Information integration in health care organizations: The case of a European health system.

PubMed

Calciolari, Stefano; Buccoliero, Luca

2010-01-01

Information system integration is an important dimension of a company's information system maturity and plays a relevant role in meeting information needs and accountability targets. However, no generalizable evidence exists about whether and how the main integrating technologies influence information system integration in health care organizations. This study examined how integrating technologies are adopted in public health care organizations and chief information officers' (CIOs) perceptions about their influence on information system integration. We used primary data on integrating technologies' adoption and CIOs' perception regarding information system integration in public health care organizations. Analysis of variance (ANOVA) and multinomial logistic regression were used to examine the relationship between CIOs' perception about information system integration and the adopted technologies. Data from 90 health care organizations were available for analyses. Integrating technologies are relatively diffused in public health care organizations, and CIOs seem to shape information system toward integrated architectures. There is a significant positive (although modest, .3) correlation between the number of integrating technologies adopted and the CIO's satisfaction with them. However, regression analysis suggests that organizations covering a broader spectrum of these technologies are less likely to have their CIO reporting main problems concerning integration in the administrative area of the information system compared with the clinical area and where the two areas overlap. Integrating technologies are associated with less perceived problems in the information system administrative area rather than in other areas. Because CIOs play the role of information resource allocators, by influencing information system toward integrated architecture, health care organization leaders should foster cooperation between CIOs and medical staff to enhance information system integration.

1991 NASA Life Support Systems Analysis workshop

NASA Technical Reports Server (NTRS)

Evanich, Peggy L.; Crabb, Thomas M.; Gartrell, Charles F.

1992-01-01

The 1991 Life Support Systems Analysis Workshop was sponsored by NASA Headquarters' Office of Aeronautics and Space Technology (OAST) to foster communication among NASA, industrial, and academic specialists, and to integrate their inputs and disseminate information to them. The overall objective of systems analysis within the Life Support Technology Program of OAST is to identify, guide the development of, and verify designs which will increase the performance of the life support systems on component, subsystem, and system levels for future human space missions. The specific goals of this workshop were to report on the status of systems analysis capabilities, to integrate the chemical processing industry technologies, and to integrate recommendations for future technology developments related to systems analysis for life support systems. The workshop included technical presentations, discussions, and interactive planning, with time allocated for discussion of both technology status and time-phased technology development recommendations. Key personnel from NASA, industry, and academia delivered inputs and presentations on the status and priorities of current and future systems analysis methods and requirements.

Thermoeconomic analysis of an integrated multi-effect desalination thermal vapor compression (MED-TVC) system with a trigeneration system using triple-pressure HRSG

NASA Astrophysics Data System (ADS)

Ghaebi, Hadi; Abbaspour, Ghader

2018-05-01

In this research, thermoeconomic analysis of a multi-effect desalination thermal vapor compression (MED-TVC) system integrated with a trigeneration system with a gas turbine prime mover is carried out. The integrated system comprises of a compressor, a combustion chamber, a gas turbine, a triple-pressure (low, medium and high pressures) heat recovery steam generator (HRSG) system, an absorption chiller cycle (ACC), and a multi-effect desalination (MED) system. Low pressure steam produced in the HRSG is used to drive absorption chiller cycle, medium pressure is used in desalination system and high pressure superheated steam is used for heating purposes. For thermodynamic and thermoeconomic analysis of the proposed integrated system, Engineering Equation Solver (EES) is used by employing mass, energy, exergy, and cost balance equations for each component of system. The results of the modeling showed that with the new design, the exergy efficiency in the base design will increase to 57.5%. In addition, thermoeconomic analysis revealed that the net power, heating, fresh water and cooling have the highest production cost, respectively.

Integrating forest inventory and analysis data into a LIDAR-based carbon monitoring system

Treesearch

Kristofer D. Johnson; Richard Birdsey; Andrew O Finley; Anu Swantaran; Ralph Dubayah; Craig Wayson; Rachel Riemann

2014-01-01

Forest Inventory and Analysis (FIA) data may be a valuable component of a LIDAR-based carbon monitoring system, but integration of the two observation systems is not without challenges. To explore integration methods, two wall-to-wall LIDAR-derived biomass maps were compared to FIA data at both the plot and county levels in Anne Arundel and Howard Counties in Maryland...

Benefit-Cost Analysis of Integrated Paratransit Systems : Volume 3. Scenario Analysis.

DOT National Transportation Integrated Search

1979-09-01

This is the third volume of a six-volume report documenting the results of a study entitled "Benefit-Cost Analysis of Integrated Paratransit Systems." This volume provides detailed results of a series of scenario analyses designed to determine the im...

Aviation Data Integration System

NASA Technical Reports Server (NTRS)

Kulkarni, Deepak; Wang, Yao; Windrem, May; Patel, Hemil; Keller, Richard

2003-01-01

During the analysis of flight data and safety reports done in ASAP and FOQA programs, airline personnel are not able to access relevant aviation data for a variety of reasons. We have developed the Aviation Data Integration System (ADIS), a software system that provides integrated heterogeneous data to support safety analysis. Types of data available in ADIS include weather, D-ATIS, RVR, radar data, and Jeppesen charts, and flight data. We developed three versions of ADIS to support airlines. The first version has been developed to support ASAP teams. A second version supports FOQA teams, and it integrates aviation data with flight data while keeping identification information inaccessible. Finally, we developed a prototype that demonstrates the integration of aviation data into flight data analysis programs. The initial feedback from airlines is that ADIS is very useful in FOQA and ASAP analysis.

Collaboration and Synergy among Government, Industry and Academia in M&S Domain: Turkey’s Approach

DTIC Science & Technology

2009-10-01

Analysis, Decision Support System Design and Implementation, Simulation Output Analysis, Statistical Data Analysis, Virtual Reality , Artificial... virtual and constructive visual simulation systems as well as integrated advanced analytical models. Collaboration and Synergy among Government...simulation systems that are ready to use, credible, integrated with C4ISR systems.  Creating synthetic environments and/or virtual prototypes of concepts

Timing of Formal Phase Safety Reviews for Large-Scale Integrated Hazard Analysis

NASA Technical Reports Server (NTRS)

Massie, Michael J.; Morris, A. Terry

2010-01-01

Integrated hazard analysis (IHA) is a process used to identify and control unacceptable risk. As such, it does not occur in a vacuum. IHA approaches must be tailored to fit the system being analyzed. Physical, resource, organizational and temporal constraints on large-scale integrated systems impose additional direct or derived requirements on the IHA. The timing and interaction between engineering and safety organizations can provide either benefits or hindrances to the overall end product. The traditional approach for formal phase safety review timing and content, which generally works well for small- to moderate-scale systems, does not work well for very large-scale integrated systems. This paper proposes a modified approach to timing and content of formal phase safety reviews for IHA. Details of the tailoring process for IHA will describe how to avoid temporary disconnects in major milestone reviews and how to maintain a cohesive end-to-end integration story particularly for systems where the integrator inherently has little to no insight into lower level systems. The proposal has the advantage of allowing the hazard analysis development process to occur as technical data normally matures.

Acquisition of an Advanced Thermal Analysis andImaging System for Integration with Interdisciplinary Researchand Education in Low Density Organic Inorganic Materials

DTIC Science & Technology

2017-12-02

Report: Acquisition of an Advanced Thermal Analysis and Imaging System for Integration with Interdisciplinary Research and Education in Low Density...for Integration with Interdisciplinary Research and Education in Low Density Organic-Inorganic Materials Report Term: 0-Other Email: dmisra2

Risk Interfaces to Support Integrated Systems Analysis and Development

NASA Technical Reports Server (NTRS)

Mindock, Jennifer; Lumpkins, Sarah; Shelhamer, Mark; Anton, Wilma; Havenhill, Maria

2016-01-01

Objectives for systems analysis capability: Develop integrated understanding of how a complex human physiological-socio-technical mission system behaves in spaceflight. Why? Support development of integrated solutions that prevent unwanted outcomes (Implementable approaches to minimize mission resources(mass, power, crew time, etc.)); Support development of tools for autonomy (need for exploration) (Assess and maintain resilience -individuals, teams, integrated system). Output of this exercise: -Representation of interfaces based on Human System Risk Board (HSRB) Risk Summary information and simple status based on Human Research Roadmap; Consolidated HSRB information applied to support communication; Point-of-Departure for HRP Element planning; Ability to track and communicate status of collaborations. 4

Detailed requirements document for the integrated structural analysis system, phase B

NASA Technical Reports Server (NTRS)

Rainey, J. A.

1976-01-01

The requirements are defined for a software system entitled integrated Structural Analysis System (ISAS) Phase B which is being developed to provide the user with a tool by which a complete and detailed analysis of a complex structural system can be performed. This software system will allow for automated interface with numerous structural analysis batch programs and for user interaction in the creation, selection, and validation of data. This system will include modifications to the 4 functions developed for ISAS, and the development of 25 new functions. The new functions are described.

Energy Analysis Research | Energy Analysis | NREL

Science.gov Websites

innovation through integration. Illustration of NREL energy analysis research, including impact systems analysis integrates all aspects of our capability set to develop future energy system scenarios evaluate and understand the impact of markets, policies, and financing on technology uptake and the impact

Integrating Reliability Analysis with a Performance Tool

NASA Technical Reports Server (NTRS)

Nicol, David M.; Palumbo, Daniel L.; Ulrey, Michael

1995-01-01

A large number of commercial simulation tools support performance oriented studies of complex computer and communication systems. Reliability of these systems, when desired, must be obtained by remodeling the system in a different tool. This has obvious drawbacks: (1) substantial extra effort is required to create the reliability model; (2) through modeling error the reliability model may not reflect precisely the same system as the performance model; (3) as the performance model evolves one must continuously reevaluate the validity of assumptions made in that model. In this paper we describe an approach, and a tool that implements this approach, for integrating a reliability analysis engine into a production quality simulation based performance modeling tool, and for modeling within such an integrated tool. The integrated tool allows one to use the same modeling formalisms to conduct both performance and reliability studies. We describe how the reliability analysis engine is integrated into the performance tool, describe the extensions made to the performance tool to support the reliability analysis, and consider the tool's performance.

Fault tree analysis for integrated and probabilistic risk analysis of drinking water systems.

PubMed

Lindhe, Andreas; Rosén, Lars; Norberg, Tommy; Bergstedt, Olof

2009-04-01

Drinking water systems are vulnerable and subject to a wide range of risks. To avoid sub-optimisation of risk-reduction options, risk analyses need to include the entire drinking water system, from source to tap. Such an integrated approach demands tools that are able to model interactions between different events. Fault tree analysis is a risk estimation tool with the ability to model interactions between events. Using fault tree analysis on an integrated level, a probabilistic risk analysis of a large drinking water system in Sweden was carried out. The primary aims of the study were: (1) to develop a method for integrated and probabilistic risk analysis of entire drinking water systems; and (2) to evaluate the applicability of Customer Minutes Lost (CML) as a measure of risk. The analysis included situations where no water is delivered to the consumer (quantity failure) and situations where water is delivered but does not comply with water quality standards (quality failure). Hard data as well as expert judgements were used to estimate probabilities of events and uncertainties in the estimates. The calculations were performed using Monte Carlo simulations. CML is shown to be a useful measure of risks associated with drinking water systems. The method presented provides information on risk levels, probabilities of failure, failure rates and downtimes of the system. This information is available for the entire system as well as its different sub-systems. Furthermore, the method enables comparison of the results with performance targets and acceptable levels of risk. The method thus facilitates integrated risk analysis and consequently helps decision-makers to minimise sub-optimisation of risk-reduction options.

Integrated Formulation of Beacon-Based Exception Analysis for Multimissions

NASA Technical Reports Server (NTRS)

Mackey, Ryan; James, Mark; Park, Han; Zak, Mickail

2003-01-01

Further work on beacon-based exception analysis for multimissions (BEAM), a method of real-time, automated diagnosis of a complex electromechanical systems, has greatly expanded its capability and suitability of application. This expanded formulation, which fully integrates physical models and symbolic analysis, is described. The new formulation of BEAM expands upon previous advanced techniques for analysis of signal data, utilizing mathematical modeling of the system physics, and expert-system reasoning,

Probabilistic structural analysis methods for select space propulsion system components

NASA Technical Reports Server (NTRS)

Millwater, H. R.; Cruse, T. A.

1989-01-01

The Probabilistic Structural Analysis Methods (PSAM) project developed at the Southwest Research Institute integrates state-of-the-art structural analysis techniques with probability theory for the design and analysis of complex large-scale engineering structures. An advanced efficient software system (NESSUS) capable of performing complex probabilistic analysis has been developed. NESSUS contains a number of software components to perform probabilistic analysis of structures. These components include: an expert system, a probabilistic finite element code, a probabilistic boundary element code and a fast probability integrator. The NESSUS software system is shown. An expert system is included to capture and utilize PSAM knowledge and experience. NESSUS/EXPERT is an interactive menu-driven expert system that provides information to assist in the use of the probabilistic finite element code NESSUS/FEM and the fast probability integrator (FPI). The expert system menu structure is summarized. The NESSUS system contains a state-of-the-art nonlinear probabilistic finite element code, NESSUS/FEM, to determine the structural response and sensitivities. A broad range of analysis capabilities and an extensive element library is present.

Computer-aided-engineering system for modeling and analysis of ECLSS integration testing

NASA Technical Reports Server (NTRS)

Sepahban, Sonbol

1987-01-01

The accurate modeling and analysis of two-phase fluid networks found in environmental control and life support systems is presently undertaken by computer-aided engineering (CAE) techniques whose generalized fluid dynamics package can solve arbitrary flow networks. The CAE system for integrated test bed modeling and analysis will also furnish interfaces and subsystem/test-article mathematical models. Three-dimensional diagrams of the test bed are generated by the system after performing the requisite simulation and analysis.

Hybrid diagnostic system: beacon-based exception analysis for multimissions - Livingstone integration

NASA Technical Reports Server (NTRS)

Park, Han G.; Cannon, Howard; Bajwa, Anupa; Mackey, Ryan; James, Mark; Maul, William

2004-01-01

This paper describes the initial integration of a hybrid reasoning system utilizing a continuous domain feature-based detector, Beacon-based Exceptions Analysis for Multimissions (BEAM), and a discrete domain model-based reasoner, Livingstone.

A Software Tool for Integrated Optical Design Analysis

NASA Technical Reports Server (NTRS)

Moore, Jim; Troy, Ed; DePlachett, Charles; Montgomery, Edward (Technical Monitor)

2001-01-01

Design of large precision optical systems requires multi-disciplinary analysis, modeling, and design. Thermal, structural and optical characteristics of the hardware must be accurately understood in order to design a system capable of accomplishing the performance requirements. The interactions between each of the disciplines become stronger as systems are designed lighter weight for space applications. This coupling dictates a concurrent engineering design approach. In the past, integrated modeling tools have been developed that attempt to integrate all of the complex analysis within the framework of a single model. This often results in modeling simplifications and it requires engineering specialist to learn new applications. The software described in this presentation addresses the concurrent engineering task using a different approach. The software tool, Integrated Optical Design Analysis (IODA), uses data fusion technology to enable a cross discipline team of engineering experts to concurrently design an optical system using their standard validated engineering design tools.

Integrated analysis of large space systems

NASA Technical Reports Server (NTRS)

Young, J. P.

1980-01-01

Based on the belief that actual flight hardware development of large space systems will necessitate a formalized method of integrating the various engineering discipline analyses, an efficient highly user oriented software system capable of performing interdisciplinary design analyses with tolerable solution turnaround time is planned Specific analysis capability goals were set forth with initial emphasis given to sequential and quasi-static thermal/structural analysis and fully coupled structural/control system analysis. Subsequently, the IAC would be expanded to include a fully coupled thermal/structural/control system, electromagnetic radiation, and optical performance analyses.

Integrated Safety Analysis Teams

NASA Technical Reports Server (NTRS)

Wetherholt, Jonathan C.

2008-01-01

Today's complex systems require understanding beyond one person s capability to comprehend. Each system requires a team to divide the system into understandable subsystems which can then be analyzed with an Integrated Hazard Analysis. The team must have both specific experiences and diversity of experience. Safety experience and system understanding are not always manifested in one individual. Group dynamics make the difference between success and failure as well as the difference between a difficult task and a rewarding experience. There are examples in the news which demonstrate the need to connect the pieces of a system into a complete picture. The Columbia disaster is now a standard example of a low consequence hazard in one part of the system; the External Tank is a catastrophic hazard cause for a companion subsystem, the Space Shuttle Orbiter. The interaction between the hardware, the manufacturing process, the handling, and the operations contributed to the problem. Each of these had analysis performed, but who constituted the team which integrated this analysis together? This paper will explore some of the methods used for dividing up a complex system; and how one integration team has analyzed the parts. How this analysis has been documented in one particular launch space vehicle case will also be discussed.

Management/Technical Interaction in Integrated Information System Development.

ERIC Educational Resources Information Center

Bagley, Clarence H.; Gardner, Don E.

The integrated information system element of the management information system concept has practical applications for management in the areas of both information analysis and decision-model building. Four basic options for achieving integration in operational data systems are: a default option, the coordinated file option, the distributed…

Man-Machine Integrated Design and Analysis System (MIDAS): Functional Overview

NASA Technical Reports Server (NTRS)

Corker, Kevin; Neukom, Christian

1998-01-01

Included in the series of screen print-outs illustrates the structure and function of the Man-Machine Integrated Design and Analysis System (MIDAS). Views into the use of the system and editors are featured. The use-case in this set of graphs includes the development of a simulation scenario.

Integrated multidisciplinary analysis tool IMAT users' guide

NASA Technical Reports Server (NTRS)

Meissner, Frances T. (Editor)

1988-01-01

The Integrated Multidisciplinary Analysis Tool (IMAT) is a computer software system developed at Langley Research Center. IMAT provides researchers and analysts with an efficient capability to analyze satellite controls systems influenced by structural dynamics. Using a menu-driven executive system, IMAT leads the user through the program options. IMAT links a relational database manager to commercial and in-house structural and controls analysis codes. This paper describes the IMAT software system and how to use it.

Study of component technologies for fuel cell on-site integrated energy system. Volume 2: Appendices

NASA Technical Reports Server (NTRS)

Lee, W. D.; Mathias, S.

1980-01-01

This data base catalogue was compiled in order to facilitate the analysis of various on site integrated energy system with fuel cell power plants. The catalogue is divided into two sections. The first characterizes individual components in terms of their performance profiles as a function of design parameters. The second characterizes total heating and cooling systems in terms of energy output as a function of input and control variables. The integrated fuel cell systems diagrams and the computer analysis of systems are included as well as the cash flows series for baseline systems.

Integrated dynamic analysis simulation of space stations with controllable solar arrays (supplemental data and analyses)

NASA Technical Reports Server (NTRS)

Heinrichs, J. A.; Fee, J. J.

1972-01-01

Space station and solar array data and the analyses which were performed in support of the integrated dynamic analysis study. The analysis methods and the formulated digital simulation were developed. Control systems for space station altitude control and solar array orientation control include generic type control systems. These systems have been digitally coded and included in the simulation.

Preliminary analysis of an integrated logistics system for OSSA payloads

NASA Technical Reports Server (NTRS)

Palguta, T.; Bradley, W.; Stockton, T.

1988-01-01

The results of studies of the Office of Space Science and Applications' (OSSA) need for an integrated logistics system to support OSSA payloads, whether attached to the Space Station or free-flying are detailed. An executive summary, the integrated logistics support strategy, preparation of planning documents and a supportability analysis of the 1.8 meter centrifuge are discussed.

Cost-effectiveness of integrated analysis/design systems /IPAD/ An executive summary. II. [for aerospace vehicles

NASA Technical Reports Server (NTRS)

Miller, R. E., Jr.; Hansen, S. D.; Redhed, D. D.; Southall, J. W.; Kawaguchi, A. S.

1974-01-01

Evaluation of the cost-effectiveness of integrated analysis/design systems with particular attention to Integrated Program for Aerospace-Vehicle Design (IPAD) project. An analysis of all the ingredients of IPAD indicates the feasibility of a significant cost and flowtime reduction in the product design process involved. It is also concluded that an IPAD-supported design process will provide a framework for configuration control, whereby the engineering costs for design, analysis and testing can be controlled during the air vehicle development cycle.

Integrated vehicle-based safety systems (IVBSS) : light vehicle platform field operational test data analysis plan.

DOT National Transportation Integrated Search

2009-12-22

This document presents the University of Michigan Transportation Research Institutes plan to : perform analysis of data collected from the light vehicle platform field operational test of the : Integrated Vehicle-Based Safety Systems (IVBSS) progr...

Integrated vehicle-based safety systems (IVBSS) : heavy truck platform field operational test data analysis plan.

DOT National Transportation Integrated Search

2009-11-23

This document presents the University of Michigan Transportation Research Institutes plan to perform : analysis of data collected from the heavy truck platform field operational test of the Integrated Vehicle- : Based Safety Systems (IVBSS) progra...

IPAD applications to the design, analysis, and/or machining of aerospace structures. [Integrated Program for Aerospace-vehicle Design

NASA Technical Reports Server (NTRS)

Blackburn, C. L.; Dovi, A. R.; Kurtze, W. L.; Storaasli, O. O.

1981-01-01

A computer software system for the processing and integration of engineering data and programs, called IPAD (Integrated Programs for Aerospace-Vehicle Design), is described. The ability of the system to relieve the engineer of the mundane task of input data preparation is demonstrated by the application of a prototype system to the design, analysis, and/or machining of three simple structures. Future work to further enhance the system's automated data handling and ability to handle larger and more varied design problems are also presented.

Mesoscale and severe storms (Mass) data management and analysis system

NASA Technical Reports Server (NTRS)

Hickey, J. S.; Karitani, S.; Dickerson, M.

1984-01-01

Progress on the Mesoscale and Severe Storms (MASS) data management and analysis system is described. An interactive atmospheric data base management software package to convert four types of data (Sounding, Single Level, Grid, Image) into standard random access formats is implemented and integrated with the MASS AVE80 Series general purpose plotting and graphics display data analysis software package. An interactive analysis and display graphics software package (AVE80) to analyze large volumes of conventional and satellite derived meteorological data is enhanced to provide imaging/color graphics display utilizing color video hardware integrated into the MASS computer system. Local and remote smart-terminal capability is provided by installing APPLE III computer systems within individual scientist offices and integrated with the MASS system, thus providing color video display, graphics, and characters display of the four data types.

A computer-aided movement analysis system.

PubMed

Fioretti, S; Leo, T; Pisani, E; Corradini, M L

1990-08-01

Interaction with biomechanical data concerning human movement analysis implies the adoption of various experimental equipments and the choice of suitable models, data processing, and graphical data restitution techniques. The integration of measurement setups with the associated experimental protocols and the relative software procedures constitutes a computer-aided movement analysis (CAMA) system. In the present paper such integration is mapped onto the causes that limit the clinical acceptance of movement analysis methods. The structure of the system is presented. A specific CAMA system devoted to posture analysis is described in order to show the attainable features. Scientific results obtained with the support of the described system are also reported.

Integrated corridor management initiative : demonstration phase evaluation - Dallas decision support system analysis test plan.

DOT National Transportation Integrated Search

2012-08-01

This report presents the test plan for conducting the Decision Support System (DSS) Analysis for the United States Department of Transportation (U.S. DOT) evaluation of the Dallas U.S. 75 Integrated Corridor Management (ICM) Initiative Demonstration....

Electromagnetic Fields Exposure Limits

DTIC Science & Technology

2018-01-01

analysis, synthesis, integration and validation of knowledge derived through the scientific method. In NATO, S&T is addressed using different...Panel • NMSG NATO Modelling and Simulation Group • SAS System Analysis and Studies Panel • SCI Systems Concepts and Integration Panel • SET... integrity or morphology. They later also failed to find a lack of direct DNA damage in human blood (strand breaks, alkali-labile sites, and incomplete

Proceedings of the NASTRAN (Tradename) Users’ Colloquium (14th) Held in San Diego, California on 5-9 May 1986

DTIC Science & Technology

1986-05-01

4. Bossi, J. A., Price, G. A., and Winkleblack, S. A., " Flexible Spacecraft Controller Design Using the Integrated Analysis Capability (IAC)," AIAA...P., "Integrated Control System Design Capabilities at the Goddard Space Flight Center," Pro- ceedings of the 2nd IEEE Control Systems Society...Symposium on Computer- Aided Control System Design (CACSD), Santa Barbara, California, March, 13-15 1985. 6. Frisch, H. P. "Integrated Analysis Capability

Integration of electrochemistry in micro-total analysis systems for biochemical assays: recent developments.

PubMed

Xu, Xiaoli; Zhang, Song; Chen, Hui; Kong, Jilie

2009-11-15

Micro-total analysis systems (microTAS) integrate different analytical operations like sample preparation, separation and detection into a single microfabricated device. With the outstanding advantages of low cost, satisfactory analytical efficiency and flexibility in design, highly integrated and miniaturized devices from the concept of microTAS have gained widespread applications, especially in biochemical assays. Electrochemistry is shown to be quite compatible with microanalytical systems for biochemical assays, because of its attractive merits such as simplicity, rapidity, high sensitivity, reduced power consumption, and sample/reagent economy. This review presents recent developments in the integration of electrochemistry in microdevices for biochemical assays. Ingenious microelectrode design and fabrication methods, and versatility of electrochemical techniques are involved. Practical applications of such integrated microsystem in biochemical assays are focused on in situ analysis, point-of-care testing and portable devices. Electrochemical techniques are apparently suited to microsystems, since easy microfabrication of electrochemical elements and a high degree of integration with multi-analytical functions can be achieved at low cost. Such integrated microsystems will play an increasingly important role for analysis of small volume biochemical samples. Work is in progress toward new microdevice design and applications.

Exploration of the integration of care for persons with a traumatic brain injury using social network analysis methodology.

PubMed

Lamontagne, Marie-Eve

2013-01-01

Integration is a popular strategy to increase the quality of care within systems of care. However, there is no common language, approach or tool allowing for a valid description, comparison and evaluation of integrated care. Social network analysis could be a viable methodology to provide an objective picture of integrated networks. To illustrate social network analysis use in the context of systems of care for traumatic brain injury. We surveyed members of a network using a validated questionnaire to determine the links between them. We determined the density, centrality, multiplexity, and quality of the links reported. The network was described as moderately dense (0.6), the most prevalent link was knowledge, and four organisation members of a consortium were central to the network. Social network analysis allowed us to create a graphic representation of the network. Social network analysis is a useful methodology to objectively characterise integrated networks.

IMAT (Integrated Multidisciplinary Analysis Tool) user's guide for the VAX/VMS computer

NASA Technical Reports Server (NTRS)

Meissner, Frances T. (Editor)

1988-01-01

The Integrated Multidisciplinary Analysis Tool (IMAT) is a computer software system for the VAX/VMS computer developed at the Langley Research Center. IMAT provides researchers and analysts with an efficient capability to analyze satellite control systems influenced by structural dynamics. Using a menu-driven executive system, IMAT leads the user through the program options. IMAT links a relational database manager to commercial and in-house structural and controls analysis codes. This paper describes the IMAT software system and how to use it.

Evaluation of Contamination Inspection and Analysis Methods through Modeling System Performance

NASA Technical Reports Server (NTRS)

Seasly, Elaine; Dever, Jason; Stuban, Steven M. F.

2016-01-01

Contamination is usually identified as a risk on the risk register for sensitive space systems hardware. Despite detailed, time-consuming, and costly contamination control efforts during assembly, integration, and test of space systems, contaminants are still found during visual inspections of hardware. Improved methods are needed to gather information during systems integration to catch potential contamination issues earlier and manage contamination risks better. This research explores evaluation of contamination inspection and analysis methods to determine optical system sensitivity to minimum detectable molecular contamination levels based on IEST-STD-CC1246E non-volatile residue (NVR) cleanliness levels. Potential future degradation of the system is modeled given chosen modules representative of optical elements in an optical system, minimum detectable molecular contamination levels for a chosen inspection and analysis method, and determining the effect of contamination on the system. By modeling system performance based on when molecular contamination is detected during systems integration and at what cleanliness level, the decision maker can perform trades amongst different inspection and analysis methods and determine if a planned method is adequate to meet system requirements and manage contamination risk.

IMG: the integrated microbial genomes database and comparative analysis system

PubMed Central

Markowitz, Victor M.; Chen, I-Min A.; Palaniappan, Krishna; Chu, Ken; Szeto, Ernest; Grechkin, Yuri; Ratner, Anna; Jacob, Biju; Huang, Jinghua; Williams, Peter; Huntemann, Marcel; Anderson, Iain; Mavromatis, Konstantinos; Ivanova, Natalia N.; Kyrpides, Nikos C.

2012-01-01

The Integrated Microbial Genomes (IMG) system serves as a community resource for comparative analysis of publicly available genomes in a comprehensive integrated context. IMG integrates publicly available draft and complete genomes from all three domains of life with a large number of plasmids and viruses. IMG provides tools and viewers for analyzing and reviewing the annotations of genes and genomes in a comparative context. IMG's data content and analytical capabilities have been continuously extended through regular updates since its first release in March 2005. IMG is available at http://img.jgi.doe.gov. Companion IMG systems provide support for expert review of genome annotations (IMG/ER: http://img.jgi.doe.gov/er), teaching courses and training in microbial genome analysis (IMG/EDU: http://img.jgi.doe.gov/edu) and analysis of genomes related to the Human Microbiome Project (IMG/HMP: http://www.hmpdacc-resources.org/img_hmp). PMID:22194640

IMG: the Integrated Microbial Genomes database and comparative analysis system.

PubMed

Markowitz, Victor M; Chen, I-Min A; Palaniappan, Krishna; Chu, Ken; Szeto, Ernest; Grechkin, Yuri; Ratner, Anna; Jacob, Biju; Huang, Jinghua; Williams, Peter; Huntemann, Marcel; Anderson, Iain; Mavromatis, Konstantinos; Ivanova, Natalia N; Kyrpides, Nikos C

2012-01-01

The Integrated Microbial Genomes (IMG) system serves as a community resource for comparative analysis of publicly available genomes in a comprehensive integrated context. IMG integrates publicly available draft and complete genomes from all three domains of life with a large number of plasmids and viruses. IMG provides tools and viewers for analyzing and reviewing the annotations of genes and genomes in a comparative context. IMG's data content and analytical capabilities have been continuously extended through regular updates since its first release in March 2005. IMG is available at http://img.jgi.doe.gov. Companion IMG systems provide support for expert review of genome annotations (IMG/ER: http://img.jgi.doe.gov/er), teaching courses and training in microbial genome analysis (IMG/EDU: http://img.jgi.doe.gov/edu) and analysis of genomes related to the Human Microbiome Project (IMG/HMP: http://www.hmpdacc-resources.org/img_hmp).

System integration report

NASA Technical Reports Server (NTRS)

Badler, N. I.; Korein, J. D.; Meyer, C.; Manoochehri, K.; Rovins, J.; Beale, J.; Barr, B.

1985-01-01

Several areas that arise from the system integration issue were examined. Intersystem analysis is discussed as it relates to software development, shared data bases and interfaces between TEMPUS and PLAID, shaded graphics rendering systems, object design (BUILD), the TEMPUS animation system, anthropometric lab integration, ongoing TEMPUS support and maintenance, and the impact of UNIX and local workstations on the OSDS environment.

