Laser Pyro System Standardization and Man Rating

NASA Technical Reports Server (NTRS)

Brown, Christopher W.

2004-01-01

This viewgraph presentation reviews an X-38 laser pyro system standardization system designed for a new manned rated program. The plans to approve this laser initiation system and preliminary ideas for this system are also provided.

Pyro-cumulonimbus injection of smoke to the stratosphere: Observations and impact of a super blowup in northwestern Canada on 3-4 August 1998

NASA Astrophysics Data System (ADS)

Fromm, Michael; Bevilacqua, Richard; Servranckx, René; Rosen, James; Thayer, Jeffrey P.; Herman, Jay; Larko, David

2005-04-01

We report observations and analysis of a pyro-cumulonimbus event in the midst of a boreal forest fire blowup in Northwest Territories Canada, near Norman Wells, on 3-4 August 1998. We find that this blowup caused a five-fold increase in lower stratospheric aerosol burden, as well as multiple reports of anomalous enhancements of tropospheric gases and aerosols across Europe 1 week later. Our observations come from solar occultation satellites (POAM III and SAGE II), nadir imagers (GOES, AVHRR, SeaWiFS, DMSP), TOMS, lidar, and backscattersonde. First, we provide a detailed analysis of the 3 August eruption of extreme pyro-convection. This includes identifying the specific pyro-cumulonimbus cells that caused the lower stratospheric aerosol injection, and a meteorological analysis. Next, we characterize the altitude, composition, and opacity of the post-convection smoke plume on 4-7 August. Finally, the stratospheric impact of this injection is analyzed. Satellite images reveal two noteworthy pyro-cumulonimbus phenomena: (1) an active-convection cloud top containing enough smoke to visibly alter the reflectivity of the cloud anvil in the Upper Troposphere Lower Stratosphere (UTLS) and (2) a smoke plume, that endured for at least 2 hours, atop an anvil. The smoke pall deposited by the Norman Wells pyro-convection was a very large, optically dense, UTLS-level plume on 4 August that exhibited a mesoscale cyclonic circulation. An analysis of plume color/texture from SeaWiFS data, aerosol index, and brightness temperature establishes the extreme altitude and "pure" smoke composition of this unique plume. We show what we believe to be a first-ever measurement of strongly enhanced ozone in the lower stratosphere mingled with smoke layers. We conclude that two to four extreme pyro-thunderstorms near Norman Wells created a smoke injection of hemispheric scope that substantially increased stratospheric optical depth, transported aerosols 7 km above the tropopause (above ˜430 K potential temperature), and also perturbed lower stratospheric ozone.

The Hemisphere-scale Stratospheric Impact of the Chisholm (Alberta) PyroCumulonimbus Eruption

NASA Astrophysics Data System (ADS)

Fromm, M.; Barnes, J.; Blum, U.; Diner, D.; Fricke, K. H.; Gerding, M.; Giehl, H.; Kahn, R.; Lablanc, T.; Massie, S.; Stuart, M.; O'Neill, M.; Ritter, C.; Servranckx, R.; Shettle, E.; Torres, O.; Trickl, T.

2006-12-01

Extreme pyrocumulonimbus (pyroCb) blowups that polluted the lower stratosphere with smoke and other biomass burning emissions have been documented in the literature to have occurred on at least five separate occasions. However our understanding of the frequency and scale of these events is still far from complete. One pyroCb case study in the literature, the Chisholm Fire in Alberta in May 2001, was restricted to the convective phase and its immediate aftermath (Fromm and Servranckx, Geophys. Res. Lett., 2003). Here we describe the stratospheric impact of the Chisholm pyroCb. We present nadir and imaging satellite views of the post-pyroCb plume by the Multi-angle Imaging Spectroradiometer (MISR), Moderate Resolution Imaging Spectroradiomenter (MODIS), Total Ozone Mapping Spectrometer (TOMS), and a broad array of profile measurements, space- and ground-based. These include the Polar Ozone and Aerosol Measurement (POAM) III, Stratospheric Aerosol and Gas Experiment (SAGE) II, Halogen Occultation Experiment (HALOE), and seven ground-based lidars. We report that the Chisholm pyroCb was the singular cause of a hemispheric stratospheric aerosol increase in northern spring/summer of 2001. The smoke plume on the day after the pyro-eruption reached heights of 15 km, 4 km above the tropopause, was optically opaque at the tropopause, and caused unprecedented, large values of TOMS aerosol index. This plume eventually resulted in a doubling of zonal-average aerosol optical depth in the stratospheric middleworld and overworld. The meridional spread of the plume is confirmed from the tropics (20°N) to the high Arctic (79°N) within the first month. The stratospheric Chisholm smoke became a hemispheric phenomenon in midlatitudes and persisted for at least three months there and in the northern tropics. This work contains the first reported stratospheric smoke layers measured by lidar at Ny Älesund, Kühlungsborn, Garmisch Partenkirchen, Boulder, and Mauna Loa, and the second such reports from the Esrange lidar.

Voyager: Vibration Acoustics and Pyro Shock Testing

NASA Image and Video Library

2017-07-05

An engineer works on vibration acoustics and pyro shock testing for one of NASA's Voyager spacecraft on November 18, 1976. Several of the spacecraft's science instruments are visible at left. https://photojournal.jpl.nasa.gov/catalog/PIA21733

Smoking Pyrocumulonimbus: analysis of a major Canadian boreal fire blowup from satellite and ground measurements

NASA Astrophysics Data System (ADS)

Stocks, B. J.; Fromm, M.; Servranckx, R.; Miller, S.; Turk, J.; Diner, D.

2005-12-01

On 17 August 2003 a high-intensity forest fire close to the border of northern Alberta and the Northwest Territories in northwestern Canada exploded into a pyrocumulonimbus (pyroCb for short). PyroCb have in recent years been confirmed as an agent for transport of biomass burning emissions deeply into the lower stratosphere. The blowup was spawned by the Conibear Lake Fire, burning in the Wood Buffalo National Park (the largest boreal park in the world), where large fires are common/natural and seldom suppressed directly. The Conibear Lake Fire pyroCb created a plume of smoke that, on 18 August, was an optically opaque plume spanning from the lower troposphere to the lower stratosphere. A remarkable distinction of the pyroCb was that it grew to convective maturity during midday, enabling four true-color sensors (SeaWiFS, MISR, Terra MODIS, and Aqua MODIS) to observe the growth and spread of the tropopause-level anvil-and the anvil was smoky in color throughout. In this paper we will give a multiple nadir-viewer description of the entire life cycle of this pyroconvection. In addition to the unique smoky composition of the mature pyroCb, we will show the fire hot spot evolution, the cloud-top changes in terms of IR brightness temperature, an analysis of the cloud top altitude, and the deposition/advection of the smoke pall during and after convection. We will complement the satellite analysis with several ground-based indicators of fuel consumption, spread rates, energy release rates, and convection column dynamics that support the satellite observations of the pyroCb development.

Manipulation of novel nano-prodrug composed of organic pigment-based hybrid network and its optical uses.

PubMed

Zhou, Zhan; Zheng, Yuhui; Cheng, Cheng Zhang; Wen, Jiajia; Wang, Qianming

2017-01-01

Here we developed the first case of pyropheophorbide-a-loaded PEGylated-hybrid carbon nanohorns (CNH-Pyro) to study tumor targeting therapy. During incubation with living cells, CNH-Pyro exhibited very intense red emissions. The intracellular imaging results were carried out by flow cytometry based on four different kinds of cell lines (including three adherent cell lines and one suspension cell line). Compared with free pyropheophorbide-a, CNH-Pyro demonstrated enhanced photodynamic tumor ablation efficiency during in vitro experiments due to improved biocompatibility of the hybrid nanomaterial and the photothermal therapy effect derived from carbon-network structure. Trypan blue staining experiments supported that the cell fate was dependent on the synergistic effects of both CNH-Pyro and laser irradiations. These results indicated that the chlorin-entrapped carbon nanohorns could provide powerful delivery vehicles for increasing photodynamic efficacy and possess early identification of the disease. Copyright © 2016 Elsevier B.V. All rights reserved.

Real-time human versus animal classification using pyro-electric sensor array and Hidden Markov Model

NASA Astrophysics Data System (ADS)

Hossen, Jakir; Jacobs, Eddie L.; Chari, Srikant

2014-03-01

In this paper, we propose a real-time human versus animal classification technique using a pyro-electric sensor array and Hidden Markov Model. The technique starts with the variational energy functional level set segmentation technique to separate the object from background. After segmentation, we convert the segmented object to a signal by considering column-wise pixel values and then finding the wavelet coefficients of the signal. HMMs are trained to statistically model the wavelet features of individuals through an expectation-maximization learning process. Human versus animal classifications are made by evaluating a set of new wavelet feature data against the trained HMMs using the maximum-likelihood criterion. Human and animal data acquired-using a pyro-electric sensor in different terrains are used for performance evaluation of the algorithms. Failures of the computationally effective SURF feature based approach that we develop in our previous research are because of distorted images produced when the object runs very fast or if the temperature difference between target and background is not sufficient to accurately profile the object. We show that wavelet based HMMs work well for handling some of the distorted profiles in the data set. Further, HMM achieves improved classification rate over the SURF algorithm with almost the same computational time.

Pyro thruster for performing rocket booster attachment, disconnect, and jettison functions

NASA Technical Reports Server (NTRS)

Hornyak, Stephen

1989-01-01

The concept of a pyro thruster, combining an automatic structural attachment with quick disconnect and thrusting capability, is described. The purpose of the invention is to simplify booster installation, disengagement, and jettison functions for the U.S. Air Force Advanced Launch Systems (ALS) program.

Development of a solid-phase extraction method for determination of pheophorbide a and pyropheophorbide a in health foods by liquid chromatography.

PubMed

Oshima, Harumi; Ueno, Eiji; Saito, Isao; Matsumoto, Hiroshi

2004-01-01

A simple solid-phase extraction (SPE) method was developed for the liquid chromatography (LC) determination of pheophorbide (Phor) a and pyropheophorbide (Pyro) a in health foods such as chlorella, spirulina, etc. The food sample was extracted with 85% (v/v) acetone. The extract was acidified with hydrochloric acid and loaded on a C18 cartridge. After washing with water, Phor a and Pyro a were eluted with the LC mobile phase. Phor a and Pyro a were separated by isocratic reversed-phase LC and quantitated by fluorescence detection. The recoveries for spiked samples of chlorella and the extract were 87.1-102.0%. Commercial health foods (chlorella, spirulina, aloe, kale, Jews mallow, and green tea leaves) were analyzed using the SPE method. The values found for Phor a and Pyro a ranged from 2 to 788 microg/g and from <1 to 24 microg/g, respectively. There was no significant difference between the SPE method and the official method in Japan (spectrophotometry after liquid-liquid extraction). The advantages of the SPE method are the short extraction times, lack of emulsions, and reduced consumption of organic solvents compared with the official method in Japan. The SPE method is considered to be useful for the screening of Phor a and Pyro a in health foods.

Polar Pollution by Pyroconvection: Assessing the transport of smoke into the Arctic and Antarctic

NASA Astrophysics Data System (ADS)

Fromm, M. D.; Stocks, B. J.; Hoff, R.

2007-12-01

In northern summer of 2007 boreal forest fires erupted into pyrocumulonimbus (pyroCb) on two continents and injected substantial amounts of smoke into the upper troposphere and lower stratosphere (UTLS). Some of this smoke was transported into high Arctic latitudes where it was observed by ground and space-based instruments. In the Austral summer of 2006/2007 an extremely intense pyroCb in Victoria Australia also polluted the UTLS, from tropical to Antarctic latitudes. This wide-ranging influence of a "small", discrete event such as a fire-aided thunderstorm implies that the pyroCb's weather and climate context needs to be much better understood. Here we will present two case studies from the above-mentioned seasons. The Austral case will include an analysis of the immediate post-blowup smoke plume as observed by MODIS imagery and OMI aerosol index (AI). Then the plume will be followed as it circles the globe and spreads to meridional extremes using AI, CALIPSO backscatter, and geostationary satellite visible imagery. The boreal study will summarize the notable pyroCbs of 2007. One of these was in Mongolia, the first such unambiguously determined Asian pyroCb. The main focus of this analysis will on the observations of stratospheric smoke subsequent to these blowups in midlatitudes observed by CALIPSO, and Arctic smoke observed by both CALIPSO and ground-based lidar at Eureka.

Laser-initiated ordnance for air-to-air missiles

NASA Technical Reports Server (NTRS)

Sumpter, David R.

1993-01-01

McDonnell Douglas Missile Systems Company (MDMSC) has developed a laser ignition subsystem (LIS) for air-to-air missile applications. The MDMSC subsystem is designed to activate batteries, unlock fins, and sequence propulsion system events. The subsystem includes Pyro Zirconium Pump (PZP) lasers, mechanical Safe & Arm, fiber-optic distribution system, and optically activated pyrotechnic devices (initiators, detonators, and thermal batteries). The LIS design has incorporated testability features for the laser modules, drive electronics, fiber-optics, and pyrotechnics. Several of the LIS have been fabricated and have supported thermal battery testing, integral rocket ramjet testing, and have been integrated into integral rocket ramjet flight test vehicles as part of the flight control subsystem.

Peptide-based pharmacomodulation of a cancer-targeted optical imaging and photodynamic therapy agent

PubMed Central

Stefflova, Klara; Li, Hui; Chen, Juan; Zheng, Gang

2008-01-01

We designed and synthesized a folate receptor-targeted, water soluble, and pharmacomodulated photodynamic therapy (PDT) agent that selectively detects and destroys the targeted cancer cells while sparing normal tissue. This was achieved by minimizing the normal organ uptake (e.g., liver and spleen) and by discriminating between tumors with different levels of folate receptor (FR) expression. This construct (Pyro-peptide-Folate, PPF) is comprised of three components: 1) Pyropheophorbide a (Pyro) as an imaging and therapeutic agent, 2) peptide sequence as a stable linker and modulator improving the delivery efficiency, and 3) Folate as a homing molecule targeting FR-expressing cancer cells. We observed an enhanced accumulation of PPF in KB cancer cells (FR+) compared to HT 1080 cancer cells (FR-), resulting in a more effective post-PDT killing of KB cells over HT 1080 or normal CHO cells. The accumulation of PPF in KB cells can be up to 70% inhibited by an excess of free folic acid. The effect of Folate on preferential accumulation of PPF in KB tumors (KB vs. HT 1080 tumors 2.5:1) was also confirmed in vivo. In contrast to that, no significant difference between the KB and HT 1080 tumor was observed in case of the untargeted probe (Pyro-peptide, PP), eliminating the potential influence of Pyro’s own nonspecific affinity to cancer cells. More importantly, we found that incorporating a short peptide sequence considerably improved the delivery efficiency of the probe – a process we attributed to a possible peptide-based pharmacomodulation – as was demonstrated by a 50-fold reduction in PPF accumulation in liver and spleen when compared to a peptide-lacking probe (Pyro-K-Folate, PKF). This approach could potentially be generalized to improve the delivery efficiency of other targeted molecular imaging and photodynamic therapy agents. PMID:17298029

Pyro: A Python-Based Versatile Programming Environment for Teaching Robotics

ERIC Educational Resources Information Center

Blank, Douglas; Kumar, Deepak; Meeden, Lisa; Yanco, Holly

2004-01-01

In this article we describe a programming framework called Pyro, which provides a set of abstractions that allows students to write platform-independent robot programs. This project is unique because of its focus on the pedagogical implications of teaching mobile robotics via a top-down approach. We describe the background of the project, its…

pyro: Python-based tutorial for computational methods for hydrodynamics

NASA Astrophysics Data System (ADS)

Zingale, Michael

2015-07-01

pyro is a simple python-based tutorial on computational methods for hydrodynamics. It includes 2-d solvers for advection, compressible, incompressible, and low Mach number hydrodynamics, diffusion, and multigrid. It is written with ease of understanding in mind. An extensive set of notes that is part of the Open Astrophysics Bookshelf project provides details of the algorithms.

The use of witness trees as pyro-indicators for mapping past fire conditions

Treesearch

Melissa A. Thomas-Van Gundy; Gregory J. Nowacki

2013-01-01

Understanding and mapping presettlement fire regimes is vitally important for ecosystem restoration, helping ensure the proper placement of fire back into ecosystems that formerly burned. Witness trees can support this endeavor by serving as pyro-indicators of the past. We mapped fire-adapted traits across a landscape by categorizing trees into two classes, pyrophiles...

Real-time monitoring of thermodynamic microenvironment in a pan coater.

PubMed

Pandey, Preetanshu; Bindra, Dilbir S

2013-02-01

The current study demonstrates the use of tablet-size data logging devices (PyroButtons) to quantify the microenvironment experienced by tablets during pan coating process. PyroButtons were fixed at the inlet and exhaust plenums, and were also placed to freely move with the tablets. The effects of process parameters (spray rate and inlet-air humidity) on the thermodynamic conditions inside the pan coater were studied. It was shown that the same exhaust temperature (a parameter most commonly monitored and controlled during film coating) can be attained with very different tablet-bed conditions. The tablet-bed conditions were found to be more sensitive to the changes in spray rate as compared with the inlet-air humidity. Both spray rate and inlet-air humidity were shown to have an effect on the number of tablet defects (loss of logo definition), and a good correlation between number of tablet defects and tablet-bed humidity was observed. The ability to quantify the thermodynamic microenvironment experienced by the tablets during coating and be able to correlate that to macroscopic tablet defects can be an invaluable tool that can help to establish a process design space during product development. Copyright © 2012 Wiley Periodicals, Inc.

Intramolecular trap formation and Förster energy transfer in the hexapyropheophorbide- a molecular system

NASA Astrophysics Data System (ADS)

Al-Omari, S.

2006-12-01

The photophysical properties of the hexapyropheophorbide- a (P6) compound were studied using both steady-state and time-resolved spectroscopy. It was found that neighboring pyropheophorbide- a (pyroPheo) molecules covalently linked to each other through carbon chains, which could stack. This structural property is the reason for the possibility of formation of two different types of energy traps, which could be resolved experimentally. One of them is formed via face-to-face stacking of two pyroPheo molecules with a direction of the transition dipole moments parallel to each other. The second type of energy trap gives the dominant contribution to the fluorescence signal at a registration wavelength having the oblique geometry or orthogonal direction of the transition dipole moments of the interacting pyroPheo molecules. In any case, the dipole-dipole Förster energy transfer between pyroPheo molecules caused a very fast and efficient delivery of the excitation to a trap. As a result, the fluorescence as well as the singlet oxygen quantum yields of P6 were reduced by four and three times, respectively, compared to those values of the reference bispyrophephorbide- a (P2) compound.

In-vial pyrolysis (PyroVial) with pre- and post-sample treatment combined with different chromatographic techniques.

PubMed

Tienpont, Bart; David, Frank; Pereira, Alberto; Sandra, Pat

2011-11-18

A new generic pyrolysis unit (PyroVial) is presented. Pyrolysis is carried out in a 2 mL autosampler vial placed in a XYZ robot for automated pyrolysis as well as for pre- and post-pyrolysis treatment of the sample. Analysis of the volatiles is performed by headspace analysis while the semi- and non-volatiles are extracted from the pyrolysate with an organic solvent. The features of the PyroVial are such that all chromatographic techniques can be applied. The pyrolysis unit is discussed in terms of its technical features and its performance is illustrated with applications including conventional pyrolysis, in situ and post-pyrolysis derivatization, reaction pyrolysis and catalytic cracking. Copyright © 2011 Elsevier B.V. All rights reserved.

Photophysical properties of fullerene-dendron-pyropheophorbide supramolecules

NASA Astrophysics Data System (ADS)

Ermilov, E. A.; Al-Omari, S.; Helmreich, M.; Jux, N.; Hirsch, A.; Röder, B.

2004-05-01

Two novel monofullerene-bis(pyropheophorbide a) complexes were synthesized and their photophysical properties were studied by using both steady-state and time-resolved techniques. It was revealed that in the pyropheophorbide a (pyroPheo)-C 60 molecular system (FP1) strong quenching of the first excited singlet state of the pyroPheo and, as result, dramatically decreasing of photosensitized singlet oxygen generation occurs by efficient photoinduced electron transfer to the fullerene molecule with a rate constant of 2.5 × 10 9 s -1. In contrast, the fullerene hexaadduct-bis(pyroPheo) system (FHP1), which possesses five diethyl malonate addends in the remaining octahedral positions, shows a high singlet oxygen quantum yield which is due to the reduced fullerene chromophore which is not a good electron acceptor anymore.

Separation of Lead from Crude Antimony by Pyro-Refining Process with NaPO3 Addition

NASA Astrophysics Data System (ADS)

Ye, Longgang; Hu, Yuejie; Xia, Zhimei; Chen, Yongming

2016-06-01

The main purpose of this study was to separate lead from crude antimony through an oxidation pyro-refining process and by using sodium metaphosphate as a lead elimination reagent. The process parameters that will affect the refining results were optimized experimentally under controlled conditions, such as the sodium metaphosphate charging dosage, the refining temperature and duration, and the air flow rate, to determine their effect on the lead content in refined antimony and the lead removal rate. A minimum lead content of 0.0522 wt.% and a 98.6% lead removal rate were obtained under the following optimal conditions: W_{{{NaPO}_{{3}} }} = 15% W Sb (where W represents weight), a refining temperature of 800°C, a refining time of 30 min, and an air flow rate of 3 L/min. X-ray diffractometry and scanning electron microscopy showed that high-purity antimony was obtained. The smelting operation is free from smoke or ammonia pollution when using monobasic sodium phosphate or ammonium dihydrogen phosphate as the lead elimination reagent. However, this refining process can also remove a certain amount of sulfur, cobalt, and silicon simultaneously, and smelting results also suggest that sodium metaphosphate can be used as a potential lead elimination reagent for bismuth and copper refining.

Multiplex pyrosequencing assay using AdvISER-MH-PYRO algorithm: a case for rapid and cost-effective genotyping analysis of prostate cancer risk-associated SNPs.

PubMed

Ambroise, Jérôme; Butoescu, Valentina; Robert, Annie; Tombal, Bertrand; Gala, Jean-Luc

2015-06-25

Single Nucleotide Polymorphisms (SNPs) identified in Genome Wide Association Studies (GWAS) have generally moderate association with related complex diseases. Accordingly, Multilocus Genetic Risk Scores (MGRSs) have been computed in previous studies in order to assess the cumulative association of multiple SNPs. When several SNPs have to be genotyped for each patient, using successive uniplex pyrosequencing reactions increases analytical reagent expenses and Turnaround Time (TAT). While a set of several pyrosequencing primers could theoretically be used to analyze multiplex amplicons, this would generate overlapping primer-specific pyro-signals that are visually uninterpretable. In the current study, two multiplex assays were developed consisting of a quadruplex (n=4) and a quintuplex (n=5) polymerase chain reaction (PCR) each followed by multiplex pyrosequencing analysis. The aim was to reliably but rapidly genotype a set of prostate cancer-related SNPs (n=9). The nucleotide dispensation order was selected using SENATOR software. Multiplex pyro-signals were analyzed using the new AdvISER-MH-PYRO software based on a sparse representation of the signal. Using uniplex assays as gold standard, the concordance between multiplex and uniplex assays was assessed on DNA extracted from patient blood samples (n = 10). All genotypes (n=90) generated with the quadruplex and the quintuplex pyroquencing assays were perfectly (100 %) concordant with uniplex pyrosequencing. Using multiplex genotyping approach for analyzing a set of 90 patients allowed reducing TAT by approximately 75 % (i.e., from 2025 to 470 min) while reducing reagent consumption and cost by approximately 70 % (i.e., from ~229 US$ /patient to ~64 US$ /patient). This combination of quadruplex and quintuplex pyrosequencing and PCR assays enabled to reduce the amount of DNA required for multi-SNP analysis, and to lower the global TAT and costs of SNP genotyping while providing results as reliable as uniplex analysis. Using this combined multiplex approach also substantially reduced the production of waste material. These genotyping assays appear therefore to be biologically, economically and ecologically highly relevant, being worth to be integrated in genetic-based predictive strategies for better selecting patients at risk for prostate cancer. In addition, the same approach could now equally be transposed to other clinical/research applications relying on the computation of MGRS based on multi-SNP genotyping.

Atmosphere-fire simulation of effects of low-level jets on pyro-convective plume dynamics

Treesearch

Colin C. Simpson; Marwan Katurji; Michael T. Kiefer; Shiyuan Zhong; Joseph J. Charney; Warren E. Heilman; Xindi Bian

2013-01-01

Blow-up fire behaviour can be broadly defined as a rapid escalation in the intensity or forward rate of spread of a wildland fire, and is often accompanied by extreme pyro-convection associated with rapid smoke release and dispersion. Blow-up fire behaviour is difficult to predict and has been linked to firefighter fatalities, making it an important fire management...

Three-dimensional imaging of the metabolic state of c-MYC-induced mammary tumor with the cryo-imager

NASA Astrophysics Data System (ADS)

Zhang, Zhihong; Liu, Qian; Luo, Qingming; Zhang, Min Z.; Blessington, Dana M.; Zhou, Lanlan; Chodosh, Lewis A.; Zheng, Gang; Chance, Britton

2003-07-01

This study imaged the metabolic state of a growing tumor and the relationship between energy metabolism and the ability of glucose uptake in whole tumor tissue with cryo-imaging at 77° K. A MTB/TOM mouse model, bearing c-MYC-induced mammary tumor, was very rapidly freeze-trapped 2 hrs post Pyro-2DG injection. The fluorescence signals of oxidized flavoprotein (Fp), reduced pyridine nucleotide (PN), pyro-2DG, and the reflection signal of deoxy-hemoglobin were imaged every 100 μm from the top surface to the bottom of the tumor sequentially, 9 sections in total. Each of the four signals was constructed into 3D images with Amira software. Both Fp and PN signals could be detected in the growing tumor regions, and a higher reduction state where was shown in the ratio images. The necrotic tumor regions displayed a very strong Fp signal and weak PN signal. In the bloody extravasation regions, Fp and PN signals were observably diminished. Therefore, the regions of high growth and necrosis in the tumor could be determined according to the Fp and PN signals. The content of deoxy-hemoglobin (Hb) in the tumor was positively correlated with the reduced PN signal. Pyro-2DG signal was only evident in the growing condition region in the tumor. Normalized 3D cross-correlation showed that Pyro-2DG signal was similar to the redox ratio. The results indicated that glucose uptake in the tumor was consistent with the redox state of the tumor. And both Pyro-2DG and mitochondrial NADH fluorescence showed bimodal histograms suggesting that the two population of c-MYC induced mammary tumor, one of which could be controlled by c-MYC transgene.

Pyropheophorbide 2-deoxyglucosamide: a new photosensitizer targeting glucose transporters.

PubMed

Zhang, Min; Zhang, Zhihong; Blessington, Dana; Li, Hui; Busch, Theresa M; Madrak, Vanessa; Miles, Jeremy; Chance, Britton; Glickson, Jerry D; Zheng, Gang

2003-01-01

To prepare near-infrared fluorescence imaging and photodynamic therapy agents targeted at glucose transporters, pyropheophorbide 2-deoxyglucosamide (Pyro-2DG) was synthesized and evaluated in a 9L glioma rat model. Fluorescence imaging studies demonstrate that Pyro-2DG is selectively accumulated in the tumor. Upon its photoactivation, we demonstrate that this agent efficiently causes selective mitochondrial damage to the region of a tumor that was photoirradiated after administration of this agent, but does not affect tissues photoirradiated in the absence of the agent or tissues treated with the agent that are not photoirradiated. Preliminary confocal microscopy studies suggest that Pyro-2DG is delivered and trapped in tumor cells via the GLUT/hexokinase pathway and therefore is useful both as a tumor-targeted NIR fluorescence imaging probe and as a PDT agent for the destruction of cancer.

PROCESS FOR THE RECOVERY OF METALS FROM HIGH-LIME CARNOTITE ORES

DOEpatents

Grinstead, R.R.

1959-01-20

A process is presented for recovering uranium values from a high-lime carnotite ore comprising contacting the ore dispersed in a finely divided state with a concentrated mineral acid, adding an industrial orgnnic solvent containing alkyl ontho or pyro phosphoric acids, alkyl phosphates or alkyl phosphonates so as to effect an organic phase into which the metal value is leached and then recovering the metal value from the organic phase.

Trap formation and energy transfer in the hexapyropheophorbide a - fullerene C 60 hexaadduct molecular system

NASA Astrophysics Data System (ADS)

Ermilov, E. A.; Hackbarth, St.; Al-Omari, S.; Helmreich, M.; Jux, N.; Hirsch, A.; Röder, B.

2005-06-01

The photophysical properties of the novel hexapyropheophorbide a - fullerene hexaadduct (FHP6) compound were studied using both steady-state and time-resolved spectroscopic methods. It was found that neighboring pyropheophorbide a (pyroPheo) molecules covalently linked to one fullerene moiety due to the length and high flexibility of carbon chains could stack with each other. This structural property is the reason for the possibility of formation of two different types of energy traps, which could be resolved experimentally. One of them is formed via face-to-face stacking of two pyroPheo molecules with parallel to each other direction of the transition dipole moments. The second type of energy trap gives the dominant contribution to the fluorescence signal at registration wavelengths having the oblique geometry or orthogonal direction of the transition dipole moments of the interacting pyroPheo molecules. In any case the dipole-dipole resonant Förster energy transfer between pyroPheo molecules coupled to one fullerene moiety caused a very fast and efficient delivery of the excitation to a trap. As result the fluorescence as well as the singlet oxygen quantum yields of FHP6 were reduced three and two times, respectively, compared to those values of the reference bis pyropheophorbide a - fullerene hexaadduct (FHP1) compound.

The development of pyro shock test requirements for Viking Lander Capsule components

NASA Technical Reports Server (NTRS)

Barrett, S.

1975-01-01

The procedure used to derive component-level pyro shock specifications for the Viking Lander Capsule (VLC) is described. Effects of shock path distance and mechanical joints between the device and the point at which the environment is to be estimated are accounted for in the method. The validity of the prediction technique was verified by a series of shock tests on a full-scale structural model of the lander body.

Quantitative Phase Microscopy for Accurate Characterization of Microlens Arrays

NASA Astrophysics Data System (ADS)

Grilli, Simonetta; Miccio, Lisa; Merola, Francesco; Finizio, Andrea; Paturzo, Melania; Coppola, Sara; Vespini, Veronica; Ferraro, Pietro

Microlens arrays are of fundamental importance in a wide variety of applications in optics and photonics. This chapter deals with an accurate digital holography-based characterization of both liquid and polymeric microlenses fabricated by an innovative pyro-electrowetting process. The actuation of liquid and polymeric films is obtained through the use of pyroelectric charges generated into polar dielectric lithium niobate crystals.

Changing the Rules on Fuel Export at Sellafield's First Fuel Storage Pond - 12065

DOE Office of Scientific and Technical Information (OSTI.GOV)

Carlisle, Derek

2012-07-01

The Pile Fuel Storage Pond (PFSP) was built in 1949/50 to receive, store and de-can fuel and isotopes from the Windscale Piles. Following closure of the Piles in 1957, plant operations were scaled down until fuel processing eventually ceased in 1962. The facility has held an inventory of metal fuel both from the Piles and from other programmes since that time. The pond is currently undergoing remediation and removal of the fuel is a key step in that process, unfortunately the fuel export infrastructure on the plant is no longer functional and due to the size and limited lifting capability,more » the plant is not compatible with today's large volume heavy export flasks. The baseline scheme for the plant is to package fuel into a small capacity flask and transfer it to another facility for treatment and repackaging into a flask compatible with other facilities on site. Due to programme priorities the repackaging facility is not available to do this work for several years causing a delay to the work. In an effort accelerate the programme the Metal Fuel Pilot Project (MFPP) was initiated to challenge the norms for fuel transfer and develop a new methodology for transferring the fuel. In developing a transfer scheme the team had to overcome challenges associated with unknown fuel condition, transfers outside of bulk containment, pyro-phoricity and oxidisation hazards as well as developing remote control and recovery systems for equipment not designed for this purpose. A combination of novel engineering and enhanced operational controls were developed which resulted in the successful export of the first fuel to leave the Pile Fuel Storage Pond in over 40 years. The learning from the pilot project is now being considered by the main project team to see how the new methodology can be applied to the full inventory of the pond. (author)« less

Reducing/Eliminating ESD Hazards During Pyro Operations

NASA Technical Reports Server (NTRS)

Soriano, Jose Francisco; Kelley, J. D. (Technical Monitor)

2001-01-01

Several safety concerns have occurred during pyro operations at 30% or lower RH in the OPF area based on the increase of electrostatic discharge (ESD). These concerns targeted the safety of personnel, flight hardware, and ground support equipment (GSE). Two proposed methods considered to control ESDs during pyro operations at 30% or lower RH are the use of an ionizer blower and to increase the moisture content. In order to demonstrate that the ionizer is effective in neutralizing static charge, a series of experimental runs were conducted in the Electrostatics Laboratory located in the Operations & Checkout (O&C) Building at NASA Kennedy Space Center (KSC). The effectiveness of the ionizer blower was evaluated based upon the time lapse of a charged metal plate from initial 1000 to 400 volts. Distance, RH, and angle of attack were studied. A full factorial experiment (2(exp 3) = 8) was conducted. Since we did not have a statistical analysis program, such as SAS, available, calculations were done manually based on the method of ANOVA (Analysis of Variances), but R(exp 2) (fitness of curve) was not obtained. As conjectured, distance was found to be the major influencial variable. Therefore, we concluded that the best possible combination of situations would be to position the ionizer blower as close as possible and facing directly into the charged plate. This scenario resulted in the quickest discharge rate, which would be the most beneficial during pyro operations below 30% RH. The second method of increasing the moisture content in the work environment through a modification of the OPF ECS current configuration appeared to be dependent on budget constraints and currently not planned to be modified. Finally, some recommendations are discussed such as to test the ionizer in an actual field experiment with a mockup pyro connector and a technician with all the NASA KSC Safety-compliant PPE to assess the realistic effectiveness of the ionizer blower.

Selective Pyroelectric Detection of Millimetre Waves Using Ultra-Thin Metasurface Absorbers

PubMed Central

Kuznetsov, Sergei A.; Paulish, Andrey G.; Navarro-Cía, Miguel; Arzhannikov, Andrey V.

2016-01-01

Sensing infrared radiation is done inexpensively with pyroelectric detectors that generate a temporary voltage when they are heated by the incident infrared radiation. Unfortunately the performance of these detectors deteriorates for longer wavelengths, leaving the detection of, for instance, millimetre-wave radiation to expensive approaches. We propose here a simple and effective method to enhance pyroelectric detection of the millimetre-wave radiation by combining a compact commercial infrared pyro-sensor with a metasurface-enabled ultra-thin absorber, which provides spectrally- and polarization-discriminated response and is 136 times thinner than the operating wavelength. It is demonstrated that, due to the small thickness and therefore the thermal capacity of the absorber, the detector keeps the high response speed and sensitivity to millimetre waves as the original infrared pyro-sensor does against the regime of infrared detection. An in-depth electromagnetic analysis of the ultra-thin resonant absorbers along with their complex characterization by a BWO-spectroscopy technique is presented. Built upon this initial study, integrated metasurface absorber pyroelectric sensors are implemented and tested experimentally, showing high sensitivity and very fast response to millimetre-wave radiation. The proposed approach paves the way for creating highly-efficient inexpensive compact sensors for spectro-polarimetric applications in the millimetre-wave and terahertz bands. PMID:26879250

Integration Process for Payloads in the Fluids and Combustion Facility

NASA Technical Reports Server (NTRS)

Free, James M.; Nall, Marsha M.

2001-01-01

The Fluids and Combustion Facility (FCF) is an ISS research facility located in the United States Laboratory (US Lab), Destiny. The FCF is a multi-discipline facility that performs microgravity research primarily in fluids physics science and combustion science. This facility remains on-orbit and provides accommodations to multi-user and Principal investigator (PI) unique hardware. The FCF is designed to accommodate 15 PI's per year. In order to allow for this number of payloads per year, the FCF has developed an end-to-end analytical and physical integration process. The process includes provision of integration tools, products and interface management throughout the life of the payload. The payload is provided with a single point of contact from the facility and works with that interface from PI selection through post flight processing. The process utilizes electronic tools for creation of interface documents/agreements, storage of payload data and rollup for facility submittals to ISS. Additionally, the process provides integration to and testing with flight-like simulators prior to payload delivery to KSC. These simulators allow the payload to test in the flight configuration and perform final facility interface and science verifications. The process also provides for support to the payload from the FCF through the Payload Safety Review Panel (PSRP). Finally, the process includes support in the development of operational products and the operation of the payload on-orbit.

Microwave processing of cement and concrete materials – towards an industrial reality?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Buttress, Adam, E-mail: adam.buttress@nottingham.ac.uk; Jones, Aled; Kingman, Sam

2015-02-15

Each year a substantial body of literature is published on the use of microwave to process cement and concrete materials. Yet to date, very few if any have lead the realisation of a commercial scale industrial system and is the context under which this review has been undertaken. The state-of the–art is evaluated for opportunities, and the key barriers to the development of new microwave-based processing techniques to enhance production, processing and recycling of cement and concrete materials. Applications reviewed include pyro-processing of cement clinker; accelerated curing, non-destructive testing and evaluation (NDT&E), and end-of-life processing including radionuclide decontamination.

Retrospective reconstruction of Iodine-131 distribution through the analysis of Iodine-129

NASA Astrophysics Data System (ADS)

Matsuzaki, Hiroyuki; Muramatsu, Yasuyuki; Ohno, Takeshi; Mao, Wei

2017-09-01

Iodine-131 distribution released from the Fukushima Dai-ichi Nuclear Power Plant accident was reconstructed through the iodine-129 measurements. From nearly 1,000 surface soil samples iodine was extracted by the pyro hydrolysis method. Extracted iodine was then mixed with carrier, purified and finally collected as silver iodide. Silver iodide sample was pressed into the cathode holder and set at the ion source of the MALT facility, The University of Tokyo. The isotopic ratio 129I/127I was measured by means of Accelerator Mass Spectrometry. From 129I data obtained, 131I deposition map was constructed. There observed various fine structures in the map which could not estimated neither by the simulation nor 137Cs distribution.

Towards Lead-Free Piezoceramics: Facing a Synthesis Challenge

PubMed Central

Villafuerte-Castrejón, María Elena; Morán, Emilio; Reyes-Montero, Armando; Vivar-Ocampo, Rodrigo; Peña-Jiménez, Jesús-Alejandro; Rea-López, Salvador-Oliver; Pardo, Lorena

2016-01-01

The search for electroceramic materials with enhanced ferro-pyro-piezoelectric properties and revealing the perovskite type structure has been the objective of a significant number of manuscripts reported in the literature. This has been usually carried out by proposing the synthesis and processing of new compounds and solid solution series. In this work, several methods to obtain ferro-pyro-piezoelectric families of materials featuring the well-known ABO3 perovskite structure (or related) such as BaTiO3, Ba1–xCaxTi1–yZryO3, (Bi0.5Na0.5)TiO3, (K0.5Na0.5)NbO3 and their solid solutions with different cations either in the A or B positions, are presented. For this kind of materials, the challenge for obtaining a single phase compound with a specific grain size and morphology and, most importantly, with the adequate stoichiometry, will also be discussed. The results reviewed herein will be discussed in terms of the tendency of working with softer conditions, i.e., lower temperature and shorter reaction times, also referred to as soft-chemistry. PMID:28787822

Thermal Storage Process and Components Laboratory | Energy Systems

Science.gov Websites

Integration Facility | NREL Process and Components Laboratory Thermal Storage Process and Components Laboratory The Energy Systems Integration Facility's Thermal Systems Process and Components Laboratory supports research and development, testing, and evaluation of new thermal energy storage systems

An Examination of Extreme Fire Behavior and its Impact on Smoke Injection Altitude using Remote Sensing and Meteorological Data

NASA Astrophysics Data System (ADS)

Peterson, D. A.; Hyer, E. J.; Campbell, J. R.; Fromm, M. D.; Hair, J. W.; Butler, C. F.; Fenn, M. A.

2014-12-01

A variety of regional smoke forecasting applications are currently available to identify air quality, visibility, and societal impacts during large fire events. However, these systems typically assume persistent fire activity, and therefore can have large errors before, during, and after short-term periods of extreme fire behavior. This study employs a wide variety of ground, airborne, and satellite observations, including data collected during a major NASA airborne and field campaign, to examine the conditions required for both extreme spread and pyrocumulonimbus (pyroCb) development. Results highlight the importance of upper-level and nocturnal meteorology, as well as the limitations of traditional fire weather indices. Increasing values of fire radiative power (FRP) at the pixel and sub-pixel level are shown to systematically correspond to higher altitude smoke plumes, and an increased probability of injection above the boundary layer. Lidar data collected during the 2013 Rim Fire, one of the most severe fire events in California's history, show that high FRP observed during extreme spread can facilitate long-distance smoke transport, but fails to loft smoke to the altitude of a large pyroCb. The most extreme fire spread was also observed on days without pyroCb activity or significant regional convection. By incorporating additional fire events across North America, conflicting hypotheses surrounding the primary source of moisture during pyroCb development are examined. The majority of large pyroCbs, and therefore the highest direct injection altitude of smoke particles, is shown to occur with conditions very similar to those that produce dry thunderstorms. The current suite of automated forecasting applications predict only general trends in fire behavior, and specifically do not predict (1) extreme fire spread events and (2) injection of smoke to high altitudes. While (1) and (2) are related, results show that they are not predicted by the same set of conditions and variables. The combination of meteorology from numerical forecast models and satellite observations exhibits great potential for improving regional forecasts of fire behavior and smoke production in automated systems, especially in remote areas where detailed observations are unavailable

Expression and purification of pheophorbidase, an enzyme catalyzing the formation of pyropheophorbide during chlorophyll degradation: comparison with the native enzyme.

PubMed

Suzuki, Yasuyo; Soga, Keiko; Yoshimatsu, Katsuhiko; Shioi, Yuzo

2008-10-01

Formation of pyropheophorbide (PyroPheid) during chlorophyll metabolism in some higher plants has been shown to involve the enzyme pheophorbidase (PPD). This enzyme catalyzes the conversion of pheophorbide (Pheid) a to a precursor of PyroPheid, C-13(2)-carboxylPyroPheid a, by demethylation, and then the precursor is decarboxylated non-enzymatically to yield PyroPheid a. In this study, expression, purification, and biochemical characterization of recombinant PPD from radish (Raphanus sativus L.) were performed, and its properties were compared with those of highly purified native PPD. Recombinant PPD was produced using a glutathione S-transferase (GST) fusion system. The PPD and GST genes were fused to a pGEX-2T vector and expressed in Escherichia coli under the control of a T7 promoter as a fusion protein. The recombinant PPD-GST was expressed as a 55 kDa protein as measured by SDS-PAGE and purified by single-step affinity chromatography through a GSTrap FF column. PPD-GST was purified to homogeneity with a yield of 0.42 mg L(-1) of culture. The protein purified by this method was confirmed to be PPD by measuring its activity. The purified PPD-GST fusion protein revealed potent catalytic activity for demethylation of the methoxycarbonyl group of Pheid a and showed a pH optimum, substrate specificity, and thermal stability quite similar to the native enzyme purified from radish, except for the Km values toward Pheid a: 95.5 microM for PPD-GST and about 15 microM for native PPDs.

Correlating bilayer tablet delamination tendencies to micro-environmental thermodynamic conditions during pan coating.

PubMed

Zacour, Brian M; Pandey, Preetanshu; Subramanian, Ganeshkumar; Gao, Julia Z; Nikfar, Faranak

2014-06-01

The objective of this study was to determine the impact that the micro-environment, as measured by PyroButton data loggers, experienced by tablets during the pan coating unit operation had on the layer adhesion of bilayer tablets in open storage conditions. A full factorial design of experiments (DOE) with three center points was conducted to study the impact of final tablet hardness, film coating spray rate and film coating exhaust temperature on the delamination tendencies of bilayer tablets. PyroButton data loggers were placed (fixed) at various locations in a pan coater and were also allowed to freely move with the tablet bed to measure the micro-environmental temperature and humidity conditions of the tablet bed. The variance in the measured micro-environment via PyroButton data loggers accounted for 75% of the variance in the delamination tendencies of bilayer tablets on storage (R(2 )= 0.75). A survival analysis suggested that tablet hardness and coating spray rate significantly impacted the delamination tendencies of the bilayer tablets under open storage conditions. The coating exhaust temperature did not show good correlation with the tablets' propensity to crack indicating that it was not representative of the coating micro-environment. Models created using data obtained from the PyroButton data loggers outperformed models created using primary DOE factors in the prediction of bilayer tablet strength, especially upon equipment or scale transfers. The coating micro-environment experienced by tablets during the pan coating unit operation significantly impacts the strength of the bilayer interface of tablets on storage.

Steady-state and time-resolved studies on the photophysical properties of fullerene-pyropheophorbide a complexes in polar and nonpolar solvents

NASA Astrophysics Data System (ADS)

Ermilov, E. A.; Al-Omari, S.; Helmreich, M.; Jux, N.; Hirsch, A.; Röder, B.

2004-04-01

A novel monofullerene-bis(pyropheophorbide a) dyad has been photophysically characterized by steady-state as well as time-resolved techniques. It was revealed that in this complex strong and fast quenching of the first excited singlet state of the pyropheophorbide a (pyroPheo) molecule occurs by efficient photoinduced electron transfer to the fullerene moiety in both polar (DMF) and nonpolar (toluene) solvents. In DMF the energy of the charge-separated state is 0.94 eV and it undergoes directly transition to the ground state resulting in a very low value of photosensitized singlet oxygen generation. In contrast to the situation in a polar solvent, in toluene the charge-separated state lies above the exited triplet state of pyroPheo as well as that of C 60. It has been shown that in a nonpolar solvent a sufficient amount of singlet oxygen was generated by energy transfer from the excited triplet state of pyroPheo which has been populated via relaxation of the charge-separated state.

Folic Acid-Conjugated Pyropheophorbide a as the Photosensitizer Tested for In Vivo Targeted Photodynamic Therapy.

PubMed

Wang, Jin; Liu, Qian; Zhang, Yuting; Shi, Huan; Liu, Hui; Guo, Wenjun; Ma, Yanhong; Huang, Weiqiang; Hong, Zhangyong

2017-06-01

Photodynamic therapy (PDT) is a highly localized and minimally invasive cancer treatment modality with many important advantages, but the lack of ideal photosensitizers (PSs) greatly restricts its clinical utility. To develop new PSs with highly efficient singlet oxygen production and high tumor-localizing ability to reduce damage to healthy adjacent tissues, we conjugated folic acid (FA) with pyropheophorbide a (Pyro), a potent PS with a very high singlet oxygen quantum yield and a high extinction coefficient. In the present work, we describe the synthesis and PDT evaluation of this FA-Pyro conjugate both in vitro and in vivo. This conjugation increased the accumulation of Pyro inside the tumors and improved the efficiency of PDT, resulting in eradication of subcutaneous xenograft KB (human mouth epidermal carcinoma) tumors after only 1 or 2 applications of external near infrared light irradiation. This outstanding PDT outcome in a tumor-bearing mouse model and the simple synthesis of the conjugate should have very good practical potential for clinical application. Copyright © 2017 American Pharmacists Association®. Published by Elsevier Inc. All rights reserved.

Influence of temperature and relative humidity conditions on the pan coating of hydroxypropyl cellulose molded capsules.

PubMed

Macchi, Elena; Zema, Lucia; Pandey, Preetanshu; Gazzaniga, Andrea; Felton, Linda A

2016-03-01

In a previous study, hydroxypropyl cellulose (HPC)-based capsular shells prepared by injection molding and intended for pulsatile release were successfully coated with 10mg/cm(2) Eudragit® L film. The suitability of HPC capsules for the development of a colon delivery platform based on a time dependent approach was demonstrated. In the present work, data logging devices (PyroButton®) were used to monitor the microenvironmental conditions, i.e. temperature (T) and relative humidity (RH), during coating processes performed under different spray rates (1.2, 2.5 and 5.5g/min). As HPC-based capsules present special features, a preliminary study was conducted on commercially available gelatin capsules for comparison purposes. By means of PyroButton data-loggers it was possible to acquire information about the impact of the effective T and RH conditions experienced by HPC substrates during the process on the technological properties and release performance of the coated systems. The use of increasing spray rates seemed to promote a tendency of the HPC shells to slightly swell at the beginning of the spraying process; moreover, capsules coated under spray rates of 1.2 and 2.5g/min showed the desired release performance, i.e. ability to withstand the acidic media followed by the pulsatile release expected for uncoated capsules. Preliminary stability studies seemed to show that coating conditions might also influence the release performance of the system upon storage. Copyright © 2015 Elsevier B.V. All rights reserved.

An integrated lean-methods approach to hospital facilities redesign.

PubMed

Nicholas, John

2012-01-01

Lean production methods for eliminating waste and improving processes in manufacturing are now being applied in healthcare. As the author shows, the methods are appropriate for redesigning hospital facilities. When used in an integrated manner and employing teams of mostly clinicians, the methods produce facility designs that are custom-fit to patient needs and caregiver work processes, and reduce operational costs. The author reviews lean methods and an approach for integrating them in the redesign of hospital facilities. A case example of the redesign of an emergency department shows the feasibility and benefits of the approach.

Chlorhexidine digluconate induces mitotic recombination in diploid cells of Aspergillus nidulans.

PubMed

Souza-Júnior, S A; Castro-Prado, M A A

2005-05-01

Chlorhexidine digluconate (1,1'-hexamethylene-bis[(5-p-clorophenyl)-biguanide]) is a bisbiguanidine antiseptic, used to decrease plaque formation and to control periodontal diseases. The determination of the frequency of mitotic crossing-over constitutes a very important method for detecting carcinogenic agents. The recombinogenic potential of chlorhexidine digluconate was evaluated on Aspergillus nidulans by the production of cells homozygous for the following nutritional markers: riboA1, pabaA124, biA1, methA17 and pyroA4. A. nidulans was exposed to three concentrations of chlorhexidine digluconate (1, 5, and 10 microM). Inhibition of colony development, conidiophore morphological alteration (cytotoxic effect), and the recombinogenic effect, indicated by homozygotization index (HI) values higher than 2.0, were observed for all concentrations of chlorhexidine digluconate. A homozygous pyro+//pyro+ diploid strain and a diploid homozygous for the recessive w gene were isolated from UT448//A757 diploid treated with chlorhexidine digluconate, emphasazing its recombinogenic potential. Although, beneficial effects of chlorhexidine, as an antiseptic agent, are reported in the literature, our results revealed that chlorhexidine digluconate, at less levels lowered those used clinically, caused toxic and recombinogenic effects on diploid A. nidulans strain.

Wildfire in the Critical Zone: Pyro-Geomorphic Feedbacks in Upland Forests

NASA Astrophysics Data System (ADS)

Sheridan, G. J.; Inbar, A.; Metzen, D.; Van der Sant, R.; Lane, P. N. J.; Nyman, P.

2017-12-01

Wildfire often triggers a dramatic geomorphic response, with erosion rates several orders of magnitude greater than background rates. The fact that wildfire is linked to increased soil erosion is well established, but could it also work the other way around? Is it possible that, over time, soil erosion could lead to an increase in wildfire? The proposed mechanism for this is a potential positive feedback between post-fire soil erosion, soil depth, and forest flammability. More fire-related erosion may, over time, lead to less soil water holding capacity, more open vegetation with drier fuels, more fire, and in turn more fire related erosion. These pyro-geomorphic feedbacks may help explain the co-evolved soil-vegetation-fire systems that are observed in the landscape. More broadly, the concept of "wildfire in the critical zone", with a greater emphasis on the interactions between fire, vegetation, hydrology, and geomorphology, may help us understand and predict the trajectory of change as the vegetation-soil-fire system responds and adjusts to the new climate forcing. This presentation will combine an extensive soil, vegetation, and post fire erosion experimental dataset, with conceptual and numerical modelling, to evaluate the significance of the potential pyro-geomorphic feedbacks described above.

Genesis failure investigation report : JPL Failure Review Board, Avionics Sub-Team

NASA Technical Reports Server (NTRS)

Klein, John; Manning, Rob; Barry, Ed; Donaldson, Jim; Rivellini, Tom; Battel, Steven; Savino, Joe; Lee, Wayne; Dalton, Jerry; Underwood, Mark;

INTEGRATION OF FACILITY MODELING CAPABILITIES FOR NUCLEAR NONPROLIFERATION ANALYSIS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gorensek, M.; Hamm, L.; Garcia, H.

2011-07-18

Developing automated methods for data collection and analysis that can facilitate nuclear nonproliferation assessment is an important research area with significant consequences for the effective global deployment of nuclear energy. Facility modeling that can integrate and interpret observations collected from monitored facilities in order to ascertain their functional details will be a critical element of these methods. Although improvements are continually sought, existing facility modeling tools can characterize all aspects of reactor operations and the majority of nuclear fuel cycle processing steps, and include algorithms for data processing and interpretation. Assessing nonproliferation status is challenging because observations can come frommore » many sources, including local and remote sensors that monitor facility operations, as well as open sources that provide specific business information about the monitored facilities, and can be of many different types. Although many current facility models are capable of analyzing large amounts of information, they have not been integrated in an analyst-friendly manner. This paper addresses some of these facility modeling capabilities and illustrates how they could be integrated and utilized for nonproliferation analysis. The inverse problem of inferring facility conditions based on collected observations is described, along with a proposed architecture and computer framework for utilizing facility modeling tools. After considering a representative sampling of key facility modeling capabilities, the proposed integration framework is illustrated with several examples.« less

MARS PATHFINDER PYRO SYSTEMS SWITCHING ACTIVITY

NASA Technical Reports Server (NTRS)

1996-01-01

The Mars Pathfinder lander is subjected to a electrical and functional tests of its pyrotechic petal deployer system by Jet Propulsion Laboratory (JPL) engineers and technicians in KSC's Spacecraft Assembly and Encapsulation Facility (SAEF-2). In the background is the Pathfinder cruise stage, which the lander will be mated to once its functional tests are complete. The lander will remain attached to this stage during its six-to-seven-month journey to Mars. When the lander touches down on the surface of Mars next year, the pyrotechnic system will deploy its three petals open like a flower and allow the Sojourner autonomous rover to explore the Martian surface. The Mars Pathfinder is scheduled for launch aboard a Delta II expendable launch vehicle on Dec. 2, the beginning of a 24-day launch period. JPL is managing the Mars Pathfinder project for NASA.

Electrochemical/Pyrometallurgical Waste Stream Processing and Waste Form Fabrication

DOE Office of Scientific and Technical Information (OSTI.GOV)

Steven Frank; Hwan Seo Park; Yung Zun Cho

This report summarizes treatment and waste form options being evaluated for waste streams resulting from the electrochemical/pyrometallurgical (pyro ) processing of used oxide nuclear fuel. The technologies that are described are South Korean (Republic of Korea – ROK) and United States of America (US) ‘centric’ in the approach to treating pyroprocessing wastes and are based on the decade long collaborations between US and ROK researchers. Some of the general and advanced technologies described in this report will be demonstrated during the Integrated Recycle Test (IRT) to be conducted as a part of the Joint Fuel Cycle Study (JFCS) collaboration betweenmore » US Department of Energy (DOE) and ROK national laboratories. The JFCS means to specifically address and evaluated the technological, economic, and safe guard issues associated with the treatment of used nuclear fuel by pyroprocessing. The IRT will involve the processing of commercial, used oxide fuel to recover uranium and transuranics. The recovered transuranics will then be fabricated into metallic fuel and irradiated to transmutate, or burn the transuranic elements to shorter lived radionuclides. In addition, the various process streams will be evaluated and tested for fission product removal, electrolytic salt recycle, minimization of actinide loss to waste streams and waste form fabrication and characterization. This report specifically addresses the production and testing of those waste forms to demonstrate their compatibility with treatment options and suitability for disposal.« less

Expert diagnostics system as a part of analysis software for power mission operations

NASA Technical Reports Server (NTRS)

Harris, Jennifer A.; Bahrami, Khosrow A.

1993-01-01

The operation of interplanetary spacecraft at JPL has become an increasingly complex activity. This complexity is due to advanced spacecraft designs and ambitious mission objectives which lead to operations requirements that are more demanding than those of any previous mission. For this reason, several productivity enhancement measures are underway at JPL within mission operations, particularly in the spacecraft analysis area. These measures aimed at spacecraft analysis include: the development of a multi-mission, multi-subsystem operations environment; the introduction of automated tools into this environment; and the development of an expert diagnostics system. This paper discusses an effort to integrate the above mentioned productivity enhancement measures. A prototype was developed that integrates an expert diagnostics system into a multi-mission, multi-subsystem operations environment using the Galileo Power / Pyro Subsystem as a testbed. This prototype will be discussed in addition to background information associated with it.

Process analytical technology (PAT) approach to the formulation of thermosensitive protein-loaded pellets: Multi-point monitoring of temperature in a high-shear pelletization.

PubMed

Kristó, Katalin; Kovács, Orsolya; Kelemen, András; Lajkó, Ferenc; Klivényi, Gábor; Jancsik, Béla; Pintye-Hódi, Klára; Regdon, Géza

2016-12-01

In the literature there are some publications about the effect of impeller and chopper speeds on product parameters. However, there is no information about the effect of temperature. Therefore our main aim was the investigation of elevated temperature and temperature distribution during pelletization in a high shear granulator according to process analytical technology. During our experimental work, pellets containing pepsin were formulated with a high-shear granulator. A specially designed chamber (Opulus Ltd.) was used for pelletization. This chamber contained four PyroButton-TH® sensors built in the wall and three PyroDiff® sensors 1, 2 and 3cm from the wall. The sensors were located in three different heights. The impeller and chopper speeds were set on the basis of 3 2 factorial design. The temperature was measured continuously in 7 different points during pelletization and the results were compared with the temperature values measured by the thermal sensor of the high-shear granulator. The optimization parameters were enzyme activity, average size, breaking hardness, surface free energy and aspect ratio. One of the novelties was the application of the specially designed chamber (Opulus Ltd.) for monitoring the temperature continuously in 7 different points during high-shear granulation. The other novelty of this study was the evaluation of the effect of temperature on the properties of pellets containing protein during high-shear pelletization. Copyright © 2016 Elsevier B.V. All rights reserved.

Pyro-synthesis of a high rate nano-Li3V2(PO4)3/C cathode with mixed morphology for advanced Li-ion batteries.

