Sample records for integrated system dris

  1. Woody tissue analysis using an element ratio technique (DRIS)

    Treesearch

    Kurt H. Riitters; L.F. Ohmann; D.F. Grigal

    1991-01-01

    The diagnosis and recommendation integrated system (DRIS) was used to describe the variation of 12 elements in woody tree tissue and balsam fir (Abies balsamae (L.) Mill.), sugar maple (Acer saccharum Marsh.), jack pine (Pinus banksiana Lamb.), red pine (Pinus resinosa alt.), and aspen (

  2. DRIS Analysis Identifies a Common Potassium Imbalance in Sweetgum Plantations

    Treesearch

    Mark D. Coleman; S.X. Chang; D.J. Robison

    2003-01-01

    DRIS (Diagnosis and Recommendation Integrated System) analysis was applied to fast-growing sweetgum (Liquidambar styraciflua L.) plantations in the southeast United States as a tool for nutrient diagnosis and fertilizer recommendations. First, standard foliar nutrient ratios for nitrogen (N), phosphorus (P), potassium (K), calcium (Ca), and...

  3. History of Nutrition: The Long Road Leading to the Dietary Reference Intakes for the United States and Canada123

    PubMed Central

    Murphy, Suzanne P; Yates, Allison A; Atkinson, Stephanie A; Barr, Susan I; Dwyer, Johanna

    2016-01-01

    The Dietary Reference Intakes (DRIs) are reference values to guide the planning and assessing of nutrient intakes in the United States and Canada. The DRI framework was conceptualized in 1994, and the first reports were issued from 1997–2004, based on work by expert panels and subcommittees under the guidance of the Food and Nutrition Board of the Institute of Medicine. Numerous conventions, challenges, and controversies were encountered during the process of defining and setting the DRIs, including the definition of the framework, the use of chronic disease endpoints, lack of data on requirements for children and youth, and methods for addressing nonessential bioactive substances with potential health benefits. DRIs may be used to plan and assess the nutrient intakes of both individuals and population groups, but the new paradigm particularly improved methods used for groups. It is now possible to estimate both the prevalence of inadequate intake and the prevalence of potentially excessive intake within a group. The DRIs have served as a potent influence on national nutrition policies, including those related to dietary guidance, food labeling, nutrition monitoring, food assistance programs, and military nutrition standards. Because of this important impact on nutrition policy, the DRIs must be based on the best possible and most up-to-date science. Unfortunately, no updates to specific DRIs are currently planned. Despite the long and challenging road that led to the current DRIs, it must not finish in a dead end. Monetary resources and political will are crucial to maintaining and continuously updating the DRIs. PMID:27180379

  4. Renin Angiotensin Aldosterone System Inhibitors in Hypertension: Is There Evidence for Benefit Independent of Blood Pressure Reduction?

    PubMed

    Bavishi, Chirag; Bangalore, Sripal; Messerli, Franz H

    The renin-angiotensin-aldosterone system (RAAS) plays a pivotal role in the pathogenesis of hypertension (HTN). Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs) are first line anti-HTN drug classes that are potent, effective and largely safe. Direct renin inhibitors (DRIs) have shown similar blood pressure (BP) reduction but more side effects. The efficacy of ACEIs and ARBs (for cardiovascular, cerebrovascular and renal protection) has been promoted to extend beyond what could be explained by BP reduction alone. In the current review, we will briefly discuss the (1) pathophysiology of renin-angiotensin-aldosterone system (RAAS) system, (2) clinical evidence for ACEIs, ARBs and DRIs in HTN, (3) comparison of ACEIs vs. ARBs and combination therapy, (4) role of RAAS inhibitors in specific patient populations, (5) safety profile of RAAS inhibitors, and (6) guideline recommendations and future perspectives. Closer scrutiny of outcome data shows little, if any, evidence that the efficacy of RAAS blockers in HTN extends beyond BP reduction. Copyright © 2016 Elsevier Inc. All rights reserved.

  5. Relationship Between Urinary Concentrations of Nine Water-soluble Vitamins and their Vitamin Intakes in Japanese Adult Males.

    PubMed

    Shibata, Katsumi; Hirose, Junko; Fukuwatari, Tsutomu

    2014-01-01

    Excess water-soluble vitamins are thought to be eliminated in the urine. We have reported a strong relationship between water-soluble vitamin intake and urinary excretion in females. The relationship, however, is not well understood in males. In the present experiment, 10 Japanese male subjects were given a standard Japanese diet for the first week. The subjects remained on the same diet, and a synthesized water-soluble vitamin mixture containing one time the Dietary Reference Intakes (DRIs) for Japanese was given for the second week, three times the DRIs for the third week, and six times the DRIs for the fourth week. Twenty-four-hour urine samples were collected each week. Urinary excretion levels for seven of the nine water-soluble vitamin levels, excluding vitamin B12 and folate, increased linearly and sharply in a dose-dependent manner. These results suggest that measuring urinary water-soluble vitamins can be good nutritional markers for assessing vitamin intakes in humans.

  6. Relationship Between Urinary Concentrations of Nine Water-soluble Vitamins and their Vitamin Intakes in Japanese Adult Males

    PubMed Central

    Shibata, Katsumi; Hirose, Junko; Fukuwatari, Tsutomu

    2014-01-01

    Excess water-soluble vitamins are thought to be eliminated in the urine. We have reported a strong relationship between water-soluble vitamin intake and urinary excretion in females. The relationship, however, is not well understood in males. In the present experiment, 10 Japanese male subjects were given a standard Japanese diet for the first week. The subjects remained on the same diet, and a synthesized water-soluble vitamin mixture containing one time the Dietary Reference Intakes (DRIs) for Japanese was given for the second week, three times the DRIs for the third week, and six times the DRIs for the fourth week. Twenty-four-hour urine samples were collected each week. Urinary excretion levels for seven of the nine water-soluble vitamin levels, excluding vitamin B12 and folate, increased linearly and sharply in a dose-dependent manner. These results suggest that measuring urinary water-soluble vitamins can be good nutritional markers for assessing vitamin intakes in humans. PMID:25210461

  7. Self-Reported Obstacles to Regular Dental Care among Information Technology Professionals.

    PubMed

    Reddy, L Swetha; Doshi, Dolar; Reddy, B Srikanth; Kulkarni, Suhas; Reddy, M Padma; Satyanarayana, D; Baldava, Pavan

    2016-10-01

    Good oral health is important for an individual as well as social well-being. Occupational stress and work exhaustion in Information Technology (IT) professionals may influence the oral health and oral health related quality of life. To assess and compare self-reported obstacles for regular dental care and dental visits among IT professionals based on age, gender, dental insurance and working days per week. A cross-sectional study was conducted among 1,017 IT professionals to assess the self-reported obstacles to regular oral health care in Hyderabad city, Telangana, India. The Dental Rejection of Innovation Scale (DRI-S) was employed in this study. Comparison between means of DRI-S based on variables was done using t-test and ANOVA. The association between variables and DRI-S was determined using Chi-square test. A total of 1017 participants comprising of 574 (56%) males and 443 (44%) females participated in the study. As age increased, a significant increase in mean DRI-S scores was seen for total and individual domains except for the "Situational" domain wherein higher mean score (9.42±2.5; p=0.0006) was observed among 30-39 years age group. Even though females reported higher mean scores for total and individual domains when compared to males, nevertheless significant difference was seen only for total (p=0.03) and "Lack of Knowledge" (p=0.001) domain. Self-reported obstacles to regular dental care was more with increasing age, increased number of working days per week, irregular dental visits and absence of dental insurance facility.

  8. Smokers report lower intake of key nutrients than nonsmokers, yet both fall short of meeting recommended intakes.

    PubMed

    Raatz, Susan K; Jahns, Lisa; Johnson, LuAnn K; Scheett, Angela; Carriquiry, Alicia; Lemieux, Andrine; Nakajima, Motohiro; al'Absi, Mustafa

    2017-09-01

    Smoking is a major risk factor in the development of preventable disease which may be due to a poorer diet and the reduced nutrient intake of smokers. Our objective was to compare and evaluate the reported intake of current smokers with that of nonsmokers among participants of a study evaluating stress and smoking. We hypothesized (1) that overall energy and nutrient intake would be reduced in smokers compared with nonsmokers and (2) that smokers would have increased noncompliance with Dietary Reference Intakes (DRIs). Men and women (smokers n=138, nonsmokers n=46) completed a 3-day diet record at baseline. Mean energy and nutrient intakes were stratified by smoking status and compared with DRI levels. The mean body mass index was 28.3±0.5kg/m 2 for smokers and 27.2±1.0kg/m 2 for nonsmokers. Compared with nonsmokers, the smokers reported lower intakes of energy, total polyunsaturated fatty acids, linolenic acid, docosahexaenoic acid, total sugars, calcium, iron, magnesium, phosphorus, potassium, vitamin C, riboflavin, niacin, pantothenic acid, vitamin B6, folate, vitamin A, and vitamin E. Smokers reported reduced compliance with the DRIs for iron, phosphorus, vitamin C, riboflavin, and folate compared with nonsmokers. Unlike other evaluations of smokers vs nonsmokers, we observed no difference in body weight between groups. Smokers and nonsmokers alike reported dietary intakes lower than the DRIs for many nutrients. However, the reported nutrient intake of the smokers was substantially lower than nonsmokers for key nutrients, and they were more likely to not comply with the DRIs for essential nutrients, placing them at increased risk of chronic disease. Published by Elsevier Inc.

  9. Are physical activity levels linked to nutrient adequacy? Implications for cancer risk.

    PubMed

    Csizmadi, Ilona; Kelemen, Linda E; Speidel, Thomas; Yuan, Yan; Dale, Laura C; Friedenreich, Christine M; Robson, Paula J

    2014-01-01

    Cancer prevention guidelines recommend a healthy body mass index, physical activity, and nutrient intake from food rather than supplements. Sedentary individuals may restrict energy intake to prevent weight gain and in so doing may compromise nutritional intake. We conducted a cross-sectional analysis to determine if adequacy of micronutrients is linked to physical activity levels (PALs) in healthy-weight adults. Tomorrow Project participants in Alberta, Canada (n = 5333), completed past-year diet and physical activity questionnaires. The percent meeting Dietary Reference Intakes (DRIs) was reported across low and high PAL groups, and the relation between PAL and percent achieved DRI was determined using multiple linear regression analyses. Overall, <50% of healthy-weight participants met DRIs for folate, calcium, and vitamin D. Percent achieved DRI increased linearly with increasing PAL in both genders (P < 0.01). A hypothetical increase in PAL from 1.4 to 1.9 was associated with a DRI that was 8%-13% higher for folate and vitamin C (men) and 5%-15% higher for calcium and iron (women). Healthy-weight adults at higher PALs appear more likely to meet DRIs for potential cancer-preventing nutrients. The benefits of higher PALs may extend beyond the usual benefits attributed to physical activity to include having a more favorable impact on nutrient adequacy.

  10. Water and Beverage Consumption among Children Aged 4-13 Years in Lebanon: Findings from a National Cross-Sectional Study.

    PubMed

    Jomaa, Lamis; Hwalla, Nahla; Constant, Florence; Naja, Farah; Nasreddine, Lara

    2016-09-08

    This study evaluates total water intake (TWI) from plain water, beverages and foods among Lebanese children and compares TWI to dietary reference intakes (DRIs). In a national cross-sectional survey, data on demographic, socioeconomic, anthropometric, and physical activity characteristics were obtained from 4 to 13-year-old children (n = 752). Food and beverage consumption patterns were assessed using a validated food-frequency questionnaire. TWI was estimated at 1651 mL/day, with beverages contributing 72% of the TWI compared to 28% from foods. Beverages with the highest contribution to TWI included plain water, fruit juice and soda. A significantly higher proportion of 9-13-year-old children failed to meet the DRIs compared to 4-8 years old (92%-98% vs. 74%). Gender differentials were observed with a significantly higher proportion of boys meeting the DRIs compared to girls. The water to energy ratio ranged between 0.84 and 0.87, which fell short of meeting the desirable recommendations. In addition, children from higher socioeconomic status had higher intakes of water from milk and bottled water, coupled with lower water intakes from sodas. The study findings show an alarming high proportion of Lebanese children failing to meet TWI recommendations, and call for culture-specific interventions to instill healthy fluid consumption patterns early in life.

  11. Maternal Dietary Nutrient Intake and Its Association  with Preterm Birth: A Case-control Study in Beijing,  China.

    PubMed

    Zhang, Yan; Zhou, Hong; Perkins, Anthony; Wang, Yan; Sun, Jing

    2017-03-01

    This study aimed to evaluate dietary nutrient intake among Chinese pregnant women by comparison with Chinese Dietary Reference Intakes (DRIs) and to explore the association between dietary nutrients and preterm birth. A case-control design was conducted in Beijing with 130 preterm delivery mothers in case group and 381 term delivery mothers in control group. Information on mothers' diet was collected using a food frequency questionnaire, and nutrients and energy intakes were subsequently calculated based on DRIs. Multivariate analysis of variance was used to compare the differences between term and preterm groups in relation to dietary nutrients. Dietary nutrient intakes were imbalanced in both groups compared with Chinese DRIs. Preterm delivery mothers had a lower level of fat and vitamin E intake than term delivery mothers (p < 0.05). Multivariate analysis showed lower vitamin E intake in preterm delivery mothers with a prepregnancy BMI < 18.5 kg/m2 (p < 0.05) and higher carbohydrate intake in preterm delivery mothers with prepregnancy BMI ≥ 24 kg/m2 (p < 0.05). An imbalanced diet in both groups and low level of dietary intakes of fat and vitamin E in preterm group suggest health education measures should be taken to improve the dietary quality of pregnant women, especially for those with an abnormal prepregnancy BMI.

  12. Water and Beverage Consumption among Children Aged 4–13 Years in Lebanon: Findings from a National Cross-Sectional Study

    PubMed Central

    Jomaa, Lamis; Hwalla, Nahla; Constant, Florence; Naja, Farah; Nasreddine, Lara

    2016-01-01

    This study evaluates total water intake (TWI) from plain water, beverages and foods among Lebanese children and compares TWI to dietary reference intakes (DRIs). In a national cross-sectional survey, data on demographic, socioeconomic, anthropometric, and physical activity characteristics were obtained from 4 to 13-year-old children (n = 752). Food and beverage consumption patterns were assessed using a validated food-frequency questionnaire. TWI was estimated at 1651 mL/day, with beverages contributing 72% of the TWI compared to 28% from foods. Beverages with the highest contribution to TWI included plain water, fruit juice and soda. A significantly higher proportion of 9–13-year-old children failed to meet the DRIs compared to 4–8 years old (92%–98% vs. 74%). Gender differentials were observed with a significantly higher proportion of boys meeting the DRIs compared to girls. The water to energy ratio ranged between 0.84 and 0.87, which fell short of meeting the desirable recommendations. In addition, children from higher socioeconomic status had higher intakes of water from milk and bottled water, coupled with lower water intakes from sodas. The study findings show an alarming high proportion of Lebanese children failing to meet TWI recommendations, and call for culture-specific interventions to instill healthy fluid consumption patterns early in life. PMID:27618092

  13. TECHNICAL NOTE: System for monitoring the evolution of the thermal expansion coefficient and autogenous deformation of hardening materials

    NASA Astrophysics Data System (ADS)

    Viviani, M.; Glisic, B.; Smith, I. F. C.

    2006-12-01

    This article presents an experimental system developed to determine the kinetic parameters of hardening materials. Kinetic parameters allow computation of the degree of reaction indices (DRIs). DRIs are used in predictive formulae for strength and are used to decouple the autogenous deformation (AD) and thermal deformation (TD). Although there are several methods to determine values for kinetic reaction parameters, most require extensive testing and large databases. A measurement system has been developed in order to determine kinetic parameters. The measurement system consists of optical fiber sensors embedded in specimens that are cured at varying temperatures and conditions. Sensors are used in pairs inside each specimen, and each pair has two deformation sensors that, aside from their axial stiffness, have the same characteristics. The study of the interaction between sensors and hardening material leads to establishment of a link between the deformations measured and the degree of reaction, by means of the newly developed concept of the equivalency point. The equivalency point is assumed to be an indicator of the degree of reaction and it allows the determination of the apparent activation energy (Ea) which defines the equivalent time. Equivalent time is a degree of reaction index (DRI) and it accounts for the combined effect of time and temperature in concrete. This new methodology has been used to predict the compressive strength and separate the AD and thermal expansion coefficient (TEC) in seven types of concrete. The measurement system allows gathering of data necessary for fast and efficient predictions. Due to its robustness and reduced dimensions it also has potential for in situ application.

  14. Dietary reference intakes for DHA and EPA.

    PubMed

    Kris-Etherton, Penny M; Grieger, Jessica A; Etherton, Terry D

    2009-01-01

    Various organizations worldwide have made dietary recommendations for eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and fish intake that are primarily for coronary disease risk reduction and triglyceride (TG) lowering. Recommendations also have been made for DHA intake for pregnant women, infants, and vegetarians/vegans. A Dietary Reference Intake (DRI), specifically, an Adequate Intake (AI), has been set for alpha-linolenic acid (ALA) by the Institute of Medicine (IOM) of The National Academies. This amount is based on an intake that supports normal growth and neural development and results in no nutrient deficiency. Although there is no DRI for EPA and DHA, the National Academies have recommended that approximately 10% of the Acceptable Macronutrient Distribution Range (AMDR) for ALA can be consumed as EPA and/or DHA. This recommendation represents current mean intake for EPA and DHA in the United States ( approximately 100mg/day), which is much lower than what many groups worldwide are currently recommending. Global recommendations for long-chain omega-3 fatty acids underscore the pressing need to establish DRIs for DHA and EPA because DRIs are recognized as the "official" standard by which federal agencies issue dietary guidance or policy directives for the health and well-being of individuals in the United States and Canada. Because of the many health benefits of DHA and EPA, it is important and timely that the National Academies establish DRIs for the individual long-chain (20 carbons or greater) omega-3 fatty acids.

  15. What's for lunch? An analysis of lunch menus in 83 urban and rural Oklahoma child-care centers providing all-day care to preschool children.

    PubMed

    Frampton, Ashley M; Sisson, Susan B; Horm, Diane; Campbell, Janis E; Lora, Karina; Ladner, Jennifer L

    2014-09-01

    More than half of 3- to 6-year-old children attend child-care centers. Dietary intakes of children attending child-care centers tend to fall short of Dietary Reference Intakes (DRIs). Our aim was to examine macro-/micronutrient content of child-care center menus, compare menus to one third of DRIs, and determine menu differences by population density. A stratified, random, geographically proportionate sample of Oklahoma child-care centers was obtained. Child-care centers providing all-day care for 2- to 5-year-old children were contacted to complete a telephone questionnaire and asked to send in that month's menus for the 3- to 4-year-old children. Overall means and standard deviations of the nutrient content of 5 days of lunch menus were calculated. Comparisons were made to both the 1- to 3-year-old and 4- to 8-year-old DRIs. One-sample t tests compared mean nutrient content of lunches to one third of the DRIs for the overall sample and urban/rural classification. Independent t tests compared nutrient content of urban and rural lunches. One hundred sixty-seven child-care centers were contacted; 83 completed the study (50% response). Menus provided statistically significantly insufficient carbohydrate, dietary fiber, iron, vitamin D, and vitamin E. Calcium was higher than the 1- to 3-year-old DRI, but lower than the 4- to 8-year-old DRI. Folate was higher than the 1- to 3-year-old DRI, but not different from the 4- to 8-year-old DRI. Sodium was higher than the DRI for both age groups. Thirty-four child-care centers (41%) were classified as urban and 49 (59%) as rural. Urban menus provided less than the 4- to 8-year-old DRI for folate, but rural child-care center menus did not. Oklahoma child-care center menus appear to provide adequate protein, magnesium, zinc, vitamin A, and vitamin C, but may be deficient in key nutrients required for good health and proper development in preschool-aged children. These issues can be addressed by including food and nutrition practitioners in the process to ensure child-care center menus are a useful resource and nutritionally appropriate for preschool children. Copyright © 2014 Academy of Nutrition and Dietetics. Published by Elsevier Inc. All rights reserved.

  16. Addressing the theoretical and clinical advantages of combination therapy with inhibitors of the renin-angiotensin-aldosterone system: antihypertensive effects and benefits beyond BP control.

    PubMed

    Ferrario, Carlos M

    2010-02-27

    This article reviews the importance of the renin-angiotensin-aldosterone system (RAAS) in the cardiometabolic continuum; presents the pros and cons of dual RAAS blockade with angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs); and examines the theoretical and practical benefits supporting the use of direct renin inhibitors (DRIs) in combination with ACEIs or ARBs. The author reviewed the literature for key publications related to the biochemical physiology of the RAAS and the pharmacodynamic effects of ACEIs, ARBs, and DRIs, with a particular focus on dual RAAS blockade with these drug classes. Although ACEI/ARB combination therapy produces modest improvement in BP, it has not resulted in the major improvements predicted given the importance of the RAAS across the cardiorenal disease continuum. This may reflect the fact that RAAS blockade with ACEIs and/or ARBs leads to exacerbated renin release through loss of negative-feedback inhibition, as well as ACE/aldosterone escape through RAAS and non-RAAS-mediated mechanisms. Plasma renin activity (PRA) is an independent predictor of morbidity and mortality, even for patients receiving ACEIs and ARBs. When used alone or in combination with ACEIs and ARBs, the DRI aliskiren effectively reduces PRA. Reductions in BP are greater with these combinations, relative to the individual components alone. It is possible that aliskiren plus either an ACEI or ARB may provide greater RAAS blockade than monotherapy with ACEIs or ARBs, and lead to additive improvement in BP and clinically important outcomes. Copyright 2009 Elsevier Inc. All rights reserved.

  17. Dietary reference intakes for vitamin D based on the revised 2010 dietary guidelines are not being met by children in Alberta, Canada.

    PubMed

    Munasinghe, Lalani L; Willows, Noreen; Yuan, Yan; Veugelers, Paul J

    2015-11-01

    Canadian children have been shown to be not meeting the revised (2010) dietary recommended intake (DRI) for vitamin D through diet alone. However, no study has evaluated whether diet and supplementation together are supporting Canadian children in meeting the DRIs for vitamin D intake. This study assessed the adequacy of vitamin D intake through diet and supplements among Albertan children and the determinants of meeting dietary guidelines. 2686 grade 5 students aged 10 to 11 years in Alberta, Canada were surveyed. We hypothesized that less than 50% of children would meet the DRI. Vitamin D intake from diet and supplements was assessed using a food frequency questionnaire. The adequacy of vitamin D intake was estimated using the Estimated Average Requirement (EAR) of 400 IU (International Units) and Recommended Dietary Allowance (RDA) of 600 IU. Random effect multiple logistic regression was used to identify correlates of meeting DRIs. Forty five percent of children met the EAR and 22% met the RDA for vitamin D. When vitamin D intake from diet alone was considered, only 16% and 2% met the EAR and RDA, respectively. Parental education, household income and physical activity were positively correlated with meeting DRIs, and students attending metropolitan area schools were more likely to meet the EAR than students attending rural area schools (OR = 1.28; P = .043). The majority of children did not meet the DRI for vitamin D. Health promotion strategies aiming to improve the vitamin D status of Albertan children are necessary given the importance of vitamin D for children's health and development. Crown Copyright © 2015. Published by Elsevier Inc. All rights reserved.

  18. Options for basing Dietary Reference Intakes (DRIs) on chronic disease endpoints: report from a joint US-/Canadian-sponsored working group123

    PubMed Central

    Yetley, Elizabeth A; MacFarlane, Amanda J; Greene-Finestone, Linda S; Garza, Cutberto; Ard, Jamy D; Atkinson, Stephanie A; Bier, Dennis M; Carriquiry, Alicia L; Harlan, William R; Hattis, Dale; King, Janet C; Krewski, Daniel; O’Connor, Deborah L; Prentice, Ross L; Rodricks, Joseph V; Wells, George A

    2017-01-01

    Dietary Reference Intakes (DRIs) are used in Canada and the United States in planning and assessing diets of apparently healthy individuals and population groups. The approaches used to establish DRIs on the basis of classical nutrient deficiencies and/or toxicities have worked well. However, it has proved to be more challenging to base DRI values on chronic disease endpoints; deviations from the traditional framework were often required, and in some cases, DRI values were not established for intakes that affected chronic disease outcomes despite evidence that supported a relation. The increasing proportions of elderly citizens, the growing prevalence of chronic diseases, and the persistently high prevalence of overweight and obesity, which predispose to chronic disease, highlight the importance of understanding the impact of nutrition on chronic disease prevention and control. A multidisciplinary working group sponsored by the Canadian and US government DRI steering committees met from November 2014 to April 2016 to identify options for addressing key scientific challenges encountered in the use of chronic disease endpoints to establish reference values. The working group focused on 3 key questions: 1) What are the important evidentiary challenges for selecting and using chronic disease endpoints in future DRI reviews, 2) what intake-response models can future DRI committees consider when using chronic disease endpoints, and 3) what are the arguments for and against continuing to include chronic disease endpoints in future DRI reviews? This report outlines the range of options identified by the working group for answering these key questions, as well as the strengths and weaknesses of each option. PMID:27927637

  19. Dietary Supplement Label Database (DSLD)

    Science.gov Websites

    Intakes (DRIs) Definitions Frequently Asked Questions (FAQ) Information Sources Release Notes Help Search full label derived information from dietary supplement products marketed in the U.S. with a Web-based user interface that provides ready access to label information. It was developed to serve the research

  20. Revision of dietary reference intakes for energy in preschool-age children

    USDA-ARS?s Scientific Manuscript database

    Dietary Reference Intakes (DRI) for energy aim to balance energy expenditure at a level of physical activity consistent with health and support adequate growth in children. DRIs were derived from total energy expenditure (TEE) measured by using the doubly labeled water (DLW) method; however, the dat...

  1. Efficiency and specificity of RAAS inhibitors in cardiovascular diseases: how to achieve better end-organ protection?

    PubMed

    Nehme, Ali; Zibara, Kazem

    2017-11-01

    RAAS, a major pharmacological target in cardiovascular medicine, is inhibited by pharmacological classes including angiotensin converting enzyme (ACE) inhibitors (ACEIs), angiotensin-II type 1 blockers (ARBs) and aldosterone receptors antagonists, in addition to the recently introduced direct renin inhibitors (DRIs). However, currently used RAAS inhibitors still cannot achieve their desired effects and are associated with certain drawbacks, such as adverse side effects, incomplete blockage of the system and poor end-organ protection. In this review, we discuss the efficiency and specificity of the current RAAS inhibitors and propose some recommendations for achieving better treatments with better end-organ protection.

  2. Dietary Intake and Associated Body Weight in Canadian Undergraduate Students Enrolled in Nutrition Education.

    PubMed

    Frehlich, Levi C; Eller, Lindsay K; Parnell, Jill A; Fung, Tak S; Reimer, Raylene A

    2017-01-01

    The primary purpose of this study was to describe dietary intakes among Canadian undergraduate students enrolled in an Introductory Nutrition course. A secondary objective was to determine food group servings associated with meeting more Dietary Reference Intakes (DRIs) of select nutrients and with a lower body mass index (BMI). Participants (n = 124, 20.7±3.2yrs) provided output from a 3-day dietary record and completed a physical activity/demographics questionnaire. Linear regression showed that the dietary intake associated with meeting the most DRIs included vegetables, fruits, protein foods, and dairy (p = 0.001). Protein foods were a positive predictor and fruit a negative predictor of BMI (p = 0.001 and p = 0.023 respectively). Males consumed more grains (p = 0.001), dairy (p = 0.04), protein foods (p < 0.001), empty calories (p = 0.007) and total calories than females (p < 0.001). A diet characterized by greater intake of vegetables, fruits, protein foods, and dairy was associated with a Canadian undergraduate population meeting the greatest number of nutrient requirements.

  3. Usual nutrient intakes of U.S. infants and toddlers generally meet or exceed Dietary Reference Intakes: Findings from NHANES 2009-2012

    USDA-ARS?s Scientific Manuscript database

    To our knowledge, few studies have described the usual nutrient intakes of U.S. children aged <2 y or assessed the nutrient adequacy of their diets relative to the recommended Dietary Reference Intakes (DRIs). We estimated the usual nutrient intake of U.S. children aged 6-23 months examined in NHAN...

  4. Data from Controlled Metabolic Ward Studies Provide Guidance for the Determination of Status Indicators and Dietary Requirements for Magnesium.

    PubMed

    Nielsen, Forrest H; Johnson, Lu Ann K

    2017-05-01

    Determination of whether magnesium (Mg) is a nutrient of public health concern has been hindered by questionable Dietary Recommended Intakes (DRIs) and problematic status indicators that make Mg deficiency assessment formidable. Balance data obtained since 1997 indicate that the EAR and RDA for 70-kg healthy individuals are about 175 and 250 mg/day, respectively, and these DRIs decrease or increase based on body weight. These DRIs are less than those established for the USA and Canada. Urinary excretion data from tightly controlled metabolic unit balance studies indicate that urinary Mg excretion is 40 to 80 mg (1.65 to 3.29 mmol)/day when Mg intakes are <250 mg (10.28 mmol)/day, and 80 to 160 mg (3.29 to 6.58 mmol)/day when intakes are >250 mg (10.28 mmol)/day. However, changing from low to high urinary excretion with an increase in dietary intake occurs within a few days and vice versa. Thus, urinary Mg as a stand-alone status indicator would be most useful for population studies and not useful for individual status assessment. Tightly controlled metabolic unit depletion/repletion experiments indicate that serum Mg concentrations decrease only after a prolonged depletion if an individual has good Mg reserves. These experiments also found that, although individuals had serum Mg concentrations approaching 0.85 mmol/L (2.06 mg/dL), they had physiological changes that respond to Mg supplementation. Thus, metabolic unit findings suggest that individuals with serum Mg concentrations >0.75 mmol/L (1.82 mg/L), or as high as 0.85 mmol/L (2.06 mg/dL), could have a deficit in Mg such that they respond to Mg supplementation, especially if they have a dietary intake history showing <250 mg (10.28 mmol)/day and a urinary excretion of <80 mg (3.29 mmol)/day.

  5. Designing optimal food intake patterns to achieve nutritional goals for Japanese adults through the use of linear programming optimization models.

    PubMed

    Okubo, Hitomi; Sasaki, Satoshi; Murakami, Kentaro; Yokoyama, Tetsuji; Hirota, Naoko; Notsu, Akiko; Fukui, Mitsuru; Date, Chigusa

    2015-06-06

    Simultaneous dietary achievement of a full set of nutritional recommendations is difficult. Diet optimization model using linear programming is a useful mathematical means of translating nutrient-based recommendations into realistic nutritionally-optimal food combinations incorporating local and culture-specific foods. We used this approach to explore optimal food intake patterns that meet the nutrient recommendations of the Dietary Reference Intakes (DRIs) while incorporating typical Japanese food selections. As observed intake values, we used the food and nutrient intake data of 92 women aged 31-69 years and 82 men aged 32-69 years living in three regions of Japan. Dietary data were collected with semi-weighed dietary record on four non-consecutive days in each season of the year (16 days total). The linear programming models were constructed to minimize the differences between observed and optimized food intake patterns while also meeting the DRIs for a set of 28 nutrients, setting energy equal to estimated requirements, and not exceeding typical quantities of each food consumed by each age (30-49 or 50-69 years) and gender group. We successfully developed mathematically optimized food intake patterns that met the DRIs for all 28 nutrients studied in each sex and age group. Achieving nutritional goals required minor modifications of existing diets in older groups, particularly women, while major modifications were required to increase intake of fruit and vegetables in younger groups of both sexes. Across all sex and age groups, optimized food intake patterns demanded greatly increased intake of whole grains and reduced-fat dairy products in place of intake of refined grains and full-fat dairy products. Salt intake goals were the most difficult to achieve, requiring marked reduction of salt-containing seasoning (65-80%) in all sex and age groups. Using a linear programming model, we identified optimal food intake patterns providing practical food choices and meeting nutritional recommendations for Japanese populations. Dietary modifications from current eating habits required to fulfil nutritional goals differed by age: more marked increases in food volume were required in younger groups.

  6. Fractional Zinc Absorption for Men, Women, and Adolescents Is Overestimated in the Current Dietary Reference Intakes.

    PubMed

    Armah, Seth M

    2016-06-01

    The fractional zinc absorption values used in the current Dietary Reference Intakes (DRIs) for zinc were based on data from published studies. However, the inhibitory effect of phytate was underestimated because of the low phytate content of the diets in the studies used. The objective of this study was to estimate the fractional absorption of dietary zinc from the US diet by using 2 published algorithms. Nutrient intake data were obtained from the NHANES 2009-2010 and the corresponding Food Patterns Equivalents Database. Data were analyzed with the use of R software by taking into account the complex survey design. The International Zinc Nutrition Consultative Group (IZiNCG; Brown et al. Food Nutr Bull 2004;25:S99-203) and Miller et al. (Br J Nutr 2013;109:695-700) models were used to estimate zinc absorption. Geometric means (95% CIs) of zinc absorption for all subjects were 30.1% (29.9%, 30.2%) or 31.3% (30.9%, 31.6%) with the use of the IZiNCG model and Miller et al. model, respectively. For men, women, and adolescents, absorption values obtained in this study with the use of the 2 models were 27.2%, 31.4%, and 30.1%, respectively, for the IZiNCG model and 28.0%, 33.0%, and 31.6%, respectively, for the Miller et al. model, compared with the 41%, 48%, and 40%, respectively, used in the current DRIs. For preadolescents, estimated absorption values (31.1% and 32.8% for the IZiNCG model and Miller et al. model, respectively) compare well with the conservative estimate of 30% used in the DRIs. When the new estimates of zinc absorption were applied to the current DRI values for men and women, the results suggest that the Estimated Average Requirement (EAR) and RDA for these groups need to be increased by nearly one-half of the current values in order to meet their requirements for absorbed zinc. These data suggest that zinc absorption is overestimated for men, women, and adolescents in the current DRI. Upward adjustments of the DRI for these groups are recommended. © 2016 American Society for Nutrition.

  7. Micronutrient Gaps in Three Commercial Weight-Loss Diet Plans.

    PubMed

    G Engel, Matthew; J Kern, Hua; Brenna, J Thomas; H Mitmesser, Susan

    2018-01-20

    Weight-loss diets restrict intakes of energy and macronutrients but overlook micronutrient profiles. Commercial diet plans may provide insufficient micronutrients. We analyzed nutrient profiles of three plans and compared their micronutrient sufficiency to Dietary Reference Intakes (DRIs) for male U.S. adults. Hypocaloric vegan (Eat to Live-Vegan, Aggressive Weight Loss; ETL-VAWL), high-animal-protein low-carbohydrate (Fast Metabolism Diet; FMD) and weight maintenance (Eat, Drink and Be Healthy; EDH) diets were evaluated. Seven single-day menus were sampled per diet ( n = 21 menus, 7 menus/diet) and analyzed for 20 micronutrients with the online nutrient tracker CRON-O-Meter. Without adjustment for energy intake, the ETL-VAWL diet failed to provide 90% of recommended amounts for B 12 , B₃, D, E, calcium, selenium and zinc. The FMD diet was low (<90% DRI) in B₁, D, E, calcium, magnesium and potassium. The EDH diet met >90% DRIs for all but vitamin D, calcium and potassium. Several micronutrients remained inadequate after adjustment to 2000 kcal/day: vitamin B 12 in ETL-VAWL, calcium in FMD and EDH and vitamin D in all diets. Consistent with previous work, micronutrient deficits are prevalent in weight-loss diet plans. Special attention to micronutrient rich foods is required to reduce risk of micronutrient deficiency in design of commercial diets.

  8. Micronutrient Gaps in Three Commercial Weight-Loss Diet Plans

    PubMed Central

    J. Kern, Hua; Brenna, J. Thomas; H. Mitmesser, Susan

    2018-01-01

    Weight-loss diets restrict intakes of energy and macronutrients but overlook micronutrient profiles. Commercial diet plans may provide insufficient micronutrients. We analyzed nutrient profiles of three plans and compared their micronutrient sufficiency to Dietary Reference Intakes (DRIs) for male U.S. adults. Hypocaloric vegan (Eat to Live-Vegan, Aggressive Weight Loss; ETL-VAWL), high-animal-protein low-carbohydrate (Fast Metabolism Diet; FMD) and weight maintenance (Eat, Drink and Be Healthy; EDH) diets were evaluated. Seven single-day menus were sampled per diet (n = 21 menus, 7 menus/diet) and analyzed for 20 micronutrients with the online nutrient tracker CRON-O-Meter. Without adjustment for energy intake, the ETL-VAWL diet failed to provide 90% of recommended amounts for B12, B3, D, E, calcium, selenium and zinc. The FMD diet was low (<90% DRI) in B1, D, E, calcium, magnesium and potassium. The EDH diet met >90% DRIs for all but vitamin D, calcium and potassium. Several micronutrients remained inadequate after adjustment to 2000 kcal/day: vitamin B12 in ETL-VAWL, calcium in FMD and EDH and vitamin D in all diets. Consistent with previous work, micronutrient deficits are prevalent in weight-loss diet plans. Special attention to micronutrient rich foods is required to reduce risk of micronutrient deficiency in design of commercial diets. PMID:29361684

  9. Water and beverage consumption among children age 4-13y in the United States: analyses of 2005–2010 NHANES data

    PubMed Central

    2013-01-01

    Background Few studies have examined water consumption patterns among US children. Additionally, recent data on total water consumption as it relates to the Dietary Reference Intakes (DRI) are lacking. This study evaluated the consumption of plain water (tap and bottled) and other beverages among US children by age group, gender, income-to-poverty ratio, and race/ethnicity. Comparisons were made to DRI values for water consumption from all sources. Methods Data from two non-consecutive 24-hour recalls from 3 cycles of NHANES (2005–2006, 2007–2008 and 2009–2010) were used to assess water and beverage consumption among 4,766 children age 4-13y. Beverages were classified into 9 groups: water (tap and bottled), plain and flavored milk, 100% fruit juice, soda/soft drinks (regular and diet), fruit drinks, sports drinks, coffee, tea, and energy drinks. Total water intakes from plain water, beverages, and food were compared to DRIs for the US. Total water volume per 1,000 kcal was also examined. Results Water and other beverages contributed 70-75% of dietary water, with 25-30% provided by moisture in foods, depending on age. Plain water, tap and bottled, contributed 25-30% of total dietary water. In general, tap water represented 60% of drinking water volume whereas bottled water represented 40%. Non-Hispanic white children consumed the most tap water, whereas Mexican-American children consumed the most bottled water. Plain water consumption (bottled and tap) tended to be associated with higher incomes. No group of US children came close to satisfying the DRIs for water. At least 75% of children 4-8y, 87% of girls 9-13y, and 85% of boys 9-13y did not meet DRIs for total water intake. Water volume per 1,000 kcal, another criterion of adequate hydration, was 0.85-0.95 L/1,000 kcal, short of the desirable levels of 1.0-1.5 L/1,000 kcal. Conclusions Water intakes at below-recommended levels may be a cause for concern. Data on water and beverage intake for the population and by socio-demographic group provides useful information to target interventions for increasing water intake among children. PMID:23782914

  10. Water and beverage consumption among children age 4-13y in the United States: analyses of 2005-2010 NHANES data.

    PubMed

    Drewnowski, Adam; Rehm, Colin D; Constant, Florence

    2013-06-19

    Few studies have examined water consumption patterns among U.S. children. Additionally, recent data on total water consumption as it relates to the Dietary Reference Intakes (DRI) are lacking. This study evaluated the consumption of plain water (tap and bottled) and other beverages among US children by age group, gender, income-to-poverty ratio, and race/ethnicity. Comparisons were made to DRI values for water consumption from all sources. Data from two non-consecutive 24-hour recalls from 3 cycles of NHANES (2005-2006, 2007-2008 and 2009-2010) were used to assess water and beverage consumption among 4,766 children age 4-13y. Beverages were classified into 9 groups: water (tap and bottled), plain and flavored milk, 100% fruit juice, soda/soft drinks (regular and diet), fruit drinks, sports drinks, coffee, tea, and energy drinks. Total water intakes from plain water, beverages, and food were compared to DRIs for the U.S. Total water volume per 1,000 kcal was also examined. Water and other beverages contributed 70-75% of dietary water, with 25-30% provided by moisture in foods, depending on age. Plain water, tap and bottled, contributed 25-30% of total dietary water. In general, tap water represented 60% of drinking water volume whereas bottled water represented 40%. Non-Hispanic white children consumed the most tap water, whereas Mexican-American children consumed the most bottled water. Plain water consumption (bottled and tap) tended to be associated with higher incomes. No group of U.S. children came close to satisfying the DRIs for water. At least 75% of children 4-8y, 87% of girls 9-13y, and 85% of boys 9-13y did not meet DRIs for total water intake. Water volume per 1,000 kcal, another criterion of adequate hydration, was 0.85-0.95 L/1,000 kcal, short of the desirable levels of 1.0-1.5 L/1,000 kcal. Water intakes at below-recommended levels may be a cause for concern. Data on water and beverage intake for the population and by socio-demographic group provides useful information to target interventions for increasing water intake among children.

  11. The evolving landscape of RAAS inhibition: from ACE inhibitors to ARBs, to DRIs and beyond.

    PubMed

    Epstein, Benjamin J; Leonard, Paul T; Shah, Niren K

    2012-06-01

    Chronic renin-angiotensin-aldosterone system (RAAS) activation has far-reaching effects on cardiometabolic risk and is a substantial contributor to cardiovascular (CV) disease and renal dysfunction. The vascular effects of sustained RAAS activation are associated with hemodynamic imbalances, as well as inflammatory stimulation and prothrombotic processes that lead to fibrosis, endothelial dysfunction and cellular remodeling. RAAS inhibition therapies, which include the use of angiotensin-converting enzyme inhibitors, angiotensin receptor blockers and more recently, direct renin inhibitors, have been used in clinical practice for more than 30 years. Our understanding of how these drugs work, alone and in combination, has contributed to an expanding landscape of treatment options and established RAAS inhibition as essential for reducing the risk of CV and renal disease. This perspective provides a historical overview of how RAAS inhibitors have evolved to their present-day status and will discuss recently discovered functions for components of this complicated and powerful regulatory system.

  12. Nutrient Intake and Depression Symptoms in Spanish Children: The ANIVA Study

    PubMed Central

    Rubio-López, Nuria; Morales-Suárez-Varela, María; Pico, Yolanda; Livianos-Aldana, Lorenzo; Llopis-González, Agustín

    2016-01-01

    The aim of this study was to examine the relationship between nutritional intake and depressive symptoms in Valencian schoolchildren. The ANIVA (Antropometria y Nutricion Infantil de Valencia) study is a descriptive cross-sectional study. During academic year 2013–2014, 710 schoolchildren aged 6–9 years were selected from eleven primary schools in Valencia (Spain). Children’s dietary intake was measured on three-day food records, completed by parents/guardians; children completed the 20-item Center for Epidemiologic Studies Depression Scale for Children (CES-DC) Questionnaire to measure depressive symptoms. Weight, height, and body mass index (BMI), and z-scores were evaluated in all subjects. Nutrient adequacy was assessed using Spanish dietary recommended intakes (DRIs); 20.70% of the sample presented depressive symptoms. We identified a positive association between children with depressive symptoms and non-depressive symptoms for thiamin, vitamin K, and bromine (p < 0.05), and a negative association for protein, carbohydrates, pantothenic acid, biotin, vitamin B12 and E, zinc, manganese, cobalt, and aluminum (p < 0.05). Statistically significant differences were found between both groups according to the DRIs for intakes of total energy (p = 0.026), fiber (p < 0.001), vitamin C (p < 0.001), vitamin E (p = 0.004), magnesium (p = 0.018), and iron (p = 0.013). Our results demonstrated that carbohydrates were the most closely associated factor with depressive symptoms, and highlight the potential significant public health implications of inadequate nutritional intake on schoolchildren’s mental health. PMID:27011198

  13. Nutrient Intake and Depression Symptoms in Spanish Children: The ANIVA Study.

    PubMed

    Rubio-López, Nuria; Morales-Suárez-Varela, María; Pico, Yolanda; Livianos-Aldana, Lorenzo; Llopis-González, Agustín

    2016-03-22

    The aim of this study was to examine the relationship between nutritional intake and depressive symptoms in Valencian schoolchildren. The ANIVA (Antropometria y Nutricion Infantil de Valencia) study is a descriptive cross-sectional study. During academic year 2013-2014, 710 schoolchildren aged 6-9 years were selected from eleven primary schools in Valencia (Spain). Children's dietary intake was measured on three-day food records, completed by parents/guardians; children completed the 20-item Center for Epidemiologic Studies Depression Scale for Children (CES-DC) Questionnaire to measure depressive symptoms. Weight, height, and body mass index (BMI), and z-scores were evaluated in all subjects. Nutrient adequacy was assessed using Spanish dietary recommended intakes (DRIs); 20.70% of the sample presented depressive symptoms. We identified a positive association between children with depressive symptoms and non-depressive symptoms for thiamin, vitamin K, and bromine (p < 0.05), and a negative association for protein, carbohydrates, pantothenic acid, biotin, vitamin B12 and E, zinc, manganese, cobalt, and aluminum (p < 0.05). Statistically significant differences were found between both groups according to the DRIs for intakes of total energy (p = 0.026), fiber (p < 0.001), vitamin C (p < 0.001), vitamin E (p = 0.004), magnesium (p = 0.018), and iron (p = 0.013). Our results demonstrated that carbohydrates were the most closely associated factor with depressive symptoms, and highlight the potential significant public health implications of inadequate nutritional intake on schoolchildren's mental health.

  14. Older Adults Need Guidance to Meet Nutritional Recommendations

    PubMed Central

    Foote, Janet A.; Giuliano, Anna R.; Harris, Robin B.

    2009-01-01

    Objective The purpose of this study was to compare the diet of healthy, free-living senior volunteers to the dietary reference intakes (DRIs) and Food Guide Pyramid recommendations. Methods This study was a cross-sectional assessment of dietary habits, as measured using a standardized food frequency questionnaire, among 1740 healthy Southwestern U.S. adults, aged 51 to 85 years. Assessment of independently-living volunteers to chemoprevention trials provides an efficient mechanism to profile typical dietary habits among the older adult population. Results Daily estimated macronutrient intakes exceeded recommended proportions of protein and fat. In contrast, more than 60% of this senior population reported dietary vitamin D, vitamin E, folate and calcium intakes below estimated average requirements (EAR). Based on the Food Guide Pyramid recommendations, fewer than 10% of the older adults consumed the recommended daily dairy and grain servings. More females than males consumed recommended vegetable (49% versus 40%) and fruit (53% versus 48%) servings (p <, 0.05). More males consumed recommended grain (11% versus 7%) and protein (78% versus 73%) servings (p <, 0.05) than females. Conclusions Mean micronutrient intakes compared well with DRIs, although fewer than one-half of these older adults consumed recommended levels for vitamin D, vitamin E, folate, and calcium or daily food servings of dairy, grains, vegetables or fruits. Since the beneficial aspects of foods are not limited to essential nutrients, nutrition recommendations to older adults may be improved by emphasizing daily servings of nutrient-dense choices within the Food Pyramid. PMID:11022877

  15. Micronutrient Intake among Children in Puerto Rico: Dietary and Multivitamin-Multimineral Supplement Sources.

    PubMed

    Lopez-Cepero, Andrea; Torres, Roxana; Elias, Augusto; Rosal, Milagros C; Palacios, Cristina

    2015-12-01

    Micronutrients are critical for healthy growth and development of children. Micronutrient intake from dietary sources is inadequate among some children and may be improved by use of multivitamin and multimineral (MVMM) supplements. To assess micronutrient intake from dietary and MVMM supplement sources among 12-year-old children in Puerto Rico. A representative sample of 732 children enrolled in an oral health study in Puerto Rico, who completed dietary and MVMM assessments through one 24-h recall, were included in this analysis. Micronutrient intake sources were described and compared to the Dietary Reference Intakes (DRIs) using the Estimated Average Requirement when available (used Adequate Intake for vitamin K and pantothenic acid). Micronutrient profiles of MVMM users and non-users were compared using t-tests. Mean intakes of vitamins A, D, E, and K, pantothenic acid, calcium, and magnesium from food and beverage sources were below the DRIs. From food and beverage sources, MVMM users had higher intakes of riboflavin and folate compared to non-users (p < 0.05). When MVMM supplements were taken into account, users had higher intakes of all nutrients except vitamin K. With the help of MVMM, users increased intake of vitamins E, A, D, and pantothenic acid to IOM-recommended levels but calcium, magnesium, and vitamin K remained below guidelines. Micronutrient intake from diet was below the IOM-recommended levels in the total sample. MVMM use improved intake of selected micronutrients and facilitated meeting recommendations for some nutrients. Public health measures to improve micronutrient intake among children in Puerto Rico are needed.

  16. Application of quality by design concept to develop a dual gradient elution stability-indicating method for cloxacillin forced degradation studies using combined mixture-process variable models.

    PubMed

    Zhang, Xia; Hu, Changqin

    2017-09-08

    Penicillins are typical of complex ionic samples which likely contain large number of degradation-related impurities (DRIs) with different polarities and charge properties. It is often a challenge to develop selective and robust high performance liquid chromatography (HPLC) methods for the efficient separation of all DRIs. In this study, an analytical quality by design (AQbD) approach was proposed for stability-indicating method development of cloxacillin. The structures, retention and UV characteristics rules of penicillins and their impurities were summarized and served as useful prior knowledge. Through quality risk assessment and screen design, 3 critical process parameters (CPPs) were defined, including 2 mixture variables (MVs) and 1 process variable (PV). A combined mixture-process variable (MPV) design was conducted to evaluate the 3 CPPs simultaneously and a response surface methodology (RSM) was used to achieve the optimal experiment parameters. A dual gradient elution was performed to change buffer pH, mobile-phase type and strength simultaneously. The design spaces (DSs) was evaluated using Monte Carlo simulation to give their possibility of meeting the specifications of CQAs. A Plackett-Burman design was performed to test the robustness around the working points and to decide the normal operating ranges (NORs). Finally, validation was performed following International Conference on Harmonisation (ICH) guidelines. To our knowledge, this is the first study of using MPV design and dual gradient elution to develop HPLC methods and improve separations for complex ionic samples. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. Food, plant food, and vegetarian diets in the US dietary guidelines: conclusions of an expert panel.

    PubMed

    Jacobs, David R; Haddad, Ella H; Lanou, Amy Joy; Messina, Mark J

    2009-05-01

    We summarize conclusions drawn from a panel discussion at the "Fifth International Congress on Vegetarian Nutrition" about the roles of and emphasis on food, plant food, and vegetarianism in current and future US dietary guidelines. The most general recommendation of the panel was that future dietary guidelines, following the lead of the 2005 Dietary Guidelines Advisory Committee, should emphasize food-based recommendations and thinking to the full extent that evidence allows. Although nutrient-based thinking and Dietary Reference Intakes (DRIs) may help ensure an adequate diet in the sense that deficiency states are avoided, the emphasis on DRIs may not capture many important nutritional issues and may inhibit a focus on foods. More generally, in the context of the conference on vegetarian nutrition, this report focuses on the history and structure of the Dietary Guidelines Advisory Committee, on various plant food-oriented recommendations that are supported by literature evidence, and on mechanisms for participating in the process of forming dietary guidelines. Among recommendations that likely would improve health and the environment, some are oriented toward increased plant food consumption and some toward vegetarianism. The literature on health effects of individual foods and whole lifestyle diets is insufficient and justifies a call for future food-oriented research, including expanding the evidence base for plant-based and vegetarian diets. The Dietary Guidelines Advisory Committee's role should be carried forward to creation of a publicly accessible icon (eg, the current pyramid) and related materials to ensure that the science base is fully translated for the public.

  18. Soil solution and sugar maple response to NH(4)NO (3) additions in a base-poor northern hardwood forest of Québec, Canada.

    PubMed

    Moore, Jean-David; Houle, Daniel

    2009-08-01

    Nitrogen additions (NH4NO3) at rates of three- and ten-fold ambient atmospheric deposition (8.5 kg ha(-1) year(-1)) were realised in an acid- and base-poor northern hardwood forest of Québec, Canada. Soil solution chemistry, foliar chemistry, crown dieback and basal area growth of sugar maple (Acer saccharum Marsh.) were measured. Except for a transitory increase of NO3 and NH4 concentrations, there was no persistent increase in their level in soil solution 3 years after N treatments, with the exception of one plot out of three, that received the highest N addition, beginning to show persistent and high NO3 concentrations after 2 years of N additions. Three years of N additions have significantly increased the N DRIS index of sugar maple but not N foliar concentration. Potassium, Ca and Mn foliar concentrations, as well as P and Ca DRIS indices, decreased in treated plots after 3 years. No treatment effect was observed for basal area growth and dieback rate. One unexpected result was the significant decrease in foliar Ca even in the treated plots that received low N rates, despite the absence of significant NO3-induced leaching of Ca. The mechanism responsible for the decrease in foliar Ca is not known. Our results, however, clearly demonstrate that increased N deposition at sites with low base saturation may affect Ca nutrition even when clear signs of N saturation are not observed.

  19. Current status of renin-aldosterone angiotensin system-targeting anti-hypertensive drugs as therapeutic options for Alzheimer's disease.

    PubMed

    Ashby, Emma Louise; Kehoe, Patrick G

    2013-10-01

    Hypertension is a modifiable risk factor for Alzheimer's disease (AD) and other dementias. Yet, despite this well-documented association, few of the current strategies to treat AD are directed at this possible target. The renin-aldosterone angiotensin system (RAAS) is a centrally active modifiable pathway that is involved in cerebral blood flow regulation. Currently, three classes of RAAS-targeting drugs are licensed for treatment of peripheral hypertension--angiotensin-converting enzyme inhibitors (ACE-Is), angiotensin II receptor blockers (ARBs) and direct renin inhibitors (DRIs). All of these are generally well tolerated and have been shown to offer varying degrees of protection on aspects of cognition and dementia, thus making them an attractive therapeutic option for AD. This review summarises existing evidence regarding the plausibility of using RAAS-targeting drugs as a strategy to treat AD and highlights unresolved aspects to such approaches, namely the potential impact of altering angiotensin II-mediated processes in the central nervous system. Continued biochemical research of the RAAS pathway in combination with formal investigation of current RAAS-modifying drugs in randomised clinical trials is now necessary to determine their therapeutic value in AD.

  20. High-resolution Body Wave Tomography of the Ross Sea Embayment, Antarctica

    NASA Astrophysics Data System (ADS)

    Nyblade, A.; White-Gaynor, A.; Wiens, D.; Aster, R. C.; Gerstoft, P.; Bromirski, P. D.; Stephen, R. A.; Winberry, J. P.; Huerta, A. D.; Anandakrishnan, S.; Wilson, T. J.

    2016-12-01

    The West Antarctic Rift System (WARS) remains the least understood continental rift system on the planet. The WARS is largely composed of the Ross Sea Embayment, which is overlain by the Ross Ice Shelf between Marie Byrd Land and the Transantarctic Mountains. Active volcanism on Ross Island continues to challenge our understanding of the seismically quiescent rift system. Previous regional-scale body wave tomographic investigations have identified areas of low seismic wave speed to about 200 km depth beneath Ross Island. However mantle structure under the Ross Sea Embayment away from Ross Island has not been previously well imaged. For this investigation we utilize teleseismic P waves recorded on the recently deployed RIS/DRIS network, which consists of 34 seismometers deployed across the Ross Ice Shelf, along with data from nearby POLENET stations and TAMSEIS stations. Relative P wave travel time residuals were obtained from 560 events using a multichannel cross correlation method, and have been inverted to obtain a preliminary model of the upper mantle. Initial results suggest that the low wave speed structure under Ross Island does not extend beneath the Ross Sea Embayment portion of the WARS.

  1. ASSESSMENT OF THE FOOD PATTERNS OF IMMIGRANT ECUADORIAN POPULATION IN SOUTHERN SPAIN BASED ON A 24-H FOOD RECALL SURVEY.

