Authentic Science Research Opportunities: How Do Undergraduate Students Begin Integration into a Science Community of Practice?

ERIC Educational Resources Information Center

Gardner, Grant E.; Forrester, Jennifer H.; Jeffrey, Penny Shumaker; Ferzli, Miriam; Shea, Damian

2015-01-01

The goal of the study described was to understand the process and degree to which an undergraduate science research program for rising college freshmen achieved its stated objectives to integrate participants into a community of practice and to develop students' research identities.

IEEE Computer Society/Software Engineering Institute Watts S. Humphrey Software Process Achievement Award 2016: Raytheon Integrated Defense Systems Design for Six Sigma Team

DTIC Science & Technology

2017-04-01

notice for non -US Government use and distribution. External use: This material may be reproduced in its entirety, without modification, and freely...Combinatorial Design Methods 4 2.1 Identification of Significant Improvement Opportunity 4 2.2 Methodology Development 4 2.3 Piloting...11 3 Process Performance Modeling and Analysis 13 3.1 Identification of Significant Improvement Opportunity 13 3.2 Methodology Development 13 3.3

Planning for the integration of the digital library, clinical decision support, and evidence at the point of care.

PubMed

Schwartz, Linda Matula; Iobst, Barbara

2008-01-01

Integrating knowledge-based resources at the point of care is an important opportunity for hospital library involvement. In the progression of an IAIMS planning grant, the digital library is recognized as pivotal to the success of information domain integration throughout the institution. The planning process, data collection, and evolution of the planning project are discussed.

Arbitrage with fractional Gaussian processes

NASA Astrophysics Data System (ADS)

Zhang, Xili; Xiao, Weilin

2017-04-01

While the arbitrage opportunity in the Black-Scholes model driven by fractional Brownian motion has a long history, the arbitrage strategy in the Black-Scholes model driven by general fractional Gaussian processes is in its infancy. The development of stochastic calculus with respect to fractional Gaussian processes allowed us to study such models. In this paper, following the idea of Shiryaev (1998), an arbitrage strategy is constructed for the Black-Scholes model driven by fractional Gaussian processes, when the stochastic integral is interpreted in the Riemann-Stieltjes sense. Arbitrage opportunities in some fractional Gaussian processes, including fractional Brownian motion, sub-fractional Brownian motion, bi-fractional Brownian motion, weighted-fractional Brownian motion and tempered fractional Brownian motion, are also investigated.

An Ever-Changing Meaning: A Career Constructivist Application to Working with African Refugees

ERIC Educational Resources Information Center

Pierce, L. Marinn; Gibbons, Melinda M.

2012-01-01

Refugees are expected to determine how to integrate past experiences into their lives in a new culture. Constructivist approaches to counseling allow refugees opportunities to determine how to integrate these experiences into their future career choices. Refugee experiences throughout the resettlement process and a constructivist career counseling…

A Strategic Planning Approach to Technology Integration: Critical Success Factors.

ERIC Educational Resources Information Center

Shaw, Sam; Zabudsky, Jeff

Within most institutions of higher learning, the typical approach to the integration of new information and communications technologies into the teaching and learning process has involved a heavy reliance on early adopters. This path of least resistance approach has provided organizations with the opportunity to quickly claim a presence in the…

Tackling risks at the broad scale in the Interior Columbia Basin.

Treesearch

Sally Duncan

1998-01-01

Examining biophysical and social conditions, trends, and opportunities, the Columbia basin assessment draws a composite picture of the basin with two integrated measures: ecological integrity (the presence and functioning of ecological components and processes) and socioeconomic resiliency (the social and economic adaptability of a geographic area to outside economic...

An Enterprise System and a Business Simulation Provide Many Opportunities for Interdisciplinary Teaching

ERIC Educational Resources Information Center

Kreie, Jennifer; Shannon, James; Mora-Monge, Carlo A.

2011-01-01

Enterprise systems provide companies with centralized data management, business process support and integrated data flow between functional areas. Thanks to academic alliances offered by companies such as SAP, Oracle, Microsoft and others, universities can also take advantage of the integrated features of enterprise system to give business…

Targeted Therapies for Myeloma and Metastatic Bone Cancers

DTIC Science & Technology

2007-02-01

increased efficacy in the targeted microenvironment, and the ultimate opportunity to reverse catastrophic disease processes . Furthermore, targeted...concentrate the resulting nanoparticles using centrifuge concentrator tubes and we have integrated this processing step into our nanoparticle...is unaffected by this slightly altered approach. Furthermore, this modified method avoids a lengthy column separation process that diminishes the

Demonstration of an N7 integrated fab process for metal oxide EUV photoresist

NASA Astrophysics Data System (ADS)

De Simone, Danilo; Mao, Ming; Kocsis, Michael; De Schepper, Peter; Lazzarino, Frederic; Vandenberghe, Geert; Stowers, Jason; Meyers, Stephen; Clark, Benjamin L.; Grenville, Andrew; Luong, Vinh; Yamashita, Fumiko; Parnell, Doni

2016-03-01

Inpria has developed a directly patternable metal oxide hard-mask as a robust, high-resolution photoresist for EUV lithography. In this paper we demonstrate the full integration of a baseline Inpria resist into an imec N7 BEOL block mask process module. We examine in detail both the lithography and etch patterning results. By leveraging the high differential etch resistance of metal oxide photoresists, we explore opportunities for process simplification and cost reduction. We review the imaging results from the imec N7 block mask patterns and its process windows as well as routes to maximize the process latitude, underlayer integration, etch transfer, cross sections, etch equipment integration from cross metal contamination standpoint and selective resist strip process. Finally, initial results from a higher sensitivity Inpria resist are also reported. A dose to size of 19 mJ/cm2 was achieved to print pillars as small as 21nm.

Nanotechnology in the Chemical Industry - Opportunities and Challenges

NASA Astrophysics Data System (ADS)

Qiu Zhao, Qian; Boxman, Arthur; Chowdhry, Uma

2003-12-01

The traditional chemical industry has become a largely mature industry with many commodity products based on established technologies. Therefore, new product and market opportunities will more likely come from speciality chemicals, and from new functionalities obtained from new processing technologies as well as new microstructure control methodologies. It is a well-known fact that in addition to its molecular structure, the microstructure of a material is key to determining its properties. Controlling structures at the micro- and nano-levels is therefore essential to new discoveries. For this article, we define nanotechnology as the controlled manipulation of nanomaterials with at least one dimension less than 100nm. Nanotechnology is emerging as one of the principal areas of investigation that is integrating chemistry and materials science, and in some cases integrating these with biology to create new and yet undiscovered properties that can be exploited to gain new market opportunities. In this article market opportunities for nanotechnology will be presented from an industrial perspective covering electronic, biomedical, performance materials, and consumer products. Manufacturing technology challenges will be identified, including operations ranging from particle formation, coating, dispersion, to characterization, modeling, and simulation. Finally, a nanotechnology innovation roadmap is proposed wherein the interplay between the development of nanoscale building blocks, product design, process design, and value chain integration is identified. A suggestion is made for an R&D model combining market pull and technology push as a way to quickly exploit the advantages in nanotechnology and translate these into customer benefits.

Integrated structure/control design - Present methodology and future opportunities

NASA Technical Reports Server (NTRS)

Weisshaar, T. A.; Newsom, J. R.; Zeiler, T. A.; Gilbert, M. G.

1986-01-01

Attention is given to current methodology applied to the integration of the optimal design process for structures and controls. Multilevel linear decomposition techniques proved to be most effective in organizing the computational efforts necessary for ISCD (integrated structures and control design) tasks. With the development of large orbiting space structures and actively controlled, high performance aircraft, there will be more situations in which this concept can be applied.

Integrating Global Trends Information Into Army Strategic Planning Processes

DTIC Science & Technology

1993-06-01

There will inevitably be a need to clarify survey responses with the participants. Followup would also provide an opportunity to establish personal ...with the participants. Followup would also provide an opportunity to e~tablih personal contact with the experts, which would promote participation...Plublications Inc., Dallas, 1990). UNCITE!) Aaker , D.A. .Strategic Market Managemient, 2nd Edition. (New York: John Wiley. 1988). "Army Environmental

Commercial space opportunities - Advanced concepts and technology overview

NASA Technical Reports Server (NTRS)

Reck, Gregory M.

1993-01-01

The paper discusses the status of current and future commercial space opportunities. The goal is to pioneer innovative, customer-focused space concepts and technologies, leveraged through industrial, academic, and government alliance, to ensure U.S. commercial competitiveness and preeminence in space. The strategy is to develop technologies which enable new products and processes, deploy existing technology into commercial and military products and processes, and integrate military and commercial research and production activities. Technology development areas include information infrastructure, electronics design and manufacture, health care technology, environment technology, and aeronautical technologies.

Solvent recovery opportunities in the pharmaceutical industry.

PubMed

Barton, P I

2000-11-01

Opportunities for recovering and recycling waste solvent streams in the pharmaceutical industry are reviewed. A major obstacle to solvent recovery and recycling is the existence of azeotropic compositions, and thus separation barriers, in the mixtures in question. Advances in the understanding of these complex separation problems are discussed. Recent progress on novel designs for small-scale, flexible azeotropic separation processes is reviewed. Also considered is the alternative and complementary approach of integrating solvent use within a batch process so that the formation of hard-to-separate azeotropic compositions is prevented.

Employer Understanding of Work-Integrated Learning and the Challenges of Engaging in Work Placement Opportunities

ERIC Educational Resources Information Center

Jackson, Denise; Rowbottom, David; Ferns, Sonia; McLaren, Diane

2017-01-01

This study examines employer understanding of Work-Integrated Learning (WIL), reasons for participation and the challenges and barriers posed during the WIL process. This is important given the drive to grow WIL, augmented by the National Strategy for WIL, and the significant benefits it holds in preparing students for their transition to…

Framework for the Intelligent Transportation System (ITS) Evaluation : ITS Integration Activities

DOT National Transportation Integrated Search

2006-08-01

Intelligent Transportation Systems (ITS) represent a significant opportunity to improve the efficiency and safety of the surface transportation system. ITS includes technologies to support information processing, communications, surveillance and cont...

Projective Techniques in the Counseling Process.

ERIC Educational Resources Information Center

Clark, Arthur J.

1995-01-01

Projective techniques have evoked a minimal degree of interest on the part of counselors due to psychometric limitations, lack of training opportunities, and the obscure qualities of the instruments. The author proposes a method to stimulate the use of projectives as an integral part of the counseling process and provides justification for the…

Education for All and National Legislation

ERIC Educational Resources Information Center

Singh, Kishore

2009-01-01

Right to education, which is an integral part of UNESCO's constitutional mission of ensuring "full and equal opportunities for education for all," is at the core of the Education for All process. While reforming education polices as part of this process, many countries have modernized and developed national legislation, often with technical…

Getting Involved in the IEP Process

ERIC Educational Resources Information Center

Kowalski, Ellen; Lieberman, Lauren J.; Daggett, Sara

2006-01-01

Although, in many districts, physical educators are integral members of the Individualized Education Program (designed for students with disabilities such as Down syndrome and autism), in other districts, physical educators are only partially involved in the process or are not given the opportunity to be involved at all. However, the physical…

An Overview of Opportunities for Waste Heat Recovery and Thermal Integration in the Primary Aluminum Industry

NASA Astrophysics Data System (ADS)

Nowicki, Cassandre; Gosselin, Louis

2012-08-01

Efficient smelters currently consume roughly 13 MWh of electricity per ton of aluminum, while roughly half of that energy is lost as thermal waste. Although waste heat is abundant, current thermal integration in primary aluminum facilities remains limited. This is due to both the low quality of waste heat available and the shortage of potential uses within reasonable distance of identified waste heat sources. In this article, we present a mapping of both heat dissipation processes and heat demands around a sample facility (Alcoa Deschambault Quebec smelter). Our primary aim is to report opportunities for heat recovery and integration in the primary aluminum industry. We consider potential heat-to-sink pairings individually and assess their thermodynamic potential for producing energy savings.

Introduction to Radar Signal and Data Processing: The Opportunity

DTIC Science & Technology

2006-09-01

SpA) Director of Analysis of Integrated Systems Group Via Tiburtina Km. 12.400 00131 Rome ITALY e.mail: afarina@selex-si.com Key words: radar...signal processing, data processing, adaptivity, space-time adaptive processing, knowledge based systems , CFAR. 1. SUMMARY This paper introduces to...the lecture series dedicated to the knowledge-based radar signal and data processing. Knowledge-based expert system (KBS) is in the realm of

Towards Integrating Primary Care with Cancer Care: A Regional Study of Current Gaps and Opportunities in Canada

PubMed Central

Sussman, Jonathan; Bainbridge, Daryl; Evans, William K.

2017-01-01

Background and Objectives: Better integration between cancer care systems and primary care physicians (PCPs) is a goal of most healthcare systems, but little direction exists on how this can be achieved. This study systematically examined the extent of integration between PCPs and a regional cancer program (RCP) to identify opportunities for improvement. Method: Cross-sectional survey of all practising PCPs in the region of interest using a study-specific instrument based on a three-tier conceptualization of integration. Results: Among the 473 PCPs who responded (63% response rate), perceived role clarity and the desire for greater involvement in patient care varied across the care trajectory. Specific gaps were identified in PCPs' understanding of the referral process and patient follow-up after treatment. Conclusion: Our novel survey of PCPs explicated the strategies that could improve their integration in cancer care, including mechanisms to support PCPs in the initial diagnosis of their patients and standardized post-treatment transition plans outlining care roles and responsibilities. PMID:28277204

Decision support for the integrated restoration and protection strategy of the Forest Service, Northern Region

Treesearch

Keith Reynolds; Barry Bollenbacher; Chip Fisher; Melissa Hart; Mary Manning; Eric Henderson; Bruce Sims

2016-01-01

This report documents a decision-support process developed in the U.S. Department of Agriculture, Forest Service, Northern Region to assess management opportunities as part of an ecosystem-based approach to management that emphasizes ecological resilience. The decision-support system described in this work implements what is known as the Integrated Restoration and...

An integrated approach to evaluating the economic costs of wildfire hazard reduction through wood utilization opportunities in the southwestern United States

Treesearch

Eini C. Lowell; Dennis R. Becker; Robert Rummer; Debra Larson; Linda Wadleigh

2008-01-01

This research provides an important step in the conceptualization and development of an integrated wildfire fuels reduction system from silvicultural prescription, through stem selection, harvesting, in-woods processing, transport, and market selection. Decisions made at each functional step are informed by knowledge about subsequent functions. Data on the resource...

An integrated approach to evaluating the economic costs of wildfire hazard reduction through wood utilization opportunities in the Southwestern United States

Treesearch

Eini C. Lowell; Dennis R. Becker; Robert Rummer; Debra Larson; Linda Wadleigh

2008-01-01

This research provides an important step in the conceptualization and development of an integrated wildfire fuels reduction system from silvicultural prescription, through stem selection, harvesting, in-woods processing, transport, and market selection. Decisions made at each functional step are informed by knowledge about subsequent functions. Data on the resource...

Enhancing Self-Awareness: Integrating Himalayan Art in a Career Planning Class

ERIC Educational Resources Information Center

Wang, Michelle

2013-01-01

The dilemma for many college students' job search process is their overwhelming desire to locate any job rather than to satisfy their true passions. Thus, a job search can become a highly instrumental, task-oriented process, preventing students' opportunity to discover themselves and their life's purpose. Self-awareness, however, is a central…

Competing power-generating technologies for the 21st century

NASA Astrophysics Data System (ADS)

Troost, G. K.

1994-04-01

Several new and advanced power-generating systems are presently being developed, e.g., fuel cells, advanced heat pumps, high-performance gas turbines. An analysis of these systems is presented and is based on projections of comparative studies and relevant trends. For advanced systems, a trade-off between efficiency gain and projected development cost is crucial. Projections for market conditions in the 21st century and, in particular, environmental issues are made in order to assess market-entry opportunities. Results from various case studies indicate challenging opportunities in process and metallurgical industries; several process-integrated configurations are being studied.

Examining the process of de novo gene birth: an educational primer on "integration of new genes into cellular networks, and their structural maturation".

PubMed

Frietze, Seth; Leatherman, Judith

2014-03-01

New genes that arise from modification of the noncoding portion of a genome rather than being duplicated from parent genes are called de novo genes. These genes, identified by their brief evolution and lack of parent genes, provide an opportunity to study the timeframe in which emerging genes integrate into cellular networks, and how the characteristics of these genes change as they mature into bona fide genes. An article by G. Abrusán provides an opportunity to introduce students to fundamental concepts in evolutionary and comparative genetics and to provide a technical background by which to discuss systems biology approaches when studying the evolutionary process of gene birth. Basic background needed to understand the Abrusán study and details on comparative genomic concepts tailored for a classroom discussion are provided, including discussion questions and a supplemental exercise on navigating a genome database.

Assessment of post-tsunami disaster recovery of Banda Aceh city of Indonesia as window of opportunities for sustainable development

NASA Astrophysics Data System (ADS)

Meilianda, E.; Munadi, K.; Azmeri; Safrida; Direzkia, Y.; Syamsidik; Oktari, R. S.

2017-02-01

Post-tsunami recovery process at Banda Aceh city of Indonesia were assessed in this study. Several actions and programs implemented during the recovery process were exercised and examined through several FGDs, to identify any windows of opportunities to change were captured in the aspects of infrastructure and housing, economic revitalization of the affected community, mental health and psychosocial condition and development, establishment and implementation of disaster risk reduction programs and community preparedness. Subsequently, whether or not those changes fit into the principle criteria of sustainability were examined. The results give insights on the dynamics of recovery process after more than a decade since the tsunami was affected the area. Some success and not-so-success stories of actions and program implementations during the recovery process were captured. On the aspect of livelihoods and public finance, the local government seems to have seen a window of opportunity and subsequently seize the opportunity to revitalize the administrative system of financing the micro-finance for communities. In contrast, on the aspect of socio-ecological systems integrity toward preserving the natural environment, the case of housing development at the coastal areas against the blueprint city masterplan exemplifies the failure in seizing the window of opportunity to “build back better”.

Semi-transparent solar cells

NASA Astrophysics Data System (ADS)

Sun, J.; Jasieniak, J. J.

2017-03-01

Semi-transparent solar cells are a type of technology that combines the benefits of visible light transparency and light-to-electricity conversion. One of the biggest opportunities for such technologies is in their integration as windows and skylights within energy-sustainable buildings. Currently, such building integrated photovoltaics (BIPV) are dominated by crystalline silicon based modules; however, the opaque nature of silicon creates a unique opportunity for the adoption of emerging photovoltaic candidates that can be made truly semi-transparent. These include: amorphous silicon-, kesterite-, chalcopyrite-, CdTe-, dye-sensitized-, organic- and perovskite- based systems. For the most part, amorphous silicon has been the workhorse in the semi-transparent solar cell field owing to its established, low-temperature fabrication processes. Excitement around alternative classes, particularly perovskites and the inorganic candidates, has recently arisen because of the major efficiency gains exhibited by these technologies. Importantly, each of these presents unique opportunities and challenges within the context of BIPV. This topic review provides an overview into the broader benefits of semi-transparent solar cells as building-integrated features, as well as providing the current development status into all of the major types of semi-transparent solar cells technologies.

Revisiting Organisational Learning in Integrated Care.

PubMed

Nuño-Solinís, Roberto

2017-08-11

Progress in health care integration is largely linked to changes in processes and ways of doing. These changes have knowledge management and learning implications. For this reason, the use of the concept of organisational learning is explored in the field of integrated care. There are very limited contributions that have connected the fields of organisational learning and care integration in a systematic way, both at the theoretical and empirical level. For this reason, hybridization of both perspectives still provides opportunities for understanding care integration initiatives from a research perspective as well as potential applications in health care management and planning.

Revisiting Organisational Learning in Integrated Care

PubMed Central

2017-01-01

Progress in health care integration is largely linked to changes in processes and ways of doing. These changes have knowledge management and learning implications. For this reason, the use of the concept of organisational learning is explored in the field of integrated care. There are very limited contributions that have connected the fields of organisational learning and care integration in a systematic way, both at the theoretical and empirical level. For this reason, hybridization of both perspectives still provides opportunities for understanding care integration initiatives from a research perspective as well as potential applications in health care management and planning. PMID:28970762

Integrating traditional nursing service orientation content with electronic medical record orientation.

PubMed

Harton, Brenda B; Borrelli, Larry; Knupp, Ann; Rogers, Necolen; West, Vickie R

2009-01-01

Traditional nursing service orientation classes at an acute care hospital were integrated with orientation to the electronic medical record to blend the two components in a user-friendly format so that the learner is introduced to the culture, processes, and documentation methods of the organization, with an opportunity to document online in a practice domain while lecture and discussion information is fresh.

Attaining and maintaining data integrity with configuration management

NASA Astrophysics Data System (ADS)

Huffman, Dorothy J.; Jeane, Shirley A.

1993-08-01

Managers and scientists are concerned about data integrity because they draw conclusions from data that can have far reaching effects. Projects managers use Configuration Management to insure that hardware, software, and project information are controlled. They have not, as yet, applied its rigorously to data. However, there is ample opportunity in the data collection and production process to jeopardize data integrity. Environmental changes, tampering and production problems can all affect data integrity. There are four functions included in the Configuration Management process: configuration identification, control, auditing and status accounting. These functions provide management the means to attain data integrity and the visibility into engineering processes needed to maintain data integrity. When project managers apply Configuration Management processes to data, the data user can trace back through history to validate data integrity. The user knows that the project allowed only orderly changes to the data. He is assured that project personnel followed procedures to maintain data quality. He also has access to status information about the data. The user receives data products with a known integrity level and a means to assess the impact of past events ont he conclusions derived from the data. To obtain these benefits, project managers should apply the Configuration Management discipline to data.

Creating a Pilot Educational Psychiatry Website: Opportunities, Barriers, and Next Steps.

PubMed

Torous, John; O'Connor, Ryan; Franzen, Jamie; Snow, Caitlin; Boland, Robert; Kitts, Robert

2015-11-05

While medical students and residents may be utilizing websites as online learning resources, medical trainees and educators now have the opportunity to create such educational websites and digital tools on their own. However, the process and theory of building educational websites for medical education have not yet been fully explored. To understand the opportunities, barriers, and process of creating a novel medical educational website. We created a pilot psychiatric educational website to better understand the options, opportunities, challenges, and processes involved in the creation of a psychiatric educational website. We sought to integrate visual and interactive Web design elements to underscore the potential of such Web technology. A pilot website (PsychOnCall) was created to demonstrate the potential of Web technology in medical and psychiatric education. Creating an educational website is now technically easier than ever before, and the primary challenge no longer is technology but rather the creation, validation, and maintenance of information for such websites as well as translating text-based didactics into visual and interactive tools. Medical educators can influence the design and implementation of online educational resources through creating their own websites and engaging medical students and residents in the process.

Creating a Pilot Educational Psychiatry Website: Opportunities, Barriers, and Next Steps

PubMed Central

O'Connor, Ryan; Franzen, Jamie; Snow, Caitlin; Boland, Robert; Kitts, Robert

2015-01-01

Background While medical students and residents may be utilizing websites as online learning resources, medical trainees and educators now have the opportunity to create such educational websites and digital tools on their own. However, the process and theory of building educational websites for medical education have not yet been fully explored. Objective To understand the opportunities, barriers, and process of creating a novel medical educational website. Methods We created a pilot psychiatric educational website to better understand the options, opportunities, challenges, and processes involved in the creation of a psychiatric educational website. We sought to integrate visual and interactive Web design elements to underscore the potential of such Web technology. Results A pilot website (PsychOnCall) was created to demonstrate the potential of Web technology in medical and psychiatric education. Conclusions Creating an educational website is now technically easier than ever before, and the primary challenge no longer is technology but rather the creation, validation, and maintenance of information for such websites as well as translating text-based didactics into visual and interactive tools. Medical educators can influence the design and implementation of online educational resources through creating their own websites and engaging medical students and residents in the process. PMID:27731837

Developing and Implementing an Undergraduate Finance Capstone Course for Both Onground and Online Course Delivery

ERIC Educational Resources Information Center

Wiechowski, Linda S.

2010-01-01

Capstone courses provide an opportunity to integrate several topics and to help prepare students for the real world. This paper examines the process of developing an undergraduate finance capstone course for both onground (face-to-face) and online course delivery. The process begins with the determination of the core competencies employers require…

Improving the Simplified Acquisition of Base Engineering Requirements (SABER) Delivery Order Award Process: Results of a Process Improvement Plan

DTIC Science & Technology

1991-09-01

putting all tasks directed towsrds achieving an outcome in aequence. The tasks can be viewed as steps in the process (39:2.3). Using this...improvement opportunity is investigated. A plan is developed, root causes are identified, and solutions are tested and implemented. The process is... solutions , check for actual improvement, and integrate the successful improvements into the process. ?UP 7. Check Improvement Performance. Finally, the

Biowaste biorefinery in Europe: opportunities and research & development needs.

PubMed

Fava, Fabio; Totaro, Grazia; Diels, Ludo; Reis, Maria; Duarte, Jose; Carioca, Osvaldo Beserra; Poggi-Varaldo, Héctor M; Ferreira, Bruno Sommer

2015-01-25

This review aims to explore the needs and opportunities of research & development in the field of biowaste biorefinery in Europe. Modern industry in recent years is giving its close attention on organic waste as a new precious bioresource. Specific biowaste valorisation pathways are focusing on food processing waste, being food sector the first manufacture in Europe. Anyway they need to be further tested and validated and then transferred at the larger scale. In particular, they also need to become integrated, combining biomass pretreatments and recovery of biogenic chemicals with bioconversion processes in order to obtain a large class of chemicals. This will help to (a) use the whole biowaste, by avoiding producing residues and providing to the approach the required environmental sustainability, and (b) producing different biobased products that enter different markets, to get the possible economical sustainability of the whole biorefinery. However, the costs of the developed integrated processes might be high, mostly for the fact that the industry dealing with such issues is still underdeveloped and therefore dominated by high processing costs. Such costs can be significantly reduced by intensifying research & development on process integration and intensification. The low or no cost of starting material along with the environmental benefits coming from the concomitant biowaste disposal would offset the high capital costs for initiating such a biorefinery. As long as the oil prices tend to increase (and they will) this strategy will become even more attractive. Copyright © 2013 Elsevier B.V. All rights reserved.

Examining Literacy Teachers' Perceptions of the Use of VoiceThread in an Elementary, Middle School, and a High School Classroom for Enhancing Instructional Goals

ERIC Educational Resources Information Center

Stover, Katie; Kissel, Brian; Wood, Karen; Putman, Michael

2015-01-01

In today's digital age, Web 2.0 tools such as VoiceThread allow users to integrate images, voices, and responses within one digital platform, providing students with the opportunity to add another layer of meaning to their texts. We conducted this research to expand our understanding of the processes necessary for integrating digital tools into…

The Quantum Leap in Special Education: New Information and Communication Technologies. Their Impact upon Educational Opportunities for Disabled People, Focussing on How Integration in the Ordinary Educational System Can Be Facilitated. Draft Document.

ERIC Educational Resources Information Center

Kristiansen, Rolf

This paper suggests means of merging educational ideas with new information and communication technologies to aid individuals with disabilities. New technologies discussed include microtechnology and integrated circuits, high speed processing and retrieval of information, and light-weight equipment, among others. New technologies can be used as…

Synergistic Information Processing Encrypts Strategic Reasoning in Poker.

PubMed

Frey, Seth; Albino, Dominic K; Williams, Paul L

2018-06-14

There is a tendency in decision-making research to treat uncertainty only as a problem to be overcome. But it is also a feature that can be leveraged, particularly in social interaction. Comparing the behavior of profitable and unprofitable poker players, we reveal a strategic use of information processing that keeps decision makers unpredictable. To win at poker, a player must exploit public signals from others. But using public inputs makes it easier for an observer to reconstruct that player's strategy and predict his or her behavior. How should players trade off between exploiting profitable opportunities and remaining unexploitable themselves? Using a recent multivariate approach to information theoretic data analysis and 1.75 million hands of online two-player No-Limit Texas Hold'em, we find that the important difference between winning and losing players is not in the amount of information they process, but how they process it. In particular, winning players are better at integrative information processing-creating new information from the interaction between their cards and their opponents' signals. We argue that integrative information processing does not just produce better decisions, it makes decision-making harder for others to reverse engineer, as an expert poker player's cards act like the private key in public-key cryptography. Poker players encrypt their reasoning with the way they process information. The encryption function of integrative information processing makes it possible for players to exploit others while remaining unexploitable. By recognizing the act of information processing as a strategic behavior in its own right, we offer a detailed account of how experts use endemic uncertainty to conceal their intentions in high-stakes competitive environments, and we highlight new opportunities between cognitive science, information theory, and game theory. Copyright © 2018 Cognitive Science Society, Inc.

Integrated air revitalization system for Space Station

NASA Technical Reports Server (NTRS)

Boyda, R. B.; Miller, C. W.; Schwartz, M. R.

1986-01-01

Fifty-one distinct functions are encompassed by the Space Station's Environmental Control and Life Support System; one exception to this noninteractivity of functions is the regenerative air revitalization system that removes and reduces CO2 and generates O2. The integration of these interdependent functions, and of humidity control, into a single system furnishes opportunities for process simplification as well as for power, weight and volume requirement reductions by comparison with discrete subsystems. Attention is presently given to a system which quantifies these integration-related savings and identifies additional advantages that accrue to this integrating design method.

Identity-Based Motivation: Constraints and Opportunities in Consumer Research.

PubMed

Shavitt, Sharon; Torelli, Carlos J; Wong, Jimmy

2009-07-01

This commentary underscores the integrative nature of the identity-based motivation model (Oyserman, 2009). We situate the model within existing literatures in psychology and consumer behavior, and illustrate its novel elements with research examples. Special attention is devoted to, 1) how product- and brand-based affordances constrain identity-based motivation processes and, 2) the mindsets and action tendencies that can be triggered by specific cultural identities in pursuit of consumer goals. Future opportunities are suggested for researching the antecedents of product meanings and relevant identities.

Integrating utilization-focused evaluation with business process modeling for clinical research improvement.

PubMed

Kagan, Jonathan M; Rosas, Scott; Trochim, William M K

2010-10-01

New discoveries in basic science are creating extraordinary opportunities to design novel biomedical preventions and therapeutics for human disease. But the clinical evaluation of these new interventions is, in many instances, being hindered by a variety of legal, regulatory, policy and operational factors, few of which enhance research quality, the safety of study participants or research ethics. With the goal of helping increase the efficiency and effectiveness of clinical research, we have examined how the integration of utilization-focused evaluation with elements of business process modeling can reveal opportunities for systematic improvements in clinical research. Using data from the NIH global HIV/AIDS clinical trials networks, we analyzed the absolute and relative times required to traverse defined phases associated with specific activities within the clinical protocol lifecycle. Using simple median duration and Kaplan-Meyer survival analysis, we show how such time-based analyses can provide a rationale for the prioritization of research process analysis and re-engineering, as well as a means for statistically assessing the impact of policy modifications, resource utilization, re-engineered processes and best practices. Successfully applied, this approach can help researchers be more efficient in capitalizing on new science to speed the development of improved interventions for human disease.

Discovery informatics in biological and biomedical sciences: research challenges and opportunities.

PubMed

Honavar, Vasant

2015-01-01

New discoveries in biological, biomedical and health sciences are increasingly being driven by our ability to acquire, share, integrate and analyze, and construct and simulate predictive models of biological systems. While much attention has focused on automating routine aspects of management and analysis of "big data", realizing the full potential of "big data" to accelerate discovery calls for automating many other aspects of the scientific process that have so far largely resisted automation: identifying gaps in the current state of knowledge; generating and prioritizing questions; designing studies; designing, prioritizing, planning, and executing experiments; interpreting results; forming hypotheses; drawing conclusions; replicating studies; validating claims; documenting studies; communicating results; reviewing results; and integrating results into the larger body of knowledge in a discipline. Against this background, the PSB workshop on Discovery Informatics in Biological and Biomedical Sciences explores the opportunities and challenges of automating discovery or assisting humans in discovery through advances (i) Understanding, formalization, and information processing accounts of, the entire scientific process; (ii) Design, development, and evaluation of the computational artifacts (representations, processes) that embody such understanding; and (iii) Application of the resulting artifacts and systems to advance science (by augmenting individual or collective human efforts, or by fully automating science).

Sustainability in health care by allocating resources effectively (SHARE) 4: exploring opportunities and methods for consumer engagement in resource allocation in a local healthcare setting.

PubMed

Harris, Claire; Ko, Henry; Waller, Cara; Sloss, Pamela; Williams, Pamela

2017-05-05

This is the fourth in a series of papers reporting a program of Sustainability in Health care by Allocating Resources Effectively (SHARE) in a local healthcare setting. Healthcare decision-makers have sought to improve the effectiveness and efficiency of services through removal or restriction of practices that are unsafe or of little benefit, often referred to as 'disinvestment'. A systematic, integrated, evidence-based program for disinvestment was being established within a large Australian health service network. Consumer engagement was acknowledged as integral to this process. This paper reports the process of developing a model to integrate consumer views and preferences into an organisation-wide approach to resource allocation. A literature search was conducted and interviews and workshops were undertaken with health service consumers and staff. Findings were drafted into a model for consumer engagement in resource allocation which was workshopped and refined. Although consumer engagement is increasingly becoming a requirement of publicly-funded health services and documented in standards and policies, participation in organisational decision-making is not widespread. Several consistent messages for consumer engagement in this context emerged from the literature and consumer responses. Opportunities, settings and activities for consumer engagement through communication, consultation and participation were identified within the resource allocation process. Sources of information regarding consumer values and perspectives in publications and locally-collected data, and methods to use them in health service decision-making, were identified. A model bringing these elements together was developed. The proposed model presents potential opportunities and activities for consumer engagement in the context of resource allocation.

Integrated Healthcare Delivery: A Qualitative Research Approach to Identifying and Harmonizing Perspectives of Integrated Neglected Tropical Disease Programs

PubMed Central

Jacobson, Julie; Mosher, Aryc W.; Walson, Judd L.

2016-01-01

Background While some evidence supports the beneficial effects of integrating neglected tropical disease (NTD) programs to optimize coverage and reduce costs, there is minimal information regarding when or how to effectively operationalize program integration. The lack of systematic analyses of integration experiences and of integration processes may act as an impediment to achieving more effective NTD programming. We aimed to learn about the experiences of NTD stakeholders and their perceptions of integration. Methodology We evaluated differences in the definitions, roles, perceived effectiveness, and implementation experiences of integrated NTD programs among a variety of NTD stakeholder groups, including multilateral organizations, funding partners, implementation partners, national Ministry of Health (MOH) teams, district MOH teams, volunteer rural health workers, and community members participating in NTD campaigns. Semi-structured key informant interviews were conducted. Coding of themes involved a mix of applying in-vivo open coding and a priori thematic coding from a start list. Findings In total, 41 interviews were conducted. Salient themes varied by stakeholder, however dominant themes on integration included: significant variations in definitions, differential effectiveness of specific integrated NTD activities, community member perceptions of NTD programs, the influence of funders, perceived facilitators, perceived barriers, and the effects of integration on health system strength. In general, stakeholder groups provided unique perspectives, rather than contrarian points of view, on the same topics. The stakeholders identified more advantages to integration than disadvantages, however there are a number of both unique facilitators and challenges to integration from the perspective of each stakeholder group. Conclusions Qualitative data suggest several structural, process, and technical opportunities that could be addressed to promote more effective and efficient integrated NTD elimination programs. We highlight a set of ten recommendations that may address stakeholder concerns and perceptions regarding these key opportunities. For example, public health stakeholders should embrace a broader perspective of community-based health needs, including and beyond NTDs, and available platforms for addressing those needs. PMID:27776127

Exploring Challenges and Opportunities of Coproduction: USDA Climate Hub Efforts to Integrate Coproduction with Applied Research and Decision Support Tool Development in the Northwest

NASA Astrophysics Data System (ADS)

Roesch-McNally, G.; Prendeville, H. R.

2017-12-01

A lack of coproduction, the joint production of new technologies or knowledge among technical experts and other groups, is arguably one of the reasons why much scientific information and resulting decision support systems are not very usable. Increasingly, public agencies and academic institutions are emphasizing the importance of coproduction of scientific knowledge and decision support systems in order to facilitate greater engagement between the scientific community and key stakeholder groups. Coproduction has been embraced as a way for the scientific community to develop actionable scientific information that will assist end users in solving real-world problems. Increasing the level of engagement and stakeholder buy-in to the scientific process is increasingly necessary, particularly in the context of growing politicization of science and the scientific process. Coproduction can be an effective way to build trust and can build-on and integrate local and traditional knowledge. Employing coproduction strategies may enable the development of more relevant and useful information and decision support tools that address stakeholder challenges at relevant scales. The USDA Northwest Climate Hub has increasingly sought ways to integrate coproduction in the development of both applied research projects and the development of decision support systems. Integrating coproduction, however, within existing institutions is not always simple, given that coproduction is often more focused on process than products and products are, for better or worse, often the primary focus of applied research and tool development projects. The USDA Northwest Climate Hub sought to integrate coproduction into our FY2017 call for proposal process. As a result we have a set of proposals and fledgling projects that fall along the engagement continuum (see Figure 1- attached). We will share the challenges and opportunities that emerged from this purposeful integration of coproduction into the work that we prioritized for funding. This effort highlights strategies for how federal agencies might consider how and whether to codify coproduction tenets into their collaborations and agenda setting.

Managing for Innovation in the Age of Information Technology.

ERIC Educational Resources Information Center

Downes, Robin N.

1987-01-01

Discusses the need for innovative management techniques if integrated library systems are to be implemented successfully, as well as the opportunity the installation process provides to reexamine the organizational structure and objectives of the library and to introduce a creative organizational environment. (CLB)

Computerized Manufacturing Automation. Employment, Education, and the Workplace. Summary.

ERIC Educational Resources Information Center

Congress of the U.S., Washington, DC. Office of Technology Assessment.

The application of programmable automation (PA) offers new opportunities to enhance and streamline manufacturing processes. Five PA technologies are examined in this report: computer-aided design, robots, numerically controlled machine tools, flexible manufacturing systems, and computer-integrated manufacturing. Each technology is in a relatively…

Implementing Peer Evaluation of Clinical Teaching

ERIC Educational Resources Information Center

Laske, Rita Ann

2013-01-01

Clinical education provides the nursing student opportunities to learn the practice of nursing. In the clinical setting, the nursing student applies classroom knowledge to the real patient care situation. The clinical instructor facilitates this important process by assisting students to integrate knowledge into their practice, improve their…

Strategic HRD Practices as Key Factors in Organizational Learning

ERIC Educational Resources Information Center

Tseng, Chien-Chi; McLean, Gary N.

2007-01-01

Relationships between strategic HRD practices and organizational learning were explored through a literature review. Organizations that learn and develop their SHRD practices have more opportunities to obtain and integrate the nine SHRD outcomes in the learning process: organizational missions and goals, top management leadership, environmental…

Developing an Understanding of Ions in Junior Secondary School Chemistry

ERIC Educational Resources Information Center

Waldrip, Bruce; Prain, Vaughan

2012-01-01

There is growing research interest in the challenges and opportunities learners face in representing scientific understandings, processes and reasoning. These challenges include integrating verbal, visual and mathematical modes in science discourse to make strong conceptual links between representations and classroom experiences. Our paper reports…

Metal Electrodeposition on an Integrated, Screen-Printed Electrode Assembly

ERIC Educational Resources Information Center

Chyan, Yieu; Chyan, Oliver

2008-01-01

In this lab experiment, screen-printed electrode strips are used to illustrate the essential concepts of electrochemistry, giving students an opportunity to explore metal electrodeposition processes. In the past, metal electrodeposition experiments were seldom included in general chemistry labs because of the difficulty of maintaining separate…

Nurse Satisfaction With Opportunities to Engage in Research.

PubMed

Hagan, Joseph

2018-02-01

Nurses should be able to participate in research and integrate evidence from research into practice; however, studies investigating factors related to nurse satisfaction with opportunities to engage in research are lacking. A questionnaire was distributed to nurses employed at two sites: a hospital and a nursing school. Only 16% of nurses reported being satisfied with opportunities to engage in research. In multivariate analysis, degree of belief that resources are a barrier to research was inversely proportional to satisfaction with nursing research opportunities (adjusted odds ratio = 0.13, p < .001), whereas perception that personal relevance is a barrier to research was associated with increased satisfaction (adjusted odds ratio = 2.38, p < .001). Satisfaction with opportunities to engage in research is low. Incentivizing nursing research and providing protected research time, training and education, and mentors to guide nurses through the research process could be effective strategies for increasing satisfaction and research productivity, thereby strengthening evidence-based practice.

Evolving software reengineering technology for the emerging innovative-competitive era

NASA Technical Reports Server (NTRS)

Hwang, Phillip Q.; Lock, Evan; Prywes, Noah

1994-01-01

This paper reports on a multi-tool commercial/military environment combining software Domain Analysis techniques with Reusable Software and Reengineering of Legacy Software. It is based on the development of a military version for the Department of Defense (DOD). The integrated tools in the military version are: Software Specification Assistant (SSA) and Software Reengineering Environment (SRE), developed by Computer Command and Control Company (CCCC) for Naval Surface Warfare Center (NSWC) and Joint Logistics Commanders (JLC), and the Advanced Research Project Agency (ARPA) STARS Software Engineering Environment (SEE) developed by Boeing for NAVAIR PMA 205. The paper describes transitioning these integrated tools to commercial use. There is a critical need for the transition for the following reasons: First, to date, 70 percent of programmers' time is applied to software maintenance. The work of these users has not been facilitated by existing tools. The addition of Software Reengineering will also facilitate software maintenance and upgrading. In fact, the integrated tools will support the entire software life cycle. Second, the integrated tools are essential to Business Process Reengineering, which seeks radical process innovations to achieve breakthrough results. Done well, process reengineering delivers extraordinary gains in process speed, productivity and profitability. Most importantly, it discovers new opportunities for products and services in collaboration with other organizations. Legacy computer software must be changed rapidly to support innovative business processes. The integrated tools will provide commercial organizations important competitive advantages. This, in turn, will increase employment by creating new business opportunities. Third, the integrated system will produce much higher quality software than use of the tools separately. The reason for this is that producing or upgrading software requires keen understanding of extremely complex applications which is facilitated by the integrated tools. The radical savings in the time and cost associated with software, due to use of CASE tools that support combined Reuse of Software and Reengineering of Legacy Code, will add an important impetus to improving the automation of enterprises. This will be reflected in continuing operations, as well as in innovating new business processes. The proposed multi-tool software development is based on state of the art technology, which will be further advanced through the use of open systems for adding new tools and experience in their use.

Integration process of fermentation and liquid biphasic flotation for lipase separation from Burkholderia cepacia.

PubMed

Sankaran, Revathy; Show, Pau Loke; Lee, Sze Ying; Yap, Yee Jiun; Ling, Tau Chuan

2018-02-01

Liquid Biphasic Flotation (LBF) is an advanced recovery method that has been effectively applied for biomolecules extraction. The objective of this investigation is to incorporate the fermentation and extraction process of lipase from Burkholderia cepacia using flotation system. Initial study was conducted to compare the performance of bacteria growth and lipase production using flotation and shaker system. From the results obtained, bacteria shows quicker growth and high lipase yield via flotation system. Integration process for lipase separation was investigated and the result showed high efficiency reaching 92.29% and yield of 95.73%. Upscaling of the flotation system exhibited consistent result with the lab-scale which are 89.53% efficiency and 93.82% yield. The combination of upstream and downstream processes in a single system enables the acceleration of product formation, improves the product yield and facilitates downstream processing. This integration system demonstrated its potential for biomolecules fermentation and separation that possibly open new opportunities for industrial production. Copyright © 2017 Elsevier Ltd. All rights reserved.

Strategic Review Process for an Accountable Care Organization and Emerging Accountable Care Best Practices.

PubMed

Conway, Sarah J; Himmelrich, Sarah; Feeser, Scott A; Flynn, John A; Kravet, Steven J; Bailey, Jennifer; Hebert, Lindsay C; Donovan, Susan H; Kachur, Sarah G; Brown, Patricia M C; Baumgartner, William A; Berkowitz, Scott A

2018-02-02

Accountable Care Organizations (ACOs), like other care entities, must be strategic about which initiatives they support in the quest for higher value. This article reviews the current strategic planning process for the Johns Hopkins Medicine Alliance for Patients (JMAP), a Medicare Shared Savings Program Track 1 ACO. It reviews the 3 focus areas for the 2017 strategic review process - (1) optimizing care coordination for complex, at-risk patients, (2) post-acute care, and (3) specialty care integration - reviewing cost savings and quality improvement opportunities, associated best practices from the literature, and opportunities to leverage and advance existing ACO and health system efforts in each area. It then reviews the ultimate selection of priorities for the coming year and early thoughts on implementation. After the robust review process, key stakeholders voted to select interventions targeted at care coordination, post-acute care, and specialty integration including Part B drug and imaging costs. The interventions selected incorporate a mixture of enhancing current ACO initiatives, working collaboratively and synergistically on other health system initiatives, and taking on new projects deemed targeted, cost-effective, and manageable in scope. The annual strategic review has been an essential and iterative process based on performance data and informed by the collective experience of other organizations. The process allows for an evidence-based strategic plan for the ACO in pursuit of the best care for patients.

Nanocuration Workflows: Establishing best practices for identifying, inputting, and sharing data to inform decisions on nanomaterials

EPA Science Inventory

There is a critical opportunity in the field of nanoscience to compare and integrate information across diverse fields of study through informatics (i.e., nanoinformatics). This paper is one in a series of articles on the data curation process in nanoinformatics (nanocuration). O...

Quality Assurance, Open and Distance Learning, and Australian Universities

ERIC Educational Resources Information Center

Reid, Ian C.

2005-01-01

Open and distance education has integrated quality assurance processes since its inception. Recently, the increased use of distance teaching systems, technologies, and pedagogies by universities without a distance education heritage has enabled them to provide flexible learning opportunities. They have done this in addition to, or instead of,…

An organismal view of dendrochronology

Treesearch

Kevin T. Smith

2008-01-01

An organism is the most basic unit of independent life. The tree-ring record is defined by organismal processes. Dendrochronology contributes to investigations far removed from organismal biology, e.g., archeology, climatology, disturbance ecology, etc. The increasing integration of dendrochronology into a diverse research community suggests an opportunity for a brief...

Focus on Methodology: Salivary Bioscience and Research on Adolescence: An Integrated Perspective

ERIC Educational Resources Information Center

Granger, Douglas A.; Fortunato, Christine K.; Beltzer, Emilie K.; Virag, Marta; Bright, Melissa A.; Out, Dorothee

2012-01-01

The characterization of the salivary proteome and advances in biotechnology create an opportunity for developmental scientists to measure multi-level components of biological systems in oral fluids and identify relationships with developmental processes and behavioral and social forces. The implications for developmental science are profound…

Frontiers in Chemical Engineering. Research Needs and Opportunities.

ERIC Educational Resources Information Center

National Academy of Sciences - National Research Council, Washington, DC. Commission on Physical Sciences, Mathematics, and Resources.

Chemical engineers play a key role in industries such as petroleum, food, artificial fibers, petrochemicals, plastics and many others. They are needed to tailor manufacturing technology to the requirements of products and to integrate product and process design. This report discusses how chemical engineers are continuing to address technological…

Designing a Culturally Sensitive Wiki Space for Developing Chinese Students' Media Literacy

ERIC Educational Resources Information Center

Mezentceva, Daria

2014-01-01

Due to technological development and intensification of integration processes all over the world, people from different cultural backgrounds have more opportunities to maintain academic and professional cooperation. To make this cooperation more effective, it is important to take into consideration diverse ethnic values and their influence on…

University Students' Perceptions of Electronic Rubric-Based Assessment

ERIC Educational Resources Information Center

Raposo-Rivas, Manuela; Gallego-Arrufat, María-Jesús

2016-01-01

Integrating technology into assessment processes in university contexts can change educational practices, in some cases by fostering self-regulated learning and in others by enabling more interactivity and participation among users. In this paper, we examine the opportunity to use electronic rubrics (erubrics) to assess learning. We report a…

Teaching Complex Concepts in the Geosciences by Integrating Analytical Reasoning with GIS

ERIC Educational Resources Information Center

Houser, Chris; Bishop, Michael P.; Lemmons, Kelly

2017-01-01

Conceptual models have long served as a means for physical geographers to organize their understanding of feedback mechanisms and complex systems. Analytical reasoning provides undergraduate students with an opportunity to develop conceptual models based upon their understanding of surface processes and environmental conditions. This study…

Mission Engineering of a Rapid Cycle Spacecraft Logistics Fleet

NASA Technical Reports Server (NTRS)

Holladay, Jon; McClendon, Randy (Technical Monitor)

2002-01-01

The requirement for logistics re-supply of the International Space Station has provided a unique opportunity for engineering the implementation of NASA's first dedicated pressurized logistics carrier fleet. The NASA fleet is comprised of three Multi-Purpose Logistics Modules (MPLM) provided to NASA by the Italian Space Agency in return for operations time aboard the International Space Station. Marshall Space Flight Center was responsible for oversight of the hardware development from preliminary design through acceptance of the third flight unit, and currently manages the flight hardware sustaining engineering and mission engineering activities. The actual MPLM Mission began prior to NASA acceptance of the first flight unit in 1999 and will continue until the de-commission of the International Space Station that is planned for 20xx. Mission engineering of the MPLM program requires a broad focus on three distinct yet inter-related operations processes: pre-flight, flight operations, and post-flight turn-around. Within each primary area exist several complex subsets of distinct and inter-related activities. Pre-flight processing includes the evaluation of carrier hardware readiness for space flight. This includes integration of payload into the carrier, integration of the carrier into the launch vehicle, and integration of the carrier onto the orbital platform. Flight operations include the actual carrier operations during flight and any required real-time ground support. Post-flight processing includes de-integration of the carrier hardware from the launch vehicle, de-integration of the payload, and preparation for returning the carrier to pre-flight staging. Typical space operations are engineered around the requirements and objectives of a dedicated mission on a dedicated operational platform (i.e. Launch or Orbiting Vehicle). The MPLM, however, has expanded this envelope by requiring operations with both vehicles during flight as well as pre-launch and post-landing operations. These unique requirements combined with a success-oriented schedule of four flights within a ten-month period have provided numerous opportunities for understanding and improving operations processes. Furthermore, it has increased the knowledge base of future Payload Carrier and Launch Vehicle hardware and requirement developments. Discussion of the process flows and target areas for process improvement are provided in the subject paper. Special emphasis is also placed on supplying guidelines for hardware development. The combination of process knowledge and hardware development knowledge will provide a comprehensive overview for future vehicle developments as related to integration and transportation of payloads.

Modelling nutritional mutualisms: challenges and opportunities for data integration.

PubMed

Clark, Teresa J; Friel, Colleen A; Grman, Emily; Shachar-Hill, Yair; Friesen, Maren L

2017-09-01

Nutritional mutualisms are ancient, widespread, and profoundly influential in biological communities and ecosystems. Although much is known about these interactions, comprehensive answers to fundamental questions, such as how resource availability and structured interactions influence mutualism persistence, are still lacking. Mathematical modelling of nutritional mutualisms has great potential to facilitate the search for comprehensive answers to these and other fundamental questions by connecting the physiological and genomic underpinnings of mutualisms with ecological and evolutionary processes. In particular, when integrated with empirical data, models enable understanding of underlying mechanisms and generalisation of principles beyond the particulars of a given system. Here, we demonstrate how mathematical models can be integrated with data to address questions of mutualism persistence at four biological scales: cell, individual, population, and community. We highlight select studies where data has been or could be integrated with models to either inform model structure or test model predictions. We also point out opportunities to increase model rigour through tighter integration with data, and describe areas in which data is urgently needed. We focus on plant-microbe systems, for which a wealth of empirical data is available, but the principles and approaches can be generally applied to any nutritional mutualism. © 2017 John Wiley & Sons Ltd/CNRS.

Maximizing information from space data resources: a case for expanding integration across research disciplines.

PubMed

Goswami, Nandu; Batzel, Jerry J; Clément, Gilles; Stein, T Peter; Hargens, Alan R; Sharp, M Keith; Blaber, Andrew P; Roma, Peter G; Hinghofer-Szalkay, Helmut G

2013-07-01

Regulatory systems are affected in space by exposure to weightlessness, high-energy radiation or other spaceflight-induced changes. The impact of spaceflight occurs across multiple scales and systems. Exploring such interactions and interdependencies via an integrative approach provides new opportunities for elucidating these complex responses. This paper argues the case for increased emphasis on integration, systematically archiving, and the coordination of past, present and future space and ground-based analogue experiments. We also discuss possible mechanisms for such integration across disciplines and missions. This article then introduces several discipline-specific reviews that show how such integration can be implemented. Areas explored include: adaptation of the central nervous system to space; cerebral autoregulation and weightlessness; modelling of the cardiovascular system in space exploration; human metabolic response to spaceflight; and exercise, artificial gravity, and physiologic countermeasures for spaceflight. In summary, spaceflight physiology research needs a conceptual framework that extends problem solving beyond disciplinary barriers. Administrative commitment and a high degree of cooperation among investigators are needed to further such a process. Well-designed interdisciplinary research can expand opportunities for broad interpretation of results across multiple physiological systems, which may have applications on Earth.

Multidisciplinary management--an opportunity for service integration.

PubMed

Cameron, M

1997-01-01

The management team of the future will enter an environment requiring facilitation, participation, clinical, and empowerment skills. Those individuals who possess a clinical orientation as well as business expertise will be sought to manage multidisciplinary units. The rapid changes in the health-care environment have forced organizations to restructure their operations. To achieve quality care, customer satisfaction, cost-effectiveness, and efficiency, service integration across the organization will be required. As we approach the 21st century, this standard will evolve until "all levels are managing patient care." Some of the restructuring trends occurring in the health-care industry have been collaboration service integration, management consolidation, and job elimination. The emphasis for the multidisciplinary manager of the future will include integrating the professional and clinical services, managing information, building community partnerships, promoting physician collaboration, and managing the change process. A model organization in the next century will move toward a people-oriented system with inclusion and empowerment initiatives. Service integration will affect all organizations, but the disciplines within the Clinical Support System will be the most affected. Future opportunities of leadership will exist for pathologists, nurses, or medical technologists as the professional silos of managers and clinicians continue to crumble.

Identity-Based Motivation: Constraints and Opportunities in Consumer Research

PubMed Central

Shavitt, Sharon; Torelli, Carlos J.; Wong, Jimmy

2009-01-01

This commentary underscores the integrative nature of the identity-based motivation model (Oyserman, 2009). We situate the model within existing literatures in psychology and consumer behavior, and illustrate its novel elements with research examples. Special attention is devoted to, 1) how product- and brand-based affordances constrain identity-based motivation processes and, 2) the mindsets and action tendencies that can be triggered by specific cultural identities in pursuit of consumer goals. Future opportunities are suggested for researching the antecedents of product meanings and relevant identities. PMID:20161045

Benefits to blood banks of a sales and operations planning process.

PubMed

Keal, Donald A; Hebert, Phil

2010-12-01

A formal sales and operations planning (S&OP) process is a decision making and communication process that balances supply and demand while integrating all business operational components with customer-focused business plans that links high level strategic plans to day-to-day operations. Furthermore, S&OP can assist in managing change across the organization as it provides the opportunity to be proactive in the face of problems and opportunities while establishing a plan for everyone to follow. Some of the key outcomes from a robust S&OP process in blood banking would include: higher customer satisfaction (donors and health care providers), balanced inventory across product lines and customers, more stable production rates and higher productivity, more cooperation across the entire operation, and timely updates to the business plan resulting in better forecasting and fewer surprises that negatively impact the bottom line. © 2010 American Association of Blood Banks.

The changing paradigm in surgery is system integration: How do we respond?

PubMed

Zenilman, Michael E; Freischlag, Julie-Ann

2017-12-08

With expansion of health care systems across the country, close relationships need to be developed between academic medical centers and their affiliated community hospitals. This creates opportunity to integrate surgical programs across different hospitals. Herein we describe a model of surgical integration at the system level of five large hospitals. We discuss utilizing advantages that both the academic and community hospital bring to the model. A close relationship between an interdisciplinary team, which includes the academic surgical chair, a regional director liaison who was embedded in the community, individual hospital leadership, and practice plan leaders was created. Three pillars as a foundation to success were physician leadership, the use of system infrastructure and development of new processes. This resulted in development of trust, leading to successful recruitments, models of employment and expansion into novel areas of patient safety. Once created, new opportunities for programming for surgical safety across the health care were identified. Copyright © 2017 Elsevier Inc. All rights reserved.

The power of theater to promote individual recovery and social change.

PubMed

Faigin, David A; Stein, Catherine H

2010-03-01

Although theatrical activities are used in a variety of therapeutic settings, little attention has been paid to the ways that theater can enhance the recovery process and community integration for people living with psychiatric disabilities. Community-based theater involving people with psychiatric disabilities offers unique opportunities for personal growth, social connection, and advocacy efforts. This Open Forum posits that theater has the power to both facilitate individual recovery and improve the social conditions of people living with mental illness. Critical elements of theatrical activities that relate to processes of recovery and community integration are examined. Implications for future research and program development are discussed.

Challenges and opportunities in social neuroscience

PubMed Central

Cacioppo, John T.; Decety, Jean

2010-01-01

Social species are so characterized because they form organizations that extend beyond the individual. The goal of social neuroscience is to investigate the biological mechanisms that underlie these social structures, processes, and behavior and the influences between social and neural structures and processes. Such an endeavor is challenging because it necessitates the integration of multiple levels. Mapping across systems and levels (from genome to social groups and cultures) requires interdisciplinary expertise, comparative studies, innovative methods, and integrative conceptual analysis. Examples of how social neuroscience is contributing to our understanding of the functions of the brain and nervous system are described, and societal implications of social neuroscience are considered. PMID:21251011

Opportunity integrated assessment facilitating critical thinking and science process skills measurement on acid base matter

NASA Astrophysics Data System (ADS)

Sari, Anggi Ristiyana Puspita; Suyanta, LFX, Endang Widjajanti; Rohaeti, Eli

2017-05-01

Recognizing the importance of the development of critical thinking and science process skills, the instrument should give attention to the characteristics of chemistry. Therefore, constructing an accurate instrument for measuring those skills is important. However, the integrated instrument assessment is limited in number. The purpose of this study is to validate an integrated assessment instrument for measuring students' critical thinking and science process skills on acid base matter. The development model of the test instrument adapted McIntire model. The sample consisted of 392 second grade high school students in the academic year of 2015/2016 in Yogyakarta. Exploratory Factor Analysis (EFA) was conducted to explore construct validity, whereas content validity was substantiated by Aiken's formula. The result shows that the KMO test is 0.714 which indicates sufficient items for each factor and the Bartlett test is significant (a significance value of less than 0.05). Furthermore, content validity coefficient which is based on 8 experts is obtained at 0.85. The findings support the integrated assessment instrument to measure critical thinking and science process skills on acid base matter.

Teaming up to crack innovation and enterprise integration.

PubMed

Cash, James I; Earl, Michael J; Morison, Robert

2008-11-01

In the continuing quest for business growth, many CEOs are turning to their CIOs and IT organizations because technology is essential to two compelling sources of growth: innovation and integration. Innovation, of course, is doing new things that customers ultimately appreciate and value--not only developing new generations of products, services, channels, and customer experience but also conceiving new business processes and models. Integration is making the multiple units, functions, and sites of large organizations work together to increase capacity, improve performance, lower cost structure, and discover opportunities for improvement that don't appear until you look across functions.