Viewpoint on ISA TR84.0.02--simplified methods and fault tree analysis.

PubMed

Summers, A E

2000-01-01

ANSI/ISA-S84.01-1996 and IEC 61508 require the establishment of a safety integrity level for any safety instrumented system or safety related system used to mitigate risk. Each stage of design, operation, maintenance, and testing is judged against this safety integrity level. Quantitative techniques can be used to verify whether the safety integrity level is met. ISA-dTR84.0.02 is a technical report under development by ISA, which discusses how to apply quantitative analysis techniques to safety instrumented systems. This paper discusses two of those techniques: (1) Simplified equations and (2) Fault tree analysis.

TOPICAL REVIEW: Integrated genetic analysis microsystems

NASA Astrophysics Data System (ADS)

Lagally, Eric T.; Mathies, Richard A.

2004-12-01

With the completion of the Human Genome Project and the ongoing DNA sequencing of the genomes of other animals, bacteria, plants and others, a wealth of new information about the genetic composition of organisms has become available. However, as the demand for sequence information grows, so does the workload required both to generate this sequence and to use it for targeted genetic analysis. Microfabricated genetic analysis systems are well poised to assist in the collection and use of these data through increased analysis speed, lower analysis cost and higher parallelism leading to increased assay throughput. In addition, such integrated microsystems may point the way to targeted genetic experiments on single cells and in other areas that are otherwise very difficult. Concomitant with these advantages, such systems, when fully integrated, should be capable of forming portable systems for high-speed in situ analyses, enabling a new standard in disciplines such as clinical chemistry, forensics, biowarfare detection and epidemiology. This review will discuss the various technologies available for genetic analysis on the microscale, and efforts to integrate them to form fully functional robust analysis devices.

Unified Approach to Modeling and Simulation of Space Communication Networks and Systems

NASA Technical Reports Server (NTRS)

Barritt, Brian; Bhasin, Kul; Eddy, Wesley; Matthews, Seth

2010-01-01

Network simulator software tools are often used to model the behaviors and interactions of applications, protocols, packets, and data links in terrestrial communication networks. Other software tools that model the physics, orbital dynamics, and RF characteristics of space systems have matured to allow for rapid, detailed analysis of space communication links. However, the absence of a unified toolset that integrates the two modeling approaches has encumbered the systems engineers tasked with the design, architecture, and analysis of complex space communication networks and systems. This paper presents the unified approach and describes the motivation, challenges, and our solution - the customization of the network simulator to integrate with astronautical analysis software tools for high-fidelity end-to-end simulation. Keywords space; communication; systems; networking; simulation; modeling; QualNet; STK; integration; space networks

Integrated network analysis and effective tools in plant systems biology

PubMed Central

Fukushima, Atsushi; Kanaya, Shigehiko; Nishida, Kozo

2014-01-01

One of the ultimate goals in plant systems biology is to elucidate the genotype-phenotype relationship in plant cellular systems. Integrated network analysis that combines omics data with mathematical models has received particular attention. Here we focus on the latest cutting-edge computational advances that facilitate their combination. We highlight (1) network visualization tools, (2) pathway analyses, (3) genome-scale metabolic reconstruction, and (4) the integration of high-throughput experimental data and mathematical models. Multi-omics data that contain the genome, transcriptome, proteome, and metabolome and mathematical models are expected to integrate and expand our knowledge of complex plant metabolisms. PMID:25408696

A Study on Aircraft Engine Control Systems for Integrated Flight and Propulsion Control

NASA Astrophysics Data System (ADS)

Yamane, Hideaki; Matsunaga, Yasushi; Kusakawa, Takeshi

A flyable FADEC system engineering model incorporating Integrated Flight and Propulsion Control (IFPC) concept is developed for a highly maneuverable aircraft and a fighter-class engine. An overview of the FADEC system and functional assignments for its components such as the Engine Control Unit (ECU) and the Integrated Control Unit (ICU) are described. Overall system reliability analysis, convex analysis and multivariable controller design for the engine, fault detection/redundancy management, and response characteristics of a fuel system are addressed. The engine control performance of the FADEC is demonstrated by hardware-in-the-loop simulation for fast acceleration and thrust transient characteristics.

Full Life Cycle of Data Analysis with Climate Model Diagnostic Analyzer (CMDA)

NASA Astrophysics Data System (ADS)

Lee, S.; Zhai, C.; Pan, L.; Tang, B.; Zhang, J.; Bao, Q.; Malarout, N.

2017-12-01

We have developed a system that supports the full life cycle of a data analysis process, from data discovery, to data customization, to analysis, to reanalysis, to publication, and to reproduction. The system called Climate Model Diagnostic Analyzer (CMDA) is designed to demonstrate that the full life cycle of data analysis can be supported within one integrated system for climate model diagnostic evaluation with global observational and reanalysis datasets. CMDA has four subsystems that are highly integrated to support the analysis life cycle. Data System manages datasets used by CMDA analysis tools, Analysis System manages CMDA analysis tools which are all web services, Provenance System manages the meta data of CMDA datasets and the provenance of CMDA analysis history, and Recommendation System extracts knowledge from CMDA usage history and recommends datasets/analysis tools to users. These four subsystems are not only highly integrated but also easily expandable. New datasets can be easily added to Data System and scanned to be visible to the other subsystems. New analysis tools can be easily registered to be available in the Analysis System and Provenance System. With CMDA, a user can start a data analysis process by discovering datasets of relevance to their research topic using the Recommendation System. Next, the user can customize the discovered datasets for their scientific use (e.g. anomaly calculation, regridding, etc) with tools in the Analysis System. Next, the user can do their analysis with the tools (e.g. conditional sampling, time averaging, spatial averaging) in the Analysis System. Next, the user can reanalyze the datasets based on the previously stored analysis provenance in the Provenance System. Further, they can publish their analysis process and result to the Provenance System to share with other users. Finally, any user can reproduce the published analysis process and results. By supporting the full life cycle of climate data analysis, CMDA improves the research productivity and collaboration level of its user.

An integrative approach to space-flight physiology using systems analysis and mathematical simulation

NASA Technical Reports Server (NTRS)

Leonard, J. I.; White, R. J.; Rummel, J. A.

1980-01-01

An approach was developed to aid in the integration of many of the biomedical findings of space flight, using systems analysis. The mathematical tools used in accomplishing this task include an automated data base, a biostatistical and data analysis system, and a wide variety of mathematical simulation models of physiological systems. A keystone of this effort was the evaluation of physiological hypotheses using the simulation models and the prediction of the consequences of these hypotheses on many physiological quantities, some of which were not amenable to direct measurement. This approach led to improvements in the model, refinements of the hypotheses, a tentative integrated hypothesis for adaptation to weightlessness, and specific recommendations for new flight experiments.

Energy efficient engine component development and integration program

NASA Technical Reports Server (NTRS)

1981-01-01

Accomplishments in the Energy Efficient Engine Component Development and Integration program during the period of April 1, 1981 through September 30, 1981 are discussed. The major topics considered are: (1) propulsion system analysis, design, and integration; (2) engine component analysis, design, and development; (3) core engine tests; and (4) integrated core/low spool testing.

Analysis and evaluation of functional status of lower extremity amputee-appliance systems: an integrated approach.

PubMed

Ganguli, S

1976-11-01

This paper introduces an integrated, objective and biomechanically sound approach for the analysis and evaluation of the functional status of lower extremity amputee-appliance systems. The method is demonstrated here in its application to the unilateral lower extremity amputee-axillary crutches system and the unilateral below-knee amputee-PTB prosthesis system, both of which are commonly encountered in day-to-day rehabilitation practice.

Integrated remote sensing and visualization (IRSV) system for transportation infrastructure operations and management, phase one, volume 4 : use of knowledge integrated visual analytics system in supporting bridge management.

DOT National Transportation Integrated Search

2009-12-01

The goals of integration should be: Supporting domain oriented data analysis through the use of : knowledge augmented visual analytics system. In this project, we focus on: : Providing interactive data exploration for bridge managements. : ...

The Vehicle Integrated Performance Analysis Experience: Reconnecting With Technical Integration

NASA Technical Reports Server (NTRS)

McGhee, D. S.

2006-01-01

Very early in the Space Launch Initiative program, a small team of engineers at MSFC proposed a process for performing system-level assessments of a launch vehicle. Aimed primarily at providing insight and making NASA a smart buyer, the Vehicle Integrated Performance Analysis (VIPA) team was created. The difference between the VIPA effort and previous integration attempts is that VIPA a process using experienced people from various disciplines, which focuses them on a technically integrated assessment. The foundations of VIPA s process are described. The VIPA team also recognized the need to target early detailed analysis toward identifying significant systems issues. This process is driven by the T-model for technical integration. VIPA s approach to performing system-level technical integration is discussed in detail. The VIPA process significantly enhances the development and monitoring of realizable project requirements. VIPA s assessment validates the concept s stated performance, identifies significant issues either with the concept or the requirements, and then reintegrates these issues to determine impacts. This process is discussed along with a description of how it may be integrated into a program s insight and review process. The VIPA process has gained favor with both engineering and project organizations for being responsive and insightful

Integrated exhaust gas analysis system for aircraft turbine engine component testing

NASA Technical Reports Server (NTRS)

Summers, R. L.; Anderson, R. C.

1985-01-01

An integrated exhaust gas analysis system was designed and installed in the hot-section facility at the Lewis Research Center. The system is designed to operate either manually or automatically and also to be operated from a remote station. The system measures oxygen, water vapor, total hydrocarbons, carbon monoxide, carbon dioxide, and oxides of nitrogen. Two microprocessors control the system and the analyzers, collect data and process them into engineering units, and present the data to the facility computers and the system operator. Within the design of this system there are innovative concepts and procedures that are of general interest and application to other gas analysis tasks.

TSHIPS : Transportation shipping harmonization and integration planning system

DOT National Transportation Integrated Search

2001-03-01

This report documents the development of the Transportation Shipping Harmonization and Integration Planning System (TSHIPS). The TSHIPS project was developed to advance the state of the art in transportation systems analysis. Existing approaches and ...

Integrated modeling and analysis of the multiple electromechanical couplings for the direct driven feed system in machine tools

NASA Astrophysics Data System (ADS)

Yang, Xiaojun; Lu, Dun; Liu, Hui; Zhao, Wanhua

2018-06-01

The complicated electromechanical coupling phenomena due to different kinds of causes have significant influences on the dynamic precision of the direct driven feed system in machine tools. In this paper, a novel integrated modeling and analysis method of the multiple electromechanical couplings for the direct driven feed system in machine tools is presented. At first, four different kinds of electromechanical coupling phenomena in the direct driven feed system are analyzed systematically. Then a novel integrated modeling and analysis method of the electromechanical coupling which is influenced by multiple factors is put forward. In addition, the effects of multiple electromechanical couplings on the dynamic precision of the feed system and their main influencing factors are compared and discussed, respectively. Finally, the results of modeling and analysis are verified by the experiments. It finds out that multiple electromechanical coupling loops, which are overlapped and influenced by each other, are the main reasons of the displacement fluctuations in the direct driven feed system.

Executive Summary : Tower Cab System Integration Analysis

DOT National Transportation Integrated Search

1978-08-01

This report summarizes the principal results of the study of the integration into the tower cab of the systems being developed under the Major Systems Development Program (MSDP). The impact of these systems on the tower cab is analyzed from several p...

A regional scale modeling framework combining biogeochemical model with life cycle and economic analysis for integrated assessment of cropping systems.

PubMed

Tabatabaie, Seyed Mohammad Hossein; Bolte, John P; Murthy, Ganti S

2018-06-01

The goal of this study was to integrate a crop model, DNDC (DeNitrification-DeComposition), with life cycle assessment (LCA) and economic analysis models using a GIS-based integrated platform, ENVISION. The integrated model enables LCA practitioners to conduct integrated economic analysis and LCA on a regional scale while capturing the variability of soil emissions due to variation in regional factors during production of crops and biofuel feedstocks. In order to evaluate the integrated model, the corn-soybean cropping system in Eagle Creek Watershed, Indiana was studied and the integrated model was used to first model the soil emissions and then conduct the LCA as well as economic analysis. The results showed that the variation in soil emissions due to variation in weather is high causing some locations to be carbon sink in some years and source of CO 2 in other years. In order to test the model under different scenarios, two tillage scenarios were defined: 1) conventional tillage (CT) and 2) no tillage (NT) and analyzed with the model. The overall GHG emissions for the corn-soybean cropping system was simulated and results showed that the NT scenario resulted in lower soil GHG emissions compared to CT scenario. Moreover, global warming potential (GWP) of corn ethanol from well to pump varied between 57 and 92gCO 2 -eq./MJ while GWP under the NT system was lower than that of the CT system. The cost break-even point was calculated as $3612.5/ha in a two year corn-soybean cropping system and the results showed that under low and medium prices for corn and soybean most of the farms did not meet the break-even point. Copyright © 2017 Elsevier B.V. All rights reserved.

An expert system for integrated structural analysis and design optimization for aerospace structures

NASA Technical Reports Server (NTRS)

1992-01-01

The results of a research study on the development of an expert system for integrated structural analysis and design optimization is presented. An Object Representation Language (ORL) was developed first in conjunction with a rule-based system. This ORL/AI shell was then used to develop expert systems to provide assistance with a variety of structural analysis and design optimization tasks, in conjunction with procedural modules for finite element structural analysis and design optimization. The main goal of the research study was to provide expertise, judgment, and reasoning capabilities in the aerospace structural design process. This will allow engineers performing structural analysis and design, even without extensive experience in the field, to develop error-free, efficient and reliable structural designs very rapidly and cost-effectively. This would not only improve the productivity of design engineers and analysts, but also significantly reduce time to completion of structural design. An extensive literature survey in the field of structural analysis, design optimization, artificial intelligence, and database management systems and their application to the structural design process was first performed. A feasibility study was then performed, and the architecture and the conceptual design for the integrated 'intelligent' structural analysis and design optimization software was then developed. An Object Representation Language (ORL), in conjunction with a rule-based system, was then developed using C++. Such an approach would improve the expressiveness for knowledge representation (especially for structural analysis and design applications), provide ability to build very large and practical expert systems, and provide an efficient way for storing knowledge. Functional specifications for the expert systems were then developed. The ORL/AI shell was then used to develop a variety of modules of expert systems for a variety of modeling, finite element analysis, and design optimization tasks in the integrated aerospace structural design process. These expert systems were developed to work in conjunction with procedural finite element structural analysis and design optimization modules (developed in-house at SAT, Inc.). The complete software, AutoDesign, so developed, can be used for integrated 'intelligent' structural analysis and design optimization. The software was beta-tested at a variety of companies, used by a range of engineers with different levels of background and expertise. Based on the feedback obtained by such users, conclusions were developed and are provided.

An expert system for integrated structural analysis and design optimization for aerospace structures

NASA Astrophysics Data System (ADS)

1992-04-01

The results of a research study on the development of an expert system for integrated structural analysis and design optimization is presented. An Object Representation Language (ORL) was developed first in conjunction with a rule-based system. This ORL/AI shell was then used to develop expert systems to provide assistance with a variety of structural analysis and design optimization tasks, in conjunction with procedural modules for finite element structural analysis and design optimization. The main goal of the research study was to provide expertise, judgment, and reasoning capabilities in the aerospace structural design process. This will allow engineers performing structural analysis and design, even without extensive experience in the field, to develop error-free, efficient and reliable structural designs very rapidly and cost-effectively. This would not only improve the productivity of design engineers and analysts, but also significantly reduce time to completion of structural design. An extensive literature survey in the field of structural analysis, design optimization, artificial intelligence, and database management systems and their application to the structural design process was first performed. A feasibility study was then performed, and the architecture and the conceptual design for the integrated 'intelligent' structural analysis and design optimization software was then developed. An Object Representation Language (ORL), in conjunction with a rule-based system, was then developed using C++. Such an approach would improve the expressiveness for knowledge representation (especially for structural analysis and design applications), provide ability to build very large and practical expert systems, and provide an efficient way for storing knowledge. Functional specifications for the expert systems were then developed. The ORL/AI shell was then used to develop a variety of modules of expert systems for a variety of modeling, finite element analysis, and design optimization tasks in the integrated aerospace structural design process. These expert systems were developed to work in conjunction with procedural finite element structural analysis and design optimization modules (developed in-house at SAT, Inc.). The complete software, AutoDesign, so developed, can be used for integrated 'intelligent' structural analysis and design optimization. The software was beta-tested at a variety of companies, used by a range of engineers with different levels of background and expertise. Based on the feedback obtained by such users, conclusions were developed and are provided.

Optical integrator for optical dark-soliton detection and pulse shaping.

PubMed

Ngo, Nam Quoc

2006-09-10

The design and analysis of an Nth-order optical integrator using the digital filter technique is presented. The optical integrator is synthesized using planar-waveguide technology. It is shown that a first-order optical integrator can be used as an optical dark-soliton detector by converting an optical dark-soliton pulse into an optical bell-shaped pulse for ease of detection. The optical integrators can generate an optical step function, staircase function, and paraboliclike functions from input optical Gaussian pulses. The optical integrators may be potentially used as basic building blocks of all-optical signal processing systems because the time integrals of signals may sometimes be required for further use or analysis. Furthermore, an optical integrator may be used for the shaping of optical pulses or in an optical feedback control system.

Early Design Choices: Capture, Model, Integrate, Analyze, Simulate

NASA Technical Reports Server (NTRS)

Malin, Jane T.

2004-01-01

I. Designs are constructed incrementally to meet requirements and solve problems: a) Requirements types: objectives, scenarios, constraints, ilities. etc. b) Problem/issue types: risk/safety, cost/difficulty, interaction, conflict, etc. II. Capture requirements, problems and solutions: a) Collect design and analysis products and make them accessible for integration and analysis; b) Link changes in design requirements, problems and solutions; and c) Harvest design data for design models and choice structures. III. System designs are constructed by multiple groups designing interacting subsystems a) Diverse problems, choice criteria, analysis methods and point solutions. IV. Support integration and global analysis of repercussions: a) System implications of point solutions; b) Broad analysis of interactions beyond totals of mass, cost, etc.

A Survey of CAD/CAM Technology Applications in the U.S. Shipbuilding Industry

DTIC Science & Technology

1984-01-01

operation for drafting. Computer Aided Engineering (CAE) analysis is used primarily to determine the validity of design characteristics and produc- tion...include time standard generation, sea trial analysis , and group Systems integration While no systems surveyed Aided Design (CAD) is the technology... analysis . is the largest problem involving software packages. are truly integrated, many are interfaced. Computer most interfaced category with links

Database integration for investigative data visualization with the Temporal Analysis System

NASA Astrophysics Data System (ADS)

Barth, Stephen W.

1997-02-01

This paper describes an effort to provide mechanisms for integration of existing law enforcement databases with the temporal analysis system (TAS) -- an application for analysis and visualization of military intelligence data. Such integration mechanisms are essential for bringing advanced military intelligence data handling software applications to bear on the analysis of data used in criminal investigations. Our approach involved applying a software application for intelligence message handling to the problem of data base conversion. This application provides mechanisms for distributed processing and delivery of converted data records to an end-user application. It also provides a flexible graphic user interface for development and customization in the field.

Modeling Tools for Propulsion Analysis and Computational Fluid Dynamics on the Internet

NASA Technical Reports Server (NTRS)

Muss, J. A.; Johnson, C. W.; Gotchy, M. B.

2000-01-01

The existing RocketWeb(TradeMark) Internet Analysis System (httr)://www.iohnsonrockets.com/rocketweb) provides an integrated set of advanced analysis tools that can be securely accessed over the Internet. Since these tools consist of both batch and interactive analysis codes, the system includes convenient methods for creating input files and evaluating the resulting data. The RocketWeb(TradeMark) system also contains many features that permit data sharing which, when further developed, will facilitate real-time, geographically diverse, collaborative engineering within a designated work group. Adding work group management functionality while simultaneously extending and integrating the system's set of design and analysis tools will create a system providing rigorous, controlled design development, reducing design cycle time and cost.

Performance analysis of Integrated Communication and Control System networks

NASA Technical Reports Server (NTRS)

Halevi, Y.; Ray, A.

1990-01-01

This paper presents statistical analysis of delays in Integrated Communication and Control System (ICCS) networks that are based on asynchronous time-division multiplexing. The models are obtained in closed form for analyzing control systems with randomly varying delays. The results of this research are applicable to ICCS design for complex dynamical processes like advanced aircraft and spacecraft, autonomous manufacturing plants, and chemical and processing plants.

The Post-Dam System. Volume 5. Harvard Project Manager (HPM).

DTIC Science & Technology

1992-10-01

cQllected and analyzed to determine structural integrity and usability. From this analysis, a repair schedule is developed. This is currently a time...information on mission-critical facility damage is collected and analyzed to determine structural integrity and usability. From this analysis, a repair...to determine repair strategies with an expert system, keep track of materials and equipment with a relational database management system, and

Systems integration of marketable subsystems: A collection of progress reports

NASA Technical Reports Server (NTRS)

1978-01-01

Monthly progress reports are given in the areas of marketable subsystems integration; development, design, and building of site data acquisition subsystems and data processing systems; operation of the solar test facility and a systems analysis.

Total systems design analysis of high performance structures

NASA Technical Reports Server (NTRS)

Verderaime, V.

1993-01-01

Designer-control parameters were identified at interdiscipline interfaces to optimize structural systems performance and downstream development and operations with reliability and least life-cycle cost. Interface tasks and iterations are tracked through a matrix of performance disciplines integration versus manufacturing, verification, and operations interactions for a total system design analysis. Performance integration tasks include shapes, sizes, environments, and materials. Integrity integrating tasks are reliability and recurring structural costs. Significant interface designer control parameters were noted as shapes, dimensions, probability range factors, and cost. Structural failure concept is presented, and first-order reliability and deterministic methods, benefits, and limitations are discussed. A deterministic reliability technique combining benefits of both is proposed for static structures which is also timely and economically verifiable. Though launch vehicle environments were primarily considered, the system design process is applicable to any surface system using its own unique filed environments.

Advanced Satellite Workstation - An integrated workstation environment for operational support of satellite system planning and analysis

NASA Astrophysics Data System (ADS)

Hamilton, Marvin J.; Sutton, Stewart A.

A prototype integrated environment, the Advanced Satellite Workstation (ASW), which was developed and delivered for evaluation and operator feedback in an operational satellite control center, is described. The current ASW hardware consists of a Sun Workstation and Macintosh II Workstation connected via an ethernet Network Hardware and Software, Laser Disk System, Optical Storage System, and Telemetry Data File Interface. The central objective of ASW is to provide an intelligent decision support and training environment for operator/analysis of complex systems such as satellites. Compared to the many recent workstation implementations that incorporate graphical telemetry displays and expert systems, ASW provides a considerably broader look at intelligent, integrated environments for decision support, based on the premise that the central features of such an environment are intelligent data access and integrated toolsets.

Development of Spreadsheet-Based Integrated Transaction Processing Systems and Financial Reporting Systems

NASA Astrophysics Data System (ADS)

Ariana, I. M.; Bagiada, I. M.

2018-01-01

Development of spreadsheet-based integrated transaction processing systems and financial reporting systems is intended to optimize the capabilities of spreadsheet in accounting data processing. The purpose of this study are: 1) to describe the spreadsheet-based integrated transaction processing systems and financial reporting systems; 2) to test its technical and operational feasibility. This study type is research and development. The main steps of study are: 1) needs analysis (need assessment); 2) developing spreadsheet-based integrated transaction processing systems and financial reporting systems; and 3) testing the feasibility of spreadsheet-based integrated transaction processing systems and financial reporting systems. The technical feasibility include the ability of hardware and operating systems to respond the application of accounting, simplicity and ease of use. Operational feasibility include the ability of users using accounting applications, the ability of accounting applications to produce information, and control applications of the accounting applications. The instrument used to assess the technical and operational feasibility of the systems is the expert perception questionnaire. The instrument uses 4 Likert scale, from 1 (strongly disagree) to 4 (strongly agree). Data were analyzed using percentage analysis by comparing the number of answers within one (1) item by the number of ideal answer within one (1) item. Spreadsheet-based integrated transaction processing systems and financial reporting systems integrate sales, purchases, and cash transaction processing systems to produce financial reports (statement of profit or loss and other comprehensive income, statement of changes in equity, statement of financial position, and statement of cash flows) and other reports. Spreadsheet-based integrated transaction processing systems and financial reporting systems is feasible from the technical aspects (87.50%) and operational aspects (84.17%).

System integration of marketable subsystems. [for residential solar heating and cooling

NASA Technical Reports Server (NTRS)

1979-01-01

Progress is reported in the following areas: systems integration of marketable subsystems; development, design, and building of site data acquisition subsystems; development and operation of the central data processing system; operation of the MSFC Solar Test Facility; and systems analysis.

Microcomputer design and analysis of the cable catenary large space antenna system

NASA Technical Reports Server (NTRS)

Akle, W.

1984-01-01

The use of microcomputers in the design of a cable catenary large space antenna system is discussed. The development of a system design capability, data base utilization, systems integration, program structure and logic, and integrated graphics output are discussed.

Practical Application of Model-based Programming and State-based Architecture to Space Missions

NASA Technical Reports Server (NTRS)

Horvath, Gregory; Ingham, Michel; Chung, Seung; Martin, Oliver; Williams, Brian

2006-01-01

A viewgraph presentation to develop models from systems engineers that accomplish mission objectives and manage the health of the system is shown. The topics include: 1) Overview; 2) Motivation; 3) Objective/Vision; 4) Approach; 5) Background: The Mission Data System; 6) Background: State-based Control Architecture System; 7) Background: State Analysis; 8) Overview of State Analysis; 9) Background: MDS Software Frameworks; 10) Background: Model-based Programming; 10) Background: Titan Model-based Executive; 11) Model-based Execution Architecture; 12) Compatibility Analysis of MDS and Titan Architectures; 13) Integrating Model-based Programming and Execution into the Architecture; 14) State Analysis and Modeling; 15) IMU Subsystem State Effects Diagram; 16) Titan Subsystem Model: IMU Health; 17) Integrating Model-based Programming and Execution into the Software IMU; 18) Testing Program; 19) Computationally Tractable State Estimation & Fault Diagnosis; 20) Diagnostic Algorithm Performance; 21) Integration and Test Issues; 22) Demonstrated Benefits; and 23) Next Steps

Information Extraction for System-Software Safety Analysis: Calendar Year 2007 Year-End Report

NASA Technical Reports Server (NTRS)

Malin, Jane T.

2008-01-01

This annual report describes work to integrate a set of tools to support early model-based analysis of failures and hazards due to system-software interactions. The tools perform and assist analysts in the following tasks: 1) extract model parts from text for architecture and safety/hazard models; 2) combine the parts with library information to develop the models for visualization and analysis; 3) perform graph analysis on the models to identify possible paths from hazard sources to vulnerable entities and functions, in nominal and anomalous system-software configurations; 4) perform discrete-time-based simulation on the models to investigate scenarios where these paths may play a role in failures and mishaps; and 5) identify resulting candidate scenarios for software integration testing. This paper describes new challenges in a NASA abort system case, and enhancements made to develop the integrated tool set.

Exploration of the integration of care for persons with a traumatic brain injury using social network analysis methodology

PubMed Central

Lamontagne, Marie-Eve

2013-01-01

Introduction Integration is a popular strategy to increase the quality of care within systems of care. However, there is no common language, approach or tool allowing for a valid description, comparison and evaluation of integrated care. Social network analysis could be a viable methodology to provide an objective picture of integrated networks. Goal of the article To illustrate social network analysis use in the context of systems of care for traumatic brain injury. Method We surveyed members of a network using a validated questionnaire to determine the links between them. We determined the density, centrality, multiplexity, and quality of the links reported. Results The network was described as moderately dense (0.6), the most prevalent link was knowledge, and four organisation members of a consortium were central to the network. Social network analysis allowed us to create a graphic representation of the network. Conclusion Social network analysis is a useful methodology to objectively characterise integrated networks. PMID:24250281

Using integrated models to minimize environmentally induced wavefront error in optomechanical design and analysis

NASA Astrophysics Data System (ADS)

Genberg, Victor L.; Michels, Gregory J.

2017-08-01

The ultimate design goal of an optical system subjected to dynamic loads is to minimize system level wavefront error (WFE). In random response analysis, system WFE is difficult to predict from finite element results due to the loss of phase information. In the past, the use of ystem WFE was limited by the difficulty of obtaining a linear optics model. In this paper, an automated method for determining system level WFE using a linear optics model is presented. An error estimate is included in the analysis output based on fitting errors of mode shapes. The technique is demonstrated by example with SigFit, a commercially available tool integrating mechanical analysis with optical analysis.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shahidehpour, Mohammad

Integrating 20% or more wind energy into the system and transmitting large sums of wind energy over long distances will require a decision making capability that can handle very large scale power systems with tens of thousands of buses and lines. There is a need to explore innovative analytical and implementation solutions for continuing reliable operations with the most economical integration of additional wind energy in power systems. A number of wind integration solution paths involve the adoption of new operating policies, dynamic scheduling of wind power across interties, pooling integration services, and adopting new transmission scheduling practices. Such practicesmore » can be examined by the decision tool developed by this project. This project developed a very efficient decision tool called Wind INtegration Simulator (WINS) and applied WINS to facilitate wind energy integration studies. WINS focused on augmenting the existing power utility capabilities to support collaborative planning, analysis, and wind integration project implementations. WINS also had the capability of simulating energy storage facilities so that feasibility studies of integrated wind energy system applications can be performed for systems with high wind energy penetrations. The development of WINS represents a major expansion of a very efficient decision tool called POwer Market Simulator (POMS), which was developed by IIT and has been used extensively for power system studies for decades. Specifically, WINS provides the following superiorities; (1) An integrated framework is included in WINS for the comprehensive modeling of DC transmission configurations, including mono-pole, bi-pole, tri-pole, back-to-back, and multi-terminal connection, as well as AC/DC converter models including current source converters (CSC) and voltage source converters (VSC); (2) An existing shortcoming of traditional decision tools for wind integration is the limited availability of user interface, i.e., decision results are often text-based demonstrations. WINS includes a powerful visualization tool and user interface capability for transmission analyses, planning, and assessment, which will be of great interest to power market participants, power system planners and operators, and state and federal regulatory entities; and (3) WINS can handle extended transmission models for wind integration studies. WINS models include limitations on transmission flow as well as bus voltage for analyzing power system states. The existing decision tools often consider transmission flow constraints (dc power flow) alone which could result in the over-utilization of existing resources when analyzing wind integration. WINS can be used to assist power market participants including transmission companies, independent system operators, power system operators in vertically integrated utilities, wind energy developers, and regulatory agencies to analyze economics, security, and reliability of various options for wind integration including transmission upgrades and the planning of new transmission facilities. WINS can also be used by industry for the offline training of reliability and operation personnel when analyzing wind integration uncertainties, identifying critical spots in power system operation, analyzing power system vulnerabilities, and providing credible decisions for examining operation and planning options for wind integration. Researches in this project on wind integration included (1) Development of WINS; (2) Transmission Congestion Analysis in the Eastern Interconnection; (3) Analysis of 2030 Large-Scale Wind Energy Integration in the Eastern Interconnection; (4) Large-scale Analysis of 2018 Wind Energy Integration in the Eastern U.S. Interconnection. The research resulted in 33 papers, 9 presentations, 9 PhD degrees, 4 MS degrees, and 7 awards. The education activities in this project on wind energy included (1) Wind Energy Training Facility Development; (2) Wind Energy Course Development.« less

ATLAS, an integrated structural analysis and design system. Volume 4: Random access file catalog

NASA Technical Reports Server (NTRS)

Gray, F. P., Jr. (Editor)

1979-01-01

A complete catalog is presented for the random access files used by the ATLAS integrated structural analysis and design system. ATLAS consists of several technical computation modules which output data matrices to corresponding random access file. A description of the matrices written on these files is contained herein.