    PubMed

    Neira-Mosquera, Juan Alejandro; Sanchez-Llaguno, Sungey; Pérez-Rodríguez, Fernando; Moreno-Rojas, Rafael

    2015-08-01

    Ecuador is a country with limited nutritional information, with exception of some general studies supported by Food Agriculture Organization (FAO) Aims: to carry out a nutritional assessment of the diet of Ecuadorian immigrant population in Southern Spain to determine differences in food patterns and possible nutritional deficiencies. the nutritional assessment was based on a 24-h food recall survey applied to the Ecuadorian population residing in Seville and Córdoba (Spain) in combination with the application of national and international food composition data bases. Nutrient intake levels and fulfillment of Dietary Reference Intakes (DRIs) were estimated and statistically tested for social, sex, age and geographical factors. macronutrient distributions and nutrient intake levels in relation with DRIs were adequate in most cases. Importantly, Ecuadorian food habits were still present in immigrant population, with rice being the main energy source. Intakes levels were significantly different for several nutrients depending on age group, sex, place of residence and professional occupation. Comparison with previous nutritional data from Ecuador revealed a better nutritional status of immigrant population in Spain, though deficiencies in fiber, vitamin E, I and Se were detected in the diet of both populations. Nevertheless, data for these deficiencies were insufficient to be conclusive given both limitations in the food composition data bases (e.g. Se) and the lack of more adequate information tools for its assessment (e.g. long-term studies for vitamin E). the results in the present study evidenced that Ecuadorian immigrants in Spain showed more adequate food patterns that those reported for Ecuador. These data can be helpful to get further insight into the nutritional value of Ecuadorian diet and develop suitable nutrition intervention. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

  2. Protein dietary reference intakes may be inadequate for vegetarians if low amounts of animal protein are consumed.

    PubMed

    Kniskern, Megan A; Johnston, Carol S

    2011-06-01

    The health benefits of vegetarian diets are well-recognized; however, long-term adherence to these diets may be associated with nutrient inadequacies, particularly vitamins B12 and D, calcium, iron, zinc, and protein. The dietary reference intakes (DRIs) expert panels recommended adjustments to the iron, zinc, and calcium DRIs for vegetarians to account for decreased bioavailability, but no adjustments were considered necessary for the protein DRI under the assumption that vegetarians consume about 50% of protein from animal (dairy/egg) sources. This study examined dietary protein sources in a convenience sample of 21 young adult vegetarian women who completed food logs on 4 consecutive days (3 weekdays and 1 weekend day). The daily contribution percentages of protein consumed from cereals, legumes, nuts/seeds, fruits/vegetables, and dairy/egg were computed, and the protein digestibility corrected amino acid score of the daily diets was calculated. The calculated total dietary protein digestibility score for participants was 82 ± 1%, which differed significantly (P < 0.001) from the DRI reference score, 88%, and the 4-d average protein digestibility corrected amino acid score for the sample was 80 ± 2%, which also differed significantly (P < 0.001) from the DRI reference value, 100%. The analyses indicated that animal protein accounted for only 21% of dietary protein. This research suggests that the protein DRI for vegetarians consuming less than the expected amounts of animal protein (45% to 50% of total protein) may need to be adjusted from 0.8 to about 1.0 g/kg to account for decreased protein bioavailability. Copyright © 2011 Elsevier Inc. All rights reserved.

  3. [Intergenerational differences on the nutritional status and lifestyle of Chinese residents].

    PubMed

    Su, Chang; Wang, Huijun; Zhang, Jiguo; Du, Wenwen; Wang, Zhihong; Zhang, Ji; Zhai, Fengying; Zhang, Bing

    2012-05-01

    To study the diversities on nutritional status and lifestyle of adult Chinese residents born in different years. The data of healthy adult residents born in the 1960s and 1980s were selected from the CHNS 1993 and 2009. Information on physical examination, nutrient intake and lifestyle factors were used as indicators to evaluate the nutritional status of residents; data was analyzed by SAS and STATA software. (1) Weight, height, BMI, waist circumference, hip circumference, waist-hip ratio, skin fold thickness, overweight/obesity, hypertension rate of residents born in the 1980s were all significantly higher than residents born in the 1960s. (2) Dietary fats intake, percentage of energy contributed from total fat, cholesterol intake, calcium intake and the rate of energy and cholesterol intake exceeding the Chinese dietary reference intakes (Chinese DRIs) of residents born in the 1980s were all significantly higher than residents born in the 1960s, however, the energy intake,carbohydrate intake, salt intake, vitamin B1 intake, vitamin C intake, the energy contributed from carbohydrates and the rate of vitamin B1 intake and vitamin C intake exceeding the Chinese DRIs of residents born in the 1980s were all significantly lower in residents born in the 1960s. (3) The smoking rates, rates of drinking tea and the percentage of population engaged in medium or vigorous physical activity of residents born in the 1980s were all significantly lower than residents born in the 1960s. The diversity of nutritional status and lifestyle in different generations could not be ignored, and the phenomenon of increased prevalence of nutrition-related non-communicable diseases (NR-NCDs) of residents born in 1980s should be concerned.

  4. Eating behaviors, nutritional status, and menstrual function in elite female adolescent volleyball players.

    PubMed

    Beals, Katherine A

    2002-09-01

    Nutritional status, eating behaviors and menstrual function was examined in 23 nationally ranked female adolescent volleyball players using a health/weight/ dieting/menstrual history questionnaire, the Eating Disorder Inventory (EDI), and the Body Shape Questionnaire (BSQ). Nutrient and energy intakes (El) and energy expenditure (EE) were determined by 3-d weighed food records and activity logs. Iron (Fe), vitamins C, B12, and Folate status were assessed using serum and whole blood. Mean El (2248 +/- 414 kcal/d) was less than EE (2815 +/- 306 kcal/d). Mean carbohydrate (5.4 +/-1.0g/kg/d) and protein (1.1+/-0.3g/kg/d) intakes were below recommended levels for highly active women. Mean intakes for folate, Fe, Ca, Mg, and Zn were less than the respective RDAs/DRIs and almost 50% of the athletes were consuming less than the RDAs/DRIs for the B-complex vitamins and vitamin C. Three athletes presented with Fe deficiency anemia (Hb <12 mg/dL), while marginal vitamin B12 status (<200 pg/ml) and vitamin C status (<28 mmol/L) were found in 1 and 4 athletes, respectively. Approximately 1/2 of the athletes reported actively "dieting". Mean BSQ and EDI subscales scores were within the normal ranges; yet, elevated scores on these scales were reported by 26% and 35% of athletes, respectively. Past or present amenorrhea was reported by 17% of the athletes and 13% and 48%, reported past or present oligomenorrhea and "irregular" menstrual cycles, respectively. These results indicate that elite adolescent volleyball players are at risk for menstrual dysfunction and have energy and nutrient intakes that place them at risk for nutritional deficiencies and compromised performance.

  5. Optimal formulations of local foods to achieve nutritional adequacy for 6–23-month-old rural Tanzanian children

    PubMed Central

    Raymond, Jofrey; Kassim, Neema; Rose, Jerman W.; Agaba, Morris

    2017-01-01

    ABSTRACT Background: Achieving nutritional goals of infants and young children while maintaining the intake of local and culture-specific foods can be a daunting task. Diet optimisation using linear goal programming (LP) can effectively generate optimal formulations incorporating local and culturally acceptable foods. Objective: The primary objective of this study was to determine whether a realistic and affordable diet that achieves dietary recommended intakes (DRIs) for 22 selected nutrients can be formulated for rural 6–23-month-old children in Tanzania. Design: Dietary intakes of 400 children aged 6–23 months were assessed using a weighed dietary record (WDR), 24-hour dietary recalls and a 7-days food record. A market survey was also carried out to estimate the cost per 100 g of edible portion of foods that are commonly consumed in the study area. Dietary and market survey data were then used to define LP model parameters for diet optimisation. All LP analyses were done using linear program solver (LiPS) version 1.9.4 to generate optimal food formulations. Results: Optimal formulations that achieved DRIs for 20 nutrients for children aged 6–11 months and all selected nutrients for children aged 12–23 months were successfully developed at a twofold cost of the observed food purchase across age groups. Optimal formulations contained a mixture of ingredients such as wholegrain cereals, Irish potatoes, pulses and seeds, fish and poultry meat as well as fruits and vegetables that can be sourced locally. Conclusions: Our findings revealed that given the available food choices, it is possible to develop optimal formulations that can improve dietary adequacy for rural 6–23-month-old children if food budget for the child’s diets is doubled. These findings suggest the need for setting alternative interventions which can help households increase access to nutrient-dense foods that can fill the identified nutrient gaps. PMID:28814951

  6. Effective translation of current dietary guidance: understanding and communicating the concepts of minimal and optimal levels of dietary protein.

    PubMed

    Rodriguez, Nancy R; Miller, Sharon L

    2015-04-29

    Dietitians and health care providers have critical roles in the translation of the dietary guidance to practice. The protein content of diets for adults can be based on the Recommended Dietary Allowance (RDA) of 0.80 g/kg per day. Alternatively, the most recent Dietary Reference Intakes (DRIs) for macronutrients reflect expanded guidance for assessing protein needs and consider the relative relation of absolute amounts of protein, carbohydrate, and fat to total energy intake in the context of chronic disease prevention. The Acceptable Macronutrient Distribution Range (AMDR) reflects the interrelation between the macronutrients and affords dietitians and clinicians additional flexibility in diet planning. Accounting for the caloric value of RDAs for carbohydrate and fat, "flexible calories" emerge as an opportunity to create varied eating plans that provide for protein intakes in excess of the RDA but within the AMDR. Protein Summit 2.0 highlighted the growing body of scientific evidence documenting the benefits of higher protein intakes at amounts approximating twice the RDA, which include promotion of healthy body weight and preservation of lean body mass and functional ability with age. The essential amino acid (EAA) density of a food also emerged as a novel concept analogous to "nutrient density," which can enable the practitioner to calculate the caloric cost associated with a specific protein source to attain the daily requirement of EAAs to accomplish various health outcomes because these indispensable nutrients have a significant role in protein utilization and metabolic regulation. Tailoring recommendations unique to an individual's varying goals and needs remains a challenge. However, flexibility within the application of DRIs to include consideration of the AMDR provides a sound framework to guide practitioners in effective translation of current dietary guidance with a specific regard for the documented benefits of higher protein intakes. © 2015 American Society for Nutrition.

  7. Drug discovery in renin-angiotensin system intervention: past and future.

    PubMed

    Williams, Bryan

    2016-06-01

    The renin-angiotensin system (RAS) plays a central role in the control of blood pressure in the body and the way this interacts with other systems is widely recognized. This has not always been the case and this review summarizes how our knowledge has evolved from the initial discovery of renin by Tigerstedt and Berman in 1898. This includes the identification of angiotensin in the 1950s to the proposed relationship between this system, hypertension and ultimately cardiovascular disease. While the RAS is far more complex than originally thought, much is now known about this system and the wide ranging effects of angiotensin in the body. This has enabled the development of therapies that target the various proteins in this pathway and hence are implicated in disease. The first of these treatments was the angiotensin converting enzyme inhibitors (ACE-Is), followed by the angiotensin receptor blockers (ARBs), and more recently the direct renin inhibitors (DRIs). Clinical outcome trials have shown these drugs to be effective, but as they act at contrasting points in the RAS, there are differences in their efficacy and safety profiles. RAS blockade is the foundation of modern combination therapy with a calcium channel blocker and/or a diuretic given to reduce blood pressure and limit the impact of RAS activation. Other options that complement these treatments may be available in the future and will offer more choice to clinicians. © The Author(s), 2016.

  8. Macroelemental composition of cadmium stressed lettuce plants grown under conditions of intensive sulphur nutrition.

    PubMed

    Matraszek, Renata; Hawrylak-Nowak, Barbara; Chwil, Stanisław; Chwil, Mirosława

    2016-09-15

    Lettuce (Lactuca sativa L.) is moderately sensitive to cadmium (Cd) and shows high accumulation of this metal. Thus, this species is considered to be a good model for both identifying determinants controlling Cd accumulation in plant tissues and for developing breeding strategies aimed at limiting the accumulation of this metal in edible tissues. Simultaneously, lettuce is characterised by medium requirements for sulphur (S) - a macronutrient whose role is associated not only with proper growth and development, but also with stress tolerance. The common use of NPK fertilizers without sulphates (S-SO4) together with the progressive process of reducing emissions of S compounds to the natural environment may lead to deficiency of this element in plants. The present study evaluated the changes in macronutrient content and accumulation in Cd-stressed lettuce 'Justyna' supplied with different S doses. Four concentrations of Cd (0, 0.0002, 0.02 or 0.04 mM) and three levels of S applied in the form of S-SO4 (2, 6 or 9 mM S) were used. Cd exposure impaired the macronutrient balance and accumulation in lettuce. Intensive S nutrition to some extent alleviated Cd-induced toxicity. High S doses, especially 6 mM S, partially improved macronutrient status and restored the macronutrient balance. In Cd-stressed plants supplemented with additional S, an increase in root and shoot biomass and in the content of N, K and Mg was found, without significant changes in the Ca content. Simultaneously, the P and S contents in the biomass of both above- and underground organs remained unchanged. In the leaves, as opposite to the roots, intensive S nutrition reduced the accumulation of Cd. However, the foliar Cd concentration still exceeded the acceptable limits established for consumption. All the obtained results concerning the content of macronutrients and their ratios were referred, inter alia, to the standards i.e. the Diagnosis and Recommendation Integrated System (DRIS) norms. Copyright © 2016. Published by Elsevier Ltd.

  9. High-Resolution Body Wave Tomography of the Ross Sea Embayment, Antarctica

    NASA Astrophysics Data System (ADS)

    White-Gaynor, A.; Nyblade, A.; Wiens, D. A.; Aster, R. C.; Gerstoft, P.; Bromirski, P. D.; Stephen, R. A.

    2017-12-01

    The West Antarctic Rift System (WARS) is one of the least understood continental rift system on the planet. The 1000 km wide WARS includes the Ross Sea Embayment between Marie Byrd Land and the Transantarctic Mountains (TAMS). Active volcanism on Ross Island continues to challenge our understanding of the generally quiescent rift system. Previous regional-scale body wave tomographic investigations have identified areas of low seismic wave speeds to 200 km depth beneath Ross Island. However, the spatial extent of the low velocity structure across the entirety of the WARS remains poorly constrained due to the insufficient resolution of upper mantle structure under the Ross Sea Embayment away from Ross Island. We utilize teleseismic P wave observations recorded on the RIS/DRIS network, which consists of 34 seismometers deployed across the Ross Ice Shelf, along with data from nearby POLENET and TAMSEIS stations to better resolve this region. Relative P wave travel time residuals from 1300 teleseismic events, obtained using a multichannel cross-correlation method, have been inverted for a seismic velocity model of the upper mantle throughout the Ross Sea Embayment. Our results suggest that the low wave speed structure under Ross Island extends roughly halfway across the Embayment and south along the Transantarctic Mountains. This observation is consistent with a two-phase rifting history for the WARS in which broad, late Cretaceous rifting between Marie Byrd Land and the TAMS transitioned to more focused rifting along the TAMS margin in the Cenozoic.

  10. The neurohormonal network in the RAAS can bend before breaking.

    PubMed

    Wagman, Gabriel; Fudim, Marat; Kosmas, Constantine E; Panni, Robert E; Vittorio, Timothy J

    2012-06-01

    The renin-angiotensin-aldosterone system (RAAS) has evolved in humans as one of the main physiological networks by which blood pressure and blood flow to vital organs is maintained. The RAAS has evolved to circumvent life-threatening events such as hemorrhage and starvation. Although short-term activation of this system had been well suited to counteract such catastrophes of early man, excessive chronic activation of the RAAS plays a fundamental role in the development and progression of cardiovascular disease in modern man. The RAAS is an intricate network comprising a number of major organ systems (heart, kidney, and vasculature) and signaling pathways. The main protagonists are renin, angiotensinogen (Ang), angiotensin I (Ang I), angiotensin II (Ang II), and aldosterone (Aldo). The study and delineation of each of these substances has allowed modern medicine to create targets by which cardiovascular disease can be treated. The main modulators that have been synthesized in this respect are angiotensin-converting enzyme inhibitors (ACEIs), angiotensin receptor blockers (ARBs), mineralocorticoid receptor blockers (MRBs), and direct renin inhibitors (DRIs). Over the past few decades, each of these substances has proven efficacious to varying degrees amongst a number of clinical settings. Additionally, there exists data for and against the use of these agents in combination. The use of these agents in combination poses a larger question conceptually: can excessive pharmacological inhibition of the RAAS lead to patient harm? This perspective will examine the concept of a neurohormonal inhibition ceiling in pertinent experimental and clinical trials.

  11. Healthy diets with reduced environmental impact? - The greenhouse gas emissions of various diets adhering to the Dutch food based dietary guidelines.

    PubMed

    van de Kamp, Mirjam E; van Dooren, Corné; Hollander, Anne; Geurts, Marjolein; Brink, Elizabeth J; van Rossum, Caroline; Biesbroek, Sander; de Valk, Elias; Toxopeus, Ido B; Temme, Elisabeth H M

    2018-02-01

    To determine the differences in environmental impact and nutrient content of the current Dutch diet and four healthy diets aimed at lowering greenhouse gas (GHG) emissions. GHG emissions (as proxy for environmental impact) and nutrient content of the current Dutch diet and four diets adhering to the Dutch food based dietary guidelines (Wheel of Five), were compared in a scenario study. Scenarios included a healthy diet with or without meat, and the same diets in which only foods with relatively low GHG emissions are chosen. For the current diet, data from the Dutch National Food Consumption Survey 2007-2010 were used. GHG emissions (in kg CO 2 -equivalents) were based on life cycle assessments. Results are reported for men and women aged 19-30years and 31-50years. The effect on GHG emissions of changing the current Dutch diet to a diet according to the Wheel of Five (corresponding with the current diet as close as possible), ranged from -13% for men aged 31-50years to +5% for women aged 19-30years. Replacing meat in this diet and/or consuming only foods with relatively low GHG emissions resulted in average GHG emission reductions varying from 28-46%. In the scenarios in which only foods with relatively low GHG emissions are consumed, fewer dietary reference intakes (DRIs) were met than in the other healthy diet scenarios. However, in all healthy diet scenarios the number of DRIs being met was equal to or higher than that in the current diet. Diets adhering to food based dietary guidelines did not substantially reduce GHG emissions compared to the current Dutch diet, when these diets stayed as close to the current diet as possible. Omitting meat from these healthy diets or consuming only foods with relatively low associated GHG emissions both resulted in GHG emission reductions of around a third. These findings may be used to expand food based dietary guidelines with information on how to reduce the environmental impact of healthy diets. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  12. Dissecting the doctor-dancer relationship: health care decision making among American collegiate dancers.

    PubMed

    Air, Mary E; Grierson, Matthew J; Davenport, Kathleen L; Krabak, Brian J

    2014-03-01

    To examine perceptual influences on dancers' health care-seeking decisions and whether dancers' beliefs correlate with actual use of provider services when they are injured. Secondary aims were to understand how dancers may select physicians and what they consider to be the most important features of the medical consultation. Prospective cohort study. University and conservatory dance departments. Forty American collegiate dancers. Before the start of the dance semester, all participants completed a retrospective survey that included baseline demographic data, dance experience, a dance-related injury (DRI) inventory, previous health care exposures, and perceptions regarding health care treatment providers. Data regarding new DRIs and health care exposures were then prospectively collected every 2 weeks for 6 months. A DRI was defined as any neuromusculoskeletal condition sustained as the result of dancing activity that caused a dancer to stop or modify his or her dancing for more than 3 consecutive days. Dancers perceived dance teachers to be first-line treatment providers (47.5%), followed by physical therapists (PTs; 30%). Physicians were ranked third (12.5%) and only marginally higher than a dance colleague (10%). The dancers expressed a strong preference for nonsurgical rather than surgical physicians (87.5% versus 5.0%), and among physicians, the majority of dancers preferred subspecialists (60%), namely nonsurgical sports medicine doctors and physiatrists. During the 6-month prospective data-collection period, 25 dancers (69.4%) sustained 55 unique injuries, with 22 dancers (88%) and 34 injuries (61.8%) undergoing evaluation. Only 17.7% of injuries were evaluated by a physician. Dancers showed greater incongruity between their preinjury perceptions and postinjury use of physicians than they did with PTs (P = .0002). Although dancers did not perceive physicians to be first-line treatment providers for DRIs, these perceptions about physicians were poorly correlated with use. Instead, injured dancers' health care-seeking behaviors were more likely related to relatively decreased barriers to other nonphysician providers, as well as pre-existing referral pathways to PTs. Copyright © 2014 American Academy of Physical Medicine and Rehabilitation. Published by Elsevier Inc. All rights reserved.

  13. [Evaluation of dietary pattern and nutritional status of residents in southeast coastal area].

    PubMed

    Lü, Na; Shen, Minghao; Huang, Yixiang; Lu, Lijuan; Zheng, Shangpin; Chen, Kai

    2012-05-01

    To evaluate the dietary pattern and nutritional status of urban residents in southeast coastal area. A dietary survey concerning 1332 persons aged 18 and over was carried out with dietary inquiry and 24-hour recall methods from August to December in 2009. The intakes of cereal, meat, eggs, seafood were enough. The consumption of milk and dairy products, vegetables, fruits was insufficient while the amount of oil was too high. Among them, the intake of milk and dairy products was only 1/3 of suggested values in Dietary Guideline and Balanced Diet Pagoda for Chinese Residents. The intakes of protein, retinol, iron and selenium were sufficient, while those of calcium, thiamine, riboflavin, ascorbic acid were too less than the dietary reference intakes (DRIs). The dietary pattern of urban residents in Ningbo was not reasonable. Nutrition education should be strengthened to guide residents for planning reasonable and balanced diets.

  14. Nutrient adequacy of a very low-fat vegan diet.

    PubMed

    Dunn-Emke, Stacey R; Weidner, Gerdi; Pettengill, Elaine B; Marlin, Ruth O; Chi, Christine; Ornish, Dean M

    2005-09-01

    This study assessed the nutrient adequacy of a very low-fat vegan diet. Thirty-nine men (mean age=65 years) with early stage prostate cancer who chose the "watchful waiting" approach to disease management, were instructed by a registered dietitian and a chef on following a very low-fat (10%) vegan diet with the addition of a fortified soy protein powdered beverage. Three-day food diaries, excluding vitamin and mineral supplements, were analyzed and nutrient values were compared against Dietary Reference Intakes (DRI). Mean dietary intake met the recommended DRIs. On the basis of the Adequate Intake standard, a less than adequate intake was observed for vitamin D. This demonstrates that a very low-fat vegan diet with comprehensive nutrition education emphasizing nutrient-fortified plant foods is nutritionally adequate, with the exception of vitamin D. Vitamin D supplementation, especially for those with limited sun exposure, can help assure nutritional adequacy.

  15. Exposure Assessment in a Single-Walled Carbon Nanotube Primary Manufacturer.

    PubMed

    Kouassi, Serge; Catto, Cyril; Ostiguy, Claude; L'Espérance, Gilles; Kroeger, Jens; Debia, Maximilien

    2017-03-01

    This study was aimed at documenting and characterizing occupational exposure to single-walled carbon nanotubes (SWCNTs) generated in a primary manufacturing plant. It also compared various strategies of exposure monitoring. A 6-day measurement protocol was scheduled (D1-D6) including both (i) quasi-personal monitoring with an array of direct reading instruments (DRIs) and (ii) offline electron microscopy analyses of surface and breathing zone filter-based samples. The first step (D1 and D2) consisted of contamination screenings resulting from the various SWCNT production tasks using a multimetric approach. Surface sampling was also carried out to assess workplace cross-contamination. The second step (D3-D6) focused on the exposure monitoring during recovery/cleaning task, by comparing three personal elemental carbon (EC) measurements [respirable EC using a cyclone following the NIOSH 5040 method (REC-CYC), respirable and thoracic EC using parallel particle impactors [REC-PPI and TEC-PPI, respectively)] and gravimetric mass concentration measurements. DustTrak DRX and electrical low-pressure impactor measurements indicated that particles were released during weighing, transferring, and recovery/cleaning tasks of the manufacturing process. Electron microscopy revealed the presence of agglomerated SWCNTs only during the recovery/cleaning task. REC-CYC concentrations remained under the limits of quantification; REC-PPI showed levels up to 58 µg m-3; and TEC-PPI ranged from 40 to 70 µg m-3. Ratios calculated between gravimetric measurements and estimated DustTrak mass concentrations ranged from 2.8 to 4.9. Cross-contamination appeared to be limited since SWCNTs was only found on surface samples collected close to the reactor in the production room. This case study showed that the DustTrak DRX should be the preferred device among DRIs to identify potential exposure to SWCNTs. However, there is a risk of false positive since it is a non-specific instrument; therefore, the actual release of SWCNTs must be confirmed with scanning electron microscopy/transmission electron microscopy analyses. Besides, using EC measurements as a proxy for SWCNT exposure assessments, as suggested by the NIOSH, is still challenging since interferences can occur with other EC sources such as carbon black, which is also present in the workplace. © The Author 2017. Published by Oxford University Press on behalf of the British Occupational Hygiene Society.

  16. Nutrient reference value: non-communicable disease endpoints--a conference report.

    PubMed

    Lupton, J R; Blumberg, J B; L'Abbe, M; LeDoux, M; Rice, H B; von Schacky, C; Yaktine, A; Griffiths, J C

    2016-03-01

    Nutrition is complex-and seemingly getting more complicated. Most consumers are familiar with "essential nutrients," e.g., vitamins and minerals, and more recently protein and important amino acids. These essential nutrients have nutrient reference values, referred to as dietary reference intakes (DRIs) developed by consensus committees of scientific experts convened by the Institute of Medicine of the National Academy of Sciences, Engineering, and Medicine and carried out by the Food and Nutrition Board. The DRIs comprise a set of four nutrient-based reverence values, the estimated average requirements, the recommended dietary allowances (RDAs), the adequate intakes and the tolerable upper intake levels for micronutrient intakes and an acceptable macronutrient distribution range for macronutrient intakes. From the RDA, the US Food and Drug Administration (FDA) derives a labeling value called the daily value (DV), which appears on the nutrition label of all foods for sale in the US. The DRI reports do not make recommendations about whether the DV labeling values can be set only for what have been defined to date as "essential nutrients." For example, the FDA set a labeling value for "dietary fiber" without having the DV. Nutrient reference values-requirements are set by Codex Alimentarius for essential nutrients, and regulatory bodies in many countries use these Codex values in setting national policy for recommended dietary intakes. However, the focus of this conference is not on essential nutrients, but on the "nonessential nutrients," also termed dietary bioactive components. They can be defined as "Constituents in foods or dietary supplements, other than those needed to meet basic human nutritional needs, which are responsible for changes in health status (Office of Disease Prevention and Health Promotion, Office of Public Health and Science, Department of Health and Human Services in Fed Regist 69:55821-55822, 2004)." Substantial and often persuasive scientific evidence does exist to confirm a relationship between the intake of a specific bioactive constituent and enhanced health conditions or reduced risk of a chronic disease. Further, research on the putative mechanisms of action of various classes of bioactives is supported by national and pan-national government agencies, and academic institutions, as well as functional food and dietary supplement manufacturers. Consumers are becoming educated and are seeking to purchase products containing bioactives, yet there is no evaluative process in place to let the public know how strong the science is behind the benefits or the quantitative amounts needed to achieve these beneficial health effects or to avoid exceeding the upper level (UL). When one lacks an essential nutrient, overt deficiency with concomitant physiological determents and eventually death are expected. The absence of bioactive substances from the diet results in suboptimal health, e.g., poor cellular and/or physiological function, which is relative and not absolute. Regrettably at this time, there is no DRI process to evaluate bioactives, although a recent workshop convened by the National Institutes of Health (Options for Consideration of Chronic Disease Endpoints for Dietary Reference Intakes (DRIs); March 10-11, 2015; http://health.gov/dietaryguidelines/dri/ ) did explore the process to develop DVs for nutrients, the lack of which result in increased risk of chronic disease (non-communicable disease) endpoints. A final report is expected soon. This conference (CRN-International Scientific Symposium; "Nutrient Reference Value-Non-Communicable Disease (NRV-NCD) Endpoints," 20 November in Kronberg, Germany; http://www.crn-i.ch/2015symposium/ ) explores concepts related to the Codex NRV process, the public health opportunities in setting NRVs for bioactive constituents, and further research and details on the specific class of bioactives, n-3 long-chain polyunsaturated fatty acids (also termed omega-3 fatty acids) and their constituents, specifically docosahexaenoic acid and eicosapentaenoic acid.

  17. Impact of food pantry donations on diet of a low-income population.

    PubMed

    Mousa, Tamara Y; Freeland-Graves, Jean H

    2018-04-27

    This cross-sectional study assessed the effect of food donations on total nutrient intake of clients of a food pantry in Central Texas. Nutrient intakes of total, base and food donation diets were estimated for 112 food pantry recipients using specific questionnaires; and then compared to the dietary reference intakes (DRI) and 2015-2020 US Dietary Guidelines. Food donations accounted for more than half of the client's daily intake of energy, carbohydrates, vitamin B 6 , phosphorus, copper and selenium. Yet, daily total intake remained less than their DRIs for carbohydrates, poly-unsaturated fats, dietary fiber, fat soluble vitamins and vitamin C, and was even lower for calcium, magnesium and potassium. Total food intake of clients almost met the US Dietary Guidelines for refined grains, fruits, vegetables, and meat; however, the amount of whole grains and dairy was inadequate. Supplemental foods offered at food pantries are an important resource for improving nutrient intake of low-income populations.

  18. Supplement use contributes to meeting recommended dietary intakes for calcium, magnesium, and vitamin C in four ethnicities of middle-aged and older Americans: the Multi-Ethnic Study of Atherosclerosis.

    PubMed

    Burnett-Hartman, Andrea N; Fitzpatrick, Annette L; Gao, Kun; Jackson, Sharon A; Schreiner, Pamela J

    2009-03-01

    Low intake of nutrients is associated with poor health outcomes. We examined the contribution of dietary supplementation to meeting recommended dietary intakes of calcium, magnesium, potassium, and vitamin C in participants of the Multi-Ethnic Study of Atherosclerosis, a cohort of white, African-American, Hispanic, and Chinese-American participants ages 45 to 84 years. We also assessed the prevalence of intakes above Tolerable Upper Intake Levels (ULs). At the baseline exam in 2000-2001, 2,938 men and 3,299 women completed food frequency questionnaires and provided information about dietary supplementation. We used relative risk regression to estimate the probability of meeting Recommended Dietary Allowances (RDAs) or Adequate Intakes (AIs) in supplement users vs nonusers and Fisher's exact tests to compare the proportion of those exceeding ULs between the two groups. RDAs, AIs, and ULs were defined by the National Academy of Sciences Food and Nutrition Board's Dietary Reference Intakes (DRIs). After adjustment for age and education, the relative risk of meeting RDAs or AIs in supplement-users vs nonusers ranged from 1.9 (1.6, 2.3) in white men to 5.7 (4.1, 8.0) in African-American women for calcium, from 2.5 (1.9, 3.3) in Hispanic men to 5.2 (2.4, 11.2) in Chinese men for magnesium, and from 1.4 (1.3, 1.5) in African-American women to 2.0 (1.7, 2.2) in Chinese men for vitamin C. The relative risks for meeting RDAs for calcium differed significantly by ethnicity (P<0.001) and sex (P<0.001), and by ethnicity for magnesium (P=0.01). The relative risk for each sex/ethnicity strata was close to 1 and did not reach statistical significance at alpha=.05 for potassium. For calcium, 15% of high-dose supplement users exceeded the UL compared with only 2.1% of nonusers. For vitamin C, the percentages were 6.6% and 0%, and for magnesium, 35.3% and 0% (P<0.001 for all). Although supplement use is associated with meeting DRI guidelines for calcium, vitamin C and magnesium, many adults are not meeting the DRI guidelines even with the help of dietary supplements, and the effect of supplementation can vary according to ethnicity and sex. However, supplementation was not significantly associated with meeting DRIs for potassium. Also, high-dose supplement use is associated with intakes above ULs for calcium, magnesium, and vitamin C.

  19. Protein intake trends and conformity with the Dietary Reference Intakes in the United States: analysis of the National Health and Nutrition Examination Survey, 2001-2014.

    PubMed

    Berryman, Claire E; Lieberman, Harris R; Fulgoni, Victor L; Pasiakos, Stefan M

    2018-06-21

    Systematic analysis of dietary protein intake may identify demographic groups within the American population that are not meeting the Dietary Reference Intakes (DRIs). This cross-sectional study analyzed protein intake trends (2001-2014) and evaluated recent conformity to the DRIs (2011-2014) according to age, sex, and race or ethnicity in the US population. Protein intakes and trends during 2-y cycles of NHANES 2001-2014 (n = 57,980; ≥2 y old) were calculated as absolute (grams per day) and relative [grams per kilogram of ideal body weight (IBW) per day] intakes and as a percentage of total energy. Sex and race or ethnicity [Asian, Hispanic, non-Hispanic black (NHB), and non-Hispanic white (NHW)] differences were determined for protein intake and percentage of the population below the Estimated Average Requirement (EAR) and Recommended Dietary Allowance, and above and below the Acceptable Macronutrient Distribution Range (AMDR). Usual protein intakes (mean ± SE) averaged from 55.3 ± 0.9 (children aged 2-3 y) to 88.2 ± 1.1 g/d (adults aged 19-30 y). Protein comprised 14-16% of total energy intakes. Relative protein intakes averaged from 1.10 ± 0.01 (adults aged ≥71 y) to 3.63 ± 0.07 g · kg IBW-1 · d-1 (children aged 2-3 y), and were above the EAR in all demographic groups. Asian and Hispanic populations aged >19 y consumed more relative protein (1.32 ± 0.02 and 1.32 ± 0.02 g · kg IBW-1 · d-1, respectively) than did NHB and NHW (1.18 ± 0.01 g · kg IBW-1 · d-1). Relative protein intakes did not differ by race or ethnicity in the 2-18 y population. Adolescent (aged 14-18 y) females and older (aged ≥71 y) NHB men had the largest population percentages below the EAR (11% and 13%, respectively); <1% of any demographic group had intakes above the AMDR. The majority of the US population exceeds minimum recommendations for protein intake. Protein intake remains well below the upper end of the AMDR, indicating that protein intake, as a percentage of energy intake, is not excessive in the American diet. This trial was registered at www.isrctn.com as ISRCTN76534484.

  20. Hypertension management: rationale for triple therapy based on mechanisms of action.

    PubMed

    Neutel, Joel M; Smith, David H G

    2013-10-01

    An estimated 25% of patients will require 3 antihypertensive agents to achieve blood pressure (BP) control; combination therapy is thus an important strategy in hypertension treatment. This review discusses the triple-therapy combination of an angiotensin receptor blocker (ARB) or direct renin antagonist (DRI) with a calcium channel blocker (CCB) and a diuretic, with a focus on mechanisms of action. Multiple physiologic pathways contribute to hypertension. Combining antihypertensive agents not only better targets the underlying pathways, but also helps blunt compensatory responses that may be triggered by single-agent therapy. DRIs and ARBs target the renin-angiotensin-aldosterone system (RAAS) at the initial and final steps, respectively, and both classes lower BP by reducing the effects of angiotensin-2; however, ARBs may trigger a compensatory increase in renin activity. Dihydropyridine CCBs target L-type calcium channels and lower BP through potent vasodilation, but can trigger compensatory activation of the sympathetic nervous system (SNS) and RAAS. Thiazide diuretics lower BP initially through sodium depletion and plasma volume reduction, followed by total peripheral resistance reduction, but can also trigger compensatory activation of the SNS and RAAS. The combination of an agent targeting the RAAS with a CCB and diuretic is rational, and triple combinations of valsartan/amlodipine/hydrochlorothiazide, olmesartan/amlodipine/hydrochlorothiazide, and aliskiren/amlodipine/hydrochlorothiazide have demonstrated greater effectiveness compared with their respective dual-component combinations. In addition, single-pill, fixed-dose combinations can address barriers to BP control including clinical inertia and poor adherence. Fixed-dose antihypertensive combination products capitalize on complementary mechanisms of action and have been shown to result in improved BP control. © 2012 John Wiley & Sons Ltd.

  1. [Food consumption of children and adolescents living in an area of invasion in Maceio, Alagoas, Brazil].

    PubMed

    da Silva, Juliana Vasconcelos Lyra; Timóteo, Anny Karinny Calheiros Dutra; dos Santos, Célia Dias; Fontes, Gilberto; da Rocha, Eliana Maria Maurício

    2010-03-01

    To assess the food intake of energy, macronutrients and micronutrients related to growth and development in individuals under 16 years of age living in a consolidated invasion settlement in Maceió, Alagoas. The assessment of food intake was carried out by the 24-hour recall method, using a food picture album. Nutritional composition of diets was analysed using the Virtual Nutri-1.0 software. The estimated prevalence of inadequate intake was based on the Dietary Reference (DRIs), adjusted to account for intra-individual variability. The Statistical Package for Social Science (SPSS) version 11.5 was used for data analysis. 5.6% of the subjects studied presented excessive energy intake and for 3.7% it was inadequate. The frequency of excessive energy intake was higher in the 1 to 3 year-old age group (p <0.05), which also showed higher rates of inadequate intake of vitamin A, vitamin E and zinc, and it was the only group in which average consumption of calcium was higher than the adequate intake. Data show that dietary patterns of the individuals studied need adjustments.

  2. Antioxidant intake among Brazilian adults - The Brazilian Osteoporosis Study (BRAZOS): a cross-sectional study

    PubMed Central

    2011-01-01

    Background Antioxidant nutrient intake and the lesser formation of free radicals seem to contribute to chronic diseases. The aim of the present study was to evaluate the intake profile of the main dietary antioxidants in a representative sample of the adult Brazilian population and discuss the main consequences of a low intake of these micronutrients on overall health. Methods The sample comprised 2344 individuals aged 40 years or older from 150 cities and was based on a probabilistic sample from official data. The research was conducted through in-home interviews administered by a team trained for this purpose. Dietary intake information was obtained through 24-h recall. The Nutrition Data System for Research software program was used to analyze data on the intake of vitamins A, C and E, selenium and zinc, which was compared to Dietary Reference Intakes (DRIs). Differences in intake according to sex, anthropometrics, socioeconomic status and region were also evaluated. The SPSS statistical package (version 13) was used for the statistical analysis. P-values < 0.05 were considered significant. Results Higher proportions of low intake in relation to recommended values were found for vitamin E (99.7%), vitamin A (92.4%) and vitamin C (85.1%) in both genders. Intake variations were found between different regions, which may reflect cultural habits. Conclusion These results should lead to the development of public health policies that encourage educational strategies for improving the intake of micronutrients, which are essential to overall health and prevention of non-communicable diseases. PMID:21513578

  3. Calcium and Dairy Products Consumption and Association with Total Hip Bone Mineral Density in Women from Kosovo

    PubMed Central

    Bahtiri, Elton; Islami, Hilmi; Hoxha, Rexhep; Bytyqi, Hasime Qorraj-; Sermaxhaj, Faton; Halimi, Enis

    2014-01-01

    Background and objective: There is paucity of evidence in southeastern Europe and Kosovo regarding dairy products consumption and association with bone mineral density (BMD). Therefore, the objective of present study was to assess calcium intake and dairy products consumption and to investigate relationship with total hip BMD in a Kosovo women sample. Methods: This cross-sectional study included a sample of 185 women divided into respective groups according to total hip BMD. All the study participants completed a food frequency questionnaire and underwent dual-energy X-ray absorptiometry (DEXA) to estimate BMD. Nonparametric tests were performed to compare characteristics of the groups. Results: The average dietary calcium intake was 818.41 mg/day. Only 16.75% of the subjects met calcium recommended dietary reference intakes (DRIs). There were no significant differences between low BMD group and normal BMD group regarding average dietary calcium intake, but it was significantly higher in BMDT3 subgroup than in BMDT2 and BMDT1 subgroups. Conclusions: The results of this study demonstrate significant relationship of daily dietary calcium intake with upper BMD tertile. Further initiatives are warranted from this study to highlight the importance of nutrition education. PMID:25568548

  4. Nutritional adequacy of dietary intake in women with anorexia nervosa.

    PubMed

    Raatz, Susan K; Jahns, Lisa; Johnson, LuAnn K; Crosby, Ross; Mitchell, James E; Crow, Scott; Peterson, Carol; Le Grange, Daniel; Wonderlich, Stephen A

    2015-05-15

    Understanding nutrient intake of anorexia nervosa (AN) patients is essential for the treatment. Therefore, estimates of total energy and nutrient consumption were made in a group of young women (19 to 30 years) with restricting and binge purge subtypes of AN participating in an ecological momentary assessment study. Participants completed three nonconsecutive 24-hour diet recalls. Mean nutrient intakes were stratified by subtype and by quartiles of energy intake and compared to the age specific Dietary Reference Intake (DRI) levels, as well as to the reported intakes from the What We Eat In America (WWEIA) dietary survey 2011-2012. Reported intake was determined for energy, macronutrients, and micronutrients. The mean body mass index (BMI) for all participants was 17.2 ± 0.1 kg/m2. Reported nutrient intake was insufficient for participants in quartiles 1-3 of both AN subtypes when compared to the DRIs. Intake reported by participants in quartile 4 of both subgroups met requirements for most nutrients and even met or exceeded estimated energy needs. Counseling of AN patients should be directed to total food consumption to improve energy intake and to reduce individual nutritional gaps.

  5. Toxic effects of trace elements on newborns and their birth outcomes.

    PubMed

    Tang, Mengling; Xu, Chenye; Lin, Nan; Yin, Shanshan; Zhang, Yongli; Yu, Xinwei; Liu, Weiping

    2016-04-15

    Some trace elements are essential for newborns, their deficiency may cause abnormal biological functions, whereas excessive intakes due to environmental contamination may create adverse health effects. This study was conducted to measure the levels of selected trace elements in Chinese fish consumers by assessing their essentiality and toxicity via colostrum intake in newborns, and evaluated the effects of these trace elements on birth outcomes. Trace elements in umbilical cord serum and colostrum of the studied population were relatively high compared with other populations. The geometric means (GM) of estimated daily intake (EDI, mgday(-1)) of the trace elements were in the safe ranges for infant Dietary Reference Intakes (DRIs) recommended by the United States Food and Drug Administration (FDA). When using total dietary intake (TDI, mgkg(-1)bwday(-1)), zinc (Zn) (0.880mgkg(-1)bwday(-1)) and selenium (Se) (6.39×10(-3)mgkg(-1)bwday(-1)) were above the Reference Doses (RfD), set by the United States Environmental Protection Agency (EPA). Multivariable linear regression analyses showed that Se was negatively correlated with birth outcomes. Our findings suggested that overloading of trace elements due to environmental contamination may contribute to negative birth outcomes. Copyright © 2016 Elsevier B.V. All rights reserved.

  6. Carbon Nanotube Emissions from Arc Discharge Production: Classification of Particle Types with Electron Microscopy and Comparison with Direct Reading Techniques.

    PubMed

    Ludvigsson, Linus; Isaxon, Christina; Nilsson, Patrik T; Tinnerberg, Hakan; Messing, Maria E; Rissler, Jenny; Skaug, Vidar; Gudmundsson, Anders; Bohgard, Mats; Hedmer, Maria; Pagels, Joakim

    2016-05-01

    An increased production and use of carbon nanotubes (CNTs) is occurring worldwide. In parallel, a growing concern is emerging on the adverse effects the unintentional inhalation of CNTs can have on humans. There is currently a debate regarding which exposure metrics and measurement strategies are the most relevant to investigate workplace exposures to CNTs. This study investigated workplace CNT emissions using a combination of time-integrated filter sampling for scanning electron microscopy (SEM) and direct reading aerosol instruments (DRIs). Field measurements were performed during small-scale manufacturing of multiwalled carbon nanotubes using the arc discharge technique. Measurements with highly time- and size-resolved DRI techniques were carried out both in the emission and background (far-field) zones. Novel classifications and counting criteria were set up for the SEM method. Three classes of CNT-containing particles were defined: type 1: particles with aspect ratio length:width >3:1 (fibrous particles); type 2: particles without fibre characteristics but with high CNT content; and type 3: particles with visible embedded CNTs. Offline sampling using SEM showed emissions of CNT-containing particles in 5 out of 11 work tasks. The particles were classified into the three classes, of which type 1, fibrous CNT particles contributed 37%. The concentration of all CNT-containing particles and the occurrence of the particle classes varied strongly between work tasks. Based on the emission measurements, it was assessed that more than 85% of the exposure originated from open handling of CNT powder during the Sieving, mechanical work-up, and packaging work task. The DRI measurements provided complementary information, which combined with SEM provided information on: (i) the background adjusted emission concentration from each work task in different particle size ranges, (ii) identification of the key procedures in each work task that lead to emission peaks, (iii) identification of emission events that affect the background, thereby leading to far-field exposure risks for workers other than the operator of the work task, and (iv) the fraction of particles emitted from each source that contains CNTs. There is an urgent need for a standardized/harmonized method for electron microscopy (EM) analysis of CNTs. The SEM method developed in this study can form the basis for such a harmonized protocol for the counting of CNTs. The size-resolved DRI techniques are commonly not specific enough to selective analysis of CNT-containing particles and thus cannot yet replace offline time-integrated filter sampling followed by SEM. A combination of EM and DRI techniques offers the most complete characterization of workplace emissions of CNTs today. © The Author 2016. Published by Oxford University Press on behalf of the British Occupational Hygiene Society.

  7. A New Platform for Profiling Degradation-Related Impurities Via Exploiting the Opportunities Offered by Ion-Selective Electrodes: Determination of Both Diatrizoate Sodium and Its Cytotoxic Degradation Product.

    PubMed

    Riad, Safaa M; Abd El-Rahman, Mohamed K; Fawaz, Esraa M; Shehata, Mostafa A

    2018-05-01

    Although the ultimate goal of administering active pharmaceutical ingredients (APIs) is to save countless lives, the presence of impurities and/or degradation products in APIs or formulations may cause harmful physiological effects. Today, impurity profiling (i.e., the identity as well as the quantity of impurity in a pharmaceutical) is receiving critical attention from regulatory authorities. Despite the predominant use of spectroscopic and chromatographic methods over electrochemical methods for impurity profiling of APIs, this work investigates the opportunities offered by electroanalytical methods, particularly, ion-selective electrodes (ISEs), for profiling degradation-related impurities (DRIs) compared with conventional spectroscopic and chromatographic methods. For a meaningful comparison, diatrizoate sodium (DTA) was chosen as the anionic X-ray contrast agent based on its susceptibility to deacetylation into its cytotoxic and mutagenic degradation product, 3,5-diamino-2,4,6 triiodobenzoic acid (DTB). This cationic diamino compound can be also detected as an impurity in the final product because it is used as a synthetic precursor for the synthesis of DTA. In this study, four novel sensitive and selective sensors for the determination of both DTA and its cytotoxic degradation products are presented. Sensors I and II were developed for the determination of the anionic drug, DTA, and sensors III and IV were developed for the determination of the cationic cytotoxic impurity. The use of these novel sensors not only provides a stability-indicating method for the selective determination of DTA in the presence of its degradation product, but also permits DRI profiling. Moreover, a great advantage of these proposed ISE systems is their higher sensitivity for the quantification of DTB relative to other spectroscopic and chromatographic methods, so it can measure trace amounts of DTB impurities in DTA bulk powder and pharmaceutical formulation without a need for preliminary separation.

  8. Anthropometric Status and Nutritional Intake in Children (6–9 Years) in Valencia (Spain): The ANIVA Study

    PubMed Central

    Morales-Suárez-Varela, María; Rubio-López, Nuria; Ruso, Candelaria; Llopis-Gonzalez, Agustín; Ruiz-Rojo, Elías; Redondo, Maximino; Pico, Yolanda

    2015-01-01

    The aim of our study was to assess nutritional intake and anthropometric statuses in schoolchildren to subsequently determine nutritional adequacy with Spanish Dietary Reference Intake (DRIs). The ANIVA study, a descriptive cross-sectional study, was conducted in 710 schoolchildren (6–9 years) in 2013–2014 in Valencia (Spain). Children’s dietary intake was measured using 3-day food records, completed by parents. Anthropometric measures (weight and height) were measured according to international standards, and BMI-for-age was calculated and converted into z-scores by WHO-Anthro for age and sex. Nutrient adequacy was assessed using DRI based on estimated average requirement (EAR) or adequate intake (AI). Pearson’s chi-square and Student’s t-test were employed. Of our study group (47.61% boys, 52.39% girls), 53.1% were normoweight and the weight of 46.9% was inadequate; of these, 38.6% had excess body weight (19.6% overweight and 19.0% obesity). We found intakes were lower for biotin, fiber, fluoride, vitamin D (p < 0.016), zinc, iodine, vitamin E, folic acid, calcium and iron (p < 0.017), and higher for lipids, proteins and cholesterol. Our results identify better nutritional adequacy to Spanish recommendations in overweight children. Our findings suggest that nutritional intervention and educational strategies are needed to promote healthy eating in these children and nutritional adequacies. PMID:26694443

  9. Anthropometric Status and Nutritional Intake in Children (6-9 Years) in Valencia (Spain): The ANIVA Study.

    PubMed

    Morales-Suárez-Varela, María; Rubio-López, Nuria; Ruso, Candelaria; Llopis-Gonzalez, Agustín; Ruiz-Rojo, Elías; Redondo, Maximino; Pico, Yolanda

    2015-12-18

    The aim of our study was to assess nutritional intake and anthropometric statuses in schoolchildren to subsequently determine nutritional adequacy with Spanish Dietary Reference Intake (DRIs). The ANIVA study, a descriptive cross-sectional study, was conducted in 710 schoolchildren (6-9 years) in 2013-2014 in Valencia (Spain). Children's dietary intake was measured using 3-day food records, completed by parents. Anthropometric measures (weight and height) were measured according to international standards, and BMI-for-age was calculated and converted into z-scores by WHO-Anthro for age and sex. Nutrient adequacy was assessed using DRI based on estimated average requirement (EAR) or adequate intake (AI). Pearson's chi-square and Student's t-test were employed. Of our study group (47.61% boys, 52.39% girls), 53.1% were normoweight and the weight of 46.9% was inadequate; of these, 38.6% had excess body weight (19.6% overweight and 19.0% obesity). We found intakes were lower for biotin, fiber, fluoride, vitamin D (p < 0.016), zinc, iodine, vitamin E, folic acid, calcium and iron (p < 0.017), and higher for lipids, proteins and cholesterol. Our results identify better nutritional adequacy to Spanish recommendations in overweight children. Our findings suggest that nutritional intervention and educational strategies are needed to promote healthy eating in these children and nutritional adequacies.

  10. Nutritional status of endurance athletes: what is the available information?

    PubMed

    Nogueira, Júlia A D; Da Costa, Teresa H M

    2005-03-01

    Nutritional status is a critical determinant of athletic performance. We question whether currently available studies can give adequate information on nutritional status of endurance athletes. This paper is a critical review of articles published from 1989 to 2003 that investigate nutritional status of endurance athletes. The terms, "nutrition", "diet", or "nutrient", were combined with "endurance athletes" to perform Medline and Pubmed electronic database searches. Two inclusion criteria were considered: (a) study subjects should be adults and (b) articles should report gender-specific values for total energy expenditure and intake of energy, macro and micronutrient from food. Only seven studies fulfilled inclusion criteria. In general, the conclusions of these studies are that endurance athletes have negative energy balance, low intake of carbohydrate, adequate to high intake of protein, and high intake of fat. A critical discussion of the articles' data on vitamins, minerals and trace elements adequacy is conducted using insights and methodology proposed by the newly published assessment and interpretation of Dietary Reference Intakes (DRIs). The studies evaluated give an inappropriate evaluation of the prevalence of adequacy/inadequacy of micronutrient intake among endurance athletes. In this work we indicate potential limitations of existing nutritional data, which reflects the misconceptions found in published literature on nutritional group evaluation. This review stresses the need for a comprehensive and well-conducted nutrition assessment planning to fulfill the existing gap in reliable information about micronutrient adequacy of endurance athletes.

  11. Urinary water-soluble vitamins and their metabolite contents as nutritional markers for evaluating vitamin intakes in young Japanese women.

    PubMed

    Fukuwatari, Tsutomu; Shibata, Katsumi

    2008-06-01

    Little information is available to estimate water-soluble vitamin intakes from urinary vitamins and their metabolite contents as possible nutritional markers. Determination of the relationships between the oral dose and urinary excretion of water-soluble vitamins in human subjects contributes to finding valid nutrition markers of water-soluble vitamin intakes. Six female Japanese college students were given a standard Japanese diet in the first week, the same diet with a synthesized water-soluble vitamin mixture as a diet with approximately onefold vitamin mixture based on Dietary Reference Intakes (DRIs) for Japanese in the second week, with a threefold vitamin mixture in the third week, and a sixfold mixture in the fourth week. Water-soluble vitamins and their metabolites were measured in the 24-h urine collected each week. All urinary vitamins and their metabolite levels except vitamin B(12) increased linearly in a dose-dependent manner, and highly correlated with vitamin intake (r=0.959 for vitamin B(1), r=0.927 for vitamin B(2), r=0.965 for vitamin B(6), r=0.957 for niacin, r=0.934 for pantothenic acid, r=0.907 for folic acid, r=0.962 for biotin, and r=0.952 for vitamin C). These results suggest that measuring urinary water-soluble vitamins and their metabolite levels can be used as good nutritional markers for assessing vitamin intakes.

  12. Nutritional status among postmenopausal osteoporotic women in North West of Iran.

    PubMed

    Hejazi, Jalal; Mohtadinia, Javad; Kolahi, Sousan; Ebrahimi-Mamaghani, Mehrangiz

    2009-01-01

    Osteoporosis is a multifactorial disease and one of the most important modifiable factors in the development and maintenance of bone mass is nutrition. The aim of this study was to determine the nutritional status among osteoporotic postmenopausal women in north west of Iran and compare intake of several nutrients important in terms of bone health with the standard values (DRIs). Bone mineral density of the left proximal femur, the lumbar spine and total hip were measured using dual-energy X-ray absorptiometry. Ninety-seven postmenopausal osteoporotic women were studied. A validated food frequency questionnaire was used to determine food habits and 24-h recall was used to estimate average energy and nutrient intakes. The mean t-score for bone mineral density (BMD) of LS, FN and total hip were -3.15 +/- 0.73, -1.93 +/- 0.86 and -1.92 +/- 0.88, respectively. The percentages of participants receiving adequate intake of calcium, vitamin D and vitamin K were 7.2%, 3.1% and 42.3%, respectively. The mean phosphate to calcium ratio was 1.6 +/- 0.87. BMD of femoral neck and total hip was correlated inversely with the amount of energy obtained from fat and positively with energy intake. Among micronutrients studied, calcium was positively correlated with BMD of total hip. Most of the postmenopausal osteoporotic women in north west of Iran have a considerable deficiency in terms of energy and some micronutrients such as calcium, vitamin D and magnesium, which can be deleterious for bone health.

  13. Therapeutic approaches to slowing the progression of diabetic nephropathy - is less best?

    PubMed

    Vivian, Eva; Mannebach, Chelsea

    2013-03-27

    Angiotensin II receptor blockers (ARBs) and angiotensin-converting enzyme (ACE) inhibitors are known to reduce proteinuria and have been the first-line agents in the management of diabetic nephropathy for the past 20 years. This review covers recent studies that compare the benefit of additional blockage of the renin-angiotensin-aldosterone system through combination therapy with an ACE inhibitor and ARB, or a direct renin inhibitor (DRI), to monotherapy. Primary and review articles that addressed the pathophysiology, diagnosis, and therapeutic options for attenuating the progression of diabetic nephropathy were retrieved through a MEDLINE search (January 1990 to December 2012) and the bibliographies of identified articles were reviewed. English language sources were searched using the following search terms: diabetes mellitus, nephropathy, proteinuria, ACE inhibitors, ARBs, and DRIs. Randomized, placebo-controlled, short- and long-term studies published in peer-reviewed journals that were determined to be methodologically sound, with appropriate statistical analysis of the results, were selected for inclusion in this review. Adult (≥18 years) patients with diabetic nephropathy. Serum creatinine level was used to estimate glomerular filtration rate (GFR). GFR was calculated using the four-variable Modification of Diet in Renal Disease formula. The urine albumin-to-creatinine ratio was measured at baseline and at the conclusion of each study. A value between 3.4 mg/mmol and below 33.9 mg/mmol was defined as microalbuminuria. A value of 33.9 mg/mmol or more (approximately 300 mg/g creatinine) was defined as macroalbuminuria. ACE inhibitors and ARBs are now the mainstay of treatment for diabetic nephropathy. However, combination therapy with an ACE inhibitor and an ARB, or DRI, has not been found to be more effective than monotherapy with an ACE inhibitor or ARB, and may increase the risk of hyperkalemia or acute kidney injury. Both ACE inhibitors and ARBs remain the first-line agents in attenuating the progression of diabetic nephropathy; however, recent studies suggest that combining an ACE inhibitor with an ARB, or combining a DRI with an ACE inhibitor or ARB, may increase adverse events without clinical benefits to offset them.

