanobacterium Anabaena sp. strain PCC 7120, heterocysts are formed in the absence of combined nitrogen, following a specific distribution pattern along the filament. The PatS and HetN factors contribute to the heterocyst pattern by inhibiting the formation of consecutive heterocysts. Thus, inactivation of any of these factors produces the multiple contiguous heterocyst (Mch) phenotype. Upon N stepdown, a HetN protein with its C terminus fused to a superfolder version of green fluorescent protein (sf-GFP) or to GFP-mut2 was observed, localized first throughout the whole area of differentiating cells and later specifically on the peripheries and in the polar regions of mature heterocysts, coinciding with the location of the thylakoids. Polar localization required an N-terminal stretch comprising residues 2 to 27 that may represent an unconventional signal peptide. Anabaena strains expressing a version of HetN lacking this fragment from a mutant gene placed at the native hetN locus exhibited a mild Mch phenotype. In agreement with previous results, deletion of an internal ERGSGR sequence, which is identical to the C-terminal sequence of PatS, also led to the Mch phenotype. The subcellular localization in heterocysts of fluorescence resulting from the fusion of GFP to the C terminus of HetN suggests that a full HetN protein is present in these cells. Furthermore, the full HetN protein is more conserved among cyanobacteria than the internal ERGSGR sequence. These observations suggest that HetN anchored to thylakoid membranes in heterocysts may serve a function besides that of generating a regulatory (ERGSGR) peptide. PMID:25049089

  6. Aeronautic Instruments. Section V : Power Plant Instruments

    NASA Technical Reports Server (NTRS)

    Washburn, G E; Sylvander, R C; Mueller, E F; Wilhelm, R M; Eaton, H N; Warner, John A C

    1923-01-01

    Part 1 gives a general discussion of the uses, principles, construction, and operation of airplane tachometers. Detailed description of all available instruments, both foreign and domestic, are given. Part 2 describes methods of tests and effect of various conditions encountered in airplane flight such as change of temperature, vibration, tilting, and reduced air pressure. Part 3 describes the principal types of distance reading thermometers for aircraft engines, including an explanation of the physical principles involved in the functioning of the instruments and proper filling of the bulbs. Performance requirements and testing methods are given and a discussion of the source of error and results of tests. Part 4 gives methods of tests and calibration, also requirements of gauges of this type for the pressure measurement of the air pressure in gasoline tanks and the engine oil pressure on airplanes. Part 5 describes two types of gasoline gauges, the float type and the pressure type. Methods of testing and calibrating gasoline depth gauges are given. The Schroeder, R. A. E., and the Mark II flowmeters are described.

  7. Issues in Shuttle System Instrumentation

    NASA Technical Reports Server (NTRS)

    James, George

    2004-01-01

    The purose: a) Customer's perspective on Space Shuttle Return to Flight instrumentation; b) Focus on the difficult instrumentation issues; and c) Enable a discussion of new technologies (i.e.- NANO/MEMS/Small Tech) that could enhance Shuttle instrumentation posture. The T-10 Umbilical allows the vehicle instruments to be monitored and recorded prior to each launch and retract during launch.Launch Complex Instrumentation are instruments needed for assessment of Launch Commit Criteria (LCC) Salt-air and launch environments are issues. Instrumentation (Drag-On Instrumentation) can be added as needed to the vehicle for non-flight use. The current Roll-out Fatigue Testing is a primary example.

  8. Gamow-Teller unit cross sections for (t,{sup 3}He) and ({sup 3}He,t) reactions

    SciTech Connect

    Perdikakis, G.; Austin, Sam M.; Galaviz, D.; Tur, C.; Zegers, R. G. T.; Deaven, J. M.; Guess, C. J.; Hitt, G. W.; Meharchand, R.; Bazin, D.; Grinyer, G. F.; Caesar, C.; Herlitzius, C.; Gade, A.; Howard, M. E.; Smith, E. E.; Noji, S.; Sakai, H.; Shimbara, Y.

    2011-05-15

    The proportionality between differential cross sections at vanishing linear momentum transfer and Gamow-Teller transition strength, expressed in terms of the unit cross section ({sigma}{sub GT}), was studied as a function of target mass number for (t,{sup 3}He) and ({sup 3}He,t) reactions at 115A MeV and 140A MeV, respectively. Existing ({sup 3}He,t) and (t,{sup 3}He) data on targets with mass number 12{<=}A{<=}120 were complemented with new and reevaluated (t,{sup 3}He) data on proton, deuteron, {sup 6}Li, and {sup 12}C targets. It was found that in spite of the small difference in beam energies between the two probes, the unit cross sections have a nearly identical and simple dependence on target mass number A, for A{>=}12: {sigma}{sub GT}=109/A{sup 0.65}. The factorization of the unit cross sections in terms of a kinematical factor, a distortion factor, and the strength of the effective spin-isospin transfer nucleus-nucleus interaction was investigated. Simple phenomenological functions depending on mass number A were extracted for the latter two. By comparison with plane and distorted-wave Born approximation calculations, it was found that the use of a short-range approximation for knock-on exchange contributions to the transition amplitude results in overestimated cross sections for reactions involving the composite ({sup 3}He,t) and (t,{sup 3}He) probes.

  9. Preparation, characterization and structure determination of CpFe(CO)(EPh3)SeCO-het complexes

    NASA Astrophysics Data System (ADS)

    El-khateeb, Mohammad

    2016-11-01

    The mixed CO/ER3 iron complexes bearing heterocyclic selenocarboxylato group CpFe(CO)(ER3)SeCO-het [het = 2-C4H3S (1), 2-C4H3O (2), sbnd CH2-2-C4H3S (3), E = P, R = Ph (a), OC2H5 (b); E = As (c), Sb (d), R = Ph)] are synthesized by the reactions of CpFe(CO)2SeCO-het with ER3 under photolytic conditions. The new complexes have been characterized by spectroscopic analysis (UV-Vis, IR, 1H, 31P NMR) and elemental analysis. The structures of CpFe(CO)(PPh3)SeCO-2-C4H3S (1a), CpFe(CO)(AsPh3)SeCO-2-C4H3S (1c) and CpFe(CO)(SbPh3)SeCO-2-C4H3S (1d) have been determined by X-ray crystal structure analysis.

  10. Nonmetallic Diaphragms for Instruments

    NASA Technical Reports Server (NTRS)

    Eaton, H N; Buckingham, C T

    1925-01-01

    This report, the second of a series of reports relating to the general subject of instrument diaphragms. The first report of the series was published as Technical Report no. 165, "diaphragms for aeronautic instruments," and comprised an outline of historical developments and theoretical principles. The present report relates entirely to nonmetallic diaphragms, the use of which in certain types of pressure elements has been increasing for some time. Little, if any, information has been available to aid the designer of instruments using this form of pressure element. It was to attempt to meet the need for such information that the investigation reported in this paper was undertaken. The report describes the various materials which have been used as nonmetallic diaphragms, discusses the factors which affect the performance of the diaphragms and gives the results of tests made for the purpose of investigating the effect produced by these factors.

  11. Instrumentation at Gemini Observatory

    NASA Astrophysics Data System (ADS)

    Kleinman, S. J.; Boccas, Maxime; Goodsell, Stephen J.; Gomez, Percy; Murowinski, Rick; Chené, André-Nicolas; Henderson, David

    2014-07-01

    Gemini South's instrument suite has been completely transformed since our last biennial update. We commissioned the Gemini Multi-Conjugate Adaptive Optics System (GeMS) and its associated Gemini South Adaptive Optics Imager (GSAOI) as well as Flamingos-2, our long-slit and multi-object infrared imager and spectrograph, and the Gemini Planet Imager (GPI). We upgraded the CCDs in GMOS-S, our multi-object optical imager and spectrograph, with the GMOS-N CCD upgrade scheduled for 2015. Our next instrument, the Gemini High-resolution Optical SpecTrograph (GHOST) is in its preliminary design stage and we are making plans for the instrument to follow:Gen4#3.

  12. Virtual Sensor Test Instrumentation

    NASA Technical Reports Server (NTRS)

    Wang, Roy

    2011-01-01

    Virtual Sensor Test Instrumentation is based on the concept of smart sensor technology for testing with intelligence needed to perform sell-diagnosis of health, and to participate in a hierarchy of health determination at sensor, process, and system levels. A virtual sensor test instrumentation consists of five elements: (1) a common sensor interface, (2) microprocessor, (3) wireless interface, (4) signal conditioning and ADC/DAC (analog-to-digital conversion/ digital-to-analog conversion), and (5) onboard EEPROM (electrically erasable programmable read-only memory) for metadata storage and executable software to create powerful, scalable, reconfigurable, and reliable embedded and distributed test instruments. In order to maximize the efficient data conversion through the smart sensor node, plug-and-play functionality is required to interface with traditional sensors to enhance their identity and capabilities for data processing and communications. Virtual sensor test instrumentation can be accessible wirelessly via a Network Capable Application Processor (NCAP) or a Smart Transducer Interlace Module (STIM) that may be managed under real-time rule engines for mission-critical applications. The transducer senses the physical quantity being measured and converts it into an electrical signal. The signal is fed to an A/D converter, and is ready for use by the processor to execute functional transformation based on the sensor characteristics stored in a Transducer Electronic Data Sheet (TEDS). Virtual sensor test instrumentation is built upon an open-system architecture with standardized protocol modules/stacks to interface with industry standards and commonly used software. One major benefit for deploying the virtual sensor test instrumentation is the ability, through a plug-and-play common interface, to convert raw sensor data in either analog or digital form, to an IEEE 1451 standard-based smart sensor, which has instructions to program sensors for a wide variety of

  13. Instrumentation in medical systems

    SciTech Connect

    Chu, W.T.

    1995-05-01

    The demand for clinical use of accelerated heavy charged-particle (proton and light-ion) beams for cancer treatment is now burgeoning worldwide. Clinical trials are underway at more than a dozen accelerators. Several hospital-based accelerator facilities dedicated to radiation treatment of human cancer have been constructed, and their number is growing. Many instruments in medical systems have been developed for modifying extracted particle beams for clinical application, monitoring the delivery of the treatment beams, and controlling the treatment processes to ensure patient safety. These in turn demand new developments of instruments in controlling beam extraction, beam tuning, and beam transportation at the medical systems.

  14. Spectroelectrochemical Instrument Measures TOC

    NASA Technical Reports Server (NTRS)

    Kounaves, Sam

    2011-01-01

    A spectroelectrochemical instrument has been developed for measuring the total organic carbon (TOC) content of an aqueous solution. Measurements of TOC are frequently performed in environmental, clinical, and industrial settings. Until now, techniques for performing such measurements have included, various ly, the use of hazardous reagents, ultraviolet light, or ovens, to promote reactions in which the carbon contents are oxidized. The instrument now being developed is intended to be a safer, more economical means of oxidizing organic carbon and determining the TOC levels of aqueous solutions and for providing a low power/mass unit for use in planetary missions.

  15. Animation of MARDI Instrument

    NASA Technical Reports Server (NTRS)

    2008-01-01

    [figure removed for brevity, see original site] Click on image to view the animation

    This animation shows a zoom into the Mars Descent Imager (MARDI) instrument onboard NASA's Phoenix Mars Lander. The Phoenix team will soon attempt to use a microphone on the MARDI instrument to capture sounds of Mars.

    The Phoenix Mission is led by the University of Arizona, Tucson, on behalf of NASA. Project management of the mission is by NASA's Jet Propulsion Laboratory, Pasadena, Calif. Spacecraft development is by Lockheed Martin Space Systems, Denver.

  16. Advanced sensors and instrumentation

    NASA Technical Reports Server (NTRS)

    Calloway, Raymond S.; Zimmerman, Joe E.; Douglas, Kevin R.; Morrison, Rusty

    1990-01-01

    NASA is currently investigating the readiness of Advanced Sensors and Instrumentation to meet the requirements of new initiatives in space. The following technical objectives and technologies are briefly discussed: smart and nonintrusive sensors; onboard signal and data processing; high capacity and rate adaptive data acquisition systems; onboard computing; high capacity and rate onboard storage; efficient onboard data distribution; high capacity telemetry; ground and flight test support instrumentation; power distribution; and workstations, video/lighting. The requirements for high fidelity data (accuracy, frequency, quantity, spatial resolution) in hostile environments will continue to push the technology developers and users to extend the performance of their products and to develop new generations.

  17. Interfacing to accelerator instrumentation

    SciTech Connect

    Shea, T.J.

    1995-12-31

    As the sensory system for an accelerator, the beam instrumentation provides a tremendous amount of diagnostic information. Access to this information can vary from periodic spot checks by operators to high bandwidth data acquisition during studies. In this paper, example applications will illustrate the requirements on interfaces between the control system and the instrumentation hardware. A survey of the major accelerator facilities will identify the most popular interface standards. The impact of developments such as isochronous protocols and embedded digital signal processing will also be discussed.

  18. Ocean Observation Instrument

    NASA Technical Reports Server (NTRS)

    1993-01-01

    The Airborne Ocean Color Imager (AOCI) was developed by Daedalus Enterprises, Inc. for Ames Research Center under a Small Business Innovation Research (SBIR) contract as a simulator for an advanced oceanographic satellite instrument. The instrument measures water temperature and detects water color in nine wavelengths. Water color indicates chlorophyll content or phytoplankton. After EOCAP assistance and technical improvements, the AOCI was successfully commercialized by Daedalus Enterprises, Inc. One version provides commercial fishing fleets with information about fish locations, and the other is used for oceanographic research.

  19. Microtechnology for instrumentation

    SciTech Connect

    Mariella, R.

    1998-01-01

    For the last two decades, the majority of research and development at LLNL in microtechnology has focused on photonics devices and bulk micromachining, including miccroelectro-mechanical systems and associated areas. For the last ten years, we have used these capabilities to address our analytical instrumentation needs. Just as the miniature photonics have enable the fabrication of analytical instruments that are either higher performance, smaller, more portable, or are combinations of these. Examples of these are our portable thermal cyclers for DNA analysis, our hand-held gas chromatograph, our flow-stream-waveguide-based flow cytometer, and our etched-microchannel electrophoresis systems. This presentation will describe these and related developments.

  20. [Hardening of dental instruments].

    PubMed

    Gerasev, G P

    1981-01-01

    The possibility of prolonging the service life of stomatological instruments by the local hardening of their working parts is discussed. Such hardening should be achieved by using hard and wear-resistant materials. The examples of hardening dental elevators and hard-alloy dental drills are given. New trends in the local hardening of instruments are the treatment of their working parts with laser beams, the application of coating on their surface by the gas-detonation method. The results of research work and trials are presented.

  1. Mutation of sepJ reduces the intercellular signal range of a hetN-dependent paracrine signal, but not of a patS-dependent signal, in the filamentous cyanobacterium Anabaena sp. strain PCC 7120.

    PubMed

    Rivers, Orion S; Videau, Patrick; Callahan, Sean M

    2014-12-01

    Formation and maintenance of a periodic pattern of nitrogen-fixing cells called heterocysts by the filamentous cyanobacterium Anabaena sp. strain PCC 7120 is dependent on regulators encoded by patS and hetN. In this study, genetic mosaic filaments that consisted of cells engineered to produce one of the developmental regulators flanked by target cells capable of reporting the activity of the developmental regulator were used to investigate the intercellular movement of patS- and hetN-dependent activity. We provide evidence that hetN encodes a paracrine signal with a signal range of several cells. The signal that moved between cells did not include the C-terminus of the annotated HetN protein as indicated by similar signal ranges from source cells expressing either hetN-YFP or hetN alone, despite a lack of intercellular exchange of the HetN-YFP fusion protein. Deletion of sepJ, which has been shown to encode a component of intercellular channels, caused a significant decrease in the signal range of hetN expressed from source cells but not of patS. These results are consistent with symplastic transport of a paracrine hetN-dependent signal between vegetative cells of Anabaena.

  2. Heterozygous Mapping Strategy (HetMappS) for High Resolution Genotyping-By-Sequencing Markers: A Case Study in Grapevine

    PubMed Central

    Wang, Minghui; Londo, Jason P.; Acharya, Charlotte B.; Mitchell, Sharon E.; Sun, Qi; Reisch, Bruce; Cadle-Davidson, Lance

    2015-01-01

    Genotyping by sequencing (GBS) provides opportunities to generate high-resolution genetic maps at a low genotyping cost, but for highly heterozygous species, missing data and heterozygote undercalling complicate the creation of GBS genetic maps. To overcome these issues, we developed a publicly available, modular approach called HetMappS, which functions independently of parental genotypes and corrects for genotyping errors associated with heterozygosity. For linkage group formation, HetMappS includes both a reference-guided synteny pipeline and a reference-independent de novo pipeline. The de novo pipeline can be utilized for under-characterized or high diversity families that lack an appropriate reference. We applied both HetMappS pipelines in five half-sib F1 families involving genetically diverse Vitis spp. Starting with at least 116,466 putative SNPs per family, the HetMappS pipelines identified 10,440 to 17,267 phased pseudo-testcross (Pt) markers and generated high-confidence maps. Pt marker density exceeded crossover resolution in all cases; up to 5,560 non-redundant markers were used to generate parental maps ranging from 1,047 cM to 1,696 cM. The number of markers used was strongly correlated with family size in both de novo and synteny maps (r = 0.92 and 0.91, respectively). Comparisons between allele and tag frequencies suggested that many markers were in tandem repeats and mapped as single loci, while markers in regions of more than two repeats were removed during map curation. Both pipelines generated similar genetic maps, and genetic order was strongly correlated with the reference genome physical order in all cases. Independently created genetic maps from shared parents exhibited nearly identical results. Flower sex was mapped in three families and correctly localized to the known sex locus in all cases. The HetMappS pipeline could have wide application for genetic mapping in highly heterozygous species, and its modularity provides opportunities to

  3. Music: Instrumental Techniques, Woodwinds.

    ERIC Educational Resources Information Center

    Baker, Melvin

    A course in introduction to music emphasizing modes and forms is presented. The approach used is a laboratory approach in which pupils will develop skill in playing wood-wind instruments, sing, listen to, read and compose music with emphasis on identification of elementary concepts of mode and form. Course objectives include: (1) pupil will select…

  4. Experimenting with Woodwind Instruments

    ERIC Educational Resources Information Center

    LoPresto, Michael C.

    2007-01-01

    Simple experiments involving musical instruments of the woodwind family can be used to demonstrate the basic physics of vibrating air columns in resonance tubes using nothing more than straightforward measurements and data collection hardware and software. More involved experimentation with the same equipment can provide insight into the effects…

  5. Neutron instrumentation for biology

    SciTech Connect

    Mason, S.A.

    1994-12-31

    In the October 1994 round of proposals at the ILL, the external biology review sub- committee was asked to allocate neutron beam time to a wide range of experiments, on almost half the total number of scheduled neutron instruments: on 3 diffractometers, on 3 small angle scattering instruments, and on some 6 inelastic scattering spectrometers. In the 3.5 years since the temporary reactor shutdown, the ILL`s management structure has been optimized, budgets and staff have been trimmed, the ILL reactor has been re-built, and many of the instruments up-graded, many powerful (mainly Unix) workstations have been introduced, and the neighboring European Synchrotron Radiation Facility has established itself as the leading synchrotron radiation source and has started its official user program. The ILL reactor remains the world`s most intense dedicated neutron source. In this challenging context, it is of interest to review briefly the park of ILL instruments used to study the structure and energetics of small and large biological systems. A brief summary will be made of each class of experiments actually proposed in the latest ILL proposal round.

  6. AC resistance measuring instrument

    DOEpatents

    Hof, P.J.

    1983-10-04

    An auto-ranging AC resistance measuring instrument for remote measurement of the resistance of an electrical device or circuit connected to the instrument includes a signal generator which generates an AC excitation signal for application to a load, including the device and the transmission line, a monitoring circuit which provides a digitally encoded signal representing the voltage across the load, and a microprocessor which operates under program control to provide an auto-ranging function by which range resistance is connected in circuit with the load to limit the load voltage to an acceptable range for the instrument, and an auto-compensating function by which compensating capacitance is connected in shunt with the range resistance to compensate for the effects of line capacitance. After the auto-ranging and auto-compensation functions are complete, the microprocessor calculates the resistance of the load from the selected range resistance, the excitation signal, and the load voltage signal, and displays of the measured resistance on a digital display of the instrument. 8 figs.

  7. AC Resistance measuring instrument

    DOEpatents

    Hof, Peter J.

    1983-01-01

    An auto-ranging AC resistance measuring instrument for remote measurement of the resistance of an electrical device or circuit connected to the instrument includes a signal generator which generates an AC excitation signal for application to a load, including the device and the transmission line, a monitoring circuit which provides a digitally encoded signal representing the voltage across the load, and a microprocessor which operates under program control to provide an auto-ranging function by which range resistance is connected in circuit with the load to limit the load voltage to an acceptable range for the instrument, and an auto-compensating function by which compensating capacitance is connected in shunt with the range resistance to compensate for the effects of line capacitance. After the auto-ranging and auto-compensation functions are complete, the microprocessor calculates the resistance of the load from the selected range resistance, the excitation signal, and the load voltage signal, and displays of the measured resistance on a digital display of the instrument.

  8. Process Instrumentation. Teacher Edition.

    ERIC Educational Resources Information Center

    Brown, A. O., III; Fowler, Malcolm

    This module provides instructional materials that are designed to help teachers train students in job skills for entry-level jobs as instrumentation technicians. This text addresses the basics of troubleshooting control loops, and the transducers, transmitters, signal conditioners, control valves, and controllers that enable process systems to…

  9. Instrument for assaying radiation

    DOEpatents

    Coleman, Jody Rustyn; Farfan, Eduardo B.

    2016-03-22

    An instrument for assaying radiation includes a flat panel detector having a first side opposed to a second side. A collimated aperture covers at least a portion of the first side of the flat panel detector. At least one of a display screen or a radiation shield may cover at least a portion of the second side of the flat panel detector.

  10. Instrumentation Control Technician.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Center on Education and Training for Employment.

    This document contains 22 units to consider for use in a tech prep competency profile for the occupation of instrumentation control technician. All the units listed will not necessarily apply to every situation or tech prep consortium, nor will all the competencies within each unit be appropriate. Several units appear within each specific…

  11. University Reactor Instrumentation Program

    SciTech Connect

    Vernetson, W.G.

    1992-11-01

    Recognizing that the University Reactor Instrumentation Program was developed in response to widespread needs in the academic community for modernization and improvement of research and training reactors at institutions such as the University of Florida, the items proposed to be supported by this grant over its two year period have been selected as those most likely to reduce foreed outages, to meet regulatory concerns that had been expressed in recent years by Nuclear Regulatory Commission inspectors or to correct other facility problems and limitations. Department of Energy Grant Number DE-FG07-90ER129969 was provided to the University of Florida Training Reactor(UFTR) facility through the US Department of Energy's University Reactor Instrumentation Program. The original proposal submitted in February, 1990 requested support for UFTR facility instrumentation and equipment upgrades for seven items in the amount of $107,530 with $13,800 of this amount to be the subject of cost sharing by the University of Florida and $93,730 requested as support from the Department of Energy. A breakdown of the items requested and total cost for the proposed UFTR facility instrumentation and equipment improvements is presented.

  12. HARMONI instrument control electronics

    NASA Astrophysics Data System (ADS)

    Gigante, José V.; Rodríguez Ramos, Luis F.; Zins, Gerard; Schnetler, Hermine; Pecontal, Arlette; Herreros, José Miguel; Clarke, Fraser; Bryson, Ian; Thatte, Niranjan

    2014-07-01

    HARMONI is an integral field spectrograph working at visible and near-infrared wavelengths over a range of spatial scales from ground layer corrected to fully diffraction-limited. The instrument has been chosen to be part of the first-light complement at the European Extremely Large Telescope (E-ELT). This paper describes the instrument control electronics to be developed at IAC. The large size of the HARMONI instrument, its cryogenic operation, and the fact that it must operate with enhanced reliability is a challenge from the point of view of the control electronics design. The present paper describes a design proposal based on the current instrument requirements and intended to be fully compliant with the ESO E-ELT standards, as well as with the European EMC and safety standards. The modularity of the design and the use of COTS standard hardware will benefit the project in several aspects, as reduced costs, shorter schedule by the use of commercially available components, and improved quality by the use of well proven solutions.

  13. Rain radar instrument definition

    NASA Astrophysics Data System (ADS)

    Vincent, Nicolas; Chenebault, J.; Suinot, Noel; Mancini, Paolo L.

    1996-12-01

    As a result of a pre-phase a study, founded by ESA, this paper presents the definition of a spaceborne Rain Radar, candidate instrument for earth explorer precipitation mission. Based upon the description of user requirements for such a dedicated mission, a mission analysis defines the most suitable space segment. At system level, a parametric analysis compares pros and cons of instrument concepts associated with rain rate retrieval algorithms in order to select the most performing one. Several trade-off analysis at subsystem level leads then to the definition of the proposed design. In particular, as pulse compression is implemented in order to increase the radar sensitivity, the selected method to achieve a pulse response with a side-lobe level below--60 dB is presented. Antenna is another critical rain radar subsystem and several designs are com pared: direct radiating array, single or dual reflector illuminated by single or dual feed arrays. At least, feasibility of centralized amplification using TWTA is compared with criticality of Tx/Rx modules for distributed amplification. Mass and power budgets of the designed instrument are summarized as well as standard deviations and bias of simulated rain rate retrieval profiles. The feasibility of a compliant rain radar instrument is therefore demonstrated.

  14. Portable dynamic fundus instrument

    NASA Technical Reports Server (NTRS)

    Taylor, Gerald R. (Inventor); Meehan, Richard T. (Inventor); Hunter, Norwood R. (Inventor); Caputo, Michael P. (Inventor); Gibson, C. Robert (Inventor)

    1992-01-01

    A portable diagnostic image analysis instrument is disclosed for retinal funduscopy in which an eye fundus image is optically processed by a lens system to a charge coupled device (CCD) which produces recordable and viewable output data and is simultaneously viewable on an electronic view finder. The fundus image is processed to develop a representation of the vessel or vessels from the output data.

  15. Instrument for Textbook Assessment.

    ERIC Educational Resources Information Center

    Huetteman, Julie Doidge

    An instrument to assist in assessing textbooks was created to provide a concise format for comparison and evaluation. Textbook characteristics were selected to illustrate content and proportion of characteristics of textbooks. Nine textbook characteristics were selected for quantifying the content areas of textbooks: (1) number of pages in the…

  16. Music: Instrumental Techniques, Percussion.

    ERIC Educational Resources Information Center

    Pearl, Jesse

    A course in introduction to music emphasizing harmony is presented. The approach used is a laboratory approach in which pupils will develop skill in playing percussion instruments, sing, listen to, read and compose music with emphasis on elementary concepts of harmony. Course objectives include: (1) The student will recognize duple, triple,…

  17. The G protein-coupled receptor heterodimer network (GPCR-HetNet) and its hub components.

    PubMed

    Borroto-Escuela, Dasiel O; Brito, Ismel; Romero-Fernandez, Wilber; Di Palma, Michael; Oflijan, Julia; Skieterska, Kamila; Duchou, Jolien; Van Craenenbroeck, Kathleen; Suárez-Boomgaard, Diana; Rivera, Alicia; Guidolin, Diego; Agnati, Luigi F; Fuxe, Kjell

    2014-05-14

    G protein-coupled receptors (GPCRs) oligomerization has emerged as a vital characteristic of receptor structure. Substantial experimental evidence supports the existence of GPCR-GPCR interactions in a coordinated and cooperative manner. However, despite the current development of experimental techniques for large-scale detection of GPCR heteromers, in order to understand their connectivity it is necessary to develop novel tools to study the global heteroreceptor networks. To provide insight into the overall topology of the GPCR heteromers and identify key players, a collective interaction network was constructed. Experimental interaction data for each of the individual human GPCR protomers was obtained manually from the STRING and SCOPUS databases. The interaction data were used to build and analyze the network using Cytoscape software. The network was treated as undirected throughout the study. It is comprised of 156 nodes, 260 edges and has a scale-free topology. Connectivity analysis reveals a significant dominance of intrafamily versus interfamily connections. Most of the receptors within the network are linked to each other by a small number of edges. DRD2, OPRM, ADRB2, AA2AR, AA1R, OPRK, OPRD and GHSR are identified as hubs. In a network representation 10 modules/clusters also appear as a highly interconnected group of nodes. Information on this GPCR network can improve our understanding of molecular integration. GPCR-HetNet has been implemented in Java and is freely available at http://www.iiia.csic.es/~ismel/GPCR-Nets/index.html.

  18. The G protein-coupled receptor heterodimer network (GPCR-HetNet) and its hub components.

    PubMed

    Borroto-Escuela, Dasiel O; Brito, Ismel; Romero-Fernandez, Wilber; Di Palma, Michael; Oflijan, Julia; Skieterska, Kamila; Duchou, Jolien; Van Craenenbroeck, Kathleen; Suárez-Boomgaard, Diana; Rivera, Alicia; Guidolin, Diego; Agnati, Luigi F; Fuxe, Kjell

    2014-01-01

    G protein-coupled receptors (GPCRs) oligomerization has emerged as a vital characteristic of receptor structure. Substantial experimental evidence supports the existence of GPCR-GPCR interactions in a coordinated and cooperative manner. However, despite the current development of experimental techniques for large-scale detection of GPCR heteromers, in order to understand their connectivity it is necessary to develop novel tools to study the global heteroreceptor networks. To provide insight into the overall topology of the GPCR heteromers and identify key players, a collective interaction network was constructed. Experimental interaction data for each of the individual human GPCR protomers was obtained manually from the STRING and SCOPUS databases. The interaction data were used to build and analyze the network using Cytoscape software. The network was treated as undirected throughout the study. It is comprised of 156 nodes, 260 edges and has a scale-free topology. Connectivity analysis reveals a significant dominance of intrafamily versus interfamily connections. Most of the receptors within the network are linked to each other by a small number of edges. DRD2, OPRM, ADRB2, AA2AR, AA1R, OPRK, OPRD and GHSR are identified as hubs. In a network representation 10 modules/clusters also appear as a highly interconnected group of nodes. Information on this GPCR network can improve our understanding of molecular integration. GPCR-HetNet has been implemented in Java and is freely available at http://www.iiia.csic.es/~ismel/GPCR-Nets/index.html. PMID:24830558

  19. Instrumentation problems for physicians.

    PubMed

    Turner, G O

    1980-01-01

    The physician has, for whatever reasons, diminished his or her level of involvement on the team dedicated to developing, refining, and evaluating medical technology. As a result, the challenge confronting the physician and the technology development team today is to orchestrate a team structure that will ensure the greatest input and commitment from physicians and other professionals during current and future technology development. The charges of cost escalation and dehumanization in our system of health care delivery will also be discussed, as will the lack of, or confusion about, access to data concerning cost of a given instrument, and fuzzy semantics and perspectives on technology and instrumentation. The author suggests answers to, or means to ameliorate, the problems.

  20. A GC Instrument Simulator

    NASA Astrophysics Data System (ADS)

    Armitage, D. Bruce

    1999-02-01

    This simulator was developed to help students beginning the study of gas chromatographic instruments to understand their operation. It is not meant to teach chromatographic theory. The instrument simulator is divided into 5 sections. One is for sample preparation. Another is used to manage carrier gases and choose a detector and column. The third sets the conditions for either isothermal or programmed temperature operation. A fourth section models manual injections, and the fifth is the autosampler. The operator has a choice among 6 columns of differing diameters and packing polarities and a choice of either isothermal or simple one-stage temperature programming. The simulator can be operated in either single-sample mode or as a 10-sample autosampler. The integrator has two modes of operation, a "dumb" mode in which only the retention time, area of the peak, and percentage area are listed and a "smart" mode that also lists the components' identities. The identities are obtained from a list of names and retention times created by the operator. Without this list only the percentages and areas are listed. The percentages are based on the areas obtained from the chromatogram and not on the actual percentages assigned during sample preparation. The data files for the compounds used in the simulator are ASCII files and can be edited easily to add more compounds than the 11 included with the simulator. A maximum of 10 components can be used in any one sample. Sample mixtures can be made on a percent-by-volume basis, but not by mass of sample per volume of solvent. A maximum of 30 compounds can be present in any one file, but the number of files is limited only by the operating system. (I suggest that not more than 20 compounds be used in any one file, as scrolling through large numbers of compounds is annoying to say the least.) File construction and layout are discussed in detail in the User's Manual. Chromatograms are generated by calculating a retention time based on

  1. KEKB beam instrumentation systems

    NASA Astrophysics Data System (ADS)

    Arinaga, M.; Flanagan, J.; Hiramatsu, S.; Ieiri, T.; Ikeda, H.; Ishii, H.; Kikutani, E.; Mimashi, T.; Mitsuhashi, T.; Mizuno, H.; Mori, K.; Tejima, M.; Tobiyama, M.

    2003-02-01

    For the stable high-luminosity operation and luminosity increase, the electron and positron storage rings of the KEK B-Factory (KEKB) is equipped with various beam instrumentations, which have been working well since the start of the commissioning in December, 1998. Details and performance of the beam-position monitor system based on the spectrum analysis using DSPs, the turn-by-turn BPM with four-dimensional function available for measurements of the individual bunch position, phase and intensity, the parametric beam-DCCTs designed so as to avoid the magnetic-core-selection problems for the parametric flux modulation, the bunch-by-bunch feedback system indispensable to suppress the strong multibunch instabilities in KEKB, the various optical beam diagnostic systems, such as synchrotron radiation interferometers for precise beam-size measurement, the tune meters, the bunch length monitors and the beam-loss monitors are described. Delicate machine tuning of KEKB is strongly supported by these instrumentations.

  2. Solar radioastronomical instruments

    NASA Astrophysics Data System (ADS)

    Gonze, R.

    Instruments for detecting and recording the radio emissions of the sun are required to cover the entire electromagnetic spectrum, measure intensity and polarization, as well as the region of the emissions, and display high resolution in both space and time. Radioheliographic images of the sun are made from wavelengths outside of the visible, and yield images based on a grid of relative intensities of varying fineness of resolution. Radioelectric isophote contours can be generated using radiotelescopes at specific receptive frequencies, and interferometric techniques permit the employment of multiple paraboloidal receivers to construct a synthetic image of greater resolution than possible with a single antenna. Dynamic radiospectrography is used to examine transitory solar radio emissions where fine structures are produced in frequency bands covering at least an octave. Multichannel radiospectrographic equipment with many receptors tuned to discrete frequencies and regularly adjusted permits coverage of broad frequency bands, with digital control to augment the dynamics of the instruments.

  3. THE ARCADE 2 INSTRUMENT

    SciTech Connect

    Singal, J.; Fixsen, D. J.; Kogut, A.; Mirel, P.; Wollack, E.; Levin, S.; Seiffert, M.; Limon, M.; Lubin, P.; Villela, T.; Wuensche, C. A.

    2011-04-01

    The second generation Absolute Radiometer for Cosmology, Astrophysics, and Diffuse Emission (ARCADE 2) instrument is a balloon-borne experiment to measure the radiometric temperature of the cosmic microwave background and Galactic and extragalactic emission at six frequencies from 3 to 90 GHz. ARCADE 2 utilizes a double-nulled design where emission from the sky is compared to that from an external cryogenic full-aperture blackbody calibrator by cryogenic switching radiometers containing internal blackbody reference loads. In order to further minimize sources of systematic error, ARCADE 2 features a cold fully open aperture with all radiometrically active components maintained at near 2.7 K without windows or other warm objects, achieved through a novel thermal design. We discuss the design and performance of the ARCADE 2 instrument in its 2005 and 2006 flights.

  4. Patient specific instrumentation.

    PubMed

    Lionberger, David R; Crocker, Catherine L; Chen, Vincent

    2014-09-01

    Patient specific instrumentation (PSI) has recently been developed as a replacement for traditional instrumentation in total knee arthroplasty (TKA). The study aim was to assess efficiency via the mean total OR time using the PSI versus computer-assisted (CAS) TKAs with accuracy as a secondary endpoint. Sixty patients were randomized to CAS or PSI. A formula was developed to derive a profit ratio (PR) that incorporated costs, revenue, and total OR time. The PSI cases were 1.45 times more profitable than CAS allowing for approximately 3 PSI cases versus 2 CAS cases in one 8 hour OR day. Results from this series show that PSI improves OR efficiency, but does not improve accuracy.

  5. Data acquisition instruments: Psychopharmacology

    SciTech Connect

    Hartley, D.S. III

    1998-01-01

    This report contains the results of a Direct Assistance Project performed by Lockheed Martin Energy Systems, Inc., for Dr. K. O. Jobson. The purpose of the project was to perform preliminary analysis of the data acquisition instruments used in the field of psychiatry, with the goal of identifying commonalities of data and strategies for handling and using the data in the most advantageous fashion. Data acquisition instruments from 12 sources were provided by Dr. Jobson. Several commonalities were identified and a potentially useful data strategy is reported here. Analysis of the information collected for utility in performing diagnoses is recommended. In addition, further work is recommended to refine the commonalities into a directly useful computer systems structure.

  6. Radar measurement instruments

    NASA Astrophysics Data System (ADS)

    Hartl, P.

    1983-02-01

    The radar techniques used for Earth observation are reviewed. Range, direction and speed measuring techniques, and the principles of scatterometers, side-looking radar, altimeters and SAR are discussed. The ERS-1 radar package including the active microwave instrumentation and the radar altimeter are described. The analysis of the calibration problems leads to the conclusion that only the test of the system loop as a whole, besides the individual part tests, can provide a calibration in the absolute sense.

  7. Instrumentation and diagnostics

    SciTech Connect

    Nakaishi, C.V.; Bedick, R.C.

    1990-12-01

    This Technology Status Report describes research and accomplishments for the Instrumentation and Diagnostics (I D) Projects within the Advanced Research and Technology Development (AR TD) Program of the United States Department of Energy (DOE) Office of Fossil Energy (FE). Process understanding and control can be improved through the development of advanced instrumentation and diagnostics. The thrust of the I D Projects is to further develop existing measurement and control techniques for application to advanced coal-based technologies. Project highlights are: an inductively coupled plasma (ICP) instrument has been developed to analyze trace elements in gasification and combustion process streams. An in situ two-color Mie scattering technique with LSS can simultaneously measure the size, velocity, and elemental composition of coal particles during combustion. A high-temperature, fluorescence thermometry technique has accurately measured gas temperatures during field testing in combustion and gasification environments. Expert systems have been developed to improve the control of advanced coal-based processes. Capacitance flowmeters were developed to determine the mass flowrate, solid volume fraction, and particle velocities of coal slurries. 32 refs., 9 figs.

  8. Mandolin Family Instruments

    NASA Astrophysics Data System (ADS)

    Cohen, David J.; Rossing, Thomas D.