Study on Network Error Analysis and Locating based on Integrated Information Decision System

NASA Astrophysics Data System (ADS)

Yang, F.; Dong, Z. H.

2017-10-01

Integrated information decision system (IIDS) integrates multiple sub-system developed by many facilities, including almost hundred kinds of software, which provides with various services, such as email, short messages, drawing and sharing. Because the under-layer protocols are different, user standards are not unified, many errors are occurred during the stages of setup, configuration, and operation, which seriously affect the usage. Because the errors are various, which may be happened in different operation phases, stages, TCP/IP communication protocol layers, sub-system software, it is necessary to design a network error analysis and locating tool for IIDS to solve the above problems. This paper studies on network error analysis and locating based on IIDS, which provides strong theory and technology supports for the running and communicating of IIDS.

From proteomics to systems biology: MAPA, MASS WESTERN, PROMEX, and COVAIN as a user-oriented platform.

PubMed

Weckwerth, Wolfram; Wienkoop, Stefanie; Hoehenwarter, Wolfgang; Egelhofer, Volker; Sun, Xiaoliang

2014-01-01

Genome sequencing and systems biology are revolutionizing life sciences. Proteomics emerged as a fundamental technique of this novel research area as it is the basis for gene function analysis and modeling of dynamic protein networks. Here a complete proteomics platform suited for functional genomics and systems biology is presented. The strategy includes MAPA (mass accuracy precursor alignment; http://www.univie.ac.at/mosys/software.html ) as a rapid exploratory analysis step; MASS WESTERN for targeted proteomics; COVAIN ( http://www.univie.ac.at/mosys/software.html ) for multivariate statistical analysis, data integration, and data mining; and PROMEX ( http://www.univie.ac.at/mosys/databases.html ) as a database module for proteogenomics and proteotypic peptides for targeted analysis. Moreover, the presented platform can also be utilized to integrate metabolomics and transcriptomics data for the analysis of metabolite-protein-transcript correlations and time course analysis using COVAIN. Examples for the integration of MAPA and MASS WESTERN data, proteogenomic and metabolic modeling approaches for functional genomics, phosphoproteomics by integration of MOAC (metal-oxide affinity chromatography) with MAPA, and the integration of metabolomics, transcriptomics, proteomics, and physiological data using this platform are presented. All software and step-by-step tutorials for data processing and data mining can be downloaded from http://www.univie.ac.at/mosys/software.html.

Integration of Design, Thermal, Structural, and Optical Analysis, Including Thermal Animation

NASA Technical Reports Server (NTRS)

Amundsen, Ruth M.

1993-01-01

In many industries there has recently been a concerted movement toward 'quality management' and the issue of how to accomplish work more efficiently. Part of this effort is focused on concurrent engineering; the idea of integrating the design and analysis processes so that they are not separate, sequential processes (often involving design rework due to analytical findings) but instead form an integrated system with smooth transfers of information. Presented herein are several specific examples of concurrent engineering methods being carried out at Langley Research Center (LaRC): integration of thermal, structural and optical analyses to predict changes in optical performance based on thermal and structural effects; integration of the CAD design process with thermal and structural analyses; and integration of analysis and presentation by animating the thermal response of a system as an active color map -- a highly effective visual indication of heat flow.

An integrated modeling and design tool for advanced optical spacecraft

NASA Technical Reports Server (NTRS)

Briggs, Hugh C.

1992-01-01

Consideration is given to the design and status of the Integrated Modeling of Optical Systems (IMOS) tool and to critical design issues. A multidisciplinary spacecraft design and analysis tool with support for structural dynamics, controls, thermal analysis, and optics, IMOS provides rapid and accurate end-to-end performance analysis, simulations, and optimization of advanced space-based optical systems. The requirements for IMOS-supported numerical arrays, user defined data structures, and a hierarchical data base are outlined, and initial experience with the tool is summarized. A simulation of a flexible telescope illustrates the integrated nature of the tools.

General Pressurization Model in Simscape

NASA Technical Reports Server (NTRS)

Servin, Mario; Garcia, Vicky

2010-01-01

System integration is an essential part of the engineering design process. The Ares I Upper Stage (US) is a complex system which is made up of thousands of components assembled into subsystems including a J2-X engine, liquid hydrogen (LH2) and liquid oxygen (LO2) tanks, avionics, thrust vector control, motors, etc. System integration is the task of connecting together all of the subsystems into one large system. To ensure that all the components will "fit together" as well as safety and, quality, integration analysis is required. Integration analysis verifies that, as an integrated system, the system will behave as designed. Models that represent the actual subsystems are built for more comprehensive analysis. Matlab has been an instrument widely use by engineers to construct mathematical models of systems. Simulink, one of the tools offered by Matlab, provides multi-domain graphical environment to simulate and design time-varying systems. Simulink is a powerful tool to analyze the dynamic behavior of systems over time. Furthermore, Simscape, a tool provided by Simulink, allows users to model physical (such as mechanical, thermal and hydraulic) systems using physical networks. Using Simscape, a model representing an inflow of gas to a pressurized tank was created where the temperature and pressure of the tank are measured over time to show the behavior of the gas. By further incorporation of Simscape into model building, the full potential of this software can be discovered and it hopefully can become a more utilized tool.

Thermal-Acoustic Analysis of a Metallic Integrated Thermal Protection System Structure

NASA Technical Reports Server (NTRS)

Behnke, Marlana N.; Sharma, Anurag; Przekop, Adam; Rizzi, Stephen A.

2010-01-01

A study is undertaken to investigate the response of a representative integrated thermal protection system structure under combined thermal, aerodynamic pressure, and acoustic loadings. A two-step procedure is offered and consists of a heat transfer analysis followed by a nonlinear dynamic analysis under a combined loading environment. Both analyses are carried out in physical degrees-of-freedom using implicit and explicit solution techniques available in the Abaqus commercial finite-element code. The initial study is conducted on a reduced-size structure to keep the computational effort contained while validating the procedure and exploring the effects of individual loadings. An analysis of a full size integrated thermal protection system structure, which is of ultimate interest, is subsequently presented. The procedure is demonstrated to be a viable approach for analysis of spacecraft and hypersonic vehicle structures under a typical mission cycle with combined loadings characterized by largely different time-scales.

Integrated CZE-ESI-MS/MS system with an immobilized trypsin microreactor for online digestion and analysis of picogram amounts of RAW 264.7 cell lysate

PubMed Central

Sun, Liangliang; Zhu, Guijie; Dovichi, Norman J.

2013-01-01

A capillary zone electrophoresis (CZE) electrospray ionization (ESI) tandem mass spectrometry (MS/MS) system was integrated with an immobilized trypsin microreactor. The system was evaluated and then applied for online digestion and analysis of picogram loadings of RAW 264.7 cell lysate. Protein samples were dissolved in a buffer containing 50% (v/v) acetonitrile (ACN), and then directly loaded into the capillary for digestion, followed by CZE separation and MS/MS identification. The organic solvent (50% (v/v) ACN) assisted the immobilized trypsin digestion and simplified the protein sample preparation protocol. Neither protein reduction nor alkylation steps were employed, which minimized sample loss and contamination. The integrated CZE-ESI-MS/MS system generated confident identification of bovine serum albumin (BSA) with 19% sequence coverage and 14 peptide IDs when 20 fmole was loaded. When only 1 fmole BSA was injected, one BSA peptide was consistently detected. For the analysis of a standard protein mixture, the integrated system produced efficient protein digestion and confident identification for proteins with different molecular weights and isoelectric points when low fmole amount was loaded for each protein. We further applied the system for triplicate analysis of a RAW 264.7 cell lysate; 2 ± 1 and 7 ± 2 protein groups were confidently identified from only 300 pg and 3 ng loadings, respectively. The 300 pg sample loading corresponds to the protein content of three RAW 264.7 cells. In addition to high sensitivity analysis, the integrated CZE-ESI-MS/MS system produces good reproducibility in terms of peptide and protein IDs, peptide migration time, and peptide intensity. PMID:23510126

Coupled Cryogenic Thermal and Electrical Models for Transient Analysis of Superconducting Power Devices with Integrated Cryogenic Systems

NASA Astrophysics Data System (ADS)

Satyanarayana, S.; Indrakanti, S.; Kim, J.; Kim, C.; Pamidi, S.

2017-12-01

Benefits of an integrated high temperature superconducting (HTS) power system and the associated cryogenic systems on board an electric ship or aircraft are discussed. A versatile modelling methodology developed to assess the cryogenic thermal behavior of the integrated system with multiple HTS devices and the various potential configurations are introduced. The utility and effectiveness of the developed modelling methodology is demonstrated using a case study involving a hypothetical system including an HTS propulsion motor, an HTS generator and an HTS power cable cooled by an integrated cryogenic helium circulation system. Using the methodology, multiple configurations are studied. The required total cooling power and the ability to maintain each HTS device at the required operating temperatures are considered for each configuration and the trade-offs are discussed for each configuration. Transient analysis of temperature evolution in the cryogenic helium circulation loop in case of a system failure is carried out to arrive at the required critical response time. The analysis was also performed for a similar liquid nitrogen circulation for an isobaric condition and the cooling capacity ratio is used to compare the relative merits of the two cryogens.

The Environment for Application Software Integration and Execution (EASIE) version 1.0. Volume 1: Executive overview

NASA Technical Reports Server (NTRS)

Rowell, Lawrence F.; Davis, John S.

1989-01-01

The Environment for Application Software Integration and Execution (EASIE) provides a methodology and a set of software utility programs to ease the task of coordinating engineering design and analysis codes. EASIE was designed to meet the needs of conceptual design engineers that face the task of integrating many stand-alone engineering analysis programs. Using EASIE, programs are integrated through a relational database management system. Volume 1, Executive Overview, gives an overview of the functions provided by EASIE and describes their use. Three operational design systems based upon the EASIE software are briefly described.

An Integrated Solution for Performing Thermo-fluid Conjugate Analysis

NASA Technical Reports Server (NTRS)

Kornberg, Oren

2009-01-01

A method has been developed which integrates a fluid flow analyzer and a thermal analyzer to produce both steady state and transient results of 1-D, 2-D, and 3-D analysis models. The Generalized Fluid System Simulation Program (GFSSP) is a one dimensional, general purpose fluid analysis code which computes pressures and flow distributions in complex fluid networks. The MSC Systems Improved Numerical Differencing Analyzer (MSC.SINDA) is a one dimensional general purpose thermal analyzer that solves network representations of thermal systems. Both GFSSP and MSC.SINDA have graphical user interfaces which are used to build the respective model and prepare it for analysis. The SINDA/GFSSP Conjugate Integrator (SGCI) is a formbase graphical integration program used to set input parameters for the conjugate analyses and run the models. The contents of this paper describes SGCI and its thermo-fluids conjugate analysis techniques and capabilities by presenting results from some example models including the cryogenic chill down of a copper pipe, a bar between two walls in a fluid stream, and a solid plate creating a phase change in a flowing fluid.

Reliability studies of Integrated Modular Engine system designs

NASA Technical Reports Server (NTRS)

Hardy, Terry L.; Rapp, Douglas C.

1993-01-01

A study was performed to evaluate the reliability of Integrated Modular Engine (IME) concepts. Comparisons were made between networked IME systems and non-networked discrete systems using expander cycle configurations. Both redundant and non-redundant systems were analyzed. Binomial approximation and Markov analysis techniques were employed to evaluate total system reliability. In addition, Failure Modes and Effects Analyses (FMEA), Preliminary Hazard Analyses (PHA), and Fault Tree Analysis (FTA) were performed to allow detailed evaluation of the IME concept. A discussion of these system reliability concepts is also presented.

Reliability studies of integrated modular engine system designs

NASA Technical Reports Server (NTRS)

Hardy, Terry L.; Rapp, Douglas C.

1993-01-01

A study was performed to evaluate the reliability of Integrated Modular Engine (IME) concepts. Comparisons were made between networked IME systems and non-networked discrete systems using expander cycle configurations. Both redundant and non-redundant systems were analyzed. Binomial approximation and Markov analysis techniques were employed to evaluate total system reliability. In addition, Failure Modes and Effects Analyses (FMEA), Preliminary Hazard Analyses (PHA), and Fault Tree Analysis (FTA) were performed to allow detailed evaluation of the IME concept. A discussion of these system reliability concepts is also presented.

Reliability studies of integrated modular engine system designs

NASA Astrophysics Data System (ADS)

Hardy, Terry L.; Rapp, Douglas C.

1993-06-01

A study was performed to evaluate the reliability of Integrated Modular Engine (IME) concepts. Comparisons were made between networked IME systems and non-networked discrete systems using expander cycle configurations. Both redundant and non-redundant systems were analyzed. Binomial approximation and Markov analysis techniques were employed to evaluate total system reliability. In addition, Failure Modes and Effects Analyses (FMEA), Preliminary Hazard Analyses (PHA), and Fault Tree Analysis (FTA) were performed to allow detailed evaluation of the IME concept. A discussion of these system reliability concepts is also presented.

Reliability studies of Integrated Modular Engine system designs

NASA Astrophysics Data System (ADS)

Hardy, Terry L.; Rapp, Douglas C.

1993-06-01

A study was performed to evaluate the reliability of Integrated Modular Engine (IME) concepts. Comparisons were made between networked IME systems and non-networked discrete systems using expander cycle configurations. Both redundant and non-redundant systems were analyzed. Binomial approximation and Markov analysis techniques were employed to evaluate total system reliability. In addition, Failure Modes and Effects Analyses (FMEA), Preliminary Hazard Analyses (PHA), and Fault Tree Analysis (FTA) were performed to allow detailed evaluation of the IME concept. A discussion of these system reliability concepts is also presented.

A new analytical platform based on field-flow fractionation and olfactory sensor to improve the detection of viable and non-viable bacteria in food.

PubMed

Roda, Barbara; Mirasoli, Mara; Zattoni, Andrea; Casale, Monica; Oliveri, Paolo; Bigi, Alessandro; Reschiglian, Pierluigi; Simoni, Patrizia; Roda, Aldo

2016-10-01

An integrated sensing system is presented for the first time, where a metal oxide semiconductor sensor-based electronic olfactory system (MOS array), employed for pathogen bacteria identification based on their volatile organic compound (VOC) characterisation, is assisted by a preliminary separative technique based on gravitational field-flow fractionation (GrFFF). In the integrated system, a preliminary step using GrFFF fractionation of a complex sample provided bacteria-enriched fractions readily available for subsequent MOS array analysis. The MOS array signals were then analysed employing a chemometric approach using principal components analysis (PCA) for a first-data exploration, followed by linear discriminant analysis (LDA) as a classification tool, using the PCA scores as input variables. The ability of the GrFFF-MOS system to distinguish between viable and non-viable cells of the same strain was demonstrated for the first time, yielding 100 % ability of correct prediction. The integrated system was also applied as a proof of concept for multianalyte purposes, for the detection of two bacterial strains (Escherichia coli O157:H7 and Yersinia enterocolitica) simultaneously present in artificially contaminated milk samples, obtaining a 100 % ability of correct prediction. Acquired results show that GrFFF band slicing before MOS array analysis can significantly increase reliability and reproducibility of pathogen bacteria identification based on their VOC production, simplifying the analytical procedure and largely eliminating sample matrix effects. The developed GrFFF-MOS integrated system can be considered a simple straightforward approach for pathogen bacteria identification directly from their food matrix. Graphical abstract An integrated sensing system is presented for pathogen bacteria identification in food, in which field-flow fractionation is exploited to prepare enriched cell fractions prior to their analysis by electronic olfactory system analysis.

Fuel cell on-site integrated energy system parametric analysis of a residential complex

NASA Technical Reports Server (NTRS)

Simons, S. N.

1977-01-01

A parametric energy-use analysis was performed for a large apartment complex served by a fuel cell on-site integrated energy system (OS/IES). The variables parameterized include operating characteristics for four phosphoric acid fuel cells, eight OS/IES energy recovery systems, and four climatic locations. The annual fuel consumption for selected parametric combinations are presented and a breakeven economic analysis is presented for one parametric combination. The results show fuel cell electrical efficiency and system component choice have the greatest effect on annual fuel consumption; fuel cell thermal efficiency and geographic location have less of an effect.

Application of adaptive optics in complicated and integrated spatial multisensor system and its measurement analysis

NASA Astrophysics Data System (ADS)

Ding, Quanxin; Guo, Chunjie; Cai, Meng; Liu, Hua

2007-12-01

Adaptive Optics Expand System is a kind of new concept spatial equipment, which concerns system, cybernetics and informatics deeply, and is key way to improve advanced sensors ability. Traditional Zernike Phase Contrast Method is developed, and Accelerated High-level Phase Contrast Theory is established. Integration theory and mathematical simulation is achieved. Such Equipment, which is based on some crucial components, such as, core optical system, multi mode wavefront sensor and so on, is established for AOES advantageous configuration and global design. Studies on Complicated Spatial Multisensor System Integratation and measurement Analysis including error analysis are carried out.

Debris/Ice/TPS Assessment and Integrated Photographic Analysis of Shuttle Mission STS-80

NASA Technical Reports Server (NTRS)

Katnik, Gregory N.; Lin, Jill D.

1997-01-01

A debris/ice/thermal protection system (TPS) assessment and integrated photographic analysis was conducted for Shuttle mission STS-80. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the External Tank were assessed by the use of computer programs and infrared scanned data during cryogenic loading of the vehicle, followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or in-flight anomalies. This report documents the ice/debris/thermal protection system conditions and integrated photographic analysis of Shuttle mission Space Transportation System (STS-80) and the resulting effect on the Space Shuttle Program.

Environmental Control and Life Support Systems technology options for Space Station application

NASA Technical Reports Server (NTRS)

Hall, J. B., Jr.; Ferebee, M. J., Jr.; Sage, K. H.

1985-01-01

Continuous assessments regarding the suitability of candidate technologies for manned Space Stations will be needed over the next several years to obtain a basis for recommending the optimum system for an Initial Operating Capability (IOC) Space Station which is to be launched in the early 1990's. This paper has the objective to present analysis programs, the candidate recommendations, and the recommended approach for integration these candidates into the NASA Space Station reference configuration. Attention is given to ECLSS (Environmental Control and Life Support System) technology assessment program, an analysis approach for candidate technology recommendations, mission model variables, a candidate integration program, metabolic oxygen recovery, urine/flush water and all waste water recovery, wash water and condensate water recovery, and an integration analysis.

STINGRAY: system for integrated genomic resources and analysis.

PubMed

Wagner, Glauber; Jardim, Rodrigo; Tschoeke, Diogo A; Loureiro, Daniel R; Ocaña, Kary A C S; Ribeiro, Antonio C B; Emmel, Vanessa E; Probst, Christian M; Pitaluga, André N; Grisard, Edmundo C; Cavalcanti, Maria C; Campos, Maria L M; Mattoso, Marta; Dávila, Alberto M R

2014-03-07

The STINGRAY system has been conceived to ease the tasks of integrating, analyzing, annotating and presenting genomic and expression data from Sanger and Next Generation Sequencing (NGS) platforms. STINGRAY includes: (a) a complete and integrated workflow (more than 20 bioinformatics tools) ranging from functional annotation to phylogeny; (b) a MySQL database schema, suitable for data integration and user access control; and (c) a user-friendly graphical web-based interface that makes the system intuitive, facilitating the tasks of data analysis and annotation. STINGRAY showed to be an easy to use and complete system for analyzing sequencing data. While both Sanger and NGS platforms are supported, the system could be faster using Sanger data, since the large NGS datasets could potentially slow down the MySQL database usage. STINGRAY is available at http://stingray.biowebdb.org and the open source code at http://sourceforge.net/projects/stingray-biowebdb/.

Integrating a geographic information system, a scientific visualization system and an orographic precipitation model

USGS Publications Warehouse

Hay, L.; Knapp, L.

1996-01-01

Investigating natural, potential, and man-induced impacts on hydrological systems commonly requires complex modelling with overlapping data requirements, and massive amounts of one- to four-dimensional data at multiple scales and formats. Given the complexity of most hydrological studies, the requisite software infrastructure must incorporate many components including simulation modelling, spatial analysis and flexible, intuitive displays. There is a general requirement for a set of capabilities to support scientific analysis which, at this time, can only come from an integration of several software components. Integration of geographic information systems (GISs) and scientific visualization systems (SVSs) is a powerful technique for developing and analysing complex models. This paper describes the integration of an orographic precipitation model, a GIS and a SVS. The combination of these individual components provides a robust infrastructure which allows the scientist to work with the full dimensionality of the data and to examine the data in a more intuitive manner.

STINGRAY: system for integrated genomic resources and analysis

PubMed Central

2014-01-01

Background The STINGRAY system has been conceived to ease the tasks of integrating, analyzing, annotating and presenting genomic and expression data from Sanger and Next Generation Sequencing (NGS) platforms. Findings STINGRAY includes: (a) a complete and integrated workflow (more than 20 bioinformatics tools) ranging from functional annotation to phylogeny; (b) a MySQL database schema, suitable for data integration and user access control; and (c) a user-friendly graphical web-based interface that makes the system intuitive, facilitating the tasks of data analysis and annotation. Conclusion STINGRAY showed to be an easy to use and complete system for analyzing sequencing data. While both Sanger and NGS platforms are supported, the system could be faster using Sanger data, since the large NGS datasets could potentially slow down the MySQL database usage. STINGRAY is available at http://stingray.biowebdb.org and the open source code at http://sourceforge.net/projects/stingray-biowebdb/. PMID:24606808

Comparative genome analysis in the integrated microbial genomes (IMG) system.

PubMed

Markowitz, Victor M; Kyrpides, Nikos C

2007-01-01

Comparative genome analysis is critical for the effective exploration of a rapidly growing number of complete and draft sequences for microbial genomes. The Integrated Microbial Genomes (IMG) system (img.jgi.doe.gov) has been developed as a community resource that provides support for comparative analysis of microbial genomes in an integrated context. IMG allows users to navigate the multidimensional microbial genome data space and focus their analysis on a subset of genes, genomes, and functions of interest. IMG provides graphical viewers, summaries, and occurrence profile tools for comparing genes, pathways, and functions (terms) across specific genomes. Genes can be further examined using gene neighborhoods and compared with sequence alignment tools.

Multi-viewer tracking integral imaging system and its viewing zone analysis.

PubMed

Park, Gilbae; Jung, Jae-Hyun; Hong, Keehoon; Kim, Yunhee; Kim, Young-Hoon; Min, Sung-Wook; Lee, Byoungho

2009-09-28

We propose a multi-viewer tracking integral imaging system for viewing angle and viewing zone improvement. In the tracking integral imaging system, the pickup angles in each elemental lens in the lens array are decided by the positions of viewers, which means the elemental image can be made for each viewer to provide wider viewing angle and larger viewing zone. Our tracking integral imaging system is implemented with an infrared camera and infrared light emitting diodes which can track the viewers' exact positions robustly. For multiple viewers to watch integrated three-dimensional images in the tracking integral imaging system, it is needed to formulate the relationship between the multiple viewers' positions and the elemental images. We analyzed the relationship and the conditions for the multiple viewers, and verified them by the implementation of two-viewer tracking integral imaging system.

Systems and methods for integrating ion mobility and ion trap mass spectrometers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ibrahim, Yehia M.; Garimella, Sandilya; Prost, Spencer A.

Described herein are examples of systems and methods for integrating IMS and MS systems. In certain examples, systems and methods for decoding double multiplexed data are described. The systems and methods can also perform multiple refining procedures in order to minimize the demultiplexing artifacts. The systems and methods can be used, for example, for the analysis of proteomic and petroleum samples, where the integration of IMS and high mass resolution are used for accurate assignment of molecular formulae.

Performance analysis of an integrated GPS/inertial attitude determination system. M.S. Thesis - MIT

NASA Technical Reports Server (NTRS)

Sullivan, Wendy I.

1994-01-01

The performance of an integrated GPS/inertial attitude determination system is investigated using a linear covariance analysis. The principles of GPS interferometry are reviewed, and the major error sources of both interferometers and gyroscopes are discussed and modeled. A new figure of merit, attitude dilution of precision (ADOP), is defined for two possible GPS attitude determination methods, namely single difference and double difference interferometry. Based on this figure of merit, a satellite selection scheme is proposed. The performance of the integrated GPS/inertial attitude determination system is determined using a linear covariance analysis. Based on this analysis, it is concluded that the baseline errors (i.e., knowledge of the GPS interferometer baseline relative to the vehicle coordinate system) are the limiting factor in system performance. By reducing baseline errors, it should be possible to use lower quality gyroscopes without significantly reducing performance. For the cases considered, single difference interferometry is only marginally better than double difference interferometry. Finally, the performance of the system is found to be relatively insensitive to the satellite selection technique.

Integrated communication and control systems. I - Analysis

NASA Technical Reports Server (NTRS)

Halevi, Yoram; Ray, Asok

1988-01-01

The paper presents the results of an ICCS analysis focusing on discrete-time control systems subject to time-varying delays. The present analytical technique is applicable to integrated dynamic systems such as those encountered in advanced aircraft, spacecraft, and the real-time control of robots and machine tools via a high-speed network within an autonomous manufacturing environment. The significance of data latency and missynchronization between individual system components in ICCS networks is discussed in view of the time-varying delays.

The Structure and Effectiveness of Health Systems: Exploring the Impact of System Integration in Rural China.

PubMed

Wang, Xin; Birch, Stephen; Ma, Huifen; Zhu, Weiming; Meng, Qingyue

2016-08-12

Facing the challenges of aging populations, increasing chronic diseases prevalence and health system fragmentation, there have been several pilots of integrated health systems in China. But little is known about their structure, mechanism and effectiveness. The aim of this paper is to analyze health system integration and develop recommendations for achieving integration. Huangzhong and Hualong counties in Qinghai province were studied as study sites, with only Huangzhong having implemented health system integration. Questionnaires, interviews, and health insurance records were sources of data. Social network analysis was employed to analyze integration, through structure measurement and effectiveness evaluation. Health system integration in Huangzhong is higher than in Hualong, so is system effectiveness. The patient referral network in Hualong has more "leapfrog" referrals. The information sharing networks in both counties are larger than the other types of networks. The average distance in the joint training network of Huangzhong is less than in Hualong. Meanwhile, there are deficiencies common to both systems. Both county health systems have strengths and limitations regarding system integration. The use of medical consortia in Huangzhong has contributed to system effectiveness. Future research might consider alternative more context specific models of health system integration.

NASA Lighting Research, Test, & Analysis

NASA Technical Reports Server (NTRS)

Clark, Toni

2015-01-01

The Habitability and Human Factors Branch, at Johnson Space Center, in Houston, TX, provides technical guidance for the development of spaceflight lighting requirements, verification of light system performance, analysis of integrated environmental lighting systems, and research of lighting-related human performance issues. The Habitability & Human Factors Lighting Team maintains two physical facilities that are integrated to provide support. The Lighting Environment Test Facility (LETF) provides a controlled darkroom environment for physical verification of lighting systems with photometric and spetrographic measurement systems. The Graphics Research & Analysis Facility (GRAF) maintains the capability for computer-based analysis of operational lighting environments. The combined capabilities of the Lighting Team at Johnson Space Center have been used for a wide range of lighting-related issues.

Safety impact of an integrated crash warning system based on field test data.

DOT National Transportation Integrated Search

2011-06-13

This paper provides the results of an analysis : conducted to assess the safety impact of an integrated : vehicle-based crash warning system based on : naturalistic driving data collected from a field : operational test. The system incorporates four ...

Integrated corridor management analysis, modeling, and simulation for the I–15 corridor in San Diego, California—post-deployment analysis plan.

DOT National Transportation Integrated Search

2016-11-01

Post-Deployment Analysis, Modeling, and Simulation (AMS) activities focus on identifying impacts and benefits of the as-deployed Integrated Corridor Management (ICM) system. The as-deployed ICM strategies may differ from as-planned ...

Integrated corridor management : analysis, modeling, and simulation for the U.S.-15 corridor in Dallas, Texas—post-deployment analysis plan.

DOT National Transportation Integrated Search

2016-10-01

Post-Deployment Analysis, Modeling, and Simulation (AMS) activities focus on identifying impacts and benefits of the as-deployed Integrated Corridor Management (ICM) system. The as-deployed ICM strategies may differ from as-planned ...

Expert system for web based collaborative CAE

NASA Astrophysics Data System (ADS)

Hou, Liang; Lin, Zusheng

2006-11-01

An expert system for web based collaborative CAE was developed based on knowledge engineering, relational database and commercial FEA (Finite element analysis) software. The architecture of the system was illustrated. In this system, the experts' experiences, theories and typical examples and other related knowledge, which will be used in the stage of pre-process in FEA, were categorized into analysis process and object knowledge. Then, the integrated knowledge model based on object-oriented method and rule based method was described. The integrated reasoning process based on CBR (case based reasoning) and rule based reasoning was presented. Finally, the analysis process of this expert system in web based CAE application was illustrated, and an analysis example of a machine tool's column was illustrated to prove the validity of the system.

MDAS: an integrated system for metabonomic data analysis.

PubMed

Liu, Juan; Li, Bo; Xiong, Jiang-Hui

2009-03-01

Metabonomics, the latest 'omics' research field, shows great promise as a tool in biomarker discovery, drug efficacy and toxicity analysis, disease diagnosis and prognosis. One of the major challenges now facing researchers is how to process this data to yield useful information about a biological system, e.g., the mechanism of diseases. Traditional methods employed in metabonomic data analysis use multivariate analysis methods developed independently in chemometrics research. Additionally, with the development of machine learning approaches, some methods such as SVMs also show promise for use in metabonomic data analysis. Aside from the application of general multivariate analysis and machine learning methods to this problem, there is also a need for an integrated tool customized for metabonomic data analysis which can be easily used by biologists to reveal interesting patterns in metabonomic data.In this paper, we present a novel software tool MDAS (Metabonomic Data Analysis System) for metabonomic data analysis which integrates traditional chemometrics methods and newly introduced machine learning approaches. MDAS contains a suite of functional models for metabonomic data analysis and optimizes the flow of data analysis. Several file formats can be accepted as input. The input data can be optionally preprocessed and can then be processed with operations such as feature analysis and dimensionality reduction. The data with reduced dimensionalities can be used for training or testing through machine learning models. The system supplies proper visualization for data preprocessing, feature analysis, and classification which can be a powerful function for users to extract knowledge from the data. MDAS is an integrated platform for metabonomic data analysis, which transforms a complex analysis procedure into a more formalized and simplified one. The software package can be obtained from the authors.

Integrated Library Systems in Canadian Public, Academic and Special Libraries: Fourth Annual Survey.