  14. Assessment of dietary intake in Spanish university students of health sciences.

    PubMed

    Correa-Rodríguez, María; Pocovi, Gabriela; Schmidt-RioValle, Jacqueline; González-Jiménez, Emilio; Rueda-Medina, Blanca

    2018-05-01

    Nutritional intake during early ages has been associated to disease onset later in life. This study aimed to assess dietary intake in Spanish university students of health sciences as compared to national recommended dietary intakes (DRIs). A cross-sectional study was conducted including 585 university students of health sciences aged 18-25 years. Dietary intake was assessed using a 72-h diet recall. A control group was selected from Spanish National Dietary Intake Survey (ENIDE) data. Intake of energy, protein, fat, fatty acids, and cholesterol was significantly lower (p<0.001) in university students compared to controls, while fiber intake showed the opposite trend (p<0.001). Total fat and carbohydrate intake was consistent with recommendations, but protein intake was lower than recommended. Intake of saturated fatty acids (SFAs) was markedly higher than nutrition goals, while intake of monounsaturated fatty acids (MUFAs) was lower. Both students and the reference control group did not reach the optimal dietary intake of iodine and vitamins D and E, while sodium intake was excessive in both groups. Dietary habits of university students were mainly characterized by low intakes of energy, protein, fats, fatty acids, and cholesterol, and high intake of fiber as compared to the general population. Intake of iodine and vitamins D and E was low, while sodium intake was excessive in both university students and the general population. Dietary interventions should be considered to prevent nutritional deficiencies and to ensure a balanced diet. Copyright © 2018 SEEN y SED. Publicado por Elsevier España, S.L.U. All rights reserved.

  15. [Menus offered in long-term care homes: quality of meal service and nutritional analysis].

    PubMed

    Rodríguez Rejón, Ana Isabel; Ruiz López, María Dolores; Malafarina, Vincenzo; Puerta, Antonio; Zuñiga, Antonia; Artacho, Reyes

    2017-06-05

    Institutionalization is a risk factor for malnutrition. Low energy intake and/or nutrient deficiencies are considered to be the main causes. To evaluate the quality of meals and meal service as well as the nutritional value of the main menus (regular menu, menu for diabetics, and pureed menu) offered in three long-term care (LTC) homes located in the metropolitan area of Granada (Spain). Cross-sectional study. A validated "quality of meals and meal service" set of indicators was applied. The menus were assessed by weighed food records on 14 consecutive days. The results were compared with the dietary reference intakes (DRIs) and the recommended number of servings. Important deficiencies in the quality of meals and meal service have been reported. Average energy varies from 1,788 to 2,124 kcal/day in the regular menus, from 1,687 to 1,924 kcal/day in the menus for diabetics, and from 1,518 to 1,639 kcal/day in the pureed menus. Average protein varied from 71.4 to 75.4 g/day, from 72.6 to 76.1 g/day, and from 50.5 to 54.7 g/day, respectively. None of the menus complied with the recommendations for fiber, potassium, magnesium, iodine, vitamin D, vitamin E, folate, nor for vegetables, fruit, milk products, olive oil, legumes, or nuts. It is necessary to ensure the implementation of regular routines for controlling the quality of meals and meal service as well as the nutritional value of the menus offered in LTC homes.

  16. PubMed

    Bissigo Pereira, Fernanda; Miraglia, Fernanda; Barbosa Schmitz, Caroline; Oliveira da Silva, Carmem Lúcia; Ramos Lazzarotto, Alexandre

    2016-02-16

    Objective: To evaluate macro and micronutrients intake of adolescents living with HIV/AIDS in use of antiretroviral therapy and compare it to the Dietary Reference Intakes. Methodology: Cross-sectional study conducted with adolescents of both genders with HIV/AIDS, assessing the dietary composition of macro and micronutrients, using the 24h dietary recall. Results: 39 adolescents, average age of 15 years, 51.3% males. The participants intake of total calories, total fiber (g/d), liposoluble vitamins (A, D, E, K), vitamin B5 (mg/d), vitamin B9 (mg/d), vitamin C (mg/d), calcium (mg/d), phosphorus (mg/d), potassium (mg/d), and magnesium (mg/d) was lower than recommended. The percentages of intake lower than recommended were 79.5% for calories, 82.1% for total fibers, 89.7% for vitamin A, 100% for vitamin D, 87.2% for vitamin E, 100% for vitamin K, 71.8% for vitamin B5, 82.1% for vitamin B9, 76.9% for vitamin C, 92.3% for calcium, 61.5% for phosphorus, 97.4% for potassium, and 76.9% for magnesium. The participants ingested more carbohydrates (g), proteins (g), vitamins B2 (mg/d), B3 (mg/d), B8 (mg/d) and sodium (g/d) than recommended, the percentages above the recommendations being 92.3% for carbohydrates, 64.1% for proteins and vitamin B2, 56.4% for vitamin B3, 82.1% for vitamin B8, and 59% for sodium. The remaining nutrients were within the amounts recommended by the DRIs. Conclusion: Food intake was inadequate as compared to the recommendations of the International Nutrition Guidelines.

  17. [Reference values of folic acid for the Venezuelan population].

    PubMed

    García-Casal, María Nieves; Carias, Diamela; Soto de Sanabria, Ingrid; Victoria López, Ana

    2013-12-01

    The review on folic acid requirements for Venezuela comprise the definitions adopted worldwide known as Dietary Reference Intakes (DRIs) that include Recommended Dietary Allowance (RDA), Estimated Average Requirement (EAR), Adequate Intake (AI) and Tolerable Upper Intake Levels (UL). In contrast with the situation in some countries, that required adjustments in fortification policies in order to avoid excessive folic acid consumption, in Venezuela several studies show an elevated prevalence of deficiency. National evidence at this point is insufficient to establish the recommendation, and as in the 2000 review of the Venezuelan RDAs, the actual recommendations are based on the reported for the United States population. The Recommended Dietary Allowances for Venezuela are 65-80 microg/day for infants less than 1 year old, 150-300 microg/day for children and 400 microg/day for adolescents and adults, increasing to 600 microg/day during pregnancy and to 500 microg/day during lactation. The estimated average requirement is 120-250 microg/day for children, 330 microg/day for adolescents, 320 microg/day for adults, 520 microg/day for pregnancy and 450 microg/day during lactation. The tolerable upper intake levels for folic acid are 300-600 microg/day for children, 800 microg/day for adolescents and 1000 microg/day for adults. During pregnancy and lactation the UL is 800 microg/day for pregnant and lactating women between 14 and 18 years of age, and 1000 microg/day for older pregnant and lactating women. The continuous evaluation of folic acid status is important to design adequate and efficient policies to control both, the deficiency and the excess of folic acid consumption.

  18. Systems Integration Challenges for a National Space Launch System

    NASA Technical Reports Server (NTRS)

    May, Todd A.

    2011-01-01

    System Integration was refined through the complexity and early failures experienced in rocket flight. System Integration encompasses many different viewpoints of the system development. System Integration must ensure consistency in development and operations activities. Human Space Flight tends toward large, complex systems. Understanding the system fs operational and use context is the guiding principle for System Integration: (1) Sizeable costs can be driven into systems by not fully understanding context (2). Adhering to the system context throughout the system fs life cycle is essential to maintaining efficient System Integration. System Integration exists within the System Architecture. Beautiful systems are simple in use and operation -- Block upgrades facilitate manageable steps in functionality evolution. Effective System Integration requires a stable system concept. Communication is essential to system simplicity

  19. Energy Systems Integration Facility Control Room | Energy Systems

    Science.gov Websites

    Integration Facility | NREL Energy Systems Integration Facility Control Room Energy Systems Integration Facility Control Room The Energy Systems Integration Facility control room allows system engineers as the monitoring point for the facility's integrated safety and control systems. Photo of employees

  20. What Is Energy Systems Integration? | Energy Systems Integration Facility |

    Science.gov Websites

    NREL What Is Energy Systems Integration? What Is Energy Systems Integration? Energy systems integration (ESI) is an approach to solving big energy challenges that explores ways for energy systems to Research Community NREL is a founding member of the International Institute for Energy Systems Integration

  1. Subscribe to the Energy Systems Integration Newsletter | Energy Systems

    Science.gov Websites

    Integration Facility | NREL Subscribe to the Energy Systems Integration Newsletter Subscribe to the Energy Systems Integration Newsletter Subscribe to receive regular updates on what's happening at the Energy Systems Integration Facility and in energy systems integration research at NREL and around

  2. Integration mechanisms and hospital efficiency in integrated health care delivery systems.

    PubMed

    Wan, Thomas T H; Lin, Blossom Yen-Ju; Ma, Allen

    2002-04-01

    This study analyzes integration mechanisms that affect system performances measured by indicators of efficiency in integrated delivery systems (IDSs) in the United States. The research question is, do integration mechanisms improve IDSs' efficiency in hospital care? American Hospital Association's Annual Survey (1998) and Dorenfest's Survey on Information Systems in Integrated Healthcare Delivery Systems (1998) were used to conduct the study, using IDS as the unit of analysis. A covariance structure equation model of the effects of system integration mechanisms on IDS performance was formulated and validated by an empirical examination of IDSs. The study sample includes 973 hospital-based integrated health care delivery systems operating in the United States, carried in the list of Dorenfests Survey on Information Systems in Integrated Health care Delivery Systems. The measurement indicators of system integration mechanisms are categorized into six related domains: informatic integration, case management, hybrid physician-hospital integration, forward integration, backward integration, and high tech medical services. The multivariate analysis reveals that integration mechanisms in system operation are positively correlated and positively affect IDSs' efficiency. The six domains of integration mechanisms account for 58.9% of the total variance in hospital performance. The service differentiation strategy such as having more high tech medical services have much stronger influences on efficiency than other integration mechanisms do. The beneficial effects of integration mechanisms have been realized in IDS performance. High efficiency in hospital care can be achieved by employing proper integration strategies in operations.

  3. Energy System Integration Facility Secure Data Center | Energy Systems

    Science.gov Websites

    Integration Facility | NREL Energy System Integration Facility Secure Data Center Energy System Integration Facility Secure Data Center The Energy Systems Integration Facility's Secure Data Center provides

  4. Energy Systems Integration News | Energy Systems Integration Facility |

    Science.gov Websites

    NREL News Energy Systems Integration News A monthly recap of the latest happenings at the Energy Systems Integration Facility and developments in energy systems integration (ESI) research at NREL ; said Vahan Gevorgian, chief engineer with NREL's Power Systems Engineering Center. "Results of

  5. Information integration in health care organizations: The case of a European health system.

    PubMed

    Calciolari, Stefano; Buccoliero, Luca

    2010-01-01

    Information system integration is an important dimension of a company's information system maturity and plays a relevant role in meeting information needs and accountability targets. However, no generalizable evidence exists about whether and how the main integrating technologies influence information system integration in health care organizations. This study examined how integrating technologies are adopted in public health care organizations and chief information officers' (CIOs) perceptions about their influence on information system integration. We used primary data on integrating technologies' adoption and CIOs' perception regarding information system integration in public health care organizations. Analysis of variance (ANOVA) and multinomial logistic regression were used to examine the relationship between CIOs' perception about information system integration and the adopted technologies. Data from 90 health care organizations were available for analyses. Integrating technologies are relatively diffused in public health care organizations, and CIOs seem to shape information system toward integrated architectures. There is a significant positive (although modest, .3) correlation between the number of integrating technologies adopted and the CIO's satisfaction with them. However, regression analysis suggests that organizations covering a broader spectrum of these technologies are less likely to have their CIO reporting main problems concerning integration in the administrative area of the information system compared with the clinical area and where the two areas overlap. Integrating technologies are associated with less perceived problems in the information system administrative area rather than in other areas. Because CIOs play the role of information resource allocators, by influencing information system toward integrated architecture, health care organization leaders should foster cooperation between CIOs and medical staff to enhance information system integration.

  6. Data Entities and Information System Matrix for Integrated Agriculture Information System (IAIS)

    NASA Astrophysics Data System (ADS)

    Budi Santoso, Halim; Delima, Rosa

    2018-03-01

    Integrated Agriculture Information System is a system that is developed to process data, information, and knowledge in Agriculture sector. Integrated Agriculture Information System brings valuable information for farmers: (1) Fertilizer price; (2) Agriculture technique and practise; (3) Pest management; (4) Cultivation; (5) Irrigation; (6) Post harvest processing; (7) Innovation in agriculture processing. Integrated Agriculture Information System contains 9 subsystems. To bring an integrated information to the user and stakeholder, it needs an integrated database approach. Thus, researchers describes data entity and its matrix relate to subsystem in Integrated Agriculture Information System (IAIS). As a result, there are 47 data entities as entities in single and integrated database.

  7. Energy Systems Integration Facility Videos | Energy Systems Integration

    Science.gov Websites

    Facility | NREL Energy Systems Integration Facility Videos Energy Systems Integration Facility Integration Facility NREL + SolarCity: Maximizing Solar Power on Electrical Grids Redefining What's Possible for Renewable Energy: Grid Integration Robot-Powered Reliability Testing at NREL's ESIF Microgrid

  8. Systems Engineering and Integration for Advanced Life Support System and HST

    NASA Technical Reports Server (NTRS)

    Kamarani, Ali K.

    2005-01-01

    Systems engineering (SE) discipline has revolutionized the way engineers and managers think about solving issues related to design of complex systems: With continued development of state-of-the-art technologies, systems are becoming more complex and therefore, a systematic approach is essential to control and manage their integrated design and development. This complexity is driven from integration issues. In this case, subsystems must interact with one another in order to achieve integration objectives, and also achieve the overall system's required performance. Systems engineering process addresses these issues at multiple levels. It is a technology and management process dedicated to controlling all aspects of system life cycle to assure integration at all levels. The Advanced Integration Matrix (AIM) project serves as the systems engineering and integration function for the Human Support Technology (HST) program. AIM provides means for integrated test facilities and personnel for performance trade studies, analyses, integrated models, test results, and validated requirements of the integration of HST. The goal of AIM is to address systems-level integration issues for exploration missions. It will use an incremental systems integration approach to yield technologies, baselines for further development, and possible breakthrough concepts in the areas of technological and organizational interfaces, total information flow, system wide controls, technical synergism, mission operations protocols and procedures, and human-machine interfaces.

  9. Integration of the TDWR and LLWAS wind shear detection system

    NASA Technical Reports Server (NTRS)

    Cornman, Larry

    1991-01-01

    Operational demonstrations of a prototype TDWR/LLWAS (Terminal Doppler Weather Radar/Low Level Wind shear Alarm System) integrated wind shear detection system were conducted. The integration of wind shear detection systems is needed to provide end-users with a single, consensus source of information. A properly implemented integrated system provides wind shear warnings of a higher quality than stand-alone LLWAS or TDWR systems. The algorithmic concept used to generate the TDWR/LLWAS integrated products and several case studies are discussed, indicating the viability and potential of integrated wind shear detection systems. Implications for integrating ground and airborne wind shear detection systems are briefly examined.

  10. NEXT Single String Integration Test Results

    NASA Technical Reports Server (NTRS)

    Soulas, George C.; Patterson, Michael J.; Pinero, Luis; Herman, Daniel A.; Snyder, Steven John

    2010-01-01

    As a critical part of NASA's Evolutionary Xenon Thruster (NEXT) test validation process, a single string integration test was performed on the NEXT ion propulsion system. The objectives of this test were to verify that an integrated system of major NEXT ion propulsion system elements meets project requirements, to demonstrate that the integrated system is functional across the entire power processor and xenon propellant management system input ranges, and to demonstrate to potential users that the NEXT propulsion system is ready for transition to flight. Propulsion system elements included in this system integration test were an engineering model ion thruster, an engineering model propellant management system, an engineering model power processor unit, and a digital control interface unit simulator that acted as a test console. Project requirements that were verified during this system integration test included individual element requirements ; integrated system requirements, and fault handling. This paper will present the results of these tests, which include: integrated ion propulsion system demonstrations of performance, functionality and fault handling; a thruster re-performance acceptance test to establish baseline performance: a risk-reduction PMS-thruster integration test: and propellant management system calibration checks.

  11. Choosing the Right Systems Integration

    NASA Astrophysics Data System (ADS)

    Péči, Matúš; Važan, Pavel

    2014-12-01

    The paper examines systems integration and its main levels at higher levels of control. At present, the systems integration is one of the main aspects participating in the consolidation processes and financial flows of a company. Systems Integration is a complicated emotionconsuming process and it is often a problem to choose the right approach and level of integration. The research focused on four levels of integration, while each of them is characterized by specific conditions. At each level, there is a summary of recommendations and practical experience. The paper also discusses systems integration between the information and MES levels. The main part includes user-level integration where we describe an example of such integration. Finally, we list recommendations and also possible predictions of the systems integration as one of the important factors in the future.

  12. What Is Energy Systems Integration? (Text Version) | Energy Systems

    Science.gov Websites

    Integration Facility | NREL What Is Energy Systems Integration? (Text Version) What Is Energy Systems Integration? (Text Version) This is a text version of the video "What Is Energy Systems

  13. Fuel Distribution Systems | Energy Systems Integration Facility | NREL

    Science.gov Websites

    Fuel Distribution Systems Fuel Distribution Systems The Energy Systems Integration Facility's integrated fuel distribution systems provide natural gas, hydrogen, and diesel throughout its laboratories in two laboratories: the Power Systems Integration Laboratory and the Energy Storage Laboratory. Each

  14. [Reference values of iron, iodine, zinc, selenium, copper, molybdenum, vitamin C, vitamin E, vitamin K, carotenoids and polyphenols for the Venezuelan population].

    PubMed

    García-Casal, Maria Nieves; Landaeta, Maritza; Adrianza de Baptista, Gertrudis; Murillo, Carolain; Rincón, Mariela; Bou Rached, Lizet; Bilbao, Arantza; Anderson, Hazel; García, Doris; Franquiz, Julia; Puche, Rafael; Garcia, Omar; Quintero, Yurimay; Peña-Rosas, Juan Pablo

    2013-12-01

    The review on iron, iodine, zinc, selenium, copper, molybdenum, vitamin C, vitamin E, vitamin K, carotenoids and polyphenols recommendations for Venezuela comprise the definitions adopted worldwide known as Dietary Reference Intakes (DRIs) that include Recommended Dietary Allowance (RDA), Estimated Average Requirement (EAR), Adequate Intake (AI) and Tolerable Upper Intake Levels (UL). The RDA for iron: 11 mg/day for infants < 1 year of age, 7-10 mg/day for children, 8-11 mg/day for males, 8-18 mg/day for females and 27 mg/day during pregnancy. RDA for iodine: 110-130 microg/day for infants, 90-120 microg/ day for children and adolescents, 150 microg/day for adults, 220 microg/ day for pregnancy and 290 microg/day during lactation. RDA Zinc: 2-3 mg/day for infants, 3-5 mg/day for children, 8-11 mg/day for male adolescents and adults, 8-9 mg/day for female adolescents and adults, 12 mg/day during pregnancy and 13 mg/day for lactation. RDA Vitamin C: 40-50 mg/day for infants, 15-45 mg/ day for children, 75 mg/day for male adolescents, 65 mg/day for female adolescents, 90 mg/day for adult males, 75 mg/day for adult females, 80-85 mg/day during pregnancy and 115-120 mg/day during lactation. Recommendations for copper, selenium, molybdenum, vitamins E, K, carotenoids and polyphenols are also presented. These recommendations will help to design adequate and efficient policies that could help to avoid or to treat the consequences derived from the deficiency or the excess of these nutrients.

  15. Comparison of the Mineral Content of Tap Water and Bottled Waters

    PubMed Central

    Azoulay, Arik; Garzon, Philippe; Eisenberg, Mark J

    2001-01-01

    OBJECTIVES Because of growing concern that constituents of drinking water may have adverse health effects, consumption of tap water in North America has decreased and consumption of bottled water has increased. Our objectives were to 1) determine whether North American tap water contains clinically important levels of calcium (Ca2+), magnesium (Mg2+), and sodium (Na+) and 2) determine whether differences in mineral content of tap water and commercially available bottled waters are clinically important. DESIGN We obtained mineral analysis reports from municipal water authorities of 21 major North American cities. Mineral content of tap water was compared with published data regarding commercially available bottled waters and with dietary reference intakes (DRIs). MEASUREMENTS AND MAIN RESULTS Mineral levels varied among tap water sources in North America and among bottled waters. European bottled waters generally contained higher mineral levels than North American tap water sources and North American bottled waters. For half of the tap water sources we examined, adults may fulfill between 8% and 16% of their Ca2+ DRI and between 6% and 31% of their Mg2+ DRI by drinking 2 liters per day. One liter of most moderate mineralization European bottled waters contained between 20% and 58% of the Ca2+ DRI and between 16% and 41% of the Mg2+ DRI in adults. High mineralization bottled waters often contained up to half of the maximum recommended daily intake of Na+. CONCLUSION Drinking water sources available to North Americans may contain high levels of Ca2+, Mg2+, and Na+ and may provide clinically important portions of the recommended dietary intake of these minerals. Physicians should encourage patients to check the mineral content of their drinking water, whether tap or bottled, and choose water most appropriate for their needs. PMID:11318912

  16. Daidzein-rich isoflavone aglycones are potentially effective in reducing hot flashes in menopausal women.

    PubMed

    Khaodhiar, Lalita; Ricciotti, Hope A; Li, Linglin; Pan, Weijun; Schickel, Mary; Zhou, Jinrong; Blackburn, George L

    2008-01-01

    The aim of this study was to determine the effect of DRIs on hot flash symptoms in menopausal women. This was a randomized, double-blind, placebo-controlled trial of menopausal women, aged 38 to 60 years, who experienced 4 to 14 hot flashes per day. After a 1-week run-in period, a total of 190 menopausal women were randomized to receive a placebo or 40 or 60 mg/day of a DRI for 12 weeks. The primary outcome was the mean changes from baseline to week 12 in the frequency of hot flashes recorded in the participant diary. The secondary outcomes included changes in quality of life and hormonal profiles. A total of 147 women (77%) completed the study. It was found that 40 and 60 mg of DRI improved hot flash frequency and severity equally. At 8 weeks hot flash frequency was reduced by 43% in the 40-mg DRI group and by 41% in the 60-mg DRI group, compared with 32% in the placebo group (P = not significant vs placebo). The corresponding numbers for 12 weeks were 52%, 51%, and 39%, respectively (P = 0.07 and 0.09 vs placebo). When comparing the two treatment groups with the placebo group, there were significant reductions in mean daily hot flash frequency. The supplement (either 40 or 60 mg) reduced hot flash frequency by 43% at 8 weeks (P = 0.1) and 52% at 12 weeks (P = 0.048) but did not cause any significant changes in endogenous sex hormones or thyroid hormones. Menopausal quality of life improved in all three groups, although there were no statistically significant differences between groups. DRI supplementation may be an effective and acceptable alternative to hormone treatment for menopausal hot flashes.

  17. Selective Cytotoxicity and Combined Effects of Camptothecin or Paclitaxel with Sodium-R-Alpha Lipoate on A549 Human Non-Small Cell Lung Cancer Cells

    PubMed Central

    Ibrahim, Sherif; Gao, Dayuan; Sinko, Patrick J.

    2013-01-01

    Non-small cell lung cancer (NSCLC) is the most common type of lung cancer and remains the deadliest form of cancer in the US and worldwide. New therapies are highly sought after to improve outcome. The effect of sodium-R-alpha lipoate on camptothecin- and paclitaxel-induced cytotoxicity was evaluated on A549 NSCLC and BEAS-2B ‘normal’ lung epithelial cells. Combination indices (CI) and dose reduction indices (DRI) were investigated by studying the cytotoxicity of sodium-R-alpha lipoate (0–16 mM), camptothecin (0–25 nM) and paclitaxel (0–0.06 nM) alone and in combination. 3-(4,5-dimethylthiazol-2-Yl)-2,5-diphenyltetrazolium-bromide (MTT) was used to assess cytotoxicity. The combinational cytotoxic effects of sodium-R-alpha lipoate with camptothecin or paclitaxel were analyzed using a simulation of dose effects (CompuSyn®3.01). The effects of sodium-R-alpha lipoate on camptothecin- and paclitaxel-induced cytotoxicity varied based on concentrations and treatment times. It was found that sodium-R-alpha lipoate wasn’t cytotoxic towards BEAS-2B cells at any of the concentrations tested. For A549 cells, CIs [(additive (CI=1); synergistic (CI<1); antagonistic (CI>1)] were lower and DRIs were higher for the camptothecin/sodium-R-alpha-lipoate combination (CI=~0.17–1.5; DRI=~2.2–22.6) than the paclitaxel/sodium-R-alpha-lipoate combination (CI=~0.8–9.9; DRI=~0.10–5.8) suggesting that the camptothecin regimen was synergistic and that the addition of sodium-R-alpha lipoate was important for reducing the camptothecin dose and potential for adverse effects. PMID:24063429

  18. Thermal Distribution System | Energy Systems Integration Facility | NREL

    Science.gov Websites

    Thermal Distribution System Thermal Distribution System The Energy Systems Integration Facility's integrated thermal distribution system consists of a thermal water loop connected to a research boiler and . Photo of the roof of the Energy Systems Integration Facility. The thermal distribution bus allows

  19. The Structure and Effectiveness of Health Systems: Exploring the Impact of System Integration in Rural China.

    PubMed

    Wang, Xin; Birch, Stephen; Ma, Huifen; Zhu, Weiming; Meng, Qingyue

    2016-08-12

    Facing the challenges of aging populations, increasing chronic diseases prevalence and health system fragmentation, there have been several pilots of integrated health systems in China. But little is known about their structure, mechanism and effectiveness. The aim of this paper is to analyze health system integration and develop recommendations for achieving integration. Huangzhong and Hualong counties in Qinghai province were studied as study sites, with only Huangzhong having implemented health system integration. Questionnaires, interviews, and health insurance records were sources of data. Social network analysis was employed to analyze integration, through structure measurement and effectiveness evaluation. Health system integration in Huangzhong is higher than in Hualong, so is system effectiveness. The patient referral network in Hualong has more "leapfrog" referrals. The information sharing networks in both counties are larger than the other types of networks. The average distance in the joint training network of Huangzhong is less than in Hualong. Meanwhile, there are deficiencies common to both systems. Both county health systems have strengths and limitations regarding system integration. The use of medical consortia in Huangzhong has contributed to system effectiveness. Future research might consider alternative more context specific models of health system integration.

  20. 48 CFR 209.571-5 - Lead system integrators.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Lead system integrators... Consultant Conflicts of Interest 209.571-5 Lead system integrators. For limitations on contractors acting as lead systems integrators, see 209.570. [75 FR 81913, Dec. 29, 2010] ...

  1. 48 CFR 209.571-5 - Lead system integrators.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Lead system integrators... Consultant Conflicts of Interest 209.571-5 Lead system integrators. For limitations on contractors acting as lead systems integrators, see 209.570. [75 FR 81913, Dec. 29, 2010] ...

  2. 48 CFR 209.571-5 - Lead system integrators.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Lead system integrators... Consultant Conflicts of Interest 209.571-5 Lead system integrators. For limitations on contractors acting as lead systems integrators, see 209.570. [75 FR 81913, Dec. 29, 2010] ...

  3. 48 CFR 209.571-5 - Lead system integrators.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Lead system integrators... Consultant Conflicts of Interest 209.571-5 Lead system integrators. For limitations on contractors acting as lead systems integrators, see 209.570. [75 FR 81913, Dec. 29, 2010] ...

  4. Thermalization threshold in models of 1D fermions

    NASA Astrophysics Data System (ADS)

    Mukerjee, Subroto; Modak, Ranjan; Ramswamy, Sriram

    2013-03-01

    The question of how isolated quantum systems thermalize is an interesting and open one. In this study we equate thermalization with non-integrability to try to answer this question. In particular, we study the effect of system size on the integrability of 1D systems of interacting fermions on a lattice. We find that for a finite-sized system, a non-zero value of an integrability breaking parameter is required to make an integrable system appear non-integrable. Using exact diagonalization and diagnostics such as energy level statistics and the Drude weight, we find that the threshold value of the integrability breaking parameter scales to zero as a power law with system size. We find the exponent to be the same for different models with its value depending on the random matrix ensemble describing the non-integrable system. We also study a simple analytical model of a non-integrable system with an integrable limit to better understand how a power law emerges.

  5. 4. Exterior view of Systems Integration Laboratory Building (T28), looking ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Exterior view of Systems Integration Laboratory Building (T-28), looking northwest. - Air Force Plant PJKS, Systems Integration Laboratory, Systems Integration Laboratory Building, Waterton Canyon Road & Colorado Highway 121, Lakewood, Jefferson County, CO

  6. 3. Exterior view of Systems Integration Laboratory Building (T28), looking ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Exterior view of Systems Integration Laboratory Building (T-28), looking southeast. - Air Force Plant PJKS, Systems Integration Laboratory, Systems Integration Laboratory Building, Waterton Canyon Road & Colorado Highway 121, Lakewood, Jefferson County, CO

  7. 46 CFR 111.105-5 - System integrity.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false System integrity. 111.105-5 Section 111.105-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Hazardous Locations § 111.105-5 System integrity. In order to maintain system integrity, each...

  8. 46 CFR 111.105-5 - System integrity.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false System integrity. 111.105-5 Section 111.105-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Hazardous Locations § 111.105-5 System integrity. In order to maintain system integrity, each...

  9. 46 CFR 111.105-5 - System integrity.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false System integrity. 111.105-5 Section 111.105-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Hazardous Locations § 111.105-5 System integrity. In order to maintain system integrity, each...

  10. Completely integrable 2D Lagrangian systems and related integrable geodesic flows on various manifolds

    NASA Astrophysics Data System (ADS)

    Yehia, Hamad M.

    2013-08-01

    In this study we have formulated a theorem that generates deformations of the natural integrable conservative systems in the plane into integrable systems on Riemannian and other manifolds by introducing additional parameters into their structures. The relation of explicit solutions of the new and the original dynamics to the corresponding Jacobi (Maupertuis) geodesic flow is clarified. For illustration, we apply the result to three concrete examples of the many available integrable systems in the literature. Complementary integrals in those systems are polynomial in velocity with degrees 3, 4 and 6, respectively. As a special case of the first deformed system, a new several-parameter family of integrable mechanical systems (and geodesic flows) on S2 is constructed.

  11. 48 CFR 9.104-6 - Federal Awardee Performance and Integrity Information System.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Performance and Integrity Information System. 9.104-6 Section 9.104-6 Federal Acquisition Regulations System... Contractors 9.104-6 Federal Awardee Performance and Integrity Information System. (a) Before awarding a... Federal Awardee Performance and Integrity Information System (FAPIIS), (available at www.ppirs.gov, then...

  12. 48 CFR 9.104-6 - Federal Awardee Performance and Integrity Information System.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Performance and Integrity Information System. 9.104-6 Section 9.104-6 Federal Acquisition Regulations System... Contractors 9.104-6 Federal Awardee Performance and Integrity Information System. (a) Before awarding a... Federal Awardee Performance and Integrity Information System (FAPIIS), (available at www.ppirs.gov, then...

  13. Man-systems integration and the man-machine interface

    NASA Technical Reports Server (NTRS)

    Hale, Joseph P.

    1990-01-01

    Viewgraphs on man-systems integration and the man-machine interface are presented. Man-systems integration applies the systems' approach to the integration of the user and the machine to form an effective, symbiotic Man-Machine System (MMS). A MMS is a combination of one or more human beings and one or more physical components that are integrated through the common purpose of achieving some objective. The human operator interacts with the system through the Man-Machine Interface (MMI).

  14. Integrating Child Health Information Systems

    PubMed Central

    Hinman, Alan R.; Eichwald, John; Linzer, Deborah; Saarlas, Kristin N.

    2005-01-01

    The Health Resources and Services Administration and All Kids Count (a national technical assistance center fostering development of integrated child health information systems) have been working together to foster development of integrated child health information systems. Activities have included: identification of key elements for successful integration of systems; development of principles and core functions for the systems; a survey of state and local integration efforts; and a conference to develop a common vision for child health information systems to meet medical care and public health needs. We provide 1 state (Utah) as an example that is well on the way to development of integrated child health information systems. PMID:16195524

  15. 75 FR 66131 - Privacy Act of 1974; System of Records

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-27

    ... Integration and Visualization System,'' JUSTICE/FBI-021, which describes the Data Integration and... Liberties Officer. JUSTICE/FBI-021 SYSTEM NAME: Data Integration and Visualization System. * * * * * SYSTEM...

  16. Iron physiological requirements in Chinese adults assessed by the stable isotope labeling technique.

    PubMed

    Cai, Jie; Ren, Tongxiang; Zhang, Yuhui; Wang, Zhilin; Gou, Lingyan; Huang, Zhengwu; Wang, Jun; Piao, Jianhua; Yang, Xiaoguang; Yang, Lichen

    2018-01-01

    Iron is a kind of essential trace mineral in the human body, while the studies on its physiological requirement are very limited recently, especially in China. And most studies were performed with the radioisotope tracer technique, which was harmful to health. This study aimed to first get the value of iron physiological requirements in Chinese adults assessed by the stable isotope labeling technique. Forty-four eligible young Chinese healthy adults were randomly recruited from the Bethune Military Medical College (Shijiazhuang, Hebei, China) between January 2010 and March 2011, and 19 subjects were included in the final data analysis. After adaptive diets and observation, subjects received 58 Fe intravenously. The baseline venous blood sample and general information were collected on day 0. Venous blood samples were also collected on day 14, 30, 60, 100, 120, 150, 240, 330, 425, 515, 605, 767, 1155, respectively. The blood samples were acid digested by a Microwave Digestion System and then analyzed by the MC-ICP-MS and Atomic Absorption Spectroscopy to get the abundance of Fe isotopes and the total iron concentration respectively. The circulation rate (the proportion of blood iron to whole body iron) could be calculated by the intake amount, background content and the peak isotope content. When the abundance changed stably, the iron physiological requirement could be calculated by the iron loss in a period of time. The abundance of 58 Fe reached its peak on day 14, and changed stably from day 425. The average circulation rate was 84%, with no significance difference between the 2 genders. The mean iron requirement in females was 1101.68 μg/d, and the mean requirement adjusted by body weight was 20.69 μg/kg.d. For males, the mean iron requirement was 959.9 μg/d, and the requirement adjusted by body weight was 14.04 μg/kg.d. Our study has obtained the data about the iron physiological requirements of Chinese adults using stable isotope labeling technique, which could provide the basis for adjusting iron DRIs of Chinese people in the future. The trial was registered at the Chinese Clinical Trial Registry (No: ChiCTR-TRC-09000581).

  17. Conceptualizing and measuring integration: findings from the health systems integration study.

    PubMed

    Gillies, R R; Shortell, S M; Anderson, D A; Mitchell, J B; Morgan, K L

    1993-01-01

    Given the pressures for health care reform, interest in the concept of integrated or organized delivery systems as a means to offer more coordinated cost-effective care is growing. This article has two primary objectives: (1) to clarify the different types of integration associated with the notion of an organized delivery system, and (2) to share the results from an ongoing study of 12 organized delivery systems. The findings indicate a moderate level of integration overall, particularly in the areas of culture, financial planning, and strategic planning. The study found that corporate staff respondents perceive their systems to be more integrated and effective than do operating unit managers, and that some functional integration areas are positively associated with both physician-system and clinical integration that, in turn, are positively related to each other. Overall, perceived integration was found to be positively associated with perceived effectiveness.

  18. Reductions in finite-dimensional integrable systems and special points of classical r-matrices

    NASA Astrophysics Data System (ADS)

    Skrypnyk, T.

    2016-12-01

    For a given 𝔤 ⊗ 𝔤-valued non-skew-symmetric non-dynamical classical r-matrices r(u, v) with spectral parameters, we construct the general form of 𝔤-valued Lax matrices of finite-dimensional integrable systems satisfying linear r-matrix algebra. We show that the reduction in the corresponding finite-dimensional integrable systems is connected with "the special points" of the classical r-matrices in which they become degenerated. We also propose a systematic way of the construction of additional integrals of the Lax-integrable systems associated with the symmetries of the corresponding r-matrices. We consider examples of the Lax matrices and integrable systems that are obtained in the framework of the general scheme. Among them there are such physically important systems as generalized Gaudin systems in an external magnetic field, ultimate integrable generalization of Toda-type chains (including "modified" or "deformed" Toda chains), generalized integrable Jaynes-Cummings-Dicke models, integrable boson models generalizing Bose-Hubbard dimer models, etc.

  19. 48 CFR 1334.202 - Integrated baseline reviews.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 1334.202 Integrated baseline reviews. An Integrated Baseline Review shall be conducted when an Earned Value Management System... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Integrated baseline...

  20. 48 CFR 1334.202 - Integrated baseline reviews.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 1334.202 Integrated baseline reviews. An Integrated Baseline Review shall be conducted when an Earned Value Management System... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Integrated baseline...

  1. 48 CFR 1334.202 - Integrated baseline reviews.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 1334.202 Integrated baseline reviews. An Integrated Baseline Review shall be conducted when an Earned Value Management System... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Integrated baseline...

  2. 48 CFR 1334.202 - Integrated baseline reviews.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 1334.202 Integrated baseline reviews. An Integrated Baseline Review shall be conducted when an Earned Value Management System... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Integrated baseline...

  3. 48 CFR 1334.202 - Integrated baseline reviews.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 1334.202 Integrated baseline reviews. An Integrated Baseline Review shall be conducted when an Earned Value Management System... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Integrated baseline...

  4. System integration case study : FAST-TRAC : preliminary IV deliverable : #2-systems integration case study

    DOT National Transportation Integrated Search

    1999-02-12

    This report focuses on the system integration aspect of the Transportation Information Management System (TIMS), a component of the FAST-TRAC project. The TIMS functions as the center of a communications network which integrates advanced traffic cont...

  5. NREL Leads Energy Systems Integration, Continuum Magazine: Issue 4 (Book)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    2013-04-01

    Continuum Magazine showcases NREL's latest and most impactful clean energy innovations. This issue, 'NREL Leads Energy Systems Integration' explores the discipline of energy systems integration, in particular the role of the laboratory's new, one-of-a-kind Energy System Integration Facility. NREL scientists, engineers, and analysts deeply understand the fundamental science and technologies underpinning major energy producing and consuming systems, as well as the transmission infrastructure and communications and data networks required to integrate energy systems at all scales.

  6. Integration of Systems with Varying Levels of Autonomy (Integration de Systemes a Niveau d’Autonomie Variable)

    DTIC Science & Technology

    2008-09-01

    SCI-144 Integration of Systems with Varying Levels of Autonomy (Intégration de systèmes à niveau d’autonomie variable) This Report was...prepared by Task Group SCI-144 on “ System -Level Integration of Control plus Automation” and has been sponsored by the Systems Concepts and Integration... Systems with Varying Levels of Autonomy (Intégration de systèmes à niveau d’autonomie variable) This Report was prepared by Task Group SCI-144 on

  7. Integration of Systems with Varying Levels of Autonomy (Integration de systemes a niveau d’autonomie variable)

    DTIC Science & Technology

    2008-09-01

    SCI-144 Integration of Systems with Varying Levels of Autonomy (Intégration de systèmes à niveau d’autonomie variable) This Report was...prepared by Task Group SCI-144 on “ System -Level Integration of Control plus Automation” and has been sponsored by the Systems Concepts and Integration... Systems with Varying Levels of Autonomy (Intégration de systèmes à niveau d’autonomie variable) This Report was prepared by Task Group SCI-144 on

  8. 48 CFR 3052.209-74 - Limitations on contractors acting as lead system integrators.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... acting as lead system integrators. 3052.209-74 Section 3052.209-74 Federal Acquisition Regulations System... contractors acting as lead system integrators. As prescribed in (HSAR) 48 CFR 3009.570-4(a), use the following provision: LIMITATIONS ON CONTRACTORS ACTING AS LEAD SYSTEM INTEGRATORS (JUL 2010) (a) Definitions. “Direct...

  9. 48 CFR 3052.209-74 - Limitations on contractors acting as lead system integrators.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... acting as lead system integrators. 3052.209-74 Section 3052.209-74 Federal Acquisition Regulations System... contractors acting as lead system integrators. As prescribed in (HSAR) 48 CFR 3009.570-4(a), use the following provision: LIMITATIONS ON CONTRACTORS ACTING AS LEAD SYSTEM INTEGRATORS (JUL 2010) (a) Definitions. “Direct...

  10. Energy Systems Integration News | Energy Systems Integration Facility |

    Science.gov Websites

    -matter experts to develop cyber-physical systems security testing methodologies and resilience best the Energy Systems Integration Facility as part of NREL's work with SolarCity and the Hawaiian Electric Companies. Photo by Amy Glickson, NREL Welcome to Energy Systems Integration News, NREL's monthly

  11. Ten key principles for successful health systems integration.

    PubMed

    Suter, Esther; Oelke, Nelly D; Adair, Carol E; Armitage, Gail D

    2009-01-01

    Integrated health systems are considered part of the solution to the challenge of sustaining Canada's healthcare system. This systematic literature review was undertaken to guide decision-makers and others to plan for and implement integrated health systems. This review identified 10 universal principles of successfully integrated healthcare systems that may be used by decision-makers to assist with integration efforts. These principles define key areas for restructuring and allow organizational flexibility and adaptation to local context. The literature does not contain a one-size-fits-all model or process for successful integration, nor is there a firm empirical foundation for specific integration strategies and processes.

  12. Integrated Personnel and Pay System-Army Increment 2 (IPPS-A Inc 2)

    DTIC Science & Technology

    2016-03-01

    2016 Major Automated Information System Annual Report Integrated Personnel and Pay System-Army Increment 2 (IPPS-A Inc 2) Defense Acquisition...703-325-3747 DSN Phone: 865-2915 DSN Fax: 221-3747 Date Assigned: May 2, 2014 Program Information Program Name Integrated Personnel and Pay System...Program Description The Integrated Personnel and Pay System-Army (IPPS-A) will provide the Army with an integrated, multi-Component (Active, National

  13. Experience Of Implementing The Integrated Management System In Manufacturing Companies In Slovakia

    NASA Astrophysics Data System (ADS)

    Lestyánszka Škůrková, Katarína; Kučerová, Marta; Fidlerová, Helena

    2015-06-01

    In corporate practice, the term of Integrated Management System means a system the aim of which is to manage an organization regarding the quality, environment, health and safety at work. In the first phase of the VEGA project No. 1/0448/13 "Transformation of ergonomics program into the company management structure through interaction and utilization QMS, EMS, HSMS", we focused on obtaining information about the way or procedure of implementing the integrated management systems in manufacturing companies in Slovakia. The paper considers characteristics of integrated management system, specifies the possibilities for successive integration of the management systems and also describes the essential aspects of the practical implementation of integrated management systems in companies in Slovakia.

  14. Is health systems integration being advanced through Local Health District planning?

    PubMed

    Saunders, Carla; Carter, David J

    2017-05-01

    Objective Delivering genuine integrated health care is one of three strategic directions in the New South Wales (NSW) Government State Health Plan: Towards 2021. This study investigated the current key health service plan of each NSW Local Health District (LHD) to evaluate the extent and nature of health systems integration strategies that are currently planned. Methods A scoping review was conducted to identify common key principles and practices for successful health systems integration to enable the development of an appraisal tool to content assess LHD strategic health service plans. Results The strategies that are planned for health systems integration across LHDs focus most often on improvements in coordination, health care access and care delivery for complex at-risk patients across the care continuum by both state- and commonwealth-funded systems, providers and agencies. The most common reasons given for integrated activities were to reduce avoidable hospitalisation, avoid inappropriate emergency department attendance and improve patient care. Conclusions Despite the importance of health systems integration and finding that all NSW LHDs have made some commitment towards integration in their current strategic health plans, this analysis suggests that health systems integration is in relatively early development across NSW. What is known about the topic? Effective approaches to managing complex chronic diseases have been found to involve health systems integration, which necessitates sound communication and connection between healthcare providers across community and hospital settings. Planning based on current health systems integration knowledge to ensure the efficient use of scarce resources is a responsibility of all health systems. What does this paper add? Appropriate planning and implementation of health systems integration is becoming an increasingly important expectation and requirement of effective health systems. The present study is the first of its kind to assess the planned activity in health systems integration in the NSW public health system. NSW health districts play a central role in health systems integration; each health service plan outlines the strategic directions for the development and delivery of all state-funded services across each district for the coming years, equating to hundreds of millions of dollars in health sector funding. The inclusion of effective health systems integration strategies allows Local Health Districts to lay the foundation for quality patient outcomes and long-term financial sustainability despite projected increases in demand for health services. What are the implications for practice? Establishing robust ongoing mechanisms for effective health systems integration is now a necessary part of health planning. The present study identifies several key areas and strategies that are wide in scope and indicative of efforts towards health systems integration, which may support Local Health Districts and other organisations in systematic planning and implementation.

  15. Energy Systems Integration News | Energy Systems Integration Facility |

    Science.gov Websites

    DOE-funded research projects that are integrating cybersecurity controls with power systems principles Management, a hardware and software system that mimics the communications, power systems, and cybersecurity

  16. Integrated control system for electron beam processes

    NASA Astrophysics Data System (ADS)

    Koleva, L.; Koleva, E.; Batchkova, I.; Mladenov, G.

    2018-03-01

    The ISO/IEC 62264 standard is widely used for integration of the business systems of a manufacturer with the corresponding manufacturing control systems based on hierarchical equipment models, functional data and manufacturing operations activity models. In order to achieve the integration of control systems, formal object communication models must be developed, together with manufacturing operations activity models, which coordinate the integration between different levels of control. In this article, the development of integrated control system for electron beam welding process is presented as part of a fully integrated control system of an electron beam plant, including also other additional processes: surface modification, electron beam evaporation, selective melting and electron beam diagnostics.

  17. A large scale software system for simulation and design optimization of mechanical systems

    NASA Technical Reports Server (NTRS)

    Dopker, Bernhard; Haug, Edward J.

    1989-01-01

    The concept of an advanced integrated, networked simulation and design system is outlined. Such an advanced system can be developed utilizing existing codes without compromising the integrity and functionality of the system. An example has been used to demonstrate the applicability of the concept of the integrated system outlined here. The development of an integrated system can be done incrementally. Initial capabilities can be developed and implemented without having a detailed design of the global system. Only a conceptual global system must exist. For a fully integrated, user friendly design system, further research is needed in the areas of engineering data bases, distributed data bases, and advanced user interface design.

  18. Meeting of Experts on NASA's Unmanned Aircraft System (UAS) Integration in the National Airspace Systems (NAS) Project

    NASA Technical Reports Server (NTRS)

    Wolfe, Jean; Bauer, Jeff; Bixby, C.J.; Lauderdale, Todd; Shively, Jay; Griner, James; Hayhurst, Kelly

    2010-01-01

    Topics discussed include: Aeronautics Research Mission Directorate Integrated Systems Research Program (ISRP) and UAS Integration in the NAS Project; UAS Integration into the NAS Project; Separation Assurance and Collision Avoidance; Pilot Aircraft Interface Objectives/Rationale; Communication; Certification; and Integrated Tests and Evaluations.

  19. System Engineering of Photonic Systems for Space Application

    NASA Technical Reports Server (NTRS)

    Watson, Michael D.; Pryor, Jonathan E.

    2014-01-01

    The application of photonics in space systems requires tight integration with the spacecraft systems to ensure accurate operation. This requires some detailed and specific system engineering to properly incorporate the photonics into the spacecraft architecture and to guide the spacecraft architecture in supporting the photonics devices. Recent research in product focused, elegant system engineering has led to a system approach which provides a robust approach to this integration. Focusing on the mission application and the integration of the spacecraft system physics incorporation of the photonics can be efficiently and effectively accomplished. This requires a clear understanding of the driving physics properties of the photonics device to ensure proper integration with no unintended consequences. The driving physics considerations in terms of optical performance will be identified for their use in system integration. Keywords: System Engineering, Optical Transfer Function, Optical Physics, Photonics, Image Jitter, Launch Vehicle, System Integration, Organizational Interaction

  20. Shared mental models of integrated care: aligning multiple stakeholder perspectives.

    PubMed

    Evans, Jenna M; Baker, G Ross

    2012-01-01

    Health service organizations and professionals are under increasing pressure to work together to deliver integrated patient care. A common understanding of integration strategies may facilitate the delivery of integrated care across inter-organizational and inter-professional boundaries. This paper aims to build a framework for exploring and potentially aligning multiple stakeholder perspectives of systems integration. The authors draw from the literature on shared mental models, strategic management and change, framing, stakeholder management, and systems theory to develop a new construct, Mental Models of Integrated Care (MMIC), which consists of three types of mental models, i.e. integration-task, system-role, and integration-belief. The MMIC construct encompasses many of the known barriers and enablers to integrating care while also providing a comprehensive, theory-based framework of psychological factors that may influence inter-organizational and inter-professional relations. While the existing literature on integration focuses on optimizing structures and processes, the MMIC construct emphasizes the convergence and divergence of stakeholders' knowledge and beliefs, and how these underlying cognitions influence interactions (or lack thereof) across the continuum of care. MMIC may help to: explain what differentiates effective from ineffective integration initiatives; determine system readiness to integrate; diagnose integration problems; and develop interventions for enhancing integrative processes and ultimately the delivery of integrated care. Global interest and ongoing challenges in integrating care underline the need for research on the mental models that characterize the behaviors of actors within health systems; the proposed framework offers a starting point for applying a cognitive perspective to health systems integration.

  1. Extent of Integration of Priority Interventions into General Health Systems: A Case Study of Neglected Tropical Diseases Programme in the Western Region of Ghana.

    PubMed

    Mensah, Ernest O; Aikins, Moses K; Gyapong, Margaret; Anto, Francis; Bockarie, Moses J; Gyapong, John O

    2016-05-01

    The global health system has a large arsenal of interventions, medical products and technologies to address current global health challenges. However, identifying the most effective and efficient strategies to deliver these resources to where they are most needed has been a challenge. Targeted and integrated interventions have been the main delivery strategies. However, the health system discourse increasingly favours integrated strategies in the context of functionally merging targeted interventions with multifunctional health care delivery systems with a focus on strengthening country health systems to deliver needed interventions. Neglected Tropical Diseases (NTD) have been identified to promote and perpetuate poverty hence there has been global effort to combat these diseases. The Neglected Tropical Diseases Programme (NTDP) in Ghana has a national programme team and office, however, it depends on the multifunctional health delivery system at the regional and district level to implement interventions. The NTDP seeks further health system integration to accelerate achievement of coverage targets. The study estimated the extent of integration of the NTDP at the national, regional and district levels to provide evidence to guide further integration. The research design was a descriptive case study that interviewed key persons involved in the programme at the three levels of the health system as well as extensive document review. Integration was assessed on two planes-across health system functions-stewardship and governance, financing, planning, service delivery, monitoring and evaluation and demand generation; and across three administrative levels of the health system-national, regional and district. A composite measure of integration designated Cumulative Integration Index (CII) with a range of 0.00-1.00 was used to estimate extent of integration at the three levels of the health system. Service delivery was most integrated while financing and planning were least integrated. Extent of integration was partial at all levels of the health system with a CII of 0.48-0.68; however it was higher at the district compared to the national and regional levels. To ensure further integration of the NTDP, planning and finance management activities must be decentralized to involve regional and district levels of the health system. The study provides an empirical measure of extent of integration and indicators to guide further integration.

  2. Enterprise Information System Integration Technology

    NASA Astrophysics Data System (ADS)

    Tanaka, Tetsuo; Yumoto, Masaki; Itsuki, Rei

    In the current rapidly changing business environment, companies need to be efficient and agile to survive and thrive. That is why flexible systems integration is urgent and crucial concern for any enterprise. For the meanwhile, systems integration technology is getting more complicated, and middleware types are beginning blur for decades. We sort system integration into four different types, “Delayed Federation", “Real-time Federation", “Delayed Integration", and “Real-time Integration". We also outline appropriate technology and architecture for each type.

  3. 9. Exterior view, Test Cell 7, Systems Integration Laboratory Building ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. Exterior view, Test Cell 7, Systems Integration Laboratory Building (T-28), looking southwest. The enclosure discussed in CO-88-B-8 is at the right. - Air Force Plant PJKS, Systems Integration Laboratory, Systems Integration Laboratory Building, Waterton Canyon Road & Colorado Highway 121, Lakewood, Jefferson County, CO

  4. 78 FR 7334 - Port Authority Access to Facility Vulnerability Assessments and the Integration of Security Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-01

    ... to Facility Vulnerability Assessments and the Integration of Security Systems AGENCY: Coast Guard...-sharing measures. Security System Integration Alternatives Require each MTSA-regulated facility owner or... other forms of security system integration. Information Requested 1. We request comments on the...

  5. Newly Branded Energy Systems Integration Group Joins International

    Science.gov Websites

    research fellow at NREL. Likewise, UVIG sees opportunity in partnering with iiESI. The international Group Joins International Institute for Energy Systems Integration Newly Branded Energy Systems Integration Group Joins International Institute for Energy Systems Integration March 22, 2018 The world of

  6. 1. Exterior view of Systems Integration Laboratory Building (T28), looking ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Exterior view of Systems Integration Laboratory Building (T-28), looking northeast. The taller of the two gantries on the left houses Test Cell 6 (fuel), while the shorter gantry on the right houses Test Cell 7 (oxidizer). This structure serves as the functional center of the Systems Integration Laboratory complex for testing, handling, and storage of the Titan II's hydrazine - and nitrogen tetroxide-based fuel system propellants. - Air Force Plant PJKS, Systems Integration Laboratory, Systems Integration Laboratory Building, Waterton Canyon Road & Colorado Highway 121, Lakewood, Jefferson County, CO

  7. An Optimized Integrator Windup Protection Technique Applied to a Turbofan Engine Control

    NASA Technical Reports Server (NTRS)

    Watts, Stephen R.; Garg, Sanjay

    1995-01-01

    This paper introduces a new technique for providing memoryless integrator windup protection which utilizes readily available optimization software tools. This integrator windup protection synthesis provides a concise methodology for creating integrator windup protection for each actuation system loop independently while assuring both controller and closed loop system stability. The individual actuation system loops' integrator windup protection can then be combined to provide integrator windup protection for the entire system. This technique is applied to an H(exp infinity) based multivariable control designed for a linear model of an advanced afterburning turbofan engine. The resulting transient characteristics are examined for the integrated system while encountering single and multiple actuation limits.

  8. Supervisory Control and Data Acquisition System | Energy Systems

    Science.gov Websites

    Integration Facility | NREL Supervisory Control and Data Acquisition System Supervisory Control supervisory control and data acquisition (SCADA) system monitors and controls safety systems and gathers real Energy Systems Integration Facility control room. The Energy Systems Integration Facility's SCADA system

  9. Flight-determined benefits of integrated flight-propulsion control systems

    NASA Technical Reports Server (NTRS)

    Stewart, James F.; Burcham, Frank W., Jr.; Gatlin, Donald H.

    1992-01-01

    The fundamentals of control integration for propulsion are reviewed giving practical illustrations of its use to demonstrate the advantages of integration. Attention is given to the first integration propulsion-control systems (IPCSs) which was developed for the F-111E, and the integrated controller design is described that NASA developed for the YF-12C aircraft. The integrated control systems incorporate a range of aircraft components including the engine, inlet controls, autopilot, autothrottle, airdata, navigation, and/or stability-augmentation systems. Also described are emergency-control systems, onboard engine optimization, and thrust-vectoring control technologies developed for the F-18A and the F-15. Integrated flight-propulsion control systems are shown to enhance the thrust, range, and survivability of the aircraft while reducing fuel consumption and maintenance.