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

This intern report consists of the workshop handbook for the Comprehensive Environmental and Natural Resource Management Planning workshop presented by the Council of Energy Resource Tribes. The workshop objectives were to foster and awareness of integrated resource management rationale; present the fundamental elements of an integrated approach; explain what distinguishes this approach from mainstream strategies; discuss how worldview and philosophy shape action and policy; present ways in which philosophical dexterity promotes effective management; and identify opportunities to engage and participate in integrated management. Resource articles presented at the meeting have been removed for separate processing for inclusion on the datamore » base.« less

Integrating human health into environmental impact assessment: an unrealized opportunity for environmental health and justice.

PubMed

Bhatia, Rajiv; Wernham, Aaron

2008-08-01

The National Environmental Policy Act and related state laws require many public agencies to analyze and disclose potentially significant environmental effects of agency actions, including effects on human health. In this paper we review the purpose and procedures of environmental impact assessment (EIA), existing regulatory requirements for health effects analysis, and potential barriers to and opportunities for improving integration of human health concerns within the EIA process. We use statutes, regulations, guidelines, court opinions, and empirical research on EIA along with recent case examples of integrated health impact assessment (HIA)/EIA at both the state and federal level. We extract lessons and recommendations for integrated HIA/EIA practice from both existing practices as well as case studies. The case studies demonstrate the adequacy, scope, and power of existing statutory requirements for health analysis within EIA. The following support the success of integrated HIA/EIA: a proponent recognizing EIA as an available regulatory strategy for public health; the openness of the agency conducting the EIA; involvement of public health institutions; and complementary objectives among community stakeholders and health practitioners. We recommend greater collaboration among institutions responsible for EIA, public health institutions, and affected stakeholders along with guidance, resources, and training for integrated HIA/EIA practice.

Integrating Human Health into Environmental Impact Assessment: An Unrealized Opportunity for Environmental Health and Justice

PubMed Central

Bhatia, Rajiv; Wernham, Aaron

2008-01-01

Objectives The National Environmental Policy Act and related state laws require many public agencies to analyze and disclose potentially significant environmental effects of agency actions, including effects on human health. In this paper we review the purpose and procedures of environmental impact assessment (EIA), existing regulatory requirements for health effects analysis, and potential barriers to and opportunities for improving integration of human health concerns within the EIA process. Data sources We use statutes, regulations, guidelines, court opinions, and empirical research on EIA along with recent case examples of integrated health impact assessment (HIA)/EIA at both the state and federal level. Data synthesis We extract lessons and recommendations for integrated HIA/EIA practice from both existing practices as well as case studies. Conclusions The case studies demonstrate the adequacy, scope, and power of existing statutory requirements for health analysis within EIA. The following support the success of integrated HIA/EIA: a proponent recognizing EIA as an available regulatory strategy for public health; the openness of the agency conducting the EIA; involvement of public health institutions; and complementary objectives among community stakeholders and health practitioners. We recommend greater collaboration among institutions responsible for EIA, public health institutions, and affected stakeholders along with guidance, resources, and training for integrated HIA/EIA practice. PMID:18709140

Political, policy and social barriers to health system interoperability: emerging opportunities of Web 2.0 and 3.0.

PubMed

Juzwishin, Donald W M

2009-01-01

Achieving effective health informatics interoperability in a fragmented and uncoordinated health system is by definition not possible. Interoperability requires the simultaneous integration of health care processes and information across different types and levels of care (systems thinking). The fundamental argument of this paper is that information system interoperability will remain an unfulfilled hope until health reforms effectively address the governance (accountability), structural and process barriers to interoperability of health care delivery. The ascendency of Web 2.0 and 3.0, although still unproven, signals the opportunity to accelerate patients' access to health information and their health record. Policy suggestions for simultaneously advancing health system delivery and information system interoperability are posited.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Matthew R. Kumjian; Giangrande, Scott E.; Mishra, Subashree

Polarimetric radar observations increasingly are used to understand cloud microphysical processes, which is critical for improving their representation in cloud and climate models. In particular, there has been recent focus on improving representations of ice collection processes (e.g., aggregation, riming), as these influence precipitation rate, heating profiles, and ultimately cloud life cycles. However, distinguishing these processes using conventional polarimetric radar observations is difficult, as they produce similar fingerprints. This necessitates improved analysis techniques and integration of complementary data sources. Furthermore, the Midlatitude Continental Convective Clouds Experiment (MC3E) provided such an opportunity.

A liberation psychology approach to acculturative integration of migrant populations.

PubMed

García-Ramírez, Manuel; de la Mata, Manuel L; Paloma, Virginia; Hernández-Plaza, Sonia

2011-03-01

This paper describes an acculturative integration approach that stresses the contribution of liberation psychology. Immigrant integration is a challenge for receiving countries in the Western world due to the frequent asymmetrical and oppressive conditions suffered by newcomers in their new settlements. The cross-cultural perspective connects integration with psychological acculturation, emphasizing harmony between acquisitions of the new culture while maintaining cultural heritage, and creating opportunities for intergroup relationships. In turn, liberation psychology permits an understanding of the acculturative transition as an empowerment and self-construction process by which immigrants acquire a new vision of the world and of themselves, transforming both structural conditions and themselves. From this perspective we conceptualize acculturative integration as the process by which newcomers become an accepted part of the new society through a reflexive and evaluative process, changing their social references and position, rebuilding their social and personal resources, and achieving a new agency in coherence with their new challenges and goals. In this process, they acquire critical thinking about unequal conditions, gain capacities to respond to the inequalities, and take effective actions to confront them. We illustrate this process using the narratives of nine Moroccan women who are living in asymmetrical and oppressive local contexts in Andalusia, the southern-most region of Spain.

School-to-Work Risk Management.

ERIC Educational Resources Information Center

Voorheis, Greg; Meyer, Gregg; Van Houten, June

This paper examines risk and liability issues related to school to work (STW) programs. With the passage of the federal School-to-Work Opportunities Act of 1994, the distance between the school and the world of work is diminishing. The Act's requirement that students, schools, and employers become part of an integrated learning process brings the…

Developing Self-Management and Teamwork Using Digital Games in 3D Simulations

ERIC Educational Resources Information Center

Cela-Ranilla, Jose M.; Esteve-Mon, Francesc M.; Esteve-González, Vanessa; Gisbert-Cervera, Merce

2014-01-01

Emerging technologies are providing opportunities for designing new learning environments, especially environments in which students can learn by putting their skills into practice. Knowledge about the development of these experiences needs to be accumulated and processed so that they can be integrated effectively into training programmes. In this…

Online Chats: A Strategy to Enhance Learning in Large Classes

ERIC Educational Resources Information Center

Mtshali, Muntuwenkosi Abraham; Maistry, Suriamurthee Moonsamy; Govender, Desmond Wesley

2015-01-01

Online-supported teaching and learning is a technological innovation in education that integrates face-to-face teaching in plenary lectures, with an online component using a learning management system. This extends opportunities to students to interact with one another via online chats in the process of transacting their learning. There is a need…

Pursuing the Delta -- Maximizing Opportunities to Integrate Sustainability in the Funding Processes

DTIC Science & Technology

2011-03-03

that may contain safety and health hazards. This is not an all-inclusive list: a. Fire protection issues b. Toxic fumes (i.e., engine exhaust...hazards shall be reported as part of the SAR. A.6 Hazardous Materials. The contractor shall not use cadmium, hexavalent chromium , or other

Sandia National Laboratories: Careers: Life at Sandia: People and Culture

Science.gov Websites

; Culture Work-Life Balance Special Programs Students and Postdocs Benefits and Perks Hiring Process Life at -Life Balance Careers People and Culture Solar cell picture Quality people, quality work Integrity , the incredible work-life balance." View All Jobs Equal opportunity employer/Disability/Vet/GLBT

Finding Quality Information on Internet for Educational Use

ERIC Educational Resources Information Center

Khine, Myint Swe

2006-01-01

One of the major shifts in education today under the influence of information and communication technologies is that there is an increased tendency toward the use of computers and Internet. The process of ICT integration in schools reaches a considerable level of maturity and teachers and students are optimizing the learning opportunities with the…

Providing Elementary Students Equitable Access to Notebook Computers by Empowering Three School Communities in Shared Decision Making.

ERIC Educational Resources Information Center

Despot, Paula C.

This practicum was designed to provide elementary students from low-socioeconomic school communities equitable opportunities to use notebook computer technology in the communication process. A multi-dimensional staff development program was designed and conducted to integrate computer technology in the classroom. Students and their families were…

Engaging Minds in the Common Core: Integrating Standards for Student Engagement

ERIC Educational Resources Information Center

Howard, Christy

2016-01-01

With the implementation of Common Core State Standards (CCSS) many teachers continue to search for ways to engage students in the learning process while meeting the rigorous demands of the standards. Researchers suggest that by providing opportunities for higher order thinking, student choice, and creative ways to showcase knowledge, students will…

Flying beyond Gray's Anatomy: A psychologist's experience in palliative care and psycho-oncology.

PubMed

O'Brien, Casey L

2015-12-01

A clinical fellowship provides opportunities for health professionals to learn specialist skills from experienced mentors in "real-world" environments. In 2010-2011, I had the opportunity to complete a palliative care and psycho-oncology clinical fellowship in a public hospital. I found ways to integrate academic training into my practice and become a more independent psychologist. In this essay, I aim to share my experience with others and highlight key learnings and challenges I encountered. In providing psychosocial care, I learned to adapt my psychological practice to a general hospital setting, learning about the medical concerns, and life stories of my patients. I faced challenges navigating referral processes and had opportunities to strengthen my psychotherapy training. In the fellowship, I engaged in educational activities from the more familiar psychological skills to observing surgical teams at work. I also developed confidence facilitating groups and an interest in group psychological support for young adult offspring of people with cancer. I was able to engage participants with haematological cancer in qualitative research about their experiences of corticosteroid treatment. In this process, I came to understand the complexity of chemotherapy regimens. Overseeing my development were multiple supervisors, offering unique insights that I could take in and integrate with my personal practice and worldview. Throughout this process I became increasingly tuned into my own process, the impact of the work, and developed self-care routines to help disconnect from my day. I also reflected on my experiences of loss and grief and developed a deeper understanding of myself as a person. I use the metaphor of a parachuting journey to illustrate various aspects of my learning.

Building Bridges to Integrate Care (BRIDGES): Incubating Health Service Innovation across the Continuum of Care for Patients with Multiple Chronic Conditions.

PubMed

Bhattacharyya, Onil; Schull, Michael; Shojania, Kaveh; Stergiopoulos, Vicky; Naglie, Gary; Webster, Fiona; Brandao, Ricardo; Mohammed, Tamara; Christian, Jennifer; Hawker, Gillian; Wilson, Lynn; Levinson, Wendy

2016-01-01

Integrating care for people with complex needs is challenging. Indeed, evidence of solutions is mixed, and therefore, well-designed, shared evaluation approaches are needed to create cumulative learning. The Toronto-based Building Bridges to Integrate Care (BRIDGES) collaborative provided resources to refine and test nine new models linking primary, hospital and community care. It used mixed methods, a cross-project meta-evaluation and shared outcome measures. Given the range of skills required to develop effective interventions, a novel incubator was used to test and spread opportunities for system integration that included operational expertise and support for evaluation and process improvement.

A MoTe2 based light emitting diode and photodetector for silicon photonic integrated circuits

NASA Astrophysics Data System (ADS)

Bie, Ya-Qing; Heuck, M.; Grosso, G.; Furchi, M.; Cao, Y.; Zheng, J.; Navarro-Moratalla, E.; Zhou, L.; Taniguchi, T.; Watanabe, K.; Kong, J.; Englund, D.; Jarillo-Herrero, P.

A key challenge in photonics today is to address the interconnects bottleneck in high-speed computing systems. Silicon photonics has emerged as a leading architecture, partly because many components such as waveguides, interferometers and modulators, could be integrated on silicon-based processors. However, light sources and photodetectors present continued challenges. Common approaches for light source include off-chip or wafer-bonded lasers based on III-V materials, but studies show advantages for directly modulated light sources. The most advanced photodetectors in silicon photonics are based on germanium growth which increases system cost. The emerging two dimensional transition metal dichalcogenides (TMDs) offer a path for optical interconnects components that can be integrated with the CMOS processing by back-end-of-the-line processing steps. Here we demonstrate a silicon waveguide-integrated light source and photodetector based on a p-n junction of bilayer MoTe2, a TMD semiconductor with infrared band gap. The state-of-the-art fabrication technology provides new opportunities for integrated optoelectronic systems.

Rewarding safe behavior: strategies for change.

PubMed

Fell-Carlson, Deborah

2004-12-01

Effective, sustainable safety incentives are integrated into a performance management system designed to encourage long term behavior change. Effective incentive program design integrates the fundamental considerations of compensation (i.e., valence, instrumentality, expectancy, equity) with behavior change theory in the context of a strong merit based performance management system. Clear expectations are established and communicated from the time applicants apply for the position. Feedback and social recognition are leveraged and used as rewards, in addition to financial incentives built into the compensation system and offered periodically as short term incentives. Rewards are tied to specific objectives intended to influence specific behaviors. Objectives are designed to challenge employees, providing opportunities to grow and enhance their sense of belonging. Safety contests and other awareness activities are most effective when used to focus safety improvement efforts on specific behaviors or processes, for a predetermined period of time, in the context of a comprehensive safety system. Safety incentive programs designed around injury outcomes can result in unintended, and undesirable, consequences. Safety performance can be leveraged by integrating safety into corporate cultural indicators. Symbols of safety remind employees of corporate safety goals and objectives (e.g., posted safety goals and integrating safety into corporate mission and vision). Rites and ceremonies provide opportunities for social recognition and feedback and demonstrate safety is a corporate value. Feedback opportunities, rewards, and social recognition all provide content for corporate legends, those stories embellished over time, that punctuate the overall system of organizational norms, and provide examples of the organizational safety culture in action.

Small Payload Launch Integrated Testing Services (SPLITS) - SPSDL

NASA Technical Reports Server (NTRS)

Plotner, Benjamin

2013-01-01

My experience working on the Small Payload Launch Integrated Testing Services project has been both educational and rewarding. I have been given the opportunity to work on and experiment with a number of exciting projects and initiatives, each offering different challenges and opportunities for teamwork and collaboration. One of my assignments is to aid in the design and construction of a small-scale two stage rocket as part of a Rocket University initiative. My duties include programming a microcontroller to control the various sensors on the rocket as well as process and transmit data. Additionally, I am writing a graphical user interface application for the ground station that will receive the transmitted data from the rocket and display the information on screen along with a 3D rendering displaying the rocket orientation. Another project I am working on is to design and develop the avionics that will be used to control a high altitude balloon flight that will test a sensor called a Micro Dosimeter that will measure the total ionizing dose absorbed by electrical components during a flight. This includes assembling and soldering the various sensors and components, programming a microcontroller to input and process data from the Micro Dosimeter, and transmitting the data down to a ground station as well as save the data to an on-board SD card. Additionally, I am aiding in the setup and development of ITOS (Integrated Test and Operations System) capability in the SPSDL (Spaceport Processing System Development Lab).

Elements for successful sensor-based process control {Integrated Metrology}

NASA Astrophysics Data System (ADS)

Butler, Stephanie Watts

1998-11-01

Current productivity needs have stimulated development of alternative metrology, control, and equipment maintenance methods. Specifically, sensor applications provide the opportunity to increase productivity, tighten control, reduce scrap, and improve maintenance schedules and procedures. Past experience indicates a complete integrated solution must be provided for sensor-based control to be used successfully in production. In this paper, Integrated Metrology is proposed as the term for an integrated solution that will result in a successful application of sensors for process control. This paper defines and explores the perceived four elements of successful sensor applications: business needs, integration, components, and form. Based upon analysis of existing successful commercially available controllers, the necessary business factors have been determined to be strong, measurable industry-wide business needs whose solution is profitable and feasible. This paper examines why the key aspect of integration is the decision making process. A detailed discussion is provided of the components of most importance to sensor based control: decision-making methods, the 3R's of sensors, and connectivity. A metric for one of the R's (resolution) is proposed to allow focus on this important aspect of measurement. A form for these integrated components which synergistically partitions various aspects of control at the equipment and MES levels to efficiently achieve desired benefits is recommended.

Fine grained event processing on HPCs with the ATLAS Yoda system

NASA Astrophysics Data System (ADS)

Calafiura, Paolo; De, Kaushik; Guan, Wen; Maeno, Tadashi; Nilsson, Paul; Oleynik, Danila; Panitkin, Sergey; Tsulaia, Vakhtang; Van Gemmeren, Peter; Wenaus, Torre

2015-12-01

High performance computing facilities present unique challenges and opportunities for HEP event processing. The massive scale of many HPC systems means that fractionally small utilization can yield large returns in processing throughput. Parallel applications which can dynamically and efficiently fill any scheduling opportunities the resource presents benefit both the facility (maximal utilization) and the (compute-limited) science. The ATLAS Yoda system provides this capability to HEP-like event processing applications by implementing event-level processing in an MPI-based master-client model that integrates seamlessly with the more broadly scoped ATLAS Event Service. Fine grained, event level work assignments are intelligently dispatched to parallel workers to sustain full utilization on all cores, with outputs streamed off to destination object stores in near real time with similarly fine granularity, such that processing can proceed until termination with full utilization. The system offers the efficiency and scheduling flexibility of preemption without requiring the application actually support or employ check-pointing. We will present the new Yoda system, its motivations, architecture, implementation, and applications in ATLAS data processing at several US HPC centers.

Possibilities of the Integration of the Method of the Ecologically Oriented Independent Scientific Research in the Study Process

NASA Astrophysics Data System (ADS)

Grizans, Jurijs; Vanags, Janis

2010-01-01

The aim of this paper is to analyse possibilities of the integration of the method of the ecologically oriented independent scientific research in the study process. In order to achieve the set aim, the following scientific research methods were used: analysis of the conceptual guidelines for the development of environmentally oriented entrepreneurship, interpretation of the experts' evaluation of the ecologically oriented management, analysis of the results of the students' ecologically oriented independent scientific research, as well as monographic and logically constructive methods. The results of the study give an opportunity to make conclusions and to develop conceptual recommendations on how to introduce future economics and business professionals with the theoretical and practical aspects of ecologically oriented management during the study process.

Laboratory experiments in integrated circuit fabrication

NASA Technical Reports Server (NTRS)

Jenkins, Thomas J.; Kolesar, Edward S.

1993-01-01

The objectives of the experiment are fourfold: to provide practical experience implementing the fundamental processes and technology associated with the science and art of integrated circuit (IC) fabrication; to afford the opportunity for the student to apply the theory associated with IC fabrication and semiconductor device operation; to motivate the student to exercise engineering decisions associated with fabricating integrated circuits; and to complement the theory of n-channel MOS and diffused devices that are presented in the classroom by actually fabricating and testing them. Therefore, a balance between theory and practice can be realized in the education of young engineers, whose education is often criticized as lacking sufficient design and practical content.

Studies of Thermophysical Properties of Metals and Semiconductors by Containerless Processing Under Microgravity

NASA Technical Reports Server (NTRS)

Seidel, A.; Soellner, W.; Stenzel, C.

2012-01-01

Electromagnetic levitation under microgravity provides unique opportunities for the investigation of liquid metals, alloys and semiconductors, both above and below their melting temperatures, with minimized disturbances of the sample under investigation. The opportunity to perform such experiments will soon be available on the ISS with the EML payload which is currently being integrated. With its high-performance diagnostics systems EML allows to measure various physical properties such as heat capacity, enthalpy of fusion, viscosity, surface tension, thermal expansion coefficient, and electrical conductivity. In studies of nucleation and solidification phenomena the nucleation kinetics, phase selection, and solidification velocity can be determined. Advanced measurement capabilities currently being studied include the measurement and control of the residual oxygen content of the process atmosphere and a complementary inductive technique to measure thermophysical properties.

Analysis to develop a program for energy-integrated farm systems

NASA Astrophysics Data System (ADS)

Eakin, D. E.; Clark, M. A.; Inaba, L. K.; Johnson, K. I.

1981-09-01

A program to use renewable energy resources and possibly develop decentralization of energy systems for agriculture is discussed. The program's objective is determined by: (1) an analysis of the technologies that could be utilized to transform renewable farm resources to energy by the year 2000, (2) the quantity of renewable farm resources that are available, and (3) current energy-use patterns. Individual research, development, and demonstration projects are fit into a national program of energy-integrated farm systems on the basis of market need, conversion potential, technological opportunities, and acceptability. Quantification of these factors for the purpose of establishing program guidelines is conducted using the following four precepts: (1) market need is identified by current use of energy for agricultural production; (2) conversion potential is determined by the availability of renewable resources; and (3) technological opportunities are determined by the state-of-the-art methods, techniques, and processes that can convert renewable resources into farm energy.

GeoFrame Walker Lane: Overview, Rationale, and Objectives

NASA Astrophysics Data System (ADS)

Stockli, D. F.

2006-12-01

GeoFrame is an integrative geologic initiative that takes a multi-dimensional view of the building and modification of the North American continent by systematic integration of geologic and geochronometric investigations and the results from unprecedented geophysical imaging as part of the Earthscope Program. The GeoFrame effort envisions these focus site investigations to entail map-scale arrays of passive source seismic receivers and associated active source seismic studies and complementary geophysics in conjunction with geologic-based synthesis and targeted studies. One of these focus sites is the Walker Lane region in eastern California and western Nevada, situated between the Basin and Range province and the unextended Sierra Nevada block. This GeoFrame focus site workshop is particularly timely given the deployment schedule of the USArray "BigFoot" array. The Walker Lane intraplate deformation zone accommodates nearly ~25% of present-day relative motion between the Pacific and North American plates and might represent an incipient plate boundary. It provides a world-class example of the present modification of continental lithosphere by the process of transcurrent faulting and rifting and offers the opportunity to seamlessly integrate surface geology, structural geology, petrology, geo- and thermochronology, and the history of the continental lithosphere with ongoing processes in the Earth's mantle. It affords opportunities to address a number of questions posed within Earthscope such as: mechanisms of strain transfer, the role of lithospheric rheology in strain localization and seismic response, the nature and timescales of transient fault behavior, and the role of magmas and fluids in deforming lithosphere. Implicit in the design and implementation of Earthscope is the recognition that progress on issues such as these requires an integrative geophysical and geological investigation of the Walker Lane. As such, it will open new avenues of collaboration and identify new research needs and opportunities. We anticipate the integration of results and efforts with ongoing Earthscope projects, such as Sierra Nevada efforts of SNEP as well as the NSF Margins Rupturing of Continental Lithosphere (RCL) initiative in the Gulf of California by continuing the work onshore from the Gulf of California to the north into Nevada.

Floaters and Sinkers: Solutions for Math and Science. Densities and Volumes. Book 5.

ERIC Educational Resources Information Center

Wiebe, Arthur, Ed.; And Others

Developed to serve as a way to integrate mathematics skills and science processes, this booklet provides activities which demonstrate the concept of density for students of grades five through nine. Investigations are offered on the densities of water, salt, salt water, and woods. Opportunities are also provided in computing volumes of cylinders…

Using Simple Machines to Leverage Learning

ERIC Educational Resources Information Center

Dotger, Sharon

2008-01-01

What would your students say if you told them they could lift you off the ground using a block and a board? Using a simple machine, they'll find out they can, and they'll learn about work, energy, and motion in the process! In addition, this integrated lesson gives students the opportunity to investigate variables while practicing measurement…

An Analysis of Teacher-Student Interaction Patterns in a Robotics Course for Kindergarten Children: A Pilot Study

ERIC Educational Resources Information Center

Liu, Eric Zhi-Feng; Lin, Chun-Hung; Liou, Pey-Yan; Feng, Han-Chuan; Hou, Huei-Tse

2013-01-01

Compared with other media, programmable bricks provide children with the opportunity to create their own product and, through this process, to express creative thinking. Studies have found that learning robotics or integrating programming bricks into courses can help to develop students' problem-solving abilities and enhance their learning…

Investigating the Effects of Authentic Activities on Foreign Language Learning: A Design-Based Research Approach

ERIC Educational Resources Information Center

Ozverir, Ildeniz; Osam, Ulker Vanci; Herrington, Jan

2017-01-01

Achieving communicative competency in English classes has been a key goal in contexts where English is taught as a foreign language (EFL). During this process, however, integrating the difficulty and complexity of real life tasks into classroom teaching has often been disregarded. Lack of opportunities for authentic language use often results in…

Mobile Apps to Support and Assess Foreign Language Learning

ERIC Educational Resources Information Center

Berns, Anke; Palomo-Duarte, Manuel; Dodero, Juan Manuel; Ruiz-Ladrón, Juan Miguel; Márquez, Andrea Calderón

2015-01-01

In the last two decades there have been many attempts to integrate all kinds of mobile devices and apps to support formal as well as informal learning processes. However, most of the available apps still support mainly individual learning, using mobile devices to deliver content rather than providing learners with the opportunity to interact with…

Bringing RNA into View: RNA and Its Roles in Biology.

ERIC Educational Resources Information Center

Atkins, John F.; Ellington, Andrew; Friedman, B. Ellen; Gesteland, Raymond F.; Noller, Harry F.; Pasquale, Stephen M.; Storey, Richard D.; Uhlenbeck, Olke C.; Weiner, Alan M.

This guide presents a module for college students on ribonucleic acid (RNA) and its role in biology. The module aims to integrate the latest research and its findings into college-level biology and provide an opportunity for students to understand biological processes. Four activities are presented: (1) "RNA Structure: Tapes to Shapes"; (2) "RNA…

Integrating Electronic Reverse Auctions into Defense Procurement: Exploratory Research on Opportunities, Issues, Processes, Risks, and Cultural Implications

DTIC Science & Technology

2009-12-18

TAM ) ...............................................21 F. Relational Exchange...SAF/AQC Secretary of the Air Force for Acquisition TAM Technology Adoption Model UA Uncertainty Avoidance USAAVE United States Army...of policy, thereby (1) easing the learning curve for individual COs, (2) maximizing e-RA use where it is appropriate and (3) saving substantial

Integrated control-structure design

NASA Technical Reports Server (NTRS)

Hunziker, K. Scott; Kraft, Raymond H.; Bossi, Joseph A.

1991-01-01

A new approach for the design and control of flexible space structures is described. The approach integrates the structure and controller design processes thereby providing extra opportunities for avoiding some of the disastrous effects of control-structures interaction and for discovering new, unexpected avenues of future structural design. A control formulation based on Boyd's implementation of Youla parameterization is employed. Control design parameters are coupled with structural design variables to produce a set of integrated-design variables which are selected through optimization-based methodology. A performance index reflecting spacecraft mission goals and constraints is formulated and optimized with respect to the integrated design variables. Initial studies have been concerned with achieving mission requirements with a lighter, more flexible space structure. Details of the formulation of the integrated-design approach are presented and results are given from a study involving the integrated redesign of a flexible geostationary platform.

'Act on oncology' as a new comprehensive approach to assess prostate cancer centres--method description and results of a pilot study.

PubMed

Voigt, Wieland; Hoellthaler, Josef; Magnani, Tiziana; Corrao, Vito; Valdagni, Riccardo

2014-01-01

Multidisciplinary care of prostate cancer is increasingly offered in specialised cancer centres. It requires the optimisation of medical and operational processes and the integration of the different medical and non-medical stakeholders. To develop a standardised operational process assessment tool basing on the capability maturity model integration (CMMI) able to implement multidisciplinary care and improve process quality and efficiency. Information for model development was derived from medical experts, clinical guidelines, best practice elements of renowned cancer centres, and scientific literature. Data were organised in a hierarchically structured model, consisting of 5 categories, 30 key process areas, 172 requirements, and more than 1500 criteria. Compliance with requirements was assessed through structured on-site surveys covering all relevant clinical and management processes. Comparison with best practice standards allowed to recommend improvements. 'Act On Oncology'(AoO) was applied in a pilot study on a prostate cancer unit in Europe. Several best practice elements such as multidisciplinary clinics or advanced organisational measures for patient scheduling were observed. Substantial opportunities were found in other areas such as centre management and infrastructure. As first improvements the evaluated centre administration described and formalised the organisation of the prostate cancer unit with defined personnel assignments and clinical activities and a formal agreement is being worked on to have structured access to First-Aid Posts. In the pilot study, the AoO approach was feasible to identify opportunities for process improvements. Measures were derived that might increase the operational process quality and efficiency.

Atmospheric rivers and past hydrometeorological extremes: Challenges and opportunities

NASA Astrophysics Data System (ADS)

Sodemann, Harald

2017-04-01

Atmospheric rivers are a key term for describing water vapour transport in extratropical regions. The concept has become particularly valuable for linking meteorological process understanding with research focused on the impacts of heavy precipitation. Atmospheric rivers are narrow, elongated features of high integrated water vapour and water vapour flux can lead to severe precipitation and flooding if moisture is extracted efficiently. The orographic rises at the West Coast of the United States and Western Norway are regions where Atmospheric Rivers are one of the prime mechanisms for moisture delivery and precipitation extremes in the present climate. Due to the small horizontal scales of some of the processes climate models are challenged to represent this important transport process between mid-latitudes and the subtropics faithfully. Recent aircraft data and regional tracer model studies provide new insight into the formation and moisture transport mechanisms. In this study I review the concept and pertinent processes of Atmospheric Rivers, thereby focusing on caveats, challenges and opportunities for understanding past hydrometeorological extremes.

Transforming nanomedicine manufacturing toward Quality by Design and microfluidics.

PubMed

Colombo, Stefano; Beck-Broichsitter, Moritz; Bøtker, Johan Peter; Malmsten, Martin; Rantanen, Jukka; Bohr, Adam

2018-04-05

Nanopharmaceuticals aim at translating the unique features of nano-scale materials into therapeutic products and consequently their development relies critically on the progression in manufacturing technology to allow scalable processes complying with process economy and quality assurance. The relatively high failure rate in translational nanopharmaceutical research and development, with respect to new products on the market, is at least partly due to immature bottom-up manufacturing development and resulting sub-optimal control of quality attributes in nanopharmaceuticals. Recently, quality-oriented manufacturing of pharmaceuticals has undergone an unprecedented change toward process and product development interaction. In this context, Quality by Design (QbD) aims to integrate product and process development resulting in an increased number of product applications to regulatory agencies and stronger proprietary defense strategies of process-based products. Although QbD can be applied to essentially any production approach, microfluidic production offers particular opportunities for QbD-based manufacturing of nanopharmaceuticals. Microfluidics provides unique design flexibility, process control and parameter predictability, and also offers ample opportunities for modular production setups, allowing process feedback for continuously operating production and process control. The present review aims at outlining emerging opportunities in the synergistic implementation of QbD strategies and microfluidic production in contemporary development and manufacturing of nanopharmaceuticals. In doing so, aspects of design and development, but also technology management, are reviewed, as is the strategic role of these tools for aligning nanopharmaceutical innovation, development, and advanced industrialization in the broader pharmaceutical field. Copyright © 2018 Elsevier B.V. All rights reserved.

Integrating the fundamentals of care framework in baccalaureate nursing education: An example from a nursing school in Denmark.

PubMed

Voldbjerg, Siri Lygum; Laugesen, Britt; Bahnsen, Iben Bøgh; Jørgensen, Lone; Sørensen, Ingrid Maria; Grønkjaer, Mette; Sørensen, Erik Elgaard

2018-06-01

To describe and discuss the process of integrating the Fundamentals of Care framework in a baccalaureate nursing education at a School of Nursing in Denmark. Nursing education plays an essential role in educating nurses to work within healthcare systems in which a demanding workload on nurses results in fundamental nursing care being left undone. Newly graduated nurses often lack knowledge and skills to meet the challenges of delivering fundamental care in clinical practice. To develop nursing students' understanding of fundamental nursing, the conceptual Fundamentals of Care framework has been integrated in nursing education at a School of Nursing in Denmark. Discursive paper using an adjusted descriptive case study design for describing and discussing the process of integrating the conceptual Fundamentals of Care Framework in nursing education. The process of integrating the Fundamentals of Care framework is illuminated through a description of the context, in which the process occurs including the faculty members, lectures, case-based work and simulation laboratory in nursing education. Based on this description, opportunities such as supporting a holistic approach to an evidence-based integrative patient care and challenges such as scepticism among the faculty are discussed. It is suggested how integration of Fundamentals of Care Framework in lectures, case-based work and simulation laboratory can make fundamental nursing care more explicit in nursing education, support critical thinking and underline the relevance of evidence-based practice. The process relies on a supportive context, a well-informed and engaged faculty, and continuous reflections on how the conceptual framework can be integrated. Integrating the Fundamentals of Care framework can support nursing students' critical thinking and reflection on what fundamental nursing care is and requires and eventually educate nurses in providing evidence-based fundamental nursing care. © 2018 John Wiley & Sons Ltd.

A Value Analysis of Lean Processes in Target Value Design and Integrated Project Delivery.

PubMed

Nanda, Upali; K Rybkowski, Zofia; Pati, Sipra; Nejati, Adeleh

2017-04-01

To investigate what key stakeholders consider to be the advantages and the opportunities for improvement in using lean thinking and tools in the integrated project delivery (IPD) process. A detailed literature review was followed by case study of a Lean-IPD project. Interviews with members of the project leadership team, focus groups with the integrated team as well as the design team, and an online survey of all stakeholders were conducted. Statistical analysis and thematic content analysis were used to analyze the data, followed by a plus-delta analysis. (1) Learning is a large, implicit benefit of Lean-IPD that is not currently captured by any success metric; (2) the cardboard mock-up was the most successful lean strategy; (3) although a collaborative project, the level of influence of different stakeholder groups was perceived to be different by different stakeholders; (4) overall, Lean-IPD was rated as better than traditional design-bid-build methods; and (5) opportunities for improvement reported were increase in accurate cost estimating, more efficient use of time, perception of imbalance of control/influence, and need for facilitation (which represents different points of view). While lean tools and an IPD method are preferred to traditional design-bid-build methods, the perception of different stakeholders varies and more work needs to be done to allow a truly shared decision-making model. Learning was identified as one of the biggest advantages.

From the past to the future: Integrating work experience into the design process.

PubMed

Bittencourt, João Marcos; Duarte, Francisco; Béguin, Pascal

2017-01-01

Integrating work activity issues into design process is a broadly discussed theme in ergonomics. Participation is presented as the main means for such integration. However, a late participation can limit the development of both project solutions and future work activity. This article presents the concept of construction of experience aiming at the articulated development of future activities and project solutions. It is a non-teleological approach where the initial concepts will be transformed by the experience built up throughout the design process. The method applied was a case study of an ergonomic participation during the design of a new laboratory complex for biotechnology research. Data was obtained through analysis of records in a simulation process using a Lego scale model and interviews with project participants. The simulation process allowed for developing new ways of working and generating changes in the initial design solutions, which enable workers to adopt their own developed strategies for conducting work more safely and efficiently in the future work system. Each project decision either opens or closes a window of opportunities for developing a future activity. Construction of experience in a non-teleological design process allows for understanding the consequences of project solutions for future work.

Quality by design case study: an integrated multivariate approach to drug product and process development.

PubMed

Huang, Jun; Kaul, Goldi; Cai, Chunsheng; Chatlapalli, Ramarao; Hernandez-Abad, Pedro; Ghosh, Krishnendu; Nagi, Arwinder

2009-12-01

To facilitate an in-depth process understanding, and offer opportunities for developing control strategies to ensure product quality, a combination of experimental design, optimization and multivariate techniques was integrated into the process development of a drug product. A process DOE was used to evaluate effects of the design factors on manufacturability and final product CQAs, and establish design space to ensure desired CQAs. Two types of analyses were performed to extract maximal information, DOE effect & response surface analysis and multivariate analysis (PCA and PLS). The DOE effect analysis was used to evaluate the interactions and effects of three design factors (water amount, wet massing time and lubrication time), on response variables (blend flow, compressibility and tablet dissolution). The design space was established by the combined use of DOE, optimization and multivariate analysis to ensure desired CQAs. Multivariate analysis of all variables from the DOE batches was conducted to study relationships between the variables and to evaluate the impact of material attributes/process parameters on manufacturability and final product CQAs. The integrated multivariate approach exemplifies application of QbD principles and tools to drug product and process development.

From traditional to patient-centered learning: curriculum change as an intervention for changing institutional culture and promoting professionalism in undergraduate medical education.

PubMed

Christianson, Charles E; McBride, Rosanne B; Vari, Richard C; Olson, Linda; Wilson, H David

2007-11-01

The authors reframe a curriculum change from a traditional lecture-based to an integrated patient-centered approach as an intervention for changing the culture and hidden curriculum of an institution in ways that promote professionalism. Within this context, the authors articulate some of the inherent process and relational factors brought about by these curricular changes that are essential elements of this intervention process. In 1998 the University of North Dakota School of Medicine and Health Sciences (UNDSMHS) introduced a new preclinical patient-centered learning (PCL) curriculum for first- and second-year medical students. Case-based, small-group learning forms the critical foundation of the PCL process, and an integrated basic and clinical science didactic component supports this process. At the student level, the case-based PCL process generates innovative opportunities for professionalism education from the explicitly articulated formal content that arises naturally from the cases, but more importantly from the implicit values inherent to the PCL small-group process itself--humanism, accountability, pursuit of excellence, and altruism. Further, the organizational changes necessary for the transformation to the PCL curriculum required process changes at student, faculty, and administrative levels that have resulted in a cultural shift toward relationship centeredness within the institution. The authors describe the evolution and structure of the PCL curriculum at UNDSMHS and how this curricular transformation has served as an intervention that promotes professionalism and institutional culture change through (1) processes at the student level that present new opportunities for professionalism education, and (2) processes at student, faculty, administrative, and institutional levels that have created an institutional culture that supports, models, and promotes relationship-centered professional values.

Evolution of Mobil`s methods to evaluate exploration and producing opportunities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gaynor, C.B.; Cook, D.M. Jr.

1996-08-01

Over the past decade, Mobil has changed significantly in size, structure and focus to improve profitability. Concurrently, work processes and methodologies have been modified to improve resource utilization and opportunity selection. The key imperative has been recognition of the full range of hydrocarbon volume uncertainty, its risk and value. Exploration has focussed on increasing success through improved geotechnical estimates and demonstrating value addition. For Producing, the important tasks: (1) A centralized Exploration and Producing team was formed to help ensure an integrated, consistent worldwide approach to prospect and field assessments. Monte Carlo simulation was instituted to recognize probability-weighted ranges ofmore » possible outcomes for prospects and fields, and hydrocarbon volume category definitions were standardized. (2) Exploration instituted a global Prospect Inventory, tracking wildcat predictions vs. results. Performance analyses led to initiatives to improve the quality and consistency of assessments. Process improvement efforts included the use of multidisciplinary teams and peer reviews. Continued overestimates of hydrocarbon volumes prompted methodology changes such as the use of {open_quotes}reality checks{close_quotes} and log-normal distributions. The communication of value predictions and additions became paramount. (3) Producing now recognizes the need for Exploration`s commercial discoveries and new Producing ventures, notwithstanding the associated risk. Multi-disciplinary teams of engineers and geoscientists work on post-discovery assessments to optimize field development and maximize the value of opportunities. Mobil now integrates volume and risk assessment with correlative future capital investment programs to make proactive strategic choices to maximize shareholder value.« less

Classroom ICT Integration in Tanzania: Opportunities and Challenges from the Perspectives of TPACK and SAMR Models

ERIC Educational Resources Information Center

Kihoza, Patrick; Zlotnikova, Irina; Bada, Joseph; Kalegele, Khamisi

2016-01-01

With the education systems demand of contemporary technologies, teacher trainees should be imparted with competencies and skills to integrate information and communication technology (ICT) into their future teaching and learning practices. This study assessed classroom ICTs integration opportunities and the challenges in relation to Technological…

Designing authentic assessment: strategies for nurse educators.

PubMed

Poindexter, Kathleen; Hagler, Debra; Lindell, Deborah

2015-01-01

Increased emphasis on health care safety requires renewed attention to teaching and learning processes for future health care professionals. When presented with problems situated in a clinical context, learners have rich opportunities to demonstrate integration of concepts. Authentic assessment is an approach to evaluation of learning through which students can demonstrate acquired knowledge, skills, and attitudes in the context of real-world or realistic nursing practice activities. This article describes features, approaches, and examples of authentic assessment processes in the context of classroom, clinical, and online nursing education.

Data warehousing leads to improved business performance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Morris, R.

1995-09-01

Data warehousing is emerging as one of the most significant trends in information technology (IT) during the 1990s. According to William H. Inmon, sometimes referred to as the father of data warehousing, a data warehouse is a subject-oriented, integrated, nonvolatile, time-variant collection of data organized to support management needs. Data warehousing can: provide integrated, historical and operational data; integrate disparate application systems; and organize and store data for informational, analytical processing. Data warehousing offers opportunity to address today`s problems of realizing a return on massive investments being made in acquiring and managing E and P data. Effective implementations require anmore » understanding of business benefits being sought and an adaptive, flexible IT architecture for supporting processes and technologies involved. As national E and P data archives continue to emerge and complement existing data reserves within E and P companies, expect to see increased data warehousing use to merge these two environments.« less

Selection and Manufacturing of Membrane Materials for Solar Sails

NASA Technical Reports Server (NTRS)

Bryant, Robert G.; Seaman, Shane T.; Wilkie, W. Keats; Miyaucchi, Masahiko; Working, Dennis C.

2013-01-01

Commercial metallized polyimide or polyester films and hand-assembly techniques are acceptable for small solar sail technology demonstrations, although scaling this approach to large sail areas is impractical. Opportunities now exist to use new polymeric materials specifically designed for solar sailing applications, and take advantage of integrated sail manufacturing to enable large-scale solar sail construction. This approach has, in part, been demonstrated on the JAXA IKAROS solar sail demonstrator, and NASA Langley Research Center is now developing capabilities to produce ultrathin membranes for solar sails by integrating resin synthesis with film forming and sail manufacturing processes. This paper will discuss the selection and development of polymer material systems for space, and these new processes for producing ultrathin high-performance solar sail membrane films.

The Sensor Management for Applied Research Technologies (SMART) Project

NASA Technical Reports Server (NTRS)

Goodman, Michael; Jedlovec, Gary; Conover, Helen; Botts, Mike; Robin, Alex; Blakeslee, Richard; Hood, Robbie; Ingenthron, Susan; Li, Xiang; Maskey, Manil;

Charting a path to efficiencies following a merger.

PubMed

Klar, Brandon; Shufelt, Gregory P

2015-06-01

Health systems can access the full range of opportunities for enhanced efficiencies following a merger or an acquisition by pursuing the following five-step process, which constitutes the development of a business plan of operational efficiencies: Secure executive sponsorship and involvement. Establish an integration steering committee. Develop guiding principles. Identify and validate potential efficiencies. Develop an action plan for each department and function.

Sports Competition--Integrated or Segregated? Which Is Better for Your Child?

ERIC Educational Resources Information Center

Grosse, Susan J.

2008-01-01

Selecting competitive sports opportunities for a child is a challenging process. Parents have to make the right choices so that their young athletes will have many years of healthy, happy, active experiences. If parents make the wrong choices, their son or daughter will have, at the very least, a few unhappy hours, and worst-case scenario, could…

Death and Dying--A Living Study. Profiles of Promise 35.

ERIC Educational Resources Information Center

Hawke, Sharryl

Realizing that all students have to deal with death at some time, yet receive no formal education in the subject, Alex Kramer, a high school teacher at Moon High School, Corapolis, Pennsylvania, decided to create a program which would give students an opportunity to study death and the process of dying as integral parts of life. Kramer's goals,…

Gender Equality and Equity: A Summary Review of UNESCO's Accomplishments since the Fourth World Conference on Women (Beijing 1995).

ERIC Educational Resources Information Center

Pavlic, Breda; Ruprecht, Lydia; Sam-Vargas, Susana

The current process of reform of the United Nations Educational, Scientific and Cultural Organization (UNESCO) and the preparation of a new 6-year strategy for 2001-2006 provide an opportunity to integrate fully into its planning, programming, implementation, and evaluation a gender mainstreaming practice advocated by the United Nations and other…

Integrating Research on How People Learn and Learning across Settings as a Window of Opportunity to Address Inequality in Educational Processes and Outcomes

ERIC Educational Resources Information Center

Lee, Carol D.

2017-01-01

This chapter addresses how fundamental principles regarding how people learn in the last decade open up possibilities for conceptualizing a broad ecological culturally rooted framework for the design of robust learning environments in a variety of settings, especially schools. These cross-disciplinary principles emerging from across relevant…

"Reflecting on Reflections:" Curating ePortfolios for Integrative Learning and Identity Development in a General Education Senior Capstone

ERIC Educational Resources Information Center

Schrand, Tom; Jones, Katharine; Hanson, Valerie

2018-01-01

By embedding an ePortfolio process in a general education core that culminates with a senior capstone course, Thomas Jefferson University has created an opportunity for students to use their completed ePortfolios as archives of primary sources that they can curate to produce narratives about their intellectual development. The result was a…

Nuclear-renewable hybrid energy systems: Opportunities, interconnections, and needs

DOE PAGES

Ruth, Mark F.; Zinaman, Owen R.; Antkowiak, Mark; ...

2013-12-20

As the U.S. energy system evolves, the amount of electricity from variable-generation sources is likely to increase, which could result in additional times when electricity demand is lower than available production. Therefore, purveyors of technologies that traditionally have provided base-load electricity—such as nuclear power plants—can explore new operating procedures to deal with the associated market signals. Concurrently, innovations in nuclear reactor design coupled with sophisticated control systems now allow for more complex apportionment of heat within an integrated system such as one linked to energy-intensive chemical processes. Our paper explores one opportunity – nuclear-renewable hybrid energy systems. These are definedmore » as integrated facilities comprised of nuclear reactors, renewable energy generation, and industrial processes that can simultaneously address the need for grid flexibility, greenhouse gas emission reductions, and optimal use of investment capital. Six aspects of interaction (interconnections) between elements of nuclear-renewable hybrid energy systems are identified: Thermal, electrical, chemical, hydrogen, mechanical, and information. In addition, system-level aspects affect selection, design, and operation of this hybrid system type. Throughout the paper, gaps and research needs are identified to promote further exploration of the topic.« less

What propels sexual murderers: a proposed integrated theory of social learning and routine activities theories.

PubMed

Chan, Heng Choon Oliver; Heide, Kathleen M; Beauregard, Eric

2011-04-01

Despite the great interest in the study of sexual homicide, little is known about the processes involved in an individual's becoming motivated to sexually kill, deciding to sexually kill, and acting on that desire, intention, and opportunity. To date, no comprehensive model of sexual murdering from the offending perspective has been proposed in the criminological literature. This article incorporates the works of Akers and Cohen and Felson regarding their social learning theory and routine activities theory, respectively, to construct an integrated conceptual offending framework in sexual homicide. This integrated model produces a stronger and more comprehensive explanation of sexual murder than any single theory currently available.

XML-based approaches for the integration of heterogeneous bio-molecular data.

PubMed

Mesiti, Marco; Jiménez-Ruiz, Ernesto; Sanz, Ismael; Berlanga-Llavori, Rafael; Perlasca, Paolo; Valentini, Giorgio; Manset, David

2009-10-15

The today's public database infrastructure spans a very large collection of heterogeneous biological data, opening new opportunities for molecular biology, bio-medical and bioinformatics research, but raising also new problems for their integration and computational processing. In this paper we survey the most interesting and novel approaches for the representation, integration and management of different kinds of biological data by exploiting XML and the related recommendations and approaches. Moreover, we present new and interesting cutting edge approaches for the appropriate management of heterogeneous biological data represented through XML. XML has succeeded in the integration of heterogeneous biomolecular information, and has established itself as the syntactic glue for biological data sources. Nevertheless, a large variety of XML-based data formats have been proposed, thus resulting in a difficult effective integration of bioinformatics data schemes. The adoption of a few semantic-rich standard formats is urgent to achieve a seamless integration of the current biological resources.

Opportunities for Breakthroughs in Large-Scale Computational Simulation and Design

NASA Technical Reports Server (NTRS)

Alexandrov, Natalia; Alter, Stephen J.; Atkins, Harold L.; Bey, Kim S.; Bibb, Karen L.; Biedron, Robert T.; Carpenter, Mark H.; Cheatwood, F. McNeil; Drummond, Philip J.; Gnoffo, Peter A.

2002-01-01

Opportunities for breakthroughs in the large-scale computational simulation and design of aerospace vehicles are presented. Computational fluid dynamics tools to be used within multidisciplinary analysis and design methods are emphasized. The opportunities stem from speedups and robustness improvements in the underlying unit operations associated with simulation (geometry modeling, grid generation, physical modeling, analysis, etc.). Further, an improved programming environment can synergistically integrate these unit operations to leverage the gains. The speedups result from reducing the problem setup time through geometry modeling and grid generation operations, and reducing the solution time through the operation counts associated with solving the discretized equations to a sufficient accuracy. The opportunities are addressed only at a general level here, but an extensive list of references containing further details is included. The opportunities discussed are being addressed through the Fast Adaptive Aerospace Tools (FAAST) element of the Advanced Systems Concept to Test (ASCoT) and the third Generation Reusable Launch Vehicles (RLV) projects at NASA Langley Research Center. The overall goal is to enable greater inroads into the design process with large-scale simulations.

Integration of Field Geophysics and Geology in an International Setting: Multidisciplinary Geoscience Field Experience at the University of Western Ontario

NASA Astrophysics Data System (ADS)

Brenders, A. J.; Banerjee, N.; Pratt, R. G.

2010-12-01

The pedagogical value of the field experience is unequaled: students, teaching assistants, and professors alike return with a renewed sense of purpose, community, and the context in which to place classroom education. It is widely regarded as valuable to personal development, and is required by the Canadian Council of Professional Geoscientists for professional registration. As part of our ongoing International Geoscience Field Experience Initiative, Earth Sciences students at the University of Western Ontario have the opportunity to enhance their education through a study abroad program. The focus is on a residential field experience to world-class localities, offered with the collaboration of internationally recognized academic researchers, government survey personnel, and industry leaders. Recent trips have included the Sn-W mineralization in the Cornwall district of the U.K., the Iberian Pyrite Belt (IPB) in Portugal and Spain, and the metallogenic belts of Western Turkey. The integration of geological knowledge with geophysical data was one of the key organizing principles of our recent field trips to the IPB and Western Turkey. This integration is a foundation of modern Earth Sciences, and common practice in industry, it is relatively rare in classroom settings. Lectures before departure and evening exercises during the field trip supplemented the core undergraduate curriculum in geophysics, reviewing gravity, DC resistivity, induced polarization (IP), and magnetotelluric methods, focusing on application to mineral exploration. During our trip to the IPB, partnership with industry allowed students the opportunity to work with state of the art geophysical data, acquired on an exploration prospect visited during the field trip. Multi-parameter geophysical inversions of the IP and MT data produced cross-sections in depth - results interpretable by the students in the complex geological environment of the Iberian Pyrite Belt. Although the students gained valuable geological insight, the lack of practical experience in the acquisition and processing of geophysical data was identified in course evaluations. To address this, in Western Turkey, students had the opportunity to design and acquire total magnetic field surveys using a walking magnetometer, combining a GPS receiver and proton-precession magnetometer. Using this instrument, students identified the geophysical response of subsurface features, visible in both outcrop and during traverse through open pit mines. A transect across a buried basalt - limestone contact was made, and the strike of the contact identified during subsequent data processing. Students also had the opportunity to visit an active IP-resistivity survey, observing the acquisition of this data in the field, and learn how project geologists integrate this data with geological drill cores. Finally, students designed and acquired a total magnetic field survey over an archaeological site: the Acropolis at Pergamon. By integrating data acquisition, processing, and interpretation with field visits to sites of both geological and archaeological interest, students acquired field and technical skills that ideally prepared them for a future in research or industry.

Extended device profiles and testing procedures for the approval process of integrated medical devices using the IEEE 11073 communication standard.

PubMed

Janß, Armin; Thorn, Johannes; Schmitz, Malte; Mildner, Alexander; Dell'Anna-Pudlik, Jasmin; Leucker, Martin; Radermacher, Klaus

2018-02-23

Nowadays, only closed and proprietary integrated operating room systems (IORS) from big manufacturers are available on the market. Hence, the interconnection of components from third-party vendors is only possible with increased time and costs. In the context of the German Federal Ministry of Education and Research (BMBF)-funded project OR.NET (2012-2016), the open integration of medical devices from different manufacturers was addressed. An integrated operating theater based on the open communication standard IEEE 11073 shall give clinical operators the opportunity to choose medical devices independently of the manufacturer. This approach would be advantageous especially for hospital operators and small- and medium-sized enterprises (SME) of medical devices. Actual standards and concepts regarding technical feasibility and the approval process do not cope with the requirements for a modular integration of medical devices in the operating room (OR), based on an open communication standard. Therefore, innovative approval strategies and corresponding certification and test procedures, which cover actual legal and normative standards, have to be developed in order to support the future risk management and the usability engineering process of open integrated medical devices in the OR. The use of standardized device and service profiles and a three-step testing procedure, including conformity, interoperability and integration tests are described in this paper and shall support the manufacturers to integrate their medical devices without disclosing the medical devices' risk analysis and related confidential expertise or proprietary information.

Citizen science in hydrology and water resources: opportunities for knowledge generation, ecosystem service management, and sustainable development

NASA Astrophysics Data System (ADS)

Buytaert, Wouter; Zulkafli, Zed; Grainger, Sam; Acosta, Luis; Bastiaensen, Johan; De Bièvre, Bert; Bhusal, Jagat; Chanie, Tilashwork; Clark, Julian; Dewulf, Art; Foggin, Marc; Hannah, David; Hergarten, Christian; Isaeva, Aiganysh; Karpouzoglou, Timos; Pandey, Bhopal; Paudel, Deepak; Sharma, Keshav; Steenhuis, Tammo; Tilahun, Seifu; Van Hecken, Gert; Zhumanova, Munavar

2014-10-01

The participation of the general public in the research design, data collection and interpretation process together with scientists is often referred to as citizen science. While citizen science itself has existed since the start of scientific practice, developments in sensing technology, data processing and visualisation, and communication of ideas and results, are creating a wide range of new opportunities for public participation in scientific research. This paper reviews the state of citizen science in a hydrological context and explores the potential of citizen science to complement more traditional ways of scientific data collection and knowledge generation for hydrological sciences and water resources management. Although hydrological data collection often involves advanced technology, the advent of robust, cheap and low-maintenance sensing equipment provides unprecedented opportunities for data collection in a citizen science context. These data have a significant potential to create new hydrological knowledge, especially in relation to the characterisation of process heterogeneity, remote regions, and human impacts on the water cycle. However, the nature and quality of data collected in citizen science experiments is potentially very different from those of traditional monitoring networks. This poses challenges in terms of their processing, interpretation, and use, especially with regard to assimilation of traditional knowledge, the quantification of uncertainties, and their role in decision support. It also requires care in designing citizen science projects such that the generated data complement optimally other available knowledge. Lastly, we reflect on the challenges and opportunities in the integration of hydrologically-oriented citizen science in water resources management, the role of scientific knowledge in the decision-making process, and the potential contestation to established community institutions posed by co-generation of new knowledge.

‘Act on Oncology’ as a New Comprehensive Approach to Assess Prostate Cancer Centres – Method Description and Results of a Pilot Study

PubMed Central

Voigt, Wieland; Hoellthaler, Josef; Magnani, Tiziana; Corrao, Vito; Valdagni, Riccardo

2014-01-01

Background Multidisciplinary care of prostate cancer is increasingly offered in specialised cancer centres. It requires the optimisation of medical and operational processes and the integration of the different medical and non-medical stakeholders. Objective To develop a standardised operational process assessment tool basing on the capability maturity model integration (CMMI) able to implement multidisciplinary care and improve process quality and efficiency. Design, Setting, and Participants Information for model development was derived from medical experts, clinical guidelines, best practice elements of renowned cancer centres, and scientific literature. Data were organised in a hierarchically structured model, consisting of 5 categories, 30 key process areas, 172 requirements, and more than 1500 criteria. Compliance with requirements was assessed through structured on-site surveys covering all relevant clinical and management processes. Comparison with best practice standards allowed to recommend improvements. ‘Act On Oncology’(AoO) was applied in a pilot study on a prostate cancer unit in Europe. Results and Limitations Several best practice elements such as multidisciplinary clinics or advanced organisational measures for patient scheduling were observed. Substantial opportunities were found in other areas such as centre management and infrastructure. As first improvements the evaluated centre administration described and formalised the organisation of the prostate cancer unit with defined personnel assignments and clinical activities and a formal agreement is being worked on to have structured access to First-Aid Posts. Conclusions In the pilot study, the AoO approach was feasible to identify opportunities for process improvements. Measures were derived that might increase the operational process quality and efficiency. PMID:25192213

Polarimetric radar and aircraft observations of saggy bright bands during MC3E

DOE PAGES

Matthew R. Kumjian; Giangrande, Scott E.; Mishra, Subashree; ...

2016-03-19

Polarimetric radar observations increasingly are used to understand cloud microphysical processes, which is critical for improving their representation in cloud and climate models. In particular, there has been recent focus on improving representations of ice collection processes (e.g., aggregation, riming), as these influence precipitation rate, heating profiles, and ultimately cloud life cycles. However, distinguishing these processes using conventional polarimetric radar observations is difficult, as they produce similar fingerprints. This necessitates improved analysis techniques and integration of complementary data sources. Furthermore, the Midlatitude Continental Convective Clouds Experiment (MC3E) provided such an opportunity.

Reverse osmosis integrity monitoring in water reuse: The challenge to verify virus removal - A review.

PubMed

Pype, Marie-Laure; Lawrence, Michael G; Keller, Jurg; Gernjak, Wolfgang

2016-07-01

A reverse osmosis (RO) process is often included in the treatment train to produce high quality reuse water from treated effluent for potable purposes because of its high removal efficiency for salinity and many inorganic and organic contaminants, and importantly, it also provides an excellent barrier for pathogens. In order to ensure the continued protection of public health from pathogen contamination, monitoring RO process integrity is necessary. Due to their small sizes, viruses are the most difficult class of pathogens to be removed in physical separation processes and therefore often considered the most challenging pathogen to monitor. To-date, there is a gap between the current log credit assigned to this process (determined by integrity testing approved by regulators) and its actual log removal capability as proven in a variety of laboratory and pilot studies. Hence, there is a challenge to establish a methodology that more closely links to the theoretical performance. In this review, after introducing the notion of risk management in water reuse, we provide an overview of existing and potentially new RO integrity monitoring techniques, highlight their strengths and drawbacks, and debate their applicability to full-scale treatment plants, which open to future research opportunities. Copyright © 2016 Elsevier Ltd. All rights reserved.

GIS-based integrated assessment and decision support system for land use planning in consideration of carbon sequestration benefits

NASA Astrophysics Data System (ADS)

Wang, Jun; Chen, J. M.; Li, Manchun; Ju, Weimin

2007-06-01

As the major eligible land use activities in the Clean Development Mechanism (CDM), afforestation and reforestation offer opportunities and potential economic benefits for developing countries to participate in carbon-trade in the potential international carbon (C) sink markets. However, the design and selection of appropriate afforestation and reforestation locations in CDM are complex processes which need integrated assessment (IA) of C sequestration (CS) potential, environmental effects, and socio-economic impacts. This paper promotes the consideration of CS benefits in local land use planning and presents a GIS-based integrated assessment and spatial decision support system (IA-SDSS) to support decision-making on 'where' and 'how' to afforest. It integrates an Integrated Terrestrial Ecosystem Carbon Model (InTEC) and a GIS platform for modeling regional long-term CS potential and assessment of geo-referenced land use criteria including CS consequence, and produces ranking of plantation schemes with different tree species using the Analytic hierarchy process (AHP) method. Three land use scenarios are investigated: (i) traditional land use planning criteria without C benefits, (ii) land use for CS with low C price, and (iii) land use for CS with high price. Different scenarios and consequences will influence the weights of tree-species selection in the AHP decision process.