PubMed

Kang, Jungwon; Mathew, Vinod; Gim, Jihyeon; Kim, Sungjin; Song, Jinju; Im, Won Bin; Han, Junhee; Lee, Jeong Yong; Kim, Jaekook

2014-02-10

A monoclinic Li3V2(PO4)3/C (LVP/C) cathode for lithium battery applications was synthesized by a polyol-assisted pyro-synthesis. The polyol in the present synthesis acts not only as a solvent, reducing agent and a carbon source but also as a low-cost fuel that facilitates a combustion process combined with the release of ultrahigh exothermic energy useful for nucleation process. Subsequent annealing of the amorphous particles at 800°C for 5 h is sufficient to produce highly crystalline LVP/C nanoparticles. A combined analysis of X-ray diffraction (XRD) and neutron powder diffraction (NPD) patterns was used to determine the unit cell parameters of the prepared LVP/C. Electron microscopic studies revealed rod-type particles of length ranging from nanometer to micrometers dispersed among spherical particles with average particle-sizes in the range of 20-30 nm. When tested for Li-insertion properties in the potential windows of 3-4.3 and 3-4.8 V, the LVP/C cathode demonstrated initial discharge capacities of 131 and 196 mAh/g (~100% theoretical capacities) at 0.15 and 0.1 C current densities respectively with impressive capacity retentions for 50 cycles. Interestingly, the LVP/C cathode delivered average specific capacities of 125 and 90 mAh/g at current densities of 9.6 C and 15 C respectively within the lower potential window.

The influences of wildfires and stratospheric-tropospheric exchange on ozone during seacions mission over St. Louis

NASA Astrophysics Data System (ADS)

Wilkins, Joseph L.

The influence of wildfire biomass burning and stratospheric air mass transport on tropospheric ozone (O3) concentrations in St. Louis during the SEAC4RS and SEACIONS-2013 measurement campaigns has been investigated. The Lagrangian particle dispersion model FLEXPART-WRF analysis reveals that 55% of ozonesonde profiles during SEACIONS were effected by biomass burning. Comparing ozonesonde profiles with numerical simulations show that as biomass burning plumes age there is O3 production aloft. A new plume injection height technique was developed based on the Naval Research Laboratory's (NRL) detection algorithm for pyro-convection. The NRL method identified 29 pyro-cumulonimbus events that occurred during the summer of 2013, of which 13 (44%) impacted the SEACIONS study area, and 4 (14%) impacted the St. Louis area. In this study, we investigate wildfire plume injection heights using model simulations and the FLAMBE emissions inventory using 2 different algorithms. In the first case, wildfire emissions are injected at the surface and allowed to mix within the boundary layer simulated by the meteorological model. In the second case, the injection height of wildfire emissions is determined by a guided deep-convective pyroCb run using the NRL detection algorithm. Results show that simulations using surface emissions were able to represent the transport of carbon monoxide plumes from wildfires when the plumes remained below 5 km or occurred during large convective systems, but that the surface effects were over predicted. The pyroCb cases simulated the long-range transport of elevated plumes above 5 km 68% of the time. In addition analysis of potential vorticity suggests that stratospheric intrusions or tropopause folds affected 13 days (48%) when there were sonde launches and 27 days (44%) during the entire study period. The largest impact occurred on September 12, 2013 when ozone-rich air impacted the nocturnal boundary layer. By analyzing ozonesonde profiles with meteorological transport models, we were able to identify biomass burning and stratospheric intrusions in St. Louis.

Walk-through survey report: Control technology for integrated circuit fabrication, Xerox Corporation, El Segundo, California

NASA Astrophysics Data System (ADS)

Mihlan, G. J.; Ungers, L. J.; Smith, R. K.; Mitchell, R. I.; Jones, J. H.

1983-05-01

A preliminary control technology assessment survey was conducted at the facility which manufactures N-channel metal oxide semiconductor (NMOS) integrated circuits. The facility has industrial hygiene review procedures for evaluating all new and existing process equipment. Employees are trained in safety, use of personal protective equipment, and emergency response. Workers potentially exposed to arsenic are monitored for urinary arsenic levels. The facility should be considered a candidate for detailed study based on the diversity of process operations encountered and the use of state-of-the-art technology and process equipment.

Demonstration of a real-time interferometer as a bunch-length monitor in a high-current electron beam accelerator.

PubMed

Thangaraj, J; Andonian, G; Thurman-Keup, R; Ruan, J; Johnson, A S; Lumpkin, A; Santucci, J; Maxwell, T; Murokh, A; Ruelas, M; Ovodenko, A

2012-04-01

A real-time interferometer (RTI) has been developed to monitor the bunch length of an electron beam in an accelerator. The RTI employs spatial autocorrelation, reflective optics, and a fast response pyro-detector array to obtain a real-time autocorrelation trace of the coherent radiation from an electron beam thus providing the possibility of online bunch-length diagnostics. A complete RTI system has been commissioned at the A0 photoinjector facility to measure sub-mm bunches at 13 MeV. Bunch length variation (FWHM) between 0.8 ps (~0.24 mm) and 1.5 ps (~0.45 mm) has been measured and compared with a Martin-Puplett interferometer and a streak camera. The comparisons show that RTI is a viable, complementary bunch length diagnostic for sub-mm electron bunches. © 2012 American Institute of Physics

Verification study of an emerging fire suppression system

DOE PAGES

Cournoyer, Michael E.; Waked, R. Ryan; Granzow, Howard N.; ...

2016-01-01

Self-contained fire extinguishers are a robust, reliable and minimally invasive means of fire suppression for gloveboxes. Moreover, plutonium gloveboxes present harsh environmental conditions for polymer materials; these include radiation damage and chemical exposure, both of which tend to degrade the lifetime of engineered polymer components. Several studies have been conducted to determine the robustness of selfcontained fire extinguishers in plutonium gloveboxes in a nuclear facility, verification tests must be performed. These tests include activation and mass loss calorimeter tests. In addition, compatibility issues with chemical components of the self-contained fire extinguishers need to be addressed. Our study presents activation andmore » mass loss calorimeter test results. After extensive studies, no critical areas of concern have been identified for the plutonium glovebox application of Fire Foe™, except for glovebox operations that use large quantities of bulk plutonium or uranium metal such as metal casting and pyro-chemistry operations.« less

Verification study of an emerging fire suppression system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cournoyer, Michael E.; Waked, R. Ryan; Granzow, Howard N.

Self-contained fire extinguishers are a robust, reliable and minimally invasive means of fire suppression for gloveboxes. Moreover, plutonium gloveboxes present harsh environmental conditions for polymer materials; these include radiation damage and chemical exposure, both of which tend to degrade the lifetime of engineered polymer components. Several studies have been conducted to determine the robustness of selfcontained fire extinguishers in plutonium gloveboxes in a nuclear facility, verification tests must be performed. These tests include activation and mass loss calorimeter tests. In addition, compatibility issues with chemical components of the self-contained fire extinguishers need to be addressed. Our study presents activation andmore » mass loss calorimeter test results. After extensive studies, no critical areas of concern have been identified for the plutonium glovebox application of Fire Foe™, except for glovebox operations that use large quantities of bulk plutonium or uranium metal such as metal casting and pyro-chemistry operations.« less

Demonstration of a real-time interferometer as a bunch-lenght monitor in a high-current electron beam accelerator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thangaraj, J.; Thurman-Keup, R.; Ruan, J.

2012-03-01

A real-time interferometer (RTI) has been developed to monitor the bunch length of an electron beam in an accelerator. The RTI employs spatial autocorrelation, reflective optics, and a fast response pyro-detector array to obtain a real-time autocorrelation trace of the coherent radiation from an electron beam thus providing the possibility of online bunch-length diagnostics. A complete RTI system has been commissioned at the A0 photoinjector facility to measure sub-mm bunches at 13 MeV. Bunch length variation (FWHM) between 0.8 ps (-0.24 mm) and 1.5 ps (-0.45 mm) has been measured and compared with a Martin-Puplett interferometer and a streak camera.more » The comparisons show that RTI is a viable, complementary bunch length diagnostic for sub-mm electron bunches.« less

Demonstration of a real-time interferometer as a bunch-length monitor in a high-current electron beam accelerator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thangaraj, J.; Thurman-Keup, R.; Ruan, J.

2012-04-15

A real-time interferometer (RTI) has been developed to monitor the bunch length of an electron beam in an accelerator. The RTI employs spatial autocorrelation, reflective optics, and a fast response pyro-detector array to obtain a real-time autocorrelation trace of the coherent radiation from an electron beam thus providing the possibility of online bunch-length diagnostics. A complete RTI system has been commissioned at the A0 photoinjector facility to measure sub-mm bunches at 13 MeV. Bunch length variation (FWHM) between 0.8 ps ({approx}0.24 mm) and 1.5 ps ({approx}0.45 mm) has been measured and compared with a Martin-Puplett interferometer and a streak camera.more » The comparisons show that RTI is a viable, complementary bunch length diagnostic for sub-mm electron bunches.« less

Common Utilities in the Energy Systems Integration Facility | Energy

Science.gov Websites

Systems Integration Facility. Common utilities include: Power: Three-phase 480/277 VAC, 208/120 VAC, 240 split-phase VAC, and 120 single-phase VAC Water: Process heating and cooling and research cooling

Energy Systems Integration News | Energy Systems Integration Facility |

Science.gov Websites

, consider the tangible benefits it can bring to utilities and the developer community, and discuss the Energy Systems Integration Facility on July 13 and 14, 2016, to discuss current and future R&D to researching this topic from a technology, business process, and policy perspective. This workshop is an

Contamination control and cleanliness level integrity for the Space Shuttle Orbiter PLB, payloads and facilities at KSC

NASA Technical Reports Server (NTRS)

Bartelson, D.

1984-01-01

The PLB, its cargo, and payload canister must satisfy the cleanliness requirements of visual clean (VC) level 1, 2, 3, or special as stated in NASA document SN-C-0005A. The specific level of cleanliness is chosen by the payload bay customer for their mission. During orbiter turnaround processing at KSC, the payload bay is exposed to the environments of the Orbiter Processing Facility (OPF) and the Payload Changeout Room (PCR). In supportive response to the orbiter payload bay/facility interface, it is necessary that the facility environment be controlled and monitored to protect the cleanliness/environmental integrity of the payload bay and its cargo. Techniques used to meet environmental requirements during orbiter processing are introduced.

Comprehensive integrated planning: A process for the Oak Ridge Reservation, Oak Ridge, Tennessee

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1998-05-01

The Oak Ridge Comprehensive Integrated Plan is intended to assist the US Department of Energy (DOE) and contractor personnel in implementing a comprehensive integrated planning process consistent with DOE Order 430.1, Life Cycle Asset Management and Oak Ridge Operations Order 430. DOE contractors are charged with developing and producing the Comprehensive Integrated Plan, which serves as a summary document, providing information from other planning efforts regarding vision statements, missions, contextual conditions, resources and facilities, decision processes, and stakeholder involvement. The Comprehensive Integrated Plan is a planning reference that identifies primary issues regarding major changes in land and facility use andmore » serves all programs and functions on-site as well as the Oak Ridge Operations Office and DOE Headquarters. The Oak Ridge Reservation is a valuable national resource and is managed on the basis of the principles of ecosystem management and sustainable development and how mission, economic, ecological, social, and cultural factors are used to guide land- and facility-use decisions. The long-term goals of the comprehensive integrated planning process, in priority order, are to support DOE critical missions and to stimulate the economy while maintaining a quality environment.« less

Feasibility study of a gamma camera for monitoring nuclear materials in the PRIDE facility

NASA Astrophysics Data System (ADS)

Jo, Woo Jin; Kim, Hyun-Il; An, Su Jung; Lee, Chae Young; Song, Han-Kyeol; Chung, Yong Hyun; Shin, Hee-Sung; Ahn, Seong-Kyu; Park, Se-Hwan

2014-05-01

The Korea Atomic Energy Research Institute (KAERI) has been developing pyroprocessing technology, in which actinides are recovered together with plutonium. There is no pure plutonium stream in the process, so it has an advantage of proliferation resistance. Tracking and monitoring of nuclear materials through the pyroprocess can significantly improve the transparency of the operation and safeguards. An inactive engineering-scale integrated pyroprocess facility, which is the PyRoprocess Integrated inactive DEmonstration (PRIDE) facility, was constructed to demonstrate engineering-scale processes and the integration of each unit process. the PRIDE facility may be a good test bed to investigate the feasibility of a nuclear material monitoring system. In this study, we designed a gamma camera system for nuclear material monitoring in the PRIDE facility by using a Monte Carlo simulation, and we validated the feasibility of this system. Two scenarios, according to locations of the gamma camera, were simulated using GATE (GEANT4 Application for Tomographic Emission) version 6. A prototype gamma camera with a diverging-slat collimator was developed, and the simulated and experimented results agreed well with each other. These results indicate that a gamma camera to monitor the nuclear material in the PRIDE facility can be developed.

Integrated water management system - Description and test results. [for Space Station waste water processing

NASA Technical Reports Server (NTRS)

Elden, N. C.; Winkler, H. E.; Price, D. F.; Reysa, R. P.

1983-01-01

Water recovery subsystems are being tested at the NASA Lyndon B. Johnson Space Center for Space Station use to process waste water generated from urine and wash water collection facilities. These subsystems are being integrated into a water management system that will incorporate wash water and urine processing through the use of hyperfiltration and vapor compression distillation subsystems. Other hardware in the water management system includes a whole body shower, a clothes washing facility, a urine collection and pretreatment unit, a recovered water post-treatment system, and a water quality monitor. This paper describes the integrated test configuration, pertinent performance data, and feasibility and design compatibility conclusions of the integrated water management system.

Launch Services Safety Overview

NASA Technical Reports Server (NTRS)

Loftin, Charles E.

2008-01-01

NASA/KSC Launch Services Division Safety (SA-D) services include: (1) Assessing the safety of the launch vehicle (2) Assessing the safety of NASA ELV spacecraft (S/C) / launch vehicle (LV) interfaces (3) Assessing the safety of spacecraft processing to ensure resource protection of: - KSC facilities - KSC VAFB facilities - KSC controlled property - Other NASA assets (4) NASA personnel safety (5) Interfacing with payload organizations to review spacecraft for adequate safety implementation and compliance for integrated activities (6) Assisting in the integration of safety activities between the payload, launch vehicle, and processing facilities

Fabrication of optical microlenses by a new inkjet printing technique based on pyro-electrohydrodynamic (PEHD) effect

NASA Astrophysics Data System (ADS)

Coppola, S.; Vespini, V.; Grimaldi, I. A.; Loffredo, F.; Villani, F.; Miccio, L.; Grilli, S.; Ferraro, P.

2012-06-01

Here the pyroelectric functionality of a Lithium Niobate (LN) substrate is used for non-contact manipulation of liquids. In this work we introduced the use of a pyro-electrohydrodynamc (PEHD) dispenser for the manipulation of high viscous polymer materials leading to the fabrication of arrays of microlenses. The set-up used for the experiment is described and the fabricated microlenses are analyzed by means of the Digital Holography (DH) set-up in transmission mode and through profilometric analysis. PMMA based ink was employed for the realization of optical quality microsctructures whose geometrical properties and, hence, the focal lengths were controlled by modifying the printing configuration of the PEHD method. The profilometric results are in agreement with those calculated using the digital holography technique.

Chemical synthesis of 5'-pyrophosphate and triphosphate derivatives of 3'-5' ApA, ApG, GpA and GpG. CD study of the effect of 5'-phosphate groups on the conformation of 3'-5' GpG.

PubMed Central

Tomasz, J; Simoncsits, A; Kajtár, M; Krug, R M; Shatkin, A J

1978-01-01

A simple, two-step method is described for the synthesis of the 5'-pyro- and triphosphate derivatives of 3'-5' ApA, ApG, GpA and GpG. The readily accessible 2'(3')-5' ApA, ApG, GpA and GpG were converted in one step to the corresponding 5'-phosphoramidate derivatives which were then transformed to the 5'-pyro- and triphosphates. CD spectra of 3'-5' pn GpG (n = 0,1,2 or 3) derivatives, measured at pH 1, indicated stabilization of the (syn) G+p (anti)G conformation by the 5'-phosphate groups. PMID:211490

Investigation on cone jetting regimes of liquid droplets subjected to pyroelectric fields induced by laser blasts

NASA Astrophysics Data System (ADS)

Gennari, Oriella; Battista, Luigi; Silva, Benjamin; Grilli, Simonetta; Miccio, Lisa; Vespini, Veronica; Coppola, Sara; Orlando, Pierangelo; Aprin, Laurent; Slangen, Pierre; Ferraro, Pietro

2015-02-01

Electrical conductivity and viscosity play a major role in the tip jetting behaviour of liquids subjected to electrohydrodynamic (EHD) forces, thus influencing significantly the printing performance. Recently, we developed a nozzle- and electrode-free pyro-EHD system as a versatile alternative to conventional EHD configurations and we demonstrated different applications, including inkjet printing and three-dimensional lithography. However, only dielectric fluids have been used in all of those applications. Here, we present an experimental characterization of the pyro-EHD jetting regimes, induced by laser blasts, of sessile drops in case of dielectric and conductive liquids in order to extend the applicability of the system to a wider variety of fields including biochemistry and biotechnology where conductive aqueous solutions are typically used.

GEOTAIL Spacecraft historical data report

NASA Technical Reports Server (NTRS)

Boersig, George R.; Kruse, Lawrence F.

1993-01-01

The purpose of this GEOTAIL Historical Report is to document ground processing operations information gathered on the GEOTAIL mission during processing activities at the Cape Canaveral Air Force Station (CCAFS). It is hoped that this report may aid management analysis, improve integration processing and forecasting of processing trends, and reduce real-time schedule changes. The GEOTAIL payload is the third Delta 2 Expendable Launch Vehicle (ELV) mission to document historical data. Comparisons of planned versus as-run schedule information are displayed. Information will generally fall into the following categories: (1) payload stay times (payload processing facility/hazardous processing facility/launch complex-17A); (2) payload processing times (planned, actual); (3) schedule delays; (4) integrated test times (experiments/launch vehicle); (5) unique customer support requirements; (6) modifications performed at facilities; (7) other appropriate information (Appendices A & B); and (8) lessons learned (reference Appendix C).

Pyro-electrification of polymer membranes for cell patterning

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rega, R.; Gennari, O.; Mecozzia, L.

2016-05-18

In the recent years, much attention has been devoted to the possibility of charging polymer-based materials, due to their potential in developing large-scale and inexpensive flexible thin-film technology. The availability of localized electrostatic fields is in of great interest for a huge amount of applications such as distribution of biomolecules and cells from the liquid phase. Here we report a voltage-free pyro-electrification (PE) process able to induce permanent dipoles into polymer layers; the lithium niobate (LN) crystal is the key component that plays the multi-purpose role of sustaining, heating and poling the polymer layer that is then peeled-off easily inmore » order to have a free-standing charged membrane. The results show the fascinating application for the living cell patterning. It well known that cell behaviour is affected by chemical and topographical cues of substrate. In fact, polymers, such as polystyrene (PS) and poly(methyl methacrylate) (PMMA), are naturally cytophobic and require specific functionalization treatments in order to promote cell adhesion. Through our proposal technique, it’s possible to obtain spontaneous organization and a driven growth of SH-SY5Y cells that is solely dictated by the nature of the charge polymer surface, opening, in this way, the innovative chance to manipulate and transfer biological samples on a free-standing polymer layer [1].« less

Guidelines of the Design of Electropyrotechnic Firing Circuit for Unmanned Flight and Ground Test Projects

NASA Technical Reports Server (NTRS)

Gonzalez, Guillermo A.; Lucy, Melvin H.; Massie, Jeffrey J.

2013-01-01

The NASA Langley Research Center, Engineering Directorate, Electronic System Branch, is responsible for providing pyrotechnic support capabilities to Langley Research Center unmanned flight and ground test projects. These capabilities include device selection, procurement, testing, problem solving, firing system design, fabrication and testing; ground support equipment design, fabrication and testing; checkout procedures and procedure?s training to pyro technicians. This technical memorandum will serve as a guideline for the design, fabrication and testing of electropyrotechnic firing systems. The guidelines will discuss the entire process beginning with requirements definition and ending with development and execution.

SLURRY SOLVENT EXTRACTION PROCESS FOR THE RECOVERY OF METALS FROM SOLID MATERIALS

DOEpatents

Grinstead, R.R.

1959-01-20

A solvent extraction process is described for recovering uranium from low grade uranium bearing minerals such as carnotit or shale. The finely communited ore is made up as an aqueous slurry containing the necessary amount of acid to solubilize the uranium and simultaneously or subsequently contacted with an organic solvent extractant such as the alkyl ortho-, or pyro phosphoric acids, alkyl phosphites or alkyl phosphonates in combination with a diluent such as kerosene or carbon tetrachlorids. The extractant phase is separated from the slurry and treated by any suitable process to recover the uranium therefrom. One method for recovering the uranium comprises treating the extract with aqueous HF containing a reducing agent such as ferrous sulfate, which reduces the uranium and causes it to be precipitated as uranium tetrafluoride.

The LEAN Payload Integration Process

NASA Technical Reports Server (NTRS)

Jordan, Lee P.; Young, Yancy; Rice, Amanda

2011-01-01

It is recognized that payload development and integration with the International Space Station (ISS) can be complex. This streamlined integration approach is a first step toward simplifying payload integration; making it easier to fly payloads on ISS, thereby increasing feasibility and interest for more research and commercial organizations to sponsor ISS payloads and take advantage of the ISS as a National Laboratory asset. The streamlined integration approach was addressed from the perspective of highly likely initial payload types to evolve from the National Lab Pathfinder program. Payloads to be accommodated by the Expedite the Processing of Experiments for Space Station (EXPRESS) Racks and Microgravity Sciences Glovebox (MSG) pressurized facilities have been addressed. It is hoped that the streamlined principles applied to these types of payloads will be analyzed and implemented in the future for other host facilities as well as unpressurized payloads to be accommodated by the EXPRESS Logistics Carrier (ELC). Further, a payload does not have to be classified as a National Lab payload in order to be processed according to the lean payload integration process; any payload that meets certain criteria can follow the lean payload integration process.

40 CFR 63.7782 - What parts of my plant does this subpart cover?

Code of Federal Regulations, 2014 CFR

2014-07-01

... oxygen process furnace (BOPF) shop at your integrated iron and steel manufacturing facility. (c) This... blast furnace casthouse; and the BOPF shop including each individual BOPF and shop ancillary operations... plant, blast furnace, or BOPF shop at your integrated iron and steel manufacturing facility is existing...

40 CFR 63.7782 - What parts of my plant does this subpart cover?

Code of Federal Regulations, 2013 CFR

2013-07-01

... oxygen process furnace (BOPF) shop at your integrated iron and steel manufacturing facility. (c) This... blast furnace casthouse; and the BOPF shop including each individual BOPF and shop ancillary operations... plant, blast furnace, or BOPF shop at your integrated iron and steel manufacturing facility is existing...

40 CFR 63.7782 - What parts of my plant does this subpart cover?

Code of Federal Regulations, 2012 CFR

2012-07-01

... oxygen process furnace (BOPF) shop at your integrated iron and steel manufacturing facility. (c) This... blast furnace casthouse; and the BOPF shop including each individual BOPF and shop ancillary operations... plant, blast furnace, or BOPF shop at your integrated iron and steel manufacturing facility is existing...

40 CFR 63.7782 - What parts of my plant does this subpart cover?

Code of Federal Regulations, 2011 CFR

2011-07-01

... oxygen process furnace (BOPF) shop at your integrated iron and steel manufacturing facility. (c) This... blast furnace casthouse; and the BOPF shop including each individual BOPF and shop ancillary operations... plant, blast furnace, or BOPF shop at your integrated iron and steel manufacturing facility is existing...

40 CFR 63.7782 - What parts of my plant does this subpart cover?

Code of Federal Regulations, 2010 CFR

2010-07-01

... oxygen process furnace (BOPF) shop at your integrated iron and steel manufacturing facility. (c) This... blast furnace casthouse; and the BOPF shop including each individual BOPF and shop ancillary operations... plant, blast furnace, or BOPF shop at your integrated iron and steel manufacturing facility is existing...

Pyro-phototronic nanogenerator based on flexible 2D ZnO/graphene heterojunction and its application in self-powered near infrared photodetector and active analog frequency modulation.

PubMed

Sahatiya, Parikshit; Shinde, Akash; Badhulika, Sushmee

2018-08-10

Even though 2D ZnO has been utilized for enhanced self-powered sensing by strain modulation due to its piezoelectric property, study on utilizing the pyroelectric property of ZnO remains unexplored. The piezoelectric property of 2D ZnO works on mechanical strain, which disrupts the structure of ZnO leading to the failure of the device. For a pyroelectric nanogenerator, the temperature difference can be triggered by an external light source, which does not disrupt the ZnO structure and also avoids the need for physical bending/pressing, as in the case of a piezoelectric nanogenerator. This work represents the first demonstration of the fabrication of a flexible 2D ZnO/Gr pyro-phototronic diode where the pyro-potential generated in the 2D ZnO due to the near infrared (NIR) illumination adds to or subtracts from the built-in electric field of the heterojunction and modulates the depletion region of the heterojunction thereby enabling bias-free operation. Furthermore, the variation in the depletion width of the heterojunction was utilized as a variable capacitor in the frequency modulator, wherein, with the increasing intensity, the frequency of oscillations increased from 9.8 to 10.42 MHz. The work presented provides an alternative approach for a self-powered NIR photodetector and the utilization of the same at circuit level, having potential applications in the fields of optothermal detection, electronic tuning circuits, etc.

Comprehensive mapping and characteristic regimes of aerosol effects on the formation and evolution of pyro-convective clouds

DOE PAGES

Chang, D.; Cheng, Y.; Reutter, P.; ...

2015-09-21

Here, a recent parcel model study (Reutter et al., 2009) showed three deterministic regimes of initial cloud droplet formation, characterized by different ratios of aerosol concentrations ( N CN) to updraft velocities. This analysis, however, did not reveal how these regimes evolve during the subsequent cloud development. To address this issue, we employed the Active Tracer High Resolution Atmospheric Model (ATHAM) with full microphysics and extended the model simulation from the cloud base to the entire column of a single pyro-convective mixed-phase cloud. A series of 2-D simulations (over 1000) were performed over a wide range of N CN andmore » dynamic conditions. The integrated concentration of hydrometeors over the full spatial and temporal scales was used to evaluate the aerosol and dynamic effects. The results show the following. (1) The three regimes for cloud condensation nuclei (CCN) activation in the parcel model (namely aerosol-limited, updraft-limited, and transitional regimes) still exist within our simulations, but net production of raindrops and frozen particles occurs mostly within the updraft-limited regime. (2) Generally, elevated aerosols enhance the formation of cloud droplets and frozen particles. The response of raindrops and precipitation to aerosols is more complex and can be either positive or negative as a function of aerosol concentrations. The most negative effect was found for values of N CN of ~ 1000 to 3000 cm –3. (3) The nonlinear properties of aerosol–cloud interactions challenge the conclusions drawn from limited case studies in terms of their representativeness, and ensemble studies over a wide range of aerosol concentrations and other influencing factors are strongly recommended for a more robust assessment of the aerosol effects.« less

Pointers, Lessons Learned, and Rules of Thumb for Successful Vibro-Acoustic Data Acquisition

NASA Technical Reports Server (NTRS)

Rossoni, Peter

1998-01-01

This presentation contains helpful pointers for successful vibroacoustic data acquisition in the following three areas: Instrumentation, Vibration Control and Pyro-shock data acquisition and analysis. A helpful bibliography is provided.

Thermochemical Users Facility | Bioenergy | NREL

Science.gov Websites

collaborate on research and development efforts or to use our equipment to test their materials and processes NREL's thermochemical process integration, scale-up, and piloting research. Schematic diagram of NRELs about NREL's thermochemical process integration, scale-up, and piloting research. Thermochemical

Toward the Factory of the Future.

ERIC Educational Resources Information Center

Hazony, Yehonathan

1983-01-01

Computer-integrated manufacturing (CIM) involves use of data processing technology as the vehicle for full integration of the total manufacturing process. A prototype research and educational facility for CIM developed with industrial sponsorship at Princeton University is described. (JN)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Williams, Edward J., Jr.; Henry, Karen Lynne

Sandia National Laboratories develops technologies to: (1) sustain, modernize, and protect our nuclear arsenal (2) Prevent the spread of weapons of mass destruction; (3) Provide new capabilities to our armed forces; (4) Protect our national infrastructure; (5) Ensure the stability of our nation's energy and water supplies; and (6) Defend our nation against terrorist threats. We identified the need for a single overarching Integrated Workplace Management System (IWMS) that would enable us to focus on customer missions and improve FMOC processes. Our team selected highly configurable commercial-off-the-shelf (COTS) software with out-of-the-box workflow processes that integrate strategic planning, project management, facilitymore » assessments, and space management, and can interface with existing systems, such as Oracle, PeopleSoft, Maximo, Bentley, and FileNet. We selected the Integrated Workplace Management System (IWMS) from Tririga, Inc. Facility Management System (FMS) Benefits are: (1) Create a single reliable source for facility data; (2) Improve transparency with oversight organizations; (3) Streamline FMOC business processes with a single, integrated facility-management tool; (4) Give customers simple tools and real-time information; (5) Reduce indirect costs; (6) Replace approximately 30 FMOC systems and 60 homegrown tools (such as Microsoft Access databases); and (7) Integrate with FIMS.« less

The Galileo PPS expert monitoring and diagnostic prototype

NASA Technical Reports Server (NTRS)

Bahrami, Khosrow

1989-01-01

The Galileo PPS Expert Monitoring Module (EMM) is a prototype system implemented on the SUN workstation that will demonstrate a knowledge-based approach to monitoring and diagnosis for the Galileo spacecraft Power/Pyro subsystems. The prototype will simulate an analysis module functioning within the SFOC Engineering Analysis Subsystem Environment (EASE). This document describes the implementation of a prototype EMM for the Galileo spacecraft Power Pyro Subsystem. Section 2 of this document provides an overview of the issues in monitoring and diagnosis and comparison between traditional and knowledge-based solutions to this problem. Section 3 describes various tradeoffs which must be considered when designing a knowledge-based approach to monitoring and diagnosis, and section 4 discusses how these issues were resolved in constructing the prototype. Section 5 presents conclusions and recommendations for constructing a full-scale demonstration of the EMM. A Glossary provides definitions of terms used in this text.

Pyro-Synthesis of Functional Nanocrystals

PubMed Central

Gim, Jihyeon; Mathew, Vinod; Lim, Jinsub; Song, Jinju; Baek, Sora; Kang, Jungwon; Ahn, Docheon; Song, Sun-Ju; Yoon, Hyeonseok; Kim, Jaekook

2012-01-01

Despite nanomaterials with unique properties playing a vital role in scientific and technological advancements of various fields including chemical and electrochemical applications, the scope for exploration of nano-scale applications is still wide open. The intimate correlation between material properties and synthesis in combination with the urgency to enhance the empirical understanding of nanomaterials demand the evolution of new strategies to promising materials. Herein we introduce a rapid pyro-synthesis that produces highly crystalline functional nanomaterials under reaction times of a few seconds in open-air conditions. The versatile technique may facilitate the development of a variety of nanomaterials and, in particular, carbon-coated metal phosphates with appreciable physico-chemical properties benefiting energy storage applications. The present strategy may present opportunities to develop “design rules” not only to produce nanomaterials for various applications but also to realize cost-effective and simple nanomaterial production beyond lab-scale limitations. PMID:23230511

Formation of specific amino acid sequences during carbodiimide-mediated condensation of amino acids in aqueous solution, and computer-simulated sequence generation

NASA Astrophysics Data System (ADS)

Hartmann, Jürgen; Nawroth, Thomas; Dose, Klaus

1984-12-01

Carbodiimide-mediated peptide synthesis in aqueous solution has been studied with respect to self-ordering of amino acids. The copolymerisation of amino acids in the presence of glutamic acid or pyroglutamic acid leads to short pyroglutamyl peptides. Without pyroglutamic acid the formation of higher polymers is favoured. The interactions of the amino acids and the peptides, however, are very complex. Therefore, the experimental results are rather difficult to explain. Some of the experimental results, however, can be explained with the aid of computer simulation programs. Regarding only the tripeptide fraction the copolymerisation of pyroGlu, Ala and Leu, as well as the simulated copolymerisation lead to pyroGlu-Ala-Leu as the main reaction product. The amino acid composition of the insoluble peptides formed during the copolymerisation of Ser, Gly, Ala, Val, Phe, Leu and Ile corresponds in part to the computer-simulated copolymerisation data.

Pyro-synthesis of functional nanocrystals.

PubMed

Gim, Jihyeon; Mathew, Vinod; Lim, Jinsub; Song, Jinju; Baek, Sora; Kang, Jungwon; Ahn, Docheon; Song, Sun-Ju; Yoon, Hyeonseok; Kim, Jaekook

2012-01-01

Despite nanomaterials with unique properties playing a vital role in scientific and technological advancements of various fields including chemical and electrochemical applications, the scope for exploration of nano-scale applications is still wide open. The intimate correlation between material properties and synthesis in combination with the urgency to enhance the empirical understanding of nanomaterials demand the evolution of new strategies to promising materials. Herein we introduce a rapid pyro-synthesis that produces highly crystalline functional nanomaterials under reaction times of a few seconds in open-air conditions. The versatile technique may facilitate the development of a variety of nanomaterials and, in particular, carbon-coated metal phosphates with appreciable physico-chemical properties benefiting energy storage applications. The present strategy may present opportunities to develop "design rules" not only to produce nanomaterials for various applications but also to realize cost-effective and simple nanomaterial production beyond lab-scale limitations.

Pyro-paraelectric and flexocaloric effects in barium strontium titanate: A first principles approach

DOE Office of Scientific and Technical Information (OSTI.GOV)

Patel, Satyanarayan; Vaish, Rahul, E-mail: rahul@iitmandi.ac.in; Chauhan, Aditya

2016-04-18

Inhomogeneous strain allows the manifestation of an unexplored component of stress-driven caloric effect (flexocaloric effect) and enhanced pyroelectric performance, obtainable significantly beyond the Curie point. A peak temperature change of 1.5 K (at 289 K) was predicted from first-principles-based simulations for Ba{sub 0.5}Sr{sub 0.5}TiO{sub 3} under the application of a strain gradient of 1.5 μm{sup −1}. Additionally, enhanced pyro-paraelectric coefficient (pyroelectric coefficient in paraelectric phase) and flexocaloric cooling 11 × 10{sup −4} C m{sup −2 }K{sup −1} and 1.02 K, respectively, could be obtained (at 330 K and 1.5 μm{sup −1}). A comparative analysis with prevailing literature indicates huge untapped potential and warrants further research.

Environmental Test Program for the Mars Exploration Rover Project

NASA Technical Reports Server (NTRS)

Fisher, Terry C.; VanVelzer, Paul L.

2004-01-01

On June 10 and July 7, 2003 the National Aeronautics and Space Administration (NASA) launched two spacecraft from Cape Canaveral, Florida for a six (6) months flight to the Red Planet, Mars. The two Mars Exploration Rover spacecraft landed safely on the planet in January 2004. Prior to the successful launch, both of the spacecraft were involved in a comprehensive test campaign that included development, qualification, and protoflight test programs. Testing was performed to simulate the environments associated with launch, inter-planetary cruise, landing on the planet and Mars surface operations. Unique test requirements included operating the spacecraft while the chamber pressure was controlled to simulate the decent to the planet from deep space, high impact landing loads and rover operations on the surface of the planet at 8 Torr and -130 C. This paper will present an overview of the test program that included vibration, pyro-shock, landing loads, acoustic noise, thermal vacuum and solar simulation testing at the Jet Propulsion Laboratory (JPL) Environmental Test Laboratory facilities in Pasadena, California.

An approach to developing an integrated pyroprocessing simulator

NASA Astrophysics Data System (ADS)

Lee, Hyo Jik; Ko, Won Il; Choi, Sung Yeol; Kim, Sung Ki; Kim, In Tae; Lee, Han Soo

2014-02-01

Pyroprocessing has been studied for a decade as one of the promising fuel recycling options in Korea. We have built a pyroprocessing integrated inactive demonstration facility (PRIDE) to assess the feasibility of integrated pyroprocessing technology and scale-up issues of the processing equipment. Even though such facility cannot be replaced with a real integrated facility using spent nuclear fuel (SF), many insights can be obtained in terms of the world's largest integrated pyroprocessing operation. In order to complement or overcome such limited test-based research, a pyroprocessing Modelling and simulation study began in 2011. The Korea Atomic Energy Research Institute (KAERI) suggested a Modelling architecture for the development of a multi-purpose pyroprocessing simulator consisting of three-tiered models: unit process, operation, and plant-level-model. The unit process model can be addressed using governing equations or empirical equations as a continuous system (CS). In contrast, the operation model describes the operational behaviors as a discrete event system (DES). The plant-level model is an integrated model of the unit process and an operation model with various analysis modules. An interface with different systems, the incorporation of different codes, a process-centered database design, and a dynamic material flow are discussed as necessary components for building a framework of the plant-level model. As a sample model that contains methods decoding the above engineering issues was thoroughly reviewed, the architecture for building the plant-level-model was verified. By analyzing a process and operation-combined model, we showed that the suggested approach is effective for comprehensively understanding an integrated dynamic material flow. This paper addressed the current status of the pyroprocessing Modelling and simulation activity at KAERI, and also predicted its path forward.

An approach to developing an integrated pyroprocessing simulator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lee, Hyo Jik; Ko, Won Il; Choi, Sung Yeol

Pyroprocessing has been studied for a decade as one of the promising fuel recycling options in Korea. We have built a pyroprocessing integrated inactive demonstration facility (PRIDE) to assess the feasibility of integrated pyroprocessing technology and scale-up issues of the processing equipment. Even though such facility cannot be replaced with a real integrated facility using spent nuclear fuel (SF), many insights can be obtained in terms of the world's largest integrated pyroprocessing operation. In order to complement or overcome such limited test-based research, a pyroprocessing Modelling and simulation study began in 2011. The Korea Atomic Energy Research Institute (KAERI) suggestedmore » a Modelling architecture for the development of a multi-purpose pyroprocessing simulator consisting of three-tiered models: unit process, operation, and plant-level-model. The unit process model can be addressed using governing equations or empirical equations as a continuous system (CS). In contrast, the operation model describes the operational behaviors as a discrete event system (DES). The plant-level model is an integrated model of the unit process and an operation model with various analysis modules. An interface with different systems, the incorporation of different codes, a process-centered database design, and a dynamic material flow are discussed as necessary components for building a framework of the plant-level model. As a sample model that contains methods decoding the above engineering issues was thoroughly reviewed, the architecture for building the plant-level-model was verified. By analyzing a process and operation-combined model, we showed that the suggested approach is effective for comprehensively understanding an integrated dynamic material flow. This paper addressed the current status of the pyroprocessing Modelling and simulation activity at KAERI, and also predicted its path forward.« less

An Integrated Assessment of Location-Dependent Scaling for Microalgae Biofuel Production Facilities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Coleman, Andre M.; Abodeely, Jared; Skaggs, Richard

Successful development of a large-scale microalgae-based biofuels industry requires comprehensive analysis and understanding of the feedstock supply chain—from facility siting/design through processing/upgrading of the feedstock to a fuel product. The evolution from pilot-scale production facilities to energy-scale operations presents many multi-disciplinary challenges, including a sustainable supply of water and nutrients, operational and infrastructure logistics, and economic competitiveness with petroleum-based fuels. These challenges are addressed in part by applying the Integrated Assessment Framework (IAF)—an integrated multi-scale modeling, analysis, and data management suite—to address key issues in developing and operating an open-pond facility by analyzing how variability and uncertainty in space andmore » time affect algal feedstock production rates, and determining the site-specific “optimum” facility scale to minimize capital and operational expenses. This approach explicitly and systematically assesses the interdependence of biofuel production potential, associated resource requirements, and production system design trade-offs. The IAF was applied to a set of sites previously identified as having the potential to cumulatively produce 5 billion-gallons/year in the southeastern U.S. and results indicate costs can be reduced by selecting the most effective processing technology pathway and scaling downstream processing capabilities to fit site-specific growing conditions, available resources, and algal strains.« less

10 CFR 70.62 - Safety program and integrated safety analysis.

Code of Federal Regulations, 2011 CFR

2011-01-01

...) Radiological hazards related to possessing or processing licensed material at its facility; (ii) Chemical hazards of licensed material and hazardous chemicals produced from licensed material; (iii) Facility... performed by a team with expertise in engineering and process operations. The team shall include at least...

Energy Systems Integration Newsletter | Energy Systems Integration Facility

Science.gov Websites

simulated sequences based on a model network. The competitive procurement process provided comparative , procurement help, design reviews, and now construction support. Miramar project support is part of integrated

Integrated Biorefinery Research Facility | Bioenergy | NREL

Science.gov Websites

industrial, two-story building with high-bay, piping, and large processing equipment. Three workers in hard intellectual property and helping industrial partners commercialize technologies. Testing Facilities and

A rapid and highly selective method for the estimation of pyro-, tri- and orthophosphates.

PubMed

Kamat, D R; Savant, V V; Sathyanarayana, D N

1995-03-01

A rapid, highly selective and simple method has been developed for the quantitative determination of pyro-, tri- and orthophosphates. The method is based on the formation of a solid complex of bis(ethylenediamine)cobalt(III) species with pyrophosphate at pH 4.2-4.3, with triphosphate at pH 2.0-2.1 and with orthophosphate at pH 8.2-8.6. The proposed method for pyro- and triphosphates differs from the available method, which is based on the formation of an adduct with tris(ethylenediamine)cobalt(III) species. The complexes have the composition [Co(en)(2)HP(2)O(7)]4H(2)O and [Co(en)(2)H(2)P(3)O(10)]2H(2)O, respectively. The precipitation is instantaneous and quantitative under the recommended optimum conditions giving 99.5% gravimetric yield in both cases. There is no interferences from orthophosphate, trimetaphosphate and pyrophosphate species in the triphosphate estimation up to 5% of each component. The efficacy of the method has been established by determining pyrophosphate and triphosphate contents in various matrices. In the case of orthophosphate, the proposed method differs from the available methods such as ammonium phosphomolybdate, vanadophosphomolybdate and quinoline phosphomolybdate, which are based on the formation of a precipitate, followed by either titrimetry or gravimetry. The precipitation is instantaneous and the method is simple. Under the recommended pH and other reaction conditions, gravimetric yields of 99.6-100% are obtainable. The method is applicable to orthophosphoric acid and a variety of phosphate salts.

Resolving vorticity-driven lateral fire spread using the WRF-Fire coupled atmosphere-fire numerical model

NASA Astrophysics Data System (ADS)

Simpson, C. C.; Sharples, J. J.; Evans, J. P.

2014-09-01

Vorticity-driven lateral fire spread (VLS) is a form of dynamic fire behaviour, during which a wildland fire spreads rapidly across a steep leeward slope in a direction approximately transverse to the background winds. VLS is often accompanied by a downwind extension of the active flaming region and intense pyro-convection. In this study, the WRF-Fire (WRF stands for Weather Research and Forecasting) coupled atmosphere-fire model is used to examine the sensitivity of resolving VLS to both the horizontal and vertical grid spacing, and the fire-to-atmosphere coupling from within the model framework. The atmospheric horizontal and vertical grid spacing are varied between 25 and 90 m, and the fire-to-atmosphere coupling is either enabled or disabled. At high spatial resolutions, the inclusion of fire-to-atmosphere coupling increases the upslope and lateral rate of spread by factors of up to 2.7 and 9.5, respectively. This increase in the upslope and lateral rate of spread diminishes at coarser spatial resolutions, and VLS is not modelled for a horizontal and vertical grid spacing of 90 m. The lateral fire spread is driven by fire whirls formed due to an interaction between the background winds and the vertical circulation generated at the flank of the fire front as part of the pyro-convective updraft. The laterally advancing fire fronts become the dominant contributors to the extreme pyro-convection. The results presented in this study demonstrate that both high spatial resolution and two-way atmosphere-fire coupling are required to model VLS with WRF-Fire.

Recovery Act: Beneficial CO{sub 2} Capture in an Integrated Algal Biorefinery for Renewable Generation and Transportation Fuels

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lane, Christopher; Hampel, Kristin; Rismani-Yazdi, Hamid

DOE DE-FE0001888 Award, Phase 2, funded research, development, and deployment (RD&D) of Phycal’s pilot-scale, algae to biofuels, bioproducts, and processing facility in Hawai’i. Phycal’s algal-biofuel and bioproducts production system integrates several novel and mature technologies into a system that captures and reuses industrially produced carbon dioxide emissions, which would otherwise go directly to the atmosphere, for the manufacture of renewable energy products and bioproducts from algae (note that these algae are not genetically engineered). At the end of Phase 2, the project as proposed was to encompass 34 acres in Central Oahu and provide large open ponds for algal massmore » culturing, heterotrophic reactors for the Heteroboost™ process, processing facilities, water recycling facilities, anaerobic digestion facilities, and other integrated processes. The Phase 2 award was divided into two modules, Modules 1 & 2, where the Module 1 effort addressed critical scaling issues, tested highest risk technologies, and set the overall infrastructure needed for a Module 2. Phycal terminated the project prior to executing construction of the first Module. This Final Report covers the development research, detailed design, and the proposed operating strategy for Module 1 of Phase 2.« less

PIMS sequencing extension: a laboratory information management system for DNA sequencing facilities.

PubMed

Troshin, Peter V; Postis, Vincent Lg; Ashworth, Denise; Baldwin, Stephen A; McPherson, Michael J; Barton, Geoffrey J

2011-03-07

Facilities that provide a service for DNA sequencing typically support large numbers of users and experiment types. The cost of services is often reduced by the use of liquid handling robots but the efficiency of such facilities is hampered because the software for such robots does not usually integrate well with the systems that run the sequencing machines. Accordingly, there is a need for software systems capable of integrating different robotic systems and managing sample information for DNA sequencing services. In this paper, we describe an extension to the Protein Information Management System (PIMS) that is designed for DNA sequencing facilities. The new version of PIMS has a user-friendly web interface and integrates all aspects of the sequencing process, including sample submission, handling and tracking, together with capture and management of the data. The PIMS sequencing extension has been in production since July 2009 at the University of Leeds DNA Sequencing Facility. It has completely replaced manual data handling and simplified the tasks of data management and user communication. Samples from 45 groups have been processed with an average throughput of 10000 samples per month. The current version of the PIMS sequencing extension works with Applied Biosystems 3130XL 96-well plate sequencer and MWG 4204 or Aviso Theonyx liquid handling robots, but is readily adaptable for use with other combinations of robots. PIMS has been extended to provide a user-friendly and integrated data management solution for DNA sequencing facilities that is accessed through a normal web browser and allows simultaneous access by multiple users as well as facility managers. The system integrates sequencing and liquid handling robots, manages the data flow, and provides remote access to the sequencing results. The software is freely available, for academic users, from http://www.pims-lims.org/.

Enhanced Risk of Wildfire Resulting from the Interactions between Pyro-Cumulus and Mountain Waves: Implications for Fire Research and Management

NASA Astrophysics Data System (ADS)

Kim, Y. J.; Linn, R.; Sauer, J.; Canfield, J.; Costigan, K. R.; Munoz-Esparza, D.

2014-12-01

The Los Alamos National Laboratory is conducting a research project to understand the physical mechanisms behind the Las Conchas Fire that occurred in Santa Fe National Forest near Los Alamos, New Mexico on June 26, 2011. Between 8 pm on June 26 and 3 am on June 27, the fire grew from 8,000 to 43,000 acres, spreading downhill in sparse fuels and lighter winds than were present during the first several hours of the fire. Fire behavior experts and fire management officers expected the fire to reach 9,000 to 12,000 acres by sunrise due to the anticipated burning conditions, but it actually increased 440% in size before 3 am, surprising everyone. One viable hypothesis was suggested for this baffling fire behavior: a partial collapse of the soot-laden pyrocumulus column (pyro-cu) that towered above the fire, causing a sustained density current carrying fire at high speed. Moreover, another mechanism has been suggested recently that could have significantly affected the fire characteristics around mountainous regions, such as Jemez Mountains near Los Alamos: the drastic changes in the speed, direction, and gustiness of the winds due to the development of mountain waves. The present research tests these hypotheses and attempts to decipher the combination of environmental conditions, due to pyro-cu and mountain wave interactions, and fire behavior dynamics associated with this anomalous wildfire event. Preliminary results from WRF (Weather Research and Forecasting model) and HIGRAD (High-GRADient model developed at LANL) simulations suggest that these two mechanisms may need to be taken into account in order to fully understand and prepare for atypical wildfire behavior in regions with complex topography. It is possible that the Las Conchas Fire could have directly affected the nearby Los Alamos National Laboratory if the fire broke out concurrently with both pyro-cu and strong mountain waves along the upstream of the Laboratory. This research also addresses its implications for the management as well as the research of wildfire in that, in order to prepare for potential wildfire, the topography of the surrounding region as well as the region of importance itself should be taken into account.

Mineralogical Characterization of Copper Slag from Tongling Nonferrous Metals Group China

NASA Astrophysics Data System (ADS)

Chun, Tiejun; Ning, Chao; Long, Hongming; Li, Jiaxin; Yang, Jialong

2016-09-01

In this paper, the mineralogical characterization of typical copper slag supplied by the Tongling Nonferrous Metals Group China was performed based on x-ray fluorescence, x-ray diffraction, and scanning electron microscopy with energy dispersive spectroscopy. The results show that the dominant phases of the slag are fayalite, glassy substance and magnetite. The minor accessory phases consist of copper matte, metallic copper and other complex lead and zinc minerals. The contents of iron, copper, lead and zinc in copper slag are 40.21%, 0.79%, 0.24%, and 2.80%, respectively. The mineralogy of copper slag indicates that these valuable elements are difficult to recover by beneficiation processes due to the complicated occurrences. Instead, the pyro-metallurgical processes appear promising in recovering the valuable metals from copper slag.

Human Engineering Operations and Habitability Assessment: A Process for Advanced Life Support Ground Facility Testbeds

NASA Technical Reports Server (NTRS)

Connolly, Janis H.; Arch, M.; Elfezouaty, Eileen Schultz; Novak, Jennifer Blume; Bond, Robert L. (Technical Monitor)

1999-01-01

Design and Human Engineering (HE) processes strive to ensure that the human-machine interface is designed for optimal performance throughout the system life cycle. Each component can be tested and assessed independently to assure optimal performance, but it is not until full integration that the system and the inherent interactions between the system components can be assessed as a whole. HE processes (which are defining/app lying requirements for human interaction with missions/systems) are included in space flight activities, but also need to be included in ground activities and specifically, ground facility testbeds such as Bio-Plex. A unique aspect of the Bio-Plex Facility is the integral issue of Habitability which includes qualities of the environment that allow humans to work and live. HE is a process by which Habitability and system performance can be assessed.

Fluids and Combustion Facility Acoustic Emissions Controlled by Aggressive Low-Noise Design Process

NASA Technical Reports Server (NTRS)

Cooper, Beth A.; Young, Judith A.

2004-01-01

The Fluids and Combustion Facility (FCF) is a dual-rack microgravity research facility that is being developed by Northrop Grumman Information Technology (NGIT) for the International Space Station (ISS) at the NASA Glenn Research Center. As an on-orbit test bed, FCF will host a succession of experiments in fluid and combustion physics. The Fluids Integrated Rack (FIR) and the Combustion Integrated Rack (CIR) must meet ISS acoustic emission requirements (ref. 1), which support speech communication and hearing-loss-prevention goals for ISS crew. To meet these requirements, the NGIT acoustics team implemented an aggressive low-noise design effort that incorporated frequent acoustic emission testing for all internal noise sources, larger-scale systems, and fully integrated racks (ref. 2). Glenn's Acoustical Testing Laboratory (ref. 3) provided acoustical testing services (see the following photograph) as well as specialized acoustical engineering support as part of the low-noise design process (ref. 4).

NIST: Information Management in the AMRF

NASA Technical Reports Server (NTRS)

Callaghan, George (Editor)

1991-01-01

The information management strategies developed for the NIST Automated Manufacturing Research Facility (AMRF) - a prototype small batch manufacturing facility used for integration and measurement related standards research are outlined in this video. The five major manufacturing functions - design, process planning, off-line programming, shop floor control, and materials processing are explained and their applications demonstrated.

Reduction of environmental and energy footprint of microalgal biodiesel production through material and energy integration.

PubMed

Chowdhury, Raja; Viamajala, Sridhar; Gerlach, Robin

2012-03-01

The life cycle impacts were assessed for an integrated microalgal biodiesel production system that facilitates energy- and nutrient- recovery through anaerobic digestion, and utilizes glycerol generated within the facility for additional heterotrophic biodiesel production. Results show that when external fossil energy inputs are lowered through process integration, the energy demand, global warming potential (GWP), and process water demand decrease significantly and become less sensitive to algal lipid content. When substitution allocation is used to assign additional credit for avoidance of fossil energy use (through utilization of recycled nutrients and biogas), GWP and water demand can, in fact, increase with increase in lipid content. Relative to stand-alone algal biofuel facilities, energy demand can be lowered by 3-14 GJ per ton of biodiesel through process integration. GWP of biodiesel from the integrated system can be lowered by up to 71% compared to petroleum fuel. Evaporative water loss was the primary water demand driver. Copyright © 2011 Elsevier Ltd. All rights reserved.

Liquid rocket booster integration study. Volume 1: Executive summary

NASA Technical Reports Server (NTRS)

1988-01-01

The impacts of introducing liquid rocket booster engines (LRB) into the Space Transportation System (STS)/Kennedy Space Center (KSC) launch environment are identified and evaluated. Proposed ground systems configurations are presented along with a launch site requirements summary. Prelaunch processing scenarios are described and the required facility modifications and new facility requirements are analyzed. Flight vehicle design recommendations to enhance launch processing are discussed. Processing approaches to integrate LRB with existing STS launch operations are evaluated. The key features and significance of launch site transition to a new STS configuration in parallel with ongoing launch activities are enumerated. This volume is the executive summary of the five volume series.

Liquid rocket booster integration study. Volume 5, part 1: Appendices

NASA Technical Reports Server (NTRS)

1988-01-01

The impacts of introducing liquid rocket booster engines (LRB) into the Space Transportation System (STS)/Kennedy Space Center (KSC) launch environment are identified and evaluated. Proposed ground systems configurations are presented along with a launch site requirements summary. Prelaunch processing scenarios are described and the required facility modifications and new facility requirements are analyzed. Flight vehicle design recommendations to enhance launch processing are discussed. Processing approaches to integrate LRB with existing STS launch operations are evaluated. The key features and significance of launch site transition to a new STS configuration in parallel with ongoing launch activities are enumerated. This volume is the appendices of the five volume series.

Liquid Rocket Booster Integration Study. Volume 2: Study synopsis

NASA Technical Reports Server (NTRS)

1988-01-01

The impacts of introducing liquid rocket booster engines (LRB) into the Space Transportation System (STS)/Kennedy Space Center (KSC) launch environment are identified and evaluated. Proposed ground systems configurations are presented along with a launch site requirements summary. Prelaunch processing scenarios are described and the required facility modifications and new facility requirements are analyzed. Flight vehicle design recommendations to enhance launch processing are discussed. Processing approaches to integrate LRB with existing STS launch operations are evaluated. The key features and significance of launch site transition to a new STS configuration in parallel with ongoing launch activities are enumerated. This volume is the study summary of the five volume series.

Rockot Launch Vehicle Commercial Operations for Grace and Iridium Program

NASA Astrophysics Data System (ADS)

Viertel, Y.; Kinnersley, M.; Schumacher, I.

2002-01-01

The GRACE mission and the IRIDIUM mission on ROCKOT launch vehicle are presented. Two identical GRACE satellites to measure in tandem the gravitational field of the earth with previously unattainable accuracy - it's called the Gravity Research and Climate Experiment, or and is a joint project of the U.S. space agency, NASA and the German Centre for Aeronautics and Space Flight, DLR. In order to send the GRACE twins into a 500x500 km , 89deg. orbit, the Rockot launch vehicle was selected. A dual launch of two Iridium satellites was scheduled for June 2002 using the ROCKOT launch vehicle from Plesetsk Cosmodrome in Northern Russia. This launch will inject two replacement satellites into a low earth orbit (LEO) to support the maintenance of the Iridium constellation. In September 2001, Eurockot successfully carried out a "Pathfinder Campaign" to simulate the entire Iridium mission cycle at Plesetsk. The campaign comprised the transport of simulators and related equipment to the Russian port-of-entry and launch site and also included the integration and encapsulation of the simulators with the actual Rockot launch vehicle at Eurockot's dedicated launch facilities at Plesetsk Cosmodrome. The pathfinder campaign lasted four weeks and was carried out by a joint team that also included Khrunichev, Russian Space Forces and Eurockot personnel on the contractors' side. The pathfinder mission confirmed the capability of Eurockot Launch Services to perform the Iridium launch on cost and on schedule at Plesetsk following Eurockot's major investment in international standard preparation, integration and launch facilities including customer facilities and a new hotel. In 2003, Eurockot will also launch the Japanese SERVI'S-1 satellite for USEF. The ROCKOT launch vehicle is a 3 stage liquid fuel rocket whose first 2 stages have been adapted from the Russian SS-19. A third stage, called "Breeze", can be repeatedly ignited and is extraordinarily capable of manoeuvre. Rockot can place payloads of up to 1900 kilograms in near- earth orbit. The rocket is 29 meters long with a diameter of 2.5 meters. The launch weight is about 107 tons. Satellite launches with Rockot are a service offered and carried out by Eurockot Launch Service GmbH. It is a European Russian joint venture which is 51% controlled by Astrium and 49 % by Khrunichev, Russia's leading launch vehicle firm. The Rockot vehicles can be launched from Plesetsk in northern Russia and Baikonur in Kazakhstan. EUROCKOT provides a wide choice of flight-proven adapters and multi-satellite platforms to the customer to allow such payloads to be accommodated. These range from the Russian Single Pyro Point Attachment System (SPPA)

Resolving vorticity-driven lateral fire spread using the WRF-Fire coupled atmosphere-fire numerical model

NASA Astrophysics Data System (ADS)

Simpson, C. C.; Sharples, J. J.; Evans, J. P.

2014-05-01

Fire channelling is a form of dynamic fire behaviour, during which a wildland fire spreads rapidly across a steep lee-facing slope in a direction transverse to the background winds, and is often accompanied by a downwind extension of the active flaming region and extreme pyro-convection. Recent work using the WRF-Fire coupled atmosphere-fire model has demonstrated that fire channelling can be characterised as vorticity-driven lateral fire spread (VDLS). In this study, 16 simulations are conducted using WRF-Fire to examine the sensitivity of resolving VDLS to spatial resolution and atmosphere-fire coupling within the WRF-Fire model framework. The horizontal grid spacing is varied between 25 and 90 m, and the two-way atmosphere-fire coupling is either enabled or disabled. At high spatial resolution, the atmosphere-fire coupling increases the peak uphill and lateral spread rate by a factor of up to 2.7 and 9.5. The enhancement of the uphill and lateral spread rate diminishes at coarser spatial resolution, and VDLS is not modelled for a horizontal grid spacing of 90 m. The laterally spreading fire fronts become the dominant contributors of the extreme pyro-convection. The resolved fire-induced vortices responsible for driving the lateral spread in the coupled simulations have non-zero vorticity along each unit vector direction, and develop due to an interaction between the background winds and vertical return circulations generated at the flank of the fire front as part of the pyro-convective updraft. The results presented in this study demonstrate that both high spatial resolution and two-way atmosphere-fire coupling are required to reproduce VDLS within the current WRF-Fire model framework.