  10. A service platform architecture design towards a light integration of heterogeneous systems in the wellbeing domain.

    PubMed

    Yang, Yaojin; Ahtinen, Aino; Lahteenmaki, Jaakko; Nyman, Petri; Paajanen, Henrik; Peltoniemi, Teijo; Quiroz, Carlos

    2007-01-01

    System integration is one of the major challenges for building wellbeing or healthcare related information systems. In this paper, we are going to share our experiences on how to design a service platform called Nuadu service platform, for providing integrated services in occupational health promotion and health risk management through two heterogeneous systems. Our design aims for a light integration covering the layers, from data through service up to presentation, while maintaining the integrity of the underlying systems.

  11. Polarity management: the key challenge for integrated health systems.

    PubMed

    Burns, L R

    1999-01-01

    Integrated health systems are confronted with numerous dilemmas that must be managed. Many of these dilemmas are an inherent part of the system's structure, given that multiple competing hospitals, medical groups, and (sometimes) health plans are often under one organizational roof. This article presents an analysis of these dilemmas--referred to in the management literature as polarities--as they are found in six integrated health systems in Illinois. The nine polarities that must be managed include (1) hospital systems that want to be organizations of physicians; (2) system expansion by growing the physician component; (3) system centralization and physician decentralization; (4) centripetal and centrifugal forces involving physicians; (5) system objectives and physician interests; (6) system centralization and hospital decentralization; (7) primary care physicians and specialists; (8) physician autonomy via collectivization; and (9) vertical and virtual integration. The article identifies some of the solutions to the polarities that have been enacted by systems. In general, executives and physicians in integrated health systems must attend to the processes of integration as much as or more than the structures of integration.

  12. Flight-determined benefits of integrated flight-propulsion control systems

    NASA Technical Reports Server (NTRS)

    Stewart, James F.; Burcham, Frank W., Jr.; Gatlin, Donald H.

    1992-01-01

    Over the last two decades, NASA has conducted several experiments in integrated flight-propulsion control. Benefits have included improved maneuverability; increased thrust, range, and survivability; reduced fuel consumption; and reduced maintenance. This paper presents the basic concepts for control integration, examples of implementation, and benefits. The F-111E experiment integrated the engine and inlet control systems. The YF-12C incorporated an integral control system involving the inlet, autopilot, autothrottle, airdata, navigation, and stability augmentation systems. The F-15 research involved integration of the engine, flight, and inlet control systems. Further extension of the integration included real-time, onboard optimization of engine, inlet, and flight control variables; a self-repairing flight control system; and an engines-only control concept for emergency control. The F-18A aircraft incorporated thrust vectoring integrated with the flight control system to provide enhanced maneuvering at high angles of attack. The flight research programs and the resulting benefits of each program are described.

  13. Energy Systems Integration News | Energy Systems Integration Facility |

    Science.gov Websites

    Renewable Generation Integration Study (ERGIS), looks ahead to the year 2026 and examines how the Eastern accurately modeling the entire system at five-minute intervals for an entire year has never even been Integrated Network Testbed for Energy Grid Research and Technology Experimentation (INTEGRATE) project, up to

  14. Unmanned Aircraft Systems (UAS) Integration in the National Airspace System (NAS) Project Subcommittee Final

    NASA Technical Reports Server (NTRS)

    Johnson, Chuck; Griner, James H.; Hayhurst, Kelly J.; Shively, Robert J.; Consiglio, Maria; Muller, Eric; Murphy, James; Kim, Sam

    2012-01-01

    UAS Integration in the NAS Project overview with details from each of the subprojects. Subprojects include: Communications, Certification, Integrated Test and Evaluation, Human Systems Integration, and Separation Assurance/Sense and Avoid Interoperability.

  15. Extent of Integration of Priority Interventions into General Health Systems: A Case Study of Neglected Tropical Diseases Programme in the Western Region of Ghana

    PubMed Central

    Mensah, Ernest O.; Aikins, Moses K.; Gyapong, Margaret; Anto, Francis; Bockarie, Moses J.; Gyapong, John O.

    2016-01-01

    Background The global health system has a large arsenal of interventions, medical products and technologies to address current global health challenges. However, identifying the most effective and efficient strategies to deliver these resources to where they are most needed has been a challenge. Targeted and integrated interventions have been the main delivery strategies. However, the health system discourse increasingly favours integrated strategies in the context of functionally merging targeted interventions with multifunctional health care delivery systems with a focus on strengthening country health systems to deliver needed interventions. Neglected Tropical Diseases (NTD) have been identified to promote and perpetuate poverty hence there has been global effort to combat these diseases. The Neglected Tropical Diseases Programme (NTDP) in Ghana has a national programme team and office, however, it depends on the multifunctional health delivery system at the regional and district level to implement interventions. The NTDP seeks further health system integration to accelerate achievement of coverage targets. The study estimated the extent of integration of the NTDP at the national, regional and district levels to provide evidence to guide further integration. Methodology/Principal Findings The research design was a descriptive case study that interviewed key persons involved in the programme at the three levels of the health system as well as extensive document review. Integration was assessed on two planes—across health system functions–stewardship and governance, financing, planning, service delivery, monitoring and evaluation and demand generation; and across three administrative levels of the health system–national, regional and district. A composite measure of integration designated Cumulative Integration Index (CII) with a range of 0.00–1.00 was used to estimate extent of integration at the three levels of the health system. Service delivery was most integrated while financing and planning were least integrated. Extent of integration was partial at all levels of the health system with a CII of 0.48–0.68; however it was higher at the district compared to the national and regional levels. Conclusions/Significance To ensure further integration of the NTDP, planning and finance management activities must be decentralized to involve regional and district levels of the health system. The study provides an empirical measure of extent of integration and indicators to guide further integration. PMID:27203854

  16. Reframing the challenges to integrated care: a complex-adaptive systems perspective.

    PubMed

    Tsasis, Peter; Evans, Jenna M; Owen, Susan

    2012-01-01

    Despite over two decades of international experience and research on health systems integration, integrated care has not developed widely. We hypothesized that part of the problem may lie in how we conceptualize the integration process and the complex systems within which integrated care is enacted. This study aims to contribute to discourse regarding the relevance and utility of a complex-adaptive systems (CAS) perspective on integrated care. In the Canadian province of Ontario, government mandated the development of fourteen Local Health Integration Networks in 2006. Against the backdrop of these efforts to integrate care, we collected focus group data from a diverse sample of healthcare professionals in the Greater Toronto Area using convenience and snowball sampling. A semi-structured interview guide was used to elicit participant views and experiences of health systems integration. We use a CAS framework to describe and analyze the data, and to assess the theoretical fit of a CAS perspective with the dominant themes in participant responses. Our findings indicate that integration is challenged by system complexity, weak ties and poor alignment among professionals and organizations, a lack of funding incentives to support collaborative work, and a bureaucratic environment based on a command and control approach to management. Using a CAS framework, we identified several characteristics of CAS in our data, including diverse, interdependent and semi-autonomous actors; embedded co-evolutionary systems; emergent behaviours and non-linearity; and self-organizing capacity. One possible explanation for the lack of systems change towards integration is that we have failed to treat the healthcare system as complex-adaptive. The data suggest that future integration initiatives must be anchored in a CAS perspective, and focus on building the system's capacity to self-organize. We conclude that integrating care requires policies and management practices that promote system awareness, relationship-building and information-sharing, and that recognize change as an evolving learning process rather than a series of programmatic steps.

  17. 2. Exterior view of Systems Integration Laboratory Building (T28), looking ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Exterior view of Systems Integration Laboratory Building (T-28), looking southwest. The low-lying concrete Signal Transfer Building (T-28A) is located in the immediate foreground. - Air Force Plant PJKS, Systems Integration Laboratory, Systems Integration Laboratory Building, Waterton Canyon Road & Colorado Highway 121, Lakewood, Jefferson County, CO

  18. 48 CFR 252.209-7007 - Prohibited Financial Interests for Lead System Integrators.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Interests for Lead System Integrators. 252.209-7007 Section 252.209-7007 Federal Acquisition Regulations... for Lead System Integrators. As prescribed in 209.570-4(b), use the following clause: Prohibited Financial Interests for Lead System Integrators (JUL 2009) (a) Definitions. As used in this clause— (1) Lead...

  19. 48 CFR 3052.209-75 - Prohibited financial interests for lead system integrators.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... interests for lead system integrators. 3052.209-75 Section 3052.209-75 Federal Acquisition Regulations... interests for lead system integrators. As prescribed in (HSAR) 48 CFR 3009.570-4(b), use the following clause: Prohibited Financial Interests for Lead System Integrators (JUL 2010) (a) Definitions. As used in...

  20. 48 CFR 252.209-7007 - Prohibited Financial Interests for Lead System Integrators.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Interests for Lead System Integrators. 252.209-7007 Section 252.209-7007 Federal Acquisition Regulations... for Lead System Integrators. As prescribed in 209.570-4(b), use the following clause: Prohibited Financial Interests for Lead System Integrators (JUL 2009) (a) Definitions. As used in this clause— (1) Lead...

  1. 48 CFR 3052.209-75 - Prohibited financial interests for lead system integrators.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... interests for lead system integrators. 3052.209-75 Section 3052.209-75 Federal Acquisition Regulations... interests for lead system integrators. As prescribed in (HSAR) 48 CFR 3009.570-4(b), use the following clause: Prohibited Financial Interests for Lead System Integrators (JUL 2010) (a) Definitions. As used in...

  2. 48 CFR 252.209-7007 - Prohibited Financial Interests for Lead System Integrators.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Interests for Lead System Integrators. 252.209-7007 Section 252.209-7007 Federal Acquisition Regulations... for Lead System Integrators. As prescribed in 209.570-4(b), use the following clause: Prohibited Financial Interests for Lead System Integrators (JUL 2009) (a) Definitions. As used in this clause— (1) Lead...

  3. 48 CFR 3052.209-75 - Prohibited financial interests for lead system integrators.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... interests for lead system integrators. 3052.209-75 Section 3052.209-75 Federal Acquisition Regulations... interests for lead system integrators. As prescribed in (HSAR) 48 CFR 3009.570-4(b), use the following clause: PROHIBITED FINANCIAL INTERESTS FOR LEAD SYSTEM INTEGRATORS (JUL 2010) (a) Definitions. As used in...

  4. 48 CFR 252.209-7007 - Prohibited Financial Interests for Lead System Integrators.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Interests for Lead System Integrators. 252.209-7007 Section 252.209-7007 Federal Acquisition Regulations... for Lead System Integrators. As prescribed in 209.570-4(b), use the following clause: Prohibited Financial Interests for Lead System Integrators (JUL 2009) (a) Definitions. As used in this clause— (1) Lead...

  5. 48 CFR 3052.209-75 - Prohibited financial interests for lead system integrators.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... interests for lead system integrators. 3052.209-75 Section 3052.209-75 Federal Acquisition Regulations... interests for lead system integrators. As prescribed in (HSAR) 48 CFR 3009.570-4(b), use the following clause: Prohibited Financial Interests for Lead System Integrators (JUL 2010) (a) Definitions. As used in...

  6. Process and information integration via hypermedia

    NASA Technical Reports Server (NTRS)

    Hammen, David G.; Labasse, Daniel L.; Myers, Robert M.

    1990-01-01

    Success stories for advanced automation prototypes abound in the literature but the deployments of practical large systems are few in number. There are several factors that militate against the maturation of such prototypes into products. Here, the integration of advanced automation software into large systems is discussed. Advanced automation systems tend to be specific applications that need to be integrated and aggregated into larger systems. Systems integration can be achieved by providing expert user-developers with verified tools to efficiently create small systems that interface to large systems through standard interfaces. The use of hypermedia as such a tool in the context of the ground control centers that support Shuttle and space station operations is explored. Hypermedia can be an integrating platform for data, conventional software, and advanced automation software, enabling data integration through the display of diverse types of information and through the creation of associative links between chunks of information. Further, hypermedia enables process integration through graphical invoking of system functions. Through analysis and examples, researchers illustrate how diverse information and processing paradigms can be integrated into a single software platform.

  7. The MIST /MIUS Integration and Subsystems Test/ laboratory - A testbed for the MIUS /Modular Integrated Utility System/ program

    NASA Technical Reports Server (NTRS)

    Beckham, W. S., Jr.; Keune, F. A.

    1974-01-01

    The MIUS (Modular Integrated Utility System) concept is to be an energy-conserving, economically feasible, integrated community utility system to provide five necessary services: electricity generation, space heating and air conditioning, solid waste processing, liquid waste processing, and residential water purification. The MIST (MIUS Integration and Subsystem Test) integrated system testbed constructed at the Johnson Space Center in Houston includes subsystems for power generation, heating, ventilation, and air conditioning (HVAC), wastewater management, solid waste management, and control and monitoring. The key design issues under study include thermal integration and distribution techniques, thermal storage, integration of subsystems controls and displays, incinerator performance, effluent characteristics, and odor control.

  8. [Development method of healthcare information system integration based on business collaboration model].

    PubMed

    Li, Shasha; Nie, Hongchao; Lu, Xudong; Duan, Huilong

    2015-02-01

    Integration of heterogeneous systems is the key to hospital information construction due to complexity of the healthcare environment. Currently, during the process of healthcare information system integration, people participating in integration project usually communicate by free-format document, which impairs the efficiency and adaptability of integration. A method utilizing business process model and notation (BPMN) to model integration requirement and automatically transforming it to executable integration configuration was proposed in this paper. Based on the method, a tool was developed to model integration requirement and transform it to integration configuration. In addition, an integration case in radiology scenario was used to verify the method.

  9. Response of MDOF strongly nonlinear systems to fractional Gaussian noises.

    PubMed

    Deng, Mao-Lin; Zhu, Wei-Qiu

    2016-08-01

    In the present paper, multi-degree-of-freedom strongly nonlinear systems are modeled as quasi-Hamiltonian systems and the stochastic averaging method for quasi-Hamiltonian systems (including quasi-non-integrable, completely integrable and non-resonant, completely integrable and resonant, partially integrable and non-resonant, and partially integrable and resonant Hamiltonian systems) driven by fractional Gaussian noise is introduced. The averaged fractional stochastic differential equations (SDEs) are derived. The simulation results for some examples show that the averaged SDEs can be used to predict the response of the original systems and the simulation time for the averaged SDEs is less than that for the original systems.

  10. Response of MDOF strongly nonlinear systems to fractional Gaussian noises

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Deng, Mao-Lin; Zhu, Wei-Qiu, E-mail: wqzhu@zju.edu.cn

    2016-08-15

    In the present paper, multi-degree-of-freedom strongly nonlinear systems are modeled as quasi-Hamiltonian systems and the stochastic averaging method for quasi-Hamiltonian systems (including quasi-non-integrable, completely integrable and non-resonant, completely integrable and resonant, partially integrable and non-resonant, and partially integrable and resonant Hamiltonian systems) driven by fractional Gaussian noise is introduced. The averaged fractional stochastic differential equations (SDEs) are derived. The simulation results for some examples show that the averaged SDEs can be used to predict the response of the original systems and the simulation time for the averaged SDEs is less than that for the original systems.

  11. Information Security Management - Part Of The Integrated Management System

    NASA Astrophysics Data System (ADS)

    Manea, Constantin Adrian

    2015-07-01

    The international management standards allow their integrated approach, thereby combining aspects of particular importance to the activity of any organization, from the quality management systems or the environmental management of the information security systems or the business continuity management systems. Although there is no national or international regulation, nor a defined standard for the Integrated Management System, the need to implement an integrated system occurs within the organization, which feels the opportunity to integrate the management components into a cohesive system, in agreement with the purpose and mission publicly stated. The issues relating to information security in the organization, from the perspective of the management system, raise serious questions to any organization in the current context of electronic information, reason for which we consider not only appropriate but necessary to promote and implement an Integrated Management System Quality - Environment - Health and Operational Security - Information Security

  12. The architecture of enterprise hospital information system.

    PubMed

    Lu, Xudong; Duan, Huilong; Li, Haomin; Zhao, Chenhui; An, Jiye

    2005-01-01

    Because of the complexity of the hospital environment, there exist a lot of medical information systems from different vendors with incompatible structures. In order to establish an enterprise hospital information system, the integration among these heterogeneous systems must be considered. Complete integration should cover three aspects: data integration, function integration and workflow integration. However most of the previous design of architecture did not accomplish such a complete integration. This article offers an architecture design of the enterprise hospital information system based on the concept of digital neural network system in hospital. It covers all three aspects of integration, and eventually achieves the target of one virtual data center with Enterprise Viewer for users of different roles. The initial implementation of the architecture in the 5-year Digital Hospital Project in Huzhou Central hospital of Zhejiang Province is also described.

  13. Multi-viewer tracking integral imaging system and its viewing zone analysis.

    PubMed

    Park, Gilbae; Jung, Jae-Hyun; Hong, Keehoon; Kim, Yunhee; Kim, Young-Hoon; Min, Sung-Wook; Lee, Byoungho

    2009-09-28

    We propose a multi-viewer tracking integral imaging system for viewing angle and viewing zone improvement. In the tracking integral imaging system, the pickup angles in each elemental lens in the lens array are decided by the positions of viewers, which means the elemental image can be made for each viewer to provide wider viewing angle and larger viewing zone. Our tracking integral imaging system is implemented with an infrared camera and infrared light emitting diodes which can track the viewers' exact positions robustly. For multiple viewers to watch integrated three-dimensional images in the tracking integral imaging system, it is needed to formulate the relationship between the multiple viewers' positions and the elemental images. We analyzed the relationship and the conditions for the multiple viewers, and verified them by the implementation of two-viewer tracking integral imaging system.

  14. Analysis of a Real-Time Separation Assurance System with Integrated Time-in-Trail Spacing

    NASA Technical Reports Server (NTRS)

    Aweiss, Arwa S.; Farrahi, Amir H.; Lauderdale, Todd A.; Thipphavong, Adam S.; Lee, Chu H.

    2010-01-01

    This paper describes the implementation and analysis of an integrated ground-based separation assurance and time-based metering prototype system into the Center-TRACON Automation System. The integration of this new capability accommodates constraints in four-dimensions: position (x-y), altitude, and meter-fix crossing time. Experiments were conducted to evaluate the performance of the integrated system and its ability to handle traffic levels up to twice that of today. Results suggest that the integrated system reduces the number and magnitude of time-in-trail spacing violations. This benefit was achieved without adversely affecting the resolution success rate of the system. Also, the data suggest that the integrated system is relatively insensitive to an increase in traffic of twice the current levels.

  15. 48 CFR 3009.570 - Limitations on contractors acting as lead system integrators.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 7 2011-10-01 2011-10-01 false Limitations on contractors acting as lead system integrators. 3009.570 Section 3009.570 Federal Acquisition Regulations System... contractors acting as lead system integrators. ...

  16. On the integrability of some generalized Lotka-Volterra systems

    NASA Astrophysics Data System (ADS)

    Bier, M.; Hijmans, J.; Bountis, T. C.

    1983-08-01

    Several integrable systems of nonlinear ordinary differential equations of the Lotka-Volterra type are identified by the Painleveproperty and completely integrated. One such integrable case of N first order ode's is found, with N-2 free parameters and N arbitrary. The concept of integrability of a general dynamical system, not necessarily derived from a Hamiltonian, is also discussed.

  17. Space station integrated propulsion and fluid systems study. Space station program fluid management systems databook

    NASA Technical Reports Server (NTRS)

    Bicknell, B.; Wilson, S.; Dennis, M.; Lydon, M.

    1988-01-01

    Commonality and integration of propulsion and fluid systems associated with the Space Station elements are being evaluated. The Space Station elements consist of the core station, which includes habitation and laboratory modules, nodes, airlocks, and trusswork; and associated vehicles, platforms, experiments, and payloads. The program is being performed as two discrete tasks. Task 1 investigated the components of the Space Station architecture to determine the feasibility and practicality of commonality and integration among the various propulsion elements. This task was completed. Task 2 is examining integration and commonality among fluid systems which were identified by the Phase B Space Station contractors as being part of the initial operating capability (IOC) and growth Space Station architectures. Requirements and descriptions for reference fluid systems were compiled from Space Station documentation and other sources. The fluid systems being examined are: an experiment gas supply system, an oxygen/hydrogen supply system, an integrated water system, the integrated nitrogen system, and the integrated waste fluids system. Definitions and descriptions of alternate systems were developed, along with analyses and discussions of their benefits and detriments. This databook includes fluid systems descriptions, requirements, schematic diagrams, component lists, and discussions of the fluid systems. In addition, cost comparison are used in some cases to determine the optimum system for a specific task.

  18. A study of compositional verification based IMA integration method

    NASA Astrophysics Data System (ADS)

    Huang, Hui; Zhang, Guoquan; Xu, Wanmeng

    2018-03-01

    The rapid development of avionics systems is driving the application of integrated modular avionics (IMA) systems. But meanwhile it is improving avionics system integration, complexity of system test. Then we need simplify the method of IMA system test. The IMA system supports a module platform that runs multiple applications, and shares processing resources. Compared with federated avionics system, IMA system is difficult to isolate failure. Therefore, IMA system verification will face the critical problem is how to test shared resources of multiple application. For a simple avionics system, traditional test methods are easily realizing to test a whole system. But for a complex system, it is hard completed to totally test a huge and integrated avionics system. Then this paper provides using compositional-verification theory in IMA system test, so that reducing processes of test and improving efficiency, consequently economizing costs of IMA system integration.

  19. Integrating an object system into CLIPS: Language design and implementation issues

    NASA Technical Reports Server (NTRS)

    Auburn, Mark

    1990-01-01

    This paper describes the reasons why an object system with integrated pattern-matching and object-oriented programming facilities is desirable for CLIPS and how it is possible to integrate such a system into CLIPS while maintaining the run-time performance and the low memory usage for which CLIPS is known. The requirements for an object system in CLIPS that includes object-oriented programming and integrated pattern-matching are discussed and various techniques for optimizing the object system and its integration with the pattern-matcher are presented.

  20. Decentralized Multisensory Information Integration in Neural Systems.

    PubMed

    Zhang, Wen-Hao; Chen, Aihua; Rasch, Malte J; Wu, Si

    2016-01-13

    How multiple sensory cues are integrated in neural circuitry remains a challenge. The common hypothesis is that information integration might be accomplished in a dedicated multisensory integration area receiving feedforward inputs from the modalities. However, recent experimental evidence suggests that it is not a single multisensory brain area, but rather many multisensory brain areas that are simultaneously involved in the integration of information. Why many mutually connected areas should be needed for information integration is puzzling. Here, we investigated theoretically how information integration could be achieved in a distributed fashion within a network of interconnected multisensory areas. Using biologically realistic neural network models, we developed a decentralized information integration system that comprises multiple interconnected integration areas. Studying an example of combining visual and vestibular cues to infer heading direction, we show that such a decentralized system is in good agreement with anatomical evidence and experimental observations. In particular, we show that this decentralized system can integrate information optimally. The decentralized system predicts that optimally integrated information should emerge locally from the dynamics of the communication between brain areas and sheds new light on the interpretation of the connectivity between multisensory brain areas. To extract information reliably from ambiguous environments, the brain integrates multiple sensory cues, which provide different aspects of information about the same entity of interest. Here, we propose a decentralized architecture for multisensory integration. In such a system, no processor is in the center of the network topology and information integration is achieved in a distributed manner through reciprocally connected local processors. Through studying the inference of heading direction with visual and vestibular cues, we show that the decentralized system can integrate information optimally, with the reciprocal connections between processers determining the extent of cue integration. Our model reproduces known multisensory integration behaviors observed in experiments and sheds new light on our understanding of how information is integrated in the brain. Copyright © 2016 Zhang et al.

  1. Decentralized Multisensory Information Integration in Neural Systems

    PubMed Central

    Zhang, Wen-hao; Chen, Aihua

    2016-01-01

    How multiple sensory cues are integrated in neural circuitry remains a challenge. The common hypothesis is that information integration might be accomplished in a dedicated multisensory integration area receiving feedforward inputs from the modalities. However, recent experimental evidence suggests that it is not a single multisensory brain area, but rather many multisensory brain areas that are simultaneously involved in the integration of information. Why many mutually connected areas should be needed for information integration is puzzling. Here, we investigated theoretically how information integration could be achieved in a distributed fashion within a network of interconnected multisensory areas. Using biologically realistic neural network models, we developed a decentralized information integration system that comprises multiple interconnected integration areas. Studying an example of combining visual and vestibular cues to infer heading direction, we show that such a decentralized system is in good agreement with anatomical evidence and experimental observations. In particular, we show that this decentralized system can integrate information optimally. The decentralized system predicts that optimally integrated information should emerge locally from the dynamics of the communication between brain areas and sheds new light on the interpretation of the connectivity between multisensory brain areas. SIGNIFICANCE STATEMENT To extract information reliably from ambiguous environments, the brain integrates multiple sensory cues, which provide different aspects of information about the same entity of interest. Here, we propose a decentralized architecture for multisensory integration. In such a system, no processor is in the center of the network topology and information integration is achieved in a distributed manner through reciprocally connected local processors. Through studying the inference of heading direction with visual and vestibular cues, we show that the decentralized system can integrate information optimally, with the reciprocal connections between processers determining the extent of cue integration. Our model reproduces known multisensory integration behaviors observed in experiments and sheds new light on our understanding of how information is integrated in the brain. PMID:26758843

  2. Development and validation of the crew-station system-integration research facility

    NASA Technical Reports Server (NTRS)

    Nedell, B.; Hardy, G.; Lichtenstein, T.; Leong, G.; Thompson, D.

    1986-01-01

    The various issues associated with the use of integrated flight management systems in aircraft were discussed. To address these issues a fixed base integrated flight research (IFR) simulation of a helicopter was developed to support experiments that contribute to the understanding of design criteria for rotorcraft cockpits incorporating advanced integrated flight management systems. A validation experiment was conducted that demonstrates the main features of the facility and the capability to conduct crew/system integration research.

  3. Contact Hamiltonian systems and complete integrability

    NASA Astrophysics Data System (ADS)

    Visinescu, Mihai

    2017-12-01

    We summarize recent results on the integrability of Hamiltonian systems on contact manifolds. We explain how to extend the classical formulation of action-angle variables to contact integrable systems. Using the Jacobi brackets defined on contact manifolds, we discuss the commutativity of first integrals for contact Hamiltonian systems and present the construction of generalized contact action-angle variables. We illustrate the integrability in the contact geometry on the five-dimensional Sasaki-Einstein spaces T1,1 and Yp,q.

  4. Measuring primary care practice performance within an integrated delivery system: a case study.

    PubMed

    Stewart, Louis J; Greisler, David

    2002-01-01

    This article examines the use of an integrated performance measurement system to plan and control primary care service delivery within an integrated delivery system. We review a growing body of literature that focuses on the development and implementation of management reporting systems among healthcare providers. Our study extends the existing literature by examining the use of performance information generated by an integrated performance measurement system within a healthcare organization. We conduct our examination through a case study of the WMG Primary Care Medicine Group, the primary care medical group practice of WellSpan Health System. WellSpan Health System is an integrated delivery system that serves south central Pennsylvania and northern Maryland. Our study examines the linkage between WellSpan Health's strategic objectives and its primary care medicine group's integrated performance measurement system. The conceptual design of this integrated performance measurement system combines financial metrics with practice management and clinical operating metrics to provide a more complete picture of medical group performance. Our findings demonstrate that WellSpan Health was able to achieve superior financial results despite a weak linkage between its integrated performance measurement system and its strategic objectives. WellSpan Health achieved this objective for its primary care medicine group by linking clinical performance information to physician compensation and reporting practice management performance through the use of statistical process charts. They found that the combined mechanisms of integrated performance measurement and statistical process control charts improved organizational learning and communications between organizational stakeholders.

  5. Human-Systems Integration (HSI) and the Network Integration Evaluations (NIEs), Part 3: Mitigating Cognitive Load in Network-Enabled Mission Command

    DTIC Science & Technology

    2016-06-01

    ARL-TR-7698 ● JUNE 2016 US Army Research Laboratory Human -Systems Integration (HSI) and the Network Integration Evaluations...ARL-TR-7698 ● JUNE 2016 US Army Research Laboratory Human -Systems Integration (HSI) and the Network Integration Evaluations (NIEs), Part 3...Mitigating Cognitive Load in Network-Enabled Mission Command by John K Hawley Human Research and Engineering Directorate, ARL Michael W

  6. Investigation on navigation patterns of inertial/celestial integrated systems

    NASA Astrophysics Data System (ADS)

    Luo, Dacheng; Liu, Yan; Liu, Zhiguo; Jiao, Wei; Wang, Qiuyan

    2014-11-01

    It is known that Strapdown Inertial Navigation System (SINS), Global Navigation Satellite System (GNSS) and Celestial Navigation System (CNS) can complement each other's advantages. The SINS/CNS integrated system, which has the characteristics of strong autonomy, high accuracy and good anti-jamming, is widely used in military and civilian applications. Similar to SINS/GNSS integrated system, the SINS/CNS integrated system can also be divided into three kinds according to the difference of integrating depth, i.e., loosely coupled pattern, tightly coupled pattern and deeply coupled pattern. In this paper, the principle and characteristics of each pattern of SINS/CNS system are analyzed. Based on the comparison of these patterns, a novel deeply coupled SINS/CNS integrated navigation scheme is proposed. The innovation of this scheme is that a new star pattern matching method aided by SINS information is put forward. Thus the complementary features of these two subsystems are reflected.

  7. Automatic detection, tracking and sensor integration

    NASA Astrophysics Data System (ADS)

    Trunk, G. V.

    1988-06-01

    This report surveys the state of the art of automatic detection, tracking, and sensor integration. In the area of detection, various noncoherent integrators such as the moving window integrator, feedback integrator, two-pole filter, binary integrator, and batch processor are discussed. Next, the three techniques for controlling false alarms, adapting thresholds, nonparametric detectors, and clutter maps are presented. In the area of tracking, a general outline is given of a track-while-scan system, and then a discussion is presented of the file system, contact-entry logic, coordinate systems, tracking filters, maneuver-following logic, tracking initiating, track-drop logic, and correlation procedures. Finally, in the area of multisensor integration the problems of colocated-radar integration, multisite-radar integration, radar-IFF integration, and radar-DF bearing strobe integration are treated.

  8. Suit study - The impact of VMS in subsystem integration

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hill, B.; Watts, R.

    1992-02-01

    One of the thrusts of the Wright Laboratory/FIVE-sponsored Subsystem Integration Technology (SUIT) study is to investigate the impact of emerging vehicle management system (VMS) concepts on subsystem integration. This paper summarizes the issues relating to VMS/subsystem integration as examined during the Northrop SUIT study. Projected future weapon system requirements are identified and their impact on VMS and subsystem design interpreted. Integrated VMS/subsystem control and management functions are proposed. A candidate system VMS architecture satisfying the aforementioned weapon system requirements and providing the identified control and management functions is proposed. This architecture is used, together with the environmental control system, asmore » an illustrative subsystem example, to address the risks associated with the design, development, procurement, integration and testing of integrated VMS/subsystem concepts. The conclusion is that the development process requires an airframer to adopt the role of subsystem integrator, the consequences of which are discussed. 2 refs.« less

  9. Guest editorial. Integrated healthcare information systems.

    PubMed

    Li, Ling; Ge, Ri-Li; Zhou, Shang-Ming; Valerdi, Ricardo

    2012-07-01

    The use of integrated information systems for healthcare has been started more than a decade ago. In recent years, rapid advances in information integration methods have spurred tremendous growth in the use of integrated information systems in healthcare delivery. Various techniques have been used for probing such integrated systems. These techniques include service-oriented architecture (SOA), EAI, workflow management, grid computing, and others. Many applications require a combination of these techniques, which gives rise to the emergence of enterprise systems in healthcare. Development of the techniques originated from different disciplines has the potential to significantly improve the performance of enterprise systems in healthcare. This editorial paper briefly introduces the enterprise systems in the perspective of healthcare informatics.

  10. U.S. Space Shuttle GPS navigation capability for all mission phases

    NASA Technical Reports Server (NTRS)

    Kachmar, Peter; Chu, William; Montez, Moises

    1993-01-01

    Incorporating a GPS capability on the Space Shuttle presented unique system integration design considerations and has led to an integration concept that has minimum impact on the existing Shuttle hardware and software systems. This paper presents the Space Shuttle GPS integrated design and the concepts used in implementing this GPS capability. The major focus of the paper is on the modifications that will be made to the navigation systems in the Space Shuttle General Purpose Computers (GPC) and on the Operational Requirements of the integrated GPS/GPC system. Shuttle navigation system architecture, functions and operations are discussed for the current system and with the GPS integrated navigation capability. The GPS system integration design presented in this paper has been formally submitted to the Shuttle Avionics Software Control Board for implementation in the on-board GPC software.

  11. A Survey of Applications and Research in Integrated Design Systems Technology

    NASA Technical Reports Server (NTRS)

    1998-01-01

    The initial part of the study was begun with a combination of literature searches, World Wide Web searches, and contacts with individuals and companies who were known to members of our team to have an interest in topics that seemed to be related to our study. There is a long list of such topics, such as concurrent engineering, design for manufacture, life-cycle engineering, systems engineering, systems integration, systems design, design systems, integrated product and process approaches, enterprise integration, integrated product realization, and similar terms. These all capture, at least in part, the flavor of what we describe here as integrated design systems. An inhibiting factor in this inquiry was the absence of agreed terminology for the study of integrated design systems. It is common for the term to be applied to what are essentially augmented Computer-Aided Design (CAD) systems, which are integrated only to the extent that agreements have been reached to attach proprietary extensions to proprietary CAD programs. It is also common for some to use the term integrated design systems to mean a system that applies only, or mainly, to the design phase of a product life cycle. It is likewise common for many of the terms listed earlier to be used as synonyms for integrated design systems. We tried to avoid this ambiguity by adopting the definition of integrated design systems that is implied in the introductory notes that we provided to our contacts, cited earlier. We thus arrived at this definition: Integrated Design Systems refers to the integration of the different tools and processes that comprise the engineering, of complex systems. It takes a broad view of the engineering of systems, to include consideration of the entire product realization process and the product life cycle. An important aspect of integrated design systems is the extent to which they integrate existing, "islands of automation" into a comprehensive design and product realization environment. As the study progressed, we relied increasingly upon a networking approach to lead us to new information. The departure point for such searches often was a government-sponsored project or a company initiative. The advantage of this approach was that short conversations with knowledgeable persons would usually cut through confusion over differences of terminology, thereby somewhat reducing the search space of the study. Even so, it was not until late in our eight-month inquiry that we began to see signs of convergence of the search, in the sense that a number of the latest inquiries began to turn up references to earlier contacts. As suggested above, this convergence often occurred with respect to particular government or company projects.

  12. CONFIG: Integrated engineering of systems and their operation

    NASA Technical Reports Server (NTRS)

    Malin, Jane T.; Ryan, Dan; Fleming, Land

    1994-01-01

    This article discusses CONFIG 3, a prototype software tool that supports integrated conceptual design evaluation from early in the product life cycle, by supporting isolated or integrated modeling, simulation, and analysis of the function, structure, behavior, failures and operations of system designs. Integration and reuse of models is supported in an object-oriented environment providing capabilities for graph analysis and discrete event simulation. CONFIG supports integration among diverse modeling approaches (component view, configuration or flow path view, and procedure view) and diverse simulation and analysis approaches. CONFIG is designed to support integrated engineering in diverse design domains, including mechanical and electro-mechanical systems, distributed computer systems, and chemical processing and transport systems.

  13. Air Force Integrated Personnel and Pay System (AFIPPS)

    DTIC Science & Technology

    2016-03-01

    2016 Major Automated Information System Annual Report Air Force Integrated Personnel and Pay System (AFIPPS) Defense Acquisition Management...DSN Fax: 665-1207 Date Assigned: February 1, 2016 Program Information Program Name Air Force Integrated Personnel and Pay System (AFIPPS) DoD...therefore, no Original Estimate has been established. AFIPPS 2016 MAR UNCLASSIFIED 4 Program Description Air Force Integrated Personnel and Pay

  14. Integration of Schemas on the Pre-Design Level Using the KCPM-Approach

    NASA Astrophysics Data System (ADS)

    Vöhringer, Jürgen; Mayr, Heinrich C.

    Integration is a central research and operational issue in information system design and development. It can be conducted on the system, schema, and view or data level. On the system level, integration deals with the progressive linking and testing of system components to merge their functional and technical characteristics and behavior into a comprehensive, interoperable system. Schema integration comprises the comparison and merging of two or more schemas, usually conceptual database schemas. The integration of data deals with merging the contents of multiple sources of related data. View integration is similar to schema integration, however focuses on views and queries on these instead of schemas. All these types of integration have in common, that two or more sources are merged and previously compared, in order to identify matches and mismatches as well as conflicts and inconsistencies. The sources may stem from heterogeneous companies, organizational units or projects. Integration enables the reuse and combined use of source components.

  15. Grid Facilities | Grid Modernization | NREL

    Science.gov Websites

    groundbreaking innovations and collaboration in grid research. Photo of the Energy Systems Integration Facility Energy Systems Integration Facility The Energy Systems Integration Facility is the nation's premier user Located in Boulder, Colorado, the National Wind Technology Center (NWTC) offers similar integration

  16. Multi-agent based control of large-scale complex systems employing distributed dynamic inference engine

    NASA Astrophysics Data System (ADS)

    Zhang, Daili

    Increasing societal demand for automation has led to considerable efforts to control large-scale complex systems, especially in the area of autonomous intelligent control methods. The control system of a large-scale complex system needs to satisfy four system level requirements: robustness, flexibility, reusability, and scalability. Corresponding to the four system level requirements, there arise four major challenges. First, it is difficult to get accurate and complete information. Second, the system may be physically highly distributed. Third, the system evolves very quickly. Fourth, emergent global behaviors of the system can be caused by small disturbances at the component level. The Multi-Agent Based Control (MABC) method as an implementation of distributed intelligent control has been the focus of research since the 1970s, in an effort to solve the above-mentioned problems in controlling large-scale complex systems. However, to the author's best knowledge, all MABC systems for large-scale complex systems with significant uncertainties are problem-specific and thus difficult to extend to other domains or larger systems. This situation is partly due to the control architecture of multiple agents being determined by agent to agent coupling and interaction mechanisms. Therefore, the research objective of this dissertation is to develop a comprehensive, generalized framework for the control system design of general large-scale complex systems with significant uncertainties, with the focus on distributed control architecture design and distributed inference engine design. A Hybrid Multi-Agent Based Control (HyMABC) architecture is proposed by combining hierarchical control architecture and module control architecture with logical replication rings. First, it decomposes a complex system hierarchically; second, it combines the components in the same level as a module, and then designs common interfaces for all of the components in the same module; third, replications are made for critical agents and are organized into logical rings. This architecture maintains clear guidelines for complexity decomposition and also increases the robustness of the whole system. Multiple Sectioned Dynamic Bayesian Networks (MSDBNs) as a distributed dynamic probabilistic inference engine, can be embedded into the control architecture to handle uncertainties of general large-scale complex systems. MSDBNs decomposes a large knowledge-based system into many agents. Each agent holds its partial perspective of a large problem domain by representing its knowledge as a Dynamic Bayesian Network (DBN). Each agent accesses local evidence from its corresponding local sensors and communicates with other agents through finite message passing. If the distributed agents can be organized into a tree structure, satisfying the running intersection property and d-sep set requirements, globally consistent inferences are achievable in a distributed way. By using different frequencies for local DBN agent belief updating and global system belief updating, it balances the communication cost with the global consistency of inferences. In this dissertation, a fully factorized Boyen-Koller (BK) approximation algorithm is used for local DBN agent belief updating, and the static Junction Forest Linkage Tree (JFLT) algorithm is used for global system belief updating. MSDBNs assume a static structure and a stable communication network for the whole system. However, for a real system, sub-Bayesian networks as nodes could be lost, and the communication network could be shut down due to partial damage in the system. Therefore, on-line and automatic MSDBNs structure formation is necessary for making robust state estimations and increasing survivability of the whole system. A Distributed Spanning Tree Optimization (DSTO) algorithm, a Distributed D-Sep Set Satisfaction (DDSSS) algorithm, and a Distributed Running Intersection Satisfaction (DRIS) algorithm are proposed in this dissertation. Combining these three distributed algorithms and a Distributed Belief Propagation (DBP) algorithm in MSDBNs makes state estimations robust to partial damage in the whole system. Combining the distributed control architecture design and the distributed inference engine design leads to a process of control system design for a general large-scale complex system. As applications of the proposed methodology, the control system design of a simplified ship chilled water system and a notional ship chilled water system have been demonstrated step by step. Simulation results not only show that the proposed methodology gives a clear guideline for control system design for general large-scale complex systems with dynamic and uncertain environment, but also indicate that the combination of MSDBNs and HyMABC can provide excellent performance for controlling general large-scale complex systems.

  17. Energy Systems Integration: Demonstrating Distribution Feeder Voltage Control

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    2017-01-01

    Overview fact sheet about the Smarter Grid Solutions Integrated Network Testbed for Energy Grid Research and Technology Experimentation (INTEGRATE) project at the Energy Systems Integration Facility. INTEGRATE is part of the U.S. Department of Energy's Grid Modernization Initiative.

  18. Energy Systems Integration: Demonstrating Distributed Grid-Edge Control Hierarchy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    2017-01-01

    Overview fact sheet about the OMNETRIC Group Integrated Network Testbed for Energy Grid Research and Technology Experimentation (INTEGRATE) project at the Energy Systems Integration Facility. INTEGRATE is part of the U.S. Department of Energy's Grid Modernization Initiative.

  19. 75 FR 53262 - Privacy Act of 1974; System of Records

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-31

    ... a new Privacy Act system of records, JUSTICE/FBI- 021, the Data Integration and Visualization System... Act system of records, the Data Integration and Visualization System (DIVS), Justice/FBI-021. The... investigative mission by enabling access, search, integration, and analytics across multiple existing databases...

  20. V-band integrated quadriphase modulator

    NASA Technical Reports Server (NTRS)

    Grote, A.; Chang, K.

    1983-01-01

    A V-band integrated circuit quadriphase shift keyed modulator/exciter for space communications systems was developed. Intersatellite communications systems require direct modulation at 60 GHz to enhance signal processing capability. For most systems, particularly space applications, small and lightweight components are essential to alleviate severe system design constraints. Thus to achieve wideband, high data rate systems, direct modulation techniques at millimeter waves using solid state integrated circuit technology are an integral part of the overall technology developments.

  1. MEMS Technology for Space Applications

    NASA Technical Reports Server (NTRS)

    vandenBerg, A.; Spiering, V. L.; Lammerink, T. S. J.; Elwenspoek, M.; Bergveld, P.

    1995-01-01

    Micro-technology enables the manufacturing of all kinds of components for miniature systems or micro-systems, such as sensors, pumps, valves, and channels. The integration of these components into a micro-electro-mechanical system (MEMS) drastically decreases the total system volume and mass. These properties, combined with the increasing need for monitoring and control of small flows in (bio)chemical experiments, makes MEMS attractive for space applications. The level of integration and applied technology depends on the product demands and the market. The ultimate integration is process integration, which results in a one-chip system. An example of process integration is a dosing system of pump, flow sensor, micromixer, and hybrid feedback electronics to regulate the flow. However, for many applications, a hybrid integration of components is sufficient and offers the advantages of design flexibility and even the exchange of components in the case of a modular set up. Currently, we are working on hybrid integration of all kinds of sensors (physical and chemical) and flow system modules towards a modular system; the micro total analysis system (micro TAS). The substrate contains electrical connections as in a printed circuit board (PCB) as well as fluid channels for a circuit channel board (CCB) which, when integrated, form a mixed circuit board (MCB).

  2. Grid Integration Studies: Advancing Clean Energy Planning and Deployment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Katz, Jessica; Chernyakhovskiy, Ilya

    2016-07-01

    Integrating significant variable renewable energy (VRE) into the grid requires an evolution in power system planning and operation. To plan for this evolution, power system stakeholders can undertake grid integration studies. This Greening the Grid document reviews grid integration studies, common elements, questions, and guidance for system planners.

  3. 76 FR 69284 - Certain Integrated Solar Power Systems and Components Thereof: Notice of Institution of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-08

    ... the United States after importation of certain integrated solar power systems and components thereof... certain integrated solar power systems and components thereof that infringe one or more of claims 6 and 10... INTERNATIONAL TRADE COMMISSION [Investigation No. 337-TA-811] Certain Integrated Solar Power...

  4. Take a Tour of Our Facility | Energy Systems Integration Facility | NREL

    Science.gov Websites

    Take a Tour of Our Facility Take a Tour of Our Facility The Energy Systems Integration Facility Optical Characterization Laboratory System Performance Laboratory Power Systems Integration Laboratory Control Room Energy Storage Laboratory Outdoor Testing Areas Outdoor Testing Areas Energy Systems

  5. 48 CFR 3007.106-70 - Limitations on Lead System Integrators.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 7 2012-10-01 2012-10-01 false Limitations on Lead System... Acquisition Plans 3007.106-70 Limitations on Lead System Integrators. See (HSAR) 48 CFR 3009.570 for policy applicable to acquisition strategies that consider the use of lead system integrators. ...

  6. 48 CFR 3007.106-70 - Limitations on Lead System Integrators.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 7 2014-10-01 2014-10-01 false Limitations on Lead System... Acquisition Plans 3007.106-70 Limitations on Lead System Integrators. See (HSAR) 48 CFR 3009.570 for policy applicable to acquisition strategies that consider the use of lead system integrators. ...

  7. 48 CFR 3007.106-70 - Limitations on Lead System Integrators.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 7 2011-10-01 2011-10-01 false Limitations on Lead System... Acquisition Plans 3007.106-70 Limitations on Lead System Integrators. See (HSAR) 48 CFR 3009.570 for policy applicable to acquisition strategies that consider the use of lead system integrators. ...

  8. 48 CFR 3007.106-70 - Limitations on Lead System Integrators.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 7 2013-10-01 2012-10-01 true Limitations on Lead System... Acquisition Plans 3007.106-70 Limitations on Lead System Integrators. See (HSAR) 48 CFR 3009.570 for policy applicable to acquisition strategies that consider the use of lead system integrators. ...

  9. 48 CFR 3007.106-70 - Limitations on Lead System Integrators.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Limitations on Lead System... Acquisition Plans 3007.106-70 Limitations on Lead System Integrators. See (HSAR) 48 CFR 3009.570 for policy applicable to acquisition strategies that consider the use of lead system integrators. ...

  10. IEMIS (Integrated Emergency Management Information System) Floodplain Mapping Based on a Lidar Derived Data Set.

    DTIC Science & Technology

    1988-02-05

    0-A193 971 IEMIS (INTEGRATED EMERGENCY MANAGEMENT INFORMATION SYSTEM ) FLOODPLRIN MAP.. (U) ARMY ENGINEER WATERWAYS EXPERIMENT STATION VICKSBURG HS J...illustrate the application of the automated mapping capabilities of the Integrated Emergency Management Information System (IEMIS) to FISs. Unclassified...mapping capabilities of the Integrated Emergency Management Information System (IEMIS) to FISs. II. BACKGROUND The concept of mounting laser ranging

  11. Development of Spreadsheet-Based Integrated Transaction Processing Systems and Financial Reporting Systems

    NASA Astrophysics Data System (ADS)

    Ariana, I. M.; Bagiada, I. M.

    2018-01-01

    Development of spreadsheet-based integrated transaction processing systems and financial reporting systems is intended to optimize the capabilities of spreadsheet in accounting data processing. The purpose of this study are: 1) to describe the spreadsheet-based integrated transaction processing systems and financial reporting systems; 2) to test its technical and operational feasibility. This study type is research and development. The main steps of study are: 1) needs analysis (need assessment); 2) developing spreadsheet-based integrated transaction processing systems and financial reporting systems; and 3) testing the feasibility of spreadsheet-based integrated transaction processing systems and financial reporting systems. The technical feasibility include the ability of hardware and operating systems to respond the application of accounting, simplicity and ease of use. Operational feasibility include the ability of users using accounting applications, the ability of accounting applications to produce information, and control applications of the accounting applications. The instrument used to assess the technical and operational feasibility of the systems is the expert perception questionnaire. The instrument uses 4 Likert scale, from 1 (strongly disagree) to 4 (strongly agree). Data were analyzed using percentage analysis by comparing the number of answers within one (1) item by the number of ideal answer within one (1) item. Spreadsheet-based integrated transaction processing systems and financial reporting systems integrate sales, purchases, and cash transaction processing systems to produce financial reports (statement of profit or loss and other comprehensive income, statement of changes in equity, statement of financial position, and statement of cash flows) and other reports. Spreadsheet-based integrated transaction processing systems and financial reporting systems is feasible from the technical aspects (87.50%) and operational aspects (84.17%).

  12. Integrated Main Propulsion System Performance Reconstruction Process/Models

    NASA Technical Reports Server (NTRS)

    Lopez, Eduardo; Elliott, Katie; Snell, Steven; Evans, Michael

    2013-01-01

    The Integrated Main Propulsion System (MPS) Performance Reconstruction process provides the MPS post-flight data files needed for postflight reporting to the project integration management and key customers to verify flight performance. This process/model was used as the baseline for the currently ongoing Space Launch System (SLS) work. The process utilizes several methodologies, including multiple software programs, to model integrated propulsion system performance through space shuttle ascent. It is used to evaluate integrated propulsion systems, including propellant tanks, feed systems, rocket engine, and pressurization systems performance throughout ascent based on flight pressure and temperature data. The latest revision incorporates new methods based on main engine power balance model updates to model higher mixture ratio operation at lower engine power levels.

  13. Establishment of key grid-connected performance index system for integrated PV-ES system

    NASA Astrophysics Data System (ADS)

    Li, Q.; Yuan, X. D.; Qi, Q.; Liu, H. M.

    2016-08-01

    In order to further promote integrated optimization operation of distributed new energy/ energy storage/ active load, this paper studies the integrated photovoltaic-energy storage (PV-ES) system which is connected with the distribution network, and analyzes typical structure and configuration selection for integrated PV-ES generation system. By combining practical grid- connected characteristics requirements and technology standard specification of photovoltaic generation system, this paper takes full account of energy storage system, and then proposes several new grid-connected performance indexes such as paralleled current sharing characteristic, parallel response consistency, adjusting characteristic, virtual moment of inertia characteristic, on- grid/off-grid switch characteristic, and so on. A comprehensive and feasible grid-connected performance index system is then established to support grid-connected performance testing on integrated PV-ES system.

  14. A SINS/SRS/GNS Autonomous Integrated Navigation System Based on Spectral Redshift Velocity Measurements.

    PubMed

    Wei, Wenhui; Gao, Zhaohui; Gao, Shesheng; Jia, Ke

    2018-04-09

    In order to meet the requirements of autonomy and reliability for the navigation system, combined with the method of measuring speed by using the spectral redshift information of the natural celestial bodies, a new scheme, consisting of Strapdown Inertial Navigation System (SINS)/Spectral Redshift (SRS)/Geomagnetic Navigation System (GNS), is designed for autonomous integrated navigation systems. The principle of this SINS/SRS/GNS autonomous integrated navigation system is explored, and the corresponding mathematical model is established. Furthermore, a robust adaptive central difference particle filtering algorithm is proposed for this autonomous integrated navigation system. The simulation experiments are conducted and the results show that the designed SINS/SRS/GNS autonomous integrated navigation system possesses good autonomy, strong robustness and high reliability, thus providing a new solution for autonomous navigation technology.

  15. The Design and Implementation of an Integrated Financial Control System.

    ERIC Educational Resources Information Center

    Alexander, George D.

    1978-01-01

    The design and implementation of an integrated financial control system at Clemson University are described. The advantages of considering the integration of systems to meet university-wide objectives as design criteria are discussed as well as sub-system relationships. (Author/BH)

  16. Energy Systems Integration: Demonstrating Distributed Resource Communications

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    2017-01-01

    Overview fact sheet about the Electric Power Research Institute (EPRI) and Schneider Electric Integrated Network Testbed for Energy Grid Research and Technology Experimentation (INTEGRATE) project at the Energy Systems Integration Facility. INTEGRATE is part of the U.S. Department of Energy's Grid Modernization Initiative.

  17. Systems Engineering and Integration for Technology Programs

    NASA Technical Reports Server (NTRS)

    Kennedy, Kruss J.

    2006-01-01

    The Architecture, Habitability & Integration group (AH&I) is a system engineering and integration test team within the NASA Crew and Thermal Systems Division (CTSD) at Johnson Space Center. AH&I identifies and resolves system-level integration issues within the research and technology development community. The timely resolution of these integration issues is fundamental to the development of human system requirements and exploration capability. The integration of the many individual components necessary to construct an artificial environment is difficult. The necessary interactions between individual components and systems must be approached in a piece-wise fashion to achieve repeatable results. A formal systems engineering (SE) approach to define, develop, and integrate quality systems within the life support community has been developed. This approach will allow a Research & Technology Program to systematically approach the development, management, and quality of technology deliverables to the various exploration missions. A tiered system engineering structure has been proposed to implement best systems engineering practices across all development levels from basic research to working assemblies. These practices will be implemented through a management plan across all applicable programs, projects, elements and teams. While many of the engineering practices are common to other industries, the implementation is specific to technology development. An accounting of the systems engineering management philosophy will be discussed and the associated programmatic processes will be presented.

  18. The Design of a Practical Enterprise Safety Management System

    NASA Astrophysics Data System (ADS)

    Gabbar, Hossam A.; Suzuki, Kazuhiko

    This book presents design guidelines and implementation approaches for enterprise safety management system as integrated within enterprise integrated systems. It shows new model-based safety management where process design automation is integrated with enterprise business functions and components. It proposes new system engineering approach addressed to new generation chemical industry. It will help both the undergraduate and professional readers to build basic knowledge about issues and problems of designing practical enterprise safety management system, while presenting in clear way, the system and information engineering practices to design enterprise integrated solution.

  19. Crop and cattle production responses to tillage and cover crop management in an integrated crop-livestock system in the southeastern USA

    USDA-ARS?s Scientific Manuscript database

    Integrated crop-livestock systems can help achieve greater environmental quality from disparate crop and livestock systems by recycling nutrients and taking advantage of synergies between systems. We investigated crop and animal production responses in integrated crop-livestock systems with two typ...

  20. 46 CFR 111.50-2 - Systems integration.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Systems integration. 111.50-2 Section 111.50-2 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Overcurrent Protection § 111.50-2 Systems integration. The electrical characteristics of each...

  1. Energy System Basics and Distribution Integration Video Series | Energy

    Science.gov Websites

    renewablesparticularly solar photovoltaic (PV) technologiesonto the distribution grid. Solar Energy Technologies PV Integration Case Studies Integrating Photovoltaic Systems onto Secondary Network Distribution Systems Standards and Codes for U.S. Photovoltaic System Installation Network-Optimal Control of Photovoltaics on

  2. Integrability of systems of two second-order ordinary differential equations admitting four-dimensional Lie algebras

    PubMed Central

    Gazizov, R. K.

    2017-01-01

    We suggest an algorithm for integrating systems of two second-order ordinary differential equations with four symmetries. In particular, if the admitted transformation group has two second-order differential invariants, the corresponding system can be integrated by quadratures using invariant representation and the operator of invariant differentiation. Otherwise, the systems reduce to partially uncoupled forms and can also be integrated by quadratures. PMID:28265184

  3. Integrability of systems of two second-order ordinary differential equations admitting four-dimensional Lie algebras.

    PubMed

    Gainetdinova, A A; Gazizov, R K

    2017-01-01

    We suggest an algorithm for integrating systems of two second-order ordinary differential equations with four symmetries. In particular, if the admitted transformation group has two second-order differential invariants, the corresponding system can be integrated by quadratures using invariant representation and the operator of invariant differentiation. Otherwise, the systems reduce to partially uncoupled forms and can also be integrated by quadratures.