Integrated residential photovoltaic array development

NASA Astrophysics Data System (ADS)

Shepard, N. F., Jr.

1981-12-01

An advanced, universally-mountable, integrated residential photovoltaic array concept was defined based upon an in-depth formulation and evaluation of three candidate approaches which were synthesized from existing or proposed residential array concepts. The impact of module circuitry and process sequence is considered and technology gaps and performance drivers associated with residential photovoltaic array concepts are identified. The actual learning experience gained from the comparison of the problem areas of the hexagonal shingle design with the rectangular module design led to what is considered an advanced array concept. Building the laboratory mockup provided actual experience and the opportunity to uncover additional technology gaps.

[Why is brachytherapy still essential in 2017?

PubMed

Haie-Méder, C; Maroun, P; Fumagalli, I; Lazarescu, I; Dumas, I; Martinetti, F; Chargari, C

2018-05-16

These recent years, brachytherapy has benefited from imaging modalities advances. A more systematic use of tomodensitometric, ultrasonographic and MRI images during brachytherapy procedures has allowed an improvement in target and organs at risk assessment as well as their relationship with the applicators. New concepts integrating tumor regression during treatment have been defined and have been clinically validated. New applicators have been developed and are commercially available. Optimization processes have been developed, integrating hypofractionation modalities leading to tumor control improvement. All these opportunities led to further development of brachytherapy, with indisputable ballistic advantages, especially compared to external irradiation. Copyright © 2018. Published by Elsevier SAS.

Integrated residential photovoltaic array development

NASA Technical Reports Server (NTRS)

Shepard, N. F., Jr.

1981-01-01

An advanced, universally-mountable, integrated residential photovoltaic array concept was defined based upon an in-depth formulation and evaluation of three candidate approaches which were synthesized from existing or proposed residential array concepts. The impact of module circuitry and process sequence is considered and technology gaps and performance drivers associated with residential photovoltaic array concepts are identified. The actual learning experience gained from the comparison of the problem areas of the hexagonal shingle design with the rectangular module design led to what is considered an advanced array concept. Building the laboratory mockup provided actual experience and the opportunity to uncover additional technology gaps.

Integrating Work Experience with Classroom Instruction: A Strategy for Student Learning.

ERIC Educational Resources Information Center

Heinemann, Harry N.

1985-01-01

The measured results of one community college's experience with cooperative education suggest that incorporating productive work experience into classroom-based curricula can achieve excellence and equality of opportunity, offering opportunities for disadvantaged students without compromising academic integrity. (MSE)

Role of the single assessment process in the care of older people. How will primary dental care practitioners be involved?

PubMed

Lane, Elizabeth A; Gallagher, Jennifer E

2006-10-01

Following the publication of the National Service Framework for Older People, there have been developments across health and social care to facilitate holistic assessment of older people's needs, through what is called a 'single assessment process' or 'SAP'. In this paper, readers are introduced to the SAP. The process can be seen as a 'one-stop' approach to the assessment of vulnerable older people that facilitates cross-referral between the agencies involved and triggers access to dental care. The paper explores the benefits of this new way of working in support of older people and how it will provide an opportunity for innovative dental practitioners to integrate oral healthcare for people with complex health and social care needs into the SAP. In concludes that as local commissioning evolves, opportunities for practitioners to develop targeted services for this important patient group should be expanded to improve the uptake of healthcare and oral healthcare.

Water, energy, and biogeochemical budget research at Sleepers River Research Watershed, Vermont

USGS Publications Warehouse

Shanley, James B.; Sundquist, E.T.; Kendall, Carol

1995-01-01

The U.S. Geological Survey has selected the Sleepers River Research Watershed (Sleepers River) near Danville, Vt., as one of five sites for the investigation of Water, Energy, and Biogeochemical Budgets (WEBB). Sleepers River was chosen because it is a well-designed outdoor laboratory with a long history of hydrologic data collection and research, and also because it provides an ideal opportunity for collaboration among the U.S. Geological Survey, other Federal agencies, and universities at the site. The multiple subwatersheds at Sleepers River present a unique opportunity to investigate hydrologic, energy, and biogeochemical processes over a variety of spatial scales. This WEBB study builds on fundamental research on process mechanisms and rates at the plot scale (in this case, a hillslope). Results then are scaled up to interpret the hydrochemical response of first- and higher- order basins. Five research elements make up the Sleepers River WEBB project. Individually, each of the five elements is designed to investigate specific WEBB processes (such as CO2 efflux through a snowpack), address specific WEBB issues (such as scaling and flowpaths), or apply specific WEBB approaches (such as integrated chemical and physical study of a hillslope). The research elements overlap so that many of the processes investigated will be assessed in more than one way, thus allowing independent verification of research results. For example, flowpath information will be derived separately by use of isotopic tracers, conservative chemical solutes, and soil-moisture fluxes. Collectively, the five elements constitute an integrated approach to a comprehensive understanding of WEBB processes needed for the prediction of the effects of global change.

Improving Multimedia Foundations: Design of a Micro-Syllabus for Integrating Multimedia Modules into College Courses at the University of Delaware

ERIC Educational Resources Information Center

Davis, Aaron

2013-01-01

At the University of Delaware there has been growth in the use of multimedia technologies to facilitate the process of learning. However, many students entering higher educational institutions today, despite growing up with access to these tools, do not use them in interesting and meaningful ways. When given the opportunity to create multimedia…

Content and Language Integrated Learning in Higher Technical Education Using the "InGenio" Online Multimedia Authoring Tool

ERIC Educational Resources Information Center

Gimeno, Ana; Seiz, Rafael; de Siqueira, Jose Macario; Martinez, Antonio

2010-01-01

The future professional world of today's students is becoming a life-long learning process where they have to adapt to a changing market and an environment full of new opportunities and challenges. Thus, the development of a number of personal and professional skills, in addition to technical content and knowledge, is a crucial part of their…

Fully integrated carbon nanotube composite thin film strain sensors on flexible substrates for structural health monitoring

NASA Astrophysics Data System (ADS)

Burton, A. R.; Lynch, J. P.; Kurata, M.; Law, K. H.

2017-09-01

Multifunctional thin film materials have opened many opportunities for novel sensing strategies for structural health monitoring. While past work has established methods of optimizing multifunctional materials to exhibit sensing properties, comparatively less work has focused on their integration into fully functional sensing systems capable of being deployed in the field. This study focuses on the advancement of a scalable fabrication process for the integration of multifunctional thin films into a fully integrated sensing system. This is achieved through the development of an optimized fabrication process that can create a broad range of sensing systems using multifunctional materials. A layer-by-layer deposited multifunctional composite consisting of single walled carbon nanotubes (SWNT) in a polyvinyl alcohol and polysodium-4-styrene sulfonate matrix are incorporated with a lithography process to produce a fully integrated sensing system deposited on a flexible substrate. To illustrate the process, a strain sensing platform consisting of a patterned SWNT-composite thin film as a strain-sensitive element within an amplified Wheatstone bridge sensing circuit is presented. Strain sensing is selected because it presents many of the design and processing challenges that are core to patterning multifunctional thin film materials into sensing systems. Strain sensors fabricated on a flexible polyimide substrate are experimentally tested under cyclic loading using standard four-point bending coupons and a partial-scale steel frame assembly under lateral loading. The study reveals the material process is highly repeatable to produce fully integrated strain sensors with linearity and sensitivity exceeding 0.99 and 5 {{V}}/{ε }, respectively. The thin film strain sensors are robust and are capable of high strain measurements beyond 3000 μ {ε }.

Improved system integration for integrated gasification combined cycle (IGCC) systems.

PubMed

Frey, H Christopher; Zhu, Yunhua

2006-03-01

Integrated gasification combined cycle (IGCC) systems are a promising technology for power generation. They include an air separation unit (ASU), a gasification system, and a gas turbine combined cycle power block, and feature competitive efficiency and lower emissions compared to conventional power generation technology. IGCC systems are not yet in widespread commercial use and opportunities remain to improve system feasibility via improved process integration. A process simulation model was developed for IGCC systems with alternative types of ASU and gas turbine integration. The model is applied to evaluate integration schemes involving nitrogen injection, air extraction, and combinations of both, as well as different ASU pressure levels. The optimal nitrogen injection only case in combination with an elevated pressure ASU had the highest efficiency and power output and approximately the lowest emissions per unit output of all cases considered, and thus is a recommended design option. The optimal combination of air extraction coupled with nitrogen injection had slightly worse efficiency, power output, and emissions than the optimal nitrogen injection only case. Air extraction alone typically produced lower efficiency, lower power output, and higher emissions than all other cases. The recommended nitrogen injection only case is estimated to provide annualized cost savings compared to a nonintegrated design. Process simulation modeling is shown to be a useful tool for evaluation and screening of technology options.

Using the Global Environment Facility for developing Integrated Conservation and Development (ICAD) models -- Papua New Guinea`s Biodiversity Conservation Management Programme

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kula, G.; Jefferies, B.

1995-03-01

The unprecedented level of support that has been pledged to strengthen Government of Papua New Guinea (GoPNG) biodiversity conservation initiatives has re-identified an important fact that technical and infrastructure support must be complemented by programs that provide realistic opportunities for developing national capacity. Indications are that the next five years will present a range of challenging opportunities for the department to move from the intensive period of planning, which has been the focus of attention during the first phase of the National Forestry and Conservation Action Programme (NFCAP), into a sustained period of policy and project application. This paper examinesmore » processes under which strengthening programs contribute to national development objectives and complement accomplishment of the Department of Environment and Conservation Strategic Plan. An overview of the Global Environment Facility-Integrated Conservation and Development (ICAD) Project and coordination effort that are being made for biodiversity conservation projects in Papua New Guinea, are addressed.« less

Crowdsourcing conservation: The role of citizen science in securing a future for seagrass.

PubMed

Jones, Benjamin L; Unsworth, Richard K F; McKenzie, Len J; Yoshida, Rudi L; Cullen-Unsworth, Leanne C

2017-11-11

Seagrass meadows are complex social-ecological systems. Understanding seagrass meadows demands a fresh approach integrating "the human dimension". Citizen science is widely acknowledged for providing significant contributions to science, education, society and policy. Although the take up of citizen science in the marine environment has been slow, the need for such methods to fill vast information gaps is arguably great. Seagrass meadows are easy to access and provide an example of where citizen science is expanding. Technological developments have been pivotal to this, providing new opportunities for citizens to engage with seagrass. The increasing use of online tools has created opportunities to collect and submit as well as help process and analyse data. Citizen science has helped researchers integrate scientific and local knowledge and engage communities to implement conservation measures. Here we use a selection of examples to demonstrate how citizen science can secure a future for seagrass. Copyright © 2017 Elsevier Ltd. All rights reserved.

Sustainable Urban Waters: Opportunities to Integrate Environmental Protection in Multi-objective Projects

EPA Science Inventory

Abstract: Nonpoint source pollution is an ongoing challenge for environmental agencies who seek to protect waters of the U.S. Urban stream and waterfront redevelopment projects present opportunities to achieve integrated environmental, economic, and social benefits in urban water...

Integrating Sustainability as a Learning Tool

ERIC Educational Resources Information Center

Shiver, Steven M.; Dale, John R.

2011-01-01

Implementation of user interfaces designed to explain sustainable practices and provide opportunities for integration into curriculum include the new Renton Secondary Learning Center near Seattle, Washington. The Renton Secondary Learning Center (RSLC) builds upon a "Continuum of Services" to expand offerings and opportunities for…

The Role of Interpersonal Connection, Personal Narrative, and Metacognition in Integrative Psychotherapy for Schizophrenia: A Case Report.

PubMed

Hamm, Jay A; Leonhardt, Bethany L

2016-02-01

The recovery movement has not only challenged traditional pessimism regarding schizophrenia but also presented opportunities for the possibilities for psychotherapy for people with the disorder. Though in the past psychotherapy models were often pitted against one another, recently there have been emergent reports of a range of integrative models sharing an emphasis on recovery and a number of conceptual elements. These shared elements include attention to the importance of interpersonal processes, personal narrative, and metacognition, with interest in their role in not only the disorder but also the processes by which people pursue recovery. This article explores one application of this framework in the psychotherapy of a woman with prolonged experience of schizophrenia and significant functional impairments. © 2015 Wiley Periodicals, Inc.

Heterogeneous integration of low-temperature metal-oxide TFTs

NASA Astrophysics Data System (ADS)

Schuette, Michael L.; Green, Andrew J.; Leedy, Kevin D.; McCandless, Jonathan P.; Jessen, Gregg H.

2017-02-01

The breadth of circuit fabrication opportunities enabled by metal-oxide thin-film transistors (MO-TFTs) is unprecedented. Large-area deposition techniques and high electron mobility are behind their adoption in the display industry, and substrate agnosticism and low process temperatures enabled the present wave of flexible electronics research. Reports of circuits involving complementaryMO-TFTs, oxide-organic hybrid combinations, and even MO-TFTs integrated onto Si LSI back end of line interconnects demonstrate this technology's utility in 2D and 3D monolithic heterogeneous integration (HI). In addition to a brief literature review focused on functional HI between MO-TFTs and a variety of dissimilar active devices, we share progress toward integrating MO-TFTs with compound semiconductor devices, namely GaN HEMTs. A monolithically integrated cascode topology was used to couple a HEMT's >200 V breakdown characteristic with the gate driving characteristic of an IGZO TFT, effectively shifting the HEMT threshold voltage from -3 V to +1 V.

Passport-PeopleSoft integration for HANDI 2000 business management system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wilson, D.

The integration between the PeopleSoft applications and Passport modules are accomplished with an off the shelf package developed by lNDUS. The product was updated to the PeopleSoft Release 7.O. The Integration product interacts with data from multiple products within Passport and PeopleSoft. For 10/l/98 the Integration will interlace between the following: (1) PassPort Accounts Payable, Contract Management, Inventory Management, Purchasing; and (2) PeopleSoft General Ledger, Project Costing, Human Resources, Payroll. The current supply systems and financial systems interact with each other via multiple custom interfaces. Data integrity and Y2K issues were some of the driving factors in replacement of thesemore » systems. The new systems allow FDH the opportunity to change the current business processes to go to a best business practice that the commercial off the shelf software was adopted.« less

The Massachusetts HIV, hepatitis, addiction services integration (HHASI) experience: responding to the comprehensive needs of individuals with co-occurring risks and conditions.

PubMed

Hoffman, Heidi L; Castro-Donlan, Carolyn A; Johnson, Victoria M; Church, Daniel R

2004-01-01

Categorical funding mechanisms traditionally used to fund public health programs are a challenge to providers serving individuals with complex needs that often span multiple service areas. Integration--a formalized, collaborative process among service systems--responds to the challenge by decreasing fragmentation of care and improving coordination. In 2000, the Massachusetts Department of Public Health (MDPH) received a one-year planning grant from the federal Substance Abuse and Mental Health Services Administration (SAMHSA) to evaluate opportunities for integrating HIV/AIDS programs and substance abuse treatment programs. The project was later expanded to include viral hepatitis programming. Outcomes include the development of a strategic plan, joint procurement initiatives, and an ongoing commitment to sustain inter-bureau integration efforts, even in the face of substantial budget reductions. Integrated approaches can promote greater efficiency, improving communication and coordination among clients, providers, and government funding agencies.

UAV-Based Hyperspectral Remote Sensing for Precision Agriculture: Challenges and Opportunities

NASA Astrophysics Data System (ADS)

Angel, Y.; Parkes, S. D.; Turner, D.; Houborg, R.; Lucieer, A.; McCabe, M.

2017-12-01

Modern agricultural production relies on monitoring crop status by observing and measuring variables such as soil condition, plant health, fertilizer and pesticide effect, irrigation and crop yield. Managing all of these factors is a considerable challenge for crop producers. As such, providing integrated technological solutions that enable improved diagnostics of field condition to maximize profits, while minimizing environmental impacts, would be of much interest. Such challenges can be addressed by implementing remote sensing systems such as hyperspectral imaging to produce precise biophysical indicator maps across the various cycles of crop development. Recent progress in unmanned aerial vehicles (UAVs) have advanced traditional satellite-based capabilities, providing a capacity for high-spatial, spectral and temporal response. However, while some hyperspectral sensors have been developed for use onboard UAVs, significant investment is required to develop a system and data processing workflow that retrieves accurately georeferenced mosaics. Here we explore the use of a pushbroom hyperspectral camera that is integrated on-board a multi-rotor UAV system to measure the surface reflectance in 272 distinct spectral bands across a wavelengths range spanning 400-1000 nm, and outline the requirement for sensor calibration, integration onto a stable UAV platform enabling accurate positional data, flight planning, and development of data post-processing workflows for georeferenced mosaics. The provision of high-quality and geo-corrected imagery facilitates the development of metrics of vegetation health that can be used to identify potential problems such as production inefficiencies, diseases and nutrient deficiencies and other data-streams to enable improved crop management. Immense opportunities remain to be exploited in the implementation of UAV-based hyperspectral sensing (and its combination with other imaging systems) to provide a transferable and scalable integrated framework for crop growth monitoring and yield prediction. Here we explore some of the challenges and issues in translating the available technological capacity into a useful and useable image collection and processing flow-path that enables these potential applications to be better realized.

Integrating critical thinking and evidence-based dentistry across a four-year dental curriculum: a model for independent learning.

PubMed

Marshall, Teresa A; Straub-Morarend, Cheryl L; Handoo, Nidhi; Solow, Catherine M; Cunningham-Ford, Marsha A; Finkelstein, Michael W

2014-03-01

Introducing critical thinking and evidence-based dentistry (EBD) content into an established dental curriculum can be a difficult and challenging process. Over the past three years, the University of Iowa College of Dentistry has developed and implemented a progressive four-year integrated critical thinking and EBD curriculum. The objective of this article is to describe the development and implementation process to make it available as a model for other dental schools contemplating introduction of critical thinking and EBD into their curricula. The newly designed curriculum built upon an existing problem-based learning foundation, which introduces critical thinking and the scientific literature in the D1 year, in order to expose students to the rationale and resources for practicing EBD in the D2 and D3 years and provide opportunities to practice critical thinking and apply the EBD five-step process in the D2, D3, and D4 years. All curricular content is online, and D3 and D4 EBD activities are integrated within existing clinical responsibilities. The curricular content, student resources, and student activities are described.

An innovative large scale integration of silicon nanowire-based field effect transistors

NASA Astrophysics Data System (ADS)

Legallais, M.; Nguyen, T. T. T.; Mouis, M.; Salem, B.; Robin, E.; Chenevier, P.; Ternon, C.

2018-05-01

Since the early 2000s, silicon nanowire field effect transistors are emerging as ultrasensitive biosensors while offering label-free, portable and rapid detection. Nevertheless, their large scale production remains an ongoing challenge due to time consuming, complex and costly technology. In order to bypass these issues, we report here on the first integration of silicon nanowire networks, called nanonet, into long channel field effect transistors using standard microelectronic process. A special attention is paid to the silicidation of the contacts which involved a large number of SiNWs. The electrical characteristics of these FETs constituted by randomly oriented silicon nanowires are also studied. Compatible integration on the back-end of CMOS readout and promising electrical performances open new opportunities for sensing applications.

Gravitational Influences on the Growth of Polydiacetylene Films by Ultraviolet Solution Polymerization

NASA Technical Reports Server (NTRS)

Frazier, Donald O.

2000-01-01

Technically, the field of integrated optics using organic/polymer materials as a new means of information processing, has emerged as of vital importance to optical computers, optical switching, optical communications, the defense industry, etc. The goal is to replace conventional electronic integrated circuits and wires by equivalent miniaturized optical integrated circuits and fibers, offering larger bandwidths, more compactness and reliability, immunity to electromagnetic interference and less cost. From the Code E perspective, this research area represents an opportunity to marry "front-line" education in science and technology with national scientific and technological interests while maximizing human resources utilization. This can be achieved by the development of untapped resources for scientific research - such as minorities, women, and universities traditionally uninvolved in scientific research.

Cross-scale phenological data integration to benefit resource management and monitoring

USGS Publications Warehouse

Richardson, Andrew D.; Weltzin, Jake F.; Morisette, Jeffrey T.

2017-01-01

Climate change is presenting new challenges for natural resource managers charged with maintaining sustainable ecosystems and landscapes. Phenology, a branch of science dealing with seasonal natural phenomena (bird migration or plant flowering in response to weather changes, for example), bridges the gap between the biosphere and the climate system. Phenological processes operate across scales that span orders of magnitude—from leaf to globe and from days to seasons—making phenology ideally suited to multiscale, multiplatform data integration and delivery of information at spatial and temporal scales suitable to inform resource management decisions.A workshop report: Workshop held June 2016 to investigate opportunities and challenges facing multi-scale, multi-platform integration of phenological data to support natural resource management decision-making.

Precision cast vs. wrought superalloys

NASA Technical Reports Server (NTRS)

Tien, J. K.; Borofka, J. C.; Casey, M. E.

1986-01-01

While cast polycrystalline superalloys recommend themselves in virtue of better 'buy-to-fly' ratios and higher strengthening gamma-prime volume fractions than those of wrought superalloys, the expansion of their use into such critical superalloy applications as gas turbine hot section components has been slowed by insufficient casting process opportunities for microstructural control. Attention is presently drawn, however, to casting process developments facilitating the production of defect-tolerant superalloy castings having improved fracture reliability. Integrally bladed turbine wheel and thin-walled turbine exhaust case near-net-shape castings have been produced by these means.

Application of vacuum reduction and chlorinated distillation to enrich and prepare pure germanium from coal fly ash.

PubMed

Zhang, Lingen; Xu, Zhenming

2017-01-05

Germanium, as strategic reserve metal, plays critical role in high-tech industry. However, a contradiction of increasing consumption and scarcity of germanium resource is becoming more and more prominent. This paper proposed an integrated process to recycle germanium from coal fly ash. This technological process mainly consisted of two procedures: vacuum reduction with the purposes of enriching germanium and chlorinated distillation with the purposes of purifying germanium. Several highlights are summarized as follows: (i) Separation principle and reaction mechanism were discussed to understand this integrated process. (ii) Optimum designs and product analysis were developed to guide industrial recycling. The appropriate parameters for vacuum reduction process on the basis of response surface methodology (RSM) were 920.53°C and 259.63Pa, with 16.64wt.% reductant, and for the chlorinated distillation process, adding 8mol/l HCl and L/S 7, 8wt.% MnO 2 . The global recovery rate of germanium was 83.48±0.36% for the integrated process. (iii) This process overcomes the shortages of traditional process and shows its efficiency and environmental performance. It is significant in accordance with the "Reduce, Reuse and Recycle Principle" for solid waste and further provides a new opportunity for germanium recovery from waste by environment-friendly way. Copyright © 2016. Published by Elsevier B.V.

Individual psychotherapy for schizophrenia: trends and developments in the wake of the recovery movement.

PubMed

Hamm, Jay A; Hasson-Ohayon, Ilanit; Kukla, Marina; Lysaker, Paul H

2013-01-01

Although the role and relative prominence of psychotherapy in the treatment of schizophrenia has fluctuated over time, an analysis of the history of psychotherapy for schizophrenia, focusing on findings from the recovery movement, reveals recent trends including the emergence of the development of integrative psychotherapy approaches. The authors suggest that the recovery movement has revealed limitations in traditional approaches to psychotherapy, and has provided opportunities for integrative approaches to emerge as a mechanism for promoting recovery in persons with schizophrenia. Five approaches to integrative psychotherapy for persons with schizophrenia are presented, and a shared conceptual framework that allows these five approaches to be compatible with one another is proposed. The conceptual framework is consistent with theories of recovery and emphasizes interpersonal attachment, personal narrative, and metacognitive processes. Implications for future research on integrative psychotherapy are considered.

Lost in Translation: the Case for Integrated Testing

NASA Technical Reports Server (NTRS)

Young, Aaron

2017-01-01

The building of a spacecraft is complex and often involves multiple suppliers and companies that have their own designs and processes. Standards have been developed across the industries to reduce the chances for critical flight errors at the system level, but the spacecraft is still vulnerable to the introduction of critical errors during integration of these systems. Critical errors can occur at any time during the process and in many cases, human reliability analysis (HRA) identifies human error as a risk driver. Most programs have a test plan in place that is intended to catch these errors, but it is not uncommon for schedule and cost stress to result in less testing than initially planned. Therefore, integrated testing, or "testing as you fly," is essential as a final check on the design and assembly to catch any errors prior to the mission. This presentation will outline the unique benefits of integrated testing by catching critical flight errors that can otherwise go undetected, discuss HRA methods that are used to identify opportunities for human error, lessons learned and challenges over ownership of testing will be discussed.

Learning Bridge: Curricular Integration of Didactic and Experiential Education

PubMed Central

Arendt, Cassandra S.; Cawley, Pauline; Buhler, Amber V.; Elbarbry, Fawzy; Roberts, Sigrid C.

2010-01-01

Objectives To assess the impact of a program to integrate introductory pharmacy practice experiences with pharmaceutical science topics by promoting active learning, self-directed learning skills, and critical-thinking skills. Design The Learning Bridge, a curriculum program, was created to better integrate the material first-year (P1) students learned in pharmaceutical science courses into their introductory pharmacy practice experiences. Four Learning Bridge assignments required students to interact with their preceptors and answer questions relating to the pharmaceutical science material concurrently covered in their didactic courses. Assessment Surveys of students and preceptors were conducted to measure the effectiveness of the Learning Bridge process. Feedback indicated the Learning Bridge promoted students' interaction with their preceptors as well as development of active learning, self-directed learning, and critical-thinking skills. Students also indicated that the Learning Bridge assignments increased their learning, knowledge of drug information, and comprehension of relevant data in package inserts. Conclusion The Learning Bridge process integrated the didactic and experiential components of the curriculum, enhancing student learning in both areas, and offered students educational opportunities to interact more with their preceptors. PMID:20498741

Integrating Opportunities: Applied Interdisciplinary Research in Undergraduate Geography and Geology Education

ERIC Educational Resources Information Center

Viertel, David C.; Burns, Diane M.

2012-01-01

Unique integrative learning approaches represent a fundamental opportunity for undergraduate students and faculty alike to combine interdisciplinary methods with applied spatial research. Geography and geoscience-related disciplines are particularly well-suited to adapt multiple methods within a holistic and reflective mentored research paradigm.…

How Philadelphia is Integrating Climate Science and Policy: Changing Capital Planning Processes and Developing Flood-Depth Tools

NASA Astrophysics Data System (ADS)

Bhat, C.; Dix, B.; Choate, A.; Wong, A.; Asam, S.; Schultz, P. A.

2016-12-01

Policy makers can implement more effective climate change adaptation programs if they are provided with two tools: accessible information on the impacts that they need to prepare for, and clear guidance on how to integrate climate change considerations into their work. This presentation will highlight recent and ongoing efforts at the City of Philadelphia to integrate climate science into their decision-making. These efforts include developing a climate change information visualization tool, climate change risk assessments across the city, and processes to integrate climate change into routine planning and budgeting practices. The goal of these efforts is to make climate change science highly targeted to decision maker needs, non-political, easily accessible, and actionable. While sea level rise inundation maps have been available to communities for years, the maps do not effectively communicate how the design of a building or a piece of infrastructure would need to be modified to protect it. The Philadelphia Flood Risk Viewer is an interactive planning tool that allows Philadelphia to identify projected depths of flooding for any location within the City, for a variety of sea level rise and storm surge scenarios. Users can also determine whether a location is located in a FEMA floodplain. By having access to information on the projected depth of flooding at a given location, the City can determine what flood protection measures may be effective, or even inform the long-term viability of developing a particular area. With an understanding of climate vulnerabilities, cities have the opportunity to make smart, climate-resilient investments with their capital budgets that will yield multiple benefits for years to come. Few, however, have established protocols for doing so. Philadelphia, with support from ICF, developed a guidance document that identifies recommendations for integrating climate change considerations throughout the Capital Program and capital budgeting process. For each recommendation, the guidance also provides supplemental resources and information to make the recommendations actionable. Philadelphia is applying the guidance in their FY 2017 capital planning activities and taking advantage of opportunities to grow stronger in the face of climate change.

Asthma in the community: Designing instruction to help students explore scientific dilemmas that impact their lives

NASA Astrophysics Data System (ADS)

Tate, Erika Dawn

School science instruction that connects to students' diverse home, cultural, or linguistic experiences can encourage lifelong participation in the scientific dilemmas that impact students' lives. This dissertation seeks effective ways to support high school students as they learn complex science topics and use their knowledge to transform their personal and community environments. Applying the knowledge integration perspective, I collaborated with education, science, and community partners to design a technology enhanced science module, Improving Your Community's Asthma Problem. This exemplar community science curriculum afforded students the opportunity to (a) investigate a local community health issue, (b) interact with relevant evidence related to physiology, clinical management, and environmental risks, and (c) construct an integrated understanding of the asthma problem in their community. To identify effective instructional scaffolds that engage students in the knowledge integration process and prepare them to participate in community science, I conducted 2 years of research that included 5 schools, 10 teachers, and over 500 students. This dissertation reports on four studies that analyzed student responses on pre-, post-, and embedded assessments. Researching across four design stages, the iterative design study investigated how to best embed the visualizations of the physiological processes breathing, asthma attack, and the allergic immune response in an inquiry activity and informed evidence-based revisions to the module. The evaluation study investigated the impact of this revised Asthma module across multiple classrooms and differences in students' prior knowledge. Combining evidence of student learning from the iterative and evaluation studies with classroom observations and teacher interviews, the longitudinal study explored the impact of teacher practices on student learning in years 1 and 2. In the final chapter, I studied how the Asthma module and students' local community influenced students as they integrated their ideas related to perspectives, evidence use, the consideration of tradeoffs, and localization to construct explanations and decision justifications regarding their community's asthma problem. In the end, this dissertation offers evidence that informs the future design of community science instruction that successfully engages students in the knowledge integration process and has implications for creating multiple opportunities for students to meaningfully participate in community science.

Comprehensive profiling of retroviral integration sites using target enrichment methods from historical koala samples without an assembled reference genome

PubMed Central

Alquezar-Planas, David E.; Ishida, Yasuko; Courtiol, Alexandre; Timms, Peter; Johnson, Rebecca N.; Lenz, Dorina; Helgen, Kristofer M.; Roca, Alfred L.; Hartman, Stefanie

2016-01-01

Background. Retroviral integration into the host germline results in permanent viral colonization of vertebrate genomes. The koala retrovirus (KoRV) is currently invading the germline of the koala (Phascolarctos cinereus) and provides a unique opportunity for studying retroviral endogenization. Previous analysis of KoRV integration patterns in modern koalas demonstrate that they share integration sites primarily if they are related, indicating that the process is currently driven by vertical transmission rather than infection. However, due to methodological challenges, KoRV integrations have not been comprehensively characterized. Results. To overcome these challenges, we applied and compared three target enrichment techniques coupled with next generation sequencing (NGS) and a newly customized sequence-clustering based computational pipeline to determine the integration sites for 10 museum Queensland and New South Wales (NSW) koala samples collected between the 1870s and late 1980s. A secondary aim of this study sought to identify common integration sites across modern and historical specimens by comparing our dataset to previously published studies. Several million sequences were processed, and the KoRV integration sites in each koala were characterized. Conclusions. Although the three enrichment methods each exhibited bias in integration site retrieval, a combination of two methods, Primer Extension Capture and hybridization capture is recommended for future studies on historical samples. Moreover, identification of integration sites shows that the proportion of integration sites shared between any two koalas is quite small. PMID:27069793

Common Badging and Access Control System (CBACS)

NASA Technical Reports Server (NTRS)

Baldridge, Tim

2005-01-01

The goals of the project are: Achieve high business value through a common badging and access control system that integrates with smart cards. Provide physical (versus logical) deployment of smart cards initially. Provides a common consistent and reliable environment into which to release the smart card. Gives opportunity to develop agency-wide consistent processes, practices and policies. Enables enterprise data capture and management. Promotes data validation prior to SC issuance.

Human Systems Integration Synthesis Model for Ship Design

DTIC Science & Technology

2012-09-01

this process. Specifically, I thank Dr. Paulo for both planting the seed that led to this thesis and giving me the opportunity to participate in the...manufacturing systems, refineries, and nuclear power plants must also rely on up-to-date knowledge of situation parameters and any patterns among...safety hazards were many due to exposure to toxic fuel, increased probability of fires, and steam plant explosions. In order to address the

Cognitive Styles and the Social Order. Final Report, Part II. O.E.O. Study B00-5135, "Thought, Race, and Opportunity."

ERIC Educational Resources Information Center

TenHouten, Warren D.

This report presents data developed for testing the theory that there are social processes which result in differing cognitive styles for subdominant and dominant social groups. The results of surveys of black and white persons in an urban area, of white rural farmers, and Hopi Indians are presented. The research attempts to integrate data and…

An approach to industrial water conservation--a case study involving two large manufacturing companies based in Australia.

PubMed

Agana, Bernard A; Reeve, Darrell; Orbell, John D

2013-01-15

This study presents the application of an integrated water management strategy at two large Australian manufacturing companies that are contrasting in terms of their respective products. The integrated strategy, consisting of water audit, pinch analysis and membrane process application, was deployed in series to systematically identify water conservation opportunities. Initially, a water audit was deployed to completely characterize all water streams found at each production site. This led to the development of a water balance diagram which, together with water test results, served as a basis for subsequent enquiry. After the water audit, commercially available water pinch software was utilized to identify possible water reuse opportunities, some of which were subsequently implemented on site. Finally, utilizing a laboratory-scale test rig, membrane processes such as UF, NF and RO were evaluated for their suitability to treat the various wastewater streams. The membranes tested generally showed good contaminant rejection rates, slow flux decline rates, low energy usage and were well suited for treatment of specific wastewater streams. The synergy between the various components of this strategy has the potential to reduce substantial amounts of Citywater consumption and wastewater discharge across a diverse range of large manufacturing companies. Crown Copyright © 2012. Published by Elsevier Ltd. All rights reserved.

Breaking barriers: a competency-based framework for promoting the integration of the pediatrician's education.

PubMed

Naghettini, Alessandra V; Bollela, Valdes R; Costa, Nilce M S C; Salgado, Luciana M R

2011-01-01

To describe the process of integration and revision of a pediatric program curriculum which resulted in the creation of a competency-based framework recommended in the Brazilian National Curricular Guidelines. Quali-quantitative analysis of an intervention evaluating the students and professors' perception of the pediatric program curriculum (focus groups and semi-structured interviews). Results were discussed during teaching development workshops. A competency-based framework was suggested for the pediatric program from the 3rd to the 6th year. The new curriculum was approved, implemented, and reevaluated six months later. Twelve students (12%) from the 3rd to the 6th year participated in the focus groups, and 11 professors (78.5%) answered the questionnaire. Most participants reported lack of integration among the courses, lack of knowledge about the learning goals of the internships, few opportunities of practice, and predominance of theoretical evaluation. In the training workshops, a competency-based curriculum was created after pediatrics and collective health professors reached an agreement. The new curriculum was focused on general competency, learning goals, opportunities available to learn these goals, and evaluation system. After six months, 93% (104/112) of students and 79% (11/14) of professors reported greater integration of the program and highlighted the inclusion of the clinical performance evaluation. The collective creation of a competency-based curriculum promoted higher satisfaction of students and professors. After being implemented, the new curriculum was considered to integrate the teaching practices and contents, improving the quality of the clinical performance evaluation.

Financial incentives for disease management programmes and integrated care in German social health insurance.

PubMed

Greb, Stefan; Focke, Axel; Hessel, Franz; Wasem, Jürgen

2006-10-01

As a result of recent health care reforms sickness funds and health care providers in German social health insurance face increased financial incentives for implementing disease management and integrated care. Sickness funds receive higher payments form the risk adjustment system if they set up certified disease management programmes and induce patients to enrol. If health care providers establish integrated care projects they are able to receive extra-budgetary funding. As a consequence, the number of certified disease management programmes and the number of integrated care contracts is increasing rapidly. However, contracts about disease management programmes between sickness funds and health care providers are highly standardized. The overall share of health care expenses spent on integrated care still is very low. Existing integrated care is mostly initiated by hospitals, is based on only one indication and is not fully integrated. However, opportunity to invest in integrated care may open up innovative processes, which generate considerable productivity gains. What is more, integrated care may serve as gateway for the introduction of more widespread selective contracting.

Integrated Risk Management Within NASA Programs/Projects

NASA Technical Reports Server (NTRS)

Connley, Warren; Rad, Adrian; Botzum, Stephen

2004-01-01

As NASA Project Risk Management activities continue to evolve, the need to successfully integrate risk management processes across the life cycle, between functional disciplines, stakeholders, various management policies, and within cost, schedule and performance requirements/constraints become more evident and important. Today's programs and projects are complex undertakings that include a myriad of processes, tools, techniques, management arrangements and other variables all of which must function together in order to achieve mission success. The perception and impact of risk may vary significantly among stakeholders and may influence decisions that may have unintended consequences on the project during a future phase of the life cycle. In these cases, risks may be unintentionally and/or arbitrarily transferred to others without the benefit of a comprehensive systemic risk assessment. Integrating risk across people, processes, and project requirements/constraints serves to enhance decisions, strengthen communication pathways, and reinforce the ability of the project team to identify and manage risks across the broad spectrum of project management responsibilities. The ability to identify risks in all areas of project management increases the likelihood a project will identify significant issues before they become problems and allows projects to make effective and efficient use of shrinking resources. By getting a total team integrated risk effort, applying a disciplined and rigorous process, along with understanding project requirements/constraints provides the opportunity for more effective risk management. Applying an integrated approach to risk management makes it possible to do a better job at balancing safety, cost, schedule, operational performance and other elements of risk. This paper will examine how people, processes, and project requirements/constraints can be integrated across the project lifecycle for better risk management and ultimately improve the chances for mission success.

Use of new scientific developments in regulatory risk assessments: challenges and opportunities.

PubMed

Tarazona, Jose V

2013-07-01

Since the 1990s, science based ecological risk assessments constitute an essential tool for supporting decision making in the regulatory context. Using the European REACH Regulation as example, this article presents the challenges and opportunities for new scientific developments within the area of chemical control and environmental protection. These challenges can be sorted out in 3 main related topics (sets). In the short term, the challenges are directly associated with the regulatory requirements, required for facilitating a scientifically sound implementation of the different obligations for industry and authorities. It is important to mention that although the actual tools are different due to the regulatory requirements, the basic needs are still the same as those addressed in the early 1990s: understanding the ecological relevance of the predicted effects, including the uncertainty, and facilitating the link with the socio-economic assessment. The second set of challenges covers the opportunities for getting an added value from the regulatory efforts. The information compiled through REACH registration and notification processes is analyzed as source for new integrative developments for assessing the combined chemical risk at the regional level. Finally, the article discusses the challenge of inverting the process and developing risk assessment methods focusing on the receptor, the individual or ecosystem, instead of on the stressor or source. These approaches were limited in the past due to the lack of information, but the identification and dissemination of standard information, including uses, manufacturing sites, physical-chemical, environmental, ecotoxicological, and toxicological properties as well as operational conditions and risk management measures for thousands of chemicals, combined by the knowledge gathered through large scale monitoring programs and spatial information systems is generating new opportunities. The challenge is liking predictions and measured data in an integral "-omic type" approach, considering collectively data from different sources and offering a complete assessment of the chemical risk of individuals and ecosystems, with new conceptual approaches that could be defined as "risk-omics based" paradigms and models. Copyright © 2013 SETAC.

Estrogen Effects on Wound Healing

PubMed Central

Horng, Huann-Cheng; Chang, Wen-Hsun; Yeh, Chang-Ching; Huang, Ben-Shian; Chang, Chia-Pei; Chen, Yi-Jen; Tsui, Kuan-Hao

2017-01-01

Wound healing is a physiological process, involving three successive and overlapping phases—hemostasis/inflammation, proliferation, and remodeling—to maintain the integrity of skin after trauma, either by accident or by procedure. Any disruption or unbalanced distribution of these processes might result in abnormal wound healing. Many molecular and clinical data support the effects of estrogen on normal skin homeostasis and wound healing. Estrogen deficiency, for example in postmenopausal women, is detrimental to wound healing processes, notably inflammation and re-granulation, while exogenous estrogen treatment may reverse these effects. Understanding the role of estrogen on skin might provide further opportunities to develop estrogen-related therapy for assistance in wound healing. PMID:29099810

Ceramic Integration Technologies for Aerospace and Energy Systems: Technical Challenges and Opportunities

NASA Technical Reports Server (NTRS)

Singh, Mrityunjay

2007-01-01

Ceramic integration technology has been recognized as an enabling technology for the implementation of advanced ceramic systems in a number of high-temperature applications in aerospace, power generation, nuclear, chemical, and electronic industries. Various ceramic integration technologies (joining, brazing, attachments, repair, etc.) play a role in fabrication and manufacturing of large and complex shaped parts of various functionalities. However, the development of robust and reliable integrated systems with optimum performance requires the understanding of many thermochemical and thermomechanical factors, particularly for high temperature applications. In this presentation, various challenges and opportunities in design, fabrication, and testing of integrated similar (ceramic-ceramic) and dissimilar (ceramic-metal) material systems will be discussed. Experimental results for bonding and integration of SiC based LDI fuel injector, high conductivity C/C composite based heat rejection system, solid oxide fuel cells system, ultra high temperature ceramics for leading edges, and ceramic composites for thermostructural applications will be presented. Potential opportunities and need for the development of innovative design philosophies, approaches, and integrated system testing under simulated application conditions will also be discussed.

Lab-on-CMOS Integration of Microfluidics and Electrochemical Sensors

PubMed Central

Huang, Yue; Mason, Andrew J.

2013-01-01

This paper introduces a CMOS-microfluidics integration scheme for electrochemical microsystems. A CMOS chip was embedded into a micro-machined silicon carrier. By leveling the CMOS chip and carrier surface to within 100 nm, an expanded obstacle-free surface suitable for photolithography was achieved. Thin film metal planar interconnects were microfabricated to bridge CMOS pads to the perimeter of the carrier, leaving a flat and smooth surface for integrating microfluidic structures. A model device containing SU-8 microfluidic mixers and detection channels crossing over microelectrodes on a CMOS integrated circuit was constructed using the chip-carrier assembly scheme. Functional integrity of microfluidic structures and on-CMOS electrodes was verified by a simultaneous sample dilution and electrochemical detection experiment within multi-channel microfluidics. This lab-on-CMOS integration process is capable of high packing density, is suitable for wafer-level batch production, and opens new opportunities to combine the performance benefits of on-CMOS sensors with lab-on-chip platforms. PMID:23939616

Lab-on-CMOS integration of microfluidics and electrochemical sensors.

PubMed

Huang, Yue; Mason, Andrew J

2013-10-07

This paper introduces a CMOS-microfluidics integration scheme for electrochemical microsystems. A CMOS chip was embedded into a micro-machined silicon carrier. By leveling the CMOS chip and carrier surface to within 100 nm, an expanded obstacle-free surface suitable for photolithography was achieved. Thin film metal planar interconnects were microfabricated to bridge CMOS pads to the perimeter of the carrier, leaving a flat and smooth surface for integrating microfluidic structures. A model device containing SU-8 microfluidic mixers and detection channels crossing over microelectrodes on a CMOS integrated circuit was constructed using the chip-carrier assembly scheme. Functional integrity of microfluidic structures and on-CMOS electrodes was verified by a simultaneous sample dilution and electrochemical detection experiment within multi-channel microfluidics. This lab-on-CMOS integration process is capable of high packing density, is suitable for wafer-level batch production, and opens new opportunities to combine the performance benefits of on-CMOS sensors with lab-on-chip platforms.

The Hitchhiker's Guide to I&T

NASA Technical Reports Server (NTRS)

Wright, Michael R.

1999-01-01

With over two dozen missions since the first in 1986, the Hitchhiker project has a reputation for providing quick-reaction, low-cost flight services for Shuttle Small Payloads Project (SSPP) customers. Despite the successes, several potential improvements in customer payload integration and test (I&T) deserve consideration. This paper presents suggestions to Hitchhiker customers on how to help make the I&T process run smoother. Included are: customer requirements and interface definition, pre-integration test and evaluation, configuration management, I&T overview and planning, problem mitigation, and organizational communication. In this era of limited flight opportunities and new ISO-based requirements, issues such as these have become more important than ever.

Entrepreneurship management in health services: an integrative model.

PubMed

Guo, Kristina L

2006-01-01

This research develops an integrated systems model of entrepreneurship management as a method for achieving health care organizational survival and growth. Specifically, it analyzes current health care environment challenges, identifies roles of managers and discusses organizational theories that are relevant to the health care environment, outlines the role of entrepreneurship in health care, and describes the entrepreneurial manager in the entrepreneurial management process to produce desirable organizational outcomes. The study concludes that as current health care environment continues to show intense competition, entrepreneurial managers are responsible for creating innovations, managing change, investing in resources, and recognizing opportunities in the environment to increase organizational viability.

Integrating evidence-based interventions into client care plans.

PubMed

Doran, Diane; Carryer, Jennifer; Paterson, Jane; Goering, Paula; Nagle, Lynn; Kushniruk, Andre; Bajnok, Irmajean; Clark, Carrie; Srivastava, Rani

2009-01-01

Within the mental health care system, there is an opportunity to improve patient safety and the overall quality of care by integrating clinical practice guidelines with the care planning process through the use of information technology. Electronic assessment tools such as the Resident Assessment Inventory - Mental Health (RAI-MH) are widely used to identify the health care needs and outcomes of clients. In this knowledge translation initiative, an electronic care planning tool was enhanced to include evidence-based clinical interventions from schizophrenia guidelines. This paper describes the development of a mental health decision support prototype, a field test by clinicians, and user experiences with the application.

Inquiry-Based Integrated Science Education: Implementation of Local Content “Soil Washing” Project To Improve Junior High School Students’ Environmental Literacy

NASA Astrophysics Data System (ADS)

Syifahayu

2017-02-01

The study was conducted based on teaching and learning problems led by conventional method that had been done in the process of learning science. It gave students lack opportunities to develop their competence and thinking skills. Consequently, the process of learning science was neglected. Students did not have opportunity to improve their critical attitude and creative thinking skills. To cope this problem, the study was conducted using Project-Based Learning model through inquiry-based science education about environment. The study also used an approach called Sains Lingkungan and Teknologi masyarakat - “Saling Temas” (Environmental science and Technology in Society) which promoted the local content in Lampung as a theme in integrated science teaching and learning. The study was a quasi-experimental with pretest-posttest control group design. Initially, the subjects were given a pre-test. The experimental group was given inquiry learning method while the control group was given conventional learning. After the learning process, the subjects of both groups were given post-test. Quantitative analysis was performed using the Mann-Whitney U-test and also a qualitative descriptive. Based on the result, environmental literacy skills of students who get inquiry learning strategy, with project-based learning model on the theme soil washing, showed significant differences. The experimental group is better than the control group. Data analysis showed the p-value or sig. (2-tailed) is 0.000 <α = 0.05 with the average N-gain of experimental group is 34.72 and control group is 16.40. Besides, the learning process becomes more meaningful.

CB4-03: An Eye on the Future: A Review of Data Virtualization Techniques to Improve Research Analytics

PubMed Central

Richter, Jack; McFarland, Lela; Bredfeldt, Christine

2012-01-01

Background/Aims Integrating data across systems can be a daunting process. The traditional method of moving data to a common location, mapping fields with different formats and meanings, and performing data cleaning activities to ensure valid and reliable integration across systems can be both expensive and extremely time consuming. As the scope of needed research data increases, the traditional methodology may not be sustainable. Data Virtualization provides an alternative to traditional methods that may reduce the effort required to integrate data across disparate systems. Objective Our goal was to survey new methods in data integration, cloud computing, enterprise data management and virtual data management for opportunities to increase the efficiency of producing VDW and similar data sets. Methods Kaiser Permanente Information Technology (KPIT), in collaboration with the Mid-Atlantic Permanente Research Institute (MAPRI) reviewed methodologies in the burgeoning field of Data Virtualization. We identified potential strengths and weaknesses of new approaches to data integration. For each method, we evaluated its potential application for producing effective research data sets. Results Data Virtualization provides opportunities to reduce the amount of data movement required to integrate data sources on different platforms in order to produce research data sets. Additionally, Data Virtualization also includes methods for managing “fuzzy” matching used to match fields known to have poor reliability such as names, addresses and social security numbers. These methods could improve the efficiency of integrating state and federal data such as patient race, death, and tumors with internal electronic health record data. Discussion The emerging field of Data Virtualization has considerable potential for increasing the efficiency of producing research data sets. An important next step will be to develop a proof of concept project that will help us understand to benefits and drawbacks of these techniques.

Non-electrical-power temperature-time integrating sensor for RFID based on microfluidics

NASA Astrophysics Data System (ADS)

Schneider, Mike; Hoffmann, Martin

2011-06-01

The integration of RFID tags into packages offers the opportunity to combine logistic advantages of the technology with monitoring different parameters from inside the package at the same time. An essential demand for enhanced product safety especially in pharmacy or food industry is the monitoring of the time-temperature-integral. Thus, completely passive time-temperature-integrators (TTI) requiring no battery, microprocessor nor data logging devices are developed. TTI representing the sterilization process inside an autoclave system is a demanding challenge: a temperature of at least 120 °C have to be maintained over 45 minutes to assure that no unwanted organism remains. Due to increased temperature, the viscosity of a fluid changes and thus the speed of the fluid inside the channel increases. The filled length of the channel represents the time temperature integral affecting the system. Measurements as well as simulations allow drawing conclusions about the influence of the geometrical parameters of the system and provide the possibility of adaptation. Thus a completely passive sensor element for monitoring an integral parameter with waiving of external electrical power supply and data processing technology is demonstrated. Furthermore, it is shown how to adjust the specific TTI parameters of the sensor to different applications and needs by modifying the geometrical parameters of the system.

A MoTe2-based light-emitting diode and photodetector for silicon photonic integrated circuits.

PubMed

Bie, Ya-Qing; Grosso, Gabriele; Heuck, Mikkel; Furchi, Marco M; Cao, Yuan; Zheng, Jiabao; Bunandar, Darius; Navarro-Moratalla, Efren; Zhou, Lin; Efetov, Dmitri K; Taniguchi, Takashi; Watanabe, Kenji; Kong, Jing; Englund, Dirk; Jarillo-Herrero, Pablo

2017-12-01

One of the current challenges in photonics is developing high-speed, power-efficient, chip-integrated optical communications devices to address the interconnects bottleneck in high-speed computing systems. Silicon photonics has emerged as a leading architecture, in part because of the promise that many components, such as waveguides, couplers, interferometers and modulators, could be directly integrated on silicon-based processors. However, light sources and photodetectors present ongoing challenges. Common approaches for light sources include one or few off-chip or wafer-bonded lasers based on III-V materials, but recent system architecture studies show advantages for the use of many directly modulated light sources positioned at the transmitter location. The most advanced photodetectors in the silicon photonic process are based on germanium, but this requires additional germanium growth, which increases the system cost. The emerging two-dimensional transition-metal dichalcogenides (TMDs) offer a path for optical interconnect components that can be integrated with silicon photonics and complementary metal-oxide-semiconductors (CMOS) processing by back-end-of-the-line steps. Here, we demonstrate a silicon waveguide-integrated light source and photodetector based on a p-n junction of bilayer MoTe 2 , a TMD semiconductor with an infrared bandgap. This state-of-the-art fabrication technology provides new opportunities for integrated optoelectronic systems.

A MoTe2-based light-emitting diode and photodetector for silicon photonic integrated circuits

NASA Astrophysics Data System (ADS)

Bie, Ya-Qing; Grosso, Gabriele; Heuck, Mikkel; Furchi, Marco M.; Cao, Yuan; Zheng, Jiabao; Bunandar, Darius; Navarro-Moratalla, Efren; Zhou, Lin; Efetov, Dmitri K.; Taniguchi, Takashi; Watanabe, Kenji; Kong, Jing; Englund, Dirk; Jarillo-Herrero, Pablo

2017-12-01

One of the current challenges in photonics is developing high-speed, power-efficient, chip-integrated optical communications devices to address the interconnects bottleneck in high-speed computing systems. Silicon photonics has emerged as a leading architecture, in part because of the promise that many components, such as waveguides, couplers, interferometers and modulators, could be directly integrated on silicon-based processors. However, light sources and photodetectors present ongoing challenges. Common approaches for light sources include one or few off-chip or wafer-bonded lasers based on III-V materials, but recent system architecture studies show advantages for the use of many directly modulated light sources positioned at the transmitter location. The most advanced photodetectors in the silicon photonic process are based on germanium, but this requires additional germanium growth, which increases the system cost. The emerging two-dimensional transition-metal dichalcogenides (TMDs) offer a path for optical interconnect components that can be integrated with silicon photonics and complementary metal-oxide-semiconductors (CMOS) processing by back-end-of-the-line steps. Here, we demonstrate a silicon waveguide-integrated light source and photodetector based on a p-n junction of bilayer MoTe2, a TMD semiconductor with an infrared bandgap. This state-of-the-art fabrication technology provides new opportunities for integrated optoelectronic systems.

Commercial opportunities utilizing the International Space Station

NASA Astrophysics Data System (ADS)

Kearney, Michael E.; Mongan, Phil; Overmyer, Carolyn M.; Jackson, Kenneth

1998-01-01

The International Space Station (ISS) has the unique capability of providing a low-g environment for both short- and long-duration experimentation. This environment can provide a unique and competitive research capability to industry; but until recently, utilization of this environment by the private sector has been limited if not totally unavailable. NASA has recently expressed an interest in the commercial development of space and this is now an integral part of the Agency's enabling legislation through the Space Act. NASA's objective is to foster the use of the space environment for the development of commercial products and processes. Through alliances and agreements with several commercial companies and universities, SPACEHAB, Inc., has built a comprehensive package of services designed to provide low-cost reliable access to space for experimenters. These services provide opportunities to support engineering test beds for materials exposure analysis, to mitigate structural failures as observed on the Hubble Space Telescope; materials processing, remote sensing; space environment definition; and electronic experiments. The intent of this paper is to identify commercial opportunities for utilizing the International Space Station and provide examples of several facilities currently being designed and manufactured by commercial companies with the purpose of providing access to the space environment for commercial users.

Process computerization of No. 13 blast furnace at Gary works

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sherman, G.J.; Zmierski, M.L.; Hyle, F.W.

1993-10-01

No. 13 blast furnace underwent extensive modifications to the process control system during the second reline. This represents a major shift in control philosophy from hardwired relays and analog controllers to a totally integrated computer control system. The new system created the opportunity for comprehensive diagnostic analysis and increased flexibility for control strategy modifications. The goal of achieving maximum production with minimal delay was accomplished by an integrated test, and comprehensive operator and maintenance training. Normal production was reached within four days of blow-ink and design production capacity of 7800 NTHM/day was met in the third month of operation. Recordmore » furnace productivity of 8931 NTHM/day (8.56 NTHM/100 crwv) was achieved in less than five months of operation and again in April 1992 of 9062 NTHM/day (8.68 NTHM/100 cfwv).« less

The watershed-scale optimized and rearranged landscape design (WORLD) model and local biomass processing depots for sustainable biofuel production: Integrated life cycle assessments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Eranki, Pragnya L.; Manowitz, David H.; Bals, Bryan D.

An array of feedstock is being evaluated as potential raw material for cellulosic biofuel production. Thorough assessments are required in regional landscape settings before these feedstocks can be cultivated and sustainable management practices can be implemented. On the processing side, a potential solution to the logistical challenges of large biorefi neries is provided by a network of distributed processing facilities called local biomass processing depots. A large-scale cellulosic ethanol industry is likely to emerge soon in the United States. We have the opportunity to influence the sustainability of this emerging industry. The watershed-scale optimized and rearranged landscape design (WORLD) modelmore » estimates land allocations for different cellulosic feedstocks at biorefinery scale without displacing current animal nutrition requirements. This model also incorporates a network of the aforementioned depots. An integrated life cycle assessment is then conducted over the unified system of optimized feedstock production, processing, and associated transport operations to evaluate net energy yields (NEYs) and environmental impacts.« less

Integrating Information and Communication Technologies into the Early Childhood Curriculum: Chinese Principals' Views of the Challenges and Opportunities

ERIC Educational Resources Information Center

Li, Hui

2006-01-01

This study investigated the challenges and opportunities associated with the introduction of information and communication technologies (ICT) into the early childhood curriculum in Hong Kong kindergartens. Thirty-one principals completed questionnaires before they implemented a new curriculum initiative plan that involved the integrating of ICT…

Meeting the expectation of industry: an integrated approach for the teaching of mechanics and electronics to design students

NASA Astrophysics Data System (ADS)

Bingham, Guy A.; Southee, Darren J.; Page, Tom

2015-07-01

This paper examines the traditional engineering-based provision delivered to Product Design and Technology (B.Sc.) undergraduates at the Loughborough Design School and questions its relevancy against the increasing expectations of industry. The paper reviews final-year design projects to understand the level of transference of engineering-based knowledge into design practice and highlights areas of opportunity for improved teaching and learning. The paper discusses the development and implementation of an integrated approach to the teaching of Mechanics and Electronics to formalise and reinforce the key learning process of transference within the design context. The paper concludes with observations from the delivery of this integrated teaching and offers insights from student and academic perspectives for the further improvement of engineering-based teaching and learning.

Survey of metallurgical recycling processes. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pemsler, J.P.

1979-03-01

In the year 2000, the US will consume about 3.2 x 10/sup 15/ Btu to produce the seven major nonferrous metals Al, Cu, Zn, Pb, Ni, Mg, and Ti. Of this amount, 82% will be used in the production of Al. It is projected that 0.6 x 10/sup 15/ Btu will be saved by the recycle of secondary metals. Major opportunities for increasing the extent of recycle and thereby increasing the energy savings are discussed. An inherent feature in the energistics of recycle is that physical processes such as magnetic separation, density separations, melting, and in some instances vaporization aremore » far less energy intensive than are chemical processes associated with dissolution and electrowinning. It is in the domain of scrap of complex composition and physical form, difficult to handle by existing technology, that opportunities exist for new chemical recycle technology. Recycle of scrap metal of adequate grade is currently achieved through pyrometallurgical processes which, in many cases, are not very energy intensive as compared with hydrometallurgical processes. Preliminary flowsheets are presented for the recovery of value metals from batteries considered for use in vehicular propulsion and load leveling applications. The battery types examined are lead/acid, nickel/zinc, nickel/iron, zinc/chlorine, lithium-aluminum/iron sulfide, and sodium/sulfur. A flow sheet has been outlined for an integrated hydrometallurgical process to treat low-grade copper scrap. A fully integrated hydrometallurgical process is outlined, and costs and energy consumption are derived, for recovering zinc metal from electric furnace flue dusts. Costs and energy are high and the process does not appear to warrant development at this time. Improvement in the recycle of magnesium is associated primarily with improved recycle in the Al industry where Mg is an important alloy additive. Ni and Ti recycle are associated with improved collection and sorting of stainless steel and specialty alloys.« less

Individual psychotherapy for schizophrenia: trends and developments in the wake of the recovery movement

PubMed Central

Hamm, Jay A; Hasson-Ohayon, Ilanit; Kukla, Marina; Lysaker, Paul H

2013-01-01

Although the role and relative prominence of psychotherapy in the treatment of schizophrenia has fluctuated over time, an analysis of the history of psychotherapy for schizophrenia, focusing on findings from the recovery movement, reveals recent trends including the emergence of the development of integrative psychotherapy approaches. The authors suggest that the recovery movement has revealed limitations in traditional approaches to psychotherapy, and has provided opportunities for integrative approaches to emerge as a mechanism for promoting recovery in persons with schizophrenia. Five approaches to integrative psychotherapy for persons with schizophrenia are presented, and a shared conceptual framework that allows these five approaches to be compatible with one another is proposed. The conceptual framework is consistent with theories of recovery and emphasizes interpersonal attachment, personal narrative, and metacognitive processes. Implications for future research on integrative psychotherapy are considered. PMID:23950665

Enabling Science and Deep Space Exploration through Space Launch System (LSL) Secondary Payload Opportunities

NASA Technical Reports Server (NTRS)

Singer, Jody; Pelfrey, Joseph; Norris, George

2016-01-01

For the first time in almost 40 years, a NASA human-rated launch vehicle has completed its Critical Design Review (CDR). By reaching this milestone, NASA's Space Launch System (SLS) and Orion spacecraft are on the path to launch a new era of deep space exploration. NASA is making investments to expand science and exploration capability of the SLS by developing the capability to deploy small satellites during the trans-lunar phase of the mission trajectory. Exploration Mission 1 (EM-1), currently planned for launch no earlier than July 2018, will be the first mission to carry such payloads on the SLS. The EM-1 launch will include thirteen 6U Cubesat small satellites that will be deployed beyond low earth orbit. By providing an earth-escape trajectory, opportunities are created for advancement of small satellite subsystems, including deep space communications and in-space propulsion. This SLS capability also creates low-cost options for addressing existing Agency strategic knowledge gaps and affordable science missions. A new approach to payload integration and mission assurance is needed to ensure safety of the vehicle, while also maintaining reasonable costs for the small payload developer teams. SLS EM-1 will provide the framework and serve as a test flight, not only for vehicle systems, but also payload accommodations, ground processing, and on-orbit operations. Through developing the requirements and integration processes for EM-1, NASA is outlining the framework for the evolved configuration of secondary payloads on SLS Block upgrades. The lessons learned from the EM-1 mission will be applied to processes and products developed for future block upgrades. In the heavy-lift configuration of SLS, payload accommodations will increase for secondary opportunities including small satellites larger than the traditional Cubesat class payload. The payload mission concept of operations, proposed payload capacity of SLS, and the payload requirements for launch and deployment will be described to provide potential payload users an understanding of this unique exploration capability.