ERIC Educational Resources Information Center

Merilees, Bobbie

1990-01-01

Reports the results of a survey of integrated library system vendors that examined installations in Canadian academic, public and special libraries during 1989. Findings discussed include large library system versus PC-based system market shares, an analysis of system selection by type of library, and other factors that affect system selection. A…

Requirements Analysis for Information-Intensive Systems

NASA Technical Reports Server (NTRS)

Callender, E. D.; Hartsough, C.; Morris, R. V.; Yamamoto, Y.

1986-01-01

Report discusses role of requirements analysis in development of information-intensive systems. System examined from variety of human viewpoints during design, development, and implementation. Such examination, called requirements analysis, ensures system simultaneously meets number of distinct but interacting needs. Viewpoints defined and integrated to help attain objectives.

An Integrated Analysis of the Physiological Effects of Space Flight: Executive Summary

NASA Technical Reports Server (NTRS)

Leonard, J. I.

1985-01-01

A large array of models were applied in a unified manner to solve problems in space flight physiology. Mathematical simulation was used as an alternative way of looking at physiological systems and maximizing the yield from previous space flight experiments. A medical data analysis system was created which consist of an automated data base, a computerized biostatistical and data analysis system, and a set of simulation models of physiological systems. Five basic models were employed: (1) a pulsatile cardiovascular model; (2) a respiratory model; (3) a thermoregulatory model; (4) a circulatory, fluid, and electrolyte balance model; and (5) an erythropoiesis regulatory model. Algorithms were provided to perform routine statistical tests, multivariate analysis, nonlinear regression analysis, and autocorrelation analysis. Special purpose programs were prepared for rank correlation, factor analysis, and the integration of the metabolic balance data.

Integration of targeted health interventions into health systems: a conceptual framework for analysis.

PubMed

Atun, Rifat; de Jongh, Thyra; Secci, Federica; Ohiri, Kelechi; Adeyi, Olusoji

2010-03-01

The benefits of integrating programmes that emphasize specific interventions into health systems to improve health outcomes have been widely debated. This debate has been driven by narrow binary considerations of integrated (horizontal) versus non-integrated (vertical) programmes, and characterized by polarization of views with protagonists for and against integration arguing the relative merits of each approach. The presence of both integrated and non-integrated programmes in many countries suggests benefits to each approach. While the terms 'vertical' and 'integrated' are widely used, they each describe a range of phenomena. In practice the dichotomy between vertical and horizontal is not rigid and the extent of verticality or integration varies between programmes. However, systematic analysis of the relative merits of integration in various contexts and for different interventions is complicated as there is no commonly accepted definition of 'integration'-a term loosely used to describe a variety of organizational arrangements for a range of programmes in different settings. We present an analytical framework which enables deconstruction of the term integration into multiple facets, each corresponding to a critical health system function. Our conceptual framework builds on theoretical propositions and empirical research in innovation studies, and in particular adoption and diffusion of innovations within health systems, and builds on our own earlier empirical research. It brings together the critical elements that affect adoption, diffusion and assimilation of a health intervention, and in doing so enables systematic and holistic exploration of the extent to which different interventions are integrated in varied settings and the reasons for the variation. The conceptual framework and the analytical approach we propose are intended to facilitate analysis in evaluative and formative studies of-and policies on-integration, for use in systematically comparing and contrasting health interventions in a country or in different settings to generate meaningful evidence to inform policy.

Strategic Mobility 21: Integrated Tracking System Analysis and Concept Design

DTIC Science & Technology

2007-08-31

public and foreign nationals, companies, and governments , including adversary governments , and may be exported. c. This statement may not be used on...42 ii Integrated Tracking System Analysis & Concept Design LIST OF FIGURES Figure 1: Southern California Association of Governments ...conducted under the auspices of the California State University – Long Beach Foundation, a government -industry academic collaborative enterprise

Grid connected integrated community energy system. Phase II: final state 2 report. Cost benefit analysis, operating costs and computer simulation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1978-03-22

A grid-connected Integrated Community Energy System (ICES) with a coal-burning power plant located on the University of Minnesota campus is planned. The cost benefit analysis performed for this ICES, the cost accounting methods used, and a computer simulation of the operation of the power plant are described. (LCL)

Mechatronic System Design Course for Undergraduate Programmes

ERIC Educational Resources Information Center

Saleem, A.; Tutunji, T.; Al-Sharif, L.

2011-01-01

Technology advancement and human needs have led to integration among many engineering disciplines. Mechatronics engineering is an integrated discipline that focuses on the design and analysis of complete engineering systems. These systems include mechanical, electrical, computer and control subsystems. In this paper, the importance of teaching…

A 3D Human-Machine Integrated Design and Analysis Framework for Squat Exercises with a Smith Machine.

PubMed

Lee, Haerin; Jung, Moonki; Lee, Ki-Kwang; Lee, Sang Hun

2017-02-06

In this paper, we propose a three-dimensional design and evaluation framework and process based on a probabilistic-based motion synthesis algorithm and biomechanical analysis system for the design of the Smith machine and squat training programs. Moreover, we implemented a prototype system to validate the proposed framework. The framework consists of an integrated human-machine-environment model as well as a squat motion synthesis system and biomechanical analysis system. In the design and evaluation process, we created an integrated model in which interactions between a human body and machine or the ground are modeled as joints with constraints at contact points. Next, we generated Smith squat motion using the motion synthesis program based on a Gaussian process regression algorithm with a set of given values for independent variables. Then, using the biomechanical analysis system, we simulated joint moments and muscle activities from the input of the integrated model and squat motion. We validated the model and algorithm through physical experiments measuring the electromyography (EMG) signals, ground forces, and squat motions as well as through a biomechanical simulation of muscle forces. The proposed approach enables the incorporation of biomechanics in the design process and reduces the need for physical experiments and prototypes in the development of training programs and new Smith machines.

A 3D Human-Machine Integrated Design and Analysis Framework for Squat Exercises with a Smith Machine

PubMed Central

Lee, Haerin; Jung, Moonki; Lee, Ki-Kwang; Lee, Sang Hun

2017-01-01

In this paper, we propose a three-dimensional design and evaluation framework and process based on a probabilistic-based motion synthesis algorithm and biomechanical analysis system for the design of the Smith machine and squat training programs. Moreover, we implemented a prototype system to validate the proposed framework. The framework consists of an integrated human–machine–environment model as well as a squat motion synthesis system and biomechanical analysis system. In the design and evaluation process, we created an integrated model in which interactions between a human body and machine or the ground are modeled as joints with constraints at contact points. Next, we generated Smith squat motion using the motion synthesis program based on a Gaussian process regression algorithm with a set of given values for independent variables. Then, using the biomechanical analysis system, we simulated joint moments and muscle activities from the input of the integrated model and squat motion. We validated the model and algorithm through physical experiments measuring the electromyography (EMG) signals, ground forces, and squat motions as well as through a biomechanical simulation of muscle forces. The proposed approach enables the incorporation of biomechanics in the design process and reduces the need for physical experiments and prototypes in the development of training programs and new Smith machines. PMID:28178184

Integration of a satellite ground support system based on analysis of the satellite ground support domain

NASA Technical Reports Server (NTRS)

Pendley, R. D.; Scheidker, E. J.; Levitt, D. S.; Myers, C. R.; Werking, R. D.

1994-01-01

This analysis defines a complete set of ground support functions based on those practiced in real space flight operations during the on-orbit phase of a mission. These functions are mapped against ground support functions currently in use by NASA and DOD. Software components to provide these functions can be hosted on RISC-based work stations and integrated to provide a modular, integrated ground support system. Such modular systems can be configured to provide as much ground support functionality as desired. This approach to ground systems has been widely proposed and prototyped both by government institutions and commercial vendors. The combined set of ground support functions we describe can be used as a standard to evaluate candidate ground systems. This approach has also been used to develop a prototype of a modular, loosely-integrated ground support system, which is discussed briefly. A crucial benefit to a potential user is that all the components are flight-qualified, thus giving high confidence in their accuracy and reliability.

Integration of a satellite ground support system based on analysis of the satellite ground support domain

NASA Astrophysics Data System (ADS)

Pendley, R. D.; Scheidker, E. J.; Levitt, D. S.; Myers, C. R.; Werking, R. D.

1994-11-01

This analysis defines a complete set of ground support functions based on those practiced in real space flight operations during the on-orbit phase of a mission. These functions are mapped against ground support functions currently in use by NASA and DOD. Software components to provide these functions can be hosted on RISC-based work stations and integrated to provide a modular, integrated ground support system. Such modular systems can be configured to provide as much ground support functionality as desired. This approach to ground systems has been widely proposed and prototyped both by government institutions and commercial vendors. The combined set of ground support functions we describe can be used as a standard to evaluate candidate ground systems. This approach has also been used to develop a prototype of a modular, loosely-integrated ground support system, which is discussed briefly. A crucial benefit to a potential user is that all the components are flight-qualified, thus giving high confidence in their accuracy and reliability.

Propulsion system/flight control integration for supersonic aircraft

NASA Technical Reports Server (NTRS)

Reukauf, P. J.; Burcham, F. W., Jr.

1976-01-01

Digital integrated control systems are studied. Such systems allow minimization of undesirable interactions while maximizing performance at all flight conditions. One such program is the YF-12 cooperative control program. The existing analog air data computer, autothrottle, autopilot, and inlet control systems are converted to digital systems by using a general purpose airborne computer and interface unit. Existing control laws are programed and tested in flight. Integrated control laws, derived using accurate mathematical models of the airplane and propulsion system in conjunction with modern control techniques, are tested in flight. Analysis indicates that an integrated autothrottle autopilot gives good flight path control and that observers are used to replace failed sensors.

IWRM Policy in Colombia, drawbacks and strategies towards integration

NASA Astrophysics Data System (ADS)

Cardona, C. A.

2016-12-01

Since the establishment of the Integrated Water Resource Management National Policy in Colombia in 2010- IWRMNP, several initiatives has been developed in order to understand and manage water within the integration perspective. However, the Colombian institutional and legal frameworks do not favor the implementation of integrated management exercises, and many efforts have been fruitless in recent years. Additionally, there is an avalanche of techniques and available technologies to develop integrated models, analysis or assessments, which frequently are interpreted as the same tool. An analysis of the Colombian context in regulatory terms and institutions involved is carried out, as a prelude to address the topic of analysis modeling and integrated management. Moreover, in Colombian legislation there exists policies regarding integrated soil management, integrated biodiversity management, as well as several current international trends such as integrated landscape planning, integrated urban areas management etc. Therefore, and in light of the initial analysis, a discussion of redundancy or complementarity of such management it is carried out. Finally, a strategy is proposed for decision makers of local and regional level, trying to overcome technical gaps left by national policy and regulations. This is done from a discussion of the various anthropic damages to water resources systems. Also a classification of integrated models is proposed and a general approach to systems integrated resource management to finally present a state- management matrix methodology applicable to different cases and management requirements. The results of its implementation in a small basin is presented.

Development and Application of an Integrated Approach toward NASA Airspace Systems Research

NASA Technical Reports Server (NTRS)

Barhydt, Richard; Fong, Robert K.; Abramson, Paul D.; Koenke, Ed

2008-01-01

The National Aeronautics and Space Administration's (NASA) Airspace Systems Program is contributing air traffic management research in support of the 2025 Next Generation Air Transportation System (NextGen). Contributions support research and development needs provided by the interagency Joint Planning and Development Office (JPDO). These needs generally call for integrated technical solutions that improve system-level performance and work effectively across multiple domains and planning time horizons. In response, the Airspace Systems Program is pursuing an integrated research approach and has adapted systems engineering best practices for application in a research environment. Systems engineering methods aim to enable researchers to methodically compare different technical approaches, consider system-level performance, and develop compatible solutions. Systems engineering activities are performed iteratively as the research matures. Products of this approach include a demand and needs analysis, system-level descriptions focusing on NASA research contributions, system assessment and design studies, and common systemlevel metrics, scenarios, and assumptions. Results from the first systems engineering iteration include a preliminary demand and needs analysis; a functional modeling tool; and initial system-level metrics, scenario characteristics, and assumptions. Demand and needs analysis results suggest that several advanced concepts can mitigate demand/capacity imbalances for NextGen, but fall short of enabling three-times current-day capacity at the nation s busiest airports and airspace. Current activities are focusing on standardizing metrics, scenarios, and assumptions, conducting system-level performance assessments of integrated research solutions, and exploring key system design interfaces.

ISSYS: An integrated synergistic Synthesis System

NASA Technical Reports Server (NTRS)

Dovi, A. R.

1980-01-01

Integrated Synergistic Synthesis System (ISSYS), an integrated system of computer codes in which the sequence of program execution and data flow is controlled by the user, is discussed. The commands available to exert such control, the ISSYS major function and rules, and the computer codes currently available in the system are described. Computational sequences frequently used in the aircraft structural analysis and synthesis are defined. External computer codes utilized by the ISSYS system are documented. A bibliography on the programs is included.

Human performance cognitive-behavioral modeling: a benefit for occupational safety.

PubMed

Gore, Brian F

2002-01-01

Human Performance Modeling (HPM) is a computer-aided job analysis software methodology used to generate predictions of complex human-automation integration and system flow patterns with the goal of improving operator and system safety. The use of HPM tools has recently been increasing due to reductions in computational cost, augmentations in the tools' fidelity, and usefulness in the generated output. An examination of an Air Man-machine Integration Design and Analysis System (Air MIDAS) model evaluating complex human-automation integration currently underway at NASA Ames Research Center will highlight the importance to occupational safety of considering both cognitive and physical aspects of performance when researching human error.

Use of the MATRIXx Integrated Toolkit on the Microwave Anisotropy Probe Attitude Control System

NASA Technical Reports Server (NTRS)

Ward, David K.; Andrews, Stephen F.; McComas, David C.; ODonnell, James R., Jr.

1999-01-01

Recent advances in analytical software tools allow the analysis, simulation, flight code, and documentation of an algorithm to be generated from a single source, all within one integrated analytical design package. NASA's Microwave Anisotropy Probe project has used one such package, Integrated Systems' MATRIXx suite, in the design of the spacecraft's Attitude Control System. The project's experience with the linear analysis, simulation, code generation, and documentation tools will be presented and compared with more traditional development tools. In particular, the quality of the flight software generated will be examined in detail. Finally, lessons learned on each of the tools will be shared.

Human performance cognitive-behavioral modeling: a benefit for occupational safety

NASA Technical Reports Server (NTRS)

Gore, Brian F.

2002-01-01

Human Performance Modeling (HPM) is a computer-aided job analysis software methodology used to generate predictions of complex human-automation integration and system flow patterns with the goal of improving operator and system safety. The use of HPM tools has recently been increasing due to reductions in computational cost, augmentations in the tools' fidelity, and usefulness in the generated output. An examination of an Air Man-machine Integration Design and Analysis System (Air MIDAS) model evaluating complex human-automation integration currently underway at NASA Ames Research Center will highlight the importance to occupational safety of considering both cognitive and physical aspects of performance when researching human error.

Integration of Multifidelity Multidisciplinary Computer Codes for Design and Analysis of Supersonic Aircraft

NASA Technical Reports Server (NTRS)

Geiselhart, Karl A.; Ozoroski, Lori P.; Fenbert, James W.; Shields, Elwood W.; Li, Wu

2011-01-01

This paper documents the development of a conceptual level integrated process for design and analysis of efficient and environmentally acceptable supersonic aircraft. To overcome the technical challenges to achieve this goal, a conceptual design capability which provides users with the ability to examine the integrated solution between all disciplines and facilitates the application of multidiscipline design, analysis, and optimization on a scale greater than previously achieved, is needed. The described capability is both an interactive design environment as well as a high powered optimization system with a unique blend of low, mixed and high-fidelity engineering tools combined together in the software integration framework, ModelCenter. The various modules are described and capabilities of the system are demonstrated. The current limitations and proposed future enhancements are also discussed.

A study on spatial decision support systems for HIV/AIDS prevention based on COM GIS technology

NASA Astrophysics Data System (ADS)

Yang, Kun; Luo, Huasong; Peng, Shungyun; Xu, Quanli

2007-06-01

Based on the deeply analysis of the current status and the existing problems of GIS technology applications in Epidemiology, this paper has proposed the method and process for establishing the spatial decision support systems of AIDS epidemic prevention by integrating the COM GIS, Spatial Database, GPS, Remote Sensing, and Communication technologies, as well as ASP and ActiveX software development technologies. One of the most important issues for constructing the spatial decision support systems of AIDS epidemic prevention is how to integrate the AIDS spreading models with GIS. The capabilities of GIS applications in the AIDS epidemic prevention have been described here in this paper firstly. Then some mature epidemic spreading models have also been discussed for extracting the computation parameters. Furthermore, a technical schema has been proposed for integrating the AIDS spreading models with GIS and relevant geospatial technologies, in which the GIS and model running platforms share a common spatial database and the computing results can be spatially visualized on Desktop or Web GIS clients. Finally, a complete solution for establishing the decision support systems of AIDS epidemic prevention has been offered in this paper based on the model integrating methods and ESRI COM GIS software packages. The general decision support systems are composed of data acquisition sub-systems, network communication sub-systems, model integrating sub-systems, AIDS epidemic information spatial database sub-systems, AIDS epidemic information querying and statistical analysis sub-systems, AIDS epidemic dynamic surveillance sub-systems, AIDS epidemic information spatial analysis and decision support sub-systems, as well as AIDS epidemic information publishing sub-systems based on Web GIS.

An integratable microfluidic cartridge for forensic swab samples lysis.

PubMed

Yang, Jianing; Brooks, Carla; Estes, Matthew D; Hurth, Cedric M; Zenhausern, Frederic

2014-01-01

Fully automated rapid forensic DNA analysis requires integrating several multistep processes onto a single microfluidic platform, including substrate lysis, extraction of DNA from the released lysate solution, multiplexed PCR amplification of STR loci, separation of PCR products by capillary electrophoresis, and analysis for allelic peak calling. Over the past several years, most of the rapid DNA analysis systems developed started with the reference swab sample lysate and involved an off-chip lysis of collected substrates. As a result of advancement in technology and chemistry, addition of a microfluidic module for swab sample lysis has been achieved in a few of the rapid DNA analysis systems. However, recent reports on integrated rapid DNA analysis systems with swab-in and answer-out capability lack any quantitative and qualitative characterization of the swab-in sample lysis module, which is important for downstream forensic sample processing. Maximal collection and subsequent recovery of the biological material from the crime scene is one of the first and critical steps in forensic DNA technology. Herein we present the design, fabrication and characterization of an integratable swab lysis cartridge module and the test results obtained from different types of commonly used forensic swab samples, including buccal, saliva, and blood swab samples, demonstrating the compatibility with different downstream DNA extraction chemistries. This swab lysis cartridge module is easy to operate, compatible with both forensic and microfluidic requirements, and ready to be integrated with our existing automated rapid forensic DNA analysis system. Following the characterization of the swab lysis module, an integrated run from buccal swab sample-in to the microchip CE electropherogram-out was demonstrated on the integrated prototype instrument. Therefore, in this study, we demonstrate that this swab lysis cartridge module is: (1) functionally, comparable with routine benchtop lysis, (2) compatible with various types of swab samples and chemistries, and (3) integratable to achieve a micro total analysis system (μTAS) for rapid DNA analysis. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

Computational System For Rapid CFD Analysis In Engineering

NASA Technical Reports Server (NTRS)

Barson, Steven L.; Ascoli, Edward P.; Decroix, Michelle E.; Sindir, Munir M.

1995-01-01

Computational system comprising modular hardware and software sub-systems developed to accelerate and facilitate use of techniques of computational fluid dynamics (CFD) in engineering environment. Addresses integration of all aspects of CFD analysis process, including definition of hardware surfaces, generation of computational grids, CFD flow solution, and postprocessing. Incorporates interfaces for integration of all hardware and software tools needed to perform complete CFD analysis. Includes tools for efficient definition of flow geometry, generation of computational grids, computation of flows on grids, and postprocessing of flow data. System accepts geometric input from any of three basic sources: computer-aided design (CAD), computer-aided engineering (CAE), or definition by user.

Integrated risk assessment and screening analysis of drinking water safety of a conventional water supply system.

PubMed

Sun, F; Chen, J; Tong, Q; Zeng, S

2007-01-01

Management of drinking water safety is changing towards an integrated risk assessment and risk management approach that includes all processes in a water supply system from catchment to consumers. However, given the large number of water supply systems in China and the cost of implementing such a risk assessment procedure, there is a necessity to first conduct a strategic screening analysis at a national level. An integrated methodology of risk assessment and screening analysis is thus proposed to evaluate drinking water safety of a conventional water supply system. The violation probability, indicating drinking water safety, is estimated at different locations of a water supply system in terms of permanganate index, ammonia nitrogen, turbidity, residual chlorine and trihalomethanes. Critical parameters with respect to drinking water safety are then identified, based on which an index system is developed to prioritize conventional water supply systems in implementing a detailed risk assessment procedure. The evaluation results are represented as graphic check matrices for the concerned hazards in drinking water, from which the vulnerability of a conventional water supply system is characterized.

Development of an integrated configuration management/flight director system for piloted STOL approaches

NASA Technical Reports Server (NTRS)

Hoh, R. H.; Klein, R. H.; Johnson, W. A.

1977-01-01

A system analysis method for the development of an integrated configuration management/flight director system for IFR STOL approaches is presented. Curved descending decelerating approach trajectories are considered. Considerable emphasis is placed on satisfying the pilot centered requirements (acceptable workload) as well as the usual guidance and control requirements (acceptable performance). The Augmentor Wing Jet STOL Research Aircraft was utilized to allow illustration by example, and to validate the analysis procedure via manned simulation.

Integrated system for automated financial document processing

NASA Astrophysics Data System (ADS)

Hassanein, Khaled S.; Wesolkowski, Slawo; Higgins, Ray; Crabtree, Ralph; Peng, Antai

1997-02-01

A system was developed that integrates intelligent document analysis with multiple character/numeral recognition engines in order to achieve high accuracy automated financial document processing. In this system, images are accepted in both their grayscale and binary formats. A document analysis module starts by extracting essential features from the document to help identify its type (e.g. personal check, business check, etc.). These features are also utilized to conduct a full analysis of the image to determine the location of interesting zones such as the courtesy amount and the legal amount. These fields are then made available to several recognition knowledge sources such as courtesy amount recognition engines and legal amount recognition engines through a blackboard architecture. This architecture allows all the available knowledge sources to contribute incrementally and opportunistically to the solution of the given recognition query. Performance results on a test set of machine printed business checks using the integrated system are also reported.

Train integrity detection risk analysis based on PRISM

NASA Astrophysics Data System (ADS)

Wen, Yuan

2018-04-01

GNSS based Train Integrity Monitoring System (TIMS) is an effective and low-cost detection scheme for train integrity detection. However, as an external auxiliary system of CTCS, GNSS may be influenced by external environments, such as uncertainty of wireless communication channels, which may lead to the failure of communication and positioning. In order to guarantee the reliability and safety of train operation, a risk analysis method of train integrity detection based on PRISM is proposed in this article. First, we analyze the risk factors (in GNSS communication process and the on-board communication process) and model them. Then, we evaluate the performance of the model in PRISM based on the field data. Finally, we discuss how these risk factors influence the train integrity detection process.

Fourth Coast-Seaway Systems Requirements Analysis : Volume I - The Role of an Integrated Marine Traffic Information and Control System

DOT National Transportation Integrated Search

1972-03-24

This report summarizes the need for an Integrated Marine Traffic Informaiton and Control System (IMTIC) in the St. Lawrence Seaway. The analytic emphasis is on the Welland Canal to Gulf of St. Lawrence portion of the Seaway system. The Upper Great La...

Integrating NASA's Land Analysis System (LAS) image processing software with an appropriate Geographic Information System (GIS): A review of candidates in the public domain

NASA Technical Reports Server (NTRS)

Rochon, Gilbert L.

1989-01-01

A user requirements analysis (URA) was undertaken to determine and appropriate public domain Geographic Information System (GIS) software package for potential integration with NASA's LAS (Land Analysis System) 5.0 image processing system. The necessity for a public domain system was underscored due to the perceived need for source code access and flexibility in tailoring the GIS system to the needs of a heterogenous group of end-users, and to specific constraints imposed by LAS and its user interface, Transportable Applications Executive (TAE). Subsequently, a review was conducted of a variety of public domain GIS candidates, including GRASS 3.0, MOSS, IEMIS, and two university-based packages, IDRISI and KBGIS. The review method was a modified version of the GIS evaluation process, development by the Federal Interagency Coordinating Committee on Digital Cartography. One IEMIS-derivative product, the ALBE (AirLand Battlefield Environment) GIS, emerged as the most promising candidate for integration with LAS. IEMIS (Integrated Emergency Management Information System) was developed by the Federal Emergency Management Agency (FEMA). ALBE GIS is currently under development at the Pacific Northwest Laboratory under contract with the U.S. Army Corps of Engineers' Engineering Topographic Laboratory (ETL). Accordingly, recommendations are offered with respect to a potential LAS/ALBE GIS linkage and with respect to further system enhancements, including coordination with the development of the Spatial Analysis and Modeling System (SAMS) GIS in Goddard's IDM (Intelligent Data Management) developments in Goddard's National Space Science Data Center.

The Integrated Farm System Model: A Tool for Whole Farm Nutrient Management Analysis

USDA-ARS?s Scientific Manuscript database

With tighter profit margins and increasing environmental constraints, strategic planning of farm production systems is becoming both more important and more difficult. This is especially true for integrated crop and animal production systems. Animal production is complex with a number of interacting...

PAVECHECK : integrating deflection and GPR for network condition surveys.

DOT National Transportation Integrated Search

2009-01-01

The PAVECHECK data integration and analysis system was developed to merge Falling Weight : Deflectometer (FWD) and Ground Penetrating Radar (GPR) data together with digital video images of : surface conditions. In this study Global Positioning System...

Army-NASA aircrew/aircraft integration program: Phase 4 A(3)I Man-Machine Integration Design and Analysis System (MIDAS) software detailed design document

NASA Technical Reports Server (NTRS)

Banda, Carolyn; Bushnell, David; Chen, Scott; Chiu, Alex; Constantine, Betsy; Murray, Jerry; Neukom, Christian; Prevost, Michael; Shankar, Renuka; Staveland, Lowell

1991-01-01

The Man-Machine Integration Design and Analysis System (MIDAS) is an integrated suite of software components that constitutes a prototype workstation to aid designers in applying human factors principles to the design of complex human-machine systems. MIDAS is intended to be used at the very early stages of conceptual design to provide an environment wherein designers can use computational representations of the crew station and operator, instead of hardware simulators and man-in-the-loop studies, to discover problems and ask 'what if' questions regarding the projected mission, equipment, and environment. This document is the Software Product Specification for MIDAS. Introductory descriptions of the processing requirements, hardware/software environment, structure, I/O, and control are given in the main body of the document for the overall MIDAS system, with detailed discussion of the individual modules included in Annexes A-J.

Evaluation of automated decisionmaking methodologies and development of an integrated robotic system simulation, volume 2, part 1. Appendix A: Software documentation

NASA Technical Reports Server (NTRS)

Lowrie, J. W.; Fermelia, A. J.; Haley, D. C.; Gremban, K. D.; Vanbaalen, J.; Walsh, R. W.

1982-01-01

Documentation of the preliminary software developed as a framework for a generalized integrated robotic system simulation is presented. The program structure is composed of three major functions controlled by a program executive. The three major functions are: system definition, analysis tools, and post processing. The system definition function handles user input of system parameters and definition of the manipulator configuration. The analysis tools function handles the computational requirements of the program. The post processing function allows for more detailed study of the results of analysis tool function executions. Also documented is the manipulator joint model software to be used as the basis of the manipulator simulation which will be part of the analysis tools capability.

Enhancement/upgrade of Engine Structures Technology Best Estimator (EST/BEST) Software System

NASA Technical Reports Server (NTRS)

Shah, Ashwin

2003-01-01

This report describes the work performed during the contract period and the capabilities included in the EST/BEST software system. The developed EST/BEST software system includes the integrated NESSUS, IPACS, COBSTRAN, and ALCCA computer codes required to perform the engine cycle mission and component structural analysis. Also, the interactive input generator for NESSUS, IPACS, and COBSTRAN computer codes have been developed and integrated with the EST/BEST software system. The input generator allows the user to create input from scratch as well as edit existing input files interactively. Since it has been integrated with the EST/BEST software system, it enables the user to modify EST/BEST generated files and perform the analysis to evaluate the benefits. Appendix A gives details of how to use the newly added features in the EST/BEST software system.

Neurocognitive mechanisms of perception-action coordination: a review and theoretical integration.

PubMed

Ridderinkhof, K Richard

2014-10-01

The present analysis aims at a theoretical integration of, and a systems-neuroscience perspective on, a variety of historical and contemporary views on perception-action coordination (PAC). We set out to determine the common principles or lawful linkages between sensory and motor systems that explain how perception is action-oriented and how action is perceptually guided. To this end, we analyze the key ingredients to such an integrated framework, examine the architecture of dual-system conjectures of PAC, and endeavor in an historical analysis of the key characteristics, mechanisms, and phenomena of PACs. This analysis will reveal that dual-systems views are in need of fundamental re-thinking, and its elements will be amalgamated with current views on action-oriented predictive processing into a novel integrative theoretical framework (IMPPACT: Impetus, Motivation, and Prediction in Perception-Action Coordination theory). From this framework and its neurocognitive architecture we derive a number of non-trivial predictions regarding conative, motive-driven PAC. We end by presenting a brief outlook on how IMPPACT might present novel insights into certain pathologies and into action expertise. Copyright © 2014 Elsevier Ltd. All rights reserved.

Integrated multiplexed capillary electrophoresis system

DOEpatents

Yeung, Edward S.; Tan, Hongdong

2002-05-14

The present invention provides an integrated multiplexed capillary electrophoresis system for the analysis of sample analytes. The system integrates and automates multiple components, such as chromatographic columns and separation capillaries, and further provides a detector for the detection of analytes eluting from the separation capillaries. The system employs multiplexed freeze/thaw valves to manage fluid flow and sample movement. The system is computer controlled and is capable of processing samples through reaction, purification, denaturation, pre-concentration, injection, separation and detection in parallel fashion. Methods employing the system of the invention are also provided.

Polarity management: the key challenge for integrated health systems.

PubMed

Burns, L R

1999-01-01

Integrated health systems are confronted with numerous dilemmas that must be managed. Many of these dilemmas are an inherent part of the system's structure, given that multiple competing hospitals, medical groups, and (sometimes) health plans are often under one organizational roof. This article presents an analysis of these dilemmas--referred to in the management literature as polarities--as they are found in six integrated health systems in Illinois. The nine polarities that must be managed include (1) hospital systems that want to be organizations of physicians; (2) system expansion by growing the physician component; (3) system centralization and physician decentralization; (4) centripetal and centrifugal forces involving physicians; (5) system objectives and physician interests; (6) system centralization and hospital decentralization; (7) primary care physicians and specialists; (8) physician autonomy via collectivization; and (9) vertical and virtual integration. The article identifies some of the solutions to the polarities that have been enacted by systems. In general, executives and physicians in integrated health systems must attend to the processes of integration as much as or more than the structures of integration.

Development of a web-based epidemiological surveillance system with health system response for improving maternal and newborn health: Field-testing in Thailand.