  4. Super-integrable Calogero-type systems admit maximal number of Poisson structures

    NASA Astrophysics Data System (ADS)

    Gonera, C.; Nutku, Y.

    2001-07-01

    We present a general scheme for constructing the Poisson structure of super-integrable dynamical systems of which the rational Calogero-Moser system is the most interesting one. This dynamical system is 2 N-dimensional with 2 N-1 first integrals and our construction yields 2 N-1 degenerate Poisson tensors that each admit 2( N-1) Casimirs. Our results are quite generally applicable to all super-integrable systems and form an alternative to the traditional bi-Hamiltonian approach.

  5. Avionics systems integration technology

    NASA Technical Reports Server (NTRS)

    Stech, George; Williams, James R.

    1988-01-01

    A very dramatic and continuing explosion in digital electronics technology has been taking place in the last decade. The prudent and timely application of this technology will provide Army aviation the capability to prevail against a numerically superior enemy threat. The Army and NASA have exploited this technology explosion in the development and application of avionics systems integration technology for new and future aviation systems. A few selected Army avionics integration technology base efforts are discussed. Also discussed is the Avionics Integration Research Laboratory (AIRLAB) that NASA has established at Langley for research into the integration and validation of avionics systems, and evaluation of advanced technology in a total systems context.

  6. Health Systems Integration of Sexual and Reproductive Health and HIV Services in Sub-Saharan Africa: A Scoping Study

    PubMed Central

    Kendall, Tamil; Langer, Ana; Bärnighausen, Till

    2014-01-01

    Objective: Both sexual and reproductive health (SRH) services and HIV programs in sub-Saharan Africa are typically delivered vertically, operating parallel to national health systems. The objective of this study was to map the evidence on national and international strategies for integration of SRH and HIV services in sub-Saharan Africa and to develop a research agenda for future health systems integration. Methods: We examined the literature on national and international strategies to integrate SRH and HIV services using a scoping study methodology. Current policy frameworks, national HIV strategies and research, and gray literature on integration were mapped. Five countries in sub-Saharan Africa with experience of integrating SRH and HIV services were purposively sampled for detailed thematic analysis, according to the health systems functions of governance, policy and planning, financing, health workforce organization, service organization, and monitoring and evaluation. Results: The major international health policies and donor guidance now support integration. Most integration research has focused on linkages of SRH and HIV front-line services. Yet, the common problems with implementation are related to delayed or incomplete integration of higher level health systems functions: lack of coordinated leadership and unified national integration policies; separate financing streams for SRH and HIV services and inadequate health worker training, supervision and retention. Conclusions: Rigorous health systems research on the integration of SRH and HIV services is urgently needed. Priority research areas include integration impact, performance, and economic evaluation to inform the planning, financing, and coordination of integrated service delivery. PMID:25436826

  7. Ceramic Integration Technologies for Aerospace and Energy Systems: Technical Challenges and Opportunities

    NASA Technical Reports Server (NTRS)

    Singh, Mrityunjay

    2007-01-01

    Ceramic integration technology has been recognized as an enabling technology for the implementation of advanced ceramic systems in a number of high-temperature applications in aerospace, power generation, nuclear, chemical, and electronic industries. Various ceramic integration technologies (joining, brazing, attachments, repair, etc.) play a role in fabrication and manufacturing of large and complex shaped parts of various functionalities. However, the development of robust and reliable integrated systems with optimum performance requires the understanding of many thermochemical and thermomechanical factors, particularly for high temperature applications. In this presentation, various challenges and opportunities in design, fabrication, and testing of integrated similar (ceramic-ceramic) and dissimilar (ceramic-metal) material systems will be discussed. Experimental results for bonding and integration of SiC based LDI fuel injector, high conductivity C/C composite based heat rejection system, solid oxide fuel cells system, ultra high temperature ceramics for leading edges, and ceramic composites for thermostructural applications will be presented. Potential opportunities and need for the development of innovative design philosophies, approaches, and integrated system testing under simulated application conditions will also be discussed.

  8. Nonlinear integrable model of Frenkel-like excitations on a ribbon of triangular lattice

    NASA Astrophysics Data System (ADS)

    Vakhnenko, Oleksiy O.

    2015-03-01

    Following the considerable progress in nanoribbon technology, we propose to model the nonlinear Frenkel-like excitations on a triangular-lattice ribbon by the integrable nonlinear ladder system with the background-controlled intersite resonant coupling. The system of interest arises as a proper reduction of first general semidiscrete integrable system from an infinite hierarchy. The most significant local conservation laws related to the first general integrable system are found explicitly in the framework of generalized recursive approach. The obtained general local densities are equally applicable to any general semidiscrete integrable system from the respective infinite hierarchy. Using the recovered second densities, the Hamiltonian formulation of integrable nonlinear ladder system with background-controlled intersite resonant coupling is presented. In doing so, the relevant Poisson structure turns out to be essentially nontrivial. The Darboux transformation scheme as applied to the first general semidiscrete system is developed and the key role of Bäcklund transformation in justification of its self-consistency is pointed out. The spectral properties of Darboux matrix allow to restore the whole Darboux matrix thus ensuring generation one more soliton as compared with a priori known seed solution of integrable nonlinear system. The power of Darboux-dressing method is explicitly demonstrated in generating the multicomponent one-soliton solution to the integrable nonlinear ladder system with background-controlled intersite resonant coupling.

  9. 75 FR 53342 - Privacy Act of 1974; System of Records

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-31

    ...), Federal Bureau of Investigation (FBI), proposes to establish a new system of records, the Data Integration and Visualization System, JUSTICE/FBI-021, to support and enhance data search, integration... to develop more efficient methods to analyze FBI data. The Data Integration and Visualization System...

  10. Management/Technical Interaction in Integrated Information System Development.

    ERIC Educational Resources Information Center

    Bagley, Clarence H.; Gardner, Don E.

    The integrated information system element of the management information system concept has practical applications for management in the areas of both information analysis and decision-model building. Four basic options for achieving integration in operational data systems are: a default option, the coordinated file option, the distributed…

  11. A SINS/SRS/GNS Autonomous Integrated Navigation System Based on Spectral Redshift Velocity Measurements

    PubMed Central

    Wei, Wenhui; Gao, Zhaohui; Gao, Shesheng; Jia, Ke

    2018-01-01

    In order to meet the requirements of autonomy and reliability for the navigation system, combined with the method of measuring speed by using the spectral redshift information of the natural celestial bodies, a new scheme, consisting of Strapdown Inertial Navigation System (SINS)/Spectral Redshift (SRS)/Geomagnetic Navigation System (GNS), is designed for autonomous integrated navigation systems. The principle of this SINS/SRS/GNS autonomous integrated navigation system is explored, and the corresponding mathematical model is established. Furthermore, a robust adaptive central difference particle filtering algorithm is proposed for this autonomous integrated navigation system. The simulation experiments are conducted and the results show that the designed SINS/SRS/GNS autonomous integrated navigation system possesses good autonomy, strong robustness and high reliability, thus providing a new solution for autonomous navigation technology. PMID:29642549

  12. “SLIMPLECTIC” INTEGRATORS: VARIATIONAL INTEGRATORS FOR GENERAL NONCONSERVATIVE SYSTEMS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tsang, David; Turner, Alec; Galley, Chad R.

    2015-08-10

    Symplectic integrators are widely used for long-term integration of conservative astrophysical problems due to their ability to preserve the constants of motion; however, they cannot in general be applied in the presence of nonconservative interactions. In this Letter, we develop the “slimplectic” integrator, a new type of numerical integrator that shares many of the benefits of traditional symplectic integrators yet is applicable to general nonconservative systems. We utilize a fixed-time-step variational integrator formalism applied to the principle of stationary nonconservative action developed in Galley et al. As a result, the generalized momenta and energy (Noether current) evolutions are well-tracked. Wemore » discuss several example systems, including damped harmonic oscillators, Poynting–Robertson drag, and gravitational radiation reaction, by utilizing our new publicly available code to demonstrate the slimplectic integrator algorithm. Slimplectic integrators are well-suited for integrations of systems where nonconservative effects play an important role in the long-term dynamical evolution. As such they are particularly appropriate for cosmological or celestial N-body dynamics problems where nonconservative interactions, e.g., gas interactions or dissipative tides, can play an important role.« less

  13. Information Systems Integration and Enterprise Application Integration (EAI) Adoption: A Case from Financial Services

    ERIC Educational Resources Information Center

    Lam, Wing

    2007-01-01

    Increasingly, organizations find that they need to integrate large number of information systems in order to support enterprise-wide business initiatives such as e-business, supply chain management and customer relationship management. To date, organizations have largely tended to address information systems (IS) integration in an ad-hoc manner.…

  14. Automatic visual inspection system for microelectronics

    NASA Technical Reports Server (NTRS)

    Micka, E. Z. (Inventor)

    1975-01-01

    A system for automatically inspecting an integrated circuit was developed. A device for shining a scanning narrow light beam at an integrated circuit to be inspected and another light beam at an accepted integrated circuit was included. A pair of photodetectors that receive light reflected from these integrated circuits, and a comparing system compares the outputs of the photodetectors.

  15. 76 FR 57033 - Draft Toxicological Review of n-Butanol: In Support of Summary Information on the Integrated Risk...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-15

    ... Toxicological Review of n-Butanol: In Support of Summary Information on the Integrated Risk Information System..., ``Toxicological Review of n-Butanol: In Support of Summary Information on the Integrated Risk Information System...-Butanol: In Support of Summary Information on the Integrated Risk Information System (IRIS)'' is available...

  16. What is a completely integrable nonholonomic dynamical system?

    NASA Astrophysics Data System (ADS)

    Bates, Larry; Cushman, Richard

    1999-10-01

    We compare the geometry of a toral fibration defined by the common level sets of the integrals of a Liouville integrable Hamiltonian system with a toral fibration coming from a completely integrable nonholonomic system. We illustrate their differences using the following examples: the nonholonomic oscillator, Chaplygin's skate, Routh's sphere and the rolling oblate ellipsoid of revolution.

  17. NASA UAS Integration into the NAS Project: Human Systems Integration

    NASA Technical Reports Server (NTRS)

    Shively, Jay

    2016-01-01

    This presentation provides an overview of the work the Human Systems Integration (HSI) sub-project has done on detect and avoid (DAA) displays while working on the UAS (Unmanned Aircraft System) Integration into the NAS project. The most recent simulation on DAA interoperability with Traffic Collision Avoidance System (TCAS) is discussed in the most detail. The relationship of the work to the larger UAS community and next steps are also detailed.

  18. Including safety-net providers in integrated delivery systems: issues and options for policymakers.

    PubMed

    Witgert, Katherine; Hess, Catherine

    2012-08-01

    Health care reform legislation has spurred efforts to develop integrated health care delivery systems that seek to coordinate the continuum of health services. These systems may be of particular benefit to patients who face barriers to accessing care or have multiple health conditions. But it remains to be seen how safety-net providers, including community health centers and public hospitals--which have long experience in caring for these vulnerable populations--will be included in integrated delivery systems. This issue brief explores key considerations for incorporating safety-net providers into integrated delivery systems and discusses the roles of state and federal agencies in sup­porting and testing models of integrated care delivery. The authors conclude that the most important principles in creating integrated delivery systems for vulnerable populations are: (1) an emphasis on primary care; (2) coordination of all care, including behavioral, social, and public health services; and (3) accountability for population health outcomes.

  19. Integrated nuclear data utilisation system for innovative reactors.

    PubMed

    Yamano, N; Hasegawa, A; Kato, K; Igashira, M

    2005-01-01

    A five-year research and development project on an integrated nuclear data utilisation system was initiated in 2002, for developing innovative nuclear energy systems such as accelerator-driven systems. The integrated nuclear data utilisation system will be constructed as a modular code system, which consists of two sub-systems: the nuclear data search and plotting sub-system, and the nuclear data processing and utilisation sub-system. The system will be operated with a graphical user interface in order to enable easy utilisation through the Internet by both nuclear design engineers and nuclear data evaluators. This paper presents an overview of the integrated nuclear data utilisation system, describes the development of a prototype system to examine the operability of the user interface and discusses specifications of the two sub-systems.

  20. What is Energy Systems Integration?

    ScienceCinema

    Kroposki, Ben; Lundstrom, Blake; Hannegan, Bryan; Symko-Davies, Martha

    2018-06-12

    To achieve the most efficient, flexible, and reliable energy system, NREL’s Energy Systems Integration researchers work with manufacturers, utilities, and other research organizations to find solutions to big energy challenges. This video describes the concept of energy systems integration, an approach that explores ways for energy systems to work more efficiently on their own and with each other.

  1. What is Energy Systems Integration?

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kroposki, Ben; Lundstrom, Blake; Hannegan, Bryan

    2016-10-14

    To achieve the most efficient, flexible, and reliable energy system, NREL’s Energy Systems Integration researchers work with manufacturers, utilities, and other research organizations to find solutions to big energy challenges. This video describes the concept of energy systems integration, an approach that explores ways for energy systems to work more efficiently on their own and with each other.

  2. Highly integrated digital engine control system on an F-15 airplane

    NASA Technical Reports Server (NTRS)

    Burcham, F. W., Jr.; Haering, E. A., Jr.

    1984-01-01

    The Highly Integrated Digital Electronic Control (HIDEC) program will demonstrate and evaluate the improvements in performance and mission effectiveness that result from integrated engine/airframe control systems. This system is being used on the F-15 airplane. An integrated flightpath management mode and an integrated adaptive engine stall margin mode are implemented into the system. The adaptive stall margin mode is a highly integrated mode in which the airplane flight conditions, the resulting inlet distortion, and the engine stall margin are continuously computed; the excess stall margin is used to uptrim the engine for more thrust. The integrated flightpath management mode optimizes the flightpath and throttle setting to reach a desired flight condition. The increase in thrust and the improvement in airplane performance is discussed.

  3. Integrated inertial stellar attitude sensor

    NASA Technical Reports Server (NTRS)

    Brady, Tye M. (Inventor); Kourepenis, Anthony S. (Inventor); Wyman, Jr., William F. (Inventor)

    2007-01-01

    An integrated inertial stellar attitude sensor for an aerospace vehicle includes a star camera system, a gyroscope system, a controller system for synchronously integrating an output of said star camera system and an output of said gyroscope system into a stream of data, and a flight computer responsive to said stream of data for determining from the star camera system output and the gyroscope system output the attitude of the aerospace vehicle.

  4. Integrating PV in Distributed Grids: Solutions and Technologies Workshop |

    Science.gov Websites

    Energy Systems Integration Facility | NREL Integrating PV in Distributed Grids: Solutions and Technologies Workshop Integrating PV in Distributed Grids: Solutions and Technologies Workshop In October 2015 (PV) onto the grid. The workshop was held at the Energy Systems Integration Facility. Presenters from

  5. Energy Systems Integration: Demonstrating the Grid Benefits of Connected Devices

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Overview fact sheet about the Electric Power Research Institute (EPRI) and the University of Delaware Integrated Network Testbed for Energy Grid Research and Technology Experimentation (INTEGRATE) project at the Energy Systems Integration Facility. INTEGRATE is part of the U.S. Department of Energy's Grid Modernization Initiative.

  6. Scrapping Patched Computer Systems: Integrated Data Processing for Information Management.

    ERIC Educational Resources Information Center

    Martinson, Linda

    1991-01-01

    Colleges and universities must find a way to streamline and integrate information management processes across the organization. The Georgia Institute of Technology responded to an acute problem of dissimilar operating systems with a campus-wide integrated administrative system using a machine independent relational database management system. (MSE)

  7. 77 FR 48984 - Privacy Act of 1974; System of Records Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-15

    ... General (OSG), Division of Systems Integration (DSI), Tower Oaks Building, Plaza Level 100, 1101 Wootton... Integration, at 240-453- 6085. FOR FURTHER INFORMATION CONTACT: For system 09-40-0006, contact CAPT Eric Shih, Office of the Surgeon General (OSG), Division of Systems Integration (DSI) Tower Oaks Building, Plaza...

  8. Synthesis of an integrated cockpit management system

    NASA Technical Reports Server (NTRS)

    Dasaro, J. A.; Elliott, C. T.

    1982-01-01

    The process used in the synthesis of an integrated cockpit management system was discussed. Areas covered included flight displays, subsystem management, checklists, and procedures (both normal and emergency). The process of evolving from the unintegrated conventional system to the integrated system is examined and a brief description of the results presented.

  9. Systems Analysis and Integration Publications | Transportation Research |

    Science.gov Websites

    data Vehicle analysis Vehicle energy Vehicle modeling Vehicle simulation Wireless power transfer The NREL Systems Analysis and Integration Publications Systems Analysis and Integration Publications NREL publishes technical reports, fact sheets, and other documents about its systems analysis and

  10. Integrable and superintegrable Hamiltonian systems with four dimensional real Lie algebras as symmetry of the systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Abedi-Fardad, J., E-mail: j.abedifardad@bonabu.ac.ir; Rezaei-Aghdam, A., E-mail: rezaei-a@azaruniv.edu; Haghighatdoost, Gh., E-mail: gorbanali@azaruniv.edu

    2014-05-15

    We construct integrable and superintegrable Hamiltonian systems using the realizations of four dimensional real Lie algebras as a symmetry of the system with the phase space R{sup 4} and R{sup 6}. Furthermore, we construct some integrable and superintegrable Hamiltonian systems for which the symmetry Lie group is also the phase space of the system.

  11. Identifying Challenges to the Integration of Computer-Based Surveillance Information Systems in a Large City Health Department: A Case Study.

    PubMed

    Jennings, Jacky M; Stover, Jeffrey A; Bair-Merritt, Megan H; Fichtenberg, Caroline; Munoz, Mary Grace; Maziad, Rafiq; Ketemepi, Sherry Johnson; Zenilman, Jonathan

    2009-01-01

    Integrated infectious disease surveillance information systems have the potential to provide important new surveillance capacities and business efficiencies for local health departments. We conducted a case study at a large city health department of the primary computer-based infectious disease surveillance information systems during a 10-year period to identify the major challenges for information integration across the systems. The assessment included key informant interviews and evaluations of the computer-based surveillance information systems used for acute communicable diseases, human immunodeficiency virus/acquired immunodeficiency syndrome, sexually transmitted diseases, and tuberculosis. Assessments were conducted in 1998 with a follow-up in 2008. Assessments specifically identified and described the primary computer-based surveillance information system, any duplicative information systems, and selected variables collected. Persistent challenges to information integration across the information systems included the existence of duplicative data systems, differences in the variables used to collect similar information, and differences in basic architecture. The assessments identified a number of challenges for information integration across the infectious disease surveillance information systems at this city health department. The results suggest that local disease control programs use computer-based surveillance information systems that were not designed for data integration. To the extent that integration provides important new surveillance capacities and business efficiencies, we recommend that patient-centric information systems be designed that provide all the epidemiologic, clinical, and research needs in one system. In addition, the systems should include a standard system of elements and fields across similar surveillance systems.

  12. Assuring structural integrity in Army systems

    NASA Technical Reports Server (NTRS)

    1985-01-01

    The object of this study was to recommend possible improvements in the manner in which structural integrity of Army systems is assured. The elements of a structural integrity program are described, and relevant practices used in various industries and government organizations are reviewed. Some case histories of Army weapon systems are examined. The mandatory imposition of a structural integrity program patterned after the Air Force Aircraft Structural Integrity Program is recommended and the benefits of such an action are identified.

  13. The Vanguard of Community-based Integrated Care in Japan: The Effect of a Rural Town on National Policy

    PubMed Central

    Matsumoto, Masatoshi; Okita, Mitsuaki; Inoue, Kazuo; Takeuchi, Keisuke; Tsutsui, Takako; Nishimura, Shuhei; Hayashi, Takuo

    2017-01-01

    Introduction: Japan has the largest percentage of elderly people in the world. In 2012 the government implemented a community-based integrated care system which provides seamless community healthcare resources for elderly people with chronic diseases and disabilities. Methods: This paper describes the challenges of establishing a community-based integrated care system in 1974 in Mitsugi, a rural town of Japan. This system has influenced the government and become the model for the nationwide system. Results: In the 1970s, Mitsugi’s aging population was growing faster than Japan’s, but elder care was fragmented among a variety of service sections. A community-based integrated care system evolved because of the small but aging population size and the initiative of some local leaders of medical care and politics. After the system took effect, the proportion of bedridden people and medical care costs for the elderly dropped in Mitsugi while it continued to rise everywhere else in Japan. Mitsugi’s community-based integrated care system is now shaping national policy. Conclusion: Mitsugi is in the vanguard of Japan’s community-based integrated care system. The case showed the community-based integrated care system can diffuse from rural to urban areas. PMID:28970743

  14. A Strapdown Interial Navigation System/Beidou/Doppler Velocity Log Integrated Navigation Algorithm Based on a Cubature Kalman Filter

    PubMed Central

    Gao, Wei; Zhang, Ya; Wang, Jianguo

    2014-01-01

    The integrated navigation system with strapdown inertial navigation system (SINS), Beidou (BD) receiver and Doppler velocity log (DVL) can be used in marine applications owing to the fact that the redundant and complementary information from different sensors can markedly improve the system accuracy. However, the existence of multisensor asynchrony will introduce errors into the system. In order to deal with the problem, conventionally the sampling interval is subdivided, which increases the computational complexity. In this paper, an innovative integrated navigation algorithm based on a Cubature Kalman filter (CKF) is proposed correspondingly. A nonlinear system model and observation model for the SINS/BD/DVL integrated system are established to more accurately describe the system. By taking multi-sensor asynchronization into account, a new sampling principle is proposed to make the best use of each sensor's information. Further, CKF is introduced in this new algorithm to enable the improvement of the filtering accuracy. The performance of this new algorithm has been examined through numerical simulations. The results have shown that the positional error can be effectively reduced with the new integrated navigation algorithm. Compared with the traditional algorithm based on EKF, the accuracy of the SINS/BD/DVL integrated navigation system is improved, making the proposed nonlinear integrated navigation algorithm feasible and efficient. PMID:24434842

  15. System Engineering and Integration of Controls for Advanced Life Support

    NASA Technical Reports Server (NTRS)

    Overland, David; Hoo, Karlene; Ciskowski, Marvin

    2006-01-01

    The Advanced Integration Matrix (AIM) project at the Johnson Space Center (JSC) was chartered to study and solve systems-level integration issues for exploration missions. One of the first issues identified was an inability to conduct trade studies on control system architectures due to the absence of mature evaluation criteria. Such architectures are necessary to enable integration of regenerative life support systems. A team was formed to address issues concerning software and hardware architectures and system controls.. The team has investigated what is required to integrate controls for the types of non-linear dynamic systems encountered in advanced life support. To this end, a water processing bioreactor testbed is being developed which will enable prototyping and testing of integration strategies and technologies. Although systems such as the water bioreactors exhibit the complexities of interactions between control schemes most vividly, it is apparent that this behavior and its attendant risks will manifest itself among any set of interdependent autonomous control systems. A methodology for developing integration requirements for interdependent and autonomous systems is a goal of this team and this testbed. This paper is a high-level summary of the current status of the investigation, the issues encountered, some tentative conclusions, and the direction expected for further research.

  16. Comparative health systems research among Kaiser Permanente and other integrated delivery systems: a systematic literature review.

    PubMed

    Maeda, Jared Lane K; Lee, Karen M; Horberg, Michael

    2014-01-01

    Because of rising health care costs, wide variations in quality, and increased patient complexity, the US health care system is undergoing rapid changes that include payment reform and movement toward integrated delivery systems. Well-established integrated delivery systems, such as Kaiser Permanente (KP), should work to identify the specific system-level factors that result in superior patient outcomes in response to policymakers' concerns. Comparative health systems research can provide insights into which particular aspects of the integrated delivery system result in improved care delivery. To provide a baseline understanding of comparative health systems research related to integrated delivery systems and KP. Systematic literature review. We conducted a literature search on PubMed and the KP Publications Library. Studies that compared KP as a system or organization with other health care systems or across KP facilities internally were included. The literature search identified 1605 articles, of which 65 met the study inclusion criteria and were examined by 3 reviewers. Most comparative health systems studies focused on intra-KP comparisons (n = 42). Fewer studies compared KP with other US (n = 15) or international (n = 12) health care systems. Several themes emerged from the literature as possible factors that may contribute to improved care delivery in integrated delivery systems. Of all studies published by or about KP, only a small proportion of articles (4%) was identified as being comparative health systems research. Additional empirical studies that compare the specific factors of the integrated delivery system model with other systems of care are needed to better understand the "system-level" factors that result in improved and/or diminished care delivery.

  17. Modular Architecture for Integrated Model-Based Decision Support.

    PubMed

    Gaebel, Jan; Schreiber, Erik; Oeser, Alexander; Oeltze-Jafra, Steffen

    2018-01-01

    Model-based decision support systems promise to be a valuable addition to oncological treatments and the implementation of personalized therapies. For the integration and sharing of decision models, the involved systems must be able to communicate with each other. In this paper, we propose a modularized architecture of dedicated systems for the integration of probabilistic decision models into existing hospital environments. These systems interconnect via web services and provide model sharing and processing capabilities for clinical information systems. Along the lines of IHE integration profiles from other disciplines and the meaningful reuse of routinely recorded patient data, our approach aims for the seamless integration of decision models into hospital infrastructure and the physicians' daily work.

  18. Design distributed simulation platform for vehicle management system

    NASA Astrophysics Data System (ADS)

    Wen, Zhaodong; Wang, Zhanlin; Qiu, Lihua

    2006-11-01

    Next generation military aircraft requires the airborne management system high performance. General modules, data integration, high speed data bus and so on are needed to share and manage information of the subsystems efficiently. The subsystems include flight control system, propulsion system, hydraulic power system, environmental control system, fuel management system, electrical power system and so on. The unattached or mixed architecture is changed to integrated architecture. That means the whole airborne system is regarded into one system to manage. So the physical devices are distributed but the system information is integrated and shared. The process function of each subsystem are integrated (including general process modules, dynamic reconfiguration), furthermore, the sensors and the signal processing functions are shared. On the other hand, it is a foundation for power shared. Establish a distributed vehicle management system using 1553B bus and distributed processors which can provide a validation platform for the research of airborne system integrated management. This paper establishes the Vehicle Management System (VMS) simulation platform. Discuss the software and hardware configuration and analyze the communication and fault-tolerant method.

  19. Chip-scale sensor system integration for portable health monitoring.

    PubMed

    Jokerst, Nan M; Brooke, Martin A; Cho, Sang-Yeon; Shang, Allan B

    2007-12-01

    The revolution in integrated circuits over the past 50 yr has produced inexpensive computing and communications systems that are powerful and portable. The technologies for these integrated chip-scale sensing systems, which will be miniature, lightweight, and portable, are emerging with the integration of sensors with electronics, optical systems, micromachines, microfluidics, and the integration of chemical and biological materials (soft/wet material integration with traditional dry/hard semiconductor materials). Hence, we stand at a threshold for health monitoring technology that promises to provide wearable biochemical sensing systems that are comfortable, inauspicious, wireless, and battery-operated, yet that continuously monitor health status, and can transmit compressed data signals at regular intervals, or alarm conditions immediately. In this paper, we explore recent results in chip-scale sensor integration technology for health monitoring. The development of inexpensive chip-scale biochemical optical sensors, such as microresonators, that are customizable for high sensitivity coupled with rapid prototyping will be discussed. Ground-breaking work in the integration of chip-scale optical systems to support these optical sensors will be highlighted, and the development of inexpensive Si complementary metal-oxide semiconductor circuitry (which makes up the vast majority of computational systems today) for signal processing and wireless communication with local receivers that lie directly on the chip-scale sensor head itself will be examined.

  20. Role of IAC in large space systems thermal analysis

    NASA Technical Reports Server (NTRS)

    Jones, G. K.; Skladany, J. T.; Young, J. P.

    1982-01-01

    Computer analysis programs to evaluate critical coupling effects that can significantly influence spacecraft system performance are described. These coupling effects arise from the varied parameters of the spacecraft systems, environments, and forcing functions associated with disciplines such as thermal, structures, and controls. Adverse effects can be expected to significantly impact system design aspects such as structural integrity, controllability, and mission performance. One such needed design analysis capability is a software system that can integrate individual discipline computer codes into a highly user-oriented/interactive-graphics-based analysis capability. The integrated analysis capability (IAC) system can be viewed as: a core framework system which serves as an integrating base whereby users can readily add desired analysis modules and as a self-contained interdisciplinary system analysis capability having a specific set of fully integrated multidisciplinary analysis programs that deal with the coupling of thermal, structures, controls, antenna radiation performance, and instrument optical performance disciplines.

  1. Introducing WISDEM:An Integrated System Modeling for Wind Turbines and Plant (Presentation)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dykes, K.; Graf, P.; Scott, G.

    2015-01-01

    The National Wind Technology Center wind energy systems engineering initiative has developed an analysis platform to leverage its research capabilities toward integrating wind energy engineering and cost models across wind plants. This Wind-Plant Integrated System Design & Engineering Model (WISDEM) platform captures the important interactions between various subsystems to achieve a better National Wind Technology Center wind energy systems engineering initiative has developed an analysis platform to leverage its research capabilities toward integrating wind energy engineering and cost models across wind plants. This Wind-Plant Integrated System Design & Engineering Model (WISDEM) platform captures the important interactions between various subsystems tomore » achieve a better understanding of how to improve system-level performance and achieve system-level cost reductions. This work illustrates a few case studies with WISDEM that focus on the design and analysis of wind turbines and plants at different system levels.« less

  2. Comprehensive Anti-error Study on Power Grid Dispatching Based on Regional Regulation and Integration

    NASA Astrophysics Data System (ADS)

    Zhang, Yunju; Chen, Zhongyi; Guo, Ming; Lin, Shunsheng; Yan, Yinyang

    2018-01-01

    With the large capacity of the power system, the development trend of the large unit and the high voltage, the scheduling operation is becoming more frequent and complicated, and the probability of operation error increases. This paper aims at the problem of the lack of anti-error function, single scheduling function and low working efficiency for technical support system in regional regulation and integration, the integrated construction of the error prevention of the integrated architecture of the system of dispatching anti - error of dispatching anti - error of power network based on cloud computing has been proposed. Integrated system of error prevention of Energy Management System, EMS, and Operation Management System, OMS have been constructed either. The system architecture has good scalability and adaptability, which can improve the computational efficiency, reduce the cost of system operation and maintenance, enhance the ability of regional regulation and anti-error checking with broad development prospects.

  3. Copernicus Architecture, Phase I: Requirements Definition

    DTIC Science & Technology

    1991-08-01

    control primarily over maritime patrol aircraft (MPA) and Integrated Undersea Surveillance System (IUSS) units; however, surface ships and other units...Intermediate System Integrated Services Digital Network Integrated Tactical-Stategic Data Network Integrated Undersea Surveillance System Joint Army Navy... TTE Technical Training Equipment TTY Teletype UFO UHF Follow On UHF Ultra High Frequency USA/USAF U. S. Army/U.S. Air Force USCINC U. S

  4. 76 FR 71029 - Draft Toxicological Review of n-Butanol: In Support of Summary Information on the Integrated Risk...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-16

    ... Toxicological Review of n-Butanol: In Support of Summary Information on the Integrated Risk Information System... Information on the Integrated Risk Information System (IRIS)'' (EPA/635/R-11/081A). On September 15, 2011, the... ``Toxicological Review of n-Butanol: In Support of Summary Information on the Integrated Risk Information System...

  5. Ship to Shore Data Communication and Prioritization

    DTIC Science & Technology

    2011-12-01

    First Out FTP File Transfer Protocol GCCS-M Global Command and Control System Maritime HAIPE High Assurance Internet Protocol Encryptor HTTP Hypertext...Transfer Protocol (world wide web protocol ) IBS Integrated Bar Code System IDEF0 Integration Definition IER Information Exchange Requirements...INTEL Intelligence IP Internet Protocol IPT Integrated Product Team ISEA In-Service Engineering Agent ISNS Integrated Shipboard Network System IT

  6. Evaluation of exercise-respiratory system modifications and integration schemes for physiological systems

    NASA Technical Reports Server (NTRS)

    Gallagher, R. R.

    1974-01-01

    Exercise subroutine modifications are implemented in an exercise-respiratory system model yielding improvement of system response to exercise forcings. A more physiologically desirable respiratory ventilation rate in addition to an improved regulation of arterial gas tensions and cerebral blood flow is observed. A respiratory frequency expression is proposed which would be appropriate as an interfacing element of the respiratory-pulsatile cardiovascular system. Presentation of a circulatory-respiratory system integration scheme along with its computer program listing is given. The integrated system responds to exercise stimulation for both nonstressed and stressed physiological states. Other integration possibilities are discussed with respect to the respiratory, pulsatile cardiovascular, thermoregulatory, and the long-term circulatory systems.

  7. Optimation of Operation System Integration between Main and Feeder Public Transport (Case Study: Trans Jakarta-Kopaja Bus Services)

    NASA Astrophysics Data System (ADS)

    Miharja, M.; Priadi, Y. N.

    2018-05-01

    Promoting a better public transport is a key strategy to cope with urban transport problems which are mostly caused by a huge private vehicle usage. A better public transport service quality not only focuses on one type of public transport mode, but also concerns on inter modes service integration. Fragmented inter mode public transport service leads to a longer trip chain as well as average travel time which would result in its failure to compete with a private vehicle. This paper examines the optimation process of operation system integration between Trans Jakarta Bus as the main public transport mode and Kopaja Bus as feeder public transport service in Jakarta. Using scoring-interview method combined with standard parameters in operation system integration, this paper identifies the key factors that determine the success of the two public transport operation system integrations. The study found that some key integration parameters, such as the cancellation of “system setoran”, passenger get in-get out at official stop points, and systematic payment, positively contribute to a better service integration. However, some parameters such as fine system, time and changing point reliability, and information system reliability are among those which need improvement. These findings are very useful for the authority to set the right strategy to improve operation system integration between Trans Jakarta and Kopaja Bus services.

  8. Integrated energy balance analysis for Space Station Freedom

    NASA Technical Reports Server (NTRS)

    Tandler, John

    1991-01-01

    An integrated simulation model is described which characterizes the dynamic interaction of the energy transport subsystems of Space Station Freedom for given orbital conditions and for a given set of power and thermal loads. Subsystems included in the model are the Electric Power System (EPS), the Internal Thermal Control System (ITCS), the External Thermal Control System (ETCS), and the cabin Temperature and Humidity Control System (THC) (which includes the avionics air cooling, cabin air cooling, and intermodule ventilation systems). Models of the subsystems were developed in a number of system-specific modeling tools and validated. The subsystem models are then combined into integrated models to address a number of integrated performance issues involving the ability of the integrated energy transport system of Space Station Freedom to provide power, controlled cabin temperature and humidity, and equipment thermal control to support operations.

  9. Choosing the Right Integrator for Your Building Automation Project.

    ERIC Educational Resources Information Center

    Podgorski, Will

    2002-01-01

    Examines the prevailing definitions and responsibilities of product, network, and system integrators for building automation systems; offers a novel approach to system integration; and sets realistic expectations for the owner in terms of benefits, outcomes, and overall values. (EV)

  10. 48 CFR 1034.202 - Integrated Baseline Reviews.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... which the management process provides effective and integrated technical/schedule/cost planning and... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Integrated Baseline... SPECIAL CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 1034.202...

  11. Developing an Integrated Information System for the Food Sector. Agricultural Economic Report No. 575.

    ERIC Educational Resources Information Center

    Manchester, Alden

    This document proposes an information system for the food sector that integrates measures of prices, quantities, and values. It suggests that such an integrated information system provides more information about many developments in the food sector than a system that separately measures prices, quantities, or values. Concepts and approaches…

  12. 28 CFR 25.5 - Validation and data integrity of records in the system.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 1 2011-07-01 2011-07-01 false Validation and data integrity of records in the system. 25.5 Section 25.5 Judicial Administration DEPARTMENT OF JUSTICE DEPARTMENT OF JUSTICE INFORMATION SYSTEMS The National Instant Criminal Background Check System § 25.5 Validation and data integrity...

  13. 28 CFR 25.5 - Validation and data integrity of records in the system.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 1 2013-07-01 2013-07-01 false Validation and data integrity of records in the system. 25.5 Section 25.5 Judicial Administration DEPARTMENT OF JUSTICE DEPARTMENT OF JUSTICE INFORMATION SYSTEMS The National Instant Criminal Background Check System § 25.5 Validation and data integrity...

  14. 28 CFR 25.5 - Validation and data integrity of records in the system.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 1 2012-07-01 2012-07-01 false Validation and data integrity of records in the system. 25.5 Section 25.5 Judicial Administration DEPARTMENT OF JUSTICE DEPARTMENT OF JUSTICE INFORMATION SYSTEMS The National Instant Criminal Background Check System § 25.5 Validation and data integrity...

  15. 28 CFR 25.5 - Validation and data integrity of records in the system.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 1 2014-07-01 2014-07-01 false Validation and data integrity of records in the system. 25.5 Section 25.5 Judicial Administration DEPARTMENT OF JUSTICE DEPARTMENT OF JUSTICE INFORMATION SYSTEMS The National Instant Criminal Background Check System § 25.5 Validation and data integrity...

  16. Testing of an Integrated Reactor Core Simulator and Power Conversion System with Simulated Reactivity Feedback

    NASA Technical Reports Server (NTRS)

    Bragg-Sitton, Shannon M.; Hervol, David S.; Godfroy, Thomas J.

    2009-01-01

    A Direct Drive Gas-Cooled (DDG) reactor core simulator has been coupled to a Brayton Power Conversion Unit (BPCU) for integrated system testing at NASA Glenn Research Center (GRC) in Cleveland, OH. This is a closed-cycle system that incorporates an electrically heated reactor core module, turbo alternator, recuperator, and gas cooler. Nuclear fuel elements in the gas-cooled reactor design are replaced with electric resistance heaters to simulate the heat from nuclear fuel in the corresponding fast spectrum nuclear reactor. The thermodynamic transient behavior of the integrated system was the focus of this test series. In order to better mimic the integrated response of the nuclear-fueled system, a simulated reactivity feedback control loop was implemented. Core power was controlled by a point kinetics model in which the reactivity feedback was based on core temperature measurements; the neutron generation time and the temperature feedback coefficient are provided as model inputs. These dynamic system response tests demonstrate the overall capability of a non-nuclear test facility in assessing system integration issues and characterizing integrated system response times and response characteristics.

  17. Testing of an Integrated Reactor Core Simulator and Power Conversion System with Simulated Reactivity Feedback

    NASA Technical Reports Server (NTRS)

    Bragg-Sitton, Shannon M.; Hervol, David S.; Godfroy, Thomas J.

    2010-01-01

    A Direct Drive Gas-Cooled (DDG) reactor core simulator has been coupled to a Brayton Power Conversion Unit (BPCU) for integrated system testing at NASA Glenn Research Center (GRC) in Cleveland, Ohio. This is a closed-cycle system that incorporates an electrically heated reactor core module, turboalternator, recuperator, and gas cooler. Nuclear fuel elements in the gas-cooled reactor design are replaced with electric resistance heaters to simulate the heat from nuclear fuel in the corresponding fast spectrum nuclear reactor. The thermodynamic transient behavior of the integrated system was the focus of this test series. In order to better mimic the integrated response of the nuclear-fueled system, a simulated reactivity feedback control loop was implemented. Core power was controlled by a point kinetics model in which the reactivity feedback was based on core temperature measurements; the neutron generation time and the temperature feedback coefficient are provided as model inputs. These dynamic system response tests demonstrate the overall capability of a non-nuclear test facility in assessing system integration issues and characterizing integrated system response times and response characteristics.

  18. Modular integration of electronics and microfluidic systems using flexible printed circuit boards.

    PubMed

    Wu, Amy; Wang, Lisen; Jensen, Erik; Mathies, Richard; Boser, Bernhard

    2010-02-21

    Microfluidic systems offer an attractive alternative to conventional wet chemical methods with benefits including reduced sample and reagent volumes, shorter reaction times, high-throughput, automation, and low cost. However, most present microfluidic systems rely on external means to analyze reaction products. This substantially adds to the size, complexity, and cost of the overall system. Electronic detection based on sub-millimetre size integrated circuits (ICs) has been demonstrated for a wide range of targets including nucleic and amino acids, but deployment of this technology to date has been limited due to the lack of a flexible process to integrate these chips within microfluidic devices. This paper presents a modular and inexpensive process to integrate ICs with microfluidic systems based on standard printed circuit board (PCB) technology to assemble the independently designed microfluidic and electronic components. The integrated system can accommodate multiple chips of different sizes bonded to glass or PDMS microfluidic systems. Since IC chips and flex PCB manufacturing and assembly are industry standards with low cost, the integrated system is economical for both laboratory and point-of-care settings.

  19. Assessment of Intelligent Tutoring Systems Technologies and Opportunities (Evaluation et opportunites des technologies des systemes de tutorat intelligents)

    DTIC Science & Technology

    2018-01-01

    His research designs adaptive systems for online content, by integrating research in psychology and education, human- ANNEX A − INTELLIGENT TUTORING...related scientific activities that include systems engineering, operational research and analysis, synthesis, integration and validation of knowledge...System Analysis and Studies Panel • SCI Systems Concepts and Integration Panel • SET Sensors and Electronics Technology Panel These Panels and Group

  20. Highly integrated digital engine control system on an F-15 airplane

    NASA Technical Reports Server (NTRS)

    Burcham, F. W., Jr.; Haering, E. A., Jr.

    1984-01-01

    The highly integrated digital electronic control (HIDEC) program will demonstrate and evaluate the improvements in performance and mission effectiveness that result from integrated engine-airframe control systems. This system is being used on the F-15 airplane at the Dryden Flight Research Facility of NASA Ames Research Center. An integrated flightpath management mode and an integrated adaptive engine stall margin mode are being implemented into the system. The adaptive stall margin mode is a highly integrated mode in which the airplane flight conditions, the resulting inlet distortion, and the engine stall margin are continuously computed; the excess stall margin is used to uptrim the engine for more thrust. The integrated flightpath management mode optimizes the flightpath and throttle setting to reach a desired flight condition. The increase in thrust and the improvement in airplane performance is discussed in this paper.

  1. Digital Earth system based river basin data integration

    NASA Astrophysics Data System (ADS)

    Zhang, Xin; Li, Wanqing; Lin, Chao

    2014-12-01

    Digital Earth is an integrated approach to build scientific infrastructure. The Digital Earth systems provide a three-dimensional visualization and integration platform for river basin data which include the management data, in situ observation data, remote sensing observation data and model output data. This paper studies the Digital Earth system based river basin data integration technology. Firstly, the construction of the Digital Earth based three-dimensional river basin data integration environment is discussed. Then the river basin management data integration technology is presented which is realized by general database access interface, web service and ActiveX control. Thirdly, the in situ data stored in database tables as records integration is realized with three-dimensional model of the corresponding observation apparatus display in the Digital Earth system by a same ID code. In the next two parts, the remote sensing data and the model output data integration technologies are discussed in detail. The application in the Digital Zhang River basin System of China shows that the method can effectively improve the using efficiency and visualization effect of the data.

  2. Study of noise propagation and the effects of insufficient numbers of projection angles and detector samplings for iterative reconstruction using planar-integral data

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang, B.; Zeng, G. L.

    2006-09-15

    A rotating slat collimator can be used to acquire planar-integral data. It achieves higher geometric efficiency than a parallel-hole collimator by accepting more photons, but the planar-integral data contain less tomographic information that may result in larger noise amplification in the reconstruction. Lodge evaluated the rotating slat system and the parallel-hole system based on noise behavior for an FBP reconstruction. Here, we evaluate the noise propagation properties of the two collimation systems for iterative reconstruction. We extend Huesman's noise propagation analysis of the line-integral system to the planar-integral case, and show that approximately 2.0(D/dp) SPECT angles, 2.5(D/dp) self-spinning angles atmore » each detector position, and a 0.5dp detector sampling interval are required in order for the planar-integral data to be efficiently utilized. Here, D is the diameter of the object and dp is the linear dimension of the voxels that subdivide the object. The noise propagation behaviors of the two systems are then compared based on a least-square reconstruction using the ratio of the SNR in the image reconstructed using a planar-integral system to that reconstructed using a line-integral system. The ratio is found to be proportional to {radical}(F/D), where F is a geometric efficiency factor. This result has been verified by computer simulations. It confirms that for an iterative reconstruction, the noise tradeoff of the two systems is not only dependent on the increase of the geometric efficiency afforded by the planar projection method, but also dependent on the size of the object. The planar-integral system works better for small objects, while the line-integral system performs better for large ones. This result is consistent with Lodge's results based on the FBP method.« less

  3. Engineering Elegant Systems: Postulates, Principles, and Hypotheses of Systems Engineering

    NASA Technical Reports Server (NTRS)

    Watson, Michael D.

    2018-01-01

    Definition: System Engineering is the engineering discipline which integrates the system functions, system environment, and the engineering disciplines necessary to produce and/or operate an elegant system; Elegant System - A system that is robust in application, fully meeting specified and adumbrated intent, is well structured, and is graceful in operation. Primary Focus: System Design and Integration: Identify system couplings and interactions; Identify system uncertainties and sensitivities; Identify emergent properties; Manage the effectiveness of the system. Engineering Discipline Integration: Manage flow of information for system development and/or operations; Maintain system activities within budget and schedule. Supporting Activities: Process application and execution.

  4. Creating organizational value by leveraging the multihospital pharmacy enterprise.

    PubMed

    Schenkat, Dan; Rough, Steve; Hansen, Amanda; Chen, David; Knoer, Scott

    2018-04-01

    The results of a survey of multihospital pharmacy leaders are summarized, and a road map for creating organizational value with the pharmacy enterprise is presented. A survey was designed to evaluate the level of integration of pharmacy services across each system's multiple hospitals, determine the most commonly integrated services, determine whether value was quantified when services were integrated, collect common barriers for finding value through integration, and identify strategies for successfully overcoming these barriers. The comprehensive, 59-question survey was distributed electronically in September 2016 to the top pharmacy executive at approximately 160 multihospital systems located throughout the United States. Survey respondents indicated that health systems are taking a wide range of approaches to integrating services systemwide. Several themes emerged from the survey responses: (1) having a system-level pharmacy leader with solid-line reporting across the enterprise increased the likelihood of integrating pharmacy services effectively, (2) integration of pharmacy services across a multihospital system was unlikely to decrease the number of pharmacy full-time equivalents within the enterprise, and (3) significant opportunities exist for creating value for the multihospital health system with the pharmacy enterprise, particularly within 4 core areas: system-level drug formulary and clinical standardization initiatives, supply chain initiatives, electronic health record integration, and specialty and retail pharmacy services. Consistently demonstrating strong organizational leadership, entrepreneurialism, and the ability to create value for the organization will lead to the system-level pharmacy leader and the pharmacy enterprise being well-positioned to achieve positive outcomes for patients, payers, and the broader health system. Copyright © 2018 by the American Society of Health-System Pharmacists, Inc. All rights reserved.

  5. Project management plan : Dallas Integrated Corridor Management (ICM) demonstration project.

    DOT National Transportation Integrated Search

    2010-12-01

    The Dallas Integrated Corridor Management System Demonstration Project is a multi-agency, de-centralized operation which will utilize a set of regional systems to integrate the operations of the corridor. The purpose of the Dallas ICM System is to im...

  6. Integrated Vehicle-Based Safety Systems (IVBSS) Light Vehicle Field Operational Test Independent Evaluation

    DOT National Transportation Integrated Search

    2011-10-01

    This report presents the methodology and results of the independent evaluation of a prototype integrated crash warning system for : light vehicles as part of the Integrated Vehicle-Based Safety Systems initiative of the United States Department of : ...

  7. 12. Exterior view, showing tank and piping associated with Test ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. Exterior view, showing tank and piping associated with Test Cell 7, Systems Integration Laboratory Building (T-28), looking west. - Air Force Plant PJKS, Systems Integration Laboratory, Systems Integration Laboratory Building, Waterton Canyon Road & Colorado Highway 121, Lakewood, Jefferson County, CO

  8. Autonomous Integrated Receive System (AIRS) requirements definition. Volume 4: Functional specification for the prototype Automated Integrated Receive System (AIRS)

    NASA Technical Reports Server (NTRS)

    Chie, C. M.

    1984-01-01

    The functional requirements for the performance, design, and testing for the prototype Automated Integrated Receive System (AIRS) to be demonstrated for the TDRSS S-Band Single Access Return Link are presented.

  9. Hyperelliptic Prym Varieties and Integrable Systems

    NASA Astrophysics Data System (ADS)

    Fernandes, Rui Loja; Vanhaecke, Pol

    We introduce two algebraic completely integrable analogues of the Mumford systems which we call hyperelliptic Prym systems, because every hyperelliptic Prym variety appears as a fiber of their momentum map. As an application we show that the general fiber of the momentum map of the periodic Volterra lattice is an affine part of a hyperelliptic Prym variety, obtained by removing n translates of the theta divisor, and we conclude that this integrable system is algebraic completely integrable.

  10. Development of integrated control system for smart factory in the injection molding process

    NASA Astrophysics Data System (ADS)

    Chung, M. J.; Kim, C. Y.

    2018-03-01

    In this study, we proposed integrated control system for automation of injection molding process required for construction of smart factory. The injection molding process consists of heating, tool close, injection, cooling, tool open, and take-out. Take-out robot controller, image processing module, and process data acquisition interface module are developed and assembled to integrated control system. By adoption of integrated control system, the injection molding process can be simplified and the cost for construction of smart factory can be inexpensive.

  11. Measuring Integrated Information from the Decoding Perspective

    PubMed Central

    Oizumi, Masafumi; Amari, Shun-ichi; Yanagawa, Toru; Fujii, Naotaka; Tsuchiya, Naotsugu

    2016-01-01

    Accumulating evidence indicates that the capacity to integrate information in the brain is a prerequisite for consciousness. Integrated Information Theory (IIT) of consciousness provides a mathematical approach to quantifying the information integrated in a system, called integrated information, Φ. Integrated information is defined theoretically as the amount of information a system generates as a whole, above and beyond the amount of information its parts independently generate. IIT predicts that the amount of integrated information in the brain should reflect levels of consciousness. Empirical evaluation of this theory requires computing integrated information from neural data acquired from experiments, although difficulties with using the original measure Φ precludes such computations. Although some practical measures have been previously proposed, we found that these measures fail to satisfy the theoretical requirements as a measure of integrated information. Measures of integrated information should satisfy the lower and upper bounds as follows: The lower bound of integrated information should be 0 and is equal to 0 when the system does not generate information (no information) or when the system comprises independent parts (no integration). The upper bound of integrated information is the amount of information generated by the whole system. Here we derive the novel practical measure Φ* by introducing a concept of mismatched decoding developed from information theory. We show that Φ* is properly bounded from below and above, as required, as a measure of integrated information. We derive the analytical expression of Φ* under the Gaussian assumption, which makes it readily applicable to experimental data. Our novel measure Φ* can generally be used as a measure of integrated information in research on consciousness, and also as a tool for network analysis on diverse areas of biology. PMID:26796119

  12. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shahidehpour, Mohammad

    Integrating 20% or more wind energy into the system and transmitting large sums of wind energy over long distances will require a decision making capability that can handle very large scale power systems with tens of thousands of buses and lines. There is a need to explore innovative analytical and implementation solutions for continuing reliable operations with the most economical integration of additional wind energy in power systems. A number of wind integration solution paths involve the adoption of new operating policies, dynamic scheduling of wind power across interties, pooling integration services, and adopting new transmission scheduling practices. Such practicesmore » can be examined by the decision tool developed by this project. This project developed a very efficient decision tool called Wind INtegration Simulator (WINS) and applied WINS to facilitate wind energy integration studies. WINS focused on augmenting the existing power utility capabilities to support collaborative planning, analysis, and wind integration project implementations. WINS also had the capability of simulating energy storage facilities so that feasibility studies of integrated wind energy system applications can be performed for systems with high wind energy penetrations. The development of WINS represents a major expansion of a very efficient decision tool called POwer Market Simulator (POMS), which was developed by IIT and has been used extensively for power system studies for decades. Specifically, WINS provides the following superiorities; (1) An integrated framework is included in WINS for the comprehensive modeling of DC transmission configurations, including mono-pole, bi-pole, tri-pole, back-to-back, and multi-terminal connection, as well as AC/DC converter models including current source converters (CSC) and voltage source converters (VSC); (2) An existing shortcoming of traditional decision tools for wind integration is the limited availability of user interface, i.e., decision results are often text-based demonstrations. WINS includes a powerful visualization tool and user interface capability for transmission analyses, planning, and assessment, which will be of great interest to power market participants, power system planners and operators, and state and federal regulatory entities; and (3) WINS can handle extended transmission models for wind integration studies. WINS models include limitations on transmission flow as well as bus voltage for analyzing power system states. The existing decision tools often consider transmission flow constraints (dc power flow) alone which could result in the over-utilization of existing resources when analyzing wind integration. WINS can be used to assist power market participants including transmission companies, independent system operators, power system operators in vertically integrated utilities, wind energy developers, and regulatory agencies to analyze economics, security, and reliability of various options for wind integration including transmission upgrades and the planning of new transmission facilities. WINS can also be used by industry for the offline training of reliability and operation personnel when analyzing wind integration uncertainties, identifying critical spots in power system operation, analyzing power system vulnerabilities, and providing credible decisions for examining operation and planning options for wind integration. Researches in this project on wind integration included (1) Development of WINS; (2) Transmission Congestion Analysis in the Eastern Interconnection; (3) Analysis of 2030 Large-Scale Wind Energy Integration in the Eastern Interconnection; (4) Large-scale Analysis of 2018 Wind Energy Integration in the Eastern U.S. Interconnection. The research resulted in 33 papers, 9 presentations, 9 PhD degrees, 4 MS degrees, and 7 awards. The education activities in this project on wind energy included (1) Wind Energy Training Facility Development; (2) Wind Energy Course Development.« less

  13. Systems and methods for an integrated electrical sub-system powered by wind energy

    DOEpatents

    Liu, Yan [Ballston Lake, NY; Garces, Luis Jose [Niskayuna, NY

    2008-06-24

    Various embodiments relate to systems and methods related to an integrated electrically-powered sub-system and wind power system including a wind power source, an electrically-powered sub-system coupled to and at least partially powered by the wind power source, the electrically-powered sub-system being coupled to the wind power source through power converters, and a supervisory controller coupled to the wind power source and the electrically-powered sub-system to monitor and manage the integrated electrically-powered sub-system and wind power system.

  14. Research a Novel Integrated and Dynamic Multi-object Trade-Off Mechanism in Software Project

    NASA Astrophysics Data System (ADS)

    Jiang, Weijin; Xu, Yuhui

    Aiming at practical requirements of present software project management and control, the paper presented to construct integrated multi-object trade-off model based on software project process management, so as to actualize integrated and dynamic trade-oil of the multi-object system of project. Based on analyzing basic principle of dynamic controlling and integrated multi-object trade-off system process, the paper integrated method of cybernetics and network technology, through monitoring on some critical reference points according to the control objects, emphatically discussed the integrated and dynamic multi- object trade-off model and corresponding rules and mechanism in order to realize integration of process management and trade-off of multi-object system.

  15. Flight evaluation of differential GPS aided inertial navigation systems

    NASA Technical Reports Server (NTRS)

    Mcnally, B. David; Paielli, Russell A.; Bach, Ralph E., Jr.; Warner, David N., Jr.

    1992-01-01

    Algorithms are described for integration of Differential Global Positioning System (DGPS) data with Inertial Navigation System (INS) data to provide an integrated DGPS/INS navigation system. The objective is to establish the benefits that can be achieved through various levels of integration of DGPS with INS for precision navigation. An eight state Kalman filter integration was implemented in real-time on a twin turbo-prop transport aircraft to evaluate system performance during terminal approach and landing operations. A fully integrated DGPS/INS system is also presented which models accelerometer and rate-gyro measurement errors plus position, velocity, and attitude errors. The fully integrated system was implemented off-line using range-domain (seventeen-state) and position domain (fifteen-state) Kalman filters. Both filter integration approaches were evaluated using data collected during the flight test. Flight-test data consisted of measurements from a 5 channel Precision Code GPS receiver, a strap-down Inertial Navigation Unit (INU), and GPS satellite differential range corrections from a ground reference station. The aircraft was laser tracked to determine its true position. Results indicate that there is no significant improvement in positioning accuracy with the higher levels of DGPS/INS integration. All three systems provided high-frequency (e.g., 20 Hz) estimates of position and velocity. The fully integrated system provided estimates of inertial sensor errors which may be used to improve INS navigation accuracy should GPS become unavailable, and improved estimates of acceleration, attitude, and body rates which can be used for guidance and control. Precision Code DGPS/INS positioning accuracy (root-mean-square) was 1.0 m cross-track and 3.0 m vertical. (This AGARDograph was sponsored by the Guidance and Control Panel.)