A computer network with scada and case tools for on-line process control in greenhouses

NASA Astrophysics Data System (ADS)

Gieling, Th. H.; van Meurs, W. Th. M.; Janssen, H. J. J.

Climate control computers in greenhouses are used to control heating and ventilation, supply water and dilute and dispense nutrients. They integrate models into optimally controlled systems. This paper describes how information technology, as in use in other sectors of industry, is applied to greenhouse control. The introduction of modern software and hardware concepts in horticulture adds power and extra opportunities to climate control in greenhouses.

Opportunities to Apply the 3Rs in Safety Assessment Programs

PubMed Central

Sewell, Fiona; Edwards, Joanna; Prior, Helen; Robinson, Sally

2016-01-01

Abstract Before a potential new medicine can be administered to humans it is essential that its safety is adequately assessed. Safety assessment in animals forms an integral part of this process, from early drug discovery and initial candidate selection to the program of recommended regulatory tests in animals. The 3Rs (replacement, reduction, and refinement of animals in research) are integrated in the current regulatory requirements and expectations and, in the EU, provide a legal and ethical framework for in vivo research to ensure the scientific objectives are met whilst minimizing animal use and maintaining high animal welfare standards. Though the regulations are designed to uncover potential risks, they are intended to be flexible, so that the most appropriate approach can be taken for an individual product. This article outlines current and future opportunities to apply the 3Rs in safety assessment programs for pharmaceuticals, and the potential (scientific, financial, and ethical) benefits to the industry, across the drug discovery and development process. For example, improvements to, or the development of, novel, early screens (e.g., in vitro, in silico, or nonmammalian screens) designed to identify compounds with undesirable characteristics earlier in development have the potential to reduce late-stage attrition by improving the selection of compounds that require regulatory testing in animals. Opportunities also exist within the current regulatory framework to simultaneously reduce and/or refine animal use and improve scientific outcomes through improvements to technical procedures and/or adjustments to study designs. It is important that approaches to safety assessment are continuously reviewed and challenged to ensure they are science-driven and predictive of relevant effects in humans. PMID:28053076

A Computational Approach to Increase Time Scales in Brownian Dynamics–Based Reaction-Diffusion Modeling

PubMed Central

Frazier, Zachary

2012-01-01

Abstract Particle-based Brownian dynamics simulations offer the opportunity to not only simulate diffusion of particles but also the reactions between them. They therefore provide an opportunity to integrate varied biological data into spatially explicit models of biological processes, such as signal transduction or mitosis. However, particle based reaction-diffusion methods often are hampered by the relatively small time step needed for accurate description of the reaction-diffusion framework. Such small time steps often prevent simulation times that are relevant for biological processes. It is therefore of great importance to develop reaction-diffusion methods that tolerate larger time steps while maintaining relatively high accuracy. Here, we provide an algorithm, which detects potential particle collisions prior to a BD-based particle displacement and at the same time rigorously obeys the detailed balance rule of equilibrium reactions. We can show that for reaction-diffusion processes of particles mimicking proteins, the method can increase the typical BD time step by an order of magnitude while maintaining similar accuracy in the reaction diffusion modelling. PMID:22697237

Optical modulation techniques for analog signal processing and CMOS compatible electro-optic modulation

NASA Astrophysics Data System (ADS)

Gill, Douglas M.; Rasras, Mahmoud; Tu, Kun-Yii; Chen, Young-Kai; White, Alice E.; Patel, Sanjay S.; Carothers, Daniel; Pomerene, Andrew; Kamocsai, Robert; Beattie, James; Kopa, Anthony; Apsel, Alyssa; Beals, Mark; Mitchel, Jurgen; Liu, Jifeng; Kimerling, Lionel C.

2008-02-01

Integrating electronic and photonic functions onto a single silicon-based chip using techniques compatible with mass-production CMOS electronics will enable new design paradigms for existing system architectures and open new opportunities for electro-optic applications with the potential to dramatically change the management, cost, footprint, weight, and power consumption of today's communication systems. While broadband analog system applications represent a smaller volume market than that for digital data transmission, there are significant deployments of analog electro-optic systems for commercial and military applications. Broadband linear modulation is a critical building block in optical analog signal processing and also could have significant applications in digital communication systems. Recently, broadband electro-optic modulators on a silicon platform have been demonstrated based on the plasma dispersion effect. The use of the plasma dispersion effect within a CMOS compatible waveguide creates new challenges and opportunities for analog signal processing since the index and propagation loss change within the waveguide during modulation. We will review the current status of silicon-based electrooptic modulators and also linearization techniques for optical modulation.

A Spatially Based Area–Time Inundation Index Model Developed to Assess Habitat Opportunity in Tidal–Fluvial Wetlands and Restoration Sites

DOE Office of Scientific and Technical Information (OSTI.GOV)

Coleman, Andre M.; Diefenderfer, Heida L.; Ward, Duane L.

The hydrodynamics of tidal wetland areas in the lower Columbia River floodplain and estuary directly affect habitat opportunity for endangered salmonid fishes. Physical and biological structures and functions in the system are directly affected by inundation patterns influenced by tidal cycles, hydropower operations, river discharge, upriver water withdrawals, climate, and physical barriers such as dikes, culverts, and tide gates. Ongoing ecosystem restoration efforts are intended to increase the opportunity for salmon to access beneficial habitats by hydrologically reconnecting main-stem river channels and diked areas within the historical floodplain. To address the need to evaluate habitat opportunity, a geographic information system-basedmore » Area-Time Inundation Index Model (ATIIM) was developed. The ATIIM integrates in situ or modeled hourly water-surface elevation (WSE) data and advanced terrain processing of high-resolution elevation data. The ATIIM uses a spatially based wetted-area algorithm to determine site average bankfull elevation, two- and three-dimensional inundation extent, and other site metrics. Hydrological process metrics such as inundation frequency, duration, maximum area, and maximum frequency area can inform evaluation of proposed restoration sites; e.g., determine trade-offs between WSE and habitat opportunity, contrast alternative restoration designs, predict impacts of altered flow regimes, and estimate nutrient and biomass fluxes. In an adaptive management framework, this model can be used to provide standardized site comparisons and effectiveness monitoring of changes in the developmental trajectories of restoration sites. Results are presented for 11 wetlands representative of tidal marshes, tidal forested wetlands, and restoration sites.« less

Design and Implementation of Collaborative Research Approaches

NASA Technical Reports Server (NTRS)

Venti, Mike W.; Berger, David E.

2009-01-01

This poster reviews the collarborative research approaches that NASA has been designing and implementing for the Integrated Vehicle Health Management (IVHM) Project. The inputs for the technical plan are reviewed, the Research Test and Integration Plan (RTIP) WIKI, is used to create and propose a multi-themed and multi-partner research testing opportunities. The outputs are testing opportunities.

Opportunities and Challenges: Integration of ICT in Teaching and Learning Mathematics in Secondary Schools, Nairobi, Kenya

ERIC Educational Resources Information Center

Amuko, Sheila; Miheso, Marguerite; Ndeuthi, Sophie

2015-01-01

This presentation is based on a larger study whose purpose was to explore the various opportunities and challenges influencing integration of ICT in teaching and learning Mathematics in secondary schools in Nairobi County. The study, adopted a descriptive survey design. Three instruments questionnaires', a structured interview schedule and an…

A Decade of Technology Enhanced Learning at the University of Dar es Salaam, Tanzania: Challenges, Achievements, and Opportunities

ERIC Educational Resources Information Center

Mtebe, Joel S.; Raphael, Christina

2017-01-01

For a decade past, integration of technology in teaching and learning has been received with both apprehension and skeptism from academics and student majority at the University of Dar es Salaam (UDSM). The study recounts real, professional and practical experiences, challenges, and opportunities of integrating educational technologies using…

Proceedings of the 24th Seismic Research Review: Nuclear Explosion Monitoring: Innovation and Integration

DOE Office of Scientific and Technical Information (OSTI.GOV)

Warren, N. Jill

2002-09-17

These proceedings contain papers prepared for the 24th Seismic Research Review: Nuclear Explosion Monitoring: Innovation and Integration, held 17-19 September, 2002 in Ponte Vedra Beach, Florida. These papers represent the combined research related to ground-based nuclear explosion monitoring funded by the National Nuclear Security Administration (NNSA), Defense Threat Reduction Agency (DTRA), and other invited sponsors. The scientific objectives of the research are to improve the United States capability to detect, locate, and identify nuclear explosions. The purpose of the meeting is to provide the sponsoring agencies, as well as potential users, an opportunity to review research accomplished during the precedingmore » year and to discuss areas of investigation for the coming year. For the researchers, it provides a forum for the exchange of scientific information toward achieving program goals, and an opportunity to discuss results and future plans. Paper topics include: seismic regionalization and calibration; detection and location of sources; wave propagation from source to receiver; the nature of seismic sources, including mining practices; hydroacoustic, infrasound, and radionuclide methods; on-site inspection; and data processing.« less

Integration of the subsurface and the surface sectors for a more holistic approach for sustainable redevelopment of urban brownfields.

PubMed

Norrman, Jenny; Volchko, Yevheniya; Hooimeijer, Fransje; Maring, Linda; Kain, Jaan-Henrik; Bardos, Paul; Broekx, Steven; Beames, Alistair; Rosén, Lars

2016-09-01

This paper presents a holistic approach to sustainable urban brownfield redevelopment where specific focus is put on the integration of a multitude of subsurface qualities in the early phases of the urban redevelopment process, i.e. in the initiative and plan phases. Achieving sustainability in brownfield redevelopment projects may be constrained by a failure of engagement between two key expert constituencies: urban planners/designers and subsurface engineers, leading to missed opportunities and unintended outcomes in the plan realisation phase. A more integrated approach delivers greater benefits. Three case studies in the Netherlands, Belgium and Sweden were used to test different sustainability assessment instruments in terms of the possibility for knowledge exchange between the subsurface and the surface sectors and in terms of cooperative learning among experts and stakeholders. Based on the lessons learned from the case studies, a generic decision process framework is suggested that supports holistic decision making. The suggested framework focuses on stakeholder involvement, communication, knowledge exchange and learning and provides an inventory of instruments that can support these processes. Copyright © 2016 Elsevier B.V. All rights reserved.

A strategic value management approach for energy and maintenance management in a building

NASA Astrophysics Data System (ADS)

Nawi, Mohd Nasrun Mohd; Dahlan, Nofri Yenita; Nadarajan, Santhirasegaran

2015-05-01

Fragmentation process is always been highlighted by the stakeholders in the construction industry as one of the `critical' issue that diminishing the opportunity for stakeholders that involved during the operation and maintenance stage to influence design decisions. Failure of design professionals to consider how a maintenance contractor or facility manager will construct the design thus results in higher operating cost, wastage, defects during the maintenance and operation process. Moving towards team integration is considered a significant strategy for overcoming the issue. Value Management is a style of management dedicated to guiding people and promoting innovation with the aim to improve overall building performance through structured, team-oriented exercises which make explicit, and appraise subsequent decisions, by reference to the value requirements of the clients. Accordingly, this paper discusses the fragmentation issue in more detail including the definition, causes and effects to the maintenance and operation of building and at the same time will highlighted the potential of VM integrated team approach as a strategic management approach for overcoming that issue. It also explores that the team integration strategy alleviates scheduling problems, delays and disputes during the construction process, and, hence, prevent harming the overall building performance.

Lean Production as an Innovative Approach to Construction

NASA Astrophysics Data System (ADS)

Spišáková, Marcela; Kozlovská, Mária

2013-06-01

Lean production presents a new approach to the construction management which has enabled enterprises to attain very high levels of efficiency, competitiveness and flexibility in production systems. Nowadays, a number of industrial processes are managed in accordance with these advanced management principles [1]. The principles of lean production are applied within the integrated design and delivery solutions (IDDS) and prefabricated construction. IDDS uses collaborative work processes and enhanced skills, with integrated data, information, and knowledge management to minimize structural and process inefficiencies and to enhance the value delivered during design, build, and operation, and across projects. Prefabrication presents a one of opportunities for construction methods, which allows the compliance with principles of sustainable design, provides the potential benefits such as faster construction, fewer housing defects, reduction in energy use and waste and elimination of environmental and safety risks. This paper presents the lean production within the IDDS and its potential in the modern prefabrication. There is created a field providing of benefits of lean production in construction industry.

Interfaces and Integration of Medical Image Analysis Frameworks: Challenges and Opportunities.

PubMed

Covington, Kelsie; McCreedy, Evan S; Chen, Min; Carass, Aaron; Aucoin, Nicole; Landman, Bennett A

2010-05-25

Clinical research with medical imaging typically involves large-scale data analysis with interdependent software toolsets tied together in a processing workflow. Numerous, complementary platforms are available, but these are not readily compatible in terms of workflows or data formats. Both image scientists and clinical investigators could benefit from using the framework which is a most natural fit to the specific problem at hand, but pragmatic choices often dictate that a compromise platform is used for collaboration. Manual merging of platforms through carefully tuned scripts has been effective, but exceptionally time consuming and is not feasible for large-scale integration efforts. Hence, the benefits of innovation are constrained by platform dependence. Removing this constraint via integration of algorithms from one framework into another is the focus of this work. We propose and demonstrate a light-weight interface system to expose parameters across platforms and provide seamless integration. In this initial effort, we focus on four platforms Medical Image Analysis and Visualization (MIPAV), Java Image Science Toolkit (JIST), command line tools, and 3D Slicer. We explore three case studies: (1) providing a system for MIPAV to expose internal algorithms and utilize these algorithms within JIST, (2) exposing JIST modules through self-documenting command line interface for inclusion in scripting environments, and (3) detecting and using JIST modules in 3D Slicer. We review the challenges and opportunities for light-weight software integration both within development language (e.g., Java in MIPAV and JIST) and across languages (e.g., C/C++ in 3D Slicer and shell in command line tools).

Printed Carbon Nanotube Electronics and Sensor Systems.

PubMed

Chen, Kevin; Gao, Wei; Emaminejad, Sam; Kiriya, Daisuke; Ota, Hiroki; Nyein, Hnin Yin Yin; Takei, Kuniharu; Javey, Ali

2016-06-01

Printing technologies offer large-area, high-throughput production capabilities for electronics and sensors on mechanically flexible substrates that can conformally cover different surfaces. These capabilities enable a wide range of new applications such as low-cost disposable electronics for health monitoring and wearables, extremely large format electronic displays, interactive wallpapers, and sensing arrays. Solution-processed carbon nanotubes have been shown to be a promising candidate for such printing processes, offering stable devices with high performance. Here, recent progress made in printed carbon nanotube electronics is discussed in terms of materials, processing, devices, and applications. Research challenges and opportunities moving forward from processing and system-level integration points of view are also discussed for enabling practical applications. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Biracial Japanese American identity: an evolving process.

PubMed

Collins, J F

2000-05-01

This qualitative study explored the complexity of biracial identity development in Japanese Americans. It is based on the constant comparable method of analysis, or grounded theory. The study focused on how Japanese Americans perceived themselves in relation to other individuals, groups, and their environment. The data consisted of 15 extensive semistructured interviews with 8 men and 7 women (ages 20 to 40 years), each with 1 Japanese parent and 1 non-Asian parent. Findings relate to participants' initiating explorations of identity and perseverance in pursuing a biracial identity, which depended on the degree of support or negative experience within their social networks. Participants explored identity options attempting to develop their own meaning of identity, to develop a confident sense of themselves, and to secure a positive ethnic identity. Identity development among participants varied. It was a long-term process involving changes in the individual-environment relationship, which differed in the way individual participants influenced or selected from environmental opportunities, even creating or recreating some aspects. Within a given setting, as youths, the potential for social experiences were relatively fixed and changed only gradually. As adults, there were opportunities for participants to select their own social and geographic settings, providing opportunity for change. In their new environments, participants were exposed to new contacts and role models, acquired new behavioral repertoire, and underwent role transitions. Depending on this, new and different aspects of biracial identity developed. Participants indicated it was an emotional and conflictual process to positive assertion of identity. Before reaching this, all of the participants experienced periods of confusion. Most asserted biracial identity gradually, through a process of racial identity development consisting of the individual's changing or maintaining certain reference group perspectives, identifications, and allegiances as they passed through a series of life experiences. Instead of staying marginalized, they integrated both cultures, recognizing positive values of both, thus developing an integrated identity. Although the participants' experiences and perceptions were varied, the overarching themes of self-evaluation, confusion of categorization, belonging, infusion/exploration, situational use of identity, and resolution/acceptance/self-verification were presented. On the basis of the research, a model of ethnic identity for biracial individuals is proposed.

Product manufacturing, quality, and reliability initiatives to maintain a competitive advantage and meet customer expectations in the semiconductor industry

NASA Astrophysics Data System (ADS)

Capps, Gregory

Semiconductor products are manufactured and consumed across the world. The semiconductor industry is constantly striving to manufacture products with greater performance, improved efficiency, less energy consumption, smaller feature sizes, thinner gate oxides, and faster speeds. Customers have pushed towards zero defects and require a more reliable, higher quality product than ever before. Manufacturers are required to improve yields, reduce operating costs, and increase revenue to maintain a competitive advantage. Opportunities exist for integrated circuit (IC) customers and manufacturers to work together and independently to reduce costs, eliminate waste, reduce defects, reduce warranty returns, and improve quality. This project focuses on electrical over-stress (EOS) and re-test okay (RTOK), two top failure return mechanisms, which both make great defect reduction opportunities in customer-manufacturer relationship. Proactive continuous improvement initiatives and methodologies are addressed with emphasis on product life cycle, manufacturing processes, test, statistical process control (SPC), industry best practices, customer education, and customer-manufacturer interaction.

Producing picture-perfect posters.

PubMed

Bach, D B; Vellet, A D; Karlik, S J; Downey, D B; Levin, M F; Munk, P L

1993-06-01

Scientific posters form an integral part of many radiology meetings. They provide the opportunity for interested parties to read the material at an individualized pace, to study the images in detail, and to return to the exhibit numerous times. Although the content of the poster is undoubtedly its most important component, the visual presentation of the material can enhance or detract from the clarity of the message. With the wide availability of sophisticated computer programs for desktop publishing (DTP), one can now create the poster on a computer monitor with full control of the form as well as the content. This process will result in a professional-appearing poster, yet still allow the author the opportunity to make innumerable revisions, as the poster is visualized in detail on the computer monitor before printing. Furthermore, this process is less expensive than the traditional method of typesetting individual sections separately and mounting them on cardboard for display. The purpose of this article is to present our approach to poster production using commercially available DTP computer programs.

BIO-Plex Information System Concept

NASA Technical Reports Server (NTRS)

Jones, Harry; Boulanger, Richard; Arnold, James O. (Technical Monitor)

1999-01-01

This paper describes a suggested design for an integrated information system for the proposed BIO-Plex (Bioregenerative Planetary Life Support Systems Test Complex) at Johnson Space Center (JSC), including distributed control systems, central control, networks, database servers, personal computers and workstations, applications software, and external communications. The system will have an open commercial computing and networking, architecture. The network will provide automatic real-time transfer of information to database server computers which perform data collection and validation. This information system will support integrated, data sharing applications for everything, from system alarms to management summaries. Most existing complex process control systems have information gaps between the different real time subsystems, between these subsystems and central controller, between the central controller and system level planning and analysis application software, and between the system level applications and management overview reporting. An integrated information system is vitally necessary as the basis for the integration of planning, scheduling, modeling, monitoring, and control, which will allow improved monitoring and control based on timely, accurate and complete data. Data describing the system configuration and the real time processes can be collected, checked and reconciled, analyzed and stored in database servers that can be accessed by all applications. The required technology is available. The only opportunity to design a distributed, nonredundant, integrated system is before it is built. Retrofit is extremely difficult and costly.

Resource recovery from landfill leachate using bioelectrochemical systems: Opportunities, challenges, and perspectives.

PubMed

Iskander, Syeed Md; Brazil, Brian; Novak, John T; He, Zhen

2016-02-01

Landfill leachate has recently been investigated as a substrate for bioelectrochemical systems (BES) for electricity generation. While BES treatment of leachate is effective, the unique feature of bioelectricity generation in BES creates opportunities for resource recovery from leachate. The organic compounds in leachate can be directly converted to electrical energy through microbial interaction with solid electron acceptors/donors. Nutrient such as ammonia can be recovered via ammonium migration driven by electricity generation and ammonium conversion to ammonia in a high-pH condition that is a result of cathode reduction reaction. Metals in leachate may also be recovered, but the recovery is affected by their concentrations and values. Through integrating membrane process, especially forward osmosis, BES can recover high-quality water from leachate for applications in landscaping, agricultural irrigation or direct discharge. This review paper discusses the opportunities, challenges, and perspectives of resource recovery from landfill leachate by using BES. Copyright © 2015 Elsevier Ltd. All rights reserved.

Medical Group Structural Integration May Not Ensure That Care Is Integrated, From The Patient's Perspective.

PubMed

Kerrissey, Michaela J; Clark, Jonathan R; Friedberg, Mark W; Jiang, Wei; Fryer, Ashley K; Frean, Molly; Shortell, Stephen M; Ramsay, Patricia P; Casalino, Lawrence P; Singer, Sara J

2017-05-01

Structural integration is increasing among medical groups, but whether these changes yield care that is more integrated remains unclear. We explored the relationships between structural integration characteristics of 144 medical groups and perceptions of integrated care among their patients. Patients' perceptions were measured by a validated national survey of 3,067 Medicare beneficiaries with multiple chronic conditions across six domains that reflect knowledge and support of, and communication with, the patient. Medical groups' structural characteristics were taken from the National Study of Physician Organizations and included practice size, specialty mix, technological capabilities, and care management processes. Patients' survey responses were most favorable for the domain of test result communication and least favorable for the domain of provider support for medication and home health management. Medical groups' characteristics were not consistently associated with patients' perceptions of integrated care. However, compared to patients of primary care groups, patients of multispecialty groups had strong favorable perceptions of medical group staff knowledge of patients' medical histories. Opportunities exist to improve patient care, but structural integration of medical groups might not be sufficient for delivering care that patients perceive as integrated. Project HOPE—The People-to-People Health Foundation, Inc.

Electrically Isolating Subsystems in SOAC Technologies

NASA Technical Reports Server (NTRS)

Boyd, R. M.; Mojarradi, M. M.; Kuhn, W. B.; Shumaker, E. A.

2001-01-01

Integrated circuit fabrication technology has evolved to the point that it is possible to construct complete systems, including power, data processing, and communications, on a single chip. Such System-on-a-chip (SOAC) technologies can enable drastic reductions in spacecraft size and weight, lowering the cost of missions and presenting new mission opportunities. This paper overviews some key enabling technologies unique to the needs of spacecraft for outer-planet exploration and missions requiring extreme resistance to radiation such as Europa orbiters and Europa Landers. The work is being carried out by Kansas State University (KSU) under direction of the Center for Integrated Space Microsystems (CISM) at NASA's Jet Propulsion Laboratory. Additional information is contained in the original extended abstract.

High Fidelity Additive Manufacturing of Optically Transparent Glass Structures

NASA Astrophysics Data System (ADS)

Inamura, Chikara

Glass has been an integral part of human civilization with expressions across scales and disciplines: from the microscope to the telescope, from fiber optics to mobile interface, and from the petri dish to a building envelope. Such a diverse range of applications is enabled by the inherent material properties including mechanical strength, optical transparency and chemical inertness. Additive manufacturing provides opportunities for integrating the unique properties of glass to engineer novel structures that are functionary graded through precise spatiotemporal deposition of molten glass. This talk presents the Mediated Matter Group's latest development of a novel additive manufacturing platform, and related processes, for 3D Printing optically transparent glass for architectural scale applications.

Thin film transistors for flexible electronics: contacts, dielectrics and semiconductors.

PubMed

Quevedo-Lopez, M A; Wondmagegn, W T; Alshareef, H N; Ramirez-Bon, R; Gnade, B E

2011-06-01

The development of low temperature, thin film transistor processes that have enabled flexible displays also present opportunities for flexible electronics and flexible integrated systems. Of particular interest are possible applications in flexible sensor systems for unattended ground sensors, smart medical bandages, electronic ID tags for geo-location, conformal antennas, radiation detectors, etc. In this paper, we review the impact of gate dielectrics, contacts and semiconductor materials on thin film transistors for flexible electronics applications. We present our recent results to fully integrate hybrid complementary metal oxide semiconductors comprising inorganic and organic-based materials. In particular, we demonstrate novel gate dielectric stacks and semiconducting materials. The impact of source and drain contacts on device performance is also discussed.

A model biorefinery for avocado (Persea americana mill.) processing.

PubMed

Dávila, Javier A; Rosenberg, Moshe; Castro, Eulogio; Cardona, Carlos A

2017-11-01

This research investigated and evaluated a biorefinery for processing avocado Hass variety into microencapsulated phenolic compounds extract, ethanol, oil and xylitol. Avocado was first characterized for its potential valuable compounds; then, the techno-economic and environmental aspects of the biorefinery were developed and finally the total production costs and potential environmental impact of the proposed biorefinery were investigated. Four scenarios of the biorefinery were evaluated with different extent of mass and energy integration as well as the incorporation of a cogeneration system. Results indicated that the main fatty acid in the pulp of the investigated avocado variety was oleic acid (50.96%) and that this fruit contained significant amount of holocellulose (52.88% and 54.36% in the peel and seed, respectively). Techno-economic and environmental assessment suggested an attractive opportunity for a biorefinery for complete utilization of the avocado fruit as well the importance of the level of integration. Copyright © 2017 Elsevier Ltd. All rights reserved.

Smart electronics and microengineering: the Australian focus

NASA Astrophysics Data System (ADS)

Hariz, Alex

1998-04-01

Integrated MEMS together with signal-conditioning electronics on the same chip appears to be the ultimate solution to realizing smart computer devices integratable into larger systems. This in principle will lead to systems with decentralized intelligence leading to applications in numerous fields. It is conceived that such devices would be the product of merging two mature technologies, that of microsensors and that of IC manufacture which is enjoying a well established success. Using common and suitable materials it is reasonable to expect a high degree of compatibility with little modification to standard processes. The various aspects of this co-integration will be analyzed and factors critical to the viability of the process, that go beyond mere technical feasibility will be highlighted. Australian research in this area is strong and continues to grow. We will pinpoint opportunities and constraints to the promising prospect of smart electronics and MEMS.

Patient Web Portals to Improve Diabetes Outcomes: A Systematic Review

PubMed Central

Mayberry, Lindsay Satterwhite; Mulvaney, Shelagh A.; Hess, Rachel

2011-01-01

Patient web portals (PWPs), defined as the integration of electronic medical records and patient health records, have been related to enhanced patient outcomes. A literature review was conducted to characterize the design and evaluation of PWPs to improve health care processes and outcomes in diabetes. A summary of 26 articles revealed the positive impact PWPs have on patient outcomes, patient-provider communication, disease management, and access to and patient satisfaction with health care. Innovative and useful approaches included the evaluation of specific components of the PWPs, assessing the impact of PWPs on mediators of health behaviors, such as patient distress, identification of barriers to use, and patient willingness to pay for access. Future research should focus on relevant processes that mediate patient and provider use, impact on health care utilization, and a patient-centered approach to the design and integration of educational opportunities afforded through PWPs. PMID:20890688

Patient web portals to improve diabetes outcomes: a systematic review.

PubMed

Osborn, Chandra Y; Mayberry, Lindsay Satterwhite; Mulvaney, Shelagh A; Hess, Rachel

2010-12-01

Patient web portals (PWPs), defined as the integration of electronic medical records and patient health records, have been related to enhanced patient outcomes. A literature review was conducted to characterize the design and evaluation of PWPs to improve health care processes and outcomes in diabetes. A summary of 26 articles revealed the positive impact PWPs have on patient outcomes, patient-provider communication, disease management, and access to and patient satisfaction with health care. Innovative and useful approaches included the evaluation of specific components of the PWPs, assessing the impact of PWPs on mediators of health behaviors, such as patient distress, identification of barriers to use, and patient willingness to pay for access. Future research should focus on relevant processes that mediate patient and provider use, impact on health care utilization, and a patient-centered approach to the design and integration of educational opportunities afforded through PWPs.

Enhancing multiple disciplinary teamwork.

PubMed

Weaver, Terri E

2008-01-01

Multiple disciplinary research provides an opportunity to bring together investigators across disciplines to provide new views and develop innovative approaches to important questions. Through this shared experience, novel paradigms are formed, original frameworks are developed, and new language is generated. Integral to the successful construction of effective cross-disciplinary teams is the recognition of antecedent factors that affect the development of the team such as intrapersonal, social, physical environmental, organizational, and institutional influences. Team functioning is enhanced with well-developed behavioral, affective, interpersonal, and intellectual processes. Outcomes of effective multiple disciplinary research teams include novel ideas, integrative models, new training programs, institutional change, and innovative policies that can also influence the degree to which antecedents and processes contribute to team performance. Ongoing evaluation of team functioning and achievement of designated outcomes ensures the continued development of the multiple disciplinary team and confirmation of this approach as important to the advancement of science.

The Home Stretch Almost! Science with the Hubble and James Webb Space Telescope V

NASA Technical Reports Server (NTRS)

Ochs, Bill

2017-01-01

JWST has Made tremendous progress in the last few years. JWST Is fully immersed in integration and test, but testing JWST is a formable challenge. JWST's size, complexity, and cryogenic characteristics require a multifaceted test plan to verify mission readiness. Each of these tests are opportunities to uncover issues which must be corrected to be able to move forward. All observatory control, science planning, and science data processing operational systems are on schedule.?

Sensory processing in autism spectrum disorders and Fragile X syndrome—From the clinic to animal models

PubMed Central

Sinclair, D.; Oranje, B.; Razak, K.A.; Siegel, S.J.; Schmid, S.

2017-01-01

Brains are constantly flooded with sensory information that needs to be filtered at the pre-attentional level and integrated into endogenous activity in order to allow for detection of salient information and an appropriate behavioral response. People with Autism Spectrum Disorder (ASD) or Fragile X Syndrome (FXS) are often over- or under-reactive to stimulation, leading to a wide range of behavioral symptoms. This altered sensitivity may be caused by disrupted sensory processing, signal integration and/or gating, and is often being neglected. Here, we review translational experimental approaches that are used to investigate sensory processing in humans with ASD and FXS, and in relevant rodent models. This includes electroencephalographic measurement of event related potentials, neural oscillations and mismatch negativity, as well as habituation and pre-pulse inhibition of startle. We outline robust evidence of disrupted sensory processing in individuals with ASD and FXS, and in respective animal models, focusing on the auditory sensory domain. Animal models provide an excellent opportunity to examine common mechanisms of sensory pathophysiology in order to develop therapeutics. PMID:27235081

Performance Measurement using KPKU- BUMN in X School Education Foundation

NASA Astrophysics Data System (ADS)

Arijanto, Sugih; Harsono, Ambar; Taroepratjeka, Harsono

2016-01-01

The purpose of this research is to determine X School's Strengths and Opportunity of Improvement through performance measurement using KPKU-BUMN (Kriteria Penilaian Kinerja Unggul - Kementerian Badan Usaha Milik Negara). KPKU-BUMN is developed based on Malcolm Baldrige Criteria for Performance Excellent (MBCfPE). X school is an education foundation at Bandung that has provides education from kindergarten, elementary school, to junior and senior high school. The measurement is implemented by two aspects, Process and Result. The Process is measured by A-D-L-I approaches (Approach- Deployment-Learning- Integration), on the other hand The Result is measured by Le-T-C-I approach (Level-Trend- Comparison-Integration). There are six processes that will be measured: (1) Leadership, (2) Strategic Planning, (3) Customer Focus, (4) Measurement, Analysis and Knowledge Management, (5) Work Force Focus, and (6) Operation Focus. Meanwhile, the result are (a) product & process outcomes, (b) customer-focused outcomes, (c) workforce-focused outcomes, (d) leadership & governance outcomes, and (e) financial & market outcomes. The overall score for X School is 284/1000, which means X School is at “early result” level at “poor” global image.

Looking beyond borders: integrating best practices in benefit-risk analysis into the field of food and nutrition.

PubMed

Tijhuis, M J; Pohjola, M V; Gunnlaugsdóttir, H; Kalogeras, N; Leino, O; Luteijn, J M; Magnússon, S H; Odekerken-Schröder, G; Poto, M; Tuomisto, J T; Ueland, O; White, B C; Holm, F; Verhagen, H

2012-01-01

An integrated benefit-risk analysis aims to give guidance in decision situations where benefits do not clearly prevail over risks, and explicit weighing of benefits and risks is thus indicated. The BEPRARIBEAN project aims to advance benefit-risk analysis in the area of food and nutrition by learning from other fields. This paper constitutes the final stage of the project, in which commonalities and differences in benefit-risk analysis are identified between the Food and Nutrition field and other fields, namely Medicines, Food Microbiology, Environmental Health, Economics and Marketing-Finance, and Consumer Perception. From this, ways forward are characterized for benefit-risk analysis in Food and Nutrition. Integrated benefit-risk analysis in Food and Nutrition may advance in the following ways: Increased engagement and communication between assessors, managers, and stakeholders; more pragmatic problem-oriented framing of assessment; accepting some risk; pre- and post-market analysis; explicit communication of the assessment purpose, input and output; more human (dose-response) data and more efficient use of human data; segmenting populations based on physiology; explicit consideration of value judgments in assessment; integration of multiple benefits and risks from multiple domains; explicit recognition of the impact of consumer beliefs, opinions, views, perceptions, and attitudes on behaviour; and segmenting populations based on behaviour; the opportunities proposed here do not provide ultimate solutions; rather, they define a collection of issues to be taken account of in developing methods, tools, practices and policies, as well as refining the regulatory context, for benefit-risk analysis in Food and Nutrition and other fields. Thus, these opportunities will now need to be explored further and incorporated into benefit-risk practice and policy. If accepted, incorporation of these opportunities will also involve a paradigm shift in Food and Nutrition benefit-risk analysis towards conceiving the analysis as a process of creating shared knowledge among all stakeholders. Copyright © 2011 Elsevier Ltd. All rights reserved.

Reducing Physical Risk Factors in Construction Work Through a Participatory Intervention: Protocol for a Mixed-Methods Process Evaluation.

PubMed

Ajslev, Jeppe; Brandt, Mikkel; Møller, Jeppe Lykke; Skals, Sebastian; Vinstrup, Jonas; Jakobsen, Markus Due; Sundstrup, Emil; Madeleine, Pascal; Andersen, Lars Louis

2016-05-26

Previous research has shown that reducing physical workload among workers in the construction industry is complicated. In order to address this issue, we developed a process evaluation in a formative mixed-methods design, drawing on existing knowledge of the potential barriers for implementation. We present the design of a mixed-methods process evaluation of the organizational, social, and subjective practices that play roles in the intervention study, integrating technical measurements to detect excessive physical exertion measured with electromyography and accelerometers, video documentation of working tasks, and a 3-phased workshop program. The evaluation is designed in an adapted process evaluation framework, addressing recruitment, reach, fidelity, satisfaction, intervention delivery, intervention received, and context of the intervention companies. Observational studies, interviews, and questionnaires among 80 construction workers organized in 20 work gangs, as well as health and safety staff, contribute to the creation of knowledge about these phenomena. At the time of publication, the process of participant recruitment is underway. Intervention studies are challenging to conduct and evaluate in the construction industry, often because of narrow time frames and ever-changing contexts. The mixed-methods design presents opportunities for obtaining detailed knowledge of the practices intra-acting with the intervention, while offering the opportunity to customize parts of the intervention.

Genomic Medicine and Lung Diseases

PubMed Central

Center, David M.; Schwartz, David A.; Solway, Julian; Gail, Dorothy; Laposky, Aaron D.

2012-01-01

The recent explosion of genomic data and technology points to opportunities to redefine lung diseases at the molecular level; to apply integrated genomic approaches to elucidate mechanisms of lung pathophysiology; and to improve early detection, diagnosis, and treatment of lung diseases. Research is needed to translate genomic discoveries into clinical applications, such as detecting preclinical disease, predicting patient outcomes, guiding treatment choices, and most of all identifying potential therapeutic targets for lung diseases. The Division of Lung Diseases in the National Heart, Lung, and Blood Institute convened a workshop, “Genomic Medicine and Lung Diseases,” to discuss the potential for integrated genomics and systems approaches to advance 21st century pulmonary medicine and to evaluate the most promising opportunities for this next phase of genomics research to yield clinical benefit. Workshop sessions included (1) molecular phenotypes, molecular biomarkers, and therapeutics; (2) new technology and opportunity; (3) integrative genomics; (4) molecular anatomy of the lung; (5) novel data and information platforms; and (6) recommendations for exceptional research opportunities in lung genomics research. PMID:22652029

Do IDSs really benefit from affiliating with managed care plans?

PubMed

Hogan, K; Thomopoulos, M

1998-02-01

Integrated delivery systems (IDSs) affiliate with HMOs primarily to gain access to patients enrolled in managed care plans. Outright ownership of an HMO offers an IDS additional advantages, including opportunities to create a more seamless care process, improve patient outcomes, draw on the HMOs' experience in reducing costs, and administer health management and delivery at a significantly lower cost than the industry standard. The current trend toward IDS ownership of HMOs suggests that the line between providers and payers is blurring. Some states have encouraged this trend by enacting legislation that allows IDSs to act as insurers. Recent data indicate that IDSs with HMO components tend to be more vertically integrated than those without such components. These data suggest that close alignment with an HMO may be a key element in the effort to achieve vertical integration.

Fiber Bragg grating sensor interrogators on chip: challenges and opportunities

NASA Astrophysics Data System (ADS)

Marin, Yisbel; Nannipieri, Tiziano; Oton, Claudio J.; Di Pasquale, Fabrizio

2017-04-01

In this paper we present an overview of the current efforts towards integration of Fiber Bragg Grating (FBG) sensor interrogators. Different photonic integration platforms will be discussed, including monolithic planar lightwave circuit technology, silicon on insulator (SOI), indium phosphide (InP) and gallium arsenide (GaAs) material platforms. Also various possible techniques for wavelength metering and methods for FBG multiplexing will be discussed and compared in terms of resolution, dynamic performance, multiplexing capabilities and reliability. The use of linear filters, array waveguide gratings (AWG) as multiple linear filters and AWG based centroid signal processing techniques will be addressed as well as interrogation techniques based on tunable micro-ring resonators and Mach-Zehnder interferometers (MZI) for phase sensitive detection. The paper will also discuss the challenges and perspectives of photonic integration to address the increasing requirements of several industrial applications.

A Review of Surgical Informed Consent: Past, Present, and Future. A Quest to Help Patients Make Better Decisions

PubMed Central

Keulers, Bram J.; Scheltinga, Marc R. M.; Spauwen, Paul H. M.; van der Wilt, Gert-Jan

2010-01-01

Background Informed consent (IC) is a process requiring a competent doctor, adequate transfer of information, and consent of the patient. It is not just a signature on a piece of paper. Current consent processes in surgery are probably outdated and may require major changes to adjust them to modern day legislation. A literature search may provide an opportunity for enhancing the quality of the surgical IC (SIC) process. Methods Relevant English literature obtained from PubMed, Picarta, PsycINFO, and Google between 1993 and 2009 was reviewed. Results The body of literature with respect to SIC is slim and of moderate quality. The SIC process is an underestimated part of surgery and neither surgeons nor patients sufficiently realize its importance. Surgeons are not specifically trained and lack the competence to guide patients through a legally correct SIC process. Computerized programs can support the SIC process significantly but are rarely used for this purpose. Conclusions IC should be integrated into our surgical practice. Unfortunately, a big gap exists between the theoretical/legal best practice and the daily practice of IC. An optimally informed patient will have more realistic expectations regarding a surgical procedure and its associated risks. Well-informed patients will be more satisfied and file fewer legal claims. The use of interactive computer-based programs provides opportunities to improve the SIC process. PMID:20372902

A CMOS microdisplay with integrated controller utilizing improved silicon hot carrier luminescent light sources

NASA Astrophysics Data System (ADS)

Venter, Petrus J.; Alberts, Antonie C.; du Plessis, Monuko; Joubert, Trudi-Heleen; Goosen, Marius E.; Janse van Rensburg, Christo; Rademeyer, Pieter; Fauré, Nicolaas M.

2013-03-01

Microdisplay technology, the miniaturization and integration of small displays for various applications, is predominantly based on OLED and LCoS technologies. Silicon light emission from hot carrier electroluminescence has been shown to emit light visibly perceptible without the aid of any additional intensification, although the electrical to optical conversion efficiency is not as high as the technologies mentioned above. For some applications, this drawback may be traded off against the major cost advantage and superior integration opportunities offered by CMOS microdisplays using integrated silicon light sources. This work introduces an improved version of our previously published microdisplay by making use of new efficiency enhanced CMOS light emitting structures and an increased display resolution. Silicon hot carrier luminescence is often created when reverse biased pn-junctions enter the breakdown regime where impact ionization results in carrier transport across the junction. Avalanche breakdown is typically unwanted in modern CMOS processes. Design rules and process design are generally tailored to prevent breakdown, while the voltages associated with breakdown are too high to directly interact with the rest of the CMOS standard library. This work shows that it is possible to lower the operating voltage of CMOS light sources without compromising the optical output power. This results in more efficient light sources with improved interaction with other standard library components. This work proves that it is possible to create a reasonably high resolution microdisplay while integrating the active matrix controller and drivers on the same integrated circuit die without additional modifications, in a standard CMOS process.

Integrated approach for improving small scale market oriented dairy systems in Pakistan: participatory rural appraisal and economic opportunity survey.

PubMed

Ghaffar, Abdul; Khan, M Qasim; Ullah, Nemat

2007-12-01

Livestock production is an integral part of the rain-fed and irrigated agriculture system in Pakistan. Animal production is closely interlinked with the cropping systems and play a crucial role in the rural economy. Participatory rural appraisals and economic opportunity surveys were conducted in two ecological zones (irrigated and rain-fed) and two dairy production systems (peri-urban and mixed livestock). Major constraints in animal health, nutrition and reproduction were identified and interventions were suggested to overcome these difficulties. The economic opportunity survey revealed that maximum opportunity to enhance farmers' income is to increase milk production per day per animal, which can be accomplished through coordinated improvements in nutrition, reproduction and genetics.

The 2005 Thomas Willis Lecture: stroke and vascular cognitive impairment: a transdisciplinary, translational and transactional approach.

PubMed

Hachinski, Vladimir

2007-04-01

Advances in stroke are occurring at an unprecedented pace, but often in disciplinary isolation and without optimal mechanisms for systematically translating, integrating and applying the findings. Knowledge accrues in pieces, but is understood in patterns. To optimize knowledge acquisition and application, infrastructures and systems need to be set up along with appealing incentives. The approach needs to be transdisciplinary, going beyond the bounds of any given discipline, reciprocally translational, and transactional, meaning that the interchanges have to yield previously agreed benefits to the parties (The Triple T Approach). A new breed of leaders needs to be developed and nurtured to catalyze the process. Opportunities abound. Stroke and most brain diseases share the same pathophysiological fundamental mechanisms. An integrated, systematic approach to these processes could yield not only greater understanding but new, common therapeutic targets for several diseases. Biphasic clinical trials could combine the best features of pragmatic and explanatory, randomized clinical trials. The greatest opportunity of all may be the largely under-explored and under-exploited borderlands between cerebrovascular and Alzheimer disease. One in three of us will have a stroke, become demented, or both. For each person who has a stroke or Alzheimer disease, two have some cognitive impairment short of dementia, often subclinical cerebrovascular disease on a substrate of Alzheimer changes. The fact that cerebrovascular and Alzheimer disease share the same risk factors, provide a great opportunity for prevention, if implemented at the "brain at risk" stage. Systematically integrating what we know and evaluating what we do could spur progress. Research is not only an activity but an attitude. Making evaluation and incentives to excel part of the funding of all stroke activities would yield far ranging cumulative improvements in all aspects of stroke. No system can replace the individual initiative, creativity and insights that lead to the great discoveries, but progress is not made by breakthroughs alone. No one's work is so exalted that it cannot be improved, nor so humble that it has no value. We can all make a difference.

VHDL Implementation of Sigma-Delta Analog To Digital Converter

NASA Astrophysics Data System (ADS)

Chavan, R. N.; Chougule, D. G.

2010-11-01

Sigma-Delta modulation techniques provide a range of opportunities in a signal processing system for both increasing performance and data path optimization along the silicon area axis in the design space. One of the most challenging tasks in Analog to Digital Converter (ADC) design is to adapt the circuitry to ever new CMOS process technology. For digital circuits the number of gates per square mm app. doubles per chip generation. Integration of analog parts in newer deep submicron technologies is much more tough and additionally complicated because the usable voltage ranges are decreasing with every new integration step. This paper shows an approach which only uses 2 resistors and 1 capacitor which are located outside a pure digital chip. So all integration advantages of pure digital chips are preserved, there is no design effort for a new chip generation and the ADC also can be used for FPGAs. Resolutions of up to 16 bit are achievable. Sample rates in the 1 MHz region are feasible so that the approach is also useful for ADCs for xDSL technologies.

Radiomics in radiooncology - Challenging the medical physicist.

PubMed

Peeken, Jan C; Bernhofer, Michael; Wiestler, Benedikt; Goldberg, Tatyana; Cremers, Daniel; Rost, Burkhard; Wilkens, Jan J; Combs, Stephanie E; Nüsslin, Fridtjof

2018-04-01

Noticing the fast growing translation of artificial intelligence (AI) technologies to medical image analysis this paper emphasizes the future role of the medical physicist in this evolving field. Specific challenges are addressed when implementing big data concepts with high-throughput image data processing like radiomics and machine learning in a radiooncology environment to support clinical decisions. Based on the experience of our interdisciplinary radiomics working group, techniques for processing minable data, extracting radiomics features and associating this information with clinical, physical and biological data for the development of prediction models are described. A special emphasis was placed on the potential clinical significance of such an approach. Clinical studies demonstrate the role of radiomics analysis as an additional independent source of information with the potential to influence the radiooncology practice, i.e. to predict patient prognosis, treatment response and underlying genetic changes. Extending the radiomics approach to integrate imaging, clinical, genetic and dosimetric data ('panomics') challenges the medical physicist as member of the radiooncology team. The new field of big data processing in radiooncology offers opportunities to support clinical decisions, to improve predicting treatment outcome and to stimulate fundamental research on radiation response both of tumor and normal tissue. The integration of physical data (e.g. treatment planning, dosimetric, image guidance data) demands an involvement of the medical physicist in the radiomics approach of radiooncology. To cope with this challenge national and international organizations for medical physics should organize more training opportunities in artificial intelligence technologies in radiooncology. Copyright © 2018 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

Towards a Better Understanding of CMMI and Agile Integration - Multiple Case Study of Four Companies

NASA Astrophysics Data System (ADS)

Pikkarainen, Minna

The amount of software is increasing in the different domains in Europe. This provides the industries in smaller countries good opportunities to work in the international markets. Success in the global markets however demands the rapid production of high quality, error free software. Both CMMI and agile methods seem to provide a ready solution for quality and lead time improvements. There is not, however, much empirical evidence available either about 1) how the integration of these two aspects can be done in practice or 2) what it actually demands from assessors and software process improvement groups. The goal of this paper is to increase the understanding of CMMI and agile integration, in particular, focusing on the research question: how to use ‘lightweight’ style of CMMI assessments in agile contexts. This is done via four case studies in which assessments were conducted using the goals of CMMI integrated project management and collaboration and coordination with relevant stakeholder process areas and practices from XP and Scrum. The study shows that the use of agile practices may support the fulfilment of the goals of CMMI process areas but there are still many challenges for the agile teams to be solved within the continuous improvement programs. It also identifies practical advices to the assessors and improvement groups to take into consideration when conducting assessment in the context of agile software development.

Tropical forest response to elevated CO2: Model-experiment integration at the AmazonFACE site.

NASA Astrophysics Data System (ADS)

Frankenberg, C.; Berry, J. A.; Guanter, L.; Joiner, J.

2014-12-01

The terrestrial biosphere's response to current and future elevated atmospheric carbon dioxide (eCO2) is a large source of uncertainty in future projections of the C cycle, climate and ecosystem functioning. In particular, the sensitivity of tropical rainforest ecosystems to eCO­2 is largely unknown even though the importance of tropical forests for biodiversity, carbon storage and regional and global climate feedbacks is unambiguously recognized. The AmazonFACE (Free-Air Carbon Enrichment) project will be the first ecosystem scale eCO2 experiment undertaken in the tropics, as well as the first to be undertaken in a mature forest. AmazonFACE provides the opportunity to integrate ecosystem modeling with experimental observations right from the beginning of the experiment, harboring a two-way exchange, i.e. models provide hypotheses to be tested, and observations deliver the crucial data to test and improve ecosystem models. We present preliminary exploration of observed and expected process responses to eCO2 at the AmazonFACE site from the dynamic global vegetation model LPJ-GUESS, highlighting opportunities and pitfalls for model integration of tropical FACE experiments. The preliminary analysis provides baseline hypotheses, which are to be further developed with a follow-up multiple model inter-comparison. The analysis builds on the recently undertaken FACE-MDS (Model-Data Synthesis) project, which was applied to two temperate FACE experiments and exceeds the traditional focus on comparing modeled end-target output. The approach has proven successful in identifying well (and less well) represented processes in models, which are separated for six clusters also here; (1) Carbon fluxes, (2) Carbon pools, (3) Energy balance, (4) Hydrology, (5) Nutrient cycling, and (6) Population dynamics. Simulation performance of observed conditions at the AmazonFACE site (a.o. from Manaus K34 eddy flux tower) will highlight process-based model deficiencies, and aid the separation of uncertainties arising from general ecosystem responses and those responses related to eCO2.

Tropical forest response to elevated CO2: Model-experiment integration at the AmazonFACE site.

NASA Astrophysics Data System (ADS)

Fleischer, K.

2015-12-01

The terrestrial biosphere's response to current and future elevated atmospheric carbon dioxide (eCO2) is a large source of uncertainty in future projections of the C cycle, climate and ecosystem functioning. In particular, the sensitivity of tropical rainforest ecosystems to eCO­2 is largely unknown even though the importance of tropical forests for biodiversity, carbon storage and regional and global climate feedbacks is unambiguously recognized. The AmazonFACE (Free-Air Carbon Enrichment) project will be the first ecosystem scale eCO2 experiment undertaken in the tropics, as well as the first to be undertaken in a mature forest. AmazonFACE provides the opportunity to integrate ecosystem modeling with experimental observations right from the beginning of the experiment, harboring a two-way exchange, i.e. models provide hypotheses to be tested, and observations deliver the crucial data to test and improve ecosystem models. We present preliminary exploration of observed and expected process responses to eCO2 at the AmazonFACE site from the dynamic global vegetation model LPJ-GUESS, highlighting opportunities and pitfalls for model integration of tropical FACE experiments. The preliminary analysis provides baseline hypotheses, which are to be further developed with a follow-up multiple model inter-comparison. The analysis builds on the recently undertaken FACE-MDS (Model-Data Synthesis) project, which was applied to two temperate FACE experiments and exceeds the traditional focus on comparing modeled end-target output. The approach has proven successful in identifying well (and less well) represented processes in models, which are separated for six clusters also here; (1) Carbon fluxes, (2) Carbon pools, (3) Energy balance, (4) Hydrology, (5) Nutrient cycling, and (6) Population dynamics. Simulation performance of observed conditions at the AmazonFACE site (a.o. from Manaus K34 eddy flux tower) will highlight process-based model deficiencies, and aid the separation of uncertainties arising from general ecosystem responses and those responses related to eCO2.

Adapting public policy theory for public health research: A framework to understand the development of national policies on global health.

PubMed

Jones, Catherine M; Clavier, Carole; Potvin, Louise

2017-03-01

National policies on global health appear as one way that actors from health, development and foreign affairs sectors in a country coordinate state action on global health. Next to a burgeoning literature in which international relations and global governance theories are employed to understand global health policy and global health diplomacy at the international level, little is known about policy processes for global health at the national scale. We propose a framework of the policy process to understand how such policies are developed, and we identify challenges for public health researchers integrating conceptual tools from political science. We developed the framework using a two-step process: 1) reviewing literature to establish criteria for selecting a theoretical framework fit for this purpose, and 2) adapting Real-Dato's synthesis framework to integrate a cognitive approach to public policy within a constructivist perspective. Our framework identifies multiple contexts as part of the policy process, focuses on situations where actors work together to make national policy on global health, considers these interactive situations as spaces for observing external influences on policy change and proposes policy design as the output of the process. We suggest that this framework makes three contributions to the conceptualisation of national policy on global health as a research object. First, it emphasizes collective action over decisions of individual policy actors. Second, it conceptualises the policy process as organised interactive spaces for collaboration rather than as stages of a policy cycle. Third, national decision-making spaces are opportunities for transferring ideas and knowledge from different sectors and settings, and represent opportunities to identify international influences on a country's global health policy. We discuss two sets of challenges for public health researchers using interdisciplinary approaches in policy research. Copyright © 2017 Elsevier Ltd. All rights reserved.

Reducing neurodevelopmental disorders and disability through research and interventions.

PubMed

Boivin, Michael J; Kakooza, Angelina M; Warf, Benjamin C; Davidson, Leslie L; Grigorenko, Elena L

2015-11-19

We define neurodevelopment as the dynamic inter-relationship between genetic, brain, cognitive, emotional and behavioural processes across the developmental lifespan. Significant and persistent disruption to this dynamic process through environmental and genetic risk can lead to neurodevelopmental disorders and disability. Research designed to ameliorate neurodevelopmental disorders in low- and middle-income countries, as well as globally, will benefit enormously from the ongoing advances in understanding their genetic and epigenetic causes, as modified by environment and culture. We provide examples of advances in the prevention and treatment of, and the rehabilitation of those with, neurodevelopment disorders in low- and middle-income countries, along with opportunities for further strategic research initiatives. Our examples are not the only possibilities for strategic research, but they illustrate problems that, when solved, could have a considerable impact in low-resource settings. In each instance, research in low- and middle-income countries led to innovations in identification, surveillance and treatment of a neurodevelopmental disorder. These innovations have also been integrated with genotypic mapping of neurodevelopmental disorders, forming important preventative and rehabilitative interventions with the potential for high impact. These advances will ultimately allow us to understand how epigenetic influences shape neurodevelopmental risk and resilience over time and across populations. Clearly, the most strategic areas of research opportunity involve cross-disciplinary integration at the intersection between the environment, brain or behaviour neurodevelopment, and genetic and epigenetic science. At these junctions a robust integrative cross-disciplinary scientific approach is catalysing the creation of technologies and interventions for old problems. Such approaches will enable us to achieve and sustain the United Nations moral and legal mandate for child health and full development as a basic global human right.

Concept formation: a supportive process for early career nurses.

PubMed

Thornley, Tracey; West, Sandra

2010-09-01

Individuals come to understand abstract constructs such as that of the 'expert' through the formation of concepts. Time and repeated opportunity for observation to support the generalisation and abstraction of the developing concept are essential if the concept is to form successfully. Development of an effective concept of the 'expert nurse' is critical for early career nurses who are attempting to integrate theory, values and beliefs as they develop their clinical practice. This study explores the use of a concept development framework in a grounded theory study of the 'expert nurse'. Qualitative. Using grounded theory methods for data collection and analysis, semi-structured interviews were conducted with registered nurses. The participants were asked to describe their concept of the 'expert nurse' and to discuss their experience of developing this. Participants reported forming their concept of the 'expert nurse', after multiple opportunities to engage with nurses identified as 'expert'. This identification did not necessarily relate to the designated position of the 'expert nurse' or assigned mentors. When the early career nurse does not successfully form a concept of the 'expert nurse', difficulties in personal and professional development including skill/knowledge development may arise. To underpin development of their clinical practice effectively, early career nurses need to be provided with opportunities that facilitate the purposive formation of their own concept of the 'expert nurse'. Formation of this concept is not well supported by the common practice of assigning mentors. Early career nurses must be provided with the time and the opportunity to individually develop and refine their concept of the 'expert nurse'. To achieve this, strategies including providing opportunities to engage with expert nurses and discussion of the process of concept formation and its place in underpinning personal judgments may be of assistance. © 2010 Blackwell Publishing Ltd.

The rhetoric and realities of integrating air quality into the local transport planning process in English local authorities.

PubMed

Olowoporoku, Dotun; Hayes, Enda; Longhurst, James; Parkhurst, Graham

2012-06-30

Regardless of its intent and purposes, the first decade of the Local Air Quality Management (LAQM) framework had little or no effect in reducing traffic-related air pollution in the UK. Apart from the impact of increased traffic volumes, the major factor attributed to this failure is that of policy disconnect between the process of diagnosing air pollution and its management, thereby limiting the capability of local authorities to control traffic-related sources of air pollution. Integrating air quality management into the Local Transport Plan (LTP) process therefore presents opportunities for enabling political will, funding and joined-up policy approach to reduce this limitation. However, despite the increased access to resources for air quality measures within the LTP process, there are local institutional, political and funding constraints which reduce the impact of these policy interventions on air quality management. This paper illustrate the policy implementation gaps between central government policy intentions and the local government process by providing evidence of the deprioritisation of air quality management compared to the other shared priorities in the LTP process. We draw conclusions on the policy and practice of integrating air quality management into transport planning. The evidence thereby indicate the need for a policy shift from a solely localised hotspot management approach, in which the LAQM framework operates, to a more holistic management of vehicular emissions within wider spatial administrative areas. Copyright © 2012 Elsevier Ltd. All rights reserved.