40 CFR 419.50 - Applicability; description of the integrated subcategory.

Code of Federal Regulations, 2011 CFR

2011-07-01

... topping, cracking, lube oil manufacturing processes, and petrochemical operations, whether or not the facility includes any process in addition to topping, cracking, lube oil manufacturing processes, and...

40 CFR 419.50 - Applicability; description of the integrated subcategory.

Code of Federal Regulations, 2010 CFR

2010-07-01

... topping, cracking, lube oil manufacturing processes, and petrochemical operations, whether or not the facility includes any process in addition to topping, cracking, lube oil manufacturing processes, and...

Integrating biomedical and herbal medicine in Ghana - experiences from the Kumasi South Hospital: a qualitative study.

PubMed

Boateng, Millicent Addai; Danso-Appiah, Anthony; Turkson, Bernard Kofi; Tersbøl, Britt Pinkowski

2016-07-07

Over the past decade there has been growing interest in the use of herbal medicine both in developed and developing countries. Given the high proportion of patients using herbal medicine in Ghana, some health facilities have initiated implementation of herbal medicine as a component of their healthcare delivery. However, the extent to which herbal medicine has been integrated in Ghanaian health facilities, how integration is implemented and perceived by different stakeholders has not been documented. The study sought to explore these critical issues at the Kumasi South Hospital (KSH) and outline the challenges and motivations of the integration process. Qualitative phenomenological exploratory study design involving fieldwork observations, focus group discussion, in-depth interviews and key informants' interviews was employed to collect data. Policies and protocols outlining the definition, process and goals of integration were lacking, with respondents sharing different views about the purpose and value of integration of herbal medicine within public health facilities. Key informants were supportive of the initiative. Whilst biomedical health workers perceived the system to be parallel than integrated, health personnel providing herbal medicine perceived the system as integrated. Most patients were not aware of the herbal clinic in the hospital but those who had utilized services of the herbal clinic viewed the clinic as part of the hospital. The lack of a regulatory policy and protocol for the integration seemed to have led to the different perception of the integration. Policy and protocol to guide the integration are key recommendations.

Development of a neutron measurement system in unified non-destructive assay for the PRIDE facility

NASA Astrophysics Data System (ADS)

Seo, Hee; Park, Se-Hwan; Won, Byung-Hee; Ahn, Seong-Kyu; Shin, Hee-Sung; Na, Sang-Ho; Song, Dae-Yong; Kim, Ho-Dong; Lee, Seung Kyu

2013-12-01

The Korea Atomic Energy Research Institute (KAERI) has made an effort to develop pyroprocessing technology to resolve an on-going problem in Korea, i.e., the management of spent nuclear fuels. To this end, a test-bed facility for pyroprocessing, called PRIDE (PyRoprocessing Integrated inactive DEmonstration facility), is being constructed at KAERI. The main objective of PRIDE is to evaluate the performance of the unit processes, remote operation, maintenance, and proliferation resistance. In addition, integrating all unit processes into a one-step process is also one of the main goals. PRIDE can also provide a good opportunity to test safeguards instrumentations for a pyroprocessing facility such as nuclear material accounting devices, surveillance systems, radiation monitoring systems, and process monitoring systems. In the present study, a non-destructive assay (NDA) system for the testing of nuclear material accountancy of PRIDE was designed by integrating three different NDA techniques, i.e., neutron, gamma-ray, and mass measurements. The developed neutron detection module consists of 56 3He tubes and 16 AMPTEK A111 signal processing circuits. The amplifiers were matched in terms of the gain and showed good uniformity after a gain-matching procedure (%RSD=0.37%). The axial and the radial efficiency distributions within the cavity were then measured using a 252Cf neutron source and were compared with the MCNPX calculation results. The measured efficiency distributions showed excellent agreement with the calculations, which confirmed the accuracy of the MCNPX model of the system.

Preliminary technical data summary No. 3 for the Defense Waste Processing Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Landon, L.F.

1980-05-01

This document presents an update on the best information presently available for the purpose of establishing the basis for the design of a Defense Waste Processing Facility. Objective of this project is to provide a facility to fix the radionuclides present in Savannah River Plant (SRP) high-level liquid waste in a high-integrity form (glass). Flowsheets and material balances reflect the alternate CAB case including the incorporation of low-level supernate in concrete. (DLC)

Modeling integrated biomass gasification business concepts

Treesearch

Peter J. Ince; Ted Bilek; Mark A. Dietenberger

2011-01-01

Biomass gasification is an approach to producing energy and/or biofuels that could be integrated into existing forest product production facilities, particularly at pulp mills. Existing process heat and power loads tend to favor integration at existing pulp mills. This paper describes a generic modeling system for evaluating integrated biomass gasification business...

Characterization of fatty acid-producing wastewater microbial communities using next generation sequencing technologies

EPA Science Inventory

While wastewater represents a viable source of bacterial biodiesel production, very little is known on the composition of these microbial communities. We studied the taxonomic diversity and succession of microbial communities in bioreactors accumulating fatty acids using 454-pyro...

Ferroic Shape Memory Materials & Piezo:Pyro-Electric Oriented Recrystallized Glasses.

DTIC Science & Technology

1986-07-01

microcope hot stage. The direction of crystallization was parallel to the direction of temperature gradient. The crystalline phases in the glass...may increase or decrease with temperature. Several compounds show a sign reversal in the pyroelectric coefficients, going from positive to negative

Galileo spacecraft power management and distribution system

NASA Technical Reports Server (NTRS)

Detwiler, R. C.; Smith, R. L.

1990-01-01

The Galileo PMAD (power management and distribution system) is described, and the design drivers that established the final as-built hardware are discussed. The spacecraft is powered by two general-purpose heat-source-radioisotope thermoelectric generators. Power bus regulation is provided by a shunt regulator. Galileo PMAD distributes a 570-W beginning of mission (BOM) power source to a user complement of some 137 load elements. Extensive use of pyrotechnics requires two pyro switching subassemblies. They initiate 148 squibs which operate the 47 pyro devices on the spacecraft. Detection and correction of faults in the Galileo PMAD is an autonomous feature dictated by requirements for long life and reliability in the absence of ground-based support. Volatile computer memories in the spacecraft command and data system and attitude control system require a continuous source of backup power during all anticipated power bus fault scenarios. Power for the Jupiter Probe is conditioned, isolated, and controlled by a Probe interface subassembly. Flight performance of the spacecraft and the PMAD has been successful to date, with no major anomalies.

The SSMEPF opens with a ribbon-cutting ceremony

NASA Technical Reports Server (NTRS)

1998-01-01

Participants in the ribbon cutting for KSC's new 34,600-square- foot Space Shuttle Main Engine Processing Facility (SSMEPF) gather to talk inside the facility following the ceremony. From left, they are Robert B. Sieck, director of Shuttle Processing; KSC Center Director Roy D. Bridges Jr.; U.S. Congressman Dave Weldon; John Plowden, vice president of Rocketdyne; and Donald R. McMonagle, manager of Launch Integration. A major addition to the existing Orbiter Processing Facility Bay 3, the SSMEPF replaces the Shuttle Main Engine Shop located in the Vehicle Assembly Building (VAB). The decision to move the shop out of the VAB was prompted by safety considerations and recent engine processing improvements. The first three main engines to be processed in the new facility will fly on Shuttle Endeavour's STS-88 mission in December 1998.

Liquid rocket booster integration study. Volume 3: Study products. Part 2: Sections 8-19

NASA Technical Reports Server (NTRS)

1988-01-01

The impacts of introducing liquid rocket booster engines (LRB) into the Space Transportation System (STS)/Kennedy Space Center (KSC) launch environment are identified and evaluated. Proposed ground systems configurations are presented along with a launch site requirements summary. Prelaunch processing scenarios are described and the required facility modifications and new facility requirements are analyzed. Flight vehicle design recommendations to enhance launch processing are discussed. Processing approaches to integrate LRB with existing STS launch operations are evaluated. The key features and significance of launch site transition to a new STS configuration in parallel with ongoing launch activities are enumerated. This volume is part two of the study products section of the five volume series.

Liquid rocket booster integration study. Volume 3, part 1: Study products

NASA Technical Reports Server (NTRS)

1988-01-01

The impacts of introducing liquid rocket booster engines (LRB) into the Space Transportation System (STS)/Kennedy Space Center (KSC) launch environment are identified and evaluated. Proposed ground systems configurations are presented along with a launch site requirements summary. Prelaunch processing scenarios are described and the required facility modifications and new facility requirements are analyzed. Flight vehicle design recommendations to enhance launch processing are discussed. Processing approaches to integrate LRB with existing STS launch operations are evaluated. The key features and significance of launch site transition to a new STS configuration in parallel with ongoing launch activities are enumerated. This volume is part one of the study products section of the five volume series.

PIMS sequencing extension: a laboratory information management system for DNA sequencing facilities

PubMed Central

2011-01-01

Background Facilities that provide a service for DNA sequencing typically support large numbers of users and experiment types. The cost of services is often reduced by the use of liquid handling robots but the efficiency of such facilities is hampered because the software for such robots does not usually integrate well with the systems that run the sequencing machines. Accordingly, there is a need for software systems capable of integrating different robotic systems and managing sample information for DNA sequencing services. In this paper, we describe an extension to the Protein Information Management System (PIMS) that is designed for DNA sequencing facilities. The new version of PIMS has a user-friendly web interface and integrates all aspects of the sequencing process, including sample submission, handling and tracking, together with capture and management of the data. Results The PIMS sequencing extension has been in production since July 2009 at the University of Leeds DNA Sequencing Facility. It has completely replaced manual data handling and simplified the tasks of data management and user communication. Samples from 45 groups have been processed with an average throughput of 10000 samples per month. The current version of the PIMS sequencing extension works with Applied Biosystems 3130XL 96-well plate sequencer and MWG 4204 or Aviso Theonyx liquid handling robots, but is readily adaptable for use with other combinations of robots. Conclusions PIMS has been extended to provide a user-friendly and integrated data management solution for DNA sequencing facilities that is accessed through a normal web browser and allows simultaneous access by multiple users as well as facility managers. The system integrates sequencing and liquid handling robots, manages the data flow, and provides remote access to the sequencing results. The software is freely available, for academic users, from http://www.pims-lims.org/. PMID:21385349

FY 2011 Educational Facilities Master Plan & the FY 2011-2016 Capital Improvements Program

ERIC Educational Resources Information Center

Montgomery County Public Schools, 2010

2010-01-01

The FY 2011 Educational Facilities Master Plan (Master Plan) and FY 2011-2016 Capital Improvements Program (CIP) reflect the adopted actions of the Montgomery County (Maryland) Council and integrate the facilities planning process with the annual capital budget and the six-year CIP. The CIP is developed in accordance with the Board of Education…

Small Projects Rapid Integration and Test Environment (SPRITE): Application for Increasing Robustness

NASA Technical Reports Server (NTRS)

Rakoczy, John; Heater, Daniel; Lee, Ashley

2013-01-01

Marshall Space Flight Center's (MSFC) Small Projects Rapid Integration and Test Environment (SPRITE) is a Hardware-In-The-Loop (HWIL) facility that provides rapid development, integration, and testing capabilities for small projects (CubeSats, payloads, spacecraft, and launch vehicles). This facility environment focuses on efficient processes and modular design to support rapid prototyping, integration, testing and verification of small projects at an affordable cost, especially compared to larger type HWIL facilities. SPRITE (Figure 1) consists of a "core" capability or "plant" simulation platform utilizing a graphical programming environment capable of being rapidly re-configured for any potential test article's space environments, as well as a standard set of interfaces (i.e. Mil-Std 1553, Serial, Analog, Digital, etc.). SPRITE also allows this level of interface testing of components and subsystems very early in a program, thereby reducing program risk.

NASA Langley Research Center's Simulation-To-Flight Concept Accomplished through the Integration Laboratories of the Transport Research Facility

NASA Technical Reports Server (NTRS)

Martinez, Debbie; Davidson, Paul C.; Kenney, P. Sean; Hutchinson, Brian K.

2004-01-01

The Flight Simulation and Software Branch (FSSB) at NASA Langley Research Center (LaRC) maintains the unique national asset identified as the Transport Research Facility (TRF). The TRF is a group of facilities and integration laboratories utilized to support the LaRC's simulation-to-flight concept. This concept incorporates common software, hardware, and processes for both groundbased flight simulators and LaRC s B-757-200 flying laboratory identified as the Airborne Research Integrated Experiments System (ARIES). These assets provide Government, industry, and academia with an efficient way to develop and test new technology concepts to enhance the capacity, safety, and operational needs of the ever-changing national airspace system. The integration of the TRF enables a smooth continuous flow of the research from simulation to actual flight test.

Spacelab Data Processing Facility (SLDPF) quality assurance expert systems development

NASA Technical Reports Server (NTRS)

Basile, Lisa R.; Kelly, Angelita C.

1987-01-01

The Spacelab Data Processing Facility (SLDPF) is an integral part of the Space Shuttle data network for missions that involve attached scientific payloads. Expert system prototypes were developed to aid in the performance of the quality assurance function of the Spacelab and/or Attached Shuttle Payloads processed telemetry data. The Spacelab Input Processing System (SIPS) and the Spacelab Output Processing System (SOPS), two expert systems, were developed to determine their feasibility and potential in the quality assurance of processed telemetry data. The capabilities and performance of these systems are discussed.

Neutron radiography in Indian space programme

NASA Astrophysics Data System (ADS)

Viswanathan, K.

1999-11-01

Pyrotechnic devices are indispensable in any space programme to perform such critical operations as ignition, stage separation, solar panel deployment, etc. The nature of design and configuration of different types of pyrotechnic devices, and the type of materials that are put in their construction make the inspection of them with thermal neutrons more favourable than any other non destructive testing methods. Although many types of neutron sources are available for use, generally the radiographic quality/exposure duration and cost of source run in opposite directions even after four decades of research and development. But in the area of space activity, by suitably combining the X-ray and neutron radiographic requirements, the inspection of the components can be made economically viable. This is demonstrated in the Indian space programme by establishing a 15 MeV linear accelerator based neutron generator facility to inspect medium to giant solid propellant boosters by X-ray inspection and all types of critical pyro and some electronic components by neutron radiography. Since the beam contains unacceptable gamma, transfer imaging technique has been evolved and the various parameters have been optimised to get a good quality image.

Towards the Integration of APECS with VE-Suite to Create a Comprehensive Virtual Engineering Environment

DOE Office of Scientific and Technical Information (OSTI.GOV)

McCorkle, D.; Yang, C.; Jordan, T.

2007-06-01

Modeling and simulation tools are becoming pervasive in the process engineering practice of designing advanced power generation facilities. These tools enable engineers to explore many what-if scenarios before cutting metal or constructing a pilot scale facility. While such tools enable investigation of crucial plant design aspects, typical commercial process simulation tools such as Aspen Plus®, gPROMS®, and HYSYS® still do not explore some plant design information, including computational fluid dynamics (CFD) models for complex thermal and fluid flow phenomena, economics models for policy decisions, operational data after the plant is constructed, and as-built information for use in as-designed models. Softwaremore » tools must be created that allow disparate sources of information to be integrated if environments are to be constructed where process simulation information can be accessed. At the Department of Energy’s (DOE) National Energy Technology Laboratory (NETL), the Advanced Process Engineering Co-Simulator (APECS) has been developed as an integrated software suite that combines process simulation (e.g., Aspen Plus) and high-fidelity equipment simulation (e.g., Fluent® CFD), together with advanced analysis capabilities including case studies, sensitivity analysis, stochastic simulation for risk/uncertainty analysis, and multi-objective optimization. In this paper, we discuss the initial phases of integrating APECS with the immersive and interactive virtual engineering software, VE-Suite, developed at Iowa State University and Ames Laboratory. VE-Suite utilizes the ActiveX (OLE Automation) controls in Aspen Plus wrapped by the CASI library developed by Reaction Engineering International to run the process simulation and query for unit operation results. This integration permits any application that uses the VE-Open interface to integrate with APECS co-simulations, enabling construction of the comprehensive virtual engineering environment needed for the rapid engineering of advanced power generation facilities.« less

Commercial-scale demonstration of the Liquid Phase Methanol process. Technical progress report number 8, April 1--June 30, 1996

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-12-31

The project involves the construction of an 80,000 gallon per day (260 tons per day (TPD)) methanol unit utilizing coal-derived synthesis gas from Eastman`s integrated coal gasification facility. The new equipment consists of synthesis gas feed preparation and compression facilities, the liquid phase reactor and auxiliaries, product distillation facilities, and utilities. The technology to be demonstrated is the product of a cooperative development effort by Air Products and DOE in a program that started in 1981. Developed to enhance electric power generation using integrated gasification combined cycle (IGCC) technology, the LPMEOH{trademark} process is ideally suited for directly processing gases producedmore » by modern-day coal gasifiers. Originally tested at a small (10 TPD), DOE-owned experimental unit in LaPorte, Texas, the technology provides several improvements essential for the economic coproduction of methanol and electricity directly from gasified coal. This liquid phase process suspends fine catalyst particles in an inert liquid, forming a slurry. The slurry dissipates the heat of the chemical reaction away from the catalyst surface, protecting the catalyst and allowing the methanol synthesis reaction to proceed at higher rates. At the Eastman complex, the technology is being integrated with existing coal-gasifiers. A carefully developed test plan will allow operations at Eastman to simulate electricity demand load-following in coal-based IGCC facilities. The operations will also demonstrate the enhanced stability and heat dissipation of the conversion process, its reliable on/off operation, and its ability to produce methanol as a clean liquid fuel without additional upgrading.« less

LIFE-CYCLE IMPACT ASSESSMENT DEMONSTRATION FOR THE GBU-24

EPA Science Inventory

The primary goal of this project was to develop and demonstrate a life-cycle impact assessment (LCIA) approach using existing life-cycle inventory (LCI) data on one of the propellants, energetics, and pyro-technic (PEP) materials of interest to the U.S. Department of Defense (DoD...

Providing security for automated process control systems at hydropower engineering facilities

NASA Astrophysics Data System (ADS)

Vasiliev, Y. S.; Zegzhda, P. D.; Zegzhda, D. P.

2016-12-01

This article suggests the concept of a cyberphysical system to manage computer security of automated process control systems at hydropower engineering facilities. According to the authors, this system consists of a set of information processing tools and computer-controlled physical devices. Examples of cyber attacks on power engineering facilities are provided, and a strategy of improving cybersecurity of hydropower engineering systems is suggested. The architecture of the multilevel protection of the automated process control system (APCS) of power engineering facilities is given, including security systems, control systems, access control, encryption, secure virtual private network of subsystems for monitoring and analysis of security events. The distinctive aspect of the approach is consideration of interrelations and cyber threats, arising when SCADA is integrated with the unified enterprise information system.

Systems integration of marketable subsystems: A collection of progress reports

NASA Technical Reports Server (NTRS)

1978-01-01

Monthly progress reports are given in the areas of marketable subsystems integration; development, design, and building of site data acquisition subsystems and data processing systems; operation of the solar test facility and a systems analysis.

FY 2013 Educational Facilities Master Plan and the FY 2013-2018 Capital Improvements Program

ERIC Educational Resources Information Center

Montgomery County Public Schools, 2012

2012-01-01

The FY 2013 Educational Facilities Master Plan (Master Plan) and the FY 2013-2018 Capital Improvements Program (CIP) reflect the adopted actions of the Montgomery County (Maryland) Council and integrate the facilities planning process with the annual capital budget and the six-year CIP. The CIP is developed in accordance with the Board of…

FY 2012 Educational Facilities Master Plan and the Amended FY 2011-2016 Capital Improvements Program

ERIC Educational Resources Information Center

Montgomery County Public Schools, 2011

2011-01-01

The FY 2012 Educational Facilities Master Plan (Master Plan) and Amendments to the FY 2011-2016 Capital Improvements Program (CIP) reflect the adopted actions of the Montgomery County (Maryland) Council and integrate the facilities planning process with the annual capital budget and the six-year CIP. The CIP is developed in accordance with the…

Supporting NASA Facilities Through GIS

NASA Technical Reports Server (NTRS)

Ingham, Mary E.

2000-01-01

The NASA GIS Team supports NASA facilities and partners in the analysis of spatial data. Geographic Information System (G[S) is an integration of computer hardware, software, and personnel linking topographic, demographic, utility, facility, image, and other geo-referenced data. The system provides a graphic interface to relational databases and supports decision making processes such as planning, design, maintenance and repair, and emergency response.

FY 2007 Educational Facilities Master Plan and the FY 2007-2012 Capital Improvements Program

ERIC Educational Resources Information Center

Montgomery County Public Schools, 2006

2006-01-01

The FY 2007 Educational Facilities Master Plan (Master Plan) and FY 2007-2012 Capital Improvements Program (CIP) reflect the adopted actions of the Montgomery County (Maryland) Council and integrate the facilities planning process with the annual capital budget and the six-year CIP. The CIP is developed in accordance with the Board of Education…

Evaluation of mercury in the liquid waste processing facilities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jain, Vijay; Shah, Hasmukh; Occhipinti, John E.

2015-08-13

This report provides a summary of Phase I activities conducted to support an Integrated Evaluation of Mercury in Liquid Waste System (LWS) Processing Facilities. Phase I activities included a review and assessment of the liquid waste inventory and chemical processing behavior of mercury using a system by system review methodology approach. Gaps in understanding mercury behavior as well as action items from the structured reviews are being tracked. 64% of the gaps and actions have been resolved.

Low Cost Solar Array Project. Feasibility of the silane process for producing semiconductor-grade silicon. Final report, October 1975-March 1979

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1979-06-01

The commercial production of low-cost semiconductor-grade silicon is an essential requirement of the JPL/DOE (Department of Energy) Low-Cost Solar Array (LSA) Project. A 1000-metric-ton-per-year commercial facility using the Union Carbide Silane Process will produce molten silicon for an estimated price of $7.56/kg (1975 dollars, private financing), meeting the DOE goal of less than $10/kg. Conclusions and technology status are reported for both contract phases, which had the following objectives: (1) establish the feasibility of Union Carbide's Silane Process for commercial application, and (2) develop an integrated process design for an Experimental Process System Development Unit (EPSDU) and a commercial facility,more » and estimate the corresponding commercial plant economic performance. To assemble the facility design, the following work was performed: (a) collection of Union Carbide's applicable background technology; (b) design, assembly, and operation of a small integrated silane-producing Process Development Unit (PDU); (c) analysis, testing, and comparison of two high-temperature methods for converting pure silane to silicon metal; and (d) determination of chemical reaction equilibria and kinetics, and vapor-liquid equilibria for chlorosilanes.« less

Factors that affect implementation of a nurse staffing directive: results from a qualitative multi-case evaluation.

PubMed

Robinson, Claire H; Annis, Ann M; Forman, Jane; Krein, Sarah L; Yankey, Nicholas; Duffy, Sonia A; Taylor, Beth; Sales, Anne E

2016-08-01

To assess implementation of the Veterans Health Administration staffing methodology directive. In 2010 the Veterans Health Administration promulgated a staffing methodology directive for inpatient nursing units to address staffing and budget forecasting. A qualitative multi-case evaluation approach assessed staffing methodology implementation. Semi-structured telephone interviews were conducted from March - June 2014 with Nurse Executives and their teams at 21 facilities. Interviews focused on the budgeting process, implementation experiences, use of data, leadership support, and training. An implementation score was created for each facility using a 4-point rating scale. The scores were used to select three facilities (low, medium and high implementation) for more detailed case studies. After analysing interview summaries, the evaluation team developed a four domain scoring structure: (1) integration of staffing methodology into budget development; (2) implementation of the Directive elements; (3) engagement of leadership and staff; and (4) use of data to support the staffing methodology process. The high implementation facility had leadership understanding and endorsement of staffing methodology, confidence in and ability to work with data, and integration of staffing methodology results into the budgeting process. The low implementation facility reported poor leadership engagement and little understanding of data sources and interpretation. Implementation varies widely across facilities. Implementing staffing methodology in facilities with complex and changing staffing needs requires substantial commitment at all organizational levels especially for facilities that have traditionally relied on historical levels to budget for staffing. Published 2016. This article is a U.S. Government work and is in the public domain in the USA.

An integrated assessment of location-dependent scaling for microalgae biofuel production facilities

DOE PAGES

Coleman, André M.; Abodeely, Jared M.; Skaggs, Richard L.; ...

2014-06-19

Successful development of a large-scale microalgae-based biofuels industry requires comprehensive analysis and understanding of the feedstock supply chain—from facility siting and design through processing and upgrading of the feedstock to a fuel product. The evolution from pilot-scale production facilities to energy-scale operations presents many multi-disciplinary challenges, including a sustainable supply of water and nutrients, operational and infrastructure logistics, and economic competitiveness with petroleum-based fuels. These challenges are partially addressed by applying the Integrated Assessment Framework (IAF) – an integrated multi-scale modeling, analysis, and data management suite – to address key issues in developing and operating an open-pond microalgae production facility.more » This is done by analyzing how variability and uncertainty over space and through time affect feedstock production rates, and determining the site-specific “optimum” facility scale to minimize capital and operational expenses. This approach explicitly and systematically assesses the interdependence of biofuel production potential, associated resource requirements, and production system design trade-offs. To provide a baseline analysis, the IAF was applied in this paper to a set of sites in the southeastern U.S. with the potential to cumulatively produce 5 billion gallons per year. Finally, the results indicate costs can be reduced by scaling downstream processing capabilities to fit site-specific growing conditions, available and economically viable resources, and specific microalgal strains.« less

Bringing the Pieces Together – Placing Core Facilities at the Core of Universities and Institutions: Lessons from Mergers, Acquisitions and Consolidations

PubMed Central

Mundoma, Claudius

2013-01-01

As organizations expand and grow, the core facilities have become more dispersed disconnected. This is happening at a time when collaborations within the organization is a driver to increased productivity. Stakeholders are looking at the best way to bring the pieces together. It is inevitable that core facilities at universities and research institutes have to be integrated in order to streamline services and facilitate ease of collaboration. The path to integration often goes through consolidation, merging and shedding of redundant services. Managing this process requires a delicate coordination of two critical factors: the human (lab managers) factor and the physical assets factor. Traditionally more emphasis has been placed on reorganizing the physical assets without paying enough attention to the professionals who have been managing the assets for years, if not decades. The presentation focuses on how a systems approach can be used to effect a smooth core facility integration process. Managing the human element requires strengthening existing channels of communication and if necessary, creating new ones throughout the organization to break cultural and structural barriers. Managing the physical assets requires a complete asset audit and this requires direct input from the administration as well as the facility managers. Organizations can harness the power of IT to create asset visibility. Successfully managing the physical assets and the human assets increases productivity and efficiency within the organization.

Yearlong semi-continuous operation of thermophilic two-stage anaerobic digesters amended with biochar for enhanced biomethane production

DOE PAGES

Shen, Yanwen; Forrester, Sara; Koval, Jason; ...

2017-05-29

This study aimed to scale up an integrated waste-to-energy system for producing pipelinequality biomethane from shake flasks experiments to two-stage digester systems with semicontinuous operation. The yearlong operation was successfully conducted to compare the performance of thermophilic anaerobic digestion (AD) of sewage sludge amended with corn stover biochar (CSBC) and pine biochar (PBC) to the control under various conditions. Both CSBC and PBC promoted the substrate utilization, methane productivity, and process stability of AD, while CSBC showed superior potential. CSBC enhanced methane content in biogas (CH 4%) and methane production rate (P CHmore » $$_4$$) by up to 25% and 37% respectively in comparison to the control, with maximum CH 4% of 95% and CH 4 yield of 0.34 L/g volatile solid (VS)-added being achieved at steady state. The biochar supplementation also led to a substantial increase of the macro- and micro-nutrients (P, K, Ca, Mg, Fe) by up to 33 times in the digestate, increasing its fertilizer value. Finally, microbial community structure and dynamics were also investigated and compared, and in particular, CSBC promoted the abundance of Clostridia and Methanosarcina. Collectively, this study proves that pyro-biochar as an effective additive material enhances AD performance with continuous operation and that CSBC shows greater potential.« less

Yearlong semi-continuous operation of thermophilic two-stage anaerobic digesters amended with biochar for enhanced biomethane production

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shen, Yanwen; Forrester, Sara; Koval, Jason

This study aimed to scale up an integrated waste-to-energy system for producing pipelinequality biomethane from shake flasks experiments to two-stage digester systems with semicontinuous operation. The yearlong operation was successfully conducted to compare the performance of thermophilic anaerobic digestion (AD) of sewage sludge amended with corn stover biochar (CSBC) and pine biochar (PBC) to the control under various conditions. Both CSBC and PBC promoted the substrate utilization, methane productivity, and process stability of AD, while CSBC showed superior potential. CSBC enhanced methane content in biogas (CH 4%) and methane production rate (P CHmore » $$_4$$) by up to 25% and 37% respectively in comparison to the control, with maximum CH 4% of 95% and CH 4 yield of 0.34 L/g volatile solid (VS)-added being achieved at steady state. The biochar supplementation also led to a substantial increase of the macro- and micro-nutrients (P, K, Ca, Mg, Fe) by up to 33 times in the digestate, increasing its fertilizer value. Finally, microbial community structure and dynamics were also investigated and compared, and in particular, CSBC promoted the abundance of Clostridia and Methanosarcina. Collectively, this study proves that pyro-biochar as an effective additive material enhances AD performance with continuous operation and that CSBC shows greater potential.« less

Massive processing of pyro-chromatogram mass spectra (py-GCMS) of soil samples using the PARAFAC2 algorithm

NASA Astrophysics Data System (ADS)

Cécillon, Lauric; Quénéa, Katell; Anquetil, Christelle; Barré, Pierre

2015-04-01

Due to its large heterogeneity at all scales (from soil core to the globe), several measurements are often mandatory to get a meaningful value of a measured soil property. A large number of measurements can therefore be needed to study a soil property whatever the scale of the study. Moreover, several soil investigation techniques produce large and complex datasets, such as pyrolysis-gas chromatography-mass spectrometry (Py-GC-MS) which produces complex 3-way data. In this context, straightforward methods designed to speed up data treatments are needed to deal with large datasets. GC-MS pyrolysis (py-GCMS) is a powerful and frequently used tool to characterize soil organic matter (SOM). However, the treatment of the results of a py-GCMS analysis of soil sample is time consuming (number of peaks, co-elution, etc.) and the treatment of large data set of py-GCMS results is rather laborious. Moreover, peak position shifts and baseline drifts between analyses make the automation of GCMS programs data treatment difficult. These problems can be fixed using the Parallel Factor Analysis 2 (PARAFAC 2, Kiers et al., 1999; Bro et al., 1999). This algorithm has been applied frequently on chromatography data but has never been applied to analyses of SOM. We developed a Matlab routine based on existing Matlab packages dedicated to the simultaneous treatment of dozens of pyro-chromatograms mass spectra. We applied this routine on 40 soil samples. The benefits and expected improvements of our method will be discussed in our poster. References Kiers et al. (1999) PARAFAC2 - PartI. A direct fitting algorithm for the PARAFAC2 model. Journal of Chemometrics, 13: 275-294. Bro et al. (1999) PARAFAC2 - PartII. Modeling chromatographic data with retention time shifts. Journal of Chemometrics, 13: 295-309.

40 CFR 430.76 - Pretreatment standards for existing sources (PSES).

Code of Federal Regulations, 2010 CFR

2010-07-01

...) EFFLUENT GUIDELINES AND STANDARDS THE PULP, PAPER, AND PAPERBOARD POINT SOURCE CATEGORY Mechanical Pulp... mechanical pulp facilities where pulp and paper at groundwood mills are produced through the application of the thermo-mechanical process; mechanical pulp facilities where the integrated production of pulp and...

Application of Framework for Integrating Safety, Security and Safeguards (3Ss) into the Design Of Used Nuclear Fuel Storage Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Badwan, Faris M.; Demuth, Scott F

Department of Energy’s Office of Nuclear Energy, Fuel Cycle Research and Development develops options to the current commercial fuel cycle management strategy to enable the safe, secure, economic, and sustainable expansion of nuclear energy while minimizing proliferation risks by conducting research and development focused on used nuclear fuel recycling and waste management to meet U.S. needs. Used nuclear fuel is currently stored onsite in either wet pools or in dry storage systems, with disposal envisioned in interim storage facility and, ultimately, in a deep-mined geologic repository. The safe management and disposition of used nuclear fuel and/or nuclear waste is amore » fundamental aspect of any nuclear fuel cycle. Integrating safety, security, and safeguards (3Ss) fully in the early stages of the design process for a new nuclear facility has the potential to effectively minimize safety, proliferation, and security risks. The 3Ss integration framework could become the new national and international norm and the standard process for designing future nuclear facilities. The purpose of this report is to develop a framework for integrating the safety, security and safeguards concept into the design of Used Nuclear Fuel Storage Facility (UNFSF). The primary focus is on integration of safeguards and security into the UNFSF based on the existing Nuclear Regulatory Commission (NRC) approach to addressing the safety/security interface (10 CFR 73.58 and Regulatory Guide 5.73) for nuclear power plants. The methodology used for adaptation of the NRC safety/security interface will be used as the basis for development of the safeguards /security interface and later will be used as the basis for development of safety and safeguards interface. Then this will complete the integration cycle of safety, security, and safeguards. The overall methodology for integration of 3Ss will be proposed, but only the integration of safeguards and security will be applied to the design of the UNFSF. The framework for integration of safeguards and security into the UNFSF will include 1) identification of applicable regulatory requirements, 2) selection of a common system that share dual safeguard and security functions, 3) development of functional design criteria and design requirements for the selected system, 4) identification and integration of the dual safeguards and security design requirements, and 5) assessment of the integration and potential benefit.« less

Prescribed Fire Education at Oklahoma State University: Training Our Future Pyros

Treesearch

John R. Weir

2008-01-01

The Rangeland Ecology and Management program at Oklahoma State University recognized the need for a practical, hands-on course designed for undergraduate and graduate students, with instruction on conducting prescribed fires for vegetation management, wildlife management, and livestock management. Two separate prescribed fire courses were initiated in the spring of...

Transcriptomic analysis reveals numerous diverse protein kinases and transcription factors involved in desiccation tolerance in the resurrection plant Myrothamnus flabellifolia

USDA-ARS?s Scientific Manuscript database

The woody resurrection plant Myrothamnus flabellifolia has remarkable tolerance to desiccation. Pyro-sequencing technology permitted us to analyze the transcriptome of M. flabellifolia during both dehydration and rehydration. We identified a total of 8287 and 8542 differentially transcribed genes du...

Fuels Combustion Research.

DTIC Science & Technology

1982-07-30

Institute, Paper 78-42 (1978). 3. Colket, M.B., Naegeli , D.W. and Glassman, I., "High Temperature Pyro- lysis of Acetaldehyde", Int’l J. of Chem...Kinetics 7. 233 (1975). 4. Aronowitz, D. and Naegeli , D.W., "High Temperature Pyrolysis of Di-methylether", Int’l J. Chem. Kinetics_ 471 (1977). • 5

Satellite Views of unprecedented smoke plume altitude and persistence after the 7 February 2009 Victoria pyrocumulonimbus storms

NASA Astrophysics Data System (ADS)

Fromm, M. D.

2009-12-01

On 7 February 2009, a date known in Australia as “Black Saturday,” the state of Victoria experienced unprecedented fire-weather conditions. Extremes of temperature, wind, and low relative humidity led to explosive fire growth and pyrocumulonimbus (pyroCb) storms that devastated property and caused many deaths. Presently it appears that the atmospheric effect of the pyroCbs might be equally extreme. Biomass burning emissions such as CO and HCN were measured in the stratosphere in unprecedented abundance for more than one month after Black Saturday. Smoke from these blowups was observed at altitudes greater than 20 km well into Austral autumn. The spread of this stratospheric pall extended from the tropics to Antarctica. Here we will show satellite observations that prove the extreme abundance and altitude of the Black Saturday plume. OMI absorbing aerosol index features were traceable for 25 days, and CALIPSO aerosol profiles showed smoke signatures in early April. ACE Imager aerosol extinction profiles reveal that Black Saturday smoke in the stratosphere was advected from its source in southeastern Australia across the Equator into the northern hemisphere.

Porous MnCo2O4 as superior anode material over MnCo2O4 nanoparticles for rechargeable lithium ion batteries

NASA Astrophysics Data System (ADS)

Baji, Dona Susan; Jadhav, Harsharaj S.; Nair, Shantikumar V.; Rai, Alok Kumar

2018-06-01

Pyro synthesis is a method to coat nanoparticles by uniform layer of carbon without using any conventional carbon source. The resultant carbon coating can be evaporated in the form of CO or CO2 at high temperature with the creation of large number of nanopores on the sample surface. Hence, a porous MnCo2O4 is successfully synthesized here with the same above strategy. It is believed that the electrolyte can easily permeate through these nanopores into the bulk of the sample and allow rapid access of Li+ ions during charge/discharge cycling. In order to compare the superiority of the porous sample synthesized by pyro synthesis method, MnCo2O4 nanoparticles are also synthesized by sol-gel synthesis method at the same parameters. When tested as anode materials for lithium ion battery application, porous MnCo2O4 electrode shows high capacity with long lifespan at all the investigated current rates in comparison to MnCo2O4 nanoparticles electrode.

Sulphur-cycling bacteria and ciliated protozoans in a Beggiatoaceae mat covering organically enriched sediments beneath a salmon farm in a southern Chilean fjord.

PubMed

Aranda, Carlos P; Valenzuela, Cristian; Matamala, Yessica; Godoy, Félix A; Aranda, Nicol

2015-11-15

The colourless mat covering organically enriched sediments underlying an intensive salmon farm in Estero Pichicolo, southern Chile, was surveyed by combined 454 PyroTag and conventional Sanger sequencing of 16S/18S ribosomal RNA genes for Bacteria and Eukarya. The mat was dominated by the sulphide-oxidizing bacteria (SOB) Candidatus Isobeggiatoa, Candidatus Parabeggiatoa and Arcobacter. By order of their abundances, sulphate-reducing bacteria (SRB) were represented by diverse deltaproteobacterial Desulfobacteraceae, but also within Desulfobulbaceae, Desulfuromonadaceae and Desulfovibrionaceae. The eukaryotic PyroTags were dominated by polychaetes, copepods and nematodes, however, ciliated protozoans were highly abundant in microscopy observations, and were represented by the genera Condylostoma, Loxophyllum and Peritromus. Finally, the abundant Sulfurimonas/Sulfurovum also suggest the occurrence of zero-valence sulphur oxidation, probably derived from Beggiatoaceae as a result of bacteriovorus infaunal activity or generated as free S(0) by the Arcobacter bacteria. The survey suggests an intense and complex sulphur cycle within the surface of salmon-farm impacted sediments. Copyright © 2015 Elsevier Ltd. All rights reserved.

Energy Systems Integration Facility Control Room | Energy Systems

Science.gov Websites

Integration Facility | NREL Energy Systems Integration Facility Control Room Energy Systems Integration Facility Control Room The Energy Systems Integration Facility control room allows system engineers as the monitoring point for the facility's integrated safety and control systems. Photo of employees

Low-cost Solar Array Project. Feasibility of the Silane Process for Producing Semiconductor-grade Silicon

NASA Technical Reports Server (NTRS)

1979-01-01

The feasibility of Union Carbide's silane process for commercial application was established. An integrated process design for an experimental process system development unit and a commercial facility were developed. The corresponding commercial plant economic performance was then estimated.

Evaluation of Mercury in Liquid Waste Processing Facilities - Phase I Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jain, V.; Occhipinti, J.; Shah, H.

2015-07-01

This report provides a summary of Phase I activities conducted to support an Integrated Evaluation of Mercury in Liquid Waste System (LWS) Processing Facilities. Phase I activities included a review and assessment of the liquid waste inventory and chemical processing behavior of mercury using a system by system review methodology approach. Gaps in understanding mercury behavior as well as action items from the structured reviews are being tracked. 64% of the gaps and actions have been resolved.

Evaluation of mercury in liquid waste processing facilities - Phase I report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jain, V.; Occhipinti, J. E.; Shah, H.

2015-07-01

This report provides a summary of Phase I activities conducted to support an Integrated Evaluation of Mercury in Liquid Waste System (LWS) Processing Facilities. Phase I activities included a review and assessment of the liquid waste inventory and chemical processing behavior of mercury using a system by system review methodology approach. Gaps in understanding mercury behavior as well as action items from the structured reviews are being tracked. 64% of the gaps and actions have been resolved.

Commercial-scale demonstration of the Liquid Phase Methanol (LPMEOH{trademark}) process. Technical progress report number 6, October 1--December 31, 1995

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-12-31

The project involves the construction of an 80,000 gallons per day (260 TPD) methanol unit utilizing coal-derived synthesis gas from Eastman`s integrated coal gasification facility. The new equipment consists of synthesis gas feed preparation and compression facilities, the liquid phase reactor and auxiliaries, product distillation facilities, and utilities. The technology to be demonstrated is the product of a cooperative development effort by Air Products and DOE in a program that started in 1981. Developed to enhance electric power generation using integrated gasification combined cycle (IGCC) technology, the LPMEOH{trademark} process is ideally suited for directly processing gases produced by modern-day coalmore » gasifiers. This liquid phase process suspends fine catalyst particles in an inert liquid, forming a slurry. The slurry dissipates the heat of the chemical reaction away from the catalyst surface protecting the catalyst and allowing the methanol synthesis reaction to proceed at higher rates. At the Eastman complex, the technology will be integrated with existing coal-gasifiers. A carefully developed test plan will allow operations at Eastman to simulate electricity demand load-following in coal-based IGCC facilities. The operations will also demonstrate the enhanced stability and heat dissipation of the conversion process, its reliable on/off operation, and its ability to produce methanol as a clean liquid fuel without additional upgrading. An off-site product testing program will be conducted to demonstrate the suitability of the methanol product as a transportation fuel and as a fuel for stationary applications for small modular electric power generators for distributed power.« less

Sapphire Energy - Integrated Algal Biorefinery

DOE Office of Scientific and Technical Information (OSTI.GOV)

White, Rebecca L.; Tyler, Mike

2015-07-22

Sapphire Energy, Inc. (SEI) is a leader in large-scale photosynthetic algal biomass production, with a strongly cohesive research, development, and operations program. SEI takes a multidiscipline approach to integrate lab-based strain selection, cultivation and harvest and production scale, and extraction for the production of Green Crude oil, a drop in replacement for traditional crude oil.. SEI’s technical accomplishments since 2007 have produced a multifunctional platform that can address needs for fuel, feed, and other higher value products. Figure 1 outlines SEI’s commercialization process, including Green Crude production and refinement to drop in fuel replacements. The large scale algal biomass productionmore » facility, the SEI Integrated Algal Biorefinery (IABR), was built in Luna County near Columbus, New Mexico (see fig 2). The extraction unit was located at the existing SEI facility in Las Cruces, New Mexico, approximately 95 miles from the IABR. The IABR facility was constructed on time and on budget, and the extraction unit expansion to accommodate the biomass output from the IABR was completed in October 2012. The IABR facility uses open pond cultivation with a proprietary harvesting method to produce algal biomass; this biomass is then shipped to the extraction facility for conversion to Green Crude. The operation of the IABR and the extraction facilities has demonstrated the critical integration of traditional agricultural techniques with algae cultivation knowledge for algal biomass production, and the successful conversion of the biomass to Green Crude. All primary unit operations are de-risked, and at a scale suitable for process demonstration. The results are stable, reliable, and long-term cultivation of strains for year round algal biomass production. From June 2012 to November 2014, the IABR and extraction facilities produced 524 metric tons (MT) of biomass (on a dry weight basis), and 2,587 gallons of Green Crude. Additionally, the IABR demonstrated significant year over year yield improvements (2013 to 2014), and reduction in the cost of biomass production. Therefore, the IABR fulfills a number of critical functions in SEI’s integrated development pipeline. These functions are critical in general for the commercialization of algal biomass production and production of biofuels from algal biomass.« less

Integrating Sustainability Programs into the Facilities Capital Planning Process

ERIC Educational Resources Information Center

Buchanan, Susan

2011-01-01

With detailed information about the costs and benefits of potential green investments, educational facilities can effectively evaluate which initiatives will ultimately provide the greatest results over the short and long term. Based on its overall goals, every school, college, or university will have different values and therefore different…

Further Research on the Electrification of Pyrocumulus Clouds

NASA Technical Reports Server (NTRS)

Lang, Timothy J.; Laroche, Kendell; Baum, Bryan; Bateman, Monte; Mach, Douglas

2015-01-01

Past research on pyrocumulus electrification has demonstrated that a variety of lightning types can occur, including cloud-to-ground (CG) flashes, sometimes of dominant positive polarity, as well as small intra-cloud (IC) discharges in the upper levels of the pyro-cloud. In Colorado during summer 2012, the first combined polarimetric radar, multi-Doppler radar, and three-dimensional lightning mapping array (LMA) observations of lightning-producing pyrocumulus were obtained. These observations suggested that the National Lightning Detection Network (NLDN) was not sensitive enough to detect the small IC flashes that appear to be the dominant mode of lightning in these clouds. However, after an upgrade to the network in late 2012, the NLDN began detecting some of this pyrocumulus lightning. Multiple pyrocumulus clouds documented by the University of Wisconsin for various fires in 2013 and 2014 (including over the Rim, West Fork Complex, Yarnell Hill, Hardluck, and several other incidents) are examined and reported on here. This study exploits the increased-sensitivity NLDN as well as the new nationwide U.S. network of polarimetric Next-generation Radars (NEXRADs). These observations document the common occurrence of a polarimetric "dirty ice" signature - modest reflectivities (20-40+ dBZ), near-zero differential reflectivity, and reduced correlation coefficient (less than 0.9) - prior to the production of lightning. This signature is indicative of a mixture of ash and ice particles in the upper levels of the pyro-cloud (less than -20 C), with the ice interpreted as being necessary for pyro-cloud electrification. Pseudo-Geostationary Lightning Mapper (GLM) data will be produced from the 2012 LMA observations, and the ability of GLM to detect small pyrocumulus ICs will be assessed. The utility of lightning and polarimetric radar for documenting rapid wildfire growth, as well as for documenting pyrocumulus impacts on the composition of the upper troposphere/lower stratosphere (UTLS), will be discussed.

Interpretation of Aura satellite observations of CO and aerosol index related to the December 2006 Australia fires

NASA Astrophysics Data System (ADS)

Luo, M.; Boxe, C.; Jiang, J.; Nassar, R.; Livesey, N.

2009-11-01

Enhanced Carbon Monoxide (CO) in the upper troposphere (UT) is shown by collocated Tropospheric Emission Spectrometer (TES) and Microwave Limb Sounder (MLS) measurements near and down-wind from the known wildfire region of SE Australia from 12-19 December 2006. Enhanced UV aerosol index (AI) derived from Ozone Monitoring Instrument (OMI) measurements correlate with these high CO concentrations. HYSPLIT model back trajectories trace selected air parcels to the SE Australia fire region as their initial location, where TES observes enhanced CO in the upper and lower troposphere. Simultaneously, they show a lack of vertical advection along their tracks. TES retrieved CO vertical profiles in the higher and lower southern latitudes are examined together with the averaging kernels and show that TES CO retrievals are most sensitive at approximately 300-400 hPa. The enhanced CO observed by TES at the upper (215 hPa) and lower (681 hPa) troposphere are, therefore, influenced by mid-tropospheric CO. GEOS-Chem model simulations with an 8-day emission inventory, as the wildfire source over Australia, are sampled to the TES/MLS observation times and locations. These simulations only show CO enhancements in the lower troposphere near and down-wind from the wildfire region of SE Australia with drastic underestimates of UT CO. Although CloudSat along-track ice-water content curtains are examined to see whether possible vertical convection events can explain the high UT CO values, sparse observations of collocated Aura CO and CloudSat along-track ice-water content measurements for the single event precludes any conclusive correlation. Vertical convection that uplift fire-induced CO (i.e. most notably referred to as pyro-cumulonimbus, pyroCb) may provide an explanation for the incongruence between these simulations and the TES/MLS observations of enhanced CO in the UT. Future GEOS-Chem simulations are needed to validate this conjecture as the the PyroCb mechanism is currently not incorporated in GEOS-Chem.

New Applications of the Human Whole Blood Pyrogen Assay (PyroCheck).

PubMed

Fennrich; Wendel; Hartung

1999-01-01

The absence of pyrogens in injectable drugs is an indispensable safety control because contaminants causing fever pose a life-threatening risk to the patient resulting in the worst case in death by shock. When fever- inducing agents, i.e.pyrogens, come into contact with the immunocompetent cells in blood, these cells release mediators which transmit the fever signal to the thermoregulatory centre of the brain. The Phamocopoeia lists currently two test systems for pyrogenicity: 1. The in vivo rabbit pyrogen test which measures the fever reaction following injection of the sample to the animals. 2. The in vitro Limulus Amebocyte Lysate assay (LAL) which measures the coagulation in a lysate prepared from the blood of the horseshoe crab specifically initiated by endotoxins, i.e. cell wall components from Gram-negative bacteria. The new test presented here (PyroCheck) exploits the reaction of monocytes/macrophages for the detection of pyrogens: human whole blood taken from healthy volunteers is incubated in the presence of the test sample in any form, be it a solution, a powder or even solid material. Pyrogenic contaminations initiate the release of the "endogenous pyrogen" Interleukin-1beta determined by ELISA after a fixed incubation time. The technology presently listed in the Pharmacopoeia is limited to parenteralia (rabbit test: biologicals and pharmaceuticals, LAL: predominantly pharmaceuticals). In the EU Medical Devices Directive from 1995 the rabbit pyrogen test for medical products is in some cases requested. (in some cases LAL of an eluate from the device). However, pyrogen-testing needs to cover also innovative high-tech products such as medical devices (implants, medical plastic materials, dialysis machines), cellular therapies and species-specific agents (e.g. recombinant proteins). Here we report that the human blood test PyroCheck is suitable for testing filters in air quality control as well as for assessing medical devices and biocompatibility (dialysate fluid), i.e. that it can be extended to a wide spectrum of applications.

Relationships between school support, school facilities, ICT culture and mathematics teachers' attitudes towards ICT in teaching and learning

NASA Astrophysics Data System (ADS)

Ayub, Ahmad Fauzi Mohd; Bakar, Kamariah Abu; Ismail, Rohayati

2012-05-01

Information communication Technology (ICT) has been a major influence in the Malaysian Education System, especially in the teaching of mathematics. Since 2003, the Malaysian Ministry of Education has provided incentives to mathematics teacher to motivate them to use ICT using English as the medium of instruction, during the teaching and learning process. However, there are barriers that prevented mathematics teachers from using ICT in the classrooms. This study is to determine factors that influenced the attitudes of Malaysian Mathematic Teachers in integrating ICT in their teaching and learning. One hundred ninety one mathematics teachers were randomly selected for the purpose of this study. The three factors investigated were school support, school facilities and school culture which had been selected to be correlated with teachers' attitudes towards integrating ICT in the teaching and learning of mathematics. Findings showed that significant positive relationships existed between teachers' attitudes toward integrating ICT in the teaching and learning and school support, school facilities and ICT culture and This finding indicated that, in order to develop teachers' attitudes in using ICT during their teaching and learning process, they needed support from the school principals and also their colleagues. Apart from that, school facilities and also ICT culture were also found to be essential.

System integration of marketable subsystems. [for residential solar heating and cooling

NASA Technical Reports Server (NTRS)

1979-01-01

Progress is reported in the following areas: systems integration of marketable subsystems; development, design, and building of site data acquisition subsystems; development and operation of the central data processing system; operation of the MSFC Solar Test Facility; and systems analysis.

Analysis of weather condition influencing fire regime in Italy

NASA Astrophysics Data System (ADS)

Bacciu, Valentina; Masala, Francesco; Salis, Michele; Sirca, Costantino; Spano, Donatella

2014-05-01

Fires have a crucial role within Mediterranean ecosystems, with both negative and positive impacts on all biosphere components and with reverberations on different scales. Fire determines the landscape structure and plant composition, but it is also the cause of enormous economic and ecological damages, beside the loss of human life. In addition, several authors are in agreement suggesting that, during the past decades, changes on fire patterns have occurred, especially in terms of fire-prone areas expansion and fire season lengthening. Climate and weather are two of the main controlling agents, directly and indirectly, of fire regime influencing vegetation productivity, causing water stress, igniting fires through lightning, or modulating fire behavior through wind. On the other hand, these relationships could be not warranted in areas where most ignitions are caused by people (Moreno et al. 2009). Specific analyses of the driving forces of fire regime across countries and scales are thus still required in order to better anticipate fire seasons and also to advance our knowledge of future fire regimes. The objective of this work was to improve our knowledge of the relative effects of several weather variables on forest fires in Italy for the period 1985-2008. Meteorological data were obtained through the MARS (Monitoring Agricultural Resources) database, interpolated at 25x25 km scale. Fire data were provided by the JRC (Join Research Center) and the CFVA (Corpo Forestale e di Vigilanza Ambientale, Sardinia). A hierarchical cluster analysis, based on fire and weather data, allowed the identification of six homogeneous areas in terms of fire occurrence and climate (pyro-climatic areas). Two statistical techniques (linear and non-parametric models) were applied in order to assess if inter-annual variability in weather pattern and fire events had a significant trend. Then, through correlation analysis and multi-linear regression modeling, we investigated the influence of weather variables on fire activity across a range of time- and spatial-scales. The analysis revealed a general decrease of both number of fires and burned area, although not everywhere with the same magnitude. Overall, regression models where highly significant (p<0.001), and the explained variance ranged from 36% to 80% for fire number and from 37% to 76% for burned area, depending on pyro-climatic area. Moreover, our results contributed in determining the relative importance of climate variables acting at different timescales as control on intrinsic (i.e. flammability and moisture) and extrinsic (i.e. fuel amount and structure) characteristics of vegetation, thus strongly influencing fire occurrence. The good performance of our models, especially in the most fire affected pyro-climatic areas of Italy, and the better understanding of the main driver of fire variability gained through this work could be of great help for fire management among the different pyro-climatic areas.

Energy System Integration Facility Secure Data Center | Energy Systems

Science.gov Websites

Integration Facility | NREL Energy System Integration Facility Secure Data Center Energy System Integration Facility Secure Data Center The Energy Systems Integration Facility's Secure Data Center provides

Integrated Facilities and Infrastructure Plan.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Reisz Westlund, Jennifer Jill

Our facilities and infrastructure are a key element of our capability-based science and engineering foundation. The focus of the Integrated Facilities and Infrastructure Plan is the development and implementation of a comprehensive plan to sustain the capabilities necessary to meet national research, design, and fabrication needs for Sandia National Laboratories’ (Sandia’s) comprehensive national security missions both now and into the future. A number of Sandia’s facilities have reached the end of their useful lives and many others are not suitable for today’s mission needs. Due to the continued aging and surge in utilization of Sandia’s facilities, deferred maintenance has continuedmore » to increase. As part of our planning focus, Sandia is committed to halting the growth of deferred maintenance across its sites through demolition, replacement, and dedicated funding to reduce the backlog of maintenance needs. Sandia will become more agile in adapting existing space and changing how space is utilized in response to the changing requirements. This Integrated Facilities & Infrastructure (F&I) Plan supports the Sandia Strategic Plan’s strategic objectives, specifically Strategic Objective 2: Strengthen our Laboratories’ foundation to maximize mission impact, and Strategic Objective 3: Advance an exceptional work environment that enables and inspires our people in service to our nation. The Integrated F&I Plan is developed through a planning process model to understand the F&I needs, analyze solution options, plan the actions and funding, and then execute projects.« less

Energy Systems Integration Facility Videos | Energy Systems Integration

Science.gov Websites

Facility | NREL Energy Systems Integration Facility Videos Energy Systems Integration Facility Integration Facility NREL + SolarCity: Maximizing Solar Power on Electrical Grids Redefining What's Possible for Renewable Energy: Grid Integration Robot-Powered Reliability Testing at NREL's ESIF Microgrid

DKIST facility management system integration

NASA Astrophysics Data System (ADS)

White, Charles R.; Phelps, LeEllen

2016-07-01

The Daniel K. Inouye Solar Telescope (DKIST) Observatory is under construction at Haleakalā, Maui, Hawai'i. When complete, the DKIST will be the largest solar telescope in the world. The Facility Management System (FMS) is a subsystem of the high-level Facility Control System (FCS) and directly controls the Facility Thermal System (FTS). The FMS receives operational mode information from the FCS while making process data available to the FCS and includes hardware and software to integrate and control all aspects of the FTS including the Carousel Cooling System, the Telescope Chamber Environmental Control Systems, and the Temperature Monitoring System. In addition it will integrate the Power Energy Management System and several service systems such as heating, ventilation, and air conditioning (HVAC), the Domestic Water Distribution System, and the Vacuum System. All of these subsystems must operate in coordination to provide the best possible observing conditions and overall building management. Further, the FMS must actively react to varying weather conditions and observational requirements. The physical impact of the facility must not interfere with neighboring installations while operating in a very environmentally and culturally sensitive area. The FMS system will be comprised of five Programmable Automation Controllers (PACs). We present a pre-build overview of the functional plan to integrate all of the FMS subsystems.

Commercial-scale biotherapeutics manufacturing facility for plant-made pharmaceuticals.

PubMed

Holtz, Barry R; Berquist, Brian R; Bennett, Lindsay D; Kommineni, Vally J M; Munigunti, Ranjith K; White, Earl L; Wilkerson, Don C; Wong, Kah-Yat I; Ly, Lan H; Marcel, Sylvain

2015-10-01

Rapid, large-scale manufacture of medical countermeasures can be uniquely met by the plant-made-pharmaceutical platform technology. As a participant in the Defense Advanced Research Projects Agency (DARPA) Blue Angel project, the Caliber Biotherapeutics facility was designed, constructed, commissioned and released a therapeutic target (H1N1 influenza subunit vaccine) in <18 months from groundbreaking. As of 2015, this facility was one of the world's largest plant-based manufacturing facilities, with the capacity to process over 3500 kg of plant biomass per week in an automated multilevel growing environment using proprietary LED lighting. The facility can commission additional plant grow rooms that are already built to double this capacity. In addition to the commercial-scale manufacturing facility, a pilot production facility was designed based on the large-scale manufacturing specifications as a way to integrate product development and technology transfer. The primary research, development and manufacturing system employs vacuum-infiltrated Nicotiana benthamiana plants grown in a fully contained, hydroponic system for transient expression of recombinant proteins. This expression platform has been linked to a downstream process system, analytical characterization, and assessment of biological activity. This integrated approach has demonstrated rapid, high-quality production of therapeutic monoclonal antibody targets, including a panel of rituximab biosimilar/biobetter molecules and antiviral antibodies against influenza and dengue fever. © 2015 Society for Experimental Biology, Association of Applied Biologists and John Wiley & Sons Ltd.

SCI Hazard Report Methodology

NASA Technical Reports Server (NTRS)

Mitchell, Michael S.

2010-01-01

This slide presentation reviews the methodology in creating a Source Control Item (SCI) Hazard Report (HR). The SCI HR provides a system safety risk assessment for the following Ares I Upper Stage Production Contract (USPC) components (1) Pyro Separation Systems (2) Main Propulsion System (3) Reaction and Roll Control Systems (4) Thrust Vector Control System and (5) Ullage Settling Motor System components.