PubMed

Liabsuetrakul, Tippawan; Prappre, Tagoon; Pairot, Pakamas; Oumudee, Nurlisa; Islam, Monir

2017-06-01

Surveillance systems are yet to be integrated with health information systems for improving the health of pregnant mothers and their newborns, particularly in developing countries. This study aimed to develop a web-based epidemiological surveillance system for maternal and newborn health with integration of action-oriented responses and automatic data analysis with results presentations and to assess the system acceptance by nurses and doctors involved in various hospitals in southern Thailand. Freeware software and scripting languages were used. The system can be run on different platforms, and it is accessible via various electronic devices. Automatic data analysis with results presentations in the forms of graphs, tables and maps was part of the system. A multi-level security system was incorporated into the program. Most doctors and nurses involved in the study felt the system was easy to use and useful. This system can be integrated into country routine reporting system for monitoring maternal and newborn health and survival.

The Integrated Hazard Analysis Integrator

NASA Technical Reports Server (NTRS)

Morris, A. Terry; Massie, Michael J.

2009-01-01

Hazard analysis addresses hazards that arise in the design, development, manufacturing, construction, facilities, transportation, operations and disposal activities associated with hardware, software, maintenance, operations and environments. An integrated hazard is an event or condition that is caused by or controlled by multiple systems, elements, or subsystems. Integrated hazard analysis (IHA) is especially daunting and ambitious for large, complex systems such as NASA s Constellation program which incorporates program, systems and element components that impact others (International Space Station, public, International Partners, etc.). An appropriate IHA should identify all hazards, causes, controls and verifications used to mitigate the risk of catastrophic loss of crew, vehicle and/or mission. Unfortunately, in the current age of increased technology dependence, there is the tendency to sometimes overlook the necessary and sufficient qualifications of the integrator, that is, the person/team that identifies the parts, analyzes the architectural structure, aligns the analysis with the program plan and then communicates/coordinates with large and small components, each contributing necessary hardware, software and/or information to prevent catastrophic loss. As viewed from both Challenger and Columbia accidents, lack of appropriate communication, management errors and lack of resources dedicated to safety were cited as major contributors to these fatalities. From the accident reports, it would appear that the organizational impact of managers, integrators and safety personnel contributes more significantly to mission success and mission failure than purely technological components. If this is so, then organizations who sincerely desire mission success must put as much effort in selecting managers and integrators as they do when designing the hardware, writing the software code and analyzing competitive proposals. This paper will discuss the necessary and sufficient requirements of one of the significant contributors to mission success, the IHA integrator. Discussions will be provided to describe both the mindset required as well as deleterious assumptions/behaviors to avoid when integrating within a large scale system.

Preparation of Nucleic Acid Libraries for Personalized Sequencing Systems Using an Integrated Microfluidic Hub Technology (Seventh Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting 2012)

ScienceCinema

Patel, Kamlesh D.

2018-01-22

Kamlesh (Ken) Patel from Sandia National Laboratories (Livermore, California) presents "Preparation of Nucleic Acid Libraries for Personalized Sequencing Systems Using an Integrated Microfluidic Hub Technology " at the 7th Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting held in June, 2012 in Santa Fe, NM.

Preparation of Nucleic Acid Libraries for Personalized Sequencing Systems Using an Integrated Microfluidic Hub Technology (Seventh Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting 2012)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Patel, Kamlesh D.

2012-06-01

Kamlesh (Ken) Patel from Sandia National Laboratories (Livermore, California) presents "Preparation of Nucleic Acid Libraries for Personalized Sequencing Systems Using an Integrated Microfluidic Hub Technology " at the 7th Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting held in June, 2012 in Santa Fe, NM.

Scramjet nozzle design and analysis as applied to a highly integrated hypersonic research airplane

NASA Technical Reports Server (NTRS)

Small, W. J.; Weidner, J. P.; Johnston, P. J.

1976-01-01

Engine-nozzle airframe integration at hypersonic speeds was conducted by using a high-speed research aircraft concept as a focus. Recently developed techniques for analysis of scramjet-nozzle exhaust flows provide a realistic analysis of complex forces resulting from the engine-nozzle airframe coupling. By properly integrating the engine-nozzle propulsive system with the airframe, efficient, controlled and stable flight results over a wide speed range.

System safety in Stirling engine development

NASA Technical Reports Server (NTRS)

Bankaitis, H.

1981-01-01

The DOE/NASA Stirling Engine Project Office has required that contractors make safety considerations an integral part of all phases of the Stirling engine development program. As an integral part of each engine design subtask, analyses are evolved to determine possible modes of failure. The accepted system safety analysis techniques (Fault Tree, FMEA, Hazards Analysis, etc.) are applied in various degrees of extent at the system, subsystem and component levels. The primary objectives are to identify critical failure areas, to enable removal of susceptibility to such failures or their effects from the system and to minimize risk.

Data Requirement (DR) MA-03: Payload missions integration. [Spacelab payloads

NASA Technical Reports Server (NTRS)

1985-01-01

Project management and payload integration requirements definition activities are reported. Mission peculiar equipment; systems integration; ground operations analysis and requirement definition; safety and quality assurance; and support systems development are examined for payloads planned for the following missions: EOM-1; SL-2; Sl-3 Astro-1; MSL-2; EASE/ACCESS; MPESS; and the middeck ADSF flight.

Ceramic Integration Technologies for Energy and Aerospace Applications

NASA Technical Reports Server (NTRS)

Singh, Mrityunjay; Asthana, Ralph N.

2007-01-01

Robust and affordable integration technologies for advanced ceramics are required to improve the performance, reliability, efficiency, and durability of components, devices, and systems based on them in a wide variety of energy, aerospace, and environmental applications. Many thermochemical and thermomechanical factors including joint design, analysis, and optimization must be considered in integration of similar and dissimilar material systems.

Systems Proteomics for Translational Network Medicine

PubMed Central

Arrell, D. Kent; Terzic, Andre

2012-01-01

Universal principles underlying network science, and their ever-increasing applications in biomedicine, underscore the unprecedented capacity of systems biology based strategies to synthesize and resolve massive high throughput generated datasets. Enabling previously unattainable comprehension of biological complexity, systems approaches have accelerated progress in elucidating disease prediction, progression, and outcome. Applied to the spectrum of states spanning health and disease, network proteomics establishes a collation, integration, and prioritization algorithm to guide mapping and decoding of proteome landscapes from large-scale raw data. Providing unparalleled deconvolution of protein lists into global interactomes, integrative systems proteomics enables objective, multi-modal interpretation at molecular, pathway, and network scales, merging individual molecular components, their plurality of interactions, and functional contributions for systems comprehension. As such, network systems approaches are increasingly exploited for objective interpretation of cardiovascular proteomics studies. Here, we highlight network systems proteomic analysis pipelines for integration and biological interpretation through protein cartography, ontological categorization, pathway and functional enrichment and complex network analysis. PMID:22896016

Integration of passive driver-assistance systems with on-board vehicle systems

NASA Astrophysics Data System (ADS)

Savchenko, V. V.; Poddubko, S. N.

2018-02-01

Implementation in OIAS such functions as driver’s state monitoring and high-precision calculation of the current navigation coordinates of the vehicle, modularity of the OIAS construction and the possible increase in the functionality through integration with other onboard systems has a promising development future. The development of intelligent transport systems and their components allows setting and solving fundamentally new tasks for the safety of human-to-machine transport systems, and the automatic analysis of heterogeneous information flows provides a synergistic effect. The analysis of cross-modal information exchange in human-machine transport systems, from uniform methodological points of view, will allow us, with an accuracy acceptable for solving applied problems, to form in real time an integrated assessment of the state of the basic components of the human-to-machine system and the dynamics in changing situation-centered environment, including the external environment, in their interrelations.

Process and information integration via hypermedia

NASA Technical Reports Server (NTRS)

Hammen, David G.; Labasse, Daniel L.; Myers, Robert M.

1990-01-01

Success stories for advanced automation prototypes abound in the literature but the deployments of practical large systems are few in number. There are several factors that militate against the maturation of such prototypes into products. Here, the integration of advanced automation software into large systems is discussed. Advanced automation systems tend to be specific applications that need to be integrated and aggregated into larger systems. Systems integration can be achieved by providing expert user-developers with verified tools to efficiently create small systems that interface to large systems through standard interfaces. The use of hypermedia as such a tool in the context of the ground control centers that support Shuttle and space station operations is explored. Hypermedia can be an integrating platform for data, conventional software, and advanced automation software, enabling data integration through the display of diverse types of information and through the creation of associative links between chunks of information. Further, hypermedia enables process integration through graphical invoking of system functions. Through analysis and examples, researchers illustrate how diverse information and processing paradigms can be integrated into a single software platform.

An Integrated Library System from Existing Microcomputer Programs.

ERIC Educational Resources Information Center

Kuntz, Lynda S.

1988-01-01

Demonstrates how three commercial microcomputer software packages--PC-Talk III, Wordstar, and dBase III--were combined to produce an integrated library system at the U.S. Army Concepts Analysis Agency library. The retrospective conversion process is discussed, and the four modules of the system are described: acquisitions/cataloging; online…

Analysis of integrated healthcare networks' performance: a contingency-strategic management perspective.

PubMed

Lin, B Y; Wan, T T

1999-12-01

Few empirical analyses have been done in the organizational researches of integrated healthcare networks (IHNs) or integrated healthcare delivery systems. Using a contingency derived contact-process-performance model, this study attempts to explore the relationships among an IHN's strategic direction, structural design, and performance. A cross-sectional analysis of 100 IHNs suggests that certain contextual factors such as market competition and network age and tax status have statistically significant effects on the implementation of an IHN's service differentiation strategy, which addresses coordination and control in the market. An IHN's service differentiation strategy is positively related to its integrated structural design, which is characterized as integration of administration, patient care, and information system across different settings. However, no evidence supports that the development of integrated structural design may benefit an IHN's performance in terms of clinical efficiency and financial viability.

NASA System-Level Design, Analysis and Simulation Tools Research on NextGen

NASA Technical Reports Server (NTRS)

Bardina, Jorge

2011-01-01

A review of the research accomplished in 2009 in the System-Level Design, Analysis and Simulation Tools (SLDAST) of the NASA's Airspace Systems Program is presented. This research thrust focuses on the integrated system-level assessment of component level innovations, concepts and technologies of the Next Generation Air Traffic System (NextGen) under research in the ASP program to enable the development of revolutionary improvements and modernization of the National Airspace System. The review includes the accomplishments on baseline research and the advancements on design studies and system-level assessment, including the cluster analysis as an annualization standard of the air traffic in the U.S. National Airspace, and the ACES-Air MIDAS integration for human-in-the-loop analyzes within the NAS air traffic simulation.

Ten years of maintaining and expanding a microbial genome and metagenome analysis system.

PubMed

Markowitz, Victor M; Chen, I-Min A; Chu, Ken; Pati, Amrita; Ivanova, Natalia N; Kyrpides, Nikos C

2015-11-01

Launched in March 2005, the Integrated Microbial Genomes (IMG) system is a comprehensive data management system that supports multidimensional comparative analysis of genomic data. At the core of the IMG system is a data warehouse that contains genome and metagenome datasets sequenced at the Joint Genome Institute or provided by scientific users, as well as public genome datasets available at the National Center for Biotechnology Information Genbank sequence data archive. Genomes and metagenome datasets are processed using IMG's microbial genome and metagenome sequence data processing pipelines and are integrated into the data warehouse using IMG's data integration toolkits. Microbial genome and metagenome application specific data marts and user interfaces provide access to different subsets of IMG's data and analysis toolkits. This review article revisits IMG's original aims, highlights key milestones reached by the system during the past 10 years, and discusses the main challenges faced by a rapidly expanding system, in particular the complexity of maintaining such a system in an academic setting with limited budgets and computing and data management infrastructure. Copyright © 2015 Elsevier Ltd. All rights reserved.

SUSTAIN:Urban Modeling Systems Integrating Optimization and Economics

EPA Science Inventory

The System for Urban Stormwater Treatment and Analysis INtegration (SUSTAIN) was developed by the U.S. Environmental Protection Agency to support practitioners in developing cost-effective management plans for municipal storm water programs and evaluating and selecting Best Manag...

1992 NASA Life Support Systems Analysis workshop

NASA Technical Reports Server (NTRS)

Evanich, Peggy L.; Crabb, Thomas M.; Gartrell, Charles F.

1992-01-01

The 1992 Life Support Systems Analysis Workshop was sponsored by NASA's Office of Aeronautics and Space Technology (OAST) to integrate the inputs from, disseminate information to, and foster communication among NASA, industry, and academic specialists. The workshop continued discussion and definition of key issues identified in the 1991 workshop, including: (1) modeling and experimental validation; (2) definition of systems analysis evaluation criteria; (3) integration of modeling at multiple levels; and (4) assessment of process control modeling approaches. Through both the 1991 and 1992 workshops, NASA has continued to seek input from industry and university chemical process modeling and analysis experts, and to introduce and apply new systems analysis approaches to life support systems. The workshop included technical presentations, discussions, and interactive planning, with sufficient time allocated for discussion of both technology status and technology development recommendations. Key personnel currently involved with life support technology developments from NASA, industry, and academia provided input to the status and priorities of current and future systems analysis methods and requirements.

Integrated assessment of urban drainage system under the framework of uncertainty analysis.

PubMed

Dong, X; Chen, J; Zeng, S; Zhao, D

2008-01-01

Due to a rapid urbanization as well as the presence of large number of aging urban infrastructures in China, the urban drainage system is facing a dual pressure of construction and renovation nationwide. This leads to the need for an integrated assessment when an urban drainage system is under planning or re-design. In this paper, an integrated assessment methodology is proposed based upon the approaches of analytic hierarchy process (AHP), uncertainty analysis, mathematical simulation of urban drainage system and fuzzy assessment. To illustrate this methodology, a case study in Shenzhen City of south China has been implemented to evaluate and compare two different urban drainage system renovation plans, i.e., the distributed plan and the centralized plan. By comparing their water quality impacts, ecological impacts, technological feasibility and economic costs, the integrated performance of the distributed plan is found to be both better and robust. The proposed methodology is also found to be both effective and practical. (c) IWA Publishing 2008.

Application of a high-energy-density permanent magnet material in underwater systems

NASA Astrophysics Data System (ADS)

Cho, C. P.; Egan, C.; Krol, W. P.

1996-06-01

This paper addresses the application of high-energy-density permanent magnet (PM) technology to (1) the brushless, axial-field PM motor and (2) the integrated electric motor/pump system for under-water applications. Finite-element analysis and lumped parameter magnetic circuit analysis were used to calculate motor parameters and performance characteristics and to conduct tradeoff studies. Compact, efficient, reliable, and quiet underwater systems are attainable with the development of high-energy-density PM material, power electronic devices, and power integrated-circuit technology.

Debris/ice/tps Assessment and Integrated Photographic Analysis of Shuttle Mission STS-81

NASA Technical Reports Server (NTRS)

Katnik, Gregory N.; Lin, Jill D.

1997-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for Shuttle mission STS-81. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the External Tank were assessed by the use of computer programs and infrared scanned data during cryogenic loading of the vehicle, followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or in-flight anomalies. This report documents the ice/debris/thermal protection system conditions and integrated photographic analysis of Shuttle mission STS-81 and the resulting effect on the Space Shuttle Program.

Debris/ice/tps Assessment and Integrated Photographic Analysis of Shuttle Mission STS-83

NASA Technical Reports Server (NTRS)

Lin, Jill D.; Katnik, Gregory N.

1997-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for Shuttle mission STS-83. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the External Tank were assessed by the use of computer programs and infrared scanned data during cryogenic loading of the vehicle, followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or in-flight anomalies. This report documents the ice/debris/thermal protection system conditions and integrated photographic analysis of Shuttle mission STS-83 and the resulting effect on the Space Shuttle Program.

Debris/ice/TPS assessment and integrated photographic analysis of Shuttle Mission STS-71

NASA Technical Reports Server (NTRS)

Katnik, Gregory N.; Bowen, Barry C.; Davis, J. Bradley

1995-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for Shuttle mission STS-71. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the External Tank were assessed by the use of computer programs and infrared scanner data during cryogenic loading of the vehicle, followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or in flight anomalies. This report documents the ice/debris/thermal protection system conditions and integrated photographic analysis of Shuttle mission STS-71 and the resulting effect on the Space Shuttle Program.

Debris/Ice/TPS Assessment and Integrated Photographic Analysis of Shuttle Mission STS-102

NASA Technical Reports Server (NTRS)

Rivera, Jorge E.; Kelly, J. David (Technical Monitor)

2001-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for Shuttle mission STS-102. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the External Tank were assessed by the use of computer programs and infrared scanned data during cryogenic loading of the vehicle, followed by on-pad visual inspection. High speed photography of the launch were analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or inflight anomalies. This report documents the debris/ice /thermal protection system conditions and integrated photographic analysis of Space Shuttle mission STS-102 and the resulting effect on the Space Shuttle Program.

Debris/Ice/TPS Assessment and Integrated Photographic Analysis of Shuttle Mission STS-94

NASA Technical Reports Server (NTRS)

Bowen, Barry C.; Lin, Jill D.

1997-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for Shuttle mission STS-94. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the External Tank were assessed by the use of computer programs and infrared scanned data during cryogenic loading of the vehicle, followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or in-flight anomalies. This report documents the ice/debris/thermal protection system conditions and integrated photographic analysis of Shuttle mission STS-94 and the resulting effect on the Space Shuttle Program.

Debris/ice/tps Assessment and Integrated Photographic Analysis of Shuttle Mission STS-79

NASA Technical Reports Server (NTRS)

Katnik, Gregory N.; Lin, Jill D.

1996-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for Shuttle mission STS-79. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the External Tank were assessed by the use of computer programs and infrared scanned data during cryogenic loading of the vehicle, followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or in-flight anomalies. This report documents the ice/debris/thermal protection system conditions and integrated photographic analysis of Shuttle mission STS-79 and the resulting effect on the Space Shuttle Program.

Debris/ice/TPS assessment and integrated photographic analysis of Shuttle mission STS-73

NASA Technical Reports Server (NTRS)

Katnik, Gregory N.; Bowen, Barry C.; Lin, Jill D.

1995-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for Shuttle mission STS-73. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the External Tank were assessed by the use of computer programs and infrared scanner data during cryogenic loading of the vehicle, followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or in flight anomalies. This report documents the ice/debris/thermal protection system conditions and integrated photographic analysis of Shuttle Mission STS-73 and the resulting effect on the Space Shuttle Program.

Debris/Ice/TPS assessment and integrated photographic analysis of Shuttle Mission STS-77

NASA Technical Reports Server (NTRS)

Katnik, GregoryN.; Lin, Jill D. (Compiler)

1996-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for Shuttle mission STS-77. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the External Tank were assessed by the use of computer programs and infrared scanned data during cryogenic loading of the vehicle, followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or in-flight anomalies. This report documents the ice/debris/thermal protection system conditions and integrated photographic analysis of Shuttle mission STS-77 and the resulting effect on the Space Shuttle Program.

Debris/ice/TPS assessment and integrated photographic analysis of Shuttle Mission STS-70

NASA Technical Reports Server (NTRS)

Katnik, Gregory N.; Bowen, Barry C.; Davis, J. Bradley

1995-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for Shuttle mission STS-70. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the External Tank were assessed by the use of computer programs and infrared scanner data during cryogenic loading of the vehicle, followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or in flight anomalies. This report documents the ice/debris/thermal protection system conditions and integrated photographic analysis of Shuttle mission STS-70 and the resulting effect on the Space Shuttle Program.

Debris/ice/TPS assessment and integrated photographic analysis of Shuttle mission STS-69

NASA Technical Reports Server (NTRS)

Katnik, Gregory N.; Bowen, Barry C.; Davis, J. Bradley

1995-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for Shuttle mission STS-69. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the External Tank were assessed by the use of computer programs and infrared scanner data during cryogenic loading of the vehicle, followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or in flight anomalies. This report documents the ice/debris/thermal protection system condition and integrated photographic analysis of Shuttle Mission STS-69 and the resulting effect on the Space Shuttle Program.

Debris/Ice/TPS Assessment and Integrated Photographic Analysis of Shuttle Mission STS-106

NASA Technical Reports Server (NTRS)

Katnik, Gregory N.; Kelley, J. David (Technical Monitor)

2000-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for Shuttle mission STS-106. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the External Tank were assessed by the use of computer programs and infrared scanned data during cryogenic loading of the vehicle followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and in-flight anomalies. This report documents the ice/debris/thermal protection system conditions and integrated photographic analysis of Space Shuttle mission STS-106 and the resulting effect on the Space Shuttle Program.

Debris/Ice/TPS assessment and integrated photographic analysis of shuttle mission STS-76

NASA Technical Reports Server (NTRS)

Lin, Jill D.

1996-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for Shuttle mission STS-76. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the External Tank were assessed by the use of computer programs and infrared scanned data during cryogenic loading of the vehicle, followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or in-flight anomalies. This report documents the ice/debris/thermal protection system conditions and integrated photographic analysis of Shuttle mission STS-76 and the resulting effect on the Space Shuttle Program.

Debris/Ice/TPS Assessment and Integrated Photographic Analysis of Shuttle Mission STS-72

NASA Technical Reports Server (NTRS)

Katnik, Gregory N.; Bowen, Barry C.; Lin, Jill D.

1996-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for Shuttle mission STS-72. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the External Tank were assessed by the use of computer programs and infrared scanned data during cryogenic loading of the vehicle, followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or in-flight anomalies. This report documents the ice/debris/thermal protection system conditions and integrated photographic analysis of Shuttle mission STS-72 and the resulting effect on the Space Shuttle Program.

Reducing the Risk of Human Space Missions with INTEGRITY

NASA Technical Reports Server (NTRS)

Jones, Harry W.; Dillon-Merill, Robin L.; Tri, Terry O.; Henninger, Donald L.

2003-01-01

The INTEGRITY Program will design and operate a test bed facility to help prepare for future beyond-LEO missions. The purpose of INTEGRITY is to enable future missions by developing, testing, and demonstrating advanced human space systems. INTEGRITY will also implement and validate advanced management techniques including risk analysis and mitigation. One important way INTEGRITY will help enable future missions is by reducing their risk. A risk analysis of human space missions is important in defining the steps that INTEGRITY should take to mitigate risk. This paper describes how a Probabilistic Risk Assessment (PRA) of human space missions will help support the planning and development of INTEGRITY to maximize its benefits to future missions. PRA is a systematic methodology to decompose the system into subsystems and components, to quantify the failure risk as a function of the design elements and their corresponding probability of failure. PRA provides a quantitative estimate of the probability of failure of the system, including an assessment and display of the degree of uncertainty surrounding the probability. PRA provides a basis for understanding the impacts of decisions that affect safety, reliability, performance, and cost. Risks with both high probability and high impact are identified as top priority. The PRA of human missions beyond Earth orbit will help indicate how the risk of future human space missions can be reduced by integrating and testing systems in INTEGRITY.

Preliminary candidate advanced avionics system for general aviation

NASA Technical Reports Server (NTRS)

Mccalla, T. M.; Grismore, F. L.; Greatline, S. E.; Birkhead, L. M.

1977-01-01

An integrated avionics system design was carried out to the level which indicates subsystem function, and the methods of overall system integration. Sufficient detail was included to allow identification of possible system component technologies, and to perform reliability, modularity, maintainability, cost, and risk analysis upon the system design. Retrofit to older aircraft, availability of this system to the single engine two place aircraft, was considered.

ARC Research Areas and Projects

Science.gov Websites

support ground vehicle system-of-systems integration. This integration may involve not just a vehicle but also the humans inside and the support systems outside, as well as a wide variety of missions with issues pertaining to design, analysis and optimization of ground vehicle systems. Work is organized in

System integration of marketable subsystems

NASA Technical Reports Server (NTRS)

1978-01-01

These monthly reports, covering the period February 1978 through June 1978, describe the progress made in the major areas of the program. The areas covered are: systems integration of marketable subsystems; development, design, and building of site data acquisition subsystems; development and operation of the central data processing system; operation of the MSFC Solar Test Facility; and systems analysis.

An integrated GIS application system for soil moisture data assimilation

NASA Astrophysics Data System (ADS)

Wang, Di; Shen, Runping; Huang, Xiaolong; Shi, Chunxiang

2014-11-01

The gaps in knowledge and existing challenges in precisely describing the land surface process make it critical to represent the massive soil moisture data visually and mine the data for further research.This article introduces a comprehensive soil moisture assimilation data analysis system, which is instructed by tools of C#, IDL, ArcSDE, Visual Studio 2008 and SQL Server 2005. The system provides integrated service, management of efficient graphics visualization and analysis of land surface data assimilation. The system is not only able to improve the efficiency of data assimilation management, but also comprehensively integrate the data processing and analysis tools into GIS development environment. So analyzing the soil moisture assimilation data and accomplishing GIS spatial analysis can be realized in the same system. This system provides basic GIS map functions, massive data process and soil moisture products analysis etc. Besides,it takes full advantage of a spatial data engine called ArcSDE to effeciently manage, retrieve and store all kinds of data. In the system, characteristics of temporal and spatial pattern of soil moiture will be plotted. By analyzing the soil moisture impact factors, it is possible to acquire the correlation coefficients between soil moisture value and its every single impact factor. Daily and monthly comparative analysis of soil moisture products among observations, simulation results and assimilations can be made in this system to display the different trends of these products. Furthermore, soil moisture map production function is realized for business application.

Energy Analysis Publications | Energy Analysis | NREL

Science.gov Websites

Systems Impact Analysis We perform impact analysis to evaluate and understand the impact of markets publications. Featured Publications Complex Systems Analysis Complex systems analysis integrates all aspects of , policies, and financing on technology uptake and the impact of new technologies on markets and policy

Supporting community annotation and user collaboration in the integrated microbial genomes (IMG) system.

PubMed

Chen, I-Min A; Markowitz, Victor M; Palaniappan, Krishna; Szeto, Ernest; Chu, Ken; Huang, Jinghua; Ratner, Anna; Pillay, Manoj; Hadjithomas, Michalis; Huntemann, Marcel; Mikhailova, Natalia; Ovchinnikova, Galina; Ivanova, Natalia N; Kyrpides, Nikos C

2016-04-26

The exponential growth of genomic data from next generation technologies renders traditional manual expert curation effort unsustainable. Many genomic systems have included community annotation tools to address the problem. Most of these systems adopted a "Wiki-based" approach to take advantage of existing wiki technologies, but encountered obstacles in issues such as usability, authorship recognition, information reliability and incentive for community participation. Here, we present a different approach, relying on tightly integrated method rather than "Wiki-based" method, to support community annotation and user collaboration in the Integrated Microbial Genomes (IMG) system. The IMG approach allows users to use existing IMG data warehouse and analysis tools to add gene, pathway and biosynthetic cluster annotations, to analyze/reorganize contigs, genes and functions using workspace datasets, and to share private user annotations and workspace datasets with collaborators. We show that the annotation effort using IMG can be part of the research process to overcome the user incentive and authorship recognition problems thus fostering collaboration among domain experts. The usability and reliability issues are addressed by the integration of curated information and analysis tools in IMG, together with DOE Joint Genome Institute (JGI) expert review. By incorporating annotation operations into IMG, we provide an integrated environment for users to perform deeper and extended data analysis and annotation in a single system that can lead to publications and community knowledge sharing as shown in the case studies.

Development of Integrated Flood Analysis System for Improving Flood Mitigation Capabilities in Korea

NASA Astrophysics Data System (ADS)

Moon, Young-Il; Kim, Jong-suk

2016-04-01

Recently, the needs of people are growing for a more safety life and secure homeland from unexpected natural disasters. Flood damages have been recorded every year and those damages are greater than the annual average of 2 trillion won since 2000 in Korea. It has been increased in casualties and property damages due to flooding caused by hydrometeorlogical extremes according to climate change. Although the importance of flooding situation is emerging rapidly, studies related to development of integrated management system for reducing floods are insufficient in Korea. In addition, it is difficult to effectively reduce floods without developing integrated operation system taking into account of sewage pipe network configuration with the river level. Since the floods result in increasing damages to infrastructure, as well as life and property, structural and non-structural measures should be urgently established in order to effectively reduce the flood. Therefore, in this study, we developed an integrated flood analysis system that systematized technology to quantify flood risk and flood forecasting for supporting synthetic decision-making through real-time monitoring and prediction on flash rain or short-term rainfall by using radar and satellite information in Korea. Keywords: Flooding, Integrated flood analysis system, Rainfall forecasting, Korea Acknowledgments This work was carried out with the support of "Cooperative Research Program for Agriculture Science & Technology Development (Project No. PJ011686022015)" Rural Development Administration, Republic of Korea

Cantera Integration with the Toolbox for Modeling and Analysis of Thermodynamic Systems (T-MATS)

NASA Technical Reports Server (NTRS)

Lavelle, Thomas M.; Chapman, Jeffryes W.; May, Ryan D.; Litt, Jonathan S.; Guo, Ten-Huei

2014-01-01

NASA Glenn Research Center (GRC) has recently developed a software package for modeling generic thermodynamic systems called the Toolbox for the Modeling and Analysis of Thermodynamic Systems (T-MATS). T-MATS is a library of building blocks that can be assembled to represent any thermodynamic system in the Simulink(Registered TradeMark) (The MathWorks, Inc.) environment. These elements, along with a Newton Raphson solver (also provided as part of the T-MATS package), enable users to create models of a wide variety of systems. The current version of T-MATS (v1.0.1) uses tabular data for providing information about a specific mixture of air, water (humidity), and hydrocarbon fuel in calculations of thermodynamic properties. The capabilities of T-MATS can be expanded by integrating it with the Cantera thermodynamic package. Cantera is an object-oriented analysis package that calculates thermodynamic solutions for any mixture defined by the user. Integration of Cantera with T-MATS extends the range of systems that may be modeled using the toolbox. In addition, the library of elements released with Cantera were developed using MATLAB native M-files, allowing for quicker prototyping of elements. This paper discusses how the new Cantera-based elements are created and provides examples for using T-MATS integrated with Cantera.

Cantera Integration with the Toolbox for Modeling and Analysis of Thermodynamic Systems (T-MATS)

NASA Technical Reports Server (NTRS)

Lavelle, Thomas M.; Chapman, Jeffryes W.; May, Ryan D.; Litt, Jonathan S.; Guo, Ten-Huei

2014-01-01

NASA Glenn Research Center (GRC) has recently developed a software package for modeling generic thermodynamic systems called the Toolbox for the Modeling and Analysis of Thermodynamic Systems (T-MATS). T-MATS is a library of building blocks that can be assembled to represent any thermodynamic system in the Simulink (The MathWorks, Inc.) environment. These elements, along with a Newton Raphson solver (also provided as part of the T-MATS package), enable users to create models of a wide variety of systems. The current version of T-MATS (v1.0.1) uses tabular data for providing information about a specific mixture of air, water (humidity), and hydrocarbon fuel in calculations of thermodynamic properties. The capabilities of T-MATS can be expanded by integrating it with the Cantera thermodynamic package. Cantera is an object-oriented analysis package that calculates thermodynamic solutions for any mixture defined by the user. Integration of Cantera with T-MATS extends the range of systems that may be modeled using the toolbox. In addition, the library of elements released with Cantera were developed using MATLAB native M-files, allowing for quicker prototyping of elements. This paper discusses how the new Cantera-based elements are created and provides examples for using T-MATS integrated with Cantera.