Nouvelle methode d'integration energetique pour la retro-installation des procedes industriels et la transformation des usines papetieres

NASA Astrophysics Data System (ADS)

Bonhivers, Jean-Christophe

The increase in production of goods over the last decades has led to the need for improving the management of natural resources management and the efficiency of processes. As a consequence, heat integration methods for industry have been developed. These have been successful for the design of new plants: the integration principles are largely employed, and energy intensity has dramatically decreased in many processes. Although progress has also been achieved in integration methods for retrofit, these methods still need further conceptual development. Furthermore, methodological difficulties increase when trying to retrofit heat exchange networks that are closely interrelated to water networks, such as the case of pulp and paper mills. The pulp and paper industry seeks to increase its profitability by reducing production costs and optimizing supply chains. Recent process developments in forestry biorefining give this industry the opportunity for diversification into bio-products, increasing potential profit margins, and at the same time modernizing its energy systems. Identification of energy strategies for a mill in a changing environment, including the possibility of adding a biorefinery process on the industrial site, requires better integration methods for retrofit situations. The objective of this thesis is to develop an energy integration method for the retrofit of industrial systems and the transformation of pulp and paper mills, ant to demonstrate the method in case studies. Energy is conserved and degraded in a process. Heat can be converted into electricity, stored as chemical energy, or rejected to the environment. A systematic analysis of successive degradations of energy between the hot utilities until the environment, through process operations and existing heat exchangers, is essential in order to reduce the heat consumption. In this thesis, the "Bridge Method" for energy integration by heat exchanger network retrofit has been developed. This method is the first that considers the analysis of these degradations. The fundamental mechanism to reduce the heat consumption in an existing network has been made explicit; it is the basis of the developed method. The Bridge Method includes the definition of "a bridge", which is a set of modifications leading to heat reduction in a heat exchanger network. It is proven that, for a given set of streams, only bridges can lead to heat savings. The Bridge Method also includes (1) a global procedure for heat exchanger network retrofit, (2) a procedure to enumerate systematically the bridges, (3) "a network table" to easily evaluate them, and (4) an "energy transfer diagram" showing the effect of the two first principles of thermodynamics of energy conservation and degradation in industrial processes in order to identify energy savings opportunities. The Bridge Method can be used for the analysis of networks including several types of heat transfer, and site-wide analysis. The Bridge Method has been applied in case studies for retrofitting networks composed of indirect-contact heat exchangers, including the network of a kraft pulp mill, and also networks of direct-contact heat exchangers, including the hot water production system of a pulp mill. The method has finally been applied for the evaluation of a biorefinery process, alone or hosted in a kraft pulp mill. Results show that the use of the method significantly reduces the search space and leads to identification of the relevant solutions. The necessity of a bridge to reduce the inputs and outputs of a process is a consequence of the two first thermodynamics principles of energy conservation and increase in entropy. The concept of bridge alone can also be used as a tool for process analysis, and in numerical optimization-based approaches for energy integration.

Energy-Water System Solutions | Energy Analysis | NREL

Science.gov Websites

simultaneously. Example Projects Energy, water, and renewable opportunities assessment at Bagram Air Force Base opportunity to plan integrated infrastructure. Example Projects Identification of critical water and campus-level opportunities. Example Projects Net Zero Energy-Water-Waste analysis for Fort Carson Net

Comparing and integrating multiple data source for 3D surface reconstruction of Alpine Glaciers

NASA Astrophysics Data System (ADS)

Scaioni, Marco; Fugazza, Davide; Diolaiuti, Guglielmina Adele; Cernuschi, Massimo; Corti, Manuel

2017-04-01

Alpine glaciers are generally undergoing a fast and complex process leading to the reduction of the ice mass. Monitoring this process from a quantitative and qualitative point-of-view is of great importance for understanding the related dynamics and to apply proper numerical models. While the analysis of archive maps, medium resolution satellite images and DEM's may provide an overview of the long-term processes, the application of close-range sensing techniques offers the unprecedented opportunity to operate a 4D reconstruction of the glacier geometry. Terrestrial sensors technologies (Long and Very-long Range TLS and SfM Photogrammetry) integrated to UAV Photogrammetry may offer a complete view of the dynamical evolution of a glacier, reaching a high spatial and temporal resolution. Up until today, not many cases exist where a long-term archive of 4D high-resolution data has been established, limiting the chance to understand and to model the undergoing physical processes. The goal of the research presented here is to collect a set of multi-temporal data sets of the lower part of the Forni Glacier, in the National Stelvio Park, Italy. The first data acquisition campaign was carried out during August 2016, to be followed on yearly regular-basis. This will give the researchers the opportunity to analyse 4D data describing in detail the disruption of the glacier and its dramatic retreat. These data sets could be compared to DEM's acquired in the past by using UAV-Photogrammetry (2014) and traditional stereo-photogrammetry (2007). In addition, the presence of additional hydrological and meteorological data can be exploited in the analyses. The first data acquisition campaign has also given the opportunity to investigate the data acquisition methodology. The UAV flight has revealed to output a complete overview of the glacier surface in terms of DEM and orthophoto. Thanks to the photogrammetric process and the use of seven GNSS-GCPs, a high resolution has been obtained (about 102 pts/m2). The presence of vertical and sub-vertical surfaces has motivated the use of terrestrial sensors. The integration of sensors from ground and from drones has allowed to better describe some local physical processes (i.e., opening of crevasses, ice tunnelling, local collapses) that are giving an impressive contribution to the loss of ice bulk. This processes require a detail 3D modelling to be investigated, calling for the use of sensors able to reconstruct also the vertical and sub-vertical faces, thus using a ground-based standpoint. To this purpose, the adoption of SfM-Photogrammetry has yielded results comparable to the ones achieved using a long-range TLS Riegl LMS-Z420i, which can be assumed as benchmarking for accuracy assessment, but being more cumbersome and difficult to be operated in the glacier area. The measurement of GCPs for the terrestrial photogrammetric project reveal to be a complex task, involving the need of a total station. For this reason, the integration of GNSS and cameras will be developed for the future measurement sessions. The effect of block geometry on the final output has also been investigated for SfM-Photogrammetry, considering the severe limitations implied in the Alpine environment.

Quality-of-care research in mental health: responding to the challenge.

PubMed

McGlynn, E A; Norquist, G S; Wells, K B; Sullivan, G; Liberman, R P

1988-01-01

Quality-of-care research in mental health is in the developmental stages, which affords an opportunity to take an integrative approach, building on principles from efficacy, effectiveness, quality assessment, and quality assurance research. We propose an analytic strategy for designing research on the quality of mental health services using an adaptation of the structure, process, and outcome classification scheme. As a concrete illustration of our approach, we discuss research on a particular target population-patients with chronic schizophrenia. Future research should focus on developing models of treatment, establishing criteria and standards for outcomes and processes, and gathering data on community practices.

Keeping genome organized creates opportunities for damage | Center for Cancer Research

Cancer.gov

Packing an entire genome inside the cramped quarters of a cell nucleus can put chromosomes at risk for damage, according to new research led by André Nussenzweig, Ph.D., Chief of CCR’s Laboratory of Genomic Integrity. The findings, reported July 20, 2017, in Cell, suggest that DNA breaks are routinely introduced and then repaired as a cell folds and organizes its genome, and that when repair processes fail, these breaks can give rise to chromosomal abnormalities characteristic of cancer cells. 

Cloud Based Metalearning System for Predictive Modeling of Biomedical Data

PubMed Central

Vukićević, Milan

2014-01-01

Rapid growth and storage of biomedical data enabled many opportunities for predictive modeling and improvement of healthcare processes. On the other side analysis of such large amounts of data is a difficult and computationally intensive task for most existing data mining algorithms. This problem is addressed by proposing a cloud based system that integrates metalearning framework for ranking and selection of best predictive algorithms for data at hand and open source big data technologies for analysis of biomedical data. PMID:24892101

ERP System Implementation: An Oil and Gas Exploration Sector Perspective

NASA Astrophysics Data System (ADS)

Mishra, Alok; Mishra, Deepti

Enterprise Resource Planning (ERP) systems provide integration and optimization of various business processes which leads to improved planning and decision quality, smoother coordination between business units resulting in higher efficiency, and quicker response time to customer demands and inquiries. This paper reports challenges, opportunities and outcome of ERP implementation in Oil & Gas exploration sector. This study will facilitate in understanding transition, constraints and implementation of ERP in this sector and also provide guidelines from lessons learned in this regard.

Advances in welding science: A perspective

NASA Astrophysics Data System (ADS)

David, S. A.; Vitek, J. M.; Babu, S. S.; Debroy, T.

The ultimate goal of welding technology is to improve the joint integrity and increase productivity. Over the years, welding has been more of an art than a science, but in the last few decades major advances have taken place in welding science and technology. With the development of new methodologies at the crossroads of basic and applied sciences, enormous opportunities and potential exist to develop a science-based tailoring of composition, structure, and properties of welds with intelligent control and automation of the welding processes.

UNL

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aptekar, Alexander

The final report on New York City College of Technology (City Tech) DURA (Diverse | Urban | Resilient | Adaptable) home project. City Tech has participated in the Solar Decathlon 2015 project as DURA. The DURA team consists of students, faculty, volunteers, Service Corps participants, Industry advisers, recent graduates and others. The DURA team researched, designed, and constructed a zero energy prototype house. This process was a valuable opportunity for City Tech as a project of such scale has not been completed before with the integration of so many departments and their students.

Current realities and future vision: Developing an interprofessional, integrated health care workforce.

PubMed

Dubus, Nicole; Howard, Heather

2016-10-01

This article shares findings from an interprofessional symposium that took place in Boston in the spring of 2015. Educators and practitioners from various disciplines shared challenges, successes, and ideas on best interprofessional collaboration (IPC) and curricula development. The findings include the importance of patient-and-family-centered care, which includes the patient and his/her family in the decision-making process; increased education regarding IPC in universities and major hospitals; and educational opportunities within health care systems.

Space Station services and design features for users

NASA Technical Reports Server (NTRS)

Kurzhals, Peter R.; Mckinney, Royce L.

1987-01-01

The operational design features and services planned for the NASA Space Station will furnish, in addition to novel opportunities and facilities, lower costs through interface standardization and automation and faster access by means of computer-aided integration and control processes. By furnishing a basis for large-scale space exploitation, the Space Station will possess industrial production and operational services capabilities that may be used by the private sector for commercial ventures; it could also ultimately support lunar and planetary exploration spacecraft assembly and launch facilities.

Integrated Clinical Information System Collaboration Project (CPOE)

DTIC Science & Technology

2009-10-01

variation in care, represents an extraordinary opportunity to  positively  impact  current and future quality outcomes.      General  Patient  Outcomes...those of the author(s) and should not be construed as an official Department of the Army position , policy or decision unless so designated by...process for submitting orders. This study examined the impact of the transition from paper order entry to CPOE on patient care by the adoption of

Application studies of RFID technology in the process of coal logistics transport

NASA Astrophysics Data System (ADS)

Qiao, Bingqin; Chang, Xiaoming; Hao, Meiyan; Kong, Dejin

2012-04-01

For quality control problems in coal transport, RFID technology has been proposed to be applied to coal transportation process. The whole process RFID traceability system from coal production to consumption has been designed and coal supply chain logistics tracking system integration platform has been built, to form the coal supply chain traceability and transport tracking system and providing more and more transparent tracking and monitoring of coal quality information for consumers of coal. Currently direct transport and combined transport are the main forms of coal transportation in China. The means of transport are cars, trains and ships. In the booming networking environment of RFID technology, the RFID technology will be applied to coal logistics and provide opportunity for the coal transportation tracking in the process transportation.

Psychoimmuno-neuroendocrinology: An integrative approach to modern philosophy in medicine and psychology.

PubMed

Fedor-Freybergh, Peter G.

1999-01-01

The immune system is now seen to be closely integrated with other physiological circuits, such as the central nervous system (CNS) and the neuroendocrine system. There is also an increasing amount of evidence that this integrated circuit is bidirectional and both systems exert a reciprocal effect on each other. We have always stressed the interdisciplinary nature of the science where disciplines and sciences such as medicine, biochemistry, genetics, psychology, human ethology, etc. meet and undergo a process of "cross-fertilization." We also have stressed the indivisibility of the somatic and psychological processes in the indivisible continuum of human life from its very beginning and the inseparability of the development and functions of the central nervous system and the immunological and neuroendocrine processes. This transdisciplinary and integrative aspect of sciences and their entree in the twenty-first century is the true vision for our common efforts. Integration means also amalgamation, assimilation, blending, combining, incorporation, unification and harmony. This last mentioned, harmony, should be stressed and underlined specifically: a harmony between different views and approaches, between different methods and methodologies, different theories and practices. In order to undertake such a challenge, a new scientific theory and a common language is required, a language that would be understood across disciplines and would be able to assist in getting beyond semantic problems. The bridge between the immune system, neuroendocrinology and the rest of the central nervous system opens the gateway to more common understanding and acceptance across the disciplines. It is an umbrella for the endeavor that unites various scientific fields in their attempt to elucidate the processes of experience involved from the earliest stages of human life. This integration does cross over the different disciplines and diagnostic systems. It attaches theoretical and applied fields, basic research and clinical experience throughout the whole continuity of human life from conception and onwards. Integrated Psychoimmuno-Neuroendocrinology represents a unique opportunity for the primary prevention of psychological, emotional and physical disorders.

Lessons Learned from Accelerating Opportunity. Lessons Learned Series

ERIC Educational Resources Information Center

Wilson, Randall

2015-01-01

The Accelerating Opportunity initiative helps our nation's lowest-skilled adults earn college credentials and enter higher-wage jobs faster by combining the Adult Basic Education and career and technical training they need into one integrated curriculum. Based on four years of designing and managing Accelerating Opportunity, Jobs for the Future…

Opportunities and Examples for Integration of Socio-environmental Approaches to Support Climate-informed Decisions

NASA Astrophysics Data System (ADS)

Kenney, M. A.

2014-12-01

Climate and environmental decisions require science that couples human and natural systems to quantify or articulate the observed physical, natural, and societal changes or likely consequences of different decision options. Despite the need for such policy-relevant research, multidisciplinary collaborations can be wrought with challenges of data integration, model interoperability, and communication across disciplinary divides. In this talk, I will present several examples where I have collaborated with colleagues from the physical, natural, and social sciences to develop novel, actionable science to inform decision-making. Specifically, I will discuss a cost analysis of water and sediment diversions to optimize land building in the Mississippi River delta (winner of American Geophysical Union Water Resources Research Editor's Choice Award 2014) and the development of a National Climate Indicator System that uses knowledge across the physical, natural, and social sciences to establish an end-to-end indicator system of climate changes, impacts, vulnerabilities, and responses. The latter project is in the process of moving from research to operations, an additional challenge and opportunity, as we work with the U.S. Global Change Research Program and their affiliated Federal agencies to establish it beyond the research prototype. Using these examples, I will provide some lessons learned that would have general applicability to socio-environmental research collaborations and integration of data, models, and information systems to support climate and environmental decision-making.

Integrated health messaging for multiple neglected zoonoses: Approaches, challenges and opportunities in Morocco.

PubMed

Ducrotoy, M J; Yahyaoui Azami, H; El Berbri, I; Bouslikhane, M; Fassi Fihri, O; Boué, F; Petavy, A F; Dakkak, A; Welburn, S; Bardosh, K L

2015-12-01

Integrating the control of multiple neglected zoonoses at the community-level holds great potential, but critical data is missing to inform the design and implementation of different interventions. In this paper we present an evaluation of an integrated health messaging intervention, using powerpoint presentations, for five bacterial (brucellosis and bovine tuberculosis) and dog-associated (rabies, cystic echinococcosis and leishmaniasis) zoonotic diseases in Sidi Kacem Province, northwest Morocco. Conducted by veterinary and epidemiology students between 2013 and 2014, this followed a process-based approach that encouraged sequential adaptation of images, key messages, and delivery strategies using auto-evaluation and end-user feedback. We describe the challenges and opportunities of this approach, reflecting on who was targeted, how education was conducted, and what tools and approaches were used. Our results showed that: (1) replacing words with local pictures and using "hands-on" activities improved receptivity; (2) information "overload" easily occurred when disease transmission pathways did not overlap; (3) access and receptivity at schools was greater than at the community-level; and (4) piggy-backing on high-priority diseases like rabies offered an important avenue to increase knowledge of other zoonoses. We conclude by discussing the merits of incorporating our validated education approach into the school curriculum in order to influence long-term behaviour change. Copyright © 2015 Elsevier B.V. All rights reserved.

Movement integration in elementary classrooms: Teacher perceptions and implications for program planning.

PubMed

Webster, Collin A; Zarrett, Nicole; Cook, Brittany S; Egan, Cate; Nesbitt, Danielle; Weaver, R Glenn

2017-04-01

Movement integration (MI), which involves infusing physical activity (PA) into regular classroom time in schools, is widely recommended to help children meet the national guideline of 60min of PA each day. Understanding the perspective of elementary classroom teachers (ECTs) toward MI is critical to program planning for interventions/professional development. This study examined the MI perceptions of ECTs in order to inform the design and implementation of a school-based pilot program that focused in part on increasing children's PA through MI. Twelve ECTs (Grades 1-3) from four schools were selected to participate based on their responses to a survey about their use of MI. Based on the idea that MI programming should be designed with particular attention to teachers who integrate relatively few movement opportunities in their classrooms, the intent was to select the teacher who reported integrating movement the least at her/his respective grade level at each school. However, not all of these teachers agreed to participate in the study. The final sample included two groups of ECTs, including eight lowest integrating teachers and four additional teachers. Each ECT participated in an interview during the semester before the pilot program was implemented. Through qualitative analysis of the interview transcripts, four themes emerged: (a) challenges and barriers (e.g., lack of time), (b) current and ideal resources (e.g., school support), (c) current implementation processes (e.g., scheduling MI into daily routines), and (e) teachers' ideas and tips for MI (e.g., stick with it and learn as you go). The themes were supported by data from both groups of teachers. This study's findings can inform future efforts to increase movement opportunities for children during regular classroom time. Copyright © 2017 Elsevier Ltd. All rights reserved.

The Role Of Management Of The Field-Forest Boundary In Poland's Process Of Agricultural Restructuring

NASA Astrophysics Data System (ADS)

Woch, Franciszek; Borek, Robert

2015-01-01

The aim of the work described here has been to point to the relationships between the field-forest boundary and crop productivity as regards the present agrarian land-use structure in Poland, and to provide new opportunities for arranging the agrarian process and the spatial planning of the rural landscape in the context of the sustainable shaping of the field-forest boundary. Impacts of forests and woodlands on crop productivity have been assessed using available data from relevant Polish literature. An assessment of the plot-distribution pattern characterising farms in Poland was made on the basis of reference data from the Agency for the Restructuring and Modernisation of Agriculture. Finally, the possibility of afforestation of agricultural land has been evaluated within the existing legal framework, and on the basis of available data, with attention paid to the need to include organization of the field-forest boundary within the comprehensive management and planning of rural areas, and to preserve woody elements in patchy landscapes. This all creates an opportunity to test innovative approaches to integrated land use which combines the creation of public goods and local products based on participatory learning processes that bring in local stakeholders and decision-makers.

Challenges in Biomarker Discovery: Combining Expert Insights with Statistical Analysis of Complex Omics Data

PubMed Central

McDermott, Jason E.; Wang, Jing; Mitchell, Hugh; Webb-Robertson, Bobbie-Jo; Hafen, Ryan; Ramey, John; Rodland, Karin D.

2012-01-01

Introduction The advent of high throughput technologies capable of comprehensive analysis of genes, transcripts, proteins and other significant biological molecules has provided an unprecedented opportunity for the identification of molecular markers of disease processes. However, it has simultaneously complicated the problem of extracting meaningful molecular signatures of biological processes from these complex datasets. The process of biomarker discovery and characterization provides opportunities for more sophisticated approaches to integrating purely statistical and expert knowledge-based approaches. Areas covered In this review we will present examples of current practices for biomarker discovery from complex omic datasets and the challenges that have been encountered in deriving valid and useful signatures of disease. We will then present a high-level review of data-driven (statistical) and knowledge-based methods applied to biomarker discovery, highlighting some current efforts to combine the two distinct approaches. Expert opinion Effective, reproducible and objective tools for combining data-driven and knowledge-based approaches to identify predictive signatures of disease are key to future success in the biomarker field. We will describe our recommendations for possible approaches to this problem including metrics for the evaluation of biomarkers. PMID:23335946

Challenges in Biomarker Discovery: Combining Expert Insights with Statistical Analysis of Complex Omics Data

DOE Office of Scientific and Technical Information (OSTI.GOV)

McDermott, Jason E.; Wang, Jing; Mitchell, Hugh D.

2013-01-01

The advent of high throughput technologies capable of comprehensive analysis of genes, transcripts, proteins and other significant biological molecules has provided an unprecedented opportunity for the identification of molecular markers of disease processes. However, it has simultaneously complicated the problem of extracting meaningful signatures of biological processes from these complex datasets. The process of biomarker discovery and characterization provides opportunities both for purely statistical and expert knowledge-based approaches and would benefit from improved integration of the two. Areas covered In this review we will present examples of current practices for biomarker discovery from complex omic datasets and the challenges thatmore » have been encountered. We will then present a high-level review of data-driven (statistical) and knowledge-based methods applied to biomarker discovery, highlighting some current efforts to combine the two distinct approaches. Expert opinion Effective, reproducible and objective tools for combining data-driven and knowledge-based approaches to biomarker discovery and characterization are key to future success in the biomarker field. We will describe our recommendations of possible approaches to this problem including metrics for the evaluation of biomarkers.« less

Sequencing Data Discovery and Integration for Earth System Science with MetaSeek

NASA Astrophysics Data System (ADS)

Hoarfrost, A.; Brown, N.; Arnosti, C.

2017-12-01

Microbial communities play a central role in biogeochemical cycles. Sequencing data resources from environmental sources have grown exponentially in recent years, and represent a singular opportunity to investigate microbial interactions with Earth system processes. Carrying out such meta-analyses depends on our ability to discover and curate sequencing data into large-scale integrated datasets. However, such integration efforts are currently challenging and time-consuming, with sequencing data scattered across multiple repositories and metadata that is not easily or comprehensively searchable. MetaSeek is a sequencing data discovery tool that integrates sequencing metadata from all the major data repositories, allowing the user to search and filter on datasets in a lightweight application with an intuitive, easy-to-use web-based interface. Users can save and share curated datasets, while other users can browse these data integrations or use them as a jumping off point for their own curation. Missing and/or erroneous metadata are inferred automatically where possible, and where not possible, users are prompted to contribute to the improvement of the sequencing metadata pool by correcting and amending metadata errors. Once an integrated dataset has been curated, users can follow simple instructions to download their raw data and quickly begin their investigations. In addition to the online interface, the MetaSeek database is easily queryable via an open API, further enabling users and facilitating integrations of MetaSeek with other data curation tools. This tool lowers the barriers to curation and integration of environmental sequencing data, clearing the path forward to illuminating the ecosystem-scale interactions between biological and abiotic processes.

Early Child Development and Nutrition: A Review of the Benefits and Challenges of Implementing Integrated Interventions.

PubMed

Hurley, Kristen M; Yousafzai, Aisha K; Lopez-Boo, Florencia

2016-03-01

Poor nutrition (substandard diet quantity and/or quality resulting in under- or overnutrition) and the lack of early learning opportunities contribute to the loss of developmental potential and life-long health and economic disparities among millions of children aged <5 y. Single-sector interventions representing either early child development (ECD) or nutrition have been linked to positive child development and/or nutritional status, and recommendations currently advocate for the development and testing of integrated interventions. We reviewed the theoretical and practical benefits and challenges of implementing integrated nutrition and ECD interventions along with the evidence for best practice and benefit-cost and concluded that the strong theoretical rationale for integration is more nuanced than the questions that the published empirical evidence have addressed. For example, further research is needed to 1) answer questions related to how integrated messaging influences caregiver characteristics such as well-being, knowledge, and behavior and how these influence early child nutrition and development outcomes; 2) understand population and nutritional contexts in which integrated interventions are beneficial; and 3) explore how varying implementation processes influence the efficacy, uptake, and cost-benefit of integrated nutrition and ECD interventions. © 2016 American Society for Nutrition.

Early Child Development and Nutrition: A Review of the Benefits and Challenges of Implementing Integrated Interventions1234

PubMed Central

Hurley, Kristen M; Yousafzai, Aisha K; Lopez-Boo, Florencia

2016-01-01

Poor nutrition (substandard diet quantity and/or quality resulting in under- or overnutrition) and the lack of early learning opportunities contribute to the loss of developmental potential and life-long health and economic disparities among millions of children aged <5 y. Single-sector interventions representing either early child development (ECD) or nutrition have been linked to positive child development and/or nutritional status, and recommendations currently advocate for the development and testing of integrated interventions. We reviewed the theoretical and practical benefits and challenges of implementing integrated nutrition and ECD interventions along with the evidence for best practice and benefit-cost and concluded that the strong theoretical rationale for integration is more nuanced than the questions that the published empirical evidence have addressed. For example, further research is needed to 1) answer questions related to how integrated messaging influences caregiver characteristics such as well-being, knowledge, and behavior and how these influence early child nutrition and development outcomes; 2) understand population and nutritional contexts in which integrated interventions are beneficial; and 3) explore how varying implementation processes influence the efficacy, uptake, and cost-benefit of integrated nutrition and ECD interventions. PMID:26980819

'Are we there yet?' - operationalizing the concept of Integrated Public Health Policies.

PubMed

Hendriks, Anna-Marie; Habraken, Jolanda; Jansen, Maria W J; Gubbels, Jessica S; De Vries, Nanne K; van Oers, Hans; Michie, Susan; Atkins, L; Kremers, Stef P J

2014-02-01

Although 'integrated' public health policies are assumed to be the ideal way to optimize public health, it remains hard to determine how far removed we are from this ideal, since clear operational criteria and defining characteristics are lacking. A literature review identified gaps in previous operationalizations of integrated public health policies. We searched for an approach that could fill these gaps. We propose the following defining characteristics of an integrated policy: (1) the combination of policies includes an appropriate mix of interventions that optimizes the functioning of the behavioral system, thus ensuring that motivation, capability and opportunity interact in such a way that they promote the preferred (health-promoting) behavior of the target population, and (2) the policies are implemented by the relevant policy sectors from different policy domains. Our criteria should offer added value since they describe pathways in the process towards formulating integrated policy. The aim of introducing our operationalization is to assist policy makers and researchers in identifying truly integrated cases. The Behavior Change Wheel proved to be a useful framework to develop operational criteria to assess the current state of integrated public health policies in practice. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

Integration Process for the Habitat Demonstration Unit

NASA Technical Reports Server (NTRS)

Gill, Tracy; Merbitz, Jerad; Kennedy, Kriss; Tri, Terry; Howe, A. Scott

2010-01-01

The Habitat Demonstration Unit (HDU) is an experimental exploration habitat technology and architecture test platform designed for analog demonstration activities The HDU project has required a team to integrate a variety of contributions from NASA centers and outside collaborators and poses a challenge in integrating these disparate efforts into a cohesive architecture To complete the development of the HDU from conception in June 2009 to rollout for operations in July 2010, a cohesive integration strategy has been developed to integrate the various systems of HDU and the payloads, such as the Geology Lab, that those systems will support The utilization of interface design standards and uniquely tailored reviews have allowed for an accelerated design process Scheduled activities include early fit-checks and the utilization of a Habitat avionics test bed prior to equipment installation into HDU A coordinated effort to utilize modeling and simulation systems has aided in design and integration concept development Modeling tools have been effective in hardware systems layout, cable routing and length estimation, and human factors analysis Decision processes on the shell development including the assembly sequence and the transportation have been fleshed out early on HDU to maximize the efficiency of both integration and field operations Incremental test operations leading up to an integrated systems test allows for an orderly systems test program The HDU will begin its journey as an emulation of a Pressurized Excursion Module (PEM) for 2010 field testing and then may evolve to a Pressurized Core Module (PCM) for 2011 and later field tests, depending on agency architecture decisions The HDU deployment will vary slightly from current lunar architecture plans to include developmental hardware and software items and additional systems called opportunities for technology demonstration One of the HDU challenges has been designing to be prepared for the integration of presently unanticipated systems Results of the HDU field tests will influence future designs of habitat systems.

CMOS compatible IR sensors by cytochrome c protein

NASA Astrophysics Data System (ADS)

Liao, Chien-Jen; Su, Guo-Dung

2013-09-01

In recent years, due to the progression of the semiconductor industrial, the uncooled Infrared sensor - microbolometer has opened the opportunity for achieving low cost infrared imaging systems for both military and commercial applications. Therefore, various fabrication processes and different materials based microbolometer have been developed sequentially. The cytochrome c (protein) thin film has be reported high temperature coefficient of resistance (TCR), which is related to the performance of microbolometer directly. Hence the superior TCR value will increase the performance of microbolometer. In this paper, we introduced a novel fabrication process using aluminum which is compatible with the Taiwan Semiconductor Manufacture Company (TSMC) D35 2P4M process as the main structure material, which benefits the device to integrate with readout integrated circuit (ROIC).The aluminum split structure is suspended by sacrificial layer utilizing the standard photolithography technology and chemical etching. The height and thickness of the structure are already considered. Besides, cytochrome c solutions were ink-jetted onto the aluminum structure by using the inkjet printer, applying precise control of the Infrared absorbing layer. In measurement, incident Infrared radiation can be detected and later the heat can be transmitted to adjacent pads to readout the signal. This approach applies an inexpensive and simple fabrication process and makes the device suitable for integration. In addition, the performance can be further improved with low noise readout circuits.

Self-determination theory and romantic relationship processes.

PubMed

Knee, C Raymond; Hadden, Benjamin W; Porter, Ben; Rodriguez, Lindsey M

2013-11-01

Self-determination theory can be viewed as a theory of optimal relationship development and functioning. We examine the concept of self that is employed in self-determination theory and explain how its unique definition allows an important and novel characterization of investing one's "self" in romantic relationships. A self-determined perspective on romantic relationships integrates several theories on romantic relationship development, but also goes beyond them by explicitly articulating the personality, developmental, and situational factors that facilitate optimal self-investment and relational functioning. Self-determination promotes openness rather than defensiveness and facilitates perspective-taking, authenticity, and support of close others. The dyadic context of romantic relationships affords great opportunity for theoretical development and integration of self-determination theory with current theories of interdependence and relational well-being.

Global economic prospects and the developing countries, 1995

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1995-12-01

The report`s central message is that the increasing integration of developing countries into the global economy constitutes perhaps the most important opportunity for raising the welfare of both developing and industrial countries over the long term. But the process of integration will not be without frictions that give rise to protectionist pressures. And, as recent events in Mexico have shown, it will increase the complexity of economic management for developing country policymakers. Globalization comes with liberalization, deregulation, and more mobile and potentially volatile cross-border capital flows, which means that sound macroeconomic management commands an increasingly high premium. Penalties for policymore » errors rise. Globalization thus requires closer monitoring and quicker policy responses at the country, regional, and global levels.« less

New opportunities of real-world data from clinical routine settings in life-cycle management of drugs: example of an integrative approach in multiple sclerosis.

PubMed

Rothenbacher, Dietrich; Capkun, Gorana; Uenal, Hatice; Tumani, Hayrettin; Geissbühler, Yvonne; Tilson, Hugh

2015-05-01

The assessment and demonstration of a positive benefit-risk balance of a drug is a life-long process and includes specific data from preclinical, clinical development and post-launch experience. However, new integrative approaches are needed to enrich evidence from clinical trials and sponsor-initiated observational studies with information from multiple additional sources, including registry information and other existing observational data and, more recently, health-related administrative claims and medical records databases. To illustrate the value of this approach, this paper exemplifies such a cross-package approach to the area of multiple sclerosis, exploring also possible analytic strategies when using these multiple sources of information.

Cybermaterials: materials by design and accelerated insertion of materials

NASA Astrophysics Data System (ADS)

Xiong, Wei; Olson, Gregory B.

2016-02-01

Cybermaterials innovation entails an integration of Materials by Design and accelerated insertion of materials (AIM), which transfers studio ideation into industrial manufacturing. By assembling a hierarchical architecture of integrated computational materials design (ICMD) based on materials genomic fundamental databases, the ICMD mechanistic design models accelerate innovation. We here review progress in the development of linkage models of the process-structure-property-performance paradigm, as well as related design accelerating tools. Extending the materials development capability based on phase-level structural control requires more fundamental investment at the level of the Materials Genome, with focus on improving applicable parametric design models and constructing high-quality databases. Future opportunities in materials genomic research serving both Materials by Design and AIM are addressed.

Hand therapy and ergonomics: integration of approaches in vocational rehabilitation and promotion of decent work in Brazil.

PubMed

Tosetto, Thaís; Orsi, Flávia Giuntini

2012-01-01

Among the indicators of Decent Work in Brazil, the one referring to the "Safe Working Environment" was the only which had no improvement in the time series analyzed by the International Labor Organisation. There is an increased number of accidents with significant economic and social impacts. Given that many of these accidents involve the hands and cause functional sequels, this paper presents an integration between the approaches of Hand Therapy and Ergonomics in order to facilitate the process of rehabilitation and reintegration, as well as acting to prevent further accidents, thus contributing to the promotion of Decent Work in the country, particularly with regard to safety and health at work and equal opportunities.

Materials, Structures and Manufacturing: An Integrated Approach to Develop Expandable Structures

NASA Technical Reports Server (NTRS)

Belvin, W. Keith; Zander, Martin E.; Sleight, Daid W.; Connell, John; Holloway, Nancy; Palmieri, Frank

2012-01-01

Membrane dominated space structures are lightweight and package efficiently for launch; however, they must be expanded (deployed) in-orbit to achieve the desired geometry. These expandable structural systems include solar sails, solar power arrays, antennas, and numerous other large aperture devices that are used to collect, reflect and/or transmit electromagnetic radiation. In this work, an integrated approach to development of thin-film damage tolerant membranes is explored using advanced manufacturing. Bio-inspired hierarchical structures were printed on films using additive manufacturing to achieve improved tear resistance and to facilitate membrane deployment. High precision, robust expandable structures can be realized using materials that are both space durable and processable using additive manufacturing. Test results show this initial work produced higher tear resistance than neat film of equivalent mass. Future research and development opportunities for expandable structural systems designed using an integrated approach to structural design, manufacturing, and materials selection are discussed.

Demonstrating the Value of Near Real-time Satellite-based Earth Observations in a Research and Education Framework

NASA Astrophysics Data System (ADS)

Chiu, L.; Hao, X.; Kinter, J. L.; Stearn, G.; Aliani, M.

2017-12-01

The launch of GOES-16 series provides an opportunity to advance near real-time applications in natural hazard detection, monitoring and warning. This study demonstrates the capability and values of receiving real-time satellite-based Earth observations over a fast terrestrial networks and processing high-resolution remote sensing data in a university environment. The demonstration system includes 4 components: 1) Near real-time data receiving and processing; 2) data analysis and visualization; 3) event detection and monitoring; and 4) information dissemination. Various tools are developed and integrated to receive and process GRB data in near real-time, produce images and value-added data products, and detect and monitor extreme weather events such as hurricane, fire, flooding, fog, lightning, etc. A web-based application system is developed to disseminate near-real satellite images and data products. The images are generated with GIS-compatible format (GeoTIFF) to enable convenient use and integration in various GIS platforms. This study enhances the capacities for undergraduate and graduate education in Earth system and climate sciences, and related applications to understand the basic principles and technology in real-time applications with remote sensing measurements. It also provides an integrated platform for near real-time monitoring of extreme weather events, which are helpful for various user communities.

Applied Geophysics Opportunities in the Petroleum Industry

NASA Astrophysics Data System (ADS)

Olgaard, D. L.; Tikku, A.; Roberts, J. C.; Martinez, A.

2012-12-01

Meeting the increasing global demand for energy over the next several decades presents daunting challenges to engineers and scientists, including geoscientists of all disciplines. Many opportunities exist for geophysicists to find and produce oil and gas in a safe, environmentally responsible and affordable manner. Successful oil and gas exploration involves a 'Plates to Pores' approach that integrates multi-scale data from satellites, marine and land seismic and non-seismic field surveys, lab experiments, and even electron microscopy. The petroleum industry is at the forefront of using high performance computing to develop innovative methods to process and analyze large volumes of seismic data and perform realistic numerical modeling, such as finite element fluid flow and rock deformation simulations. Challenging and rewarding jobs in exploration, production and research exist for students with BS/BA, MS and PhD degrees. Geophysics students interested in careers in the petroleum industry should have a broad foundation in science, math and fundamental geosciences at the BS/BA level, as well as mastery of the scientific method, usually gained through thesis work at MS and PhD levels. Field geology or geophysics experience is also valuable. Other personal attributes typical for geoscientists to be successful in industry include a passion for solving complex geoscience problems, the flexibility to work on a variety of assignments throughout a career and skills such as teamwork, communication, integration and leadership. In this presentation we will give examples of research, exploration and production opportunities for geophysicists in petroleum companies and compare and contrast careers in academia vs. industry.

Understanding the school outcomes of juvenile offenders: an exploration of neighborhood influences and motivational resources.

PubMed

Chung, He Len; Mulvey, Edward P; Steinberg, Laurence

2011-08-01

As a group, delinquent youth complete less education and show poor academic outcomes compared to their non-delinquent peers. To better understand pathways to school success, this study integrated individual- and neighborhood-level data to examine academic functioning among 833 White, Black, and Hispanic male juvenile offenders (age 14-17) living in two urban communities. A multilevel path analysis confirmed that youth in relatively more affluent communities report greater access to opportunities in the areas of education and employment, and that these opportunities are associated with higher expectations to succeed and better grades. Findings highlight the importance of taking an ecological approach for understanding processes that shape school effort and achievement. Implications are discussed in the context of promoting academic success among juvenile offenders, specifically, and for understanding pathways to healthy adjustment, more generally.

Integration of health into urban spatial planning through impact assessment: Identifying governance and policy barriers and facilitators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Carmichael, Laurence, E-mail: Laurence.carmichael@uwe.ac.uk; Barton, Hugh; Gray, Selena

This article presents the results of a review of literature examining the barriers and facilitators in integrating health in spatial planning at the local, mainly urban level, through appraisals. Our literature review covered the UK and non UK experiences of appraisals used to consider health issues in the planning process. We were able to identify four main categories of obstacles and facilitators including first the different knowledge and conceptual understanding of health by different actors/stakeholders, second the types of governance arrangements, in particular partnerships, in place and the political context, third the way institutions work, the responsibilities they have andmore » their capacity and resources and fourth the timeliness, comprehensiveness and inclusiveness of the appraisal process. The findings allowed us to draw some lessons on the governance and policy framework regarding the integration of health impact into spatial planning, in particular considering the pros and cons of integrating health impact assessment (HIA) into other forms of impact assessment of spatial planning decisions such as environmental impact assessment (EIA) and strategic environment assessment (SEA). In addition, the research uncovered a gap in the literature that tends to focus on the mainly voluntary HIA to assess health outcomes of planning decisions and neglect the analysis of regulatory mechanisms such as EIA and SEA. - Highlights: Black-Right-Pointing-Pointer Governance and policy barriers and facilitators to the integration of health into urban planning. Black-Right-Pointing-Pointer Review of literature on impact assessment methods used across the world. Black-Right-Pointing-Pointer Knowledge, partnerships, management/resources and processes can impede integration. Black-Right-Pointing-Pointer HIA evaluations prevail uncovering research opportunities for evaluating other techniques.« less

Parent Management Training-Oregon Model (PMTO™) in Mexico City: Integrating Cultural Adaptation Activities in an Implementation Model

PubMed Central

Baumann, Ana A.; Domenech Rodríguez, Melanie M.; Amador, Nancy G.; Forgatch, Marion S.; Parra-Cardona, J. Rubén

2015-01-01

This article describes the process of cultural adaptation at the start of the implementation of the Parent Management Training intervention-Oregon model (PMTO) in Mexico City. The implementation process was guided by the model, and the cultural adaptation of PMTO was theoretically guided by the cultural adaptation process (CAP) model. During the process of the adaptation, we uncovered the potential for the CAP to be embedded in the implementation process, taking into account broader training and economic challenges and opportunities. We discuss how cultural adaptation and implementation processes are inextricably linked and iterative and how maintaining a collaborative relationship with the treatment developer has guided our work and has helped expand our research efforts, and how building human capital to implement PMTO in Mexico supported the implementation efforts of PMTO in other places in the United States. PMID:26052184

Parent Management Training-Oregon Model (PMTO™) in Mexico City: Integrating Cultural Adaptation Activities in an Implementation Model.

PubMed

Baumann, Ana A; Domenech Rodríguez, Melanie M; Amador, Nancy G; Forgatch, Marion S; Parra-Cardona, J Rubén

2014-03-01

This article describes the process of cultural adaptation at the start of the implementation of the Parent Management Training intervention-Oregon model (PMTO) in Mexico City. The implementation process was guided by the model, and the cultural adaptation of PMTO was theoretically guided by the cultural adaptation process (CAP) model. During the process of the adaptation, we uncovered the potential for the CAP to be embedded in the implementation process, taking into account broader training and economic challenges and opportunities. We discuss how cultural adaptation and implementation processes are inextricably linked and iterative and how maintaining a collaborative relationship with the treatment developer has guided our work and has helped expand our research efforts, and how building human capital to implement PMTO in Mexico supported the implementation efforts of PMTO in other places in the United States.

Demonstration of pharmaceutical tablet coating process by injection molding technology.

PubMed

Puri, Vibha; Brancazio, David; Harinath, Eranda; Martinez, Alexander R; Desai, Parind M; Jensen, Keith D; Chun, Jung-Hoon; Braatz, Richard D; Myerson, Allan S; Trout, Bernhardt L

2018-01-15

We demonstrate the coating of tablets using an injection molding (IM) process that has advantage of being solvent free and can provide precision coat features. The selected core tablets comprising 10% w/w griseofulvin were prepared by an integrated hot melt extrusion-injection molding (HME-IM) process. Coating trials were conducted on a vertical injection mold machine. Polyethylene glycol and polyethylene oxide based hot melt extruded coat compositions were used. Tablet coating process feasibility was successfully demonstrated using different coating mold designs (with both overlapping and non-overlapping coatings at the weld) and coat thicknesses of 150 and 300 μm. The resultant coated tablets had acceptable appearance, seal at the weld, and immediate drug release profile (with an acceptable lag time). Since IM is a continuous process, this study opens opportunities to develop HME-IM continuous processes for transforming powder to coated tablets. Copyright © 2017 Elsevier B.V. All rights reserved.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Farren Hunt

Idaho National Laboratory (INL) performed an Annual Effectiveness Review of the Integrated Safety Management System (ISMS), per 48 Code of Federal Regulations (CFR) 970.5223 1, “Integration of Environment, Safety and Health into Work Planning and Execution.” The annual review assessed Integrated Safety Management (ISM) effectiveness, provided feedback to maintain system integrity, and identified target areas for focused improvements and assessments for fiscal year (FY) 2013. Results of the FY 2012 annual effectiveness review demonstrated that the INL’s ISMS program was significantly strengthened. Actions implemented by the INL demonstrate that the overall Integrated Safety Management System is sound and ensures safemore » and successful performance of work while protecting workers, the public, and environment. This report also provides several opportunities for improvement that will help further strengthen the ISM Program and the pursuit of safety excellence. Demonstrated leadership and commitment, continued surveillance, and dedicated resources have been instrumental in maturing a sound ISMS program. Based upon interviews with personnel, reviews of assurance activities, and analysis of ISMS process implementation, this effectiveness review concludes that ISM is institutionalized and is “Effective”.« less

Development of a neutron measurement system in unified non-destructive assay for the PRIDE facility

NASA Astrophysics Data System (ADS)

Seo, Hee; Park, Se-Hwan; Won, Byung-Hee; Ahn, Seong-Kyu; Shin, Hee-Sung; Na, Sang-Ho; Song, Dae-Yong; Kim, Ho-Dong; Lee, Seung Kyu

2013-12-01

The Korea Atomic Energy Research Institute (KAERI) has made an effort to develop pyroprocessing technology to resolve an on-going problem in Korea, i.e., the management of spent nuclear fuels. To this end, a test-bed facility for pyroprocessing, called PRIDE (PyRoprocessing Integrated inactive DEmonstration facility), is being constructed at KAERI. The main objective of PRIDE is to evaluate the performance of the unit processes, remote operation, maintenance, and proliferation resistance. In addition, integrating all unit processes into a one-step process is also one of the main goals. PRIDE can also provide a good opportunity to test safeguards instrumentations for a pyroprocessing facility such as nuclear material accounting devices, surveillance systems, radiation monitoring systems, and process monitoring systems. In the present study, a non-destructive assay (NDA) system for the testing of nuclear material accountancy of PRIDE was designed by integrating three different NDA techniques, i.e., neutron, gamma-ray, and mass measurements. The developed neutron detection module consists of 56 3He tubes and 16 AMPTEK A111 signal processing circuits. The amplifiers were matched in terms of the gain and showed good uniformity after a gain-matching procedure (%RSD=0.37%). The axial and the radial efficiency distributions within the cavity were then measured using a 252Cf neutron source and were compared with the MCNPX calculation results. The measured efficiency distributions showed excellent agreement with the calculations, which confirmed the accuracy of the MCNPX model of the system.

Realization of back-side heterogeneous hybrid III-V/Si DBR lasers for silicon photonics

NASA Astrophysics Data System (ADS)

Durel, Jocelyn; Ferrotti, Thomas; Chantre, Alain; Cremer, Sébastien; Harduin, Julie; Bernabé, Stéphane; Kopp, Christophe; Boeuf, Frédéric; Ben Bakir, Badhise; Broquin, Jean-Emmanuel

2016-02-01

In this paper, the simulation, design and fabrication of a back-side coupling (BSC) concept for silicon photonics, which targets heterogeneous hybrid III-V/Si laser integration is presented. Though various demonstrations of a complete SOI integration of passive and active photonic devices have been made, they all feature multi-level planar metal interconnects, and a lack of integrated light sources. This is mainly due to the conflict between the need of planar surfaces for III-V/Si bonding and multiple levels of metallization. The proposed BSC solution to this topographical problem consists in fabricating lasers on the back-side of the Si waveguides using a new process sequence. The devices are based on a hybrid structure composed of an InGaAsP MQW active area and a Si-based DBR cavity. The emitted light wavelength is accordable within a range of 20 nm around 1.31μm thanks to thermal heaters and the laser output is fiber coupled through a Grating Coupler (GC). From a manufacturing point of view, the BSC approach provides not only the advantages of allowing the use of a thin-BOX SOI instead of a thick one; but it also shifts the laser processing steps and their materials unfriendly to CMOS process to the far back-end areas of fabrication lines. Moreover, aside from solving technological integration issues, the BSC concept offers several new design opportunities for active and passive devices (heat sink, Bragg gratings, grating couplers enhanced with integrated metallic mirrors, tapers…). These building boxes are explored here theoretically and experimentally.

Fusing Sensor Paradigms to Acquire Chemical Information: An Integrative Role for Smart Biopolymeric Hydrogels

PubMed Central

Kim, Eunkyoung; Liu, Yi; Ben-Yoav, Hadar; Winkler, Thomas E.; Yan, Kun; Shi, Xiaowen; Shen, Jana; Kelly, Deanna L.; Ghodssi, Reza; Bentley, William E.

2017-01-01

The Information Age transformed our lives but it has had surprisingly little impact on the way chemical information (e.g., from our biological world) is acquired, analyzed and communicated. Sensor systems are poised to change this situation by providing rapid access to chemical information. This access will be enabled by technological advances from various fields: biology enables the synthesis, design and discovery of molecular recognition elements as well as the generation of cell-based signal processors; physics and chemistry are providing nano-components that facilitate the transmission and transduction of signals rich with chemical information; microfabrication is yielding sensors capable of receiving these signals through various modalities; and signal processing analysis enhances the extraction of chemical information. The authors contend that integral to the development of functional sensor systems will be materials that (i) enable the integrative and hierarchical assembly of various sensing components (for chemical recognition and signal transduction) and (ii) facilitate meaningful communication across modalities. It is suggested that stimuli-responsive self-assembling biopolymers can perform such integrative functions, and redox provides modality-spanning communication capabilities. Recent progress toward the development of electrochemical sensors to manage schizophrenia is used to illustrate the opportunities and challenges for enlisting sensors for chemical information processing. PMID:27616350

Implementation of Recommendations from the One System Comparative Evaluation of the Hanford Tank Farms and Waste Treatment Plant Safety Bases

DOE Office of Scientific and Technical Information (OSTI.GOV)

Garrett, Richard L.; Niemi, Belinda J.; Paik, Ingle K.

2013-11-07

A Comparative Evaluation was conducted for One System Integrated Project Team to compare the safety bases for the Hanford Waste Treatment and Immobilization Plant Project (WTP) and Tank Operations Contract (TOC) (i.e., Tank Farms) by an Expert Review Team. The evaluation had an overarching purpose to facilitate effective integration between WTP and TOC safety bases. It was to provide One System management with an objective evaluation of identified differences in safety basis process requirements, guidance, direction, procedures, and products (including safety controls, key safety basis inputs and assumptions, and consequence calculation methodologies) between WTP and TOC. The evaluation identified 25more » recommendations (Opportunities for Integration). The resolution of these recommendations resulted in 16 implementation plans. The completion of these implementation plans will help ensure consistent safety bases for WTP and TOC along with consistent safety basis processes. procedures, and analyses. and should increase the likelihood of a successful startup of the WTP. This early integration will result in long-term cost savings and significant operational improvements. In addition, the implementation plans lead to the development of eight new safety analysis methodologies that can be used at other U.S. Department of Energy (US DOE) complex sites where URS Corporation is involved.« less

Sustainable multistage process for enhanced productivity of bioplastics from waste remediation through aerobic dynamic feeding strategy: Process integration for up-scaling.

PubMed

Amulya, K; Jukuri, Srinivas; Venkata Mohan, S

2015-01-01

Polyhydroxyalkanoates (PHA) production was evaluated in a multistage operation using food waste as a renewable feedstock. The first step involved the production of bio-hydrogen (bio-H2) via acidogenic fermentation. Volatile fatty acid (VFA) rich effluent from bio-H2 reactor was subsequently used for PHA production, which was carried out in two stages, Stage II (culture enrichment) and Stage III (PHA production). PHA-storing microorganisms were enriched in a sequencing batch reactor (SBR), operated at two different cycle lengths (CL-24; CL-12). Higher polymer recovery as well as VFA removal was achieved in CL-12 operation both in Stage II (16.3% dry cell weight (DCW); VFA removal, 84%) and Stage III (23.7% DCW; VFA removal, 88%). The PHA obtained was a co-polymer [P(3HB-co-3HV)] of PHB and PHV. The results obtained indicate that this integrated multistage process offers new opportunities to further leverage large scale PHA production with simultaneous waste remediation in the framework of biorefinery. Copyright © 2015 Elsevier Ltd. All rights reserved.

Scale-up and process integration of sugar production by acidolysis of municipal solid waste/corn stover blends in ionic liquids

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, Chenlin; Liang, Ling; Sun, Ning

The study presents the successful scale-up demonstration of the acid-assisted IL deconstruction on feedstock blends of municipal solid wastes and agricultural residues (corn stover) by 30-fold, relative to the bench scale (6L vs 0.2L), at 10% solid loading. By integrating IL pretreatment and acid hydrolysis with subsequent centrifugation and extraction, the sugar and lignin products can be further recovered efficiently. This scale-up development at Advanced Biofuels/Bioproducts Process Demonstration Unit (ABPDU) will leverage the opportunity and synergistic efforts towards developing a cost-effective IL based deconstruction technology by drastically eliminating enzyme, reducing water usage, and simplifying the downstream sugar/lignin recovery and ILmore » recycling. Results indicate that MSW blends are viable and valuable resource to consider when assessing biomass availability and affordability for lignocellulosic biorefineries. This scale-up evaluation demonstrates that the acid-assisted IL deconstruction technology can be effectively scaled up to larger operations and the current study established the baseline of scaling parameters for this process.« less

Scale-up and process integration of sugar production by acidolysis of municipal solid waste/corn stover blends in ionic liquids

DOE PAGES

Li, Chenlin; Liang, Ling; Sun, Ning; ...

2017-01-05

The study presents the successful scale-up demonstration of the acid-assisted IL deconstruction on feedstock blends of municipal solid wastes and agricultural residues (corn stover) by 30-fold, relative to the bench scale (6L vs 0.2L), at 10% solid loading. By integrating IL pretreatment and acid hydrolysis with subsequent centrifugation and extraction, the sugar and lignin products can be further recovered efficiently. This scale-up development at Advanced Biofuels/Bioproducts Process Demonstration Unit (ABPDU) will leverage the opportunity and synergistic efforts towards developing a cost-effective IL based deconstruction technology by drastically eliminating enzyme, reducing water usage, and simplifying the downstream sugar/lignin recovery and ILmore » recycling. Results indicate that MSW blends are viable and valuable resource to consider when assessing biomass availability and affordability for lignocellulosic biorefineries. This scale-up evaluation demonstrates that the acid-assisted IL deconstruction technology can be effectively scaled up to larger operations and the current study established the baseline of scaling parameters for this process.« less

Using the Integrated Vehicle Health Management Research Test and Integration Plan Wiki to Identify Synergistic Test Opportunities

NASA Technical Reports Server (NTRS)

Koelfgen, Syri J.; Faber, James J.

2010-01-01

The National Aeronautics and Space Administration (NASA) and the aviation industry have recognized a need for developing a method to identify and combine resources to carry out research and testing more efficiently. The Integrated Vehicle Health Management (IVHM) Research Test and Integration Plan (RTIP) Wiki is a tool that is used to visualize, plan, and accomplish collaborative research and testing. Synergistic test opportunities are developed using the RTIP Wiki, and include potential common resource testing that combines assets and personnel from NASA, industry, academia, and other government agencies. A research scenario is linked to the appropriate IVHM milestones and resources detailed in the wiki, reviewed by the research team members, and integrated into a collaborative test strategy. The scenario is then implemented by creating a test plan when appropriate and the research is performed. The benefits of performing collaborative research and testing are achieving higher Technology Readiness Level (TRL) test opportunities with little or no additional cost, improved quality of research, and increased communication among researchers. In addition to a description of the method of creating these joint research scenarios, examples of the successful development and implementation of cooperative research using the IVHM RTIP Wiki are given.

Evidence and opportunities for integrating landscape ecology into natural resource planning across multiple-use landscapes

USGS Publications Warehouse

Trammel, E. Jamie; Carter, Sarah; Haby, Travis S.; Taylor, Jason J.

2018-01-01

Enhancing natural resource management has been a focus of landscape ecology since its inception, but numerous authors argue that landscape ecology has not yet been effective in achieving the underlying goal of planning and designing sustainable landscapes. We developed nine questions reflecting the application of fundamental research topics in landscape ecology to the landscape planning process and reviewed two recent landscape-scale plans in western North America for evidence of these concepts in plan decisions. Both plans considered multiple resources, uses, and values, including energy development, recreation, conservation, and protection of cultural and historic resources. We found that land use change and multiscale perspectives of resource uses and values were very often apparent in planning decisions. Pattern-process relationships, connectivity and fragmentation, ecosystem services, landscape history, and climate change were reflected less frequently. Landscape sustainability was considered only once in the 295 decisions reviewed, and outputs of landscape models were not referenced. We suggest six actionable opportunities for further integrating landscape ecology concepts into landscape planning efforts: 1) use landscape sustainability as an overarching goal, 2) adopt a broad ecosystem services framework, 3) explore the role of landscape history more comprehensively, 4) regularly consider and accommodate potential effects of climate change, 5) use landscape models to support plan decisions, and 6) promote a greater presence of landscape ecologists within agencies that manage large land bases and encourage active involvement in agency planning efforts. Together these actions may improve the defensibility, durability, and sustainability of landscape plan decisions.

Integration of microalgae cultivation with industrial waste remediation for biofuel and bioenergy production: opportunities and limitations.

PubMed

McGinn, Patrick J; Dickinson, Kathryn E; Bhatti, Shabana; Frigon, Jean-Claude; Guiot, Serge R; O'Leary, Stephen J B

2011-09-01

There is currently a renewed interest in developing microalgae as a source of renewable energy and fuel. Microalgae hold great potential as a source of biomass for the production of energy and fungible liquid transportation fuels. However, the technologies required for large-scale cultivation, processing, and conversion of microalgal biomass to energy products are underdeveloped. Microalgae offer several advantages over traditional 'first-generation' biofuels crops like corn: these include superior biomass productivity, the ability to grow on poor-quality land unsuitable for agriculture, and the potential for sustainable growth by extracting macro- and micronutrients from wastewater and industrial flue-stack emissions. Integrating microalgal cultivation with municipal wastewater treatment and industrial CO(2) emissions from coal-fired power plants is a potential strategy to produce large quantities of biomass, and represents an opportunity to develop, test, and optimize the necessary technologies to make microalgal biofuels more cost-effective and efficient. However, many constraints on the eventual deployment of this technology must be taken into consideration and mitigating strategies developed before large scale microalgal cultivation can become a reality. As a strategy for CO(2) biomitigation from industrial point source emitters, microalgal cultivation can be limited by the availability of land, light, and other nutrients like N and P. Effective removal of N and P from municipal wastewater is limited by the processing capacity of available microalgal cultivation systems. Strategies to mitigate against the constraints are discussed.

Secondary Payload Opportunities on NASA's Space Launch System (SLS) Enable Science and Deep Space Exploration

NASA Technical Reports Server (NTRS)

Singer, Jody; Pelfrey, Joseph; Norris, George

2016-01-01

For the first time in almost 40 years, a NASA human-rated launch vehicle has completed its Critical Design Review (CDR). With this milestone, NASA's Space Launch System (SLS) and Orion spacecraft are on the path to launch a new era of deep space exploration. This first launch of SLS and the Orion Spacecraft is planned no later than November 2018 and will fly along a trans-lunar trajectory, testing the performance of the SLS and Orion systems for future missions. NASA is making investments to expand the science and exploration capability of the SLS by developing the capability to deploy small satellites during the trans-lunar phase of the mission trajectory. Exploration Mission 1 (EM-1) will include thirteen 6U Cubesat small satellites to be deployed beyond low earth orbit. By providing an earth-escape trajectory, opportunities are created for the advancement of small satellite subsystems, including deep space communications and in-space propulsion. This SLS capability also creates low-cost options for addressing existing Agency strategic knowledge gaps and affordable science missions. A new approach to payload integration and mission assurance is needed to ensure safety of the vehicle, while also maintaining reasonable costs for the small payload developer teams. SLS EM-1 will provide the framework and serve as a test flight, not only for vehicle systems, but also payload accommodations, ground processing, and on-orbit operations. Through developing the requirements and integration processes for EM-1, NASA is outlining the framework for the evolved configuration of secondary payloads on SLS Block upgrades. The lessons learned from the EM-1 mission will be applied to processes and products developed for future block upgrades. In the heavy-lift configuration of SLS, payload accommodations will increase for secondary opportunities including small satellites larger than the traditional Cubesat class payload. The payload mission concept of operations, proposed payload capacity of SLS, and the payload requirements for launch and deployment will be described to provide potential payload users an understanding of this unique exploration capability.

An Evaluation of the Effect of D.C.'s Voucher Program on Public School Achievement and Racial Integration after One Year. Education Working Paper No. 10.

ERIC Educational Resources Information Center

Greene, Jay P.; Winters, Marcus A.