    The mandolin family of instruments consists of plucked chordophones, each having eight strings in four double courses. With the exception of the mandobass, the courses are tuned in intervals of fifths, as are the strings in violin family instruments. The soprano member of the family is the mandolin, tuned G3-D4-A4-E5. The alto member of the family is the mandola, tuned C3-G3-D4-A4. The mandola is usually referred to simply as the mandola in the USA, but is called the tenor mandola in Europe. The tenor member of the family is the octave mandolin, tuned G2-D3-A3-E4. It is referred to as the octave mandolin in the USA, and as the octave mandola in Europe. The baritone member of the family is the mandocello, or mandoloncello, tuned C2-G2-D3-A3. A variant of the mandocello not common in the USA is the five-course liuto moderno, or simply liuto, designed for solo repertoire. Its courses are tuned C2-G2-D3-A3-E4. A mandobass was also made by more than one manufacturer during the early twentieth century, though none are manufactured today. They were fretted instruments with single string courses tuned E1-A1-D2-G2. There are currently a few luthiers making piccolo mandolins, tuned C4-G4-D5-A5.

  9. Impact dynamics instrumentation

    NASA Technical Reports Server (NTRS)

    Mccormck, R. F.

    1986-01-01

    One of the tasks specified in the NASA Langley controlled impact demonstration (CID) work package was to furnish dynamic instrumentation sensors. The types of instrumentation sensors required were accelerometers for aircraft structural loads measurements, seat belt load cells to measure anthropomorphic dummy responses to the aircraft impact, and strain gage bending bridges to measure the aircraft fuselage and wing bending during impact. The objective in the selection of dynamic instrumentation for the CID was to provide 352 of the highest quality transducers and remain within budget allocation. The transducers that were selected for the CID evaluation process were each subjected to rigorous laboratory acceptance tests and to aircraft fuselage section drop tests at the LaRC Impact Dynamics Research Facility. Data compiled from this series of tests showed the selected transducers to be best suited for the CID mission requirement. The transducers installation technique on the airframe proved successful. The transducer quality assurance was guaranteed through rigorous acceptance testing. Data acquired was 97.0%.

  10. An ice lithography instrument

    NASA Astrophysics Data System (ADS)

    Han, Anpan; Chervinsky, John; Branton, Daniel; Golovchenko, J. A.

    2011-06-01

    We describe the design of an instrument that can fully implement a new nanopatterning method called ice lithography, where ice is used as the resist. Water vapor is introduced into a scanning electron microscope (SEM) vacuum chamber above a sample cooled down to 110 K. The vapor condenses, covering the sample with an amorphous layer of ice. To form a lift-off mask, ice is removed by the SEM electron beam (e-beam) guided by an e-beam lithography system. Without breaking vacuum, the sample with the ice mask is then transferred into a metal deposition chamber where metals are deposited by sputtering. The cold sample is then unloaded from the vacuum system and immersed in isopropanol at room temperature. As the ice melts, metal deposited on the ice disperses while the metals deposited on the sample where the ice had been removed by the e-beam remains. The instrument combines a high beam-current thermal field emission SEM fitted with an e-beam lithography system, cryogenic systems, and a high vacuum metal deposition system in a design that optimizes ice lithography for high throughput nanodevice fabrication. The nanoscale capability of the instrument is demonstrated with the fabrication of nanoscale metal lines.

  11. Simulation visualization through dynamic instrumentation

    SciTech Connect

    Bisset, K.R.

    1998-09-01

    The goal of the instrument composition system is to allow a simulation user to dynamically create instruments as a simulation executes. Instruments can include graphical displays, data collectors, and debugging aides. Instruments are made up of small building blocks which can be easily combined into larger, more complex instruments. Through the sue of an Attribute Server (a distributed publication/subscription mechanism), the actors and instruments in a simulation can interact without direct knowledge of each other. Instead, each actor publishes the attributes which it has available. An instrument subscribes to the attributes in which it is interested, and is notified whenever the value of one of these attribute changes. An instrument can also publish attributes for use by other instruments. Since the Attribute Server is distributed, the publisher of an attribute need not execute on the same machine as the subscriber. This allows CPU intensive data visualization to execute on separate machines from the simulation, minimizing the impact on the simulation.

  12. FHR Process Instruments

    SciTech Connect

    Holcomb, David Eugene

    2015-01-01

    Fluoride salt-cooled High temperature Reactors (FHRs) are entering into early phase engineering development. Initial candidate technologies have been identified to measure all of the required process variables. The purpose of this paper is to describe the proposed measurement techniques in sufficient detail to enable assessment of the proposed instrumentation suite and to support development of the component technologies. This paper builds upon the instrumentation chapter of the recently published FHR technology development roadmap. Locating instruments outside of the intense core radiation and high-temperature fluoride salt environment significantly decreases their environmental tolerance requirements. Under operating conditions, FHR primary coolant salt is a transparent, low-vapor-pressure liquid. Consequently, FHRs can employ standoff optical measurements from above the salt pool to assess in-vessel conditions. For example, the core outlet temperature can be measured by observing the fuel s blackbody emission. Similarly, the intensity of the core s Cerenkov glow indicates the fission power level. Short-lived activation of the primary coolant provides another means for standoff measurements of process variables. The primary coolant flow and neutron flux can be measured using gamma spectroscopy along the primary coolant piping. FHR operation entails a number of process measurements. Reactor thermal power and core reactivity are the most significant variables for process control. Thermal power can be determined by measuring the primary coolant mass flow rate and temperature rise across the core. The leading candidate technologies for primary coolant temperature measurement are Au-Pt thermocouples and Johnson noise thermometry. Clamp-on ultrasonic flow measurement, that includes high-temperature tolerant standoffs, is a potential coolant flow measurement technique. Also, the salt redox condition will be monitored as an indicator of its corrosiveness. Both

  13. Topics in Chemical Instrumentation, Cl. Thermoluminescence: Part II. Instrumentation.

    ERIC Educational Resources Information Center

    Manche, Emanuel P.

    1979-01-01

    Presents part two on the use of the detection of thermoluminescence as an analytical tool for the chemistry laboratory and allied science. This part discusses instrumentation used and investigates recent developments in instrumentation for thermoluminescence. (HM)

  14. Volume phase holographic grating performance on the VIRUS-P instrument

    NASA Astrophysics Data System (ADS)

    Adams, Joshua J.; Hill, Gary J.; MacQueen, Phillip J.

    2008-07-01

    The Visible Integral-field Replicable Unit Spectrograph Prototype (VIRUS-P) has been in operation on the Harlan J Smith 2.7m Telescope at McDonald Observatory since October of 2006. The prototype was created to test the design and science capabilities of the full VIRUS instrument, wherein 150 copies of the spectrograph will be installed on the Hobby Eberly Telescope (HET). We here discuss the specialized test bench built to assess the blue optimized Volume Phase Holographic (VPH) grating performance. We also give lab and on-telescope efficiency measurements for three such gratings in the wavelength range 3400-6800Å. Two sources of stray light relevant to most spectrograph designs are also discussed.

  15. Instrumentation: Software-Driven Instrumentation: The New Wave.

    ERIC Educational Resources Information Center

    Salit, M. L.; Parsons, M. L.

    1985-01-01

    Software-driven instrumentation makes measurements that demand a computer as an integral part of either control, data acquisition, or data reduction. The structure of such instrumentation, hardware requirements, and software requirements are discussed. Examples of software-driven instrumentation (such as wavelength-modulated continuum source…

  16. LBL's Pollution Instrumentation Comparability Program.

    ERIC Educational Resources Information Center

    McLaughlin, R. D.; And Others

    1979-01-01

    Contained are condensed excerpts from the Lawrence Berkeley Laboratory Survey of Instrumentation for Environmental Monitoring. The survey describes instrumentation used to analyze air and water quality, radiation emissions, and biomedical impacts. (BB)

  17. Precision Instrument and Equipment Repairers.

    ERIC Educational Resources Information Center

    Wyatt, Ian

    2001-01-01

    Explains the job of precision instrument and equipment repairers, who work on cameras, medical equipment, musical instruments, watches and clocks, and industrial measuring devices. Discusses duties, working conditions, employment and earnings, job outlook, and skills and training. (JOW)

  18. ZBLAN Viscosity Instrumentation

    NASA Technical Reports Server (NTRS)

    Kaukler, William

    2001-01-01

    The past year's contribution from Dr. Kaukler's experimental effort consists of these 5 parts: a) Construction and proof-of-concept testing of a novel shearing plate viscometer designed to produce small shear rates and operate at elevated temperatures; b) Preparing nonlinear polymeric materials to serve as standards of nonlinear Theological behavior; c) Measurements and evaluation of above materials for nonlinear rheometric behavior at room temperature using commercial spinning cone and plate viscometers available in the lab; d) Preparing specimens from various forms of pitch for quantitative comparative testing in a Dynamic Mechanical Analyzer, Thermal Mechanical Analyzer; and Archeological Analyzer; e) Arranging to have sets of pitch specimens tested using the various instruments listed above, from different manufacturers, to form a baseline of the viscosity variation with temperature using the different test modes offered by these instruments by compiling the data collected from the various test results. Our focus in this project is the shear thinning behavior of ZBLAN glass over a wide range of temperature. Experimentally, there are no standard techniques to perform such measurements on glasses, particularly at elevated temperatures. Literature reviews to date have shown that shear thinning in certain glasses appears to occur, but no data is available for ZBLAN glass. The best techniques to find shear thinning behavior require the application of very low rates of shear. In addition, because the onset of the thinning behavior occurs at an unknown elevated temperature, the instruments used in this study must provide controlled low rates of shear and do so for temperatures approaching 600 C. In this regard, a novel shearing parallel plate viscometer was designed and a prototype built and tested.

  19. Biomagnetic instrumentation and measurement

    NASA Technical Reports Server (NTRS)

    Iufer, E. J.

    1978-01-01

    The instruments and techniques of biomagnetic measurement have progressed greatly in the past 15 years and are now of a quality appropriate to clinical applications. The paper reports on recent developments in the design and application of SQUID (Superconducting Quantum Interference Device) magnetometers to biomagnetic measurement. The discussion covers biomagnetic field levels, magnetocardiography, magnetic susceptibility plethysmography, ambient noise and sensor types, principles of operation of a SQUID magnetometer, and laboratory techniques. Of the many promising applications of noninvasive biomagnetic measurement, magnetocardiography is the most advanced and the most likely to find clinical application in the near future.

  20. Aerodynamically stabilized instrument platform

    NASA Technical Reports Server (NTRS)

    Bland, Geoffrey L. (Inventor); Miles, Ted K. (Inventor)

    2012-01-01

    A suspension apparatus for suspending instrumentation from an airborne platform may include a generally longitudinal boom having a payload end and a tail end. Yaw and pitch stabilizers may be disposed at the tail end of the boom. A mast that may be selectively translatable on the boom may connect the boom to a tether line of the airborne platform. The payload may be attached to the payload end of the boom. The mast may be positioned axially along the boom at the center of gravity of the combination of the payload, boom, pitch stabilizer, and yaw stabilizer.

  1. Diamonds for beam instrumentation

    SciTech Connect

    Griesmayer, Erich

    2013-04-19

    Diamond is perhaps the most versatile, efficient and radiation tolerant material available for use in beam detectors with a correspondingly wide range of applications in beam instrumentation. Numerous practical applications have demonstrated and exploited the sensitivity of diamond to charged particles, photons and neutrons. In this paper, a brief description of a generic diamond detector is given and the interaction of the CVD diamond detector material with protons, electrons, photons and neutrons is presented. Latest results of the interaction of sCVD diamond with 14 MeV mono-energetic neutrons are shown.

  2. Diaphragms for Aeronautic Instruments

    NASA Technical Reports Server (NTRS)

    Hersey, M D

    1924-01-01

    This investigation was carried out at the request of the National Advisory Committee for Aeronautics and comprises an outline of historical developments and theoretical principles, together with a discussion of expedients for making the most effective use of existing diaphragms actuated by the hydrostatic pressure form an essential element of a great variety instruments for aeronautic and other technical purposes. The various physical data needed as a foundation for rational methods of diaphragm design have not, however, been available hitherto except in the most fragmentary form.

  3. A new innovative instrument for space plasma instrumentation

    NASA Technical Reports Server (NTRS)

    Torbert, Roy B.

    1993-01-01

    The Faraday Ring Ammeter was the subject of this grant for a new innovative instrument for space plasma instrumentation. This report summarizes our progress in this work. Briefly, we have conducted an intensive series of experiments and trials over three years, testing some five configurations of the instrument to measure currents, resulting in two Ph.D. theses, supported by this grant, and two flight configurations of the instrument. The first flight would have been on a NASA-Air Force collaborative sounding rocket, but was not flown because of instrumental difficulties. The second has been successfully integrated on the NASA Auroral Turbulence payload which is to be launched in February, 1994.

  4. Mallet Instruments Challenge Beginning Percussionists.

    ERIC Educational Resources Information Center

    Grumley, Fred

    1983-01-01

    Orff mallet instruments should be used in beginning band classes. Adding mallet instruments would expand a beginner's concept of percussion instruments. Just as important, the percussion section would provide a solid melodic and harmonic foundation to assist beginning wind instrumentalists with their insecurities about pitch. (RM)

  5. Spacecraft instrument calibration and stability

    NASA Technical Reports Server (NTRS)

    Gille, J. C.; Feldman, P.; Hudson, R.; Lean, J.; Madden, R.; Mcmaster, L.; Mount, G.; Rottman, G.; Simon, P. C.

    1989-01-01

    The following topics are covered: instrument degradation; the Solar Backscatter Ultraviolet (SBUV) Experiment; the Total Ozone Mapping Spectrometer (TOMS); the Stratospheric Aerosol and Gas Experiment 1 (SAGE-1) and SAGE-2 instruments; the Solar Mesosphere Explorer (SME) UV ozone and near infrared airglow instruments; and the Limb Infrared Monitor of the Stratosphere (LIMS).

  6. Instrument Remote Control via the Astronomical Instrument Markup Language

    NASA Technical Reports Server (NTRS)

    Sall, Ken; Ames, Troy; Warsaw, Craig; Koons, Lisa; Shafer, Richard

    1998-01-01

    The Instrument Remote Control (IRC) project ongoing at NASA's Goddard Space Flight Center's (GSFC) Information Systems Center (ISC) supports NASA's mission by defining an adaptive intranet-based framework that provides robust interactive and distributed control and monitoring of remote instruments. An astronomical IRC architecture that combines the platform-independent processing capabilities of Java with the power of Extensible Markup Language (XML) to express hierarchical data in an equally platform-independent, as well as human readable manner, has been developed. This architecture is implemented using a variety of XML support tools and Application Programming Interfaces (API) written in Java. IRC will enable trusted astronomers from around the world to easily access infrared instruments (e.g., telescopes, cameras, and spectrometers) located in remote, inhospitable environments, such as the South Pole, a high Chilean mountaintop, or an airborne observatory aboard a Boeing 747. Using IRC's frameworks, an astronomer or other scientist can easily define the type of onboard instrument, control the instrument remotely, and return monitoring data all through the intranet. The Astronomical Instrument Markup Language (AIML) is the first implementation of the more general Instrument Markup Language (IML). The key aspects of our approach to instrument description and control applies to many domains, from medical instruments to machine assembly lines. The concepts behind AIML apply equally well to the description and control of instruments in general. IRC enables us to apply our techniques to several instruments, preferably from different observatories.

  7. The QUIET Instrument

    SciTech Connect

    Bischoff, C.; et al.

    2012-07-01

    The Q/U Imaging ExperimenT (QUIET) is designed to measure polarization in the Cosmic Microwave Background, targeting the imprint of inflationary gravitational waves at large angular scales ({approx}1{sup o}). Between 2008 October and 2010 December, two independent receiver arrays were deployed sequentially on a 1.4m side-fed Dragonian telescope. The polarimeters which form the focal planes use a highly compact design based on High Electron Mobility Transistors (HEMTs) that provides simultaneous measurements of the Stokes parameters Q, U, and I in a single module. The 17-element Q-band polarimeter array, with a central frequency of 43.1 GHz, has the best sensitivity (69 {mu}Ks{sup 1/2}) and the lowest instrumental systematic errors ever achieved in this band, contributing to the tensor-to-scalar ratio at r < 0:1. The 84-element W-band polarimeter array has a sensitivity of 87 {mu}Ks{sup 1/2} at a central frequency of 94.5 GHz. It has the lowest systematic errors to date, contributing at r < 0:01. The two arrays together cover multipoles in the range {ell} {approx} 25 -- 975. These are the largest HEMT-based arrays deployed to date. This article describes the design, calibration, performance of, and sources of systematic error for the instrument.

  8. An Instrumental Innovation

    NASA Technical Reports Server (NTRS)

    1978-01-01

    Think of guitars and you think of rock and country music, or the vigorous rhythms of the gypsy flamenco, or perhaps the classical strumming of a Segovia. About the last thing you would associate with guitars is aerospace technology. Yet there is a connection. A whole family of quality guitars is an outgrowth of helicopter rotor research conducted for the military services and NASA by an aerospace contractor. These musical spinoffs, commercially available and rapidly gaining in popularity, are the Ovation guitar line, manufactured by Ovation Instruments, Inc., Bloomfield, Connecticut. Ovation Instruments is a subsidiary of Kaman Corporation, a diversified company originally formed to develop and build helicopters. A helicopter's rotor system, with thousands of moving parts, is highly susceptible to vibration. For rotor efficiency, vibration must be "dampened," or reduced. Like other helicopter builders, Kaman Corporation spent years of research toward that end. The technology thus developed, together with the availability of staff experts in vibration engineering, sparked an idea in the mind of the company's president and founder, Charles H. Karnan. A guitarist of professional caliber, Kaman reasoned that vibration-dampening technology could be turned around to enhance vibration and thereby produce a guitar with superior sound.

  9. SPIRE instrument for FIRST

    NASA Astrophysics Data System (ADS)

    Griffin, Matthew J.; Swinyard, Bruce M.; Vigroux, Laurent G.

    2000-07-01

    SPIRE, the Spectral and Photometric Imaging Receiver, will be a bolometer instrument for ESA's FIRST satellite. Its main scientific goals are deep extragalactic and galactic imaging surveys and spectroscopy of star-forming regions in own and nearby galaxies. The SPIRE detectors are feedhorn- coupled NTD spider-web bolometers. The instrument comprises a three-band imaging photometer covering the 250 - 500 micrometers range, and an imaging Fourier Transform Spectrometer (FTS) covering 200 - 670 micrometers . The photometer has a field of view of 4 X 8 arcminutes which is observed simultaneously at 250, 350 and 500 micrometers with dichroic beam dividers separating the three spectral bands. Its angular resolution is determined by the telescope diffraction limit, with FWHM beam widths of approximately 17, 24 and 35 arcseconds at 250, 350 and 500 micrometers , respectively. An internal beam steering mirror can be used for spatial modulation of the telescope beam, and observations can also be made by scanning the telescope without chopping, providing better sensitivity for source confusion-limited deep surveys. The FTS has a field of view of 2.6 arcminutes and an adjustable spectral resolution of 0.04 - 2 cm-1 ((lambda) /(Delta) (lambda) equals 20 - 1000 at 250 micrometers ). It employs a dual-beam configuration with novel broad-band intensity beam dividers to provide high efficiency and separated output and input ports.

  10. The QUIET Instrument

    NASA Technical Reports Server (NTRS)

    Gaier, T.; Kangaslahti, P.; Lawrence, C. R.; Leitch, E. M.; Wollack, E. J.

    2012-01-01

    The Q/U Imaging ExperimenT (QUIET) is designed to measure polarization in the Cosmic Microwave Background, targeting the imprint of inflationary gravitational waves at large angular scales ( approx 1 deg.) . Between 2008 October and 2010 December, two independent receiver arrays were deployed sequentially on a 1.4 m side-fed Dragonian telescope. The polarimeters which form the focal planes use a highly compact design based on High Electron Mobility Transistors (HEMTs) that provides simultaneous measurements of the Stokes parameters Q, U, and I in a single module. The 17-element Q-band polarimeter array, with a central frequency of 43.1 GHz, has the best sensitivity (69 micro Ks(exp 1/2)) and the lowest instrumental systematic errors ever achieved in this band, contributing to the tensor-to-scalar ratio at r < 0.1. The 84-element W-band polarimeter array has a sensitivity of 87 micro Ks(exp 1/2) at a central frequency of 94.5 GHz. It has the lowest systematic errors to date, contributing at r < 0.01 (QUIET Collaboration 2012) The two arrays together cover multipoles in the range l approximately equals 25-975 . These are the largest HEMT-ba.sed arrays deployed to date. This article describes the design, calibration, performance of, and sources of systematic error for the instrument,

  11. Space science instrumentation

    NASA Astrophysics Data System (ADS)

    Holzworth, R. H.

    1989-03-01

    This grant was intended to be used for the purchase of high quality laboratory and data analysis instrumentation for the pursuit of space plasma physics research. Two of the first purchases were a 6250 BPI magnetic tape drive and a large, fast disk drive. These improved the satellite data analysis capability greatly and reduced the system backup time. With the big disk drive it became possible to dump entire magnetic tapes to disk for faster, more efficient processing. Several microcomputers improve both personnel computing as well as general connectivity within the group and on campus in general. Other microcomputers function in the laboratory setting by acting as hosts for several instrument interfaces for communication with satellite and balloon payloads as well as laboratory VLF signal processing equipment. Perhaps the single most expensive item purchased was an analog tape drive for reading and writing 16 in. analog magnetic tapes. This analog tape drive is used for the direct processing of FM and directly recorded telemetry data from the balloon and rocket payloads.

  12. XEUS mission and instruments

    NASA Astrophysics Data System (ADS)

    Bavdaz, Marcos; Peacock, Anthony J.; Parmar, Arvind N.; Beijersbergen, Marco W.

    2002-01-01

    The X-ray Evolving Universe Spectroscopy mission (XEUS) is an ambitious project under study by the European Space Agency (ESA), which aims to probe the distant hot universe with comparable sensitivity to NGST and ALMA. The effective optical area and angular resolution required to perform this task is 30 m2 effective area and <5 inch angular resolution respectively at 1 keV. The single Wolter-I X-ray telescope having these characteristics will be equipped with large area semiconductor detectors and high-resolution cryogenic imaging spectrometers with 2 eV resolution at 1 keV. A novel approach to mission design has been developed, placing the detector instruments on one dedicated spacecraft and the optics on another. The International Space Station (ISS) with the best ever-available infrastructure in space will be used to expand the mirror diameter from 4.5 m to 10 m, by using the European Robotic Arm on the ISS. The detector spacecraft (DSC) uses solar-electric propulsion to maintain its position while flying in formation with the mirror spacecraft. The detector instruments are protected from straylight and contamination by sophisticated baffles and filters, and employing the Earth as a shield to make the most sensitive low energy X-ray observations of the heavily red-shifted universe. After completion of an initial observation phase lasting 5 years, the mirror spacecraft will be upgraded (basically expanded to a full 10 m diameter mirror) at the ISS, while the DSC is replaced by a new spacecraft with a new suite of detector instruments optimised to the full area XEUS mirror. An industrial feasibility study was successfully completed and identified no major problem area. Current activities focus on a full system level study and the necessary technology developments. XEUS is likely to become a truly global mission, involving many of the partners that have teamed up to build the ISS. Japan is already a major partner int the study of XEUS, with ISAS having its main

  13. Investigating the Mutagenicity of a Cold Argon-Plasma Jet in an HET-MN Model

    PubMed Central

    Bender, Claudia; Benkhai, Hicham; Sckell, Axel; Below, Harald; Stope, Matthias B.; Kramer, Axel

    2016-01-01

    Objective So-called cold physical plasmas for biomedical applications generate reactive oxygen and nitrogen species and the latter can trigger DNA damage at high concentrations. Therefore, the mutagenic risks of a certified atmospheric pressure argon plasma jet (kINPen MED) and its predecessor model (kINPen 09) were assessed. Methods Inner egg membranes of fertilized chicken eggs received a single treatment with either the kINPen 09 (1.5, 2.0, or 2.5 min) or the kINPen MED (3, 4, 5, or 10 min). After three days of incubation, blood smears (panoptic May-Grünwald-Giemsa stain) were performed, and 1000 erythrocytes per egg were evaluated for the presence of polychromatic and normochromic nuclear staining as well as nuclear aberrations and binucleated cells (hen’s egg test for micronuclei induction, HET-MN). At the same time, the embryo mortality was documented. For each experiment, positive controls (cyclophosphamide and methotrexate) and negative controls (NaCl-solution, argon gas) were included. Additionally, the antioxidant potential of the blood plasma was assessed by ascorbic acid oxidation assay after treatment. Results For both plasma sources, there was no evidence of genotoxicity, although at the longest plasma exposure time of 10 min the mortality of the embryos exceeded 40%. The antioxidant potential in the egg’s blood plasma was not significantly reduced immediately (p = 0.32) or 1 h (p = 0.19) post exposure to cold plasma. Conclusion The longest plasma treatment time with the kINPen MED was 5–10 fold above the recommended limit for treatment of chronic wounds in clinics. We did not find mutagenic effects for any plasma treatment time using the either kINPen 09 or kINPen MED. The data provided with the current study seem to confirm the lack of a genotoxic potential suggesting that a veterinary or clinical application of these argon plasma jets does not pose mutagenic risks. PMID:27584003

  14. Instrumented Pipeline Initiative

    SciTech Connect

    Thomas Piro; Michael Ream

    2010-07-31

    This report summarizes technical progress achieved during the cooperative agreement between Concurrent Technologies Corporation (CTC) and U.S. Department of Energy to address the need for a for low-cost monitoring and inspection sensor system as identified in the Department of Energy (DOE) National Gas Infrastructure Research & Development (R&D) Delivery Reliability Program Roadmap.. The Instrumented Pipeline Initiative (IPI) achieved the objective by researching technologies for the monitoring of pipeline delivery integrity, through a ubiquitous network of sensors and controllers to detect and diagnose incipient defects, leaks, and failures. This report is organized by tasks as detailed in the Statement of Project Objectives (SOPO). The sections all state the objective and approach before detailing results of work.

  15. Soldering instrument safety improvements

    SciTech Connect

    Kosslow, W.J.; Giron, R.W.

    1994-12-31

    It is an object of the present invention to make soldering instruments safer and easier to use. According to one aspect of the present invention, a non-heatsinking, protective shield is provided around the soldering tip of the solder iron. This heat shield covers the iron`s hot tip throughout the soldering process with the exception of the time needed to perform an actual solder connection using the tip. The shield protects the user or nearby personnel from harm when the soldering iron is at elevated temperatures (500{degrees}F to 800{degrees}F).Moreover, the shield is capable of preventing fires which might result if the iron`s tip inadvertently comes into contact with an object that can be easily ignited, e.g. paper. In addition, an air vacuum system is incorporated into the shield to remove the solder smoke.

  16. Portable musical instrument amplifier

    DOEpatents

    Christian, David E.

    1990-07-24

    The present invention relates to a musical instrument amplifier which is particularly useful for electric guitars. The amplifier has a rigid body for housing both the electronic system for amplifying and processing signals from the guitar and the system's power supply. An input plug connected to and projecting from the body is electrically coupled to the signal amplifying and processing system. When the plug is inserted into an output jack for an electric guitar, the body is rigidly carried by the guitar, and the guitar is operatively connected to the electrical amplifying and signal processing system without use of a loose interconnection cable. The amplifier is provided with an output jack, into which headphones are plugged to receive amplified signals from the guitar. By eliminating the conventional interconnection cable, the amplifier of the present invention can be used by musicians with increased flexibility and greater freedom of movement.

  17. Instrumentation Working Group Summary

    NASA Technical Reports Server (NTRS)

    Zaller, Michelle; Miake-Lye, Richard

    1999-01-01

    The Instrumentation Working Group compiled a summary of measurement techniques applicable to gas turbine engine aerosol precursors and particulates. An assessment was made of the limits, accuracy, applicability, and technology readiness of the various techniques. Despite advances made in emissions characterization of aircraft engines, uncertainties still exist in the mechanisms by which aerosols and particulates are produced in the near-field engine exhaust. To adequately assess current understanding of the formation of sulfuric acid aerosols in the exhaust plumes of gas turbine engines, measurements are required to determine the degree and importance of sulfur oxidation in the turbine and at the engine exit. Ideally, concentrations of all sulfur species would be acquired, with emphasis on SO2 and SO3. Numerous options exist for extractive and non-extractive measurement of SO2 at the engine exit, most of which are well developed. SO2 measurements should be performed first to place an upper bound on the percentage of SO2 oxidation. If extractive and non-extractive techniques indicate that a large amount of the fuel sulfur is not detected as SO2, then efforts are needed to improve techniques for SO3 measurements. Additional work will be required to account for the fuel sulfur in the engine exhaust. Chemical Ionization Mass Spectrometry (CI-MS) measurements need to be pursued, although a careful assessment needs to be made of the sampling line impact on the extracted sample composition. Efforts should also be placed on implementing non-intrusive techniques and extending their capabilities by maximizing exhaust coverage for line-of-sight measurements, as well as development of 2-D techniques, where feasible. Recommendations were made to continue engine exit and combustor measurements of particulates. Particulate measurements should include particle size distribution, mass fraction, hydration properties, and volatile fraction. However, methods to ensure that unaltered

  18. Reconfigurable laser ranging instrument

    NASA Astrophysics Data System (ADS)

    Schneiter, John

    1994-03-01

    This paper describes the design and operation of a fast, flexible, non-contact, eye-safe laser ranging instrument useful in a variety of industrial metrology situations, such as in-process machining control and part inspection. The system has variable computer-controlled standoff and depth of field, and can obtain 3-D images of surfaces within a range of from 1.5 ft to almost 10 ft from the final optical element. The minimum depth of field is about 3.5 in. at 1.5 ft and about 26 in. at the far range. The largest depth of field for which useful data are available is about 41 in. Resolution, with appropriate averaging, is about one part in 4000 of the depth of field, which implies a best case resolution for this prototype of 0.00075 in. System flexibility is achieved by computer controlled relative positioning of optical components.

  19. LANDSAT instruments characterization

    NASA Technical Reports Server (NTRS)

    Lee, Y. (Principal Investigator)

    1984-01-01

    Work performed for the LANDSAT instrument characterization task in the areas of absolute radiometry, coherent noise analysis, and between-date smoothing is reported. Absolute radiometric calibration for LANDSAT-5 TM under ambient conditions was performed. The TM Radiometric Algorithms and Performance Program (TRAPP) was modified to create optional midscan data files and to match the TM Image Processing System (TIPS) algorithm for pulse determination. Several data reduction programs were developed, including a linear regression and its plotted result. A fast Fourier transformation study was conducted on the resequenced TM data. Subscenes of homogeneous water within scenes over Pensacola, Florida were used for testing the FFT on the resequenced data. Finally, a gain and pulse height stability study of LANDSAT 5 TM spectral bands was performed.

  20. NEUTRONIC REACTOR CORE INSTRUMENT

    DOEpatents

    Mims, L.S.

    1961-08-22

    A multi-purpose instrument for measuring neutron flux, coolant flow rate, and coolant temperature in a nuclear reactor is described. The device consists essentially of a hollow thimble containing a heat conducting element protruding from the inner wall, the element containing on its innermost end an amount of fissionsble materinl to function as a heat source when subjected to neutron flux irradiation. Thermocouple type temperature sensing means are placed on the heat conducting element adjacent the fissionable material and at a point spaced therefrom, and at a point on the thimble which is in contact with the coolant fluid. The temperature differentials measured between the thermocouples are determinative of the neutron flux, coolant flow, and temperature being measured. The device may be utilized as a probe or may be incorporated in a reactor core. (AE C)

  1. Instrumented Architectural Simulation System

    NASA Technical Reports Server (NTRS)

    Delagi, B. A.; Saraiya, N.; Nishimura, S.; Byrd, G.

    1987-01-01

    Simulation of systems at an architectural level can offer an effective way to study critical design choices if (1) the performance of the simulator is adequate to examine designs executing significant code bodies, not just toy problems or small application fragements, (2) the details of the simulation include the critical details of the design, (3) the view of the design presented by the simulator instrumentation leads to useful insights on the problems with the design, and (4) there is enough flexibility in the simulation system so that the asking of unplanned questions is not suppressed by the weight of the mechanics involved in making changes either in the design or its measurement. A simulation system with these goals is described together with the approach to its implementation. Its application to the study of a particular class of multiprocessor hardware system architectures is illustrated.

  2. Ideology as instrument.

    PubMed

    Glassman, Michael; Karno, Donna

    2007-12-01

    Comments on the article by J. T. Jost, which argued that the end-of-ideology claims that emerged in the aftermath of World War II were both incorrect and detrimental to the field of political psychology. M. Glassman and D. Karno make three critical points. First, Jost objectified ideology as a grand strategy implemented at the individual level, rather than as an instrument used for a specific purpose in activity. In doing so, he set ideology up as an "object" that guides human behavior rather than as a rational part of human experience. Second, they take issue with the idea that, because somebody acts in a manner that can be categorized as ideological, there actually is such a thing as ideology separate from that event and/or political experience and that psychologists ought to understand the meaning of ideology in order to understand future human activities as outside observers. Third, Jost seems to see this objective ideology as a unidirectional, causal mechanism for activity, a mechanism that assumes individuals act according to ideology, which eclipses the possibility that immediate ideological positions are the residue of purposeful activity. Glassman and Karno suggest that it may be better to take a pluralistic view of ideology in human action. Where ideology does exist, it is as a purposeful instrument--part of a logically based action to meet some ends-in-view--a mixture of immediate goals tied to secondary belief systems (which have been integrated to serve the material purposes of the purveyors of these ideologies). So if we are to understand ideology, we can only understand it through its use in human activity. PMID:18085858

  3. HETDEX: Developing the HET's Second Generation Low Resolution Spectrograph for Probing Lyman-alpha Emitting Galaxies

    NASA Astrophysics Data System (ADS)

    Chonis, Taylor S.; Hill, G. J.; Lee, H.; Tuttle, S. E.; Vattiat, B. L.; Gebhardt, K.; Finkelstein, S. L.; Adams, J. J.; HETDEX Collaboration

    2012-01-01

    HETDEX will map the power spectrum of 0.8 million blindly discovered Lyman-alpha Emitting Galaxies (LAE) using a revolutionary new array of massively replicated fiber-fed spectrographs dubbed the Visible Integral-Field Replicable Unit Spectrograph (VIRUS). In the era of the Hobby-Eberly Telescope wide-field upgrade and VIRUS, the current Low Resolution Spectrograph (LRS) must be replaced with a fiber instrument. We discuss the development of the second generation LRS (LRS2), which is a multi-channel instrument based on the VIRUS design. In its current design phase, it is fed by a 287 fiber microlens coupled integral field unit that covers 7” x 12” with 0.62” resolution. The instrument covers 3720 Å to 4700 Å at R ≈ 1900 and 4600 Å to 7000 Å at R ≈1200. With the purpose of making the instrument ideal for follow-up observations of LAE in the HETDEX survey, we discuss the science drivers for selecting the instrument's spectral resolution. We test the utility of the instrument and pilot a future study with LRS2 by presenting R ≈ 2000 spectra taken with the VIRUS prototype spectrograph (VIRUS-P) in a high-resolution mode at the McDonald Observatory Harlan J. Smith 2.7 m telescope. These LAE were originally discovered in the HETDEX Pilot Survey and their Lyman-alpha line profiles are constrained by near-infrared observations of rest-frame optical emission lines that set the systemic redshift of the galaxies. We discuss the velocity offsets of the Lyman-alpha line from the systemic line center and compare the line profiles to theoretical predictions and to similar observations for Lyman-break galaxies. Our observations provide an example of how LRS2 can be used to probe Lyman-alpha emission in 2 < z < 3 star forming galaxies.

  4. Instrumentation and control systems, equipment location; instrumentation and control building, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Instrumentation and control systems, equipment location; instrumentation and control building, instrumentation room, bays and console plan. Specifications No. Eng-04-353-55-72; drawing no. 60-09-12; sheet 110 of 148; file no. 1321/61. Stamped: Record drawing - as constructed. Below stamp: Contract no. 4338, no change. - Edwards Air Force Base, Air Force Rocket Propulsion Laboratory, Control Center, Test Area 1-115, near Altair & Saturn Boulevards, Boron, Kern County, CA

  5. Virtual Instrument Simulator for CERES

    NASA Technical Reports Server (NTRS)

    Chapman, John J.

    1997-01-01

    A benchtop virtual instrument simulator for CERES (Clouds and the Earth's Radiant Energy System) has been built at NASA, Langley Research Center in Hampton, VA. The CERES instruments will fly on several earth orbiting platforms notably NASDA's Tropical Rainfall Measurement Mission (TRMM) and NASA's Earth Observing System (EOS) satellites. CERES measures top of the atmosphere radiative fluxes using microprocessor controlled scanning radiometers. The CERES Virtual Instrument Simulator consists of electronic circuitry identical to the flight unit's twin microprocessors and telemetry interface to the supporting spacecraft electronics and two personal computers (PC) connected to the I/O ports that control azimuth and elevation gimbals. Software consists of the unmodified TRW developed Flight Code and Ground Support Software which serves as the instrument monitor and NASA/TRW developed engineering models of the scanners. The CERES Instrument Simulator will serve as a testbed for testing of custom instrument commands intended to solve in-flight anomalies of the instruments which could arise during the CERES mission. One of the supporting computers supports the telemetry display which monitors the simulator microprocessors during the development and testing of custom instrument commands. The CERES engineering development software models have been modified to provide a virtual instrument running on a second supporting computer linked in real time to the instrument flight microprocessor control ports. The CERES Instrument Simulator will be used to verify memory uploads by the CERES Flight Operations TEAM at NASA. Plots of the virtual scanner models match the actual instrument scan plots. A high speed logic analyzer has been used to track the performance of the flight microprocessor. The concept of using an identical but non-flight qualified microprocessor and electronics ensemble linked to a virtual instrument with identical system software affords a relatively inexpensive

  6. The instrumental rationality of addiction.

    PubMed

    Pickard, Hanna

    2011-12-01

    The claim that non-addictive drug use is instrumental must be distinguished from the claim that its desired ends are evolutionarily adaptive or easy to comprehend. Use can be instrumental without being adaptive or comprehensible. This clarification, together with additional data, suggests that Müller & Schumann's (M&S's) instrumental framework may explain addictive, as well as non-addictive consumption. PMID:22074973

  7. Experimenting with string musical instruments

    NASA Astrophysics Data System (ADS)

    LoPresto, Michael C.

    2012-03-01

    What follows are several investigations involving string musical instruments developed for and used in a Science of Sound & Light course. The experiments make use of a guitar, orchestral string instruments and data collection and graphing software. They are designed to provide students with concrete examples of how mathematical formulae, when used in physics, represent reality that can actually be observed, in this case, the operation of string musical instruments.

  8. Two Radiative/Thermochemical Instruments

    NASA Technical Reports Server (NTRS)

    Tapphorn, Ralph M.; Janoff, Dwight D.; Shelley, Richard M.

    1990-01-01

    Measurements of absorption and emission complement thermal measurements. Two laboratory instruments for research in combustion and pyrolysis equipped for radiative as well as thermal measurements. One instrument essentially differential scanning calorimeter (DSC) modified to detect radiation emitted by flames. Provides means to evaluate limits of flammability of materials exhibiting exothermic reactions in DSC's. Other instrument used to determine pyrolysis properties of specimens exposed to various gases by measurement of infrared absorption spectra of pyrolysis products.