  16. Accelerator-feasible N -body nonlinear integrable system

    DOE PAGES

    Danilov, V.; Nagaitsev, S.

    2014-12-23

    Nonlinear N-body integrable Hamiltonian systems, where N is an arbitrary number, attract the attention of mathematical physicists for the last several decades, following the discovery of some number of these systems. This research presents a new integrable system, which can be realized in facilities such as particle accelerators. This feature makes it more attractive than many of the previous such systems with singular or unphysical forces.

  17. MIUS Integration and Subsystem Test (MIST) data system

    NASA Technical Reports Server (NTRS)

    Pringle, L. M.

    1977-01-01

    A data system for use in testing integrated subsystems of a modular integrated utility system (MIUS) is presented. The MIUS integration and subsystem test (MIST) data system is reviewed from its conception through its checkout and operation as the controlling portion of the MIST facility. The MIST data system provides a real time monitoring and control function that allows for complete evaluation of the performance of the mechanical and electrical subsystems, as well as controls the operation of the various components of the system. In addition to the aforementioned capabilities, the MIST data system provides computerized control of test operations such that minimum manpower is necessary to set up, operate, and shut down subsystems during test periods.

  18. Performance of the Landsat-Data Collection System in a Total System Context

    NASA Technical Reports Server (NTRS)

    Paulson, R. W. (Principal Investigator); Merk, C. F.

    1975-01-01

    The author has identified the following significant results. This experiment was, and continues to be, an integration of the LANDSAT-DCS with the data collection and processing system of the Geological Survey. Although an experimental demonstration, it was a successful integration of a satellite relay system that is capable of continental data collection, and an existing governmental nationwide operational data processing and distributing networks. The Survey's data processing system uses a large general purpose computer with insufficient redundancy for 24-hour a day, 7 day a week operation. This is significant, but soluble obstacle to converting the experimental integration of the system to an operational integration.

  19. Propulsion system/flight control integration for supersonic aircraft

    NASA Technical Reports Server (NTRS)

    Reukauf, P. J.; Burcham, F. W., Jr.

    1976-01-01

    Digital integrated control systems are studied. Such systems allow minimization of undesirable interactions while maximizing performance at all flight conditions. One such program is the YF-12 cooperative control program. The existing analog air data computer, autothrottle, autopilot, and inlet control systems are converted to digital systems by using a general purpose airborne computer and interface unit. Existing control laws are programed and tested in flight. Integrated control laws, derived using accurate mathematical models of the airplane and propulsion system in conjunction with modern control techniques, are tested in flight. Analysis indicates that an integrated autothrottle autopilot gives good flight path control and that observers are used to replace failed sensors.

  20. Computer-aided operations engineering with integrated models of systems and operations

    NASA Technical Reports Server (NTRS)

    Malin, Jane T.; Ryan, Dan; Fleming, Land

    1994-01-01

    CONFIG 3 is a prototype software tool that supports integrated conceptual design evaluation from early in the product life cycle, by supporting isolated or integrated modeling, simulation, and analysis of the function, structure, behavior, failures and operation of system designs. Integration and reuse of models is supported in an object-oriented environment providing capabilities for graph analysis and discrete event simulation. Integration is supported among diverse modeling approaches (component view, configuration or flow path view, and procedure view) and diverse simulation and analysis approaches. Support is provided for integrated engineering in diverse design domains, including mechanical and electro-mechanical systems, distributed computer systems, and chemical processing and transport systems. CONFIG supports abstracted qualitative and symbolic modeling, for early conceptual design. System models are component structure models with operating modes, with embedded time-related behavior models. CONFIG supports failure modeling and modeling of state or configuration changes that result in dynamic changes in dependencies among components. Operations and procedure models are activity structure models that interact with system models. CONFIG is designed to support evaluation of system operability, diagnosability and fault tolerance, and analysis of the development of system effects of problems over time, including faults, failures, and procedural or environmental difficulties.

  1. HIS/BUI: a conceptual model for bottom-up integration of hospital information systems.

    PubMed

    Zviran, M; Armoni, A; Glezer, C

    1998-06-01

    Many successful applications of information systems have been introduced and implemented in hospitals. However, the integration of these applications into a cohesive hospital-wide information system has proved to be more complicated to develop and difficult to accomplish than expected. This paper introduces HIS/BUI, a framework for bottom-up integration of hospital information systems, and demonstrates its application through a real-life case scenario. The scope of the proposed framework is the integration of heterogeneous clinical, administrative, and financial information elements of a hospital into a unified system environment. Under the integrated architecture, all existing local applications are preserved and interconnected to an information hub that serves as a central medical and administrative data warehouse.

  2. Systems Integration Fact Sheet

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    2016-06-01

    This fact sheet is an overview of the Systems Integration subprogram at the U.S. Department of Energy SunShot Initiative. The Systems Integration subprogram enables the widespread deployment of safe, reliable, and cost-effective solar energy technologies by addressing the associated technical and non-technical challenges. These include timely and cost-effective interconnection procedures, optimal system planning, accurate prediction of solar resources, monitoring and control of solar power, maintaining grid reliability and stability, and many more. To address the challenges associated with interconnecting and integrating hundreds of gigawatts of solar power onto the electricity grid, the Systems Integration program funds research, development, and demonstrationmore » projects in four broad, interrelated focus areas: grid performance and reliability, dispatchability, power electronics, and communications.« less

  3. Assessment of the integration capability of system architectures from a complex and distributed software systems perspective

    NASA Astrophysics Data System (ADS)

    Leuchter, S.; Reinert, F.; Müller, W.

    2014-06-01

    Procurement and design of system architectures capable of network centric operations demand for an assessment scheme in order to compare different alternative realizations. In this contribution an assessment method for system architectures targeted at the C4ISR domain is presented. The method addresses the integration capability of software systems from a complex and distributed software system perspective focusing communication, interfaces and software. The aim is to evaluate the capability to integrate a system or its functions within a system-of-systems network. This method uses approaches from software architecture quality assessment and applies them on the system architecture level. It features a specific goal tree of several dimensions that are relevant for enterprise integration. These dimensions have to be weighed against each other and totalized using methods from the normative decision theory in order to reflect the intention of the particular enterprise integration effort. The indicators and measurements for many of the considered quality features rely on a model based view on systems, networks, and the enterprise. That means it is applicable to System-of-System specifications based on enterprise architectural frameworks relying on defined meta-models or domain ontologies for defining views and viewpoints. In the defense context we use the NATO Architecture Framework (NAF) to ground respective system models. The proposed assessment method allows evaluating and comparing competing system designs regarding their future integration potential. It is a contribution to the system-of-systems engineering methodology.

  4. Crew Launch Vehicle (CLV) Avionics and Software Integration Overview

    NASA Technical Reports Server (NTRS)

    Monell, Donald W.; Flynn, Kevin C.; Maroney, Johnny

    2006-01-01

    On January 14, 2004, the President of the United States announced a new plan to explore space and extend a human presence across our solar system. The National Aeronautics and Space Administration (NASA) established the Exploration Systems Mission Directorate (ESMD) to develop and field a Constellation Architecture that will bring the Space Exploration vision to fruition. The Constellation Architecture includes a human-rated Crew Launch Vehicle (CLV) segment, managed by the Marshall Space Flight Center (MSFC), comprised of the First Stage (FS), Upper Stage (US), and Upper Stage Engine (USE) elements. The CLV s purpose is to provide safe and reliable crew and cargo transportation into Low Earth Orbit (LEO), as well as insertion into trans-lunar trajectories. The architecture's Spacecraft segment includes, among other elements, the Crew Exploration Vehicle (CEV), managed by the Johnson Space Flight Center (JSC), which is launched atop the CLV. MSFC is also responsible for CLV and CEV stack integration. This paper provides an overview of the Avionics and Software integration approach (which includes the Integrated System Health Management (ISHM) functions), both within the CLV, and across the CEV interface; it addresses the requirements to be met, logistics of meeting those requirements, and the roles of the various groups. The Avionics Integration and Vehicle Systems Test (ANST) Office was established at the MSFC with system engineering responsibilities for defining and developing the integrated CLV Avionics and Software system. The AIVST Office has defined two Groups, the Avionics and Software Integration Group (AVSIG), and the Integrated System Simulation and Test Integration Group (ISSTIG), and four Panels which will direct trade studies and analyses to ensure the CLV avionics and software meet CLV system and CEV interface requirements. The four panels are: 1) Avionics Integration Panel (AIP), 2) Software Integration Panel, 3) EEE Panel, and 4) Systems Simulation and Test Panel. Membership on the groups and panels includes the MSFC representatives from the requisite engineering disciplines, the First Stage, the Upper Stage, the Upper Stage Engine projects, and key personnel from other NASA centers. The four panels will take the results of trade studies and analyses and develop documentation in support of Design Analysis Cycle Reviews and ultimately the System Requirements Review.

  5. Indicators and measurement tools for health system integration: a knowledge synthesis protocol.

    PubMed

    Oelke, Nelly D; Suter, Esther; da Silva Lima, Maria Alice Dias; Van Vliet-Brown, Cheryl

    2015-07-29

    Health system integration is a key component of health system reform with the goal of improving outcomes for patients, providers, and the health system. Although health systems continue to strive for better integration, current delivery of health services continues to be fragmented. A key gap in the literature is the lack of information on what successful integration looks like and how to measure achievement towards an integrated system. This multi-site study protocol builds on a prior knowledge synthesis completed by two of the primary investigators which identified 10 key principles that collectively support health system integration. The aim is to answer two research questions: What are appropriate indicators for each of the 10 key integration principles developed in our previous knowledge synthesis and what measurement tools are used to measure these indicators? To enhance generalizability of the findings, a partnership between Canada and Brazil was created as health system integration is a priority in both countries and they share similar contexts. This knowledge synthesis will follow an iterative scoping review process with emerging information from knowledge-user engagement leading to the refinement of research questions and study selection. This paper describes the methods for each phase of the study. Research questions were developed with stakeholder input. Indicator identification and prioritization will utilize a modified Delphi method and patient/user focus groups. Based on priority indicators, a search of the literature will be completed and studies screened for inclusion. Quality appraisal of relevant studies will be completed prior to data extraction. Results will be used to develop recommendations and key messages to be presented through integrated and end-of-grant knowledge translation strategies with researchers and knowledge-users from the three jurisdictions. This project will directly benefit policy and decision-makers by providing an easy accessible set of indicators and tools to measure health system integration across different contexts and cultures. Being able to evaluate the success of integration strategies and initiatives will lead to better health system design and improved health outcomes for patients.

  6. Integrated Syntactic/Semantic XML Data Validation with a Reusable Software Component

    ERIC Educational Resources Information Center

    Golikov, Steven

    2013-01-01

    Data integration is a critical component of enterprise system integration, and XML data validation is the foundation for sound data integration of XML-based information systems. Since B2B e-commerce relies on data validation as one of the critical components for enterprise integration, it is imperative for financial industries and e-commerce…

  7. Human Systems Integration in Practice: Constellation Lessons Learned

    NASA Technical Reports Server (NTRS)

    Zumbado, Jennifer Rochlis

    2012-01-01

    NASA's Constellation program provided a unique testbed for Human Systems Integration (HSI) as a fundamental element of the Systems Engineering process. Constellation was the first major program to have HSI mandated by NASA's Human Rating document. Proper HSI is critical to the success of any project that relies on humans to function as operators, maintainers, or controllers of a system. HSI improves mission, system and human performance, significantly reduces lifecycle costs, lowers risk and minimizes re-design. Successful HSI begins with sufficient project schedule dedicated to the generation of human systems requirements, but is by no means solely a requirements management process. A top-down systems engineering process that recognizes throughout the organization, human factors as a technical discipline equal to traditional engineering disciplines with authority for the overall system. This partners with a bottoms-up mechanism for human-centered design and technical issue resolution. The Constellation Human Systems Integration Group (HSIG) was a part of the Systems Engineering and Integration (SE&I) organization within the program office, and existed alongside similar groups such as Flight Performance, Environments & Constraints, and Integrated Loads, Structures and Mechanisms. While the HSIG successfully managed, via influence leadership, a down-and-in Community of Practice to facilitate technical integration and issue resolution, it lacked parallel top-down authority to drive integrated design. This presentation will discuss how HSI was applied to Constellation, the lessons learned and best practices it revealed, and recommendations to future NASA program and project managers. This presentation will discuss how Human Systems Integration (HSI) was applied to NASA's Constellation program, the lessons learned and best practices it revealed, and recommendations to future NASA program and project managers on how to accomplish this critical function.

  8. System integration report

    NASA Technical Reports Server (NTRS)

    Badler, N. I.; Korein, J. D.; Meyer, C.; Manoochehri, K.; Rovins, J.; Beale, J.; Barr, B.

    1985-01-01

    Several areas that arise from the system integration issue were examined. Intersystem analysis is discussed as it relates to software development, shared data bases and interfaces between TEMPUS and PLAID, shaded graphics rendering systems, object design (BUILD), the TEMPUS animation system, anthropometric lab integration, ongoing TEMPUS support and maintenance, and the impact of UNIX and local workstations on the OSDS environment.

  9. Providing an integrated clinical data view in a hospital information system that manages multimedia data.

    PubMed

    Dayhoff, R E; Maloney, D L; Kenney, T J; Fletcher, R D

    1991-01-01

    The VA's hospital information system, the Decentralized Hospital Computer Program (DHCP), is an integrated system based on a powerful set of software tools with shared data accessible from any of its application modules. It includes many functionally specific application subsystems such as laboratory, pharmacy, radiology, and dietetics. Physicians need applications that cross these application boundaries to provide useful and convenient patient data. One of these multi-specialty applications, the DHCP Imaging System, integrates multimedia data to provide clinicians with comprehensive patient-oriented information. User requirements for cross-disciplinary image access can be studied to define needs for similar text data access. Integration approaches must be evaluated both for their ability to deliver patient-oriented text data rapidly and their ability to integrate multimedia data objects. Several potential integration approaches are described as they relate to the DHCP Imaging System.

  10. Providing an integrated clinical data view in a hospital information system that manages multimedia data.

    PubMed Central

    Dayhoff, R. E.; Maloney, D. L.; Kenney, T. J.; Fletcher, R. D.

    1991-01-01

    The VA's hospital information system, the Decentralized Hospital Computer Program (DHCP), is an integrated system based on a powerful set of software tools with shared data accessible from any of its application modules. It includes many functionally specific application subsystems such as laboratory, pharmacy, radiology, and dietetics. Physicians need applications that cross these application boundaries to provide useful and convenient patient data. One of these multi-specialty applications, the DHCP Imaging System, integrates multimedia data to provide clinicians with comprehensive patient-oriented information. User requirements for cross-disciplinary image access can be studied to define needs for similar text data access. Integration approaches must be evaluated both for their ability to deliver patient-oriented text data rapidly and their ability to integrate multimedia data objects. Several potential integration approaches are described as they relate to the DHCP Imaging System. PMID:1807651

  11. Systems Integration | Photovoltaic Research | NREL

    Science.gov Websites

    & Engineering pages: Real-Time PV & Solar Resource Testing Accelerated Testing & Analysis integration support, system-level testing, and systems analysis for the Department of Energy's solar issues and develop solutions for high-penetration grid integration of solar technologies into the

  12. 8. Exterior view, showing tank and associated piping adjacent to ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. Exterior view, showing tank and associated piping adjacent to Test Cell 6, Systems Integration Laboratory Building (T-28), looking south. - Air Force Plant PJKS, Systems Integration Laboratory, Systems Integration Laboratory Building, Waterton Canyon Road & Colorado Highway 121, Lakewood, Jefferson County, CO

  13. Intelligent Insight or Blind Arrogance? The Development of an Integrated Information System.

    ERIC Educational Resources Information Center

    Dubois, Ronald; Freeman, Neil

    1991-01-01

    The first part in a two-part series about the development of an integrated management information system at Chaminade University (Hawaii) discusses decisions made about the system's integration and transportability, modularization, programing language, and productivity in the first five years. (MSE)

  14. 78 FR 63170 - Integrated Postsecondary Education Data System (IPEDS) 2013-2016; Extension of Public Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-23

    ... DEPARTMENT OF EDUCATION Integrated Postsecondary Education Data System (IPEDS) 2013-2016; Extension of Public Comment Period; Correction AGENCY: Department of Education. ACTION: Correction notice... entitled, ``Integrated Postsecondary Education Data System (IPEDS) 2013-2016''. The comment period for this...

  15. ‘Integrative Physiology 2.0’: integration of systems biology into physiology and its application to cardiovascular homeostasis

    PubMed Central

    Kuster, Diederik W D; Merkus, Daphne; van der Velden, Jolanda; Verhoeven, Adrie J M; Duncker, Dirk J

    2011-01-01

    Since the completion of the Human Genome Project and the advent of the large scaled unbiased ‘-omics’ techniques, the field of systems biology has emerged. Systems biology aims to move away from the traditional reductionist molecular approach, which focused on understanding the role of single genes or proteins, towards a more holistic approach by studying networks and interactions between individual components of networks. From a conceptual standpoint, systems biology elicits a ‘back to the future’ experience for any integrative physiologist. However, many of the new techniques and modalities employed by systems biologists yield tremendous potential for integrative physiologists to expand their tool arsenal to (quantitatively) study complex biological processes, such as cardiac remodelling and heart failure, in a truly holistic fashion. We therefore advocate that systems biology should not become/stay a separate discipline with ‘-omics’ as its playing field, but should be integrated into physiology to create ‘Integrative Physiology 2.0’. PMID:21224228

  16. Ceramic Integration Technologies for Advanced Energy Systems: Critical Needs, Technical Challenges, and Opportunities

    NASA Technical Reports Server (NTRS)

    Singh, Mrityunjay

    2010-01-01

    Advanced ceramic integration technologies dramatically impact the energy landscape due to wide scale application of ceramics in all aspects of alternative energy production, storage, distribution, conservation, and efficiency. Examples include fuel cells, thermoelectrics, photovoltaics, gas turbine propulsion systems, distribution and transmission systems based on superconductors, nuclear power generation and waste disposal. Ceramic integration technologies play a key role in fabrication and manufacturing of large and complex shaped parts with multifunctional properties. However, the development of robust and reliable integrated systems with optimum performance requires the understanding of many thermochemical and thermomechanical factors, particularly for high temperature applications. In this presentation, various needs, challenges, and opportunities in design, fabrication, and testing of integrated similar (ceramic ceramic) and dissimilar (ceramic metal) material www.nasa.gov 45 ceramic-ceramic-systems have been discussed. Experimental results for bonding and integration of SiC based Micro-Electro-Mechanical-Systems (MEMS) LDI fuel injector and advanced ceramics and composites for gas turbine applications are presented.

  17. Integrated air revitalization system for Space Station

    NASA Technical Reports Server (NTRS)

    Boyda, R. B.; Miller, C. W.; Schwartz, M. R.

    1986-01-01

    Fifty-one distinct functions are encompassed by the Space Station's Environmental Control and Life Support System; one exception to this noninteractivity of functions is the regenerative air revitalization system that removes and reduces CO2 and generates O2. The integration of these interdependent functions, and of humidity control, into a single system furnishes opportunities for process simplification as well as for power, weight and volume requirement reductions by comparison with discrete subsystems. Attention is presently given to a system which quantifies these integration-related savings and identifies additional advantages that accrue to this integrating design method.

  18. Flat Surface Damage Detection System (FSDDS)

    NASA Technical Reports Server (NTRS)

    Williams, Martha; Lewis, Mark; Gibson, Tracy; Lane, John; Medelius, Pedro; Snyder, Sarah; Ciarlariello, Dan; Parks, Steve; Carrejo, Danny; Rojdev, Kristina

    2013-01-01

    The Flat Surface Damage Detection system (FSDDS} is a sensory system that is capable of detecting impact damages to surfaces utilizing a novel sensor system. This system will provide the ability to monitor the integrity of an inflatable habitat during in situ system health monitoring. The system consists of three main custom designed subsystems: the multi-layer sensing panel, the embedded monitoring system, and the graphical user interface (GUI). The GUI LABVIEW software uses a custom developed damage detection algorithm to determine the damage location based on the sequence of broken sensing lines. It estimates the damage size, the maximum depth, and plots the damage location on a graph. Successfully demonstrated as a stand alone technology during 2011 D-RATS. Software modification also allowed for communication with HDU avionics crew display which was demonstrated remotely (KSC to JSC} during 2012 integration testing. Integrated FSDDS system and stand alone multi-panel systems were demonstrated remotely and at JSC, Mission Operations Test using Space Network Research Federation (SNRF} network in 2012. FY13, FSDDS multi-panel integration with JSC and SNRF network Technology can allow for integration with other complementary damage detection systems.

  19. An integrated knowledge system for wind tunnel testing - Project Engineers' Intelligent Assistant

    NASA Technical Reports Server (NTRS)

    Lo, Ching F.; Shi, George Z.; Hoyt, W. A.; Steinle, Frank W., Jr.

    1993-01-01

    The Project Engineers' Intelligent Assistant (PEIA) is an integrated knowledge system developed using artificial intelligence technology, including hypertext, expert systems, and dynamic user interfaces. This system integrates documents, engineering codes, databases, and knowledge from domain experts into an enriched hypermedia environment and was designed to assist project engineers in planning and conducting wind tunnel tests. PEIA is a modular system which consists of an intelligent user-interface, seven modules and an integrated tool facility. Hypermedia technology is discussed and the seven PEIA modules are described. System maintenance and updating is very easy due to the modular structure and the integrated tool facility provides user access to commercial software shells for documentation, reporting, or database updating. PEIA is expected to provide project engineers with technical information, increase efficiency and productivity, and provide a realistic tool for personnel training.

  20. UAS Integration in the NAS Project: Integrated Test and Evaluation (IT&E) Flight Test 3. Revision E

    NASA Technical Reports Server (NTRS)

    Marston, Michael

    2015-01-01

    The desire and ability to fly Unmanned Aircraft Systems (UAS) in the National Airspace System (NAS) is of increasing urgency. The application of unmanned aircraft to perform national security, defense, scientific, and emergency management are driving the critical need for less restrictive access by UAS to the NAS. UAS represent a new capability that will provide a variety of services in the government (public) and commercial (civil) aviation sectors. The growth of this potential industry has not yet been realized due to the lack of a common understanding of what is required to safely operate UAS in the NAS. NASA's UAS Integration into the NAS Project is conducting research in the areas of Separation Assurance/Sense and Avoid Interoperability, Human Systems Integration (HSI), and Communication to support reducing the barriers of UAS access to the NAS. This research is broken into two research themes namely, UAS Integration and Test Infrastructure. UAS Integration focuses on airspace integration procedures and performance standards to enable UAS integration in the air transportation system, covering Sense and Avoid (SAA) performance standards, command and control performance standards, and human systems integration. The focus of Test Infrastructure is to enable development and validation of airspace integration procedures and performance standards, including the integrated test and evaluation. In support of the integrated test and evaluation efforts, the Project will develop an adaptable, scalable, and schedulable relevant test environment capable of evaluating concepts and technologies for unmanned aircraft systems to safely operate in the NAS. To accomplish this task, the Project will conduct a series of Human-in-the-Loop and Flight Test activities that integrate key concepts, technologies and/or procedures in a relevant air traffic environment. Each of the integrated events will build on the technical achievements, fidelity and complexity of the previous tests and technical simulations, resulting in research findings that support the development of regulations governing the access of UAS into the NAS.

  1. Micro-opto-mechanical devices and systems using epitaxial lift off

    NASA Technical Reports Server (NTRS)

    Camperi-Ginestet, C.; Kim, Young W.; Wilkinson, S.; Allen, M.; Jokerst, N. M.

    1993-01-01

    The integration of high quality, single crystal thin film gallium arsenide (GaAs) and indium phosphide (InP) based photonic and electronic materials and devices with host microstructures fabricated from materials such as silicon (Si), glass, and polymers will enable the fabrication of the next generation of micro-opto-mechanical systems (MOMS) and optoelectronic integrated circuits. Thin film semiconductor devices deposited onto arbitrary host substrates and structures create hybrid (more than one material) near-monolithic integrated systems which can be interconnected electrically using standard inexpensive microfabrication techniques such as vacuum metallization and photolithography. These integrated systems take advantage of the optical and electronic properties of compound semiconductor devices while still using host substrate materials such as silicon, polysilicon, glass and polymers in the microstructures. This type of materials optimization for specific tasks creates higher performance systems than those systems which must use trade-offs in device performance to integrate all of the function in a single material system. The low weight of these thin film devices also makes them attractive for integration with micromechanical devices which may have difficulty supporting and translating the full weight of a standard device. These thin film devices and integrated systems will be attractive for applications, however, only when the development of low cost, high yield fabrication and integration techniques makes their use economically feasible. In this paper, we discuss methods for alignment, selective deposition, and interconnection of thin film epitaxial GaAs and InP based devices onto host substrates and host microstructures.

  2. The integration of quantitative information with an intelligent decision support system for residential energy retrofits

    NASA Astrophysics Data System (ADS)

    Mo, Yunjeong

    The purpose of this research is to support the development of an intelligent Decision Support System (DSS) by integrating quantitative information with expert knowledge in order to facilitate effective retrofit decision-making. To achieve this goal, the Energy Retrofit Decision Process Framework is analyzed. Expert system shell software, a retrofit measure cost database, and energy simulation software are needed for developing the DSS; Exsys Corvid, the NREM database and BEopt were chosen for implementing an integration model. This integration model demonstrates the holistic function of a residential energy retrofit system for existing homes, by providing a prioritized list of retrofit measures with cost information, energy simulation and expert advice. The users, such as homeowners and energy auditors, can acquire all of the necessary retrofit information from this unified system without having to explore several separate systems. The integration model plays the role of a prototype for the finalized intelligent decision support system. It implements all of the necessary functions for the finalized DSS, including integration of the database, energy simulation and expert knowledge.

  3. Nothing Boring About Boron

    PubMed Central

    Pizzorno, Lara

    2015-01-01

    The trace mineral boron is a micronutrient with diverse and vitally important roles in metabolism that render it necessary for plant, animal, and human health, and as recent research suggests, possibly for the evolution of life on Earth. As the current article shows, boron has been proven to be an important trace mineral because it (1) is essential for the growth and maintenance of bone; (2) greatly improves wound healing; (3) beneficially impacts the body’s use of estrogen, testosterone, and vitamin D; (4) boosts magnesium absorption; (5) reduces levels of inflammatory biomarkers, such as high-sensitivity C-reactive protein (hs-CRP) and tumor necrosis factor α (TNF-α); (6) raises levels of antioxidant enzymes, such as superoxide dismutase (SOD), catalase, and glutathione peroxidase; (7) protects against pesticide-induced oxidative stress and heavy-metal toxicity; (8) improves the brains electrical activity, cognitive performance, and short-term memory for elders; (9) influences the formation and activity of key biomolecules, such as S-adenosyl methionine (SAM-e) and nicotinamide adenine dinucleotide (NAD+); (10) has demonstrated preventive and therapeutic effects in a number of cancers, such as prostate, cervical, and lung cancers, and multiple and non-Hodgkin’s lymphoma; and (11) may help ameliorate the adverse effects of traditional chemotherapeutic agents. In none of the numerous studies conducted to date, however, do boron’s beneficial effects appear at intakes > 3 mg/d. No estimated average requirements (EARs) or dietary reference intakes (DRIs) have been set for boron—only an upper intake level (UL) of 20 mg/d for individuals aged ≥ 18 y. The absence of studies showing harm in conjunction with the substantial number of articles showing benefits support the consideration of boron supplementation of 3 mg/d for any individual who is consuming a diet lacking in fruits and vegetables or who is at risk for or has osteopenia; osteoporosis; osteoarthritis (OA); or breast, prostate, or lung cancer. PMID:26770156

  4. Water-extractable magnesium, manganese and copper in leaves and herbs of medicinal plants.

    PubMed

    Konieczyński, Paweł; Wesołowski, Marek

    2012-01-01

    Since herbal teas, infusions and decoctions prepared from medicinal plants are popular remedies, it remains a topical question whether these herbal drugs can be treated as sources of essential elements for humans, who often use them in their everyday diet. Therefore, total and water-extractable contents of Mg, Mn and Cu were determined in 41 leaves originating from four botanical species of Plantago lanceolata, Arctostaphyllos uva-ursi, Rubus fruticosus and Betula sp., as well as in 33 samples of herbs represented by three species of Urtica dioica, Hypericum perforatum and Achillea millefolium. The highest level was determined in the case of Mg (in a range from 2.0 to 7.0 mg/g of dry mass [d.m.]), followed by Mn (from 50.0 to 1300.0 mg/kg d.m.), and lowest of all, Cu (from 3.5 to 19.5 mg/kg d.m.). Student's t-test showed that a statistically significant difference exists between samples originating from different plant species regarding the total content and water-extractable forms of Mg, Mn and Cu. By analysis of the relations between elements, it was observed that total level of Cu correlated with total levels of Mg and Mn, which indicates a synergistic interaction between the essential elements under study. With regard to Dietary Reference Intakes (DRIs), the leaves of Rubus fruticosus contained the highest amounts of a water-extractable bioavailable form of Mn, which guarantees from 160 to 200% of the daily requirement of Mn for women and men, respectively. On the other hand, the extract obtained from Urticae folium gave water-extractable Mg in the amount of 76 mg/500 mL, which constitutes about 20% of daily requirement. The plant material richest in water-extractable Cu was Hyperici herba, containing 154.5 microg/500 mL, or 17% of DRI for both sexes.

  5. The solar UV exposure time required for vitamin D3 synthesis in the human body estimated by numerical simulation and observation in Japan

    NASA Astrophysics Data System (ADS)

    Nakajima, Hideaki; Miyauchi, Masaatsu; Hirai, Chizuko

    2013-04-01

    After the discovery of Antarctic ozone hole, the negative effect of exposure of human body to harmful solar ultraviolet (UV) radiation is widely known. However, there is positive effect of exposure to UV radiation, i.e., vitamin D synthesis. Although the importance of solar UV radiation for vitamin D3 synthesis in the human body is well known, the solar exposure time required to prevent vitamin D deficiency has not been well determined. This study attempted to identify the time of solar exposure required for vitamin D3 synthesis in the body by season, time of day, and geographic location (Sapporo, Tsukuba, and Naha, in Japan) using both numerical simulations and observations. According to the numerical simulation for Tsukuba at noon in July under a cloudless sky, 2.3 min of solar exposure are required to produce 5.5 μg vitamin D3 per 600 cm2 skin. This quantity of vitamin D represents the recommended intake for an adult by the Ministry of Health, Labour and Welfare, and the 2010 Japanese Dietary Reference Intakes (DRIs). In contrast, it took 49.5 min to produce the same amount of vitamin D3 at Sapporo in the northern part of Japan in December, at noon under a cloudless sky. The necessary exposure time varied considerably with the time of the day. For Tsukuba at noon in December, 14.5 min were required, but at 09:00 68.7 min were required and at 15:00 175.8 min were required for the same meteorological conditions. Naha receives high levels of UV radiation allowing vitamin D3 synthesis almost throughout the year. According to our results, we are further developing an index to quantify the necessary time of UV radiation exposure to produce required amount of vitamin D3 from a UV radiation data.

  6. Nothing Boring About Boron.

    PubMed

    Pizzorno, Lara

    2015-08-01

    The trace mineral boron is a micronutrient with diverse and vitally important roles in metabolism that render it necessary for plant, animal, and human health, and as recent research suggests, possibly for the evolution of life on Earth. As the current article shows, boron has been proven to be an important trace mineral because it (1) is essential for the growth and maintenance of bone; (2) greatly improves wound healing; (3) beneficially impacts the body's use of estrogen, testosterone, and vitamin D; (4) boosts magnesium absorption; (5) reduces levels of inflammatory biomarkers, such as high-sensitivity C-reactive protein (hs-CRP) and tumor necrosis factor α (TNF-α); (6) raises levels of antioxidant enzymes, such as superoxide dismutase (SOD), catalase, and glutathione peroxidase; (7) protects against pesticide-induced oxidative stress and heavy-metal toxicity; (8) improves the brains electrical activity, cognitive performance, and short-term memory for elders; (9) influences the formation and activity of key biomolecules, such as S-adenosyl methionine (SAM-e) and nicotinamide adenine dinucleotide (NAD(+)); (10) has demonstrated preventive and therapeutic effects in a number of cancers, such as prostate, cervical, and lung cancers, and multiple and non-Hodgkin's lymphoma; and (11) may help ameliorate the adverse effects of traditional chemotherapeutic agents. In none of the numerous studies conducted to date, however, do boron's beneficial effects appear at intakes > 3 mg/d. No estimated average requirements (EARs) or dietary reference intakes (DRIs) have been set for boron-only an upper intake level (UL) of 20 mg/d for individuals aged ≥ 18 y. The absence of studies showing harm in conjunction with the substantial number of articles showing benefits support the consideration of boron supplementation of 3 mg/d for any individual who is consuming a diet lacking in fruits and vegetables or who is at risk for or has osteopenia; osteoporosis; osteoarthritis (OA); or breast, prostate, or lung cancer.

  7. Dietary protein for athletes: from requirements to metabolic advantage.

    PubMed

    Phillips, Stuart M

    2006-12-01

    The Dietary Reference Intakes (DRI) specify that the requirement for dietary protein for all individuals aged 19 y and older is 0.8 g protein.kg-1.d-1. This Recommended Dietary Allowance (RDA) is cited as adequate for all persons. This amount of protein would be considered by many athletes as the amount to be consumed in a single meal, particularly for strength-training athletes. There does exist, however, published data to suggest that individuals habitually performing resistance and (or) endurance exercise require more protein than their sedentary counterparts. The RDA values for protein are clearly set at "...the level of protein judged to be adequate... to meet the known nutrient needs for practically all healthy people...". The RDA covers protein losses with margins for inter-individual variability and protein quality; the notion of consumption of excess protein above these levels to cover increased needs owing to physical activity is not, however, given any credence. Notwithstanding, diet programs (i.e., energy restriction) espousing the virtue of high protein enjoy continued popularity. A number of well-controlled studies are now published in which "higher" protein diets have been shown to be effective in promoting weight reduction, particularly fat loss. The term "higher" refers to a diet that has people consuming more than the general populations' average intake of approximately 15% of energy from protein, e.g., as much as 30%-35%, which is within an Acceptable Macronutrient Distribution Range (AMDR) as laid out in the DRIs. Of relevance to athletes and those in clinical practice is the fact that higher protein diets have quite consistently been shown to result in greater weight loss, greater fat loss, and preservation of lean mass as compared with "lower" protein diets. A framework for understanding dietary protein intake within the context of weight loss and athletic performance is laid out.

  8. Systems Integration Processes for NASA Ares I Crew Launch Vehicle

    NASA Technical Reports Server (NTRS)

    Taylor, James L.; Reuter, James L.; Sexton, Jeffrey D.

    2006-01-01

    NASA's Exploration Initiative will require development of many new elements to constitute a robust system of systems. New launch vehicles are needed to place cargo and crew in stable Low Earth Orbit (LEO). This paper examines the systems integration processes NASA is utilizing to ensure integration and control of propulsion and nonpropulsion elements within NASA's Crew Launch Vehicle (CLV), now known as the Ares I. The objective of the Ares I is to provide the transportation capabilities to meet the Constellation Program requirements for delivering a Crew Exploration Vehicle (CEV) or other payload to LEO in support of the lunar and Mars missions. The Ares I must successfully provide this capability within cost and schedule, and with an acceptable risk approach. This paper will describe the systems engineering management processes that will be applied to assure Ares I Project success through complete and efficient technical integration. Discussion of technical review and management processes for requirements development and verification, integrated design and analysis, integrated simulation and testing, and the integration of reliability, maintainability and supportability (RMS) into the design will also be included. The Ares I Project is logically divided into elements by the major hardware groupings, and associated management, system engineering, and integration functions. The processes to be described herein are designed to integrate within these Ares I elements and among the other Constellation projects. Also discussed is launch vehicle stack integration (Ares I to CEV, and Ground and Flight Operations integration) throughout the life cycle, including integrated vehicle performance through orbital insertion, recovery of the first stage, and reentry of the upper stage. The processes for decomposing requirements to the elements and ensuring that requirements have been correctly validated, decomposed, and allocated, and that the verification requirements are properly defined to ensure that the system design meets requirements, will be discussed.

  9. System integration test plan for HANDI 2000 business management system

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wilson, D.

    This document presents the system integration test plan for the Commercial-Off-The-Shelf, PassPort and PeopleSoft software, and custom software created to work with the COTS products. The PP software is an integrated application for AP, Contract Management, Inventory Management, Purchasing and Material Safety Data Sheet. The PS software is an integrated application for Project Costing, General Ledger, Human Resources/Training, Payroll, and Base Benefits.

  10. An Overview of the Greyscales Lethality Assessment Methodology

    DTIC Science & Technology

    2011-01-01

    code has already been integrated into the Weapon Systems Division MECA and DUEL missile engagement simulations. It can also be integrated into...incorporated into a variety of simulations. The code has already been integrated into the Weapon Systems Division MECA and DUEL missile engagement...capable of being incorporated into a variety of simulations. The code has already been integrated into the Weapon Systems Division MECA and DUEL missile

  11. Miniaturized GPS/MEMS IMU integrated board

    NASA Technical Reports Server (NTRS)

    Lin, Ching-Fang (Inventor)

    2012-01-01

    This invention documents the efforts on the research and development of a miniaturized GPS/MEMS IMU integrated navigation system. A miniaturized GPS/MEMS IMU integrated navigation system is presented; Laser Dynamic Range Imager (LDRI) based alignment algorithm for space applications is discussed. Two navigation cameras are also included to measure the range and range rate which can be integrated into the GPS/MEMS IMU system to enhance the navigation solution.

  12. UAS-NAS Integrated Human in the Loop: Test Environment Report

    NASA Technical Reports Server (NTRS)

    Murphy, Jim; Otto, Neil; Jovic, Srba

    2015-01-01

    The desire and ability to fly Unmanned Aircraft Systems (UAS) in the National Airspace System (NAS) is of increasing urgency. The application of unmanned aircraft to perform national security, defense, scientific, and emergency management are driving the critical need for less restrictive access by UAS to the NAS. UAS represent a new capability that will provide a variety of services in the government (public) and commercial (civil) aviation sectors. The growth of this potential industry has not yet been realized due to the lack of a common understanding of what is required to safely operate UAS in the NAS. NASA's UAS Integration in the NAS Project is conducting research in the areas of Separation Assurance/Sense and Avoid Interoperability (SSI), Human Systems Integration (HSI), and Communication to support reducing the barriers of UAS access to the NAS. This research was broken into two research themes namely, UAS Integration and Test Infrastructure. UAS Integration focuses on airspace integration procedures and performance standards to enable UAS integration in the air transportation system, covering Sense and Avoid (SAA) performance standards, command and control performance standards, and human systems integration. The focus of the Test Infrastructure theme was to enable development and validation of airspace integration procedures and performance standards, including the execution of integrated test and evaluation. In support of the integrated test and evaluation efforts, the Project developed an adaptable, scalable, and schedulable relevant test environment incorporating live, virtual, and constructive elements capable of validating concepts and technologies for unmanned aircraft systems to safely operate in the NAS. To accomplish this task, the Project planned to conduct three integrated events: a Human-in-the-Loop simulation and two Flight Test series that integrated key concepts, technologies and/or procedures in a relevant air traffic environment. Each of the integrated events were built on the technical achievements, fidelity and complexity of previous simulations and tests, resulting in research findings that support the development of regulations governing the access of UAS into the NAS. The purpose of this document is to describe how well the system under test was representative

  13. Vehicular Integration of Wireless Power Transfer Systems and Hardware Interoperability Case Studies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Onar, Omer C; Campbell, Steven L; Seiber, Larry Eugene

    Several wireless charging methods are under development or available as an aftermarket option in the light-duty automotive market. However, there are not a sufficient number of studies detailing the vehicle integration methods, particularly a complete vehicle integration with higher power levels. This paper presents the design, development, implementation, and vehicle integration of wireless power transfer (WPT)-based electric vehicle (EV) charging systems for various test vehicles. Before having the standards effective, it is expected that WPT technology first will be integrated as an aftermarket retrofitting approach. Inclusion of this technology on production vehicles is contingent upon the release of the internationalmore » standards. The power stages of the system are introduced with the design specifications and control systems including the active front-end rectifier with power factor correction, high frequency power inverter, high frequency isolation transformer, coupling coils, vehicle side full-bridge rectifier and filter, and the vehicle battery. The operating principles of the control, and communications, systems are presented. Aftermarket conversion approaches including the WPT on-board charger (OBC) integration, WPT CHAdeMO integration, and WPT direct battery connection scenarios are described. The experiments are carried out using the integrated vehicles and the results obtained to demonstrate the system performance including the stage-by-stage efficiencies.« less

  14. Architectural approaches for HL7-based health information systems implementation.

    PubMed

    López, D M; Blobel, B

    2010-01-01

    Information systems integration is hard, especially when semantic and business process interoperability requirements need to be met. To succeed, a unified methodology, approaching different aspects of systems architecture such as business, information, computational, engineering and technology viewpoints, has to be considered. The paper contributes with an analysis and demonstration on how the HL7 standard set can support health information systems integration. Based on the Health Information Systems Development Framework (HIS-DF), common architectural models for HIS integration are analyzed. The framework is a standard-based, consistent, comprehensive, customizable, scalable methodology that supports the design of semantically interoperable health information systems and components. Three main architectural models for system integration are analyzed: the point to point interface, the messages server and the mediator models. Point to point interface and messages server models are completely supported by traditional HL7 version 2 and version 3 messaging. The HL7 v3 standard specification, combined with service-oriented, model-driven approaches provided by HIS-DF, makes the mediator model possible. The different integration scenarios are illustrated by describing a proof-of-concept implementation of an integrated public health surveillance system based on Enterprise Java Beans technology. Selecting the appropriate integration architecture is a fundamental issue of any software development project. HIS-DF provides a unique methodological approach guiding the development of healthcare integration projects. The mediator model - offered by the HIS-DF and supported in HL7 v3 artifacts - is the more promising one promoting the development of open, reusable, flexible, semantically interoperable, platform-independent, service-oriented and standard-based health information systems.

  15. Design Reference Missions (DRM): Integrated ODM 'Air-Taxi' Mission Features

    NASA Technical Reports Server (NTRS)

    Kloesel, Kurt; Starr, Ginn; Saltzman, John A.

    2017-01-01

    Design Reference Missions (DRM): Integrated ODM Air-Taxi Mission Features, Hybrid Electric Integrated System Testbed (HEIST) flight control. Structural Health, Energy Storage, Electric Components, Loss of Control, Degraded Systems, System Health, Real-Time IO Operator Geo-Fencing, Regional Noise Abatement and Trusted Autonomy Inter-operability.

  16. An Integrated Library System: Preliminary Considerations.

    ERIC Educational Resources Information Center

    Neroda, Edward

    Noting difficulties experienced by small to medium sized colleges in acquiring integrated library computer systems, this position paper outlines issues related to the subject with the intention of increasing familiarity and interest in integrated library systems. The report includes: a brief review of technological advances as they relate to…

  17. 75 FR 76487 - Haldex Brake Corporation, Commercial Vehicle Systems, Including On-Site Leased Workers of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-08

    ..., Commercial Vehicle Systems, Including On-Site Leased Workers of Johnston Integration Technologies, a... system components. The company reports that workers leased from Johnston Integration Technologies, a... certification to include workers leased from Johnston Integration Technologies, a subsidiary of Johnston...

  18. Integration of Information Retrieval and Database Management Systems.

    ERIC Educational Resources Information Center

    Deogun, Jitender S.; Raghavan, Vijay V.

    1988-01-01

    Discusses the motivation for integrating information retrieval and database management systems, and proposes a probabilistic retrieval model in which records in a file may be composed of attributes (formatted data items) and descriptors (content indicators). The details and resolutions of difficulties involved in integrating such systems are…

  19. 78 FR 16259 - Agency Information Collection Activities; Comment Request; Integrated Postsecondary Education...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-14

    ...; Comment Request; Integrated Postsecondary Education Data System (IPEDS) 2013-2016 AGENCY: National Center... Postsecondary Education Data System (IPEDS) 2013-2016. OMB Control Number: 1850-0582. Type of Review: Revision...,030. Abstract: The Integrated Postsecondary Education Data System (IPEDS) is a web-based data...

  20. Evaluation of Learning Group Approaches for Fostering Integrated Cropping Systems Management

    ERIC Educational Resources Information Center

    Blissett, Hana; Simmons, Steve; Jordan, Nicholas; Nelson, Kristen

    2004-01-01

    Cropping systems management requires integration of multiple forms of knowledge, practice, and learning by farmers, extension educators, and researchers. We evaluated the outcomes of participation in collaborative learning groups organized to address cropping systems and, specifically, challenges of integrated weed management. Groups were…

  1. Integrable nonlinear Schrödinger system on a lattice with three structural elements in the unit cell

    NASA Astrophysics Data System (ADS)

    Vakhnenko, Oleksiy O.

    2018-05-01

    Developing the idea of increasing the number of structural elements in the unit cell of a quasi-one-dimensional lattice as applied to the semi-discrete integrable systems of nonlinear Schrödinger type, we construct the zero-curvature representation for the general integrable nonlinear system on a lattice with three structural elements in the unit cell. The integrability of the obtained general system permits to find explicitly a number of local conservation laws responsible for the main features of system dynamics and in particular for the so-called natural constraints separating the field variables into the basic and the concomitant ones. Thus, considering the reduction to the semi-discrete integrable system of nonlinear Schrödinger type, we revealed the essentially nontrivial impact of concomitant fields on the Poisson structure and on the whole Hamiltonian formulation of system dynamics caused by the nonzero background values of these fields. On the other hand, the zero-curvature representation of a general nonlinear system serves as an indispensable key to the dressing procedure of system integration based upon the Darboux transformation of the auxiliary linear problem and the implicit Bäcklund transformation of field variables. Due to the symmetries inherent to the six-component semi-discrete integrable nonlinear Schrödinger system with attractive-type nonlinearities, the Darboux-Bäcklund dressing scheme is shown to be simplified considerably, giving rise to the appropriately parameterized multi-component soliton solution consisting of six basic and four concomitant components.

  2. Expert systems applications for space shuttle payload integration automation

    NASA Technical Reports Server (NTRS)

    Morris, Keith

    1988-01-01

    Expert systems technologies have been and are continuing to be applied to NASA's Space Shuttle orbiter payload integration problems to provide a level of automation previously unrealizable. NASA's Space Shuttle orbiter was designed to be extremely flexible in its ability to accommodate many different types and combinations of satellites and experiments (payloads) within its payload bay. This flexibility results in differnet and unique engineering resource requirements for each of its payloads, creating recurring payload and cargo integration problems. Expert systems provide a successful solution for these recurring problems. The Orbiter Payload Bay Cabling Expert (EXCABL) was the first expert system, developed to solve the electrical services provisioning problem. A second expert system, EXMATCH, was developed to generate a list of the reusable installation drawings available for each EXCABL solution. These successes have proved the applicability of expert systems technologies to payload integration problems and consequently a third expert system is currently in work. These three expert systems, the manner in which they resolve payload problems and how they will be integrated are described.

  3. Hospital-based chiropractic integration within a large private hospital system in Minnesota: a 10-year example.

    PubMed

    Branson, Richard A

    2009-01-01

    The purpose of this article is to describe a model of chiropractic integration developed over a 10-year period within a private hospital system in Minnesota. Needs were assessed by surveying attitudes and behaviors related to chiropractic and complementary and alternative medicine (CAM) of physicians associated with the hospital. Analyzing referral and utilization patterns assessed chiropractic integration into the hospital system. One hundred five surveys were returned after 2 mailings for a response rate of 74%. Seventy-four percent of respondents supported integration of CAM into the hospital system, although 45% supported the primary care physician as the gatekeeper for CAM use. From 2006 to 2008, there were 8294 unique new patients in the chiropractic program. Primary care providers (medical doctors and physician assistants) were the most common referral source, followed by self-referred patients, sports medicine physicians, and orthopedic physicians. Overall examination of the program identified that facilitators of chiropractic integration were (1) growth in interest in CAM, (2) establishing relationships with key administrators and providers, (3) use of evidence-based practice, (4) adequate physical space, and (5) creation of an integrated spine care program. Barriers were (1) lack of understanding of chiropractic professional identity by certain providers and (2) certain financial aspects of third-party payment for chiropractic. This article describes the process of integrating chiropractic into one of the largest private hospital systems in Minnesota from a business and professional perspective and the results achieved once chiropractic was integrated into the system. This study identified key factors that facilitated integration of services and demonstrates that chiropractic care can be successfully integrated within a hospital system.

  4. ESIF Call for High-Impact Integrated Projects | Energy Systems Integration

    Science.gov Websites

    Integrated Projects As a U.S. Department of Energy user facility, the Energy Systems Integration Facility concepts, tools, and technologies needed to measure, analyze, predict, protect, and control the grid of the Facility | NREL ESIF Call for High-Impact Integrated Projects ESIF Call for High-Impact

  5. Simultaneous and Sequential Integration by Cre/loxP Site-Specific Recombination in Saccharomyces cerevisiae.

    PubMed

    Choi, Ho-Jung; Kim, Yeon-Hee

    2018-05-28

    A Cre/ loxP -δ-integration system was developed to allow sequential and simultaneous integration of a multiple gene expression cassette in Saccharomyces cerevisiae . To allow repeated integrations, the reusable Candida glabrata MARKER ( CgMARKER ) carrying loxP sequences was used, and the integrated CgMARKER was efficiently removed by inducing Cre recombinase. The XYLP and XYLB genes encoding endoxylanase and β-xylosidase, respectively, were used as model genes for xylan metabolism in this system, and the copy number of these genes was increased to 15.8 and 16.9 copies/cell, respectively, by repeated integration. This integration system is a promising approach for the easy construction of yeast strains with enhanced metabolic pathways through multicopy gene expression.

  6. Coordinated Research in Robotics and Integrated Manufacturing.

    DTIC Science & Technology

    1983-07-31

    of three research divisions: Robot Systems, Management Systems, and Integrated Design and Manufacturing, and involves about 40 faculty spanning the...keystone of their program. A relatively smaller level of effort is being supported within the Management Systems Division. This is the first annual...SYSTEMS MANAGEMENT 0 DESIGN DATABASES " ROBOT-BASED 0 HUMAN FACTORSMANUFACTURING • CAD CELL* PRODUCTIONMUCR LANNING * INTEGRATION LANGUAGE AND VIA LOCAL

  7. Energy Systems Integration Facility Insight Center | Energy Systems

    Science.gov Websites

    simulation data. Photo of researchers studying data on a 3-D power system profile depicting the interaction of renewable energy resources on the grid. Capabilities The Insight Center offers the following Integration Facility Insight Center Located adjacent to the Energy System Integration Facility's High

  8. Integrated management of depression: improving system quality and creating effective interfaces.

    PubMed

    Myette, Thomas L

    2008-04-01

    Depression is a chronic recurrent condition and is a leading cause of work disability. Improving occupational outcomes for depression will require an integrated approach that incorporates best practices from the clinical, community, and workplace systems. This article briefly reviews recent quality improvement initiatives and promising practices in each system and then shifts to the importance of systems integration. An integrated chronic care model uses a sophisticated case management process to support essential relationships, facilitate key plans, and efficiently link the three systems to optimize clinical, economic, and occupational outcomes. An expanded role for employers and their agents in the management of depression and other chronic diseases is seen as fundamental to maintaining a healthy and productive workforce. To improve occupational outcomes for depression by integrating best practices from the clinical, community, and workplace systems. After a brief review of quality improvement initiatives and promising practices in each system, an integrated chronic care model is introduced. A case management process that links critical systems, supports essential relationships, and facilitates key plans is expected to result in improvements in clinical, economic, and occupational outcomes. Employers should be more engaged with clinical and community partners in the prevention and control of depression in affected employees.

  9. Home birth integration into the health care systems of eleven international jurisdictions.

    PubMed

    Comeau, Amanda; Hutton, Eileen K; Simioni, Julia; Anvari, Ella; Bowen, Megan; Kruegar, Samantha; Darling, Elizabeth K

    2018-02-13

    The purpose of this study was to develop assessment criteria that could be used to examine the level of integration of home birth within larger health care systems in developed countries across 11 international jurisdictions. An expert panel developed criteria and a definition to assess home birth integration within health care systems. We selected jurisdictions based on the publications that were eligible for inclusion in our systematic review and meta-analysis on planned place of birth. We sent the authors of the included publications a questionnaire about home birth practitioners and practices in their respective health care system at the time of their studies. We searched published peer-reviewed, non-peer-reviewed, and gray literature, and the websites of professional bodies to document information about home birth integration in each jurisdiction based on our criteria. Where information was lacking, we contacted experts in the field from the relevant jurisdiction. Home birth is well integrated into the health care system in British Columbia (Canada), England, Iceland, the Netherlands, New Zealand, Ontario (Canada), and Washington State (USA). Home birth is less well integrated into the health care system in Australia, Japan, Norway, and Sweden. This paper is the first to propose criteria for the evaluation of home birth integration within larger maternity care systems. Application of these criteria across 11 international jurisdictions indicates differences in the recognition and training of home birth practitioners, in access to hospital facilities, and in the supplies and equipment available at home births, which give rise to variation in the level of integration across different settings. Standardized criteria for the evaluation of systems integration are essential for interpreting planned home birth outcomes that emerge from contextual differences. © 2018 Wiley Periodicals, Inc.

  10. Integration Science and Technology of Advanced Ceramics for Energy and Environmental Applications

    NASA Technical Reports Server (NTRS)

    Singh, M.

    2012-01-01

    The discovery of new and innovative materials has been known to culminate in major turning points in human history. The transformative impact and functional manifestation of new materials have been demonstrated in every historical era by their integration into new products, systems, assemblies, and devices. In modern times, the integration of new materials into usable products has a special relevance for the technological development and economic competitiveness of industrial societies. Advanced ceramic technologies dramatically impact the energy and environmental landscape due to potential wide scale applications in all aspects of energy production, storage, distribution, conservation, and efficiency. Examples include gas turbine propulsion systems, fuel cells, thermoelectrics, photovoltaics, distribution and transmission systems based on superconductors, nuclear power generation, and waste disposal. Robust ceramic integration technologies enable hierarchical design and manufacturing of intricate ceramic components starting with geometrically simpler units that are subsequently joined to themselves and/or to metals to create components with progressively higher levels of complexity and functionality. However, for the development of robust and reliable integrated systems with optimum performance under different operating conditions, the detailed understanding of various thermochemical and thermomechanical factors is critical. Different approaches are required for the integration of ceramic-metal and ceramic-ceramic systems across length scales (macro to nano). In this presentation, a few examples of integration of ceramic to metals and ceramic to ceramic systems will be presented. Various challenges and opportunities in design, fabrication, and testing of integrated similar (ceramic-ceramic) and dissimilar (ceramic-metal) material systems will be discussed. Potential opportunities and need for the development of innovative design philosophies, approaches, and integrated system testing under simulated application conditions will also be presented.

  11. 6. Exterior view, showing structural details and instrumentation at the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Exterior view, showing structural details and instrumentation at the walk-in entry level (bottom) of Test Cell 6, Systems Integration Laboratory Building (T-28), looking southwest. - Air Force Plant PJKS, Systems Integration Laboratory, Systems Integration Laboratory Building, Waterton Canyon Road & Colorado Highway 121, Lakewood, Jefferson County, CO

  12. 7. Exterior view, showing instrumentation and gauge panel at the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Exterior view, showing instrumentation and gauge panel at the walk-in entry level (bottom) of Test Cell 6, Systems Integration Laboratory Building (T-28), looking west. - Air Force Plant PJKS, Systems Integration Laboratory, Systems Integration Laboratory Building, Waterton Canyon Road & Colorado Highway 121, Lakewood, Jefferson County, CO

  13. 40 CFR 86.1821-01 - Evaporative/refueling family determination.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., construction and materials. (3) Fuel system. (4) Type of refueling emission control system—non-integrated or integrated with the evaporative control system. Further, if the system is non-integrated, whether or not any... equivalent component durability over the vehicle's useful life; and (3) Evidence that the groups will result...