Systematic analysis of signaling pathways using an integrative environment.

PubMed

Visvanathan, Mahesh; Breit, Marc; Pfeifer, Bernhard; Baumgartner, Christian; Modre-Osprian, Robert; Tilg, Bernhard

2007-01-01

Understanding the biological processes of signaling pathways as a whole system requires an integrative software environment that has comprehensive capabilities. The environment should include tools for pathway design, visualization, simulation and a knowledge base concerning signaling pathways as one. In this paper we introduce a new integrative environment for the systematic analysis of signaling pathways. This system includes environments for pathway design, visualization, simulation and a knowledge base that combines biological and modeling information concerning signaling pathways that provides the basic understanding of the biological system, its structure and functioning. The system is designed with a client-server architecture. It contains a pathway designing environment and a simulation environment as upper layers with a relational knowledge base as the underlying layer. The TNFa-mediated NF-kB signal trans-duction pathway model was designed and tested using our integrative framework. It was also useful to define the structure of the knowledge base. Sensitivity analysis of this specific pathway was performed providing simulation data. Then the model was extended showing promising initial results. The proposed system offers a holistic view of pathways containing biological and modeling data. It will help us to perform biological interpretation of the simulation results and thus contribute to a better understanding of the biological system for drug identification.

Integrated energy balance analysis for Space Station Freedom

NASA Technical Reports Server (NTRS)

Tandler, John

1991-01-01

An integrated simulation model is described which characterizes the dynamic interaction of the energy transport subsystems of Space Station Freedom for given orbital conditions and for a given set of power and thermal loads. Subsystems included in the model are the Electric Power System (EPS), the Internal Thermal Control System (ITCS), the External Thermal Control System (ETCS), and the cabin Temperature and Humidity Control System (THC) (which includes the avionics air cooling, cabin air cooling, and intermodule ventilation systems). Models of the subsystems were developed in a number of system-specific modeling tools and validated. The subsystem models are then combined into integrated models to address a number of integrated performance issues involving the ability of the integrated energy transport system of Space Station Freedom to provide power, controlled cabin temperature and humidity, and equipment thermal control to support operations.

Advancing Globally Integrated Logistics Effort 2017 Wargame Report

DTIC Science & Technology

2017-09-01

September 2017 Dr. M. Webster Ewell, Jr. Director, Integration and Gaming Team Advanced Technology and Systems Analysis REPORT...release: distribution unlimited. 13. SUPPLEMENTARY NOTES 14. ABSTRACT This report describes the execution and analysis of a logistics game created for...the Joint Staff J-4, Directorate for Logistics. The game , Advancing Globally Integrated Logistics Effort 2017 (AGILE 17), centered on developing a

Distributed software framework and continuous integration in hydroinformatics systems

NASA Astrophysics Data System (ADS)

Zhou, Jianzhong; Zhang, Wei; Xie, Mengfei; Lu, Chengwei; Chen, Xiao

2017-08-01

When encountering multiple and complicated models, multisource structured and unstructured data, complex requirements analysis, the platform design and integration of hydroinformatics systems become a challenge. To properly solve these problems, we describe a distributed software framework and it’s continuous integration process in hydroinformatics systems. This distributed framework mainly consists of server cluster for models, distributed database, GIS (Geographic Information System) servers, master node and clients. Based on it, a GIS - based decision support system for joint regulating of water quantity and water quality of group lakes in Wuhan China is established.

Optical design and tolerancing of an ophthalmological system

NASA Astrophysics Data System (ADS)

Sieber, Ingo; Martin, Thomas; Yi, Allen; Li, Likai; Rübenach, Olaf

2014-09-01

Tolerance analysis by means of simulation is an essential step in system integration. Tolerance analysis allows for predicting the performance of a system setup of real manufactured parts and for an estimation of the yield with respect to evaluation figures, such as performance requirements, systems specification or cost demands. Currently, optical freeform optics is gaining importance in optical systems design. The performance of freeform optics often strongly depends on the manufacturing accuracy of the surfaces. For this reason, a tolerance analysis with respect to the fabrication accuracy is of crucial importance. The characterization of form tolerances caused by the manufacturing process is based on the definition of straightness, flatness, roundness, and cylindricity. In case of freeform components, however, it is often impossible to define a form deviation by means of this standard classification. Hence, prediction of the impact of manufacturing tolerances on the optical performance is not possible by means of a conventional tolerance analysis. To carry out a tolerance analysis of the optical subsystem, including freeform optics, metrology data of the fabricated surfaces have to be integrated into the optical model. The focus of this article is on design for manufacturability of freeform optics with integrated alignment structures and on tolerance analysis of the optical subsystem based on the measured surface data of manufactured optical freeform components with respect to assembly and manufacturing tolerances. This approach will be reported here using an ophthalmological system as an example.

Pattern Analysis and Decision Support for Cancer through Clinico-Genomic Profiles

NASA Astrophysics Data System (ADS)

Exarchos, Themis P.; Giannakeas, Nikolaos; Goletsis, Yorgos; Papaloukas, Costas; Fotiadis, Dimitrios I.

Advances in genome technology are playing a growing role in medicine and healthcare. With the development of new technologies and opportunities for large-scale analysis of the genome, genomic data have a clear impact on medicine. Cancer prognostics and therapeutics are among the first major test cases for genomic medicine, given that all types of cancer are related with genomic instability. In this paper we present a novel system for pattern analysis and decision support in cancer. The system integrates clinical data from electronic health records and genomic data. Pattern analysis and data mining methods are applied to these integrated data and the discovered knowledge is used for cancer decision support. Through this integration, conclusions can be drawn for early diagnosis, staging and cancer treatment.

Application of the Tool for Turbine Engine Closed-loop Transient Analysis (TTECTrA) for Dynamic Systems Analysis

NASA Technical Reports Server (NTRS)

Csank, Jeffrey; Zinnecker, Alicia

2014-01-01

Systems analysis involves steady-state simulations of combined components to evaluate the steady-state performance, weight, and cost of a system; dynamic considerations are not included until later in the design process. The Dynamic Systems Analysis task, under NASAs Fixed Wing project, is developing the capability for assessing dynamic issues at earlier stages during systems analysis. To provide this capability the Tool for Turbine Engine Closed-loop Transient Analysis (TTECTrA) has been developed to design a single flight condition controller (defined as altitude and Mach number) and, ultimately, provide an estimate of the closed-loop performance of the engine model. This tool has been integrated with the Commercial Modular Aero-Propulsion System Simulation 40,000(CMAPSS40k) engine model to demonstrate the additional information TTECTrA makes available for dynamic systems analysis. This dynamic data can be used to evaluate the trade-off between performance and safety, which could not be done with steady-state systems analysis data. TTECTrA has been designed to integrate with any turbine engine model that is compatible with the MATLABSimulink (The MathWorks, Inc.) environment.

Application of the Tool for Turbine Engine Closed-loop Transient Analysis (TTECTrA) for Dynamic Systems Analysis

NASA Technical Reports Server (NTRS)

Csank, Jeffrey Thomas; Zinnecker, Alicia Mae

2014-01-01

Systems analysis involves steady-state simulations of combined components to evaluate the steady-state performance, weight, and cost of a system; dynamic considerations are not included until later in the design process. The Dynamic Systems Analysis task, under NASAs Fixed Wing project, is developing the capability for assessing dynamic issues at earlier stages during systems analysis. To provide this capability the Tool for Turbine Engine Closed-loop Transient Analysis (TTECTrA) has been developed to design a single flight condition controller (defined as altitude and Mach number) and, ultimately, provide an estimate of the closed-loop performance of the engine model. This tool has been integrated with the Commercial Modular Aero-Propulsion System Simulation 40,000 (CMAPSS 40k) engine model to demonstrate the additional information TTECTrA makes available for dynamic systems analysis. This dynamic data can be used to evaluate the trade-off between performance and safety, which could not be done with steady-state systems analysis data. TTECTrA has been designed to integrate with any turbine engine model that is compatible with the MATLAB Simulink (The MathWorks, Inc.) environment.

A Synthetic Vision Preliminary Integrated Safety Analysis

NASA Technical Reports Server (NTRS)

Hemm, Robert; Houser, Scott

2001-01-01

This report documents efforts to analyze a sample of aviation safety programs, using the LMI-developed integrated safety analysis tool to determine the change in system risk resulting from Aviation Safety Program (AvSP) technology implementation. Specifically, we have worked to modify existing system safety tools to address the safety impact of synthetic vision (SV) technology. Safety metrics include reliability, availability, and resultant hazard. This analysis of SV technology is intended to be part of a larger effort to develop a model that is capable of "providing further support to the product design and development team as additional information becomes available". The reliability analysis portion of the effort is complete and is fully documented in this report. The simulation analysis is still underway; it will be documented in a subsequent report. The specific goal of this effort is to apply the integrated safety analysis to SV technology. This report also contains a brief discussion of data necessary to expand the human performance capability of the model, as well as a discussion of human behavior and its implications for system risk assessment in this modeling environment.

Integrated tools for control-system analysis

NASA Technical Reports Server (NTRS)

Ostroff, Aaron J.; Proffitt, Melissa S.; Clark, David R.

1989-01-01

The basic functions embedded within a user friendly software package (MATRIXx) are used to provide a high level systems approach to the analysis of linear control systems. Various control system analysis configurations are assembled automatically to minimize the amount of work by the user. Interactive decision making is incorporated via menu options and at selected points, such as in the plotting section, by inputting data. There are five evaluations such as the singular value robustness test, singular value loop transfer frequency response, Bode frequency response, steady-state covariance analysis, and closed-loop eigenvalues. Another section describes time response simulations. A time response for random white noise disturbance is available. The configurations and key equations used for each type of analysis, the restrictions that apply, the type of data required, and an example problem are described. One approach for integrating the design and analysis tools is also presented.

Long-Term Preservation and Advanced Access Services to Archived Data: The Approach of a System Integrator

NASA Astrophysics Data System (ADS)

Petitjean, Gilles; de Hauteclocque, Bertrand

2004-06-01

EADS Defence and Security Systems (EADS DS SA) have developed an expertise as integrator of archive management systems for both their commercial and defence customers (ESA, CNES, EC, EUMETSAT, French MOD, US DOD, etc.), especially in Earth Observation and in Meteorology fields.The concern of valuable data owners is both their long-term preservation but also the integration of the archive in their information system with in particular an efficient access to archived data for their user community. The system integrator answers to this requirement by a methodology combining understanding of user needs, exhaustive knowledge of the existing solutions both for hardware and software elements and development and integration ability. The system integrator completes the facility development by support activities.The long-term preservation of archived data obviously involves a pertinent selection of storage media and archive library. This selection relies on storage technology survey but the selection criteria depend on the analysis of the user needs. The system integrator will recommend the best compromise for implementing an archive management facility, thanks to its knowledge and its independence of storage market and through the analysis of the user requirements. He will provide a solution, which is able to evolve to take advantage of the storage technology progress.But preserving the data for long-term is not only a question of storage technology. Some functions are required to secure the archive management system against contingency situation: multiple data set copies using operational procedures, active quality control of the archived data, migration policy optimising the cost of ownership.

Overview of the systems special investigation. [long duration exposure facility

NASA Technical Reports Server (NTRS)

Mason, James B.; Dursch, Harry; Edelman, Joel

1992-01-01

The Systems Special Investigation Group (SIG), formed by the Long Duration Exposure Facility (LDEF) Project Office to perform post flight analysis of systems hardware, was chartered to investigate the effects of the extended LDEF mission on both satellite and experiment systems and to coordinate and integrate all systems analysis performed in post flight investigations. Almost all of the top level functional testing of the active experiments has been completed, but many components are still under investigation by either the Systems SIG or individual experimenters. Results reported to date have been collected and integrated by the Systems SIG and an overview of the current results and the status of the Systems Investigation are presented in this paper.

Design for perception management system on offshore reef based on integrated management

NASA Astrophysics Data System (ADS)

Peng, Li; Qiankun, Wang

2017-06-01

According to an analysis of actual monitoring demands using integrated management and information technology, a quad monitoring system is proposed to provide intelligent perception of offshore reefs, including indoor building environments, architectural structures, and facilities and perimeter integrity. This will strengthen the ability to analyse and evaluate offshore reef operation and health, promoting efficiency in decision making.

A System for Integrated Reliability and Safety Analyses

NASA Technical Reports Server (NTRS)

Kostiuk, Peter; Shapiro, Gerald; Hanson, Dave; Kolitz, Stephan; Leong, Frank; Rosch, Gene; Coumeri, Marc; Scheidler, Peter, Jr.; Bonesteel, Charles

1999-01-01

We present an integrated reliability and aviation safety analysis tool. The reliability models for selected infrastructure components of the air traffic control system are described. The results of this model are used to evaluate the likelihood of seeing outcomes predicted by simulations with failures injected. We discuss the design of the simulation model, and the user interface to the integrated toolset.

Human factors considerations for the integration of unmanned aerial vehicles in the National Airspace System : an analysis of reports submitted to the Aviation Safety Reporting System (ASRS)

DOT National Transportation Integrated Search

2017-06-06

Successful integration of Unmanned Aerial Vehicle (UAV) operations into the National Airspace System requires the identification and mitigation of operational risks. This report reviews human factors issues that have been identified in operational as...

Human Systems Integration at NASA Ames Research Center

NASA Technical Reports Server (NTRS)

McCandless, Jeffrey

2017-01-01

The Human Systems Integration Division focuses on the design and operations of complex aerospace systems through analysis, experimentation and modeling. With over a dozen labs and over 120 people, the division conducts research to improve safety, efficiency and mission success. Areas of investigation include applied vision research which will be discussed during this seminar.

Pyrosequencing analysis for characterization of bacterial diversity in a soil as affected by integrated livestock-cotton production systems

USDA-ARS?s Scientific Manuscript database

Impacts of integrated livestock-crop production systems compared to specialized systems on soil bacterial diversity have not been well documented. We used a bacterial tag encoded FLX amplicon pyrosequencing (bTEFAP) method to evaluate bacterial diversity of a clay loam soil (Fine, mixed, thermic To...

Combining data from multiple sources using the CUAHSI Hydrologic Information System

NASA Astrophysics Data System (ADS)

Tarboton, D. G.; Ames, D. P.; Horsburgh, J. S.; Goodall, J. L.

2012-12-01

The Consortium of Universities for the Advancement of Hydrologic Science, Inc. (CUAHSI) has developed a Hydrologic Information System (HIS) to provide better access to data by enabling the publication, cataloging, discovery, retrieval, and analysis of hydrologic data using web services. The CUAHSI HIS is an Internet based system comprised of hydrologic databases and servers connected through web services as well as software for data publication, discovery and access. The HIS metadata catalog lists close to 100 web services registered to provide data through this system, ranging from large federal agency data sets to experimental watersheds managed by University investigators. The system's flexibility in storing and enabling public access to similarly formatted data and metadata has created a community data resource from governmental and academic data that might otherwise remain private or analyzed only in isolation. Comprehensive understanding of hydrology requires integration of this information from multiple sources. HydroDesktop is the client application developed as part of HIS to support data discovery and access through this system. HydroDesktop is founded on an open source GIS client and has a plug-in architecture that has enabled the integration of modeling and analysis capability with the functionality for data discovery and access. Model integration is possible through a plug-in built on the OpenMI standard and data visualization and analysis is supported by an R plug-in. This presentation will demonstrate HydroDesktop, showing how it provides an analysis environment within which data from multiple sources can be discovered, accessed and integrated.

KA-SB: from data integration to large scale reasoning

PubMed Central

Roldán-García, María del Mar; Navas-Delgado, Ismael; Kerzazi, Amine; Chniber, Othmane; Molina-Castro, Joaquín; Aldana-Montes, José F

2009-01-01

Background The analysis of information in the biological domain is usually focused on the analysis of data from single on-line data sources. Unfortunately, studying a biological process requires having access to disperse, heterogeneous, autonomous data sources. In this context, an analysis of the information is not possible without the integration of such data. Methods KA-SB is a querying and analysis system for final users based on combining a data integration solution with a reasoner. Thus, the tool has been created with a process divided into two steps: 1) KOMF, the Khaos Ontology-based Mediator Framework, is used to retrieve information from heterogeneous and distributed databases; 2) the integrated information is crystallized in a (persistent and high performance) reasoner (DBOWL). This information could be further analyzed later (by means of querying and reasoning). Results In this paper we present a novel system that combines the use of a mediation system with the reasoning capabilities of a large scale reasoner to provide a way of finding new knowledge and of analyzing the integrated information from different databases, which is retrieved as a set of ontology instances. This tool uses a graphical query interface to build user queries easily, which shows a graphical representation of the ontology and allows users o build queries by clicking on the ontology concepts. Conclusion These kinds of systems (based on KOMF) will provide users with very large amounts of information (interpreted as ontology instances once retrieved), which cannot be managed using traditional main memory-based reasoners. We propose a process for creating persistent and scalable knowledgebases from sets of OWL instances obtained by integrating heterogeneous data sources with KOMF. This process has been applied to develop a demo tool , which uses the BioPax Level 3 ontology as the integration schema, and integrates UNIPROT, KEGG, CHEBI, BRENDA and SABIORK databases. PMID:19796402

Integrated corridor management initiative : demonstration phase evaluation, San Diego decision support system analysis test plan.

DOT National Transportation Integrated Search

2000-01-01

This report demonstrates the benefits and potential pitfalls of deploying and operating an integrated freeway and arterial management system. In particular, it discusses the lessons learned about the Medical Center Corridor (MCC) Project deployed in ...

Out of the Frying Pan into the Fire? A Critical Analysis of the Integrated Children's System

ERIC Educational Resources Information Center

Calder, Martin C.

2004-01-01

Much has been promised from the government about providing a more contemporary and streamlined system for child care at the beginning of the 21st century. In this article Calder critically evaluates the origins of the incoming Integrated Children's System and questions how welding two faulty and discredited systems from the 1990s together can…

NASA/Army Rotorcraft Technology. Volume 3: Systems Integration, Research Aircraft, and Industry

NASA Technical Reports Server (NTRS)

1988-01-01

This is part 3 of the conference proceedings on rotorcraft technology. This volume is divided into areas on systems integration, research aircraft, and industry. Representative titles from each area are: system analysis in rotorcraft design, the past decade; rotorcraft flight research with emphasis on rotor systems; and an overview of key technology thrusts at Bell Helicopter Textron.

Evolving Postmortems as Teams Evolve Through TxP

DTIC Science & Technology

2014-12-01

Instead of waiting for SEI to compile enough data to repeat this kind of analysis for the system integration test domain , a system integration test team...and stand up their Team Test Process (TTP). Some abilities, like planning on how many mistakes will be made by the team in producing a test procedure...can only be performed after the team has determined a) which mistakes count in the domain of system integration testing, b) what units to use to

NASA Systems Engineering Research Consortium: Defining the Path to Elegance in Systems

NASA Technical Reports Server (NTRS)

Watson, Michael D.; Farrington, Phillip A.

2016-01-01

The NASA Systems Engineering Research Consortium was formed at the end of 2010 to study the approaches to producing elegant systems on a consistent basis. This has been a transformative study looking at the engineering and organizational basis of systems engineering. The consortium has engaged in a variety of research topics to determine the path to elegant systems. In the second year of the consortium, a systems engineering framework emerged which structured the approach to systems engineering and guided our research. This led in the third year to set of systems engineering postulates that the consortium is continuing to refine. The consortium has conducted several research projects that have contributed significantly to the understanding of systems engineering. The consortium has surveyed the application of the NASA 17 systems engineering processes, explored the physics and statistics of systems integration, and considered organizational aspects of systems engineering discipline integration. The systems integration methods have included system exergy analysis, Akaike Information Criteria (AIC), State Variable Analysis, Multidisciplinary Coupling Analysis (MCA), Multidisciplinary Design Optimization (MDO), System Cost Modelling, System Robustness, and Value Modelling. Organizational studies have included the variability of processes in change evaluations, margin management within the organization, information theory of board structures, social categorization of unintended consequences, and initial looks at applying cognitive science to systems engineering. Consortium members have also studied the bidirectional influence of policy and law with systems engineering.

NASA Systems Engineering Research Consortium: Defining the Path to Elegance in Systems

NASA Technical Reports Server (NTRS)

Watson, Michael D.; Farrington, Phillip A.

2016-01-01

The NASA Systems Engineering Research Consortium was formed at the end of 2010 to study the approaches to producing elegant systems on a consistent basis. This has been a transformative study looking at the engineering and organizational basis of systems engineering. The consortium has engaged in a variety of research topics to determine the path to elegant systems. In the second year of the consortium, a systems engineering framework emerged which structured the approach to systems engineering and guided our research. This led in the third year to set of systems engineering postulates that the consortium is continuing to refine. The consortium has conducted several research projects that have contributed significantly to the understanding of systems engineering. The consortium has surveyed the application of the NASA 17 systems engineering processes, explored the physics and statistics of systems integration, and considered organizational aspects of systems engineering discipline integration. The systems integration methods have included system energy analysis, Akaike Information Criteria (AIC), State Variable Analysis, Multidisciplinary Coupling Analysis (MCA), Multidisciplinary Design Optimization (MDO), System Cost Modeling, System Robustness, and Value Modeling. Organizational studies have included the variability of processes in change evaluations, margin management within the organization, information theory of board structures, social categorization of unintended consequences, and initial looks at applying cognitive science to systems engineering. Consortium members have also studied the bidirectional influence of policy and law with systems engineering.

An Integrated Tool for System Analysis of Sample Return Vehicles

NASA Technical Reports Server (NTRS)

Samareh, Jamshid A.; Maddock, Robert W.; Winski, Richard G.

2012-01-01

The next important step in space exploration is the return of sample materials from extraterrestrial locations to Earth for analysis. Most mission concepts that return sample material to Earth share one common element: an Earth entry vehicle. The analysis and design of entry vehicles is multidisciplinary in nature, requiring the application of mass sizing, flight mechanics, aerodynamics, aerothermodynamics, thermal analysis, structural analysis, and impact analysis tools. Integration of a multidisciplinary problem is a challenging task; the execution process and data transfer among disciplines should be automated and consistent. This paper describes an integrated analysis tool for the design and sizing of an Earth entry vehicle. The current tool includes the following disciplines: mass sizing, flight mechanics, aerodynamics, aerothermodynamics, and impact analysis tools. Python and Java languages are used for integration. Results are presented and compared with the results from previous studies.

Booly: a new data integration platform.

PubMed

Do, Long H; Esteves, Francisco F; Karten, Harvey J; Bier, Ethan

2010-10-13

Data integration is an escalating problem in bioinformatics. We have developed a web tool and warehousing system, Booly, that features a simple yet flexible data model coupled with the ability to perform powerful comparative analysis, including the use of Boolean logic to merge datasets together, and an integrated aliasing system to decipher differing names of the same gene or protein. Furthermore, Booly features a collaborative sharing system and a public repository so that users can retrieve new datasets while contributors can easily disseminate new content. We illustrate the uses of Booly with several examples including: the versatile creation of homebrew datasets, the integration of heterogeneous data to identify genes useful for comparing avian and mammalian brain architecture, and generation of a list of Food and Drug Administration (FDA) approved drugs with possible alternative disease targets. The Booly paradigm for data storage and analysis should facilitate integration between disparate biological and medical fields and result in novel discoveries that can then be validated experimentally. Booly can be accessed at http://booly.ucsd.edu.

Booly: a new data integration platform

PubMed Central

2010-01-01

Background Data integration is an escalating problem in bioinformatics. We have developed a web tool and warehousing system, Booly, that features a simple yet flexible data model coupled with the ability to perform powerful comparative analysis, including the use of Boolean logic to merge datasets together, and an integrated aliasing system to decipher differing names of the same gene or protein. Furthermore, Booly features a collaborative sharing system and a public repository so that users can retrieve new datasets while contributors can easily disseminate new content. Results We illustrate the uses of Booly with several examples including: the versatile creation of homebrew datasets, the integration of heterogeneous data to identify genes useful for comparing avian and mammalian brain architecture, and generation of a list of Food and Drug Administration (FDA) approved drugs with possible alternative disease targets. Conclusions The Booly paradigm for data storage and analysis should facilitate integration between disparate biological and medical fields and result in novel discoveries that can then be validated experimentally. Booly can be accessed at http://booly.ucsd.edu. PMID:20942966

Multidisciplinary High-Fidelity Analysis and Optimization of Aerospace Vehicles. Part 1; Formulation

NASA Technical Reports Server (NTRS)

Walsh, J. L.; Townsend, J. C.; Salas, A. O.; Samareh, J. A.; Mukhopadhyay, V.; Barthelemy, J.-F.

2000-01-01

An objective of the High Performance Computing and Communication Program at the NASA Langley Research Center is to demonstrate multidisciplinary shape and sizing optimization of a complete aerospace vehicle configuration by using high-fidelity, finite element structural analysis and computational fluid dynamics aerodynamic analysis in a distributed, heterogeneous computing environment that includes high performance parallel computing. A software system has been designed and implemented to integrate a set of existing discipline analysis codes, some of them computationally intensive, into a distributed computational environment for the design of a highspeed civil transport configuration. The paper describes the engineering aspects of formulating the optimization by integrating these analysis codes and associated interface codes into the system. The discipline codes are integrated by using the Java programming language and a Common Object Request Broker Architecture (CORBA) compliant software product. A companion paper presents currently available results.

A Mapping from the Human Factors Analysis and Classification System (DOD-HFACS) to the Domains of Human Systems Integration (HSI)

DTIC Science & Technology

2009-11-01

Equation Chapter 1 Section 1 A MAPPING FROM THE HUMAN FACTORS ANALYSIS AND CLASSIFICATION SYSTEM (DOD...OMB control number. 1. REPORT DATE NOV 2009 2. REPORT TYPE 3. DATES COVERED 4. TITLE AND SUBTITLE A Mapping from the Human Factors Analysis ...7 The Human Factors Analysis and Classification System .................................................. 7 Mapping of DoD

Varied Human Tolerance to the Combined Conditions of Low Contrast and Diminished Luminance: A Quasi-Meta Analysis

DTIC Science & Technology

2017-08-30

as being three-fold: 1) a measurement of the integrity of both the central and peripheral visual processing centers; 2) an indicator of detail...visual assessment task 12 integral to the Army’s Class 1 Flight Physical (Ginsburg, 1981 and 1984; Bachman & Behar, 1986). During a Class 1 flight...systems. Meta-analysis has been defined as the statistical analysis of a collection of analytical results for the purpose of integrating the findings

Analyzing Distributed Functions in an Integrated Hazard Analysis

NASA Technical Reports Server (NTRS)

Morris, A. Terry; Massie, Michael J.

2010-01-01

Large scale integration of today's aerospace systems is achievable through the use of distributed systems. Validating the safety of distributed systems is significantly more difficult as compared to centralized systems because of the complexity of the interactions between simultaneously active components. Integrated hazard analysis (IHA), a process used to identify unacceptable risks and to provide a means of controlling them, can be applied to either centralized or distributed systems. IHA, though, must be tailored to fit the particular system being analyzed. Distributed systems, for instance, must be analyzed for hazards in terms of the functions that rely on them. This paper will describe systems-oriented IHA techniques (as opposed to traditional failure-event or reliability techniques) that should be employed for distributed systems in aerospace environments. Special considerations will be addressed when dealing with specific distributed systems such as active thermal control, electrical power, command and data handling, and software systems (including the interaction with fault management systems). Because of the significance of second-order effects in large scale distributed systems, the paper will also describe how to analyze secondary functions to secondary functions through the use of channelization.

Medical image computing for computer-supported diagnostics and therapy. Advances and perspectives.

PubMed

Handels, H; Ehrhardt, J

2009-01-01

Medical image computing has become one of the most challenging fields in medical informatics. In image-based diagnostics of the future software assistance will become more and more important, and image analysis systems integrating advanced image computing methods are needed to extract quantitative image parameters to characterize the state and changes of image structures of interest (e.g. tumors, organs, vessels, bones etc.) in a reproducible and objective way. Furthermore, in the field of software-assisted and navigated surgery medical image computing methods play a key role and have opened up new perspectives for patient treatment. However, further developments are needed to increase the grade of automation, accuracy, reproducibility and robustness. Moreover, the systems developed have to be integrated into the clinical workflow. For the development of advanced image computing systems methods of different scientific fields have to be adapted and used in combination. The principal methodologies in medical image computing are the following: image segmentation, image registration, image analysis for quantification and computer assisted image interpretation, modeling and simulation as well as visualization and virtual reality. Especially, model-based image computing techniques open up new perspectives for prediction of organ changes and risk analysis of patients and will gain importance in diagnostic and therapy of the future. From a methodical point of view the authors identify the following future trends and perspectives in medical image computing: development of optimized application-specific systems and integration into the clinical workflow, enhanced computational models for image analysis and virtual reality training systems, integration of different image computing methods, further integration of multimodal image data and biosignals and advanced methods for 4D medical image computing. The development of image analysis systems for diagnostic support or operation planning is a complex interdisciplinary process. Image computing methods enable new insights into the patient's image data and have the future potential to improve medical diagnostics and patient treatment.

Debris/Ice/TPS Assessment and Integrated Photographic Analysis of Shuttle Mission STS-103

NASA Technical Reports Server (NTRS)

Katnik, Gregory N.

2000-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for Shuttle mission STS-103. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the External Tank were assessed by the use of computer programs and infrared scanned data during cryogenic loading of the vehicle, followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or in-flight anomalies. This report documents the ice/debris/thermal protection system conditions and integrated photographic analysis of Space Shuttle mission STS-103 and the resulting effect on the Space Shuttle Program.

Debris/Ice/TPS Assessment and Integrated Photographic Analysis of Shuttle Mission STS-91

NASA Technical Reports Server (NTRS)

Katnik, Gregory N.

1998-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for Shuttle mission STS-91. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the External Tank were assessed by the use of computer programs and infrared scanned data during cryogenic loading of the vehicle, followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or in-flight anomalies. This report documents the ice/debris/thermal protection system conditions and integrated photographic analysis of Space Shuttle mission STS-91 and the resulting effect on the Space Shuttle Program.

Debris/Ice/TPS Assessment and Integrated Photographic Analysis of Shuttle Mission STS-93

NASA Technical Reports Server (NTRS)

Katnik, Gregory N.

1999-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for Shuttle mission STS-93. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the External Tank were assessed by the use of computer programs and infrared scanned data during cryogenic loading of the vehicle, followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or in-flight anomalies. This report documents the ice/debris/thermal protection system conditions and integrated photographic analysis findings of Space Shuttle mission STS-93 and the resulting effect on the Space Shuttle Program.

Debris/Ice/TPS Assessment and Integrated Photographic Analysis of Shuttle Mission STS-95

NASA Technical Reports Server (NTRS)

Katnik, Gregory N.

1999-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for Shuttle mission STS-95. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the External Tank were assessed by the use of computer programs and infrared scanned data during cryogenic loading of the vehicle, followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or in-flight anomalies. This report documents the ice/debris/thermal protection system conditions and integrated photographic analysis of Space Shuttle mission STS-95 and the resulting effect on the Space Shuttle Program.

Debris/Ice/TPS Assessment and Integrated Photographic Analysis of Shuttle Mission STS-90

NASA Technical Reports Server (NTRS)

Katnik, Gregory N.