  9. HET0016, a Selective Inhibitor of 20-HETE Synthesis, Decreases Pro-Angiogenic Factors and Inhibits Growth of Triple Negative Breast Cancer in Mice

    PubMed Central

    Borin, Thaiz Ferraz; Zuccari, Debora A. P. C.; Jardim-Perassi, Bruna V.; Ferreira, Lívia C.; Iskander, A. S. M.; Varma, Nadimpalli Ravi S.; Shankar, Adarsh; Guo, Austin M.; Scicli, Guillermo; Arbab, Ali S.

    2014-01-01

    A selective inhibitor of 20-HETE synthesis, HET0016, has been reported to inhibit angiogenesis. 20-HETE has been known as a second mitogenic messenger of angiogenesis inducing growth factors. HET0016 effects were analyzed on MDA-MB-231 derived breast cancer in mouse and in vitro cell line. MDA-MB-231 tumor cells were implanted in animals’ right flank and randomly assigned to early (1 and 2), starting treatments on day 0, or delayed groups (3 and 4) on day 8 after implantation of tumor. Animals received HET0016 (10 mg/kg) treatment via intraperitoneal injection for 5 days/week for either 3 or 4 weeks. Control group received vehicle treatment. Tumor sizes were measured on days 7, 14, 21, and 28 and the animals were euthanized on day 22 and 29. Proteins were extracted from the whole tumor and from cells treated with 10 µM HET0016 for 4 and 24 hrs. Protein array kits of 20 different cytokines/factors were used. ELISA was performed to observe the HIF-1α and MMP-2 protein expression. Other markers were confirmed by IHC. HET0016 significantly inhibited tumor growth in all treatment groups at all-time points compared to control (p<0.05). Tumor growth was completely inhibited on three of ten animals on early treatment group. Treatment groups showed significantly lower expression of pro-angiogenic factors compared to control at 21 days; however, there was no significant difference in HIF-1α expression after treatments. Similar results were found in vitro at 24 hrs of HET0016 treatment. After 28 days, significant increase of angiogenin, angiopoietin-1/2, EGF-R and IGF-1 pro-angiogenic factors were found (p<0.05) compared to control, as well as an higher intensity of all factors were found when compared to that of 21 day’s data, suggesting a treatment resistance. HET0016 inhibited tumor growth by reducing expression of different set of pro-angiogenic factors; however, a resistance to treatment seemed to happen after 21 days. PMID:25549350

  10. The tissue diagnostic instrument.

    PubMed

    Hansma, Paul; Yu, Hongmei; Schultz, David; Rodriguez, Azucena; Yurtsev, Eugene A; Orr, Jessica; Tang, Simon; Miller, Jon; Wallace, Joseph; Zok, Frank; Li, Cheng; Souza, Richard; Proctor, Alexander; Brimer, Davis; Nogues-Solan, Xavier; Mellbovsky, Leonardo; Peña, M Jesus; Diez-Ferrer, Oriol; Mathews, Phillip; Randall, Connor; Kuo, Alfred; Chen, Carol; Peters, Mathilde; Kohn, David; Buckley, Jenni; Li, Xiaojuan; Pruitt, Lisa; Diez-Perez, Adolfo; Alliston, Tamara; Weaver, Valerie; Lotz, Jeffrey

    2009-05-01

    Tissue mechanical properties reflect extracellular matrix composition and organization, and as such, their changes can be a signature of disease. Examples of such diseases include intervertebral disk degeneration, cancer, atherosclerosis, osteoarthritis, osteoporosis, and tooth decay. Here we introduce the tissue diagnostic instrument (TDI), a device designed to probe the mechanical properties of normal and diseased soft and hard tissues not only in the laboratory but also in patients. The TDI can distinguish between the nucleus and the annulus of spinal disks, between young and degenerated cartilage, and between normal and cancerous mammary glands. It can quantify the elastic modulus and hardness of the wet dentin left in a cavity after excavation. It can perform an indentation test of bone tissue, quantifying the indentation depth increase and other mechanical parameters. With local anesthesia and disposable, sterile, probe assemblies, there has been neither pain nor complications in tests on patients. We anticipate that this unique device will facilitate research on many tissue systems in living organisms, including plants, leading to new insights into disease mechanisms and methods for their early detection.

  11. Detectors for Tomorrow's Instruments

    NASA Technical Reports Server (NTRS)

    Moseley, Harvey

    2009-01-01

    Cryogenically cooled superconducting detectors have become essential tools for a wide range of measurement applications, ranging from quantum limited heterodyne detection in the millimeter range to direct searches for dark matter with superconducting phonon detectors operating at 20 mK. Superconducting detectors have several fundamental and practical advantages which have resulted in their rapid adoption by experimenters. Their excellent performance arises in part from reductions in noise resulting from their low operating temperatures, but unique superconducting properties provide a wide range of mechanisms for detection. For example, the steep dependence of resistance with temperature on the superconductor/normal transition provides a sensitive thermometer for calorimetric and bolometric applications. Parametric changes in the properties of superconducting resonators provides a mechanism for high sensitivity detection of submillimeter photons. From a practical point of view, the use of superconducting detectors has grown rapidly because many of these devices couple well to SQUID amplifiers, which are easily integrated with the detectors. These SQUID-based amplifiers and multiplexers have matured with the detectors; they are convenient to use, and have excellent noise performance. The first generation of fully integrated large scale superconducting detection systems are now being deployed. I will discuss the prospects for a new generation of instruments designed to take full advantage of the revolution in detector technology.

  12. The tissue diagnostic instrument

    PubMed Central

    Hansma, Paul; Yu, Hongmei; Schultz, David; Rodriguez, Azucena; Yurtsev, Eugene A.; Orr, Jessica; Tang, Simon; Miller, Jon; Wallace, Joseph; Zok, Frank; Li, Cheng; Souza, Richard; Proctor, Alexander; Brimer, Davis; Nogues-Solan, Xavier; Mellbovsky, Leonardo; Peña, M. Jesus; Diez-Ferrer, Oriol; Mathews, Phillip; Randall, Connor; Kuo, Alfred; Chen, Carol; Peters, Mathilde; Kohn, David; Buckley, Jenni; Li, Xiaojuan; Pruitt, Lisa; Diez-Perez, Adolfo; Alliston, Tamara; Weaver, Valerie; Lotz, Jeffrey

    2009-01-01

    Tissue mechanical properties reflect extracellular matrix composition and organization, and as such, their changes can be a signature of disease. Examples of such diseases include intervertebral disk degeneration, cancer, atherosclerosis, osteoarthritis, osteoporosis, and tooth decay. Here we introduce the tissue diagnostic instrument (TDI), a device designed to probe the mechanical properties of normal and diseased soft and hard tissues not only in the laboratory but also in patients. The TDI can distinguish between the nucleus and the annulus of spinal disks, between young and degenerated cartilage, and between normal and cancerous mammary glands. It can quantify the elastic modulus and hardness of the wet dentin left in a cavity after excavation. It can perform an indentation test of bone tissue, quantifying the indentation depth increase and other mechanical parameters. With local anesthesia and disposable, sterile, probe assemblies, there has been neither pain nor complications in tests on patients. We anticipate that this unique device will facilitate research on many tissue systems in living organisms, including plants, leading to new insights into disease mechanisms and methods for their early detection. PMID:19485522

  13. Halo vest instrumentation

    NASA Astrophysics Data System (ADS)

    Huston, Dryver R.; Krag, Martin

    1996-05-01

    The halo vest is a head and neck immobilization system that is often used on patients that are recovering from cervical trauma or surgery. The halo vest system consists of a rigid halo that is firmly attached to the skull, an upright support structure for stabilization and immobilization, and a torso-enveloping vest. The main purpose of this study was to measure the forces that are carried by the halo-vest structure as the subject undergoes various activities of daily living and external loading for different vest designs. A tethered strain gage load cell based instrumentation system was used to take these load measurements on ten different subjects. Three different halo-vest systems were evaluated. The primary difference between the vests was the amount of torso coverage and the use of shoulder straps. The loads were measured, analyzed and used to compare the vests and to create a model of halo-vest-neck mechanics. Future applications of this technology to standalone data logging, pin-load measuring and biofeedback applications are discussed.

  14. Instrumentation Working Group Summary

    NASA Technical Reports Server (NTRS)

    Zaller, Michelle; Miake-Lye, Richard

    1999-01-01

    The Instrumentation Working Group compiled a summary of measurement techniques applicable to gas turbine engine aerosol precursors and particulates. An assessment was made of the limits, accuracy, applicability, and technology readiness of the various techniques. Despite advances made in emissions characterization of aircraft engines, uncertainties still exist in the mechanisms by which aerosols and particulates are produced in the near-field engine exhaust. To adequately assess current understanding of the formation of sulfuric acid aerosols in the exhaust plumes of gas turbine engines, measurements are required to determine the degree and importance of sulfur oxidation in the turbine and at the engine exit. Ideally, concentrations of all sulfur species would be acquired, with emphasis on SO2 and SO3. Numerous options exist for extractive and non-extractive measurement of SO2 at the engine exit, most of which are well developed. SO2 measurements should be performed first to place an upper bound on the percentage of SO2 oxidation. If extractive and non-extractive techniques indicate that a large amount of the fuel sulfur is not detected as SO2, then efforts are needed to improve techniques for SO3 measurements. Additional work will be required to account for the fuel sulfur in the engine exhaust. Chemical Ionization Mass Spectrometry (CI-MS) measurements need to be pursued, although a careful assessment needs to be made of the sampling line impact on the extracted sample composition. Efforts should also be placed on implementing non-intrusive techniques and extending their capabilities by maximizing exhaust coverage for line-of-sight measurements, as well as development of 2-D techniques, where feasible. Recommendations were made to continue engine exit and combustor measurements of particulates. Particulate measurements should include particle size distribution, mass fraction, hydration properties, and volatile fraction. However, methods to ensure that unaltered

  15. The tissue diagnostic instrument

    NASA Astrophysics Data System (ADS)

    Hansma, Paul; Yu, Hongmei; Schultz, David; Rodriguez, Azucena; Yurtsev, Eugene A.; Orr, Jessica; Tang, Simon; Miller, Jon; Wallace, Joseph; Zok, Frank; Li, Cheng; Souza, Richard; Proctor, Alexander; Brimer, Davis; Nogues-Solan, Xavier; Mellbovsky, Leonardo; Peña, M. Jesus; Diez-Ferrer, Oriol; Mathews, Phillip; Randall, Connor; Kuo, Alfred; Chen, Carol; Peters, Mathilde; Kohn, David; Buckley, Jenni; Li, Xiaojuan; Pruitt, Lisa; Diez-Perez, Adolfo; Alliston, Tamara; Weaver, Valerie; Lotz, Jeffrey

    2009-05-01

    Tissue mechanical properties reflect extracellular matrix composition and organization, and as such, their changes can be a signature of disease. Examples of such diseases include intervertebral disk degeneration, cancer, atherosclerosis, osteoarthritis, osteoporosis, and tooth decay. Here we introduce the tissue diagnostic instrument (TDI), a device designed to probe the mechanical properties of normal and diseased soft and hard tissues not only in the laboratory but also in patients. The TDI can distinguish between the nucleus and the annulus of spinal disks, between young and degenerated cartilage, and between normal and cancerous mammary glands. It can quantify the elastic modulus and hardness of the wet dentin left in a cavity after excavation. It can perform an indentation test of bone tissue, quantifying the indentation depth increase and other mechanical parameters. With local anesthesia and disposable, sterile, probe assemblies, there has been neither pain nor complications in tests on patients. We anticipate that this unique device will facilitate research on many tissue systems in living organisms, including plants, leading to new insights into disease mechanisms and methods for their early detection.

  16. Ultrasonics and space instrumentation

    NASA Technical Reports Server (NTRS)

    1987-01-01

    The design topic selected was an outgrowth of the experimental design work done in the Fluid Behavior in Space experiment, which relies on the measurement of minute changes of the pressure and temperature to obtain reasonably accurate volume determinations. An alternative method of volume determination is the use of ultrasonic imaging. An ultrasonic wave system is generated by wall mounted transducer arrays. The interior liquid configuration causes reflection and refraction of the pattern so that analysis of the received wave system provides a description of the configuration and hence volume. Both continuous and chirp probe beams were used in a laboratory experiment simulating a surface wetting propellant. The hardware included a simulated tank with gaseous voids, transmitting and receiving transducers, transmitters, receivers, computer interface, and computer. Analysis software was developed for image generation and interpretation of results. Space instrumentation was pursued in support of a number of experiments under development for GAS flights. The program included thirty undergraduate students pursuing major qualifying project work under the guidance of eight faculty supported by a teaching assistant. Both mechanical and electrical engineering students designed and built several microprocessor systems to measure parameters such as temperature, acceleration, pressure, velocity, and circulation in order to determine combustion products, vortex formation, gas entrainment, EMR emissions from thunderstorms, and milli-g-accelerations due to crew motions.

  17. The Clementine instrument complement

    NASA Technical Reports Server (NTRS)

    Lucey, Paul G.

    1993-01-01

    The recent successes of the Galileo solid-state imaging (SSI) experiment at the Moon and Gaspra show the utility of multispectral imaging of planetary objects. 'Clementine' is the planetary community's 'code name' for the SDIO (Space Defense Initiative Organization), mission to the Moon and the asteroid Geographos. This mission is designed as a long term stressing test on sensors and space systems developed for SDIO. In the course of this test Clementine will obtain science data using a varied and powerful array of remote sensing instruments which were developed by or for Lawrence Livermore National Laboratory in Livermore, California. Clementine carries five cameras, one for navigation and four for science experiments. In addition, a laser ranger is included which will serve as a laser altimeter. The Clementine cameras cover a wider range of spatial resolutions and wavelength range than did Galileo and are almost ideally suited to mapping of mafic rock types as are present on the Moon and expected at Geographos. Calibration of the cameras will occur at the sensor calibration laboratory at LLNL. In flight calibrations, using standard stars and other standards should improve the stated accuracies. Signal-to-noise ratios (SNRs) include the following noise sources: shot noise, calibration error, digitization noise, readout noise, and frame transfer noise (where applicable). The achieved SNRs are a balance between detector saturation and acceptable image smear. The 'worst' case uses the longest possible integration times.

  18. Guideline implementation: surgical instrument cleaning.

    PubMed

    Cowperthwaite, Liz; Holm, Rebecca L

    2015-05-01

    Cleaning, decontaminating, and handling instructions for instruments vary widely based on the type of instrument and the manufacturer. Processing instruments in accordance with the manufacturer's instructions can help prevent damage and keep devices in good working order. Most importantly, proper cleaning and disinfection may prevent transmission of pathogenic organisms from a contaminated device to a patient or health care worker. The updated AORN "Guideline for cleaning and care of surgical instruments" provides guidance on cleaning, decontaminating, transporting, inspecting, and storing instruments. This article focuses on key points of the guideline to help perioperative personnel implement appropriate instrument care protocols in their practice settings. The key points address timely cleaning and decontamination of instruments after use; appropriate heating, ventilation, and air conditioning parameters for the decontamination area; processing of ophthalmic instruments and laryngoscopes; and precautions to take with instruments used in cases of suspected prion disease. Perioperative RNs should review the complete guideline for additional information and for guidance when writing and updating policies and procedures. PMID:25946180

  19. Guideline implementation: surgical instrument cleaning.

    PubMed

    Cowperthwaite, Liz; Holm, Rebecca L

    2015-05-01

    Cleaning, decontaminating, and handling instructions for instruments vary widely based on the type of instrument and the manufacturer. Processing instruments in accordance with the manufacturer's instructions can help prevent damage and keep devices in good working order. Most importantly, proper cleaning and disinfection may prevent transmission of pathogenic organisms from a contaminated device to a patient or health care worker. The updated AORN "Guideline for cleaning and care of surgical instruments" provides guidance on cleaning, decontaminating, transporting, inspecting, and storing instruments. This article focuses on key points of the guideline to help perioperative personnel implement appropriate instrument care protocols in their practice settings. The key points address timely cleaning and decontamination of instruments after use; appropriate heating, ventilation, and air conditioning parameters for the decontamination area; processing of ophthalmic instruments and laryngoscopes; and precautions to take with instruments used in cases of suspected prion disease. Perioperative RNs should review the complete guideline for additional information and for guidance when writing and updating policies and procedures.

  20. Spacecraft instrument technology and cosmochemistry.

    PubMed

    McSween, Harry Y; McNutt, Ralph L; Prettyman, Thomas H

    2011-11-29

    Measurements by instruments on spacecraft have significantly advanced cosmochemistry. Spacecraft missions impose serious limitations on instrument volume, mass, and power, so adaptation of laboratory instruments drives technology. We describe three examples of flight instruments that collected cosmochemical data. Element analyses by Alpha Particle X-ray Spectrometers on the Mars Exploration Rovers have revealed the nature of volcanic rocks and sedimentary deposits on Mars. The Gamma Ray Spectrometer on the Lunar Prospector orbiter provided a global database of element abundances that resulted in a new understanding of the Moon's crust. The Ion and Neutral Mass Spectrometer on Cassini has analyzed the chemical compositions of the atmosphere of Titan and active plumes on Enceladus.

  1. MISR Instrument Data Visualization

    NASA Technical Reports Server (NTRS)

    Nelson, David; Garay, Michael; Diner, David; Thompson, Charles; Hall, Jeffrey; Rheingans, Brian; Mazzoni, Dominic

    2008-01-01

    The MISR Interactive eXplorer (MINX) software functions both as a general-purpose tool to visualize Multiangle Imaging SpectroRadiometer (MISR) instrument data, and as a specialized tool to analyze properties of smoke, dust, and volcanic plumes. It includes high-level options to create map views of MISR orbit locations; scrollable, single-camera RGB (red-greenblue) images of MISR level 1B2 (L1B2) radiance data; and animations of the nine MISR camera images that provide a 3D perspective of the scenes that MISR has acquired. NASA Tech Briefs, September 2008 55 The plume height capability provides an accurate estimate of the injection height of plumes that is needed by air quality and climate modelers. MISR provides global high-quality stereo height information, and this program uses that information to perform detailed height retrievals of aerosol plumes. Users can interactively digitize smoke, dust, or volcanic plumes and automatically retrieve heights and winds, and can also archive MISR albedos and aerosol properties, as well as fire power and brightness temperatures associated with smoke plumes derived from Moderate Resolution Imaging Spectroradiometer (MODIS) data. Some of the specialized options in MINX enable the user to do other tasks. Users can display plots of top-of-atmosphere bidirectional reflectance factors (BRFs) versus camera-angle for selected pixels. Images and animations can be saved to disk in various formats. Also, users can apply a geometric registration correction to warp camera images when the standard processing correction is inadequate. It is possible to difference the images of two MISR orbits that share a path (identical ground track), as well as to construct pseudo-color images by assigning different combinations of MISR channels (angle or spectral band) to the RGB display channels. This software is an interactive application written in IDL and compiled into an IDL Virtual Machine (VM) ".sav" file.

  2. HETDEX: Overview of the Hobby-Eberly Telescope Dark Energy Experiment and Instrumentation

    NASA Astrophysics Data System (ADS)

    Hill, Gary J.; Gebhardt, K.; Drory, N.; DePoy, D.; Komatsu, E.; Bender, R.; Schneider, D.; Fabricius, M.; Lee, H.; Tuttle, S.; Marshall, J.; Kelz, A.; Roth, M.; Cornell, M.; HETDEX Collaboration

    2012-01-01

    The Hobby-Eberly Telescope Dark Energy Experiment (HETDEX) is a blind spectroscopic survey to map the evolution of dark energy using Lyman-alpha emitting galaxies as tracers. HETDEX comprises a major upgrade of the HET, deployment of the massively replicated integral field spectrograph, VIRUS, and the execution of a multi-year blind spectroscopic survey. VIRUS, consists of 75 IFUs distributed across the 22-arcmin field of the upgraded 9.2-m HET. Each 50x50 sq. arcsec IFU is made up of 448 1.5-arcsec fibers, and feeds a pair of spectrographs with a fixed bandpass of 350-550 nm and resolving power R 700. Each exposure gathers 33,600 spectra. Observing 20 minutes per field, we reach a line flux limit of 3.5e-17 ergs-sec-1-cm-2 and mAB 22. The baseline survey will deliver spectra of 0.8M LAEs in a 9 cubic Gpc volume with 1.9 < z < 3.5, and 1M [OII] emitters with z < 0.48. In addition, the survey will cover 0.4M other galaxies, 0.25M stars, 2000 galaxy clusters, 7000 QSOs with z < 3.5, and 20,000 NVSS radio sources. The main survey area of 42x7 sq. deg. is centered at 13hr, +53deg. Within that 300 sq. deg. region we cover 1/4.5 with fibers; thus 60 sq. deg. of sky have spectra. Initial observations will be conducted from Spring 2013 through Spring 2015. We present an overview of the project, including instrumentation and details of the planned surveys.

  3. Associations in Human Instrumental Conditioning

    ERIC Educational Resources Information Center

    Gamez, A. Matias; Rosas, Juan M.

    2007-01-01

    Four experiments were conducted to study the contents of human instrumental conditioning. Experiment 1 found positive transfer between a discriminative stimulus (S[superscript D] and an instrumental response (R) that shared the outcome (O) with the response that was originally trained with the S[superscript D], showing the formation of an…

  4. Zach's instruments and their characteristics

    NASA Astrophysics Data System (ADS)

    Wolfschmidt, Gudrun

    The astronomically interested Duke Ernst II von Sachsen-Gotha-Altenburg (1745-1804) hired Baron Franz Xaver von Zach (1754-1832) as court astronomer in 1786. Immediatedly Zach started to make plans for instrumentation for a new observatory. But first they travelled with their instruments (a 2-foot Ramsden transit instrument, the Sisson quadrant, three Hadley sextants, two achromatic refractors and chronometers) to southern France. In Hyàres a tower of the wall around the town was converted into an observatory in 1787. For the building of the new observatory Zach had chosen a place outside of Gotha on the top of the Seeberg. The three main instruments were an 8-foot transit instrument made by Ramsden, a northern and southern mural quadrant made by Sisson and a zenith sector made by Cary, in addition an 8-foot circle made by Ramsden. By analysing the whole instrumentation of Gotha observatory, we can see a change around 1800 in the kind of instruments, from quadrants and sextants to the full circles and from the transit instrument to the meridian circle. The decline of the Gotha observatory started with the early death of the Duke in 1804 and the subsequent departure of Zach in 1806.

  5. Usability in space science instrumentation

    NASA Astrophysics Data System (ADS)

    Bastien, J.; Scapin, D.

    2009-12-01

    The scientists who will eventually use data from a space instrument may not be the most important people to consider during the development programme, argues Alec McCalden. Better results could come from treating instrument usability as a design parameter from the start.

  6. Experimenting with String Musical Instruments

    ERIC Educational Resources Information Center

    LoPresto, Michael C.

    2012-01-01

    What follows are several investigations involving string musical instruments developed for and used in a "Science of Sound & Light" course. The experiments make use of a guitar, orchestral string instruments and data collection and graphing software. They are designed to provide students with concrete examples of how mathematical formulae, when…

  7. Technician Program Uses Advanced Instruments.

    ERIC Educational Resources Information Center

    Stinson, Stephen

    1981-01-01

    Describes various aspects of a newly-developed computer-assisted drafting/computer-assisted manufacture (CAD/CAM) facility in the chemical engineering technology department at Broome Community College, Binghamton, New York. Stresses the use of new instruments such as microcomputers and microprocessor-equipped instruments. (CS)

  8. Cryogenic Caging for Science Instrumentation

    NASA Technical Reports Server (NTRS)

    Penanen, Konstantin; Chui, Talso C.

    2011-01-01

    A method has been developed for caging science instrumentation to protect from pyro-shock and EDL (entry, descent, and landing) acceleration damage. Caging can be achieved by immersing the instrument (or its critical parts) in a liquid and solidifying the liquid by cooling. After the launch shock and/or after the payload has landed, the solid is heated up and evaporated.

  9. Introduction to Instrumentation. Teacher Edition.

    ERIC Educational Resources Information Center

    Brown, A. O., III

    This module contains instructional materials on instrumentation to help teachers train students in the job skills they will need as beginning instrumentation technicians. The module addresses the nature of accessing, measuring, and controlling phenomena such as level, flow, pressure, and temperature. Students are introduced to the devices and…

  10. Ethnic Studies Materials Analysis Instrument.

    ERIC Educational Resources Information Center

    Social Science Education Consortium, Inc., Boulder, CO.

    An instrument for analyzing ethnic studies curriculum materials for grades K-12 is presented. The Social Science Education Consortium (SSEC), Inc. staff designed the analysis instrument to check ethnic accuracy of materials as an aid to classroom teachers who are preparing ethnic studies curriculum. The booklet is divided into two main sections.…

  11. Career Education Materials Analysis Instrument.

    ERIC Educational Resources Information Center

    Hedstrom, Judith E.; Williams, Constance M.

    An instrument for analyzing career education curriculum materials for grades K-12 is presented. The Social Science Education Consortium (SSEC), Inc. staff designed the analysis instrument to check the educational soundness and accuracy of career education materials. The booklet is divided into two main sections. Part I is a modified version of the…

  12. The ATST Virtual Instrument Model

    NASA Astrophysics Data System (ADS)

    Wampler, S.; Goodrich, B.

    2004-07-01

    The Advanced Technology Solar Telescope (ATST) is intended to be the premier solar observatory for experimental physics. Unlike its night-time counterparts that operate with relatively fixed instrument sets, ATST's science goals and requirements are best met by a laboratory style instrument configuration, where scientific requirements often mean that instrumentation must be assembled by scientists to meet the unique demands of each experiment. In order to maximize observing efficiency the ATST software and control systems must be designed to operate smoothly in this environment. To meet the requirement of providing flexibility in a laboratory style operations environment, the control system uses a Virtual Instrument Model. This report introduces this model and briefly outlines its salient characteristics. The aim is to provide some insight into the approach being proposed as part of the overall software and controls design and to provide a foundation for discussions on the advantages and disadvantages of using a virtual instrument model.

  13. Instrument Remote Control Application Framework

    NASA Technical Reports Server (NTRS)

    Ames, Troy; Hostetter, Carl F.

    2006-01-01

    The Instrument Remote Control (IRC) architecture is a flexible, platform-independent application framework that is well suited for the control and monitoring of remote devices and sensors. IRC enables significant savings in development costs by utilizing extensible Markup Language (XML) descriptions to configure the framework for a specific application. The Instrument Markup Language (IML) is used to describe the commands used by an instrument, the data streams produced, the rules for formatting commands and parsing the data, and the method of communication. Often no custom code is needed to communicate with a new instrument or device. An IRC instance can advertise and publish a description about a device or subscribe to another device's description on a network. This simple capability of dynamically publishing and subscribing to interfaces enables a very flexible, self-adapting architecture for monitoring and control of complex instruments in diverse environments.

  14. Instrumental variables and Mendelian randomization with invalid instruments

    NASA Astrophysics Data System (ADS)

    Kang, Hyunseung

    Instrumental variables (IV) methods have been widely used to determine the causal effect of a treatment, exposure, policy, or an intervention on an outcome of interest. The IV method relies on having a valid instrument, a variable that is (A1) associated with the exposure, (A2) has no direct effect on the outcome, and (A3) is unrelated to the unmeasured confounders associated with the exposure and the outcome. However, in practice, finding a valid instrument, especially those that satisfy (A2) and (A3), can be challenging. For example, in Mendelian randomization studies where genetic markers are used as instruments, complete knowledge about instruments' validity is equivalent to complete knowledge about the involved genes' functions. The dissertation explores the theory, methods, and application of IV methods when invalid instruments are present. First, when we have multiple candidate instruments, we establish a theoretical bound whereby causal effects are only identified as long as less than 50% of instruments are invalid, without knowing which of the instruments are invalid. We also propose a fast penalized method, called sisVIVE, to estimate the causal effect. We find that sisVIVE outperforms traditional IV methods when invalid instruments are present both in simulation studies as well as in real data analysis. Second, we propose a robust confidence interval under the multiple invalid IV setting. This work is an extension of our work on sisVIVE. However, unlike sisVIVE which is robust to violations of (A2) and (A3), our confidence interval procedure provides honest coverage even if all three assumptions, (A1)-(A3), are violated. Third, we study the single IV setting where the one IV we have may actually be invalid. We propose a nonparametric IV estimation method based on full matching, a technique popular in causal inference for observational data, that leverages observed covariates to make the instrument more valid. We propose an estimator along with

  15. GEO Sounding Using Microwave Instruments

    NASA Technical Reports Server (NTRS)

    Shiue, James; Krimchansky, Sergey; Susskind, Joel; Krimchansky, Alexander; Chu, Donald; Davis, Martin

    2004-01-01

    There are several microwave instruments in low Earth orbit (LEO) that are used for atmospheric temperature and humidity sounding in conjunction with companion IR sounders as well as by themselves. These instruments have achieved a certain degree of maturity and undergoing a redesign to minimize their size, mass, and power from the previous generation instruments. An example of these instruments is the AMSU-A series, now flying on POES and AQUA spacecraft with the IR sounders HIRS and AIRS. These older microwave instruments are going to be replaced by the ATMS instruments that will fly on NPP and NPOESS satellites with the CrIS sounder. A number of techniques learned from the ATMS project in instrument hardware design and data processing are directly applicable to a similar microwave sounder on a geosynchronous platform. These techniques can significantly simplify the design of a Geostationary orbit (GEO) microwave instrument, avoiding costly development and minimizing the risk of not being able to meet the scientific requirements. In fact, some of the 'enabling' technology, such as the use of MMIC microwave components (which is the basis for the ATMS' much reduced volume) can be directly applied to a GEO sounder. The benefits of microwave sounders are well known; for example, they penetrate non-precipitating cloud cover and allow for use of colocated IR observations in up to 80% cloud cover. The key advantages of a microwave instrument in GEO will be the ability to provide high temporal resolution as well as uniform spatial resolution and extend the utility of a colocated advanced IR sounder to cases in which partial cloud cover exists. A footprint of the order of 100 km by 100 km resolution with hemispherical coverage within one hour can be easily achieved for sounding channels in the 50 to 59 GHz range. A GEO microwave sounder will also allow mesoscale sampling of select regions.

  16. Novel fiber optic immunosensor instrument

    NASA Astrophysics Data System (ADS)

    Wang, Zhiyu; Huang, Wenling; Tang, Lei; Zhou, Bo; Li, Yugi; He, Jun

    1996-09-01

    It has developed and performed a novel fiberoptic immunosensor instrument with operating wavelength 400 - 760 nm and repeatability cv equals 0.27%. The instrument has many excellent features such as simplified operation, faster testing time, higher sensitivity and economic cost. It has completely eliminated recovery period which traditional immunosensor owned due to use separative sensor structure. It can widely apply to test for bacteria, virus, hormone, parasite and cancer protein in clinical examination. The instrument has operated in laboratory and relevant medicine units and successfully tested monoclonal rat-anti-human of 413 cases in clinic and prepared with existing ELISA method, the coincidence probability reached 94 to 100%.

  17. Commissioning Instrument for the GTC

    NASA Astrophysics Data System (ADS)

    Cuevas, S.; Sánchez, B.; Bringas, V.; Espejo, C.; Flores, R.; Chapa, O.; Lara, G.; Chavolla, A.; Anguiano, G.; Arciniega, S.; Dorantes, A.; González, J. L.; Montoya, J. M.; Toral, R.; Hernández, H.; Nava, R.; Devaney, N.; Castro, J.; Cavaller-Marqués, L.

    2005-12-01

    During the GTC integration phase, the Commissioning Instrument (CI) will be a diagnostic tool for performance verification. The CI features four operation modes: imaging, pupil imaging, Curvature WFS, and high resolution Shack-Hartmann WFS. This instrument was built by the Instituto de Astronomía UNAM and the Centro de Ingeniería y Desarrollo Industrial (CIDESI) under GRANTECAN contract after a public bid. In this paper we made a general instrument overview and we show some of the performance final results obtained when the Factory Acceptance tests previous to its transport to La Palma.

  18. Foundations of measurement and instrumentation

    NASA Technical Reports Server (NTRS)

    Warshawsky, Isidore

    1990-01-01

    The user of instrumentation has provided an understanding of the factors that influence instrument performance, selection, and application, and of the methods of interpreting and presenting the results of measurements. Such understanding is prerequisite to the successful attainment of the best compromise among reliability, accuracy, speed, cost, and importance of the measurement operation in achieving the ultimate goal of a project. Some subjects covered are dimensions; units; sources of measurement error; methods of describing and estimating accuracy; deduction and presentation of results through empirical equations, including the method of least squares; experimental and analytical methods of determining the static and dynamic behavior of instrumentation systems, including the use of analogs.

  19. Adjustable extender for instrument module

    DOEpatents

    Sevec, J.B.; Stein, A.D.

    1975-11-01

    A blank extender module used to mount an instrument module in front of its console for repair or test purposes has been equipped with a rotatable mount and means for locking the mount at various angles of rotation for easy accessibility. The rotatable mount includes a horizontal conduit supported by bearings within the blank module. The conduit is spring-biased in a retracted position within the blank module and in this position a small gear mounted on the conduit periphery is locked by a fixed pawl. The conduit and instrument mount can be pulled into an extended position with the gear clearing the pawl to permit rotation and adjustment of the instrument.

  20. Validating GOES Instrument Thermal Deformations

    NASA Technical Reports Server (NTRS)

    Harter, Peter; Ghaffarian, Benny; Ng, Ray; Pugh, Brett; Wilkin, Paul; Sayal, Chetan; Chu, Don

    2001-01-01

    Comparison of the Geostationary Operational Environmental Satellite (GOES) instrument thermal model predictions with on-orbit data shows that the models capture the observed temperature and misalignment trends. Lack of precise knowledge as to spacecraft pointing precludes such comparison with instrument pointing predictions. Based on the models, thermally induced instrument attitude variation will dominate GOES N-Q Image Motion Compensation (IMC). Errors due to day-to-day changes in the attitude profiles are predicted to be under 10 microradians except for rapid scans where disturbances may reach 30 microradians.

  1. Genetic markers as instrumental variables

    PubMed Central

    von Hinke, Stephanie; Davey Smith, George; Lawlor, Debbie A.; Propper, Carol; Windmeijer, Frank

    2016-01-01

    The use of genetic markers as instrumental variables (IV) is receiving increasing attention from economists, statisticians, epidemiologists and social scientists. Although IV is commonly used in economics, the appropriate conditions for the use of genetic variants as instruments have not been well defined. The increasing availability of biomedical data, however, makes understanding of these conditions crucial to the successful use of genotypes as instruments. We combine the econometric IV literature with that from genetic epidemiology, and discuss the biological conditions and IV assumptions within the statistical potential outcomes framework. We review this in the context of two illustrative applications. PMID:26614692

  2. Ames Scientists Develop MSL Instrument

    NASA Video Gallery

    David Blake, a research scientist at NASA Ames, led the development of CheMin, one of ten scientific instruments onboard Curiosity, the Mars Scientific Laboratory. The Powder X-Ray Diffraction tool...

  3. Instrumentation for Air Pollution Monitoring

    ERIC Educational Resources Information Center

    Hollowell, Craig D.; McLaughlin, Ralph D.

    1973-01-01

    Describes the techniques which form the basis of current commercial instrumentation for monitoring five major gaseous atmospheric pollutants (sulfur dioxide, oxides of nitrogen, oxidants, carbon monoxide, and hydrocarbons). (JR)

  4. Instrument detects bacterial life forms

    NASA Technical Reports Server (NTRS)

    Plakas, C.

    1971-01-01

    Instrument assays enzymatic bioluminescent reaction that occurs when adenosine triphosphate /ATP/ combines with lucifrase and luciferin. Module assembly minimizes need for hardware associated with reaction fluid and waste transfer. System is applicable in marine biology and aerospace and medical fields.

  5. Islamic Astronomical Instruments and Observatories

    NASA Astrophysics Data System (ADS)

    Heidarzadeh, Tofigh

    This chapter is a brief survey of astronomical instruments being used and developed in Islamic territories from the eighth to the fifteenth centuries as well as a concise account of major observatories and observational programs in this period.

  6. Tailoring Instrumentation to the Operator.

    ERIC Educational Resources Information Center

    Abplanalp, Glen H.; Menzenhauer, Fred C.

    1978-01-01

    This article provides guidelines in selecting appropriate instrumentation for water treatment facilities. Major areas of concern include: technical operating requirements of the process; equipment design and quality; installations; and mechanical aptitude of personnel. (CS)

  7. Spacecraft instrument technology and cosmochemistry

    PubMed Central

    McSween, Harry Y.; McNutt, Ralph L.; Prettyman, Thomas H.

    2011-01-01

    Measurements by instruments on spacecraft have significantly advanced cosmochemistry. Spacecraft missions impose serious limitations on instrument volume, mass, and power, so adaptation of laboratory instruments drives technology. We describe three examples of flight instruments that collected cosmochemical data. Element analyses by Alpha Particle X-ray Spectrometers on the Mars Exploration Rovers have revealed the nature of volcanic rocks and sedimentary deposits on Mars. The Gamma Ray Spectrometer on the Lunar Prospector orbiter provided a global database of element abundances that resulted in a new understanding of the Moon’s crust. The Ion and Neutral Mass Spectrometer on Cassini has analyzed the chemical compositions of the atmosphere of Titan and active plumes on Enceladus. PMID:21402932

  8. Life support subsystem monitoring instrumentation

    NASA Technical Reports Server (NTRS)

    Powell, J. D.; Kostell, G. D.

    1974-01-01

    The recognition of the need for instrumentation in manned spacecraft life-support subsystems has increased significantly over the past several years. Of the required control and monitoring instrumentation, this paper will focus on the monitoring instrumentation as applied to life-support subsystems. The initial approach used independent sensors, independent sensor signal conditioning circuitry, and independent logic circuitry to provide shutdown protection only. This monitoring system was replaced with a coordinated series of printed circuit cards, each of which contains all the electronics to service one sensor and provide performance trend information, fault detection and isolation information, and shutdown protection. Finally, a review of sensor and instrumentation problems is presented, and the requirement for sensors with built-in signal conditioning and provisions for in situ calibration is discussed.

  9. Interfacing Microcomputers with Laboratory Instruments.

    ERIC Educational Resources Information Center

    Long, Joseph W.