  14. 40 CFR 86.1821-01 - Evaporative/refueling family determination.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., construction and materials. (3) Fuel system. (4) Type of refueling emission control system—non-integrated or integrated with the evaporative control system. Further, if the system is non-integrated, whether or not any... equivalent component durability over the vehicle's useful life; and (3) Evidence that the groups will result...

  15. 40 CFR 86.1821-01 - Evaporative/refueling family determination.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., construction and materials. (3) Fuel system. (4) Type of refueling emission control system—non-integrated or integrated with the evaporative control system. Further, if the system is non-integrated, whether or not any... equivalent component durability over the vehicle's useful life; and (3) Evidence that the groups will result...

  16. 40 CFR 86.1821-01 - Evaporative/refueling family determination.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., construction and materials. (3) Fuel system. (4) Type of refueling emission control system—non-integrated or integrated with the evaporative control system. Further, if the system is non-integrated, whether or not any... equivalent component durability over the vehicle's useful life; and (3) Evidence that the groups will result...

  17. Oculometric Screening for Traumatic Brain Injury in Veterans

    DTIC Science & Technology

    2017-06-01

    Durso, F., & Lee, J. (2015). APA handbook of human systems integration . Washington, DC: The American Psychological Association. Brain Injury Association...Submitted in partial fulfillment of the requirements for the degree of MASTER OF SCIENCE IN HUMAN SYSTEMS INTEGRATION from the NAVAL POSTGRADUATE...PURPOSE ...................................................................................................3 C. HUMAN SYSTEMS INTEGRATION CONSIDERATIONS

  18. 77 FR 39736 - Certain Integrated Solar Power Systems and Components Thereof; Notice of Termination of the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-05

    ... certain integrated solar power systems and components thereof by reason of infringement of certain claims... INTERNATIONAL TRADE COMMISSION [Investigation No. 337-TA-811] Certain Integrated Solar Power Systems and Components Thereof; Notice of Termination of the Investigation Based on Settlement AGENCY: U.S...

  19. 10. Exterior view, showing the structural details and tanks above ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. Exterior view, showing the structural details and tanks above at walk-in entry level (bottom) of Test Cell 7, Systems Integration Laboratory Building (T-28), looking west. - Air Force Plant PJKS, Systems Integration Laboratory, Systems Integration Laboratory Building, Waterton Canyon Road & Colorado Highway 121, Lakewood, Jefferson County, CO

  20. 77 FR 9226 - Physical Systems Integration, LLC; Supplemental Notice That Initial Market-Based Rate Filing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-16

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. ER12-1013-000] Physical Systems Integration, LLC; Supplemental Notice That Initial Market-Based Rate Filing Includes Request for... Physical Systems Integration, LLC's application for market-based rate authority, with an accompanying rate...

  1. Energy Systems Integration Facility Overview

    ScienceCinema

    Arvizu, Dan; Chistensen, Dana; Hannegan, Bryan; Garret, Bobi; Kroposki, Ben; Symko-Davies, Martha; Post, David; Hammond, Steve; Kutscher, Chuck; Wipke, Keith

    2018-01-16

    The U.S. Department of Energy's Energy Systems Integration Facility (ESIF) is located at the National Renewable Energy Laboratory is the right tool, at the right time... a first-of-its-kind facility that addresses the challenges of large-scale integration of clean energy technologies into the energy systems that power the nation.

  2. Energy Systems Integration News | Energy Systems Integration Facility |

    Science.gov Websites

    for its novel approach to energy reduction. The ultra-efficient ESIF data center features a chiller "chips to bricks" approach to sustainability integrates the data center into the facility systems, rather than trying to optimize each in isolation. Key to the approach was collaboration with

  3. Integrating SAP to Information Systems Curriculum: Design and Delivery

    ERIC Educational Resources Information Center

    Wang, Ming

    2011-01-01

    Information Systems (IS) education is being transformed from the segmented applications toward the integrated enterprise-wide system software Enterprise Resource Planning (ERP). ERP is a platform that integrates all business functions with its centralized data repository shared by all the business operations in the enterprise. This tremendous…

  4. Coast guard : as deepwater systems integrator, coast guard Is reassessing costs and capabilities but lags in applying its disciplined acquisition approach.

    DOT National Transportation Integrated Search

    2009-07-01

    The Deepwater Program includes efforts to build or modernize ships and aircraft and to procure other capabilities. In 2002, the Coast Guard contracted with Integrated Coast Guard Systems (ICGS) to manage the acquisition as systems integrator. After a...

  5. Academic Research Integration System

    ERIC Educational Resources Information Center

    Surugiu, Iula; Velicano, Manole

    2008-01-01

    This paper comprises results concluding the research activity done so far regarding enhanced web services and system integration. The objective of the paper is to define the software architecture for a coherent framework and methodology for enhancing existing web services into an integrated system. This document presents the research work that has…

  6. Lack of integration governance in ERP development: a case study on causes and effects

    NASA Astrophysics Data System (ADS)

    Kähkönen, Tommi; Smolander, Kari; Maglyas, Andrey

    2017-09-01

    The development of an enterprise resource planning (ERP) system starts actually after it has been implemented and taken into use. It is necessary to integrate ERP with other business information systems inside and outside the company. With the grounded theory, we aim to understand how integration challenges emerged in a large manufacturing enterprise when the long-term ERP system reached the beginning of its retirement. Structural changes, an information technology governance model, lack of organisational vision, having no architectural descriptions, lack of collaboration, cost cutting, and organisational culture made integration governance troublesome. As a consequence, the enterprise suffered from several undesired effects, such as complex integration scenarios between internal systems, and failing to provide its customers the needed information. The reduction of costs strengthened the organisational silos further and led to unrealised business process improvements. We provide practitioners with four recommendations. First, the organisational goals for integration should be exposed. Second, when evaluating the needs and impacts of integration, a documented architectural description about the system landscape needs to be utilised. Third, the role of IT should be emphasised in development decision-making, and fourth, collaboration is the core ingredient for successful integration governance.

  7. On the integration of a class of nonlinear systems of ordinary differential equations

    NASA Astrophysics Data System (ADS)

    Talyshev, Aleksandr A.

    2017-11-01

    For each associative, commutative, and unitary algebra over the field of real or complex numbers and an integrable nonlinear ordinary differential equation we can to construct integrable systems of ordinary differential equations and integrable systems of partial differential equations. In this paper we consider in some sense the inverse problem. Determine the conditions under which a given system of ordinary differential equations can be represented as a differential equation in some associative, commutative and unitary algebra. It is also shown that associativity is not a necessary condition.

  8. Stateless and stateful implementations of faithful execution

    DOEpatents

    Pierson, Lyndon G; Witzke, Edward L; Tarman, Thomas D; Robertson, Perry J; Eldridge, John M; Campbell, Philip L

    2014-12-16

    A faithful execution system includes system memory, a target processor, and protection engine. The system memory stores a ciphertext including value fields and integrity fields. The value fields each include an encrypted executable instruction and the integrity fields each include an encrypted integrity value for determining whether a corresponding one of the value fields has been modified. The target processor executes plaintext instructions decoded from the ciphertext while the protection engine is coupled between the system memory and the target processor. The protection engine includes logic to retrieve the ciphertext from the system memory, decrypt the value fields into the plaintext instructions, perform an integrity check based on the integrity fields to determine whether any of the corresponding value fields have been modified, and provide the plaintext instructions to the target processor for execution.

  9. A web-enabled system for integrated assessment of watershed development

    USGS Publications Warehouse

    Dymond, R.; Lohani, V.; Regmi, B.; Dietz, R.

    2004-01-01

    Researchers at Virginia Tech have put together the primary structure of a web enabled integrated modeling system that has potential to be a planning tool to help decision makers and stakeholders in making appropriate watershed management decisions. This paper describes the integrated system, including data sources, collection, analysis methods, system software and design, and issues of integrating the various component models. The integrated system has three modeling components, namely hydrology, economics, and fish health, and is accompanied by descriptive 'help files.' Since all three components have a related spatial aspect, GIS technology provides the integration platform. When completed, a user will access the integrated system over the web to choose pre-selected land development patterns to create a 'what if' scenario using an easy-to-follow interface. The hydrologic model simulates effects of the scenario on annual runoff volume, flood peaks of various return periods, and ground water recharge. The economics model evaluates tax revenue and fiscal costs as a result of a new land development scenario. The fish health model evaluates effects of new land uses in zones of influence to the health of fish populations in those areas. Copyright ASCE 2004.

  10. A Concept of Operations for an Integrated Vehicle Health Assurance System

    NASA Technical Reports Server (NTRS)

    Hunter, Gary W.; Ross, Richard W.; Berger, David E.; Lekki, John D.; Mah, Robert W.; Perey, Danie F.; Schuet, Stefan R.; Simon, Donald L.; Smith, Stephen W.

    2013-01-01

    This document describes a Concept of Operations (ConOps) for an Integrated Vehicle Health Assurance System (IVHAS). This ConOps is associated with the Maintain Vehicle Safety (MVS) between Major Inspections Technical Challenge in the Vehicle Systems Safety Technologies (VSST) Project within NASA s Aviation Safety Program. In particular, this document seeks to describe an integrated system concept for vehicle health assurance that integrates ground-based inspection and repair information with in-flight measurement data for airframe, propulsion, and avionics subsystems. The MVS Technical Challenge intends to maintain vehicle safety between major inspections by developing and demonstrating new integrated health management and failure prevention technologies to assure the integrity of vehicle systems between major inspection intervals and maintain vehicle state awareness during flight. The approach provided by this ConOps is intended to help optimize technology selection and development, as well as allow the initial integration and demonstration of these subsystem technologies over the 5 year span of the VSST program, and serve as a guideline for developing IVHAS technologies under the Aviation Safety Program within the next 5 to 15 years. A long-term vision of IVHAS is provided to describe a basic roadmap for more intelligent and autonomous vehicle systems.

  11. Integrating national community-based health worker programmes into health systems: a systematic review identifying lessons learned from low-and middle-income countries.

    PubMed

    Zulu, Joseph Mumba; Kinsman, John; Michelo, Charles; Hurtig, Anna-Karin

    2014-09-22

    Despite the development of national community-based health worker (CBHW) programmes in several low- and middle-income countries, their integration into health systems has not been optimal. Studies have been conducted to investigate the factors influencing the integration processes, but systematic reviews to provide a more comprehensive understanding are lacking. We conducted a systematic review of published research to understand factors that may influence the integration of national CBHW programmes into health systems in low- and middle-income countries. To be included in the study, CBHW programmes should have been developed by the government and have standardised training, supervision and incentive structures. A conceptual framework on the integration of health innovations into health systems guided the review. We identified 3410 records, of which 36 were finally selected, and on which an analysis was conducted concerning the themes and pathways associated with different factors that may influence the integration process. Four programmes from Brazil, Ethiopia, India and Pakistan met the inclusion criteria. Different aspects of each of these programmes were integrated in different ways into their respective health systems. Factors that facilitated the integration process included the magnitude of countries' human resources for health problems and the associated discourses about how to address these problems; the perceived relative advantage of national CBHWs with regard to delivering health services over training and retaining highly skilled health workers; and the participation of some politicians and community members in programme processes, with the result that they viewed the programmes as legitimate, credible and relevant. Finally, integration of programmes within the existing health systems enhanced programme compatibility with the health systems' governance, financing and training functions. Factors that inhibited the integration process included a rapid scale-up process; resistance from other health workers; discrimination of CBHWs based on social, gender and economic status; ineffective incentive structures; inadequate infrastructure and supplies; and hierarchical and parallel communication structures. CBHW programmes should design their scale-up strategy differently based on current contextual factors. Further, adoption of a stepwise approach to the scale-up and integration process may positively shape the integration process of CBHW programmes into health systems.

  12. Integrated Speed Limiter and Fatigue Analyzer System

    NASA Astrophysics Data System (ADS)

    Pranoto, Hadi; Leman, A. M.; Wahab, Abdi; Sebayang, Darwin

    2018-03-01

    The traffic accident increase in line with the growth of the vehicle, so the safety system must be developed to decrease the accident. This paper will purpose the integrated between speed limiter and fatigue analyser to improve the safety for vehicle, and also to analyse if there is an accident. The device and the software or application are developed and then integrated into one system. The testing held to prove the integrated between device and the application, and it show the system can work well. The next improvement for this system can be developing the server to collect data from internet, so the driver and the vehicle owner can monitor the system by internet.

  13. Upon Generating Discrete Expanding Integrable Models of the Toda Lattice Systems and Infinite Conservation Laws

    NASA Astrophysics Data System (ADS)

    Zhang, Yufeng; Zhang, Xiangzhi; Wang, Yan; Liu, Jiangen

    2017-01-01

    With the help of R-matrix approach, we present the Toda lattice systems that have extensive applications in statistical physics and quantum physics. By constructing a new discrete integrable formula by R-matrix, the discrete expanding integrable models of the Toda lattice systems and their Lax pairs are generated, respectively. By following the constructing formula again, we obtain the corresponding (2+1)-dimensional Toda lattice systems and their Lax pairs, as well as their (2+1)-dimensional discrete expanding integrable models. Finally, some conservation laws of a (1+1)-dimensional generalised Toda lattice system and a new (2+1)-dimensional lattice system are generated, respectively.

  14. Design of the Hospital Integrated Information Management System Based on Cloud Platform.

    PubMed

    Aijing, L; Jin, Y

    2015-12-01

    At present, the outdated information management style cannot meet the needs of hospital management, and has become the bottleneck of hospital's management and development. In order to improve the integrated management of information, hospitals have increased their investment in integrated information management systems. On account of the lack of reasonable and scientific design, some hospital integrated information management systems have common problems, such as unfriendly interface, poor portability and maintainability, low security and efficiency, lack of interactivity and information sharing. To solve the problem, this paper carries out the research and design of a hospital information management system based on cloud platform, which can realize the optimized integration of hospital information resources and save money.

  15. [Integrated delivery systems in California--success and failure determining factors for the first 10 years and impetus for Germany].

    PubMed

    Janus, K; Amelung, V E

    2004-10-01

    Since the coming into effect of the Health Care Modernization Act (Gesundheitsmodernisierungsgesetz) the conditions for integrated health care delivery are favourable in Germany. However, comprehensive approaches are a long time in coming. In contrast, integrated health care delivery as an integral part of the spreading of managed care entered a further stage of development, which enables health care decision makers to draw conclusions regarding the further development of integrated health care delivery in Germany. Based on case studies integrated delivery systems in the San Francisco Bay Area have been analyzed with the objective to evaluate pitfalls and successful strategies for integrated health care delivery. The major pitfalls refer to an insufficient local focus, a lack of actual integration and the application of per capita reimbursement (which is a key subject on the political agenda in Germany as well) within integrated delivery systems. On the contrary, successful strategies include achieving a dynamic tension between centralized and decentralized coordination, internal and external relationship management, well organised human resource management including a well-defined corporate policy and a comprehensive implementation of information technology. Based on US experiences with integrated delivery systems implications for the design of integrated health care delivery in Germany are discussed.

  16. Integrated Vehicle Thermal Management for Advanced Vehicle Propulsion Technologies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bennion, K.; Thornton, M.

    A critical element to the success of new propulsion technologies that enable reductions in fuel use is the integration of component thermal management technologies within a viable vehicle package. Vehicle operation requires vehicle thermal management systems capable of balancing the needs of multiple vehicle systems that may require heat for operation, require cooling to reject heat, or require operation within specified temperature ranges. As vehicle propulsion transitions away from a single form of vehicle propulsion based solely on conventional internal combustion engines (ICEs) toward a wider array of choices including more electrically dominant systems such as plug-in hybrid electric vehiclesmore » (PHEVs), new challenges arise associated with vehicle thermal management. As the number of components that require active thermal management increase, so do the costs in terms of dollars, weight, and size. Integrated vehicle thermal management is one pathway to address the cost, weight, and size challenges. The integration of the power electronics and electric machine (PEEM) thermal management with other existing vehicle systems is one path for reducing the cost of electric drive systems. This work demonstrates techniques for evaluating and quantifying the integrated transient and continuous heat loads of combined systems incorporating electric drive systems that operate primarily under transient duty cycles, but the approach can be extended to include additional steady-state duty cycles typical for designing vehicle thermal management systems of conventional vehicles. The work compares opportunities to create an integrated low temperature coolant loop combining the power electronics and electric machine with the air conditioning system in contrast to a high temperature system integrated with the ICE cooling system.« less

  17. NASA Human Integration Design Handbook (HIDH): Revitalization of Space-Related Human Factors, Environmental, and Habitability Data and Design Guidance

    NASA Technical Reports Server (NTRS)

    Stroud, Kenneth; Pickett, Lynn; Tillman, Barry

    2008-01-01

    This poster presentation reviews the Human Integration Design Handbook (HIDH). It provides guidance and data to aid vehicle / habitat designers in human-system integration It also aids requirements writers in development of human-system integration requirements from SFHSS Standards

  18. NREL Leads Energy Systems Integration - Continuum Magazine | NREL

    Science.gov Websites

    performance data to manage and optimize campus energy use. Integrated Solutions for a Complex Energy World 03 Integrated Solutions for a Complex Energy World Energy systems integration optimizes the design and efficient data centers in the world. Sustainability through Dynamic Energy Management Sustainability through

  19. Intelligent multi-sensor integrations

    NASA Technical Reports Server (NTRS)

    Volz, Richard A.; Jain, Ramesh; Weymouth, Terry

    1989-01-01

    Growth in the intelligence of space systems requires the use and integration of data from multiple sensors. Generic tools are being developed for extracting and integrating information obtained from multiple sources. The full spectrum is addressed for issues ranging from data acquisition, to characterization of sensor data, to adaptive systems for utilizing the data. In particular, there are three major aspects to the project, multisensor processing, an adaptive approach to object recognition, and distributed sensor system integration.

  20. Integrated Test and Evaluation Flight Test 3 Flight Test Plan

    NASA Technical Reports Server (NTRS)

    Marston, Michael Lawrence

    2015-01-01

    The desire and ability to fly Unmanned Aircraft Systems (UAS) in the National Airspace System (NAS) is of increasing urgency. The application of unmanned aircraft to perform national security, defense, scientific, and emergency management are driving the critical need for less restrictive access by UAS to the NAS. UAS represent a new capability that will provide a variety of services in the government (public) and commercial (civil) aviation sectors. The growth of this potential industry has not yet been realized due to the lack of a common understanding of what is required to safely operate UAS in the NAS. NASA's UAS Integration into the NAS Project is conducting research in the areas of Separation Assurance/Sense and Avoid Interoperability, Human Systems Integration (HSI), and Communication to support reducing the barriers of UAS access to the NAS. This research is broken into two research themes namely, UAS Integration and Test Infrastructure. UAS Integration focuses on airspace integration procedures and performance standards to enable UAS integration in the air transportation system, covering Sense and Avoid (SAA) performance standards, command and control performance standards, and human systems integration. The focus of Test Infrastructure is to enable development and validation of airspace integration procedures and performance standards, including the integrated test and evaluation. In support of the integrated test and evaluation efforts, the Project will develop an adaptable, scalable, and schedulable relevant test environment capable of evaluating concepts and technologies for unmanned aircraft systems to safely operate in the NAS. To accomplish this task, the Project will conduct a series of Human-in-the-Loop and Flight Test activities that integrate key concepts, technologies and/or procedures in a relevant air traffic environment. Each of the integrated events will build on the technical achievements, fidelity and complexity of the previous tests and technical simulations, resulting in research findings that support the development of regulations governing the access of UAS into the NAS.

  1. Development of a condenser for the dual catalyst water recovery system

    NASA Technical Reports Server (NTRS)

    Budinikas, P.; Rasouli, F.; Rabadi, N.

    1983-01-01

    Conceptual evaporation/condensation systems suitable for integration with the catalytic water recovery method were evaluated. The primary requirements for each concept were its capability to operate under zero-gravity conditions, condense recovered water from a vapor-noncondensable gas mixture, and integrate with the catalytic system. Specific energy requirements were estimated for concepts meeting the primary requirements, and the concept most suitable for integration with the catalytic system was proposed. A three-man rate condenser capable of integration with the proposed system, condensing water vapor in presence of noncondensables and transferring the heat of condensation to feed urine was designed, fabricated, and tested. It was treated with steam/air mixtures at atmospheric and elevated pressures and integrated with an actual catalytic water recovery system. The condenser has a condensation efficiency exceeding 90% and heat transfer rate of approximately 85% of theoretical value at coolant temperature ranging from 7 to 80 deg C.

  2. Ver-i-Fus: an integrated access control and information monitoring and management system

    NASA Astrophysics Data System (ADS)

    Thomopoulos, Stelios C.; Reisman, James G.; Papelis, Yiannis E.

    1997-01-01

    This paper describes the Ver-i-Fus Integrated Access Control and Information Monitoring and Management (IAC-I2M) system that INTELNET Inc. has developed. The Ver-i-Fus IAC-I2M system has been designed to meet the most stringent security and information monitoring requirements while allowing two- way communication between the user and the system. The systems offers a flexible interface that permits to integrate practically any sensing device, or combination of sensing devices, including a live-scan fingerprint reader, thus providing biometrics verification for enhanced security. Different configurations of the system provide solutions to different sets of access control problems. The re-configurable hardware interface, tied together with biometrics verification and a flexible interface that allows to integrate Ver-i-Fus with an MIS, provide an integrated solution to security, time and attendance, labor monitoring, production monitoring, and payroll applications.

  3. Relational systems change: implementing a model of change in integrating services for women with substance abuse and mental health disorders and histories of trauma.

    PubMed

    Markoff, Laurie S; Finkelstein, Norma; Kammerer, Nina; Kreiner, Peter; Prost, Carol A

    2005-01-01

    This article describes the "relational systems change" model developed by the Institute for Health and Recovery, and the implementation of the model in Massachusetts from 1998-2002 to facilitate systems change to support the delivery of integrated and trauma-informed services for women with co-occurring substance abuse and mental health disorders and histories of violence and empirical evidence of resulting systems changes. The federally funded Women Embracing Life and Living (WELL) Project utilized relational strategies to facilitate systems change within and across 3 systems levels: local treatment providers, community (or region), and state. The WELL Project demonstrates that a highly collaborative, inclusive, and facilitated change process can effect services integration within agencies (intra-agency), strengthen integration within a regional network of agencies (interagency), and foster state support for services integration.

  4. Integrating CLIPS applications into heterogeneous distributed systems

    NASA Technical Reports Server (NTRS)

    Adler, Richard M.

    1991-01-01

    SOCIAL is an advanced, object-oriented development tool for integrating intelligent and conventional applications across heterogeneous hardware and software platforms. SOCIAL defines a family of 'wrapper' objects called agents, which incorporate predefined capabilities for distributed communication and control. Developers embed applications within agents and establish interactions between distributed agents via non-intrusive message-based interfaces. This paper describes a predefined SOCIAL agent that is specialized for integrating C Language Integrated Production System (CLIPS)-based applications. The agent's high-level Application Programming Interface supports bidirectional flow of data, knowledge, and commands to other agents, enabling CLIPS applications to initiate interactions autonomously, and respond to requests and results from heterogeneous remote systems. The design and operation of CLIPS agents are illustrated with two distributed applications that integrate CLIPS-based expert systems with other intelligent systems for isolating and mapping problems in the Space Shuttle Launch Processing System at the NASA Kennedy Space Center.

  5. Model-Based Systems

    NASA Technical Reports Server (NTRS)

    Frisch, Harold P.

    2007-01-01

    Engineers, who design systems using text specification documents, focus their work upon the completed system to meet Performance, time and budget goals. Consistency and integrity is difficult to maintain within text documents for a single complex system and more difficult to maintain as several systems are combined into higher-level systems, are maintained over decades, and evolve technically and in performance through updates. This system design approach frequently results in major changes during the system integration and test phase, and in time and budget overruns. Engineers who build system specification documents within a model-based systems environment go a step further and aggregate all of the data. They interrelate all of the data to insure consistency and integrity. After the model is constructed, the various system specification documents are prepared, all from the same database. The consistency and integrity of the model is assured, therefore the consistency and integrity of the various specification documents is insured. This article attempts to define model-based systems relative to such an environment. The intent is to expose the complexity of the enabling problem by outlining what is needed, why it is needed and how needs are being addressed by international standards writing teams.

  6. The potential benefit of an advanced integrated utility system

    NASA Technical Reports Server (NTRS)

    Wolfer, B. M.

    1975-01-01

    The applicability of an advanced integrated utility system based on 1980 technology was investigated. An example of such a system, which provides electricity, heating and air conditioning, solid waste disposal, and water treatment in a single integrated plant, is illustrated for a hypothetical apartment complex. The system requires approximately 50 percent of the energy and approximately 55 percent of the water that would be required by a typical current conventional system.

  7. Principles and core functions of integrated child health information systems.

    PubMed

    Hinman, Alan R; Atkinson, Delton; Diehn, Tonya Norvell; Eichwald, John; Heberer, Jennifer; Hoyle, Therese; King, Pam; Kossack, Robert E; Williams, Donna C; Zimmerman, Amy

    2004-11-01

    Infants undergo a series of preventive and therapeutic health interventions and activities. Typically, each activity includes collection and submission of data to a dedicated information system. Subsequently, health care providers, families, and health programs must query each information system to determine the child's status in a given area. Efforts are underway to integrate information in these separate information systems. This requires specifying the core functions that integrated information systems must perform.

  8. Integration of Flex Nozzle System and Electro Hydraulic Actuators to Solid Rocket Motors

    NASA Astrophysics Data System (ADS)

    Nayani, Kishore Nath; Bajaj, Dinesh Kumar

    2017-10-01

    A rocket motor assembly comprised of solid rocket motor and flex nozzle system. Integration of flex nozzle system and hydraulic actuators to the solid rocket motors are done after transportation to the required place where integration occurred. The flex nozzle system is integrated to the rocket motor in horizontal condition and the electro hydraulic actuators are assembled to the flex nozzle systems. The electro hydraulic actuators are connected to the hydraulic power pack to operate the actuators. The nozzle-motor critical interface are insulation diametrical compression, inhibition resin-28, insulation facial compression, shaft seal `O' ring compression and face seal `O' ring compression.

  9. Risk Interfaces to Support Integrated Systems Analysis and Development

    NASA Technical Reports Server (NTRS)

    Mindock, Jennifer; Lumpkins, Sarah; Shelhamer, Mark; Anton, Wilma; Havenhill, Maria

    2016-01-01

    Objectives for systems analysis capability: Develop integrated understanding of how a complex human physiological-socio-technical mission system behaves in spaceflight. Why? Support development of integrated solutions that prevent unwanted outcomes (Implementable approaches to minimize mission resources(mass, power, crew time, etc.)); Support development of tools for autonomy (need for exploration) (Assess and maintain resilience -individuals, teams, integrated system). Output of this exercise: -Representation of interfaces based on Human System Risk Board (HSRB) Risk Summary information and simple status based on Human Research Roadmap; Consolidated HSRB information applied to support communication; Point-of-Departure for HRP Element planning; Ability to track and communicate status of collaborations. 4

  10. G189A analytical simulation of the RITE Integrated Waste Management-Water System

    NASA Technical Reports Server (NTRS)

    Coggi, J. V.; Clonts, S. E.

    1974-01-01

    This paper discusses the computer simulation of the Integrated Waste Management-Water System Using Radioisotopes for Thermal Energy (RITE) and applications of the simulation. Variations in the system temperature and flows due to particular operating conditions and variations in equipment heating loads imposed on the system were investigated with the computer program. The results were assessed from the standpoint of the computed dynamic characteristics of the system and the potential applications of the simulation to system development and vehicle integration.

  11. Integrated Computer System of Management in Logistics

    NASA Astrophysics Data System (ADS)

    Chwesiuk, Krzysztof

    2011-06-01

    This paper aims at presenting a concept of an integrated computer system of management in logistics, particularly in supply and distribution chains. Consequently, the paper includes the basic idea of the concept of computer-based management in logistics and components of the system, such as CAM and CIM systems in production processes, and management systems for storage, materials flow, and for managing transport, forwarding and logistics companies. The platform which integrates computer-aided management systems is that of electronic data interchange.

  12. Systems and methods for integrating ion mobility and ion trap mass spectrometers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ibrahim, Yehia M.; Garimella, Sandilya; Prost, Spencer A.

    Described herein are examples of systems and methods for integrating IMS and MS systems. In certain examples, systems and methods for decoding double multiplexed data are described. The systems and methods can also perform multiple refining procedures in order to minimize the demultiplexing artifacts. The systems and methods can be used, for example, for the analysis of proteomic and petroleum samples, where the integration of IMS and high mass resolution are used for accurate assignment of molecular formulae.

  13. Energy Systems Integration Newsletter | Energy Systems Integration Facility

    Science.gov Websites

    simulated sequences based on a model network. The competitive procurement process provided comparative , procurement help, design reviews, and now construction support. Miramar project support is part of integrated

  14. Renewable Electricity-to-Grid Integration | Energy Systems Integration

    Science.gov Websites

    distribution management system (ADMS) use cases at the ESIF's national, vendor-neutral ADMS test bed. Example use cases include: Integration of transmission-to-building operations for demand response

  15. Promoting research on research integrity in Canada.

    PubMed

    Master, Zubin; McDonald, Michael; Williams-Jones, Bryn

    2012-01-01

    Research on research integrity is an important element in building a strong national research integrity framework. There is a lack of empirical evidence and conceptual research on research integrity in Canada. To further strengthen and develop our system of research integrity, we believe that greater support is needed to promote research on research integrity. Research on research integrity is imperative in order to gain a richer understanding of the diversity of responsible conduct of research norms, practices, education and policies from a Canadian perspective. The knowledge gained would help in the development of an evidenced-based and responsive Canadian system of research integrity.

  16. Fuzzy adaptive integration scheme for low-cost SINS/GPS navigation system

    NASA Astrophysics Data System (ADS)

    Nourmohammadi, Hossein; Keighobadi, Jafar

    2018-01-01

    Due to weak stand-alone accuracy as well as poor run-to-run stability of micro-electro mechanical system (MEMS)-based inertial sensors, special approaches are required to integrate low-cost strap-down inertial navigation system (SINS) with global positioning system (GPS), particularly in long-term applications. This paper aims to enhance long-term performance of conventional SINS/GPS navigation systems using a fuzzy adaptive integration scheme. The main concept behind the proposed adaptive integration is the good performance of attitude-heading reference system (AHRS) in low-accelerated motions and its degradation in maneuvered or accelerated motions. Depending on vehicle maneuvers, gravity-based attitude angles can be intelligently utilized to improve orientation estimation in the SINS. Knowledge-based fuzzy inference system is developed for decision-making between the AHRS and the SINS according to vehicle maneuvering conditions. Inertial measurements are the main input data of the fuzzy system to determine the maneuvering level during the vehicle motions. Accordingly, appropriate weighting coefficients are produced to combine the SINS/GPS and the AHRS, efficiently. The assessment of the proposed integrated navigation system is conducted via real data in airborne tests.

  17. [Overall design and proof-test of an integrated environmental control and life support system (ECLSS) for demonstration and verification].

    PubMed

    Rui, Jia-bai; Zheng, Chuan-xian; Zeng, Qing-tang

    2002-12-01

    Objective. To test and demonstrate embryonic form of our future space station ECLSS, which will also form an advanced research and test ground facility. Method. The following functions of the system were tested and demonstrated: integrated solid amine CO2 collection and concentration, Sabatier CO2 reduction, urine processing thermoelectric integrated membrane evaporation, solid polymer water electrolysis O2 generation, concentrated ventilation, temperature and humidity control, the measurement and control system, and other non-regenerative techniques. All of these were demonstrated in a sealed adiabatic module, and passed the proof-tests. Result. The principal technical requirements of the system and each regenerative subsystem were met. The integration of system general and each subsystem was successful, and the partial closed loop of the system's integration has been realized basically. Conclusion. The reasonableness of the project design was verified, and the major system technical requirements were satisfied. The suitability and harmonization among system general and each subsystem were good, the system operated normally, and the parameters measured were correct.

  18. Integration of Interactive Interfaces with Intelligent Tutoring Systems: An Implementation

    DTIC Science & Technology

    1993-09-01

    Intelligent Tutoring Systems: At the crossroad of artifcial intelligence and education. Ablex Publishing Corp., Norwood, NJ. 6. Goldstein, 1. L. (1986...AD-A273 869 IImhlllII Integration of Interactive Interfaces with Intelligent Thtoring Systems: An Implementation Vijay Vasandani and T. Govindaraj...NUMBERS Integration of Interactive Interfaces with Intelligent Tutoring Systems: An Implementation C: N00014-87-K-0482 .ALITHOR(S) PE: 0602233N Vijay

  19. Flight elements: Fault detection and fault management

    NASA Technical Reports Server (NTRS)

    Lum, H.; Patterson-Hine, A.; Edge, J. T.; Lawler, D.

    1990-01-01

    Fault management for an intelligent computational system must be developed using a top down integrated engineering approach. An approach proposed includes integrating the overall environment involving sensors and their associated data; design knowledge capture; operations; fault detection, identification, and reconfiguration; testability; causal models including digraph matrix analysis; and overall performance impacts on the hardware and software architecture. Implementation of the concept to achieve a real time intelligent fault detection and management system will be accomplished via the implementation of several objectives, which are: Development of fault tolerant/FDIR requirement and specification from a systems level which will carry through from conceptual design through implementation and mission operations; Implementation of monitoring, diagnosis, and reconfiguration at all system levels providing fault isolation and system integration; Optimize system operations to manage degraded system performance through system integration; and Lower development and operations costs through the implementation of an intelligent real time fault detection and fault management system and an information management system.

  20. Development of Integrated Information System for Travel Bureau Company

    NASA Astrophysics Data System (ADS)

    Karma, I. G. M.; Susanti, J.

    2018-01-01

    Related to the effectiveness of decision-making by the management of travel bureau company, especially by managers, information serves frequent delays or incomplete. Although already computer-assisted, the existing application-based is used only handle one particular activity only, not integrated. This research is intended to produce an integrated information system that handles the overall operational activities of the company. By applying the object-oriented system development approach, the system is built with Visual Basic. Net programming language and MySQL database package. The result is a system that consists of 4 (four) separated program packages, including Reservation System, AR System, AP System and Accounting System. Based on the output, we can conclude that this system is able to produce integrated information that related to the problem of reservation, operational and financial those produce up-to-date information in order to support operational activities and decisionmaking process by related parties.

  1. Secondary School Socio-Cultural Context Influencing ICT Integration: A Case Study Approach

    ERIC Educational Resources Information Center

    Divaharan, Shanti; Ping, Lim Cher

    2010-01-01

    This paper proposes the use of activity theory and multi-level activity systems as a framework to analyse the effectiveness of ICT integration in Singapore secondary school classrooms. Three levels of activity systems are developed to study the effectiveness of ICT integration at the classroom: the classroom activity system, the department…

  2. Energy Systems Integration News | Energy Systems Integration Facility |

    Science.gov Websites

    , consider the tangible benefits it can bring to utilities and the developer community, and discuss the Energy Systems Integration Facility on July 13 and 14, 2016, to discuss current and future R&D to researching this topic from a technology, business process, and policy perspective. This workshop is an

  3. Dan Says - Continuum Magazine | NREL

    Science.gov Websites

    Dan Says Leading Energy Systems Integration A headshot of a man in a suit, smiling. Photo by Dennis U.S. dedicated to solving the complex problems associated with energy systems integration (ESI) on a national scale. Our 185,000-square-foot Energy Systems Integration Facility (ESIF) is designed to provide a

  4. 49 CFR 571.303 - Standard No. 303; Fuel system integrity of compressed natural gas vehicles.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... compressed natural gas vehicles. 571.303 Section 571.303 Transportation Other Regulations Relating to... system integrity of compressed natural gas vehicles. S1. Scope. This standard specifies requirements for the integrity of motor vehicle fuel systems using compressed natural gas (CNG), including the CNG fuel...

  5. Seeing the System: Dynamics and Complexity of Technology Integration in Secondary Schools

    ERIC Educational Resources Information Center

    Howard, Sarah K.; Thompson, Kate

    2016-01-01

    This paper introduces system dynamics modeling to understand, visualize and explore technology integration in schools, through the development of a theoretical model of technology-related change in teachers' practice. Technology integration is a dynamic social practice, within the social system of education. It is difficult, if not nearly…

  6. 28 CFR 25.5 - Validation and data integrity of records in the system.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... INFORMATION SYSTEMS The National Instant Criminal Background Check System § 25.5 Validation and data integrity... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Validation and data integrity of records... verify that the information provided to the NICS Index remains valid and correct. (b) Each data source...

  7. Integrated remote sensing and visualization (IRSV) system for transportation infrastructure operations and management, phase one, volume 4 : use of knowledge integrated visual analytics system in supporting bridge management.

    DOT National Transportation Integrated Search

    2009-12-01

    The goals of integration should be: Supporting domain oriented data analysis through the use of : knowledge augmented visual analytics system. In this project, we focus on: : Providing interactive data exploration for bridge managements. : ...

  8. UAS Integration in the NAS Project: Integrated Test and LVC Infrastructure

    NASA Technical Reports Server (NTRS)

    Murphy, Jim; Hoang, Ty

    2015-01-01

    Overview presentation of the Integrated Test and Evaluation sub-project of the Unmanned Aircraft System (UAS) in the National Airspace System (NAS). The emphasis of the presentation is the Live, Virtual, and Constructive (LVC) system (a broadly used name for classifying modeling and simulation) infrastructure and use of external assets and connection.

  9. Review of integrated digital systems: evolution and adoption

    NASA Astrophysics Data System (ADS)

    Fritz, Lawrence W.

    The factors that are influencing the evolution of photogrammetric and remote sensing technology to transition into fully integrated digital systems are reviewed. These factors include societal pressures for new, more timely digital products from the Spatial Information Sciencesand the adoption of rapid technological advancements in digital processing hardware and software. Current major developments in leading government mapping agencies of the USA, such as the Digital Production System (DPS) modernization programme at the Defense Mapping Agency, and the Automated Nautical Charting System II (ANCS-II) programme and Integrated Digital Photogrammetric Facility (IDPF) at NOAA/National Ocean Service, illustrate the significant benefits to be realized. These programmes are examples of different levels of integrated systems that have been designed to produce digital products. They provide insights to the management complexities to be considered for very large integrated digital systems. In recognition of computer industry trends, a knowledge-based architecture for managing the complexity of the very large spatial information systems of the future is proposed.

  10. Timing of Formal Phase Safety Reviews for Large-Scale Integrated Hazard Analysis

    NASA Technical Reports Server (NTRS)

    Massie, Michael J.; Morris, A. Terry

    2010-01-01

    Integrated hazard analysis (IHA) is a process used to identify and control unacceptable risk. As such, it does not occur in a vacuum. IHA approaches must be tailored to fit the system being analyzed. Physical, resource, organizational and temporal constraints on large-scale integrated systems impose additional direct or derived requirements on the IHA. The timing and interaction between engineering and safety organizations can provide either benefits or hindrances to the overall end product. The traditional approach for formal phase safety review timing and content, which generally works well for small- to moderate-scale systems, does not work well for very large-scale integrated systems. This paper proposes a modified approach to timing and content of formal phase safety reviews for IHA. Details of the tailoring process for IHA will describe how to avoid temporary disconnects in major milestone reviews and how to maintain a cohesive end-to-end integration story particularly for systems where the integrator inherently has little to no insight into lower level systems. The proposal has the advantage of allowing the hazard analysis development process to occur as technical data normally matures.

  11. Universal fuzzy integral sliding-mode controllers for stochastic nonlinear systems.

    PubMed

    Gao, Qing; Liu, Lu; Feng, Gang; Wang, Yong

    2014-12-01

    In this paper, the universal integral sliding-mode controller problem for the general stochastic nonlinear systems modeled by Itô type stochastic differential equations is investigated. One of the main contributions is that a novel dynamic integral sliding mode control (DISMC) scheme is developed for stochastic nonlinear systems based on their stochastic T-S fuzzy approximation models. The key advantage of the proposed DISMC scheme is that two very restrictive assumptions in most existing ISMC approaches to stochastic fuzzy systems have been removed. Based on the stochastic Lyapunov theory, it is shown that the closed-loop control system trajectories are kept on the integral sliding surface almost surely since the initial time, and moreover, the stochastic stability of the sliding motion can be guaranteed in terms of linear matrix inequalities. Another main contribution is that the results of universal fuzzy integral sliding-mode controllers for two classes of stochastic nonlinear systems, along with constructive procedures to obtain the universal fuzzy integral sliding-mode controllers, are provided, respectively. Simulation results from an inverted pendulum example are presented to illustrate the advantages and effectiveness of the proposed approaches.

  12. Nuclear plants gain integrated information systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Villavicencio-Ramirez, A.; Rodriquez-Alvarez, J.M.

    1994-10-01

    With the objective of simplifying the complex mesh of computing devices employed within nuclear power plants, modern technology and integration techniques are being used to form centralized (but backed up) databases and distributed processing and display networks. Benefits are immediate as a result of the integration and the use of standards. The use of a unique data acquisition and database subsystem optimizes the high costs of engineering, as this task is done only once for the life span of the system. This also contributes towards a uniform user interface and allows for graceful expansion and maintenance. This article features anmore » integrated information system, Sistema Integral de Informacion de Proceso (SIIP). The development of this system enabled the Laguna Verde Nuclear Power plant to fully use the already existing universe of signals and its related engineering during all plant conditions, namely, start up, normal operation, transient analysis, and emergency operation. Integrated systems offer many advantages over segregated systems, and this experience should benefit similar development efforts in other electric power utilities, not only for nuclear but also for other types of generating plants.« less

  13. Adaptive control system for line-commutated inverters

    NASA Technical Reports Server (NTRS)

    Dolland, C. R.; Bailey, D. A. (Inventor)

    1983-01-01

    A control system for a permanent magnet motor driven by a multiphase line commutated inverter is provided with integration for integrating the back EMF of each phase of the motor. This is used in generating system control signals for an inverter gate logic using a sync and firing angle (alpha) control generator connected to the outputs of the integrators. A precision full wave rectifier provides a speed control feedback signal to a phase delay rectifier via a gain and loop compensation circuit and to the integrators for adaptive control of the attenuation of low frequencies by the integrators as a function of motor speed. As the motor speed increases, the attenuation of low frequency components by the integrators is increased to offset the gain of the integrators to spurious low frequencies.

  14. Integrable particle systems vs solutions to the KP and 2D Toda equations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ruijsenaars, S.N.

    Starting from the relation between integrable relativistic N-particle systems with hyperbolic interactions and elementary N-soliton solutions to the KP and 2D Toda equations, we show how fusion properties of the soliton solutions are mirrored by fusion properties of the Poisson commuting particle dynamics. We also obtain previously known relations between elliptic solutions and integrable N-particle systems with elliptic interactions, without invoking finite-gap integration theory. {copyright} 1997 Academic Press, Inc.

  15. Integration Testing of Space Flight Systems

    NASA Technical Reports Server (NTRS)

    Honeycutt, Timothy; Sowards, Stephanie

    2008-01-01

    Based on the previous success' of Multi-Element Integration Testing (MEITs) for the International Space Station Program, these type of integrated tests have also been planned for the Constellation Program: MEIT (1) CEV to ISS (emulated) (2) CEV to Lunar Lander/EDS (emulated) (3) Future: Lunar Surface Systems and Mars Missions Finite Element Integration Test (FEIT) (1) CEV/CLV (2) Lunar Lander/EDS/CaL V Integrated Verification Tests (IVT) (1) Performed as a subset of the FEITs during the flight tests and then performed for every flight after Full Operational Capability (FOC) has been obtained with the flight and ground Systems.

  16. Association of Informal Clinical Integration of Physicians With Cardiac Surgery Payments.

    PubMed

    Funk, Russell J; Owen-Smith, Jason; Kaufman, Samuel A; Nallamothu, Brahmajee K; Hollingsworth, John M

    2018-05-01

    To reduce inefficiency and waste associated with care fragmentation, many current programs target greater clinical integration among physicians. However, these programs have led to only modest Medicare spending reductions. Most programs focus on formal integration, which often bears little resemblance to actual physician interaction patterns. To examine how physician interaction patterns vary between health systems and to assess whether variation in informal integration is associated with care delivery payments. National Medicare data from January 1, 2008, through December 31, 2011, identified 253 545 Medicare beneficiaries (aged ≥66 years) from 1186 health systems where Medicare beneficiaries underwent coronary artery bypass grafting (CABG) procedures. Interactions were mapped between all physicians who treated these patients-including primary care physicians and surgical and medical specialists-within a health system during their surgical episode. The level of informal integration was measured in these networks of interacting physicians. Multivariate regression models were fitted to evaluate associations between payments for each surgical episode made on a beneficiary's behalf and the level of informal integration in the health system where the patient was treated. The informal integration level of a health system. Price-standardized total surgical episode and component payments. The total 253 545 study participants included 175 520 men (69.2%; mean [SD] age, 74.51 [5.75] years) and 78 024 women (34.3%; 75.67 [5.91] years). One beneficiary of the 253 545 participants did not have sex information. The low level of informal clinical integration included 84 598 patients (33.4%; mean [SD] age, 75.00 [5.93] years); medium level, 84 442 (33.30%; 74.94 [5.87] years); and high level, 84 505 (33.34%; 74.66 [5.72] years) (P < .001). Informal integration levels varied across health systems. After adjusting for patient, health-system, and community factors, higher levels of informal integration were associated with significantly lower total episode and component payments (β coefficients for informal integration were -365.87 [95% CI, -451.08 to -280.67] for total episode payments, -182.63 [-239.80 to -125.46] for index hospitalization, -43.13 [-55.53 to -30.72] for physician services, -74.48 [-103.45 to -45.51] for hospital readmissions, and -62.04 [-88.00 to -36.07] for postacute care; P < .001 for each association). When beneficiaries were treated in health systems with higher informal integration, the greatest savings of lower estimated payments were from hospital readmissions (13.0%) and postacute care services (5.8%). Informal integration is associated with lower spending. Although most programs that seek to promote clinical integration are focused on health systems' formal structures, policy makers may also want to address informal integration.

  17. Integrated track stability assessment and monitoring system (ITSAMS).

    DOT National Transportation Integrated Search

    2006-10-01

    The overall objective of project is to continue the development of remote sensing : technologies that can be integrated and deployed in a mobile inspection vehicle i.e. Integrated : Track Stability Assessment and Monitoring System (ITSAMS).

  18. Ares I Integrated Vehicle System Safety Team

    NASA Technical Reports Server (NTRS)

    Wetherholt, Jon; McNairy, Lisa; Shackelford, Carla

    2009-01-01

    Complex systems require integrated analysis teams which sometimes are divided into subsystem teams. Proper division of the analysis in to subsystem teams is important. Safety analysis is one of the most difficult aspects of integration.

  19. Formal Integrals and Noether Operators of Nonlinear Hyperbolic Partial Differential Systems Admitting a Rich Set of Symmetries

    NASA Astrophysics Data System (ADS)

    Startsev, Sergey Ya.

    2017-05-01

    The paper is devoted to hyperbolic (generally speaking, non-Lagrangian and nonlinear) partial differential systems possessing a full set of differential operators that map any function of one independent variable into a symmetry of the corresponding system. We demonstrate that a system has the above property if and only if this system admits a full set of formal integrals (i.e., differential operators which map symmetries into integrals of the system). As a consequence, such systems possess both direct and inverse Noether operators (in the terminology of a work by B. Fuchssteiner and A.S. Fokas who have used these terms for operators that map cosymmetries into symmetries and perform transformations in the opposite direction). Systems admitting Noether operators are not exhausted by Euler-Lagrange systems and the systems with formal integrals. In particular, a hyperbolic system admits an inverse Noether operator if a differential substitution maps this system into a system possessing an inverse Noether operator.

  20. High-Precision Image Aided Inertial Navigation with Known Features: Observability Analysis and Performance Evaluation

    PubMed Central

    Jiang, Weiping; Wang, Li; Niu, Xiaoji; Zhang, Quan; Zhang, Hui; Tang, Min; Hu, Xiangyun

    2014-01-01

    A high-precision image-aided inertial navigation system (INS) is proposed as an alternative to the carrier-phase-based differential Global Navigation Satellite Systems (CDGNSSs) when satellite-based navigation systems are unavailable. In this paper, the image/INS integrated algorithm is modeled by a tightly-coupled iterative extended Kalman filter (IEKF). Tightly-coupled integration ensures that the integrated system is reliable, even if few known feature points (i.e., less than three) are observed in the images. A new global observability analysis of this tightly-coupled integration is presented to guarantee that the system is observable under the necessary conditions. The analysis conclusions were verified by simulations and field tests. The field tests also indicate that high-precision position (centimeter-level) and attitude (half-degree-level)-integrated solutions can be achieved in a global reference. PMID:25330046

  1. ProcessGene-Connect: SOA Integration between Business Process Models and Enactment Transactions of Enterprise Software Systems

    NASA Astrophysics Data System (ADS)

    Wasser, Avi; Lincoln, Maya

    In recent years, both practitioners and applied researchers have become increasingly interested in methods for integrating business process models and enterprise software systems through the deployment of enabling middleware. Integrative BPM research has been mainly focusing on the conversion of workflow notations into enacted application procedures, and less effort has been invested in enhancing the connectivity between design level, non-workflow business process models and related enactment systems such as: ERP, SCM and CRM. This type of integration is useful at several stages of an IT system lifecycle, from design and implementation through change management, upgrades and rollout. The paper presents an integration method that utilizes SOA for connecting business process models with corresponding enterprise software systems. The method is then demonstrated through an Oracle E-Business Suite procurement process and its ERP transactions.

  2. Integrated restructurable flight control system demonstration results

    NASA Technical Reports Server (NTRS)

    Weiss, Jerold L.; Hsu, John Y.

    1987-01-01

    The purpose of this study was to examine the complementary capabilities of several restructurable flight control system (RFCS) concepts through the integration of these technologies into a complete system. Performance issues were addressed through a re-examination of RFCS functional requirements, and through a qualitative analysis of the design issues that, if properly addressed during integration, will lead to the highest possible degree of fault-tolerant performance. Software developed under previous phases of this contract and under NAS1-18004 was modified and integrated into a complete RFCS subroutine for NASA's B-737 simulation. The integration of these modules involved the development of methods for dealing with the mismatch between the outputs of the failure detection module and the input requirements of the automatic control system redesign module. The performance of this demonstration system was examined through extensive simulation trials.

  3. Human Systems Integration in the Federal Government

    NASA Technical Reports Server (NTRS)

    Jones, Patricia M.; Graves, Gaye L.; Allard, Terry; Blackhurst, Jack; Fitts, David J.; Peters, Sean; Piccione, Dino; Shattuck, Lawrence G.

    2010-01-01

    Human Systems Integration principles and methods can be used to help integrate people, technology, and organizations in an effective and efficient manner. Over the past decade, a wide range of tools, techniques, and technologies have been developed by federal agencies to achieve significant cost and performance benefits. In this discussion, we will explore trends in military human systems integration and learn about the critical role being played by human performance and effectiveness research. We will also examine case studies on the planning and design of future human space flight vehicles, the national air space system and the first nuclear reactors to be built in the United States in over 30 years. And with an eye toward sustaining the discipline s principles and methods, we ll take a look at educating and training the next generation of human systems integration practitioners.

  4. 75 FR 1617 - Draft Toxicological Review of Methanol: In Support of the Summary Information in the Integrated...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-12

    ... on the Integrated Risk Information System (IRIS)'' (EPA/635/R-09/013). The draft document was... ``Toxicological Review of Methanol: In Support of Summary Information on the Integrated Risk Information System... Toxicological Review of Methanol: In Support of the Summary Information in the Integrated Risk Information...

  5. 75 FR 69065 - Draft Toxicological Review of Urea: In Support of Summary Information on the Integrated Risk...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-10

    ... Summary Information on the Integrated Risk Information System (IRIS) AGENCY: Environmental Protection..., ``Toxicological Review of Urea: In Support of Summary Information on the Integrated Risk Information System (IRIS...: The draft ``Toxicological Review of Urea: In Support of Summary Information on the Integrated Risk...

  6. 76 FR 54228 - Draft Toxicological Review of Acrylonitrile: In Support of Summary Information on the Integrated...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-31

    ... Toxicological Review of Acrylonitrile: In Support of Summary Information on the Integrated Risk Information... Acrylonitrile: In Support of Summary Information on the Integrated Risk Information System (IRIS)'' (EPA/635/R... Acrylonitrile: In Support of Summary Information on the Integrated Risk Information System (IRIS)'' is available...

  7. Integration of Gross Anatomy in an Organ System-Based Medical Curriculum: Strategies and Challenges

    ERIC Educational Resources Information Center

    Brooks, William S.; Woodley, Kristina T. C. Panizzi; Jackson, James R.; Hoesley, Craig J.

    2015-01-01

    The University of Alabama School of Medicine (UASOM) instituted a fully integrated, organ system-based preclinical curriculum in 2007. Gross anatomy and embryology were integrated with other basic science disciplines throughout the first two years of undergraduate medical education. Here we describe the methods of instruction and integration of…

  8. Dealing with Sensory Integrative Dysfunction in the Classroom: A Guide for Early Elementary Teachers.

    ERIC Educational Resources Information Center

    Chan, Christina

    This paper offers teachers basic information about sensory integration and suggests strategies for managing classrooms which include children with sensory integrative dysfunction. The first section looks at what sensory integration is, noting especially the roles of the three "near senses": the vestibular system, the proprioceptive system, and the…

  9. Problems related to the integration of fault tolerant aircraft electronic systems

    NASA Technical Reports Server (NTRS)

    Bannister, J. A.; Adlakha, V.; Triyedi, K.; Alspaugh, T. A., Jr.

    1982-01-01

    Problems related to the design of the hardware for an integrated aircraft electronic system are considered. Taxonomies of concurrent systems are reviewed and a new taxonomy is proposed. An informal methodology intended to identify feasible regions of the taxonomic design space is described. Specific tools are recommended for use in the methodology. Based on the methodology, a preliminary strawman integrated fault tolerant aircraft electronic system is proposed. Next, problems related to the programming and control of inegrated aircraft electronic systems are discussed. Issues of system resource management, including the scheduling and allocation of real time periodic tasks in a multiprocessor environment, are treated in detail. The role of software design in integrated fault tolerant aircraft electronic systems is discussed. Conclusions and recommendations for further work are included.

  10. ECLSS and Thermal Systems Integration Challenges Across the Constellation Architecture

    NASA Technical Reports Server (NTRS)

    Carrasquillo, Robyn

    2010-01-01

    As the Constellation Program completes its initial capability Preliminary Design Review milestone for the Initial Capability phase, systems engineering of the Environmental Control and Life Support (ECLS) and Thermal Systems for the various architecture elements has progressed from the requirements to design phase. As designs have matured for the Ares, Orion, Ground Systems, and Extravehicular (EVA) System, a number of integration challenges have arisen requiring analyses and trades, resulting in changes to the design and/or requirements. This paper will address some of the key integration issues and results, including the Orion-to-Ares shared compartment venting and purging, Orion-to-EVA suit loop integration issues with the suit system, Orion-to-ISS and Orion-to-Altair intermodule ventilation, and Orion and Ground Systems impacts from post-landing environments.

  11. Addressing System Reconfiguration and Incremental Integration within IMA Systems

    NASA Astrophysics Data System (ADS)

    Ferrero, F.; Rodríques, A. I.