1998-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for Shuttle mission STS-90. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the External Tank were assessed by the use of computer programs and infrared scanned data during cryogenic loading of the vehicle, followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or in-flight anomalies. This report documents the ice/debris/thermal protection system-conditions and integrated photographic analysis of Space Shuttle mission STS-90 and the resulting effect on the Space Shuttle Program.

Debris/Ice/TPS Assessment and Integrated Photographic Analysis of Shuttle Mission STS-89

NASA Technical Reports Server (NTRS)

Katnik, Gregory N.

1998-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for Shuttle mission STS-89. Debris inspections of the flight element and launch pad were performed before and after launch. Icing conditions on the External Tank were assessed by the use of computer programs and infrared scanned data during cryogenic loading of the vehicle, followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or in-flight anomalies. This report documents the ice/debris/thermal protection systems conditions and integrated photographic analysis of Space Shuttle mission STS-89 and the resulting effect on the Space Shuttle Program.

Debris/Ice/TPS Assessment and Integrated Photographic Analysis of Shuttle Mission STS-112

NASA Technical Reports Server (NTRS)

Oliu, Armando

2002-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for Shuttle mission STS-112. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the External Tank were assessed by the use of computer programs and infrared scanned data during cryogenic loading of the vehicle, followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or in-flight anomalies. The report documents the debris/ice/thermal protection system conditions and integrated photographic analysis of Space Shuttle mission STS-112 and the resulting effect of the Space Shuttle Program.

Debris/Ice/TPS Assessment and Integrated Photographic Analysis of Shuttle Mission STS-74

NASA Technical Reports Server (NTRS)

Katnik, Gregory N.; Bowen, Barry C.; Lin, Jill D.

1996-01-01

A debris/ice/thermal protection system (TPS) assessment and integrated photographic analysis was conducted for shuttle mission STS-74. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the External Tank were assessed by the use of computer programs and infrared scanner data during cryogenic loading of the vehicle, followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or in flight anomalies. This report documents the ice/debris/thermal protection system conditions and integrated photographic analysis of shuttle mission STS-74 and the resulting effect on the Space Shuttle Program.

Debris/Ice/TPS Assessment and Integrated Photographic Analysis of Shuttle Mission STS-87

NASA Technical Reports Server (NTRS)

Katnik, Gregory N.

1998-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for Shuttle mission STS-87. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the External Tank were assessed by the-use of computer programs and infrared scanned data during cryogenic loading of the vehicle, followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or in-flight anomalies. This report documents the ice/debris/thermal protection system conditions and integrated photographic analysis of Space Shuttle mission STS-87 and the resulting effect on the Space Shuttle Program.

Debris/ice/tps Assessment and Integrated Photographic Analysis of Shuttle Mission STS-96

NASA Technical Reports Server (NTRS)

Katnik, Gregory N.

1999-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for Shuttle mission STS-96. Debris inspections of the flight elements and launch pad were performed before and after launch. icing conditions on the External Tank were assessed by the use of computer programs and infrared scanned data during cryogenic loading of the vehicle, followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or in-flight anomalies. This report documents the ice/debris/thermal protection system conditions and integrated photographic analysis of Space Shuttle mission STS-96 and the resulting effect on the Space Shuttle Program.

Debris/Ice/TPS Assessment and Integrated Photographic Analysis of Shuttle Mission STS-101

NASA Technical Reports Server (NTRS)

Katnik, Gregory N.

2000-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for Shuttle Mission STS-101. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the External Tank were assessed by the use of computer programs and infrared scanned data during cryogenic loading of the vehicle, followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or in flight anomalies. This report documents the ice/debris/thermal protection system conditions and integrated photographic analysis of Space Shuttle mission STS-101 and the resulting effect on the Space Shuttle Program.

Debris/Ice/TPS Assessment and Integrated Photographic Analysis of Shuttle Mission STS-88

NASA Technical Reports Server (NTRS)

Katnik, Gregory N.

1999-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for Shuttle mission STS-88. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the External Tank were assessed by the use of computer programs and infrared scanned data during cryogenic loading of the vehicle, followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or in-flight anomalies. This report documents the ice/debris/thermal protection system conditions and integrated photographic analysis of Space Shuttle mission STS-88 and the resulting effect on the Space Shuttle Program.

Debris/ice/TPS assessment and integrated photographic analysis of Shuttle Mission STS-64 on 9 August 1994

NASA Technical Reports Server (NTRS)

Davis, J. Bradley; Bowen, Barry C.; Rivera, Jorge E.; Speece, Robert F.; Katnik, Gregory N.

1994-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for Shuttle mission STS-64. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the External Tank were assessed by the use of computer programs, nomographs, and infrared scanner data during cryogenic loading of the vehicle followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or in-flight anomalies. This report documents the ice/debris/thermal protection system conditions and integrated photographic analysis of Shuttle mission STS-64, and the resulting effect on the Space Shuttle Program.

Debris/ice/TPS assessment and integrated photographic analysis of Shuttle mission STS-68

NASA Technical Reports Server (NTRS)

Rivera, Jorge E.; Bowen, Barry C.; Davis, J. Bradley; Speece, Robert F.

1994-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for Shuttle mission STS-68. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the External Tank were assessed by the use of computer programs, nomographs, and infrared scanner data during cryogenic loading of the vehicle followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or in-flight anomalies. This report-documents the ice/debris/thermal protection system conditions and integrated photographic analysis of Shuttle mission STS-68, and the resulting effect on the Space Shuttle Program.

Debris/Ice/TPS Assessment and Integrated Photographic Analysis of Shuttle Mission STS-111

NASA Technical Reports Server (NTRS)

Oliu, Armando

2005-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for Shuttle mission STS-111. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the External Tank were assessed by the use of computer programs and infrared scanned data during cryogenic loading of the vehicle, followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or in-flight anomalies. The report documents the debris/ice/thermal protection system conditions and integrated photographic analysis of Space Shuttle mission STS-111 and the resulting effect of the Space Shuttle Program.

Debris/Ice/TPS Assessment and Integrated Photographic Analysis of Shuttle Mission STS-99

NASA Technical Reports Server (NTRS)

Katnik, Gregory N.

2000-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for Shuttle mission STS-99. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the External Tank were assessed by the use of computer programs and infrared scanned data during cryogenic loading of the vehicle, followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or in-flight anomalies. This report documents the debris/ice/thermal protection system conditions and integrated photographic analysis of Space Shuttle mission STS-99 and the resulting effect on the Space Shuttle Program.

Debris/Ice/TPS Assessment and Integrated Photographic Analysis of Shuttle Mission STS-98

NASA Technical Reports Server (NTRS)

Speece, Robert F.

2004-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for Shuttle Mission STS-98. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the External Tank were assessed by the use of computer programs and infrared scanned data during cryogenic loading of the vehicle, followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or in-flight anomalies. This report documents the debris/ice/thermal protection system conditions and integrated photographic analysis of Space Shuttle mission STS-98 and the resulting effect on the Space Shuttle Program.

Debris/ice/TPS assessment and integrated photographic analysis of shuttle mission STS-63

NASA Technical Reports Server (NTRS)

Katnik, Gregory N.; Bowen, Barry C.; Davis, J. Bradley

1995-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for shuttle mission STS-63. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the external tank were assessed by the use of computer programs, monographs, and infrared scanner data during cryogenic loading of the vehicle followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or in-flight anomalies. This report documents the ice/debris/thermal protection system conditions and integrated photographic analysis of shuttle mission STS-63, and the resulting effect on the space shuttle program.

Debris/ice/TPS assessment and integrated photographic analysis of Shuttle mission STS-66

NASA Technical Reports Server (NTRS)

Katnik, Gregory N.; Bowen, Barry C.; Davis, J. Bradley

1995-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for Shuttle mission STS-66. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the External Tank were assessed by the use of computer program nomographs, and infrared scanner data during cryogenic loading of the vehicle followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or in-flight anomalies. This report documents the ice/debris/thermal protection system conditions and integrated photographic analysis of Shuttle mission STS-66, and the resulting effect on the Space Shuttle Program.

Debris/Ice/TPS Assessment and Integrated Photographic Analysis of Shuttle Mission STS-97

NASA Technical Reports Server (NTRS)

Rivera, Jorge E.; Kelly, J. David (Technical Monitor)

2001-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for Shuttle mission STS-97. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the External Tank were assessed by the use of computer programs and infrared scanned data during cryogenic loading of the vehicle, followed by on-pad visual inspection. High speed photography of the launch were analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or in-flight anomalies. This report documents the debris /ice/thermal protection system conditions and integrated photographic analysis of Space Shuttle mission STS-97 and the resulting effect on the Space Shuttle Program.

Debris/Ice/TPS Assessment and Integrated Photographic Analysis of Shuttle Mission STS-86

NASA Technical Reports Server (NTRS)

Katnik, Gregory N.; Lin, Jill D.

1997-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for Shuttle mission STS-86. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the External Tank were assessed by the use of computer programs and infrared scanned data during cryogenic loading of the vehicle, followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or in-flight anomalies. This report documents the ice/debris/thermal protection system conditions and integrated photographic analysis of Space Shuttle mission STS-86 and the resulting affect on the Space Shuttle Program.

Debris/Ice/TPS Assessment and Integrated Photographic Analysis of Shuttle Mission STS-100

NASA Technical Reports Server (NTRS)

Oliu, Armando

2004-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for Shuttle mission STS-100. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the External Tank were assessed by the use of computer programs and infrared scanned data during cryogenic loading of the vehicle, followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or in-flight anomalies. The report documents the debris/ice/thermal protection system conditions and integrated photographic analysis of Space Shuttle mission STS-100 and the resulting effect of the Space Shuttle Program.

Debris/Ice/TPS Assessment and Integrated Photographic Analysis of Shuttle Mission STS-92

NASA Technical Reports Server (NTRS)

Katnik, Gregory N.

2000-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for Shuttle mission STS-92. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the External Tank were assessed by the use of computer programs and infrared scanned data during cryogenic loading of the vehicle, followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or in-flight anomalies. This report documents the debris/ice/thermal protection system conditions and integrated photographic analysis of Space Shuttle mission STS-92 and the resulting effect, if any, on the Space Shuttle Program.

Debris/ice/TPS assessment and integrated photographic analysis of Shuttle Mission STS-65

NASA Technical Reports Server (NTRS)

Katnik, Gregory N.; Bowen, Barry C.; Davis, J. Bradley

1994-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for shuttle mission STS-65. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the external tank were assessed by the use of computer programs, nomographs, and infrared scanner data during cryogenic loading of the vehicle followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or in-flight anomalies. This report documents the ice/debris/thermal protection system conditions and integrated photographic analysis of shuttle mission STS-65, and the resulting effect on the Space Shuttle Program.

Object-oriented analysis and design of an ECG storage and retrieval system integrated with an HIS.

PubMed

Wang, C; Ohe, K; Sakurai, T; Nagase, T; Kaihara, S

1996-03-01

For a hospital information system, object-oriented methodology plays an increasingly important role, especially for the management of digitized data, e.g., the electrocardiogram, electroencephalogram, electromyogram, spirogram, X-ray, CT and histopathological images, which are not yet computerized in most hospitals. As a first step in an object-oriented approach to hospital information management and storing medical data in an object-oriented database, we connected electrocardiographs to a hospital network and established the integration of ECG storage and retrieval systems with a hospital information system. In this paper, the object-oriented analysis and design of the ECG storage and retrieval systems is reported.

Control/structure interaction conceptual design tool

NASA Technical Reports Server (NTRS)

Briggs, Hugh C.

1990-01-01

The JPL Control/Structure Interaction Program is developing new analytical methods for designing micro-precision spacecraft with controlled structures. One of these, the Conceptual Design Tool, will illustrate innovative new approaches to the integration of multi-disciplinary analysis and design methods. The tool will be used to demonstrate homogeneity of presentation, uniform data representation across analytical methods, and integrated systems modeling. The tool differs from current 'integrated systems' that support design teams most notably in its support for the new CSI multi-disciplinary engineer. The design tool will utilize a three dimensional solid model of the spacecraft under design as the central data organization metaphor. Various analytical methods, such as finite element structural analysis, control system analysis, and mechanical configuration layout, will store and retrieve data from a hierarchical, object oriented data structure that supports assemblies of components with associated data and algorithms. In addition to managing numerical model data, the tool will assist the designer in organizing, stating, and tracking system requirements.

Environmental science applications with Rapid Integrated Mapping and analysis System (RIMS)

NASA Astrophysics Data System (ADS)

Shiklomanov, A.; Prusevich, A.; Gordov, E.; Okladnikov, I.; Titov, A.

2016-11-01

The Rapid Integrated Mapping and analysis System (RIMS) has been developed at the University of New Hampshire as an online instrument for multidisciplinary data visualization, analysis and manipulation with a focus on hydrological applications. Recently it was enriched with data and tools to allow more sophisticated analysis of interdisciplinary data. Three different examples of specific scientific applications with RIMS are demonstrated and discussed. Analysis of historical changes in major components of the Eurasian pan-Arctic water budget is based on historical discharge data, gridded observational meteorological fields, and remote sensing data for sea ice area. Express analysis of the extremely hot and dry summer of 2010 across European Russia is performed using a combination of near-real time and historical data to evaluate the intensity and spatial distribution of this event and its socioeconomic impacts. Integrative analysis of hydrological, water management, and population data for Central Asia over the last 30 years provides an assessment of regional water security due to changes in climate, water use and demography. The presented case studies demonstrate the capabilities of RIMS as a powerful instrument for hydrological and coupled human-natural systems research.

Integrated Microfluidic Gas Sensors for Water Monitoring

NASA Technical Reports Server (NTRS)

Zhu, L.; Sniadecki, N.; DeVoe, D. L.; Beamesderfer, M.; Semancik, S.; DeVoe, D. L.

2003-01-01

A silicon-based microhotplate tin oxide (SnO2) gas sensor integrated into a polymer-based microfluidic system for monitoring of contaminants in water systems is presented. This device is designed to sample a water source, control the sample vapor pressure within a microchannel using integrated resistive heaters, and direct the vapor past the integrated gas sensor for analysis. The sensor platform takes advantage of novel technology allowing direct integration of discrete silicon chips into a larger polymer microfluidic substrate, including seamless fluidic and electrical interconnects between the substrate and silicon chip.

The integrated microbial genome resource of analysis.

PubMed

Checcucci, Alice; Mengoni, Alessio

2015-01-01

Integrated Microbial Genomes and Metagenomes (IMG) is a biocomputational system that allows to provide information and support for annotation and comparative analysis of microbial genomes and metagenomes. IMG has been developed by the US Department of Energy (DOE)-Joint Genome Institute (JGI). IMG platform contains both draft and complete genomes, sequenced by Joint Genome Institute and other public and available genomes. Genomes of strains belonging to Archaea, Bacteria, and Eukarya domains are present as well as those of viruses and plasmids. Here, we provide some essential features of IMG system and case study for pangenome analysis.

Assured Information Flow Capping Architecture.

DTIC Science & Technology

1985-05-01

Air Control System Deployment, ESD-TR-71-371, AD 733 584, Electronic Systems Division, AFSC, Hanscom Air Force Base, MA, November 1971. 3. I. Gitman and...H. Frank, "Economic Analysis of Integrated Voice and Data Networks: A Case Study," Proceedings of the IEEE, November 1978. 4. H. Frank and I. Gitman ... Gitman , "Study Shows Packet Switching Best for Voice Traffic, Too," Data Communications, March 1979. ___ "Economic Analysis of Integrated Voice and

Airspace Systems Program: Next Generation Air Transportation System, NextGen Systems Analysis, Integration and Evaluation Project. Version 1.0; Project Plan

NASA Technical Reports Server (NTRS)

Quon, Leighton

2010-01-01

The key objectives of the NASA ASP are to: Improve mobility, capacity efficiency and access of the airspace system. Improve collaboration, predictability, and flexibility for the airspace users. Enable accurate modeling and simulation of air transportation systems. Accommodate operations of all classes of aircraft. Maintain system safety and environmental protection. In support of these program objectives, the major goal of the NextGen-SAIE Project is to enable the transition of key capacity and efficiency improvements to the NAS. Since many aspects of the NAS are unique to specific airport or airspace environments, demand on various parts of the NAS is not expected to increase equally as system demand grows. SAIE will provide systems level analysis of the NAS characteristics, constraints, and demands such that a suite of capacity-increasing concepts and technologies for system solutions are enabled and facilitated. The technical objectives in support of this goal are the following: Integration, evaluation, and transition of more mature concepts and technologies in an environment that faithfully emulates real-world complexities. Interoperability research and analysis of ASP technologies across ATM functions is performed to facilitate integration and take ASP concepts and technologies to higher Technology Readiness Level (TRL). Analyses are conducted on the program s concepts to identify the system benefits or impacts. System level analysis is conducted to increase understanding of the characteristics and constraints of airspace system and its domains.

Benefit-Cost Analysis of Integrated Paratransit Systems : Volume 1. Executive Summary.

DOT National Transportation Integrated Search

1979-09-01

Integrated Paratransit (IP) is a concept which involves the integration of conventional fixed-route transit with flexibly routed paratransit services to provide the most effective area-wide transit coverage. The report estimates the benefits and cost...

A Review of Diagnostic Techniques for ISHM Applications

NASA Technical Reports Server (NTRS)

Patterson-Hine, Ann; Biswas, Gautam; Aaseng, Gordon; Narasimhan, Sriam; Pattipati, Krishna

2005-01-01

System diagnosis is an integral part of any Integrated System Health Management application. Diagnostic applications make use of system information from the design phase, such as safety and mission assurance analysis, failure modes and effects analysis, hazards analysis, functional models, fault propagation models, and testability analysis. In modern process control and equipment monitoring systems, topological and analytic , models of the nominal system, derived from design documents, are also employed for fault isolation and identification. Depending on the complexity of the monitored signals from the physical system, diagnostic applications may involve straightforward trending and feature extraction techniques to retrieve the parameters of importance from the sensor streams. They also may involve very complex analysis routines, such as signal processing, learning or classification methods to derive the parameters of importance to diagnosis. The process that is used to diagnose anomalous conditions from monitored system signals varies widely across the different approaches to system diagnosis. Rule-based expert systems, case-based reasoning systems, model-based reasoning systems, learning systems, and probabilistic reasoning systems are examples of the many diverse approaches ta diagnostic reasoning. Many engineering disciplines have specific approaches to modeling, monitoring and diagnosing anomalous conditions. Therefore, there is no "one-size-fits-all" approach to building diagnostic and health monitoring capabilities for a system. For instance, the conventional approaches to diagnosing failures in rotorcraft applications are very different from those used in communications systems. Further, online and offline automated diagnostic applications are integrated into an operations framework with flight crews, flight controllers and maintenance teams. While the emphasis of this paper is automation of health management functions, striking the correct balance between automated and human-performed tasks is a vital concern.

Integration of chemical and biological treatments for textile industry wastewater: a possible zero-discharge system.

PubMed

Lee, H H; Chen, G; Yue, P L

2001-01-01

Theoretical and experimental studies have established that integrated treatment systems (mostly chemical and biological) for various industrial wastewaters can achieve better quality of treatment and can be cost-effective. In the present study, the objective is to minimize the use of process water in the textile industry by an economical recycle and reuse scheme. The textile wastewater was first characterized in terms of COD, BOD5, salinity and color. In order to recycle such wastewater, the contaminants should be mineralized and/or removed according to the reusable textile water quality standards. Typical results show that this is achievable. An economic analysis has been conducted on the proposed integrated system. The economic analysis shows that the integrated system is economically more attractive than any of the single treatment technologies for achieving the same target of treatment. The information presented in this paper provides a feasible option for the reduction of effluent discharges in the textile industry.

Microblogging for Class: An Analysis of Affective, Cognitive, Personal Integrative, and Social Integrative Gratifications

ERIC Educational Resources Information Center

Gant, Camilla; Hadley, Patrick D.

2014-01-01

This study shows that undergraduate students can gratify cognitive, affective, social integrative, and personal integrative needs microblogging via a learning management system discussion tool. Moreover, the researchers find that microblogging about news regarding mass media events and issues via Blackboard heightened engagement, expanded…

Energy loss analysis of an integrated space power distribution system

NASA Technical Reports Server (NTRS)

Kankam, M. D.; Ribeiro, P. F.

1992-01-01

The results of studies related to conceptual topologies of an integrated utility-like space power system are described. The system topologies are comparatively analyzed by considering their transmission energy losses as functions of mainly distribution voltage level and load composition. The analysis is expedited by use of a Distribution System Analysis and Simulation (DSAS) software. This recently developed computer program by the Electric Power Research Institute (EPRI) uses improved load models to solve the power flow within the system. However, present shortcomings of the software with regard to space applications, and incompletely defined characteristics of a space power system make the results applicable to only the fundamental trends of energy losses of the topologies studied. Accountability, such as included, for the effects of the various parameters on the system performance can constitute part of a planning tool for a space power distribution system.

Rocket engine system reliability analyses using probabilistic and fuzzy logic techniques

NASA Technical Reports Server (NTRS)

Hardy, Terry L.; Rapp, Douglas C.

1994-01-01

The reliability of rocket engine systems was analyzed by using probabilistic and fuzzy logic techniques. Fault trees were developed for integrated modular engine (IME) and discrete engine systems, and then were used with the two techniques to quantify reliability. The IRRAS (Integrated Reliability and Risk Analysis System) computer code, developed for the U.S. Nuclear Regulatory Commission, was used for the probabilistic analyses, and FUZZYFTA (Fuzzy Fault Tree Analysis), a code developed at NASA Lewis Research Center, was used for the fuzzy logic analyses. Although both techniques provided estimates of the reliability of the IME and discrete systems, probabilistic techniques emphasized uncertainty resulting from randomness in the system whereas fuzzy logic techniques emphasized uncertainty resulting from vagueness in the system. Because uncertainty can have both random and vague components, both techniques were found to be useful tools in the analysis of rocket engine system reliability.

Nuclear Hybrid Energy Systems Initial Integrated Case Study Development and Analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Harrison, Thomas J.; Greenwood, Michael Scott

The US Department of Energy Office of Nuclear Energy established the Nuclear Hybrid Energy System (NHES) project to develop a systematic, rigorous, technically accurate set of methods to model, analyze, and optimize the integration of dispatchable nuclear, fossil, and electric storage with an industrial customer. Ideally, the optimized integration of these systems will provide economic and operational benefits to the overall system compared to independent operation, and it will enhance the stability and responsiveness of the grid as intermittent, nondispatchable, renewable resources provide a greater share of grid power.

Analysis of Logistics in Support of a Human Lunar Outpost

NASA Technical Reports Server (NTRS)

Cirillo, William; Earle, Kevin; Goodliff, Kandyce; Reeves, j. D.; Andrashko, Mark; Merrill, R. Gabe; Stromgren, Chel

2008-01-01

Strategic level analysis of the integrated behavior of lunar transportation system and lunar surface system architecture options is performed to inform NASA Constellation Program senior management on the benefit, viability, affordability, and robustness of system design choices. This paper presents an overview of the approach used to perform the campaign (strategic) analysis, with an emphasis on the logistics modeling and the impacts of logistics resupply on campaign behavior. An overview of deterministic and probabilistic analysis approaches is provided, with a discussion of the importance of each approach to understanding the integrated system behavior. The logistics required to support lunar surface habitation are analyzed from both 'macro-logistics' and 'micro-logistics' perspectives, where macro-logistics focuses on the delivery of goods to a destination and micro-logistics focuses on local handling of re-supply goods at a destination. An example campaign is provided to tie the theories of campaign analysis to results generation capabilities.

Antenna analysis using properties of metamaterials

NASA Astrophysics Data System (ADS)

Mitra, Atindra K.; Hu, Colin; Maxwell, Kasandra

2010-04-01

As part of the Student Internship Programs at Wright-Patterson Air Force Base, including the AFRL Wright Scholar Program for High School Students and the AFRL STEP Program, sample results from preliminary investigation and analysis of integrated antenna structures are reported. Investigation of these novel integrated antenna geometries can be interpreted as a continuation of systems analysis under the general topic area of potential integrated apertures for future software radar/radio solutions [1] [2]. Specifically, the categories of novel integrated aperture geometries investigated in this paper include slotted-fractal structures on microstrip rectangular patch antenna models in tandem with the analysis of exotic substrate materials comprised of a type of synthesized electromagnetic structure known as metamaterials [8] - [10].

Dynamic Mobility Applications Policy Analysis: Policy and Institutional Issues for Integrated Dynamic Transit Operations (IDTO). [supporting datasets

DOT National Transportation Integrated Search

2015-01-27

The datasets in this zip file are in support of Intelligent Transportation Systems Joint Program Office (ITS JPO) report FHWA-JPO-14-134, "Dynamic Mobility Applications Policy Analysis: Policy and Institutional Issues for Integrated Dynamic Transit O...

Electric Sector Integration | Energy Analysis | NREL

Science.gov Websites

investigates the potential impacts of expanding renewable technology deployment on grid operations and Electric System Flexibility and Storage Impacts on Conventional Generators Transmission Infrastructure Generation Our grid integration studies use state-of-the-art modeling and analysis to evaluate the impacts of

Aviation System Analysis Capability Executive Assistant Analyses

NASA Technical Reports Server (NTRS)

Roberts, Eileen; Kostiuk, Peter

1999-01-01

This document describes the analyses that may be incorporated into the Aviation System Analysis Capability Executive Assistant. The document will be used as a discussion tool to enable NASA and other integrated aviation system entities to evaluate, discuss, and prioritize analyses.

Design and integration of a generic disposable array-compatible sensor housing into an integrated disposable indirect microfluidic flow injection analysis system.

PubMed

Rapp, Bastian E; Schickling, Benjamin; Prokop, Jürgen; Piotter, Volker; Rapp, Michael; Länge, Kerstin

2011-10-01

We describe an integration strategy for arbitrary sensors intended to be used as biosensors in biomedical or bioanalytical applications. For such devices ease of handling (by a potential end user) as well as strict disposable usage are of importance. Firstly we describe a generic array compatible polymer sensor housing with an effective sample volume of 1.55 μl. This housing leaves the sensitive surface of the sensor accessible for the application of biosensing layers even after the embedding. In a second step we show how this sensor housing can be used in combination with a passive disposable microfluidic chip to set up arbitrary 8-fold sensor arrays and how such a system can be complemented with an indirect microfluidic flow injection analysis (FIA) system. This system is designed in a way that it strictly separates between disposable and reusable components- by introducing tetradecane as an intermediate liquid. This results in a sensor system compatible with the demands of most biomedical applications. Comparative measurements between a classical macroscopic FIA system and this integrated indirect microfluidic system are presented. We use a surface acoustic wave (SAW) sensor as an exemplary detector in this work.

Modular AUV System with Integrated Real-Time Water Quality Analysis.

PubMed

Eichhorn, Mike; Ament, Christoph; Jacobi, Marco; Pfuetzenreuter, Torsten; Karimanzira, Divas; Bley, Kornelia; Boer, Michael; Wehde, Henning

2018-06-05

This paper describes the concept, the technical implementation and the practical application of a miniaturized sensor system integrated into an autonomous underwater vehicle (AUV) for real-time acquisition of water quality parameters. The main application field of the presented system is the analysis of the discharge of nitrates into Norwegian fjords near aqua farms. The presented system was developed within the research project SALMON (Sea Water Quality Monitoring and Management) over a three-year period. The development of the sensor system for water quality parameters represented a significant challenge for the research group, as it was to be integrated in the payload unit of the autonomous underwater vehicle in compliance with the underwater environmental conditions. The German company -4H- JENA engineering GmbH (4HJE), with experience in optical in situ-detection of nutrients, designed and built the measurement system. As a carrier platform, the remotely operated vehicle (ROV) "CWolf" from Fraunhofer-Institut für Optronik, Systemtechnik und Bildauswertung - Institutsteil Angewandte Systemtechnik (IOSB-AST) modified to an AUV was deployed. The concept presented illustrates how the measurement system can be integrated easily into the vehicle with a minimum of hard- and software technical interfaces.

Lie symmetry analysis, Bäcklund transformations, and exact solutions of a (2 + 1)-dimensional Boiti-Leon-Pempinelli system

NASA Astrophysics Data System (ADS)

Zhao, Zhonglong; Han, Bo

2017-10-01

In this paper, the Lie symmetry analysis method is employed to investigate the Lie point symmetries and the one-parameter transformation groups of a (2 + 1)-dimensional Boiti-Leon-Pempinelli system. By using Ibragimov's method, the optimal system of one-dimensional subalgebras of this system is constructed. Truncated Painlevé analysis is used for deriving the Bäcklund transformation. The method of constructing lump-type solutions of integrable equations by means of Bäcklund transformation is first presented. Meanwhile, the lump-type solutions of the (2 + 1)-dimensional Boiti-Leon-Pempinelli system are obtained. The lump-type wave is one kind of rogue wave. The fusion-type N-solitary wave solutions are also constructed. In addition, this system is integrable in terms of the consistent Riccati expansion method.

Post2 End-to-End Descent and Landing Simulation for ALHAT Design Analysis Cycle 2

NASA Technical Reports Server (NTRS)

Davis, Jody L.; Striepe, Scott A.; Maddock, Robert W.; Johnson, Andrew E.; Paschall, Stephen C., II

2010-01-01

The ALHAT project is an agency-level program involving NASA centers, academia, and industry, with a primary goal to develop a safe, autonomous, precision-landing system for robotic and crew-piloted lunar and planetary descent vehicles. POST2 is used as the 6DOF descent and landing trajectory simulation for determining integrated system performance of ALHAT landing-system models and lunar environment models. This paper presents updates in the development of the ALHAT POST2 simulation, as well as preliminary system performance analysis for ALDAC-2 used for the testing and assessment of ALHAT system models. The ALDAC-2 POST2 Monte Carlo simulation results have been generated and focus on HRN model performance with the fully integrated system, as well performance improvements of AGNC and TSAR model since the previous design analysis cycle

An integrated exhaust gas analysis system with self-contained data processing and automatic calibration

NASA Technical Reports Server (NTRS)

Anderson, R. C.; Summers, R. L.

1981-01-01

An integrated gas analysis system designed to operate in automatic, semiautomatic, and manual modes from a remote control panel is described. The system measures the carbon monoxide, oxygen, water vapor, total hydrocarbons, carbon dioxide, and oxides of nitrogen. A pull through design provides increased reliability and eliminates the need for manual flow rate adjustment and pressure correction. The system contains two microprocessors to range the analyzers, calibrate the system, process the raw data to units of concentration, and provides information to the facility research computer and to the operator through terminal and the control panels. After initial setup, the system operates for several hours without significant operator attention.

Supporting community annotation and user collaboration in the integrated microbial genomes (IMG) system

DOE PAGES

Chen, I-Min A.; Markowitz, Victor M.; Palaniappan, Krishna; ...