An exergy based assessment of the production and conversion of switchgrass, equine waste and forest residue to bio-oil using fast pyrolysis

USDA-ARS?s Scientific Manuscript database

The resource efficiency of biofuel production via biomass pyrolysis is evaluated using exergy as an assessment metric. Three feedstocks, important to various sectors of US agriculture, switchgrass, forest residue and equine waste are considered for conversion to bio-oil (pyrolysis oil) via fast pyro...

Cryogenic Caging for Science Instrumentation

NASA Technical Reports Server (NTRS)

Penanen, Konstantin; Chui, Talso C.

2011-01-01

A method has been developed for caging science instrumentation to protect from pyro-shock and EDL (entry, descent, and landing) acceleration damage. Caging can be achieved by immersing the instrument (or its critical parts) in a liquid and solidifying the liquid by cooling. After the launch shock and/or after the payload has landed, the solid is heated up and evaporated.

Integration Test of the High Voltage Hall Accelerator System Components

NASA Technical Reports Server (NTRS)

Kamhawi, Hani; Haag, Thomas; Huang, Wensheng; Pinero, Luis; Peterson, Todd; Dankanich, John

2013-01-01

NASA Glenn Research Center is developing a 4 kilowatt-class Hall propulsion system for implementation in NASA science missions. NASA science mission performance analysis was completed using the latest high voltage Hall accelerator (HiVHAc) and Aerojet-Rocketdyne's state-of-the-art BPT-4000 Hall thruster performance curves. Mission analysis results indicated that the HiVHAc thruster out performs the BPT-4000 thruster for all but one of the missions studied. Tests of the HiVHAc system major components were performed. Performance evaluation of the HiVHAc thruster at NASA Glenn's vacuum facility 5 indicated that thruster performance was lower than performance levels attained during tests in vacuum facility 12 due to the lower background pressures attained during vacuum facility 5 tests when compared to vacuum facility 12. Voltage-Current characterization of the HiVHAc thruster in vacuum facility 5 showed that the HiVHAc thruster can operate stably for a wide range of anode flow rates for discharge voltages between 250 and 600 volts. A Colorado Power Electronics enhanced brassboard power processing unit was tested in vacuum for 1,500 hours and the unit demonstrated discharge module efficiency of 96.3% at 3.9 kilowatts and 650 volts. Stand-alone open and closed loop tests of a VACCO TRL 6 xenon flow control module were also performed. An integrated test of the HiVHAc thruster, brassboard power processing unit, and xenon flow control module was performed and confirmed that integrated operation of the HiVHAc system major components. Future plans include continuing the maturation of the HiVHAc system major components and the performance of a single-string integration test.

Light Microscopy Module Imaging Tested and Demonstrated

NASA Technical Reports Server (NTRS)

Gati, Frank

2004-01-01

The Fluids Integrated Rack (FIR), a facility-class payload, and the Light Microscopy Module (LMM), a subrack payload, are integrated research facilities that will fly in the U.S. Laboratory module, Destiny, aboard the International Space Station. Both facilities are being engineered, designed, and developed at the NASA Glenn Research Center by Northrop Grumman Information Technology. The FIR is a modular, multiuser scientific research facility that is one of two racks that make up the Fluids and Combustion Facility (the other being the Combustion Integrated Rack). The FIR has a large volume dedicated for experimental hardware; easily reconfigurable diagnostics, power, and data systems that allow for unique experiment configurations; and customizable software. The FIR will also provide imagers, light sources, power management and control, command and data handling for facility and experiment hardware, and data processing and storage. The first payload in the FIR will be the LMM. The LMM integrated with the FIR is a remotely controllable, automated, on-orbit microscope subrack facility, with key diagnostic capabilities for meeting science requirements--including video microscopy to observe microscopic phenonema and dynamic interactions, interferometry to make thin-film measurements with nanometer resolution, laser tweezers to manipulate micrometer-sized particles, confocal microscopy to provide enhanced three-dimensional visualization of structures, and spectrophotometry to measure the photonic properties of materials. Vibration disturbances were identified early in the LMM development phase as a high risk for contaminating the science microgravity environment. An integrated FIR-LMM test was conducted in Glenn's Acoustics Test Laboratory to assess mechanical sources of vibration and their impact to microscopic imaging. The primary purpose of the test was to characterize the LMM response at the sample location, the x-y stage within the microscope, to vibration emissions from the FIR and LMM support structures.

40 CFR 430.74 - Effluent limitations representing the degree of effluent reduction attainable by the application...

Code of Federal Regulations, 2011 CFR

2011-07-01

...) EFFLUENT GUIDELINES AND STANDARDS THE PULP, PAPER, AND PAPERBOARD POINT SOURCE CATEGORY Mechanical Pulp... mechanical pulp facilities where pulp and paper at groundwood mills are produced through the application of the thermo-mechanical process; mechanical pulp facilities where the integrated production of pulp and...

40 CFR 430.74 - Effluent limitations representing the degree of effluent reduction attainable by the application...

Code of Federal Regulations, 2010 CFR

2010-07-01

...) EFFLUENT GUIDELINES AND STANDARDS THE PULP, PAPER, AND PAPERBOARD POINT SOURCE CATEGORY Mechanical Pulp... mechanical pulp facilities where pulp and paper at groundwood mills are produced through the application of the thermo-mechanical process; mechanical pulp facilities where the integrated production of pulp and...

Earth integrated design: office dormitory facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shapira, H. B.; Barnes, P. R.

1980-01-01

The generation process of the design of the Joint Institute for Heavy Ion Research is described. Architectural and energy considerations are discussed. The facility will contain living quarters for guest scientists who come to Oak Ridge to conduct short experiments and sleeping alcoves for local researchers on long experimental shifts as well as office space. (MHR)

Development of the CLAES instrument aperture door system

NASA Technical Reports Server (NTRS)

Stubbs, D. M.

1990-01-01

The design, assembly, and test processes followed in developing a space-qualified aperture door system are described. A blackbody calibration source is mounted inside the door, requiring the assembly to open and close a minimum of 150 cycles for instrument recalibration. Within the door system are four separate mechanisms, three of which are redundant; a pyro launch latch, a hinge bearing assembly, and a pair of pivot mechanisms. Decoupling devices within the pivot mechanisms allow an active drive unit to automatically overdrive a failed drive unit. The door is also stowable for possible Shuttle retrieval and re-entry. Illustrations and photographs of the flight hardware help acquaint the reader with the design. The aim is to pass on lessons learned in all phases of developing this spaceflight mechanism.

Commercial-scale demonstration of the Liquid Phase Methanol (LPMEOH{trademark}) process. Technical progress report number 9, July 1--September 30, 1996

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

The Liquid Phase Methanol (LPMEOH{trademark}) Demonstration Project at Kingsport, Tennessee, is a $213.7 million cooperative agreement between the US Department of Energy (DOE) and Air Products Liquid Phase Conversion Company, L.P. (the Partnership). The LPMEOH{trademark} Process Demonstration Unit is being built at a site located at the Eastman Chemical Company (Eastman) complex in Kingsport. The project involves the construction of an 80,000 gallons per day (260 tons per day (TPD)) methanol unit utilizing coal-derived synthesis gas from Eastman`s integrated coal gasification facility. The new equipment consists of synthesis gas feed preparation and compression facilities, the liquid phase reactor and auxiliaries,more » product distillation facilities, and utilities. This liquid phase process suspends fine catalyst particles in an inert liquid, forming a slurry. The slurry dissipates the heat of the chemical reaction away from the catalyst surface, protecting the catalyst and allowing the methanol synthesis reaction to proceed at higher rates. At the Eastman complex, the technology is being integrated with existing coal-gasifiers.« less

KSC-20171002-MH-CSH01_0001-MISSE_Arrival_Integration_H265-3170951

NASA Image and Video Library

2017-10-02

The Materials International Space Station Experiment-Flight Facility, or MISSE-FF, hardware arrived at the Space Station Processing Facility low bay at NASA's Kennedy Space Center in Florida. MISSE is unpacked and moved for integration and processing. MISSE will be used to test various materials and computing elements on the exterior of the space station. They will be exposed to the harsh environment of low-Earth orbit, including to a vacuum, atomic oxygen, ultraviolet radiation, direct sunlight and extreme heat and cold. The experiment will provide a better understanding of material durability, from coatings to electronic sensors, which could be applied to future spacecraft designs. MISSE will be delivered to the space station on a future commercial resupply mission.

Integration of design and inspection

NASA Astrophysics Data System (ADS)

Simmonds, William H.

1990-08-01

Developments in advanced computer integrated manufacturing technology, coupled with the emphasis on Total Quality Management, are exposing needs for new techniques to integrate all functions from design through to support of the delivered product. One critical functional area that must be integrated into design is that embracing the measurement, inspection and test activities necessary for validation of the delivered product. This area is being tackled by a collaborative project supported by the UK Government Department of Trade and Industry. The project is aimed at developing techniques for analysing validation needs and for planning validation methods. Within the project an experimental Computer Aided Validation Expert system (CAVE) is being constructed. This operates with a generalised model of the validation process and helps with all design stages: specification of product requirements; analysis of the assurance provided by a proposed design and method of manufacture; development of the inspection and test strategy; and analysis of feedback data. The kernel of the system is a knowledge base containing knowledge of the manufacturing process capabilities and of the available inspection and test facilities. The CAVE system is being integrated into a real life advanced computer integrated manufacturing facility for demonstration and evaluation.

STS-82 Discovery payloads being integrated in VPF

NASA Image and Video Library

1997-01-30

KENNEDY SPACE CENTER, FLORIDA STS-82 PREPARATIONS VIEW --- Workers in the Kennedy Space Center (KSC) Vertical Processing Facility (VPF) prepare to integrate the Small Orbital Replacement Unit (Oru) Protective Enclosure (Sope), shown here being lifted, with the ORU Carrier shelf, in background, as part of the pre-launch processing for STS-82. The mission, the second one devoted to servicing of the HST, is targeted for launch on February 11, 1997.

A Specific Long-Term Plan for Management of U.S. Nuclear Spent Fuel

DOE Office of Scientific and Technical Information (OSTI.GOV)

Levy, Salomon

2006-07-01

A specific plan consisting of six different steps is proposed to accelerate and improve the long-term management of U.S. Light Water Reactor (LWR) spent nuclear fuel. The first step is to construct additional, centralized, engineered (dry cask) spent fuel facilities to have a backup solution to Yucca Mountain (YM) delays or lack of capacity. The second step is to restart the development of the Integral Fast Reactor (IFR), in a burner mode, because of its inherent safety characteristics and its extensive past development in contrast to Acceleration Driven Systems (ADS). The IFR and an improved non-proliferation version of its pyro-processingmore » technology can burn the plutonium (Pu) and minor actinides (MA) obtained by reprocessing LWR spent fuel. The remaining IFR and LWR fission products will be treated for storage at YM. The radiotoxicity of that high level waste (HLW) will fall below that of natural uranium in less than one thousand years. Due to anticipated increased capital, maintenance, and research costs for IFR, the third step is to reduce the required number of IFRs and their potential delays by implementing multiple recycles of Pu and Neptunium (Np) MA in LWR. That strategy is to use an advanced separation process, UREX+, and the MIX Pu option where the role and degradation of Pu is limited by uranium enrichment. UREX+ will decrease proliferation risks by avoiding Pu separation while the MIX fuel will lead to an equilibrium fuel recycle mode in LWR which will reduce U. S. Pu inventory and deliver much smaller volumes of less radioactive HLW to YM. In both steps two and three, Research and Development (R and D) is to emphasize the demonstration of multiple fuel reprocessing and fabrication, while improving HLW treatment, increasing proliferation resistance, and reducing losses of fissile material. The fourth step is to license and construct YM because it is needed for the disposal of defense wastes and the HLW to be generated under the proposed plan. The fifth step consists of developing a risk informed methodology to assess the various options available for disposition of LWR spent fuel and to select among them. The sixth step is to modify the current U. S. infrastructure and to create a climate to increase the utilization of uranium and the sustainability of nuclear generated electricity. (author)« less

Reengineering the JPL Spacecraft Design Process

NASA Technical Reports Server (NTRS)

Briggs, C.

1995-01-01

This presentation describes the factors that have emerged in the evolved process of reengineering the unmanned spacecraft design process at the Jet Propulsion Laboratory in Pasadena, California. Topics discussed include: New facilities, new design factors, new system-level tools, complex performance objectives, changing behaviors, design integration, leadership styles, and optimization.

Educational Facility Design and Project Based Learning: "The Real Connection"

ERIC Educational Resources Information Center

Schrader, David L.; Sole, John

2009-01-01

There is a case to be made for the integration of the Project Based Service Learning (PBSL) process and the design and construction of educational facilities. A growing body of research supports the notion that the formulaic educational system of the last hundred years may no longer serve the learning styles of new and future generations. Their…

Inhibition of Clostridium perfringens spore germination and outgrowth by lemon juice and vinegar product in reduced NaCl roast beef

USDA-ARS?s Scientific Manuscript database

Inhibition of Clostridium perfringens spore germination and outgrowth in reduced sodium roast beef by a blend of buffered lemon juice concentrate and vinegar (MoStatin LV) during abusive exponential cooling was evaluated. Roast beef containing salt (NaCl; 1, 1.5, or 2%, wt/wt), blend of sodium pyro-...

Transient absorption spectroscopy of a monofullerene C60-bis-(pyropheophorbide a) molecular system in polar and nonpolar environments

NASA Astrophysics Data System (ADS)

Al Omari, S.; Ermilov, E. A.; Helmreich, M.; Jux, N.; Hirsch, A.; Röder, B.

2004-09-01

The population dynamics of the excited and ground states of the monofullerene-bis (pyropheophorbide a) complex (FP1) were studied in polar (DMF) and nonpolar (toluene) solvents using picosecond transient absorption techniques. A strong quenching of the fluorescence signal of FP1 was observed in both solvents, in comparison to the fluorescence of bis (pyropheophorbide a) (P2). This quenching is due to an intramolecular photoinduced electron transfer from the pyropheophorbide a (pyroPheo) moiety to the fullerene C60 monoadduct. In DMF the charge-separated (CS) state of FP1 has a lifetime of 0.32 ns and undergoes a direct transition to the ground state, resulting in a very low value of photosensitised singlet oxygen generation. In toluene, energy transfer from the first excited triplet state of pyroPheo, which has been populated via relaxation of the CS state, generates a considerable amount of singlet oxygen. The lifetime of the CS state in the nonpolar solvent was estimated to be 0.29 ns. It was also shown that in both DMF and toluene the first excited singlet state as well as the triplet state of the fullerene moiety in FP1 are not occupied.

The home hemodialysis hub: physical infrastructure and integrated governance structure.

PubMed

Marshall, Mark R; Young, Bessie A; Fox, Sally J; Cleland, Calli J; Walker, Robert J; Masakane, Ikuto; Herold, Aaron M

2015-04-01

An effective home hemodialysis program critically depends on adequate hub facilities and support functions and on transparent and accountable organizational processes. The likelihood of optimal service delivery and patient care will be enhanced by fit-for-purpose facilities and implementation of a well-considered governance structure. In this article, we describe the required accommodation and infrastructure for a home hemodialysis program and a generic organizational structure that will support both patient-facing clinical activities and business processes. © 2015 International Society for Hemodialysis.

Enterprise SRS: leveraging ongoing operations to advance nuclear fuel cycles research and development programs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Murray, A.M.; Marra, J.E.; Wilmarth, W.R.

2013-07-01

The Savannah River Site (SRS) is re-purposing its vast array of assets (including H Canyon - a nuclear chemical separation plant) to solve issues regarding advanced nuclear fuel cycle technologies, nuclear materials processing, packaging, storage and disposition. The vehicle for this transformation is Enterprise SRS which presents a new, radical view of SRS as a united endeavor for 'all things nuclear' as opposed to a group of distinct and separate entities with individual missions and organizations. Key among the Enterprise SRS strategic initiatives is the integration of research into SRS facilities but also in other facilities in conjunction with on-goingmore » missions to provide researchers from other national laboratories, academic institutions, and commercial entities the opportunity to demonstrate their technologies in a relevant environment and scale prior to deployment. To manage that integration of research demonstrations into site facilities, a center for applied nuclear materials processing and engineering research has been established in SRS.« less

Modernization of B-2 Data, Video, and Control Systems Infrastructure

NASA Technical Reports Server (NTRS)

Cmar, Mark D.; Maloney, Christian T.; Butala, Vishal D.

2012-01-01

The National Aeronautics and Space Administration (NASA) Glenn Research Center (GRC) Plum Brook Station (PBS) Spacecraft Propulsion Research Facility, commonly referred to as B-2, is NASA s third largest thermal-vacuum facility with propellant systems capability. B-2 has completed a modernization effort of its facility legacy data, video and control systems infrastructure to accommodate modern integrated testing and Information Technology (IT) Security requirements. Integrated systems tests have been conducted to demonstrate the new data, video and control systems functionality and capability. Discrete analog signal conditioners have been replaced by new programmable, signal processing hardware that is integrated with the data system. This integration supports automated calibration and verification of the analog subsystem. Modern measurement systems analysis (MSA) tools are being developed to help verify system health and measurement integrity. Legacy hard wired digital data systems have been replaced by distributed Fibre Channel (FC) network connected digitizers where high speed sampling rates have increased to 256,000 samples per second. Several analog video cameras have been replaced by digital image and storage systems. Hard-wired analog control systems have been replaced by Programmable Logic Controllers (PLC), fiber optic networks (FON) infrastructure and human machine interface (HMI) operator screens. New modern IT Security procedures and schemes have been employed to control data access and process control flows. Due to the nature of testing possible at B-2, flexibility and configurability of systems has been central to the architecture during modernization.

Modernization of B-2 Data, Video, and Control Systems Infrastructure

NASA Technical Reports Server (NTRS)

Cmar, Mark D.; Maloney, Christian T.; Butala, Vishal D.

2012-01-01

The National Aeronautics and Space Administration (NASA) Glenn Research Center (GRC) Plum Brook Station (PBS) Spacecraft Propulsion Research Facility, commonly referred to as B-2, is NASA's third largest thermal-vacuum facility with propellant systems capability. B-2 has completed a modernization effort of its facility legacy data, video and control systems infrastructure to accommodate modern integrated testing and Information Technology (IT) Security requirements. Integrated systems tests have been conducted to demonstrate the new data, video and control systems functionality and capability. Discrete analog signal conditioners have been replaced by new programmable, signal processing hardware that is integrated with the data system. This integration supports automated calibration and verification of the analog subsystem. Modern measurement systems analysis (MSA) tools are being developed to help verify system health and measurement integrity. Legacy hard wired digital data systems have been replaced by distributed Fibre Channel (FC) network connected digitizers where high speed sampling rates have increased to 256,000 samples per second. Several analog video cameras have been replaced by digital image and storage systems. Hard-wired analog control systems have been replaced by Programmable Logic Controllers (PLC), fiber optic networks (FON) infrastructure and human machine interface (HMI) operator screens. New modern IT Security procedures and schemes have been employed to control data access and process control flows. Due to the nature of testing possible at B-2, flexibility and configurability of systems has been central to the architecture during modernization.

Automated System Calibration and Verification of the Position Measurements for the Los Alamos Isotope Production Facility and the Switchyard Kicker Facilities

NASA Astrophysics Data System (ADS)

Barr, D.; Gilpatrick, J. D.; Martinez, D.; Shurter, R. B.

2004-11-01

The Los Alamos Neutron Science Center (LANSCE) facility at Los Alamos National Laboratory has constructed both an Isotope Production Facility (IPF) and a Switchyard Kicker (XDK) as additions to the H+ and H- accelerator. These additions contain eleven Beam Position Monitors (BPMs) that measure the beam's position throughout the transport. The analog electronics within each processing module determines the beam position using the log-ratio technique. For system reliability, calibrations compensate for various temperature drifts and other imperfections in the processing electronics components. Additionally, verifications are periodically implemented by a PC running a National Instruments LabVIEW virtual instrument (VI) to verify continued system and cable integrity. The VI communicates with the processor cards via a PCI/MXI-3 VXI-crate communication module. Previously, accelerator operators performed BPM system calibrations typically once per day while beam was explicitly turned off. One of this new measurement system's unique achievements is its automated calibration and verification capability. Taking advantage of the pulsed nature of the LANSCE-facility beams, the integrated electronics hardware and VI perform calibration and verification operations between beam pulses without interrupting production beam delivery. The design, construction, and performance results of the automated calibration and verification portion of this position measurement system will be the topic of this paper.

Streamlining and integrating right-of-way and utility processes with planning, environmental, and design processes in Australia and Canada.

DOT National Transportation Integrated Search

2009-06-01

Many transportation projects require acquisition of land and accommodation of utility facilities in the : right-of-way. The Federal Highway Administration, American Association of State Highway and : Transportation Officials, and National Cooperative...

3S (Safeguards, Security, Safety) based pyroprocessing facility safety evaluation plan

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ku, J.H.; Choung, W.M.; You, G.S.

The big advantage of pyroprocessing for the management of spent fuels against the conventional reprocessing technologies lies in its proliferation resistance since the pure plutonium cannot be separated from the spent fuel. The extracted materials can be directly used as metal fuel in a fast reactor, and pyroprocessing reduces drastically the volume and heat load of the spent fuel. KAERI has implemented the SBD (Safeguards-By-Design) concept in nuclear fuel cycle facilities. The goal of SBD is to integrate international safeguards into the entire facility design process since the very beginning of the design phase. This paper presents a safety evaluationmore » plan using a conceptual design of a reference pyroprocessing facility, in which 3S (Safeguards, Security, Safety)-By-Design (3SBD) concept is integrated from early conceptual design phase. The purpose of this paper is to establish an advanced pyroprocessing hot cell facility design concept based on 3SBD for the successful realization of pyroprocessing technology with enhanced safety and proliferation resistance.« less

Life science payloads planning study integration facility survey results

NASA Technical Reports Server (NTRS)

Wells, G. W.; Brown, N. E.; Nelson, W. G.

1976-01-01

The integration facility survey effort described is structured to examine the facility resources needed to conduct life science payload (LSP) integration checkout activities at NASA-JSC. The LSP integration facility operations and functions are defined along with the LSP requirements for facility design. A description of available JSC life science facilities is presented and a comparison of accommodations versus requirements is reported.

The European Plate Observing System (EPOS): Integrating Thematic Services for Solid Earth Science

NASA Astrophysics Data System (ADS)

Atakan, Kuvvet; Bailo, Daniele; Consortium, Epos

2016-04-01

The mission of EPOS is to monitor and understand the dynamic and complex Earth system by relying on new e-science opportunities and integrating diverse and advanced Research Infrastructures in Europe for solid Earth Science. EPOS will enable innovative multidisciplinary research for a better understanding of the Earth's physical and chemical processes that control earthquakes, volcanic eruptions, ground instability and tsunami as well as the processes driving tectonics and Earth's surface dynamics. Through integration of data, models and facilities EPOS will allow the Earth Science community to make a step change in developing new concepts and tools for key answers to scientific and socio-economic questions concerning geo-hazards and geo-resources as well as Earth sciences applications to the environment and to human welfare. EPOS, during its Implementation Phase (EPOS-IP), will integrate multidisciplinary data into a single e-infrastructure. Multidisciplinary data are organized and governed by the Thematic Core Services (TCS) and are driven by various scientific communities encompassing a wide spectrum of Earth science disciplines. These include Data, Data-products, Services and Software (DDSS), from seismology, near fault observatories, geodetic observations, volcano observations, satellite observations, geomagnetic observations, as well as data from various anthropogenic hazard episodes, geological information and modelling. In addition, transnational access to multi-scale laboratories and geo-energy test-beds for low-carbon energy will be provided. TCS DDSS will be integrated into Integrated Core Services (ICS), a platform that will ensure their interoperability and access to these services by the scientific community as well as other users within the society. This requires dedicated tasks for interactions with the various TCS-WPs, as well as the various distributed ICS (ICS-Ds), such as High Performance Computing (HPC) facilities, large scale data storage facilities, complex processing and visualization tools etc. Computational Earth Science (CES) services are identified as a transversal activity and is planned to be harmonized and provided within the ICS. Currently a comprehensive requirements and use cases elicitation process is started through interactions with the ten different Thematic Core Service work packages. The results of this will be used to harmonize the DDSS elements and prepare for interoperability across the various disciplines. For this purpose a dedicated workshop is planned where the representatives of all the TCS communities will jointly discuss and agree upon the harmonization process. The technical integration of the DDSS elements to a metadata structure adopting CERIF (Common European Research Information Format) standards will start after the harmonization process is completed. Various levels of maturity in the handling and availability of TCS specific DDSS elements among the different TCS groups, is one of the most challenging aspects of this integration. For this reason a roadmap for integration is being prepared where most mature DDSS elements will be implemented during the next 2 years after a community driven testing and validation process. Integration of the remaining DDSS elements will be a continuously evolving process in the coming years.

MPLM Donatello is offloaded at the SLF

NASA Technical Reports Server (NTRS)

2001-01-01

At the Shuttle Landing Facility, cranes help offload the Italian Space Agency's Multi-Purpose Logistics Module Donatello from the Airbus '''Beluga''' air cargo plane. The third of three for the International Space Station, the module will be moved on a transporter to the Space Station Processing Facility for processing. Among the activities for the payload test team are integrated electrical tests with other Station elements in the SSPF, leak tests, electrical and software compatibility tests with the Space Shuttle (using the Cargo Integrated Test equipment) and an Interface Verification Test once the module is installed in the Space Shuttle's payload bay at the launch pad. The most significant mechanical task to be performed on Donatello in the SSPF is the installation and outfitting of the racks for carrying the various experiments and cargo.

KENNEDY SPACE CENTER, FLA. - STS-82 crew members examine part of the Flight Support System during the Crew Equipment Integration Test (CEIT) in KSC's Vertical Processing Facility. From left are Mission Specialists Steven L. Smith and Gregory J. Harbaugh and Payload Commander Mark C. Lee. Liftoff of STS-82, the second Hubble Space Telescope (HST) servicing mission, is scheduled Feb. 11 aboard Discovery with a crew of seven.

NASA Image and Video Library

1997-01-22

KENNEDY SPACE CENTER, FLA. - STS-82 crew members examine part of the Flight Support System during the Crew Equipment Integration Test (CEIT) in KSC's Vertical Processing Facility. From left are Mission Specialists Steven L. Smith and Gregory J. Harbaugh and Payload Commander Mark C. Lee. Liftoff of STS-82, the second Hubble Space Telescope (HST) servicing mission, is scheduled Feb. 11 aboard Discovery with a crew of seven.

Spectroscopic observations of nanosized TiO2 by the hydrothermal method

NASA Astrophysics Data System (ADS)

Zikriya, Mohamed; Nadaf, Y. F.; Bharathy, P. Vijai; Renuka, C. G.

2018-05-01

Metal oxides are useful materials that have various applications in advanced field such as, in view of their different properties, hardness, thermal dependability and compound resistance. Novel utilizations of the nanostructures of these oxides are drawing in critical enthusiasm as new preparation process are created and new structures are described. Hydrothermal synthesis is a fruitful procedure to prepare different sensitive structures of metal oxides on the scales from a couple to several nanometres, particularly, the hugely scattered middle structures which are hardly through pyro-preparation. Titanium dioxide nanocrystals are synthesis by a hydrolysis procedure of metatitanic acid. Nano precious crystal of different sizes is procure in the after calcinations from 150 to 225°C. Raman scattering was utilized to examine the advancement of the anatase stage in the nano crystal during calcinations.

20 CFR 404.1503a - Program integrity.

Code of Federal Regulations, 2010 CFR

2010-04-01

... is currently revoked or suspended by any State licensing authority pursuant to adequate due process... psychological consultant, consultative examination provider, or diagnostic test facility. Also see §§ 404.1519...

20 CFR 404.1503a - Program integrity.

Code of Federal Regulations, 2011 CFR

2011-04-01

... is currently revoked or suspended by any State licensing authority pursuant to adequate due process... psychological consultant, consultative examination provider, or diagnostic test facility. Also see §§ 404.1519...

Biogasification of Walt Disney World biomass waste blend. Annual report Jan-Dec 82

DOE Office of Scientific and Technical Information (OSTI.GOV)

Biljetina, R.; Chynoweth, D.P.; Janulis, J.

1983-05-01

The objective of this research is to develop efficient processes for conversion of biomass-waste blends to methane and other resources. To evaluate the technical and economic feasibility, an experimental test facility (ETU) is being designed and installed at the Reedy Creek Wastewater Treatment Plant at Walt Disney World, Orlando, Florida. The facility will integrate a biomethanogenic conversion process with a waste-water treatment process employing water hyacinth ponds for secondary and tertiary treatment of sewage produced at Walt Disney World. The ETU will be capable of feeding 1-wet ton per day of water hyacinth-sludge blends to the digestion system for productionmore » of methane and other byproducts. The detailed design of the facility has been completed and procurement of equipment is in progress.« less

Experiment/facility requirements document for the Space Station Furnace Facility. Section 1: Integrated configuration

NASA Astrophysics Data System (ADS)

1992-05-01

The function of the Space Station Furnace Facility (SSFF) is to support materials research into the crystal growth and solidification processes of electronic and photonic materials, metals and alloys, and glasses and ceramics. To support this broad base of research requirements, the SSFF will employ a variety of furnace modules which will be operated, regulated, and supported by a core of common subsystems. Furnace modules may be reconfigured or specifically developed to provide unique solidification conditions for each set of experiments. The SSFF modular approach permits the addition of new or scaled-up furnace modules to support the evolution of the facility as new science requirements are identified. The SSFF Core is of modular design to permit augmentation for enhanced capabilities. The fully integrated configuration of the SSFF will consist of three racks with the capability of supporting up to two furnace modules per rack. The initial configuration of the SSFF will consist of two of the three racks and one furnace module. This Experiment/Facility Requirements Document (E/FRD) describes the integrated facility requirements for the Space Station Freedom (SSF) Integrated Configuration-1 (IC1) mission. The IC1 SSFF will consist of two racks: the Core Rack, with the centralized subsystem equipment; and the Experiment Rack-1, with Furnace Module-1 and the distributed subsystem equipment to support the furnace. The SSFF support functions are provided by the following Core subsystems: power conditioning and distribution subsystem (SSFF PCDS); data management subsystem (SSFF DMS); thermal control Subsystem (SSFF TCS); gas distribution subsystem (SSFF GDS); and mechanical structures subsystem (SSFF MSS).

Experiment/facility requirements document for the Space Station Furnace Facility. Section 1: Integrated configuration

NASA Technical Reports Server (NTRS)

1992-01-01

The function of the Space Station Furnace Facility (SSFF) is to support materials research into the crystal growth and solidification processes of electronic and photonic materials, metals and alloys, and glasses and ceramics. To support this broad base of research requirements, the SSFF will employ a variety of furnace modules which will be operated, regulated, and supported by a core of common subsystems. Furnace modules may be reconfigured or specifically developed to provide unique solidification conditions for each set of experiments. The SSFF modular approach permits the addition of new or scaled-up furnace modules to support the evolution of the facility as new science requirements are identified. The SSFF Core is of modular design to permit augmentation for enhanced capabilities. The fully integrated configuration of the SSFF will consist of three racks with the capability of supporting up to two furnace modules per rack. The initial configuration of the SSFF will consist of two of the three racks and one furnace module. This Experiment/Facility Requirements Document (E/FRD) describes the integrated facility requirements for the Space Station Freedom (SSF) Integrated Configuration-1 (IC1) mission. The IC1 SSFF will consist of two racks: the Core Rack, with the centralized subsystem equipment; and the Experiment Rack-1, with Furnace Module-1 and the distributed subsystem equipment to support the furnace. The SSFF support functions are provided by the following Core subsystems: power conditioning and distribution subsystem (SSFF PCDS); data management subsystem (SSFF DMS); thermal control Subsystem (SSFF TCS); gas distribution subsystem (SSFF GDS); and mechanical structures subsystem (SSFF MSS).

Low-Activity Waste Pretreatment System Additional Engineering-Scale Integrated Test Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Landon, Matt R.; Wilson, Robert A.

Washington River Protections Solutions, LLC’s (WRPS) Low Activity Waste Pretreatment System (LAWPS) Project provides for the early production of immobilized low-activity waste (ILAW) by feeding LAW directly from Tank Farms to the Waste Treatment and Immobilization Plant (WTP) LAW Facility, bypassing the WTP Pretreatment Facility. Prior to the transfer of feed to the WTP LAW Vitrification Facility, tank supernatant waste will be pretreated in the LAWPS to meet the WTP LAW waste acceptance criteria (WAC). Full-scale and engineering-scale testing of critical technology elements, as part of the technology maturation process, are components of the overall LAWPS Project. WRPS awarded themore » engineering-scale integrated testing scope to AECOM via WRPS Subcontract 58349. This report is deliverable MSR-008 of the subcontract.« less

Space Station Furnace Facility. Experiment/Facility Requirements Document (E/FRD), volume 2, appendix 5

NASA Technical Reports Server (NTRS)

Kephart, Nancy

1992-01-01

The function of the Space Station Furnace Facility (SSFF) is to support materials research into the crystal growth and solidification processes of electronic and photonic materials, metals and alloys, and glasses and ceramics. To support this broad base of research requirements, the SSFF will employ a variety of furnace modules operated, regulated, and supported by a core of common subsystems. Furnace modules may be reconfigured or specifically developed to provide unique solidifcation conditions for each set of experiments. The SSFF modular approach permits the addition of new or scaled-up furnace modules to support the evolution of the facility as new science requirements are identified. The SSFF Core is of modular design to permit augmentation for enhanced capabilities. The fully integrated configuration of the SSFF will consist of three racks with the capability of supporting up to two furnace modules per rack. The initial configuration of the SSFF will consist of two of the three racks and one furnace module. This Experiment/Facility Requirements Document (E/FRD) describes the integrated facility requirements for the Space Station Freedom (SSF) Integrated Configuration-1 (IC1) mission. The IC1 SSFF will consist of two racks: the Core Rack, with the centralized subsystem equipment, and the Experiment Rack-1, with Furnace Module-1 and the distributed subsystem equipment to support the furnace.

KSC-02pd0695

NASA Image and Video Library

2002-05-15

KENNEDY SPACE CENTER, FLA. - In the Orbiter Processing Facility, FAA Administrator Patti Smith (second from left) listens to Jim Halsell (right), manager of KSC's Space Shuttle Program Launch Integration, during a tour of KSC.

Integrate Evaluation into the Planning Process.

ERIC Educational Resources Information Center

Camp, William

1985-01-01

In an attempt to correct for limitations in the Program Evaluation and Review Technique-Critical Path Method (PERT-CPM), the Graphical Evaluation and Review Technique (GERT) has been developed. This management tool allows for evaluation during the facilities' development process. Two figures and two references are provided. (DCS)

Emissions model of waste treatment operations at the Idaho Chemical Processing Plant

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schindler, R.E.

1995-03-01

An integrated model of the waste treatment systems at the Idaho Chemical Processing Plant (ICPP) was developed using a commercially-available process simulation software (ASPEN Plus) to calculate atmospheric emissions of hazardous chemicals for use in an application for an environmental permit to operate (PTO). The processes covered by the model are the Process Equipment Waste evaporator, High Level Liquid Waste evaporator, New Waste Calcining Facility and Liquid Effluent Treatment and Disposal facility. The processes are described along with the model and its assumptions. The model calculates emissions of NO{sub x}, CO, volatile acids, hazardous metals, and organic chemicals. Some calculatedmore » relative emissions are summarized and insights on building simulations are discussed.« less

Grid Facilities | Grid Modernization | NREL

Science.gov Websites

groundbreaking innovations and collaboration in grid research. Photo of the Energy Systems Integration Facility Energy Systems Integration Facility The Energy Systems Integration Facility is the nation's premier user Located in Boulder, Colorado, the National Wind Technology Center (NWTC) offers similar integration

System integration of marketable subsystems

NASA Technical Reports Server (NTRS)

1978-01-01

These monthly reports, covering the period February 1978 through June 1978, describe the progress made in the major areas of the program. The areas covered are: systems integration of marketable subsystems; development, design, and building of site data acquisition subsystems; development and operation of the central data processing system; operation of the MSFC Solar Test Facility; and systems analysis.

Advanced Electronic Technology

DTIC Science & Technology

1977-11-15

Electronics 15 III. Materials Research 15 TV. Microelectronics 16 V. Surface- Wave Technology 16 DATA SYSTEMS DIVISION 2 INTRODUCTION This...Processing Digital Voice Processing Packet Speech Wideband Integrated Voice/Data Technology Radar Signal Processing Technology Nuclear Safety Designs...facilities make it possible to track the status of these jobs, retrieve their job control language listings, and direct a copy of printed or punched

Data management and its role in delivering science at DOE BES user facilities - Past, Present, and Future

NASA Astrophysics Data System (ADS)

Miller, Stephen D.; Herwig, Kenneth W.; Ren, Shelly; Vazhkudai, Sudharshan S.; Jemian, Pete R.; Luitz, Steffen; Salnikov, Andrei A.; Gaponenko, Igor; Proffen, Thomas; Lewis, Paul; Green, Mark L.

2009-07-01

The primary mission of user facilities operated by Basic Energy Sciences under the Department of Energy is to produce data for users in support of open science and basic research [1]. We trace back almost 30 years of history across selected user facilities illustrating the evolution of facility data management practices and how these practices have related to performing scientific research. The facilities cover multiple techniques such as X-ray and neutron scattering, imaging and tomography sciences. Over time, detector and data acquisition technologies have dramatically increased the ability to produce prolific volumes of data challenging the traditional paradigm of users taking data home upon completion of their experiments to process and publish their results. During this time, computing capacity has also increased dramatically, though the size of the data has grown significantly faster than the capacity of one's laptop to manage and process this new facility produced data. Trends indicate that this will continue to be the case for yet some time. Thus users face a quandary for how to manage today's data complexity and size as these may exceed the computing resources users have available to themselves. This same quandary can also stifle collaboration and sharing. Realizing this, some facilities are already providing web portal access to data and computing thereby providing users access to resources they need [2]. Portal based computing is now driving researchers to think about how to use the data collected at multiple facilities in an integrated way to perform their research, and also how to collaborate and share data. In the future, inter-facility data management systems will enable next tier cross-instrument-cross facility scientific research fuelled by smart applications residing upon user computer resources. We can learn from the medical imaging community that has been working since the early 1990's to integrate data from across multiple modalities to achieve better diagnoses [3] - similarly, data fusion across BES facilities will lead to new scientific discoveries.

The Design of PSB-VVER Experiments Relevant to Accident Management

NASA Astrophysics Data System (ADS)

Nevo, Alessandro Del; D'Auria, Francesco; Mazzini, Marino; Bykov, Michael; Elkin, Ilya V.; Suslov, Alexander

Experimental programs carried-out in integral test facilities are relevant for validating the best estimate thermal-hydraulic codes(1), which are used for accident analyses, design of accident management procedures, licensing of nuclear power plants, etc. The validation process, in fact, is based on well designed experiments. It consists in the comparison of the measured and calculated parameters and the determination whether a computer code has an adequate capability in predicting the major phenomena expected to occur in the course of transient and/or accidents. University of Pisa was responsible of the numerical design of the 12 experiments executed in PSB-VVER facility (2), operated at Electrogorsk Research and Engineering Center (Russia), in the framework of the TACIS 2.03/97 Contract 3.03.03 Part A, EC financed (3). The paper describes the methodology adopted at University of Pisa, starting form the scenarios foreseen in the final test matrix until the execution of the experiments. This process considers three key topics: a) the scaling issue and the simulation, with unavoidable distortions, of the expected performance of the reference nuclear power plants; b) the code assessment process involving the identification of phenomena challenging the code models; c) the features of the concerned integral test facility (scaling limitations, control logics, data acquisition system, instrumentation, etc.). The activities performed in this respect are discussed, and emphasis is also given to the relevance of the thermal losses to the environment. This issue affects particularly the small scaled facilities and has relevance on the scaling approach related to the power and volume of the facility.

Design and construction of coal/biomass to liquids (CBTL) process development unit (PDU) at the University of Kentucky Center for Applied Energy Research (CAER)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Placido, Andrew; Liu, Kunlei; Challman, Don

This report describes a first phase of a project to design, construct and commission an integrated coal/biomass-to-liquids facility at a capacity of 1 bbl. /day at the University of Kentucky Center for Applied Energy Research (UK-CAER) – specifically for construction of the building and upstream process units for feed handling, gasification, and gas cleaning, conditioning and compression. The deliverables from the operation of this pilot plant [when fully equipped with the downstream process units] will be firstly the liquid FT products and finished fuels which are of interest to UK-CAER’s academic, government and industrial research partners. The facility will producemore » research quantities of FT liquids and finished fuels for subsequent Fuel Quality Testing, Performance and Acceptability. Moreover, the facility is expected to be employed for a range of research and investigations related to: Feed Preparation, Characteristics and Quality; Coal and Biomass Gasification; Gas Clean-up/ Conditioning; Gas Conversion by FT Synthesis; Product Work-up and Refining; Systems Analysis and Integration; and Scale-up and Demonstration. Environmental Considerations - particularly how to manage and reduce carbon dioxide emissions from CBTL facilities and from use of the fuels - will be a primary research objectives. Such a facility has required significant lead time for environmental review, architectural/building construction, and EPC services. UK, with DOE support, has advanced the facility in several important ways. These include: a formal EA/FONSI, and permits and approvals; construction of a building; selection of a range of technologies and vendors; and completion of the upstream process units. The results of this project are the FEED and detailed engineering studies, the alternate configurations and the as-built plant - its equipment and capabilities for future research and demonstration and its adaptability for re-purposing to meet other needs. These are described in some detail in this report, along with lessons learned.« less

An Airbus arrives at KSC with third MPLM

NASA Technical Reports Server (NTRS)

2001-01-01

An Airbus '''Beluga''' air cargo plane, The Super Transporter, lands at KSC's Shuttle Landing Facility. Its cargo, from the factory of Alenia Aerospazio in Turin, Italy, is the Italian Space Agency's Multi-Purpose Logistics Module Donatello, the third of three for the International Space Station. The module will be transported to the Space Station Processing Facility for processing. Among the activities for the payload test team are integrated electrical tests with other Station elements in the SSPF, leak tests, electrical and software compatibility tests with the Space Shuttle (using the Cargo Integrated Test equipment) and an Interface Verification Test once the module is installed in the Space Shuttle's payload bay at the launch pad. The most significant mechanical task to be performed on Donatello in the SSPF is the installation and outfitting of the racks for carrying the various experiments and cargo.

An Airbus arrives at KSC with third MPLM

NASA Technical Reports Server (NTRS)

2001-01-01

An Airbus '''Beluga''' air cargo plane, The Super Transporter, arrives at KSC's Shuttle Landing Facility from the factory of Alenia Aerospazio in Turin, Italy. Its cargo is the Italian Space Agency's Multi-Purpose Logistics Module Donatello, the third of three for the International Space Station. The module will be transported to the Space Station Processing Facility for processing. Among the activities for the payload test team are integrated electrical tests with other Station elements in the SSPF, leak tests, electrical and software compatibility tests with the Space Shuttle (using the Cargo Integrated Test equipment) and an Interface Verification Test once the module is installed in the Space Shuttle's payload bay at the launch pad. The most significant mechanical task to be performed on Donatello in the SSPF is the installation and outfitting of the racks for carrying the various experiments and cargo.

KSC-98pc150

NASA Image and Video Library

1998-01-14

The Photovoltaic Module 1 Integrated Equipment Assembly (IEA) is moved through Kennedy Space Center’s Space Station Processing Facility (SSPF) toward the workstand where it will be processed for flight on STS-97, scheduled for launch in April 1999. The IEA is one of four integral units designed to generate, distribute, and store power for the International Space Station. It will carry solar arrays, power storage batteries, power control units, and a thermal control system. The 16-foot-long, 16,850-pound unit is now undergoing preflight preparations in the SSPF

KSC-98pc154

NASA Image and Video Library

1998-01-14

The Photovoltaic Module 1 Integrated Equipment Assembly (IEA) is lowered into its workstand at Kennedy Space Center’s Space Station Processing Facility (SSPF), where it will be processed for flight on STS-97, scheduled for launch in April 1999. The IEA is one of four integral units designed to generate, distribute, and store power for the International Space Station. It will carry solar arrays, power storage batteries, power control units, and a thermal control system. The 16-foot-long, 16,850-pound unit is now undergoing preflight preparations in the SSPF

Integrated intelligent sensor for the textile industry

NASA Astrophysics Data System (ADS)

Peltie, Philippe; David, Dominique

1996-08-01

A new sensor has been developed for pantyhose inspection. Unlike a first complete inspection machine devoted to post- manufacturing control of the whole panty, this sensor will be directly integrated on currently existing manufacturing machines, and will combine advantages of miniaturization is to design an intelligent, compact and very cheap product, which should be integrated without requiring any modifications of host machines. The sensor part was designed to achieve closed acquisition, and various solutions have been explored to maintain adequate depth of field. The illumination source will be integrated in the device. The processing part will include correction facilities and electronic processing. Finally, high-level information will be output in order to interface directly with the manufacturing machine automate.

Take a Tour of Our Facility | Energy Systems Integration Facility | NREL

Science.gov Websites

Take a Tour of Our Facility Take a Tour of Our Facility The Energy Systems Integration Facility Optical Characterization Laboratory System Performance Laboratory Power Systems Integration Laboratory Control Room Energy Storage Laboratory Outdoor Testing Areas Outdoor Testing Areas Energy Systems

Photodynamic Molecular Beacons: An Image-Guided Therapeutic Approach to Breast Cancer Vertebral Metastases

DTIC Science & Technology

2011-03-01

pyropheophorbide carboxylic acid succinimidyl ester (Pyro- NHS) was prepared according to a published procedure (18). Other chemicals were obtained from Aldrich...2) a polycation and a polyanion attached to each end of the linker, forming a “zipper” structure via electrostatic attraction, (3) pyropheophorbide as...is achievable by simply switching D to a fluorescent photosensitizer, such as pyropheophorbide . The ZMBs will then possess novel targeting

Improvised Incendiary Devices: Risk Assessment, Threats, Vulnerabilities and Consequences

DTIC Science & Technology

2006-09-01

terrorism, Baird substitutes “the unlawful use of force and violence ” with “the use of incendiary attacks” to intimidate or coerce a government, the...targeting of noncombatants; political motivation; violence with 35 ALF/ELF, Arson Around with Auntie A.L.F: Your Guide for Putting the Heat on Animal...contends that future pyro-terrorist attacks will lean toward unrestrained violence for maximum psychological impact and challenge the conventional

Integrated exhaust gas analysis system for aircraft turbine engine component testing

NASA Technical Reports Server (NTRS)

Summers, R. L.; Anderson, R. C.

1985-01-01

An integrated exhaust gas analysis system was designed and installed in the hot-section facility at the Lewis Research Center. The system is designed to operate either manually or automatically and also to be operated from a remote station. The system measures oxygen, water vapor, total hydrocarbons, carbon monoxide, carbon dioxide, and oxides of nitrogen. Two microprocessors control the system and the analyzers, collect data and process them into engineering units, and present the data to the facility computers and the system operator. Within the design of this system there are innovative concepts and procedures that are of general interest and application to other gas analysis tasks.

Close-in characteristics of LH2/LOX reactions

NASA Technical Reports Server (NTRS)

Riehl, W. A.; Ullian, L. J.

1985-01-01

In deriving shock overpressures from space vehicles employing LH2 and LOX, separate methods of analyses and prediction are recommended, as a function of the distance. Three methods of treatment are recommended. For the Far Field - where the expected shock overpressure is less than 40 psi (lambda = 5) - use the classical PYRO approach to determine TNT yield, and employ classical ordnance (Kingery) curve to obtain the overall value. For the Close-In Range, a suggested limit is 3D, or a zone from a distance of three times the tank diameter to the tank wall. Rather than estimate a specific distance from the center of explosion to the target, it is only necessary to estimate whether this could be within one, two, or three diameters away from the wall; i.e., in the 1, 2, or 3D zone. Then assess whether mixing mode is by the PYRO CBGS (spill) mode or CBM (internal mixing) mode. From the zone and mixing mode, the probability of attaining various shock overpressures is determined from the plots provided herein. For the transition zone, between 40 psi and the 3D distance, it is tentatively recommended that both of the preceding methods be used, and to be conservative, the higher resulting value be used.

The Advanced Technology Development Center (ATDC)

NASA Technical Reports Server (NTRS)

Clements, G. R.; Willcoxon, R. (Technical Monitor)

2001-01-01

NASA is building the Advanced Technology Development Center (ATDC) to provide a 'national resource' for the research, development, demonstration, testing, and qualification of Spaceport and Range Technologies. The ATDC will be located at Space Launch Complex 20 (SLC-20) at Cape Canaveral Air Force Station (CCAFS) in Florida. SLC-20 currently provides a processing and launch capability for small-scale rockets; this capability will be augmented with additional ATDC facilities to provide a comprehensive and integrated in situ environment. Examples of Spaceport Technologies that will be supported by ATDC infrastructure include densified cryogenic systems, intelligent automated umbilicals, integrated vehicle health management systems, next-generation safety systems, and advanced range systems. The ATDC can be thought of as a prototype spaceport where industry, government, and academia, in partnership, can work together to improve safety of future space initiatives. The ATDC is being deployed in five separate phases. Major ATDC facilities will include a Liquid Oxygen Area; a Liquid Hydrogen Area, a Liquid Nitrogen Area, and a multipurpose Launch Mount; 'Iron Rocket' Test Demonstrator; a Processing Facility with a Checkout and Control System; and Future Infrastructure Developments. Initial ATDC development will be completed in 2006.

Mass tracking and material accounting in the integral fast reactor (IFR)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Orechwa, Y.; Adams, C.H.; White, A.M.

1991-01-01

This paper reports on the Integral Fast Reactor (IFR) which is a generic advanced liquid metal cooled reactor concept being developed at Argonne National Laboratory. There are a number of technical features of the IFR which contribute to its potential as a next-generation reactor. These are associated with large safety margins with regard to off-normal events involving the heat transport system, and the use of metallic fuel which makes possible the utilization of innovative fuel cycle processes. The latter feature permits fuel cycle closure with compact, low-cost reprocessing facilities, collocated with the reactor plant. These primary features are being demonstratedmore » in the facilities at ANL-West, utilizing Experimental Breeder Reactor II and the associated Fuel Cycle Facility (FCF) as an IFR prototype. The demonstration of this IFR prototype includes the design and implementation of the Mass-tracking System (MTG). In this system, data from the operations of the FCF, including weights and batch-process parameters, are collected and maintained by the MTG running on distributed workstations.« less

An Overview of Opportunities for Waste Heat Recovery and Thermal Integration in the Primary Aluminum Industry

NASA Astrophysics Data System (ADS)

Nowicki, Cassandre; Gosselin, Louis

2012-08-01

Efficient smelters currently consume roughly 13 MWh of electricity per ton of aluminum, while roughly half of that energy is lost as thermal waste. Although waste heat is abundant, current thermal integration in primary aluminum facilities remains limited. This is due to both the low quality of waste heat available and the shortage of potential uses within reasonable distance of identified waste heat sources. In this article, we present a mapping of both heat dissipation processes and heat demands around a sample facility (Alcoa Deschambault Quebec smelter). Our primary aim is to report opportunities for heat recovery and integration in the primary aluminum industry. We consider potential heat-to-sink pairings individually and assess their thermodynamic potential for producing energy savings.

Discharge documentation of patients discharged to subacute facilities: a three-year quality improvement process across an integrated health care system.

PubMed

Gandara, Esteban; Ungar, Jonathan; Lee, Jason; Chan-Macrae, Myrna; O'Malley, Terrence; Schnipper, Jeffrey L

2010-06-01

Effective communication among physicians during hospital discharge is critical to patient care. Partners Healthcare (Boston) has been engaged in a multi-year process to measure and improve the quality of documentation of all patients discharged from its five acute care hospitals to subacute facilities. Partners first engaged stakeholders to develop a consensus set of 12 required data elements for all discharges to subacute facilities. A measurement process was established and later refined. Quality improvement interventions were then initiated to address measured deficiencies and included education of physicians and nurses, improvements in information technology, creation of or improvements in discharge documentation templates, training of hospitalists to serve as role models, feedback to physicians and their service chiefs regarding reviewed cases, and case manager review of documentation before discharge. To measure improvement in quality as a result of these efforts, rates of simultaneous inclusion of all 12 applicable data elements ("defect-free rate") were analyzed over time. Some 3,101 discharge documentation packets of patients discharged to subacute facilities from January 1, 2006, through September 2008 were retrospectively studied. During the 11 monitored quarters, the defect-free rate increased from 65% to 96% (p < .001 for trend). The largest improvements were seen in documentation of preadmission medication lists, allergies, follow-up, and warfarin information. Institution of rigorous measurement, feedback, and multidisciplinary, multimodal quality improvement processes improved the inclusion of data elements in discharge documentation required for safe hospital discharge across a large integrated health care system.

Advanced High-Level Waste Glass Research and Development Plan

DOE Office of Scientific and Technical Information (OSTI.GOV)

Peeler, David K.; Vienna, John D.; Schweiger, Michael J.

2015-07-01

The U.S. Department of Energy Office of River Protection (ORP) has implemented an integrated program to increase the loading of Hanford tank wastes in glass while meeting melter lifetime expectancies and process, regulatory, and product quality requirements. The integrated ORP program is focused on providing a technical, science-based foundation from which key decisions can be made regarding the successful operation of the Hanford Tank Waste Treatment and Immobilization Plant (WTP) facilities. The fundamental data stemming from this program will support development of advanced glass formulations, key process control models, and tactical processing strategies to ensure safe and successful operations formore » both the low-activity waste (LAW) and high-level waste (HLW) vitrification facilities with an appreciation toward reducing overall mission life. The purpose of this advanced HLW glass research and development plan is to identify the near-, mid-, and longer-term research and development activities required to develop and validate advanced HLW glasses and their associated models to support facility operations at WTP, including both direct feed and full pretreatment flowsheets. This plan also integrates technical support of facility operations and waste qualification activities to show the interdependence of these activities with the advanced waste glass (AWG) program to support the full WTP mission. Figure ES-1 shows these key ORP programmatic activities and their interfaces with both WTP facility operations and qualification needs. The plan is a living document that will be updated to reflect key advancements and mission strategy changes. The research outlined here is motivated by the potential for substantial economic benefits (e.g., significant increases in waste throughput and reductions in glass volumes) that will be realized when advancements in glass formulation continue and models supporting facility operations are implemented. Developing and applying advanced glass formulations will reduce the cost of Hanford tank waste management by reducing the schedule for tank waste treatment and reducing the amount of HLW glass for storage, transportation, and disposal. Additional benefits will be realized if advanced glasses are developed that demonstrate more tolerance for key components in the waste (such as Al 2O 3, Cr 2O 3, SO 3 and Na 2O) above the currently defined WTP constraints. Tolerating these higher concentrations of key waste loading limiters may reduce the burden on (or even eliminate the need for) leaching to remove Cr and Al and washing to remove excess S and Na from the HLW fraction. Advanced glass formulations may also make direct vitrification of the HLW fraction without significant pretreatment more cost effective. Finally, the advanced glass formulation efforts seek not only to increase waste loading in glass, but also to increase glass production rate. When coupled with higher waste loading, ensuring that all of the advanced glass formulations are processable at or above the current contract processing rate leads to significant improvements in waste throughput (the amount of waste being processed per unit time),which could significantly reduce the overall WTP mission life. The integration of increased waste loading, reduced leaching/washing requirements, and improved melting rates provides a system-wide approach to improve the effectiveness of the WTP process.« less

KSC-98pc783

NASA Image and Video Library

1998-07-06

KSC Center Director Roy D. Bridges Jr. and U.S. Congressman Dave Weldon (holding scissors) cut the ribbon at a ceremony on July 6 to open KSC's new 34,600-square-foot Space Shuttle Main Engine Processing Facility (SSMEPF). Joining in the ribbon cutting are (left) Ed Adamek, vice president and associate program manager for Ground Operations of United Space Alliance; Marvin L. Jones, director of Installation Operations; Donald R. McMonagle, manager of Launch Integration; (right) Wade Ivey of Ivey Construction, Inc.; Robert B. Sieck, director of Shuttle Processing; and John Plowden, vice president of Rocketdyne. A major addition to the existing Orbiter Processing Facility Bay 3, the SSMEPF replaces the Shuttle Main Engine Shop located in the Vehicle Assembly Building (VAB). The decision to move the shop out of the VAB was prompted by safety considerations and recent engine processing improvements. The first three main engines to be processed in the new facility will fly on Shuttle Endeavour's STS-88 mission in December 1998

The SSMEPF opens with a ribbon-cutting ceremony

NASA Technical Reports Server (NTRS)

1998-01-01

Participants in the ribbon cutting for KSC's new 34,600-square- foot Space Shuttle Main Engine Processing Facility (SSMEPF) pose in front of a Space Shuttle Main Engine on display for the ceremony. From left, they are Ed Adamek, vice president and associate program manager for Ground Operations of United Space Alliance; John Plowden, vice president of Rocketdyne; Donald R. McMonagle, manager of Launch Integration; U.S. Congressman Dave Weldon; KSC Center Director Roy D. Bridges Jr.; Wade Ivey of Ivey Construction, Inc.; and Robert B. Sieck, director of Shuttle Processing. A major addition to the existing Orbiter Processing Facility Bay 3, the SSMEPF replaces the Shuttle Main Engine Shop located in the Vehicle Assembly Building (VAB). The decision to move the shop out of the VAB was prompted by safety considerations and recent engine processing improvements. The first three main engines to be processed in the new facility will fly on Shuttle Endeavour's STS-88 mission in December 1998.

The SSMEPF opens with a ribbon-cutting ceremony

NASA Technical Reports Server (NTRS)

1998-01-01

KSC Center Director Roy D. Bridges Jr. and U.S. Congressman Dave Weldon (holding scissors) cut the ribbon at a ceremony on July 6 to open KSC's new 34,600-square-foot Space Shuttle Main Engine Processing Facility (SSMEPF). Joining in the ribbon cutting are (left) Ed Adamek, vice president and associate program manager for Ground Operations of United Space Alliance; Marvin L. Jones, director of Installation Operations; Donald R. McMonagle, manager of Launch Integration; (right) Wade Ivey of Ivey Construction, Inc.; Robert B. Sieck, director of Shuttle Processing; and John Plowden, vice president of Rocketdyne. A major addition to the existing Orbiter Processing Facility Bay 3, the SSMEPF replaces the Shuttle Main Engine Shop located in the Vehicle Assembly Building (VAB). The decision to move the shop out of the VAB was prompted by safety considerations and recent engine processing improvements. The first three main engines to be processed in the new facility will fly on Shuttle Endeavour's STS-88 mission in December 1998.

Office of River Protection Advanced Low-Activity Waste Glass Research and Development Plan

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kruger, A. A.; Peeler, D. K.; Kim, D. S.