2006-01-01

This study evaluates the initial effect of Washington, D.C.'s Opportunity Scholarship Program (OSP) on the academic performance of public schools and its effects on the opportunities that District students have to attend integrated schools. The OSP is a federally sponsored school voucher program that provides vouchers worth up to $7,500 for an…

A Collaborative Problem-solving Process Through Environmental Field Studies

NASA Astrophysics Data System (ADS)

Kim, Mijung; Teck Tan, Hoe

2013-02-01

This study explored and documented students' responses to opportunities for collective knowledge building and collaboration in a problem-solving process within complex environmental challenges and pressing issues with various dimensions of knowledge and skills. Middle-school students (n = 16; age 14) and high-school students (n = 16; age 17) from two Singapore public institutions participated in an environmental science field study to experience knowledge integration and a decision-making process. Students worked on six research topics to understand the characteristics of an organic farm and plan for building an ecological village. Students collected and analysed data from the field and shared their findings. Their field work and discussions were video-recorded, and their reflective notes and final reports were collected for data coding and interpretation. The results revealed that throughout the study, students experienced the needs and development of integrated knowledge, encountered the challenges of knowledge sharing and communication during their collaboration, and learned how to cope with the difficulties. Based on research findings, this study further discusses students' learning through a collaborative problem-solving process, including the interdependence of knowledge and the development of mutual relationships such as respect and care for others' knowledge and learning.

Integrating Climate Change Adaptation into Disaster Risk Reduction in Urban Contexts: Perceptions and Practice

PubMed Central

Rivera, Claudia

2014-01-01

This paper analyses the perceptions of disaster risk reduction (DRR) practitioners concerning the on-going integration of climate change adaptation (CCA) into their practices in urban contexts in Nicaragua. Understanding their perceptions is important as this will provide information on how this integration can be improved. Exploring the perceptions of practitioners in Nicaragua is important as the country has a long history of disasters, and practitioners have been developing the current DRR planning framework for more than a decade. The analysis is based on semi-structured interviews designed to collect information about practitioners’ understanding of: (a) CCA, (b) the current level of integration of CCA into DRR and urban planning, (c) the opportunities and constraints of this integration, and (d) the potential to adapt cities to climate change. The results revealed that practitioners’ perception is that the integration of CCA into their practice is at an early stage, and that they need to improve their understanding of CCA in terms of a development issue. Three main constraints on improved integration were identified: (a) a recognized lack of understanding of CCA, (b) insufficient guidance on how to integrate it, and (c) the limited opportunities to integrate it into urban planning due to a lack of instruments and capacity in this field. Three opportunities were also identified: (a) practitioners’ awareness of the need to integrate CCA into their practices, (b) the robust structure of the DRR planning framework in the country, which provides a suitable channel for facilitating integration, and (c) the fact that CCA is receiving more attention and financial and technical support from the international community. PMID:24475365

Trait-based approaches for understanding microbial biodiversity and ecosystem functioning

PubMed Central

Krause, Sascha; Le Roux, Xavier; Niklaus, Pascal A.; Van Bodegom, Peter M.; Lennon, Jay T.; Bertilsson, Stefan; Grossart, Hans-Peter; Philippot, Laurent; Bodelier, Paul L. E.

2014-01-01

In ecology, biodiversity-ecosystem functioning (BEF) research has seen a shift in perspective from taxonomy to function in the last two decades, with successful application of trait-based approaches. This shift offers opportunities for a deeper mechanistic understanding of the role of biodiversity in maintaining multiple ecosystem processes and services. In this paper, we highlight studies that have focused on BEF of microbial communities with an emphasis on integrating trait-based approaches to microbial ecology. In doing so, we explore some of the inherent challenges and opportunities of understanding BEF using microbial systems. For example, microbial biologists characterize communities using gene phylogenies that are often unable to resolve functional traits. Additionally, experimental designs of existing microbial BEF studies are often inadequate to unravel BEF relationships. We argue that combining eco-physiological studies with contemporary molecular tools in a trait-based framework can reinforce our ability to link microbial diversity to ecosystem processes. We conclude that such trait-based approaches are a promising framework to increase the understanding of microbial BEF relationships and thus generating systematic principles in microbial ecology and more generally ecology. PMID:24904563

Mission Possible: BioMedical Experiments on the Space Shuttle

NASA Technical Reports Server (NTRS)

Bopp, E.; Kreutzberg, K.

2011-01-01

Biomedical research, both applied and basic, was conducted on every Shuttle mission from 1981 to 2011. The Space Shuttle Program enabled NASA investigators and researchers from around the world to address fundamental issues concerning living and working effectively in space. Operationally focused occupational health investigations and tests were given priority by the Shuttle crew and Shuttle Program management for the resolution of acute health issues caused by the rigors of spaceflight. The challenges of research on the Shuttle included: limited up and return mass, limited power, limited crew time, and requirements for containment of hazards. The sheer capacity of the Shuttle for crew and equipment was unsurpassed by any other launch and entry vehicle and the Shuttle Program provided more opportunity for human research than any program before or since. To take advantage of this opportunity, life sciences research programs learned how to: streamline the complicated process of integrating experiments aboard the Shuttle, design experiments and hardware within operational constraints, and integrate requirements between different experiments and with operational countermeasures. We learned how to take advantage of commercial-off-the-shelf hardware and developed a hardware certification process with the flexibility to allow for design changes between flights. We learned the importance of end-to-end testing for experiment hardware with humans-in-the-loop. Most importantly, we learned that the Shuttle Program provided an excellent platform for conducting human research and for developing the systems that are now used to optimize research on the International Space Station. This presentation will include a review of the types of experiments and medical tests flown on the Shuttle and the processes that were used to manifest and conduct the experiments. Learning Objective: This paper provides a description of the challenges related to launching and implementing biomedical experiments aboard the Space Shuttle.

The sky is the limit: reconstructing physical geography fieldwork from an aerial perspective

NASA Astrophysics Data System (ADS)

Williams, R.; Tooth, S.; Gibson, M.; Barrett, B.

2017-12-01

In an era of rapid geographical data acquisition, interpretations of remote sensing products (e.g. aerial photographs, satellite images, digital elevation models) are an integral part of many undergraduate geography degree schemes but there are fewer opportunities for collection and processing of primary remote sensing data. Unmanned aerial vehicles (UAVs) provide a relatively cheap opportunity to introduce the principles and practice of airborne remote sensing into fieldcourses, enabling students to learn about image acquisition, data processing and interpretation of derived products. Three case studies illustrate how a low cost DJI Phantom UAV can be used by students to acquire images that can be processed using off the shelf Structure-from-Motion photogrammetry software. Two case studies are drawn from an international fieldcourse that takes students to field sites that are the focus of current funded research whilst a third case study is from a course in topographic mapping. Results from a student questionnaire and analysis of assessed student reports showed that using UAVs in fieldwork enhanced student engagement with themes on their fieldcourse and equipped them with data processing skills. The derivation of bespoke orthophotos and Digital Elevation Models also provided students with opportunities to gain insight into the various data quality issues that are associated with aerial imagery acquisition and topographic reconstruction, although additional training is required to maximise this potential. Recognition of the successes and limitations of this teaching intervention provides scope for improving exercises that use UAVs and other technologies in future fieldcourses. UAVs are enabling both a reconstruction of how we measure the Earth's surface and a reconstruction of how students do fieldwork.

Search predicts and changes patience in intertemporal choice

PubMed Central

Johnson, Eric J.

2017-01-01

Intertemporal choice impacts many important outcomes, such as decisions about health, education, wealth, and the environment. However, the psychological processes underlying decisions involving outcomes at different points in time remain unclear, limiting opportunities to intervene and improve people’s patience. This research examines information-search strategies used during intertemporal choice and their impact on decisions. In experiment 1, we demonstrate that search strategies vary substantially across individuals. We subsequently identify two distinct search strategies across individuals. Comparative searchers, who compare features across options, discount future options less and are more susceptible to acceleration versus delay framing than integrative searchers, who integrate the features of an option. Experiment 2 manipulates search using an unobtrusive method to establish a causal relationship between strategy and choice, randomly assigning participants to conditions promoting either comparative or integrative search. Again, comparative search promotes greater patience than integrative search. Additionally, when participants adopt a comparative search strategy, they also exhibit greater effects of acceleration versus delay framing. Although most participants reported that the manipulation did not change their behavior, promoting comparative search decreased discounting of future rewards substantially and speeded patient choices. These findings highlight the central role that heterogeneity in psychological processes plays in shaping intertemporal choice. Importantly, these results indicate that theories that ignore variability in search strategies may be inadvertently aggregating over different subpopulations that use very different processes. The findings also inform interventions in choice architecture to increase patience and improve consumer welfare. PMID:29078303

Shared Decision-Making for Nursing Practice: An Integrative Review.

PubMed

Truglio-Londrigan, Marie; Slyer, Jason T

2018-01-01

Shared decision-making has received national and international interest by providers, educators, researchers, and policy makers. The literature on shared decision-making is extensive, dealing with the individual components of shared decision-making rather than a comprehensive process. This view of shared decision-making leaves healthcare providers to wonder how to integrate shared decision-making into practice. To understand shared decision-making as a comprehensive process from the perspective of the patient and provider in all healthcare settings. An integrative review was conducted applying a systematic approach involving a literature search, data evaluation, and data analysis. The search included articles from PubMed, CINAHL, the Cochrane Central Register of Controlled Trials, and PsycINFO from 1970 through 2016. Articles included quantitative experimental and non-experimental designs, qualitative, and theoretical articles about shared decision-making between all healthcare providers and patients in all healthcare settings. Fifty-two papers were included in this integrative review. Three categories emerged from the synthesis: (a) communication/ relationship building; (b) working towards a shared decision; and (c) action for shared decision-making. Each major theme contained sub-themes represented in the proposed visual representation for shared decision-making. A comprehensive understanding of shared decision-making between the nurse and the patient was identified. A visual representation offers a guide that depicts shared decision-making as a process taking place during a healthcare encounter with implications for the continuation of shared decisions over time offering patients an opportunity to return to the nurse for reconsiderations of past shared decisions.

Search predicts and changes patience in intertemporal choice.

PubMed

Reeck, Crystal; Wall, Daniel; Johnson, Eric J

2017-11-07

Intertemporal choice impacts many important outcomes, such as decisions about health, education, wealth, and the environment. However, the psychological processes underlying decisions involving outcomes at different points in time remain unclear, limiting opportunities to intervene and improve people's patience. This research examines information-search strategies used during intertemporal choice and their impact on decisions. In experiment 1, we demonstrate that search strategies vary substantially across individuals. We subsequently identify two distinct search strategies across individuals. Comparative searchers, who compare features across options, discount future options less and are more susceptible to acceleration versus delay framing than integrative searchers, who integrate the features of an option. Experiment 2 manipulates search using an unobtrusive method to establish a causal relationship between strategy and choice, randomly assigning participants to conditions promoting either comparative or integrative search. Again, comparative search promotes greater patience than integrative search. Additionally, when participants adopt a comparative search strategy, they also exhibit greater effects of acceleration versus delay framing. Although most participants reported that the manipulation did not change their behavior, promoting comparative search decreased discounting of future rewards substantially and speeded patient choices. These findings highlight the central role that heterogeneity in psychological processes plays in shaping intertemporal choice. Importantly, these results indicate that theories that ignore variability in search strategies may be inadvertently aggregating over different subpopulations that use very different processes. The findings also inform interventions in choice architecture to increase patience and improve consumer welfare. Copyright © 2017 the Author(s). Published by PNAS.

Mechanically flexible optically transparent silicon fabric with high thermal budget devices from bulk silicon (100)

NASA Astrophysics Data System (ADS)

Hussain, Muhammad M.; Rojas, Jhonathan P.; Torres Sevilla, Galo A.

2013-05-01

Today's information age is driven by silicon based electronics. For nearly four decades semiconductor industry has perfected the fabrication process of continuingly scaled transistor - heart of modern day electronics. In future, silicon industry will be more pervasive, whose application will range from ultra-mobile computation to bio-integrated medical electronics. Emergence of flexible electronics opens up interesting opportunities to expand the horizon of electronics industry. However, silicon - industry's darling material is rigid and brittle. Therefore, we report a generic batch fabrication process to convert nearly any silicon electronics into a flexible one without compromising its (i) performance; (ii) ultra-large-scale-integration complexity to integrate billions of transistors within small areas; (iii) state-of-the-art process compatibility, (iv) advanced materials used in modern semiconductor technology; (v) the most widely used and well-studied low-cost substrate mono-crystalline bulk silicon (100). In our process, we make trenches using anisotropic reactive ion etching (RIE) in the inactive areas (in between the devices) of a silicon substrate (after the devices have been fabricated following the regular CMOS process), followed by a dielectric based spacer formation to protect the sidewall of the trench and then performing an isotropic etch to create caves in silicon. When these caves meet with each other the top portion of the silicon with the devices is ready to be peeled off from the bottom silicon substrate. Release process does not need to use any external support. Released silicon fabric (25 μm thick) is mechanically flexible (5 mm bending radius) and the trenches make it semi-transparent (transparency of 7%).

Multi-View Interaction Modelling of human collaboration processes: a business process study of head and neck cancer care in a Dutch academic hospital.

PubMed

Stuit, Marco; Wortmann, Hans; Szirbik, Nick; Roodenburg, Jan

2011-12-01

In the healthcare domain, human collaboration processes (HCPs), which consist of interactions between healthcare workers from different (para)medical disciplines and departments, are of growing importance as healthcare delivery becomes increasingly integrated. Existing workflow-based process modelling tools for healthcare process management, which are the most commonly applied, are not suited for healthcare HCPs mainly due to their focus on the definition of task sequences instead of the graphical description of human interactions. This paper uses a case study of a healthcare HCP at a Dutch academic hospital to evaluate a novel interaction-centric process modelling method. The HCP under study is the care pathway performed by the head and neck oncology team. The evaluation results show that the method brings innovative, effective, and useful features. First, it collects and formalizes the tacit domain knowledge of the interviewed healthcare workers in individual interaction diagrams. Second, the method automatically integrates these local diagrams into a single global interaction diagram that reflects the consolidated domain knowledge. Third, the case study illustrates how the method utilizes a graphical modelling language for effective tree-based description of interactions, their composition and routing relations, and their roles. A process analysis of the global interaction diagram is shown to identify HCP improvement opportunities. The proposed interaction-centric method has wider applicability since interactions are the core of most multidisciplinary patient-care processes. A discussion argues that, although (multidisciplinary) collaboration is in many cases not optimal in the healthcare domain, it is increasingly considered a necessity to improve integration, continuity, and quality of care. The proposed method is helpful to describe, analyze, and improve the functioning of healthcare collaboration. Copyright © 2011 Elsevier Inc. All rights reserved.

Using system dynamics for collaborative design: a case study

PubMed Central

Elf, Marie; Putilova, Mariya; von Koch, Lena; Öhrn, Kerstin

2007-01-01

Background In order to facilitate the collaborative design, system dynamics (SD) with a group modelling approach was used in the early stages of planning a new stroke unit. During six workshops a SD model was created in a multiprofessional group. Aim To explore to which extent and how the use of system dynamics contributed to the collaborative design process. Method A case study was conducted using several data sources. Results SD supported a collaborative design, by facilitating an explicit description of stroke care process, a dialogue and a joint understanding. The construction of the model obliged the group to conceptualise the stroke care and experimentation with the model gave the opportunity to reflect on care. Conclusion SD facilitated the collaborative design process and should be integrated in the early stages of the design process as a quality improvement tool. PMID:17683519

Freeze-Casting of Porous Biomaterials: Structure, Properties and Opportunities

PubMed Central

Deville, Sylvain

2010-01-01

The freeze-casting of porous materials has received a great deal of attention during the past few years. This simple process, where a material suspension is simply frozen and then sublimated, provides materials with unique porous architectures, where the porosity is almost a direct replica of the frozen solvent crystals. This review focuses on the recent results on the process and the derived porous structures with regards to the biomaterials applications. Of particular interest is the architecture of the materials and the versatility of the process, which can be readily controlled and applied to biomaterials applications. A careful control of the starting formulation and processing conditions is required to control the integrity of the structure and resulting properties. Further in vitro and in vivo investigations are required to validate the potential of this new class of porous materials.

Challenges and Opportunities: One Stop Processing of Automatic Large-Scale Base Map Production Using Airborne LIDAR Data Within GIS Environment. Case Study: Makassar City, Indonesia

NASA Astrophysics Data System (ADS)

Widyaningrum, E.; Gorte, B. G. H.

2017-05-01

LiDAR data acquisition is recognized as one of the fastest solutions to provide basis data for large-scale topographical base maps worldwide. Automatic LiDAR processing is believed one possible scheme to accelerate the large-scale topographic base map provision by the Geospatial Information Agency in Indonesia. As a progressive advanced technology, Geographic Information System (GIS) open possibilities to deal with geospatial data automatic processing and analyses. Considering further needs of spatial data sharing and integration, the one stop processing of LiDAR data in a GIS environment is considered a powerful and efficient approach for the base map provision. The quality of the automated topographic base map is assessed and analysed based on its completeness, correctness, quality, and the confusion matrix.

Hybrid welding of dissimilar metals

NASA Astrophysics Data System (ADS)

Samigullin, A. D.; Bashmakov, D. A.; Israphilov, I. Kh; Turichin, G. A.

2017-01-01

The article addresses issues laser - plasma welding (LPW) dissimilar metals and the results of metallographic studies of the microstructure of welds ferrite - 40 steel and molybdenum - steel 40. Increasing potential opportunities the high-energy processing is carried out by integration the laser radiation (LR) and plasma, which allows you to create the desired spatial distribution of the energy flow for technological processes (TP) of laser-plasma heat treatment (LPT) of metals. The distribution of the thermal field is determined by the density distribution of energy flow LR and plasma exposure time, and the thermal characteristics of the treated metal. The most interesting is the treatment of details with ring flow of plasma and LR axial impact.

New Opportunities for an Ancient Material

PubMed Central

Omenetto, Fiorenzo G.; Kaplan, David L.

2011-01-01

Spiders and silkworms generate silk protein fibers that embody strength and beauty. Orb webs are fascinating feats of bioengineering in nature, displaying magnificent architectures while providing essential survival utility for spiders. The unusual combination of high strength and extensibility is a characteristic unavailable to date in synthetic materials yet is attained in nature with a relatively simple protein processed from water. This biological template suggests new directions to emulate in the pursuit of new high-performance, multifunctional materials generated with a green chemistry and processing approach. These bio-inspired and high-technology materials can lead to multifunctional material platforms that integrate with living systems for medical materials and a host of other applications. PMID:20671180

Technical Challenges and Opportunities of Centralizing Space Science Mission Operations (SSMO) at NASA Goddard Space Flight Center

NASA Technical Reports Server (NTRS)

Ido, Haisam; Burns, Rich

2015-01-01

The NASA Goddard Space Science Mission Operations project (SSMO) is performing a technical cost-benefit analysis for centralizing and consolidating operations of a diverse set of missions into a unified and integrated technical infrastructure. The presentation will focus on the notion of normalizing spacecraft operations processes, workflows, and tools. It will also show the processes of creating a standardized open architecture, creating common security models and implementations, interfaces, services, automations, notifications, alerts, logging, publish, subscribe and middleware capabilities. The presentation will also discuss how to leverage traditional capabilities, along with virtualization, cloud computing services, control groups and containers, and possibly Big Data concepts.

Information systems for the materials management department: stand-alone and enterprise resource planning systems.

PubMed

2005-03-01

Materials management information systems (MMISs) incorporate information tools that hospitals can use to automate certain business processes, increase staff compliance with these processes, and identify opportunities for cost savings. Recently, there has been a push by hospital administration to purchase enterprise resource planning (ERP) systems, information systems that promise to integrate many more facets of healthcare business. We offer this article to help materials managers, administrators, and others involved with information system selection understand the changes that have taken place in materials management information systems, decide whether they need a new system and, if so, whether a stand-alone MMIS or an ERP system will be the best choice.

Development of manufacturing systems for nanocrystalline and ultra-fine grain materials employing indexing equal channel angular pressing

NASA Astrophysics Data System (ADS)

Hester, Michael Wayne

Nanotechnology offers significant opportunities in providing solutions to existing engineering problems as well as breakthroughs in new fields of science and technology. In order to fully realize benefits from such initiatives, nanomanufacturing methods must be developed to integrate enabling constructs into commercial mainstream. Even though significant advances have been made, widespread industrialization in many areas remains limited. Manufacturing methods, therefore, must continually be developed to bridge gaps between nanoscience discovery and commercialization. A promising technology for integration of top-down nanomanufacturing yet to receive full industrialization is equal channel angular pressing, a process transforming metallic materials into nanostructured or ultra-fine grained materials with significantly improved performance characteristics. To bridge the gap between process potential and actual manufacturing output, a prototype top-down nanomanufacturing system identified as indexing equal channel angular pressing (IX-ECAP) was developed. The unit was designed to capitalize on opportunities of transforming spent or scrap engineering elements into key engineering commodities. A manufacturing system was constructed to impose severe plastic deformation via simple shear in an equal channel angular pressing die on 1100 and 4043 aluminum welding rods. 1/4 fraction factorial split-plot experiments assessed significance of five predictors on the response, microhardness, for the 4043 alloy. Predictor variables included temperature, number of passes, pressing speed, back pressure, and vibration. Main effects were studied employing a resolution III design. Multiple linear regression was used for model development. Initial studies were performed using continuous processing followed by contingency designs involving discrete variable length work pieces. IX-ECAP offered a viable solution in severe plastic deformation processing. Discrete variable length work piece pressing proved very successful. With three passes through the system, 4043 processed material experienced an 88.88% increase in microhardness, 203.4% increase in converted yield strength, and a 98.5% reduction in theoretical final grain size to 103 nanometers using the Hall-Petch relation. The process factor, number of passes, was statistically significant at the 95% confidence level; whereas, temperature was significant at the 90% confidence level. Limitations of system components precluded completion of studies involving continuous pressing. Proposed system redesigns, however, will ensure mainstream commercialization of continuous length work piece processing.

Ecosystem functioning is enveloped by hydrometeorological variability.

PubMed

Pappas, Christoforos; Mahecha, Miguel D; Frank, David C; Babst, Flurin; Koutsoyiannis, Demetris

2017-09-01

Terrestrial ecosystem processes, and the associated vegetation carbon dynamics, respond differently to hydrometeorological variability across timescales, and so does our scientific understanding of the underlying mechanisms. Long-term variability of the terrestrial carbon cycle is not yet well constrained and the resulting climate-biosphere feedbacks are highly uncertain. Here we present a comprehensive overview of hydrometeorological and ecosystem variability from hourly to decadal timescales integrating multiple in situ and remote-sensing datasets characterizing extra-tropical forest sites. We find that ecosystem variability at all sites is confined within a hydrometeorological envelope across sites and timescales. Furthermore, ecosystem variability demonstrates long-term persistence, highlighting ecological memory and slow ecosystem recovery rates after disturbances. However, simulation results with state-of-the-art process-based models do not reflect this long-term persistent behaviour in ecosystem functioning. Accordingly, we develop a cross-time-scale stochastic framework that captures hydrometeorological and ecosystem variability. Our analysis offers a perspective for terrestrial ecosystem modelling and paves the way for new model-data integration opportunities in Earth system sciences.

Enterprise SRS: leveraging ongoing operations to advance nuclear fuel cycles research and development programs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Murray, A.M.; Marra, J.E.; Wilmarth, W.R.

2013-07-01

The Savannah River Site (SRS) is re-purposing its vast array of assets (including H Canyon - a nuclear chemical separation plant) to solve issues regarding advanced nuclear fuel cycle technologies, nuclear materials processing, packaging, storage and disposition. The vehicle for this transformation is Enterprise SRS which presents a new, radical view of SRS as a united endeavor for 'all things nuclear' as opposed to a group of distinct and separate entities with individual missions and organizations. Key among the Enterprise SRS strategic initiatives is the integration of research into SRS facilities but also in other facilities in conjunction with on-goingmore » missions to provide researchers from other national laboratories, academic institutions, and commercial entities the opportunity to demonstrate their technologies in a relevant environment and scale prior to deployment. To manage that integration of research demonstrations into site facilities, a center for applied nuclear materials processing and engineering research has been established in SRS.« less

Screening of lipid composition for scalable fabrication of solvent free lipid microarrays

NASA Astrophysics Data System (ADS)

Ghazanfari, Lida; Lenhert, Steven

2016-12-01

Liquid microdroplet arrays on surfaces are a promising approach to the miniaturization of laboratory processes such as high throughput screening. The fluid nature of these droplets poses unique challenges and opportunities in their fabrication and application, particularly for the scalable integration of multiple materials over large areas and immersion into cell culture solution. Here we use pin spotting and nanointaglio printing to screen a library of lipids and their mixtures for their compatibility with these fabrication processes, as well as stability upon immersion into aqueous solution. More than 200 combinations of natural and synthetic oils composed of fatty acids, triglycerides, and hydrocarbons were tested for their pin-spotting and nanointaglio print quality and their ability to contain the fluorescent compound TRITC upon immersion in water. A combination of castor oil and hexanoic acid at the ratio of 1:1 (w/w) was found optimal for producing reproducible patterns that are stable upon immersion into water. This method is capable of large scale nano-materials integration.

A three-dimensional optical photonic crystal with designed point defects

NASA Astrophysics Data System (ADS)

Qi, Minghao; Lidorikis, Elefterios; Rakich, Peter T.; Johnson, Steven G.; Joannopoulos, J. D.; Ippen, Erich P.; Smith, Henry I.

2004-06-01

Photonic crystals offer unprecedented opportunities for miniaturization and integration of optical devices. They also exhibit a variety of new physical phenomena, including suppression or enhancement of spontaneous emission, low-threshold lasing, and quantum information processing. Various techniques for the fabrication of three-dimensional (3D) photonic crystals-such as silicon micromachining, wafer fusion bonding, holographic lithography, self-assembly, angled-etching, micromanipulation, glancing-angle deposition and auto-cloning-have been proposed and demonstrated with different levels of success. However, a critical step towards the fabrication of functional 3D devices, that is, the incorporation of microcavities or waveguides in a controllable way, has not been achieved at optical wavelengths. Here we present the fabrication of 3D photonic crystals that are particularly suited for optical device integration using a lithographic layer-by-layer approach. Point-defect microcavities are introduced during the fabrication process and optical measurements show they have resonant signatures around telecommunications wavelengths (1.3-1.5µm). Measurements of reflectance and transmittance at near-infrared are in good agreement with numerical simulations.

Explosive Welding in the 1990's

NASA Technical Reports Server (NTRS)

Lalwaney, N. S.; Linse, V. D.

1985-01-01

Explosive bonding is a unique joining process with the serious potential to produce composite materials capable of fulfilling many of the high performance materials capable of fulfilling many of the high performance materials needs of the 1990's. The process has the technological versatility to provide a true high quality metallurgical compatible and incompatible systems. Metals routinely explosively bonded include a wide variety of combinations of reactive and refractory metals, low and high density metals and their alloys, corrosion resistant and high strength alloys, and common steels. The major advantage of the process is its ability to custom design and engineer composites with physical and/or mechanical properties that meet a specific or unusual performance requirement. Explosive bonding offers the designer unique opportunities in materials selection with unique combinations of properties and high integrity bonds that cannot be achieved by any other metal joining process. The process and some applications are discussed.

It's Money! Real-World Grant Experience through a Student-Run, Peer-Reviewed Program

PubMed Central

Dumanis, Sonya B.; Ullrich, Lauren; Washington, Patricia M.; Forcelli, Patrick A.

2013-01-01

Grantsmanship is an integral component of surviving and thriving in academic science, especially in the current funding climate. Therefore, any additional opportunities to write, read, and review grants during graduate school may have lasting benefits on one's career. We present here our experience with a small, student-run grant program at Georgetown University Medical Center. Founded in 2010, this program has several goals: 1) to give graduate students an opportunity to conduct small, independent research projects; 2) to encourage graduate students to write grants early and often; and 3) to give graduate students an opportunity to review grants. In the 3 yr since the program's start, 28 applications have been submitted, 13 of which were funded for a total of $40,000. From funded grants, students have produced abstracts and manuscripts, generated data to support subsequent grant proposals, and made new professional contacts with collaborators. Above and beyond financial support, this program provided both applicants and reviewers an opportunity to improve their writing skills, professional development, and understanding of the grants process, as reflected in the outcome measures presented. With a small commitment of time and funding, other institutions could implement a program like this to the benefit of their graduate students. PMID:24006391

The demographic dynamics of small island societies.

PubMed

Cruz, M; D'ayala, P G; Marcus, E; Mcelroy, J L; Rossi, O

1987-01-01

Small islands and microstates have demonstrated a unique demographic pattern, including cycles of swift population increases or decreases well beyond natural birth and death rate balances. These demographic fluctuations have been produced largely by rises or declines in market opportunities. The process of taking advantage of favorable opportunities is always followed by a specialization in the given activity, without regard to environmental protection issues or a longterm strategy for economic development and resource diversification. The population growth phase is associated with increasing fragility of the economic base, whether because of the external dangers of overspecialization or induced internal dysfunctions such as disease and resource depletion. Eventually complete collapse results, causing chronic outmigration or even depopulation. Case histories of maritime basins in the Mediterranean, Caribbean, and Pacific show that the demographic structure of small islands has been particularly sensitive to changing economic opportunities, the vagaries of market forces, and cataclysmic natural events. Experience in these areas suggests that balanced economic development of small islands should be based on diversification of activities, thus ensuring a relatively stable pattern of growth, sound environmental management, and control of dangerous demographic fluctuations. Special attention should be given to the development of broad-based research and cooperation to integrate specific island opportunities within a regional network.

Newly Branded Energy Systems Integration Group Joins International

Science.gov Websites

research fellow at NREL. Likewise, UVIG sees opportunity in partnering with iiESI. The international Group Joins International Institute for Energy Systems Integration Newly Branded Energy Systems Integration Group Joins International Institute for Energy Systems Integration March 22, 2018 The world of

[Development of integrated support software for clinical nutrition].

PubMed

Siquier Homar, Pedro; Pinteño Blanco, Manel; Calleja Hernández, Miguel Ángel; Fernández Cortés, Francisco; Martínez Sotelo, Jesús

2015-09-01

to develop an integrated computer software application for specialized nutritional support, integrated in the electronic clinical record, which detects automatically and early those undernourished patients or at risk of developing undernourishment, determining points of opportunity for improvement and evaluation of the results. the quality standards published by the Nutrition Work Group of the Spanish Society of Hospital Pharmacy (SEFH) and the recommendations by the Pharmacy Group of the Spanish Society of Parenteral and Enteral Nutrition (SENPE) have been taken into account. According to these quality standards, the nutritional support has to include the following healthcare stages or sub-processes: nutritional screening, nutritional assessment, plan for nutritional care, prescription, preparation and administration. this software allows to conduct, in an automated way, a specific nutritional assessment for those patients with nutritional risk, implementing, if necessary, a nutritional treatment plan, conducting follow-up and traceability of outcomes derived from the implementation of improvement actions, and quantifying to what extent our practice is close to the established standard. this software allows to standardize the specialized nutritional support from a multidisciplinary point of view, introducing the concept of quality control per processes, and including patient as the main customer. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

Process oriented guided inquiry learning (POGIL®) marginally effects student achievement measures but substantially increases the odds of passing a course.

PubMed

Walker, Lindsey; Warfa, Abdi-Rizak M

2017-01-01

While the inquiry approach to science teaching has been widely recommended as an epistemic mechanism to promote deep content understanding, there is also increased expectation that process and other transferable skills should be integral part of science pedagogy. To test the hypothesis that coupling process skills to content teaching impacts academic success measures, we meta-analyzed twenty-one studies (n = 21) involving 7876 students that compared Process Oriented Guided Inquiry Learning (POGIL), a pedagogy that provides opportunities for improving process skills during content learning through guided-inquiry activities, to standard lecture conditions. Based on conventional measures of class performance, POGIL had a small effect on achievement outcomes (effect size = 0.29, [95% CI = 0.15-0.43]) but substantially improved the odds of passing a class (odds ratio = 2.02, [95% CI: 1.45-2.83]). That is, participants in the POGIL pedagogy had higher odds of passing a course and roughly performed 0.3 standard deviations higher on achievement measures than participants in standard lectures. In relative risk terms, POGIL reduced the risk of failing a course by 38%. These findings suggest providing opportunities to improve process skills during class instruction does not inhibit content learning but enhances conventional success measures. We compare these findings with those of recent large meta-analysis that examined the effects of global active learning methods on achievement outcomes and course failure rates in science, technology, engineering, and mathematics (STEM) fields.

Process oriented guided inquiry learning (POGIL®) marginally effects student achievement measures but substantially increases the odds of passing a course

PubMed Central

Walker, Lindsey

2017-01-01

While the inquiry approach to science teaching has been widely recommended as an epistemic mechanism to promote deep content understanding, there is also increased expectation that process and other transferable skills should be integral part of science pedagogy. To test the hypothesis that coupling process skills to content teaching impacts academic success measures, we meta-analyzed twenty-one studies (n = 21) involving 7876 students that compared Process Oriented Guided Inquiry Learning (POGIL), a pedagogy that provides opportunities for improving process skills during content learning through guided-inquiry activities, to standard lecture conditions. Based on conventional measures of class performance, POGIL had a small effect on achievement outcomes (effect size = 0.29, [95% CI = 0.15–0.43]) but substantially improved the odds of passing a class (odds ratio = 2.02, [95% CI: 1.45–2.83]). That is, participants in the POGIL pedagogy had higher odds of passing a course and roughly performed 0.3 standard deviations higher on achievement measures than participants in standard lectures. In relative risk terms, POGIL reduced the risk of failing a course by 38%. These findings suggest providing opportunities to improve process skills during class instruction does not inhibit content learning but enhances conventional success measures. We compare these findings with those of recent large meta-analysis that examined the effects of global active learning methods on achievement outcomes and course failure rates in science, technology, engineering, and mathematics (STEM) fields. PMID:29023502

Where Public Health Meets Human Rights: Integrating Human Rights into the Validation of the Elimination of Mother-to-Child Transmission of HIV and Syphilis.

PubMed

Kismödi, Eszter; Kiragu, Karusa; Sawicki, Olga; Smith, Sally; Brion, Sophie; Sharma, Aditi; Mworeko, Lilian; Iovita, Alexandrina

2017-12-01

In 2014, the World Health Organization (WHO) initiated a process for validation of the elimination of mother-to-child transmission (EMTCT) of HIV and syphilis by countries. For the first time in such a process for the validation of disease elimination, WHO introduced norms and approaches that are grounded in human rights, gender equality, and community engagement. This human rights-based validation process can serve as a key opportunity to enhance accountability for human rights protection by evaluating EMTCT programs against human rights norms and standards, including in relation to gender equality and by ensuring the provision of discrimination-free quality services. The rights-based validation process also involves the assessment of participation of affected communities in EMTCT program development, implementation, and monitoring and evaluation. It brings awareness to the types of human rights abuses and inequalities faced by women living with, at risk of, or affected by HIV and syphilis, and commits governments to eliminate those barriers. This process demonstrates the importance and feasibility of integrating human rights, gender, and community into key public health interventions in a manner that improves health outcomes, legitimizes the participation of affected communities, and advances the human rights of women living with HIV.

Improve your marketing effectiveness and net income through better prospecting.

PubMed

Gombeski, William R; Kantor, David; Bendycki, Nadine A; Wack, Jeff

2002-01-01

Prospecting is the process of finding customers who are ready to buy and can generate high net income for an organization. Leads for prospects come from three categories of sources: (1) organization-initiated; (2) acquired leads; and (3) marketing activity-initiated leads. Findings from a study of academic medical organizations showed a modest use of effective prospecting by hospitals surveyed and that there are opportunities to increase database marketing efforts. The data suggests that prospecting and its companion concept of qualifying are not fully integrated into many healthcare organization's marketing strategies and tactics.

Reducing Demand through Efficiency and Services: Impacts and Opportunities in Buildings Sector (Carbon Cycle 2.0)

ScienceCinema

Piette, Mary Ann

2018-05-03

Mary Ann Piette, Deputy of LBNL's Building Technologies Department and Director of the Demand Response Research Center, speaks at the Carbon Cycle 2.0 kick-off symposium Feb. 2, 2010. We emit more carbon into the atmosphere than natural processes are able to remove - an imbalance with negative consequences. Carbon Cycle 2.0 is a Berkeley Lab initiative to provide the science needed to restore this balance by integrating the Labs diverse research activities and delivering creative solutions toward a carbon-neutral energy future.

Reducing Demand through Efficiency and Services: Impacts and Opportunities in Buildings Sector (Carbon Cycle 2.0)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Piette, Mary Ann

Mary Ann Piette, Deputy of LBNL's Building Technologies Department and Director of the Demand Response Research Center, speaks at the Carbon Cycle 2.0 kick-off symposium Feb. 2, 2010. We emit more carbon into the atmosphere than natural processes are able to remove - an imbalance with negative consequences. Carbon Cycle 2.0 is a Berkeley Lab initiative to provide the science needed to restore this balance by integrating the Labs diverse research activities and delivering creative solutions toward a carbon-neutral energy future.

Interdisciplinary research and education at the biology-engineering-computer science interface: a perspective.

PubMed

Tadmor, Brigitta; Tidor, Bruce

2005-09-01

Progress in the life sciences, including genome sequencing and high-throughput experimentation, offers an opportunity for understanding biology and medicine from a systems perspective. This 'new view', which complements the more traditional component-based approach, involves the integration of biological research with approaches from engineering disciplines and computer science. The result is more than a new set of technologies. Rather, it promises a fundamental reconceptualization of the life sciences based on the development of quantitative and predictive models to describe crucial processes. To achieve this change, learning communities are being formed at the interface of the life sciences, engineering and computer science. Through these communities, research and education will be integrated across disciplines and the challenges associated with multidisciplinary team-based science will be addressed.

In-Situ Resource Utilization Experiment for the Asteroid Redirect Crewed Mission

NASA Astrophysics Data System (ADS)

Elliott, J.; Fries, M.; Love, S.; Sellar, R. G.; Voecks, G.; Wilson, D.

2015-10-01

The Asteroid Redirect Crewed Mission (ARCM) represents a unique opportunity to perform in-situ testing of concepts that could lead to full-scale exploitation of asteroids for their valuable resources [1]. This paper describes a concept for an astronautoperated "suitcase" experiment to would demonstrate asteroid volatile extraction using a solar-heated oven and integral cold trap in a configuration scalable to full-size asteroids. Conversion of liberated water into H2 and O2 products would also be demonstrated through an integral processing and storage unit. The plan also includes development of a local prospecting system consisting of a suit-mounted multi-spectral imager to aid the crew in choosing optimal samples, both for In-Situ Resource Utilization (ISRU) and for potential return to Earth.

Ultralow-Loss CMOS Copper Plasmonic Waveguides.

PubMed

Fedyanin, Dmitry Yu; Yakubovsky, Dmitry I; Kirtaev, Roman V; Volkov, Valentyn S

2016-01-13

Surface plasmon polaritons can give a unique opportunity to manipulate light at a scale well below the diffraction limit reducing the size of optical components down to that of nanoelectronic circuits. At the same time, plasmonics is mostly based on noble metals, which are not compatible with microelectronics manufacturing technologies. This prevents plasmonic components from integration with both silicon photonics and silicon microelectronics. Here, we demonstrate ultralow-loss copper plasmonic waveguides fabricated in a simple complementary metal-oxide semiconductor (CMOS) compatible process, which can outperform gold plasmonic waveguides simultaneously providing long (>40 μm) propagation length and deep subwavelength (∼λ(2)/50, where λ is the free-space wavelength) mode confinement in the telecommunication spectral range. These results create the backbone for the development of a CMOS plasmonic platform and its integration in future electronic chips.

Soft bioelectronics using nanomaterials

NASA Astrophysics Data System (ADS)

Lee, Hyunjae; Kim, Dae-Hyeong

2016-09-01

Recently, soft bioelectronics has attracted significant attention because of its potential applications in biointegrated healthcare devices and minimally invasive surgical tools. Mechanical mismatch between conventional electronic/optoelectronic devices and soft human tissues/organs, however, causes many challenges in materials and device designs of bio-integrated devices. Intrinsically soft hybrid materials comprising twodimensional nanomaterials are utilized to solve these issues. In this paper, we describe soft bioelectronic devices based on graphene synthesized by a chemical vapor deposition process. These devices have unique advantages over rigid electronics, particularly in biomedical applications. The functionalized graphene is hybridized with other nanomaterials and fabricated into high-performance sensors and actuators toward wearable and minimally invasive healthcare devices. Integrated bioelectronic systems constructed using these devices solve pending issues in clinical medicine while providing new opportunities in personalized healthcare.

Integration Science and Technology of Silicon-Based Ceramics and Composites:Technical Challenges and Opportunities

NASA Technical Reports Server (NTRS)

Singh, M.

2013-01-01

Ceramic integration technologies enable hierarchical design and manufacturing of intricate ceramic and composite parts starting with geometrically simpler units that are subsequently joined to themselves and/or to metals to create components with progressively higher levels of complexity and functionality. However, for the development of robust and reliable integrated systems with optimum performance for high temperature applications, detailed understanding of various thermochemical and thermomechanical factors is critical. Different technical approaches are required for the integration of ceramic to ceramic and ceramic to metal systems. Active metal brazing, in particular, is a simple and cost-effective method to integrate ceramic to metallic components. Active braze alloys usually contain a reactive filler metal (e.g., Ti, Cr, V, Hf etc) that promotes wettability and spreading by inducing chemical reactions with the ceramics and composites. In this presentation, various examples of brazing of silicon nitride to themselves and to metallic systems are presented. Other examples of joining of ceramic composites (C/SiC and SiC/SiC) using ceramic interlayers and the resulting microstructures are also presented. Thermomechanical characterization of joints is presented for both types of systems. In addition, various challenges and opportunities in design, fabrication, and testing of integrated similar (ceramic-ceramic) and dissimilar (ceramic-metal) material systems will be discussed. Potential opportunities and need for the development of innovative design philosophies, approaches, and integrated system testing under simulated application conditions will also be presented.

An Evaluation of the Factor Structure of the HRM Survey, Forms 9 and 11

DTIC Science & Technology

1976-07-01

Equal Opportunity Index, Social Problems and Processes Equal ...5 2 Equal 64-67 (Form 9) Opportunity 65-68,70 (Form 11) Equal Opportunity, Social Problems and Processes Equal Opportunity, Social ... Social Problems Equal Opportunity Index, Social Problems Drug Abuse Index, Social Problems Alcholism Prevention Index, Social Problems

Airborne Remote Sensing (ARS) for Agricultural Research and Commercialization Applications

NASA Technical Reports Server (NTRS)

Narayanan, Ram; Bowen, Brent D.; Nickerson, Jocelyn S.

2002-01-01

Tremendous advances in remote sensing technology and computing power over the last few decades are now providing scientists with the opportunity to investigate, measure, and model environmental patterns and processes with increasing confidence. Such advances are being pursued by the Nebraska Remote Sensing Facility, which consists of approximately 30 faculty members and is very competitive with other institutions in the depth of the work that is accomplished. The development of this facility targeted at applications, commercialization, and education programs in the area of precision agriculture provides a unique opportunity. This critical area is within the scope of NASA goals and objectives of NASA s Applications, Technology Transfer, Commercialization, and Education Division and the Earth Science Enterprise. This innovative integration of Aerospace (Aeronautics) Technology Enterprise applications with other NASA enterprises serves as a model of cross-enterprise transfer of science with specific commercial applications.

Deploying Innovation

Science.gov Websites

; Sponsored Work Regional Economic Development Technology Opportunities User Facilities About Us Metrics In diverse economic development. With an integrated portfolio of R&D work, we leverage partnerships with Partnerships & Sponsored Work Regional Economic Development Technology Opportunities User Facilities

Creating Robust STEM Research Ecosystems in Schools: Joining the Dots for Young Researchers

NASA Astrophysics Data System (ADS)

Pritchard, M.; Ibarra, D. L.

2017-12-01

Developing an intelligent curiosity about the world in school-aged learners is one of the key purposes of education. Nurturing this intelligent curiosity in a systematic and integrated manner is essential for rigorous, scientific literacy, which in turn inspires advanced research and innovation in post-school life. STEM (Science, Technology, Engineering, and Mathematics) education has been widely adopted as the conceptual framework to achieve this goal. For young learners, their experienced world is largely confined to the spaces within the boundaries of educational institutions. This type of environment might be perceived as sterile or even hostile to genuine research, as institutional endeavor is largely shaped by examination syllabi. This can be changed by viewing the school as a living laboratory of processes and products, all of which offer enormous potential for meaningful and valuable student-led STEM research. Creating research-focused ecosystems within schools, however, requires considerable effort to create a learning culture that defragments knowledge systems and connects isolated pools of inquiry. The existing parameters and processes of school ecosystems, such as energy generation, consumption, waste creation and disposal offer opportunities for school students to utilize STEM-related skills observe and measure their own ecological footprint, undertake research into these living processes in an integrated manner, and develop solutions to create closed loops of optimally managed and measured consumption with the institution. For example, connecting a deep understanding of the principles of renewable energy generation with close, real-time monitoring of classroom energy usage creates the opportunity to develop a higher level of user awareness and more optimized consumption habits. Food waste, when composted and recycled on-site, similarly offers the potential to connect the sociological issue of excess consumption with a scientific understanding of aerobic and anaerobic decomposition and the subsequent purposes to which the product of the process might be put. In adopting a STEM framework to examine and shape school ecosystems, young researchers develop the capacity to observe, measure, analyze, troubleshoot, and optimize their own environment.

Multiscale Integration of -Omic, Imaging, and Clinical Data in Biomedical Informatics

PubMed Central

Phan, John H.; Quo, Chang F.; Cheng, Chihwen; Wang, May Dongmei

2016-01-01

This paper reviews challenges and opportunities in multiscale data integration for biomedical informatics. Biomedical data can come from different biological origins, data acquisition technologies, and clinical applications. Integrating such data across multiple scales (e.g., molecular, cellular/tissue, and patient) can lead to more informed decisions for personalized, predictive, and preventive medicine. However, data heterogeneity, community standards in data acquisition, and computational complexity are big challenges for such decision making. This review describes genomic and proteomic (i.e., molecular), histopathological imaging (i.e., cellular/tissue), and clinical (i.e., patient) data; it includes case studies for single-scale (e.g., combining genomic or histopathological image data), multiscale (e.g., combining histopathological image and clinical data), and multiscale and multiplatform (e.g., the Human Protein Atlas and The Cancer Genome Atlas) data integration. Numerous opportunities exist in biomedical informatics research focusing on integration of multiscale and multiplatform data. PMID:23231990

Multiscale integration of -omic, imaging, and clinical data in biomedical informatics.

PubMed

Phan, John H; Quo, Chang F; Cheng, Chihwen; Wang, May Dongmei

2012-01-01

This paper reviews challenges and opportunities in multiscale data integration for biomedical informatics. Biomedical data can come from different biological origins, data acquisition technologies, and clinical applications. Integrating such data across multiple scales (e.g., molecular, cellular/tissue, and patient) can lead to more informed decisions for personalized, predictive, and preventive medicine. However, data heterogeneity, community standards in data acquisition, and computational complexity are big challenges for such decision making. This review describes genomic and proteomic (i.e., molecular), histopathological imaging (i.e., cellular/tissue), and clinical (i.e., patient) data; it includes case studies for single-scale (e.g., combining genomic or histopathological image data), multiscale (e.g., combining histopathological image and clinical data), and multiscale and multiplatform (e.g., the Human Protein Atlas and The Cancer Genome Atlas) data integration. Numerous opportunities exist in biomedical informatics research focusing on integration of multiscale and multiplatform data.

Financial risk management of pharmacy benefits.

PubMed

Saikami, D

1997-10-01

Financial risk management of pharmacy benefits in integrated health systems is explained. A managed care organization should assume financial risk for pharmacy benefits only if it can manage the risk. Horizontally integrated organizations often do not have much control over the management of drug utilization and costs. Vertically integrated organizations have the greatest ability to manage pharmacy financial risk; virtual integration may also be compatible. Contracts can be established in which the provider is incentivized or placed at partial or full risk. The main concerns that health plans have with respect to pharmacy capitation are formulary management and the question of who should receive rebates from manufacturers. The components needed to managed pharmacy financial risk depend on the type of contract negotiated. Health-system pharmacists are uniquely positioned to take advantage of opportunities opening up through pharmacy risk contracting. Functions most organizations must provide when assuming pharmacy financial risk can be divided into internal and external categories. Internally performed functions include formulary management, clinical pharmacy services and utilization management, and utilization reports for physicians. Functions that can be outsourced include claims processing and administration, provider- and customer support services, and rebates. Organizations that integrate the pharmacy benefit across the health care continuum will be more effective in controlling costs and improving outcomes than organizations that handle this benefit as separate from others. Patient care should not focus on payment mechanisms and unit costs but on developing superior processes and systems that improve health care.

Multi-material optoelectronic fiber devices

NASA Astrophysics Data System (ADS)

Sorin, F.; Yan, Wei; Volpi, Marco; Page, Alexis G.; Nguyen Dang, Tung; Qu, Y.

2017-05-01

The recent ability to integrate materials with different optical and optoelectronic properties in prescribed architectures within flexible fibers is enabling novel opportunities for advanced optical probes, functional surfaces and smart textiles. In particular, the thermal drawing process has known a series of breakthroughs in recent years that have expanded the range of materials and architectures that can be engineered within uniform fibers. Of particular interest in this presentation will be optoelectronic fibers that integrate semiconductors electrically addressed by conducting materials. These long, thin and flexible fibers can intercept optical radiation, localize and inform on a beam direction, detect its wavelength and even harness its energy. They hence constitute ideal candidates for applications such as remote and distributed sensing, large-area optical-detection arrays, energy harvesting and storage, innovative health care solutions, and functional fabrics. To improve performance and device complexity, tremendous progresses have been made in terms of the integrated semiconductor architectures, evolving from large fiber solid-core, to sub-hundred nanometer thin-films, nano-filaments and even nanospheres. To bridge the gap between the optoelectronic fiber concept and practical applications however, we still need to improve device performance and integration. In this presentation we will describe the materials and processing approaches to realize optoelectronic fibers, as well as give a few examples of demonstrated systems for imaging as well as light and chemical sensing. We will then discuss paths towards practical applications focusing on two main points: fiber connectivity, and improving the semiconductor microstructure by developing scalable approaches to make fiber-integrated single-crystal nanowire based devices.

A Recipe for Streamlining Mission Management

NASA Technical Reports Server (NTRS)

Mitchell, Andrew E.; Semancik, Susan K.

2004-01-01

This paper describes a project's design and implementation for streamlining mission management with knowledge capture processes across multiple organizations of a NASA directorate. Thc project's focus is on standardizing processes and reports; enabling secure information access and case of maintenance; automating and tracking appropriate workflow rules through process mapping; and infusing new technologies. This paper will describe a small team's experiences using XML technologies through an enhanced vendor suite of applications integrated on Windows-based platforms called the Wallops Integrated Scheduling and Document Management System (WISDMS). This paper describes our results using this system in a variety of endeavors, including providing range project scheduling and resource management for a Range and Mission Management Office; implementing an automated Customer Feedback system for a directorate; streamlining mission status reporting across a directorate; and initiating a document management, configuration management and portal access system for a Range Safety Office's programs. The end result is a reduction of the knowledge gap through better integration and distribution of information, improved process performance, automated metric gathering, and quicker identification of problem areas and issues. However, the real proof of the pudding comes through overcoming the user's reluctance to replace familiar, seasoned processes with new technology ingredients blended with automated procedures in an untested recipe. This paper shares some of the team's observations that led to better implementation techniques, as well as an IS0 9001 Best Practices citation. This project has provided a unique opportunity to advance NASA's competency in new technologies, as well as to strategically implement them within an organizational structure, while wetting the appetite for continued improvements in mission management.

Integrative modelling for One Health: pattern, process and participation

PubMed Central

Redding, D. W.; Wood, J. L. N.

2017-01-01

This paper argues for an integrative modelling approach for understanding zoonoses disease dynamics, combining process, pattern and participatory models. Each type of modelling provides important insights, but all are limited. Combining these in a ‘3P’ approach offers the opportunity for a productive conversation between modelling efforts, contributing to a ‘One Health’ agenda. The aim is not to come up with a composite model, but seek synergies between perspectives, encouraging cross-disciplinary interactions. We illustrate our argument with cases from Africa, and in particular from our work on Ebola virus and Lassa fever virus. Combining process-based compartmental models with macroecological data offers a spatial perspective on potential disease impacts. However, without insights from the ground, the ‘black box’ of transmission dynamics, so crucial to model assumptions, may not be fully understood. We show how participatory modelling and ethnographic research of Ebola and Lassa fever can reveal social roles, unsafe practices, mobility and movement and temporal changes in livelihoods. Together with longer-term dynamics of change in societies and ecologies, all can be important in explaining disease transmission, and provide important complementary insights to other modelling efforts. An integrative modelling approach therefore can offer help to improve disease control efforts and public health responses. This article is part of the themed issue ‘One Health for a changing world: zoonoses, ecosystems and human well-being’. PMID:28584172

Integrated response toward HIV: a health promotion case study from China.

PubMed

Jiang, Zhen; Wang, Debin; Yang, Sen; Duan, Mingyue; Bu, Pengbin; Green, Andrew; Zhang, Xuejun

2011-06-01

Integrated HIV response refers to a formalized, collaborative process among organizations in communities with HIV at-risk populations. It is a both comprehensive and flexible scheme, which may include community-based environment promotion, skill coalition, fund linkage, human resource collaboration and service system jointly for both HIV prevention and control. It enables decisions and actions responds over time. In 1997, the Chinese government developed a 10-year HIV project supported by World Bank Loan (H9-HIV/AIDS/STIs). It was the first integrated STI/HIV intervention project in China and provides a unique opportunity to explore the long-term comprehensive STI/HIV intervention in a low-middle income country setting. Significant outcomes were identified as development and promotion of the national strategic plan and its ongoing implementation; positive knowledge, behavioral and STI/HIV prevalence rate change; and valuable experiences for managing integrated HIV/STI intervention projects. Essential factors for the success of the project and the key tasks for the next step were identified and included well-designed intervention in rural and low economic regions, unified program evaluation framework and real-time information collection and assessment.

Integrated Quantitative Cancer Risk Assessment of Inorganic Arsenic

EPA Science Inventory

This paper attempts to make an integrated risk assessment of arsenic, using data on humans exposed to arsenic via inhalation and ingestion. he data useful for making an integrated analysis and data gaps are discussed. rsenic provides a rare opportunity to compare the cancer risk ...

Ceramic Integration Technologies for Advanced Energy Systems: Critical Needs, Technical Challenges, and Opportunities

NASA Technical Reports Server (NTRS)

Singh, Mrityunjay

2010-01-01

Advanced ceramic integration technologies dramatically impact the energy landscape due to wide scale application of ceramics in all aspects of alternative energy production, storage, distribution, conservation, and efficiency. Examples include fuel cells, thermoelectrics, photovoltaics, gas turbine propulsion systems, distribution and transmission systems based on superconductors, nuclear power generation and waste disposal. Ceramic integration technologies play a key role in fabrication and manufacturing of large and complex shaped parts with multifunctional properties. However, the development of robust and reliable integrated systems with optimum performance requires the understanding of many thermochemical and thermomechanical factors, particularly for high temperature applications. In this presentation, various needs, challenges, and opportunities in design, fabrication, and testing of integrated similar (ceramic ceramic) and dissimilar (ceramic metal) material www.nasa.gov 45 ceramic-ceramic-systems have been discussed. Experimental results for bonding and integration of SiC based Micro-Electro-Mechanical-Systems (MEMS) LDI fuel injector and advanced ceramics and composites for gas turbine applications are presented.

Clinical modeling--a critical analysis.

PubMed

Blobel, Bernd; Goossen, William; Brochhausen, Mathias

2014-01-01

Modeling clinical processes (and their informational representation) is a prerequisite for optimally enabling and supporting high quality and safe care through information and communication technology and meaningful use of gathered information. The paper investigates existing approaches to clinical modeling, thereby systematically analyzing the underlying principles, the consistency with and the integration opportunity to other existing or emerging projects, as well as the correctness of representing the reality of health and health services. The analysis is performed using an architectural framework for modeling real-world systems. In addition, fundamental work on the representation of facts, relations, and processes in the clinical domain by ontologies is applied, thereby including the integration of advanced methodologies such as translational and system medicine. The paper demonstrates fundamental weaknesses and different maturity as well as evolutionary potential in the approaches considered. It offers a development process starting with the business domain and its ontologies, continuing with the Reference Model-Open Distributed Processing (RM-ODP) related conceptual models in the ICT ontology space, the information and the computational view, and concluding with the implementation details represented as engineering and technology view, respectively. The existing approaches reflect at different levels the clinical domain, put the main focus on different phases of the development process instead of first establishing the real business process representation and therefore enable quite differently and partially limitedly the domain experts' involvement. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

Integrated Payload Data Handling Systems Using Software Partitioning

NASA Astrophysics Data System (ADS)

Taylor, Alun; Hann, Mark; Wishart, Alex

2015-09-01

An integrated Payload Data Handling System (I-PDHS) is one in which multiple instruments share a central payload processor for their on-board data processing tasks. This offers a number of advantages over the conventional decentralised architecture. Savings in payload mass and power can be realised because the total processing resource is matched to the requirements, as opposed to the decentralised architecture here the processing resource is in effect the sum of all the applications. Overall development cost can be reduced using a common processor. At individual instrument level the potential benefits include a standardised application development environment, and the opportunity to run the instrument data handling application on a fully redundant and more powerful processing platform [1]. This paper describes a joint program by SCISYS UK Limited, Airbus Defence and Space, Imperial College London and RAL Space to implement a realistic demonstration of an I-PDHS using engineering models of flight instruments (a magnetometer and camera) and a laboratory demonstrator of a central payload processor which is functionally representative of a flight design. The objective is to raise the Technology Readiness Level of the centralised data processing technique by address the key areas of task partitioning to prevent fault propagation and the use of a common development process for the instrument applications. The project is supported by a UK Space Agency grant awarded under the National Space Technology Program SpaceCITI scheme. [1].

Discovering eHealth Technology: An Innovative Interprofessional Graduate Student Learning Experience.

PubMed

Estes, Krista; Gilliam, Eric; Knapfel, Sarah; Lee, Chanmi; Skiba, Diane

2016-01-01

The use of eHealth has grown in recent years and is projected to continue to increase exponentially. In order to empower and prepare advanced practice providers to integrate eHealth into their clinical practice, curricular changes need to occur. The iTEAM grant provides a unique opportunity to prepare advanced practice disciplines to provide collaborative care using eHealth. Through the integration of a simulated telehealth using a standardized patient, Doctor of Pharmacy and Advanced Practice Registered Nursing students learned how to apply health information technology and coordinate care in an interprofessional manner. Opportunities and challenges to guide future efforts to integrate eHealth-learning experiences into the curriculum are identified.

Administrative Challenges to the Integration of Oral Health With Primary Care

PubMed Central

Maxey, Hannah L.; Randolph, Courtney; Gano, Laura; Kochhar, Komal

2017-01-01

Inadequate access to preventive oral health services contributes to oral health disparities and is a major public health concern in the United States. Federally Qualified Health Centers play a critical role in improving access to care for populations affected by oral health disparities but face a number of administrative challenges associated with implementation of oral health integration models. We conducted a SWOT (strengths, weaknesses, opportunities, and threats) analysis with health care executives to identify strengths, weaknesses, opportunities, and threats of successful oral health integration in Federally Qualified Health Centers. Four themes were identified: (1) culture of health care organizations; (2) operations and administration; (3) finance; and (4) workforce. PMID:27218701

Fostering professional formation in residency: development and evaluation of the "forum" seminar series.