    1983-01-01

    Describes development of microcomputer-controlled gamma scintillation spectrometer and chromatographic data analyzer, including design and construction of interface electronics and production of software. Includes diagrams of electric circuits and project evaluation indicating that both instruments functioned as intended. (JN)

  10. Course on Instruments Updates Teachers.

    ERIC Educational Resources Information Center

    Chemical and Engineering News, 1986

    1986-01-01

    Describes a course in chemical instrumentation for high school chemistry teachers, paid for by Union Carbide. Teachers used spectrophotometer, nuclear magnetic resonance spectrometer, atomic absorption spectrograph, gas chromatograph, liquid chromatograph and infrared spectrophotometer. Also describes other teacher education seminars. (JM)

  11. Spacecraft instrument technology and cosmochemistry.

    PubMed

    McSween, Harry Y; McNutt, Ralph L; Prettyman, Thomas H

    2011-11-29

    Measurements by instruments on spacecraft have significantly advanced cosmochemistry. Spacecraft missions impose serious limitations on instrument volume, mass, and power, so adaptation of laboratory instruments drives technology. We describe three examples of flight instruments that collected cosmochemical data. Element analyses by Alpha Particle X-ray Spectrometers on the Mars Exploration Rovers have revealed the nature of volcanic rocks and sedimentary deposits on Mars. The Gamma Ray Spectrometer on the Lunar Prospector orbiter provided a global database of element abundances that resulted in a new understanding of the Moon's crust. The Ion and Neutral Mass Spectrometer on Cassini has analyzed the chemical compositions of the atmosphere of Titan and active plumes on Enceladus. PMID:21402932

  12. Modular Approach to Instrumental Analysis.

    ERIC Educational Resources Information Center

    Deming, Richard L.; And Others

    1982-01-01

    To remedy certain deficiencies, an instrument analysis course was reorganized into six one-unit modules: optical spectroscopy, magnetic resonance, separations, electrochemistry, radiochemistry, and computers and interfacing. Selected aspects of the course are discussed. (SK)

  13. Trends in data acquisition instrumentation

    NASA Astrophysics Data System (ADS)

    Blanar, George J.

    1993-10-01

    Particle physics research demands unique data acquisition instrumentation in terms of speed, size, cost, and architecture. This paper will focus on principal issues related to trends in high-speed, large-scale, economical, sophisticated instrumentation for high energy physics, heavy ion, nuclear and atomic physics as well as large scale astronomical experiments. Examples will be taken from experiments at many national laboratories including BNL, FNAL, CERN, SLAC, etc., as well as LeCroy Corporation's 26 year history in the field of physics research instrumentation. Finally, instrumentation needs for the next generation of high energy, hadron colliders including the Superconducting Super Collider (SSC) and the Large Hadron Collider (LHC) at CERN will be reviewed and compared to current technologies.

  14. Aircraft Power-Plant Instruments

    NASA Technical Reports Server (NTRS)

    Sontag, Harcourt; Brombacher, W G

    1934-01-01

    This report supersedes NACA-TR-129 which is now obsolete. Aircraft power-plant instruments include tachometers, engine thermometers, pressure gages, fuel-quantity gages, fuel flow meters and indicators, and manifold pressure gages. The report includes a description of the commonly used types and some others, the underlying principle utilized in the design, and some design data. The inherent errors of the instrument, the methods of making laboratory tests, descriptions of the test apparatus, and data in considerable detail in the performance of commonly used instruments are presented. Standard instruments and, in cases where it appears to be of interest, those used as secondary standards are described. A bibliography of important articles is included.

  15. The MEPHISTO scientific space instrument

    NASA Astrophysics Data System (ADS)

    Cambon, G.; Cadet, G.; Favier, J. J.

    1987-02-01

    A furnace to study solidification on Earth and in orbit was developed. Design and performances in Bridgman-Stockbarger directional solidification are given in terms of thermal gradient achievables, thermal gradient stability, back-melting mastering, and quenching capabilities. In-situ measurements in real time of fundamental parameters for the solidification process control, associated with a possible interactivity between the principal investigator on ground and the instrument in orbit, are among the main features of the space instrument.

  16. Development and application of a simultaneous SPE-method for polycyclic aromatic hydrocarbons (PAHs), alkylated PAHs, heterocyclic PAHs (NSO-HET) and phenols in aqueous samples from German Rivers and the North Sea.

    PubMed

    Siemers, Anne-Kathrin; Mänz, Jan Sebastian; Palm, Wolf-Ulrich; Ruck, Wolfgang K L

    2015-03-01

    Polycyclic aromatic hydrocarbons (PAHs), heterocyclic PAHs (NSO-HETs), alkylated PAHs and phenols are known as the prevailing contaminants in groundwater at tar contaminated sites. Besides these local sources, the concentrations and the distribution in particular of NSO-HETs in environmental samples, such as rivers, have received notably less attention. To investigate their occurrence in river basins two sensitive analytical methods for the simultaneous extraction of 86 substances including NSO-HETs, classical EPA-PAHs, alkylated PAHs and phenols were developed: liquid-liquid extraction for the whole water phase and solid phase extraction for the dissolved water phase only. Solely GC-MS or additionally LC-MSMS for fractionated basic nitrogen heterocycles (N-HETs) were used for quantification. Limits of quantification were in the low ngL(-1) range. Concentrations were determined in 29 aqueous samples from 8 relatively large rivers located in Lower Saxony (Germany) and the North Sea. NSO-HETs had comparable or even higher sum concentrations than EPA-PAHs. N-HETs, especially acridine and quinolines with concentrations of up to 20ngL(-1) per substance, were predominant.

  17. 14 CFR 25.1337 - Powerplant instruments.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Powerplant instruments. 25.1337 Section 25... AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY AIRPLANES Equipment Instruments: Installation § 25.1337 Powerplant instruments. (a) Instruments and instrument lines. (1) Each powerplant and auxiliary power unit...

  18. INSTRUMENTATION FOR FAR INFRARED SPECTROSCOPY.

    SciTech Connect

    GRIFFITHS, P.R.; HOMES, C.

    2001-05-04

    Fourier transform spectrometers developed in three distinct spectral regions in the early 1960s. Pierre Connes and his coworkers in France developed remarkably sophisticated step-scan interferometers that permitted near-infrared spectra to be measured with a resolution of better than 0.0 1 cm{sup {minus}1}. These instruments may be considered the forerunners of the step-scan interferometers made by Bruker, Bio-Rad (Cambridge, MA, USA) and Nicolet although their principal application was in the field of astronomy. Low-resolution rapid-scanning interferometers were developed by Larry Mertz and his colleagues at Block Engineering (Cambridge, MA, USA) for remote sensing. Nonetheless, the FT-IR spectrometers that are so prevalent in chemical laboratories today are direct descendants of these instruments. The interferometers that were developed for far-infrared spectrometry in Gebbie's laboratory ,have had no commercial counterparts for at least 15 years. However, it could be argued that these instruments did as much to demonstrate the power of Fourier transform spectroscopy to the chemical community as any of the instruments developed for mid- and near-infrared spectrometry. Their performance was every bit as good as today's rapid-scanning interferometers. However, the market for these instruments is so small today that it has proved more lucrative to modify rapid-scanning interferometers that were originally designed for mid-infrared spectrometry than to compete with these instruments with slow continuous scan or step-scan interferometers.

  19. The SETI instrument development plan

    NASA Technical Reports Server (NTRS)

    Crow, R. B.

    1980-01-01

    The architecture of the instrument system for the SETI (Search for Extraterrestrial Intelligence) program is briefly described and the development approach used to implement the operational instruments is discussed. The two versions of the instrument system include a target survey instrument to observe at a very high sensitivity a selected set of interesting stars that have particular a priori promise, and a sky survey instrument to observe the entire celestial sphere at a lower sensitivity. The targeted survey utilizes the 305 meter antenna at Arecibo, Puerto Rico, a 64 meter DSN antenna, and other large radio telescopes. The Arecibo instrument provides the highest sensitivity by virtue of the antenna gain. The antenna line feeds cover an instantaneous frequency range of 50 MHz (tunable over 100 MHz), while the multichannel spectrum analyzer/signal detector is capable of analyzing a frequency segment 16 MHz wide with a maximum resolution of 1 Hz. The sky survey employs a listen-only, 34 meter antenna. The SETI breadboard development is also described.

  20. High Data Rate Instrument Study

    NASA Technical Reports Server (NTRS)

    Schober, Wayne; Lansing, Faiza; Wilson, Keith; Webb, Evan

    1999-01-01

    The High Data Rate Instrument Study was a joint effort between the Jet Propulsion Laboratory (JPL) and the Goddard Space Flight Center (GSFC). The objectives were to assess the characteristics of future high data rate Earth observing science instruments and then to assess the feasibility of developing data processing systems and communications systems required to meet those data rates. Instruments and technology were assessed for technology readiness dates of 2000, 2003, and 2006. The highest data rate instruments are hyperspectral and synthetic aperture radar instruments which are capable of generating 3.2 Gigabits per second (Gbps) and 1.3 Gbps, respectively, with a technology readiness date of 2003. These instruments would require storage of 16.2 Terebits (Tb) of information (RF communications case of two orbits of data) or 40.5 Tb of information (optical communications case of five orbits of data) with a technology readiness date of 2003. Onboard storage capability in 2003 is estimated at 4 Tb; therefore, all the data created cannot be stored without processing or compression. Of the 4 Tb of stored data, RF communications can only send about one third of the data to the ground, while optical communications is estimated at 6.4 Tb across all three technology readiness dates of 2000, 2003, and 2006 which were used in the study. The study includes analysis of the onboard processing and communications technologies at these three dates and potential systems to meet the high data rate requirements. In the 2003 case, 7.8% of the data can be stored and downlinked by RF communications while 10% of the data can be stored and downlinked with optical communications. The study conclusion is that only 1 to 10% of the data generated by high data rate instruments will be sent to the ground from now through 2006 unless revolutionary changes in spacecraft design and operations such as intelligent data extraction are developed.

  1. Analytical techniques and instrumentation: A compilation

    NASA Technical Reports Server (NTRS)

    1974-01-01

    Technical information on developments in instrumentation is arranged into four sections: (1) instrumentation for analysis; (2) analysis of matter; (3) analysis of electrical and mechanical phenomena; and (4) structural analysis. Patent information for two of the instruments described is presented.

  2. The instrument explosion--a study of aircraft cockpit instruments.

    PubMed

    Lovesey, E J

    1977-03-01

    Aircraft cockpit instruments have been increasing in number since the Wright Brothers made their first powered flight. As aeroplane development progresses, new systems are continually being added to improve performance or capability and cockpits have now reached the stage where there is often little space left in which to install the monitoring instruments for these additional systems. Fortunately, the advent of electronic cockpit displays offers a solution to this problem. One electronic display can be used to present the information previously requiring several conventional electro-mechanical instruments, with a consequent saving in cockpit panel space. However, cockpit displays must be matched to the pilot's information requirements and processing abilities. If this is not done the advantages of electronic displays will not be realised and the pilot will be in an even worse position than he was before.

  3. Identification and characterization of hetA, a gene that acts early in the process of morphological differentiation of heterocysts. [Anabaena

    SciTech Connect

    Holland, D.; Wolk, C.P. )

    1990-06-01

    Envelope polysaccharide is a major early diagnostic of differentiating heterocysts. The mutation in mutant EF116 of Anabaena sp. strain PCC 7120 reduces the cohesiveness of this polysaccharide. A 3.5-kilobase fragment of DNA cloned from the wild type of this Anabaena sp. was previously shown to complement this mutation. The authors present the nucleotide sequence of a 2,555-base-pair portion of this fragment containing an open reading frame (ORF) of 601 amino acids. Complementation analysis using deletion derives of the 3.5-kilobase fragment showed that the gene mutated in EF116, which they designate hetA, lies within this ORF. Transcription of hetA was induced as a result of deprivation for nitrate and yielded a monocistronic mRNA that was present at greatest abundance 7 h after nitrogen stepdown. At that time, proheterocysts could not be distinguished by light microscopy; transcription of nifHD, structural genes of nitrogenase, peaked much later. Situated 3{prime} to hetA are 4 identical repeats of the sequence 5{prime}-TTCAAAA-3{prime} and 12 repeats (10 identical) of the sequence 5{prime}-CCCCAAT-3{prime}. The 12 repeats, present within and near the 5{prime} end of a second ORF, are almost identical to repeats that have been reported to be present in the region between the petC and petA genes of a related cyanobacterium.

  4. On Representative Spaceflight Instrument and Associated Instrument Sensor Web Framework

    NASA Technical Reports Server (NTRS)

    Kizhner, Semion; Patel, Umeshkumar; Vootukuru, Meg

    2007-01-01

    Sensor Web-based adaptation and sharing of space flight mission resources, including those of the Space-Ground and Control-User communication segment, could greatly benefit from utilization of heritage Internet Protocols and devices applied for Spaceflight (SpaceIP). This had been successfully demonstrated by a few recent spaceflight experiments. However, while terrestrial applications of Internet protocols are well developed and understood (mostly due to billions of dollars in investments by the military and industry), the spaceflight application of Internet protocols is still in its infancy. Progress in the developments of SpaceIP-enabled instrument components will largely determine the SpaceIP utilization of those investments and acceptance in years to come. Likewise SpaceIP, the development of commercial real-time and instrument colocated computational resources, data compression and storage, can be enabled on-board a spacecraft and, in turn, support a powerful application to Sensor Web-based design of a spaceflight instrument. Sensor Web-enabled reconfiguration and adaptation of structures for hardware resources and information systems will commence application of Field Programmable Arrays (FPGA) and other aerospace programmable logic devices for what this technology was intended. These are a few obvious potential benefits of Sensor Web technologies for spaceflight applications. However, they are still waiting to be explored. This is because there is a need for a new approach to spaceflight instrumentation in order to make these mature sensor web technologies applicable for spaceflight. In this paper we present an approach in developing related and enabling spaceflight instrument-level technologies based on the new concept of a representative spaceflight Instrument Sensor Web (ISW).

  5. AMO Instrumentation for the LCLS

    NASA Astrophysics Data System (ADS)

    Bozek, John

    2008-05-01

    The Linac Coherent Light Source (LCLS) x-ray free electron laser (FEL) facility at the Stanford Linear Accelerator Center (SLAC) is quickly nearing completion. When finished in summer 2009, the LCLS will produce ultrafast pulses of x-rays with photon energies of 800 -- 8000 eV, intensities >= 10^13 ph/s and pulse durations of 150 fs, at a repetition rate of 120Hz. A suite of four instruments, including one dedicated to AMO science, are currently being designed for first experiments with the LCLS source. The design of the AMO instrument is in the final stages with construction to begin later this year. Included in the AMO instrumentation are optics to focus the LCLS beam to a waist of ˜2μm, an experimental chamber with a supersonic pulsed gas jet, a set of five time-of-flight electron energy spectrometers, one of three ion spectrometers, and two x-ray fluorescence spectrometers, and a synchronized laser for pump-probe experiments. A downstream diagnostics chamber with instruments to measure the relevant parameters of each FEL pulse is also included. Plans for first experiments along with designs of the instrumentation will be presented. Guidance for experimental proposals for the LCLS will also be provided for prospective users.

  6. Instrumental Capabilities of the EST

    NASA Astrophysics Data System (ADS)

    Collados Vera, M.; EST Team

    2012-12-01

    The EST has recently finished its conceptual design study. A number of instruments have been devised to make possible the observation of the solar photosphere and chromosphere with high spatial, spectral, and temporal resolution, as well as with high polarimetric sensitivity. To achieve these goals, the telescope is provided with a powerful MCAO system and a polarimetrically compensated optical design. In this paper, a summary of the present situation of the telescope and its different subsystems is outlined. Especial emphasis is put in the description of the instruments and of the flexible light distribution system. The latter will allow scientists to perform observations using all instruments at the same time or individually, to maximize the efficiency of the system. With this expected performance, EST will provide to the community with data of unprecedented quality to study solar magnetic phenomena at its finest scales.

  7. FTIR instrumentation for atmospheric observations

    NASA Astrophysics Data System (ADS)

    Knuteson, Robert O.; Revercomb, Henry E.; Best, Fred A.; Smith, William L.

    1993-09-01

    During the last six years, extensive observations of atmospheric emitted radiance in the spectral region from 3.6 - 20 micrometers with resolving powers of 1000 - 4000 have been made, both from the ground and nadir viewing from NASA high altitude aircraft. Two recent field experiments in which both instruments participated are the FIRE II/SPECTRE experiment Nov. - Dec. 1991 in Coffeyville, KS and the STORMFEST experiment Feb. - Mar. 1992 in Seneca, KS. Experience with these instruments has led to instrument designs for advanced sounders on geostationary and polar orbiting satellites. Applications include remote sensing of atmospheric temperature and water vapor for improved weather forecasting, measurement of cloud radiative impact for improvement of global climate modelling, and trace gas retrieval for climate and air pollution monitoring.

  8. An improved instrument mounting arm.

    PubMed

    Gendeh, B S; Khalid, B A; Alberti, P W

    2001-02-01

    Although some form of commercial instrument mounting arm is available, a paucity of information in the literature may cause problems in selecting the most appropriate model for an ENT department wishing to trial their invention for use in the clinic or operating theatre. The instrument mounting arm described here is based on existing designs used by hobbyists and model makers for many years but the main benefit of this innovation is its multi-purpose use in the operating theatre and cost effectiveness since it is made of aluminum alloy. It is compact, stable and easily adjustable and can incorporate an endoscope holder or an operating end piece to mount various ENT instruments that offers considerable advantages to the unassisted operator.

  9. Advanced Light Source instrumentation overview

    SciTech Connect

    Kim, C.H.; Hinkson, J.

    1992-10-01

    The accelerator instrumentation played a vital role in commissioning the ALS injector accelerator. It helped us to see whether electron dynamics agreed with our theoretical predictions and important beam parameters met the design specifications. It helped us to see where beam losses occurred and why. In this paper we will start with a brief description of the ALS accelerator complex and the expected performance of it. Then we will describe each diagnostics instrument by its construction, operational principle, requirements, and our experiences with it. We will describe the wall current monitor, the scintillator, the Faraday cup, the beam collimator, the beam position monitor, the direct-current current transformer (DCCT), the traveling wave electrodes the Sabersky finger, and other special instruments. Finally, we will go into some detail on how we measured the beam emittances, the closed orbit, and the betatron tunes.

  10. [Portable instrument for arteriosclerosis assessment].

    PubMed

    Cao, Shuai; Chen, Xiang

    2014-01-01

    A portable instrument for arteriosclerosis assessment containing sensor module, acquisition board and embedded module was developed for home care in this paper. The sensor module consists of one ECG module and three pulse wave extraction modules, synchronously acquiring human ECG and pulse wave signal of carotid, radial, and dorsal, respectively. The acquisition board converts the sensor module's analog output signals into digital signals and transmits them to the embedded module. The embedded module realizes the functions including signal display, storage and the calculation and output of pulse wave velocity. The structure of the proposed portable instrument is simple, easy to use, and easy to expand. Small size, low cost, and low power consumption are also the advantages of this device. Experimental results demonstrated that the proposed portable instrument for arteriosclerosis assessment has high accuracy, good repeatability and can assess the degree of atherosclerosis appropriately.

  11. Multifunction Imaging and Spectroscopic Instrument

    NASA Technical Reports Server (NTRS)

    Mouroulis, Pantazis

    2004-01-01

    A proposed optoelectronic instrument would perform several different spectroscopic and imaging functions that, heretofore, have been performed by separate instruments. The functions would be reflectance, fluorescence, and Raman spectroscopies; variable-color confocal imaging at two different resolutions; and wide-field color imaging. The instrument was conceived for use in examination of minerals on remote planets. It could also be used on Earth to characterize material specimens. The conceptual design of the instrument emphasizes compactness and economy, to be achieved largely through sharing of components among subsystems that perform different imaging and spectrometric functions. The input optics for the various functions would be mounted in a single optical head. With the exception of a targeting lens, the input optics would all be aimed at the same spot on a specimen, thereby both (1) eliminating the need to reposition the specimen to perform different imaging and/or spectroscopic observations and (2) ensuring that data from such observations can be correlated with respect to known positions on the specimen. The figure schematically depicts the principal components and subsystems of the instrument. The targeting lens would collect light into a multimode optical fiber, which would guide the light through a fiber-selection switch to a reflection/ fluorescence spectrometer. The switch would have four positions, enabling selection of spectrometer input from the targeting lens, from either of one or two multimode optical fibers coming from a reflectance/fluorescence- microspectrometer optical head, or from a dark calibration position (no fiber). The switch would be the only moving part within the instrument.

  12. Neutron-multiplication measurement instrument

    SciTech Connect

    Nixon, K.V.; Dowdy, E.J.; France, S.W.; Millegan, D.R.; Robba, A.A.

    1982-01-01

    The Advanced Nuclear Technology Group of the Los Alamos National Laboratory is now using intelligent data-acquisition and analysis instrumentation for determining the multiplication of nuclear material. Earlier instrumentation, such as the large NIM-crate systems, depended on house power and required additional computation to determine multiplication or to estimate error. The portable, battery-powered multiplication measurement unit, with advanced computational power, acquires data, calculates multiplication, and completes error analysis automatically. Thus, the multiplication is determined easily and an available error estimate enables the user to judge the significance of results.

  13. Formation Flying and Deformable Instruments

    SciTech Connect

    Rio, Yvon

    2009-05-11

    Astronomers have always attempted to build very stable instruments. They fight all that can cause mechanical deformation or image motion. This has led to well established technologies (autoguide, active optics, thermal control, tip/tilt correction), as well as observing methods based on the use of controlled motion (scanning, micro scanning, shift and add, chopping and nodding). Formation flying disturbs this practice. It is neither possible to reduce the relative motion to very small amplitudes, nor to control it at will. Some impacts on Simbol-X instrument design, and operation are presented.

  14. Formation Flying and Deformable Instruments

    NASA Astrophysics Data System (ADS)

    Rio, Yvon

    2009-05-01

    Astronomers have always attempted to build very stable instruments. They fight all that can cause mechanical deformation or image motion. This has led to well established technologies (autoguide, active optics, thermal control, tip/tilt correction), as well as observing methods based on the use of controlled motion (scanning, micro scanning, shift and add, chopping and nodding). Formation flying disturbs this practice. It is neither possible to reduce the relative motion to very small amplitudes, nor to control it at will. Some impacts on Simbol-X instrument design, and operation are presented.

  15. Sample acquisition and instrument deployment

    NASA Technical Reports Server (NTRS)

    Boyd, Robert C.

    1995-01-01

    Progress is reported in developing the Sample Acquisition and Instrument Deployment (SAID) system, a robotic system for deploying science instruments and acquiring samples for analysis. The system is a conventional four degree of freedom manipulator 2 meters in length. A baseline design has been achieved through analysis and trade studies. The design considers environmental operating conditions on the surface of Mars, as well as volume constraints on proposed Mars landers. Control issues have also been studied, and simulations of joint and tip movements have been performed. The systems have been fabricated and tested in environmental chambers, as well as soil testing and robotic control testing.

  16. Instrumentation in Diffuse Optical Imaging

    PubMed Central

    Zhang, Xiaofeng

    2014-01-01

    Diffuse optical imaging is highly versatile and has a very broad range of applications in biology and medicine. It covers diffuse optical tomography, fluorescence diffuse optical tomography, bioluminescence, and a number of other new imaging methods. These methods of diffuse optical imaging have diversified instrument configurations but share the same core physical principle – light propagation in highly diffusive media, i.e., the biological tissue. In this review, the author summarizes the latest development in instrumentation and methodology available to diffuse optical imaging in terms of system architecture, light source, photo-detection, spectral separation, signal modulation, and lastly imaging contrast. PMID:24860804

  17. Air Quality Instrumentation. Volume 2.

    ERIC Educational Resources Information Center

    Scales, John W., Ed.

    To insure a wide dissemination of information describing advances in measurement and control techniques, the Instrument Society of America (ISA) has published this monograph of selected papers, the second in a series, from recent ISA symposia dealing with air pollution. Papers range from a discussion of individual pollutant measurements to…

  18. Instrumentation System Diagnoses a Thermocouple

    NASA Technical Reports Server (NTRS)

    Perotti, Jose; Santiago, Josephine; Mata, Carlos; Vokrot, Peter; Zavala, Carlos; Burns, Bradley

    2008-01-01

    An improved self-validating thermocouple (SVT) instrumentation system not only acquires readings from a thermocouple but is also capable of detecting deterioration and a variety of discrete faults in the thermocouple and its lead wires. Prime examples of detectable discrete faults and deterioration include open- and short-circuit conditions and debonding of the thermocouple junction from the object, the temperature of which one seeks to measure. Debonding is the most common cause of errors in thermocouple measurements, but most prior SVT instrumentation systems have not been capable of detecting debonding. The improved SVT instrumentation system includes power circuitry, a cold-junction compensator, signal-conditioning circuitry, pulse-width-modulation (PWM) thermocouple-excitation circuitry, an analog-to-digital converter (ADC), a digital data processor, and a universal serial bus (USB) interface. The system can operate in any of the following three modes: temperature measurement, thermocouple validation, and bonding/debonding detection. The software running in the processor includes components that implement statistical algorithms to evaluate the state of the thermocouple and the instrumentation system. When the power is first turned on, the user can elect to start a diagnosis/ monitoring sequence, in which the PWM is used to estimate the characteristic times corresponding to the correct configuration. The user also has the option of using previous diagnostic values, which are stored in an electrically erasable, programmable read-only memory so that they are available every time the power is turned on.

  19. Vacuum enhanced cutaneous biopsy instrument

    DOEpatents

    Collins, Joseph

    2000-01-01

    A syringe-like disposable cutaneous biopsy instrument equipped with a tubular blade at its lower end, and designed so that a vacuum is created during use, said vacuum serving to retain undeformed a plug of tissue cut from a patient's skin.

  20. Geoscience experiments in boreholes: instrumentation

    SciTech Connect

    Traeger, R.K.

    1984-05-01

    Drilling is the only method available to obtain unambiguous information on processes occurring in the earth's crust. When core and virgin formation fluid samples are available, the geological state of the formation may be defined in the vicinity of the borehole with little ambiguity. Unfortunately, core recovery is expensive and often not complete, and drilling muds contaminate formation fluids. Thus, investigations turn to downhole instrumentation systems to evaluate in situ formation parameters. Some such instruments and the associated interpretative techniques are well developed, especially if they find usage in the evaluation of hydrocarbon reservoirs. Other sytems, particularly those that yield geochemical information are, at best, shallow-hole devices, but they could be engineered for deep-hole applications. Interpretations of logs obtained in igneous and metamorphic systems are not well developed. Finally, measurements away from the immediate vicinity of the borehole are possible but the technology is primitive. In situ instrumentation capabilities and needs for research in boreholes will be reviewed; the review will include details from recent US and European discussions of instrumentation needs. The capability and availability of slim hole logging tools will be summarized. Temperature limitations of the overall logging system will be discussed (current limits are 300/sup 0/C) and options for measurements to 500/sup 0/C will be described.

  1. Air Quality Instrumentation. Volume 1.

    ERIC Educational Resources Information Center

    Scales, John W., Ed.

    To insure a wide dissemination of information describing advances in measurement and control techniques, the Instrument Society of America (ISA) has published this monograph of selected papers from recent ISA symposia dealing with air pollution. Papers range from a discussion of some relatively new applications of proven techniques to discussions…

  2. An Instrument to Measure Anomia.

    ERIC Educational Resources Information Center

    Moore, Allen B.

    1980-01-01

    Four hundred and eighty-six disadvantaged adults from North Carolina were the subjects in a study that factor-analyzed three instruments designed to measure anomia, yielding a 12-item unidimensional scale. (The refined combination scale is presented as of potential usefulness for research on the effects of educational intervention on anomia.) (LRA)

  3. Instrument sterilization in orthodontic offices.

    PubMed

    Matlack, R E

    1979-07-01

    1. Three different quaternary ammonium compound solutions remained bactericidal against specific vegetative bacteria in three orthodontic offices over a ten day working period. However, no spore formers or viruses were tested. 2. Bacterial contaminants were cultured on pliers and scalers at the chair at least once in each of three orthodontic offices sampled twice a day for ten working days. 3. Sampled chairside instruments wiped with an alcohol sponge only, between patients, were contaminated an excessive 32.5% of the time, too frequently to be seriously considered for routine disinfection of pliers. 4. Chairside instruments, sampled regardless of other means of disinfection or sterilization used, were contaminated from 3.5 to 15% of the time. Therefore, storage and handling of orthodontic instruments must be evaluated and upgraded to prevent recontamination of previously sterilized instruments. 5. Staff personnel need courses in sterilization and disinfection procedures to prevent cross contamination from patient to patient and to protect themselves. These courses should be related specifically to orthodontic practice procedures.

  4. Instrumental Surveillance of Water Quality.

    ERIC Educational Resources Information Center

    Miller, J. A.; And Others

    The role analytical instrumentation performs in the surveillance and control of the quality of water resources is reviewed. Commonly performed analyses may range from simple tests for physical parameters to more highly sophisticated radiological or spectrophotometric methods. This publication explores many of these types of water quality analyses…

  5. Literature Review of Multicultural Instrumentation

    ERIC Educational Resources Information Center

    Sarraj, Huda; Carter, Stacy; Burley, Hansel

    2015-01-01

    Demographic changes at the national level emphasize a critical need for multicultural education to be included as part of undergraduate education. This critical review of the literature examines 10 multicultural instruments that are suitable for use in K-12 or higher education institutions. This is a novel literature review in that it is the first…

  6. Experimenting with Brass Musical Instruments.

    ERIC Educational Resources Information Center

    LoPresto, Michael C.

    2003-01-01

    Describes experiments to address the properties of brass musical instruments that can be used to demonstrate sound in any level physics course. The experiments demonstrate in a quantitative fashion the effects of the mouthpiece and bell on the frequencies of sound waves and thus the musical pitches produced. (Author/NB)

  7. Remote Instrumentation for Teaching Laboratory

    ERIC Educational Resources Information Center

    Baran, Jit; Currie, Ron; Kennepohl, Dietmar

    2004-01-01

    The feasibility of using current software, such as PC-Duo, PCAnywhere or LabVIEW, in training students in instrumental analysis from a remote location is investigated. Findings show that creation of online features is crucial to the use and learning by students and the development of a suitable Web site, which provides an easy-to-use interface to…

  8. Vacuum Enhanced Cutaneous Biopsy Instrument

    SciTech Connect

    Collins, Joseph

    1999-06-25

    A syringe-like disposable cutaneous biopsy instrument equipped with a tubular blade at its lower end, and designed so that a vacuum is created during use, said vacuum serving to retain undeformed a plug of tissue cut from a patient's skin.

  9. Psychology Needs Realism, Not Instrumentalism

    ERIC Educational Resources Information Center

    Haig, Brian D.

    2005-01-01

    In this article, the author presents his comments on "Realism, Instrumentalism, and Scientific Symbiosis: Psychological Theory as a Search for Truth and the Discovery of Solutions" by John T. Cacioppo, Gun R. Semin and Gary G. Berntson. In the original article, the authors recommended the combined use of the philosophies of scientific realism and…

  10. Mobile Instruments Measure Atmospheric Pollutants

    NASA Technical Reports Server (NTRS)

    2009-01-01

    As a part of NASA's active research of the Earth s atmosphere, which has included missions such as the Atmospheric Laboratory of Applications and Science (ATLAS, launched in 1992) and the Total Ozone Mapping Spectrometer (TOMS, launched on the Earth Probe satellite in 1996), the Agency also performs ground-based air pollution research. The ability to measure trace amounts of airborne pollutants precisely and quickly is important for determining natural patterns and human effects on global warming and air pollution, but until recent advances in field-grade spectroscopic instrumentation, this rapid, accurate data collection was limited and extremely difficult. In order to understand causes of climate change and airborne pollution, NASA has supported the development of compact, low power, rapid response instruments operating in the mid-infrared "molecular fingerprint" portion of the electromagnetic spectrum. These instruments, which measure atmospheric trace gases and airborne particles, can be deployed in mobile laboratories - customized ground vehicles, typically - to map distributions of pollutants in real time. The instruments must be rugged enough to operate rapidly and accurately, despite frequent jostling that can misalign, damage, or disconnect sensitive components. By measuring quickly while moving through an environment, a mobile laboratory can correlate data and geographic points, revealing patterns in the environment s pollutants. Rapid pollutant measurements also enable direct determination of pollutant sources and sinks (mechanisms that remove greenhouse gases and pollutants), providing information critical to understanding and managing atmospheric greenhouse gas and air pollutant concentrations.

  11. Instrument Reporting Practices in Second Language Research

    ERIC Educational Resources Information Center

    Derrick, Deirdre J.

    2016-01-01

    Second language (L2) researchers often have to develop or change the instruments they use to measure numerous constructs (Norris & Ortega, 2012). Given the prevalence of researcher-developed and -adapted data collection instruments, and given the profound effect instrumentation can have on results, thorough reporting of instrumentation is…

  12. Concert Band Instrumentation: Realities and Remedies.

    ERIC Educational Resources Information Center

    Rogers, George L.

    1991-01-01

    Suggests ways to solve problems resulting from imbalanced instrumentation in school concert bands. Identifies sources of imbalance. Encourages band directors to plan for correct instrumentation, to match students' characteristics and abilities to instruments, and to recruit students to play needed instruments. Discusses the benefits of balanced…

  13. 14 CFR 23.1381 - Instrument lights.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Instrument lights. 23.1381 Section 23.1381... STANDARDS: NORMAL, UTILITY, ACROBATIC, AND COMMUTER CATEGORY AIRPLANES Equipment Lights § 23.1381 Instrument lights. The instrument lights must— (a) Make each instrument and control easily readable and...

  14. 14 CFR 25.1381 - Instrument lights.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Instrument lights. 25.1381 Section 25.1381... STANDARDS: TRANSPORT CATEGORY AIRPLANES Equipment Lights § 25.1381 Instrument lights. (a) The instrument lights must— (1) Provide sufficient illumination to make each instrument, switch and other...

  15. 14 CFR 23.1381 - Instrument lights.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Instrument lights. 23.1381 Section 23.1381... STANDARDS: NORMAL, UTILITY, ACROBATIC, AND COMMUTER CATEGORY AIRPLANES Equipment Lights § 23.1381 Instrument lights. The instrument lights must— (a) Make each instrument and control easily readable and...

  16. 14 CFR 25.1381 - Instrument lights.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Instrument lights. 25.1381 Section 25.1381... STANDARDS: TRANSPORT CATEGORY AIRPLANES Equipment Lights § 25.1381 Instrument lights. (a) The instrument lights must— (1) Provide sufficient illumination to make each instrument, switch and other...

  17. 14 CFR 121.307 - Engine instruments.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Engine instruments. 121.307 Section 121.307..., FLAG, AND SUPPLEMENTAL OPERATIONS Instrument and Equipment Requirements § 121.307 Engine instruments. Unless the Administrator allows or requires different instrumentation for turbine engine...

  18. 14 CFR 121.307 - Engine instruments.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Engine instruments. 121.307 Section 121.307..., FLAG, AND SUPPLEMENTAL OPERATIONS Instrument and Equipment Requirements § 121.307 Engine instruments. Unless the Administrator allows or requires different instrumentation for turbine engine...

  19. 14 CFR 23.1381 - Instrument lights.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Instrument lights. 23.1381 Section 23.1381... STANDARDS: NORMAL, UTILITY, ACROBATIC, AND COMMUTER CATEGORY AIRPLANES Equipment Lights § 23.1381 Instrument lights. The instrument lights must— (a) Make each instrument and control easily readable and...

  20. 14 CFR 23.1381 - Instrument lights.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Instrument lights. 23.1381 Section 23.1381... STANDARDS: NORMAL, UTILITY, ACROBATIC, AND COMMUTER CATEGORY AIRPLANES Equipment Lights § 23.1381 Instrument lights. The instrument lights must— (a) Make each instrument and control easily readable and...

  1. 14 CFR 23.1381 - Instrument lights.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Instrument lights. 23.1381 Section 23.1381... STANDARDS: NORMAL, UTILITY, ACROBATIC, AND COMMUTER CATEGORY AIRPLANES Equipment Lights § 23.1381 Instrument lights. The instrument lights must— (a) Make each instrument and control easily readable and...

  2. 14 CFR 25.1381 - Instrument lights.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Instrument lights. 25.1381 Section 25.1381... STANDARDS: TRANSPORT CATEGORY AIRPLANES Equipment Lights § 25.1381 Instrument lights. (a) The instrument lights must— (1) Provide sufficient illumination to make each instrument, switch and other...

  3. 14 CFR 25.1381 - Instrument lights.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Instrument lights. 25.1381 Section 25.1381... STANDARDS: TRANSPORT CATEGORY AIRPLANES Equipment Lights § 25.1381 Instrument lights. (a) The instrument lights must— (1) Provide sufficient illumination to make each instrument, switch and other...

  4. 14 CFR 25.1381 - Instrument lights.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Instrument lights. 25.1381 Section 25.1381... STANDARDS: TRANSPORT CATEGORY AIRPLANES Equipment Lights § 25.1381 Instrument lights. (a) The instrument lights must— (1) Provide sufficient illumination to make each instrument, switch and other...

  5. 14 CFR 25.1333 - Instrument systems.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Instrument systems. 25.1333 Section 25.1333... STANDARDS: TRANSPORT CATEGORY AIRPLANES Equipment Instruments: Installation § 25.1333 Instrument systems. For systems that operate the instruments required by § 25.1303(b) which are located at each...

  6. 14 CFR 29.1333 - Instrument systems.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Instrument systems. 29.1333 Section 29.1333... STANDARDS: TRANSPORT CATEGORY ROTORCRAFT Equipment Instruments: Installation § 29.1333 Instrument systems. For systems that operate the required flight instruments which are located at each pilot's...

  7. 32 CFR 21.665 - Nonprocurement instrument.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Nonprocurement instrument. 21.665 Section 21.665... REGULATIONS DoD GRANTS AND AGREEMENTS-GENERAL MATTERS Definitions § 21.665 Nonprocurement instrument. A legal instrument other than a procurement contract. Examples include instruments of financial assistance, such...

  8. 21 CFR 882.4525 - Microsurgical instrument.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Microsurgical instrument. 882.4525 Section 882...) MEDICAL DEVICES NEUROLOGICAL DEVICES Neurological Surgical Devices § 882.4525 Microsurgical instrument. (a) Identification. A microsurgical instrument is a nonpowered surgical instrument used in neurological...

  9. Instrumentation requirements for the ESF thermomechanical experiments

    SciTech Connect

    Pott, J.; Brechtel, C.E.

    1992-12-31

    In situ thermomechanical experiments are planned as part of the Yucca Mountain Site Characterization Project that require instruments to measure stress and displacement at temperatures that exceed the typical specifications of existing geotechnical instruments. A high degree of instrument reliability will also be required to satisfy the objectives of the experiments, therefore a study was undertaken to identify areas where improvement in instrument performance was required. A preliminary list of instruments required for the experiments was developed, based on existing test planning and analysis. Projected temperature requirements were compared to specifications of existing instruments to identify instrumentation development needs. Different instrument technologies, not currently employed in geotechnical instrumentation, were reviewed to identify potential improvements of existing designs for the high temperature environment. Technologies with strong potentials to improve instrument performance with relatively high reliability include graphite fiber composite materials, fiber optics, and video imagery.

  10. ACRF Instrumentation Status and Information - June 2009

    SciTech Connect

    JW Voyles

    2009-06-01

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Climate Research Facility instrumentation status. The report is divided into the following five sections: (1) new instrumentation in the process of being acquired and deployed, (2) field campaigns, (3) existing instrumentation and progress on improvements or upgrades, (4) proposed future instrumentation, and (5) Small Business Innovation Research instrument development.

  11. ACRF Instrumentation Status and Information August 2009

    SciTech Connect

    JW Voyles

    2009-09-09

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Climate Research Facility instrumentation status. The report is divided into the following five sections: (1) new instrumentation in the process of being acquired and deployed, (2) field campaigns, (3) existing instrumentation and progress on improvements or upgrades, (4) proposed future instrumentation, and (5) Small Business Innovation Research instrument development.