2015-11-23

The U.S. Department of Energy Office of River Protection (ORP) has initiated and leads an integrated Advanced Waste Glass (AWG) program to increase the loading of Hanford tank wastes in glass while meeting melter lifetime expectancies and process, regulatory, and product performance requirements. The integrated ORP program is focused on providing a technical, science-based foundation for making key decisions regarding the successful operation of the Hanford Tank Waste Treatment and Immobilization Plant (WTP) facilities in the context of an optimized River Protection Project (RPP) flowsheet. The fundamental data stemming from this program will support development of advanced glass formulations, keymore » product performance and process control models, and tactical processing strategies to ensure safe and successful operations for both the low-activity waste (LAW) and high-level waste vitrification facilities. These activities will be conducted with the objective of improving the overall RPP mission by enhancing flexibility and reducing cost and schedule.« less

Energy Systems Integration Newsletter | Energy Systems Integration Facility

Science.gov Websites

-one that other utilities, even in mainland states, will be able to follow as they embark on their own distributed energy resources (DERs), is one example of this process. With leadership from NREL, the IEEE P1547 Working Group completed revisions to the standard in the fall of 2017 after four years of significant

S3/S4 Integrated Truss being moved into the Space Shuttle Payloa

NASA Image and Video Library

2007-02-07

In the Space Station Processing Facility, an overhead crane moves the S3/S4 integrated truss to a payload canister. After it is stowed in the canister, the S3/S4 truss will be transported to the launch pad. The truss is the payload on mission STS-117, targeted for launch on March 15.

S3/S4 Integrated Truss being moved into the Space Shuttle Payloa

NASA Image and Video Library

2007-02-07

In the Space Station Processing Facility, an overhead crane settles the S3/S4 integrated truss into the payload canister. After it is stowed in the canister, the S3/S4 truss will be transported to the launch pad. The truss is the payload on mission STS-117, targeted for launch on March 15.

Specifications of a Simulation Model for a Local Area Network Design in Support of a Stock Point Logistics Integrated Communication Environment (SPLICE).

DTIC Science & Technology

1983-06-01

constrained at each step. Use of dis- crete simulation can be a powerful tool in this process if its role is carefully planned. The gross behavior of the...by projecting: - the arrival of units of work at SPLICE processing facilities (workload analysis) . - the amount of processing resources comsumed in

NASA's Habitat Demonstration Unit (HDU) Pressurized Excursion Module (PEM) In-Field Demonstration at Desert RATS 2010

NASA Technical Reports Server (NTRS)

Tri, Terry O.; Kennedy, Kriss J.; Toups, Larry; Gill, Tracy R.; Howe, A. Scott

2011-01-01

This paper describes the construction, assembly, subsystem integration, transportation, and field testing operations associated with the Habitat Demonstration Unit (HDU) Pressurized Excursion Module (PEM) and discusses lessons learned. In a one-year period beginning summer 2009, a tightly scheduled design-develop-build process was utilized by a small NASA "tiger team" to produce the functional HDU-PEM prototype in time to participate in the 2010 Desert Research and Technology Studies (Desert RATS) field campaign. The process required the coordination of multiple teams, subcontractors, facility management and safety staff. It also required a well-choreographed material handling and transportation process to deliver the finished product from the NASA-Johnson Space Center facilities to the remote Arizona desert locations of the field test. Significant findings of this paper include the team s greater understanding of the HDU-PEM s many integration issues and the in-field training the team acquired which will enable the implementation of the next-generation of improvements and development of high-fidelity field operations in a harsh environment. The Desert RATS analog environment is being promoted by NASA as an efficient means to design, build, and integrate multiple technologies in a mission architecture context, with the eventual goal of evolving the technologies into robust flight hardware systems. The HDU-PEM in-field demonstration at Desert RATS 2010 provided a validation process for the integration team, which has already begun to retool for the 2011 field tests that require an adapted architecture.

Strategic interaction among hospitals and nursing facilities: the efficiency effects of payment systems and vertical integration.

PubMed

Banks, D; Parker, E; Wendel, J

2001-03-01

Rising post-acute care expenditures for Medicare transfer patients and increasing vertical integration between hospitals and nursing facilities raise questions about the links between payment system structure, the incentive for vertical integration and the impact on efficiency. In the United States, policy-makers are responding to these concerns by initiating prospective payments to nursing facilities, and are exploring the bundling of payments to hospitals. This paper develops a static profit-maximization model of the strategic interaction between the transferring hospital and a receiving nursing facility. This model suggests that the post-1984 system of prospective payment for hospital care, coupled with nursing facility payments that reimburse for services performed, induces inefficient under-provision of hospital services and encourages vertical integration. It further indicates that the extension of prospective payment to nursing facilities will not eliminate the incentive to vertically integrate, and will not result in efficient production unless such integration takes place. Bundling prospective payments for hospitals and nursing facilities will neither remove the incentive for vertical integration nor induce production efficiency without such vertical integration. However, bundled payment will induce efficient production, with or without vertical integration, if nursing facilities are reimbursed for services performed. Copyright 2001 John Wiley & Sons, Ltd.

Facilities Condition and Hazards Assessment for Materials and Fuel Complex Facilities MFC-799, 799A, and 770C

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gary Mecham; Don Konoyer

2009-11-01

The Materials & Fuel Complex (MFC) facilities 799 Sodium Processing Facility (a single building consisting of two areas: the Sodium Process Area (SPA) and the Carbonate Process Area (CPA), 799A Caustic Storage Area, and 770C Nuclear Calibration Laboratory have been declared excess to future Department of Energy mission requirements. Transfer of these facilities from Nuclear Energy to Environmental Management, and an associated schedule for doing so, have been agreed upon by the two offices. The prerequisites for this transfer to occur are the removal of nonexcess materials and chemical inventory, deinventory of the calibration source in MFC-770C, and the reroutingmore » and/or isolation of utility and service systems. This report provides a description of the current physical condition and any hazards (material, chemical, nuclear or occupational) that may be associated with past operations of these facilities. This information will document conditions at time of transfer of the facilities from Nuclear Energy to Environmental Management and serve as the basis for disposition planning. The process used in obtaining this information included document searches, interviews and facility walk-downs. A copy of the facility walk-down checklist is included in this report as Appendix A. MFC-799/799A/770C are all structurally sound and associated hazardous or potentially hazardous conditions are well defined and well understood. All installed equipment items (tanks, filters, etc.) used to process hazardous materials remain in place and appear to have maintained their integrity. There is no evidence of leakage and all openings are properly sealed or closed off and connections are sound. The pits appear clean with no evidence of cracking or deterioration that could lead to migration of contamination. Based upon the available information/documentation reviewed and the overall conditions observed during the facilities walk-down, it is concluded that these facilities may be disposed of at minimal risk to human health, safety or the environment.« less

GIS Facility and Services at the Ronald Greeley Center for Planetary Studies

NASA Astrophysics Data System (ADS)

Nelson, D. M.; Williams, D. A.

2017-06-01

At the RGCPS, we established a Geographic Information Systems (GIS) computer laboratory, where we instruct researchers how to use GIS and image processing software. Seminars demonstrate viewing, integrating, and digitally mapping planetary data.

Hardware development process for Human Research facility applications

NASA Astrophysics Data System (ADS)

Bauer, Liz

2000-01-01

The simple goal of the Human Research Facility (HRF) is to conduct human research experiments on the International Space Station (ISS) astronauts during long-duration missions. This is accomplished by providing integration and operation of the necessary hardware and software capabilities. A typical hardware development flow consists of five stages: functional inputs and requirements definition, market research, design life cycle through hardware delivery, crew training, and mission support. The purpose of this presentation is to guide the audience through the early hardware development process: requirement definition through selecting a development path. Specific HRF equipment is used to illustrate the hardware development paths. .

Orion Stage Adapter Arrival

NASA Image and Video Library

2018-04-03

NASA's Super Guppy aircraft touches down at the Shuttle Landing Facility at the agency's Kennedy Space Center in Florida. The Super Guppy is carrying the Orion Stage Adapter (OSA), the second flight-hardware section of NASA's Space Launch System (SLS) rocket that has arrived at Kennedy. The OSA will connect the Orion spacecraft to the upper part of the SLS rocket, the interim cryogenic propulsion stage (ICPS). Both the OSA and ICPS are being stored for processing in the center's Space Station Processing Facility in preparation for Exploration Mission-1, the first uncrewed, integrated launch of the SLS rocket and Orion spacecraft.

Orion Stage Adapter Arrival

NASA Image and Video Library

2018-04-03

NASA's Super Guppy aircraft taxies onto the tarmac after touching down at the Shuttle Landing Facility at the agency's Kennedy Space Center in Florida. The Super Guppy is carrying the Orion Stage Adapter (OSA), the second flight-hardware section of NASA's Space Launch System (SLS) rocket that has arrived at Kennedy. The OSA will connect the Orion spacecraft to the upper part of the SLS rocket, the interim cryogenic propulsion stage (ICPS). Both the OSA and ICPS are being stored for processing in the center's Space Station Processing Facility in preparation for Exploration Mission-1, the first uncrewed, integrated launch of the SLS rocket and Orion spacecraft.

Orion Stage Adapter Arrival

NASA Image and Video Library

2018-04-03

NASA's Super Guppy aircraft glides to a stop at the Shuttle Landing Facility at the agency's Kennedy Space Center in Florida. The Super Guppy is carrying the Orion Stage Adapter (OSA), the second flight-hardware section of NASA's Space Launch System (SLS) rocket that has arrived at Kennedy. The OSA will connect the Orion spacecraft to the upper part of the SLS rocket, the interim cryogenic propulsion stage (ICPS). Both the OSA and ICPS are being stored for processing in the center's Space Station Processing Facility in preparation for Exploration Mission-1, the first uncrewed, integrated launch of the SLS rocket and Orion spacecraft.

Orion Stage Adapter Arrival

NASA Image and Video Library

2018-04-03

NASA's Super Guppy aircraft prepares to touch down at the Shuttle Landing Facility at the agency's Kennedy Space Center in Florida. The Super Guppy is carrying the Orion Stage Adapter (OSA), the second flight-hardware section of NASA's Space Launch System (SLS) rocket that has arrived at Kennedy. The OSA will connect the Orion spacecraft to the upper part of the SLS rocket, the interim cryogenic propulsion stage (ICPS). Both the OSA and ICPS are being stored for processing in the center's Space Station Processing Facility in preparation for Exploration Mission-1, the first uncrewed, integrated launch of the SLS rocket and Orion spacecraft.

An Airbus arrives at KSC with third MPLM

NASA Technical Reports Server (NTRS)

2001-01-01

An Airbus '''Beluga''' air cargo plane, The Super Transporter, taxis onto the parking apron at KSC's Shuttle Landing Facility. Its cargo, from the factory of Alenia Aerospazio in Turin, Italy, is the Italian Space Agency's Multi-Purpose Logistics Module Donatello, the third of three for the International Space Station. The module will be transported to the Space Station Processing Facility for processing. Among the activities for the payload test team are integrated electrical tests with other Station elements in the SSPF, leak tests, electrical and software compatibility tests with the Space Shuttle (using the Cargo Integrated Test equipment) and an Interface Verification Test once the module is installed in the Space Shuttle's payload bay at the launch pad. The most significant mechanical task to be performed on Donatello in the SSPF is the installation and outfitting of the racks for carrying the various experiments and cargo.

MPLM Donatello is offloaded at the SLF

NASA Technical Reports Server (NTRS)

2001-01-01

At the Shuttle Landing Facility, workers in cherry pickers (right) help guide offloading of the Italian Space Agency's Multi-Purpose Logistics Module Donatello from the Airbus '''Beluga''' air cargo plane that brought it from the factory of Alenia Aerospazio in Turin, Italy. The third of three for the International Space Station, the module will be transported to the Space Station Processing Facility for processing. Among the activities for the payload test team are integrated electrical tests with other Station elements in the SSPF, leak tests, electrical and software compatibility tests with the Space Shuttle (using the Cargo Integrated Test equipment) and an Interface Verification Test once the module is installed in the Space Shuttle's payload bay at the launch pad. The most significant mechanical task to be performed on Donatello in the SSPF is the installation and outfitting of the racks for carrying the various experiments and cargo.

KSC01pp0234

NASA Image and Video Library

2001-02-01

An Airbus “Beluga” air cargo plane, The Super Transporter, taxis onto the parking apron at KSC’s Shuttle Landing Facility. Its cargo, from the factory of Alenia Aerospazio in Turin, Italy, is the Italian Space Agency’s Multi-Purpose Logistics Module Donatello, the third of three for the International Space Station. The module will be transported to the Space Station Processing Facility for processing. Among the activities for the payload test team are integrated electrical tests with other Station elements in the SSPF, leak tests, electrical and software compatibility tests with the Space Shuttle (using the Cargo Integrated Test equipment) and an Interface Verification Test once the module is installed in the Space Shuttle’s payload bay at the launch pad. The most significant mechanical task to be performed on Donatello in the SSPF is the installation and outfitting of the racks for carrying the various experiments and cargo

Model-centered approach to early planning and design of an eco-industrial park around an oil refinery.

PubMed

Zhang, Xiangping; Strømman, Anders H; Solli, Christian; Hertwich, Edgar G

2008-07-01

Industrial symbiosis promises environmental and economic gains through a utilization of the waste of some processes as a resource for other processes. Because of the costs and difficulties of transporting some wastes, the largest theoretical potential for industrial symbiosis is given when facilities are colocated in an eco-industrial park (EIP). This study proposes a model-centered approach with an eight-step procedure for the early planning and design of an eco-industrial park considering technical and environmental factors. Chemical process simulation software was used to model the energy and material flows among the prospective members and to quantify the benefits of integration among different firms in terms of energy and resources saved as compared to a reference situation. Process simulation was based on a combination of physical models of industrial processes and empirical models. The modeling allows for the development and evaluation of different collaboration opportunities and configurations. It also enables testing chosen configurations under hypothetical situations or external conditions. We present a case study around an existing oil and gas refinery in Mongstad, Norway. We used the approach to propose the colocation of a number of industrial facilities around the refinery, focused on integrating energy use among the facilities. An EIP with six main members was designed and simulated, matching new hypothetical members in size to the existing operations, modeling material and energy flows in the EIP, and assessing these in terms of carbon and hydrogen flows.

Automated baseline change detection -- Phases 1 and 2. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Byler, E.

1997-10-31

The primary objective of this project is to apply robotic and optical sensor technology to the operational inspection of mixed toxic and radioactive waste stored in barrels, using Automated Baseline Change Detection (ABCD), based on image subtraction. Absolute change detection is based on detecting any visible physical changes, regardless of cause, between a current inspection image of a barrel and an archived baseline image of the same barrel. Thus, in addition to rust, the ABCD system can also detect corrosion, leaks, dents, and bulges. The ABCD approach and method rely on precise camera positioning and repositioning relative to the barrelmore » and on feature recognition in images. The ABCD image processing software was installed on a robotic vehicle developed under a related DOE/FETC contract DE-AC21-92MC29112 Intelligent Mobile Sensor System (IMSS) and integrated with the electronics and software. This vehicle was designed especially to navigate in DOE Waste Storage Facilities. Initial system testing was performed at Fernald in June 1996. After some further development and more extensive integration the prototype integrated system was installed and tested at the Radioactive Waste Management Facility (RWMC) at INEEL beginning in April 1997 through the present (November 1997). The integrated system, composed of ABCD imaging software and IMSS mobility base, is called MISS EVE (Mobile Intelligent Sensor System--Environmental Validation Expert). Evaluation of the integrated system in RWMC Building 628, containing approximately 10,000 drums, demonstrated an easy to use system with the ability to properly navigate through the facility, image all the defined drums, and process the results into a report delivered to the operator on a GUI interface and on hard copy. Further work is needed to make the brassboard system more operationally robust.« less

Integrated Work Management: FOD/RLM, Course 31882

DOE Office of Scientific and Technical Information (OSTI.GOV)

Simpson, Lewis Edward

The facility operations director (FOD) and responsible line manager (RLM) play leadership and functional roles in the integrated work management (IWM) process at Los Alamos National Laboratory (LANL). This course, Integrated Work Management: FOD/RLM (COURSE 31882), describes the IWM roles and responsibilities of the FOD and the RLM; it also discusses IWM requirements that must be met by the FOD and the RLM. Before taking this course, you may want to take COURSE 31881, Integrated Work Management: Overview. This self-study course would be particularly helpful if you are unfamiliar with the IWM process. You should also read Procedure (P) 300,more » Integrated Work Management. This course briefly covers the roles of the preparer and person in charge (PIC). For more in-depth instruction on the preparer’s role, see COURSE 31883, Integrated Work Management: Preparer. For instruction on the PIC’s role, see COURSE 31884, Integrated Work Management: PIC.« less

Development of Lipid-based Nanoparticles for in vivo Targeted Delivery of Imaging Agents into Breast Cancer Cells

DTIC Science & Technology

2010-04-01

Fab to recognize pOV8-K b proteins on the surface of live cells, mouse lym phoma cell line EL4 was pulse d with either cognate (pOV8) or irrelevant...120 0.5 3 M FI Time, hour M FI Figure 11. Binding specificity of Pyro-NP-Fab. EL4 cells sensitized with peptide pOV8 ( ) but not with VSV

Characterization of the animal by-product meal industry in Costa Rica: Manufacturing practices through the production chain and food safety.

PubMed

Leiva, A; Granados-Chinchilla, F; Redondo-Solano, M; Arrieta-González, M; Pineda-Salazar, E; Molina, A

2018-06-01

Animal by-product rendering establishments are still relevant industries worldwide. Animal by-product meal safety is paramount to protect feed, animals, and the rest of the food chain from unwanted contamination. As microbiological contamination may arise from inadequate processing of slaughterhouse waste and deficiencies in good manufacturing practices within the rendering facilities, we conducted an overall establishment's inspection, including the product in several parts of the process.An evaluation of the Good Manufacturing Practices (GMP) was carried out, which included the location and access (i.e., admission) to the facilities, integrated pest management programs, physical condition of the facilities (e.g., infrastructure), equipments, vehicles and transportation, as well as critical control points (i.e., particle size and temperature set at 50 mm, 133°C at atmospheric pressure for 20 min, respectively) recommended by the OIE and the European Commission. The most sensitive points according to the evaluation are physical structure of the facilities (avg 42.2%), access to the facilities (avg 48.6%), and cleaning procedures (avg 51.4%).Also, indicator microorganisms (Salmonella spp., Clostridium spp., total coliforms, E. coli, E. coli O157:H7) were used to evaluate the safety in different parts of the animal meal production process. There was a prevalence of Salmonella spp. of 12.9, 14.3, and 33.3% in Meat and Bone Meal (MBM), poultry by-products, and fish meal, respectively. However, there were no significant differences (P = 0.73) in the prevalence between the different animal meals, according to the data collected.It was also observed that renderings associated with the poultry industry (i.e., 92.0%) obtained the best ratings overall, which reflects a satisfactory development of this sector and the integration of its production system as a whole.

Integration of Biosafety into Core Facility Management

PubMed Central

Fontes, Benjamin

2013-01-01

This presentation will discuss the implementation of biosafety policies for small, medium and large core laboratories with primary shared objectives of ensuring the control of biohazards to protect core facility operators and assure conformity with applicable state and federal policies, standards and guidelines. Of paramount importance is the educational process to inform core laboratories of biosafety principles and policies and to illustrate the technology and process pathways of the core laboratory for biosafety professionals. Elevating awareness of biohazards and the biosafety regulatory landscape among core facility operators is essential for the establishment of a framework for both project and material risk assessment. The goal of the biohazard risk assessment process is to identify the biohazard risk management parameters to conduct the procedure safely and in compliance with applicable regulations. An evaluation of the containment, protective equipment and work practices for the procedure for the level of risk identified is facilitated by the establishment of a core facility registration form for work with biohazards and other biological materials with potential risk. The final step in the biocontainment process is the assumption of Principal Investigator role with full responsibility for the structure of the site-specific biosafety program plan by core facility leadership. The presentation will provide example biohazard protocol reviews and accompanying containment measures for core laboratories at Yale University.

Quality assurance planning for lunar Mars exploration

NASA Technical Reports Server (NTRS)

Myers, Kay

1991-01-01

A review is presented of the tools and techniques required to meet the challenge of total quality in the goal of traveling to Mars and returning to the moon. One program used by NASA to ensure the integrity of baselined requirements documents is configuration management (CM). CM is defined as an integrated management process that documents and identifies the functional and physical characteristics of a facility's systems, structures, computer software, and components. It also ensures that changes to these characteristics are properly assessed, developed, approved, implemented, verified, recorded, and incorporated into the facility's documentation. Three principal areas are discussed that will realize significant efficiencies and enhanced effectiveness, change assessment, change avoidance, and requirements management.

Integrating the hospital information system (HIS) into the Austrian electronic health record ("ELGA") using the example of the health care facility "Breitenstein".

PubMed

Bonstingl, Martina

2014-01-01

The health care facility "Breitenstein" makes use of a hospital information system to coordinate clinical processes and document medical health data. So as to comply with novel Austrian legislation and fit the "ELGA" architecture, the system has to be adapted. This paper is based on a literature research and gives answers to technical and legal aspects of "ELGA". The introduction of an IHE connector and a CDA manager are the main changes to the current hospital information system. The implementation of interfaces that allow an integration of further "ELGA" features possible are the next step of the project.

Development and construction of a comprehensive set of research diagnostics for the FLARE user facility

NASA Astrophysics Data System (ADS)

Yoo, Jongsoo; Jara-Almonte, J.; Majeski, S.; Frank, S.; Ji, H.; Yamada, M.

2016-10-01

FLARE (Facility for Laboratory Reconnection Experiments) will be operated as a flexible user facility, and so a complete set of research diagnostics is under development, including magnetic probe arrays, Langmuir probes, Mach probes, spectroscopic probes, and a laser interferometer. In order to accommodate the various requirements of users, large-scale (1 m), variable resolution (0.5-4 cm) magnetic probes have been designed, and are currently being prototyped. Moreover, a fully fiber-coupled laser interferometer has been designed to measure the line-integrated electron density. This fiber-coupled interferometer system will reduce the complexity of alignment processes and minimize maintenance of the system. Finally, improvements to the electrostatic probes and spectroscopic probes currently used in the Magnetic Reconnection Experiment (MRX) are discussed. The specifications of other subsystems, such as integrators and digitizers, are also presented. This work is supported by DoE Contract No. DE-AC0209CH11466.

Enhance the pyroelectricity of polyvinylidene fluoride by graphene-oxide doping.

PubMed

Hu, Yuh-Chung; Hsu, Wei-Li; Wang, Yi-Ta; Ho, Cheng-Tao; Chang, Pei-Zen

2014-04-16

The high quality properties and benefits of graphene-oxide have generated an active area of research where many investigations have shown potential applications in various technological fields. This paper proposes a methodology for enhancing the pyro-electricity of PVDF by graphene-oxide doping. The PVDF film with graphene-oxide is prepared by the sol-gel method. Firstly, PVDF and graphene-oxide powders are dispersed into dimethylformamide as solvent to form a sol solution. Secondly, the sol solution is deposited on a flexible ITO/PET substrate by spin-coating. Thirdly, the particles in the sol solution are polymerized through baking off the solvent to produce a gel in a state of a continuous network of PVDF and graphene-oxide. The final annealing process pyrolyzes the gel and form a β-phase PVDF film with graphene-oxide doping. A complete study on the process of the graphene oxide doping of PVDF is accomplished. Some key points about the process are addressed based on experiments. The solutions to some key issues are found in this work, such as the porosity of film, the annealing temperature limitation by the use of flexible PET substrate, and the concentrations of PVDF and graphene-oxide.

S3/S4 Integrated Truss being moved into the Space Shuttle Payloa

NASA Image and Video Library

2007-02-07

In the Space Station Processing Facility, an overhead crane lowers the S3/S4 integrated truss into the open bay of the payload canister. After it is stowed in the canister, the S3/S4 truss will be transported to the launch pad. The truss is the payload on mission STS-117, targeted for launch on March 15.

S3/S4 Integrated Truss being moved into the Space Shuttle Payloa

NASA Image and Video Library

2007-02-07

In the Space Station Processing Facility, an overhead crane lowers the S3/S4 integrated truss toward the open doors of the payload canister. After it is stowed in the canister, the S3/S4 truss will be transported to the launch pad. The truss is the payload on mission STS-117, targeted for launch on March 15.

Identifying Therapeutics for Platinum-Resistant Ovarian Cancer by Next Generation Mechanotyping

DTIC Science & Technology

2017-09-01

period, we have successfully advanced and integrated the PMF technology into the Molecular Shared Screening Resource at UCLA, thereby establishing the...will validate the effects of the lead compounds on cisplatin- resistant ovarian cancer cells, including cellular and molecular analyses. 15. SUBJECT...throughput screening facility at UCLA, the Molecular Shared Screening Resource (MSSR). Due to technical hurdles in the integration process, and reduced

KSC-98pc155

NASA Image and Video Library

1998-01-14

The Photovoltaic Module 1 Integrated Equipment Assembly (IEA) is lifted from its container in Kennedy Space Center’s Space Station Processing Facility (SSPF) before it is moved into its workstand, where it will be processed for flight on STS-97, scheduled for launch in April 1999. The IEA is one of four integral units designed to generate, distribute, and store power for the International Space Station. It will carry solar arrays, power storage batteries, power control units, and a thermal control system. The 16-foot-long, 16,850-pound unit is now undergoing preflight preparations in the SSPF

KSC-98pc153

NASA Image and Video Library

1998-01-14

Workers in Kennedy Space Center’s Space Station Processing Facility (SSPF) observe the Photovoltaic Module 1 Integrated Equipment Assembly (IEA) as it moves past them on its way to its workstand, where it will be processed for flight on STS-97, scheduled for launch in April 1999. The IEA is one of four integral units designed to generate, distribute, and store power for the International Space Station. It will carry solar arrays, power storage batteries, power control units, and a thermal control system. The 16-foot-long, 16,850-pound unit is now undergoing preflight preparations in the SSPF

KSC-98pc151

NASA Image and Video Library

1998-01-14

The Photovoltaic Module 1 Integrated Equipment Assembly (IEA) is moved past a Pressurized Mating Adapter in Kennedy Space Center’s Space Station Processing Facility (SSPF) toward the workstand where it will be processed for flight on STS-97, scheduled for launch in April 1999. The IEA is one of four integral units designed to generate, distribute, and store power for the International Space Station. It will carry solar arrays, power storage batteries, power control units, and a thermal control system. The 16-foot-long, 16,850-pound unit is now undergoing preflight preparations in the SSPF

STS-117 Media Showcase

NASA Image and Video Library

2007-02-06

In the Space Station Processing Facility, the S3/S4 integrated truss segment is on display for the media. The starboard 3/4 truss segment will launch aboard Space Shuttle Atlantis on mission STS-117, targeted for March 15. The element will be added to the 11-segment integrated truss structure, the station's backbone. The integrated truss structure eventually will span more than 300 feet. The S3/S4 truss has two large solar arrays and will provide one-fourth of the total power generation for the completed station.

An Automated DAKOTA and VULCAN-CFD Framework with Application to Supersonic Facility Nozzle Flowpath Optimization

NASA Technical Reports Server (NTRS)

Axdahl, Erik L.

2015-01-01

Removing human interaction from design processes by using automation may lead to gains in both productivity and design precision. This memorandum describes efforts to incorporate high fidelity numerical analysis tools into an automated framework and applying that framework to applications of practical interest. The purpose of this effort was to integrate VULCAN-CFD into an automated, DAKOTA-enabled framework with a proof-of-concept application being the optimization of supersonic test facility nozzles. It was shown that the optimization framework could be deployed on a high performance computing cluster with the flow of information handled effectively to guide the optimization process. Furthermore, the application of the framework to supersonic test facility nozzle flowpath design and optimization was demonstrated using multiple optimization algorithms.

78 FR 7334 - Port Authority Access to Facility Vulnerability Assessments and the Integration of Security Systems

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-01

... to Facility Vulnerability Assessments and the Integration of Security Systems AGENCY: Coast Guard...-sharing measures. Security System Integration Alternatives Require each MTSA-regulated facility owner or... other forms of security system integration. Information Requested 1. We request comments on the...

Implementing facility-based kangaroo mother care services: lessons from a multi-country study in Africa

PubMed Central

2014-01-01

Background Some countries have undertaken programs that included scaling up kangaroo mother care. The aim of this study was to systematically evaluate the implementation status of facility-based kangaroo mother care services in four African countries: Malawi, Mali, Rwanda and Uganda. Methods A cross-sectional, mixed-method research design was used. Stakeholders provided background information at national meetings and in individual interviews. Facilities were assessed by means of a standardized tool previously applied in other settings, employing semi-structured key-informant interviews and observations in 39 health care facilities in the four countries. Each facility received a score out of a total of 30 according to six stages of implementation progress. Results Across the four countries 95 per cent of health facilities assessed demonstrated some evidence of kangaroo mother care practice. Institutions that fared better had a longer history of kangaroo mother care implementation or had been developed as centres of excellence or had strong leaders championing the implementation process. Variation existed in the quality of implementation between facilities and across countries. Important factors identified in implementation are: training and orientation; supportive supervision; integrating kangaroo mother care into quality improvement; continuity of care; high-level buy in and support for kangaroo mother care implementation; and client-oriented care. Conclusion The integration of kangaroo mother care into routine newborn care services should be part of all maternal and newborn care initiatives and packages. Engaging ministries of health and other implementing partners from the outset may promote buy in and assist with the mobilization of resources for scaling up kangaroo mother care services. Mechanisms for monitoring these services should be integrated into existing health management information systems. PMID:25001366

ESIF Call for High-Impact Integrated Projects | Energy Systems Integration

Science.gov Websites

Integrated Projects As a U.S. Department of Energy user facility, the Energy Systems Integration Facility concepts, tools, and technologies needed to measure, analyze, predict, protect, and control the grid of the Facility | NREL ESIF Call for High-Impact Integrated Projects ESIF Call for High-Impact

Lithospheric Structure and Dynamics: Insights Facilitated by the IRIS/PASSCAL Facility

NASA Astrophysics Data System (ADS)

Meltzer, A.

2002-12-01

Through the development of community-based facilities in portable array seismology, a wide-range of seismic methods are now standard tools for imaging the Earth's interior, extending geologic observations made at the surface to depth. The IRIS/PASSCAL program provides the seismological community with the ability to routinely field experimental programs, from high-resolution seismic reflection profiling of the near surface to lithospheric scale imaging with both active and passive source arrays, to understand the tectonic evolution of continents, how they are assembled, disassembled, and modified through time. As our ability to record and process large volumes of data has improved we have moved from simple 1-D velocity models and 2-D structural cross sections of the subsurface to 3-D and 4-D images to correlate complex surface tectonics to processes in the Earth's interior. Data from individual IRIS/PASSCAL experiments has fostered multidisciplinary studies, bringing together geologists, geochemists, and geophysicists to work together on common problems. As data is collected from a variety of tectonic environments around the globe common elements begin to emerge. We now recognize and study the inherent lateral and vertical heterogeneity in the crust and mantle lithosphere and its role in controlling deformation, the importance of low velocity mobile mantle in supporting topography, and the importance of fluids and fluid migration in magmatic and deformational processes. We can image and map faults, fault zones, and fault networks to study them as systems rather than isolated planes of deformation to better understand earthquake nucleation, rupture, and propagation. An additional benefit of these community-based facilities is the pooling of resources to develop effective and sustainable education and outreach programs. These programs attract new students to pursue careers in earth science, engage the general public in the scientific enterprise, raise the profile of the earth sciences, and reveal the importance of earth processes in shaping the environment in which we live. Future challenges facing our community include continued evolution of existing facilities to keep pace with scientific inquiry, routinely utilizing fully 3-D and where appropriate 4-D data sets to understand earth structure and dynamics, and the manipulation, and analysis of large multidisciplinary data sets. Community models should be considered as a mechanism to integrate, analyze, and share data and results within a process oriented framework. Exciting developments on the horizon include EarthScope. To maximize the potential for significant advances in our understanding of tectonic processes, observations from new EarthScope facilities must be integrated with additional geologic data sets of similar quality and resolution. New real-time data streams combined with new data integration, analysis, and visualization tools will provide us with the ability to integrate data across a continuous range of spatial scales providing a new and coherent view of lithospheric dynamics from local to plate scale.

Experiments on water detritiation and cryogenic distillation at TLK; Impact on ITER fuel cycle subsystems interfaces

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cristescu, I.; Cristescu, I. R.; Doerr, L.

2008-07-15

The ITER Isotope Separation System (ISS) and Water Detritiation System (WDS) should be integrated in order to reduce potential chronic tritium emissions from the ISS. This is achieved by routing the top (protium) product from the ISS to a feed point near the bottom end of the WDS Liquid Phase Catalytic Exchange (LPCE) column. This provides an additional barrier against ISS emissions and should mitigate the memory effects due to process parameter fluctuations in the ISS. To support the research activities needed to characterize the performances of various components for WDS and ISS processes under various working conditions and configurationsmore » as needed for ITER design, an experimental facility called TRENTA representative of the ITER WDS and ISS protium separation column, has been commissioned and is in operation at TLK The experimental program on TRENTA facility is conducted to provide the necessary design data related to the relevant ITER operating modes. The operation availability and performances of ISS-WDS have impact on ITER fuel cycle subsystems with consequences on the design integration. The preliminary experimental data on TRENTA facility are presented. (authors)« less

Canadian macromolecular crystallography facility: a suite of fully automated beamlines.

PubMed

Grochulski, Pawel; Fodje, Michel; Labiuk, Shaunivan; Gorin, James; Janzen, Kathryn; Berg, Russ

2012-06-01

The Canadian light source is a 2.9 GeV national synchrotron radiation facility located on the University of Saskatchewan campus in Saskatoon. The small-gap in-vacuum undulator illuminated beamline, 08ID-1, together with the bending magnet beamline, 08B1-1, constitute the Canadian Macromolecular Crystallography Facility (CMCF). The CMCF provides service to more than 50 Principal Investigators in Canada and the United States. Up to 25% of the beam time is devoted to commercial users and the general user program is guaranteed up to 55% of the useful beam time through a peer-review process. CMCF staff provides "Mail-In" crystallography service to users with the highest scored proposals. Both beamlines are equipped with very robust end-stations including on-axis visualization systems, Rayonix 300 CCD series detectors and Stanford-type robotic sample auto-mounters. MxDC, an in-house developed beamline control system, is integrated with a data processing module, AutoProcess, allowing full automation of data collection and data processing with minimal human intervention. Sample management and remote monitoring of experiments is enabled through interaction with a Laboratory Information Management System developed at the facility.

Environmental Health Assessment for Pyrotechnic Perchlorate Elimination/Mitigation Program for M118/M119 Simulators

DTIC Science & Technology

2009-09-11

evaluated. When toxicity data were not available, criteria were modeled using QSAR approaches. 3 Toxicology Report No. 87-XE-074Z-09C g. Potential...Environmental Health Assessment for Work Unit PYRO 06-08, Pyrotechnic Perchlorate Elimination/Mitigation Program for M118/M119 Simulators, Toxicology ...Directorate of Toxicology , Health Effects Research Program. He may be contacted at DSN (312) 584-7159 or commercial (410) 436-7159. FOR THE COMMANDER

Standard Rubbers for Chemical Defense Research. Volume 1. Formulation and Properties

DTIC Science & Technology

1989-01-01

by the military services. There is a growing need to determine the susceptibility of diese materials to the chemical threats anticipated from the...leading to a very weak signal which contains little spectral information. An alternative method involves very rapid pyrolysis of the rubber specimen to...After nitrogen gas purge of the pyrolysis cell, a small chunk of the rubber compound was heated at 600’C for 60 seconds by use of a Foxboro Pyro

Development of Lipid-Based Nanoparticles for In Vivo Targeted Delivery of Imaging Agents into Breast Cancer Cells

DTIC Science & Technology

2009-10-01

nanoparticles size of 8 nm; found out that shell loaded image is much more effective than core loaded one. We have prepared a number of lipid nanoparticles ...strategies: lipid - conjugated fluorochrome was introduced into either core or shell lipids of the nanoparticles . Pyro- CE-OA that contains cholesterol... lipids either in the core or in the shell . We have conjugated the nanoparticles with the integrin ligands. We have showed

A twice-as-smart synthetic G-quartet: PyroTASQ is both a smart quadruplex ligand and a smart fluorescent probe.

PubMed

Laguerre, Aurélien; Stefan, Loic; Larrouy, Manuel; Genest, David; Novotna, Jana; Pirrotta, Marc; Monchaud, David

2014-09-03

Recent and unambiguous evidences of the formation of DNA and RNA G-quadruplexes in cells has provided solid support for these structures to be considered as valuable targets in oncology. Beyond this, they have lent further credence to the anticancer strategies relying on small molecules that selectively target these higher-order DNA/RNA architectures, referred to as G-quadruplex ligands. They have also shed bright light on the necessity of designing multitasking ligands, displaying not only enticing quadruplex interacting properties (affinity, structural selectivity) but also additional features that make them usable for detecting quadruplexes in living cells, notably for determining whether, when, and where these structures fold and unfold during the cell cycle and also for better assessing the consequences of their stabilization by external agents. Herein, we report a brand new design of such multitasking ligands, whose structure experiences a quadruplex-promoted conformational switch that triggers not only its quadruplex affinity (i.e., smart ligands, which display high affinity and selectivity for DNA/RNA quadruplexes) but also its fluorescence (i.e., smart probes, which behave as selective light-up fluorescent reporters on the basis of a fluorogenic electron redistribution). The first prototype of such multifunctional ligands, termed PyroTASQ, represents a brand new generation of quadruplex ligands that can be referred to as "twice-as-smart" quadruplex ligands.

Public Participation Guide: Container Handling in the Port of Durban, South Africa

EPA Pesticide Factsheets

This case study describes the public participation process that was conducted in the context of an Integrated Environmental Management exercise related to the proposed expansion of container handling facilities at the Port of Durban, South Africa.

Research on common methods for evaluating the operation effect of integrated wastewater treatment facilities of iron and steel enterprises

NASA Astrophysics Data System (ADS)

Bingsheng, Xu

2017-04-01

Considering the large quantities of wastewater generated from iron and steel enterprises in China, this paper is aimed to research the common methods applied for evaluating the integrated wastewater treatment effect of iron and steel enterprises. Based on survey results on environmental protection performance, technological economy, resource & energy consumption, services and management, an indicator system for evaluating the operation effect of integrated wastewater treatment facilities is set up. By discussing the standards and industrial policies in and out of China, 27 key secondary indicators are further defined on the basis of investigation on main equipment and key processes for wastewater treatment, so as to determine the method for setting key quantitative and qualitative indicators for evaluation indicator system. It is also expected to satisfy the basic requirements of reasonable resource allocation, environmental protection and sustainable economic development, further improve the integrated wastewater treatment effect of iron and steel enterprises, and reduce the emission of hazardous substances and environmental impact.

Thermal Distribution System | Energy Systems Integration Facility | NREL

Science.gov Websites

Thermal Distribution System Thermal Distribution System The Energy Systems Integration Facility's integrated thermal distribution system consists of a thermal water loop connected to a research boiler and . Photo of the roof of the Energy Systems Integration Facility. The thermal distribution bus allows

K-BREF(Korean BAT reference document) development : BAT and BAT-AELs for large combustion plants and waste incinerators in Korea.

NASA Astrophysics Data System (ADS)

Yoo, Heungmin; Lee, Daegyun; Park, Jaehong

2017-04-01

Since the initial environmental policy namely "Regulation on assigning license for environmental pollutant emission facilities" was introduced in 1971, the previous environmental policy that assign licenses on emission facilities of each pollutant has been implementing in Korea. From this, economic standard and environmental quality of Korea are recognized as level of developed countries, even though various development activities for industrialization. However, amount of pollutant, emission route and emission source are increasing with development of various industries, and citizens recognition for environment have been changed as well. Thus, ministry of environment of Korea needs systematic policy based on scientific grounds for conversion of paradigm. For this, ministry of environment was introduced new policy namely "integrated pollution prevention and control(IPPC)", and it will be implemented from 2017 in Korea. IPPC is established for considering environment, economic and efficiency: 10 licenses on each pollutant emission will be integrated to one license, and it can be expected simplification for business licensing process. As well, this policy can be upgraded and processed while considering characteristics on location and industry types, in the future. However, to conduct this system harmoniously, policy demanders have to apply integrated control system to their facilities. Especially, the first applied industries by IPPC are two industries, such as large combustion plants for power generation and waste incineration facilities. Therefore, ministry of environment has to publish technical guideline books firstly for those industries, and they were named to "BAT reference document(BREF)". In this study, essential information for BREFs publishment, that is including emission levels, best available technique(BAT) and so on was investigated. In addition, the BAT-associated emission levels (BAT-AELs) of each industry were set using emission data obtained from realtime-monitoring system.

All-solid state, flexible, high-energy integrated hybrid micro-supercapacitors based on 3D LSG/CoNi2S4 nanosheets.

PubMed

Moosavifard, Seyyed Ebrahim; Shamsi, Javad; Altafi, Mohammad Kazem; Moosavifard, Zeinab Sadat

2016-11-18

3D LSG/CoNi 2 S 4 //LSG interdigitated microelectrodes have been firstly developed by a facile, scalable and low cost process for all-solid-state, flexible integrated asymmetric micro-supercapacitors. These devices can achieve energy densities of up to 49 W h l -1 which is comparable to those of lead acid batteries.

S3/S4 Integrated Truss being moved into the Space Shuttle Payloa

NASA Image and Video Library

2007-02-07

In the Space Station Processing Facility, workers attach an overhead crane to the S3/S4 integrated truss in order to move it to the payload canister. After it is stowed in the canister, the S3/S4 truss will be transported to the launch pad. The truss is the payload on mission STS-117, targeted for launch on March 15.

Process-driven selection of information systems for healthcare

NASA Astrophysics Data System (ADS)

Mills, Stephen F.; Yeh, Raymond T.; Giroir, Brett P.; Tanik, Murat M.

1995-05-01

Integration of networking and data management technologies such as PACS, RIS and HIS into a healthcare enterprise in a clinically acceptable manner is a difficult problem. Data within such a facility are generally managed via a combination of manual hardcopy systems and proprietary, special-purpose data processing systems. Process modeling techniques have been successfully applied to engineering and manufacturing enterprises, but have not generally been applied to service-based enterprises such as healthcare facilities. The use of process modeling techniques can provide guidance for the placement, configuration and usage of PACS and other informatics technologies within the healthcare enterprise, and thus improve the quality of healthcare. Initial process modeling activities conducted within the Pediatric ICU at Children's Medical Center in Dallas, Texas are described. The ongoing development of a full enterprise- level model for the Pediatric ICU is also described.

Evaluating building performance in healthcare facilities: an organizational perspective.

PubMed

Steinke, Claudia; Webster, Lynn; Fontaine, Marie

2010-01-01

Using the environment as a strategic tool is one of the most cost-effective and enduring approaches for improving public health; however, it is one that requires multiple perspectives. The purpose of this article is to highlight an innovative methodology that has been developed for conducting comprehensive performance evaluations in public sector health facilities in Canada. The building performance evaluation methodology described in this paper is a government initiative. The project team developed a comprehensive building evaluation process for all new capital health projects that would respond to the aforementioned need for stakeholders to be more accountable and to better integrate the larger organizational strategy of facilities. The Balanced Scorecard, which is a multiparadigmatic, performance-based business framework, serves as the underlying theoretical framework for this initiative. It was applied in the development of the conceptual model entitled the Building Performance Evaluation Scorecard, which provides the following benefits: (1) It illustrates a process to link facilities more effectively to the overall mission and goals of an organization; (2) It is both a measurement and a management system that has the ability to link regional facilities to measures of success and larger business goals; (3) It provides a standardized methodology that ensures consistency in assessing building performance; and (4) It is more comprehensive than traditional building evaluations. The methodology presented in this paper is both a measurement and management system that integrates the principles of evidence-based design with the practices of pre- and post-occupancy evaluation. It promotes accountability and continues throughout the life cycle of a project. The advantage of applying this framework is that it engages health organizations in clarifying a vision and strategy for their facilities and helps translate those strategies into action and measurable performance outcomes.

Molten salt applications in materials processing

NASA Astrophysics Data System (ADS)

Mishra, Brajendra; Olson, David L.

2005-02-01

The science of molten salt electrochemistry for electrowinning of reactive metals, such as calcium, and its in situ application in pyro-reduction has been described. Calcium electrowinning has been performed in a 5 10 wt% calcium oxide calcium chloride molten salt by the electrolytic dissociation of calcium oxide. This electrolysis requires the use of a porous ceramic sheath around the anode to keep the cathodically deposited calcium and the anodic gases separate. Stainless steel cathode and graphite anode have been used in the temperature range of 850 950 °C. This salt mixture is produced as a result of the direct oxide reduction (DOR) of reactive metal oxides by calcium in a calcium chloride bath. The primary purpose of this process is to recover the expensive calcium reductant and to recycle calcium chloride. Experimental data have been included to justify the suitability as well as limitations of the electrowinning process. Transport of oxygen ions through the sheath is found to be the rate controlling step. Under the constraints of the reactor design, a calcium recovery rate of approx. 150 g/h was achieved. Feasibility of a process to produce metals by pyrometallurgical reduction, using the calcium reductant produced electrolytically within the same reactor, has been shown in a hybrid process. Several processes are currently under investigation to use this electrowon calcium for in situ reduction of metal oxides.

KSC-2009-2311

NASA Image and Video Library

2009-03-26

CAPE CANAVERAL, Fla. – The first Ares I-X motor segment is in the Rotation, Processing and Surge Facility at NASA's Kennedy Space Center in Florida. It is one of four reusable motor segments and nozzle exit cone shipped by the Ares I first-stage prime contractor Alliant Techsystems Inc. for final processing and integration in the facility. The booster used for the Ares I-X launch is being modified by adding new forward structures and a fifth segment simulator. The motor is the final hardware needed for the rocket's upcoming flight test this summer. The stacking operations are scheduled to begin in the Vehicle Assembly Building in April. Photo credit: NASA/Jim Grossmann

An Operator Perspective from a Facility Evaluation of an RFID-Based UF6 Cylinder Accounting and Tracking System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Martyn, Rose; Fitzgerald, Peter; Stehle, Nicholas D

An operational field test of a Radio-Frequency Identification (RFID) system for tracking and accounting UF6 cylinders was conducted at the Global Nuclear Fuel Americas (GNF) fuel fabrication plant in 2009. The Cylinder Accountability and Tracking System (CATS) was designed and deployed by Oak Ridge National Laboratory (ORNL) and evaluated in cooperation with GNF. The system required that passive RFID be attached to several UF6 30B cylinders as they were received at the site; then the cylinders were tracked as they proceeded to interim storage, to processing in an autoclave, and eventually to disposition from the site. This CATS deployment alsomore » provided a direct integration of scale data from the site accountability scales. The integration of this information into the tracking data provided an attribute for additional safeguards for evaluation. The field test provided insight into the advantages and challenges of using RFID at an operating nuclear facility. The RFID system allowed operators to interact with the technology and demonstrated the survivability of the tags and reader equipment in the process environment. This paper will provide the operator perspective on utilizing RFID technology for locating cylinders within the facility, thereby tracking the cylinders for process and for Material Control & Accounting functions. The paper also will present the operator viewpoint on RFID implemented as an independent safeguards system.« less

ICPS Removal from Shipping Container

NASA Image and Video Library

2017-03-09

Inside the United Launch Alliance (ULA) Horizontal Integration Facility at Cape Canaveral Air Force Station in Florida, a crane lifts the shipping container cover away from the Interim Cryogenic Propulsion Stage (ICPS) for NASA's Space Launch System rocket, followed by the ICPS bring removed and placed on a work stand for processing. The ICPS is the first integrated piece of flight hardware to arrive for the SLS. The ICPS arrived from the ULA facility in Decatur, Alabama. The ICPS is the in-space stage that is located toward the top of the rocket, between the Launch Vehicle Stage Adapter and the Orion Spacecraft Adapter. It will provide some of the in-space propulsion during Orion's first flight test atop the SLS on Exploration Mission 1.

The Chandra X-ray Observatory removed from its container in the Vertical Processing Facility

NASA Technical Reports Server (NTRS)

1999-01-01

Inside the Vertical Processing Facility (VPF), the overhead crane lifts Chandra X-ray Observatory completely out of its protective container. While in the VPF, the telescope will undergo final installation of associated electronic components; it will also be tested, fueled and mated with the Inertial Upper Stage booster. A set of integrated tests will follow. Chandra is scheduled for launch July 9 aboard Space Shuttle Columbia, on mission STS-93 . Formerly called the Advanced X-ray Astrophysics Facility, Chandra comprises three major elements: the spacecraft, the science instrument module (SIM), and the world's most powerful X-ray telescope. Chandra will allow scientists from around the world to see previously invisible black holes and high-temperature gas clouds, giving the observatory the potential to rewrite the books on the structure and evolution of our universe.

The Chandra X-ray Observatory removed from its container in the Vertical Processing Facility

NASA Technical Reports Server (NTRS)

1999-01-01

Inside the Vertical Processing Facility (VPF), workers begin lifting the Chandra X-ray Observatory out of its protective container. While in the VPF, the telescope will undergo final installation of associated electronic components; it will also be tested, fueled and mated with the Inertial Upper Stage booster. A set of integrated tests will follow. Chandra is scheduled for launch July 9 aboard Space Shuttle Columbia, on mission STS-93 . Formerly called the Advanced X-ray Astrophysics Facility, Chandra comprises three major elements: the spacecraft, the science instrument module (SIM), and the world's most powerful X-ray telescope. Chandra will allow scientists from around the world to see previously invisible black holes and high-temperature gas clouds, giving the observatory the potential to rewrite the books on the structure and evolution of our universe.

Integration and use of Microgravity Research Facility: Lessons learned by the crystals by vapor transport experiment and Space Experiments Facility programs

NASA Technical Reports Server (NTRS)

Heizer, Barbara L.

1992-01-01

The Crystals by Vapor Transport Experiment (CVTE) and Space Experiments Facility (SEF) are materials processing facilities designed and built for use on the Space Shuttle mid deck. The CVTE was built as a commercial facility owned by the Boeing Company. The SEF was built under contract to the UAH Center for Commercial Development of Space (CCDS). Both facilities include up to three furnaces capable of reaching 850 C minimum, stand-alone electronics and software, and independent cooling control. In addition, the CVTE includes a dedicated stowage locker for cameras, a laptop computer, and other ancillary equipment. Both systems are designed to fly in a Middeck Accommodations Rack (MAR), though the SEF is currently being integrated into a Spacehab rack. The CVTE hardware includes two transparent furnaces capable of achieving temperatures in the 850 to 870 C range. The transparent feature allows scientists/astronauts to directly observe and affect crystal growth both on the ground and in space. Cameras mounted to the rack provide photodocumentation of the crystal growth. The basic design of the furnace allows for modification to accommodate techniques other than vapor crystal growth. Early in the CVTE program, the decision was made to assign a principal scientist to develop the experiment plan, affect the hardware/software design, run the ground and flight research effort, and interface with the scientific community. The principal scientist is responsible to the program manager and is a critical member of the engineering development team. As a result of this decision, the hardware/experiment requirements were established in such a way as to balance the engineering and science demands on the equipment. Program schedules for hardware development, experiment definition and material selection, flight operations development and crew training, both ground support and astronauts, were all planned and carried out with the understanding that the success of the program science was as important as the hardware functionality. How the CVTE payload was designed and what it is capable of, the philosophy of including the scientists in design and operations decisions, and the lessons learned during the integration process are descussed.

Facility effluent monitoring plan for the plutonium uranium extraction facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wiegand, D.L.

A facility effluent monitoring plan is required by the US Department of Energy in DOE Order 5400.1 for any operations that involve hazardous materials and radioactive substances that could impact employee or public safety or the environment. This document is prepared using the specific guidelines identified in A Guide for Preparing Hanford Site Facility Effluent Monitoring Plans, WHC-EP-0438-01. This facility effluent monitoring plan assesses effluent monitoring systems and evaluates whether they are adequate to ensure the public health and safety as specified in applicable federal, state, and local requirements. This facility effluent monitoring plan shall ensure long-range integrity of themore » effluent monitoring systems by requiring an update whenever a new process or operation introduces new hazardous materials or significant radioactive materials. This document must be reviewed annually even if there are no operational changes, and it must be updated at a minimum of every three years.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dorr, Kent A.; Ostrom, Michael J.; Freeman-Pollard, Jhivaun R.

CH2M Hill Plateau Remediation Company (CHPRC) designed, constructed, commissioned, and began operation of the largest groundwater pump and treatment facility in the U.S. Department of Energy’s (DOE) nationwide complex. This one-of-a-kind groundwater pump and treatment facility, located at the Hanford Nuclear Reservation Site (Hanford Site) in Washington State, was built to an accelerated schedule with American Recovery and Reinvestment Act (ARRA) funds. There were many contractual, technical, configuration management, quality, safety, and Leadership in Energy and Environmental Design (LEED) challenges associated with the design, procurement, construction, and commissioning of this $95 million, 52,000 ft groundwater pump and treatment facility tomore » meet DOE’s mission objective of treating contaminated groundwater at the Hanford Site with a new facility by June 28, 2012. The project team’s successful integration of the project’s core values and green energy technology throughout design, procurement, construction, and start-up of this complex, first-of-its-kind Bio Process facility resulted in successful achievement of DOE’s mission objective, as well as attainment of LEED GOLD certification, which makes this Bio Process facility the first non-administrative building in the DOE Office of Environmental Management complex to earn such an award.« less

A proactive approach to sustainable management of mine tailings

NASA Astrophysics Data System (ADS)

Edraki, Mansour; Baumgartl, Thomas

2015-04-01

The reactive strategies to manage mine tailings i.e. containment of slurries of tailings in tailings storage facilities (TSF's) and remediation of tailings solids or tailings seepage water after the decommissioning of those facilities, can be technically inefficient to eliminate environmental risks (e.g. prevent dispersion of contaminants and catastrophic dam wall failures), pose a long term economic burden for companies, governments and society after mine closure, and often fail to meet community expectations. Most preventive environmental management practices promote proactive integrated approaches to waste management whereby the source of environmental issues are identified to help make a more informed decisions. They often use life cycle assessment to find the "hot spots" of environmental burdens. This kind of approach is often based on generic data and has rarely been used for tailings. Besides, life cycle assessments are less useful for designing operations or simulating changes in the process and consequent environmental outcomes. It is evident that an integrated approach for tailings research linked to better processing options is needed. A literature review revealed that there are only few examples of integrated approaches. The aim of this project is to develop new tailings management models by streamlining orebody characterization, process optimization and rehabilitation. The approach is based on continuous fingerprinting of geochemical processes from orebody to tailings storage facility, and benchmark the success of such proactive initiatives by evidence of no impacts and no future projected impacts on receiving environments. We present an approach for developing such a framework and preliminary results from a case study where combined grinding and flotation models developed using geometallurgical data from the orebody were constructed to predict the properties of tailings produced under various processing scenarios. The modelling scenarios based on the case study data provide the capacity to predict the composition of tailings and the resulting environmental management implications. For example, the type and content of clay minerals in tailings will affect the geotechnical stability and water recovery. Clay content will also influence decisions made for paste or thickened tailings and underground backfilling. It is possible by using an integrated assessment framework to evaluate more alternatives, including the production of additional saleable and benign streams, alternative tailings treatment and disposal, as well as options for reuse, recycling and pre-processing of existing tailings.

EPA Facility Registry Service (FRS): OIL

EPA Pesticide Factsheets

This dataset contains location and facility identification information from EPA's Facility Registry Service (FRS) for the subset of facilities that link to the Oil database. The Oil database contains information on Spill Prevention, Control, and Countermeasure (SPCC) and Facility Response Plan (FRP) subject facilities to prevent and respond to oil spills. FRP facilities are referred to as substantial harm facilities due to the quantities of oil stored and facility characteristics. FRS identifies and geospatially locates facilities, sites or places subject to environmental regulations or of environmental interest. Using vigorous verification and data management procedures, FRS integrates facility data from EPA's national program systems, other federal agencies, and State and tribal master facility records and provides EPA with a centrally managed, single source of comprehensive and authoritative information on facilities. This data set contains the subset of FRS integrated facilities that link to Oil facilities once the Oil data has been integrated into the FRS database. Additional information on FRS is available at the EPA website https://www.epa.gov/enviro/facility-registry-service-frs.

Magnetohydrodynamics (MHD) Engineering Test Facility (ETF) 200 MWe power plant. Design Requirements Document (DRD)

NASA Technical Reports Server (NTRS)

Rigo, H. S.; Bercaw, R. W.; Burkhart, J. A.; Mroz, T. S.; Bents, D. J.; Hatch, A. M.

1981-01-01

A description and the design requirements for the 200 MWe (nominal) net output MHD Engineering Test Facility (ETF) Conceptual Design, are presented. Performance requirements for the plant are identified and process conditions are indicated at interface stations between the major systems comprising the plant. Also included are the description, functions, interfaces and requirements for each of these major systems. The lastest information (1980-1981) from the MHD technology program are integrated with elements of a conventional steam electric power generating plant.

Space Station services and design features for users

NASA Technical Reports Server (NTRS)

Kurzhals, Peter R.; Mckinney, Royce L.

1987-01-01

The operational design features and services planned for the NASA Space Station will furnish, in addition to novel opportunities and facilities, lower costs through interface standardization and automation and faster access by means of computer-aided integration and control processes. By furnishing a basis for large-scale space exploitation, the Space Station will possess industrial production and operational services capabilities that may be used by the private sector for commercial ventures; it could also ultimately support lunar and planetary exploration spacecraft assembly and launch facilities.

KSC-98pc152

NASA Image and Video Library

1998-01-14

The Photovoltaic Module 1 Integrated Equipment Assembly (IEA) is moved past Node 1, seen at left, of the International Space Station (ISS) in Kennedy Space Center’s Space Station Processing Facility (SSPF). The IEA will be processed at the SSPF for flight on STS-97, scheduled for launch in April 1999. The IEA is one of four integral units designed to generate, distribute, and store power for the ISS. It will carry solar arrays, power storage batteries, power control units, and a thermal control system. The 16-foot-long, 16,850-pound unit is now undergoing preflight preparations in the SSPF

Integration between chemical oxidation and membrane thermophilic biological process.

PubMed

Bertanza, G; Collivignarelli, M C; Crotti, B M; Pedrazzani, R

2010-01-01

Full scale applications of activated sludge thermophilic aerobic process for treatment of liquid wastes are rare. This experimental work was carried out at a facility, where a thermophilic reactor (1,000 m(3) volume) is operated. In order to improve the global performance of the plant, it was decided to upgrade it, by means of two membrane filtration units (ultrafiltration -UF-, in place of the final sedimentation, and nanofiltration -NF-). Subsequently, the integration with chemical oxidation (O(3) and H(2)O(2)/UV processes) was taken into consideration. Studied solutions dealt with oxidation of both the NF effluents (permeate and concentrate). Based on experimental results and economic evaluation, an algorithm was proposed for defining limits of convenience of this process.