    2009-05-01

    Recently space industry is paying special attention to Integrated Modular Avionics (IMA) systems due to the benefits that modular concepts could bring to the development of space applications, especially in terms of interoperability, flexibility and software reuse. Two important IMA goals to be highlighted are system reconfiguration, and incremental integration of new functionalities into a pre-existing system. The purpose of this paper is to show how system reconfiguration is conducted based on Allied Standard Avionics Architecture Council (ASAAC) concepts for IMA Systems. Besides, it aims to provide a proposal for addressing the incremental integration concept supported by our experience gained during European Technology Acquisition Program (ETAP) TDP1.7 programme. All these topics will be discussed taking into account safety issues and showing the blueprint as an appropriate technique to support these concepts.

  12. Geometric integrator for simulations in the canonical ensemble

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tapias, Diego, E-mail: diego.tapias@nucleares.unam.mx; Sanders, David P., E-mail: dpsanders@ciencias.unam.mx; Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139

    2016-08-28

    We introduce a geometric integrator for molecular dynamics simulations of physical systems in the canonical ensemble that preserves the invariant distribution in equations arising from the density dynamics algorithm, with any possible type of thermostat. Our integrator thus constitutes a unified framework that allows the study and comparison of different thermostats and of their influence on the equilibrium and non-equilibrium (thermo-)dynamic properties of a system. To show the validity and the generality of the integrator, we implement it with a second-order, time-reversible method and apply it to the simulation of a Lennard-Jones system with three different thermostats, obtaining good conservationmore » of the geometrical properties and recovering the expected thermodynamic results. Moreover, to show the advantage of our geometric integrator over a non-geometric one, we compare the results with those obtained by using the non-geometric Gear integrator, which is frequently used to perform simulations in the canonical ensemble. The non-geometric integrator induces a drift in the invariant quantity, while our integrator has no such drift, thus ensuring that the system is effectively sampling the correct ensemble.« less

  13. Integrated Avionics System (IAS), Integrating 3-D Technology On A Spacecraft Panel

    NASA Technical Reports Server (NTRS)

    Hunter, Don J.; Halpert, Gerald

    1999-01-01

    As spacecraft designs converge toward miniaturization, and with the volumetric and mass challenges placed on avionics, programs will continue to advance the "state of the art" in spacecraft system development with new challenges to reduce power, mass and volume. Traditionally, the trend is to focus on high-density 3-D packaging technologies. Industry has made significant progress in 3-D technologies, and other related internal and external interconnection schemes. Although new technologies have improved packaging densities, a system packaging architecture is required that not only reduces spacecraft volume and mass budgets, but increase integration efficiencies, provide modularity and flexibility to accommodate multiple missions while maintaining a low recurring cost. With these challenges in mind, a novel system packaging approach incorporates solutions that provide broader environmental applications, more flexible system interconnectivity, scalability, and simplified assembly test and integration schemes. The Integrated Avionics System (IAS) provides for a low-mass, modular distributed or centralized packaging architecture which combines ridged-flex technologies, high-density COTS hardware and a new 3-D mechanical packaging approach, Horizontal Mounted Cube (HMC). This paper will describe the fundamental elements of the IAS, HMC hardware design, system integration and environmental test results.

  14. Intelligent Integrated System Health Management

    NASA Technical Reports Server (NTRS)

    Figueroa, Fernando

    2012-01-01

    Intelligent Integrated System Health Management (ISHM) is the management of data, information, and knowledge (DIaK) with the purposeful objective of determining the health of a system (Management: storage, distribution, sharing, maintenance, processing, reasoning, and presentation). Presentation discusses: (1) ISHM Capability Development. (1a) ISHM Knowledge Model. (1b) Standards for ISHM Implementation. (1c) ISHM Domain Models (ISHM-DM's). (1d) Intelligent Sensors and Components. (2) ISHM in Systems Design, Engineering, and Integration. (3) Intelligent Control for ISHM-Enabled Systems

  15. Fundamentals of fuel cell system integration

    NASA Astrophysics Data System (ADS)

    Krumpelt, Michael; Kumar, Romesh; Myles, Kevin M.

    1994-04-01

    Fuel cells are theoretically very efficient energy conversion devices that have the potential of becoming a commercial product for numerous uses in the civilian economy. We have analyzed several fuel cell system designs with regard to thermal and chemical integration of the fuel cell stack into the rest of the system. Thermal integration permits the use of the stack waste heat for the endothermic steps of fuel reforming. Chemical integration provides the steam needed for fuel reforming from the water produced by the electrochemical cell reaction. High-temperature fuel cells, such as the molten carbonate and the solid oxide fuel cells, permit this system integration in a relatively simple manner. Lower temperature fuel cells, such as the polymer electrolyte and phosphoric acid systems, require added system complexity to achieve such integration. The system economics are affected by capital and fuel costs and technical parameters, such as electrochemical fuel utilization, current density, and system complexity. At today's low fuel prices and the high fuel cell costs (in part, because of the low rates of production of the early prototypes), fuel cell systems are not cost competitive with conventional power generation. With the manufacture and sale of larger numbers of fuel cell systems, the total costs will decrease from the current several thousand dollars per kW, to perhaps less than $100 per kW as production volumes approa ch a million units per year.

  16. System interface for an integrated intelligent safety system (ISS) for vehicle applications.

    PubMed

    Hannan, Mahammad A; Hussain, Aini; Samad, Salina A

    2010-01-01

    This paper deals with the interface-relevant activity of a vehicle integrated intelligent safety system (ISS) that includes an airbag deployment decision system (ADDS) and a tire pressure monitoring system (TPMS). A program is developed in LabWindows/CVI, using C for prototype implementation. The prototype is primarily concerned with the interconnection between hardware objects such as a load cell, web camera, accelerometer, TPM tire module and receiver module, DAQ card, CPU card and a touch screen. Several safety subsystems, including image processing, weight sensing and crash detection systems, are integrated, and their outputs are combined to yield intelligent decisions regarding airbag deployment. The integrated safety system also monitors tire pressure and temperature. Testing and experimentation with this ISS suggests that the system is unique, robust, intelligent, and appropriate for in-vehicle applications.

  17. Integrating the human element into the systems engineering process and MBSE methodology

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tadros, Michael Samir

    In response to the challenges related to the increasing size and complexity of systems, organizations have recognized the need to integrate human considerations in the beginning stages of systems development. Human Systems Integration (HSI) seeks to accomplish this objective by incorporating human factors within systems engineering (SE) processes and methodologies, which is the focus of this paper. A representative set of HSI methods from multiple sources are organized, analyzed, and mapped to the systems engineering Vee-model. These methods are then consolidated and evaluated against the SE process and Models-Based Systems Engineering (MBSE) methodology to determine where and how they couldmore » integrate within systems development activities in the form of specific enhancements. Overall conclusions based on these evaluations are presented and future research areas are proposed.« less

  18. System Interface for an Integrated Intelligent Safety System (ISS) for Vehicle Applications

    PubMed Central

    Hannan, Mahammad A.; Hussain, Aini; Samad, Salina A.

    2010-01-01

    This paper deals with the interface-relevant activity of a vehicle integrated intelligent safety system (ISS) that includes an airbag deployment decision system (ADDS) and a tire pressure monitoring system (TPMS). A program is developed in LabWindows/CVI, using C for prototype implementation. The prototype is primarily concerned with the interconnection between hardware objects such as a load cell, web camera, accelerometer, TPM tire module and receiver module, DAQ card, CPU card and a touch screen. Several safety subsystems, including image processing, weight sensing and crash detection systems, are integrated, and their outputs are combined to yield intelligent decisions regarding airbag deployment. The integrated safety system also monitors tire pressure and temperature. Testing and experimentation with this ISS suggests that the system is unique, robust, intelligent, and appropriate for in-vehicle applications. PMID:22205861

  19. Integration Process for the Habitat Demonstration Unit

    NASA Technical Reports Server (NTRS)

    Gill, Tracy; Merbitz, Jerad; Kennedy, Kriss; Tri, Terry; Howe, A. Scott

    2010-01-01

    The Habitat Demonstration Unit (HDU) is an experimental exploration habitat technology and architecture test platform designed for analog demonstration activities The HDU project has required a team to integrate a variety of contributions from NASA centers and outside collaborators and poses a challenge in integrating these disparate efforts into a cohesive architecture To complete the development of the HDU from conception in June 2009 to rollout for operations in July 2010, a cohesive integration strategy has been developed to integrate the various systems of HDU and the payloads, such as the Geology Lab, that those systems will support The utilization of interface design standards and uniquely tailored reviews have allowed for an accelerated design process Scheduled activities include early fit-checks and the utilization of a Habitat avionics test bed prior to equipment installation into HDU A coordinated effort to utilize modeling and simulation systems has aided in design and integration concept development Modeling tools have been effective in hardware systems layout, cable routing and length estimation, and human factors analysis Decision processes on the shell development including the assembly sequence and the transportation have been fleshed out early on HDU to maximize the efficiency of both integration and field operations Incremental test operations leading up to an integrated systems test allows for an orderly systems test program The HDU will begin its journey as an emulation of a Pressurized Excursion Module (PEM) for 2010 field testing and then may evolve to a Pressurized Core Module (PCM) for 2011 and later field tests, depending on agency architecture decisions The HDU deployment will vary slightly from current lunar architecture plans to include developmental hardware and software items and additional systems called opportunities for technology demonstration One of the HDU challenges has been designing to be prepared for the integration of presently unanticipated systems Results of the HDU field tests will influence future designs of habitat systems.

  20. A Physician's Perspective On Vertical Integration.

    PubMed

    Berenson, Robert A

    2017-09-01

    Vertical integration has been a central feature of health care delivery system change for more than two decades. Recent studies have demonstrated that vertically integrated health care systems raise prices and costs without observable improvements in quality, despite many theoretical reasons why cost control and improved quality might occur. Less well studied is how physicians view their newfound partnerships with hospitals. In this article I review literature findings and other observations on five aspects of vertical integration that affect physicians in their professional and personal lives: patients' access to physicians, physician compensation, autonomy versus system support, medical professionalism and culture, and lifestyle. I conclude that the movement toward physicians' alignment with and employment in vertically integrated systems seems inexorable but that policy should not promote such integration either intentionally or inadvertently. Instead, policy should address the flaws in current payment approaches that reward high prices and excessive service use-outcomes that vertical integration currently produces. Project HOPE—The People-to-People Health Foundation, Inc.

  1. Design of the Hospital Integrated Information Management System Based on Cloud Platform

    PubMed Central

    Aijing, L; Jin, Y

    2015-01-01

    ABSTRACT At present, the outdated information management style cannot meet the needs of hospital management, and has become the bottleneck of hospital's management and development. In order to improve the integrated management of information, hospitals have increased their investment in integrated information management systems. On account of the lack of reasonable and scientific design, some hospital integrated information management systems have common problems, such as unfriendly interface, poor portability and maintainability, low security and efficiency, lack of interactivity and information sharing. To solve the problem, this paper carries out the research and design of a hospital information management system based on cloud platform, which can realize the optimized integration of hospital information resources and save money. PMID:27399033

  2. Predicted performance benefits of an adaptive digital engine control system of an F-15 airplane

    NASA Technical Reports Server (NTRS)

    Burcham, F. W., Jr.; Myers, L. P.; Ray, R. J.

    1985-01-01

    The highly integrated digital electronic control (HIDEC) program will demonstrate and evaluate the improvements in performance and mission effectiveness that result from integrating engine-airframe control systems. Currently this is accomplished on the NASA Ames Research Center's F-15 airplane. The two control modes used to implement the systems are an integrated flightpath management mode and in integrated adaptive engine control system (ADECS) mode. The ADECS mode is a highly integrated mode in which the airplane flight conditions, the resulting inlet distortion, and the available engine stall margin are continually computed. The excess stall margin is traded for thrust. The predicted increase in engine performance due to the ADECS mode is presented in this report.

  3. Integrated Collision Avoidance System for Air Vehicle

    NASA Technical Reports Server (NTRS)

    Lin, Ching-Fang (Inventor)

    2013-01-01

    Collision with ground/water/terrain and midair obstacles is one of the common causes of severe aircraft accidents. The various data from the coremicro AHRS/INS/GPS Integration Unit, terrain data base, and object detection sensors are processed to produce collision warning audio/visual messages and collision detection and avoidance of terrain and obstacles through generation of guidance commands in a closed-loop system. The vision sensors provide more information for the Integrated System, such as, terrain recognition and ranging of terrain and obstacles, which plays an important role to the improvement of the Integrated Collision Avoidance System.

  4. 2. View, structures in Systems Integration Laboratory complex, looking north. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. View, structures in Systems Integration Laboratory complex, looking north. The Components Test Laboratory (T-27) is located in the immediate foreground. Immediately uphill to the left of T-27 is the Boiler Chiller Plant (T-28H). To the left of T-28H is the Oxidizer Conditioning Structure (T-28D). Behind the T-28D is the Long-Term Oxidizer Silo (T-28B). The twin gantry structure at the left is the Systems Integration Laboratory (T-28). - Air Force Plant PJKS, Systems Integration Laboratory, Waterton Canyon Road & Colorado Highway 121, Lakewood, Jefferson County, CO

  5. Space Station Freedom Environmental Control and Life Support System (ECLSS) phase 3 simplified integrated test trace contaminant control subsystem performance

    NASA Technical Reports Server (NTRS)

    Perry, J. L.

    1990-01-01

    Space Station Freedom environmental control and life support system testing has been conducted at Marshall Space Flight Center since 1986. The phase 3 simplified integrated test (SIT) conducted from July 30, 1989, through August 11, 1989, tested an integrated air revitalization system. During this test, the trace contaminant control subsystem (TCCS) was directly integrated with the bleed stream from the carbon dioxide reduction subsystem. The TCCS performed as expected with minor anomalies. The test set the basis for further characterizing the TCCS performance as part of advance air revitalization system configurations.

  6. Special Medicare reimbursement and fraud and abuse considerations for management services organizations, medical foundations, and integrated delivery systems.

    PubMed

    DeMuro, P R; Owens, J F

    1994-01-01

    This chapter discusses certain Medicare reimbursement and fraud and abuse considerations for management services organizations (MSOs), medical foundations, and integrated delivery systems. It stresses the necessity of a business plan, the sources of capitalization that might be used in creating an integrated delivery system, and their effect on Medicare reimbursement. It also discusses related party principles and considerations and the Medicare "incident to" regulations. Furthermore, it discusses the application of certain Medicare safe harbor regulations on MSOs' structures and services, and those of medical foundations and integrated delivery systems.

  7. 1. View, structures in Systems Integration Laboratory complex, looking northwest. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. View, structures in Systems Integration Laboratory complex, looking northwest. The twin gantry structure in the center is the Systems Integration Laboratory (T-28). To its immediate left in the foreground is a truck well, concrete retaining wall, piping, and stack associated with the oxidizer vault storage area. To the immediate right of T-28 is the concrete Signal Transfer Building (T-28A). At the extreme right is the Long-Term Hydrazine Silo (T-28E). - Air Force Plant PJKS, Systems Integration Laboratory, Waterton Canyon Road & Colorado Highway 121, Lakewood, Jefferson County, CO

  8. Flight Test Evaluation of Situation Awareness Benefits of Integrated Synthetic Vision System Technology f or Commercial Aircraft

    NASA Technical Reports Server (NTRS)

    Prinzel, Lawrence J., III; Kramer, Lynda J.; Arthur, Jarvis J., III

    2005-01-01

    Research was conducted onboard a Gulfstream G-V aircraft to evaluate integrated Synthetic Vision System concepts during flight tests over a 6-week period at the Wallops Flight Facility and Reno/Tahoe International Airport. The NASA Synthetic Vision System incorporates database integrity monitoring, runway incursion prevention alerting, surface maps, enhanced vision sensors, and advanced pathway guidance and synthetic terrain presentation. The paper details the goals and objectives of the flight test with a focus on the situation awareness benefits of integrating synthetic vision system enabling technologies for commercial aircraft.

  9. A method for exponential propagation of large systems of stiff nonlinear differential equations

    NASA Technical Reports Server (NTRS)

    Friesner, Richard A.; Tuckerman, Laurette S.; Dornblaser, Bright C.; Russo, Thomas V.

    1989-01-01

    A new time integrator for large, stiff systems of linear and nonlinear coupled differential equations is described. For linear systems, the method consists of forming a small (5-15-term) Krylov space using the Jacobian of the system and carrying out exact exponential propagation within this space. Nonlinear corrections are incorporated via a convolution integral formalism; the integral is evaluated via approximate Krylov methods as well. Gains in efficiency ranging from factors of 2 to 30 are demonstrated for several test problems as compared to a forward Euler scheme and to the integration package LSODE.

  10. How to assess and prepare health systems in low- and middle-income countries for integration of services—a systematic review

    PubMed Central

    Joshi, Rohina; Negin, Joel

    2018-01-01

    Abstract Despite growing support for integration of frontline services, a lack of information about the pre-conditions necessary to integrate such services hampers the ability of policy makers and implementers to assess how feasible or worthwhile integration may be, especially in low- and middle-income countries (LMICs). We adopted a modified systematic review with aspects of realist review, including quantitative and qualitative studies that incorporated assessment of health system preparedness for and capacity to implement integrated services. We searched Medline via Ovid, Web of Science and the Cochrane library using terms adapted from Dudley and Garner’s systematic review on integration in LMICs. From an initial list of 10 550 articles, 206 were selected for full-text review by two reviewers who independently reviewed articles and inductively extracted and synthesized themes related to health system preparedness. We identified five ‘context’ related categories and four health system ‘capability’ themes. The contextual enabling and constraining factors for frontline service integration were: (1) the organizational framework of frontline services, (2) health care worker preparedness, (3) community and client preparedness, (4) upstream logistics and (5) policy and governance issues. The intersecting health system capabilities identified were the need for: (1) sufficiently functional frontline health services, (2) sufficiently trained and motivated health care workers, (3) availability of technical tools and equipment suitable to facilitate integrated frontline services and (4) appropriately devolved authority and decision-making processes to enable frontline managers and staff to adapt integration to local circumstances. Moving beyond claims that integration is defined differently by different programs and thus unsuitable for comparison, this review demonstrates that synthesis is possible. It presents a common set of contextual factors and health system capabilities necessary for successful service integration which may be considered indicators of preparedness and could form the basis for an ‘integration preparedness tool’. PMID:29272396

  11. How to assess and prepare health systems in low- and middle-income countries for integration of services-a systematic review.

    PubMed

    Topp, Stephanie M; Abimbola, Seye; Joshi, Rohina; Negin, Joel

    2018-03-01

    Despite growing support for integration of frontline services, a lack of information about the pre-conditions necessary to integrate such services hampers the ability of policy makers and implementers to assess how feasible or worthwhile integration may be, especially in low- and middle-income countries (LMICs). We adopted a modified systematic review with aspects of realist review, including quantitative and qualitative studies that incorporated assessment of health system preparedness for and capacity to implement integrated services. We searched Medline via Ovid, Web of Science and the Cochrane library using terms adapted from Dudley and Garner's systematic review on integration in LMICs. From an initial list of 10 550 articles, 206 were selected for full-text review by two reviewers who independently reviewed articles and inductively extracted and synthesized themes related to health system preparedness. We identified five 'context' related categories and four health system 'capability' themes. The contextual enabling and constraining factors for frontline service integration were: (1) the organizational framework of frontline services, (2) health care worker preparedness, (3) community and client preparedness, (4) upstream logistics and (5) policy and governance issues. The intersecting health system capabilities identified were the need for: (1) sufficiently functional frontline health services, (2) sufficiently trained and motivated health care workers, (3) availability of technical tools and equipment suitable to facilitate integrated frontline services and (4) appropriately devolved authority and decision-making processes to enable frontline managers and staff to adapt integration to local circumstances. Moving beyond claims that integration is defined differently by different programs and thus unsuitable for comparison, this review demonstrates that synthesis is possible. It presents a common set of contextual factors and health system capabilities necessary for successful service integration which may be considered indicators of preparedness and could form the basis for an 'integration preparedness tool'. © The Author 2017. Published by Oxford University Press in association with The London School of Hygiene and Tropical Medicine.

  12. BIO-Plex Information System Concept

    NASA Technical Reports Server (NTRS)

    Jones, Harry; Boulanger, Richard; Arnold, James O. (Technical Monitor)

    1999-01-01

    This paper describes a suggested design for an integrated information system for the proposed BIO-Plex (Bioregenerative Planetary Life Support Systems Test Complex) at Johnson Space Center (JSC), including distributed control systems, central control, networks, database servers, personal computers and workstations, applications software, and external communications. The system will have an open commercial computing and networking, architecture. The network will provide automatic real-time transfer of information to database server computers which perform data collection and validation. This information system will support integrated, data sharing applications for everything, from system alarms to management summaries. Most existing complex process control systems have information gaps between the different real time subsystems, between these subsystems and central controller, between the central controller and system level planning and analysis application software, and between the system level applications and management overview reporting. An integrated information system is vitally necessary as the basis for the integration of planning, scheduling, modeling, monitoring, and control, which will allow improved monitoring and control based on timely, accurate and complete data. Data describing the system configuration and the real time processes can be collected, checked and reconciled, analyzed and stored in database servers that can be accessed by all applications. The required technology is available. The only opportunity to design a distributed, nonredundant, integrated system is before it is built. Retrofit is extremely difficult and costly.

  13. The SIMPSONS project: An integrated Mars transportation system

    NASA Astrophysics Data System (ADS)

    Kaplan, Matthew; Carlson, Eric; Bradfute, Sherie; Allen, Kent; Duvergne, Francois; Hernandez, Bert; Le, David; Nguyen, Quan; Thornhill, Brett

    In response to the Request for Proposal (RFP) for an integrated transportation system network for an advanced Martian base, Frontier Transportation Systems (FTS) presents the results of the SIMPSONS project (Systems Integration for Mars Planetary Surface Operations Networks). The following topics are included: the project background, vehicle design, future work, conclusions, management status, and cost breakdown. The project focuses solely on the surface-to-surface transportation at an advanced Martian base.

  14. Propulsion System and Orbit Maneuver Integration in CubeSats: Trajectory Control Strategies Using Micro Ion Propulsion

    NASA Technical Reports Server (NTRS)

    Hudson, Jennifer; Martinez, Andres; Petro, Andrew

    2015-01-01

    The Propulsion System and Orbit Maneuver Integration in CubeSats project aims to solve the challenges of integrating a micro electric propulsion system on a CubeSat in order to perform orbital maneuvers and control attitude. This represents a fundamentally new capability for CubeSats, which typically do not contain propulsion systems and cannot maneuver far beyond their initial orbits.

  15. The SIMPSONS project: An integrated Mars transportation system

    NASA Technical Reports Server (NTRS)

    Kaplan, Matthew; Carlson, Eric; Bradfute, Sherie; Allen, Kent; Duvergne, Francois; Hernandez, Bert; Le, David; Nguyen, Quan; Thornhill, Brett

    1992-01-01

    In response to the Request for Proposal (RFP) for an integrated transportation system network for an advanced Martian base, Frontier Transportation Systems (FTS) presents the results of the SIMPSONS project (Systems Integration for Mars Planetary Surface Operations Networks). The following topics are included: the project background, vehicle design, future work, conclusions, management status, and cost breakdown. The project focuses solely on the surface-to-surface transportation at an advanced Martian base.

  16. Systems Engineering Processes Applied to Ground Vehicle Integration at US Army Tank Automotive Research, Development, and Engineering Center (TARDEC)

    DTIC Science & Technology

    2010-08-19

    UNCLASSIFIED Systems Engineering Processes Applied To Ground Vehicle Integration at US Army Tank Automotive Research, Development, and Engineering...DATES COVERED - 4. TITLE AND SUBTITLE Systems Engineering Processes Applied To Ground Vehicle Integration at US Army Tank Automotive Research...release, distribution unlimited 13. SUPPLEMENTARY NOTES Presented at NDIAs Ground Vehicle Systems Engineering and Technology Symposium (GVSETS), 17 22

  17. Integrating Character Education Model With Spiral System In Chemistry Subject

    NASA Astrophysics Data System (ADS)

    Hartutik; Rusdarti; Sumaryanto; Supartono

    2017-04-01

    Integrating character education is the responsibility of all subject teachers including chemistry teacher. The integration of character education is just administrative requirements so that the character changes are not measurable. The research objective 1) describing the actual conditions giving character education, 2) mapping the character integration of chemistry syllabus with a spiral system, and 3) producing syllabus and guide system integrating character education in chemistry lessons. Of the eighteen value character, each character is mapped to the material chemistry value concepts of class X and repeated the system in class XI and class XII. Spiral system integration means integrating the character values of chemistry subjects in steps from class X to XII repeatedly at different depth levels. Besides developing the syllabus, also made the integration of characters in a learning guide. This research was designed with research and development [3] with the scope of 20 chemistry teachers in Semarang. The focus of the activities is the existence of the current character study, mapping the character values in the syllabus, and assessment of the integration guides of character education. The validity test of Syllabus and Lesson Plans by experts in FGD. The data were taken with questionnaire and interviews, then processed by descriptive analysis. The result shows 1) The factual condition, in general, the teachers designed learning one-time face-to-face with the integration of more than four characters so that behaviour changes and depth of character is poorly controlled, 2) Mapping each character values focused in the syllabus. Meaning, on one or two basic competence in four or five times, face to face, enough integrated with the value of one character. In this way, there are more noticeable changes in students behaviour. Guidance is needed to facilitate the integration of character education for teachers integrating systems. Product syllabus and guidelines validated by experts and the syllabus results averaging 4.37; guidebooks integrating character education in chemistry learning 4.36 with a maximum score of 5. Thus the device is declared valid. Through focus group discussions, each expert gave input for the improvement of learning modules of character education.

  18. Integration Process for the Habitat Demonstration Unit

    NASA Technical Reports Server (NTRS)

    Gill, Tracy; Merbitz, Jerad; Kennedy, Kriss; Tn, Terry; Toups, Larry; Howe, A. Scott; Smitherman, David

    2011-01-01

    The Habitat Demonstration Unit (HDU) is an experimental exploration habitat technology and architecture test platform designed for analog demonstration activities. The HDU previously served as a test bed for testing technologies and sub-systems in a terrestrial surface environment. in 2010 in the Pressurized Excursion Module (PEM) configuration. Due to the amount of work involved to make the HDU project successful, the HDU project has required a team to integrate a variety of contributions from NASA centers and outside collaborators The size of the team and number of systems involved With the HDU makes Integration a complicated process. However, because the HDU shell manufacturing is complete, the team has a head start on FY--11 integration activities and can focus on integrating upgrades to existing systems as well as integrating new additions. To complete the development of the FY-11 HDU from conception to rollout for operations in July 2011, a cohesive integration strategy has been developed to integrate the various systems of HDU and the payloads. The highlighted HDU work for FY-11 will focus on performing upgrades to the PEM configuration, adding the X-Hab as a second level, adding a new porch providing the astronauts a larger work area outside the HDU for EVA preparations, and adding a Hygiene module. Together these upgrades result in a prototype configuration of the Deep Space Habitat (DSH), an element under evaluation by NASA's Human Exploration Framework Team (HEFT) Scheduled activates include early fit-checks and the utilization of a Habitat avionics test bed prior to installation into HDU. A coordinated effort to utilize modeling and simulation systems has aided in design and integration concept development. Modeling tools have been effective in hardware systems layout, cable routing, sub-system interface length estimation and human factors analysis. Decision processes on integration and use of all new subsystems will be defined early in the project to maximize the efficiency of both integration and field operations. In addition a series of tailored design reviews are utilized to quickly define the systems and their integration into the DSH configuration. These processes are necessary to ensure activities, such as partially reversing integration of the X-Hab second story of the HDU and deploying and stowing the new work porch for transportation to the JSC Rock Yard and to the Arizona Black Point Lava Flow Site are performed with minimal or no complications. In addition, incremental test operations leading up to an Integrated systems test allows for an orderly systems test program. For FY-11 activities, the HDU DSH will act as a laboratory utilizing a new X-Hab inflatable second floor with crew habitation features. In addition to the day to day operations involving maintenance of the HDU and exploring the surrounding terrain, testing and optimizing the use of the new X-Hab, work porch, Hygiene Module, and other sub-system enhancements will be the focus of the FY-11 test objectives. The HDU team requires a successful integration strategy using a variety of tools and approaches to prepare the DSH for these test objectives. In a challenging environment where the prototyping influences the system design, as well as Vice versa, results of the HDU DSH field tests will influence future designs of habitat systems.

  19. Inspection system qualification and integration into the mask manufacturing environment

    NASA Astrophysics Data System (ADS)

    LaVoy, Rosanne; Fujioka, Ron

    1995-12-01

    Integration of a mask inspection system into a manufacturing environment poses new challenges to both the inspection engineer and the equipment supplier. Traditional specifications (limited primarily to sensitivity and uptime) are no longer sufficient to successfully integrate a system into a 7 by 24 manufacturing area with multiple systems. Issues such as system sensitivity matching, sensitivity characterization by defect type, operator training and certification standards, and real-time SPC control of the systems must be addressed. This paper outlines some of the techniques Intel Mask Operation uses for integration of a new inspection system into the manufacturing line. Specifically moving a beta- site type tool out of the beta-site mode and into volume production. Examples are presented, including installation for manufacturing (including ergonomic modifications), techniques for system-to-system matching, use of SPC charts to monitor system performance, and operator training/certifications. Relationships between system PMs, or other environmental changes, and the system sensitivity SPC control charts also are discussed.

  20. Integrated Compliance Information System (ICIS)

    EPA Pesticide Factsheets

    The purpose of ICIS is to meet evolving Enforcement and Compliance business needs for EPA and State users by integrating information into a single integrated data system that supports both management and programmatic requirements of the Enforcement and Compliance programs.

  1. Using SysML to model complex systems for security.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cano, Lester Arturo

    2010-08-01

    As security systems integrate more Information Technology the design of these systems has tended to become more complex. Some of the most difficult issues in designing Complex Security Systems (CSS) are: Capturing Requirements: Defining Hardware Interfaces: Defining Software Interfaces: Integrating Technologies: Radio Systems: Voice Over IP Systems: Situational Awareness Systems.

  2. Towards G2G: Systems of Technology Database Systems

    NASA Technical Reports Server (NTRS)

    Maluf, David A.; Bell, David

    2005-01-01

    We present an approach and methodology for developing Government-to-Government (G2G) Systems of Technology Database Systems. G2G will deliver technologies for distributed and remote integration of technology data for internal use in analysis and planning as well as for external communications. G2G enables NASA managers, engineers, operational teams and information systems to "compose" technology roadmaps and plans by selecting, combining, extending, specializing and modifying components of technology database systems. G2G will interoperate information and knowledge that is distributed across organizational entities involved that is ideal for NASA future Exploration Enterprise. Key contributions of the G2G system will include the creation of an integrated approach to sustain effective management of technology investments that supports the ability of various technology database systems to be independently managed. The integration technology will comply with emerging open standards. Applications can thus be customized for local needs while enabling an integrated management of technology approach that serves the global needs of NASA. The G2G capabilities will use NASA s breakthrough in database "composition" and integration technology, will use and advance emerging open standards, and will use commercial information technologies to enable effective System of Technology Database systems.

  3. Development and flight test experiences with a flight-crucial digital control system

    NASA Technical Reports Server (NTRS)

    Mackall, Dale A.

    1988-01-01

    Engineers and scientists in the advanced fighter technology integration (AFTI) F-16 program investigated the integration of emerging technologies into an advanced fighter aircraft. AFTI's three major technologies included: flight-crucial digital control, decoupled aircraft flight control, and integration of avionics, flight control, and pilot displays. In addition to investigating improvements in fighter performance, researchers studied the generic problems confronting the designers of highly integrated flight-crucial digital control. An overview is provided of both the advantages and problems of integration digital control systems. Also, an examination of the specification, design, qualification, and flight test life-cycle phase is provided. An overview is given of the fault-tolerant design, multimoded decoupled flight control laws, and integrated avionics design. The approach to qualifying the software and system designs is discussed, and the effects of design choices on system qualification are highlighted.

  4. Integrating the Web and continuous media through distributed objects

    NASA Astrophysics Data System (ADS)

    Labajo, Saul P.; Garcia, Narciso N.

    1998-09-01

    The Web has rapidly grown to become the standard for documents interchange on the Internet. At the same time the interest on transmitting continuous media flows on the Internet, and its associated applications like multimedia on demand, is also growing. Integrating both kinds of systems should allow building real hypermedia systems where all media objects can be linked from any other, taking into account temporal and spatial synchronization. A way to achieve this integration is using the Corba architecture. This is a standard for open distributed systems. There are also recent efforts to integrate Web and Corba systems. We use this architecture to build a service for distribution of data flows endowed with timing restrictions. We use to integrate it with the Web, by one side Java applets that can use the Corba architecture and are embedded on HTML pages. On the other side, we also benefit from the efforts to integrate Corba and the Web.

  5. An optimal policy for a single-vendor and a single-buyer integrated system with setup cost reduction and process-quality improvement

    NASA Astrophysics Data System (ADS)

    Shu, Hui; Zhou, Xideng

    2014-05-01

    The single-vendor single-buyer integrated production inventory system has been an object of study for a long time, but little is known about the effect of investing in reducing setup cost reduction and process-quality improvement for an integrated inventory system in which the products are sold with free minimal repair warranty. The purpose of this article is to minimise the integrated cost by optimising simultaneously the number of shipments and the shipment quantity, the setup cost, and the process quality. An efficient algorithm procedure is proposed for determining the optimal decision variables. A numerical example is presented to illustrate the results of the proposed models graphically. Sensitivity analysis of the model with respect to key parameters of the system is carried out. The paper shows that the proposed integrated model can result in significant savings in the integrated cost.

  6. An integrated photogrammetric and spatial database management system for producing fully structured data using aerial and remote sensing images.

    PubMed

    Ahmadi, Farshid Farnood; Ebadi, Hamid

    2009-01-01

    3D spatial data acquired from aerial and remote sensing images by photogrammetric techniques is one of the most accurate and economic data sources for GIS, map production, and spatial data updating. However, there are still many problems concerning storage, structuring and appropriate management of spatial data obtained using these techniques. According to the capabilities of spatial database management systems (SDBMSs); direct integration of photogrammetric and spatial database management systems can save time and cost of producing and updating digital maps. This integration is accomplished by replacing digital maps with a single spatial database. Applying spatial databases overcomes the problem of managing spatial and attributes data in a coupled approach. This management approach is one of the main problems in GISs for using map products of photogrammetric workstations. Also by the means of these integrated systems, providing structured spatial data, based on OGC (Open GIS Consortium) standards and topological relations between different feature classes, is possible at the time of feature digitizing process. In this paper, the integration of photogrammetric systems and SDBMSs is evaluated. Then, different levels of integration are described. Finally design, implementation and test of a software package called Integrated Photogrammetric and Oracle Spatial Systems (IPOSS) is presented.

  7. Structured approaches to large-scale systems: Variational integrators for interconnected Lagrange-Dirac systems and structured model reduction on Lie groups

    NASA Astrophysics Data System (ADS)

    Parks, Helen Frances

    This dissertation presents two projects related to the structured integration of large-scale mechanical systems. Structured integration uses the considerable differential geometric structure inherent in mechanical motion to inform the design of numerical integration schemes. This process improves the qualitative properties of simulations and becomes especially valuable as a measure of accuracy over long time simulations in which traditional Gronwall accuracy estimates lose their meaning. Often, structured integration schemes replicate continuous symmetries and their associated conservation laws at the discrete level. Such is the case for variational integrators, which discretely replicate the process of deriving equations of motion from variational principles. This results in the conservation of momenta associated to symmetries in the discrete system and conservation of a symplectic form when applicable. In the case of Lagrange-Dirac systems, variational integrators preserve a discrete analogue of the Dirac structure preserved in the continuous flow. In the first project of this thesis, we extend Dirac variational integrators to accommodate interconnected systems. We hope this work will find use in the fields of control, where a controlled system can be thought of as a "plant" system joined to its controller, and in the approach of very large systems, where modular modeling may prove easier than monolithically modeling the entire system. The second project of the thesis considers a different approach to large systems. Given a detailed model of the full system, can we reduce it to a more computationally efficient model without losing essential geometric structures in the system? Asked without the reference to structure, this is the essential question of the field of model reduction. The answer there has been a resounding yes, with Principal Orthogonal Decomposition (POD) with snapshots rising as one of the most successful methods. Our project builds on previous work to extend POD to structured settings. In particular, we consider systems evolving on Lie groups and make use of canonical coordinates in the reduction process. We see considerable improvement in the accuracy of the reduced model over the usual structure-agnostic POD approach.

  8. The Vendors' Corner: Biblio-Techniques' Library and Information System (BLIS).

    ERIC Educational Resources Information Center

    Library Software Review, 1984

    1984-01-01

    Describes online catalog and integrated library computer system designed to enhance Washington Library Network's software. Highlights include system components; implementation options; system features (integrated library functions, database design, system management facilities); support services (installation and training, software maintenance and…

  9. Using Systems Thinking to Frame the Evaluation of a Complex Educational Intervention

    NASA Astrophysics Data System (ADS)

    Kastens, K. A.; Baldassari, C.; DeLisi, J.; Manduca, C. A.

    2014-12-01

    InTeGrate (serc.carleton.edu/integrate/) is the geoscience component of NSF's STEM Talent Expansion Center program. As such, it is a $10M, 5 year effort, with dual goals of improving undergraduate STEM education and addressing an important national challenge, which in InTeGrate's case is environmental sustainability. InTeGrate is very complicated, involving five PI's, dozens of curriculum developers, scores of workshops and webinars, hundreds of faculty, and thousands of students. To get a handle on this complexity, the leadership team and evaluators are viewing project activities and outcomes through a system thinking lens, analogous to how geoscientists view the Earth system. For each major component of the project, we have a flowchart logic model that traces the flows of information, materials, influence, and people that are thought to result from project activities. As is to be expected in a complex system, individual activities are often influenced by multiple inputs and contribute to multiple outputs. The systems approach allows us to spot critical points in the system where evaluative probes are needed; for example, are workshops actually resulting in a flux of new people into roles of increased responsibility within InTeGrate as intended? InTeGrate is permeated with opportunities for participants to engage in assessment, reflection and peer-review. From a systems perspective, this evaluative culture can be seen as an effort to create reinforcing feedback loops for processes that advance InTeGrate's values. For example, assessment team members review draft instructional materials against a materials development rubric and coach developers through an iterative development cycle towards materials that embody InTeGrate's priorities. Of particular interest are flows of information or influence that may carry InTeGrate's impact outward in space and time beyond activities that are directly funded by the project. For example, positive experiences during materials development may influence developers' teaching practice such that they embed InTeGrate's methods into their teaching of non-InTeGrate materials and advocate for InTeGrate methods on their campuses. Only if such influence pathways exist will InTeGrate be able to achieve national and enduring impact.

  10. Fuzzy comprehensive evaluation for grid-connected performance of integrated distributed PV-ES systems

    NASA Astrophysics Data System (ADS)

    Lv, Z. H.; Li, Q.; Huang, R. W.; Liu, H. M.; Liu, D.

    2016-08-01

    Based on the discussion about topology structure of integrated distributed photovoltaic (PV) power generation system and energy storage (ES) in single or mixed type, this paper focuses on analyzing grid-connected performance of integrated distributed photovoltaic and energy storage (PV-ES) systems, and proposes a comprehensive evaluation index system. Then a multi-level fuzzy comprehensive evaluation method based on grey correlation degree is proposed, and the calculations for weight matrix and fuzzy matrix are presented step by step. Finally, a distributed integrated PV-ES power generation system connected to a 380 V low voltage distribution network is taken as the example, and some suggestions are made based on the evaluation results.

  11. Integrated water management system - Description and test results. [for Space Station waste water processing

    NASA Technical Reports Server (NTRS)

    Elden, N. C.; Winkler, H. E.; Price, D. F.; Reysa, R. P.

    1983-01-01

    Water recovery subsystems are being tested at the NASA Lyndon B. Johnson Space Center for Space Station use to process waste water generated from urine and wash water collection facilities. These subsystems are being integrated into a water management system that will incorporate wash water and urine processing through the use of hyperfiltration and vapor compression distillation subsystems. Other hardware in the water management system includes a whole body shower, a clothes washing facility, a urine collection and pretreatment unit, a recovered water post-treatment system, and a water quality monitor. This paper describes the integrated test configuration, pertinent performance data, and feasibility and design compatibility conclusions of the integrated water management system.

  12. A review of integration strategies for solid oxide fuel cells

    NASA Astrophysics Data System (ADS)

    Zhang, Xiongwen; Chan, S. H.; Li, Guojun; Ho, H. K.; Li, Jun; Feng, Zhenping

    Due to increasing oil and gas demand, the depletion of fossil resources, serious global warming, efficient energy systems and new energy conversion processes are urgently needed. Fuel cells and hybrid systems have emerged as advanced thermodynamic systems with great promise in achieving high energy/power efficiency with reduced environmental loads. In particular, due to the synergistic effect of using integrated solid oxide fuel cell (SOFC) and classical thermodynamic cycle technologies, the efficiency of the integrated system can be significantly improved. This paper reviews different concepts/strategies for SOFC-based integration systems, which are timely transformational energy-related technologies available to overcome the threats posed by climate change and energy security.

  13. Positional Accuracy of Airborne Integrated Global Positioning and Inertial Navigation Systems for Mapping in Glen Canyon, Arizona

    USGS Publications Warehouse

    Sanchez, Richard D.; Hothem, Larry D.

    2002-01-01

    High-resolution airborne and satellite image sensor systems integrated with onboard data collection based on the Global Positioning System (GPS) and inertial navigation systems (INS) may offer a quick and cost-effective way to gather accurate topographic map information without ground control or aerial triangulation. The Applanix Corporation?s Position and Orientation Solutions for Direct Georeferencing of aerial photography was used in this project to examine the positional accuracy of integrated GPS/INS for terrain mapping in Glen Canyon, Arizona. The research application in this study yielded important information on the usefulness and limits of airborne integrated GPS/INS data-capture systems for mapping.

  14. Integrated Multi-process Microfluidic Systems for Automating Analysis

    PubMed Central

    Yang, Weichun; Woolley, Adam T.

    2010-01-01

    Microfluidic technologies have been applied extensively in rapid sample analysis. Some current challenges for standard microfluidic systems are relatively high detection limits, and reduced resolving power and peak capacity compared to conventional approaches. The integration of multiple functions and components onto a single platform can overcome these separation and detection limitations of microfluidics. Multiplexed systems can greatly increase peak capacity in multidimensional separations and can increase sample throughput by analyzing many samples simultaneously. On-chip sample preparation, including labeling, preconcentration, cleanup and amplification, can all serve to speed up and automate processes in integrated microfluidic systems. This paper summarizes advances in integrated multi-process microfluidic systems for automated analysis, their benefits and areas for needed improvement. PMID:20514343

  15. A database perspective of the transition from single-use (ancillary-based) systems to integrated models supporting clinical care and research in a MUMPS-based system.

    PubMed

    Siegel, J; Kirkland, D

    1991-01-01

    The Composite Health Care System (CHCS), a MUMPS-based hospital information system (HIS), has evolved from the Decentralized Hospital Computer Program (DHCP) installed within VA Hospitals. The authors explore the evolution of an ancillary-based system toward an integrated model with a look at its current state and possible future. The history and relationships between orders of different types tie specific patient-related data into a logical and temporal model. Diagrams demonstrate how the database structure has evolved to support clinical needs for integration. It is suggested that a fully integrated model is capable of meeting traditional HIS needs.

  16. Human-technology Integration

    NASA Astrophysics Data System (ADS)

    Mullen, Katharine M.

    Human-technology integration is the replacement of human parts and extension of human capabilities with engineered devices and substrates. Its result is hybrid biological-artificial systems. We discuss here four categories of products furthering human-technology integration: wearable computers, pervasive computing environments, engineered tissues and organs, and prosthetics, and introduce examples of currently realized systems in each category. We then note that realization of a completely artificial sytem via the path of human-technology integration presents the prospect of empirical confirmation of an aware artificially embodied system.

  17. Application of remote sensing and Geographic Information Systems to ecosystem-based urban natural resource management

    Treesearch

    Xiaohui Zhang; George Ball; Eve Halper

    2000-01-01

    This paper presents an integrated system to support urban natural resource management. With the application of remote sensing (RS) and geographic information systems (GIS), the paper emphasizes the methodology of integrating information technology and a scientific basis to support ecosystem-based management. First, a systematic integration framework is developed and...

  18. Data Integration in Computer Distributed Systems

    NASA Astrophysics Data System (ADS)

    Kwiecień, Błażej

    In this article the author analyze a problem of data integration in a computer distributed systems. Exchange of information between different levels in integrated pyramid of enterprise process is fundamental with regard to efficient enterprise work. Communication and data exchange between levels are not always the same cause of necessity of different network protocols usage, communication medium, system response time, etc.

  19. Microbiorobots for Manipulation and Sensing

    DTIC Science & Technology

    2016-04-19

    integrated into microscale robotics and biosensor systems. The objective of the proposed program is to develop a platform that integrates bacteria with...information represent enormous potential that can be harnessed and integrated into microscale robotics and biosensor systems. The objective of the...applicable in microscale assembly systems and biosensors that require autonomous coordination of bacteria. (a) Papers published in peer-reviewed

  20. The 10 MWe solar thermal central receiver pilot plant solar facilities design integration, RADL item 1-10

    NASA Astrophysics Data System (ADS)

    1980-07-01

    Accomplishments are reported in the areas of: program management, system integration, the beam characterization system, receiver unit, thermal storage subsystems, master control system, plant support subsystem and engineering services. A solar facilities design integration program action items update is included. Work plan changes and cost underruns are discussed briefly. (LEW)

  1. Social Ecology of Asthma: Engaging Stakeholders in Integrating Health Behavior Theories and Practice-Based Evidence through Systems Mapping

    ERIC Educational Resources Information Center

    Gillen, Emily M.; Hassmiller Lich, Kristen; Yeatts, Karin B.; Hernandez, Michelle L.; Smith, Timothy W.; Lewis, Megan A.

    2014-01-01

    This article describes a process for integrating health behavior and social science theories with practice-based insights using participatory systems thinking and diagramming methods largely inspired by system dynamics methods. This integration can help close the gap between research and practice in health education and health behavior by offering…

  2. Integrating knowledge based functionality in commercial hospital information systems.

    PubMed

    Müller, M L; Ganslandt, T; Eich, H P; Lang, K; Ohmann, C; Prokosch, H U

    2000-01-01

    Successful integration of knowledge-based functions in the electronic patient record depends on direct and context-sensitive accessibility and availability to clinicians and must suit their workflow. In this paper we describe an exemplary integration of an existing standalone scoring system for acute abdominal pain into two different commercial hospital information systems using Java/Corba technolgy.

  3. Educational Systems Integrators/Integrated Learning System Project: Titan Schools 1993-94. OER Report.

    ERIC Educational Resources Information Center

    New York City Board of Education, Brooklyn, NY. Office of Educational Research.

    The 1993-94 Integrated Learning System (ILS) project, a means of delivering individualized instruction through a computer network, involved approximately 70 schools from New York City school districts. To help schools learn about and operate the technology in an ILS, districts were given the option of hiring one of the following companies…

  4. Integrated Electronic Warfare Systems Aboard the United States Navy 21st Century Warship

    DTIC Science & Technology

    2009-12-01

    automated operation using a Human-In-the-Loop that could be integrated into existing and future combat systems. A model was developed that demonstrates...complete range of automated operation using a Human-In-the-Loop that could be integrated into existing and future combat systems. A model was developed...44 1. Base Case Model

  5. Integrated delivery systems focus on service delivery after capitation efforts stall.

    PubMed

    2005-03-01

    Integrated delivery systems focus on service delivery after capitation efforts stall. Integrated delivery systems are going through changes that are focusing the provider organizations more on delivering care than managing risk, says Dean C. Coddington, one of the leading researchers into capitated organizations and a senior consultant with McManis Consulting in Denver.

  6. CAI: A Model for the Comparison and Selection of Integrated Learning Systems in Large School Districts.

    ERIC Educational Resources Information Center

    Resta, Paul E.; Rost, Paul

    The Albuquerque (New Mexico) Public Schools conducted a three-year study of integrated computer-based learning systems, including WICAT, Dolphin, PLATO, CCC, and DEGEM. Through cooperation with the Education Consolidation Improvement Act Chapter 1 program, four large integrated learning systems (ILS) were purchased and studied. They were installed…

  7. Development of Integrated Programs for Aerospace-Vehicle Design (IPAD)

    NASA Technical Reports Server (NTRS)

    Anderson, O. L.; Calvery, A. L.; Davis, D. A.; Dickmann, L.; Folger, D. H.; Jochem, E. N.; Kitto, C. M.; Vonlimbach, G.

    1977-01-01

    Integrated Programs for Aerospace Vehicle Design (IPAD) system design requirements are given. The information is based on the IPAD User Requirements Document (D6-IPAD-70013-D) and the Integrated Information Processing Requirements Document (D6-IPAD-70012-D). General information about IPAD and a list of the system design requirements that are to be satisfied by the IPAD system are given. The system design requirements definition is to be considered as a baseline definition of the IPAD system design requirements.

  8. Parallel Architectures and Parallel Algorithms for Integrated Vision Systems. Ph.D. Thesis

    NASA Technical Reports Server (NTRS)

    Choudhary, Alok Nidhi

    1989-01-01

    Computer vision is regarded as one of the most complex and computationally intensive problems. An integrated vision system (IVS) is a system that uses vision algorithms from all levels of processing to perform for a high level application (e.g., object recognition). An IVS normally involves algorithms from low level, intermediate level, and high level vision. Designing parallel architectures for vision systems is of tremendous interest to researchers. Several issues are addressed in parallel architectures and parallel algorithms for integrated vision systems.

  9. Integration between terrestrial-based and satellite-based land mobile communications systems

    NASA Technical Reports Server (NTRS)

    Arcidiancono, Antonio

    1990-01-01

    A survey is given of several approaches to improving the performance and marketability of mobile satellite systems (MSS). The provision of voice/data services in the future regional European Land Mobile Satellite System (LMSS), network integration between the Digital Cellular Mobile System (GSM) and LMSS, the identification of critical areas for the implementation of integrated GSM/LMSS areas, space segment scenarios, LMSS for digital trunked private mobile radio (PMR) services, and code division multiple access (CDMA) techniques for a terrestrial/satellite system are covered.

  10. ISSYS: An integrated synergistic Synthesis System

    NASA Technical Reports Server (NTRS)

    Dovi, A. R.

    1980-01-01

    Integrated Synergistic Synthesis System (ISSYS), an integrated system of computer codes in which the sequence of program execution and data flow is controlled by the user, is discussed. The commands available to exert such control, the ISSYS major function and rules, and the computer codes currently available in the system are described. Computational sequences frequently used in the aircraft structural analysis and synthesis are defined. External computer codes utilized by the ISSYS system are documented. A bibliography on the programs is included.

  11. Turnkey CAD/CAM systems' integration with IPAD systems

    NASA Technical Reports Server (NTRS)

    Blauth, R. E.

    1980-01-01

    Today's commercially available turnkey CAD/CAM systems provide a highly interactive environment, and support many specialized application functions for the design/drafting/manufacturing process. This paper presents an overview of several aerospace companies which have successfully integrated turnkey CAD/CAM systems with their own company wide engineering and manufacturing systems. It also includes a vendor's view of the benefits as well as the disadvantages of such integration efforts. Specific emphasis is placed upon the selection of standards for representing geometric engineering data and for communicating such information between different CAD/CAM systems.

  12. Integrated multiplexed capillary electrophoresis system

    DOEpatents

    Yeung, Edward S.; Tan, Hongdong

    2002-05-14

    The present invention provides an integrated multiplexed capillary electrophoresis system for the analysis of sample analytes. The system integrates and automates multiple components, such as chromatographic columns and separation capillaries, and further provides a detector for the detection of analytes eluting from the separation capillaries. The system employs multiplexed freeze/thaw valves to manage fluid flow and sample movement. The system is computer controlled and is capable of processing samples through reaction, purification, denaturation, pre-concentration, injection, separation and detection in parallel fashion. Methods employing the system of the invention are also provided.

  13. The Performance Analysis of a Real-Time Integrated INS/GPS Vehicle Navigation System with Abnormal GPS Measurement Elimination

    PubMed Central

    Chiang, Kai-Wei; Duong, Thanh Trung; Liao, Jhen-Kai

    2013-01-01

    The integration of an Inertial Navigation System (INS) and the Global Positioning System (GPS) is common in mobile mapping and navigation applications to seamlessly determine the position, velocity, and orientation of the mobile platform. In most INS/GPS integrated architectures, the GPS is considered to be an accurate reference with which to correct for the systematic errors of the inertial sensors, which are composed of biases, scale factors and drift. However, the GPS receiver may produce abnormal pseudo-range errors mainly caused by ionospheric delay, tropospheric delay and the multipath effect. These errors degrade the overall position accuracy of an integrated system that uses conventional INS/GPS integration strategies such as loosely coupled (LC) and tightly coupled (TC) schemes. Conventional tightly coupled INS/GPS integration schemes apply the Klobuchar model and the Hopfield model to reduce pseudo-range delays caused by ionospheric delay and tropospheric delay, respectively, but do not address the multipath problem. However, the multipath effect (from reflected GPS signals) affects the position error far more significantly in a consumer-grade GPS receiver than in an expensive, geodetic-grade GPS receiver. To avoid this problem, a new integrated INS/GPS architecture is proposed. The proposed method is described and applied in a real-time integrated system with two integration strategies, namely, loosely coupled and tightly coupled schemes, respectively. To verify the effectiveness of the proposed method, field tests with various scenarios are conducted and the results are compared with a reliable reference system. PMID:23955434

  14. 48 CFR 352.234-1 - Notice of earned value management system-pre-award Integrated Baseline Review.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... management system-pre-award Integrated Baseline Review. 352.234-1 Section 352.234-1 Federal Acquisition... Texts of Provisions and Clauses 352.234-1 Notice of earned value management system—pre-award Integrated... provision: Notice of Earned Value Management System—Pre-Award Integrated Baseline Review (October 2008) The...

  15. 48 CFR 352.234-2 - Notice of earned value management system-post-award Integrated Baseline Review.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... management system-post-award Integrated Baseline Review. 352.234-2 Section 352.234-2 Federal Acquisition... Texts of Provisions and Clauses 352.234-2 Notice of earned value management system—post-award Integrated... provision: Notice of Earned Value Management System—Post-Award Integrated Baseline Review (October 2008) (a...

  16. 48 CFR 352.234-2 - Notice of earned value management system-post-award Integrated Baseline Review.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... management system-post-award Integrated Baseline Review. 352.234-2 Section 352.234-2 Federal Acquisition... Texts of Provisions and Clauses 352.234-2 Notice of earned value management system—post-award Integrated... provision: Notice of Earned Value Management System—Post-Award Integrated Baseline Review (October 2008) (a...

  17. 48 CFR 352.234-2 - Notice of earned value management system-post-award Integrated Baseline Review.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... management system-post-award Integrated Baseline Review. 352.234-2 Section 352.234-2 Federal Acquisition... Texts of Provisions and Clauses 352.234-2 Notice of earned value management system—post-award Integrated... provision: Notice of Earned Value Management System—Post-Award Integrated Baseline Review (October 2008) (a...

  18. 48 CFR 352.234-1 - Notice of earned value management system-pre-award Integrated Baseline Review.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... management system-pre-award Integrated Baseline Review. 352.234-1 Section 352.234-1 Federal Acquisition... Texts of Provisions and Clauses 352.234-1 Notice of earned value management system—pre-award Integrated... provision: Notice of Earned Value Management System—Pre-Award Integrated Baseline Review (October 2008) The...

  19. 48 CFR 352.234-1 - Notice of earned value management system-pre-award Integrated Baseline Review.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... management system-pre-award Integrated Baseline Review. 352.234-1 Section 352.234-1 Federal Acquisition... Texts of Provisions and Clauses 352.234-1 Notice of earned value management system—pre-award Integrated... provision: Notice of Earned Value Management System—Pre-Award Integrated Baseline Review (October 2008) The...

  20. 48 CFR 352.234-2 - Notice of earned value management system-post-award Integrated Baseline Review.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... management system-post-award Integrated Baseline Review. 352.234-2 Section 352.234-2 Federal Acquisition... Texts of Provisions and Clauses 352.234-2 Notice of earned value management system—post-award Integrated... provision: Notice of Earned Value Management System—Post-Award Integrated Baseline Review (October 2008) (a...

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