  12. ACRF Instrumentation Status and Information April 2009

    SciTech Connect

    Voyles, JW

    2009-05-07

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Climate Research Facility instrumentation status. The report is divided into the following five sections: (1) new instrumentation in the process of being acquired and deployed, (2) field campaigns, (3) existing instrumentation and progress on improvements or upgrades, (4) proposed future instrumentation, and (5) Small Business Innovation Research instrument development.

  13. ACRF Instrumentation Status and Information September 2009

    SciTech Connect

    JW Voyles

    2009-10-01

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Climate Research Facility instrumentation status. The report is divided into the following five sections: (1) new instrumentation in the process of being acquired and deployed, (2) field campaigns, (3) existing instrumentation and progress on improvements or upgrades, (4) proposed future instrumentation, and (5) Small Business Innovation Research instrument development.

  14. ACRF Instrumentation Status and Information July 2009

    SciTech Connect

    JW Voyles

    2009-08-13

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Climate Research Facility instrumentation status. The report is divided into the following five sections: (1) new instrumentation in the process of being acquired and deployed, (2) field campaigns, (3) existing instrumentation and progress on improvements or upgrades, (4) proposed future instrumentation, and (5) Small Business Innovation Research instrument development.

  15. ACRF Instrumentation Status and Information May 2009

    SciTech Connect

    JW Voyles

    2009-05-01

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Climate Research Facility instrumentation status. The report is divided into the following five sections: (1) new instrumentation in the process of being acquired and deployed, (2) field campaigns, (3) existing instrumentation and progress on improvements or upgrades, (4) proposed future instrumentation, and (5) Small Business Innovation Research instrument development.

  16. Epithermal neutron instrumentation at ISIS

    NASA Astrophysics Data System (ADS)

    Gorini, G.; Festa, G.; Andreani, C.

    2014-12-01

    The advent of pulsed neutron sources makes available high epithermal neutron fluxes (in the energy range between 500 meV and 100 eV). New dedicated instrumentation, such as Resonance Detectors, was developed at ISIS spallation neutron source in the last years to apply the specific properties of this kind of neutron beam to the study of condensed matter. New detection strategies like Filter Difference method and Foil Cycling Technique were also developed in parallel to the detector improvement at the VESUVIO beamline. Recently, epithermal neutron beams were also used at the INES beamline to study elemental and isotopic composition of materials, with special application to cultural heritage studies. In this paper we review a series of epithermal neutron instrumentation developed at ISIS, their evolution over time and main results obtained.

  17. Dual physiological rate measurement instrument

    NASA Technical Reports Server (NTRS)

    Cooper, Tommy G. (Inventor)

    1990-01-01

    The object of the invention is to provide an instrument for converting a physiological pulse rate into a corresponding linear output voltage. The instrument which accurately measures the rate of an unknown rectangular pulse wave over an extended range of values comprises a phase-locked loop including a phase comparator, a filtering network, and a voltage-controlled oscillator, arranged in cascade. The phase comparator has a first input responsive to the pulse wave and a second input responsive to the output signal of the voltage-controlled oscillator. The comparator provides a signal dependent on the difference in phase and frequency between the signals appearing on the first and second inputs. A high-input impedance amplifier accepts an output from the filtering network and provides an amplified output DC signal to a utilization device for providing a measurement of the rate of the pulse wave.

  18. Instrument safety in explosive atmospheres.

    PubMed

    Bossert, J A

    1975-01-01

    The current "Energy Crisis" has dramatically increased our potential need for coal, the worlds most abundant fossil fuel. This will probably lead to a greater use of automation and instrumentation in the coal mining industry. The presence of methane in coal mines and in the coal itself plus the presence of coal dust, both of which can form an explosive atmosphere in air, means that the possibility of a gas or coal dust ignition must be considered when designing, purchasing and installing new equipment in this industry. In addition, many metallurgical processes involve the use of potentially explosive substances against which similar safety precautions must be taken. This paper outlines the various methods of protection currently in use and proposed for electrical instruments in explosive atmospheres, with particular emphasis on the work of the International Electrotechnical Commission.

  19. Recent developments in hydrologic instrumentation

    USGS Publications Warehouse

    Latkovich, Vito J.; Futrell, James C.; Kane, Douglas L.

    1986-01-01

    The programs of the U.S. Geological Survey require instrumentation for collecting and monitoring hydrologic data in cold regions. The availability of space-age materials and implementation of modern electronics and mechanics is making possible the recent developments of hydrologic instrumentation, especially in the area of measuring streamflow under ice cover. Material developments include: synthetic-fiber sounding and tag lines; polymer (plastic) sheaves, pulleys, and sampler components; and polymer (plastic) current-meter bucket wheels. Electronic and mechanical developments include: a current-meter digitizer; a fiber-optic closure system for current-meters; non-contact water-level sensors; an adaptable hydrologic data acquisition system; a minimum data recorder; an ice rod; an ice foot; a handled sediment sampler; a light weight ice auger with improved cutter head and blades; and an ice chisel.

  20. Venezuelan plant completes instrument upgrade

    SciTech Connect

    Martinez, H.; Garcia, C.O.

    1996-07-22

    The Lamarliquido LPG plant, offshore Lake Maracaibo, Venezuela, has received a major upgrade to its control system after 25 years of pneumatic instrumentation. The plant is now operating fully remote from a new central control room with a maximum production of 5,500 b/d, expected to go to 6,600 b/d. The phases of the project included installation and integration of four control systems: distributed control system; fire prevention, detection, and control system; refrigeration process turbocompressor control system; and emergency shutdown system. The paper describes the 1960s vintage instrumentation, the modernization objectives and phases, the distributed control system, the fire control system, gas and fire detection, the turbocompressor system, emergency shutdown system, and plant shutdown logic.

  1. The USNA MIDN Microdosimeter Instrument

    NASA Technical Reports Server (NTRS)

    Pisacane, V. L.; Ziegler, J. F.; Nelson, M. E.; Dolecek, Q.; Heyne, J.; Veade, T.; Rosenfeld, A. B.; Cucinotta, F. A.; Zaider, M.; Dicello, J. F.

    2006-01-01

    This paper describes the MIcroDosimetry iNstrument (MIDN) mission now under development at the United States Naval Academy. The instrument is manifested to fly on the MidSTAR-1 spacecraft, which is the second spacecraft to be developed and launched by the Academy s faculty and midshipmen. Launch is scheduled for 1 September 2006 on an ATLAS-5 launch vehicle. MIDN is a rugged, portable, low power, low mass, solid-state microdosimeter designed to measure in real time the energy distributions of energy deposited by radiation in microscopic volumes. The MIDN microdosimeter sensor is a reverse-biased silicon p-n junction array in a Silicon-On-Insulator (SOI) configuration. Microdosimetric frequency distributions as a function of lineal energies determine the radiation quality factors in support of radiation risk estimation to humans.

  2. In Situ Instruments: Overview of In Situ Instruments for Deployment in Extreme Environments

    NASA Technical Reports Server (NTRS)

    Taylor, M.; Cardell, G.

    2000-01-01

    This presentation reviews the design and specifications for several instruments for deployment in extreme environments. The instruments are: (1) In Situ Geochronology Instrument, (2) Laser Ablation Sampling Instrument, (3) Micro Hygrometer (4) Micro Lidar, (5) Atmospheric Electron X-Ray Spectrometer and (6) Nuclear Magnetic Resonance Spectrometer. Included in the descriptions are the contact people and the objective of each instrument.

  3. High resolution tomographic instrument development

    SciTech Connect

    Not Available

    1992-08-01

    Our recent work has concentrated on the development of high-resolution PET instrumentation reflecting in part the growing importance of PET in nuclear medicine imaging. We have developed a number of positron imaging instruments and have the distinction that every instrument has been placed in operation and has had an extensive history of application for basic research and clinical study. The present program is a logical continuation of these earlier successes. PCR-I, a single ring positron tomograph was the first demonstration of analog coding using BGO. It employed 4 mm detectors and is currently being used for a wide range of biological studies. These are of immense importance in guiding the direction for future instruments. In particular, PCR-II, a volume sensitive positron tomograph with 3 mm spatial resolution has benefited greatly from the studies using PCR-I. PCR-II is currently in the final stages of assembly and testing and will shortly be placed in operation for imaging phantoms, animals and ultimately humans. Perhaps the most important finding resulting from our previous study is that resolution and sensitivity must be carefully balanced to achieve a practical high resolution system. PCR-II has been designed to have the detection characteristics required to achieve 3 mm resolution in human brain under practical imaging situations. The development of algorithms by the group headed by Dr. Chesler is based on a long history of prior study including his joint work with Drs. Pelc and Reiderer and Stearns. This body of expertise will be applied to the processing of data from PCR-II when it becomes operational.

  4. High resolution tomographic instrument development

    SciTech Connect

    Not Available

    1992-01-01

    Our recent work has concentrated on the development of high-resolution PET instrumentation reflecting in part the growing importance of PET in nuclear medicine imaging. We have developed a number of positron imaging instruments and have the distinction that every instrument has been placed in operation and has had an extensive history of application for basic research and clinical study. The present program is a logical continuation of these earlier successes. PCR-I, a single ring positron tomograph was the first demonstration of analog coding using BGO. It employed 4 mm detectors and is currently being used for a wide range of biological studies. These are of immense importance in guiding the direction for future instruments. In particular, PCR-II, a volume sensitive positron tomograph with 3 mm spatial resolution has benefited greatly from the studies using PCR-I. PCR-II is currently in the final stages of assembly and testing and will shortly be placed in operation for imaging phantoms, animals and ultimately humans. Perhaps the most important finding resulting from our previous study is that resolution and sensitivity must be carefully balanced to achieve a practical high resolution system. PCR-II has been designed to have the detection characteristics required to achieve 3 mm resolution in human brain under practical imaging situations. The development of algorithms by the group headed by Dr. Chesler is based on a long history of prior study including his joint work with Drs. Pelc and Reiderer and Stearns. This body of expertise will be applied to the processing of data from PCR-II when it becomes operational.

  5. High resolution tomographic instrument development

    NASA Astrophysics Data System (ADS)

    Our recent work has concentrated on the development of high-resolution PET instrumentation reflecting in part the growing importance of PET in nuclear medicine imaging. We have developed a number of positron imaging instruments and have the distinction that every instrument has been placed in operation and has had an extensive history of application for basic research and clinical study. The present program is a logical continuation of these earlier successes. PCR-I, a single ring positron tomograph was the first demonstration of analog coding using BGO. It employed 4 mm detectors and is currently being used for a wide range of biological studies. These are of immense importance in guiding the direction for future instruments. In particular, PCR-II, a volume sensitive positron tomograph with 3 mm spatial resolution has benefitted greatly from the studies using PCR-I. PCR-II is currently in the final stages of assembly and testing and will shortly be placed in operation for imaging phantoms, animals and ultimately humans. Perhaps the most important finding resulting from our previous study is that resolution and sensitivity must be carefully balanced to achieve a practical high resolution system. PCR-II has been designed to have the detection characteristics required to achieve 3 mm resolution in human brain under practical imaging situations. The development of algorithms by the group headed by Dr. Chesler is based on a long history of prior study including his joint work with Drs. Pelc and Reiderer and Stearns. This body of expertise will be applied to the processing of data from PCR-II when it becomes operational.

  6. NCSU PULSTAR Reactor instrumentation upgrade

    SciTech Connect

    Perez, P.B.; Bilyj, S.J.

    1993-08-12

    The Nuclear Reactor Program at North Carolina State University initiated an upgrade program at the NCSU PULSTAR Reactor in 1990. Twenty-year-old instrumentation is currently undergoing replacement with solid-state and current technology equipment. The financial assistance from the United States Department of Energy has been the primary source of support. This interim report provides the status of the first two phases of the upgrade program.

  7. SMAP Instrument Mechanical System Engineering

    NASA Technical Reports Server (NTRS)

    Slimko, Eric; French, Richard; Riggs, Benjamin

    2013-01-01

    The Soil Moisture Active Passive (SMAP) mission, scheduled for launch by the end of 2014, is being developed to measure the soil moisture and soil freeze/thaw state on a global scale over a three-year period. The accuracy, resolution, and global coverage of SMAP measurements are invaluable across many science and applications disciplines including hydrology, climate, carbon cycle, and the meteorological, environment, and ecology applications communities. The SMAP observatory is composed of a despun bus and a spinning instrument platform that includes both a deployable 6 meter aperture low structural frequency Astromesh reflector and a spin control system. The instrument section has engendered challenging mechanical system issues associated with the antenna deployment, flexible antenna pointing in the context of a multitude of disturbances, spun section mass properties, spin control system development, and overall integration with the flight system on both mechanical and control system levels. Moreover, the multitude of organizations involved, including two major vendors providing the spin subsystem and reflector boom assembly plus the flight system mechanical and guidance, navigation, and control teams, has led to several unique system engineering challenges. Capturing the key physics associated with the function of the flight system has been challenging due to the many different domains that are applicable. Key interfaces and operational concepts have led to complex negotiations because of the large number of organizations that integrate with the instrument mechanical system. Additionally, the verification and validation concerns associated with the mechanical system have had required far-reaching involvement from both the flight system and other subsystems. The SMAP instrument mechanical systems engineering issues and their solutions are described in this paper.

  8. Single Crystal Silicon Instrument Mirrors

    NASA Technical Reports Server (NTRS)

    Bly, Vince

    2007-01-01

    The goals for the fabrication of single crystal silicon instrument mirrors include the following: 1) Develop a process for fabricating lightweight mirrors from single crystal silicon (SCS); 2) Modest lightweighting: 3X to 4X less than equivalent solid mirror; 3) High surface quality, better than lambda/40 RMS @ 633nm; 4) Significantly less expensive than current technology; and 5) Negligible distortion when cooled to cryogenic temperatures.

  9. Nuclear instrumentation cable end seal

    DOEpatents

    Cannon, Collins P.; Brown, Donald P.

    1979-01-01

    An improved coaxial end seal for hermetically sealed nuclear instrumentation cable exhibiting an improved breakdown pulse noise characteristic under high voltage, high temperature conditions. A tubular insulator body has metallized interior and exterior surface portions which are braze sealed to a center conductor and an outer conductive sheath. The end surface of the insulator body which is directed toward the coaxial cable to which it is sealed has a recessed surface portion within which the braze seal material terminates.

  10. LANDSAT D instrument module study

    NASA Technical Reports Server (NTRS)

    1976-01-01

    Spacecraft instrument module configurations which support an earth resource data gathering mission using a thematic mapper sensor were examined. The differences in size of these two experiments necessitated the development of two different spacecraft configurations. Following the selection of the best-suited configurations, a validation phase of design, analysis and modelling was conducted to verify feasibility. The chosen designs were then used to formulate definition for a systems weight, a cost range for fabrication and interface requirements for the thematic mapper (TM).

  11. Spatial Displays and Spatial Instruments

    NASA Technical Reports Server (NTRS)

    Ellis, Stephen R. (Editor); Kaiser, Mary K. (Editor); Grunwald, Arthur J. (Editor)

    1989-01-01

    The conference proceedings topics are divided into two main areas: (1) issues of spatial and picture perception raised by graphical electronic displays of spatial information; and (2) design questions raised by the practical experience of designers actually defining new spatial instruments for use in new aircraft and spacecraft. Each topic is considered from both a theoretical and an applied direction. Emphasis is placed on discussion of phenomena and determination of design principles.

  12. Video instrumentation for radionuclide angiocardiography.

    NASA Technical Reports Server (NTRS)

    Kriss, J. P.

    1973-01-01

    Two types of videoscintiscopes for performing radioisotopic angiocardiography with a scintillation camera are described, and use of these instruments in performing clinical studies is illustrated. Radionuclide angiocardiography is a simple, quick and accurate procedure recommended as a screening test for patients with a variety of congenital and acquired cardiovascular lesions. When performed in conjunction with coronary arterial catheterization, dynamic radionuclide angiography may provide useful information about regional myocardial perfusion. Quantitative capabilities greatly enhance the potential of this diagnostic tool.

  13. High-temperature borehole instrumentation

    SciTech Connect

    Dennis, B.R.; Koczan, S.P.; Stephani, E.L.

    1985-10-01

    A new method of extracting natural heat from the earth's crust was invented at the Los Alamos National Laboratory in 1970. It uses fluid pressures (hydraulic fracturing) to produce cracks that connect two boreholes drilled into hot rock formations of low initial permeability. Pressurized water is then circulated through this connected underground loop to extract heat from the rock and bring it to the surface. The creation of the fracture reservior began with drilling boreholes deep within the Precambrian basement rock at the Fenton Hill Test Site. Hydraulic fracturing, flow testing, and well-completion operations required unique wellbore measurements using downhole instrumentation systems that would survive the very high borehole temperatures, 320/sup 0/C (610/sup 0/F). These instruments were not available in the oil and gas industrial complex, so the Los Alamos National Laboratory initiated an intense program upgrading existing technology where applicable, subcontracting materials and equipment development to industrial manufactures, and using the Laboratory resource to develop the necessary downhole instruments to meet programmatic schedules. 60 refs., 11 figs.

  14. Multimodality Instrument for Tissue Characterization

    NASA Technical Reports Server (NTRS)

    Mah, Robert W. (Inventor); Andrews, Russell J. (Inventor)

    2000-01-01

    A system with multimodality instrument for tissue identification includes a computer-controlled motor driven heuristic probe with a multisensory tip is discussed. For neurosurgical applications, the instrument is mounted on a stereotactic frame for the probe to penetrate the brain in a precisely controlled fashion. The resistance of the brain tissue being penetrated is continually monitored by a miniaturized strain gauge attached to the probe tip. Other modality sensors may be mounted near the probe tip to provide real-time tissue characterizations and the ability to detect the proximity of blood vessels, thus eliminating errors normally associated with registration of pre-operative scans, tissue swelling, elastic tissue deformation, human judgement, etc., and rendering surgical procedures safer, more accurate, and efficient. A neural network, program adaptively learns the information on resistance and other characteristic features of normal brain tissue during the surgery and provides near real-time modeling. A fuzzy logic interface to the neural network program incorporates expert medical knowledge in the learning process. Identification of abnormal brain tissue is determined by the detection of change and comparison with previously learned models of abnormal brain tissues. The operation of the instrument is controlled through a user friendly graphical interface. Patient data is presented in a 3D stereographics display. Acoustic feedback of selected information may optionally be provided. Upon detection of the close proximity to blood vessels or abnormal brain tissue, the computer-controlled motor immediately stops probe penetration.

  15. Innovative Technology in Hearing Instruments

    PubMed Central

    2011-01-01

    Hearing instrument technology research is almost entirely focused on the projected needs of the consumer market in the developed world. However, two thirds of the world’s population with hearing impairment live in developing countries and this proportion will increase in future, given present demographic trends. In developing regions, amplification and other hearing health needs may differ from those in industrialized nations, for cultural, health, or economic reasons. World Health Organization estimates indicate that at present only a small percentage of individuals in developing countries who are in need of amplification have access to hearing aid provision. New technologies, such as trainable hearing aids, advanced noise reduction algorithms, feedback reduction circuitry, nano coatings for hearing aid components, and innovative power options, may offer considerable potential benefits, both for individuals with hearing impairment in developing countries and for those who provide hearing health care services in these regions. This article considers the possible supporting role of innovative hearing instrument technologies in the provision of affordable hearing health care services in developing countries and highlights the need for research that considers the requirements of the majority of the world population in need of hearing instrument provision. PMID:22068223

  16. Geotechnical instrumentation for repository shafts

    SciTech Connect

    Lentell, R.L.; Byrne, J.

    1993-09-01

    The US Congress passed the Nuclear Waste Policy Act in 1980, which required that three distinctly different geologic media be investigated as potential candidate sites for the permanent disposal of high-level nuclear waste. The three media that were selected for study were basalt (WA), salt (TX, LA, MS, UT), and tuff (NV). Preliminary Exploratory Shaft Facilities (ESF) designs were prepared for seven candidate salt sites, including bedded and domal salt environments. A bedded-salt site was selected in Deaf Smith County, TX for detailed site characterization studies and ESF Final Design. Although Congress terminated the Salt Repository Program in 1988, Final Design for the Deaf Smith ESF was completed, and much of the design rationale can be applied to subsequent deep repository shafts. This paper presents the rationale for the geotechnical instrumentation that was designed for construction and operational performance monitoring of the deep shafts of the in-situ test facility. The instrumentation design described herein can be used as a general framework in designing subsequent instrumentation programs for future high-level nuclear waste repository shafts.

  17. The Polar Plasma Wave Instrument

    NASA Technical Reports Server (NTRS)

    Gurnett, D. A.; Persoon, A. M.; Randall, R. F.; Odem, D. L.; Remington, S. L.; Averkamp, T. F.; Debower, M. M.; Hospodarsky, G. B.; Huff, R. L.; Kirchner, D. L.

    1995-01-01

    The Plasma Wave Instrument on the Polar spacecraft is designed to provide measurements of plasma waves in the Earth's polar regions over the frequency range from 0.1 Hz to 800 kHz. Three orthogonal electric dipole antennas are used to detect electric fields, two in the spin plane and one aligned along the spacecraft spin axis. A magnetic loop antenna and a triaxial magnetic search coil antenna are used to detect magnetic fields. Signals from these antennas are processed by five receiver systems: a wideband receiver, a high-frequency waveform receiver, a low-frequency waveform receiver, two multichannel analyzers; and a pair of sweep frequency receivers. Compared to previous plasma wave instruments, the Polar plasma wave instrument has several new capabilities. These include (1) an expanded frequency range to improve coverage of both low- and high-frequency wave phenomena, (2) the ability to simultaneously capture signals from six orthogonal electric and magnetic field sensors, and (3) a digital wideband receiver with up to 8-bit resolution and sample rates as high as 249k samples s(exp -1).

  18. High-temperature borehole instrumentation

    NASA Astrophysics Data System (ADS)

    Dennis, B. R.; Koczan, S. P.; Stephani, E. L.

    1985-10-01

    A new method of extracting natural heat from the Earth's crust was invented at the Los Alamos National Laboratory in 1970. It uses fluid pressures (hydraulic fracturing) to produce cracks that connect two boreholes drilled into hot rock formations of low initial permeability. Pressurized water is then circulated through this connected underground loop to extract heat from the rock and bring it to the surface. The creation of the fracture reservior began with drilling boreholes deep within the Precambrian basement rock at the Fenton Hill Test Site. Hydraulic fracturing, flow testing, and well-completion operations required unique wellbore measurements using downhole instrumentation systems that would survive the very high borehole temperatures, 320(0)C (610(0)F). These instruments were not available in the oil and gas industrial complex, so the Los Alamos National Laboratory initiated an intense program upgrading existing technology where applicable, subcontracting materials and equipment development to industrial manufactures, and using the Laboratory resources to develop the necessary downhole instruments to meet programmatic schedules.

  19. ({sup 3}He,t) reaction on the double {beta} decay nucleus {sup 48}Ca and the importance of nuclear matrix elements

    SciTech Connect

    Grewe, E.-W.; Frekers, D.; Rakers, S.; Baeumer, C.; Dohmann, H.; Thies, J.; Adachi, T.; Fujita, Y.; Shimbara, Y.; Botha, N. T.; Fujita, H.; Hatanaka, K.; Nakanishi, K.; Sakemi, Y.; Shimizu, Y.; Tameshige, Y.; Tamii, A.; Negret, A.; Popescu, L.; Neveling, R.

    2007-11-15

    High-resolution ({sup 3}He,t) measurements on the double {beta}-decay ({beta}{beta}) nucleus {sup 48}Ca have been performed at RCNP (Osaka, Japan) to determine Gamow-Teller (GT{sup -}) transitions to the nucleus {sup 48}Sc, which represents the intermediate nucleus in the second-order perturbative description of the {beta}{beta} decay. At a bombarding energy of E{sub {sup 3}He}=420 MeV an excitation energy resolution of 40 keV was achieved. The measurements were performed at two angle positions of the Grand Raiden Spectrometer (GRS): 0 deg. and 2.5 deg. The results of both settings were combined to achieve angular distributions, by which the character of single transitions could be determined. To characterize the different multipoles, theoretical angular distributions for states with J{sup {pi}}=1{sup +},2{sup +},2{sup -}, and 3{sup +} were calculated using the distorted-wave Born approximation (DWBA) Code DW81. The GT{sup -} strength was extracted up to E{sub x}=7 MeV and combined with corresponding GT{sup +} strength deduced from the {sup 48}Ti(d,{sup 2}He){sup 48}Sc data to calculate the low-energy part of the {beta}{beta}-decay matrix element for the {sup 48}Ca 2{nu}{beta}{beta} decay. We show that after applying trivial momentum corrections to the ({sup 3}He,t) spectrum, the two reaction probes (p,n) and ({sup 3}He,t) reveal a spectral response to an impressively high degree of similarity in the region of low momentum transfer.

  20. Aeronautic Instruments. Section VI : Aerial Navigation and Navigating Instruments

    NASA Technical Reports Server (NTRS)

    Eaton, H N

    1923-01-01

    This report outlines briefly the methods of aerial navigation which have been developed during the past few years, with a description of the different instruments used. Dead reckoning, the most universal method of aerial navigation, is first discussed. Then follows an outline of the principles of navigation by astronomical observation; a discussion of the practical use of natural horizons, such as sea, land, and cloud, in making extant observations; the use of artificial horizons, including the bubble, pendulum, and gyroscopic types. A description is given of the recent development of the radio direction finder and its application to navigation.

  1. Amine Directed Pd(II)-Catalyzed C-H Activation-Intramolecular Amination of N-Het(aryl)/Acyl Enaminonitriles and Enaminones: An Approach towards Multisubstituted Indoles and Heterofused Pyrroles.

    PubMed

    Yugandar, Somaraju; Konda, Saidulu; Ila, Hiriyakkanavar

    2016-03-01

    An efficient route to multisubstituted indoles has been developed through intramolecular oxidative C-H activation-amination of readily available 2-(het)aryl-3-(het)aryl/alkyl-3-(het)aryl/acylaminoacrylonitrile/enaminone precursors in the presence of either palladium acetate/cupric acetate catalytic system under oxygen atmosphere or palladium acetate/silver carbonate in the presence of pivalic acid as additive. The method is compatible with a diverse range of substituents on the aryl ring as well as at the 2- and 3-positions of the indole ring. The versatility of this method was further demonstrated by elaborating it for the synthesis of heterofused pyrroles such as thieno[2,3-b]pyrroles, thieno[3,2-b]pyrroles, pyrrolo[2,3-b]indoles, and pyrrolo[2,3-b]pyridines in good yields. Probable mechanisms for the formation of these indoles have been suggested. PMID:26842134

  2. Optimal calibration of instrumented treadmills using an instrumented pole.

    PubMed

    Sloot, L H; Houdijk, H; van der Krogt, M M; Harlaar, J

    2016-08-01

    Calibration of instrumented treadmills is imperative for accurate measurement of ground reaction forces and center of pressure (COP). A protocol using an instrumented pole has been shown to considerably increase force and COP accuracy. This study examined how this protocol can be further optimized to maximize accuracy, by varying the measurement time and number of spots, using nonlinear approaches to calculate the calibration matrix and by correcting for potential inhomogeneity in the distribution of COP errors across the treadmill's surface. The accuracy increased with addition of spots and correction for the inhomogeneous distribution across the belt surface, decreased with reduction of measurement time, and did not improve by including nonlinear terms. Most of these methods improved the overall accuracy only to a limited extent, suggesting that the maximal accuracy is approached given the treadmill's inherent mechanical limitations. However, both correction for position dependence of the accuracy as well as its optimization within the walking area are found to be valuable additions to the standard calibration process. PMID:27180211

  3. Use of Electrical and Electronic Instruments

    ERIC Educational Resources Information Center

    Mosbacher, C. J.; Thomas, E. J.

    1977-01-01

    Presents results of a trend survey of the present and planned use of electrical and electronic instruments. Microprocessors were found to have the highest predicted growth rate of all instruments included in the survey. (SL)

  4. 14 CFR 27.1549 - Powerplant instruments.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... § 27.1549 Powerplant instruments. For each required powerplant instrument, as appropriate to the type... restricted because of excessive vibration stresses must be marked with red arcs or red lines; and (e)...

  5. 14 CFR 27.1549 - Powerplant instruments.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... § 27.1549 Powerplant instruments. For each required powerplant instrument, as appropriate to the type... restricted because of excessive vibration stresses must be marked with red arcs or red lines; and (e)...

  6. Encapsulation process sterilizes and preserves surgical instruments

    NASA Technical Reports Server (NTRS)

    Montgomery, L. C.; Morelli, F. A.

    1964-01-01

    Ethylene oxide is blended with an organic polymer to form a sterile material for encapsulating surgical instruments. The material does not bond to metal and can be easily removed when the instruments are needed.

  7. Regional Instrumentation Facilities Established by NSF.

    ERIC Educational Resources Information Center

    Analytical Chemistry, 1979

    1979-01-01

    This article describes the six regional instrumentation facilities established by the National Science Foundation. These centers make available to scientists state-of-the-art instrumentation such as: gas chromatographs; lasers; NMR spectrometers; X-rays; and others. (CS)

  8. An Instrument to Aid in Assessing Editorials.

    ERIC Educational Resources Information Center

    Burkhalter, Nancy

    1995-01-01

    Presents a primary-trait scoring instrument intended for journalism teachers to use in assessing students' editorials by breaking down the analysis into three essential components: claims, data, and warrants. Applies the instrument to two student essays. (SR)

  9. A portable luminescence dating instrument

    NASA Astrophysics Data System (ADS)

    Kook, M. H.; Murray, A. S.; Lapp, T.; Denby, P. H.; Ankjærgaard, C.; Thomsen, K.; Jain, M.; Choi, J. H.; Kim, G. H.

    2011-06-01

    We describe a portable luminescence reader suitable for use in remote localities in the field. The instrument weighs about 8 kg and is based around a 30 mm bialkali photomultiplier detecting signals through a glass filter centered on 340 nm. Stimulation is by 470 nm blue LEDs (24 W in total) operating in both continuous wave and pulsed mode; photon counting can be gated such that it is active only during the pulse off-period. There are also two bleaching light sources (470 nm, 5 W and 940 nm, 3 W), and the luminescence signals can be regenerated using a cold-cathode 30 kV X-ray tube, delivering ˜0.06 Gy.s -1. The three position sampling device has a heating element under each sampling position, able to heat the sample at 3 °C.s -1 up to at least 250 °C. The sampler can be inserted into unconsolidated sediments, and is designed to prevent exposure of the mineral grains to ambient light during sampling. The performance of the instrument in terms of sensitivity and reproducibility is comparable to that of the standard bench-top laboratory TL/OSL Risø reader. We show that the portable luminescence reader is able to measure accurately an ˜20 Gy quartz burial dose in a natural (unpretreated, no mineral separation) sandy sediment. We also show that, because of the configuration of the measurement head, the portable reader can be used to measure radioluminescence at elevated temperature in the presence of stimulation light; this facility is not available on conventional bench-top instruments. It is concluded that the portable luminescence reader can be used to accurately determine the quartz burial dose in loose sandy sediments in the field, without sample preparation or darkroom facilities.

  10. Multimodality instrument for tissue characterization

    NASA Technical Reports Server (NTRS)

    Mah, Robert W. (Inventor); Andrews, Russell J. (Inventor)

    2004-01-01

    A system with multimodality instrument for tissue identification includes a computer-controlled motor driven heuristic probe with a multisensory tip. For neurosurgical applications, the instrument is mounted on a stereotactic frame for the probe to penetrate the brain in a precisely controlled fashion. The resistance of the brain tissue being penetrated is continually monitored by a miniaturized strain gauge attached to the probe tip. Other modality sensors may be mounted near the probe tip to provide real-time tissue characterizations and the ability to detect the proximity of blood vessels, thus eliminating errors normally associated with registration of pre-operative scans, tissue swelling, elastic tissue deformation, human judgement, etc., and rendering surgical procedures safer, more accurate, and efficient. A neural network program adaptively learns the information on resistance and other characteristic features of normal brain tissue during the surgery and provides near real-time modeling. A fuzzy logic interface to the neural network program incorporates expert medical knowledge in the learning process. Identification of abnormal brain tissue is determined by the detection of change and comparison with previously learned models of abnormal brain tissues. The operation of the instrument is controlled through a user friendly graphical interface. Patient data is presented in a 3D stereographics display. Acoustic feedback of selected information may optionally be provided. Upon detection of the close proximity to blood vessels or abnormal brain tissue, the computer-controlled motor immediately stops probe penetration. The use of this system will make surgical procedures safer, more accurate, and more efficient. Other applications of this system include the detection, prognosis and treatment of breast cancer, prostate cancer, spinal diseases, and use in general exploratory surgery.

  11. The hen's egg chorioallantoic membrane (HET-CAM) test to predict the ophthalmic irritation potential of a cysteamine-containing gel: Quantification using Photoshop® and ImageJ.

    PubMed

    McKenzie, Barbara; Kay, Graeme; Matthews, Kerr H; Knott, Rachel M; Cairns, Donald

    2015-07-25

    A modified hen's egg chorioallantoic membrane (HET-CAM) test has been developed, combining ImageJ analysis with Adobe(®) Photoshop(®). The irritation potential of an ophthalmic medicine can be quantified using this method, by monitoring damage to blood vessels. The evaluation of cysteamine containing hyaluronate gel is reported. The results demonstrated that the novel gel formulation is non-irritant to the ocular tissues, in line with saline solution (negative control). In conclusion, the modification of the established HET-CAM test can quantify the damage to minute blood vessels. These results offer the possibility to formulate cysteamine in an ocular applicable gel formulation.

  12. Compact Instruments Measure Heat Potential

    NASA Technical Reports Server (NTRS)

    2009-01-01

    Based in Huntsville, Alabama, AZ Technology Inc. is a woman- and veteran-owned business that offers expertise in electromechanical-optical design and advanced coatings. AZ Technology has received eight Small Business Innovation Research (SBIR) contracts with Marshall Space Flight Center for the development of spectral reflectometers and the measurement of surface thermal properties. The company uses a variety of measurement services and instruments, including the Spectrafire, a portable spectral emissometer it used to assist General Electric with the design of its award-winning Giraffe Warmer for neonatal intensive care units.

  13. Tevatron instrumentation: boosting collider performance

    SciTech Connect

    Shiltsev, Vladimir; Jansson, Andreas; Moore, Ronald; /Fermilab

    2006-05-01

    The Tevatron in Collider Run II (2001-present) is operating with six times more bunches, many times higher beam intensities and luminosities than in Run I (1992-1995). Beam diagnostics were crucial for the machine start-up and the never-ending luminosity upgrade campaign. We present the overall picture of the Tevatron diagnostics development for Run II, outline machine needs for new instrumentation, present several notable examples that led to Tevatron performance improvements, and discuss the lessons for the next big machines--LHC and ILC.

  14. Experimenting with brass musical instruments

    NASA Astrophysics Data System (ADS)

    Lo Presto, Michael C.

    2003-07-01

    With the aid of microcomputer hardware and software for the introductory physics laboratory, I have developed several experiments dealing with the properties of brass musical instruments that could be used when covering sound anywhere from an introductory physics laboratory to a course in musical acoustics, or even independent studies. The results of these experiments demonstrate in a quantitative fashion the effects of the mouthpiece and bell on the frequencies of the sound waves and thus the musical pitches produced. Most introductory sources only discuss these effects qualitatively.

  15. pH Optrode Instrumentation

    NASA Technical Reports Server (NTRS)

    Tabacco, Mary Beth; Zhou, Quan

    1995-01-01

    pH-sensitive chromophoric reagents immobilized in porous optical fibers. Optoelectronic instrumentation system measures acidity or alkalinity of aqueous nutrient solution. Includes one or more optrodes, which are optical-fiber chemical sensors, in sense, analogous to electrodes but not subject to some of spurious effects distorting readings taken by pH electrodes. Concept of optrodes also described in "Ethylene-Vapor Optrodes" (KSC-11579). pH optrode sensor head, with lead-in and lead-out optical fibers, convenient for monitoring solutions located away from supporting electronic equipment.

  16. Starting a Small Instrument Company

    NASA Astrophysics Data System (ADS)

    Warburton, W. K.

    1997-03-01

    The author is now the owner of an 8 person company that develops specialized electronics to support the detectors used at synchrotron radiation facilities and is spinning this expertise off into developing spectrometry instruments for specialized medical markets. This talk will begin with a short history illustrating the random walk processes leading to the present situation and then consider some of the issues which a small company must deal with in order to survive. From this perspective, the author will then extract a list of steps the prospective physicist/entreprenuer can take, while still a student or post-doc, to prepare for success in growing a small business.

  17. Instrumentation development for the EUVE

    NASA Astrophysics Data System (ADS)

    Finley, D.

    1980-06-01

    The prototype mirror was successfully replated with a thick layer of nickel and diamond turned again. Optimization of the sensitivity of the instruments was studied with emphasis on the filter material, and on the available telemetry. The JHU Preliminary Project Definition Document was critically analyzed. Further studies of the electron cloud distribution produced by a channel plate were performed, and a wedge and strip anode with 17 quartets per inch was shown to image with better than 0.5% linearity. Half the microchannel plates being used in the lifetest completed initial processing and are in the lifetest vacuum chamber.

  18. Instrument Deployment for Mars Rovers

    NASA Technical Reports Server (NTRS)

    Pedersen, Liam; Bualat, Maria; Kunz, C.; Lee, Susan; Sargent, Randy; Washington, Rich; Wright, Anne; Clancy, Daniel (Technical Monitor)

    2002-01-01

    Future Mars rovers, such as the planned 2009 MSL rover, require sufficient autonomy to robustly approach rock targets and place an instrument in contact with them. It took the 1997 Sojourner Mars rover between 3 and 5 communications cycles to accomplish this. This paper describes the technologies being developed and integrated onto the NASA Ames K9 prototype Mars rover to both accomplish this in one cycle, and to extend the complexity and duration of operations that a Mars rover can accomplish without intervention from mission control.

  19. MEMS Actuators for Tuning Nanometer-scale Airgaps in Heterostructures and Optical Instrumentation for Glacier Ice Studies

    NASA Astrophysics Data System (ADS)

    Chan, Wing Shan

    MEMS Actuators for Tuning Nanometer-scale Airgaps in Heterostructures: We developed a new actuator microstructure to control the spacing between closely spaced surfaces. Creating and controlling nanometer gaps is of interest in areas such as plasmonics and quantum electronics. For example, energy states in quantum well heterostructures can be tuned by adjusting the physical coupling distance between wells. Unfortunately, such an application calls for active control of a nano-scale air gap between surfaces which are orders of magnitude larger, which is difficult due to stiction forces. A vertical electrostatic wedge actuator was designed to control the air gap between two closely spaced quantum wells in a collapsed cantilever structure. A six-mask fab- rication process was developed and carried out on an InGaAs/InP quantum well het- erostructure on an InP substrate. Upon actuation, the gap spacing between the surfaces was tuned over a maximum range of 55 nm from contact with an applied voltage of 60 V. Challenges in designing and fabricating the device are discussed. Optical Instrumentation for Glacier Ice Studies: We explored new optical instrumentation for glacier ice studies. Glacier ice, such as that of the Greenland and Antarctic ice sheets, is formed by the accumulation of snowfall over hundreds of thousands of years. Not all snowfalls are the same. Their isotopic compositions vary according to the planet's climate at the time, and may contain part of the past atmosphere. The physical properties and chemical content of the ice are therefore proxies of Earth's climate history. In this work, new optical methods and instrumentation based on light scattering and polarization were developed to more efficiently study glacier ice. Field deployments in Antarctica of said instrumentation and results acquired are presented.