PubMed

Nothnagle, Melissa; Reis, Shmuel; Goldman, Roberta E; Anandarajah, Gowri

2014-01-01

Residency training is a critical time for physicians' professional formation. However, few structured interventions exist to support residents in this transformative process of integrating personal and professional values, a process that is essential to physician identity formation and preservation of core values such as service and compassion. The authors created a seminar series, the "Forum," to support resident professional formation and address the hidden curriculum as part of a larger intervention to support self-directed learning skills such as goal setting and reflection. Ninety-minute sessions with senior residents and faculty held every other month include opportunities for individual reflection, small- and large-group discussion, and brief didactic components focused on skills such as teaching and leadership. The qualitative program evaluation included analyses of individual semistructured interviews with resident and faculty participants from 2008 to 2011 and of notes recorded by an observer during the 1st year's sessions. Residents appreciated the focus on relevant issues, presence of faculty, opportunities for reflection and interactivity, and inclusion of practical skills. Effects attributed to the Forum included gaining practical skills, feeling a deeper connection to one another and a sense of community, and recognizing progress in their own professional development and growth. Elements described in the literature as essential to professional formation, including encouraging reflection, use of narrative, role modeling, addressing the hidden curriculum, and fostering an authentic community, were recognized by participants as integral to the Forum's success. A group forum for reflection and discussion with peers and role models, tailored to local needs, offers an effective structure to foster professional formation in residency.

The Reactive Species Interactome: Evolutionary Emergence, Biological Significance, and Opportunities for Redox Metabolomics and Personalized Medicine.

PubMed

Cortese-Krott, Miriam M; Koning, Anne; Kuhnle, Gunter G C; Nagy, Peter; Bianco, Christopher L; Pasch, Andreas; Wink, David A; Fukuto, Jon M; Jackson, Alan A; van Goor, Harry; Olson, Kenneth R; Feelisch, Martin

2017-10-01

Oxidative stress is thought to account for aberrant redox homeostasis and contribute to aging and disease. However, more often than not, administration of antioxidants is ineffective, suggesting that our current understanding of the underlying regulatory processes is incomplete. Recent Advances: Similar to reactive oxygen species and reactive nitrogen species, reactive sulfur species are now emerging as important signaling molecules, targeting regulatory cysteine redox switches in proteins, affecting gene regulation, ion transport, intermediary metabolism, and mitochondrial function. To rationalize the complexity of chemical interactions of reactive species with themselves and their targets and help define their role in systemic metabolic control, we here introduce a novel integrative concept defined as the reactive species interactome (RSI). The RSI is a primeval multilevel redox regulatory system whose architecture, together with the physicochemical characteristics of its constituents, allows efficient sensing and rapid adaptation to environmental changes and various other stressors to enhance fitness and resilience at the local and whole-organism level. To better characterize the RSI-related processes that determine fluxes through specific pathways and enable integration, it is necessary to disentangle the chemical biology and activity of reactive species (including precursors and reaction products), their targets, communication systems, and effects on cellular, organ, and whole-organism bioenergetics using system-level/network analyses. Understanding the mechanisms through which the RSI operates will enable a better appreciation of the possibilities to modulate the entire biological system; moreover, unveiling molecular signatures that characterize specific environmental challenges or other forms of stress will provide new prevention/intervention opportunities for personalized medicine. Antioxid. Redox Signal. 00, 000-000.

Somatic Embryogenesis in Coffee: The Evolution of Biotechnology and the Integration of Omics Technologies Offer Great Opportunities

PubMed Central

Campos, Nádia A.; Panis, Bart; Carpentier, Sebastien C.

2017-01-01

One of the most important crops cultivated around the world is coffee. There are two main cultivated species, Coffea arabica and C. canephora. Both species are difficult to improve through conventional breeding, taking at least 20 years to produce a new cultivar. Biotechnological tools such as genetic transformation, micropropagation and somatic embryogenesis (SE) have been extensively studied in order to provide practical results for coffee improvement. While genetic transformation got many attention in the past and is booming with the CRISPR technology, micropropagation and SE are still the major bottle neck and urgently need more attention. The methodologies to induce SE and the further development of the embryos are genotype-dependent, what leads to an almost empirical development of specific protocols for each cultivar or clone. This is a serious limitation and excludes a general comprehensive understanding of the process as a whole. The aim of this review is to provide an overview of which achievements and molecular insights have been gained in (coffee) somatic embryogenesis and encourage researchers to invest further in the in vitro technology and combine it with the latest omics techniques (genomics, transcriptomics, proteomics, metabolomics, and phenomics). We conclude that the evolution of biotechnology and the integration of omics technologies offer great opportunities to (i) optimize the production process of SE and the subsequent conversion into rooted plantlets and (ii) to screen for possible somaclonal variation. However, currently the usage of the latest biotechnology did not pass the stage beyond proof of potential and needs to further improve. PMID:28871271

Semi-automated software service integration in virtual organisations

NASA Astrophysics Data System (ADS)

Afsarmanesh, Hamideh; Sargolzaei, Mahdi; Shadi, Mahdieh

2015-08-01

To enhance their business opportunities, organisations involved in many service industries are increasingly active in pursuit of both online provision of their business services (BSs) and collaborating with others. Collaborative Networks (CNs) in service industry sector, however, face many challenges related to sharing and integration of their collection of provided BSs and their corresponding software services. Therefore, the topic of service interoperability for which this article introduces a framework is gaining momentum in research for supporting CNs. It contributes to generation of formal machine readable specification for business processes, aimed at providing their unambiguous definitions, as needed for developing their equivalent software services. The framework provides a model and implementation architecture for discovery and composition of shared services, to support the semi-automated development of integrated value-added services. In support of service discovery, a main contribution of this research is the formal representation of services' behaviour and applying desired service behaviour specified by users for automated matchmaking with other existing services. Furthermore, to support service integration, mechanisms are developed for automated selection of the most suitable service(s) according to a number of service quality aspects. Two scenario cases are presented, which exemplify several specific features related to service discovery and service integration aspects.

The European Plate Observing System (EPOS): Integrating Thematic Services for Solid Earth Science

NASA Astrophysics Data System (ADS)

Atakan, Kuvvet; Bailo, Daniele; Consortium, Epos

2016-04-01

The mission of EPOS is to monitor and understand the dynamic and complex Earth system by relying on new e-science opportunities and integrating diverse and advanced Research Infrastructures in Europe for solid Earth Science. EPOS will enable innovative multidisciplinary research for a better understanding of the Earth's physical and chemical processes that control earthquakes, volcanic eruptions, ground instability and tsunami as well as the processes driving tectonics and Earth's surface dynamics. Through integration of data, models and facilities EPOS will allow the Earth Science community to make a step change in developing new concepts and tools for key answers to scientific and socio-economic questions concerning geo-hazards and geo-resources as well as Earth sciences applications to the environment and to human welfare. EPOS, during its Implementation Phase (EPOS-IP), will integrate multidisciplinary data into a single e-infrastructure. Multidisciplinary data are organized and governed by the Thematic Core Services (TCS) and are driven by various scientific communities encompassing a wide spectrum of Earth science disciplines. These include Data, Data-products, Services and Software (DDSS), from seismology, near fault observatories, geodetic observations, volcano observations, satellite observations, geomagnetic observations, as well as data from various anthropogenic hazard episodes, geological information and modelling. In addition, transnational access to multi-scale laboratories and geo-energy test-beds for low-carbon energy will be provided. TCS DDSS will be integrated into Integrated Core Services (ICS), a platform that will ensure their interoperability and access to these services by the scientific community as well as other users within the society. This requires dedicated tasks for interactions with the various TCS-WPs, as well as the various distributed ICS (ICS-Ds), such as High Performance Computing (HPC) facilities, large scale data storage facilities, complex processing and visualization tools etc. Computational Earth Science (CES) services are identified as a transversal activity and is planned to be harmonized and provided within the ICS. Currently a comprehensive requirements and use cases elicitation process is started through interactions with the ten different Thematic Core Service work packages. The results of this will be used to harmonize the DDSS elements and prepare for interoperability across the various disciplines. For this purpose a dedicated workshop is planned where the representatives of all the TCS communities will jointly discuss and agree upon the harmonization process. The technical integration of the DDSS elements to a metadata structure adopting CERIF (Common European Research Information Format) standards will start after the harmonization process is completed. Various levels of maturity in the handling and availability of TCS specific DDSS elements among the different TCS groups, is one of the most challenging aspects of this integration. For this reason a roadmap for integration is being prepared where most mature DDSS elements will be implemented during the next 2 years after a community driven testing and validation process. Integration of the remaining DDSS elements will be a continuously evolving process in the coming years.

Modeling Resource Hotspots: Critical Linkages and Processes

NASA Astrophysics Data System (ADS)

Daher, B.; Mohtar, R.; Pistikopoulos, E.; McCarl, B. A.; Yang, Y.

2017-12-01

Growing demands for interconnected resources emerge in the form of hotspots of varying characteristics. The business as usual allocation model cannot address the current, let alone anticipated, complex and highly interconnected resource challenges we face. A new paradigm for resource allocation must be adopted: one that identifies cross-sectoral synergies and, that moves away from silos to recognition of the nexus and integration of it. Doing so will result in new opportunities for business growth, economic development, and improved social well-being. Solutions and interventions must be multi-faceted; opportunities should be identified with holistic trade-offs in mind. No single solution fits all: different hotspots will require distinct interventions. Hotspots have varying resource constraints, stakeholders, goals and targets. The San Antonio region represents a complex resource hotspot with promising potential: its rapidly growing population, the Eagle Ford shale play, and the major agricultural activity there makes it a hotspot with many competing demands. Stakeholders need tools to allow them to knowledgeably address impending resource challenges. This study will identify contemporary WEF nexus questions and critical system interlinkages that will inform the modeling of the tightly interconnected resource systems and stresses using the San Antonio Region as a base; it will conceptualize a WEF nexus modeling framework, and develop assessment criteria to inform integrative planning and decision making.

Powder Materials and Energy Efficiency in Transportation: Opportunities and Challenges

NASA Astrophysics Data System (ADS)

Marquis, Fernand D. S.

2012-03-01

The transportation industry accounts for one quarter of global energy use and has by far the largest share of global oil consumption. It used 51.5% of the oil worldwide in 2003. Mobility projections show that it is expected to triple by 2050 with associated energy use. Considerable achievements recently have been obtained in the development of powder and powder-processed metallic alloys, metal matrix composites, intermetallics, and carbon fiber composites. These achievements have resulted in their introduction to the transportation industry in a wide variety of transportation components with significant impact on energy efficiency. A significant number of nano, nanostructured, and nanohybrid materials systems have been deployed. Others, some of them incorporating carbon nanotubes and graphene, are under research and development and exhibit considerable potential. Airplane redesign using a materials and functional systems integration approach was used resulting in considerable system improvements and energy efficiency. It is expected that this materials and functional systems integration soon will be adopted in the design and manufacture of other advanced aircrafts and extended to the automotive industry and then to the marine transportation industry. The opportunities for the development and application of new powder materials in the transportation industry are extensive, with considerable potential to impact energy utilization. However, significant challenges need to be overcome in several critical areas.

Shared Decision-Making for Nursing Practice: An Integrative Review

PubMed Central

Truglio-Londrigan, Marie; Slyer, Jason T.

2018-01-01

Background: Shared decision-making has received national and international interest by providers, educators, researchers, and policy makers. The literature on shared decision-making is extensive, dealing with the individual components of shared decision-making rather than a comprehensive process. This view of shared decision-making leaves healthcare providers to wonder how to integrate shared decision-making into practice. Objective: To understand shared decision-making as a comprehensive process from the perspective of the patient and provider in all healthcare settings. Methods: An integrative review was conducted applying a systematic approach involving a literature search, data evaluation, and data analysis. The search included articles from PubMed, CINAHL, the Cochrane Central Register of Controlled Trials, and PsycINFO from 1970 through 2016. Articles included quantitative experimental and non-experimental designs, qualitative, and theoretical articles about shared decision-making between all healthcare providers and patients in all healthcare settings. Results: Fifty-two papers were included in this integrative review. Three categories emerged from the synthesis: (a) communication/ relationship building; (b) working towards a shared decision; and (c) action for shared decision-making. Each major theme contained sub-themes represented in the proposed visual representation for shared decision-making. Conclusion: A comprehensive understanding of shared decision-making between the nurse and the patient was identified. A visual representation offers a guide that depicts shared decision-making as a process taking place during a healthcare encounter with implications for the continuation of shared decisions over time offering patients an opportunity to return to the nurse for reconsiderations of past shared decisions. PMID:29456779

Lift outs: how to acquire a high-functioning team.

PubMed

Groysberg, Boris; Abrahams, Robin

2006-12-01

More and more, expanding companies are hiring high-functioning groups of people who have been working together effectively within one company and can rapidly come up to speed in a new environment. These lifted-out teams don't need to get acquainted with one another or to establish shared values, mutual accountability, or group norms; their long-standing relationships and trust help them make an impact very quickly. Of course, the process is not without risks: A failed lift out can lead to loss of money, opportunity, credibility, and even native talent. Boris Groysberg and Robin Abrahams studied more than 40 high-profile moves and interviewed team leaders in multiple industries and countries to examine the risks and opportunities that lift outs present. They concluded that, regardless of industry, nationality, or size of the team, a successful lift out unfolds over four consecutive, interdependent stages that must be meticulously managed. In the courtship stage, the hiring company and the leader of the targeted team determine whether the proposed move is, in fact, a good idea, and then define their business goals and discuss strategies. At the same time, the team leader discusses the potential move with the other members of his or her group to assess their level of interest and prepare them for the change. The second stage involves the integration of the team leader with the new company's top leadership. This part of the process ensures the team's access to senior executives-the most important factor in a lift out's success. Operational integration is the focus of the third stage. Ideally, teams will start out working with the same or similar clients, vendors, and industry standards. The fourth stage entails full cultural integration. To succeed, the lifted-out team members must be willing to re-earn credibility by proving their value and winning their new colleagues' trust.

Materials and structures technology insertion into spacecraft systems: Successes and challenges

NASA Astrophysics Data System (ADS)

Rawal, Suraj

2018-05-01

Over the last 30 years, significant advancements have led to the use of multifunctional materials and structures technologies in spacecraft systems. This includes the integration of adaptive structures, advanced composites, nanotechnology, and additive manufacturing technologies. Development of multifunctional structures has been directly influenced by the implementation of processes and tools for adaptive structures pioneered by Prof. Paolo Santini. Multifunctional materials and structures incorporating non-structural engineering functions such as thermal, electrical, radiation shielding, power, and sensors have been investigated. The result has been an integrated structure that offers reduced mass, packaging volume, and ease of integration for spacecraft systems. Current technology development efforts are being conducted to develop innovative multifunctional materials and structures designs incorporating advanced composites, nanotechnology, and additive manufacturing. However, these efforts offer significant challenges in the qualification and acceptance into spacecraft systems. This paper presents a brief overview of the technology development and successful insertion of advanced material technologies into spacecraft structures. Finally, opportunities and challenges to develop and mature next generation advanced materials and structures are presented.

Development of a general equation to determine the transfer factor feed-to-meat for radiocesium on the basis of the body mass of domestic animals

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nalezinski, S.; Ruehm, W.; Wirth, E.

1996-05-01

Transfer factors from feed to meat (5{sub {integral}}), taken from literature for monogastric animals and ruminants have been correlated to their corresponding animal body mass (m{sub b}). Taking all data into account, a close relationship between both transfer factor and body mass becomes evident, yielding a regression function of (T{sub {integral}} = 8.0 x m{sub b}{sup {minus}0.91}) (r = -0.97). For monogastric animals (including poultry), the corresponding relationships are T{sub {integral}} = 1.9 x m{sub b}{sup {minus}0.72} (r = 0.78). The equations offer the opportunity to estimate the transfer factor for individual animals more precisely taking individual body masses intomore » account. They are of interest for animals, on which no or only poor data concerning radiocesium transfer factors are available. The determination of radiocesium transfer factors are reduced to a simple weighing process. 17 refs., 1 fig., 2 tabs.« less

Microelectromechanical Systems for Aerodynamics Applications

NASA Technical Reports Server (NTRS)

Mehregany, Mehran; DeAnna, Russell G.; Reshotko, Eli

1996-01-01

Microelectromechanical systems (MEMS) embody the integration of sensors, actuators, and electronics on a single substrate using integrated circuit fabrication techniques and compatible micromachining processes. Silicon and its derivatives form the material base for the MEMS technology. MEMS devices, including micro-sensors and micro-actuators, are attractive because they can be made small (characteristic dimension about microns), be produced in large numbers with uniform performance, include electronics for high performance and sophisticated functionality, and be inexpensive. MEMS pressure sensors, wall-shear-stress sensors, and micromachined hot-wires are nearing application in aeronautics. MEMS actuators face a tougher challenge since they have to be scaled (up) to the physical phenomena that are being controlled. MEMS actuators are proposed, for example, for controlling the small structures in a turbulent boundary layer, for aircraft control, for cooling, and for mixing enhancement. Data acquisition or control logistics require integration of electronics along with the transducer elements with appropriate consideration of analog-to-digital conversion, multiplexing, and telemetry. Altogether, MEMS technology offers exciting opportunities for aerodynamics applications both in wind tunnels and in flight

Resilience mediated the association between acculturation and psychological growth in college students from Hong Kong to Guangzhou, China.

PubMed

Yu, Nancy Xiaonan; Liu, Chang; Yue, Zhenzhu

2017-08-01

The number of Hong Kong citizens living in mainland China is increasing. The process of acculturation may create opportunities for psychological growth. This study aimed at examining whether resilience mediated the effects of acculturation on psychological growth in college students from Hong Kong to Guangzhou. In this cross-sectional survey, 164 college students in Guangzhou who were Hong Kong permanent residents (female: 46%, age: 21.09 ± 1.50) joined the study. The integration group reported more psychological growth than the assimilation, separation, and marginalization groups. Resilience partially mediated the effect of integration on psychological growth and fully mediated the effect of marginalization on psychological growth. Resilience represents one of the mechanisms to explain beneficial effects of integration on psychological growth in college students from Hong Kong to Guangzhou. Theoretical considerations to rethink the acculturation model, implications for developing intervention programs, and recommendations for future research are discussed.

Sensing and Virtual Worlds - A Survey of Research Opportunities

NASA Technical Reports Server (NTRS)

Moore, Dana

2012-01-01

Virtual Worlds (VWs) have been used effectively in live and constructive military training. An area that remains fertile ground for exploration and a new vision involves integrating various traditional and now non-traditional sensors into virtual worlds. In this paper, we will assert that the benefits of this integration are several. First, we maintain that virtual worlds offer improved sensor deployment planning through improved visualization and stimulation of the model, using geo-specific terrain and structure. Secondly, we assert that VWs enhance the mission rehearsal process, and that using a mix of live avatars, non-player characters, and live sensor feeds (e.g. real time meteorology) can help visualization of the area of operations. Finally, tactical operations are improved via better collaboration and integration of real world sensing capabilities, and in most situations, 30 VWs improve the state of the art over current "dots on a map" 20 geospatial visualization. However, several capability gaps preclude a fuller realization of this vision. In this paper, we identify many of these gaps and suggest research directions

Robotics development for the enhancement of space endeavors

NASA Astrophysics Data System (ADS)

Mauceri, A. J.; Clarke, Margaret M.

Telerobotics and robotics development activities to support NASA's goal of increasing opportunities in space commercialization and exploration are described. The Rockwell International activities center is using robotics to improve efficiency and safety in three related areas: remote control of autonomous systems, automated nondestructive evaluation of aspects of vehicle integrity, and the use of robotics in space vehicle ground reprocessing operations. In the first area, autonomous robotic control, Rockwell is using the control architecture, NASREM, as the foundation for the high level command of robotic tasks. In the second area, we have demonstrated the use of nondestructive evaluation (using acoustic excitation and lasers sensors) to evaluate the integrity of space vehicle surface material bonds, using Orbiter 102 as the test case. In the third area, Rockwell is building an automated version of the present manual tool used for Space Shuttle surface tile re-waterproofing. The tool will be integrated into an orbiter processing robot being developed by a KSC-led team.

Role of data warehousing in healthcare epidemiology.

PubMed

Wyllie, D; Davies, J

2015-04-01

Electronic storage of healthcare data, including individual-level risk factors for both infectious and other diseases, is increasing. These data can be integrated at hospital, regional and national levels. Data sources that contain risk factor and outcome information for a wide range of conditions offer the potential for efficient epidemiological analysis of multiple diseases. Opportunities may also arise for monitoring healthcare processes. Integrating diverse data sources presents epidemiological, practical, and ethical challenges. For example, diagnostic criteria, outcome definitions, and ascertainment methods may differ across the data sources. Data volumes may be very large, requiring sophisticated computing technology. Given the large populations involved, perhaps the most challenging aspect is how informed consent can be obtained for the development of integrated databases, particularly when it is not easy to demonstrate their potential. In this article, we discuss some of the ups and downs of recent projects as well as the potential of data warehousing for antimicrobial resistance monitoring. Copyright © 2015. Published by Elsevier Ltd.

Authentic Instruction and Technology Literacy

ERIC Educational Resources Information Center

Cydis, Susan

2015-01-01

Technology integration is an important aspect of student competence in the 21st century. The use of technology in teaching and learning is a valuable practice for supporting student learning and engagement. Modelling the pedagogical practices that integrate authentic, performance-based opportunities for technology integration was the focus of a…

Translational Medicine Guide transforms drug development processes: the recent Merck experience.

PubMed

Dolgos, Hugues; Trusheim, Mark; Gross, Dietmar; Halle, Joern-Peter; Ogden, Janet; Osterwalder, Bruno; Sedman, Ewen; Rossetti, Luciano

2016-03-01

Merck is implementing a question-based Translational Medicine Guide (TxM Guide) beginning as early as lead optimization into its stage-gate drug development process. Initial experiences with the TxM Guide, which is embedded into an integrated development plan tailored to each development program, demonstrated opportunities to improve target understanding, dose setting (i.e., therapeutic index), and patient subpopulation selection with more robust and relevant early human-based evidence, and increased use of biomarkers and simulations. The TxM Guide is also helping improve organizational learning, costs, and governance. It has also shown the need for stronger external resources for validating biomarkers, demonstrating clinical utility, tracking natural disease history, and biobanking. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

Cooling the vertical surface by conditionally single pulses

NASA Astrophysics Data System (ADS)

Karpov, Pavel; Nazarov, Alexander; Serov, Anatoly; Terekhov, Victor

2017-10-01

You Sprays with periodic supply of the droplet phase have great opportunities to control the heat exchange processes. Varying pulse duration and frequency of their repetition, we can achieve the optimal conditions of evaporative cooling with minimization of the liquid flow rate. The paper presents experimental data on studying local heat transfer on a large subcooled surface, obtained on the original setup with multinozzle controlled system of impact irrigation by the gas-droplet flow. A contribution to intensification of the spray parameters (flow rate, pulse duration, repetition frequency) per a growth of integral heat transfer was studied. Data on instantaneous distribution of the heat flux value helped us to describe the processes occurring on the studied surface. These data could describe the regime of "island" film cooling.

Kingsbury Bay-Grassy Point habitat restoration project: A Health Impact Assessment-oral presentation

EPA Science Inventory

Undertaking large-scale aquatic habitat restoration projects in prominent waterfront locations, such as city parks, provides an opportunity to both improve ecological integrity and enhance community well-being. However, to consider both opportunities simultaneously, a community-b...

Implications of learning theory for developing programs to decrease overeating

PubMed Central

Boutelle, Kerri N.; Bouton, Mark E.

2015-01-01

Childhood obesity is associated with medical and psychological comorbidities, and interventions targeting overeating could be pragmatic and have a significant impact on weight. Calorically dense foods are easily available, variable, and tasty which allows for effective opportunities to learn to associate behaviors and cues in the environment with food through fundamental conditioning processes, resulting in measurable psychological and physiological food cue reactivity in vulnerable children. Basic research suggests that initial learning is difficult to erase, and that it is vulnerable to a number of phenomena that will allow the original learning to re-emerge after it is suppressed or replaced. These processes may help explain why it may be difficult to change food cue reactivity and overeating over the long term. Extinction theory may be used to develop effective cue-exposure treatments to decrease food cue reactivity through inhibitory learning, although these processes are complex and require an integral understanding of the theory and individual differences. Additionally, learning theory can be used to develop other interventions that may prove to be useful. Through an integration of learning theory, basic and translational research, it may be possible to develop interventions that can decrease the urges to overeat, and improve the weight status of children. PMID:25998235

Poly(A)-tag deep sequencing data processing to extract poly(A) sites.

PubMed

Wu, Xiaohui; Ji, Guoli; Li, Qingshun Quinn

2015-01-01

Polyadenylation [poly(A)] is an essential posttranscriptional processing step in the maturation of eukaryotic mRNA. The advent of next-generation sequencing (NGS) technology has offered feasible means to generate large-scale data and new opportunities for intensive study of polyadenylation, particularly deep sequencing of the transcriptome targeting the junction of 3'-UTR and the poly(A) tail of the transcript. To take advantage of this unprecedented amount of data, we present an automated workflow to identify polyadenylation sites by integrating NGS data cleaning, processing, mapping, normalizing, and clustering. In this pipeline, a series of Perl scripts are seamlessly integrated to iteratively map the single- or paired-end sequences to the reference genome. After mapping, the poly(A) tags (PATs) at the same genome coordinate are grouped into one cleavage site, and the internal priming artifacts removed. Then the ambiguous region is introduced to parse the genome annotation for cleavage site clustering. Finally, cleavage sites within a close range of 24 nucleotides and from different samples can be clustered into poly(A) clusters. This procedure could be used to identify thousands of reliable poly(A) clusters from millions of NGS sequences in different tissues or treatments.

Incorporating healthcare informatics into the strategic planning process in nursing education.

PubMed

Sackett, Kay; Jones, Janice; Erdley, W Scott

2005-01-01

The purpose of this article is to describe the incorporation of healthcare informatics into the strategic planning process in nursing education. An exemplar from the University at Buffalo, the State University of New York School of Nursing, is interwoven throughout the article. The challenges and successes inherent in a paradigm shift embracing the multifaceted adoption of technology in higher education are illustrated. The paradigm shift that necessitated this change, the need for informatics standards and competencies identified by regulatory agencies and the relationship of the triad mission of the Academy which includes research, teaching and service are then elucidated. Information pertinent to the strategic planning process is described including the use of a strengths, weaknesses, opportunities and threats (SWOT) analysis to facilitate the integration of a healthcare informatics model into a nursing curriculum.

Complex clinical reasoning in the critical care unit - difficulties, pitfalls and adaptive strategies.

PubMed

Shaw, M; Singh, S

2015-04-01

Diagnostic error has implications for both clinical outcome and resource utilisation, and may often be traced to impaired data gathering, processing or synthesis because of the influence of cognitive bias. Factors inherent to the intensive/acute care environment afford multiple additional opportunities for such errors to occur. This article illustrates many of these with reference to a case encountered on our intensive care unit. Strategies to improve completeness of data gathering, processing and synthesis in the acute care environment are critically appraised in the context of early detection and amelioration of cognitive bias. These include reflection, targeted simulation training and the integration of social media and IT based aids in complex diagnostic processes. A framework which can be quickly and easily employed in a variety of clinical environments is then presented. © 2015 John Wiley & Sons Ltd.

Quality cell therapy manufacturing by design.

PubMed

Lipsitz, Yonatan Y; Timmins, Nicholas E; Zandstra, Peter W

2016-04-01

Transplantation of live cells as therapeutic agents is poised to offer new treatment options for a wide range of acute and chronic diseases. However, the biological complexity of cells has hampered the translation of laboratory-scale experiments into industrial processes for reliable, cost-effective manufacturing of cell-based therapies. We argue here that a solution to this challenge is to design cell manufacturing processes according to quality-by-design (QbD) principles. QbD integrates scientific knowledge and risk analysis into manufacturing process development and is already being adopted by the biopharmaceutical industry. Many opportunities to incorporate QbD into cell therapy manufacturing exist, although further technology development is required for full implementation. Linking measurable molecular and cellular characteristics of a cell population to final product quality through QbD is a crucial step in realizing the potential for cell therapies to transform healthcare.

A perspective on the FAA approval process: Integrating rotorcraft displays, controls and workload

NASA Technical Reports Server (NTRS)

Green, David L.; Hart, Jake; Hwoschinsky, Peter

1993-01-01

The FAA is responsible for making the determination that a helicopter is safe for IFR operations in the National Airspace System (NAS). This involves objective and subjective evaluations of cockpit displays, flying qualities, procedures and human factors as they affect performance and workload. After all of the objective evaluations are completed, and all Federal Regulations have been met, FAA pilots make the final subjective judgement as to suitability for use by civil pilots in the NAS. The paper uses the flying qualities and pilot workload characteristics of a small helicopter to help examine the FAA pilot's involvement in this process. The result highlights the strengths of the process and its importance to the approval of new aircraft and equipments for civil IFR helicopter applications. The paper also identifies opportunities for improvement.

Fuel and power coproduction: The Liquid Phase Methanol (LPMEOH{trademark}) process demonstration at Kingsport

DOE Office of Scientific and Technical Information (OSTI.GOV)

Drown, D.P.; Brown, W.R.; Heydorn, E.C.

1997-12-31

The Liquid Phase Methanol (LPMEOH{trademark}) process uses a slurry bubble column reactor to convert syngas (primarily a mixture of carbon monoxide and hydrogen) to methanol. Because of its superior heat management, the process is able to be designed to directly handle the carbon monoxide (CO)-rich syngas characteristic of the gasification of coal, petroleum coke, residual oil, wastes, or of other hydrocarbon feedstocks. When added to an integrated gasification combined cycle (IGCC) power plant, the LPMEOH{trademark} process converts a portion of the CO-rich syngas produced by the gasifier to methanol, and the remainder of the unconverted gas is used to fuelmore » the gas turbine combined-cycle power plant. The LPMEOH{trademark} process has the flexibility to operate in a daily electricity demand load-following manner. Coproduction of power and methanol via IGCC and the LPMEOH{trademark} process provides opportunities for energy storage for electrical demand peak shaving, clean fuel for export, and/or chemical methanol sales.« less

NASA UAS Integration Efforts

NASA Technical Reports Server (NTRS)

Hackenberg, Davis

2017-01-01

This is a benefit to NASA because of all the networking opportunities as well as sharing information about UAS-NAS within the UAS community. NASA has developed, and is executing, a Cohesive Strategy for UAS Integration

Sustainability in primary care and Mental Health Integration projects in Veterans Health Administration.

PubMed

Ford, James H; Krahn, Dean; Oliver, Karen Anderson; Kirchner, JoAnn

2012-01-01

To explore staff perceptions about sustainability, commitment to change, participation in change process, and information received about the change project within the Veterans Administration Primary Care and Mental Health Integration (PC-MHI) initiative and to examine differences from the Veterans Health Administration Mental Health Systems Redesign (MHSR) initiative. Surveys of change team members involved in the Veterans Affairs PC-MHI and MHSR initiatives. One-way analysis of variance examined the relationship between commitment, participation and information, and sustainability. Differences in PC-MHI sustainability were explored by location and job classification. Staff sustainability perceptions were compared with MHSR results. Sustainability differed by staff discipline. Difference between MHSR and PC-MHI existed by job function and perceptions about the change benefits. Participation in the change process and information received about the change process were positively correlated with sustainability. Staff commitment to change was positively associated with staff perceptions about the benefits of change and staff attitudes toward change. Sustainability is an important part of organizational change efforts. Change complexity seems to influence perception about sustainability and impacts staff perceptions about the benefits of change. These perceptions seem to be driven by the information received and opportunities to participate in the change process. Further research is needed to understand how information and participation influence sustainability and affect employee commitment to change.

The Paralympic Movement: using sports to promote health, disability rights, and social integration for athletes with disabilities.

PubMed

Blauwet, Cheri; Willick, Stuart E

2012-11-01

Competitive sports for people with disabilities has grown rapidly over the past several decades, and opportunities for participation are increasingly available throughout the spectrum from developmental to elite. The Paralympic Games, seen as the pinnacle sporting event that represents the broader Paralympic Movement, has provided a platform to showcase the abilities of people with disabilities while also serving as a catalyst for disability rights through ensuring integration, equality of opportunity, and accessibility of the built environment. Concurrently, media coverage of the Paralympic Games has led to an increased awareness of opportunities for sport participation for individuals with disabilities and, with it, the adjustment of norms regarding expectations for exercise as a component of preventive health. In addition, there is evidence of the power of sports to stimulate confidence, self-efficacy, and a self-perceived high quality of life for individuals with disabilities above and beyond the basic benefits to cardiometabolic fitness. When taken together, the promotion of health, disability rights, and social integration through sports has the power to transform the lives of those who participate and to further stimulate the expansion of opportunities available to the next generation of athletes with disabilities. Copyright © 2012 American Academy of Physical Medicine and Rehabilitation. Published by Elsevier Inc. All rights reserved.

Social support, social integration, and inflammatory cytokines: A meta-analysis.

PubMed

Uchino, Bert N; Trettevik, Ryan; Kent de Grey, Robert G; Cronan, Sierra; Hogan, Jasara; Baucom, Brian R W

2018-05-01

Social support and social integration have been linked to lower rates of morbidity and mortality. However, the biological mechanisms responsible for such links need greater attention to advance theory and unique intervention opportunities. The main aim of this article was to conduct a meta-analytic review of the association between social support-social integration and inflammatory cytokines (e.g., interleukin-6, C-reactive protein) and test several proposed moderators from prior qualitative reviews. A literature search was conducted using the ancestry approach and with databases PsycINFO, Medline, and EMBASE by crossing the exact keywords social support or social integration with inflammation . The review identified 41 studies with a total of 73,037 participants. The omnibus meta-analysis showed that social support-social integration were significantly related to lower levels of inflammation (Zr = -.073). These results were not moderated by the operationalization of social relationships or the type of population, cytokine, and design. These data suggest that inflammation is at least one important biological mechanism linking social support and social integration to the development and course of disease. Future work should continue to build on this review and address next-generation questions regarding antecedent processes, mechanisms, and other potential moderators. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

Transfer printing techniques for materials assembly and micro/nanodevice fabrication.

PubMed

Carlson, Andrew; Bowen, Audrey M; Huang, Yonggang; Nuzzo, Ralph G; Rogers, John A

2012-10-09

Transfer printing represents a set of techniques for deterministic assembly of micro-and nanomaterials into spatially organized, functional arrangements with two and three-dimensional layouts. Such processes provide versatile routes not only to test structures and vehicles for scientific studies but also to high-performance, heterogeneously integrated functional systems, including those in flexible electronics, three-dimensional and/or curvilinear optoelectronics, and bio-integrated sensing and therapeutic devices. This article summarizes recent advances in a variety of transfer printing techniques, ranging from the mechanics and materials aspects that govern their operation to engineering features of their use in systems with varying levels of complexity. A concluding section presents perspectives on opportunities for basic and applied research, and on emerging use of these methods in high throughput, industrial-scale manufacturing. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Exploring MEDLINE Space with Random Indexing and Pathfinder Networks

PubMed Central

Cohen, Trevor

2008-01-01

The integration of disparate research domains is a prerequisite for the success of the translational science initiative. MEDLINE abstracts contain content from a broad range of disciplines, presenting an opportunity for the development of methods able to integrate the knowledge they contain. Latent Semantic Analysis (LSA) and related methods learn human-like associations between terms from unannotated text. However, their computational and memory demands limits their ability to address a corpus of this size. Furthermore, visualization methods previously used in conjunction with LSA have limited ability to define the local structure of the associative networks LSA learns. This paper explores these issues by (1) processing the entire MEDLINE corpus using Random Indexing, a variant of LSA, and (2) exploring learned associations using Pathfinder Networks. Meaningful associations are inferred from MEDLINE, including a drug-disease association undetected by PUBMED search. PMID:18999236

Exploring MEDLINE space with random indexing and pathfinder networks.

PubMed

Cohen, Trevor

2008-11-06

The integration of disparate research domains is a prerequisite for the success of the translational science initiative. MEDLINE abstracts contain content from a broad range of disciplines, presenting an opportunity for the development of methods able to integrate the knowledge they contain. Latent Semantic Analysis (LSA) and related methods learn human-like associations between terms from unannotated text. However, their computational and memory demands limits their ability to address a corpus of this size. Furthermore, visualization methods previously used in conjunction with LSA have limited ability to define the local structure of the associative networks LSA learns. This paper explores these issues by (1) processing the entire MEDLINE corpus using Random Indexing, a variant of LSA, and (2) exploring learned associations using Pathfinder Networks. Meaningful associations are inferred from MEDLINE, including a drug-disease association undetected by PUBMED search.

Smart textiles: Challenges and opportunities

NASA Astrophysics Data System (ADS)

Cherenack, Kunigunde; van Pieterson, Liesbeth

2012-11-01

Smart textiles research represents a new model for generating creative and novel solutions for integrating electronics into unusual environments and will result in new discoveries that push the boundaries of science forward. A key driver for smart textiles research is the fact that both textile and electronics fabrication processes are capable of functionalizing large-area surfaces at very high speeds. In this article we review the history of smart textiles development, introducing the main trends and technological challenges faced in this field. Then, we identify key challenges that are the focus of ongoing research. We then proceed to discuss fundamentals of smart textiles: textile fabrication methods and textile interconnect lines, textile sensor, and output device components and integration of commercial components into textile architectures. Next we discuss representative smart textile systems and finally provide our outlook over the field and a prediction for the future.

Anatomy teaching assistants: facilitating teaching skills for medical students through apprenticeship and mentoring.

PubMed

Lachman, Nirusha; Christensen, Kevin N; Pawlina, Wojciech

2013-01-01

Significant increase in the literature regarding "residents as teachers" highlights the importance of providing opportunities and implementing guidelines for continuing medical education and professional growth. While most medical students are enthusiastic about their future role as resident-educators, both students and residents feel uncomfortable teaching their peers due to the lack of necessary skills. However, whilst limited and perhaps only available to select individuals, opportunities for developing good teaching practice do exist and may be identified in courses that offer basic sciences. The Department of Anatomy, College of Medicine, Mayo Clinic offers a teaching assistant (TA) elective experience to third- and fourth-year medical students through integrated apprenticeship and mentoring during the human structure didactic block. This article, aims to describe a curriculum for a TA elective within the framework of a basic science course through mentoring and apprenticeship. Opportunities for medical students to become TAs, process of TAs' recruitment, mentoring and facilitation of teaching and education research skills, a method for providing feedback and debriefing are described. Developing teaching practice based on apprenticeship and mentoring lends to more accountability to both TA's and course faculty by incorporating universal competencies to facilitate the TA experience.

Partitioning in aqueous two-phase systems: Analysis of strengths, weaknesses, opportunities and threats.

PubMed

Soares, Ruben R G; Azevedo, Ana M; Van Alstine, James M; Aires-Barros, M Raquel

2015-08-01

For half a century aqueous two-phase systems (ATPSs) have been applied for the extraction and purification of biomolecules. In spite of their simplicity, selectivity, and relatively low cost they have not been significantly employed for industrial scale bioprocessing. Recently their ability to be readily scaled and interface easily in single-use, flexible biomanufacturing has led to industrial re-evaluation of ATPSs. The purpose of this review is to perform a SWOT analysis that includes a discussion of: (i) strengths of ATPS partitioning as an effective and simple platform for biomolecule purification; (ii) weaknesses of ATPS partitioning in regard to intrinsic problems and possible solutions; (iii) opportunities related to biotechnological challenges that ATPS partitioning may solve; and (iv) threats related to alternative techniques that may compete with ATPS in performance, economic benefits, scale up and reliability. This approach provides insight into the current status of ATPS as a bioprocessing technique and it can be concluded that most of the perceived weakness towards industrial implementation have now been largely overcome, thus paving the way for opportunities in fermentation feed clarification, integration in multi-stage operations and in single-step purification processes. Copyright © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Implications of pleiotropy: challenges and opportunities for mining Big Data in biomedicine.

PubMed

Yang, Can; Li, Cong; Wang, Qian; Chung, Dongjun; Zhao, Hongyu

2015-01-01

Pleiotropy arises when a locus influences multiple traits. Rich GWAS findings of various traits in the past decade reveal many examples of this phenomenon, suggesting the wide existence of pleiotropic effects. What underlies this phenomenon is the biological connection among seemingly unrelated traits/diseases. Characterizing the molecular mechanisms of pleiotropy not only helps to explain the relationship between diseases, but may also contribute to novel insights concerning the pathological mechanism of each specific disease, leading to better disease prevention, diagnosis and treatment. However, most pleiotropic effects remain elusive because their functional roles have not been systematically examined. A systematic investigation requires availability of qualified measurements at multilayered biological processes (e.g., transcription and translation). The rise of Big Data in biomedicine, such as high-quality multi-omics data, biomedical imaging data and electronic medical records of patients, offers us an unprecedented opportunity to investigate pleiotropy. There will be a great need of computationally efficient and statistically rigorous methods for integrative analysis of these Big Data in biomedicine. In this review, we outline many opportunities and challenges in methodology developments for systematic analysis of pleiotropy, and highlight its implications on disease prevention, diagnosis and treatment.

When Opportunity Knocks: Integrating Language Arts and the Daily Calendar

ERIC Educational Resources Information Center

Biddle, Melissa

2007-01-01

With daily classroom schedules jammed with many concepts and skills to cover, integrating subjects whenever possible offers some relief. Primary classrooms can use their daily calendar time to integrate language arts and math. This teaching approach includes the use of word walls, interactive writing, journaling, and other effective teaching…

About My Father's Work: A Vehicle for the Integration of Catholic Values.

ERIC Educational Resources Information Center

Krebbs, Mary Jane

2001-01-01

Asserts that it is time to formalize the practices involved in integrating values into Catholic education. Presents the six-step Educational Community Opportunity for Stewardship (ECOS) system and the Catholic Education Community manual as vital components in preparing teachers for values integration. Presents conceptual and organizational…

Learning from deaths: Parents' Active Role and ENgagement in The review of their Stillbirth/perinatal death (the PARENTS 1 study).

PubMed

Bakhbakhi, Danya; Siassakos, Dimitrios; Burden, Christy; Jones, Ffion; Yoward, Freya; Redshaw, Maggie; Murphy, Samantha; Storey, Claire

2017-10-02

Following a perinatal death, a formal standardised multi-disciplinary review should take place, to learn from the death of a baby and facilitate improvements in future care. It has been recommended that bereaved parents should be offered the opportunity to give feedback on the care they have received and integrate this feedback into the perinatal mortality review process. However, the MBRRACE-UK Perinatal Confidential Enquiry (2015) found that only one in 20 cases parental concerns were included in the review. Although guidance suggests parental opinion should be sought, little evidence exists on how this may be incorporated into the perinatal mortality review process. The purpose of the PARENTS study was to investigate bereaved parents' views on involvement in the perinatal mortality review process. A semi-structured focus group of 11 bereaved parents was conducted in South West England. A purposive sampling technique was utilised to recruit a diverse sample of women and their partners who had experienced a perinatal death more than 6 months prior to the study. A six-stage thematic analysis was followed to explore parental perceptions and expectations of the perinatal mortality review process. Four over-arching themes emerged from the analysis: transparency; flexibility combined with specificity; inclusivity; and a positive approach. It was evident that the majority of parents were supportive of their involvement in the perinatal mortality review process and they wanted to know the outcome of the meeting. It emerged that an individualised approach should be taken to allow flexibility on when and how they could contribute to the process. The emotional aspects of care should be considered as well as the clinical care. Parents identified that the whole care pathway should be examined during the review including antenatal, postnatal, and neonatal and community based care. They agreed that there should be an opportunity for parents to give feedback on both good and poor aspects of their care. Parents were unaware that a review of their baby's death took place in the hospital. Parental involvement in the perinatal mortality review process would promote an open culture in the healthcare system and learning from adverse events including deaths. Further research should focus on designing and evaluating a perinatal mortality review process where parental feedback will be integral.

An online spatial database of Australian Indigenous Biocultural Knowledge for contemporary natural and cultural resource management.

PubMed

Pert, Petina L; Ens, Emilie J; Locke, John; Clarke, Philip A; Packer, Joanne M; Turpin, Gerry

2015-11-15

With growing international calls for the enhanced involvement of Indigenous peoples and their biocultural knowledge in managing conservation and the sustainable use of physical environment, it is timely to review the available literature and develop cross-cultural approaches to the management of biocultural resources. Online spatial databases are becoming common tools for educating land managers about Indigenous Biocultural Knowledge (IBK), specifically to raise a broad awareness of issues, identify knowledge gaps and opportunities, and to promote collaboration. Here we describe a novel approach to the application of internet and spatial analysis tools that provide an overview of publically available documented Australian IBK (AIBK) and outline the processes used to develop the online resource. By funding an AIBK working group, the Australian Centre for Ecological Analysis and Synthesis (ACEAS) provided a unique opportunity to bring together cross-cultural, cross-disciplinary and trans-organizational contributors who developed these resources. Without such an intentionally collaborative process, this unique tool would not have been developed. The tool developed through this process is derived from a spatial and temporal literature review, case studies and a compilation of methods, as well as other relevant AIBK papers. The online resource illustrates the depth and breadth of documented IBK and identifies opportunities for further work, partnerships and investment for the benefit of not only Indigenous Australians, but all Australians. The database currently includes links to over 1500 publically available IBK documents, of which 568 are geo-referenced and were mapped. It is anticipated that as awareness of the online resource grows, more documents will be provided through the website to build the database. It is envisaged that this will become a well-used tool, integral to future natural and cultural resource management and maintenance. Copyright © 2015. Published by Elsevier B.V.

Community health workers and the Patient Protection and Affordable Care Act: an opportunity for a research, advocacy, and policy agenda.

PubMed

Shah, Megha K; Heisler, Michele; Davis, Matthew M

2014-02-01

Community health workers (CHWs), who have been shown to be effective in multiple roles in the provision of culturally appropriate health care in a variety of settings, have the potential to be important members of an interdisciplinary health care team. Recent efforts have started to explore how best to integrate CHWs into the health system. However, to date, there has been limited policy guidance, support, or evidence on how best to achieve this on a larger scale. The Patient Protection and Affordable Care Act (ACA), through several provisions, provides a unique opportunity to create a unified framework for workforce integration and wider utilization of CHWs. This review identifies four major opportunities to further the research, advocacy, and policy agenda for CHWs.

The controlled growth of perovskite thin films: Opportunities, challenges, and synthesis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schlom, D.G.; Theis, C.D.; Hawley, M.E.

1997-10-01

The broad spectrum of electronic and optical properties exhibited by perovskites offers tremendous opportunities for microelectronic devices, especially when a combination of properties in a single device is desired. Molecular beam epitaxy (MBE) has achieved unparalleled control in the integration of semiconductors at the monolayer-level; its use for the integration of perovskites with similar nanoscale customization appears promising. Composition control and oxidation are often significant challenges to the growth of perovskites by MBE, but we show that these can be met through the use of purified ozone as an oxidant and real-time atomic absorption composition control. The opportunities, challenges, andmore » synthesis of oxide heterostructures by reactive MBE are described, with examples taken from the growth of oxide superconductors and oxide ferroelectrics.« less

Opportunities for faculty-librarian collaboration in an expanded dentistry curriculum.

PubMed

Stone, Sean; Quirke, Michelle; Lowe, M Sara

2018-06-01

With the increased emphasis on evidence based practice, developing information literacy skills earlier in health care education programmes is widely accepted. However finding opportunities for relevant teaching can present challenges, often leading to a lack of integration. In this paper, guest writers Sean Stone and colleagues from Indiana University discuss their involvement with an expanded dental hygiene curriculum in the University School of Dentistry. This expansion has provided the opportunity to plan integration of information and oral health literacy instruction and evidence based practice across the new curriculum, and provide transferable skills for any major. In particular, the paper addresses the developmental work the health librarian team engaged in from course design, delivery and assessment to improve student preparedness for evidence based practice. H.S. © 2018 Health Libraries Group.

Additional Crime Scenes for Projectile Motion Unit

ERIC Educational Resources Information Center

Fullerton, Dan; Bonner, David

2011-01-01

Building students' ability to transfer physics fundamentals to real-world applications establishes a deeper understanding of underlying concepts while enhancing student interest. Forensic science offers a great opportunity for students to apply physics to highly engaging, real-world contexts. Integrating these opportunities into inquiry-based…

Second-Language Literacy, Immigration, and Globalization

ERIC Educational Resources Information Center

Soto Huerta, M. E.; Pérez, B.

2015-01-01

Second language literacy development is a significant factor influencing immigrants' opportunities to integrate with the host society. To examine the opportunities that different immigrant groups have had for obtaining both, we selected four published studies that had been originally analyzed through a sociocultural perspective, a prominent…

Colloquium paper: three ambitious (and rather unorthodox) assignments for the field of biodiversity genetics.

PubMed

Avise, John C

2008-08-12

The field of molecular genetics has many roles in biodiversity assessment and conservation. I summarize three of those standard roles and propose logical extensions of each. First, many biologists suppose that a comprehensive picture of the Tree of Life will soon emerge from multilocus DNA sequence data interpreted in concert with fossils and other evidence. If nonreticulate trees are indeed valid metaphors for life's history, then a well dated global phylogeny will offer an opportunity to erect a universally standardized scheme of biological classification. If life's history proves to be somewhat reticulate, a web-like phylogenetic pattern should become evident and will offer opportunities to reevaluate the fundamental nature of evolutionary processes. Second, extensive networks of wildlife sanctuaries offer some hope for shepherding appreciable biodiversity through the ongoing extinction crisis, and molecular genetics can assist in park design by helping to identify key species, historically important biotic areas, and biodiversity hotspots. An opportunity centers on the concept of Pleistocene Parks that could protect "legacy biotas" in much the same way that traditional national parks preserve special geological features and historical landmarks honor legacy events in human affairs. Third, genetic perspectives have become an integral part of many focused conservation efforts by unveiling ecological, behavioral, or evolutionary phenomena relevant to population management. They also can open opportunities to educate the public about the many intellectual gifts and aesthetic marvels of the natural world.

Three ambitious (and rather unorthodox) assignments for the field of biodiversity genetics

PubMed Central

Avise, John C.

2008-01-01

The field of molecular genetics has many roles in biodiversity assessment and conservation. I summarize three of those standard roles and propose logical extensions of each. First, many biologists suppose that a comprehensive picture of the Tree of Life will soon emerge from multilocus DNA sequence data interpreted in concert with fossils and other evidence. If nonreticulate trees are indeed valid metaphors for life's history, then a well dated global phylogeny will offer an opportunity to erect a universally standardized scheme of biological classification. If life's history proves to be somewhat reticulate, a web-like phylogenetic pattern should become evident and will offer opportunities to reevaluate the fundamental nature of evolutionary processes. Second, extensive networks of wildlife sanctuaries offer some hope for shepherding appreciable biodiversity through the ongoing extinction crisis, and molecular genetics can assist in park design by helping to identify key species, historically important biotic areas, and biodiversity hotspots. An opportunity centers on the concept of Pleistocene Parks that could protect “legacy biotas” in much the same way that traditional national parks preserve special geological features and historical landmarks honor legacy events in human affairs. Third, genetic perspectives have become an integral part of many focused conservation efforts by unveiling ecological, behavioral, or evolutionary phenomena relevant to population management. They also can open opportunities to educate the public about the many intellectual gifts and aesthetic marvels of the natural world. PMID:18695224

Advancing the practice of health impact assessment in Canada: Obstacles and opportunities

DOE Office of Scientific and Technical Information (OSTI.GOV)

McCallum, Lindsay C., E-mail: lindsay.mccallum@mail.utoronto.ca; Intrinsik Environmental Sciences Inc., 6605 Hurontario Street, Mississauga, Ontario L5T0A3; Ollson, Christopher A., E-mail: collson@intrinsik.com

Health Impact Assessment (HIA) is recognized as a useful tool that can identify potential health impacts resulting from projects or policy initiatives. Although HIA has become an established practice in some countries, it is not yet an established practice in Canada. In order to enable broader support for HIA, this study provides a comprehensive review and analysis of the peer-reviewed and gray literature on the state of HIA practice. The results of this review revealed that, although there is an abundance of publications relating to HIA, there remains a lack of transparent, consistent and reproducible approaches and methods throughout themore » process. Findings indicate a need for further research and development on a number of fronts, including: 1) the nature of HIA triggers; 2) consistent scoping and stakeholder engagement approaches; 3) use of evidence and transparency of decision-making; 4) reproducibility of assessment methods; 5) monitoring and evaluation protocols; and, 6) integration within existing regulatory frameworks. Addressing these issues will aid in advancing the more widespread use of HIA in Canada. - Highlights: • Reviewed current state of practice in the field of HIA • Identified key obstacles and opportunities for HIA advancement • Major issues include lack of consistent approach and methodology. • No national regulatory driver hinders opportunity for widespread use of HIA. • Identified research opportunities vital to developing HIA practice in Canada.« less

Additive Manufacturing of Silicon Carbide-Based Ceramic Matrix Composites: Technical Challenges and Opportunities

NASA Technical Reports Server (NTRS)

Singh, Mrityunjay; Halbig, Michael C.; Grady, Joseph E.

2016-01-01

Advanced SiC-based ceramic matrix composites offer significant contributions toward reducing fuel burn and emissions by enabling high overall pressure ratio (OPR) of gas turbine engines and reducing or eliminating cooling air in the hot-section components, such as shrouds, combustor liners, vanes, and blades. Additive manufacturing (AM), which allows high value, custom designed parts layer by layer, has been demonstrated for metals and polymer matrix composites. However, there has been limited activity on additive manufacturing of ceramic matrix composites (CMCs). In this presentation, laminated object manufacturing (LOM), binder jet process, and 3-D printing approaches for developing ceramic composite materials are presented. For the laminated object manufacturing (LOM), fiber prepreg laminates were cut into shape with a laser and stacked to form the desired part followed by high temperature heat treatments. For the binder jet, processing optimization was pursued through silicon carbide powder blending, infiltration with and without SiC nano powder loading, and integration of fibers into the powder bed. Scanning electron microscopy was conducted along with XRD, TGA, and mechanical testing. Various technical challenges and opportunities for additive manufacturing of ceramics and CMCs will be presented.

Constraints and Opportunities in GCM Model Development

NASA Technical Reports Server (NTRS)

Schmidt, Gavin; Clune, Thomas

2010-01-01

Over the past 30 years climate models have evolved from relatively simple representations of a few atmospheric processes to complex multi-disciplinary system models which incorporate physics from bottom of the ocean to the mesopause and are used for seasonal to multi-million year timescales. Computer infrastructure over that period has gone from punchcard mainframes to modern parallel clusters. Constraints of working within an ever evolving research code mean that most software changes must be incremental so as not to disrupt scientific throughput. Unfortunately, programming methodologies have generally not kept pace with these challenges, and existing implementations now present a heavy and growing burden on further model development as well as limiting flexibility and reliability. Opportunely, advances in software engineering from other disciplines (e.g. the commercial software industry) as well as new generations of powerful development tools can be incorporated by the model developers to incrementally and systematically improve underlying implementations and reverse the long term trend of increasing development overhead. However, these methodologies cannot be applied blindly, but rather must be carefully tailored to the unique characteristics of scientific software development. We will discuss the need for close integration of software engineers and climate scientists to find the optimal processes for climate modeling.

Techno-economic evaluation of 2nd generation bioethanol production from sugar cane bagasse and leaves integrated with the sugar-based ethanol process

PubMed Central

2012-01-01

Background Bioethanol produced from the lignocellulosic fractions of sugar cane (bagasse and leaves), i.e. second generation (2G) bioethanol, has a promising market potential as an automotive fuel; however, the process is still under investigation on pilot/demonstration scale. From a process perspective, improvements in plant design can lower the production cost, providing better profitability and competitiveness if the conversion of the whole sugar cane is considered. Simulations have been performed with AspenPlus to investigate how process integration can affect the minimum ethanol selling price of this 2G process (MESP-2G), as well as improve the plant energy efficiency. This is achieved by integrating the well-established sucrose-to-bioethanol process with the enzymatic process for lignocellulosic materials. Bagasse and leaves were steam pretreated using H3PO4 as catalyst and separately hydrolysed and fermented. Results The addition of a steam dryer, doubling of the enzyme dosage in enzymatic hydrolysis, including leaves as raw material in the 2G process, heat integration and the use of more energy-efficient equipment led to a 37 % reduction in MESP-2G compared to the Base case. Modelling showed that the MESP for 2G ethanol was 0.97 US$/L, while in the future it could be reduced to 0.78 US$/L. In this case the overall production cost of 1G + 2G ethanol would be about 0.40 US$/L with an output of 102 L/ton dry sugar cane including 50 % leaves. Sensitivity analysis of the future scenario showed that a 50 % decrease in the cost of enzymes, electricity or leaves would lower the MESP-2G by about 20%, 10% and 4.5%, respectively. Conclusions According to the simulations, the production of 2G bioethanol from sugar cane bagasse and leaves in Brazil is already competitive (without subsidies) with 1G starch-based bioethanol production in Europe. Moreover 2G bioethanol could be produced at a lower cost if subsidies were used to compensate for the opportunity cost from the sale of excess electricity and if the cost of enzymes continues to fall. PMID:22502801

Perceptions of Black Parents in an Undesegregated Subdistrict of an Integrated School System

ERIC Educational Resources Information Center

Sobol, Marion G.; Beck, William W.

1978-01-01

A majority of parents whose children attended segregated schools in a court-ordered integrated school system felt that mixed schools offer better educational opportunities than do segregated schools. (Author)

Improving integration and coordination of funding, technical assistance, and reporting/data collection: recommendations from CDC and USAPI stakeholders.

PubMed

Ka'opua, Lana Sue I; White, Susan F; Rochester, Phyllis F; Holden, Debra J

2010-09-01

Current US Federal funding mechanisms may foster program silos that disable sharing of resources and information across programs within a larger system of public health services. Such silos present challenges to USAPI communities where human resources, health infrastructure, and health financing are limited. Integrative and coordinated approaches have been recommended. The CDC Pacific Islands Integration and Coordination project was initiated by the Division of Cancer Prevention and Control (DCPC). Its project aim was to identify ways for the CDC to collaborate with the USAPI in improving CDC activities and processes related to chronic disease. This article focuses on recommendations for improving coordination and integration in three core areas of health services programming: funding, program reporting/data collection and analysis, and technical assistance. Preliminary information on challenges and issues relevant to the core areas was gathered through site visits, focus groups, key informant interviews, and other sources. This information was used by stakeholder groups from the CDC and the USAPI to develop recommendations in the core programming areas. Recommendations generated at the CDC and USAPI stakeholder meetings were prepared into a single set of recommendations and stakeholders reviewed the document for accuracy prior to its dissemination to CDC's National Center for Chronic Disease Prevention and Health Promotion programs management and staff. Key recommendations, include: (1) consideration of resource s and other challenges unique to the USAPI when reviewing funding applications, (2) consideration of ways to increase flexibility in USAPI use of program funds, (3) dedicate funding and human resources for technical assistance, (4) provide opportunities for capacity-building across programs and jurisdictions, (5) consider ways to more directly link program reporting with technical assistance. This project provided a unique opportunity for CDC and USAPI stakeholders to share diverse perspectives on challenges to public health programs in the USAPI. Despite diverse experiences, the final set of recommendations reflected a high level of concordance between USAPI and CDC stakeholders on ways to improve coordination and integration of CDC processes and activities in the three core areas. Recommendations have informed some actions already initiated by the DCPC, including the dedication of funds for leadership institutes aimed at enhancing USAPI capacity for sustainable, integrated regional and jurisdictional cancer control infrastructure. Such efforts are an important beginning, but more remains to be done. Indicated is the need for continuous dialogue and collaboration. While this project focused on the USAPI, our results may be relevant to those interested in inter-organizational collaborations, medically underserved areas, public health services programs, and community-based participatory approaches.

Integrate oral communication with technical writing: Towards a rationale

NASA Technical Reports Server (NTRS)

Skelton, T.

1981-01-01

Integrating oral communication and technical writing instruction, to give students the opportunity to learn and practice interpersonal skills, is proposed. By linking speech and writing the importance of small-group interaction in developing transferrable ideas is acknowledged. Three reasons for integration are examined: workday activities, application of role-taking to writing, and conflict resolution. Four advantages of integration are stated.