Liquid Propellant Blast Yields for Delta IV Heavy Vehicles

DTIC Science & Technology

2010-07-01

explode simultaneously, up to 1.4 million lb of liquid oxygen and liquid hydrogen (LO2/ LH2 ) may be involved and at least partially contribute to the...in the third so as to prevent them from contributing to the blast yield. Since the PYRO LO2/ LH2 yield model was originally developed using data from...that mixing interfaces between the LO2 and LH2 tanks for all three CBCs occur simultaneously, then a reasonable argument can be made for all three

Cost of Achieving Squad Overmatch by Training Resilience and Situational Awareness Skills that Optimize Human Performance and Discourage PTS and Suicide

DTIC Science & Technology

2015-12-01

actors. The study team canvassed commercial, academic, and research institutions for a possible surrogate solution and introduced wall based avatars ...barrel, tent, or market stand); other technologies such as wall-projected avatars are not used (instead role players are used). CACTF/MOUT must be...sites at each home station are fitted with mounts or docks to enable enhanced site technology (MILES-enabled wall- projected avatars , non-pyro effects

Explosive Bolt Dual-Initiated from One Side

NASA Technical Reports Server (NTRS)

Snow, Eric

2011-01-01

An explosive bolt has been developed that has a one-sided dual initiation train all the way down to the pyro charge for high reliability, while still allowing the other side of the bolt to remain in place after actuation to act as a thermal seal in an extremely high-temperature environment. This lightweight separation device separates at a single fracture plane, and has as much redundancy/reliability as possible. The initiation train comes into the explosive bolt from one side.

The ARM Climate Research Facility - New Capabilities and the Expected Impacts on Climate Science and Modeling

NASA Astrophysics Data System (ADS)

Voyles, J.; Mather, J. H.

2010-12-01

The ARM Climate Research Facility is a Department of Energy national scientific user facility. Research sites include fixed and mobile facilities, which collect research quality data for climate research. Through the American Recovery and Reinvestment Act of 2009, the U.S. Department of Energy’s Office of Science allocated $60 million to the ARM Climate Research Facility for the purchase of instruments and improvement of research sites. With these funds, ARM is in the process of deploying a broad variety of new instruments that will greatly enhance the measurement capabilities of the facility. New instruments being purchased include dual-frequency scanning cloud radars, scanning precipitation radars, Doppler lidars, a mobile Aerosol Observing System and many others. A list of instruments being purchased is available at http://www.arm.gov/about/recovery-act. Orders for all instruments have now been placed and activities are underway to integrate these new systems with our research sites. The overarching goal is to provide instantaneous and statistical measurements of the climate that can be used to advance the physical understanding and predictive performance of climate models. The Recovery Act investments enable the ARM Climate Research Facility to enhance existing and add new measurements, which enable a more complete understanding of the 3-dimensional evolution of cloud processes and related atmospheric properties. Understanding cloud processes are important globally, to reduce climate-modeling uncertainties and help improve our nation’s ability to manage climate impacts. Domer Plot of W-Band Reflectivity

Employees lower Cassini's upper experiment module and base onto a work stand in the PHSF

NASA Technical Reports Server (NTRS)

1997-01-01

Employees in the Payload Hazardous Servicing Facility (PHSF) lower the upper experiment module and base of the Cassini orbiter onto a work stand during prelaunch processing, testing and integration work in that facility. The Cassini orbiter and Huygens probe being processed at KSC are the two primary components of the Cassini spacecraft, which will be launched on a Titan IVB/Centaur expendable launch vehicle from Cape Canaveral Air Station. Cassini will explore Saturn, its rings and moons for four years. The Huygens probe, designed and developed for the European Space Agency (ESA), will be deployed from the orbiter to study the clouds, atmosphere and surface of Saturn's largest moon, Titan. The orbiter was designed and assembled at NASA's Jet Propulsion Laboratory in California. Following postflight inspections, integration of the 12 science instruments not already installed on the orbiter will be completed. Then, the parabolic high-gain antenna and the propulsion module will be mated to the orbiter, followed by the Huygens probe, which will complete spacecraft integration. The Cassini mission is targeted for an Oct. 6 launch to begin its 6.7-year journey to the Saturnian system. Arrival at the planet is expected to occur around July 1, 2004.

KSC-97pc729

NASA Image and Video Library

1997-04-22

An employee in the Payload Hazardous Servicing Facility (PHSF) sews thermal insulation material on the front heat shield of the Huygens probe during prelaunch processing testing and integration in that facility, with the probe’s back cover in the background. The Huygens probe and the Cassini orbiter being processed at KSC are the two primary components of the Cassini spacecraft, which will be launched on a Titan IVB/Centaur expendable launch vehicle from Cape Canaveral Air Station. Cassini will explore Saturn, its rings and moons for four years. The Huygens probe, designed and developed for the European Space Agency (ESA), will be deployed from the orbiter to study the clouds, atmosphere and surface of Saturn’s largest moon, Titan. The orbiter was designed and assembled at NASA’s Jet Propulsion Laboratory in California. Following postflight inspections, integration of the 12 science instruments not already installed on the orbiter will be completed. Then, the parabolic high-gain antenna and the propulsion module will be mated to the orbiter, followed by the Huygens probe, which will complete spacecraft integration. The Cassini mission is targeted for an Oct. 6 launch to begin its 6.7-year journey to the Saturnian system. Arrival at the planet is expected to occur around July 1, 2004

Development of an Integrated Leachate Treatment Solution for the Port Granby Waste Management Facility - 12429

DOE Office of Scientific and Technical Information (OSTI.GOV)

Conroy, Kevin W.; Vandergaast, Gerald

2012-07-01

The Port Granby Project (the Project) is located near the north shore of Lake Ontario in the Municipality of Clarington, Ontario, Canada. The Project consists of relocating approximately 450,000 m{sup 3} of historic Low-Level Radioactive Waste (LLRW) and contaminated soil from the existing Port Granby Waste Management Facility (WMF) to a proposed Long-Term Waste Management Facility (LTWMF) located adjacent to the WMF. The LTWMF will include an engineered waste containment facility, a Wastewater Treatment Plant (WTP), and other ancillary facilities. A series of bench- and pilot-scale test programs have been conducted to identify preferred treatment processes to be incorporated intomore » the WTP to treat wastewater generated during the construction, closure and post-closure periods at the WMF/LTWMF. (authors)« less

Transuranic Waste Processing Center (TWPC) Legacy Tank RH-TRU Sludge Processing and Compliance Strategy - 13255

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rogers, Ben C.; Heacker, Fred K.; Shannon, Christopher

2013-07-01

The U.S. Department of Energy (DOE) needs to safely and efficiently treat its 'legacy' transuranic (TRU) waste and mixed low-level waste (LLW) from past research and defense activities at the Oak Ridge National Laboratory (ORNL) so that the waste is prepared for safe and secure disposal. The TWPC operates an Environmental Management (EM) waste processing facility on the Oak Ridge Reservation (ORR). The TWPC is classified as a Hazard Category 2, non-reactor nuclear facility. This facility receives, treats, and packages low-level waste and TRU waste stored at various facilities on the ORR for eventual off-site disposal at various DOE sitesmore » and commercial facilities. The Remote Handled TRU Waste Sludge held in the Melton Valley Storage Tanks (MVSTs) was produced as a result of the collection, treatment, and storage of liquid radioactive waste originating from the ORNL radiochemical processing and radioisotope production programs. The MVSTs contain most of the associated waste from the Gunite and Associated Tanks (GAAT) in the ORNL's Tank Farms in Bethel Valley and the sludge (SL) and associated waste from the Old Hydro-fracture Facility tanks and other Federal Facility Agreement (FFA) tanks. The SL Processing Facility Build-outs (SL-PFB) Project is integral to the EM cleanup mission at ORNL and is being accelerated by DOE to meet updated regulatory commitments in the Site Treatment Plan. To meet these commitments a Baseline (BL) Change Proposal (BCP) is being submitted to provide continued spending authority as the project re-initiation extends across fiscal year 2012 (FY2012) into fiscal year 2013. Future waste from the ORNL Building 3019 U-233 Disposition project, in the form of U-233 dissolved in nitric acid and water, down-blended with depleted uranyl nitrate solution is also expected to be transferred to the 7856 MVST Annex Facility (formally the Capacity Increase Project (CIP) Tanks) for co-processing with the SL. The SL-PFB project will construct and install the necessary integrated systems to process the accumulated MVST Facilities SL inventory at the TWPC thus enabling safe and effective disposal of the waste. This BCP does not include work to support current MVST Facility Surveillance and Maintenance programs or the ORNL Building 3019 U-233 Disposition project, since they are not currently part of the TWPC prime contract. The purpose of the environmental compliance strategy is to identify the environmental permits and other required regulatory documents necessary for the construction and operation of the SL- PFB at the TWPC, Oak Ridge, TN. The permits and other regulatory documents identified are necessary to comply with the environmental laws and regulations of DOE Orders, and other requirements documented in the SL-PFB, Safety Design Strategy (SDS), SL-A-AD-002, R0 draft, and the Systems, Function and Requirements Document (SFRD), SL-X-AD-002, R1 draft. This compliance strategy is considered a 'living strategy' and it is anticipated that it will be revised as design progresses and more detail is known. The design basis on which this environmental permitting and compliance strategy is based is the Wastren Advantage, Inc., (WAI), TWPC, SL-PFB (WAI-BL-B.01.06) baseline. (authors)« less

Emergence of integrated urology-radiation oncology practices in the State of Texas.

PubMed

Jhaveri, Pavan M; Sun, Zhuyi; Ballas, Leslie; Followill, David S; Hoffman, Karen E; Jiang, Jing; Smith, Benjamin D

2012-09-01

Integrated urology-radiation oncology (RO) practices have been advocated as a means to improve community-based prostate cancer care by joining urologic and radiation care in a single-practice environment. However, little is known regarding the scope and actual physical integration of such practices. We sought to characterize the emergence of such practices in Texas, their extent of physical integration, and their potential effect on patient travel times for radiation therapy. A telephone survey identified integrated urology-RO practices, defined as practices owned by urologists that offer RO services. Geographic information software was used to determine the proximity of integrated urology-RO clinic sites with respect to the state's population. We calculated patient travel time and distance from each integrated urology-RO clinic offering urologic services to the RO treatment facility owned by the integrated practice and to the nearest nonintegrated (independent) RO facility. We compared these times and distances using the Wilcoxon-Mann-Whitney test. Of 229 urology practices identified, 12 (5%) offered integrated RO services, and 182 (28%) of 640 Texas urologists worked in such practices. Approximately 53% of the state population resides within 10 miles of an integrated urology-RO clinic site. Patients with a diagnosis of prostate cancer at an integrated urology-RO clinic site travel a mean of 19.7 miles (26.1 min) from the clinic to reach the RO facility owned by the integrated urology-RO practice vs 5.9 miles (9.2 min) to reach the nearest nonintegrated RO facility (P<.001). Integrated urology-RO practices are common in Texas and are generally clustered in urban areas. In most integrated practices, the urology clinics and the integrated RO facilities are not at the same location, and driving times and distances from the clinic to the integrated RO facility exceed those from the clinic to the nearest nonintegrated RO facility. Copyright © 2012 Elsevier Inc. All rights reserved.

Coal feed component testing for CDIF

NASA Technical Reports Server (NTRS)

Pearson, C. V.; Snyder, B. K.; Fornek, T. E.

1977-01-01

Investigations conducted during the conceptual design of the Montana MHD Component Development and Integration Facility (CDIF) identified commercially available processing and feeding equipment potentially suitable for use in a reference design. Tests on sub-scale units of this equipment indicated that they would perform as intended.

40 CFR 413.04 - Standards for integrated facilities.

Code of Federal Regulations, 2010 CFR

2010-07-01

... GUIDELINES AND STANDARDS ELECTROPLATING POINT SOURCE CATEGORY General Provisions § 413.04 Standards for... § 403.6(e) of EPA's General Pretreatment Regulations. In cases where electroplating process wastewaters... average standard for the electroplating wastewaters must be used. The 30 day average shall be determined...

40 CFR 430.75 - New source performance standards (NSPS).

Code of Federal Regulations, 2010 CFR

2010-07-01

... GUIDELINES AND STANDARDS THE PULP, PAPER, AND PAPERBOARD POINT SOURCE CATEGORY Mechanical Pulp Subcategory § 430.75 New source performance standards (NSPS). (a) The following applies to mechanical pulp...-mechanical process; mechanical pulp facilities where the integrated production of pulp and coarse paper...

Point-of-care testing.

PubMed

O'Brien, J A

2000-12-01

Is POCT worth integrating into a facility? Despite its promise of speed and convenience, this technology requires careful evaluation of potential benefits, disadvantages, and challenges to the existing system. If the pros outweigh the cons, a step-by-step approach can ease the process of implementing a POCT program.

High and Dry

ERIC Educational Resources Information Center

Johnson, Robert L.

2005-01-01

High-performance schools are facilities that improve the learning environment while saving energy, resources and money. Creating a high-performance school requires an integrated design approach. Key systems--including lighting, HVAC, electrical and plumbing--must be considered from the beginning of the design process. According to William H.…

KENNEDY SPACE CENTER, FLA. - The U.S. Node 2 is undergoing a Multi-Element Integrated Test (MEIT) in the Space Station Processing Facility. Node 2 attaches to the end of the U.S. Lab on the ISS and provides attach locations for the Japanese laboratory, European laboratory, the Centrifuge Accommodation Module and, eventually, Multipurpose Logistics Modules. It will provide the primary docking location for the Shuttle when a pressurized mating adapter is attached to Node 2. Installation of the module will complete the U.S. Core of the ISS.

NASA Image and Video Library

2003-08-27

KENNEDY SPACE CENTER, FLA. - The U.S. Node 2 is undergoing a Multi-Element Integrated Test (MEIT) in the Space Station Processing Facility. Node 2 attaches to the end of the U.S. Lab on the ISS and provides attach locations for the Japanese laboratory, European laboratory, the Centrifuge Accommodation Module and, eventually, Multipurpose Logistics Modules. It will provide the primary docking location for the Shuttle when a pressurized mating adapter is attached to Node 2. Installation of the module will complete the U.S. Core of the ISS.

Management support and perceived consumer satisfaction in skilled nursing facilities.

PubMed

Metlen, Scott; Eveleth, Daniel; Bailey, Jeffrey J

2005-08-01

How managers 'manage' employees influences important firm outcomes. Heskett, Sasser, and Schlesinger contend that the level of internal support for service workers will influence consumer satisfaction. This study empirically explores how skilled nursing facility (SNF) managers affect consumer satisfaction by encouraging employee effectiveness and listening to employees to determine how to improve employee effectiveness. We extend previous research by proposing management as a form of internal support and demonstrating its relationship to service process integration, as a distinct form of internal support. The results of our individual-level investigation of 630 nursing assistants from 45 SNFs provide support for our two-part hypothesis. First, active management support and process integration, as elements of internal support, do lead to increased employee satisfaction and employee effectiveness. Second, the increased employee satisfaction and effectiveness was positively related to consumer satisfaction, as evaluated by the service workers. Thus, there is a positive influence of management's internal support of nursing assistants on perceived consumer satisfaction.

Payload/GSE/data system interface: Users guide for the VPF (Vertical Processing Facility)

NASA Technical Reports Server (NTRS)

1993-01-01

Payload/GSE/data system interface users guide for the Vertical Processing Facility is presented. The purpose of the document is three fold. First, the simulated Payload and Ground Support Equipment (GSE) Data System Interface, which is also known as the payload T-0 (T-Zero) System is described. This simulated system is located with the Cargo Integration Test Equipment (CITE) in the Vertical Processing Facility (VPF) that is located in the KSC Industrial Area. The actual Payload T-0 System consists of the Orbiter, Mobile Launch Platforms (MLPs), and Launch Complex (LC) 39A and B. This is referred to as the Pad Payload T-0 System (Refer to KSC-DL-116 for Pad Payload T-0 System description). Secondly, information is provided to the payload customer of differences between this simulated system and the actual system. Thirdly, a reference guide of the VPF Payload T-0 System for both KSC and payload customer personnel is provided.

Supervisory Control and Data Acquisition System | Energy Systems

Science.gov Websites

Integration Facility | NREL Supervisory Control and Data Acquisition System Supervisory Control supervisory control and data acquisition (SCADA) system monitors and controls safety systems and gathers real Energy Systems Integration Facility control room. The Energy Systems Integration Facility's SCADA system

Energy Systems Integration Facility Overview

ScienceCinema

Arvizu, Dan; Chistensen, Dana; Hannegan, Bryan; Garret, Bobi; Kroposki, Ben; Symko-Davies, Martha; Post, David; Hammond, Steve; Kutscher, Chuck; Wipke, Keith

2018-01-16

The U.S. Department of Energy's Energy Systems Integration Facility (ESIF) is located at the National Renewable Energy Laboratory is the right tool, at the right time... a first-of-its-kind facility that addresses the challenges of large-scale integration of clean energy technologies into the energy systems that power the nation.

Space station automation study: Automation requirements derived from space manufacturing concepts. Volume 1: Executive summary

NASA Technical Reports Server (NTRS)

1984-01-01

The electroepitaxial process and the Very Large Scale Integration (VLSI) circuits (chips) facilities were chosen because each requires a very high degree of automation, and therefore involved extensive use of teleoperators, robotics, process mechanization, and artificial intelligence. Both cover a raw materials process and a sophisticated multi-step process and are therfore highly representative of the kinds of difficult operation, maintenance, and repair challenges which can be expected for any type of space manufacturing facility. Generic areas were identified which will require significant further study. The initial design will be based on terrestrial state-of-the-art hard automation. One hundred candidate missions were evaluated on the basis of automation portential and availability of meaning ful knowldege. The design requirements and unconstrained design concepts developed for the two missions are presented.

KSC-06pd1204

NASA Image and Video Library

2006-06-23

KENNEDY SPACE CENTER, FLA. - An overview of the new Firing Room 4 shows the expanse of computer stations and the various operations the facility will be able to manage. FR4 is now designated the primary firing room for all remaining shuttle launches, and will also be used daily to manage operations in the Orbiter Processing Facilities and for integrated processing for the shuttle. The firing room now includes sound-suppressing walls and floors, new humidity control, fire-suppression systems and consoles, support tables with computer stations, communication systems and laptop computer ports. FR 4 also has power and computer network connections and a newly improved Checkout, Control and Monitor Subsystem. The renovation is part of the Launch Processing System Extended Survivability Project that began in 2003. United Space Alliance's Launch Processing System directorate managed the FR 4 project for NASA. Photo credit: NASA/Dimitri Gerondidakis

Simulation technology - A key to effective man-machine integration for future combat rotorcraft systems

NASA Technical Reports Server (NTRS)

Kerr, Andrew W.

1990-01-01

The utilization of advanced simulation technology in the development of the non-real-time MANPRINT design tools in the Army/NASA Aircrew-Aircraft Integration (A3I) program is described. A description is then given of the Crew Station Research and Development Facilities, the primary tool for the application of MANPRINT principles. The purpose of the A3I program is to develop a rational, predictive methodology for helicopter cockpit system design that integrates human factors engineering with other principles at an early stage in the development process, avoiding the high cost of previous system design methods. Enabling technologies such as the MIDAS work station are examined, and the potential of low-cost parallel-processing systems is indicated.

Emergence of Integrated Urology-Radiation Oncology Practices in the State of Texas

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jhaveri, Pavan M.; Sun Zhuyi; Ballas, Leslie

2012-09-01

Purpose: Integrated urology-radiation oncology (RO) practices have been advocated as a means to improve community-based prostate cancer care by joining urologic and radiation care in a single-practice environment. However, little is known regarding the scope and actual physical integration of such practices. We sought to characterize the emergence of such practices in Texas, their extent of physical integration, and their potential effect on patient travel times for radiation therapy. Methods and Materials: A telephone survey identified integrated urology-RO practices, defined as practices owned by urologists that offer RO services. Geographic information software was used to determine the proximity of integratedmore » urology-RO clinic sites with respect to the state's population. We calculated patient travel time and distance from each integrated urology-RO clinic offering urologic services to the RO treatment facility owned by the integrated practice and to the nearest nonintegrated (independent) RO facility. We compared these times and distances using the Wilcoxon-Mann-Whitney test. Results: Of 229 urology practices identified, 12 (5%) offered integrated RO services, and 182 (28%) of 640 Texas urologists worked in such practices. Approximately 53% of the state population resides within 10 miles of an integrated urology-RO clinic site. Patients with a diagnosis of prostate cancer at an integrated urology-RO clinic site travel a mean of 19.7 miles (26.1 min) from the clinic to reach the RO facility owned by the integrated urology-RO practice vs 5.9 miles (9.2 min) to reach the nearest nonintegrated RO facility (P<.001). Conclusions: Integrated urology-RO practices are common in Texas and are generally clustered in urban areas. In most integrated practices, the urology clinics and the integrated RO facilities are not at the same location, and driving times and distances from the clinic to the integrated RO facility exceed those from the clinic to the nearest nonintegrated RO facility.« less

Collaborative Mission Design at NASA Langley Research Center

NASA Technical Reports Server (NTRS)

Gough, Kerry M.; Allen, B. Danette; Amundsen, Ruth M.

2005-01-01

NASA Langley Research Center (LaRC) has developed and tested two facilities dedicated to increasing efficiency in key mission design processes, including payload design, mission planning, and implementation plan development, among others. The Integrated Design Center (IDC) is a state-of-the-art concurrent design facility which allows scientists and spaceflight engineers to produce project designs and mission plans in a real-time collaborative environment, using industry-standard physics-based development tools and the latest communication technology. The Mission Simulation Lab (MiSL), a virtual reality (VR) facility focused on payload and project design, permits engineers to quickly translate their design and modeling output into enhanced three-dimensional models and then examine them in a realistic full-scale virtual environment. The authors were responsible for envisioning both facilities and turning those visions into fully operational mission design resources at LaRC with multiple advanced capabilities and applications. In addition, the authors have created a synergistic interface between these two facilities. This combined functionality is the Interactive Design and Simulation Center (IDSC), a meta-facility which offers project teams a powerful array of highly advanced tools, permitting them to rapidly produce project designs while maintaining the integrity of the input from every discipline expert on the project. The concept-to-flight mission support provided by IDSC has shown improved inter- and intra-team communication and a reduction in the resources required for proposal development, requirements definition, and design effort.

KSC-97PC1761

NASA Image and Video Library

1997-12-10

United States Senator Bob Graham of Florida visits the Space Station Processing Facility at Kennedy Space Center (KSC) and is briefed on hardware processing for the International Space Station by Jon Cowart, Flight 2A Manager, NASA Space Station Hardware Integration Office. In the foreground, from left to right, are Howard DeCastro, Program Manager for the Space Flight Operations Contract, United Space Alliance; Senator Bob Graham; and Jon Cowart

Naval electronic warfare simulation for effectiveness assessment and softkill programmability facility

NASA Astrophysics Data System (ADS)

Lançon, F.

2011-06-01

The Anti-ship Missile (ASM) threat to be faced by ships will become more diverse and difficult. Intelligence, rules of engagement constraints, fast reaction-time for effective softkill solution require specific tools to design Electronic Warfare (EW) systems and to integrate it onboard ship. SAGEM Company provides decoy launcher system [1] and its associated Naval Electronic Warfare Simulation tool (NEWS) to permit softkill effectiveness analysis for anti-ship missile defence. NEWS tool generates virtual environment for missile-ship engagement and counter-measure simulator over a wide spectrum: RF, IR, EO. It integrates EW Command & Control (EWC2) process which is implemented in decoy launcher system and performs Monte-Carlo batch processing to evaluate softkill effectiveness in different engagement situations. NEWS is designed to allow immediate EWC2 process integration from simulation to real decoy launcher system. By design, it allows the final operator to be able to program, test and integrate its own EWC2 module and EW library onboard, so intelligence of each user is protected and evolution of threat can be taken into account through EW library update. The objectives of NEWS tool are also to define a methodology for trial definition and trial data reduction. Growth potential would permit to design new concept for EWC2 programmability and real time effectiveness estimation in EW system. This tool can also be used for operator training purpose. This paper presents the architecture design, the softkill programmability facility concept and the flexibility for onboard integration on ship. The concept of this operationally focused simulation, which is to use only one tool for design, development, trial validation and operational use, will be demonstrated.

Lessons Learned from the 200 West Pump and Treatment Facility Construction Project at the US DOE Hanford Site - A Leadership for Energy and Environmental Design (LEED) Gold-Certified Facility - 13113

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dorr, Kent A.; Freeman-Pollard, Jhivaun R.; Ostrom, Michael J.

CH2M Hill Plateau Remediation Company (CHPRC) designed, constructed, commissioned, and began operation of the largest groundwater pump and treatment facility in the U.S. Department of Energy's (DOE) nationwide complex. This one-of-a-kind groundwater pump and treatment facility, located at the Hanford Nuclear Reservation Site (Hanford Site) in Washington State, was built to an accelerated schedule with American Recovery and Reinvestment Act (ARRA) funds. There were many contractual, technical, configuration management, quality, safety, and Leadership in Energy and Environmental Design (LEED) challenges associated with the design, procurement, construction, and commissioning of this $95 million, 52,000 ft groundwater pump and treatment facility tomore » meet DOE's mission objective of treating contaminated groundwater at the Hanford Site with a new facility by June 28, 2012. The project team's successful integration of the project's core values and green energy technology throughout design, procurement, construction, and start-up of this complex, first-of-its-kind Bio Process facility resulted in successful achievement of DOE's mission objective, as well as attainment of LEED GOLD certification (Figure 1), which makes this Bio Process facility the first non-administrative building in the DOE Office of Environmental Management complex to earn such an award. (authors)« less

Design and optimization of integrated gas/condensate plants

DOE Office of Scientific and Technical Information (OSTI.GOV)

Root, C.R.; Wilson, J.L.

1995-11-01

An optimized design is demonstrated for combining gas processing and condensate stabilization plants into a single integrated process facility. This integrated design economically provides improved condensate recovery versus use of a simple stabilizer design. A selection matrix showing likely application of this integrated process is presented for use on future designs. Several methods for developing the fluid characterization and for using a process simulator to predict future design compositions are described, which could be useful in other designs. Optimization of flowsheet equipment choices and of design operating pressures and temperatures is demonstrated including the effect of both continuous and discretemore » process equipment size changes. Several similar designs using a turboexpander to provide refrigeration for liquids recovery and stabilizer reflux are described. Operating overthrust and from the P/15-D platform in the Dutch sector of the North Sea has proven these integrated designs are effective. Concerns do remain around operation near or above the critical pressure that should be addressed in future work including providing conservative separator designs, providing sufficient process design safety margin to meet dew point specifications, selecting the most conservative design values of predicted gas dew point and equipment size calculated with different Equations-of-State, and possibly improving the accuracy of PVT calculations in the near critical area.« less

About Distributed Simulation-based Optimization of Forming Processes using a Grid Architecture

NASA Astrophysics Data System (ADS)

Grauer, Manfred; Barth, Thomas

2004-06-01

Permanently increasing complexity of products and their manufacturing processes combined with a shorter "time-to-market" leads to more and more use of simulation and optimization software systems for product design. Finding a "good" design of a product implies the solution of computationally expensive optimization problems based on the results of simulation. Due to the computational load caused by the solution of these problems, the requirements on the Information&Telecommunication (IT) infrastructure of an enterprise or research facility are shifting from stand-alone resources towards the integration of software and hardware resources in a distributed environment for high-performance computing. Resources can either comprise software systems, hardware systems, or communication networks. An appropriate IT-infrastructure must provide the means to integrate all these resources and enable their use even across a network to cope with requirements from geographically distributed scenarios, e.g. in computational engineering and/or collaborative engineering. Integrating expert's knowledge into the optimization process is inevitable in order to reduce the complexity caused by the number of design variables and the high dimensionality of the design space. Hence, utilization of knowledge-based systems must be supported by providing data management facilities as a basis for knowledge extraction from product data. In this paper, the focus is put on a distributed problem solving environment (PSE) capable of providing access to a variety of necessary resources and services. A distributed approach integrating simulation and optimization on a network of workstations and cluster systems is presented. For geometry generation the CAD-system CATIA is used which is coupled with the FEM-simulation system INDEED for simulation of sheet-metal forming processes and the problem solving environment OpTiX for distributed optimization.

Ethiopia's assessment of emergency obstetric and newborn care: setting the gold standard for national facility-based assessments.

PubMed

Keyes, Emily B; Haile-Mariam, Abonesh; Belayneh, Neghist T; Gobezie, Wasihun A; Pearson, Luwei; Abdullah, Muna; Kebede, Henok

2011-10-01

To describe the methods used to implement Ethiopia's 2008 emergency obstetric and newborn care services (EmONC) assessment; highlight how the collaborative process contributed to immediate integration of results into national and subnational planning; and explain how the experience informed the development of a set of tools providing best practices and guidelines for other countries conducting similar assessments. A team of maternal and newborn health experts from the Federal Ministry of Health (FMOH), the United Nations Children's Fund (UNICEF), the World Health Organization (WHO), and the United Nations Population Fund (UNFPA), together with representatives from the Ethiopian Society of Obstetricians and Gynecologists, provided technical guidance for the 18-month process and facilitated demand for and use of the assessment results. Eighty-four trained data collectors administered 9 data collection modules in 806 public and private facilities. Field work and data were managed by a private firm who, together with the core team, implemented a multi-layered plan for data quality. Columbia University's Averting Maternal Death and Disability Program provided technical assistance. Results were published in national and regional reports and in 1-page facility factsheets informing subnational planning activities. Assessment results-which have been published in journal articles-informed water infrastructure improvements, efforts to expand access to magnesium sulfate, and FMOH and UN planning documents. The assessment also established a permanent database for future monitoring of the health system, including geographic locations of surveyed facilities. Ethiopia's assessment was successful largely because of active local leadership, a collaborative process, ample financial and technical support, and rapid integration of results into health system planning. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

17 CFR 250.58 - Exemption of investments in certain nonutility companies.

Code of Federal Regulations, 2010 CFR

2010-04-01

... facilities relating to electric and compressed natural gas powered vehicles; (iv) The sale of electric and gas appliances; equipment to promote new technologies, or new applications for existing technologies... and commercialization of technologies or processes that utilize coal waste by-products as an integral...

Energy Systems Fabrication Laboratory | Energy Systems Integration Facility

Science.gov Websites

Fabrication The fuel cell fabrication hub includes laboratory spaces with local exhaust and chemical fume hoods that support electrolysis and other chemical process research. Key Infrastructure Perchloric acid washdown hood, local exhaust, specialty gas manifolding, deionized water, chemical fume hoods, glassware

Orion EM-1 Interim Cryogenic Propulsion Stage (ICPS) move from HIF to DOC

NASA Image and Video Library

2017-04-12

The Orion EM-1 Interim Cryogenic Propulsion Stage is moved from the Horizontal Integration Facility (HIF) to the Delta Operations Center (DOC) at Cape Canaveral Air Force Station to continue processing for it's future mission on the Space Launch System rocket.

40 CFR 430.77 - Pretreatment standards for new sources (PSNS).

Code of Federal Regulations, 2010 CFR

2010-07-01

...) EFFLUENT GUIDELINES AND STANDARDS THE PULP, PAPER, AND PAPERBOARD POINT SOURCE CATEGORY Mechanical Pulp Subcategory § 430.77 Pretreatment standards for new sources (PSNS). (a) The following applies to mechanical... thermo-mechanical process; mechanical pulp facilities where the integrated production of pulp and coarse...

40 CFR 98.267 - Records that must be retained.

Code of Federal Regulations, 2014 CFR

2014-07-01

... (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Phosphoric Acid Production § 98.267 Records that must be... paragraphs (a) through (c) of this section for each wet-process phosphoric acid production facility. (a.../or deliveries (if vertically integrated with a mine). (c) Documentation of the procedures used to...

Afghanistan: Narcotics and U.S. Policy

DTIC Science & Technology

2007-09-14

programs to develop integrated systems of crop processing facilities, storage areas, roads, and markets, and to restore wheat and other cereal crop...London), May 26, 2002; Antony Barnett, “UK in Secret Biological War on Drugs,” Observer (London), September 17, 2000; Juanita Darling, “ Fungi May Be

KSC-2009-2320

NASA Image and Video Library

2009-03-26

CAPE CANAVERAL, Fla. – In the Rotation, Processing and Surge Facility at NASA's Kennedy Space Center in Florida, technicians check the fit of the end cover on the Ares I-X motor segment. It is one of four reusable motor segments and nozzle exit cone shipped by the Ares I first-stage prime contractor Alliant Techsystems Inc. for final processing and integration in the facility. The booster used for the Ares I-X launch is being modified by adding new forward structures and a fifth segment simulator. The motor is the final hardware needed for the rocket's upcoming flight test this summer. The stacking operations are scheduled to begin in the Vehicle Assembly Building in April. Photo credit: NASA/Jim Grossmann

KSC-2009-2321

NASA Image and Video Library

2009-03-26

CAPE CANAVERAL, Fla. – In the Rotation, Processing and Surge Facility at NASA's Kennedy Space Center in Florida, the open end of the Ares I-X motor segment is seen without the end cover. It is one of four reusable motor segments and nozzle exit cone shipped by the Ares I first-stage prime contractor Alliant Techsystems Inc. for final processing and integration in the facility. The booster used for the Ares I-X launch is being modified by adding new forward structures and a fifth segment simulator. The motor is the final hardware needed for the rocket's upcoming flight test this summer. The stacking operations are scheduled to begin in the Vehicle Assembly Building in April. Photo credit: NASA/Jim Grossmann

KSC-2009-2319

NASA Image and Video Library

2009-03-26

CAPE CANAVERAL, Fla. – In the Rotation, Processing and Surge Facility at NASA's Kennedy Space Center in Florida, a technician begins propellant grain inspection of the interior of the Ares I-X motor segment. It is one of four reusable motor segments and nozzle exit cone shipped by the Ares I first-stage prime contractor Alliant Techsystems Inc. for final processing and integration in the facility. The booster used for the Ares I-X launch is being modified by adding new forward structures and a fifth segment simulator. The motor is the final hardware needed for the rocket's upcoming flight test this summer. The stacking operations are scheduled to begin in the Vehicle Assembly Building in April. Photo credit: NASA/Jim Grossmann

KSC-2009-2316

NASA Image and Video Library

2009-03-26

CAPE CANAVERAL, Fla. – In the Rotation, Processing and Surge Facility at NASA's Kennedy Space Center in Florida, the Ares I-X motor segment waits for inspection after removal of the shipping container. It is one of four reusable motor segments and nozzle exit cone shipped by the Ares I first-stage prime contractor Alliant Techsystems Inc. for final processing and integration in the facility. The booster used for the Ares I-X launch is being modified by adding new forward structures and a fifth segment simulator. The motor is the final hardware needed for the rocket's upcoming flight test this summer. The stacking operations are scheduled to begin in the Vehicle Assembly Building in April. Photo credit: NASA/Jim Grossmann

KSC-2009-2322

NASA Image and Video Library

2009-03-26

CAPE CANAVERAL, Fla. – In the Rotation, Processing and Surge Facility at NASA's Kennedy Space Center in Florida, a technician performs propellant grain inspection of the inside of the Ares I-X motor segment. It is one of four reusable motor segments and nozzle exit cone shipped by the Ares I first-stage prime contractor Alliant Techsystems Inc. for final processing and integration in the facility. The booster used for the Ares I-X launch is being modified by adding new forward structures and a fifth segment simulator. The motor is the final hardware needed for the rocket's upcoming flight test this summer. The stacking operations are scheduled to begin in the Vehicle Assembly Building in April. Photo credit: NASA/Jim Grossmann

KSC-2009-2314

NASA Image and Video Library

2009-03-26

CAPE CANAVERAL, Fla. – In the Rotation, Processing and Surge Facility at NASA's Kennedy Space Center in Florida, the rail car cover is moved away from the first Ares I-X motor segment. It is one of four reusable motor segments and nozzle exit cone shipped by the Ares I first-stage prime contractor Alliant Techsystems Inc. for final processing and integration in the facility. The booster used for the Ares I-X launch is being modified by adding new forward structures and a fifth segment simulator. The motor is the final hardware needed for the rocket's upcoming flight test this summer. The stacking operations are scheduled to begin in the Vehicle Assembly Building in April. Photo credit: NASA/Jim Grossmann

KSC-2009-2315

NASA Image and Video Library

2009-03-26

CAPE CANAVERAL, Fla. – In the Rotation, Processing and Surge Facility at NASA's Kennedy Space Center in Florida, the Ares I-X motor segment is revealed after removal of the rail car cover. It is one of four reusable motor segments and nozzle exit cone shipped by the Ares I first-stage prime contractor Alliant Techsystems Inc. for final processing and integration in the facility. The booster used for the Ares I-X launch is being modified by adding new forward structures and a fifth segment simulator. The motor is the final hardware needed for the rocket's upcoming flight test this summer. The stacking operations are scheduled to begin in the Vehicle Assembly Building in April. Photo credit: NASA/Jim Grossmann

KSC-2009-2313

NASA Image and Video Library

2009-03-26

CAPE CANAVERAL, Fla. – In the Rotation, Processing and Surge Facility at NASA's Kennedy Space Center in Florida, the rail car cover is removed from the first Ares I-X motor segment. It is one of four reusable motor segments and nozzle exit cone shipped by the Ares I first-stage prime contractor Alliant Techsystems Inc. for final processing and integration in the facility. The booster used for the Ares I-X launch is being modified by adding new forward structures and a fifth segment simulator. The motor is the final hardware needed for the rocket's upcoming flight test this summer. The stacking operations are scheduled to begin in the Vehicle Assembly Building in April. Photo credit: NASA/Jim Grossmann

KSC-2009-2312

NASA Image and Video Library

2009-03-26

CAPE CANAVERAL, Fla. – In the Rotation, Processing and Surge Facility at NASA's Kennedy Space Center in Florida, the rail car cover is removed from the first Ares I-X motor segment. It is one of four reusable motor segments and nozzle exit cone shipped by the Ares I first-stage prime contractor Alliant Techsystems Inc. for final processing and integration in the facility. The booster used for the Ares I-X launch is being modified by adding new forward structures and a fifth segment simulator. The motor is the final hardware needed for the rocket's upcoming flight test this summer. The stacking operations are scheduled to begin in the Vehicle Assembly Building in April. Photo credit: NASA/Jim Grossmann

Materials International Space Station Experiment (MISSE) Arrival

NASA Image and Video Library

2017-10-02

The Materials International Space Station Experiment-Flight Facility, or MISSE-FF, hardware arrived at the Space Station Processing Facility low bay at NASA's Kennedy Space Center in Florida. MISSE will be unpacked for integration and processing. MISSE will be used to test various materials and computing elements on the exterior of the space station. They will be exposed to the harsh environment of low-Earth orbit, including to a vacuum, atomic oxygen, ultraviolet radiation, direct sunlight and extreme heat and cold. The experiment will provide a better understanding of material durability, from coatings to electronic sensors, which could be applied to future spacecraft designs. MISSE will be delivered to the space station on a future commercial resupply mission.

KSC-2009-2308

NASA Image and Video Library

2009-03-26

CAPE CANAVERAL, Fla. – The NASA Railroad hauls one of the cars with the first Ares I-X segment to the Rotation, Processing and Surge Facility at NASA's Kennedy Space Center in Florida. Four reusable motor segments and the nozzle exit cone, manufactured by the Ares I first-stage prime contractor Alliant Techsystems Inc., departed Utah March 12 on the seven-day, cross-country trip to Florida. The segments are being delivered to Kennedy's Rotation, Processing and Surge Facility for final processing and integration. The booster used for the Ares I-X launch is being modified by adding new forward structures and a fifth segment simulator. The motor is the final hardware needed for the rocket's upcoming test flight this summer. The stacking operations are scheduled to begin in the Vehicle Assembly Building in April. Photo credit: NASA/Jack Pfaller

KSC-2009-2307

NASA Image and Video Library

2009-03-26

CAPE CANAVERAL, Fla. – The NASA Railroad hauls one of the cars with the first Ares I-X segment to the Rotation, Processing and Surge Facility at NASA's Kennedy Space Center in Florida. Four reusable motor segments and the nozzle exit cone, manufactured by the Ares I first-stage prime contractor Alliant Techsystems Inc., departed Utah March 12 on the seven-day, cross-country trip to Florida. The segments are being delivered to Kennedy's Rotation, Processing and Surge Facility for final processing and integration. The booster used for the Ares I-X launch is being modified by adding new forward structures and a fifth segment simulator. The motor is the final hardware needed for the rocket's upcoming test flight this summer. The stacking operations are scheduled to begin in the Vehicle Assembly Building in April. Photo credit: NASA/Jack Pfaller

KSC-2009-2310

NASA Image and Video Library

2009-03-26

CAPE CANAVERAL, Fla. – The NASA Railroad delivers the first Ares I-X segment to the Rotation, Processing and Surge Facility at NASA's Kennedy Space Center in Florida. Four reusable motor segments and the nozzle exit cone, manufactured by the Ares I first-stage prime contractor Alliant Techsystems Inc., departed Utah March 12 on the seven-day, cross-country trip to Florida. The segments are being delivered to Kennedy's Rotation, Processing and Surge Facility for final processing and integration. The booster used for the Ares I-X launch is being modified by adding new forward structures and a fifth segment simulator. The motor is the final hardware needed for the rocket's upcoming test flight this summer. The stacking operations are scheduled to begin in the Vehicle Assembly Building in April. Photo credit: NASA/Jack Pfaller

KSC-2009-2309

NASA Image and Video Library

2009-03-26

CAPE CANAVERAL, Fla. – The NASA Railroad delivers the first Ares I-X segment to the Rotation, Processing and Surge Facility at NASA's Kennedy Space Center in Florida. Four reusable motor segments and the nozzle exit cone, manufactured by the Ares I first-stage prime contractor Alliant Techsystems Inc., departed Utah March 12 on the seven-day, cross-country trip to Florida. The segments are being delivered to Kennedy's Rotation, Processing and Surge Facility for final processing and integration. The booster used for the Ares I-X launch is being modified by adding new forward structures and a fifth segment simulator. The motor is the final hardware needed for the rocket's upcoming test flight this summer. The stacking operations are scheduled to begin in the Vehicle Assembly Building in April. Photo credit: NASA/Jack Pfaller

Characterization of the animal by-product meal industry in Costa Rica: Manufacturing practices through the production chain and food safety

PubMed Central

Leiva, A; Granados-Chinchilla, F; Redondo-Solano, M; Arrieta-González, M; Pineda-Salazar, E; Molina, A

2018-01-01

ABSTRACT Animal by-product rendering establishments are still relevant industries worldwide. Animal by-product meal safety is paramount to protect feed, animals, and the rest of the food chain from unwanted contamination. As microbiological contamination may arise from inadequate processing of slaughterhouse waste and deficiencies in good manufacturing practices within the rendering facilities, we conducted an overall establishment's inspection, including the product in several parts of the process. An evaluation of the Good Manufacturing Practices (GMP) was carried out, which included the location and access (i.e., admission) to the facilities, integrated pest management programs, physical condition of the facilities (e.g., infrastructure), equipments, vehicles and transportation, as well as critical control points (i.e., particle size and temperature set at 50 mm, 133°C at atmospheric pressure for 20 min, respectively) recommended by the OIE and the European Commission. The most sensitive points according to the evaluation are physical structure of the facilities (avg 42.2%), access to the facilities (avg 48.6%), and cleaning procedures (avg 51.4%). Also, indicator microorganisms (Salmonella spp., Clostridium spp., total coliforms, E. coli, E. coli O157:H7) were used to evaluate the safety in different parts of the animal meal production process. There was a prevalence of Salmonella spp. of 12.9, 14.3, and 33.3% in Meat and Bone Meal (MBM), poultry by-products, and fish meal, respectively. However, there were no significant differences (P = 0.73) in the prevalence between the different animal meals, according to the data collected. It was also observed that renderings associated with the poultry industry (i.e., 92.0%) obtained the best ratings overall, which reflects a satisfactory development of this sector and the integration of its production system as a whole. PMID:29562297

A high resolution PVDF (peizoelectric) film respiration sensor

NASA Astrophysics Data System (ADS)

Nakano, Katsuya; Fujita, Kento; Misaki, Shinya; Fujii, Hiroyuki; Johnston, Robert; Misaki, Yukinori

2017-07-01

Sensors used today for contact measurement of a subject's breathing work by measuring the inductance change in some film, piezoelectric or pyro-electric, used in the sensor. However, their use can increase stress and burden for patients because of the close proximity to the body that the sensors must be to operate. They must be applied directly to the patient's body by tape or adhesive paste. To address this problem and reduce subject stress and burden, it was decided to research development of a high resolution breathing sensor that could still function even while placed over the patient's clothes. This was achieved by developing a new PVDF piezoelectric film based sensor with an innovative configuration. Through the use of some simple amplification circuitry and processing the output signal, the high sensitivity breathing sensor developed was determined to be able to accurately measure a person's breathing. Also, due to the high sensitivity of the sensor, heart rate was also detectable revealing the possibility for simultaneous measurement of both breathing and heart rate.

Robotic end-effector for rewaterproofing shuttle tiles

NASA Astrophysics Data System (ADS)

Manouchehri, Davoud; Hansen, Joseph M.; Wu, Cheng M.; Yamamoto, Brian S.; Graham, Todd

1992-11-01

This paper summarizes work by Rockwell International's Space Systems Division's Robotics Group at Downey, California. The work is part of a NASA-led team effort to automate Space Shuttle rewaterproofing in the Orbiter Processing Facility at the Kennedy Space Center and the ferry facility at the Ames-Dryden Flight Research Facility. Rockwell's effort focuses on the rewaterproofing end-effector, whose function is to inject hazardous dimethylethyloxysilane into thousands of ceramic tiles on the underside of the orbiter after each flight. The paper has five sections. First, it presents background on the present manual process. Second, end-effector requirements are presented, including safety and interface control. Third, a design is presented for the five end-effector systems: positioning, delivery, containment, data management, and command and control. Fourth, end-effector testing and integrating to the total system are described. Lastly, future applications for this technology are discussed.

ICIASF '85 - International Congress on Instrumentation in Aerospace Simulation Facilities, 11th, Stanford University, CA, August 26-28, 1985, Record

NASA Technical Reports Server (NTRS)

1985-01-01

Developments related to laser Doppler velocimetry are discussed, taking into account a three-component dual beam laser-Doppler-anemometer to be operated in large wind tunnels, a new optical system for three-dimensional laser-Doppler-anemometry using an argon-ion and a dye laser, and a two-component laser Doppler velocimeter by switching fringe orientation. Other topics studied are concerned with facilities, instrumentation, control, hot wire/thin film measurements, optical diagnostic techniques, signal and data processing, facilities and adaptive wall test sections, data acquisition and processing, ballistic instrument systems, dynamic testing and material deformation measurements, optical flow measurements, test techniques, force measurement systems, and holography. Attention is given to nonlinear calibration of integral wind tunnel balances, a microcomputer system for real time digitized image compression, and two phase flow diagnostics in propulsion systems.

Safeguards in Pyroprocessing: an Integrated Model Development and Measurement Data Analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Jinsuo

Pyroprocessing is an electrochemical method based on the molten salt electrolyte, mainly the LiCl-KCl eutectic molten salt, to recycle the used nuclear fuel. For a conceptual design of commercial pyroprocessing facility, tons of special nuclear materials, namely U and Pu, may be involved, which could be used for non-peaceful purposes if they are diverted. Effective safeguards approaches have to be developed prior to the development and construction of a pyroprocessing facility. Present research focused on two main objectives, namely calculating the properties of nuclear species in LiCl-KCl molten salt and developing integrated model to safeguard a pyroprocessing facility. Understanding themore » characteristics of special nuclear materials in LiCl-KCl eutectic salt is extremely important to understand their behaviors in an electrorefiner. The model development for the separation processes in the pyroprocessing, including electrorefining, actinide drawdown, and rare earth drawdown benefits the understanding of material transport and separation performance of these processes under various conditions. The output signals, such as potential, current, and species concentration contribute to the material balance closure and provide safeguards signatures to detect the scenarios of diversion. U and Pu are the two main elements concerned in this study due to our interest in safeguards.« less

Compatibility analysis of material and energy recovery in a regional solid waste management system.

PubMed

Chang, Ying-Hsi; Chang, Ni-Bin

2003-01-01

The rising prices of raw materials and concerns about energy conservation have resulted in an increasing interest in the simultaneous recovery of materials and energy from waste streams. Compatibility exists for several economic, environmental, and managerial reasons. Installing an on-site or off-site presorting facility before an incinerator could be a feasible alternative to achieve both goals if household recycling programs cannot succeed in local communities. However, the regional impacts of presorting solid waste on a waste-to-energy facility remain unclear because of the inherent complexity of solid waste compositions and properties over different areas. This paper applies a system-based approach to assess the impact of installing a refuse-derived fuel (RDF) process before an incinerator. Such an RDF process, consisting of standard unit operations of shredding, magnetic separation, trommel screening, and air classification, might be useful for integrating the recycling and presorting efforts for a large-scale municipal incinerator from a regional sense. An optimization modeling analysis is performed to characterize such integration potential so that the optimal size of the RDF process and associated shipping patterns for flow control can be foreseen. It aims at exploring how the waste inflows with different rates of generation, physical and chemical compositions, and heating values collected from differing administrative districts can be processed by either a centralized presorting facility or an incinerator to meet both the energy recovery and throughput requirements. A case study conducted in Taipei County, which is one of the most densely populated metropolitan areas in Taiwan, further confirms the application potential of such a cost-benefit analysis.

Compact plasma Pockels cell for TIL of SGIII laser facility

NASA Astrophysics Data System (ADS)

Zhang, Xiongjun; Wu, Dengsheng; Lin, Doughui; Yu, Haiwu; Zhang, Jun

2008-01-01

Compact plasma Pockel's cells (PPC) with 70mm aperture driven by one-pulse process have been constructed for technical integration line (TIL) of SGIII laser facility. The experimental results indicate that the working range of gas pressure is wide, and the delay of gas breakdown is steady. Measurements of the optical performance show static transmittance of 93.1%, static extinction ratio of 3900, and average switching efficiency of 99.7%. Eight compact PPCs are used for the second-stage integrating experiments of TIL. By using of parallel driving technology, one driver can work for four PPCs. An analyzer of optical switch is replaced with Brewster-angle Nd-glass slabs in amplifier. Two years application results show that the PPCs can effectively minimize the growth of parasitic-oscillation, and have a high reliability.

Facility and Laboratory Equipment | Energy Systems Integration Facility |

Science.gov Websites

Energy Systems Integration Facility is its infrastructure. In addition to extensive fixed laboratory . Photo of researchers testing building loads and power networks in the Systems Performance Laboratory

Assessment of Space Nuclear Thermal Propulsion Facility and Capability Needs

DOE Office of Scientific and Technical Information (OSTI.GOV)

James Werner

The development of a Nuclear Thermal Propulsion (NTP) system rests heavily upon being able to fabricate and demonstrate the performance of a high temperature nuclear fuel as well as demonstrating an integrated system prior to launch. A number of studies have been performed in the past which identified the facilities needed and the capabilities available to meet the needs and requirements identified at that time. Since that time, many facilities and capabilities within the Department of Energy have been removed or decommissioned. This paper provides a brief overview of the anticipated facility needs and identifies some promising concepts to bemore » considered which could support the development of a nuclear thermal propulsion system. Detailed trade studies will need to be performed to support the decision making process.« less

Space Station Environmental Control and Life Support System Test Facility at Marshall Space Flight Center

NASA Technical Reports Server (NTRS)

Springer, Darlene

1989-01-01

Different aspects of Space Station Environmental Control and Life Support System (ECLSS) testing are currently taking place at Marshall Space Flight Center (MSFC). Unique to this testing is the variety of test areas and the fact that all are located in one building. The north high bay of building 4755, the Core Module Integration Facility (CMIF), contains the following test areas: the Subsystem Test Area, the Comparative Test Area, the Process Material Management System (PMMS), the Core Module Simulator (CMS), the End-use Equipment Facility (EEF), and the Pre-development Operational System Test (POST) Area. This paper addresses the facility that supports these test areas and briefly describes the testing in each area. Future plans for the building and Space Station module configurations will also be discussed.

Dry syngas purification process for coal gas produced in oxy-fuel type integrated gasification combined cycle power generation with carbon dioxide capturing feature.

PubMed

Kobayashi, Makoto; Akiho, Hiroyuki

2017-12-01

Electricity production from coal fuel with minimizing efficiency penalty for the carbon dioxide abatement will bring us sustainable and compatible energy utilization. One of the promising options is oxy-fuel type Integrated Gasification Combined Cycle (oxy-fuel IGCC) power generation that is estimated to achieve thermal efficiency of 44% at lower heating value (LHV) base and provide compressed carbon dioxide (CO 2 ) with concentration of 93 vol%. The proper operation of the plant is established by introducing dry syngas cleaning processes to control halide and sulfur compounds satisfying tolerate contaminants level of gas turbine. To realize the dry process, the bench scale test facility was planned to demonstrate the first-ever halide and sulfur removal with fixed bed reactor using actual syngas from O 2 -CO 2 blown gasifier for the oxy-fuel IGCC power generation. Design parameter for the test facility was required for the candidate sorbents for halide removal and sulfur removal. Breakthrough test was performed on two kinds of halide sorbents at accelerated condition and on honeycomb desulfurization sorbent at varied space velocity condition. The results for the both sorbents for halide and sulfur exhibited sufficient removal within the satisfactory short depth of sorbent bed, as well as superior bed conversion of the impurity removal reaction. These performance evaluation of the candidate sorbents of halide and sulfur removal provided rational and affordable design parameters for the bench scale test facility to demonstrate the dry syngas cleaning process for oxy-fuel IGCC system as the scaled up step of process development. Copyright © 2017 Elsevier Ltd. All rights reserved.

A greener approach for resource recycling: Manganese bioleaching.

PubMed

Ghosh, S; Mohanty, S; Akcil, A; Sukla, L B; Das, A P

2016-07-01

In view of unremitting diminution of mineral resources, rising energy economics along with increasing global consumption of Manganese (Mn), development of environment friendly technologies for tapping alternate sources of Mn has gained importance lately. Mn recovery from mining residues using conventional approaches is extremely expensive due to high capital and energy costs involved. However lean grade ores present in millions of tons awaits the development of competent and cost effective extractive process. Mn recovery by biomining with diverse microbes is thereby recommended as a superior and green alternative to the current pyro metallurgical techniques. The synergistic effects of different factors are known to influence microbial leaching of mineral ores which includes microbiological, mineralogical, physicochemical and process parameters. Bacterial bioleaching is mostly due to enzymatic influence, however fungal bioleaching is non enzymatic. Genomic studies on microbial diversity and an insight of its metabolic pathways provides unique dimension to the mechanism of biomining microorganisms. The extraction of Mn has a massive future prospective and will play a remarkable role in altering the situation of ever-decreasing grades of ore. This review aims to encompass the different aspects of Mn bioleaching, the plethora of organisms involved, the mechanisms driving the process and the recent trends and future prospects of this green technology. Copyright © 2016 Elsevier Ltd. All rights reserved.

FPGA for Power Control of MSL Avionics

NASA Technical Reports Server (NTRS)

Wang, Duo; Burke, Gary R.

2011-01-01

A PLGT FPGA (Field Programmable Gate Array) is included in the LCC (Load Control Card), GID (Guidance Interface & Drivers), TMC (Telemetry Multiplexer Card), and PFC (Pyro Firing Card) boards of the Mars Science Laboratory (MSL) spacecraft. (PLGT stands for PFC, LCC, GID, and TMC.) It provides the interface between the backside bus and the power drivers on these boards. The LCC drives power switches to switch power loads, and also relays. The GID drives the thrusters and latch valves, as well as having the star-tracker and Sun-sensor interface. The PFC drives pyros, and the TMC receives digital and analog telemetry. The FPGA is implemented both in Xilinx (Spartan 3- 400) and in Actel (RTSX72SU, ASX72S). The Xilinx Spartan 3 part is used for the breadboard, the Actel ASX part is used for the EM (Engineer Module), and the pin-compatible, radiation-hardened RTSX part is used for final EM and flight. The MSL spacecraft uses a FC (Flight Computer) to control power loads, relays, thrusters, latch valves, Sun-sensor, and star-tracker, and to read telemetry such as temperature. Commands are sent over a 1553 bus to the MREU (Multi-Mission System Architecture Platform Remote Engineering Unit). The MREU resends over a remote serial command bus c-bus to the LCC, GID TMC, and PFC. The MREU also sends out telemetry addresses via a remote serial telemetry address bus to the LCC, GID, TMC, and PFC, and the status is returned over the remote serial telemetry data bus.

A detailed study of the 2010 fires in Russia by multiple satellite instruments: what can we learn from the UV Aerosol Indices?

NASA Astrophysics Data System (ADS)

Penning de Vries, M. J.; Wagner, T.; Fromm, M. D.

2010-12-01

For almost a month in July and August 2010, an exceptionally high number of fires occurred across western Russia. Varying fire characteristics and intensity due to differences in fuel composition and meteorological conditions caused smoke plumes to vary in color, altitude and optical density. Peat bog fires around Moscow tended to produce low-lying, whitish smoke layers, whereas some severe forest fires were found to have caused so-called pyro-Cbs: thick, mostly dark smoke plumes on top of large convective clouds that reached as high as the stratosphere. In situations where an aerosol layer overlays a cloud, many remote sensing aerosol retrievals break down due to the brightness of the “surface”. The UV Aerosol Indices (UVAI) do not suffer from this drawback, and in fact are more sensitive to absorbing aerosols if the underlying surface is bright, therefore making them very suitable for our type of investigation. However, aerosol plumes are very complex and the UVAI are only semi-quantitative measures that are determined by aerosol extinction and absorption, but also by the altitude of the aerosol plume. We therefore chose to combine our UVAI measurements from the instruments SCIAMACHY, OMI, and GOME-2 with observations by other satellite instruments, such as MODIS, MISR, MERIS, and CALIOP. We also compared the measurements to radiative transfer model calculations of many different aerosol scenarios to draw conclusions about what specific aerosol characteristics cause the variation in pyro-Cb appearances.

Subscribe to the Energy Systems Integration Newsletter | Energy Systems

Science.gov Websites

Integration Facility | NREL Subscribe to the Energy Systems Integration Newsletter Subscribe to the Energy Systems Integration Newsletter Subscribe to receive regular updates on what's happening at the Energy Systems Integration Facility and in energy systems integration research at NREL and around

Upgrades at the NASA Langley Research Center National Transonic Facility

NASA Technical Reports Server (NTRS)

Paryz, Roman W.

2012-01-01

Several projects have been completed or are nearing completion at the NASA Langley Research Center (LaRC) National Transonic Facility (NTF). The addition of a Model Flow-Control/Propulsion Simulation test capability to the NTF provides a unique, transonic, high-Reynolds number test capability that is well suited for research in propulsion airframe integration studies, circulation control high-lift concepts, powered lift, and cruise separation flow control. A 1992 vintage Facility Automation System (FAS) that performs the control functions for tunnel pressure, temperature, Mach number, model position, safety interlock and supervisory controls was replaced using current, commercially available components. This FAS upgrade also involved a design study for the replacement of the facility Mach measurement system and the development of a software-based simulation model of NTF processes and control systems. The FAS upgrades were validated by a post upgrade verification wind tunnel test. The data acquisition system (DAS) upgrade project involves the design, purchase, build, integration, installation and verification of a new DAS by replacing several early 1990's vintage computer systems with state of the art hardware/software. This paper provides an update on the progress made in these efforts. See reference 1.