  20. Mariner Jupiter/Saturn infrared instrument study

    NASA Technical Reports Server (NTRS)

    1972-01-01

    The Mariner Jupiter/Saturn infrared instrumentation conceptual design study was conducted to determine the physical and operational characteristics of the instruments needed to satisfy the experiment science requirements. The design of the instruments is based on using as many proven concepts as possible. Many design features are taken from current developments such as the Mariner, Pioneer 10, Viking Orbiter radiometers, and Nimbus D spectrometer. Calibration techniques and error analysis for the instrument system are discussed.

  1. Optoelectronic Instruments For Analysis Of Surface Defects

    NASA Technical Reports Server (NTRS)

    Collins, J. David; Mueller, Robert P.; Davis, Richard M.; Gleman, Stuart M.; Hallberg, Carl G.; Thayer, Stephen W.; Thompson, David L.; Thompson, James E.

    1995-01-01

    Family of portable optoelectronic instruments developed to facilitate inspection of surface flaws like gouges, scratches, raised metal, and dents on large metal workpieces subject to surface-finish requirements. Instrument brought to workpiece and semiautomatically makes electronic record of three-dimensional shape of flaw. Entire inspection process takes only minutes. Prototype instrument includes structured-light microscope. Concept involves projection of known pattern of light onto surface inspected. Topography of surface determined from distortion of pattern as viewed through instrument.

  2. Chemical Instrumentation for the Visually Handicapped.

    ERIC Educational Resources Information Center

    Anderson, James L.

    1982-01-01

    Describes a simple, relatively inexpensive, and easily implemented approach for introducing visually handicapped students to chemical instrumentation via experiments on operational amplifiers as examples of some of the electronic building blocks of chemical instrumentation. The approach is applicable to other chemical instruments having electrical…

  3. 21 CFR 864.5400 - Coagulation instrument.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Coagulation instrument. 864.5400 Section 864.5400....5400 Coagulation instrument. (a) Identification. A coagulation instrument is an automated or semiautomated device used to determine the onset of clot formation for in vitro coagulation studies....

  4. 21 CFR 864.5400 - Coagulation instrument.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Coagulation instrument. 864.5400 Section 864.5400....5400 Coagulation instrument. (a) Identification. A coagulation instrument is an automated or semiautomated device used to determine the onset of clot formation for in vitro coagulation studies....

  5. 21 CFR 864.5400 - Coagulation instrument.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Coagulation instrument. 864.5400 Section 864.5400....5400 Coagulation instrument. (a) Identification. A coagulation instrument is an automated or semiautomated device used to determine the onset of clot formation for in vitro coagulation studies....

  6. 21 CFR 864.5400 - Coagulation instrument.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Coagulation instrument. 864.5400 Section 864.5400....5400 Coagulation instrument. (a) Identification. A coagulation instrument is an automated or semiautomated device used to determine the onset of clot formation for in vitro coagulation studies....

  7. 21 CFR 864.5400 - Coagulation instrument.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Coagulation instrument. 864.5400 Section 864.5400....5400 Coagulation instrument. (a) Identification. A coagulation instrument is an automated or semiautomated device used to determine the onset of clot formation for in vitro coagulation studies....

  8. 14 CFR 29.1381 - Instrument lights.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Instrument lights. 29.1381 Section 29.1381 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY ROTORCRAFT Equipment Lights § 29.1381 Instrument lights. The instrument...

  9. 14 CFR 27.1381 - Instrument lights.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Instrument lights. 27.1381 Section 27.1381 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: NORMAL CATEGORY ROTORCRAFT Equipment Lights § 27.1381 Instrument lights. The instrument...

  10. 14 CFR 29.1381 - Instrument lights.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Instrument lights. 29.1381 Section 29.1381 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY ROTORCRAFT Equipment Lights § 29.1381 Instrument lights. The instrument...

  11. 14 CFR 27.1381 - Instrument lights.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Instrument lights. 27.1381 Section 27.1381 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: NORMAL CATEGORY ROTORCRAFT Equipment Lights § 27.1381 Instrument lights. The instrument...

  12. Earth Viewing Applications Laboratory (EVAL). Instrument catalog

    NASA Technical Reports Server (NTRS)

    1976-01-01

    There were 87 instruments described that are used in earth observation, with an additional 51 instruments containing references to programs and their major functions. These instruments were selected from such sources as: (1) earth observation flight program, (2) operational satellite improvement programs, (3) advanced application flight experiment program, (4) shuttle experiment definition program, and (5) earth observation aircraft program.

  13. Are Musical Instrument Gender Associations Changing?

    ERIC Educational Resources Information Center

    Abeles, Hal

    2009-01-01

    The researcher sought to examine gender associations across three decades to determine if changes in the sex stereotyping of musical instruments has occurred. First, the study examined the paired comparison gender-instrument rankings of 180 college students. The results confirmed a reduction of instrument gender associations reported in the 1990s.…

  14. 14 CFR 27.1381 - Instrument lights.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Instrument lights. 27.1381 Section 27.1381 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: NORMAL CATEGORY ROTORCRAFT Equipment Lights § 27.1381 Instrument lights. The instrument...

  15. 14 CFR 29.1381 - Instrument lights.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Instrument lights. 29.1381 Section 29.1381 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY ROTORCRAFT Equipment Lights § 29.1381 Instrument lights. The instrument...

  16. 14 CFR 27.1381 - Instrument lights.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Instrument lights. 27.1381 Section 27.1381 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: NORMAL CATEGORY ROTORCRAFT Equipment Lights § 27.1381 Instrument lights. The instrument...

  17. 14 CFR 29.1381 - Instrument lights.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Instrument lights. 29.1381 Section 29.1381 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY ROTORCRAFT Equipment Lights § 29.1381 Instrument lights. The instrument...

  18. 14 CFR 27.1381 - Instrument lights.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Instrument lights. 27.1381 Section 27.1381 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: NORMAL CATEGORY ROTORCRAFT Equipment Lights § 27.1381 Instrument lights. The instrument...

  19. 14 CFR 29.1381 - Instrument lights.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Instrument lights. 29.1381 Section 29.1381 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY ROTORCRAFT Equipment Lights § 29.1381 Instrument lights. The instrument...

  20. Industrial Instrument Mechanic. Occupational Analyses Series.

    ERIC Educational Resources Information Center

    Dean, Ann; Zagorac, Mike; Bumbaka, Nick

    This analysis covers tasks performed by an industrial instrument mechanic, an occupational title some provinces and territories of Canada have also identified as industrial instrumentation and instrument mechanic. A guide to analysis discusses development, structure, and validation method; scope of the occupation; trends; and safety. To facilitate…

  1. 47 CFR 73.258 - Indicating instruments.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 4 2012-10-01 2012-10-01 false Indicating instruments. 73.258 Section 73.258 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES RADIO BROADCAST SERVICES FM Broadcast Stations § 73.258 Indicating instruments. (a) Each FM broadcast station shall be equipped with indicating instruments...

  2. 14 CFR 27.1549 - Powerplant instruments.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Powerplant instruments. 27.1549 Section 27... § 27.1549 Powerplant instruments. For each required powerplant instrument, as appropriate to the type of instrument— (a) Each maximum and, if applicable, minimum safe operating limit must be marked...

  3. 47 CFR 73.58 - Indicating instruments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false Indicating instruments. 73.58 Section 73.58... Broadcast Stations § 73.58 Indicating instruments. (a) Each AM broadcast station must be equipped with indicating instruments which conform with the specifications described in § 73.1215 for determining power...

  4. 47 CFR 73.688 - Indicating instruments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false Indicating instruments. 73.688 Section 73.688... Television Broadcast Stations § 73.688 Indicating instruments. (a) Each TV broadcast station shall be equipped with indicating instruments which conform with the specifications described in § 73.1215...

  5. 14 CFR 29.1549 - Powerplant instruments.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Powerplant instruments. 29.1549 Section 29... Placards § 29.1549 Powerplant instruments. For each required powerplant instrument, as appropriate to the type of instruments— (a) Each maximum and, if applicable, minimum safe operating limit must be...

  6. 47 CFR 73.558 - Indicating instruments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false Indicating instruments. 73.558 Section 73.558... Noncommercial Educational FM Broadcast Stations § 73.558 Indicating instruments. The requirements for indicating instruments described in § 73.258 are applicable to all educational FM broadcast stations licensed with...

  7. ICFA Instrumentation Bulletin, Volume 14, Spring 1997

    SciTech Connect

    1997-07-01

    The publication of the ICFA Instrumentation Bulletin is an activity of the Panel on Future Innovation and Development of ICFA (International Committee for Future Accelerators). The Bulletin reports on research and progress in the field of instrumentation with emphasis on application in the field of high-energy physics. It encourages issues of generic instrumentation.

  8. Adult Perspectives of Learning Musical Instruments

    ERIC Educational Resources Information Center

    Roulston, Kathryn; Jutras, Peter; Kim, Seon Joo

    2015-01-01

    This article reports findings from a qualitative study of adults' perceptions and experiences of learning musical instruments. Conducted in the south-east United States, 15 adults who were learning instruments were recruited via community music groups and private instrumental teachers. Analysis of transcripts of semi-structured interviews…

  9. ICFA Instrumentation Bulletin, Volume 13, Fall 1996

    SciTech Connect

    1996-12-01

    The publication of the ICFA Instrumentation Bulletin is an activity of the Panel on Future Innovation and Development of ICFA (International Committee for Future Accelerators). The Bulletin reports on research and progress in the field of instrumentation with emphasis on application in the field of high-energy physics. It encourages issues of generic instrumentation.

  10. High energy gamma ray balloon instrument

    NASA Technical Reports Server (NTRS)

    Thompson, D. J.; Baker, R. G.; Bertsch, D. L.; Chesney, J. R.; Derdeyn, S. M.; Ehrmann, C. H.; Fichtel, C. E.; Hunter, S. D.; Jacques, J. S.; Laubenthal, N. A.

    1985-01-01

    The High Energy Gamma Ray Balloon Instrument was built in part to verify certain subsystems' performance for the Energetic Gamma Ray Experiment Telescope (EGRET) instrument, the high energy telescope to be carried on the Gamma Ray Observatory. This paper describes the instrument, the performance of some subsystems, and some relevant results.

  11. Bicep2. III. INSTRUMENTAL SYSTEMATICS

    SciTech Connect

    Ade, P. A. R.; Aikin, R. W.; Bock, J. J.; Brevik, J. A.; Filippini, J. P.; Golwala, S. R.; Hildebrandt, S. R.; Barkats, D.; Benton, S. J.; Bischoff, C. A.; Buder, I.; Karkare, K. S.; Bullock, E.; Dowell, C. D.; Duband, L.; Fliescher, S.; Halpern, M.; Hasselfield, M.; Hilton, G. C.; Irwin, K. D.; Collaboration: Bicep2 Collaboration; and others

    2015-12-01

    In a companion paper, we have reported a >5σ detection of degree scale B-mode polarization at 150 GHz by the Bicep2 experiment. Here we provide a detailed study of potential instrumental systematic contamination to that measurement. We focus extensively on spurious polarization that can potentially arise from beam imperfections. We present a heuristic classification of beam imperfections according to their symmetries and uniformities, and discuss how resulting contamination adds or cancels in maps that combine observations made at multiple orientations of the telescope about its boresight axis. We introduce a technique, which we call “deprojection,” for filtering the leading order beam-induced contamination from time-ordered data, and show that it reduces power in Bicep2's actual and null-test BB spectra consistent with predictions using high signal-to-noise beam shape measurements. We detail the simulation pipeline that we use to directly simulate instrumental systematics and the calibration data used as input to that pipeline. Finally, we present the constraints on BB contamination from individual sources of potential systematics. We find that systematics contribute BB power that is a factor of ∼10× below Bicep2's three-year statistical uncertainty, and negligible compared to the observed BB signal. The contribution to the best-fit tensor/scalar ratio is at a level equivalent to r = (3–6) × 10{sup −3}.

  12. BICEP2 III: Instrumental systematics

    SciTech Connect

    Ade, P. A. R.

    2015-11-23

    In a companion paper, we have reported a >5σ detection of degree scale B-mode polarization at 150 GHz by the Bicep2 experiment. Here we provide a detailed study of potential instrumental systematic contamination to that measurement. We focus extensively on spurious polarization that can potentially arise from beam imperfections. We present a heuristic classification of beam imperfections according to their symmetries and uniformities, and discuss how resulting contamination adds or cancels in maps that combine observations made at multiple orientations of the telescope about its boresight axis. We introduce a technique, which we call "deprojection," for filtering the leading order beam-induced contamination from time-ordered data, and show that it reduces power in Bicep2's actual and null-test BB spectra consistent with predictions using high signal-to-noise beam shape measurements. We detail the simulation pipeline that we use to directly simulate instrumental systematics and the calibration data used as input to that pipeline. Finally, we present the constraints on BB contamination from individual sources of potential systematics. We find that systematics contribute BB power that is a factor of ~10× below Bicep2's three-year statistical uncertainty, and negligible compared to the observed BB signal. Lastly, the contribution to the best-fit tensor/scalar ratio is at a level equivalent to r = (3–6) × 10–3.

  13. Instrumentation for mass spectrometry: 1997

    SciTech Connect

    McLuckey, S.A.

    1997-08-01

    All mass spectrometry experiments involve the manipulation of material, an interface with the mass spectrometer, ionization, ion manipulation/analysis, detection and data collection/reduction. Each of these elements involve instrumentation. The wide range of species now amenable to mass spectrometry and the diverse areas of physical science in which it plays a role have led to a seemingly unlimited array of instrumental combinations. However, only a limited number of mass analyzers, and their combinations, dominate. The dominant analyzers include time-of-flight, Fourier transform ion cyclotron resonance, the Paul trap, the mass filter, and the sector mass spectrometer. Why there are so few (or so many, depending upon one`s point of view) can be understood upon consideration of a set of mass analyzer figures of merit. These include mass resolution, mass accuracy, mass range, dynamic range, abundance sensitivity, precision, efficiency, speed, MS{sup n} capability, compatibility with the ionizer, cost, and size. The most appropriate form of mass spectrometry is determined by the priorities of the particular measurement placed on the various mass analyzer characteristics and the relative strengths of the analyzers in meeting the requirements. Each of the analyzer types has a unique set of figures of merit that makes it optimally suited for particular applications. This paper discusses these figures of merit, provides data illustrating recent developments for each analyzer type, and gives the figures of merit of each type of analyzer as they stand in 1997. 101 refs., 24 figs.

  14. The TROPOspheric Monitoring Instrument (TROPOMI)

    NASA Astrophysics Data System (ADS)

    Veefkind, Pepijn; Kleipool, Quintus; Aben, Ilse; Levelt, Pieternel

    2015-04-01

    The Copernicus Sentinel 5 Precursor (S5P), scheduled for launch in 2016, is the first of the sentinels dedicated to monitoring of the atmospheric composition. The main application areas of the mission are air quality, climate and the ozone layer. The single payload of the S5P mission is TROPOspheric Monitoring Instrument (TROPOMI). TROPOMI is a nadir viewing shortwave spectrometer that will measure in the UV-visible wavelength range (270-500 nm), the near infrared (710-770 nm) and the shortwave infrared (2314-2382 nm). TROPOMI will have an unprecedented spatial resolution of about 7x7 km2 at nadir. The spatial resolution is combined with a wide swath to allow for daily global coverage. The high spatial resolution serves two goals: (1) emissions sources can be detected with more accuracy and (2) the number of cloud-free ground pixels will increase substantially. The TROPOMI/S5P geophysical (Level 2) data products include nitrogen dioxide, carbon monoxide, ozone (total column, tropospheric column & profile), methane, sulphur dioxide, formaldehyde and aerosol and cloud parameters. In this contribution we will present the TROPOMI instrument performance and the new science opportunities that it will enable.

  15. Method for improving instrument response

    DOEpatents

    Hahn, David W.; Hencken, Kenneth R.; Johnsen, Howard A.; Flower, William L.

    2000-01-01

    This invention pertains generally to a method for improving the accuracy of particle analysis under conditions of discrete particle loading and particularly to a method for improving signal-to-noise ratio and instrument response in laser spark spectroscopic analysis of particulate emissions. Under conditions of low particle density loading (particles/m.sup.3) resulting from low overall metal concentrations and/or large particle size uniform sampling can not be guaranteed. The present invention discloses a technique for separating laser sparks that arise from sample particles from those that do not; that is, a process for systematically "gating" the instrument response arising from "sampled" particles from those responses which do not, is dislosed as a solution to his problem. The disclosed approach is based on random sampling combined with a conditional analysis of each pulse. A threshold value is determined for the ratio of the intensity of a spectral line for a given element to a baseline region. If the threshold value is exceeded, the pulse is classified as a "hit" and that data is collected and an average spectrum is generated from an arithmetic average of "hits". The true metal concentration is determined from the averaged spectrum.

  16. Bicep2 III: Instrumental Systematics

    NASA Astrophysics Data System (ADS)

    Bicep2 Collaboration; Ade, P. A. R.; Aikin, R. W.; Barkats, D.; Benton, S. J.; Bischoff, C. A.; Bock, J. J.; Brevik, J. A.; Buder, I.; Bullock, E.; Dowell, C. D.; Duband, L.; Filippini, J. P.; Fliescher, S.; Golwala, S. R.; Halpern, M.; Hasselfield, M.; Hildebrandt, S. R.; Hilton, G. C.; Irwin, K. D.; Karkare, K. S.; Kaufman, J. P.; Keating, B. G.; Kernasovskiy, S. A.; Kovac, J. M.; Kuo, C. L.; Leitch, E. M.; Lueker, M.; Netterfield, C. B.; Nguyen, H. T.; O'Brient, R.; Ogburn, R. W., IV; Orlando, A.; Pryke, C.; Richter, S.; Schwarz, R.; Sheehy, C. D.; Staniszewski, Z. K.; Sudiwala, R. V.; Teply, G. P.; Tolan, J. E.; Turner, A. D.; Vieregg, A. G.; Wong, C. L.; Yoon, K. W.

    2015-12-01

    In a companion paper, we have reported a >5σ detection of degree scale B-mode polarization at 150 GHz by the Bicep2 experiment. Here we provide a detailed study of potential instrumental systematic contamination to that measurement. We focus extensively on spurious polarization that can potentially arise from beam imperfections. We present a heuristic classification of beam imperfections according to their symmetries and uniformities, and discuss how resulting contamination adds or cancels in maps that combine observations made at multiple orientations of the telescope about its boresight axis. We introduce a technique, which we call “deprojection,” for filtering the leading order beam-induced contamination from time-ordered data, and show that it reduces power in Bicep2's actual and null-test BB spectra consistent with predictions using high signal-to-noise beam shape measurements. We detail the simulation pipeline that we use to directly simulate instrumental systematics and the calibration data used as input to that pipeline. Finally, we present the constraints on BB contamination from individual sources of potential systematics. We find that systematics contribute BB power that is a factor of ˜10× below Bicep2's three-year statistical uncertainty, and negligible compared to the observed BB signal. The contribution to the best-fit tensor/scalar ratio is at a level equivalent to r = (3-6) × 10-3.

  17. The SPIRE Instrument for Herschel

    NASA Astrophysics Data System (ADS)

    Griffin, M. J.; Swinyard, B. M.; Vigroux, L.

    2001-07-01

    SPIRE, the Spectral and Photometric Imaging Receiver, will be a bolometer instrument for ESA's Herschel satellite. Its main scientific goals are deep extragalactic and galactic imaging surveys and spectroscopy of star-forming regions in own and nearby galaxies. The SPIRE detectors are feedhorn-coupled NTD ``spider-web'' bolometers. The instrument comprises a three-band imaging photometer covering the 250-500 micron range, and an imaging Fourier Transform Spectrometer (FTS) covering 200-670 microns. The photometer has a field of view of 4 x 8 arcminutes which is observed simultaneously at 250, 350 and 500 microns, with dichroic beam dividers separating the three spectral bands. Its angular resolution is determined by the telescope diffraction limit, with FWHM beam widths of approximately 17, 24 and 35 arcseconds at 250, 350 and 500 microns, respectively. An internal beam steering mirror can be used for spatial modulation of the telescope beam, and observations can also be made by scanning the telescope without chopping, providing better sensitivity for source confusion-limited deep surveys. The FTS has a field of view of 2.6 arcminutes and an adjustable spectral resolution of 0.04 - 2 cm-1 (λ/Δλ = 20 - 1000 at 250 microns). It employs a dual-beam configuration with novel broad-band intensity beam dividers to provide high efficiency and separated output and input ports.

  18. Focal Plane Instrumentation of VERITAS

    NASA Astrophysics Data System (ADS)

    Nagai, T.; McKay, R.; Sleege, G.; Petry, D.

    VERITAS is a new atmospheric Cherenkov imaging telescope array to detect very high energy gamma rays above 100 GeV. The array is located in southern Arizona, USA, at an altitude of 1270m above see level. The array currently consists of four 12 m telescopes, structurally resembling the Davis-Cotton design of the Whipple 10 m telescope. The VERITAS focal plane instruments are equipped with high-resolution (499 pixels) fast photo-multiplier-tube (PMT) cameras covering a 3.5 degree field of view with 0.148 degree pixel separation. Light concentrators reduce the dead-space between PMTs to 25% and shield the PMTs from ambient light. The PMTs are connected to high-speed pre-amplifiers improving the signal to noise ratio and allow single photoelectron measurements in situ at operating voltage. Current monitor circuits in the focus box provide real-time monitoring of the anode currents for each pixel and ambient conditions of the focus box. A charge injection system installed in the focus box allows daytime testing of the trigger and data acquisition system by injecting pulses of variable amplitude and length into pre-amplifier stage. A detailed description of the VERITAS focal plane instruments will be given in this presentation.

  19. Instrumenting the Intelligence Analysis Process

    SciTech Connect

    Hampson, Ernest; Cowley, Paula J.

    2005-05-02

    The Advanced Research and Development Activity initiated the Novel Intelligence from Massive Data (NIMD) program to develop advanced analytic technologies and methodologies. In order to support this objective, researchers and developers need to understand what analysts do and how they do it. In the past, this knowledge generally was acquired through subjective feedback from analysts. NIMD established the innovative Glass Box Analysis (GBA) Project to instrument a live intelligence mission and unobtrusively capture and objectively study the analysis process. Instrumenting the analysis process requires tailor-made software hooks that grab data from a myriad of disparate application operations and feed into a complex relational database and hierarchical file store to collect, store, retrieve, and distribute analytic data in a manner that maximizes researchers’ understanding. A key to success is determining the correct data to collect and aggregate low-level data into meaningful analytic events. This paper will examine how the GBA team solved some of these challenges, continues to address others, and supports a growing user community in establishing their own GBA environments and/or studying the data generated by GBA analysts working in the Glass Box.

  20. BICEP2 III: Instrumental systematics

    DOE PAGES

    Ade, P. A. R.

    2015-11-23

    In a companion paper, we have reported a >5σ detection of degree scale B-mode polarization at 150 GHz by the Bicep2 experiment. Here we provide a detailed study of potential instrumental systematic contamination to that measurement. We focus extensively on spurious polarization that can potentially arise from beam imperfections. We present a heuristic classification of beam imperfections according to their symmetries and uniformities, and discuss how resulting contamination adds or cancels in maps that combine observations made at multiple orientations of the telescope about its boresight axis. We introduce a technique, which we call "deprojection," for filtering the leading ordermore » beam-induced contamination from time-ordered data, and show that it reduces power in Bicep2's actual and null-test BB spectra consistent with predictions using high signal-to-noise beam shape measurements. We detail the simulation pipeline that we use to directly simulate instrumental systematics and the calibration data used as input to that pipeline. Finally, we present the constraints on BB contamination from individual sources of potential systematics. We find that systematics contribute BB power that is a factor of ~10× below Bicep2's three-year statistical uncertainty, and negligible compared to the observed BB signal. Lastly, the contribution to the best-fit tensor/scalar ratio is at a level equivalent to r = (3–6) × 10–3.« less

  1. PACMAN: PRIMA astrometric instrument software

    NASA Astrophysics Data System (ADS)

    Abuter, Roberto; Sahlmann, Johannes; Pozna, Eszter

    2010-07-01

    The dual feed astrometric instrument software of PRIMA (PACMAN) that is currently being integrated at the VLTI will use two spatially modulated fringe sensor units and a laser metrology system to carry out differential astrometry. Its software and hardware compromises a distributed system involving many real time computers and workstations operating in a synchronized manner. Its architecture has been designed to allow the construction of efficient and flexible calibration and observation procedures. In parallel, a novel scheme of integrating M-code (MATLAB/OCTAVE) with standard VLT (Very Large Telescope) control software applications had to be devised in order to support numerically intensive operations and to have the capacity of adapting to fast varying strategies and algorithms. This paper presents the instrument software, including the current operational sequences for the laboratory calibration and sky calibration. Finally, a detailed description of the algorithms with their implementation, both under M and C code, are shown together with a comparative analysis of their performance and maintainability.

  2. Program Instrumentation and Trace Analysis

    NASA Technical Reports Server (NTRS)

    Havelund, Klaus; Goldberg, Allen; Filman, Robert; Rosu, Grigore; Koga, Dennis (Technical Monitor)

    2002-01-01

    Several attempts have been made recently to apply techniques such as model checking and theorem proving to the analysis of programs. This shall be seen as a current trend to analyze real software systems instead of just their designs. This includes our own effort to develop a model checker for Java, the Java PathFinder 1, one of the very first of its kind in 1998. However, model checking cannot handle very large programs without some kind of abstraction of the program. This paper describes a complementary scalable technique to handle such large programs. Our interest is turned on the observation part of the equation: How much information can be extracted about a program from observing a single execution trace? It is our intention to develop a technology that can be applied automatically and to large full-size applications, with minimal modification to the code. We present a tool, Java PathExplorer (JPaX), for exploring execution traces of Java programs. The tool prioritizes scalability for completeness, and is directed towards detecting errors in programs, not to prove correctness. One core element in JPaX is an instrumentation package that allows to instrument Java byte code files to log various events when executed. The instrumentation is driven by a user provided script that specifies what information to log. Examples of instructions that such a script can contain are: 'report name and arguments of all called methods defined in class C, together with a timestamp'; 'report all updates to all variables'; and 'report all acquisitions and releases of locks'. In more complex instructions one can specify that certain expressions should be evaluated and even that certain code should be executed under various conditions. The instrumentation package can hence be seen as implementing Aspect Oriented Programming for Java in the sense that one can add functionality to a Java program without explicitly changing the code of the original program, but one rather writes an

  3. The HYDICE instrument design and its application to planetary instruments

    NASA Astrophysics Data System (ADS)

    Basedow, R.; Silverglate, P.; Rappoport, W.; Rockwell, R.; Rosenberg, D.; Shu, K.; Whittlesey, R.; Zalewski, E.

    The Hyperspectral Digital Imagery Collection Experiment (HYDICE) instrument represents a significant advance in the state of the art in hyperspectral sensors. It combines a higher signal-to-noise ratio (SNR) and significantly better spatial and spectral resolution and radio metric accuracy than systems flying on aircraft today. The need for 'clean' data, i.e., data free of sampling artifacts and excessive spatial or spectral noise, is a key driver behind the difficult combination of performance requirements laid out for HYDICE. Most of these involve the sensor optics and detector. This paper presents an optimized approach to those requirements, one that comprises push broom scanning, a single, mechanically cooled focal plane, a double-pass prism spectrometer, and an easily fabricated yet wide-field telescope. Central to the approach is a detector array that covers the entire spectrum from 0.4 to 2.5 microns. Among the major benefits conferred by such a design are optical and mechanical simplicity, low polarization sensitivity, and coverage of the entire spectrum without suffering the spectral gaps caused by beam splitters. The overall system minimizes interfaces to the C-141 aircraft on which it will be flown, can be calibrated on the ground and in flight to accuracies better than those required, and is designed for simple, push-button operation. Only unprocessed data are recorded during flight. A ground data processing station provides quick-look, calibration correction, and archiving capabilities, with a throughput better than the requirements. Overall performance of the system is expected to provide the solid database required to evaluate the potential of hyperspectral imagery in a wide variety of applications. HYDICE can be regarded as a test bed for future planetary instruments. The ability to spectrally image a wide field of view over multiple spectral octaves offers obvious advantages and is expected to maximize science return for the required cost and

  4. Geo-conservation: an example of the application of its principles in the sanitation of the polluted Laarder Wasmeren area near Hilversum, het Gooi, The Netherlands.

    NASA Astrophysics Data System (ADS)

    Sevink, Jan; Khodabux, Eric; Landsmeer, Dick; Stoeten, Jan

    2013-04-01

    The Laarder Wasmeren area near Hilversum, a nature reserve under management of the Goois Natuurreservaat with extensive drift sands and several fens, was heavily polluted by heavy metals and toxic organic substances as a result of prolonged discharge of sewage water onto the fens. Already upon the start of its environmental restoration in 2004, it became clear that the area holds important geological phenomena, including LateGlacial paleosols and multiple Holocene drift sands with intercalated paleosols. This discovery induced the Province of Noord-Holland in 2006 to declare het Gooi, of which the Laarder Wasmeren area forms part, a geological monument and thus to set limits for future activities that might lead to disturbance of its superficial geology. Today het Gooi is one of the 17 geological monuments of the province. The basic principle of provincial geo-conservation - minimal disturbance of the superficial geology - was also applied in the further restoration of the LWM area that included its ecological restoration as a nature reserve. This restoration project was supervised by the author and belongs to the major operations of that kind in the Netherlands. Completed in 2010/2011, it resulted in the discovery and conservation of a complex of Holocene drift sands and paleosols that is unique for the Netherlands. The project forms an excellent example of the application of a provincial geo-conservation policy.

  5. Geo-conservation: an example of the application of its principles in the sanitation of the polluted Laarder Wasmeren area near Hilversum, het Gooi, The Netherlands

    NASA Astrophysics Data System (ADS)

    Sevink, J.; Khodabux, E. R.; Landsmeer, D.; Stoeten, G. J.

    2012-04-01

    The Laarder Wasmeren area near Hilversum, a nature reserve under management of the Goois Natuurreservaat with extensive drift sands and several fens, was heavily polluted by heavy metals and toxic organic substances as a result of prolonged discharge of sewage water onto the fens. Already upon the start of its environmental restoration in 2004, it became clear that the area holds important geological phenomena, including LateGlacial paleosols and multiple Holocene drift sands with intercalated paleosols. This discovery induced the Province of Noord-Holland in 2006 to declare het Gooi, of which the Laarder Wasmeren area forms part, a geological monument and thus to set limits for future activities that might lead to disturbance of its superficial geology. Today het Gooi is one of the 17 geological monuments of the province. The basic principle of provincial geo-conservation - minimal disturbance of the superficial geology - was also applied in the further restoration of the LWM area that included its ecological restoration as a nature reserve. This restoration project was supervised by the author and belongs to the major operations of that kind in the Netherlands. Completed in 2010/2011, it resulted in the discovery and conservation of a complex of Holocene drift sands and paleosols that is unique for the Netherlands. The project forms an excellent example of the application of a provincial geo-conservation policy.

  6. Cyanobacterial Cell Lineage Analysis of the Spatiotemporal hetR Expression Profile during Heterocyst Pattern Formation in Anabaena sp. PCC 7120

    PubMed Central

    Kawai, Kentaro; Ehira, Shigeki; Ishihara, Jun-ichi; Aihara, Kazuyuki; Shoji, Shuichi

    2009-01-01

    Diazotrophic heterocyst formation in the filamentous cyanobacterium, Anabaena sp. PCC 7120, is one of the simplest pattern formations known to occur in cell differentiation. Most previous studies on heterocyst patterning were based on statistical analysis using cells collected or observed at different times from a liquid culture, which would mask stochastic fluctuations affecting the process of pattern formation dynamics in a single bacterial filament. In order to analyze the spatiotemporal dynamics of heterocyst formation at the single filament level, here we developed a culture system to monitor simultaneously bacterial development, gene expression, and phycobilisome fluorescence. We also developed micro-liquid chamber arrays to analyze multiple Anabaena filaments at the same time. Cell lineage analyses demonstrated that the initial distributions of hetR::gfp and phycobilisome fluorescence signals at nitrogen step-down were not correlated with the resulting distribution of developed heterocysts. Time-lapse observations also revealed a dynamic hetR expression profile at the single-filament level, including transient upregulation accompanying cell division, which did not always lead to heterocyst development. In addition, some cells differentiated into heterocysts without cell division after nitrogen step-down, suggesting that cell division in the mother cells is not an essential requirement for heterocyst differentiation. PMID:19823574

  7. Evolution of microcomputer-based medical instrumentation.

    PubMed

    Tompkins, Willis J

    2009-01-01

    This paper provides a historical review of the evolution of the technologies that led to modern microcomputer-based medical instrumentation. I review the history of the microprocessor-based system because of the importance of the microprocessor in the design of modern medical instruments. I then give some examples of medical instruments in which the microprocessor has played a key role and in some cases has even empowered us to develop new instruments that were not possible before. I include a discussion of the role of the microprocessor-based personal computer in development of medical instruments.

  8. Instrumentation for detailed bridge-scour measurements

    USGS Publications Warehouse

    Landers, Mark N.; Mueller, David S.; Trent, Roy E.

    1993-01-01

    A portable instrumentation system is being developed to obtain channel bathymetry during floods for detailed bridge-scour measurements. Portable scour measuring systems have four components: sounding instrument, horizontal positioning instrument, deployment mechanisms, and data storage device. The sounding instrument will be a digital fathometer. Horizontal position will be measured using a range-azimuth based hydrographic survey system. The deployment mechanism designed for this system is a remote-controlled boat using a small waterplane area, twin-hull design. An on-board computer and radio will monitor the vessel instrumentation, record measured data, and telemeter data to shore.

  9. Instrumentation at the Anglo-Australian Observatory

    NASA Astrophysics Data System (ADS)

    Barden, Samuel C.

    2004-09-01

    The Anglo-Australian Observatory (AAO) has an instrumentation group for engineering, design, and fabrication that integrates tightly with an energetic group of instrument scientists1 to develop complex astronomical instruments. This instrumentation group puts ideas for innovative technical solutions generated by the instrument scientist group into reality. One demonstration of past achievement is the highly ambitious and successful 2dF instrument that yielded invaluable scientific insight into the cosmological structure of the universe. The more recent successes of the instrumentation group include the OzPoz fiber positioner for the FLAMES facility on the VLT and the award-winning, imaging and multi-object IRIS-2 infrared spectrograph for the AAT. VPH gratings were first put into action in LDSS++ on the AAT and numerous VPH gratings are now in routine use on the 6dF spectrograph for the UKST. Under development are a completely new and unique fiber positioning scheme (Echidna) for use in the FMOS instrument for Subaru; a double-beamed, VPH-based, bench-mounted spectrograph for 2dF; new IR and optical detector controllers; a renovation of the telescope and instrument control systems for the AAT; and a feasibility study for an Echidna-style positioner for the Gemini telescopes. Several other design studies are underway for new instrument technologies using leading edge and innovative concepts in robotics and fibers. The synergy between our scientists and engineers establishes a sound basis for solving the instrumentation challenges facing us.

  10. Infrared Instrument for Detecting Hydrogen Fires

    NASA Technical Reports Server (NTRS)

    Youngquist, Robert; Ihlefeld, Curtis; Immer, Christopher; Oostdyk, Rebecca; Cox, Robert; Taylor, John

    2006-01-01

    The figure shows an instrument incorporating an infrared camera for detecting small hydrogen fires. The instrument has been developed as an improved replacement for prior infrared and ultraviolet instruments used to detect hydrogen fires. The need for this or any such instrument arises because hydrogen fires (e.g., those associated with leaks from tanks, valves, and ducts) pose a great danger, yet they emit so little visible light that they are mostly undetectable by the unaided human eye. The main performance advantage offered by the present instrument over prior hydrogen-fire-detecting instruments lies in its greater ability to avoid false alarms by discriminating against reflected infrared light, including that originating in (1) the Sun, (2) welding torches, and (3) deliberately ignited hydrogen flames (e.g., ullage-burn-off flames) that are nearby but outside the field of view intended to be monitored by the instrument. Like prior such instruments, this instrument is based mostly on the principle of detecting infrared emission above a threshold level. However, in addition, this instrument utilizes information on the spatial distribution of infrared light from a source that it detects. Because the combination of spatial and threshold information about a flame tends to constitute a unique signature that differs from that of reflected infrared light originating in a source not in the field of view, the incidence of false alarms is reduced substantially below that of related prior threshold- based instruments.

  11. Overview of coal conversion process instrumentation

    SciTech Connect

    Liptak, B. G.; Leiter, C. P.

    1980-05-01

    A review of standard instrumentation used in the processing industries is given, and the applicability of this instrumentation to measurements in mixed phase media and hostile environments such as those encountered in coal conversion processes is considered. The major projects in coal conversion sponsored by the US Department of Energy are briefly reviewed with schematics to pinpoint areas where the standard instrumentation is inadequate or altogether lacking. The next report in this series will provide detailed requirements on the instruments needed for these processes, will review new instruments which have recently become commercially available but are not yet considered standard instrumentation, and report on the status of new instruments which are being developed and, in some cases, undergoing tests in coal conversion plants.

  12. Preliminary analysis of a flexible instrument mount for large instruments on the Space Shuttle

    NASA Technical Reports Server (NTRS)

    1978-01-01

    A flexible instrument mount for large instruments on the space shuttle is analyzed. Concepts for pointing instruments while in orbit, with weights up to 2000 Kg and dimensions of 2 to 3 m were identified and analyzed. A mechanical concept was selected that can accommodate a set class of scientific instruments such as the LAMAR X-ray experiment with 24 LAMAR telescopes.

  13. RECENT DEVELOPMENTS IN HYDROLOGIC INSTRUMENTATION.

    USGS Publications Warehouse

    Latkovich, Vito J.

    1985-01-01

    The availability of space-age materials and implementation of state-of-the-art electronics is making possible the recent developments of hydrologic instrumentation. Material developments include: Synthetic-fiber sounding and tag lines; fiberglass wading rod; polymer (plastic) sheaves, pulleys and sampler components; and polymer (plastic) bucket wheels for current meters. These materials are very cost effective and efficient. Electromechanical and electronic developments and applications include: adaptable data acquisition system; downhole sampler for hazardous substances; current-meter digitizer; hydraulic power/drive system for discharge measurements and water-quality sampling; non-contact water-level sensors; minimum data recorder; acoustic velocity meters, and automated current meter discharge-measurement system.