Natural search algorithms as a bridge between organisms, evolution, and ecology

PubMed Central

Hein, Andrew M.; Carrara, Francesco; Brumley, Douglas R.; Stocker, Roman; Levin, Simon A.

2016-01-01

The ability to navigate is a hallmark of living systems, from single cells to higher animals. Searching for targets, such as food or mates in particular, is one of the fundamental navigational tasks many organisms must execute to survive and reproduce. Here, we argue that a recent surge of studies of the proximate mechanisms that underlie search behavior offers a new opportunity to integrate the biophysics and neuroscience of sensory systems with ecological and evolutionary processes, closing a feedback loop that promises exciting new avenues of scientific exploration at the frontier of systems biology. PMID:27496324

Incorporating scenario-based simulation into a hospital nursing education program.

PubMed

Nagle, Beth M; McHale, Jeanne M; Alexander, Gail A; French, Brian M

2009-01-01

Nurse educators are challenged to provide meaningful and effective learning opportunities for both new and experienced nurses. Simulation as a teaching and learning methodology is being embraced by nursing in academic and practice settings to provide innovative educational experiences to assess and develop clinical competency, promote teamwork, and improve care processes. This article provides an overview of the historical basis for using simulation in education, simulation methodologies, and perceived advantages and disadvantages. It also provides a description of the integration of scenario-based programs using a full-scale patient simulator into nursing education programming at a large academic medical center.

The Emergency Department: Challenges and Opportunities for Suicide Prevention.

PubMed

Asarnow, Joan Rosenbaum; Babeva, Kalina; Horstmann, Elizabeth

2017-10-01

Emergency departments (EDs) can offer life-saving suicide prevention care. This article focuses on the ED and emergency services as service delivery sites for suicide prevention. Characteristics of EDs, models of emergency care, ED screening and brief intervention models, and practice guidelines and parameters are reviewed. A care process model for youths at risk for suicide and self-harm is presented, with guidance for clinicians based on the scientific evidence. Strengthening emergency infrastructure and integrating effective suicide prevention strategies derived from scientific research are critical for advancing suicide prevention objectives. Copyright © 2017 Elsevier Inc. All rights reserved.

Research and technology, 1993. Salute to Skylab and Spacelab: Two decades of discovery

NASA Technical Reports Server (NTRS)

1993-01-01

A summary description of Skylab and Spacelab is presented. The section on Advanced Studies includes projects in space science, space systems, commercial use of space, and transportation systems. Within the Research Programs area, programs are listed under earth systems science, space physics, astrophysics, and microgravity science and applications. Technology Programs include avionics, materials and manufacturing processes, mission operations, propellant and fluid management, structures and dynamics, and systems analysis and integration. Technology transfer opportunities and success are briefly described. A glossary of abbreviations and acronyms is appended as is a list of contract personnel within the program areas.

A scale-based approach to interdisciplinary research and expertise in sports.

PubMed

Ibáñez-Gijón, Jorge; Buekers, Martinus; Morice, Antoine; Rao, Guillaume; Mascret, Nicolas; Laurin, Jérome; Montagne, Gilles

2017-02-01

After more than 20 years since the introduction of ecological and dynamical approaches in sports research, their promising opportunity for interdisciplinary research has not been fulfilled yet. The complexity of the research process and the theoretical and empirical difficulties associated with an integrated ecological-dynamical approach have been the major factors hindering the generalisation of interdisciplinary projects in sports sciences. To facilitate this generalisation, we integrate the major concepts from the ecological and dynamical approaches to study behaviour as a multi-scale process. Our integration gravitates around the distinction between functional (ecological) and execution (organic) scales, and their reciprocal intra- and inter-scale constraints. We propose an (epistemological) scale-based definition of constraints that accounts for the concept of synergies as emergent coordinative structures. To illustrate how we can operationalise the notion of multi-scale synergies we use an interdisciplinary model of locomotor pointing. To conclude, we show the value of this approach for interdisciplinary research in sport sciences, as we discuss two examples of task-specific dimensionality reduction techniques in the context of an ongoing project that aims to unveil the determinants of expertise in basketball free throw shooting. These techniques provide relevant empirical evidence to help bootstrap the challenging modelling efforts required in sport sciences.

Factors impacting participation of European elite deaf athletes in sport.

PubMed

Kurková, Petra; Válková, Hana; Scheetz, Nanci

2011-03-01

This study examine 53 European elite deaf athletes for their family's hearing status, use of hearing aids, communication preference, education in integrated or segregated settings, family members' encouragement for participation in sports, coach preference (hearing or deaf), and conditions for competitive events with deaf or hearing athletes. These data were gathered through semi-structured interviews administered in the athlete's native language. Deaf athletes reported that when given the opportunity to compete with hearing athletes, it enhanced their opportunity for competition. Participating in sports with hearing athletes played an important role in the integration of deaf athletes into mainstream society. If adaptations to communication can be made in these integrated settings, the ability of deaf athletes to participate in such settings will increase.

Administrative Challenges to the Integration of Oral Health With Primary Care: A SWOT Analysis of Health Care Executives at Federally Qualified Health Centers.

PubMed

Norwood, Connor W; Maxey, Hannah L; Randolph, Courtney; Gano, Laura; Kochhar, Komal

Inadequate access to preventive oral health services contributes to oral health disparities and is a major public health concern in the United States. Federally Qualified Health Centers play a critical role in improving access to care for populations affected by oral health disparities but face a number of administrative challenges associated with implementation of oral health integration models. We conducted a SWOT (strengths, weaknesses, opportunities, and threats) analysis with health care executives to identify strengths, weaknesses, opportunities, and threats of successful oral health integration in Federally Qualified Health Centers. Four themes were identified: (1) culture of health care organizations; (2) operations and administration; (3) finance; and (4) workforce.

Faculty Views on eTextbooks: A Narrative Study

ERIC Educational Resources Information Center

Bossaller, Jenny; Kammer, Jenna

2014-01-01

eTextbooks are both texts and tools. They provide opportunities for textbook companies to expand their services. Some large textbook companies are offering extensive educational technology products and services along with texts. These etexts, integrated into the Learning Management System (LMS), give instructors opportunities to use integrated…

Gendered Barriers to Educational Opportunities: Resettlement of Sudanese Refugees in Australia

ERIC Educational Resources Information Center

Hatoss, Aniko; Huijser, Henk

2010-01-01

This paper argues that whilst equitable educational pathways are integrated into educational policy discourses in Australia, there are significant gendered barriers to educational participation among members of the Sudanese refugee groups. The specific conditions of forced migration reinforce disadvantage and further limit opportunities. Cultural…

State-of-the-Art Opportunities. Hispanic Special Report: Careers in Engineering.

ERIC Educational Resources Information Center

Heller, Michele

1992-01-01

Although the demand for electrical, defense, and computer science engineers has dropped sharply, opportunities exist for Hispanics in computer communication and integration, miniaturization of electronic components, environmental, and genetic and biomedical engineering. Engineers should diversify their skills to adapt to the changing field. (KS)

Vandalized: Educational Opportunity, Inclusion, and Academic Outsiders at the University of Idaho

ERIC Educational Resources Information Center

Clyde, Scott

2013-01-01

This dissertation employed a critical action research methodology to problematize the University of Idaho's observed failure to successfully integrate nontraditional scholars into its academic culture. This dissertation explores the appropriate role and responsibility of the embedded educational opportunity programs in assisting academic outsiders…

Opportunities and Challenges for Interdisciplinary Research and Education

ERIC Educational Resources Information Center

Lin, Henry

2008-01-01

Interdisciplinary research and education (IDRE) holds center stage in current academic discussions. Despite the widespread agreement on the promises of IDRE, barriers for effective IDRE implementation remain significant. This study explored the opportunities and challenges of IDRE in integrated soil and water sciences at the Pennsylvania State…

Expedite the Processing of Unpressurized Payloads to the International Space Station Using the ExPRESS Pallet

NASA Technical Reports Server (NTRS)

Bacskay, Allen S.; Gilbert, Paul A. (Technical Monitor)

2002-01-01

The Expedite the PRocessing of Experiments to Space Station (ExPRESS) Pallet will be used as an experiment platform for external/unpressurized payloads to be flown aboard the International Space Station (ISS). The purpose of the ExPRESS Pallet is to provide an easy access to the ISS for Scientific Investigators that require an external platform for their experiment hardware. As the name of the ExPRESS Pallet implies, the objective of the ExPRESS program is to provide a simplified integration process in a short time period (24 months) for payloads to be flown on the ISS. The ExPRESS Pallet provides unique opportunities for research across many science disciplines, including earth observation, communications, solar and deep space viewing, and long-term exposure. The ExPRESS Pallet provides access to Ram, Wake, Nadir, Zenith and Earth Limb for viewing and exposure to the space environment. The ExPRESS Pallet will provide standard physical payload interfaces, and a standard integration template. The ExPS consists of the Pallet structure, payload Adapters, a subsystem assembly that includes data controller, power distribution and conversion, and Extra Vehicular Robotics compatibility. The ExPRESS Pallet provides the capability to changeout payloads on-orbit via the ExPRESS Pallet Adapter (ExPA). The following paragraphs will describe the Services and Accommodations available to the Payload developers by the ExPRESS Pallet and a brief description of the Integration process. More detailed information on the ExPRESS Pallet can be found in the ExPRESS Pallet Payload Accommodations Handbook, SSP 52000-PAH-EPP.

The integration of FMEA with other problem solving tools: A review of enhancement opportunities

NASA Astrophysics Data System (ADS)

Ng, W. C.; Teh, S. Y.; Low, H. C.; Teoh, P. C.

2017-09-01

Failure Mode Effect Analysis (FMEA) is one the most effective and accepted problem solving (PS) tools for most of the companies in the world. Since FMEA was first introduced in 1949, practitioners have implemented FMEA in various industries for their quality improvement initiatives. However, studies have shown that there are drawbacks that hinder the effectiveness of FMEA for continuous quality improvement from product design to manufacturing. Therefore, FMEA is integrated with other PS tools such as inventive problem solving methodology (TRIZ), Quality Function Deployment (QFD), Root Cause Analysis (RCA) and seven basic tools of quality to address the drawbacks. This study begins by identifying the drawbacks in FMEA. A comprehensive literature review on the integration of FMEA with other tools is carried out to categorise the integrations based on the drawbacks identified. The three categories are inefficiency of failure analysis, psychological inertia and neglect of customers’ perspective. This study concludes by discussing the gaps and opportunities in the integration for future research.

Embedding technology into inter-professional best practices in home safety evaluation.

PubMed

Burns, Suzanne Perea; Pickens, Noralyn Davel

2017-08-01

To explore inter-professional home evaluators' perspectives and needs for building useful and acceptable decision-support tools for the field of home modifications. Twenty semi-structured interviews were conducted with a range of home modification professionals from different regions of the United States. The interview transcripts were analyzed with a qualitative, descriptive, perspective approach. Technology supports current best practice and has potential to inform decision making through features that could enhance home evaluation processes, quality, efficiency and inter-professional communication. Technological advances with app design have created numerous opportunities for the field of home modifications. Integrating technology and inter-professional best practices will improve home safety evaluation and intervention development to meet client-centred and societal needs. Implications for rehabilitation Understanding home evaluators technology needs for home safety evaluations contributes to the development of app-based assessments. Integrating inter-professional perspectives of best practice and technological needs in an app for home assessments improves processes. Novice and expert home evaluators would benefit from decision support systems embedded in app-based assessments. Adoption of app-based assessment would improve efficiency while remaining client-centred.

The ISS EXPRESS Rack: An Innovative Approach of Rapid Integration

NASA Technical Reports Server (NTRS)

Sledd, Annette M.

2000-01-01

The EXpedite the PRocessing of Experiments to Space Station or EXPRESS Rack System, was developed to provide Space Station accommodations for small, subrack payloads. The EXPRESS Rack accepts Space Shuttle middeck locker type payloads and International Subrack Interface Standard (ISIS) Drawer payloads, allowing previously flown payloads an opportunity to transition to the International Space Station. The EXPRESS Rack provides power, data, command and control, video, water cooling, air cooling, vacuum exhaust, and Nitrogen supply to payloads. The EXPRESS Rack system also includes transportation racks to transport payloads to and from the Space Station, Suitcase Simulators to allow a payload developer to verify power and data interfaces at the development site, Functional Checkout Units to allow Payload checkout at KSC prior to launch, and trainer racks for the astronauts to learn how to operate the EXPRESS Racks prior to flight. Standard hardware and software interfaces provided by the EXPRESS Rack simplify the analytical and physical integration processes, and facilitates simpler ISS payload development. The EXPRESS Rack has also formed the basis for the U.S. Life Sciences payload racks and the Window Observational Research Facility on Space Station.

Assessing your competitors' application of CIM/CIP. [Computer Integrated Manufacturing/Processing

DOE Office of Scientific and Technical Information (OSTI.GOV)

King, M.J.; Evans, H.N.

1993-07-01

As part of the authors consulting assignments, they are frequently asked to describe what is best industry practice in the area of computer integrated manufacturing/processing (CIM/CIP). This might be specific to a particular piece, such as advanced controls or a laboratory system. Often it is in response to the enormous publicity given to CIM/CIP--begging the question, Who in the hydrocarbon industry is actually doing it '' Although much of this information is available to consultants, client confidentiality precludes its release. Instead, included is a questionnaire intended to be completed by representatives of manufacturing sites. The data gathered will be analyzedmore » and reported in a future issue. The intent is to give anyone who has completed the questionnaire the opportunity to assess the position of his or her site with respect to the competition. To show how this might work a prototype study was completed. This included an estimate of the advanced control benefits achieved in 68 refineries in Western Europe. So that sites could be compared, these were expressed as a percentage of the maximum economically achievable.« less

Deep Proton Writing for the rapid prototyping of polymer micro-components for optical interconnects and optofluidics

NASA Astrophysics Data System (ADS)

Van Erps, Jürgen; Vervaeke, Michael; Ottevaere, Heidi; Hermanne, Alex; Thienpont, Hugo

2013-07-01

The use of photonics in data communication and numerous other industrial applications brought plenty of prospects for innovation and opened up different unexplored market opportunities. This is a major driving force for the fabrication of micro-optical and micro-mechanical structures and their accurate alignment and integration into opto-mechanical modules and systems. To this end, we present Deep Proton Writing (DPW) as a powerful rapid prototyping technology for such micro-components. The DPW process consists of bombarding polymer samples (PMMA or SU-8) with swift protons, which results after chemical processing steps in high-quality micro-optical components. One of the strengths of the DPW micro-fabrication technology is the ability to fabricate monolithic building blocks that include micro-optical and mechanical functionalities which can be precisely integrated into more complex photonic systems. In this paper we comment on how we shifted from using 8.3 to 16.5 MeV protons for DPW and give some examples of micro-optical and micro-mechanical components recently fabricated through DPW, targeting applications in optical interconnections and in optofluidics.

Integrating risk minimization planning throughout the clinical development and commercialization lifecycle: an opinion on how drug development could be improved

PubMed Central

Morrato, Elaine H; Smith, Meredith Y

2015-01-01

Pharmaceutical risk minimization programs are now an established requirement in the regulatory landscape. However, pharmaceutical companies have been slow to recognize and embrace the significant potential these programs offer in terms of enhancing trust with health care professionals and patients, and for providing a mechanism for bringing products to the market that might not otherwise have been approved. Pitfalls of the current drug development process include risk minimization programs that are not data driven; missed opportunities to incorporate pragmatic methods and market-based insights, outmoded tools and data sources, lack of rapid evaluative learning to support timely adaption, lack of systematic approaches for patient engagement, and questions on staffing and organizational infrastructure. We propose better integration of risk minimization with clinical drug development and commercialization work streams throughout the product lifecycle. We articulate a vision and propose broad adoption of organizational models for incorporating risk minimization expertise into the drug development process. Three organizational models are discussed and compared: outsource/external vendor, embedded risk management specialist model, and Center of Excellence. PMID:25750537

Perspectives on the production of polyhydroxyalkanoates in biorefineries associated with the production of sugar and ethanol.

PubMed

Silva, Luiziana Ferreira; Taciro, Marilda Keico; Raicher, Gil; Piccoli, Rosane Aparecida Moniz; Mendonça, Thatiane Teixeira; Lopes, Mateus Schreiner Garcez; Gomez, José Gregório Cabrera

2014-11-01

Polyhydroxyalkanoates (PHA) are biodegradable and biocompatible bacterial thermoplastic polymers that can be obtained from renewable resources. The high impact of the carbon source in the final cost of this polymer has been one of the major limiting factors for PHA production and agricultural residues, mainly lignocellulosic materials, have gained attention to overcome this problem. In Brazil, production of 2nd generation ethanol from the glucose fraction, derived from sugarcane bagasse hydrolysate has been studied. The huge amounts of remaining xylose will create an opportunity for the development of other bioprocesses, generating new products to be introduced into a biorefinery model. Although PHA production from sucrose integrated to a 1G ethanol and sugar mill has been proposed in the past, the integration of the process of 2G ethanol in the context of a biorefinery will provide enormous amounts of xylose, which could be applied to produce PHA, establishing a second-generation of PHA production process. Those aspects and perspectives are presented in this article. Copyright © 2014 Elsevier B.V. All rights reserved.

Integration of the Opportunity-Ability-Motivation behavior change framework into a coaching-based WHO Safe Childbirth Checklist program in India.

PubMed

Hirschhorn, Lisa R; Krasne, Margaret; Maisonneuve, Jenny; Kara, Nabihah; Kalita, Tapan; Henrich, Natalie; Rana, Darpan; Maji, Pinki; Delaney, Megan M; Firestone, Rebecca; Sharma, Narender; Kumar, Vishwajeet; Gawande, Atul A; Semrau, Katherine E A

2018-06-03

To evaluate whether integration of the Opportunity-Ability-Motivation plus Supplies (OAMS) framework into coaching improved the delivery of essential birth practices in a low-resource setting. This prospective mixed-methods study used routine coaching visit data obtained from the first eight intervention facilities of the BetterBirth trial in Uttar Pradesh, India, between December 19, 2014, and October 21, 2015. The 8-month intervention was peer coaching that integrated the OAMS framework to support uptake of the WHO Safe Childbirth Checklist. Descriptive statistics were used to measure nonadherence to essential birth practices. The frequency and accuracy of coaches' coding of barriers and the appropriateness of chosen resolution strategies to measure feasibility, acceptability, and fidelity of using OAMS, were assessed. Coaches observed 666 deliveries, including 12 602 practices. Overall, essential practice nonadherence decreased from 15.6% (262/1675 practices observed) to 4.5% (4/88 practices) (P<0.001). Of the 1048 barriers identified, opportunity (556 [53.1%]) and motivation (287 [27.4%]) were the most frequently reported categories; the frequency of both decreased over time (P=0.003 and P<0.001, respectively). The coaches appropriately categorized 930 (99.8%) of 932 barriers and provided an appropriate strategy for 800 (85.8%). The commonest reason for unaddressed barriers was lack of coaching opportunities. Successful integration of OAMS framework into delivery attendant coaching enabled coaches to rapidly diagnose barriers to practice adherence and develop responsive strategies. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

Developing a mental health care plan in a low resource setting: the theory of change approach.

PubMed

Hailemariam, Maji; Fekadu, Abebaw; Selamu, Medhin; Alem, Atalay; Medhin, Girmay; Giorgis, Tedla Wolde; DeSilva, Mary; Breuer, Erica

2015-09-28

Scaling up mental healthcare through integration into primary care remains the main strategy to address the extensive unmet mental health need in low-income countries. For integrated care to achieve its goal, a clear understanding of the organisational processes that can promote and hinder the integration and delivery of mental health care is essential. Theory of Change (ToC), a method employed in the planning, implementation and evaluation of complex community initiatives, is an innovative approach that has the potential to assist in the development of a comprehensive mental health care plan (MHCP), which can inform the delivery of integrated care. We used the ToC approach to develop a MHCP in a rural district in Ethiopia. The work was part of a cross-country study, the Programme for Improving Mental Health Care (PRIME) which focuses on developing evidence on the integration of mental health in to primary care. An iterative ToC development process was undertaken involving multiple workshops with stakeholders from diverse backgrounds that included representatives from the community, faith and traditional healers, community associations, non-governmental organisations, Zonal, Regional and Federal level government offices, higher education institutions, social work and mental health specialists (psychiatrists and psychiatric nurses). The objective of this study is to report the process of implementing the ToC approach in developing mental health care plan. A total of 46 persons participated in four ToC workshops. Four critical path dimensions were identified: community, health facility, administrative and higher level care organisation. The ToC participants were actively engaged in the process and the ToC encouraged strong commitment among participants. Key opportunities and barriers to implementation and how to overcome these were suggested. During the workshops, a map incorporating the key agreed outcomes and outcome indicators was developed and finalized later. The ToC approach was found to be an important component in the development of the MHCP and to encourage broad political support for the integration of mental health services into primary care. The method may have broader applicability in planning complex health interventions in low resource settings.

[Standard of integration management at company level and its auditing].

PubMed

Flach, T; Hetzel, C; Mozdzanowski, M; Schian, H-M

2006-10-01

Responsibility at company level for the employment of workers with health-related problems or disabilities has increased, inter alia because of integration management at company level according to section 84 (2) of the German Social Code Book IX. Although several recommendations exist, no standard is available for auditing and certification. Such a standard could be a basis for granting premiums according to section 84 (3) of Book IX of the German Social Code. AUDIT AND CERTIFICATION: One product of the international "disability management" movement is the "Consensus Based Disability Management Audit" (CBDMA). The Audit is a systematic and independent measurement of the effectiveness of integration management at company level. CBDMA goals are to give evidence of the quality of the integration management implemented, to identify opportunities for improvement and recommend appropriate corrective and preventive action. In May 2006, the integration management of Ford-Werke GmbH Germany with about 23 900 employees was audited and certified as the first company in Europe. STANDARD OF INTEGRATION MANAGEMENT AT COMPANY LEVEL: In dialogue with corporate practitioners, the international standard of CBDMA has been adapted, completed and verified concerning its practicability. Process orientation is the key approach, and the structure is similar to DIN EN ISO 9001:2000. Its structure is as follows: (1) management-labour responsibility (goals and objectives, program planning, management-labour review), (2) management of resources (disability manager and DM team, employees' participation, cooperation with external partners, infrastructure), (3) communication (internal and external public relations), (4) case management (identifying cases, contact, situation analysis, planning actions, implementing actions and monitoring, process and outcome evaluation), (5) analysis and improvement (analysis and program evaluation), (6) documentation (manual, records).

From Foucault to Freire through Facebook: Toward an Integrated Theory of mHealth

ERIC Educational Resources Information Center

Bull, Sheana; Ezeanochie, Nnamdi

2016-01-01

Objective: To document the integration of social science theory in literature on mHealth (mobile health) and consider opportunities for integration of classic theory, health communication theory, and social networking to generate a relevant theory for mHealth program design. Method: A secondary review of research syntheses and meta-analyses…

Strengthening Integrated Learning: Towards a New Era for Pluriliteracies and Intercultural Learning

ERIC Educational Resources Information Center

Coyle, Do

2015-01-01

The expansion of Content and Language Integrated Learning (CLIL) on a global scale has brought to the fore challenges of how alternative, more holistic approaches to learning might transform classrooms into language-rich transcultural environments. Integrated approaches can offer learners opportunities to engage in meaning-making and language…

UAS Integration in the NAS Project Overview: RTCA SC-228 Plenary DAA Working Group 5

NASA Technical Reports Server (NTRS)

Randall, Debra K.

2014-01-01

The presentation is intended to allow the public to know and understand NASA's plans for integrated test to allow them the opportunity to provide feedback and suggestions. The integrated testing will support verification and validation of the RTCA SC-228 UAS minimum operation performance standard requirements.

Integrating Curriculum: A Case Study of Teaching Global Education

ERIC Educational Resources Information Center

Ferguson-Patrick, Kate; Reynolds, Ruth; Macqueen, Suzanne

2018-01-01

Despite widespread support for integrated approaches to teaching, classroom practice reveals a lack of implementation. This paper explores challenges and opportunities in teaching an integrated curriculum, and connects this with the contemporary notion of a twenty-first century curriculum and pedagogy. A case study of Global Education (GE) is used…

Integral Students' Experiences: Measuring Instructional Quality and Instructors' Challenges in Calculus 1 Lessons

ERIC Educational Resources Information Center

Hong, Dae S.; Choi, Kyong Mi; Hwang, Jihyun; Runnalls, Cristina

2017-01-01

In this study, we examined 10 integral lessons to understand students' opportunities to learn cognitively challenging tasks and maintain cognitive demand during integral lessons. Our findings reveal issues with implemented tasks as well as the way these tasks were presented to students. We also examined mathematicians' reasons behind their…

23 CFR Appendix D to Subpart D of... - Equal Opportunity Compliance Review Process Flow Chart

Code of Federal Regulations, 2010 CFR

2010-04-01

... 23 Highways 1 2010-04-01 2010-04-01 false Equal Opportunity Compliance Review Process Flow Chart D Appendix D to Subpart D of Part 230 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION..., Subpt. D, App. D Appendix D to Subpart D of Part 230—Equal Opportunity Compliance Review Process Flow...

Modeling tools for an Integrated River-Delta-Sea system investigation: the Pan-European Research Infrastructure DANUBIUS-RI philosophy

NASA Astrophysics Data System (ADS)

Umgiesser, Georg; Bellafiore, Debora; De Pascalis, Francesca; Icke, Joost; Stanica, Adrian

2017-04-01

The DANUBIUS Research Infrastructure (DANUBIUS-RI) is a new initiative to address the challenges and opportunities of research on large river- sea (RS) systems. DANUBIUS-RI is a distributed pan-European RI that will provide a platform for interdisciplinary research. It will deal with RS investigation through facilities and expertise from a large number of European institutions becoming a 'one-stop shop' for knowledge exchange in managing RS systems, ranging from freshwater to marine research. Globally, RS systems are complex and dynamic, with huge environmental, social and economic value. They are poorly understood but under increasing pressure through pollution, hydraulic engineering, water supply, energy, flood control and erosion. RS systems in Europe are among the most impacted globally, after centuries of industrialisation, urbanisation and agricultural intensification. Improved understanding is essential to avoid irreversible degradation and for restoration. DANUBIUS-RI will provide, among a number of other facilities concerning observations, analyses, impacts' evaluation, a modeling node that will provide integrated up-to-date tools, at locations of high scientific importance and opportunity, covering the RS systems - from source (upper parts of rivers - mountain lakes) to the transition with coastal seas. Modeling will be one of the major services provided by DANUBIUS-RI, relying on the inputs from the whole RI. RS systems are challenging from a modelling point of view, because of the complex morphology and the wide temporal and spatial range of processes occurring. Scale interaction plays a central role, considering the different hydro-eco-morphological processes on the large (basin) and small (local, coast, rivers, lagoons) scale. Currently, different model applications are made for the different geographical domains, and also for subsets of the processes. For instance there are separate models for rainfall runoff in the catchment, a sewer model for the urban area and a water quality model for the sea. Obviously, the subsystems interact with each other: water flows from the catchments to the rivers and into the sea. The rainfall runoff from the upstream catchment picks up the emissions and the river transports the substances via the estuaries to the sea. In the sea, the substances interact with the marine ecosystem. The challenge for the modeling of river - sea systems is (1) the integration of models for the geographical domains, (2) the integration of physical, chemical, ecological and socio-economical processes and (3) the exploration and application of new data sources. The modeling strategy that is starting to be shaped within DANUBIUS-RI will provide relocatable tools and suitable techniques to be efficiently applied in the different geographical areas, integrating the DANUBIUS-RI modeling skills and showing high performance modeling solutions for the investigation of RS systems. Moreover, a technological advanced platform for modeling services, in terms of software and shared data will be created. A preliminary sketch of the organization of the DANUBIUS modeling node and examples of field of action for RS systems investigation will be provided.

A Coprolite Mystery: Who Dung It?

ERIC Educational Resources Information Center

Clary, Renee; Wandersee, James

2011-01-01

Discover the secrets contained in fossilized feces. Few topics in middle school classrooms capture students' enthusiasm and interest as do coprolites. These trace fossils offer classroom opportunities for integrated life and Earth sciences study, a stranger-than-fiction history of science, and an opportunity to solve mysteries. (Contains 8…

The Olympics: An Educational Opportunity. Enrichment Units, 7-9.

ERIC Educational Resources Information Center

United States Olympic Committee, Colorado Springs, CO.

The learning activities presented in this handbook illustrate educational opportunities related to participation in competitive activity as exemplified by the Olympic Games. Designed for use with students in grades seven through nine, these learning units may be integrated with the existing curriculum for the class. Subjects offered include…

The Elephant in the Classroom

ERIC Educational Resources Information Center

Stillman, Jennifer Burns

2013-01-01

The gentrification of many the country's big cities is providing a once-in-a-generation opportunity to create a large number of racially and socioeconomically integrated schools. But to capitalize on this opportunity, urban schools that currently serve a predominantly poor and minority population must find a way to attract and retain the…

Evaluation and Opportunities in Overtraining Approaches

ERIC Educational Resources Information Center

Roose, Jolanda; de Vries, Wouter R.; Schmikli, Sandor L.; Backx, Frank J. G.; van Doornen, Lorenz J. P.

2009-01-01

Overtraining (OT) as a sports phenomenon can be caused by stressors on various levels (physical, emotional, psychological, and social) and evokes responses on these levels. This study evaluated research and new opportunities in the field of OT by introducing an integrated multidisciplinary approach, based on the single and multistressors approach.…

Civic Rhythms in an Informal, Media-Rich Learning Program

ERIC Educational Resources Information Center

Hollett, Ty; Ehret, Christian

2017-01-01

Increasingly, adult mentors in informal, media-rich settings, like libraries and museums, seek to integrate both learning and civic engagement opportunities for youth into designed programming. This article illustrates how youth open and sustain opportunities for civic engagement over the course of a six-month, youth-driven program--Metro:…

"Question Moments": A Rolling Programme of Question Opportunities in Classroom Science

ERIC Educational Resources Information Center

Pedrosa-de-Jesus, Helena; Leite, Sara; Watts, Mike

2016-01-01

This naturalistic study integrates specific "question moments" into lesson plans to increase pupils' classroom interactions. A range of tools explored students' ideas by providing students with opportunities to ask and write questions. Their oral and written outcomes provide data on individual and group misunderstandings. Changes to the…

Opportunities for Improving the Energy Efficiency of Multi-Modal Intra-City Freight Movement

DOE Office of Scientific and Technical Information (OSTI.GOV)

Walkowicz, Kevin; Duran, Adam

This poster focuses on the National Renewable Energy Laboratory's analysis of opportunities for freight movement energy savings via optimization and integration of existing/emerging intra-city goods delivery modes as well as an assessment of the efficacy and energy consumption impact of new technologies.

Applications of Generative Learning for the Survey of International Economics Course

ERIC Educational Resources Information Center

Sharp, David C.; Knowlton, Dave S.; Weiss, Renee E.

2005-01-01

Generative learning provides students with opportunities to organize course content, integrate new content with students' current knowledge, and elaborate on course content by making connections to real-world events. These opportunities promote less reliance on professors' lectures and simultaneously create more self-reliance among students. The…

Incorporating the Internet into the Marketing Classroom: Problems, Opportunities and Thoughts.

ERIC Educational Resources Information Center

Phillips, Melodie R.; Horton, Veronica

1998-01-01

Summarizes some of the opportunities and difficulties in integrating Internet-based activities in the traditional marketing classroom, and offers ideas for future applications and research. Marketing specialists are encouraged to examine both how, and when, the Internet can be used productively in the classroom. (Author/MSE)

Integrating Early Writing into Science Instruction in Preschool

ERIC Educational Resources Information Center

Wheatley, Barbara C.; Gerde, Hope K.; Cabell, Sonia Q.

2016-01-01

Providing children with early writing opportunities in preschool is a meaningful way to facilitate their language and literacy learning. Young children have an innate curiosity of the natural world around them that motivates their learning; therefore science experiences are logical areas in which to incorporate early writing opportunities.…

Integrated biomass technologies: future vision for optimally using wood and biomass

Treesearch

Jerrold E. Winandy; Alan W. Rudie; R. Sam Williams; Theodore H. Wegner

2008-01-01

Exciting new opportunities are emerging for sustainably meeting many global energy needs and simultaneously creating high value biobased consumer and construction products from wood, forest and agricultural residues, and other biobased materials. In addition to traditional value added biobased products, such as lumber, paper, paperboard, and composites, opportunities...

Teaching Social Media Journalism: Challenges and Opportunities for Future Curriculum Design

ERIC Educational Resources Information Center

Bor, Stephanie E.

2014-01-01

In response to the growing demand for digitally competent employees in the news media industry, journalism schools are cautiously integrating social media reporting into their curriculum. This study explores techniques for teaching news reporting on social media platforms focusing on challenges and opportunities for learning engagement that…

Promoting equity through integrated early child development and nutrition interventions.

PubMed

Black, Maureen M; Dewey, Kathryn G

2014-01-01

Sustainable development, a foundation of the post-2015 global agenda, depends on healthy and productive citizens. The origins of adult health begin early in life, stemming from genetic-environmental interactions that include adequate nutrition and opportunities for responsive learning. Inequities associated with inadequate nutrition and early learning opportunities can undermine children's health and development, thereby compromising their productivity and societal contributions. Transactional theory serves as a useful framework for examining the associations that link early child development and nutrition because it emphasizes the interplay that occurs between children and the environment, mediated through caregiver interactions. Although single interventions targeting early child development or nutrition can be effective, there is limited evidence on the development, implementation, evaluation, and scaling up of integrated interventions. This manuscript introduces a special edition of papers on six topics central to integrated child development/nutrition interventions: (1) review of integrated interventions; (2) methods and topics in designing integrated interventions; (3) economic considerations related to integrated interventions; (4) capacity-building considerations; (5) examples of integrated interventions; and (6) policy implications of integrated interventions. Ensuring the health and development of infants and young children through integrated child development/nutrition interventions promotes equity, a critical component of sustainable development. © 2014 New York Academy of Sciences.

A framework for different levels of integration of computational models into web-based virtual patients.

PubMed

Kononowicz, Andrzej A; Narracott, Andrew J; Manini, Simone; Bayley, Martin J; Lawford, Patricia V; McCormack, Keith; Zary, Nabil

2014-01-23

Virtual patients are increasingly common tools used in health care education to foster learning of clinical reasoning skills. One potential way to expand their functionality is to augment virtual patients' interactivity by enriching them with computational models of physiological and pathological processes. The primary goal of this paper was to propose a conceptual framework for the integration of computational models within virtual patients, with particular focus on (1) characteristics to be addressed while preparing the integration, (2) the extent of the integration, (3) strategies to achieve integration, and (4) methods for evaluating the feasibility of integration. An additional goal was to pilot the first investigation of changing framework variables on altering perceptions of integration. The framework was constructed using an iterative process informed by Soft System Methodology. The Virtual Physiological Human (VPH) initiative has been used as a source of new computational models. The technical challenges associated with development of virtual patients enhanced by computational models are discussed from the perspectives of a number of different stakeholders. Concrete design and evaluation steps are discussed in the context of an exemplar virtual patient employing the results of the VPH ARCH project, as well as improvements for future iterations. The proposed framework consists of four main elements. The first element is a list of feasibility features characterizing the integration process from three perspectives: the computational modelling researcher, the health care educationalist, and the virtual patient system developer. The second element included three integration levels: basic, where a single set of simulation outcomes is generated for specific nodes in the activity graph; intermediate, involving pre-generation of simulation datasets over a range of input parameters; advanced, including dynamic solution of the model. The third element is the description of four integration strategies, and the last element consisted of evaluation profiles specifying the relevant feasibility features and acceptance thresholds for specific purposes. The group of experts who evaluated the virtual patient exemplar found higher integration more interesting, but at the same time they were more concerned with the validity of the result. The observed differences were not statistically significant. This paper outlines a framework for the integration of computational models into virtual patients. The opportunities and challenges of model exploitation are discussed from a number of user perspectives, considering different levels of model integration. The long-term aim for future research is to isolate the most crucial factors in the framework and to determine their influence on the integration outcome.

A Framework for Different Levels of Integration of Computational Models Into Web-Based Virtual Patients

PubMed Central

Narracott, Andrew J; Manini, Simone; Bayley, Martin J; Lawford, Patricia V; McCormack, Keith; Zary, Nabil

2014-01-01

Background Virtual patients are increasingly common tools used in health care education to foster learning of clinical reasoning skills. One potential way to expand their functionality is to augment virtual patients’ interactivity by enriching them with computational models of physiological and pathological processes. Objective The primary goal of this paper was to propose a conceptual framework for the integration of computational models within virtual patients, with particular focus on (1) characteristics to be addressed while preparing the integration, (2) the extent of the integration, (3) strategies to achieve integration, and (4) methods for evaluating the feasibility of integration. An additional goal was to pilot the first investigation of changing framework variables on altering perceptions of integration. Methods The framework was constructed using an iterative process informed by Soft System Methodology. The Virtual Physiological Human (VPH) initiative has been used as a source of new computational models. The technical challenges associated with development of virtual patients enhanced by computational models are discussed from the perspectives of a number of different stakeholders. Concrete design and evaluation steps are discussed in the context of an exemplar virtual patient employing the results of the VPH ARCH project, as well as improvements for future iterations. Results The proposed framework consists of four main elements. The first element is a list of feasibility features characterizing the integration process from three perspectives: the computational modelling researcher, the health care educationalist, and the virtual patient system developer. The second element included three integration levels: basic, where a single set of simulation outcomes is generated for specific nodes in the activity graph; intermediate, involving pre-generation of simulation datasets over a range of input parameters; advanced, including dynamic solution of the model. The third element is the description of four integration strategies, and the last element consisted of evaluation profiles specifying the relevant feasibility features and acceptance thresholds for specific purposes. The group of experts who evaluated the virtual patient exemplar found higher integration more interesting, but at the same time they were more concerned with the validity of the result. The observed differences were not statistically significant. Conclusions This paper outlines a framework for the integration of computational models into virtual patients. The opportunities and challenges of model exploitation are discussed from a number of user perspectives, considering different levels of model integration. The long-term aim for future research is to isolate the most crucial factors in the framework and to determine their influence on the integration outcome. PMID:24463466

Genetically identified spinal interneurons integrating tactile afferents for motor control

PubMed Central

Panek, Izabela; Farah, Carl

2015-01-01

Our movements are shaped by our perception of the world as communicated by our senses. Perception of sensory information has been largely attributed to cortical activity. However, a prior level of sensory processing occurs in the spinal cord. Indeed, sensory inputs directly project to many spinal circuits, some of which communicate with motor circuits within the spinal cord. Therefore, the processing of sensory information for the purpose of ensuring proper movements is distributed between spinal and supraspinal circuits. The mechanisms underlying the integration of sensory information for motor control at the level of the spinal cord have yet to be fully described. Recent research has led to the characterization of spinal neuron populations that share common molecular identities. Identification of molecular markers that define specific populations of spinal neurons is a prerequisite to the application of genetic techniques devised to both delineate the function of these spinal neurons and their connectivity. This strategy has been used in the study of spinal neurons that receive tactile inputs from sensory neurons innervating the skin. As a result, the circuits that include these spinal neurons have been revealed to play important roles in specific aspects of motor function. We describe these genetically identified spinal neurons that integrate tactile information and the contribution of these studies to our understanding of how tactile information shapes motor output. Furthermore, we describe future opportunities that these circuits present for shedding light on the neural mechanisms of tactile processing. PMID:26445867

Network-based integration of systems genetics data reveals pathways associated with lignocellulosic biomass accumulation and processing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mizrachi, Eshchar; Verbeke, Lieven; Christie, Nanette

As a consequence of their remarkable adaptability, fast growth, and superior wood properties, eucalypt tree plantations have emerged as key renewable feedstocks (over 20 million ha globally) for the production of pulp, paper, bioenergy, and other lignocellulosic products. However, most biomass properties such as growth, wood density, and wood chemistry are complex traits that are hard to improve in long-lived perennials. Systems genetics, a process of harnessing multiple levels of component trait information (e.g., transcript, protein, and metabolite variation) in populations that vary in complex traits, has proven effective for dissecting the genetics and biology of such traits. We havemore » applied a network-based data integration (NBDI) method for a systems-level analysis of genes, processes and pathways underlying biomass and bioenergy-related traits using a segregating Eucalyptus hybrid population. We show that the integrative approach can link biologically meaningful sets of genes to complex traits and at the same time reveal the molecular basis of trait variation. Gene sets identified for related woody biomass traits were found to share regulatory loci, cluster in network neighborhoods, and exhibit enrichment for molecular functions such as xylan metabolism and cell wall development. These findings offer a framework for identifying the molecular underpinnings of complex biomass and bioprocessing-related traits. Furthermore, a more thorough understanding of the molecular basis of plant biomass traits should provide additional opportunities for the establishment of a sustainable bio-based economy.« less

Network-based integration of systems genetics data reveals pathways associated with lignocellulosic biomass accumulation and processing

DOE PAGES

Mizrachi, Eshchar; Verbeke, Lieven; Christie, Nanette; ...

2017-01-17

As a consequence of their remarkable adaptability, fast growth, and superior wood properties, eucalypt tree plantations have emerged as key renewable feedstocks (over 20 million ha globally) for the production of pulp, paper, bioenergy, and other lignocellulosic products. However, most biomass properties such as growth, wood density, and wood chemistry are complex traits that are hard to improve in long-lived perennials. Systems genetics, a process of harnessing multiple levels of component trait information (e.g., transcript, protein, and metabolite variation) in populations that vary in complex traits, has proven effective for dissecting the genetics and biology of such traits. We havemore » applied a network-based data integration (NBDI) method for a systems-level analysis of genes, processes and pathways underlying biomass and bioenergy-related traits using a segregating Eucalyptus hybrid population. We show that the integrative approach can link biologically meaningful sets of genes to complex traits and at the same time reveal the molecular basis of trait variation. Gene sets identified for related woody biomass traits were found to share regulatory loci, cluster in network neighborhoods, and exhibit enrichment for molecular functions such as xylan metabolism and cell wall development. These findings offer a framework for identifying the molecular underpinnings of complex biomass and bioprocessing-related traits. Furthermore, a more thorough understanding of the molecular basis of plant biomass traits should provide additional opportunities for the establishment of a sustainable bio-based economy.« less

Identification of anthropogenic impact on nitrogen cycling using stable isotopes and distibuted hydrologic modeling

NASA Astrophysics Data System (ADS)

Macko, S. A.; O'Connell, M. T.; Fu, Y.

2016-12-01

The Najinhe watershed is a topographically diverse, heavily agricultural watershed in northeastern China that provides opportunities for identification of the impact of land use on nitrogen cycling. Land use, both historic and current, influences the biological processing of nitrogen in a particular area. Soil conditions, including moisture, texture, and organic content, control the capacity of a parcel for processing reactive nitrogen. Compounds derived from natural and anthropogenic sources exhibit characteristic ratios of stable isotopes of nitrogen and oxygen that serve as tracers of origin as well as integrators of biological processes. A distributed hydrologic model coupled with one focusing on reactive transport is able to help determine locations with the highest impact on the dissolved N in this system. Gaussian Markov Random Fields were used to determine the biogeochemical influence of model locations whereas δ15N measurements from NO3- and NH4+ in soil extracts were used to calibrate and validate model predictions based on measured precipitation and streamflow values. Sources were integrated using a Bayesian mixing model to determine likely fate and transport parameters for various N inputs to the watershed. The application of the coupled hydrologic and transport models to a village scale catchment suggests integration and expansion to larger watersheds on the basin scale. Identification of sensitive parcels on multiple spatial scales can direct targeted land management efforts to mitigate ecological and health effects of reactive N in surface waters.

Network-based integration of systems genetics data reveals pathways associated with lignocellulosic biomass accumulation and processing.

PubMed

Mizrachi, Eshchar; Verbeke, Lieven; Christie, Nanette; Fierro, Ana C; Mansfield, Shawn D; Davis, Mark F; Gjersing, Erica; Tuskan, Gerald A; Van Montagu, Marc; Van de Peer, Yves; Marchal, Kathleen; Myburg, Alexander A

2017-01-31

As a consequence of their remarkable adaptability, fast growth, and superior wood properties, eucalypt tree plantations have emerged as key renewable feedstocks (over 20 million ha globally) for the production of pulp, paper, bioenergy, and other lignocellulosic products. However, most biomass properties such as growth, wood density, and wood chemistry are complex traits that are hard to improve in long-lived perennials. Systems genetics, a process of harnessing multiple levels of component trait information (e.g., transcript, protein, and metabolite variation) in populations that vary in complex traits, has proven effective for dissecting the genetics and biology of such traits. We have applied a network-based data integration (NBDI) method for a systems-level analysis of genes, processes and pathways underlying biomass and bioenergy-related traits using a segregating Eucalyptus hybrid population. We show that the integrative approach can link biologically meaningful sets of genes to complex traits and at the same time reveal the molecular basis of trait variation. Gene sets identified for related woody biomass traits were found to share regulatory loci, cluster in network neighborhoods, and exhibit enrichment for molecular functions such as xylan metabolism and cell wall development. These findings offer a framework for identifying the molecular underpinnings of complex biomass and bioprocessing-related traits. A more thorough understanding of the molecular basis of plant biomass traits should provide additional opportunities for the establishment of a sustainable bio-based economy.

Opportunities and Challenges in Realizing Universal Access to Obstetric Ultrasound in Sub-Saharan Africa

PubMed Central

Wanyonyi, Sikolia Z; Mariara, Charles Muriuki; Vinayak, Sudhir; Stones, William

2017-01-01

The potential benefits of obstetric ultrasound have yet to be fully realized in sub-Saharan Africa (SSA), despite the region bearing the greatest burden of poor perinatal outcomes. We reviewed the literature for challenges and opportunities of universal access to obstetric ultrasound and explored what is needed to make such access an integral component of maternity care in order to address the massive burden of perinatal morbidity and mortality in SSA. Original peer-reviewed literature was searched in various electronic databases using a ‘realist’ approach. While the available data were inconclusive, they identify many opportunities for potential future research on the subject within the region that can help build a strong case to justify the provision of universal access to ultrasound as an integral component of comprehensive antenatal care. PMID:28596999

Blueprint for a coupled model of sedimentology, hydrology, and hydrogeology in streambeds

NASA Astrophysics Data System (ADS)

Partington, Daniel; Therrien, Rene; Simmons, Craig T.; Brunner, Philip

2017-06-01

The streambed constitutes the physical interface between the surface and the subsurface of a stream. Across all spatial scales, the physical properties of the streambed control surface water-groundwater interactions. Continuous alteration of streambed properties such as topography or hydraulic conductivity occurs through erosion and sedimentation processes. Recent studies from the fields of ecology, hydrogeology, and sedimentology provide field evidence that sedimentological processes themselves can be heavily influenced by surface water-groundwater interactions, giving rise to complex feedback mechanisms between sedimentology, hydrology, and hydrogeology. More explicitly, surface water-groundwater exchanges play a significant role in the deposition of fine sediments, which in turn modify the hydraulic properties of the streambed. We explore these feedback mechanisms and critically review the extent of current interaction between the different disciplines. We identify opportunities to improve current modeling practices. For example, hydrogeological models treat the streambed as a static rather than a dynamic entity, while sedimentological models do not account for critical catchment processes such as surface water-groundwater exchange. We propose a blueprint for a new modeling framework that bridges the conceptual gaps between sedimentology, hydrogeology, and hydrology. Specifically, this blueprint (1) fully integrates surface-subsurface flows with erosion, transport, and deposition of sediments and (2) accounts for the dynamic changes in surface elevation and hydraulic conductivity of the streambed. Finally, we discuss the opportunities for new research within the coupled framework.

Integrating model abstraction into monitoring strategies

USDA-ARS?s Scientific Manuscript database

This study was designed and performed to investigate the opportunities and benefits of integrating model abstraction techniques into monitoring strategies. The study focused on future applications of modeling to contingency planning and management of potential and actual contaminant release sites wi...

Physical, Ecological, and Societal Indicators for the National Climate Assessment

NASA Technical Reports Server (NTRS)

Kenney, Melissa A.; Chen, Robert; Baptista, Sandra R.; Quattrochi, Dale; O'Brien, Sheila

2011-01-01

The National Climate Assessment (NCA) is being conducted under the auspices of the U.S. Global Change Research Program (USGCRP), pursuant to the Global Change Research Act of 1990, Section 106, which requires a report to Congress every 4 years. The current NCA (http://globalchange.gov/what-we-do/assessment/) differs in multiple ways from previous U.S. climate assessment efforts, being: (1) more focused on supporting the Nation s activities in adaptation and mitigation and on evaluating the current state of scientific knowledge relative to climate impacts and trends; (2) a long-term, consistent process for evaluation of climate risks and opportunities and providing information to support decision-making processes within regions and sectors; and (3) establishing a permanent assessment capacity both inside and outside of the federal government. As a part of ongoing, long-term assessment activities, the NCA intends to develop an integrated strategic framework and deploy climate-relevant physical, ecological, and societal indicators. The NCA indicators framework is underdevelopment by the NCA Development and Advisory Committee Indicators Working Group and are envisioned as a relatively small number of policy-relevant integrated indicators designed to provide a consistent, objective, and transparent overview of major variations in climate impacts, vulnerabilities, adaptation, and mitigation activities across sectors, regions, and timeframes. The potential questions that could be addressed by these indicators include: How do we know that there is a changing climate and how is it expected to change in the future? Are important climate impacts and opportunities occurring or predicted to occur in the future? Are we adapting successfully? What are the vulnerabilities and resiliencies given a changing climate? Are we preparing adequately for extreme events? It is not expected that the NCA societal indicators would be linked directly to a single decision or portfolio of decisions, but subsets of indicators, or the data supporting the indicator, might be used to inform decision-making processes such as the development and implementation of climate adaptation strategies in a particular sector or region.

Physical, Ecological, and Societal Indicators for the National Climate Assessment

NASA Astrophysics Data System (ADS)

O'Brien, S.; Kenney, M.; Chen, R. S.; Baptista, S. R.; Quattrochi, D. A.

2011-12-01

The National Climate Assessment (NCA) is being conducted under the auspices of the U.S. Global Change Research Program (USGCRP), pursuant to the Global Change Research Act of 1990, Section 106, which requires a report to Congress every 4 years. The current NCA (http://globalchange.gov/what-we-do/assessment/) differs in multiple ways from previous U.S. climate assessment efforts, being: (1) more focused on supporting the Nation's activities in adaptation and mitigation and on evaluating the current state of scientific knowledge relative to climate impacts and trends; (2) a long-term, consistent process for evaluation of climate risks and opportunities and providing information to support decision-making processes within regions and sectors; and (3) establishing a permanent assessment capacity both inside and outside of the federal government. As a part of ongoing, long-term assessment activities, the NCA intends to develop an integrated strategic framework and deploy climate-relevant physical, ecological, and societal indicators. The NCA indicators framework is underdevelopment by the NCA Development and Advisory Committee Indicators Working Group and are envisioned as a relatively small number of policy-relevant integrated indicators designed to provide a consistent, objective, and transparent overview of major variations in climate impacts, vulnerabilities, adaptation, and mitigation activities across sectors, regions, and timeframes. The potential questions that could be addressed by these indicators include: -How do we know that there is a changing climate and how is it expected to change in the future? -Are important climate impacts and opportunities occurring or predicted to occur in the future? -Are we adapting successfully? -What are the vulnerabilities and resiliencies given a changing climate? -Are we preparing adequately for extreme events? It is not expected that the NCA indicators would be linked directly to a single decision or portfolio of decisions, but subsets of indicators, or the data supporting the indicator, might be used to inform decision-making processes such as the development and implementation of climate adaptation strategies in a particular sector or region.

A GIS-based tool for an integrated assessment of spatial planning trade-offs with aquaculture.

PubMed

Gimpel, Antje; Stelzenmüller, Vanessa; Töpsch, Sandra; Galparsoro, Ibon; Gubbins, Matthew; Miller, David; Murillas, Arantza; Murray, Alexander G; Pınarbaşı, Kemal; Roca, Guillem; Watret, Robert

2018-06-15

The increasing demand for protein from aquaculture will trigger a global expansion of the sector in coastal and offshore waters. While contributing to food security, potential conflicts with other traditional activities such as fisheries or tourism are inevitable, thus calling for decision-support tools to assess aquaculture planning scenarios in a multi-use context. Here we introduce the AquaSpace tool, one of the first Geographic Information System (GIS)-based planning tools empowering an integrated assessment and mapping of 30 indicators reflecting economic, environmental, inter-sectorial and socio-cultural risks and opportunities for proposed aquaculture systems in a marine environment. A bottom-up process consulting more than 350 stakeholders from 10 countries across southern and northern Europe enabled the direct consideration of stakeholder needs when developing the GIS AddIn. The AquaSpace tool is an open source product and builds in the prospective use of open source datasets at a European scale, hence aiming to improve reproducibility and collaboration in aquaculture science and research. Tool outputs comprise detailed reports and graphics allowing key stakeholders such as planners or licensing authorities to evaluate and communicate alternative planning scenarios and to take more informed decisions. With the help of the German North Sea case study we demonstrate here the tool application at multiple spatial scales with different aquaculture systems and under a range of space-related development constraints. The computation of these aquaculture planning scenarios and the assessment of their trade-offs showed that it is entirely possible to identify aquaculture sites, that correspondent to multifarious potential challenges, for instance by a low conflict potential, a low risk of disease spread, a comparable high economic profit and a low impact on touristic attractions. We believe that a transparent visualisation of risks and opportunities of aquaculture planning scenarios helps an effective Marine Spatial Planning (MSP) process, supports the licensing process and simplifies investments. Copyright © 2018 The Authors. Published by Elsevier B.V. All rights reserved.

Organizational Structure as a Determinant of Job Burnout.

PubMed

Bilal, Atif; Ahmed, Hafiz Mushtaq

2017-03-01

This exploratory study determined the impact of organizational structure, particularly participation in decision making, instrumental communication, formalization, integration, and promotional opportunity, on burnout among Pakistani pediatric nurses. Data were collected from pediatric nurses working for Punjab's largest state-run hospital. The findings revealed that participation in decision making, instrumental communication, and promotional opportunity prevented burnout. Formalization contributed to burnout but integration was not related to burnout. Quite interestingly, except for supervisory status, most control variables for this study were not significantly related to emotional burnout. Hence, the hypothesis that organizational structure is a determinant of job burnout was accepted.

Computation in Physics: Resources and Support

NASA Astrophysics Data System (ADS)

Engelhardt, Larry; Caballero, Marcos; Chonacky, Norman; Hilborn, Robert; Lopez Del Puerto, Marie; Roos, Kelly

We will describe exciting new resources and support opportunities that have been developed by ``PICUP'' to help faculty to integrate computation into their physics courses. (``PICUP'' is the ``Partnership for Integration of Computation into Undergraduate Physics''). These resources include editable curricular materials that can be downloaded from the PICUP Collection of the ComPADRE Digital Library: www.compadre.org/PICUP. Support opportunities include week-long workshops during the summer and single-day workshops at national AAPT and APS meetings. This project is funded by the National Science Foundation under DUE IUSE Grants 1524128, 1524493, 1524963, 1525062, and 1525525.

An Integrative Approach to Computational Modelling of the Gene Regulatory Network Controlling Clostridium botulinum Type A1 Toxin Production.

PubMed

Ihekwaba, Adaoha E C; Mura, Ivan; Walshaw, John; Peck, Michael W; Barker, Gary C

2016-11-01

Clostridium botulinum produces botulinum neurotoxins (BoNTs), highly potent substances responsible for botulism. Currently, mathematical models of C. botulinum growth and toxigenesis are largely aimed at risk assessment and do not include explicit genetic information beyond group level but integrate many component processes, such as signalling, membrane permeability and metabolic activity. In this paper we present a scheme for modelling neurotoxin production in C. botulinum Group I type A1, based on the integration of diverse information coming from experimental results available in the literature. Experiments show that production of BoNTs depends on the growth-phase and is under the control of positive and negative regulatory elements at the intracellular level. Toxins are released as large protein complexes and are associated with non-toxic components. Here, we systematically review and integrate those regulatory elements previously described in the literature for C. botulinum Group I type A1 into a population dynamics model, to build the very first computational model of toxin production at the molecular level. We conduct a validation of our model against several items of published experimental data for different wild type and mutant strains of C. botulinum Group I type A1. The result of this process underscores the potential of mathematical modelling at the cellular level, as a means of creating opportunities in developing new strategies that could be used to prevent botulism; and potentially contribute to improved methods for the production of toxin that is used for therapeutics.

CAREER opportunities at the Condensed Matter Physics Program, NSF/DMR

NASA Astrophysics Data System (ADS)

Durakiewicz, Tomasz

The Faculty Early Career Development (CAREER) Program is a Foundation-wide activity, offering prestigious awards in support of junior faculty. Awards are expected to build the careers of teacher-scholars through outstanding research, excellent education and the integration of education and research. Condensed Matter Physics Program receives between 35 and 45 CAREER proposals each year, in areas related to fundamental research of phenomena exhibited by condensed matter systems. Proposal processing, merit review process, funding levels and success rates will be discussed in the presentation. NSF encourages submission of CAREER proposals from junior faculty members from CAREER-eligible organizations and encourages women, members of underrepresented minority groups, and persons with disabilities to apply. NSF/DMR/CMP homepage: https://www.nsf.gov/funding/pgm_summ.jsp?pims_id=5666

All-Optical Fibre Networks For Coal Mines

NASA Astrophysics Data System (ADS)

Zientkiewicz, Jacek K.

1987-09-01

A topic of the paper is fiber-optic integrated network (FOIN) suited to the most hostile environments existing in coal mines. The use of optical fibres for transmission of mine instrumentation data offers the prospects of improved safety and immunity to electromagnetic interference (EMI). The feasibility of optically powered sensors has opened up new opportunities for research into optical signal processing architectures. This article discusses a new fibre-optic sensor network involving a time domain multiplexing(TDM)scheme and optical signal processing techniques. The pros and cons of different FOIN topologies with respect to coal mine applications are considered. The emphasis has been placed on a recently developed all-optical fibre network using spread spectrum code division multiple access (COMA) techniques. The all-optical networks have applications in explosive environments where electrical isolation is required.

Reconstruction of fire regimes through integrated paleoecological proxy data and ecological modeling.

PubMed

Iglesias, Virginia; Yospin, Gabriel I; Whitlock, Cathy

2014-01-01

Fire is a key ecological process affecting vegetation dynamics and land cover. The characteristic frequency, size, and intensity of fire are driven by interactions between top-down climate-driven and bottom-up fuel-related processes. Disentangling climatic from non-climatic drivers of past fire regimes is a grand challenge in Earth systems science, and a topic where both paleoecology and ecological modeling have made substantial contributions. In this manuscript, we (1) review the use of sedimentary charcoal as a fire proxy and the methods used in charcoal-based fire history reconstructions; (2) identify existing techniques for paleoecological modeling; and (3) evaluate opportunities for coupling of paleoecological and ecological modeling approaches to better understand the causes and consequences of past, present, and future fire activity.

Tender Beginnings program: an educational continuum for the maternity patient.

PubMed

Brown, Susan E H

2006-01-01

The Tender Beginnings program demonstrates a comprehensive educational plan for maternity patients that can be extended throughout pregnancy, the birth process, and into the postpartum period. In today's healthcare environment, where the maternity patient continues to experience a shortened stay structure, the hurried learning process that is absorbed over a 48-hour stay is often ineffectual. This program provides a strategy and framework for effective teaching that can be successfully implemented all through the peripartum period. Budgetary constraints have given way to an innovative approach and opportunity for the healthcare specialist to explore an entrepreneurial relationship within the structure of the program. The Tender Beginnings program has proven to be a true integration of community educational outreach, nurse entrepreneurship, hospital-based education, and postpartum/neonatal follow-up.