A national facility for biological cryo-electron microscopy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Saibil, Helen R., E-mail: h.saibil@mail.cryst.bbk.ac.uk; Grünewald, Kay; Stuart, David I.

2015-01-01

This review provides a brief update on the use of cryo-electron microscopy for integrated structural biology, along with an overview of the plans for the UK national facility for electron microscopy being built at the Diamond synchrotron. Three-dimensional electron microscopy is an enormously powerful tool for structural biologists. It is now able to provide an understanding of the molecular machinery of cells, disease processes and the actions of pathogenic organisms from atomic detail through to the cellular context. However, cutting-edge research in this field requires very substantial resources for equipment, infrastructure and expertise. Here, a brief overview is provided ofmore » the plans for a UK national three-dimensional electron-microscopy facility for integrated structural biology to enable internationally leading research on the machinery of life. State-of-the-art equipment operated with expert support will be provided, optimized for both atomic-level single-particle analysis of purified macromolecules and complexes and for tomography of cell sections. The access to and organization of the facility will be modelled on the highly successful macromolecular crystallography (MX) synchrotron beamlines, and will be embedded at the Diamond Light Source, facilitating the development of user-friendly workflows providing near-real-time experimental feedback.« less

Development of a plan for automating integrated circuit processing

NASA Technical Reports Server (NTRS)

1971-01-01

The operations analysis and equipment evaluations pertinent to the design of an automated production facility capable of manufacturing beam-lead CMOS integrated circuits are reported. The overall plan shows approximate cost of major equipment, production rate and performance capability, flexibility, and special maintenance requirements. Direct computer control is compared with supervisory-mode operations. The plan is limited to wafer processing operations from the starting wafer to the finished beam-lead die after separation etching. The work already accomplished in implementing various automation schemes, and the type of equipment which can be found for instant automation are described. The plan is general, so that small shops or large production units can perhaps benefit. Examples of major types of automated processing machines are shown to illustrate the general concepts of automated wafer processing.

Mass tracking and material accounting in the Integral Fast Reactor (IFR)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Orechwa, Y.; Adams, C.H.; White, A.M.

1991-01-01

The Integral Fast Reactor (IFR) is a generic advanced liquid metal cooled reactor concept being developed at Argonne National Laboratory (ANL). There are a number of technical features of the IFR which contribute to its potential as a next-generation reactor. These are associated with large safety margins with regard to off-normal events involving the heat transport system, and the use of metallic fuel which makes possible the utilization of innovative fuel cycle processes. The latter feature permits fuel cycle closure the compact, low-cost reprocessing facilities, collocated with the reactor plant. These primary features are being demonstrated in the facilities atmore » ANL-West, utilizing Experimental Breeder Reactor 2 and the associated Fuel Cycle Facility (FCF) as an IFR prototype. The demonstration of this IFR prototype includes the design and implementation of the Mass-Tracking System (MTG). In this system, data from the operations of the FCF, including weights and batch-process parameters, are collected and maintained by the MTG running on distributed workstations. The components of the MTG System include: (1) an Oracle database manager with a Fortran interface, (2) a set of MTG Tasks'' which collect, manipulate and report data, (3) a set of MTG Terminal Sessions'' which provide some interactive control of the Tasks, and (4) a set of servers which manage the Tasks and which provide the communications link between the MTG System and Operator Control Stations, which control process equipment and monitoring devices within the FCF.« less

NREL, Abengoa Making Concentrating Solar Power System Manufacturing More

Science.gov Websites

Cost Effective | Energy Systems Integration Facility | NREL Abengoa NREL, Abengoa Making Concentrating Solar Power System Manufacturing More Cost Effective Abengoa is working with NREL researchers to develop a new and more cost-effective manufacturing process for critical components of concentrating solar

49 CFR 191.23 - Reporting safety-related conditions.

Code of Federal Regulations, 2010 CFR

2010-10-01

..., controls, or processes gas or LNG. (4) Any material defect or physical damage that impairs the... strength. (5) Any malfunction or operating error that causes the pressure of a pipeline or LNG facility... structural integrity of an LNG storage tank. (8) Any safety-related condition that could lead to an imminent...

Examples of Disposition Alternatives for WTP Solid Secondary Waste

DOE Office of Scientific and Technical Information (OSTI.GOV)

Seitz, R.

The Hanford Waste Treatment and Immobilization Plant is planned to produce a variety of solid secondary wastes that will require disposal at the Integrated Disposal Facility on the Hanford Site. Solid secondary wastes include a variety of waste streams that are a result of waste treatment and processing activities.

Economic and environmental evaluation of flexible integrated gasification polygeneration facilities with carbon capture and storage

EPA Science Inventory

One innovative option for reducing greenhouse gas (GHG) emissions involves pairing carbon capture and storage (CCS) with the production of synthetic fuels and electricity from co-processed coal and biomass. In this scheme, the feedstocks are first converted to syngas, from which ...

Exploring Social Equity Aspects in Integrating Technology in Primary Mathematics Education

ERIC Educational Resources Information Center

Stoilescu, Dorian

2014-01-01

This research focus on aspects of equity related to the introduction of using technology in classrooms. Technology has the potential to support mathematics pedagogy with visual representations and offer modelling and simulation facilities, increasing the creativity of the learning and teaching processes (Kaput, Ness, & Hoyles, 2008; Stoilescu…

Afghanistan: Narcotics and U.S. Policy

DTIC Science & Technology

2007-12-06

build on existing USAID programs to develop integrated systems of crop processing facilities, storage areas, roads, and markets, and to restore wheat ...Darling, “ Fungi May Be the Newest Recruits in War on Drugs Colombia,” Los Angeles Times, August 30, 2000. 105 According to a USDA official, “The

Integrating PV in Distributed Grids: Solutions and Technologies Workshop |

Science.gov Websites

Energy Systems Integration Facility | NREL Integrating PV in Distributed Grids: Solutions and Technologies Workshop Integrating PV in Distributed Grids: Solutions and Technologies Workshop In October 2015 (PV) onto the grid. The workshop was held at the Energy Systems Integration Facility. Presenters from

Energy Systems Integration News | Energy Systems Integration Facility |

Science.gov Websites

NREL News Energy Systems Integration News A monthly recap of the latest happenings at the Energy Systems Integration Facility and developments in energy systems integration (ESI) research at NREL ; said Vahan Gevorgian, chief engineer with NREL's Power Systems Engineering Center. "Results of

STS-82 Discovery payloads being integrated in VPF

NASA Image and Video Library

1997-01-30

KENNEDY SPACE CENTER, FLORIDA STS-82 PREPARATIONS VIEW --- Payload processing workers in the Kennedy Space Center (KSC) Vertical Processing Facility (VPF) prepare to integrate the Space Telescope Imaging Spectrograph (STIS), suspended at center, into the Orbiter Replacement Unit (ORU) Carrier and Scientific Instrument Protective Enclosure (SIPE). STIS will replace the Goddard High Resolution Spectrograph (GHRS) on the Hubble Space Telescope (HST). Four of the seven STS-82 crew members will perform a series of spacewalks to replace two scientific instruments with two new instruments, including STIS, and perform other tasks during the second HST servicing mission. HST was deployed nearly seven years ago and was initially serviced in 1993.

ICPS Turnover GSDO Employee Event

NASA Image and Video Library

2017-11-07

In the Space Station Processing Facility at NASA's Kennedy Space Center in Florida, a ceremony is underway marking the agency's Spacecraft/Payload Integration and Evolution (SPIE) organization formally turning over processing of the Space Launch System (SLS) rocket's Interim Cryogenic Propulsion Stage (ICPS), to the center's Ground Systems Development and Operations (GSDO) Directorate. The ICPS is seen on the left in its shipping container and is the first integrated piece of flight hardware to arrive in preparation for the uncrewed Exploration Mission-1. With the Orion attached, the ICPS sits atop the SLS rocket and will provide the spacecraft with the additional thrust needed to travel tens of thousands of miles beyond the Moon.

Characterization of extractable soil organic matter pools from African Dark Earths (AfDE): A case study in historical biochar and organic waste amendments

NASA Astrophysics Data System (ADS)

Fujiu, Manna; Plante, Alain; Ohno, Tsutomu; Solomon, Dawit; Lehmann, Johannes; Fraser, James; Leach, Melissa; Fairhead, James

2014-05-01

Anthropogenic Dark Earths are soils generated through long-term human inputs of organic and pyrogenic materials. These soils were originally discovered in the Amazon, and have since been found in Australia and in this case in Africa. African Dark Earths (AfDE) are black, highly fertile and carbon-rich soils that were formed from the original highly-weathered infertile yellowish to red Oxisols and Ultisols through an extant but hitherto overlooked climate-smart sustainable soil management system that has long been an important feature of the indigenous West African agricultural repertoire. Studies have demonstrated that ADE soils in general have significantly different organic matter properties compared to adjacent non-DE soils, largely attributable to the presence of high concentrations of ash-derived carbon. Quantification and characterization of bulk soil organic matter of several (n=11) AfDE and non-AfDE pairs of surface (0-15 cm) soils using thermal analysis techniques (TG-DSC-EGA) confirmed substantial differences in SOM composition and the presence of pyrogenic C. Such pyrogenic organic matter is generally considered recalcitrant or relatively stable, but the goal of the current study was to characterize the presumably labile, more rapidly cycling, pools of C in AfDEs through the characterization of hot water- and pyrophosphate-extractable fractions, referred to as HWEOC and PyroC respectively. Extracts were analyzed for carbon content, as well as composition using fluorescence (EEM/PARAFAC) and high resolution mass spectrometry (FTICR-MS). The amount of extractable C as a proportion of total soil C was relatively low: less than ~0.8% for HWEOC and 2.8% for PyroC. The proportion of HWEOC did not differ (P = 0.18, paired t-test) between the AfDE and the non-AfDE soils, while the proportions of PyroC were significantly larger (P = 0.001) in the AfDE soils compared to the non-AfDE soils. Preliminary analysis of the EEM/PARAFAC data suggests that AfDE samples had a greater fraction of their DOM that was more humic-like than the paired non-AfDE samples, though differences were small. Similarly, FTICR-MS analysis of hot water extracts suggests that differences among the three sites analyzed were larger than between the paired AfDE and non-AfDE extracts. Overall, in spite of substantial differences in the composition of bulk SOM, the extractable fractions appear to be relatively similar between the AfDE and non-AfDE soils.

EPA Facility Registry Service (FRS): CAMDBS

EPA Pesticide Factsheets

This web feature service contains location and facility identification information from EPA's Facility Registry Service (FRS) for the subset of facilities that link to the Clean Air Markets Division Business System (CAMDBS). Administered by the EPA Clean Air Markets Division, within the Office of Air and Radiation, CAMDBS supports the implementation of market-based air pollution control programs, including the Acid Rain Program and regional programs designed to reduce the transport of ozone. FRS identifies and geospatially locates facilities, sites or places subject to environmental regulations or of environmental interest. Using vigorous verification and data management procedures, FRS integrates facility data from EPA's national program systems, other federal agencies, and State and tribal master facility records and provides EPA with a centrally managed, single source of comprehensive and authoritative information on facilities. This data set contains the subset of FRS integrated facilities that link to CAMDBS facilities once the CAMDBS data has been integrated into the FRS database. Additional information on FRS is available at the EPA website https://www.epa.gov/enviro/facility-registry-service-frs.

Baseline tests for arc melter vitrification of INEL buried wastes. Volume 1: Facility description and summary data report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Oden, L.L.; O`Connor, W.K.; Turner, P.C.

1993-11-19

This report presents field results and raw data from the Buried Waste Integrated Demonstration (BWID) Arc Melter Vitrification Project Phase 1 baseline test series conducted by the Idaho National Engineering Laboratory (INEL) in cooperation with the U.S. Bureau of Mines (USBM). The baseline test series was conducted using the electric arc melter facility at the USBM Albany Research Center in Albany, Oregon. Five different surrogate waste feed mixtures were tested that simulated thermally-oxidized, buried, TRU-contaminated, mixed wastes and soils present at the INEL. The USBM Arc Furnace Integrated Waste Processing Test Facility includes a continuous feed system, the arc meltingmore » furnace, an offgas control system, and utilities. The melter is a sealed, 3-phase alternating current (ac) furnace approximately 2 m high and 1.3 m wide. The furnace has a capacity of 1 metric ton of steel and can process as much as 1,500 lb/h of soil-type waste materials. The surrogate feed materials included five mixtures designed to simulate incinerated TRU-contaminated buried waste materials mixed with INEL soil. Process samples, melter system operations data and offgas composition data were obtained during the baseline tests to evaluate the melter performance and meet test objectives. Samples and data gathered during this program included (a) automatically and manually logged melter systems operations data, (b) process samples of slag, metal and fume solids, and (c) offgas composition, temperature, velocity, flowrate, moisture content, particulate loading and metals content. This report consists of 2 volumes: Volume I summarizes the baseline test operations. It includes an executive summary, system and facility description, review of the surrogate waste mixtures, and a description of the baseline test activities, measurements, and sample collection. Volume II contains the raw test data and sample analyses from samples collected during the baseline tests.« less

Clinician perceptions and patient experiences of antiretroviral treatment integration in primary health care clinics, Tshwane, South Africa.

PubMed

Mathibe, Maphuthego D; Hendricks, Stephen J H; Bergh, Anne-Marie

2015-10-02

Primary Health Care (PHC) clinicians and patients are major role players in the South African antiretroviral treatment programme. Understanding their perceptions and experiences of integrated care and the management of people living with HIV and AIDS in PHC facilities is necessary for successful implementation and sustainability of integration. This study explored clinician perceptions and patient experiences of integration of antiretroviral treatment in PHC clinics. An exploratory, qualitative study was conducted in four city of Tshwane PHC facilities. Two urban and two rural facilities following different models of integration were included. A self-administered questionnaire with open-ended items was completed by 35 clinicians and four focus group interviews were conducted with HIV-positive patients. The data were coded and categories were grouped into sub-themes and themes. Workload, staff development and support for integration affected clinicians' performance and viewpoints. They perceived promotion of privacy, reduced discrimination and increased access to comprehensive care as benefits of service integration. Delays, poor patient care and patient dissatisfaction were viewed as negative aspects of integration. In three facilities patients were satisfied with integration or semi-integration and felt common queues prevented stigma and discrimination, whilst the reverse was true in the facility with separate services. Single-month issuance of antiretroviral drugs and clinic schedule organisation was viewed negatively, as well as poor staff attitudes, poor communication and long waiting times. Although a fully integrated service model is preferable, aspects that need further attention are management support from health authorities for health facilities, improved working conditions and appropriate staff development opportunities.

Coal gasification systems engineering and analysis. Appendix A: Coal gasification catalog

NASA Technical Reports Server (NTRS)

1980-01-01

The scope of work in preparing the Coal Gasification Data Catalog included the following subtasks: (1) candidate system subsystem definition, (2) raw materials analysis, (3) market analysis for by-products, (4) alternate products analysis, (5) preliminary integrated facility requirements. Definition of candidate systems/subsystems includes the identity of and alternates for each process unit, raw material requirements, and the cost and design drivers for each process design.

Continuous downstream processing for high value biological products: A Review.

PubMed

Zydney, Andrew L

2016-03-01

There is growing interest in the possibility of developing truly continuous processes for the large-scale production of high value biological products. Continuous processing has the potential to provide significant reductions in cost and facility size while improving product quality and facilitating the design of flexible multi-product manufacturing facilities. This paper reviews the current state-of-the-art in separations technology suitable for continuous downstream bioprocessing, focusing on unit operations that would be most appropriate for the production of secreted proteins like monoclonal antibodies. This includes cell separation/recycle from the perfusion bioreactor, initial product recovery (capture), product purification (polishing), and formulation. Of particular importance are the available options, and alternatives, for continuous chromatographic separations. Although there are still significant challenges in developing integrated continuous bioprocesses, recent technological advances have provided process developers with a number of attractive options for development of truly continuous bioprocessing operations. © 2015 Wiley Periodicals, Inc.

EPA Facility Registry Service (FRS): PCS_NPDES

EPA Pesticide Factsheets

This web feature service contains location and facility identification information from EPA's Facility Registry Service (FRS) for the subset of facilities that link to the Permit Compliance System (PCS) or the National Pollutant Discharge Elimination System (NPDES) module of the Integrated Compliance Information System (ICIS). PCS tracks NPDES surface water permits issued under the Clean Water Act. This system is being incrementally replaced by the NPDES module of ICIS. Under NPDES, all facilities that discharge pollutants from any point source into waters of the United States are required to obtain a permit. The permit will likely contain limits on what can be discharged, impose monitoring and reporting requirements, and include other provisions to ensure that the discharge does not adversely affect water quality. FRS identifies and geospatially locates facilities, sites or places subject to environmental regulations or of environmental interest. Using vigorous verification and data management procedures, FRS integrates facility data from EPA's national program systems, other federal agencies, and State and tribal master facility records and provides EPA with a centrally managed, single source of comprehensive and authoritative information on facilities. This data set contains the subset of FRS integrated facilities that link to NPDES facilities once the PCS or ICIS-NPDES data has been integrated into the FRS database. Additional information on FRS is available

High-speed flight propulsion systems. Progress in Astronautics and Aeronautics. Vol. 137

DOE Office of Scientific and Technical Information (OSTI.GOV)

Murthy, S.N.B.; Curran, E.T.

1991-01-01

Various papers on high-speed flight propulsion systems are presented. The topics addressed are: propulsion systems from takeoff to high-speed flight, propulsion system performance and integration for high Mach air-breathing flight, energy analysis of high-speed flight systems, waves and thermodynamics in high Mach number propulsive ducts, turbulent free shear layer mixing and combustion, turbulent mixing in supersonic combustion systems, mixing and mixing enhancement in supersonic reacting flowfields, study of combustion and heat-exchange processes in high-enthalpy short-duration facilities, and facility requirements for hypersonic propulsion system testing.

Integrated Payment and Delivery Models Offer Opportunities and Challenges for Residential Care Facilities

PubMed Central

Grabowski, David C.; Caudry, Daryl J.; Dean, Katie M.; Stevenson, David G.

2016-01-01

Under health care reform, a series of new financing and delivery models are being piloted to integrate health and long-term care services for older adults. To date, these programs have not encompassed residential care facilities, with most programs focusing on long-term care recipients in the community or the nursing home. Our analyses indicate that individuals living in residential care facilities have similarly high rates of chronic illness and Medicare utilization when compared with similar populations in the community and nursing home. These results suggest the residential care facility population could benefit greatly from models that coordinate health and long-term care. However, few providers have invested in integrated delivery models. Several challenges exist toward greater integration including the private payment of residential care facility services and the fact that residential care facilities do not share in any Medicare savings due to improved coordination of care. PMID:26438740

Postpartum family planning integration with maternal, newborn and child health services: a cross-sectional analysis of client flow patterns in India and Kenya.

PubMed

Mackenzie, Devon; Pfitzer, Anne; Maly, Christina; Waka, Charles; Singh, Gajendra; Sanyal, Abanti

2018-04-03

Maternal, newborn and child health (MNCH) services represent opportunities to integrate postpartum family planning (PPFP). Objectives were to determine levels of MNCH-family planning (FP) integration and associations between integration, client characteristics and service delivery factors in facilities that received programmatic PPFP support. Cross-sectional client flow assessment conducted during May-July 2014, over 5 days at 10 purposively selected public sector facilities in India (4 hospitals) and Kenya (2 hospitals and 4 health centres). 2158 client visits tracked (1294 India; 864 Kenya). Women aged 18 or older accessing services while pregnant and/or with a child under 2 years. PPFP/postpartum intrauterine device-Bihar, India (2012-2013); Jharkhand, India (2009-2014); Embu, Kenya (2006-2010). Maternal, infant and young child nutrition/FP integration-Bondo, Kenya (2011-2014). Proportion of visits where clients received integrated MNCH-FP services, client characteristics as predictors of MNCH-FP integration and MNCH-FP integration as predictor of length of time spent at facility. Levels of MNCH-FP integration varied widely across facilities (5.3% to 63.0%), as did proportion of clients receiving MNCH-FP integrated services by service area. Clients travelling 30-59 min were half as likely to receive integrated services versus those travelling under 30 min (OR 0.5, 95% CI 0.4 to 0.7, P<0.001). Clients receiving MNCH-FP services (vs MNCH services only) spent an average of 10.5 min longer at the facility (95% CI -0.1 to 21.9, not statistically significant). Findings suggest importance of focused programmatic support for integration by MNCH service area. FP integration was highest in areas receiving specific support. Integration does not seem to impose an undue burden on clients in terms of time spent at the facility. Clients living furthest from facilities are least likely to receive integrated services. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Combustion Integration Rack (CIR) Testing

NASA Image and Video Library

2015-02-18

Fluids and Combustion Facility (FCF), Combustion Integration Rack (CIR) during testing in the Structural Dynamics Laboratory (SDL). The Fluids and Combustion Facility (FCF) is a set of two International Space Station (ISS) research facilities designed to support physical and biological experiments in support of technology development and validation in space. The FCF consists of two modular, reconfigurable racks called the Combustion Integration Rack (CIR) and the Fluids Integration Rack (FIR). The CIR and FIR were developed at NASAʼs Glenn Research Center.

Facility Targeting, Protection and Mission Decision Making Using the VISAC Code

NASA Technical Reports Server (NTRS)

Morris, Robert H.; Sulfredge, C. David

2011-01-01

The Visual Interactive Site Analysis Code (VISAC) has been used by DTRA and several other agencies to aid in targeting facilities and to predict the associated collateral effects for the go, no go mission decision making process. VISAC integrates the three concepts of target geometric modeling, damage assessment capabilities, and an event/fault tree methodology for evaluating accident/incident consequences. It can analyze a variety of accidents/incidents at nuclear or industrial facilities, ranging from simple component sabotage to an attack with military or terrorist weapons. For nuclear facilities, VISAC predicts the facility damage, estimated downtime, amount and timing of any radionuclides released. Used in conjunction with DTRA's HPAC code, VISAC also can analyze transport and dispersion of the radionuclides, levels of contamination of the surrounding area, and the population at risk. VISAC has also been used by the NRC to aid in the development of protective measures for nuclear facilities that may be subjected to attacks by car/truck bombs.

CPICOR{trademark}: Clean power from integrated coal-ore reduction

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wintrell, R.; Miller, R.N.; Harbison, E.J.

1997-12-31

The US steel industry, in order to maintain its basic iron production, is thus moving to lower coke requirements and to the cokeless or direct production of iron. The US Department of Energy (DOE), in its Clean Coal Technology programs, has encouraged the move to new coal-based technology. The steel industry, in its search for alternative direct iron processes, has been limited to a single process, COREX{reg_sign}. The COREX{reg_sign} process, though offering commercial and environmental acceptance, produces a copious volume of offgas which must be effectively utilized to ensure an economical process. This volume, which normally exceeds the internal needsmore » of a single steel company, offers a highly acceptable fuel for power generation. The utility companies seeking to offset future natural gas cost increases are interested in this clean fuel. The COREX{reg_sign} smelting process, when integrated with a combined cycle power generation facility (CCPG) and a cryogenic air separation unit (ASU), is an outstanding example of a new generation of environmentally compatible and highly energy efficient Clean Coal Technologies. This combination of highly integrated electric power and hot metal coproduction, has been designated CPICOR{trademark}, Clean Power from Integrated Coal/Ore Reduction.« less

Energy Systems Integration Facility Insight Center | Energy Systems

Science.gov Websites

simulation data. Photo of researchers studying data on a 3-D power system profile depicting the interaction of renewable energy resources on the grid. Capabilities The Insight Center offers the following Integration Facility Insight Center Located adjacent to the Energy System Integration Facility's High

DOE Coal Gasification Multi-Test Facility: fossil fuel processing technical/professional services

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hefferan, J.K.; Lee, G.Y.; Boesch, L.P.

1979-07-13

A conceptual design, including process descriptions, heat and material balances, process flow diagrams, utility requirements, schedule, capital and operating cost estimate, and alternative design considerations, is presented for the DOE Coal Gasification Multi-Test Facility (GMTF). The GMTF, an engineering scale facility, is to provide a complete plant into which different types of gasifiers and conversion/synthesis equipment can be readily integrated for testing in an operational environment at relatively low cost. The design allows for operation of several gasifiers simultaneously at a total coal throughput of 2500 tons/day; individual gasifiers operate at up to 1200 tons/day and 600 psig using airmore » or oxygen. Ten different test gasifiers can be in place at the facility, but only three can be operated at one time. The GMTF can produce a spectrum of saleable products, including low Btu, synthesis and pipeline gases, hydrogen (for fuel cells or hydrogasification), methanol, gasoline, diesel and fuel oils, organic chemicals, and electrical power (potentially). In 1979 dollars, the base facility requires a $288 million capital investment for common-use units, $193 million for four gasification units and four synthesis units, and $305 million for six years of operation. Critical reviews of detailed vendor designs are appended for a methanol synthesis unit, three entrained flow gasifiers, a fluidized bed gasifier, and a hydrogasifier/slag-bath gasifier.« less

Integrated scheduling and resource management. [for Space Station Information System

NASA Technical Reports Server (NTRS)

Ward, M. T.

1987-01-01

This paper examines the problem of integrated scheduling during the Space Station era. Scheduling for Space Station entails coordinating the support of many distributed users who are sharing common resources and pursuing individual and sometimes conflicting objectives. This paper compares the scheduling integration problems of current missions with those anticipated for the Space Station era. It examines the facilities and the proposed operations environment for Space Station. It concludes that the pattern of interdependecies among the users and facilities, which are the source of the integration problem is well structured, allowing a dividing of the larger problem into smaller problems. It proposes an architecture to support integrated scheduling by scheduling efficiently at local facilities as a function of dependencies with other facilities of the program. A prototype is described that is being developed to demonstrate this integration concept.

Priority setting and the ethics of resource allocation within VA healthcare facilities: results of a survey.

PubMed

Foglia, Mary Beth; Pearlman, Robert A; Bottrell, Melissa M; Altemose, Jane A; Fox, Ellen

2008-01-01

Setting priorities and the subsequent allocation of resources is a major ethical issue facing healthcare facilities, including the Veterans Health Administration (VHA), the largest integrated healthcare delivery network in the United States. Yet despite the importance of priority setting and its impact on those who receive and those who provide care, we know relatively little about how clinicians and managers view allocation processes within their facilities. The purpose of this secondary analysis of survey data was to characterize staff members' perceptions regarding the fairness of healthcare ethics practices related to resource allocation in Veterans Administration (VA) facilities. The specific aim of the study was to compare the responses of clinicians, clinician managers, and non-clinician managers with respect to these survey items. We utilized a paper and web-based survey and a cross-sectional design of VHA clinicians and managers. Our sample consisted of a purposive stratified sample of 109 managers and a stratified random sample of 269 clinicians employed 20 or more hours per week in one of four VA medical centers. The four medical centers were participating as field sites selected to test the logistics of administering and reporting results of the Integrated Ethics Staff Survey, an assessment tool aimed at characterizing a broad range of ethical practices within a healthcare organization. In general, clinicians were more critical than clinician managers or non-clinician managers of the institutions' allocation processes and of the impact of resource decisions on patient care. Clinicians commonly reported that they did not (a) understand their facility's decision-making processes, (b) receive explanations from management regarding the reasons behind important allocation decisions, or (b) perceive that they were influential in allocation decisions. In addition, clinicians and managers both perceived that education related to the ethics of resource allocation was insufficient and that their facilities could increase their effectiveness in identifying and resolving ethical problems related to resource allocation. How well a healthcare facility ensures fairness in the way it allocates its resources across programs and services depends on multiple factors, including awareness by decision makers that setting priorities and allocating resources is a moral enterprise (moral awareness), the availability of a consistent process that includes important stakeholder groups (procedural justice), and concurrence by stakeholders that decisions represent outcomes that fairly balance competing interests and have a positive net effect on the quality of care (distributive justice). In this study, clinicians and managers alike identified the need for improvement in healthcare ethics practices related to resource allocation.

DOE Office of Scientific and Technical Information (OSTI.GOV)

MacDonald, Douglas G.; Clements, Samuel L.; Patrick, Scott W.

Securing high value and critical assets is one of the biggest challenges facing this nation and others around the world. In modern integrated systems, there are four potential modes of attack available to an adversary: • physical only attack, • cyber only attack, • physical-enabled cyber attack, • cyber-enabled physical attack. Blended attacks involve an adversary working in one domain to reduce system effectiveness in another domain. This enables the attacker to penetrate further into the overall layered defenses. Existing vulnerability assessment (VA) processes and software tools which predict facility vulnerabilities typically evaluate the physical and cyber domains separately. Vulnerabilitiesmore » which result from the integration of cyber-physical control systems are not well characterized and are often overlooked by existing assessment approaches. In this paper, we modified modification of the timely detection methodology, used for decades in physical security VAs, to include cyber components. The Physical and Cyber Risk Analysis Tool (PACRAT) prototype illustrates an integrated vulnerability assessment that includes cyber-physical interdependencies. Information about facility layout, network topology, and emplaced safeguards is used to evaluate how well suited a facility is to detect, delay, and respond to attacks, to identify the pathways most vulnerable to attack, and to evaluate how often safeguards are compromised for a given threat or adversary type. We have tested the PACRAT prototype on critical infrastructure facilities and the results are promising. Future work includes extending the model to prescribe the recommended security improvements via an automated cost-benefit analysis.« less

Systematic Evaluation Program (SEP) at Rocky Flats Plant: An overview of practical management issues for evaluation of natural phenomena hazards

DOE Office of Scientific and Technical Information (OSTI.GOV)

Badwan, F.M.; Herring, K.S.

1993-08-01

Many of the buildings at the Rocky Flats Plant were designed and built before modern standards were developed, including standards for protection against extreme natural phenomenon such as tornadoes, earthquakes, and floods. The purpose of the SEP is to establish an integrated approach to assessing the design adequacy of specific high and moderate hazard Rocky Flats facilities from a safety perspective and to establish a basis for defining any needed facility improvements. The SEP is to be carried out in three Phases. In Phase 1, topics to be evaluated and an evaluation plan for each topic were developed. Any differencesmore » between Current Design Requirements (CDR) or acceptance criteria and the design of existing facilities, will be identified during Phase 2 and assessed using an integrated systematic approach during Phase 3. The integrated assessment performed during Phase 3 provides a process for evaluating the differences between existing facility design and CDRs so that decisions on corrective actions can be made on the basis of relative risk reduction and cost effectiveness. These efforts will ensure that a balanced and integrated level of safety is achieved for long-term operation of these buildings. Through appropriate selection of topics and identification of the structures, systems, and components to be evaluated, the SEP will address outstanding design issues related to the prevention and mitigation of design basis accidents, including those arising from natural phenomena. The objective of the SEP is not to bring these buildings into strict compliance with current requirements, but rather to ensure that an adequate level of safety is achieved in an economical fashion.« less

Fluids and Combustion Facility: Combustion Integrated Rack Modal Model Correlation

NASA Technical Reports Server (NTRS)

McNelis, Mark E.; Suarez, Vicente J.; Sullivan, Timothy L.; Otten, Kim D.; Akers, James C.

2005-01-01

The Fluids and Combustion Facility (FCF) is a modular, multi-user, two-rack facility dedicated to combustion and fluids science in the US Laboratory Destiny on the International Space Station. FCF is a permanent facility that is capable of accommodating up to ten combustion and fluid science investigations per year. FCF research in combustion and fluid science supports NASA's Exploration of Space Initiative for on-orbit fire suppression, fire safety, and space system fluids management. The Combustion Integrated Rack (CIR) is one of two racks in the FCF. The CIR major structural elements include the International Standard Payload Rack (ISPR), Experiment Assembly (optics bench and combustion chamber), Air Thermal Control Unit (ATCU), Rack Door, and Lower Structure Assembly (Input/Output Processor and Electrical Power Control Unit). The load path through the rack structure is outlined. The CIR modal survey was conducted to validate the load path predicted by the CIR finite element model (FEM). The modal survey is done by experimentally measuring the CIR frequencies and mode shapes. The CIR model was test correlated by updating the model to represent the test mode shapes. The correlated CIR model delivery is required by NASA JSC at Launch-10.5 months. The test correlated CIR flight FEM is analytically integrated into the Shuttle for a coupled loads analysis of the launch configuration. The analysis frequency range of interest is 0-50 Hz. A coupled loads analysis is the analytical integration of the Shuttle with its cargo element, the Mini Payload Logistics Module (MPLM), in the Shuttle cargo bay. For each Shuttle launch configuration, a verification coupled loads analysis is performed to determine the loads in the cargo bay as part of the structural certification process.

ICPS Turnover GSDO Employee Event

NASA Image and Video Library

2017-11-07

Mike Bolger, Ground Systems Development and Operations Program manager at NASA's Kennedy Space Center, speaks to guests during a ceremony in the high bay of the Space Station Processing Facility. The event marked the milestone of the Space Launch System rocket's Interim Cryogenic Propulsion Stage (ICPS) being turned over from NASA's Spacecraft/Payload Integration and Evolution organization to the spaceport's Ground Systems Development and Operations directorate. The ICPS is the first integrated piece of flight hardware to arrive in preparation for the uncrewed Exploration Mission-1.

EPA Facility Registry System (FRS): NCES

EPA Pesticide Factsheets

This web feature service contains location and facility identification information from EPA's Facility Registry System (FRS) for the subset of facilities that link to the National Center for Education Statistics (NCES). The primary federal database for collecting and analyzing data related to education in the United States and other Nations, NCES is located in the U.S. Department of Education, within the Institute of Education Sciences. FRS identifies and geospatially locates facilities, sites or places subject to environmental regulations or of environmental interest. Using vigorous verification and data management procedures, FRS integrates facility data from EPA00e2??s national program systems, other federal agencies, and State and tribal master facility records and provides EPA with a centrally managed, single source of comprehensive and authoritative information on facilities. This data set contains the subset of FRS integrated facilities that link to NCES school facilities once the NCES data has been integrated into the FRS database. Additional information on FRS is available at the EPA website http://www.epa.gov/enviro/html/fii/index.html.

EPA Facility Registry Service (FRS): TRI

EPA Pesticide Factsheets

This web feature service contains location and facility identification information from EPA's Facility Registry Service (FRS) for the subset of facilities that link to the Toxic Release Inventory (TRI) System. TRI is a publicly available EPA database reported annually by certain covered industry groups, as well as federal facilities. It contains information about more than 650 toxic chemicals that are being used, manufactured, treated, transported, or released into the environment, and includes information about waste management and pollution prevention activities. FRS identifies and geospatially locates facilities, sites or places subject to environmental regulations or of environmental interest. Using vigorous verification and data management procedures, FRS integrates facility data from EPA's national program systems, other federal agencies, and State and tribal master facility records and provides EPA with a centrally managed, single source of comprehensive and authoritative information on facilities. This data set contains the subset of FRS integrated facilities that link to TRI facilities once the TRI data has been integrated into the FRS database. Additional information on FRS is available at the EPA website https://www.epa.gov/enviro/facility-registry-service-frs.

KSC-2009-2233

NASA Image and Video Library

2009-03-20

CAPE CANAVERAL, Fla. –The NASA Railroad is hauling one of the cars with an Ares I-X segment to the Rotation, Processing and Surge Facility at NASA's Kennedy Space Center in Florida. The four reusable motor segments and the nozzle exit cone, manufactured by the Ares I first-stage prime contractor Alliant Techsystems Inc., or ATK, departed Utah March 12 on the seven-day, cross-country trip to Florida. The segments will be delivered to Kennedy's Rotation, Processing and Surge Facility for final processing and integration. The booster used for the Ares I-X launch is being modified by adding new forward structures and a fifth segment simulator. The motor is the final hardware needed for the rocket's upcoming test flight this summer. The stacking operations are scheduled to begin in the Vehicle Assembly Building in April. Photo credit: NASA/Jack Pfaller

KSC-2009-2232

NASA Image and Video Library

2009-03-20

CAPE CANAVERAL, Fla. –This NASA Railroad engine is hauling one of the cars with an Ares I-X segment to the Rotation, Processing and Surge Facility at NASA's Kennedy Space Center in Florida. The four reusable motor segments and the nozzle exit cone, manufactured by the Ares I first-stage prime contractor Alliant Techsystems Inc., or ATK, departed Utah March 12 on the seven-day, cross-country trip to Florida. The segments will be delivered to Kennedy's Rotation, Processing and Surge Facility for final processing and integration. The booster used for the Ares I-X launch is being modified by adding new forward structures and a fifth segment simulator. The motor is the final hardware needed for the rocket's upcoming test flight this summer. The stacking operations are scheduled to begin in the Vehicle Assembly Building in April. Photo credit: NASA/Jack Pfaller

An employee sews thermal insulation material on the front heat shield of the Huygens probe in the PH

NASA Technical Reports Server (NTRS)

1997-01-01

An employee in the Payload Hazardous Servicing Facility (PHSF) sews thermal insulation material on the front heat shield of the Huygens probe during prelaunch processing testing and integration in that facility, with the probe's back cover in the background. The Huygens probe and the Cassini orbiter being processed at KSC are the two primary components of the Cassini spacecraft, which will be launched on a Titan IVB/Centaur expendable launch vehicle from Cape Canaveral Air Station. Cassini will explore Saturn, its rings and moons for four years. The Huygens probe, designed and developed for the European Space Agency (ESA), will be deployed from the orbiter to study the clouds, atmosphere and surface of Saturn's largest moon, Titan. The orbiter was designed and assembled at NASA's Jet Propulsion Laboratory in California. Following postflight inspections, integration of the 12 science instruments not already installed on the orbiter will be completed. Then, the parabolic high-gain antenna and the propulsion module will be mated to the orbiter, followed by the Huygens probe, which will complete spacecraft integration. The Cassini mission is targeted for an Oct. 6 launch to begin its 6.7-year journey to the Saturnian system. Arrival at the planet is expected to occur around July 1, 2004.

An employee sews thermal insulation material on the back cover and heat shield of the Huygens probe

NASA Technical Reports Server (NTRS)

1997-01-01

An employee in the Payload Hazardous Servicing Facility (PHSF) sews thermal insulation material on the back cover and heat shield of the Huygens probe during prelaunch processing, testing and integration in that facility. The Huygens probe and the Cassini orbiter being processed at KSC are the two primary components of the Cassini spacecraft, which will be launched on a Titan IVB/Centaur expendable launch vehicle from Cape Canaveral Air Station. Cassini will explore Saturn, its rings and moons for four years. The Huygens probe, designed and developed for the European Space Agency (ESA), will be deployed from the orbiter to study the clouds, atmosphere and surface of Saturn's largest moon, Titan. The orbiter was designed and assembled at NASA's Jet Propulsion Laboratory in California. Following postflight inspections, integration of the 12 science instruments not already installed on the orbiter will be completed. Then, the parabolic high-gain antenna and the propulsion module will be mated to the orbiter, followed by the Huygens probe, which will complete spacecraft integration. The Cassini mission is targeted for an Oct. 6 launch to begin its 6.7-year journey to the Saturnian system. Arrival at the planet is expected to occur around July 1, 2004.

An employee works on the top side of the experiment platform for the Huygens probe in the PHSF

NASA Technical Reports Server (NTRS)

1997-01-01

An employee in the Payload Hazardous Servicing Facility (PHSF) works on the top side of the experiment platform for the Huygens probe that will accompany the Cassini orbiter to Saturn during prelaunch processing, testing and integration in that facility. The Huygens probe and the Cassini orbiter being processed at KSC are the two primary components of the Cassini spacecraft, which will be launched on a Titan IVB/Centaur expendable launch vehicle from Cape Canaveral Air Station. Cassini will explore Saturn, its rings and moons for four years. The Huygens probe, designed and developed for the European Space Agency (ESA), will be deployed from the orbiter to study the clouds, atmosphere and surface of Saturn's largest moon, Titan. The orbiter was designed and assembled at NASA's Jet Propulsion Laboratory in California. Following postflight inspections, integration of the 12 science instruments not already installed on the orbiter will be completed. Then, the parabolic high-gain antenna and the propulsion module will be mated to the orbiter, followed by the Huygens probe, which will complete spacecraft integration. The Cassini mission is targeted for an Oct. 6 launch to begin its 6.7-year journey to the Saturnian system. Arrival at the planet is expected to occur around July 1, 2004.

KSC-97pc680

NASA Image and Video Library

1997-04-21

Workers prepare to move the shipping container with the Cassini orbiter inside the Payload Hazardous Servicing Facility (PHSF) for prelaunch processing, testing and integration. The orbiter arrived at KSC’s Shuttle Landing Facility in a U.S. Air Force C-17 air cargo plane from Edwards Air Force Base, California. The orbiter and the Huygens probe already being processed at KSC are the two primary components of the Cassini spacecraft, which will be launched on a Titan IVB/Centaur expendable launch vehicle from Cape Canaveral Air Station. Cassini will explore Saturn, its rings and moons for four years. The Huygens probe, designed and developed for the European Space Agency (ESA), will be deployed from the orbiter to study the clouds, atmosphere and surface of Saturn’s largest moon, Titan. The orbiter was designed and assembled at NASA’s Jet Propulsion Laboratory in California. Following postflight inspections, integration of the 12 science instruments not already installed on the orbiter will be completed. Then, the parabolic high-gain antenna and the propulsion module will be mated to the orbiter, followed by the Huygens probe, which will complete spacecraft integration. The Cassini mission is targeted for an Oct. 6 launch to begin its 6.7-year journey to the Saturnian system. Arrival at the planet is expected to occur around July 1, 2004

KSC-97pc682

NASA Image and Video Library

1997-04-21

Workers prepare to move the shipping container with the Cassini orbiter inside the Payload Hazardous Servicing Facility (PHSF) for prelaunch processing, testing and integration. The orbiter arrived at KSC’s Shuttle Landing Facility in a U.S. Air Force C-17 air cargo plane from Edwards Air Force Base, California. The orbiter and the Huygens probe already being processed at KSC are the two primary components of the Cassini spacecraft, which will be launched on a Titan IVB/Centaur expendable launch vehicle from Cape Canaveral Air Station. Cassini will explore Saturn, its rings and moons for four years. The Huygens probe, designed and developed for the European Space Agency (ESA), will be deployed from the orbiter to study the clouds, atmosphere and surface of Saturn’s largest moon, Titan. The orbiter was designed and assembled at NASA’s Jet Propulsion Laboratory in California. Following postflight inspections, integration of the 12 science instruments not already installed on the orbiter will be completed. Then, the parabolic high-gain antenna and the propulsion module will be mated to the orbiter, followed by the Huygens probe, which will complete spacecraft integration. The Cassini mission is targeted for an Oct. 6 launch to begin its 6.7-year journey to the Saturnian system. Arrival at the planet is expected to occur around July 1, 2004

KSC-97pc681

NASA Image and Video Library

1997-04-21

Workers prepare to move the shipping container with the Cassini orbiter inside the Payload Hazardous Servicing Facility (PHSF) for prelaunch processing, testing and integration. The orbiter arrived at KSC’s Shuttle Landing Facility in a U.S. Air Force C-17 air cargo plane from Edwards Air Force Base, California. The orbiter and the Huygens probe already being processed at KSC are the two primary components of the Cassini spacecraft, which will be launched on a Titan IVB/Centaur expendable launch vehicle from Cape Canaveral Air Station. Cassini will explore Saturn, its rings and moons for four years. The Huygens probe, designed and developed for the European Space Agency (ESA), will be deployed from the orbiter to study the clouds, atmosphere and surface of Saturn’s largest moon, Titan. The orbiter was designed and assembled at NASA’s Jet Propulsion Laboratory in California. Following postflight inspections, integration of the 12 science instruments not already installed on the orbiter will be completed. Then, the parabolic high-gain antenna and the propulsion module will be mated to the orbiter, followed by the Huygens probe, which will complete spacecraft integration. The Cassini mission is targeted for an Oct. 6 launch to begin its 6.7-year journey to the Saturnian system. Arrival at the planet is expected to occur around July 1, 2004

The SeaView EarthCube project: Lessons Learned from Integrating Across Repositories

NASA Astrophysics Data System (ADS)

Diggs, S. C.; Stocks, K. I.; Arko, R. A.; Kinkade, D.; Shepherd, A.; Olson, C. J.; Pham, A.

2017-12-01

SeaView is an NSF-funded EarthCube Integrative Activity Project working with 5 existing data repositories* to provide oceanographers with highly integrated thematic data collections in user-requested formats. The project has three complementary goals: Supporting Scientists: SeaView targets scientists' need for easy access to data of interest that are ready to import into their preferred tool. Strengthening Repositories: By integrating data from multiple repositories for science use, SeaView is helping the ocean data repositories align their data and processes and make ocean data more accessible and easily integrated. Informing EarthCube (earthcube.org): SeaView's experience as an integration demonstration can inform the larger NSF EarthCube architecture and design effort. The challenges faced in this small-scale effort are informative to geosciences cyberinfrastructure more generally. Here we focus on the lessons learned that may inform other data facilities and integrative architecture projects. (The SeaView data collections will be presented at the Ocean Sciences 2018 meeting.) One example is the importance of shared semantics, with persistent identifiers, for key integration elements across the data sets (e.g. cruise, parameter, and project/program.) These must allow for revision through time and should have an agreed authority or process for resolving conflicts: aligning identifiers and correcting errors were time consuming and often required both deep domain knowledge and "back end" knowledge of the data facilities. Another example is the need for robust provenance, and tools that support automated or semi-automated data transform pipelines that capture provenance. Multiple copies and versions of data are now flowing into repositories, and onward to long-term archives such as NOAA NCEI and umbrella portals such as DataONE. Exact copies can be identified with hashes (for those that have the skills), but it can be painfully difficult to understand the processing or format changes that differentiates versions. As more sensors are deployed, and data re-use increases, this will only become more challenging. We will discuss these, and additional lessons learned, as well as invite discussion and solutions from others doing similar work. * BCO-DMO, CCHDO, OBIS, OOI, R2R

Microvax-based data management and reduction system for the regional planetary image facilities

NASA Technical Reports Server (NTRS)

Arvidson, R.; Guinness, E.; Slavney, S.; Weiss, B.

1987-01-01

Presented is a progress report for the Regional Planetary Image Facilities (RPIF) prototype image data management and reduction system being jointly implemented by Washington University and the USGS, Flagstaff. The system will consist of a MicroVAX with a high capacity (approx 300 megabyte) disk drive, a compact disk player, an image display buffer, a videodisk player, USGS image processing software, and SYSTEM 1032 - a commercial relational database management package. The USGS, Flagstaff, will transfer their image processing software including radiometric and geometric calibration routines, to the MicroVAX environment. Washington University will have primary responsibility for developing the database management aspects of the system and for integrating the various aspects into a working system.

KSC-2009-2318

NASA Image and Video Library

2009-03-26

CAPE CANAVERAL, Fla. –In the Rotation, Processing and Surge Facility at NASA's Kennedy Space Center in Florida, the end of the Ares I-X motor segment is removed to allow propellant grain inspection of the interior. It is one of four reusable motor segments and nozzle exit cone shipped by the Ares I first-stage prime contractor Alliant Techsystems Inc. for final processing and integration in the facility. The booster used for the Ares I-X launch is being modified by adding new forward structures and a fifth segment simulator. The motor is the final hardware needed for the rocket's upcoming flight test this summer. The stacking operations are scheduled to begin in the Vehicle Assembly Building in April. Photo credit: NASA/Jim Grossmann

KSC-2009-2317

NASA Image and Video Library

2009-03-26

CAPE CANAVERAL, Fla. – In the Rotation, Processing and Surge Facility at NASA's Kennedy Space Center in Florida, technicians prepare to remove the cover from the end of the Ares I-X motor segment for propellant grain inspection of the interior. It is one of four reusable motor segments and nozzle exit cone shipped by the Ares I first-stage prime contractor Alliant Techsystems Inc. for final processing and integration in the facility. The booster used for the Ares I-X launch is being modified by adding new forward structures and a fifth segment simulator. The motor is the final hardware needed for the rocket's upcoming flight test this summer. The stacking operations are scheduled to begin in the Vehicle Assembly Building in April. Photo credit: NASA/Jim Grossmann

Implementation of Leak Test Methods for the International Space Station (ISS) Elements, Systems and Components

NASA Technical Reports Server (NTRS)

Underwood, Steve; Lvovsky, Oleg

2007-01-01

The International Space Station (ISS has Qualification and Acceptance Environmental Test Requirements document, SSP 41172 that includes many environmental tests such as Thermal vacuum & Cycling, Depress/Repress, Sinusoidal, Random, and Acoustic Vibration, Pyro Shock, Acceleration, Humidity, Pressure, Electromatic Interference (EMI)/Electromagnetic Compatibility (EMCO), etc. This document also includes (13) leak test methods for Pressure Integrity Verification of the ISS Elements, Systems, and Components. These leak test methods are well known, however, the test procedure for specific leak test method shall be written and implemented paying attention to the important procedural steps/details that, if omitted or deviated, could impact the quality of the final product and affect the crew safety. Such procedural steps/details for different methods include, but not limited to: - Sequence of testing, f or example, pressurization and submersion steps for Method I (Immersion); - Stabilization of the mass spectrometer leak detector outputs fo r Method II (vacuum Chamber or Bell jar); - Proper data processing an d taking a conservative approach while making predictions for on-orbit leakage rate for Method III(Pressure Change); - Proper Calibration o f the mass spectrometer leak detector for all the tracer gas (mostly Helium) Methods such as Method V (Detector Probe), Method VI (Hood), Method VII (Tracer Probe), Method VIII(Accumulation); - Usage of visibl ility aides for Method I (Immersion), Method IV (Chemical Indicator), Method XII (Foam/Liquid Application), and Method XIII (Hydrostatic/Visual Inspection); While some methods could be used for the total leaka ge (either internal-to-external or external-to-internal) rate requirement verification (Vacuum Chamber, Pressure Decay, Hood, Accumulation), other methods shall be used only as a pass/fail test for individual joints (e.g., welds, fittings, and plugs) or for troubleshooting purposes (Chemical Indicator, Detector Probe, Tracer Probe, Local Vacuum Chamber, Foam/Liquid Application, and Hydrostatic/Visual Inspection). Any isolation of SSP 41172 requirements have led to either retesting of hardware or accepting a risk associated with the potential system or component pressure integrity problem during flight.

Integration of research infrastructures and ecosystem models toward development of predictive ecology

NASA Astrophysics Data System (ADS)

Luo, Y.; Huang, Y.; Jiang, J.; MA, S.; Saruta, V.; Liang, G.; Hanson, P. J.; Ricciuto, D. M.; Milcu, A.; Roy, J.

2017-12-01

The past two decades have witnessed rapid development in sensor technology. Built upon the sensor development, large research infrastructure facilities, such as National Ecological Observatory Network (NEON) and FLUXNET, have been established. Through networking different kinds of sensors and other data collections at many locations all over the world, those facilities generate large volumes of ecological data every day. The big data from those facilities offer an unprecedented opportunity for advancing our understanding of ecological processes, educating teachers and students, supporting decision-making, and testing ecological theory. The big data from the major research infrastructure facilities also provides foundation for developing predictive ecology. Indeed, the capability to predict future changes in our living environment and natural resources is critical to decision making in a world where the past is no longer a clear guide to the future. We are living in a period marked by rapid climate change, profound alteration of biogeochemical cycles, unsustainable depletion of natural resources, and deterioration of air and water quality. Projecting changes in future ecosystem services to the society becomes essential not only for science but also for policy making. We will use this panel format to outline major opportunities and challenges in integrating research infrastructure and ecosystem models toward developing predictive ecology. Meanwhile, we will also show results from an interactive model-experiment System - Ecological Platform for Assimilating Data into models (EcoPAD) - that have been implemented at the Spruce and Peatland Responses Under Climatic and Environmental change (SPRUCE) experiment in Northern Minnesota and Montpellier Ecotron, France. EcoPAD is developed by integrating web technology, eco-informatics, data assimilation techniques, and ecosystem modeling. EcoPAD is designed to streamline data transfer seamlessly from research infrastructure facilities to model simulation, data assimilation, and ecological forecasting.

Rehabilitation following pediatric traumatic brain injury: variability in adherence to psychosocial quality-of-care indicators.

PubMed

Ennis, Stephanie K; Jaffe, Kenneth M; Mangione-Smith, Rita; Konodi, Mark A; MacKenzie, Ellen J; Rivara, Frederick P

2014-01-01

To examine variations in processes of pediatric inpatient rehabilitation care related to family-centered care, management of neurobehavioral and psychosocial needs, and community reintegration after traumatic brain injury. Nine acute rehabilitation facilities from geographically diverse areas of the United States. A total of 174 children with traumatic brain injury. Retrospective chart review. Adherence to care indicators (the number of times recommended care was delivered or attempted divided by the number of times care was indicated). Across facilities, adherence rates (adjusted for difficulty of delivery) ranged from 33.6% to 73.1% (95% confidence interval, 13.4-53.9, 58.7-87.4) for family-centered processes, 21.3% to 82.5% (95% confidence interval, 6.6-36.1, 67.6-97.4) for neurobehavioral and psychosocial processes, and 22.7% to 80.3% (95% confidence interval, 5.3-40.1, 68.1-92.5) for community integration processes. Within facilities, standard deviations for adherence rates were large (24.3-34.9, family-centered domain; 22.6-34.2, neurobehavioral and psychosocial domain; and 21.6-40.5, community reintegration domain). The current state of acute rehabilitation care for children with traumatic brain injury is variable across different quality-of-care indicators addressing neurobehavioral and psychosocial needs and facilitating community reintegration of the patient and the family. Individual rehabilitation facilities demonstrate inconsistent adherence to different indicators and inconsistent performance across different care domains.

Goals and strategies in the global control design of the OAJ Robotic Observatory

NASA Astrophysics Data System (ADS)

Yanes-Díaz, A.; Rueda-Teruel, S.; Antón, J. L.; Rueda-Teruel, F.; Moles, M.; Cenarro, A. J.; Marín-Franch, A.; Ederoclite, A.; Gruel, N.; Varela, J.; Cristóbal-Hornillos, D.; Chueca, S.; Díaz-Martín, M. C.; Guillén, L.; Luis-Simoes, R.; Maícas, N.; Lamadrid, J. L.; López-Sainz, A.; Hernández-Fuertes, J.; Valdivielso, L.; Mendes de Oliveira, C.; Penteado, P.; Schoenell, W.; Kanaan, A.

2012-09-01

There are many ways to solve the challenging problem of making a high performance robotic observatory from scratch. The Observatorio Astrofísico de Javalambre (OAJ) is a new astronomical facility located in the Sierra de Javalambre (Teruel, Spain) whose primary role will be to conduct all-sky astronomical surveys. The OAJ control system has been designed from a global point of view including astronomical subsystems as well as infrastructures and other facilities. Three main factors have been considered in the design of a global control system for the robotic OAJ: quality, reliability and efficiency. We propose CIA (Control Integrated Architecture) design and OEE (Overall Equipment Effectiveness) as a key performance indicator in order to improve operation processes, minimizing resources and obtaining high cost reduction whilst maintaining quality requirements. The OAJ subsystems considered for the control integrated architecture are the following: two wide-field telescopes and their instrumentation, active optics subsystems, facilities for sky quality monitoring (seeing, extinction, sky background, sky brightness, cloud distribution, meteorological station), domes and several infrastructure facilities such as water supply, glycol water, water treatment plant, air conditioning, compressed air, LN2 plant, illumination, surveillance, access control, fire suppression, electrical generators, electrical distribution, electrical consumption, communication network, Uninterruptible Power Supply and two main control rooms, one at the OAJ and the other remotely located in Teruel, 40km from the observatory, connected through a microwave radio-link. This paper presents the OAJ strategy in control design to achieve maximum quality efficiency for the observatory processes and operations, giving practical examples of our approach.

Veggie Harvest

NASA Image and Video Library

2017-10-27

Nicole Dufour, flight integration lead, communicates directly with astronaut Joe Acaba during installation of NASA’s Advanced Plant Habitat in the Japanese Kibo module on the International Space Station. Dufour is in the Experiment Monitoring Room in the Space Station Processing Facility at Kennedy Space Center in Florida. The procedures to install the system took about six hours.

MPLM Donatello is offloaded at the SLF

NASA Technical Reports Server (NTRS)

2001-01-01

At the KSC Shuttle Landing Facility, the Italian Space Agency's Multi- Purpose Logistics Module Donatello begins rolling out of the Airbus '''Beluga''' air cargo plane that brought it from the factory of Alenia Aerospazio in Turin, Italy. The third of three for the International Space Station, the module will be transported to the Space Station Processing Facility for processing. Among the activities for the payload test team are integrated electrical tests with other Station elements in the SSPF, leak tests, electrical and software compatibility tests with the Space Shuttle (using the Cargo Integrated Test equipment) and an Interface Verification Test once the module is installed in the Space Shuttle's payload bay at the launch pad. The most significant mechanical task to be performed on Donatello in the SSPF is the installation and outfitting of the racks for carrying the various experiments and cargo.

MPLM Donatello is offloaded at the SLF

NASA Technical Reports Server (NTRS)

2001-01-01

At the KSC Shuttle Landing Facility, an Airbus '''Beluga''' air cargo plane opens to reveal its cargo, the Italian Space Agency's Multi- Purpose Logistics Module Donatello, from the factory of Alenia Aerospazio in Turin, Italy. The third of three for the International Space Station, the module will be transported to the Space Station Processing Facility for processing. Among the activities for the payload test team are integrated electrical tests with other Station elements in the SSPF, leak tests, electrical and software compatibility tests with the Space Shuttle (using the Cargo Integrated Test equipment) and an Interface Verification Test once the module is installed in the Space Shuttle's payload bay at the launch pad. The most significant mechanical task to be performed on Donatello in the SSPF is the installation and outfitting of the racks for carrying the various experiments and cargo.

MPLM Donatello is offloaded at the SLF

NASA Technical Reports Server (NTRS)

2001-01-01

At the KSC Shuttle Landing Facility, the Italian Space Agency's Multi- Purpose Logistics Module Donatello rolls out of the Airbus '''Beluga''' air cargo plane that brought it from the factory of Alenia Aerospazio in Turin, Italy. The third of three for the International Space Station, the module will be transported to the Space Station Processing Facility for processing. Among the activities for the payload test team are integrated electrical tests with other Station elements in the SSPF, leak tests, electrical and software compatibility tests with the Space Shuttle (using the Cargo Integrated Test equipment) and an Interface Verification Test once the module is installed in the Space Shuttle's payload bay at the launch pad. The most significant mechanical task to be performed on Donatello in the SSPF is the installation and outfitting of the racks for carrying the various experiments and cargo.