  14. Forward instrumentation for ILC detectors

    NASA Astrophysics Data System (ADS)

    Abramowicz, H.; Abusleme, A.; Afanaciev, K.; Aguilar, J.; Ambalathankandy, P.; Bambade, P.; Bergholz, M.; Bozovic-Jelisavcic, I.; Castro, E.; Chelkov, G.; Coca, C.; Daniluk, W.; Dragone, A.; Dumitru, L.; Elsener, K.; Emeliantchik, I.; Fiutowski, T.; Gostkin, M.; Grah, C.; Grzelak, G.; Haller, G.; Henschel, H.; Ignatenko, A.; Idzik, M.; Ito, K.; Jovin, T.; Kielar, E.; Kotula, J.; Krumstein, Z.; Kulis, S.; Lange, W.; Lohmann, W.; Levy, A.; Moszczynski, A.; Nauenberg, U.; Novgorodova, O.; Ohlerich, M.; Orlandea, M.; Oleinik, G.; Oliwa, K.; Olshevski, A.; Pandurovic, M.; Pawlik, B.; Przyborowski, D.; Sato, Y.; Sadeh, I.; Sailer, A.; Schmidt, R.; Schumm, B.; Schuwalow, S.; Smiljanic, I.; Swientek, K.; Takubo, Y.; Teodorescu, E.; Wierba, W.; Yamamoto, H.; Zawiejski, L.; Zhang, J.

    2010-12-01

    Two special calorimeters are foreseen for the instrumentation of the very forward region of the ILC detector, a luminometer designed to measure the rate of low angle Bhabha scattering events with a precision better than 10-3 and a low polar angle calorimeter, adjacent to the beam-pipe. The latter will be hit by a large amount of beamstrahlung remnants. The amount and shape of these depositions will allow a fast luminosity estimate and the determination of beam parameters. The sensors of this calorimeter must be radiation hard. Both devices will improve the hermeticity of the detector in the search for new particles. Finely segmented and very compact calorimeters will match the requirements. Due to the high occupancy fast front-end electronics is needed. The design of the calorimeters developed and optimised with Monte Carlo simulations is presented. Sensors and readout electronics ASICs have been designed and prototypes are available. Results on the performance of these major components are summarised.

  15. Images from Phoenix's MECA Instruments

    NASA Technical Reports Server (NTRS)

    2008-01-01

    The image on the upper left is from NASA's Phoenix Mars Lander's Optical Microscope after a sample informally called 'Sorceress' was delivered to its silicon substrate on the 38th Martian day, or sol, of the mission (July 2, 2008).

    A 3D representation of the same sample is on the right, as seen by Phoenix's Atomic Force Microscope. This is 100 times greater magnification than the view from the Optical Microscope, and the most highly magnified image ever seen from another world.

    The Optical Microscope and the Atomic Force Microscope are part of Phoenix's Microscopy, Electrochemistry and Conductivity Analyzer instrument.

    The Atomic Force Microscope was developed by a Swiss-led consortium in collaboration with Imperial College London.

    The Phoenix Mission is led by the University of Arizona, Tucson, on behalf of NASA. Project management of the mission is by NASA's Jet Propulsion Laboratory, Pasadena, Calif. Spacecraft development is by Lockheed Martin Space Systems, Denver.

  16. Application of Fiber Optic Instrumentation

    NASA Technical Reports Server (NTRS)

    Richards, William Lance; Parker, Allen R., Jr.; Ko, William L.; Piazza, Anthony; Chan, Patrick

    2012-01-01

    Fiber optic sensing technology has emerged in recent years offering tremendous advantages over conventional aircraft instrumentation systems. The advantages of fiber optic sensors over their conventional counterparts are well established; they are lighter, smaller, and can provide enormous numbers of measurements at a fraction of the total sensor weight. After a brief overview of conventional and fiber-optic sensing technology, this paper presents an overview of the research that has been conducted at NASA Dryden Flight Research Center in recent years to advance this promising new technology. Research and development areas include system and algorithm development, sensor characterization and attachment, and real-time experimentally-derived parameter monitoring for ground- and flight-based applications. The vision of fiber optic smart structure technology is presented and its potential benefits to aerospace vehicles throughout the lifecycle, from preliminary design to final retirement, are presented.

  17. SOFIA First Generation Science Instruments

    NASA Technical Reports Server (NTRS)

    Erickson, Edwin F.; Meyer, Allan W.

    2003-01-01

    SOFIA will provide 0.3- 1600 pm wavelength coverage, excellent FIR/submm angular resolution, a variety of focal plane instruments, and access to them throughout a 20-year lifetime. These attributes assure SOFIA a vital role in future observations of the interstellar medium, and in numerous other studies. SOFIA is a joint program of NASA in the U.S. and DLR in Germany. Observing time will be arranged by annual peer review of proposals, with roughly 80 percent of the time granted by the U.S. and 20 percent of the time granted by Germany. International proposals may be submitted to either time allocation committee. SOFIA is expected to begin science flights in 2005.

  18. Recent Developments in PET Instrumentation

    PubMed Central

    Peng, Hao; Levin, Craig S.

    2013-01-01

    Positron emission tomography (PET) is used in the clinic and in vivo small animal research to study molecular processes associated with diseases such as cancer, heart disease, and neurological disorders, and to guide the discovery and development of new treatments. This paper reviews current challenges of advancing PET technology and some of newly developed PET detectors and systems. The paper focuses on four aspects of PET instrumentation: high photon detection sensitivity; improved spatial resolution; depth-of-interaction (DOI) resolution and time-of-flight (TOF). Improved system geometry, novel non-scintillator based detectors, and tapered scintillation crystal arrays are able to enhance the photon detection sensitivity of a PET system. Several challenges for achieving high resolution with standard scintillator-based PET detectors are discussed. Novel detectors with 3-D positioning capability have great potential to be deployed in PET for achieving spatial resolution better than 1 mm, such as cadmium-zinc-telluride (CZT) and position-sensitive avalanche photodiodes (PSAPDs). DOI capability enables a PET system to mitigate parallax error and achieve uniform spatial resolution across the field-of-view (FOV). Six common DOI designs, as well as advantages and limitations of each design, are discussed. The availability of fast scintillation crystals such as LaBr3, and the silicon photomultiplier (SiPM) greatly advances TOF-PET development. Recent instrumentation and initial results of clinical trials are briefly presented. If successful, these technology advances, together with new probe molecules, will substantially enhance the molecular sensitivity of PET and thus increase its role in preclinical and clinical research as well as evaluating and managing disease in the clinic. PMID:20497121

  19. MC and A instrumentation catalog

    SciTech Connect

    Neymotin, L.; Sviridova, V.

    1998-06-01

    In 1981 and 1985, two editions of a catalog of non-destructive nuclear measurement instrumentation, and material control and surveillance equipment, were published by Brookhaven National Laboratory (BNL). The last edition of the catalog included one hundred and twenty-five entries covering a wide range of devices developed in the US and abroad. More than ten years have elapsed since the publication of the more recent Catalog. Devices described in it have undergone significant modifications, and new devices have been developed. Therefore, in order to assist specialists in the field of Material Control and Accounting (MC and A), a new catalog has been created. Work on this instrumentation catalog started in 1997 as a cooperative effort of Brookhaven National Laboratory (BNL), operated by Brookhaven Science Associates under contract to the US Department of Energy, and the All-Russian Research Institute of Automatics (VNIIA), subordinate institute of the Atomic Energy Ministry of the Russian Federation, within the collaborative US-Russia Material Protection, Control, and Accounting (MPC and A) Program. Most of the equipment included in the Catalog are non-destructive assay (NDA) measurement devices employed for purposes of accounting, confirmation, and verification of nuclear materials. Other devices also included in the Catalog are employed in the detection and deterrence of unauthorized access to or removal of nuclear materials (material control: containment and surveillance). Equipment found in the Catalog comprises either: (1) complete devices or systems that can be used for MC and A applications; or (2) parts or components of complete systems, such as multi-channel analyzers, detectors, neutron generators, and software. All devices are categorized by their status of development--from prototype to serial production.

  20. [Drug advertising as communication between the pharmaceutical industry and the physician: advertisements for psychotropic drugs in the Dutch medical journal, Nederlands Tijdschrift voor Geneeskunde, 1900-1940].

    PubMed

    van der Hoogte, Arjo Roersch; Pieters, Toine

    2010-01-01

    In this article we explore the historical development of drug advertisements for psychotropic drugs in the leading Dutch medical journal from 1900 to 1940. The advertisements for hypnotics and sedatives, in The Nederlands Tijdschrift voor Geneeskunde (Dutch medical journal) reflected the changes in the vocabulary and image promoted by the pharmaceutical companies. In the first two decades, the advertisements were sober and to the point, and included the trademark, company name, molecular formula and therapeutic properties of the medication. The emphasis was on creating a scientific image of reliable symptom control for the therapeutic drug. In doing so, the ethical drug companies tried (successfully) to distinguish themselves from the producers of patent medicines. Once scientific credibility was established, the form and content of the advertisements changed significantly. In the late 1920s and 1930s drug companies embraced modern advertising techniques, developing a figurative language to address the changing beliefs and practices of Dutch physicians. Instead of promoting therapeutic drugs as safe and scientific, the emphasis was on their effectiveness in comparison to similar drugs. In the process, scientific information was reduced to an indispensable standardized minimum, whereby therapeutic drugs were advertised according to the latest pharmacological taxonomy rather than molecular formulas. The image-making of 'ethical marketing' began during the interwar years when marketers applied modern advertising techniques and infotainment strategies. The scanty black and white informational bulletins transitioned into colourful advertisements. The pharmaceutical companies employed the same medical language as used by physicians, so that one word or image in an advertisement would suffice for the physician to recognize a drug and its therapeutic properties. These developments show the changing relationship between the modern ethical pharmaceutical industry and Dutch

  1. [Drug advertising as communication between the pharmaceutical industry and the physician: advertisements for psychotropic drugs in the Dutch medical journal, Nederlands Tijdschrift voor Geneeskunde, 1900-1940].

    PubMed

    van der Hoogte, Arjo Roersch; Pieters, Toine

    2010-01-01

    In this article we explore the historical development of drug advertisements for psychotropic drugs in the leading Dutch medical journal from 1900 to 1940. The advertisements for hypnotics and sedatives, in The Nederlands Tijdschrift voor Geneeskunde (Dutch medical journal) reflected the changes in the vocabulary and image promoted by the pharmaceutical companies. In the first two decades, the advertisements were sober and to the point, and included the trademark, company name, molecular formula and therapeutic properties of the medication. The emphasis was on creating a scientific image of reliable symptom control for the therapeutic drug. In doing so, the ethical drug companies tried (successfully) to distinguish themselves from the producers of patent medicines. Once scientific credibility was established, the form and content of the advertisements changed significantly. In the late 1920s and 1930s drug companies embraced modern advertising techniques, developing a figurative language to address the changing beliefs and practices of Dutch physicians. Instead of promoting therapeutic drugs as safe and scientific, the emphasis was on their effectiveness in comparison to similar drugs. In the process, scientific information was reduced to an indispensable standardized minimum, whereby therapeutic drugs were advertised according to the latest pharmacological taxonomy rather than molecular formulas. The image-making of 'ethical marketing' began during the interwar years when marketers applied modern advertising techniques and infotainment strategies. The scanty black and white informational bulletins transitioned into colourful advertisements. The pharmaceutical companies employed the same medical language as used by physicians, so that one word or image in an advertisement would suffice for the physician to recognize a drug and its therapeutic properties. These developments show the changing relationship between the modern ethical pharmaceutical industry and Dutch

  2. HET2 Overview

    NASA Technical Reports Server (NTRS)

    Fong, Terrence W.; Bualat, Maria Gabriele; Diftler, Myron A.

    2015-01-01

    2015 mid-year review charts of the Human Exploration Telerobotics 2 project that describe the Astrobee free-flying robot and the Robonaut 2 humanoid robot. A planned replacement for Synchronized Position Hold, Engage, Reorient, Experimental Satellite (SPHERES), which is currently in use in the International Space Station (ISS).

  3. THOR Electric Field Instrument - EFI

    NASA Astrophysics Data System (ADS)

    Khotyaintsev, Yuri; Bale, Stuart D.; Bonnell, John W.; Lindqvist, Per-Arne; Phal, Yamuna; Rothkaehl, Hanna; Soucek, Jan; Vaivads, Andris; Åhlen, Lennart

    2016-04-01

    Turbulence Heating ObserveR (THOR) is the first mission ever flown in space dedicated to plasma turbulence. The Electric Field Instrument (EFI) will measure the vector electric field from 0 to 200 kHz. EFI consists of two sets of sensors: Spin-plane Double Probes (EFI-SDP) providing high sensitivity DC electric field in the spacecraft spin plane (2D), and the High-Frequency Antenna (EFI-HFA) providing 3D electric field at frequencies above ~1 kHz. EFI-SDP consists of 4 biased spherical probes extended on 50 m long wire booms, 90 degrees apart in the spin plane, giving a 100 m baseline for each of the two spin-plane electric field components. EFI-HFA consists of 6 x 1.25 m long monopoles, forming 3 dipolar antennas crossed at 90 degrees to each other. In addition to the sensors, EFI contains HFA and SDP pre-amplifiers, as well as bias electronics boards (BEBs) hosted in the man electronics box of the Field and Wave processor (FWP). As THOR spacecraft has a sun-pointing spin axis, EFI-SDP measures the electric field in the plane approximately orthogonal to the sun using long wire booms. The sun-pointing attitude greatly reduces errors due to wake effects and asymmetric photoelectron clouds, enabling the highly accurate in comparison to earlier missions ±0.1 mV/m near-DC electric field measurements. Interferometry using the electric field probes can be used to infer wavelengths and scale sizes at the smallest scales in the plasma. EFI also measures the floating potential of the satellite, which can be used to estimate the plasma density at very high time resolution (up to a few hundred Hz). The sun-pointing attitude greatly reduces changes in the illuminated area, and hence the associated spin-dependent errors. In combination with densities derived from the observed plasma frequency emission line, EFI monitors the plasma density from DC to a few hundred Hz. EFI measurements characterize electric field and density variations associated with kinetic scale plasma

  4. Demonstration of an instrumented patch

    NASA Astrophysics Data System (ADS)

    Martinez, M.; Renaud, G.; Backman, D.; Genest, M.; Delannoy, M.

    2007-04-01

    The primary objective of this study was to demonstrate the effectiveness of various strain measurement techniques at detecting the disbonding of a composite repair patch and then using this information to validate a new capacitance based disbond detection technique. The instrumented repair patch was parametrically designed with the help of Finite Element Analysis (FEA) software to have a stress concentration at its tip. This stress concentration was designed to produce a disbond during fatigue testing, without the need for the introduction of any foreign material to create an artificial disbond condition. The aluminum substrate was grit blasted and the instrumented patch was bonded using FM ®73 adhesive, and was cured following the recommendations of the manufacturer. The geometric characteristics of the patch followed standard repair guidelines for such variables as material selection, taper angles and loading conditions, with the exception of the area designed for premature disbond. All test specimens were inspected using non-destructive testing technique (ultrasound pulse echo) to guarantee that no disbonding had occurred during curing of the specimen. The specimens were placed under fatigue loading to induce a disbond condition between the aluminum substrate and the patch. The specimens were cyclically loaded and strain gauges bonded to strategic locations on the aluminum and composite patch surface to be able to measure changes in surface strains as the disbond progressed. A Digital Image Correlation (DIC) system was also used to measure full field strains over the gauge length of the coupon. The DIC results were compared with the strain gauge data and were used to provide a qualitative measure of the load transfer in the bonded specimen, which clearly demonstrated the change in surface strain that occurred as the composite patch disbonded from the aluminum substrate. Thermoelastic Stress Analysis (TSA) was also used to measure surface strains on the

  5. Attention is necessary for subliminal instrumental conditioning.

    PubMed

    Mastropasqua, Tommaso; Turatto, Massimo

    2015-01-01

    The capacity of humans and other animals to provide appropriate responses to stimuli anticipating motivationally significant events is exemplified by instrumental conditioning. Interestingly, in humans instrumental conditioning can occur also for subliminal outcome-predicting stimuli. However, it remains unclear whether attention is necessary for subliminal instrumental conditioning to take place. In two experiments, human participants had to learn to collect rewards (monetary gains) while avoiding punishments (monetary losses), on the basis of subliminal outcome-predicting cues. We found that instrumental conditioning can proceed subconsciously only if spatial attention is aligned with the subliminal cue. Conversely, if spatial attention is briefly diverted from the subliminal cue, then instrumental conditioning is blocked. In humans, attention but not awareness is therefore mandatory for instrumental conditioning, thus revealing a dissociation between awareness and attention in the control of motivated behavior. PMID:26257144

  6. [Use of titanium alloys for medical instruments].

    PubMed

    Feofilov, R N; Chirkov, V K; Levin, M V

    1977-01-01

    On the ground of an analysis into properties of titanium and its alloys the fields of their possible utilization for making various medical instruments are proposed. Because of their insufficient hardness and wear-resistance the titanium alloys cannot be recommended for making medical instruments with thin cutting edges. For the reasons of their insufficient strength, low wear-resistance and substandard modulus of elasticity, it is inexpedient to use titanium alloys in making many types of clamping medical instruments. Nor is it advisable to employ titanium alloys in handles of the instruments, for this may lead to a contact corrosion of their working parts. The use of titanium alloys is recommended for making bone-joining members, retracting medical instruments, of the spatula and speculum types, some kinds of non-magnetic pincers and ultrasonic medical instruments.

  7. Attention is necessary for subliminal instrumental conditioning

    PubMed Central

    Mastropasqua, Tommaso; Turatto, Massimo

    2015-01-01

    The capacity of humans and other animals to provide appropriate responses to stimuli anticipating motivationally significant events is exemplified by instrumental conditioning. Interestingly, in humans instrumental conditioning can occur also for subliminal outcome-predicting stimuli. However, it remains unclear whether attention is necessary for subliminal instrumental conditioning to take place. In two experiments, human participants had to learn to collect rewards (monetary gains) while avoiding punishments (monetary losses), on the basis of subliminal outcome-predicting cues. We found that instrumental conditioning can proceed subconsciously only if spatial attention is aligned with the subliminal cue. Conversely, if spatial attention is briefly diverted from the subliminal cue, then instrumental conditioning is blocked. In humans, attention but not awareness is therefore mandatory for instrumental conditioning, thus revealing a dissociation between awareness and attention in the control of motivated behavior. PMID:26257144

  8. Operation and performance of the OSSE instrument

    NASA Astrophysics Data System (ADS)

    Cameron, R. A.; Kurfess, J. D.; Johnson, W. N.; Kinzer, R. L.; Kroeger, R. A.; Leising, M. D.; Murphy, R. J.; Share, G. H.; Strickman, M. S.; Grove, J. E.

    1992-02-01

    The Oriented Scintillation Spectrometer Experiment (OSSE) on the Arthur Holly Compton Gamma Ray Observatory is described. An overview of the operation and control of the instrument is given, together with a discussion of typical observing strategies used with OSSE and basic data types produced by the instrument. Some performance measures for the instrument are presented that were obtained from pre-launch and in-flight data. These include observing statistics, continuum and line sensitivity, and detector effective area and gain stability.

  9. Status of the JWST Science Instrument Payload

    NASA Technical Reports Server (NTRS)

    Greenhouse, Matt

    2016-01-01

    The James Webb Space Telescope (JWST) Integrated Science Instrument Module (ISIM) system consists of five sensors (4 science): Mid-Infrared Instrument (MIRI), Near Infrared Imager and Slitless Spectrograph (NIRISS), Fine Guidance Sensor (FGS), Near InfraRed Camera (NIRCam), Near InfraRed Spectrograph (NIRSpec); and nine instrument support systems: Optical metering structure system, Electrical Harness System; Harness Radiator System, ISIM Electronics Compartment, ISIM Remote Services Unit, Cryogenic Thermal Control System, Command and Data Handling System, Flight Software System, Operations Scripts System.

  10. Recent Topics in Instrumentation and Measurement

    NASA Astrophysics Data System (ADS)

    Tanabe, Kazuo; Fukuchi, Tetsuo; Arakawa, Satoru; Sayama, Shuji

    Instrumentation and measurement play a vital role in research and development in the science and engineering fields. Recently, the goals of instrumentation and measurement have expanded to meet not only the industrial and science requirements but also the needs in all fields of social life, such as medicine and welfare, the environment, and disaster and security. In this article, recent technical topics in the instrumentation and measurement field are reported.

  11. Increasing Laser Stability with Improved Electronic Instruments

    NASA Astrophysics Data System (ADS)

    Troxel, Daylin; Bennett, Aaron; Erickson, Christopher J.; Jones, Tyler; Durfee, Dallin S.

    2010-03-01

    We present several electronic instruments developed to implement an ultra-stable laser lock. These instruments include a high speed, low noise homodyne photo-detector; an ultrahigh stability, low noise current driver with high modulation bandwidth and digital control; a high-speed, low noise PID controller; a low-noise piezo driver; and a laser diode temperature controller. We will present the theory of operation for these instruments, design and construction techniques, and essential characteristics for each device.

  12. Comet coma sample return instrument

    NASA Technical Reports Server (NTRS)

    Albee, A. L.; Brownlee, Don E.; Burnett, Donald S.; Tsou, Peter; Uesugi, K. T.

    1994-01-01

    The sample collection technology and instrument concept for the Sample of Comet Coma Earth Return Mission (SOCCER) are described. The scientific goals of this Flyby Sample Return are to return to coma dust and volatile samples from a known comet source, which will permit accurate elemental and isotopic measurements for thousands of individual solid particles and volatiles, detailed analysis of the dust structure, morphology, and mineralogy of the intact samples, and identification of the biogenic elements or compounds in the solid and volatile samples. Having these intact samples, morphologic, petrographic, and phase structural features can be determined. Information on dust particle size, shape, and density can be ascertained by analyzing penetration holes and tracks in the capture medium. Time and spatial data of dust capture will provide understanding of the flux dynamics of the coma and the jets. Additional information will include the identification of cosmic ray tracks in the cometary grains, which can provide a particle's process history and perhaps even the age of the comet. The measurements will be made with the same equipment used for studying micrometeorites for decades past; hence, the results can be directly compared without extrapolation or modification. The data will provide a powerful and direct technique for comparing the cometary samples with all known types of meteorites and interplanetary dust. This sample collection system will provide the first sample return from a specifically identified primitive body and will allow, for the first time, a direct method of matching meteoritic materials captured on Earth with known parent bodies.

  13. LISA Pathfinder Instrument Data Analysis

    NASA Technical Reports Server (NTRS)

    Guzman, Felipe

    2010-01-01

    LISA Pathfinder (LPF) is an ESA-launched demonstration mission of key technologies required for the joint NASA-ESA gravitational wave observatory in space, LISA. As part of the LPF interferometry investigations, analytic models of noise sources and corresponding noise subtraction techniques have been developed to correct for effects like the coupling of test mass jitter into displacement readout, and fluctuations of the laser frequency or optical pathlength difference. Ground testing of pre-flight hardware of the Optical Metrology subsystem is currently ongoing at the Albert Einstein Institute Hannover. In collaboration with NASA Goddard Space Flight Center, the LPF mission data analysis tool LTPDA is being used to analyze the data product of these tests. Furthermore, the noise subtraction techniques and in-flight experiment runs for noise characterization are being defined as part of the mission experiment master plan. We will present the data analysis outcome of preflight hardware ground tests and possible noise subtraction strategies for in-flight instrument operations.

  14. Surgical Instrument Restraint in Weightlessness

    NASA Technical Reports Server (NTRS)

    Campbell, Mark R.; Dawson, David L.; Melton, Shannon; Hooker, Dona; Cantu, Hilda

    2000-01-01

    Performing a surgical procedure during spaceflight will become more likely with longer duration missions in the near future. Minimal surgical capability has been present on previous missions as the definitive medical care time was short and the likelihood of surgical events too low to justify surgical hardware availability. Early demonstrations of surgical procedures in the weightlessness of parabolic flight indicated the need for careful logistical planning and restraint of surgical hardware. The consideration of human ergonomics also has more impact in weightlessness than in the conventionall-g environment. Three methods of surgical instrument restraint - a Minor Surgical Kit (MSK), a Surgical Restraint Scrub Suit (SRSS), and a Surgical Tray (ST) were evaluated in parabolic flight surgical procedures. The Minor Surgical Kit was easily stored, easily deployed, and demonstrated the best ability to facilitate a surgical procedure in weightlessness. Important factors in this surgical restraint system include excellent organization of supplies, ability to maintain sterility, accessibility while providing secure restraint, ability to dispose of sharp items and biological trash, and ergonomical efficiency.

  15. Bubble Measuring Instrument and Method

    NASA Technical Reports Server (NTRS)

    Kline-Schoder, Robert (Inventor); Magari, Patrick J. (Inventor)

    2002-01-01

    Method and apparatus are provided for a non-invasive bubble measuring instrument operable for detecting, distinguishing, and counting gaseous embolisms such as bubbles over a selectable range of bubble sizes of interest. A selected measurement volume in which bubbles may be detected is insonified by two distinct frequencies from a pump transducer and an image transducer. respectively. The image transducer frequency is much higher than the pump transducer frequency. The relatively low-frequency pump signal is used to excite bubbles to resonate at a frequency related to their diameter. The image transducer is operated in a pulse-echo mode at a controllable repetition rate that transmits bursts of high-frequency ultrasonic signal to the measurement volume in which bubbles may be detected and then receives the echo. From the echo or received signal, a beat signal related to the repetition rate may be extracted and used to indicate the presence or absence of a resonant bubble. In a preferred embodiment, software control maintains the beat signal at a preselected frequency while varying the pump transducer frequency to excite bubbles of different diameters to resonate depending on the range of bubble diameters selected for investigation.

  16. Bubble measuring instrument and method

    NASA Technical Reports Server (NTRS)

    Kline-Schoder, Robert (Inventor); Magari, Patrick J. (Inventor)

    2003-01-01

    Method and apparatus are provided for a non-invasive bubble measuring instrument operable for detecting, distinguishing, and counting gaseous embolisms such as bubbles over a selectable range of bubble sizes of interest. A selected measurement volume in which bubbles may be detected is insonified by two distinct frequencies from a pump transducer and an image transducer, respectively. The image transducer frequency is much higher than the pump transducer frequency. The relatively low-frequency pump signal is used to excite bubbles to resonate at a frequency related to their diameter. The image transducer is operated in a pulse-echo mode at a controllable repetition rate that transmits bursts of high-frequency ultrasonic signal to the measurement volume in which bubbles may be detected and then receives the echo. From the echo or received signal, a beat signal related to the repetition rate may be extracted and used to indicate the presence or absence of a resonant bubble. In a preferred embodiment, software control maintains the beat signal at a preselected frequency while varying the pump transducer frequency to excite bubbles of different diameters to resonate depending on the range of bubble diameters selected for investigation.

  17. Nuclear medicine instrumentation. Historic perspective.

    PubMed

    Croll, M N

    1994-01-01

    Recording the chronology of nuclear medicine instrumentation poses some difficult decisions as does the determination of the "father" of nuclear medicine?. Historians can agree on well-defined dates and events, but many of them are subjective and reside in the memories of those of us who were fortunate to experience the formative years of our field. We all search for the historical truth. The highlights of this story may begin with John Lawrence and phosphorus-32 therapy at Berkeley and continue with Enrico Fermi's sustained nuclear reaction, which lead to the Manhattan Project, then the Atomic Energy Commission, and finally, Sam Seidlin's treatment of thyroid metastases with iodine-131. The rectilinear scanner came to us from Benedict Cassen and was followed by Hal O. Anger and his gamma scintillation camera, one of the most pivotal developments in the field. A plethora of cameras followed: Merrill Benders's digital autofluroscope, Dave Kuhl's efforts for tomographic imaging, and then on to single photon emission computed tomography. Finally, we come back to Hal O. Anger, who suggested and worked with the idea of a positron camera, with positron emission tomography becoming commercially available in 1985. Ours is a variegated history, and I hope that this account speaks the historical truth.

  18. Biomagnetic Measurements Using SQUID Instrumentation

    NASA Astrophysics Data System (ADS)

    Rassi, D.; Zhuravlev, Y.

    2000-09-01

    Biomagnetic measurements involve the detection of the magnetic fields generated by physiological activity in living organisms. Because magnetic fields are sensed remotely, no physical contact with the subject is required, making the technique totally non-invasive Furthermore, only the magnetic fields originating within the body are measured. No external field is applied and it can therefore be confidently stated that the technique is completely safe. These characteristics make biomagnetometry an ideal tool for the investigation of physiological processes. The only magnetic field detector capable of measuring these extremely weak biomagnetic signals is the Superconducting Quantum Interference Device (SQUID). In the last thirty years SQUID-based ultrasensitive magnetometers have been widely used in the investigation of physiologically produced magnetic fields for diagnostic purposes. Owing to the numerous sources of noise and interference typical of an urban environment, it has until recently been considered almost impossible to operate a SQUID magnetometer in such a location without magnetic shielding. We have overcome these technical problems and have successfully used our specially developed unshielded SQUID systems in laboratory and hospital environments. This instrumentation is suitable for recording the biomagnetic fields in adults, neonates and fetuses, and has been applied in a number of clinical studies including fetal magnetocardiography.

  19. The JEM-EUSO instrument

    NASA Astrophysics Data System (ADS)

    Adams, J. H.; Ahmad, S.; Albert, J.-N.; Allard, D.; Anchordoqui, L.; Andreev, V.; Anzalone, A.; Arai, Y.; Asano, K.; Ave Pernas, M.; Baragatti, P.; Barrillon, P.; Batsch, T.; Bayer, J.; Bechini, R.; Belenguer, T.; Bellotti, R.; Belov, K.; Berlind, A. A.; Bertaina, M.; Biermann, P. L.; Biktemerova, S.; Blaksley, C.; Blanc, N.; Błȩcki, J.; Blin-Bondil, S.; Blümer, J.; Bobik, P.; Bogomilov, M.; Bonamente, M.; Briggs, M. S.; Briz, S.; Bruno, A.; Cafagna, F.; Campana, D.; Capdevielle, J.-N.; Caruso, R.; Casolino, M.; Cassardo, C.; Castellinic, G.; Catalano, C.; Catalano, G.; Cellino, A.; Chikawa, M.; Christl, M. J.; Cline, D.; Connaughton, V.; Conti, L.; Cordero, G.; Crawford, H. J.; Cremonini, R.; Csorna, S.; Dagoret-Campagne, S.; de Castro, A. J.; De Donato, C.; de la Taille, C.; De Santis, C.; del Peral, L.; Dell'Oro, A.; De Simone, N.; Di Martino, M.; Distratis, G.; Dulucq, F.; Dupieux, M.; Ebersoldt, A.; Ebisuzaki, T.; Engel, R.; Falk, S.; Fang, K.; Fenu, F.; Fernández-Gómez, I.; Ferrarese, S.; Finco, D.; Flamini, M.; Fornaro, C.; Franceschi, A.; Fujimoto, J.; Fukushima, M.; Galeotti, P.; Garipov, G.; Geary, J.; Gelmini, G.; Giraudo, G.; Gonchar, M.; González Alvarado, C.; Gorodetzky, P.; Guarino, F.; Guzmán, A.; Hachisu, Y.; Harlov, B.; Haungs, A.; Hernández Carretero, J.; Higashide, K.; Ikeda, D.; Ikeda, H.; Inoue, N.; Inoue, S.; Insolia, A.; Isgrò, F.; Itow, Y.; Joven, E.; Judd, E. G.; Jung, A.; Kajino, F.; Kajino, T.; Kaneko, I.; Karadzhov, Y.; Karczmarczyk, J.; Karus, M.; Katahira, K.; Kawai, K.; Kawasaki, Y.; Keilhauer, B.; Khrenov, B. A.; Kim, J.-S.; Kim, S.-W.; Kim, S.-W.; Kleifges, M.; Klimov, P. A.; Kolev, D.; Kreykenbohm, I.; Kudela, K.; Kurihara, Y.; Kusenko, A.; Kuznetsov, E.; Lacombe, M.; Lachaud, C.; Lee, J.; Licandro, J.; Lim, H.; López, F.; Maccarone, M. C.; Mannheim, K.; Maravilla, D.; Marcelli, L.; Marini, A.; Martinez, O.; Masciantonio, G.; Mase, K.; Matev, R.; Medina-Tanco, G.; Mernik, T.; Miyamoto, H.; Miyazaki, Y.; Mizumoto, Y.; Modestino, G.; Monaco, A.; Monnier-Ragaigne, D.; Morales de los Ríos, J. A.; Moretto, C.; Morozenko, V. S.; Mot, B.; Murakami, T.; Murakami, M. Nagano; Nagata, M.; Nagataki, S.; Nakamura, T.; Napolitano, T.; Naumov, D.; Nava, R.; Neronov, A.; Nomoto, K.; Nonaka, T.; Ogawa, T.; Ogio, S.; Ohmori, H.; Olinto, A. V.; Orleański, P.; Osteria, G.; Panasyuk, M. I.; Parizot, E.; Park, I. H.; Park, H. W.; Pastircak, B.; Patzak, T.; Paul, T.; Pennypacker, C.; Perez Cano, S.; Peter, T.; Picozza, P.; Pierog, T.; Piotrowski, L. W.; Piraino, S.; Plebaniak, Z.; Pollini, A.; Prat, P.; Prévôt, G.; Prieto, H.; Putis, M.; Reardon, P.; Reyes, M.; Ricci, M.; Rodríguez, I.; Rodríguez Frías, M. D.; Ronga, F.; Roth, M.; Rothkaehl, H.; Roudil, G.; Rusinov, I.; Rybczyński, M.; Sabau, M. D.; Sáez-Cano, G.; Sagawa, H.; Saito, A.; Sakaki, N.; Sakata, M.; Salazar, H.; Sánchez, S.; Santangelo, A.; Santiago Crúz, L.; Sanz Palomino, M.; Saprykin, O.; Sarazin, F.; Sato, H.; Sato, M.; Schanz, T.; Schieler, H.; Scotti, V.; Segreto, A.; Selmane, S.; Semikoz, D.; Serra, M.; Sharakin, S.; Shibata, T.; Shimizu, H. M.; Shinozaki, K.; Shirahama, T.; Siemieniec-Oziȩbło, G.; Silva López, H. H.; Sledd, J.; Słomińska, K.; Sobey, A.; Sugiyama, T.; Supanitsky, D.; Suzuki, M.; Szabelska, B.; Szabelski, J.; Tajima, F.; Tajima, N.; Tajima, T.; Takahashi, Y.; Takami, H.; Takeda, M.; Takizawa, Y.; Tenzer, C.; Tibolla, O.; Tkachev, L.; Tokuno, H.; Tomida, T.; Tone, N.; Toscano, S.; Trillaud, F.; Tsenov, R.; Tsunesada, Y.; Tsuno, K.; Tymieniecka, T.; Uchihori, Y.; Unger, M.; Vaduvescu, O.; Valdés-Galicia, J. F.; Vallania, P.; Valore, L.; Vankova, G.; Vigorito, C.; Villaseñor, L.; von Ballmoos, P.; Wada, S.; Watanabe, J.; Watanabe, S.; Watts, J.; Weber, M.; Weiler, T. J.; Wibig, T.; Wiencke, L.; Wille, M.; Wilms, J.; Włodarczyk, Z.; Yamamoto, T.; Yamamoto, Y.; Yang, J.; Yano, H.; Yashin, I. V.; Yonetoku, D.; Yoshida, K.; Yoshida, S.; Young, R.; Zotov, M. Yu.; Zuccaro Marchi, A.

    2015-11-01

    In this paper we describe the main characteristics of the JEM-EUSO instrument. The Extreme Universe Space Observatory on the Japanese Experiment Module (JEM-EUSO) of the International Space Station (ISS) will observe Ultra High-Energy Cosmic Rays (UHECR) from space. It will detect UV-light of Extensive Air Showers (EAS) produced by UHECRs traversing the Earth's atmosphere. For each event, the detector will determine the energy, arrival direction and the type of the primary particle. The advantage of a space-borne detector resides in the large field of view, using a target volume of about 1012 tons of atmosphere, far greater than what is achievable from ground. Another advantage is a nearly uniform sampling of the whole celestial sphere. The corresponding increase in statistics will help to clarify the origin and sources of UHECRs and characterize the environment traversed during their production and propagation. JEM-EUSO is a 1.1 ton refractor telescope using an optics of 2.5 m diameter Fresnel lenses to focus the UV-light from EAS on a focal surface composed of about 5,000 multi-anode photomultipliers, for a total of ≃3ṡ105 channels. A multi-layer parallel architecture handles front-end acquisition, selecting and storing valid triggers. Each processing level filters the events with increasingly complex algorithms using FPGAs and DSPs to reject spurious events and reduce the data rate to a value compatible with downlink constraints.

  20. Electronic instrumentation for smart structures

    NASA Astrophysics Data System (ADS)

    Blanar, George J.

    1995-04-01

    The requirements of electronic instrumentation for smart structures are similar to those of data acquisition systems at our national particle physics laboratories. Modern high energy and heavy ion physics experiments may have tens of thousands of channels of data sources producing data that must be converted to digital form, compacted, stored and interpreted. In parallel, multiple sensors distributed in and around smart structures generate either binary or analog signals that are voltage, charge, or time like in their information content. In all cases, they must be transmitted, converted and preserved into a unified digital format for real-time processing. This paper will review the current status of practical large scale electronic measurement systems with special attention to architectures and physical organization. Brief surveys of the current state of the art will include preamplifiers and amplifiers, comparators and discriminators, voltage or charge analog-to-digital converters, time internal meters or time-to-digital converters, and finally, counting or scalar systems. The paper will conclude by integrating all of these ideas in a concept for an all-digital readout of a smart structure using the latest techniques used in physics research today.

  1. Instrumentation, Control, and Intelligent Systems

    SciTech Connect

    Not Available

    2005-09-01

    Abundant and affordable energy is required for U.S. economic stability and national security. Advanced nuclear power plants offer the best near-term potential to generate abundant, affordable, and sustainable electricity and hydrogen without appreciable generation of greenhouse gases. To that end, Idaho National Laboratory (INL) has been charged with leading the revitalization of nuclear power in the U.S. The INL vision is to become the preeminent nuclear energy laboratory with synergistic, world-class, multi-program capabilities and partnerships by 2015. The vision focuses on four essential destinations: (1) Be the preeminent internationally-recognized nuclear energy research, development, and demonstration laboratory; (2) Be a major center for national security technology development and demonstration; (3) Be a multi-program national laboratory with world-class capabilities; (4) Foster academic, industry, government, and international collaborations to produce the needed investment, programs, and expertise. Crucial to that effort is the inclusion of research in advanced instrumentation, control, and intelligent systems (ICIS) for use in current and advanced power and energy security systems to enable increased performance, reliability, security, and safety. For nuclear energy plants, ICIS will extend the lifetime of power plant systems, increase performance and power output, and ensure reliable operation within the system's safety margin; for national security applications, ICIS will enable increased protection of our nation's critical infrastructure. In general, ICIS will cost-effectively increase performance for all energy security systems.

  2. Lidar instruments proposed for Eos

    NASA Technical Reports Server (NTRS)

    Grant, William B.; Browell, Edward V.

    1990-01-01

    Lidar, an acronym for light detection and ranging, represents a class of instruments that utilize lasers to send probe beams into the atmosphere or onto the surface of the Earth and detect the backscattered return in order to measure properties of the atmosphere or surface. The associated technology has matured to the point where two lidar facilities, Geodynamics Laser Ranging System (GLRS), and Laser Atmospheric Wind Sensor (LAWS) were accepted for Phase 2 studies for Eos. A third lidar facility Laser Atmospheric Sounder and Altimeter (LASA), with the lidar experiment EAGLE (Eos Atmospheric Global Lidar Experiment) was proposed for Eos. The generic lidar system has a number of components. They include controlling electronics, laser transmitters, collimating optics, a receiving telescope, spectral filters, detectors, signal chain electronics, and a data system. Lidar systems that measure atmospheric constituents or meteorological parameters record the signal versus time as the beam propagates through the atmosphere. The backscatter arises from molecular (Rayleigh) and aerosol (Mie) scattering, while attenuation arises from molecular and aerosol scattering and absorption. Lidar systems that measure distance to the Earth's surface or retroreflectors in a ranging mode record signals with high temporal resolution over a short time period. The overall characteristics and measurements objectives of the three lidar systems proposed for Eos are given.

  3. Bubble Measuring Instrument and Method

    NASA Technical Reports Server (NTRS)

    Kline-Schoder, Robert (Inventor); Magari, Patrick J. (Inventor)

    2002-01-01

    Method and apparatus are provided for a non-invasive bubble measuring instrument operable for detecting, distinguishing, and counting gaseous embolisms such as bubbles over a selectable range of bubble sizes of interest. A selected measurement volume in which bubbles may be detected is insonified by two distinct frequencies from a pump transducer and an image transducer, respectively. The image transducer frequency is much higher than the pump transducer frequency. The relatively low-frequency pump signal is used to excite bubbles to resonate at a frequency related to their diameter. The image transducer is operated in a pulse-echo mode at a controllable repetition rate that transmits bursts of high-frequency ultrasonic signal to the measurement volume in which bubbles may be detected and then receives the echo. From the echo or received signal, a beat signal related to the repetition rate may be extracted and used to indicate the presence or absence of a resonant bubble. In a preferred embodiment, software control maintains the beat signal at a preselected frequency while varying the pump transducer frequency to excite bubbles of different diameters to resonate depending on the range of bubble diameters selected for investigation.

  4. Bubble Measuring Instrument and Method

    NASA Technical Reports Server (NTRS)

    Kline-Schoder, Robert (Inventor); Magari, Patrick J. (Inventor)

    2002-01-01

    Method and apparatus are provided for a non-invasive bubble measuring instrument operable for detecting. distinguishing, and counting gaseous embolisms such as bubbles over a selectable range of bubble sizes of interest. A selected measurement volume in which bubbles may be detected is insonified by two distinct frequencies from a pump transducer and an image transducer, respectively. The image transducer frequency is much higher than the pump transducer frequency. The relatively low-frequency pump signal is used to excite bubbles to resonate at a frequency related to their diameter. The image transducer is operated in a pulse-echo mode at a controllable repetition rate that transmits bursts of high-frequency ultrasonic signal to the measurement volume in which bubbles may be detected and then receive, the echo. From the echo or received signal, a beat signal related to the repetition rate may be extracted and used to indicate the presence or absence of a resonant bubble. In a preferred embodiment, software control maintains the beat signal at a preselected frequency while varying the pump transducer frequency to excite bubbles of different diameters to resonate depending on the range of bubble diameters selected for investigation.

  5. Tokamak x ray diagnostic instrumentation

    SciTech Connect

    Hill, K.W.; Beiersdorfer, P.; Bitter, M.; Fredrickson, E.; Von Goeler, S.; Hsuan, H.; Johnson, L.C.; Liew, S.L.; McGuire, K.; Pare, V.

    1987-01-01

    Three classes of x-ray diagnostic instruments enable measurement of a variety of tokamak physics parameters from different features of the x-ray emission spectrum. (1) The soft x-ray (1 to 50 keV) pulse-height-analysis (PHA) diagnostic measures impurity concentrations from characteristic line intensities and the continuum enhancement, and measures the electron temperature from the continuum slope. (2) The Bragg x-ray crystal spectrometer (XCS) measures the ion temperature and neutral-beam-induced toroidal rotation velocity from the Doppler broadening and wavelength shift, respectively, of spectral lines of medium-Z impurity ions. Impurity charge state distributions, precise wavelengths, and inner-shell excitation and recombination rates can also be studied. X rays are diffracted and focused by a bent crystal onto a position-sensitive detector. The spectral resolving power E/..delta..E is greater than 10/sup 4/ and time resolution is 10 ms. (3) The x-ray imaging system (XIS) measures the spatial structure of rapid fluctuations (0.1 to 100 kHZ) providing information on MHD phenomena, impurity transport rates, toroidal rotation velocity, plasma position, and the electron temperature profile. It uses an array of silicon surface-barrier diodes which view different chords of the plasma through a common slot aperture and operate in current (as opposed to counting) mode. The effectiveness of shields to protect detectors from fusion-neutron radiation effects has been studied both theoretically and experimentally.

  6. New instruments for solar research

    NASA Technical Reports Server (NTRS)

    Rust, David M.; O'Byrne, John W.; Sterner, Raymond E., II

    1990-01-01

    In fulfilment of its goal to develop early detection and warning of emerging solar magnetic fields, the Center for Applied Solar Physics (CASP) has designed and constructed a solar vector magnetograph (VMG) that will provide unique data on the sunspot regions where flares originate. The instrument is reportedly beginning to approach its goals of measuring all three components of the solar magnetic field with a sensitivity of 50 to 100 G and a spatial resolution on the sun of about 700 km (1 arcsec). Importance of new high-resolution capabilities is stressed and the interpretation of VMG measurements is discussed. The performance of the solar VMG, installed in a 6-m dome at the National Solar Observatory at Sacramento Peak in Sunspot, New Mexico, and its construction and environment are described; particular attention is given to the use and function of the filters. Initial results are examined, including a description and analysis of a magnetogram obtained after installation of an improved blocking filter.

  7. Kids with disabilities inspire a musical instrument

    SciTech Connect

    Daily, Dan; Pfeifer, Kent

    2013-11-21

    The Midiwing is a musical instrument that unites music and computer technology for those who lack the experience, physical ability, or maturity to play music with traditional instruments. To create the instrument, Dan Daily, Director of Musicode Innovations, reworked and recoded Musical Instrument Digital Interface (MIDI) technology and introduced ergonomic design. He applied to the New Mexico Small Business Assistance (NMSBA) Program to receive help when he discovered the microcontroller he used was being phased out. Daily and Kent Pfeifer, an engineer at Sandia National Laboratories and musician himself, partnered to create a new state-of-the-art design.

  8. Kids with disabilities inspire a musical instrument

    ScienceCinema

    Daily, Dan; Pfeifer, Kent

    2016-07-12

    The Midiwing is a musical instrument that unites music and computer technology for those who lack the experience, physical ability, or maturity to play music with traditional instruments. To create the instrument, Dan Daily, Director of Musicode Innovations, reworked and recoded Musical Instrument Digital Interface (MIDI) technology and introduced ergonomic design. He applied to the New Mexico Small Business Assistance (NMSBA) Program to receive help when he discovered the microcontroller he used was being phased out. Daily and Kent Pfeifer, an engineer at Sandia National Laboratories and musician himself, partnered to create a new state-of-the-art design.

  9. Rotary mode system initial instrument calibration

    SciTech Connect

    Johns, B.R.

    1994-10-01

    The attached report contains the vendor calibration procedures used for the initial instrument calibration of the rotary core sampling equipment. The procedures are from approved vendor information files.

  10. Recent Topics in Instrumentation and Measurement

    NASA Astrophysics Data System (ADS)

    Tanabe, Kazuo; Hirose, Masanobu; Otani, Akihito; Mochizuki, Ken; Uchida, Masafumi

    Instrumentation and measurement play a vital role in research and development in the science and engineering fields. Recently, the goals of instrumentation and measurement have expanded to meet not only the industrial and science requirements but also the needs in all fields of social life, such as medicine and welfare, the environment, and disaster and security. In this article, the state of TC-IM (Technical Committee of Instrumentation and Measurement of IEEJ) activities and technical topics in the instrumentation and measurement field are reported, mainly referring to over seventy papers presented at the IM Technical Meeting.

  11. 14 CFR 33.29 - Instrument connection.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... associated wiring and signal conditioning, must be segregated, electrically and physically, to the extent necessary to ensure that the probability of a fault propagating from instrumentation and...

  12. Ultraviolet fluorescence water vapor instrument for aircraft

    NASA Astrophysics Data System (ADS)

    Stone, E. J.

    1980-05-01

    An ultraviolet-fluorescence instrument for the measurement of stratospheric water vapor concentrations has been developed and flown on balloon-parachute vehicles. The adaptation of the instrument to aircraft is reported, noting that it can be used at all altitudes above 400 mb. The air is ducted at 30 m/s from a heated intake above the roof of the aircraft through an 1.5-in. diameter pipe and the sensitivity of the instrument is 260 counts/s per ppmv of water vapor with a standard deviation plus or minus 15%. The instrument exhibits fast response, good resistance to contamination and direct calibration in use.

  13. CICADA, CCD and Instrument Control Software

    NASA Astrophysics Data System (ADS)

    Young, Peter J.; Brooks, Mick; Meatheringham, Stephen J.; Roberts, William H.

    Computerised Instrument Control and Data Acquisition (CICADA) is a software system for control of telescope instruments in a distributed computing environment. It is designed using object-oriented techniques and built with standard computing tools such as RPC, SysV IPC, Posix threads, Tcl, and GUI builders. The system is readily extensible to new instruments and currently supports the Astromed 3200 CCD controller and MSSSO's new tip-tilt system. Work is currently underway to provide support for the SDSU CCD controller and MSSSO's Double Beam Spectrograph. A core set of processes handle common communication and control tasks, while specific instruments are ``bolted'' on using C++ inheritance techniques.

  14. The Relationship between Postsecondary Instrumental Student's Musical Independence and Grade-Level, Instrument Family, Gender, and Instrumental Ensemble.

    ERIC Educational Resources Information Center

    Bobbett, Gordon C.; And Others

    This study analyzed the relationship between MI (musical independence) and placement in college instrumental ensembles, the influence of instrument family and gender on the development of MI in postsecondary students, and identification of those outstanding MI students most at risk of dropping music as their college major. Instrumentalists (N=354)…

  15. [What's new in instrumental dermatology?].

    PubMed

    Amici, J-M

    2014-12-01

    This "What's new in instrumental dermatology" focuses on cutaneous oncologic surgery, base on a review of the 2012-2014 literature. First, the ability of dermatologists to make a good "oncologic reading of tumors" is the key of radical surgical treatment. Advantages and disadvantages of the biopsy are discussed. Then, the second message is the management of anticoagulants, that should not be interrupted for skin surgery. Despite recommendations, this practice is not followed in 40% of cases; this point is critical because bleeding complications are minor compared to potential morbidity of thrombotic events when stopping these medications. Regarding infection, nasal carriage of Staphylococcus aureus is identified as a risk factor for wound infection. A preoperative shower with chlorhexidine and mupirocin topical decolonization of nostril reduces this risk. Surgical techniques are trying to reach minimalism, by reducing undermining and scarring. On the trunk, using deep slow resorbable sutures improve scarring. In addition using adhesive sutures (strip) reduce the wideness of scar. On the face, the lower third of the nose is the most challenging because of the free edges, which are deformable. In this location bilobed or trilobed transposition flap offer the advantage of remaining in the nasal aesthetic unit and not disturbing the free edges of the nasal orifices. Regarding scarring, early hypertrophic scar is now well defined and linked with transposition flaps of the nasal region. An early treatment with intralesional corticosteroid injection appears to be effective. Finally, the biological mechanism of the effectiveness of compression in the prevention and treatment of dystrophic scar is now clear. The mechanotransduction explain how a mechanical stress of the skin activates biological cell pathways, which regulate the quality of collagen synthesis and the arrangement of skin fibrosis.

  16. Images from Phoenix's MECA Instruments

    NASA Technical Reports Server (NTRS)

    2008-01-01

    The image on the upper left is from NASA's Phoenix Mars Lander's Optical Microscope after a sample informally called 'Sorceress' was delivered to its silicon substrate on the 38th Martian day, or sol, of the mission (July 2, 2008).

    A 3D representation of the same sample is on the right, as seen by Phoenix's Atomic Force Microscope. This is 200 times greater magnification than the view from the Optical Microscope, and the most highly magnified image ever seen from another world.

    The image shows four round pits, only 5 microns in depth, that were micromachined into the silicon substrate, which is the background plane shown in red. This image has been processed to reflect the levelness of the substrate.

    A Martian particle only one micrometer, or one millionth of a meter, across is held in the upper left pit.

    The rounded particle shown at the highest magnification ever seen from another world is a particle of the dust that cloaks Mars. Such dust particles color the Martian sky pink, feed storms that regularly envelop the planet and produce Mars' distinctive red soil.

    The Optical Microscope and the Atomic Force Microscope are part of Phoenix's Microscopy, Electrochemistry and Conductivity Analyzer instrument.

    The AFM was developed by a Swiss-led consortium, with Imperial College London producing the silicon substrate that holds sampled particles.

    The Phoenix Mission is led by the University of Arizona, Tucson, on behalf of NASA. Project management of the mission is by NASA's Jet Propulsion Laboratory, Pasadena, Calif. Spacecraft development is by Lockheed Martin Space Systems, Denver.

  17. Ozone Monitoring Instrument geolocation verification

    NASA Astrophysics Data System (ADS)

    Kroon, M.; Dobber, M. R.; Dirksen, R.; Veefkind, J. P.; van den Oord, G. H. J.; Levelt, P. F.

    2008-08-01

    Verification of the geolocation assigned to individual ground pixels as measured by the Ozone Monitoring Instrument (OMI) aboard the NASA EOS-Aura satellite was performed by comparing geophysical Earth surface details as observed in OMI false color images with the high-resolution continental outline vector map as provided by the Interactive Data Language (IDL) software tool from ITT Visual Information Solutions. The OMI false color images are generated from the OMI visible channel by integration over 20-nm-wide spectral bands of the Earth radiance intensity around 484 nm, 420 nm, and 360 nm wavelength per ground pixel. Proportional to the integrated intensity, we assign color values composed of CRT standard red, green, and blue to the OMI ground pixels. Earth surface details studied are mostly high-contrast coast lines where arid land or desert meets deep blue ocean. The IDL high-resolution vector map is based on the 1993 CIA World Database II Map with a 1-km accuracy. Our results indicate that the average OMI geolocation offset over the years 2005-2006 is 0.79 km in latitude and 0.29 km in longitude, with a standard deviation of 1.64 km in latitude and 2.04 km in longitude, respectively. Relative to the OMI nadir pixel size, one obtains mean displacements of ˜6.1% in latitude and ˜1.2% in longitude, with standard deviations of 12.6% and 7.9%, respectively. We conclude that the geolocation assigned to individual OMI ground pixels is sufficiently accurate to support scientific studies of atmospheric features as observed in OMI level 2 satellite data products, such as air quality issues on urban scales or volcanic eruptions and its plumes, that occur on spatial scales comparable to or smaller than OMI nadir pixels.

  18. [What's new in instrumental dermatology?].

    PubMed

    Amici, J-M

    2014-12-01

    This "What's new in instrumental dermatology" focuses on cutaneous oncologic surgery, base on a review of the 2012-2014 literature. First, the ability of dermatologists to make a good "oncologic reading of tumors" is the key of radical surgical treatment. Advantages and disadvantages of the biopsy are discussed. Then, the second message is the management of anticoagulants, that should not be interrupted for skin surgery. Despite recommendations, this practice is not followed in 40% of cases; this point is critical because bleeding complications are minor compared to potential morbidity of thrombotic events when stopping these medications. Regarding infection, nasal carriage of Staphylococcus aureus is identified as a risk factor for wound infection. A preoperative shower with chlorhexidine and mupirocin topical decolonization of nostril reduces this risk. Surgical techniques are trying to reach minimalism, by reducing undermining and scarring. On the trunk, using deep slow resorbable sutures improve scarring. In addition using adhesive sutures (strip) reduce the wideness of scar. On the face, the lower third of the nose is the most challenging because of the free edges, which are deformable. In this location bilobed or trilobed transposition flap offer the advantage of remaining in the nasal aesthetic unit and not disturbing the free edges of the nasal orifices. Regarding scarring, early hypertrophic scar is now well defined and linked with transposition flaps of the nasal region. An early treatment with intralesional corticosteroid injection appears to be effective. Finally, the biological mechanism of the effectiveness of compression in the prevention and treatment of dystrophic scar is now clear. The mechanotransduction explain how a mechanical stress of the skin activates biological cell pathways, which regulate the quality of collagen synthesis and the arrangement of skin fibrosis. PMID:25539752

  19. 14 CFR 23.1337 - Powerplant instruments installation.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Powerplant instruments installation. 23... Equipment Instruments: Installation § 23.1337 Powerplant instruments installation. (a) Instruments and instrument lines. (1) Each powerplant and auxiliary power unit instrument line must meet the requirements...

  20. Aeronautic instruments. Section I : general classification of instruments and problems including bibliography

    NASA Technical Reports Server (NTRS)

    Hersey, Mayo D

    1923-01-01

    This report is intended as a technical introduction to the series of reports on aeronautic instruments. It presents a discussion of those subjects which are common to all instruments. First, a general classification is given, embracing all types of instruments used in aeronautics. Finally, a classification is given of the various problems confronted by the instrument expert and investigator. In this way the following groups of problems are brought up for consideration: problems of mechanical design, human factor, manufacturing problems, supply and selection of instruments, problems concerning the technique of testing, problems of installation, problems concerning the use of instruments, problems of maintenance, and physical research problems. This enumeration of problems which are common to instruments in general serves to indicate the different points of view which should be kept in mind in approaching the study of any particular instrument.

  1. A laser tracking dynamic robot metrology instrument

    NASA Technical Reports Server (NTRS)

    Parker, G. A.; Mayer, J. R. R.

    1989-01-01

    Research work over several years has resulted in the development of a laser tracking instrument capable of dynamic 3-D measurements of robot end-effector trajectories. The instrument characteristics and experiments to measure the static and dynamic performance of a robot in an industrial manufacturing environment are described. The use of this technology for space applications is examined.

  2. General specifications covering requirements of aeronautic instruments

    NASA Technical Reports Server (NTRS)

    1917-01-01

    Report includes specifications for the use and production of instruments used in the navigation and operation of aircraft. Specifications are included for the following instruments: barometer or altimeter, compass, air speed meter, inclinometer, drift meter, tachometer, oil gauge, oil pressure gauge, gasoline gauge, gasoline flow indicator, distance indicator, barograph, angle of attack indicator, radiator temperature indicator, gasoline feed system pressure indicator, sextant, airplane director.

  3. VELA: A Microprocessor-Based Laboratory Instrument.

    ERIC Educational Resources Information Center

    Lambert, Andrew

    1983-01-01

    Provides a general description of a preprogramed, microprocessor-based laboratory instrument, discussing its use in monitoring: (1) environmental changes; (2) distribution of count rates from a radioactive source, and (3) motion on an air tract. Includes list of the instrument's various capabilities: frequency meter, voltmeter, interval timer, and…

  4. The measurement of fatigue: a new instrument.

    PubMed

    Schwartz, J E; Jandorf, L; Krupp, L B

    1993-10-01

    Fatigue is a frequent medical symptom which has not been routinely measured. We present a 29-item fatigue assessment instrument, describe its psychometric properties, and use it to differentiate normal fatigue from fatigue related medical disorders. Differences in fatigue across a variety of medical disorders, the reproducibility of the fatigue instrument, and its convergent validity with other fatigue measures are also described.

  5. 47 CFR 73.58 - Indicating instruments.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES RADIO BROADCAST SERVICES AM... indicating instruments which conform with the specifications described in § 73.1215 for determining power by... nominal power rating of 100 watts or less are not required to be equipped with instruments to...

  6. 40 CFR 201.22 - Measurement instrumentation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Measurement instrumentation. 201.22... PROGRAMS NOISE EMISSION STANDARDS FOR TRANSPORTATION EQUIPMENT; INTERSTATE RAIL CARRIERS Measurement Criteria § 201.22 Measurement instrumentation. (a) A sound level meter or alternate sound level...

  7. Effect of geotropism on instrument readings

    SciTech Connect

    Rolph, James T.

    2006-11-01

    A review of gravity's effect on instrument readings, also referred to as geotropism. In this essay a review of meter movement construction and the effect are reviewed as it applies to portable radiation instruments. Reference to the three ANSI standards and their requirements are reviewed. An alternate approach to test for the effects is offered.

  8. Career Ladder Instrumentation: The Tennessee Experience.

    ERIC Educational Resources Information Center

    McLarty, Joyce R.

    The evaluation instruments used in the Tennessee Career Ladder program are described, and their evolution over the first three years of program implementation is traced. The instruments are designed to measure teacher performance and to determine outstanding teachers. They include: the Career Ladder Test of Professional Skills (a multiple-choice…

  9. Computer-Aided Instruction in Automated Instrumentation.

    ERIC Educational Resources Information Center

    Stephenson, David T.

    1986-01-01

    Discusses functions of automated instrumentation systems, i.e., systems which combine electrical measuring instruments and a controlling computer to measure responses of a unit under test. The computer-assisted tutorial then described is programmed for use on such a system--a modern microwave spectrum analyzer--to introduce engineering students to…

  10. Adaptive Instruments for Students with Physical Disabilities

    ERIC Educational Resources Information Center

    Darrow, Alice-Ann

    2012-01-01

    The main adaptations that will be made for music students with physical disabilities are those that make the classroom accessible and those that make classroom instruments accessible. There are a number of principles to guide one when selecting instruments for students with physical disabilities. These principles can assist one in determining the…

  11. Instrumentation for measuring energy inputs to implements

    SciTech Connect

    Tompkins, F.D.; Wilhelm, L.R.

    1981-01-01

    A microcomputer-based instrumentation system for monitoring tractor operating parameters and energy inputs to implements was developed and mounted on a 75-power-takeoff-KW tractor. The instrumentation system, including sensors and data handling equipment, is discussed. 10 refs.

  12. Musical instruments from the Mayan culture

    NASA Astrophysics Data System (ADS)

    Rizo, Isabel Elena Romero; Redondo, Jose de Jesus Negrete; Paulin, Pablo Roberto Lizana

    2002-11-01

    This research work presents different kinds of sound generation instruments from the Mayan culture together with the Pablo Castellanos and Arturo Chamorro classification. It has to be noted that most of these musical instruments, whistles and noise generators are lost and some of them can only be seen on codex and museums. (To be presented in Spanish.)

  13. 76 FR 1063 - Modifications of Debt Instruments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-07

    ... FR 31736) that proposed amendments to Sec. 1.1001-3 to clarify the circumstances in which the credit... Internal Revenue Service 26 CFR Part 1 RIN 1545-BJ30 Modifications of Debt Instruments AGENCY: Internal... regulations relating to the modification of debt instruments. The regulations clarify the extent to which...

  14. 40 CFR 201.22 - Measurement instrumentation.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Measurement instrumentation. 201.22... PROGRAMS NOISE EMISSION STANDARDS FOR TRANSPORTATION EQUIPMENT; INTERSTATE RAIL CARRIERS Measurement Criteria § 201.22 Measurement instrumentation. (a) A sound level meter or alternate sound level...

  15. 40 CFR 201.22 - Measurement instrumentation.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Measurement instrumentation. 201.22... PROGRAMS NOISE EMISSION STANDARDS FOR TRANSPORTATION EQUIPMENT; INTERSTATE RAIL CARRIERS Measurement Criteria § 201.22 Measurement instrumentation. (a) A sound level meter or alternate sound level...

  16. 40 CFR 1066.120 - Measurement instruments.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Specifications § 1066.120 Measurement instruments. The measurement instrument requirements in 40 CFR part 1065, subpart C, apply with the following exceptions: (a) The provisions of § 1066.125 apply instead of 40 CFR 1065.202. (b) The provisions of 40 CFR 1065.210 and 1065.295 do not apply....

  17. Selected Instrumentation Films, 1969-1970.

    ERIC Educational Resources Information Center

    Simmons, Raymond L., Ed.

    This list of currently available films and filmstrips pertinent to instrumentation has been compiled from information solicited from many government and private sources. The 1969 compilation has been organized into the following eight categories: (1) principles of measurement and basic measurements; (2) analysis instrumentation; (3) automation and…

  18. Gender Differences in Musical Instrument Choice

    ERIC Educational Resources Information Center

    Hallam, Susan; Rogers, Lynne; Creech, Andrea

    2008-01-01

    Historically, there have been differences in the musical instruments played by boys and girls, with girls preferring smaller, higher-pitched instruments. This article explores whether these gender preferences have continued at a time when there is greater gender equality in most aspects of life in the UK. Data were collected from the 150 Music…

  19. Needed: Instruments as Good as Our Eyes

    ERIC Educational Resources Information Center

    Brickell, Henry M.

    2011-01-01

    Evaluators use their eyes to see what is there, whether it is intended or not. But they use their test instruments to measure what is intended, whether it is there or not. Evaluators have been broadening their repertoire of instruments for years: curriculum-embedded tests, observer checklists, audiotape recorders, videotape recorders, unobtrusive…

  20. An Analysis of Selected Skinfold Measuring Instruments.

    ERIC Educational Resources Information Center

    Hawkins, Jerald D.

    1983-01-01

    The performance of three relatively inexpensive skinfold calipers were compared with that of the Lange Skinfold Caliper. The instruments were used with 800 students ranging from elementary school to the college level. The Fat-O-Meter and Adipometer calipers compared favorably with the Lange instrument for accuracy and wearability while the…

  1. An Alternative Instrument for Private School Competition

    ERIC Educational Resources Information Center

    Cohen-Zada, D.

    2009-01-01

    Empirical studies estimating the effect of private school competition on student outcomes commonly use the share of Catholics in the local population as an instrument for private school competition. I show that this is not a valid instrument since it is endogenous to private school competition and suggest using instead the local share of Catholics…

  2. 19 CFR 10.41 - Instruments; exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Instruments; exceptions. 10.41 Section 10.41 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE... Traffic § 10.41 Instruments; exceptions. (a) Locomotives and other railroad equipment, trucks,...

  3. Guitar as the Preferred Musical Instrument

    ERIC Educational Resources Information Center

    Pelayo, Jose Maria G., III; Mallari, Shedy Dee C.; Pelayo, Jose Juancho S.

    2015-01-01

    The Guitar is a very popular instrument that is commonly used by many musicians. This study focused on the factors that made the guitar more appealing to the youth in comparison to other instruments. A semi structured, open ended questionnaire was used to collect the data essential for this study. 50 male and 50 female college students were…

  4. Instrumentation for Environmental Monitoring: Water, Volume 2.

    ERIC Educational Resources Information Center

    California Univ., Berkeley. Lawrence Berkeley Lab.

    This volume is one of a series discussing instrumentation for environmental monitoring. Each volume contains an overview of the basic problems, comparisons among the basic methods of sensing and detection, and notes that summarize the characteristics of presently available instruments and techniques. The text of this survey discusses the…

  5. Microfabricated field calibration assembly for analytical instruments

    DOEpatents

    Robinson, Alex L.; Manginell, Ronald P.; Moorman, Matthew W.; Rodacy, Philip J.; Simonson, Robert J.

    2011-03-29

    A microfabricated field calibration assembly for use in calibrating analytical instruments and sensor systems. The assembly comprises a circuit board comprising one or more resistively heatable microbridge elements, an interface device that enables addressable heating of the microbridge elements, and, in some embodiments, a means for positioning the circuit board within an inlet structure of an analytical instrument or sensor system.

  6. Unmanned Instrument Platform for Undersea Exploration

    NASA Technical Reports Server (NTRS)

    Paine, G.; Hansen, G. R.; Gulizia, R. W.; Paluzzi, P.

    1984-01-01

    Instruments accommodated on moving underwater platform. Towable underwater platform 3.2 meters long, 1.2 meters wide, 1.4 meters high and has mass of about 1,250 kilogram. Platform remotely operated and unmanned. Serves as test bed for development of ocean-measuring instruments and sonars at depths to 20,000 feet.

  7. Reading Instruments: Objects, Texts and Museums

    ERIC Educational Resources Information Center

    Anderson, Katharine; Frappier, Melanie; Neswald, Elizabeth; Trim, Henry

    2013-01-01

    Science educators, historians of science and their students often share a curiosity about historical instruments as a tangible link between past and present practices in the sciences. We less often integrate instruments into our research and pedagogy, considering artefact study as the domain of museum specialists. We argue here that scholars and…

  8. Measuring the instrument function of radiometers

    SciTech Connect

    Winston, R.; Littlejohn, R.G.

    1997-12-31

    The instrument function is a function of position and angle, the knowledge of which allows one to compute the response of a radiometer to an incident wave field in any state of coherence. The instrument function of a given radiometer need not be calculated; instead, it may be measured by calibration with incident plane waves.

  9. 47 CFR 73.58 - Indicating instruments.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... defective instrument is the antenna current meter of a nondirectional station which does not employ a remote antenna ammeter, or if the defective instrument is the common point meter of a station which employs a directional antenna and does not employ a remote common point meter, the operating power shall be...

  10. Void Fraction Instrument operation and maintenance manual

    SciTech Connect

    Borgonovi, G.; Stokes, T.I.; Pearce, K.L.; Martin, J.D.; Gimera, M.; Graves, D.B.

    1994-09-01

    This Operations and Maintenance Manual (O&MM) addresses riser installation, equipment and personnel hazards, operating instructions, calibration, maintenance, removal, and other pertinent information necessary to safely operate and store the Void Fraction Instrument. Final decontamination and decommissioning of the Void Fraction Instrument are not covered in this document.

  11. LEDA and APT beam diagnostics instrumentation

    SciTech Connect

    Gilpatrick, J.D.; Johnson, K.F.; Hodapp, T.R.

    1997-10-01

    A 20-MeV 100-mA-cw proton-accelerator, Low Energy Demonstration Accelerator (LEDA), is presently being developed, fabricated, and tested at Los Alamos National Laboratory (LANL). The beam diagnostic instrumentation for LEDA and the final 1700-GeV Accelerator Production of Tritium (APT) are classified into two categories: operation and characterization instrumentation. The operational instrumentation does not intercept or minimally-intercepts the beam and are sufficiently prompt and robust to provide accurate information to the operators and commissioners during full-current cw beam operation. The characterization instrumentation, primarily utilized during commissioning project-phases, operates under more traditional 100-mA-peak and approximately 0.1-mA-average beam-current conditions. This paper will review some of the LEDA and APT operational beam diagnostic instrumentation.

  12. Microbial contamination of musical wind instruments.

    PubMed

    Marshall, Bonnie; Levy, Stuart

    2011-08-01

    Retrospective and prospective studies were used to assess the numbers, types and persistence of microbes that contaminate wind instruments. All previously played instruments (n = 20) harbored viable bacteria as well as mold and/or yeast. Reedinstruments consistently carried higher microbial loads than did flutes or trumpets. Instruments played within the previous three days bore typical mouth flora, while bacteria recovered after 72 h following play consisted of normal environmental flora. Prospective studies tested survival of potentially pathogenic bacteria (Staphylococcus, Streptococcus, Moraxella, Escherichia coli and attenuated Mycobacterium tuberculosis) when applied to reeds or following simulated 'play' of a clarinet. All species survived for a maximum of 24-48 h on reeds, except Mycobacterium, which persisted through 13 days. In simulated play experiments, test bacteria could persist for up to five days. These findings support the establishment of guidelines for decontamination of wind instruments and for sharing or transfer of these instruments among players. PMID:21745020

  13. Microbial contamination of musical wind instruments.

    PubMed

    Marshall, Bonnie; Levy, Stuart

    2011-08-01

    Retrospective and prospective studies were used to assess the numbers, types and persistence of microbes that contaminate wind instruments. All previously played instruments (n = 20) harbored viable bacteria as well as mold and/or yeast. Reedinstruments consistently carried higher microbial loads than did flutes or trumpets. Instruments played within the previous three days bore typical mouth flora, while bacteria recovered after 72 h following play consisted of normal environmental flora. Prospective studies tested survival of potentially pathogenic bacteria (Staphylococcus, Streptococcus, Moraxella, Escherichia coli and attenuated Mycobacterium tuberculosis) when applied to reeds or following simulated 'play' of a clarinet. All species survived for a maximum of 24-48 h on reeds, except Mycobacterium, which persisted through 13 days. In simulated play experiments, test bacteria could persist for up to five days. These findings support the establishment of guidelines for decontamination of wind instruments and for sharing or transfer of these instruments among players.

  14. The cleaning of instruments and syringes

    PubMed Central

    Darmady, E. M.; Hughes, K. E. A.; Drewett, S. E.; Prince, D.; Tuke, Winifred; Verdon, Patricia

    1965-01-01

    The dangers to the handler of syringes used for routine injections were found to be negligible, but known infected syringes and those contaminated with antibiotics should be autoclaved before handling as a high proportion of these carry pathogenic organisms. Mechanical methods of cleaning syringes and instruments are assessed. The use of an artificial soil for testing purposes is described. Using this soil, ultrasonics by themselves are inadequate for cleaning syringes and instruments. Agitation with ultrasonics is essential for syringes, but is insufficient for instruments. Detergents are therefore an essential adjunct to the cleaning process. For syringes Pyroneg proved to be the most satisfactory, particularly if they had been previously siliconized. The best detergent for instruments contaminated with these types of soil was Penesolve 814 at a temperature of 95°C. but the instruments must be adequately rinsed after this treatment. A number of other detergents and cleaning agents are discussed. PMID:14247708

  15. Means for Positioning and Repositioning Scanning Instruments

    NASA Technical Reports Server (NTRS)

    Polites, Michael E. (Inventor); Alhorn, Dean C. (Inventor)

    1996-01-01

    A method is presented for positioning a scanning instrument to point toward the center of the desired scan wherein the scan is achieved by rotating unbalanced masses (RUMs) rotating about fixed axes of rotation relative to and associated with the instrument, the RUMs being supported on drive shafts spaced from the center of the mass of the instrument and rotating 180 degrees out-of-phase with each other and in planes parallel to each other to achieve the scan. The elevation and cross-elevation angles of the instrument are sensed to determine any offset and offset time rate-of-change, and the magnitude and direction are converted to a RUM cycle angular velocity component to be superimposed on the nominal velocity of the RUMs. This RUM angular velocity component modulates the RUM angular velocity to cause the speed of the RUMs to increase and decrease during each revolution to drive the instrument toward the desired center of the scan.

  16. The nonlinear physics of musical instruments

    NASA Astrophysics Data System (ADS)

    Fletcher, N. H.

    1999-05-01

    Musical instruments are often thought of as linear harmonic systems, and a first-order description of their operation can indeed be given on this basis, once we recognise a few inharmonic exceptions such as drums and bells. A closer examination, however, shows that the reality is very different from this. Sustained-tone instruments, such as violins, flutes and trumpets, have resonators that are only approximately harmonic, and their operation and harmonic sound spectrum both rely upon the extreme nonlinearity of their driving mechanisms. Such instruments might be described as `essentially nonlinear'. In impulsively excited instruments, such as pianos, guitars, gongs and cymbals, however, the nonlinearity is `incidental', although it may produce striking aural results, including transitions to chaotic behaviour. This paper reviews the basic physics of a wide variety of musical instruments and investigates the role of nonlinearity in their operation.

  17. Expandable and reconfigurable instrument node arrays

    NASA Technical Reports Server (NTRS)

    Hilliard, Lawrence M. (Inventor); Deshpande, Manohar (Inventor)

    2012-01-01

    An expandable and reconfigurable instrument node includes a feature detection means and a data processing portion in communication with the feature detection means, the data processing portion configured and disposed to process feature information. The instrument node further includes a phase locked loop (PLL) oscillator in communication with the data processing portion, the PLL oscillator configured and disposed to provide PLL information to the processing portion. The instrument node further includes a single tone transceiver and a pulse transceiver in communication with the PLL oscillator, the single tone transceiver configured and disposed to transmit or receive a single tone for phase correction of the PLL oscillator and the pulse transceiver configured and disposed to transmit and receive signals for phase correction of the PLL oscillator. The instrument node further includes a global positioning (GPA) receiver in communication with the processing portion, the GPS receiver configured and disposed to establish a global position of the instrument node.

  18. An Attitude Scale on Individual Instrument and Individual Instrument Course: Validity-Reliability Research

    ERIC Educational Resources Information Center

    Kuçukosmanoglu, Hayrettin Onur

    2015-01-01

    The main purpose of this study is to develop a scale to determine students' attitude levels on individual instruments and individual instrument courses in instrument training, which is an important dimension of music education, and to conduct a validity-reliability research of the scale that has been developed. The scale consists of 16 items. The…

  19. Gender Association of Musical Instruments and Preferences of Fourth-Grade Students for Selected Instruments.

    ERIC Educational Resources Information Center

    Delzell, Judith K.; Leppla, David A.

    1992-01-01

    Provides research findings concerning the musical instrument preferences of fourth grade students. Finds that, although gender associations with certain instruments have lessened, they remain noticeably present. Identifies drums, saxophone, and flute as the most popular instruments. Notes a moderate relationship between student perceptions of peer…

  20. Advanced Instrumentation for Extreme Environments

    SciTech Connect

    Melin, Alexander M; Kisner, Roger; Fugate, David L

    2013-01-01

    The Department of Energy (DOE) Office of Nuclear Energy (NE) is pursuing embedded instrumentation and controls (I&C) technology for next generation nuclear power generation applications. Embedded systems encompass a wide range of configurations and technologies; we define embedding in this instance as the integration of the sensors and the control system design into the component design using a systems engineering process. Embedded I&C systems are often an essential part of developing new capabilities, improving reliability, enhancing performance, and reducing operational costs. The new intrinsically safe, more efficient, and cost effective reactor technologies (Next Generation Nuclear Plant and Small Modular Reactors) require the development and application of new I&C technologies. These new designs raise extreme environmental challenges such as high temperatures (over 700 C) and material compatibility (e.g., molten salts). The desired reliability and functionality requires measurements in these extreme conditions including high radiation environments which were not previously monitored in real time. The DOE/NE Nuclear Energy Enabling Technologies (NEET) program currently has several projects investigating I&C technologies necessary to make these reactor designs realizable. The project described in this paper has the specific goal of investigating embedded I&C with the following objectives: 1.Explore and quantify the potential gains from embedded I&C improved reliability, increased performance, and reduced cost 2.Identify practical control, sensing, and measurement techniques for the extreme environments found in high-temperature reactors 3.Design and fabricate a functional prototype high-temperature cooling pump for molten salts represents target demonstration of improved performance, reliability, and widespread usage There are many engineering challenges in the design of a high-temperature liquid salt cooling pump. The pump and motor are in direct contact with