Integrated Energy System with Beneficial Carbon Dioxide (CO2) Use - Final Scientific/Technical Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sun, Xiaolei; Rink, Nancy T

2011-04-29

This report presents an integrated energy system that combines the production of substitute natural gas through coal hydrogasification with an algae process for beneficial carbon dioxide (CO2) use and biofuel production (funded under Department of Energy (DOE) contract DE-FE0001099). The project planned to develop, test, operate and evaluate a 2 ton-per-day coal hydrogasification plant and 25-acre algae farm at the Arizona Public Service (APS) 1000 Megawatt (MW) Cholla coal-fired power plant in Joseph City, Arizona. Conceptual design of the integrated system was undertaken with APS partners Air Liquide (AL) and Parsons. The process engineering was separated into five major areas:more » flue gas preparation and CO2 delivery, algae farming, water management, hydrogasification, and biofuel production. The process flow diagrams, energy and material balances, and preliminary major equipment needs for each major area were prepared to reflect integrated process considerations and site infrastructure design basis. The total project also included research and development on a bench-scale hydrogasifier, one-dimensional (1-D) kinetic-model simulation, extensive algae stressing, oil extraction, lipid analysis and a half-acre algae farm demonstration at APS?s Redhawk testing facility. During the project, a two-acre algae testing facility with a half-acre algae cultivation area was built at the APS Redhawk 1000 MW natural gas combined cycle power plant located 55 miles west of Phoenix. The test site integrated flue gas delivery, CO2 capture and distribution, algae cultivation, algae nursery, algae harvesting, dewatering and onsite storage as well as water treatment. The site environmental, engineering, and biological parameters for the cultivators were monitored remotely. Direct biodiesel production from biomass through an acid-catalyzed transesterification reaction and a supercritical methanol transesterification reaction were evaluated. The highest oil-to-biodiesel conversion of 79.9% was achieved with a stressed algae sample containing 40% algae oil. The effort concluded that producing biodiesel directly from the algae biomass could be an efficient, cost-effective and readily scalable way to produce biodiesel by eliminating the oil extraction process.« less

EPA Facility Registry Service (FRS): RCRA

EPA Pesticide Factsheets

This web feature service contains location and facility identification information from EPA's Facility Registry Service (FRS) for the subset of hazardous waste facilities that link to the Resource Conservation and Recovery Act Information System (RCRAInfo). EPA's comprehensive information system in support of the Resource Conservation and Recovery Act (RCRA) of 1976 and the Hazardous and Solid Waste Amendments (HSWA) of 1984, RCRAInfo tracks many types of information about generators, transporters, treaters, storers, and disposers of hazardous waste. FRS identifies and geospatially locates facilities, sites or places subject to environmental regulations or of environmental interest. Using vigorous verification and data management procedures, FRS integrates facility data from EPA's national program systems, other federal agencies, and State and tribal master facility records and provides EPA with a centrally managed, single source of comprehensive and authoritative information on facilities. This data set contains the subset of FRS integrated facilities that link to RCRAInfo hazardous waste facilities once the RCRAInfo data has been integrated into the FRS database. Additional information on FRS is available at the EPA website https://www.epa.gov/enviro/facility-registry-service-frs

Hydrodynamic Test Facilities at ARL/PSU.

DTIC Science & Technology

1982-02-12

integral scale of 1.25 cm, by the addition of honey- comb in the settling section; and (4) the development of electro- optical measuring techniques. In...the NASA tunnel and its very high velocity, has been to study the process of cavitation damage [13]. Recent studies at ARL/PSU have confirmed the...at frequencies > 300 Hz. When used in con- junction with other sensors located in the test section, dual- channel signal processing can be used to

Fuel quality/processing study. Volume 3: Fuel upgrading studies

NASA Technical Reports Server (NTRS)

Jones, G. E., Jr.; Bruggink, P.; Sinnett, C.

1981-01-01

The methods used to calculate the refinery selling prices for the turbine fuels of low quality are described. Detailed descriptions and economics of the upgrading schemes are included. These descriptions include flow diagrams showing the interconnection between processes and the stream flows involved. Each scheme is in a complete, integrated, stand alone facility. Except for the purchase of electricity and water, each scheme provides its own fuel and manufactures, when appropriate, its own hydrogen.

Fuel Distribution Systems | Energy Systems Integration Facility | NREL

Science.gov Websites

Fuel Distribution Systems Fuel Distribution Systems The Energy Systems Integration Facility's integrated fuel distribution systems provide natural gas, hydrogen, and diesel throughout its laboratories in two laboratories: the Power Systems Integration Laboratory and the Energy Storage Laboratory. Each

Challenges in integrating multidisciplinary data into a single e-infrastructure

NASA Astrophysics Data System (ADS)

Atakan, Kuvvet; Jeffery, Keith G.; Bailo, Daniele; Harrison, Matthew

2015-04-01

The European Plate Observing System (EPOS) aims to create a pan-European infrastructure for solid Earth science to support a safe and sustainable society. The mission of EPOS is to monitor and understand the dynamic and complex Earth system by relying on new e-science opportunities and integrating diverse and advanced Research Infrastructures in Europe for solid Earth Science. EPOS will enable innovative multidisciplinary research for a better understanding of the Earth's physical and chemical processes that control earthquakes, volcanic eruptions, ground instability and tsunami as well as the processes driving tectonics and Earth's surface dynamics. EPOS will improve our ability to better manage the use of the subsurface of the Earth. Through integration of data, models and facilities EPOS will allow the Earth Science community to make a step change in developing new concepts and tools for key answers to scientific and socio-economic questions concerning geo-hazards and geo-resources as well as Earth sciences applications to the environment and to human welfare. EPOS is now getting into its Implementation Phase (EPOS-IP). One of the main challenges during the implementation phase is the integration of multidisciplinary data into a single e-infrastructure. Multidisciplinary data are organized and governed by the Thematic Core Services (TCS) and are driven by various scientific communities encompassing a wide spectrum of Earth science disciplines. TCS data, data products and services will be integrated into a platform "the ICS system" that will ensure their interoperability and access to these services by the scientific community as well as other users within the society. This requires dedicated tasks for interactions with the various TCS-WPs, as well as the various distributed ICS (ICS-Ds), such as High Performance Computing (HPC) facilities, large scale data storage facilities, complex processing and visualization tools etc. Computational Earth Science (CES) services are identified as a transversal activity and as such need to be harmonized and provided within the ICS. In order to develop a metadata catalogue and the ICS system, the content from the entire spectrum of services included in TCS, ICS-Ds as well as CES activities, need to be organized in a systematic manner taking into account global and European IT-standards, while complying with the user needs and data provider requirements.

Systems Engineering and Integration for Advanced Life Support System and HST

NASA Technical Reports Server (NTRS)

Kamarani, Ali K.

2005-01-01

Systems engineering (SE) discipline has revolutionized the way engineers and managers think about solving issues related to design of complex systems: With continued development of state-of-the-art technologies, systems are becoming more complex and therefore, a systematic approach is essential to control and manage their integrated design and development. This complexity is driven from integration issues. In this case, subsystems must interact with one another in order to achieve integration objectives, and also achieve the overall system's required performance. Systems engineering process addresses these issues at multiple levels. It is a technology and management process dedicated to controlling all aspects of system life cycle to assure integration at all levels. The Advanced Integration Matrix (AIM) project serves as the systems engineering and integration function for the Human Support Technology (HST) program. AIM provides means for integrated test facilities and personnel for performance trade studies, analyses, integrated models, test results, and validated requirements of the integration of HST. The goal of AIM is to address systems-level integration issues for exploration missions. It will use an incremental systems integration approach to yield technologies, baselines for further development, and possible breakthrough concepts in the areas of technological and organizational interfaces, total information flow, system wide controls, technical synergism, mission operations protocols and procedures, and human-machine interfaces.

Development of the advanced life support Systems Integration Research Facility at NASA's Johnson Space Center

NASA Technical Reports Server (NTRS)

Tri, Terry O.; Thompson, Clifford D.

1992-01-01

Future NASA manned missions to the moon and Mars will require development of robust regenerative life support system technologies which offer high reliability and minimal resupply. To support the development of such systems, early ground-based test facilities will be required to demonstrate integrated, long-duration performance of candidate regenerative air revitalization, water recovery, and thermal management systems. The advanced life support Systems Integration Research Facility (SIRF) is one such test facility currently being developed at NASA's Johnson Space Center. The SIRF, when completed, will accommodate unmanned and subsequently manned integrated testing of advanced regenerative life support technologies at ambient and reduced atmospheric pressures. This paper provides an overview of the SIRF project, a top-level description of test facilities to support the project, conceptual illustrations of integrated test article configurations for each of the three SIRF systems, and a phased project schedule denoting projected activities and milestones through the next several years.

An Architecture for Intelligent Systems Based on Smart Sensors

NASA Technical Reports Server (NTRS)

Schmalzel, John; Figueroa, Fernando; Morris, Jon; Mandayam, Shreekanth; Polikar, Robi

2004-01-01

Based on requirements for a next-generation rocket test facility, elements of a prototype Intelligent Rocket Test Facility (IRTF) have been implemented. A key component is distributed smart sensor elements integrated using a knowledgeware environment. One of the specific goals is to imbue sensors with the intelligence needed to perform self diagnosis of health and to participate in a hierarchy of health determination at sensor, process, and system levels. The preliminary results provide the basis for future advanced development and validation using rocket test stand facilities at Stennis Space Center (SSC). We have identified issues important to further development of health-enabled networks, which should be of interest to others working with smart sensors and intelligent health management systems.

The NASA integrated test facility and its impact on flight research

NASA Technical Reports Server (NTRS)

Mackall, D. A.; Pickett, M. D.; Schilling, L. J.; Wagner, C. A.

1988-01-01

The Integrated Test Facility (ITF), being built at NASA Ames-Dryden Flight Research Facility, will provide new test capabilities for emerging research aircraft. An overview of the ITF and the challenges being addressed by this unique facility are outlined. The current ITF capabilities, being developed with the X-29 Forward Swept Wing Program, are discussed along with future ITF activities.

Auditing chronic disease care: Does it make a difference?

PubMed

Essel, Vivien; van Vuuren, Unita; De Sa, Angela; Govender, Srini; Murie, Katie; Schlemmer, Arina; Gunst, Colette; Namane, Mosedi; Boulle, Andrew; de Vries, Elma

2015-06-26

An integrated audit tool was developed for five chronic diseases, namely diabetes, hypertension, asthma, chronic obstructive pulmonary disease and epilepsy. Annual audits have been done in the Western Cape Metro district since 2009. The year 2012 was the first year that all six districts in South Africa's Western Cape Province participated in the audit process. To determine whether clinical audits improve chronic disease care in health districts over time. Western Cape Province, South Africa. Internal audits were conducted of primary healthcare facility processes and equipment availability as well as a folder review of 10 folders per chronic condition per facility. Random systematic sampling was used to select the 10 folders for the folder review. Combined data for all facilities gave a provincial overview and allowed for comparison between districts. Analysis was done comparing districts that have been participating in the audit process from 2009 to 2010 ('2012 old') to districts that started auditing recently ('2012 new'). The number of facilities audited has steadily increased from 29 in 2009 to 129 in 2012. Improvements between different years have been modest, and the overall provincial average seemed worse in 2012 compared to 2011. However, there was an improvement in the '2012 old' districts compared to the '2012 new' districts for both the facility audit and the folder review, including for eight clinical indicators, with '2012 new' districts being less likely to record clinical processes (OR 0.25, 95% CI 0.21-0.31). These findings are an indication of the value of audits to improve care processes over the long term. It is hoped that this improvement will lead to improved patient outcomes.

Auditing chronic disease care: Does it make a difference?

PubMed Central

van Vuuren, Unita; De Sa, Angela; Govender, Srini; Murie, Katie; Schlemmer, Arina; Gunst, Colette; Namane, Mosedi; Boulle, Andrew; de Vries, Elma

2015-01-01

Background An integrated audit tool was developed for five chronic diseases, namely diabetes, hypertension, asthma, chronic obstructive pulmonary disease and epilepsy. Annual audits have been done in the Western Cape Metro district since 2009. The year 2012 was the first year that all six districts in South Africa's Western Cape Province participated in the audit process. Aim To determine whether clinical audits improve chronic disease care in health districts over time. Setting Western Cape Province, South Africa. Methods Internal audits were conducted of primary healthcare facility processes and equipment availability as well as a folder review of 10 folders per chronic condition per facility. Random systematic sampling was used to select the 10 folders for the folder review. Combined data for all facilities gave a provincial overview and allowed for comparison between districts. Analysis was done comparing districts that have been participating in the audit process from 2009 to 2010 (‘2012 old’) to districts that started auditing recently (‘2012 new’). Results The number of facilities audited has steadily increased from 29 in 2009 to 129 in 2012. Improvements between different years have been modest, and the overall provincial average seemed worse in 2012 compared to 2011. However, there was an improvement in the ‘2012 old’ districts compared to the ‘2012 new’ districts for both the facility audit and the folder review, including for eight clinical indicators, with ‘2012 new’ districts being less likely to record clinical processes (OR 0.25, 95% CI 0.21–0.31). Conclusion These findings are an indication of the value of audits to improve care processes over the long term. It is hoped that this improvement will lead to improved patient outcomes. PMID:26245615

Mission Success for Combustion Science

NASA Technical Reports Server (NTRS)

Weiland, Karen J.

2004-01-01

This presentation describes how mission success for combustion experiments has been obtained in previous spaceflight experiments and how it will be obtained for future International Space Station (ISS) experiments. The fluids and combustion facility is a payload planned for the ISS. It is composed of two racks: the fluids Integrated rack and the Combustion INtegrated Rack (CIR). Requirements for the CIR were obtained from a set of combustion basis experiments that served as surrogates for later experiments. The process for experiments that fly on the ISS includes proposal selection, requirements and success criteria definition, science and engineering reviews, mission operations, and postflight operations. By following this process, the microgravity combustion science program has attained success in 41 out of 42 experiments.

Integrated manufacturing approach to attain benchmark team performance

NASA Astrophysics Data System (ADS)

Chen, Shau-Ron; Nguyen, Andrew; Naguib, Hussein

1994-09-01

A Self-Directed Work Team (SDWT) was developed to transfer a polyimide process module from the research laboratory to our wafer fab facility for applications in IC specialty devices. The SDWT implemented processes and tools based on the integration of five manufacturing strategies for continuous improvement. These were: Leadership Through Quality (LTQ), Total Productive Maintenance (TMP), Cycle Time Management (CTM), Activity-Based Costing (ABC), and Total Employee Involvement (TEI). Utilizing these management techniques simultaneously, the team achieved six sigma control of all critical parameters, increased Overall Equipment Effectiveness (OEE) from 20% to 90%, reduced cycle time by 95%, cut polyimide manufacturing cost by 70%, and improved its overall team member skill level by 33%.

An integrated exhaust gas analysis system with self-contained data processing and automatic calibration

NASA Technical Reports Server (NTRS)

Anderson, R. C.; Summers, R. L.

1981-01-01

An integrated gas analysis system designed to operate in automatic, semiautomatic, and manual modes from a remote control panel is described. The system measures the carbon monoxide, oxygen, water vapor, total hydrocarbons, carbon dioxide, and oxides of nitrogen. A pull through design provides increased reliability and eliminates the need for manual flow rate adjustment and pressure correction. The system contains two microprocessors to range the analyzers, calibrate the system, process the raw data to units of concentration, and provides information to the facility research computer and to the operator through terminal and the control panels. After initial setup, the system operates for several hours without significant operator attention.

Automated inspection of turbine blades: Challenges and opportunities

NASA Technical Reports Server (NTRS)

Mehta, Manish; Marron, Joseph C.; Sampson, Robert E.; Peace, George M.

1994-01-01

Current inspection methods for complex shapes and contours exemplified by aircraft engine turbine blades are expensive, time-consuming and labor intensive. The logistics support of new manufacturing paradigms such as integrated product-process development (IPPD) for current and future engine technology development necessitates high speed, automated inspection of forged and cast jet engine blades, combined with a capability of retaining and retrieving metrology data for process improvements upstream (designer-level) and downstream (end-user facilities) at commercial and military installations. The paper presents the opportunities emerging from a feasibility study conducted using 3-D holographic laser radar in blade inspection. Requisite developments in computing technologies for systems integration of blade inspection in production are also discussed.

Conducting Research on the International Space Station Using the EXPRESS Rack Facilities

NASA Technical Reports Server (NTRS)

Thompson, Sean W.; Lake, Robert E.

2014-01-01

EXPRESS Racks provide capability for payload access to ISS resources. The successful on-orbit operations and versatility of the EXPRESS Rack has facilitated the operations of many scientific areas, with the promise of continued payload support for years to come. EXPRESS Racks are currently deployed in the US Lab, Columbus and JEM. Process improvements and enhancements continue to improve the accommodations and make the integration and operations process more efficient. Payload Integration Managers serve as the primary interface between the ISS Program and EXPRESS Payload Developers. EXPRESS Project coordinates across multiple functional areas and organizations to ensure integrated EXPRESS Rack and subrack products and hardware are complete, accurate, on time, safe, and certified for flight. NASA is planning to expand the EXPRESS payload capacity by developing new Basic Express Racks expected to be on ISS in 2018.

Energy Systems Integration News | Energy Systems Integration Facility |

Science.gov Websites

-matter experts to develop cyber-physical systems security testing methodologies and resilience best the Energy Systems Integration Facility as part of NREL's work with SolarCity and the Hawaiian Electric Companies. Photo by Amy Glickson, NREL Welcome to Energy Systems Integration News, NREL's monthly

Antidepressant-like effect of food-derived pyroglutamyl peptides in mice.

PubMed

Yamamoto, Yukako; Mizushige, Takafumi; Mori, Yukiha; Shimmura, Yuki; Fukutomi, Ruuta; Kanamoto, Ryuhei; Ohinata, Kousaku

2015-06-01

The N-terminal glutamine residue, exposed by enzymatic cleavage of precursor proteins, is known to be modified to a pyroglutamyl residue with a cyclic structure in not only endogenous but also food-derived peptides. We investigated the effects of wheat-derived pyroglutamyl peptides on emotional behaviors. Pyroglutamyl leucine (pyroGlu-Leu, pEL) and pyroglutamyl glutaminyl leucine (pyroGlu-Gln-Leu, pEQL) exhibited antidepressant-like activity in the tail suspension and forced swim tests in mice. pEQL exhibited more potent antidepressant-like activity than pEL after i.p. and i.c.v. administration. pEQL exhibited antidepressant-like activity at a lower dose than Gln-Gln-Leu, suggesting that pyroglutamyl peptide had more potent activity. To examine whether pyroglutamyl peptides increased hippocampus neurogenesis, associated with the effects of antidepressants, we measured 5-bromo-2'-deoxyuridine (BrdU) incorporation. pEL and pEQL increased BrdU-positive cells in the dentate gyrus of the hippocampus. Intriguingly, pEL did not increase hippocampal mRNA and protein expression of brain-derived neurotrophic factor (BDNF), which is a factor associated with both neuropoietic and antidepressive effects. Thus, pyroglutamyl peptides may enhance hippocampal neurogenesis via a pathway independent of BDNF. We also confirmed that pEL and pEQL were produced in the subtilisin digest of major wheat proteins, glutenin and gliadin, after heat treatment. pEL and pEQL are the first peptides derived from wheat proteins to be shown to exhibit an antidepressant-like activity. Copyright © 2015 Elsevier Ltd. All rights reserved.

Properties of the LiCl-KCl-Li2O system as operating medium for pyro-chemical reprocessing of spent nuclear fuel

NASA Astrophysics Data System (ADS)

Mullabaev, Albert; Tkacheva, Olga; Shishkin, Vladimir; Kovrov, Vadim; Zaikov, Yuriy; Sukhanov, Leonid; Mochalov, Yuriy

2018-03-01

Crystallization temperatures (liquidus and solidus) in the LiCl-Li2O and (LiCl-KCl)-Li2O systems with the KCl content of 10 and 20 mol.% were obtained with independent methods of thermal analysis using cooling curves, isothermal saturation, and differential scanning calorimetry. The linear sweep voltammetry was applied to control the time of the equilibrium establishment in the molten system after the Li2O addition, which depended on the composition of the base melt and the concentration of Li2O. The fragments of the binary LiCl-Li2O and quazi-binary [LiCl-KCl(10 mol.%)]-Li2O and [LiCl-KCl(20 mol.%)]-Li2O phase diagrams in the Li2O concentration range from 0 to 12 mol.% were obtained. The KCl presence in the LiCl-KCl-Li2O molten mixture in the amount of 10 and 20 mol.% reduces the liquidus temperature by 30 and 80°, respectively, but the region of the homogeneous molten state of the system is considerably narrowed, which complicates its practical application. The Li2O solubility in the molten LiCl, LiCl-KCl(10 mol.%) and LiCl-KCl(20 mol.%) decreases with increasing the KCl content and is equal to 11.5, 7.7 and 3.9 mol.% at 650°С, respectively. The LiCl-KCl melt with 10 mol.% KCl can be recommended for practical use as a medium for the SNF pyro-chemical reprocessing at temperature below 700 °C.

Molecular and chiral analyses of some protein amino acid derivatives in the Murchison and Murray meteorite

NASA Astrophysics Data System (ADS)

Pizzarello, Sandra; Cooper, George W.

2001-07-01

The varied organic suite extracted from the Murchison meteorite contains several amino acids that are common to the biosphere. Some of these have been found to be non-racemic, but the indigenous nature of their L-enantiomeric excesses has been subject to debate in view of possible terrestrial contamination. We have investigated two amino acids of common terrestrial and meteoritic occurrence, alanine and glutamic acid, and assessed their indigenous enantiomeric ratios in the Murchison and Murray meteorites through the ratios of some of their derivatives. Analyzed were: N-acetyl alanine, ??imino propioacetic acid, N-acetyl glutamic acid and pyroglutamic acid. Both alanine derivatives were found to be racemic, while those of glutamic acid showed L-enantiomeric excesses varying from 16% to 47.2% for pyroglutamic acid, and from 8.6% to 41% for N-acetyl glutamic acid. The ?13C was determined for the two enantiomers of Murchison pyroglutamic acid both before and after acid hydrolysis of the lactam to glutamic acid. The values of +27.7 (D-pyro), +10.0 (L-pyro), +32.2 (D-glu) and +14.6 (L-glu) were obtained. The racemic nature of alanine derivatives strongly suggests that alanine itself, as indigenous to the meteorite, is racemic. The explanation of the L-enantiomeric excesses found for glutamic acid derivatives is less direct; however, the variability of the enantiomeric ratios for these compounds and the distinctly lower ?13C values determined for pyroglutamic L-enantiomer point to a terrestrial contamination, possibly dating to the time of fall.

On the damping effect due to bolted junctions in space structures subjected to pyro-shock

NASA Astrophysics Data System (ADS)

de Benedetti, M.; Garofalo, G.; Zumpano, M.; Barboni, R.

2007-06-01

The damping due to bolted or riveted joints in the dynamics of assembled structures subjected to pyro-shock has been studied. A relevant effect in this phenomenon is the micro-slip between the jointed surfaces. In order to verify the feasibility and the reliability of the numerical analyses performed on structures with junctions, the numerical results obtained by the finite elements method have been compared with those obtained experimentally. Several numerical analyses, in which friction forces have been represented as nonlinear loads, have been carried out for the FE models of two application cases: an electronic unit mounted within the Radarsat-2 satellite, and the complete Cosmo-Skymed spacecraft. Considering the load type, involving a typical high frequency response spectrum between 100 and 10 000 Hz, both numerical and experimental data have been reduced to the shock response spectrum form. After the comparative evaluation, taking into account also the damping effect, the agreement between numerical results and experimental data has been evaluated. The proposed numerical approach yields an effective and less expensive instrument, able to provide indications in the design phase, to allow the prevision of the dynamic behaviour of the structure for the prevention of failures in units or systems mounted within the spacecraft or launch vehicle. With the proposed model, it is possible to determine in a simple and direct way the characteristics of the damping due to the single bolted and riveted joints, and use them in similar multiple joints in the complete structure assembling or substructuring.

Kistler reusable vehicle facility design and operational approach

NASA Astrophysics Data System (ADS)

Fagan, D.; McInerney, F.; Johnston, C.; Tolson, B.

Kistler Aerospace Corporation is designing and developing the K-1, the world's first fully reusable aerospace vehicle to deliver satellites into orbit. The K-1 vehicle test program will be conducted in Woomera, Australia, with commercial operations scheduled to begin shortly afterwards. Both stages of the K-1 will return to the launch site utilizing parachutes and airbags for a soft landing within 24 h after launch. The turnaround flow of the two stages will cycle from landing site to a maintenance/refurbishment facility and through the next launch in only 9 days. Payload processing will occur in a separate facility in parallel with recovery and refurbishment operations. The vehicle design and on-board checkout capability of the avionics system eliminates the need for an abundance of ground checkout equipment. Payload integration, vehicle assembly, and K-1 transport to the launch pad will be performed horizontally, simplifying processing and reducing infrastructure requirements. This simple, innovative, and cost-effective approach will allow Kistler to offer its customers flexible, low-cost, and on-demand launch services.

Fine grained event processing on HPCs with the ATLAS Yoda system

NASA Astrophysics Data System (ADS)

Calafiura, Paolo; De, Kaushik; Guan, Wen; Maeno, Tadashi; Nilsson, Paul; Oleynik, Danila; Panitkin, Sergey; Tsulaia, Vakhtang; Van Gemmeren, Peter; Wenaus, Torre

2015-12-01

High performance computing facilities present unique challenges and opportunities for HEP event processing. The massive scale of many HPC systems means that fractionally small utilization can yield large returns in processing throughput. Parallel applications which can dynamically and efficiently fill any scheduling opportunities the resource presents benefit both the facility (maximal utilization) and the (compute-limited) science. The ATLAS Yoda system provides this capability to HEP-like event processing applications by implementing event-level processing in an MPI-based master-client model that integrates seamlessly with the more broadly scoped ATLAS Event Service. Fine grained, event level work assignments are intelligently dispatched to parallel workers to sustain full utilization on all cores, with outputs streamed off to destination object stores in near real time with similarly fine granularity, such that processing can proceed until termination with full utilization. The system offers the efficiency and scheduling flexibility of preemption without requiring the application actually support or employ check-pointing. We will present the new Yoda system, its motivations, architecture, implementation, and applications in ATLAS data processing at several US HPC centers.

Stretchable V2O5/PEDOT supercapacitors: a modular fabrication process and charging with triboelectric nanogenerators.

PubMed

Qi, Ruijie; Nie, Jinhui; Liu, Mingyang; Xia, Mengyang; Lu, Xianmao

2018-04-26

Stretchable energy storage devices are of great importance for the viable applications of wearable/stretchable electronics. Studies on stretchable energy storage devices, especially supercapacitors (SCs), have shown encouraging progress. However, challenges still remain in the pursuit of high specific capacitances and facile fabrication methods. Herein, we report a modular materials fabrication and assembly process for stretchable SCs. With a V2O5/PEDOT composite as the active material, the resulting stretchable SCs exhibited high areal specific capacitances up to 240 mF cm-2 and good capacitance retention at a strain of 50%. To demonstrate the facile assembly process, a stretchable wristband was fabricated by simply assembling SC cells in series to deliver a voltage higher than 2 V. Charging the wristband with a triboelectric nanogenerator (TENG) to light an LED was further demonstrated, indicating the potential to integrate our SCs with environmental energy harvesters for self-powered stretchable devices.

KSC-2009-2231

NASA Image and Video Library

2009-03-20

CAPE CANAVERAL, Fla. –The cars on the NASA Railroad are separated for different destinations at NASA's Kennedy Space Center in Florida. They carry Ares I-X segments. One of the cars is going to the Rotation, Processing and Surge Facility. The four reusable motor segments and the nozzle exit cone, manufactured by the Ares I first-stage prime contractor Alliant Techsystems Inc., or ATK, departed Utah March 12 on the seven-day, cross-country trip to Florida. The segments will be delivered to Kennedy's Rotation, Processing and Surge Facility for final processing and integration. The booster used for the Ares I-X launch is being modified by adding new forward structures and a fifth segment simulator. The motor is the final hardware needed for the rocket's upcoming test flight this summer. The stacking operations are scheduled to begin in the Vehicle Assembly Building in April. Photo credit: NASA/Jack Pfaller

KSC-2009-2230

NASA Image and Video Library

2009-03-20

CAPE CANAVERAL, Fla. – The NASA Railroad leaves four of the cars with Ares I-X segments at Suspect siding on NASA's Kennedy Space Center in Florida and continues on with the remaining car to the Rotation, Processing and Surge Facility. The four reusable motor segments and the nozzle exit cone, manufactured by the Ares I first-stage prime contractor Alliant Techsystems Inc., or ATK, departed Utah March 12 on the seven-day, cross-country trip to Florida. The segments will be delivered to Kennedy's Rotation, Processing and Surge Facility for final processing and integration. The booster used for the Ares I-X launch is being modified by adding new forward structures and a fifth segment simulator. The motor is the final hardware needed for the rocket's upcoming test flight this summer. The stacking operations are scheduled to begin in the Vehicle Assembly Building in April. Photo credit: NASA/Jack Pfaller

Cryogenic Fluid Management Facility

NASA Technical Reports Server (NTRS)

Eberhardt, R. N.; Bailey, W. J.; Symons, E. P.; Kroeger, E. W.

1984-01-01

The Cryogenic Fluid Management Facility (CFMF) is a reusable test bed which is designed to be carried into space in the Shuttle cargo bay to investigate systems and technologies required to efficiently and effectively manage cryogens in space. The facility hardware is configured to provide low-g verification of fluid and thermal models of cryogenic storage, transfer concepts and processes. Significant design data and criteria for future subcritical cryogenic storage and transfer systems will be obtained. Future applications include space-based and ground-based orbit transfer vehicles (OTV), space station life support, attitude control, power and fuel depot supply, resupply tankers, external tank (ET) propellant scavenging, space-based weapon systems and space-based orbit maneuvering vehicles (OMV). This paper describes the facility and discusses the cryogenic fluid management technology to be investigated. A brief discussion of the integration issues involved in loading and transporting liquid hydrogen within the Shuttle cargo bay is also included.

Video Analysis in Multi-Intelligence

DOE Office of Scientific and Technical Information (OSTI.GOV)

Key, Everett Kiusan; Van Buren, Kendra Lu; Warren, Will

This is a project which was performed by a graduated high school student at Los Alamos National Laboratory (LANL). The goal of the Multi-intelligence (MINT) project is to determine the state of a facility from multiple data streams. The data streams are indirect observations. The researcher is using DARHT (Dual-Axis Radiographic Hydrodynamic Test Facility) as a proof of concept. In summary, videos from the DARHT facility contain a rich amount of information. Distribution of car activity can inform us about the state of the facility. Counting large vehicles shows promise as another feature for identifying the state of operations. Signalmore » processing techniques are limited by the low resolution and compression of the videos. We are working on integrating these features with features obtained from other data streams to contribute to the MINT project. Future work can pursue other observations, such as when the gate is functioning or non-functioning.« less

Evaluating the relative impacts of operational and financial factors on the competitiveness of an algal biofuel production facility.

PubMed

Hise, Adam M; Characklis, Gregory W; Kern, Jordan; Gerlach, Robin; Viamajala, Sridhar; Gardner, Robert D; Vadlamani, Agasteswar

2016-11-01

Algal biofuels are becoming more economically competitive due to technological advances and government subsidies offering tax benefits and lower cost financing. These factors are linked, however, as the value of technical advances is affected by modeling assumptions regarding the growth conditions, process design, and financing of the production facility into which novel techniques are incorporated. Two such techniques, related to algal growth and dewatering, are evaluated in representative operating and financing scenarios using an integrated techno-economic model. Results suggest that these techniques can be valuable under specified conditions, but also that investment subsidies influence cost competitive facility design by incentivizing development of more capital intensive facilities (e.g., favoring hydrothermal liquefaction over transesterification-based facilities). Evaluating novel techniques under a variety of operational and financial scenarios highlights the set of site-specific conditions in which technical advances are most valuable, while also demonstrating the influence of subsidies linked to capital intensity. Copyright © 2016 Elsevier Ltd. All rights reserved.

Total Quality Management in Space Shuttle Main Engine manufacturing

NASA Technical Reports Server (NTRS)

Ding, J.

1992-01-01

The Total Quality Management (TQM) philosophy developed in the Marshall Space Flight Center (MSFC) is briefly reviewed and the ongoing TQM implementation effort which is being pursued through the continuous improvement (CI) process is discussed. TQM is based on organizational excellence which integrates the new supportive culture with the technical tools necessary to identify, assess, and correct manufacturing processes. Particular attention is given to the prime contractor's change to the organizational excellence management philosophy in SSME manufacturing facilities.

The IBA Easy-E-Beam™ Integrated Processing System

NASA Astrophysics Data System (ADS)

Cleland, Marshall R.; Galloway, Richard A.; Lisanti, Thomas F.

2011-06-01

IBA Industrial Inc., (formerly known as Radiation Dynamics, Inc.) has been making high-energy and medium-energy, direct-current proton and electron accelerators for research and industrial applications for many years. Some industrial applications of high-power electron accelerators are the crosslinking of polymeric materials and products, such as the insulation on electrical wires, multi-conductor cable jackets, heat-shrinkable plastic tubing and film, plastic pipe, foam and pellets, the partial curing of rubber sheet for automobile tire components, and the sterilization of disposable medical devices. The curing (polymerization and crosslinking) of carbon and glass fiber-reinforced composite plastic parts, the preservation of foods and the treatment of waste materials are attractive possibilities for future applications. With electron energies above 1.0 MeV, the radiation protection for operating personnel is usually provided by surrounding the accelerator facility with thick concrete walls. With lower energies, steel and lead panels can be used, which are substantially thinner and more compact than the equivalent concrete walls. IBA has developed a series of electron processing systems called Easy-e-Beam™ for the medium energy range from 300 keV to 1000 keV. These systems include the shielding as an integral part of a complete radiation processing facility. The basic concepts of the electron accelerator, the product processing equipment, the programmable control system, the configuration of the radiation shielding and some performance characteristics are described in this paper.

ENGINEERED NEAR SURFACE DISPOSAL FACILITY OF THE INDUSTRIAL COMPLEX FOR SOLID RADWASTE MANAGEMENT AT CHERNOBYL NUCLEAR POWER PLANT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ziehm, Ronny; Pichurin, Sergey Grigorevich

2003-02-27

As a part of the turnkey project ''Industrial Complex for Solid Radwaste Management (ICSRM) at the Chernobyl Nuclear Power Plant (ChNPP)'' an Engineered Near Surface Disposal Facility (ENSDF, LOT 3) will be built on the VEKTOR site within the 30 km Exclusion Zone of the ChNPP. This will be performed by RWE NUKEM GmbH, Germany, and it governs the design, licensing support, fabrication, assembly, testing, inspection, delivery, erection, installation and commissioning of the ENSDF. The ENSDF will receive low to intermediate level, short lived, processed/conditioned wastes from the ICSRM Solid Waste Processing Facility (SWPF, LOT 2), the ChNPP Liquid Radwastemore » Treatment Plant (LRTP) and the ChNPP Interim Storage Facility for RBMK Fuel Assemblies (ISF). The ENSDF has a capacity of 55,000 m{sup 3}. The primary functions of the ENSDF are: to receive, monitor and record waste packages, to load the waste packages into concrete disposal units, to enable capping and closure of the disposal unit s, to allow monitoring following closure. The ENSDF comprises the turnkey installation of a near surface repository in the form of an engineered facility for the final disposal of LILW-SL conditioned in the ICSRM SWPF and other sources of Chernobyl waste. The project has to deal with the challenges of the Chernobyl environment, the fulfillment of both Western and Ukrainian standards, and the installation and coordination of an international project team. It will be shown that proven technologies and processes can be assembled into a unique Management Concept dealing with all the necessary demands and requirements of a turnkey project. The paper emphasizes the proposed concepts for the ENSDF and their integration into existing infrastructure and installations of the VEKTOR site. Further, the paper will consider the integration of Western and Ukrainian Organizations into a cohesive project team and the requirement to guarantee the fulfillment of both Western standards and Ukrainian regulations and licensing requirements. The paper provides information on the output of the Detail Design and will reflect the progress of the design work.« less

Understanding Risk Tolerance and Building an Effective Safety Culture

NASA Technical Reports Server (NTRS)

Loyd, David

2018-01-01

Estimates range from 65-90 percent of catastrophic mishaps are due to human error. NASA's human factors-related mishaps causes are estimated at approximately 75 percent. As much as we'd like to error-proof our work environment, even the most automated and complex technical endeavors require human interaction... and are vulnerable to human frailty. Industry and government are focusing not only on human factors integration into hazardous work environments, but also looking for practical approaches to cultivating a strong Safety Culture that diminishes risk. Industry and government organizations have recognized the value of monitoring leading indicators to identify potential risk vulnerabilities. NASA has adapted this approach to assess risk controls associated with hazardous, critical, and complex facilities. NASA's facility risk assessments integrate commercial loss control, OSHA (Occupational Safety and Health Administration) Process Safety, API (American Petroleum Institute) Performance Indicator Standard, and NASA Operational Readiness Inspection concepts to identify risk control vulnerabilities.

Space station needs, attributes, and architectural options study. Volume 1: Missions and requirements

NASA Technical Reports Server (NTRS)

1983-01-01

Science and applications, NOAA environmental observation, commercial resource observations, commercial space processing, commercial communications, national security, technology development, and GEO servicing are addressed. Approach to time phasing of mission requirements, system sizing summary, time-phased user mission payload support, space station facility requirements, and integrated time-phased system requirements are also addressed.

Autoclave Meltout of Cast Explosives

DTIC Science & Technology

1996-08-22

various tanks , kettles , and pelletizing equipment a usable product was recovered. This process creates large amounts of pink water requiring...vacuum treatment melt kettles , flaker belts, and improved material handling equipment in an integrated system. During the 1976/1977 period, AED...McAlester Army Ammo Plant , Oklahoma, to discuss proposed workload and inspect available facilities and equipment . Pilot model production and testing

Writing Material in Chemical Physics Research: The Laboratory Notebook as Locus of Technical and Textual Integration

ERIC Educational Resources Information Center

Wickman, Chad

2010-01-01

This article, drawing on ethnographic study in a chemical physics research facility, explores how notebooks are used and produced in the conduct of laboratory science. Data include written field notes of laboratory activity; visual documentation of "in situ" writing processes; analysis of inscriptions, texts, and material artifacts produced in the…

An integrated approach for monitoring efficiency and investments of activated sludge-based wastewater treatment plants at large spatial scale.

PubMed

De Gisi, Sabino; Sabia, Gianpaolo; Casella, Patrizia; Farina, Roberto

2015-08-01

WISE, the Water Information System for Europe, is the web-portal of the European Commission (EU) that disseminates the quality state of the receiving water bodies and the efficiency of the municipal wastewater treatment plants (WWTPs) in order to monitor advances in the application of both the Water Framework Directive (WFD) as well as the Urban Wastewater Treatment Directive (UWWTD). With the intention to develop WISE applications, the aim of the work was to define and apply an integrated approach capable of monitoring the efficiency and investments of activated sludge-based WWTPs located in a large spatial area, providing the following outcomes useful to the decision-makers: (i) the identification of critical facilities and their critical processes by means of a Performance Assessment System (PAS), (ii) the choice of the most suitable upgrading actions, through a scenario analysis. (iii) the assessment of the investment costs to upgrade the critical WWTPs and (iv) the prioritization of the critical facilities by means of a multi-criteria approach which includes the stakeholders involvement, along with the integration of some technical, environmental, economic and health aspects. The implementation of the proposed approach to a high number of municipal WWTPs highlighted how the PAS developed was able to identify critical processes with a particular effectiveness in identifying the critical nutrient removal ones. In addition, a simplified approach that considers the cost related to a basic-configuration and those for the WWTP integration, allowed to link the critical processes identified and the investment costs. Finally, the questionnaire for the acquisition of data such as that provided by the Italian Institute of Statistics, the PAS defined and the database on the costs, if properly adapted, may allow for the extension of the integrated approach on an EU-scale by providing useful information to water utilities as well as institutions. Copyright © 2015 Elsevier B.V. All rights reserved.

Universal microfluidic automaton for autonomous sample processing: application to the Mars Organic Analyzer.

PubMed

Kim, Jungkyu; Jensen, Erik C; Stockton, Amanda M; Mathies, Richard A

2013-08-20

A fully integrated multilayer microfluidic chemical analyzer for automated sample processing and labeling, as well as analysis using capillary zone electrophoresis is developed and characterized. Using lifting gate microfluidic control valve technology, a microfluidic automaton consisting of a two-dimensional microvalve cellular array is fabricated with soft lithography in a format that enables facile integration with a microfluidic capillary electrophoresis device. The programmable sample processor performs precise mixing, metering, and routing operations that can be combined to achieve automation of complex and diverse assay protocols. Sample labeling protocols for amino acid, aldehyde/ketone and carboxylic acid analysis are performed automatically followed by automated transfer and analysis by the integrated microfluidic capillary electrophoresis chip. Equivalent performance to off-chip sample processing is demonstrated for each compound class; the automated analysis resulted in a limit of detection of ~16 nM for amino acids. Our microfluidic automaton provides a fully automated, portable microfluidic analysis system capable of autonomous analysis of diverse compound classes in challenging environments.

High-autonomy control of space resource processing plants

NASA Technical Reports Server (NTRS)

Schooley, Larry C.; Zeigler, Bernard P.; Cellier, Francois E.; Wang, Fei-Yue

1993-01-01

A highly autonomous intelligent command/control architecture has been developed for planetary surface base industrial process plants and Space Station Freedom experimental facilities. The architecture makes use of a high-level task-oriented mode with supervisory control from one or several remote sites, and integrates advanced network communications concepts and state-of-the-art man/machine interfaces with the most advanced autonomous intelligent control. Attention is given to the full-dynamics model of a Martian oxygen-production plant, event-based/fuzzy-logic process control, and fault management practices.

Major system acquisitions process (A-109)

NASA Technical Reports Server (NTRS)

Saric, C.

1991-01-01

The Major System examined is a combination of elements (hardware, software, facilities, and services) that function together to produce capabilities required to fulfill a mission need. The system acquisition process is a sequence of activities beginning with documentation of mission need and ending with introduction of major system into operational use or otherwise successful achievement of program objectives. It is concluded that the A-109 process makes sense and provides a systematic, integrated management approach along with appropriate management level involvement and innovative and 'best ideas' from private sector in satisfying mission needs.

Using a qualitative approach for understanding hospital-affiliated integrated clinical and fitness facilities: characteristics and members' experiences.

PubMed

Yang, Jingzhen; Kingsbury, Diana; Nichols, Matthew; Grimm, Kristin; Ding, Kele; Hallam, Jeffrey

2015-06-19

With health care shifting away from the traditional sick care model, many hospitals are integrating fitness facilities and programs into their clinical services in order to support health promotion and disease prevention at the community level. Through a series of focus groups, the present study assessed characteristics of hospital-affiliated integrated facilities located in Northeast Ohio, United States and members' experiences with respect to these facilities. Adult members were invited to participate in a focus group using a recruitment flyer. A total of 6 focus groups were conducted in 2013, each lasting one hour, ranging from 5 to 12 participants per group. The responses and discussions were recorded and transcribed verbatim, then analyzed independently by research team members. Major themes were identified after consensus was reached. The participants' average age was 57, with 56.8% currently under a doctor's care. Four major themes associated with integrated facilities and members' experiences emerged across the six focus groups: 1) facility/program, 2) social atmosphere, 3) provider, and 4) member. Within each theme, several sub-themes were also identified. A key feature of integrated facilities is the availability of clinical and fitness services "under one roof". Many participants remarked that they initially attended physical therapy, becoming members of the fitness facility afterwards, or vice versa. The participants had favorable views of and experiences with the superior physical environment and atmosphere, personal attention, tailored programs, and knowledgeable, friendly, and attentive staff. In particular, participants favored the emphasis on preventive care and the promotion of holistic health and wellness. These results support the integration of wellness promotion and programming with traditional medical care and call for the further evaluation of such a model with regard to participants' health outcomes.

Author Contribution to the Pu Handbook II: Chapter 37 LLNL Integrated Sample Preparation Glovebox (TEM) Section

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wall, Mark A.

The development of our Integrated Actinide Sample Preparation Laboratory (IASPL) commenced in 1998 driven by the need to perform transmission electron microscopy studies on naturally aged plutonium and its alloys looking for the microstructural effects of the radiological decay process (1). Remodeling and construction of a laboratory within the Chemistry and Materials Science Directorate facilities at LLNL was required to turn a standard radiological laboratory into a Radiological Materials Area (RMA) and Radiological Buffer Area (RBA) containing type I, II and III workplaces. Two inert atmosphere dry-train glove boxes with antechambers and entry/exit fumehoods (Figure 1), having a baseline atmospheremore » of 1 ppm oxygen and 1 ppm water vapor, a utility fumehood and a portable, and a third double-walled enclosure have been installed and commissioned. These capabilities, along with highly trained technical staff, facilitate the safe operation of sample preparation processes and instrumentation, and sample handling while minimizing oxidation or corrosion of the plutonium. In addition, we are currently developing the capability to safely transfer small metallographically prepared samples to a mini-SEM for microstructural imaging and chemical analysis. The gloveboxes continue to be the most crucial element of the laboratory allowing nearly oxide-free sample preparation for a wide variety of LLNL-based characterization experiments, which includes transmission electron microscopy, electron energy loss spectroscopy, optical microscopy, electrical resistivity, ion implantation, X-ray diffraction and absorption, magnetometry, metrological surface measurements, high-pressure diamond anvil cell equation-of-state, phonon dispersion measurements, X-ray absorption and emission spectroscopy, and differential scanning calorimetry. The sample preparation and materials processing capabilities in the IASPL have also facilitated experimentation at world-class facilities such as the Advanced Photon Source at Argonne National Laboratory, the European Synchrotron Radiation Facility in Grenoble, France, the Stanford Synchrotron Radiation Facility, the National Synchrotron Light Source at Brookhaven National Laboratory, the Advanced Light Source at Lawrence Berkeley National Laboratory, and the Triumph Accelerator in Canada.« less

Electromagnetic mixed waste processing system for asbestos decontamination

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kasevich, R.S.; Vaux, W.; Ulerich, N.

The overall objective of this three-phase program is to develop an integrated process for treating asbestos-containing material that is contaminated with radioactive and hazardous constituents. The integrated process will attempt to minimize processing and disposal costs. The objectives of Phase 1 were to establish the technical feasibility of asbestos decomposition, inorganic radionuclide nd heavy metal removal, and organic volatilization. Phase 1 resulted in the successful bench-scale demonstration of the elements required to develop a mixed waste treatment process for asbestos-containing material (ACM) contaminated with radioactive metals, heavy metals, and organics. Using the Phase 1 data, a conceptual process was developed.more » The Phase 2 program, currently in progress, is developing an integrated system design for ACM waste processing. The Phase 3 program will target demonstration of the mixed waste processing system at a DOE facility. The electromagnetic mixed waste processing system employs patented technologies to convert DOE asbestos to a non-hazardous, radionuclide-free, stable waste. The dry, contaminated asbestos is initially heated with radiofrequency energy to remove organic volatiles. Second,the radionuclides are removed by solvent extraction coupled with ion exchange solution treatment. Third, the ABCOV method converts the asbestos to an amorphous silica suspension at low temperature (100{degrees}C). Finally the amorphous silica is solidified for disposal.« less

Numbers, systems, people: how interactions influence integration. Insights from case studies of HIV and reproductive health services delivery in Kenya

PubMed Central

Mayhew, Susannah H; Warren, Charlotte E; Collumbien, Martine; Ndwiga, Charity; Mutemwa, Richard; Lut, Irina; Colombini, Manuela; Vassall, Anna

2017-01-01

Abstract Drawing on rich data from the Integra evaluation of integrated HIV and reproductive-health services, we explored the interaction of systems hardware and software factors to explain why some facilities were able to implement and sustain integrated service delivery while others were not. This article draws on detailed mixed-methods data for four case-study facilities offering reproductive-health and HIV services between 2009 and 2013 in Kenya: (i) time-series client flow, tracking service uptake for 8841 clients; (ii) structured questionnaires with 24 providers; (iii) in-depth interviews with 17 providers; (iv) workload and facility data using a periodic activity review and cost-instruments; and (v) contextual data on external activities related to integration in study sites. Overall, our findings suggested that although structural factors like stock-outs, distribution of staffing and workload, rotation of staff can affect how integrated care is provided, all these factors can be influenced by staff themselves: both frontline and management. Facilities where staff displayed agency of decision making, worked as a team to share workload and had management that supported this, showed better integration delivery and staff were able to overcome some structural deficiencies to enable integrated care. Poor-performing facilities had good structural integration, but staff were unable to utilize this because they were poorly organized, unsupported or teams were dysfunctional. Conscientious objection and moralistic attitudes were also barriers. Integra has demonstrated that structural integration is not sufficient for integrated service delivery. Rather, our case studies show that in some cases excellent leadership and peer-teamwork enabled facilities to perform well despite resource shortages. The ability to provide support for staff to work flexibly to deliver integrated services and build resilient health systems to meet changing needs is particularly relevant as health systems face challenges of changing burdens of disease, climate change, epidemic outbreaks and more. PMID:29194544

Fermentation process for the production of organic acids

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hermann, Theron; Reinhardt, James; Yu, Xiaohui

This invention relates to improvements in the fermentation process used in the production of organic acids from biological feedstock using bacterial catalysts. The improvements in the fermentation process involve providing a fermentation medium comprising an appropriate form of inorganic carbon, an appropriate amount of aeration and a biocatalyst with an enhanced ability to uptake and assimilate the inorganic carbon into the organic acids. This invention also provides, as a part of an integrated fermentation facility, a novel process for producing a solid source of inorganic carbon by sequestering carbon released from the fermentation in an alkali solution.

Effect of a package of integrated demand- and supply-side interventions on facility delivery rates in rural Bangladesh: Implications for large-scale programs

PubMed Central

Choudhury, Aziz Ahmed; Khanam, Rasheda; Moin, Syed Mamun Ibne; Ahmed, Salahuddin; Begum, Nazma; Shoma, Nurun Naher; Quaiyum, Md Abdul; Baqui, Abdullah H.

2017-01-01

Background According to the Bangladesh Demographic and Health Survey 2014, only approximately 37 percent of women deliver in a health facility. Among the eight administrative divisions of Bangladesh, the facility delivery rate is lowest in the Sylhet division (22.6 percent) where we assessed the effect of integrated supply- and demand-side interventions on the facility-based delivery rate. Methods Population-based cohort data of pregnant women from an ongoing maternal and newborn health improvement study being conducted in a population of ~120,000 in Sylhet district were used. The study required collection and processing of biological samples immediately after delivery. Therefore, the project assembled various strategies to increase institutional delivery rates. The supply-side intervention included capacity expansion of the health facilities through service provider refresher training, 24/7 service coverage, additions of drugs and supplies, and incentives to the providers. The demand-side component involved financial incentives to cover expenses, a provision of emergency transport, and referral support to a tertiary-level hospital. We conducted a before-and-after observational study to assess the impact of the intervention in a total of 1,861 deliveries between December 2014 and November 2016. Results Overall, implementation of the intervention package was associated with 52.6 percentage point increase in the proportions of facility-based deliveries from a baseline rate of 25.0 percent to 77.6 percent in 24 months. We observed lower rates of institutional deliveries when only supply-side interventions were implemented. The proportion rose to 47.1 percent and continued increasing when the project emphasized addressing the financial barriers to accessing obstetric care in a health facility. Conclusions An integrated supply- and demand-side intervention was associated with a substantial increase in institutional delivery. The package can be tailored to identify which combination of interventions may produce the optimum result and be scaled. Rigorous implementation research studies are needed to draw confident conclusions and to provide information about the costs, feasibility for scale-up and sustainability. PMID:29073229

A second generation 50 Mbps VLSI level zero processing system prototype

NASA Technical Reports Server (NTRS)

Harris, Jonathan C.; Shi, Jeff; Speciale, Nick; Bennett, Toby

1994-01-01

Level Zero Processing (LZP) generally refers to telemetry data processing functions performed at ground facilities to remove all communication artifacts from instrument data. These functions typically include frame synchronization, error detection and correction, packet reassembly and sorting, playback reversal, merging, time-ordering, overlap deletion, and production of annotated data sets. The Data Systems Technologies Division (DSTD) at Goddard Space Flight Center (GSFC) has been developing high-performance Very Large Scale Integration Level Zero Processing Systems (VLSI LZPS) since 1989. The first VLSI LZPS prototype demonstrated 20 Megabits per second (Mbp's) capability in 1992. With a new generation of high-density Application-specific Integrated Circuits (ASIC) and a Mass Storage System (MSS) based on the High-performance Parallel Peripheral Interface (HiPPI), a second prototype has been built that achieves full 50 Mbp's performance. This paper describes the second generation LZPS prototype based upon VLSI technologies.

Continuous Manufacturing of Recombinant Therapeutic Proteins: Upstream and Downstream Technologies.

PubMed

Patil, Rohan; Walther, Jason

2017-03-07

Continuous biomanufacturing of recombinant therapeutic proteins offers several potential advantages over conventional batch processing, including reduced cost of goods, more flexible and responsive manufacturing facilities, and improved and consistent product quality. Although continuous approaches to various upstream and downstream unit operations have been considered and studied for decades, in recent years interest and application have accelerated. Researchers have achieved increasingly higher levels of process intensification, and have also begun to integrate different continuous unit operations into larger, holistically continuous processes. This review first discusses approaches for continuous cell culture, with a focus on perfusion-enabling cell separation technologies including gravitational, centrifugal, and acoustic settling, as well as filtration-based techniques. We follow with a review of various continuous downstream unit operations, covering categories such as clarification, chromatography, formulation, and viral inactivation and filtration. The review ends by summarizing case studies of integrated and continuous processing as reported in the literature.

Knowledge Management tools integration within DLR's concurrent engineering facility

NASA Astrophysics Data System (ADS)

Lopez, R. P.; Soragavi, G.; Deshmukh, M.; Ludtke, D.

The complexity of space endeavors has increased the need for Knowledge Management (KM) tools. The concept of KM involves not only the electronic storage of knowledge, but also the process of making this knowledge available, reusable and traceable. Establishing a KM concept within the Concurrent Engineering Facility (CEF) has been a research topic of the German Aerospace Centre (DLR). This paper presents the current KM tools of the CEF: the Software Platform for Organizing and Capturing Knowledge (S.P.O.C.K.), the data model Virtual Satellite (VirSat), and the Simulation Model Library (SimMoLib), and how their usage improved the Concurrent Engineering (CE) process. This paper also exposes the lessons learned from the introduction of KM practices into the CEF and elaborates a roadmap for the further development of KM in CE activities at DLR. The results of the application of the Knowledge Management tools have shown the potential of merging the three software platforms with their functionalities, as the next step towards the fully integration of KM practices into the CE process. VirSat will stay as the main software platform used within a CE study, and S.P.O.C.K. and SimMoLib will be integrated into VirSat. These tools will support the data model as a reference and documentation source, and as an access to simulation and calculation models. The use of KM tools in the CEF aims to become a basic practice during the CE process. The settlement of this practice will result in a much more extended knowledge and experience exchange within the Concurrent Engineering environment and, consequently, the outcome of the studies will comprise higher quality in the design of space systems.

Multiloop Integral System Test (MIST): MIST Facility Functional Specification

DOE Office of Scientific and Technical Information (OSTI.GOV)

Habib, T F; Koksal, C G; Moskal, T E

1991-04-01

The Multiloop Integral System Test (MIST) is part of a multiphase program started in 1983 to address small-break loss-of-coolant accidents (SBLOCAs) specific to Babcock and Wilcox designed plants. MIST is sponsored by the US Nuclear Regulatory Commission, the Babcock Wilcox Owners Group, the Electric Power Research Institute, and Babcock and Wilcox. The unique features of the Babcock and Wilcox design, specifically the hot leg U-bends and steam generators, prevented the use of existing integral system data or existing integral facilities to address the thermal-hydraulic SBLOCA questions. MIST was specifically designed and constructed for this program, and an existing facility --more » the Once Through Integral System (OTIS) -- was also used. Data from MIST and OTIS are used to benchmark the adequacy of system codes, such as RELAP5 and TRAC, for predicting abnormal plant transients. The MIST Functional Specification documents as-built design features, dimensions, instrumentation, and test approach. It also presents the scaling basis for the facility and serves to define the scope of work for the facility design and construction. 13 refs., 112 figs., 38 tabs.« less

David Florida Laboratory Thermal Vacuum Data Processing System

NASA Technical Reports Server (NTRS)

Choueiry, Elie

1994-01-01

During 1991, the Space Simulation Facility conducted a survey to assess the requirements and analyze the merits for purchasing a new thermal vacuum data processing system for its facilities. A new, integrated, cost effective PC-based system was purchased which uses commercial off-the-shelf software for operation and control. This system can be easily reconfigured and allows its users to access a local area network. In addition, it provides superior performance compared to that of the former system which used an outdated mini-computer and peripheral hardware. This paper provides essential background on the old data processing system's features, capabilities, and the performance criteria that drove the genesis of its successor. This paper concludes with a detailed discussion of the thermal vacuum data processing system's components, features, and its important role in supporting our space-simulation environment and our capabilities for spacecraft testing. The new system was tested during the ANIK E spacecraft test, and was fully operational in November 1991.

Resistivity of Carbon-Carbon Composites Halved

NASA Technical Reports Server (NTRS)

Gaier, James R.

2004-01-01

Carbon-carbon composites have become the material of choice for applications requiring strength and stiffness at very high temperatures (above 2000 C). These composites comprise carbon or graphite fibers embedded in a carbonized or graphitized matrix. In some applications, such as shielding sensitive electronics in very high temperature environments, the performance of these materials would be improved by lowering their electrical resistivity. One method to lower the resistivity of the composites is to lower the resistivity of the graphite fibers, and a proven method to accomplish that is intercalation. Intercalation is the insertion of guest atoms or molecules into a host lattice. In this study the host fibers were highly graphitic pitch-based graphite fibers, or vapor-grown carbon fibers (VGCF), and the intercalate was bromine. Intercalation compounds of graphite are generally thought of as being only metastable, but it has been shown that the residual bromine graphite fiber intercalation compound is remarkably stable, resisting decomposition even at temperatures at least as high as 1000 C. The focus of this work was to fabricate composite preforms, determine whether the fibers they were made from were still intercalated with bromine after processing, and determine the effect on composite resistivity. It was not expected that the resistivity would be lowered as dramatically as with graphite polymer composites because the matrix itself would be much more conductive, but it was hoped that the gains would be substantial enough to warrant its use in high-performance applications. In a collaborative effort supporting a Space Act Agreement between the NASA Glenn Research Center and Applied Sciences, Inc. (Cedarville, OH), laminar preforms were fabricated with pristine and bromine-intercalated pitch-based fibers (P100 and P100-Br) and VGCF (Pyro I and Pyro I-Br). The green preforms were carbonized at 1000 C and then heat treated to 3000 C. To determine whether the fibers in the samples were still intercalated after composite fabrication, they were subjected to X-ray diffraction. The composites containing intercalated graphite fibers showed much higher background scatter than that of pristine fibers, indicating the presence of bromine in the samples. More importantly, faint features indicative of intercalation were visible in the diffraction pattern, showing that the fibers were still intercalated.