2016-04-26

Background: The exponential growth of genomic data from next generation technologies renders traditional manual expert curation effort unsustainable. Many genomic systems have included community annotation tools to address the problem. Most of these systems adopted a "Wiki-based" approach to take advantage of existing wiki technologies, but encountered obstacles in issues such as usability, authorship recognition, information reliability and incentive for community participation. Results: Here, we present a different approach, relying on tightly integrated method rather than "Wiki-based" method, to support community annotation and user collaboration in the Integrated Microbial Genomes (IMG) system. The IMG approach allows users to use existingmore » IMG data warehouse and analysis tools to add gene, pathway and biosynthetic cluster annotations, to analyze/reorganize contigs, genes and functions using workspace datasets, and to share private user annotations and workspace datasets with collaborators. We show that the annotation effort using IMG can be part of the research process to overcome the user incentive and authorship recognition problems thus fostering collaboration among domain experts. The usability and reliability issues are addressed by the integration of curated information and analysis tools in IMG, together with DOE Joint Genome Institute (JGI) expert review. Conclusion: By incorporating annotation operations into IMG, we provide an integrated environment for users to perform deeper and extended data analysis and annotation in a single system that can lead to publications and community knowledge sharing as shown in the case studies.« less

Supporting community annotation and user collaboration in the integrated microbial genomes (IMG) system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, I-Min A.; Markowitz, Victor M.; Palaniappan, Krishna

Background: The exponential growth of genomic data from next generation technologies renders traditional manual expert curation effort unsustainable. Many genomic systems have included community annotation tools to address the problem. Most of these systems adopted a "Wiki-based" approach to take advantage of existing wiki technologies, but encountered obstacles in issues such as usability, authorship recognition, information reliability and incentive for community participation. Results: Here, we present a different approach, relying on tightly integrated method rather than "Wiki-based" method, to support community annotation and user collaboration in the Integrated Microbial Genomes (IMG) system. The IMG approach allows users to use existingmore » IMG data warehouse and analysis tools to add gene, pathway and biosynthetic cluster annotations, to analyze/reorganize contigs, genes and functions using workspace datasets, and to share private user annotations and workspace datasets with collaborators. We show that the annotation effort using IMG can be part of the research process to overcome the user incentive and authorship recognition problems thus fostering collaboration among domain experts. The usability and reliability issues are addressed by the integration of curated information and analysis tools in IMG, together with DOE Joint Genome Institute (JGI) expert review. Conclusion: By incorporating annotation operations into IMG, we provide an integrated environment for users to perform deeper and extended data analysis and annotation in a single system that can lead to publications and community knowledge sharing as shown in the case studies.« less

Integrated analysis of engine structures

NASA Technical Reports Server (NTRS)

Chamis, C. C.

1981-01-01

The need for light, durable, fuel efficient, cost effective aircraft requires the development of engine structures which are flexible, made from advaced materials (including composites), resist higher temperatures, maintain tighter clearances and have lower maintenance costs. The formal quantification of any or several of these requires integrated computer programs (multilevel and/or interdisciplinary analysis programs interconnected) for engine structural analysis/design. Several integrated analysis computer prorams are under development at Lewis Reseach Center. These programs include: (1) COBSTRAN-Composite Blade Structural Analysis, (2) CODSTRAN-Composite Durability Structural Analysis, (3) CISTRAN-Composite Impact Structural Analysis, (4) STAEBL-StruTailoring of Engine Blades, and (5) ESMOSS-Engine Structures Modeling Software System. Three other related programs, developed under Lewis sponsorship, are described.

Biometric Attendance and Big Data Analysis for Optimizing Work Processes.

PubMed

Verma, Neetu; Xavier, Teenu; Agrawal, Deepak

2016-01-01

Although biometric attendance management is available, large healthcare organizations have difficulty in big data analysis for optimization of work processes. The aim of this project was to assess the implementation of a biometric attendance system and its utility following big data analysis. In this prospective study the implementation of biometric system was evaluated over 3 month period at our institution. Software integration with other existing systems for data analysis was also evaluated. Implementation of the biometric system could be successfully done over a two month period with enrollment of 10,000 employees into the system. However generating reports and taking action this large number of staff was a challenge. For this purpose software was made for capturing the duty roster of each employee and integrating it with the biometric system and adding an SMS gateway. This helped in automating the process of sending SMSs to each employee who had not signed in. Standalone biometric systems have limited functionality in large organizations unless it is meshed with employee duty roster.

Integrated Multidisciplinary Optimization Objects

NASA Technical Reports Server (NTRS)

Alston, Katherine

2014-01-01

OpenMDAO is an open-source MDAO framework. It is used to develop an integrated analysis and design environment for engineering challenges. This Phase II project integrated additional modules and design tools into OpenMDAO to perform discipline-specific analysis across multiple flight regimes at varying levels of fidelity. It also showcased a refined system architecture that allows the system to be less customized to a specific configuration (i.e., system and configuration separation). By delivering a capable and validated MDAO system along with a set of example applications to be used as a template for future users, this work greatly expands NASA's high-fidelity, physics-based MDAO capabilities and enables the design of revolutionary vehicles in a cost-effective manner. This proposed work complements M4 Engineering's expertise in developing modeling and simulation toolsets that solve relevant subsonic, supersonic, and hypersonic demonstration applications.

Execution Of Systems Integration Principles During Systems Engineering Design

DTIC Science & Technology

2016-09-01

This thesis discusses integration failures observed by DOD and non - DOD systems as, inadequate stakeholder analysis, incomplete problem space and design ... design , development, test and deployment of a system. A lifecycle structure consists of phases within a methodology or process model. There are many...investigate design decisions without the need to commit to physical forms; “ experimental investigation using a model yields design or operational

Performance Analysis on Carrier Phase-Based Tightly-Coupled GPS/BDS/INS Integration in GNSS Degraded and Denied Environments

PubMed Central

Han, Houzeng; Wang, Jian; Wang, Jinling; Tan, Xinglong

2015-01-01

The integration of Global Navigation Satellite Systems (GNSS) carrier phases with Inertial Navigation System (INS) measurements is essential to provide accurate and continuous position, velocity and attitude information, however it is necessary to fix ambiguities rapidly and reliably to obtain high accuracy navigation solutions. In this paper, we present the notion of combining the Global Positioning System (GPS), the BeiDou Navigation Satellite System (BDS) and low-cost micro-electro-mechanical sensors (MEMS) inertial systems for reliable navigation. An adaptive multipath factor-based tightly-coupled (TC) GPS/BDS/INS integration algorithm is presented and the overall performance of the integrated system is illustrated. A twenty seven states TC GPS/BDS/INS model is adopted with an extended Kalman filter (EKF), which is carried out by directly fusing ambiguity fixed double-difference (DD) carrier phase measurements with the INS predicted pseudoranges to estimate the error states. The INS-aided integer ambiguity resolution (AR) strategy is developed by using a dynamic model, a two-step estimation procedure is applied with adaptively estimated covariance matrix to further improve the AR performance. A field vehicular test was carried out to demonstrate the positioning performance of the combined system. The results show the TC GPS/BDS/INS system significantly improves the single-epoch AR reliability as compared to that of GPS/BDS-only or single satellite navigation system integrated strategy, especially for high cut-off elevations. The AR performance is also significantly improved for the combined system with adaptive covariance matrix in the presence of low elevation multipath related to the GNSS-only case. A total of fifteen simulated outage tests also show that the time to relock of the GPS/BDS signals is shortened, which improves the system availability. The results also indicate that TC integration system achieves a few centimeters accuracy in positioning based on the comparison analysis and covariance analysis, even in harsh environments (e.g., in urban canyons), thus we can see the advantage of positioning at high cut-off elevations that the combined GPS/BDS brings. PMID:25875191

Performance analysis on carrier phase-based tightly-coupled GPS/BDS/INS integration in GNSS degraded and denied environments.

PubMed

Han, Houzeng; Wang, Jian; Wang, Jinling; Tan, Xinglong

2015-04-14

The integration of Global Navigation Satellite Systems (GNSS) carrier phases with Inertial Navigation System (INS) measurements is essential to provide accurate and continuous position, velocity and attitude information, however it is necessary to fix ambiguities rapidly and reliably to obtain high accuracy navigation solutions. In this paper, we present the notion of combining the Global Positioning System (GPS), the BeiDou Navigation Satellite System (BDS) and low-cost micro-electro-mechanical sensors (MEMS) inertial systems for reliable navigation. An adaptive multipath factor-based tightly-coupled (TC) GPS/BDS/INS integration algorithm is presented and the overall performance of the integrated system is illustrated. A twenty seven states TC GPS/BDS/INS model is adopted with an extended Kalman filter (EKF), which is carried out by directly fusing ambiguity fixed double-difference (DD) carrier phase measurements with the INS predicted pseudoranges to estimate the error states. The INS-aided integer ambiguity resolution (AR) strategy is developed by using a dynamic model, a two-step estimation procedure is applied with adaptively estimated covariance matrix to further improve the AR performance. A field vehicular test was carried out to demonstrate the positioning performance of the combined system. The results show the TC GPS/BDS/INS system significantly improves the single-epoch AR reliability as compared to that of GPS/BDS-only or single satellite navigation system integrated strategy, especially for high cut-off elevations. The AR performance is also significantly improved for the combined system with adaptive covariance matrix in the presence of low elevation multipath related to the GNSS-only case. A total of fifteen simulated outage tests also show that the time to relock of the GPS/BDS signals is shortened, which improves the system availability. The results also indicate that TC integration system achieves a few centimeters accuracy in positioning based on the comparison analysis and covariance analysis, even in harsh environments (e.g., in urban canyons), thus we can see the advantage of positioning at high cut-off elevations that the combined GPS/BDS brings.

The Integration of Multi-State Clarus Data into Data Visualization Tools

DOT National Transportation Integrated Search

2011-12-20

This project focused on the integration of all Clarus Data into the Regional Integrated Transportation Information System (RITIS) for real-time situational awareness and historical safety data analysis. The initial outcomes of this project are the fu...

Benefit-Cost Analysis of Integrated Paratransit Systems : Volume 4. Issues in Community Acceptance and IP Implementation.

DOT National Transportation Integrated Search

1979-09-01

The report describes various factors which influence community acceptance of integrated paratransit (IP) systems. In order to fully explore past events in those communities which have already accepted IP, a case study approach has been used. Seven we...

Integrated restructurable flight control system demonstration results

NASA Technical Reports Server (NTRS)

Weiss, Jerold L.; Hsu, John Y.

1987-01-01

The purpose of this study was to examine the complementary capabilities of several restructurable flight control system (RFCS) concepts through the integration of these technologies into a complete system. Performance issues were addressed through a re-examination of RFCS functional requirements, and through a qualitative analysis of the design issues that, if properly addressed during integration, will lead to the highest possible degree of fault-tolerant performance. Software developed under previous phases of this contract and under NAS1-18004 was modified and integrated into a complete RFCS subroutine for NASA's B-737 simulation. The integration of these modules involved the development of methods for dealing with the mismatch between the outputs of the failure detection module and the input requirements of the automatic control system redesign module. The performance of this demonstration system was examined through extensive simulation trials.

Operationally Efficient Propulsion System Study (OEPSS) Data Book. Volume 8; Integrated Booster Propulsion Module (BPM) Engine Start Dynamics

NASA Technical Reports Server (NTRS)

Kemp, Victoria R.

1992-01-01

A fluid-dynamic, digital-transient computer model of an integrated, parallel propulsion system was developed for the CDC mainframe and the SUN workstation computers. Since all STME component designs were used for the integrated system, computer subroutines were written characterizing the performance and geometry of all the components used in the system, including the manifolds. Three transient analysis reports were completed. The first report evaluated the feasibility of integrated engine systems in regards to the start and cutoff transient behavior. The second report evaluated turbopump out and combined thrust chamber/turbopump out conditions. The third report presented sensitivity study results in staggered gas generator spin start and in pump performance characteristics.

Information Requirements for Integrating Spatially Discrete, Feature-Based Earth Observations

NASA Astrophysics Data System (ADS)

Horsburgh, J. S.; Aufdenkampe, A. K.; Lehnert, K. A.; Mayorga, E.; Hsu, L.; Song, L.; Zaslavsky, I.; Valentine, D. L.

2014-12-01

Several cyberinfrastructures have emerged for sharing observational data collected at densely sampled and/or highly instrumented field sites. These include the CUAHSI Hydrologic Information System (HIS), the Critical Zone Observatory Integrated Data Management System (CZOData), the Integrated Earth Data Applications (IEDA) and EarthChem system, and the Integrated Ocean Observing System (IOOS). These systems rely on standard data encodings and, in some cases, standard semantics for classes of geoscience data. Their focus is on sharing data on the Internet via web services in domain specific encodings or markup languages. While they have made progress in making data available, it still takes investigators significant effort to discover and access datasets from multiple repositories because of inconsistencies in the way domain systems describe, encode, and share data. Yet, there are many scenarios that require efficient integration of these data types across different domains. For example, understanding a soil profile's geochemical response to extreme weather events requires integration of hydrologic and atmospheric time series with geochemical data from soil samples collected over various depth intervals from soil cores or pits at different positions on a landscape. Integrated access to and analysis of data for such studies are hindered because common characteristics of data, including time, location, provenance, methods, and units are described differently within different systems. Integration requires syntactic and semantic translations that can be manual, error-prone, and lossy. We report information requirements identified as part of our work to define an information model for a broad class of earth science data - i.e., spatially-discrete, feature-based earth observations resulting from in-situ sensors and environmental samples. We sought to answer the question: "What information must accompany observational data for them to be archivable and discoverable within a publication system as well as interpretable once retrieved from such a system for analysis and (re)use?" We also describe development of multiple functional schemas (i.e., physical implementations for data storage, transfer, and archival) for the information model that capture the requirements reported here.

Analysis of all-optical temporal integrator employing phased-shifted DFB-SOA.

PubMed

Jia, Xin-Hong; Ji, Xiao-Ling; Xu, Cong; Wang, Zi-Nan; Zhang, Wei-Li

2014-11-17

All-optical temporal integrator using phase-shifted distributed-feedback semiconductor optical amplifier (DFB-SOA) is investigated. The influences of system parameters on its energy transmittance and integration error are explored in detail. The numerical analysis shows that, enhanced energy transmittance and integration time window can be simultaneously achieved by increased injected current in the vicinity of lasing threshold. We find that the range of input pulse-width with lower integration error is highly sensitive to the injected optical power, due to gain saturation and induced detuning deviation mechanism. The initial frequency detuning should also be carefully chosen to suppress the integration deviation with ideal waveform output.

MEMS Technology for Space Applications

NASA Technical Reports Server (NTRS)

vandenBerg, A.; Spiering, V. L.; Lammerink, T. S. J.; Elwenspoek, M.; Bergveld, P.

1995-01-01

Micro-technology enables the manufacturing of all kinds of components for miniature systems or micro-systems, such as sensors, pumps, valves, and channels. The integration of these components into a micro-electro-mechanical system (MEMS) drastically decreases the total system volume and mass. These properties, combined with the increasing need for monitoring and control of small flows in (bio)chemical experiments, makes MEMS attractive for space applications. The level of integration and applied technology depends on the product demands and the market. The ultimate integration is process integration, which results in a one-chip system. An example of process integration is a dosing system of pump, flow sensor, micromixer, and hybrid feedback electronics to regulate the flow. However, for many applications, a hybrid integration of components is sufficient and offers the advantages of design flexibility and even the exchange of components in the case of a modular set up. Currently, we are working on hybrid integration of all kinds of sensors (physical and chemical) and flow system modules towards a modular system; the micro total analysis system (micro TAS). The substrate contains electrical connections as in a printed circuit board (PCB) as well as fluid channels for a circuit channel board (CCB) which, when integrated, form a mixed circuit board (MCB).

Flight elements: Fault detection and fault management

NASA Technical Reports Server (NTRS)

Lum, H.; Patterson-Hine, A.; Edge, J. T.; Lawler, D.

1990-01-01

Fault management for an intelligent computational system must be developed using a top down integrated engineering approach. An approach proposed includes integrating the overall environment involving sensors and their associated data; design knowledge capture; operations; fault detection, identification, and reconfiguration; testability; causal models including digraph matrix analysis; and overall performance impacts on the hardware and software architecture. Implementation of the concept to achieve a real time intelligent fault detection and management system will be accomplished via the implementation of several objectives, which are: Development of fault tolerant/FDIR requirement and specification from a systems level which will carry through from conceptual design through implementation and mission operations; Implementation of monitoring, diagnosis, and reconfiguration at all system levels providing fault isolation and system integration; Optimize system operations to manage degraded system performance through system integration; and Lower development and operations costs through the implementation of an intelligent real time fault detection and fault management system and an information management system.

Air Vehicle Integration and Technology Research (AVIATR). Task Order 0003: Condition-Based Maintenance Plus Structural Integrity (CBM+SI) Demonstration (April 2011 to August 2011)

DTIC Science & Technology

2011-08-01

investigated. Implementation of this technology into the maintenance framework depends on several factors, including safety of the structural system, cost... Maintenance Parameters The F-15 Program has indicated that, in practice , maintenance actions are generally performed on flight hour multiples of 200...Risk Analysis or the Perform Cost Benefit Analysis sections of the flowchart. 4.6. Determine System Configurations The current maintenance practice

Integrated Safety Analysis Tiers

NASA Technical Reports Server (NTRS)

Shackelford, Carla; McNairy, Lisa; Wetherholt, Jon

2009-01-01

Commercial partnerships and organizational constraints, combined with complex systems, may lead to division of hazard analysis across organizations. This division could cause important hazards to be overlooked, causes to be missed, controls for a hazard to be incomplete, or verifications to be inefficient. Each organization s team must understand at least one level beyond the interface sufficiently enough to comprehend integrated hazards. This paper will discuss various ways to properly divide analysis among organizations. The Ares I launch vehicle integrated safety analyses effort will be utilized to illustrate an approach that addresses the key issues and concerns arising from multiple analysis responsibilities.

Integrating automated structured analysis and design with Ada programming support environments

NASA Technical Reports Server (NTRS)

Hecht, Alan; Simmons, Andy

1986-01-01

Ada Programming Support Environments (APSE) include many powerful tools that address the implementation of Ada code. These tools do not address the entire software development process. Structured analysis is a methodology that addresses the creation of complete and accurate system specifications. Structured design takes a specification and derives a plan to decompose the system subcomponents, and provides heuristics to optimize the software design to minimize errors and maintenance. It can also produce the creation of useable modules. Studies have shown that most software errors result from poor system specifications, and that these errors also become more expensive to fix as the development process continues. Structured analysis and design help to uncover error in the early stages of development. The APSE tools help to insure that the code produced is correct, and aid in finding obscure coding errors. However, they do not have the capability to detect errors in specifications or to detect poor designs. An automated system for structured analysis and design TEAMWORK, which can be integrated with an APSE to support software systems development from specification through implementation is described. These tools completement each other to help developers improve quality and productivity, as well as to reduce development and maintenance costs. Complete system documentation and reusable code also resultss from the use of these tools. Integrating an APSE with automated tools for structured analysis and design provide capabilities and advantages beyond those realized with any of these systems used by themselves.

Automated microfluidic devices integrating solid-phase extraction, fluorescent labeling, and microchip electrophoresis for preterm birth biomarker analysis.

PubMed

Sahore, Vishal; Sonker, Mukul; Nielsen, Anna V; Knob, Radim; Kumar, Suresh; Woolley, Adam T

2018-01-01

We have developed multichannel integrated microfluidic devices for automated preconcentration, labeling, purification, and separation of preterm birth (PTB) biomarkers. We fabricated multilayer poly(dimethylsiloxane)-cyclic olefin copolymer (PDMS-COC) devices that perform solid-phase extraction (SPE) and microchip electrophoresis (μCE) for automated PTB biomarker analysis. The PDMS control layer had a peristaltic pump and pneumatic valves for flow control, while the PDMS fluidic layer had five input reservoirs connected to microchannels and a μCE system. The COC layers had a reversed-phase octyl methacrylate porous polymer monolith for SPE and fluorescent labeling of PTB biomarkers. We determined μCE conditions for two PTB biomarkers, ferritin (Fer) and corticotropin-releasing factor (CRF). We used these integrated microfluidic devices to preconcentrate and purify off-chip-labeled Fer and CRF in an automated fashion. Finally, we performed a fully automated on-chip analysis of unlabeled PTB biomarkers, involving SPE, labeling, and μCE separation with 1 h total analysis time. These integrated systems have strong potential to be combined with upstream immunoaffinity extraction, offering a compact sample-to-answer biomarker analysis platform. Graphical abstract Pressure-actuated integrated microfluidic devices have been developed for automated solid-phase extraction, fluorescent labeling, and microchip electrophoresis of preterm birth biomarkers.

Mines Systems Safety Improvement Using an Integrated Event Tree and Fault Tree Analysis

NASA Astrophysics Data System (ADS)

Kumar, Ranjan; Ghosh, Achyuta Krishna

2017-04-01

Mines systems such as ventilation system, strata support system, flame proof safety equipment, are exposed to dynamic operational conditions such as stress, humidity, dust, temperature, etc., and safety improvement of such systems can be done preferably during planning and design stage. However, the existing safety analysis methods do not handle the accident initiation and progression of mine systems explicitly. To bridge this gap, this paper presents an integrated Event Tree (ET) and Fault Tree (FT) approach for safety analysis and improvement of mine systems design. This approach includes ET and FT modeling coupled with redundancy allocation technique. In this method, a concept of top hazard probability is introduced for identifying system failure probability and redundancy is allocated to the system either at component or system level. A case study on mine methane explosion safety with two initiating events is performed. The results demonstrate that the presented method can reveal the accident scenarios and improve the safety of complex mine systems simultaneously.

India Renewable Integration Study | Energy Analysis | NREL

Science.gov Websites

India Renewable Integration Study India Renewable Integration Study An NREL grid integration study Energy into India's Electric Grid Vol. I-National Study and Vol. II-Regional Study resolves many system modeling, the study explored operational impacts of meeting India's 2022 targets and identified

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kanna, T.; Sakkaravarthi, K.; Kumar, C. Senthil

In this paper, we have studied the integrability nature of a system of three-coupled Gross-Pitaevskii type nonlinear evolution equations arising in the context of spinor Bose-Einstein condensates by applying the Painleve singularity structure analysis. We show that only for two sets of parametric choices, corresponding to the known integrable cases, the system passes the Painleve test.

Soils and water [Chapter 18

Treesearch

Goran Berndes; Heather Youngs; Maria Victoria Ramos Ballester; Heitor Cantarella; Annette L. Cowie; Graham Jewitt; Luiz Antonio Martinelli; Dan Neary

2015-01-01

Bioenergy production can have positive or negative impacts on soil and water. To best understand these impacts, the effects of bioenergy systems on water and soil resources should be assessed as part of an integrated analysis considering environmental, social and economic dimensions. Bioenergy production systems that are strategically integrated in the landscape to...

Energy Integrated Lighting-Heating-Cooling System.

ERIC Educational Resources Information Center

Meckler, Gershon; And Others

1964-01-01

Energy balance problems in the design of office buildings are analyzed. Through the use of integrated systems utilizing dual purpose products, a controlled environment with minimum expenditure of energy, equipment and space can be provided. Contents include--(1) office building occupancy loads, (2) office building heating load analysis, (3) office…

An Integrated Ecological Modeling System for Assessing Impacts of Multiple Stressors on Stream and Riverine Ecosystem Services Within River Basins

EPA Science Inventory

We demonstrate a novel, spatially explicit assessment of the current condition of aquatic ecosystem services, with limited sensitivity analysis for the atmospheric contaminant mercury. The Integrated Ecological Modeling System (IEMS) forecasts water quality and quantity, habitat ...

Analysis of methods. [information systems evolution environment

NASA Technical Reports Server (NTRS)

Mayer, Richard J. (Editor); Ackley, Keith A.; Wells, M. Sue; Mayer, Paula S. D.; Blinn, Thomas M.; Decker, Louis P.; Toland, Joel A.; Crump, J. Wesley; Menzel, Christopher P.; Bodenmiller, Charles A.

1991-01-01

Information is one of an organization's most important assets. For this reason the development and maintenance of an integrated information system environment is one of the most important functions within a large organization. The Integrated Information Systems Evolution Environment (IISEE) project has as one of its primary goals a computerized solution to the difficulties involved in the development of integrated information systems. To develop such an environment a thorough understanding of the enterprise's information needs and requirements is of paramount importance. This document is the current release of the research performed by the Integrated Development Support Environment (IDSE) Research Team in support of the IISEE project. Research indicates that an integral part of any information system environment would be multiple modeling methods to support the management of the organization's information. Automated tool support for these methods is necessary to facilitate their use in an integrated environment. An integrated environment makes it necessary to maintain an integrated database which contains the different kinds of models developed under the various methodologies. In addition, to speed the process of development of models, a procedure or technique is needed to allow automatic translation from one methodology's representation to another while maintaining the integrity of both. The purpose for the analysis of the modeling methods included in this document is to examine these methods with the goal being to include them in an integrated development support environment. To accomplish this and to develop a method for allowing intra-methodology and inter-methodology model element reuse, a thorough understanding of multiple modeling methodologies is necessary. Currently the IDSE Research Team is investigating the family of Integrated Computer Aided Manufacturing (ICAM) DEFinition (IDEF) languages IDEF(0), IDEF(1), and IDEF(1x), as well as ENALIM, Entity Relationship, Data Flow Diagrams, and Structure Charts, for inclusion in an integrated development support environment.

Optical system design, analysis, and production; Proceedings of the Meeting, Geneva, Switzerland, April 19-22, 1983

NASA Astrophysics Data System (ADS)

Rogers, P. J.; Fischer, R. E.

1983-01-01

Topics considered include: optical system requirements, analysis, and system engineering; optical system design using microcomputers and minicomputers; optical design theory and computer programs; optical design methods and computer programs; optical design methods and philosophy; unconventional optical design; diffractive and gradient index optical system design; optical production and system integration; and optical systems engineering. Particular attention is given to: stray light control as an integral part of optical design; current and future directions of lens design software; thin-film technology in the design and production of optical systems; aspherical lenses in optical scanning systems; the application of volume phase holograms to avionic displays; the effect of lens defects on thermal imager performance; and a wide angle zoom for the Space Shuttle.

Current systematic carbon-cycle observations and the need for implementing a policy-relevant carbon observing system

Treesearch

P. Ciais; A. J. Dolman; A. Bombelli; R. Duren; A. Peregon; P. J. Rayner; C. Miller; N. Gobron; G. Kinderman; G. Marland; N. Gruber; F. Chevallier; R. J. Andres; G. Balsamo; L. Bopp; F.-M. Bréon; G. Broquet; R. Dargaville; T. J. Battin; A. Borges; H. Bovensmann; M. Buchwitz; J. Butler; J. G. Canadell; R. B. Cook; R. DeFries; R. Engelen; K. R. Gurney; C. Heinze; M. Heimann; A. Held; M. Henry; B. Law; S. Luyssaert; J. Miller; T. Moriyama; C. Moulin; R. B. Myneni; C. Nussli; M. Obersteiner; D. Ojima; Y. Pan; J.-D. Paris; S. L. Piao; B. Poulter; S. Plummer; S. Quegan; P. Raymond; M. Reichstein; L. Rivier; C. Sabine; D. Schimel; O. Tarasova; R. Valentini; R. Wang; G. van der Werf; D. Wickland; M. Williams; C. Zehner

2014-01-01

A globally integrated carbon observation and analysis system is needed to improve the fundamental understanding of the global carbon cycle, to improve our ability to project future changes, and to verify the effectiveness of policies aiming to reduce greenhouse gas emissions and increase carbon sequestration. Building an integrated carbon observation system requires...

Integrated Application of Active Controls (IAAC) technology to an advanced subsonic transport project: Current and advanced act control system definition study. Volume 2: Appendices

NASA Technical Reports Server (NTRS)

Hanks, G. W.; Shomber, H. A.; Dethman, H. A.; Gratzer, L. B.; Maeshiro, A.; Gangsaas, D.; Blight, J. D.; Buchan, S. M.; Crumb, C. B.; Dorwart, R. J.

1981-01-01

The current status of the Active Controls Technology (ACT) for the advanced subsonic transport project is investigated through analysis of the systems technical data. Control systems technologies under examination include computerized reliability analysis, pitch axis fly by wire actuator, flaperon actuation system design trade study, control law synthesis and analysis, flutter mode control and gust load alleviation analysis, and implementation of alternative ACT systems. Extensive analysis of the computer techniques involved in each system is included.

CONDUIT: A New Multidisciplinary Integration Environment for Flight Control Development

NASA Technical Reports Server (NTRS)

Tischler, Mark B.; Colbourne, Jason D.; Morel, Mark R.; Biezad, Daniel J.; Levine, William S.; Moldoveanu, Veronica

1997-01-01

A state-of-the-art computational facility for aircraft flight control design, evaluation, and integration called CONDUIT (Control Designer's Unified Interface) has been developed. This paper describes the CONDUIT tool and case study applications to complex rotary- and fixed-wing fly-by-wire flight control problems. Control system analysis and design optimization methods are presented, including definition of design specifications and system models within CONDUIT, and the multi-objective function optimization (CONSOL-OPTCAD) used to tune the selected design parameters. Design examples are based on flight test programs for which extensive data are available for validation. CONDUIT is used to analyze baseline control laws against pertinent military handling qualities and control system specifications. In both case studies, CONDUIT successfully exploits trade-offs between forward loop and feedback dynamics to significantly improve the expected handling, qualities and minimize the required actuator authority. The CONDUIT system provides a new environment for integrated control system analysis and design, and has potential for significantly reducing the time and cost of control system flight test optimization.

Integration of Engine, Plume, and CFD Analyses in Conceptual Design of Low-Boom Supersonic Aircraft

NASA Technical Reports Server (NTRS)

Li, Wu; Campbell, Richard; Geiselhart, Karl; Shields, Elwood; Nayani, Sudheer; Shenoy, Rajiv

2009-01-01

This paper documents an integration of engine, plume, and computational fluid dynamics (CFD) analyses in the conceptual design of low-boom supersonic aircraft, using a variable fidelity approach. In particular, the Numerical Propulsion Simulation System (NPSS) is used for propulsion system cycle analysis and nacelle outer mold line definition, and a low-fidelity plume model is developed for plume shape prediction based on NPSS engine data and nacelle geometry. This model provides a capability for the conceptual design of low-boom supersonic aircraft that accounts for plume effects. Then a newly developed process for automated CFD analysis is presented for CFD-based plume and boom analyses of the conceptual geometry. Five test cases are used to demonstrate the integrated engine, plume, and CFD analysis process based on a variable fidelity approach, as well as the feasibility of the automated CFD plume and boom analysis capability.

An optimal policy for a single-vendor and a single-buyer integrated system with setup cost reduction and process-quality improvement

NASA Astrophysics Data System (ADS)

Shu, Hui; Zhou, Xideng

2014-05-01

The single-vendor single-buyer integrated production inventory system has been an object of study for a long time, but little is known about the effect of investing in reducing setup cost reduction and process-quality improvement for an integrated inventory system in which the products are sold with free minimal repair warranty. The purpose of this article is to minimise the integrated cost by optimising simultaneously the number of shipments and the shipment quantity, the setup cost, and the process quality. An efficient algorithm procedure is proposed for determining the optimal decision variables. A numerical example is presented to illustrate the results of the proposed models graphically. Sensitivity analysis of the model with respect to key parameters of the system is carried out. The paper shows that the proposed integrated model can result in significant savings in the integrated cost.

Integrated modeling environment for systems-level performance analysis of the Next-Generation Space Telescope

NASA Astrophysics Data System (ADS)

Mosier, Gary E.; Femiano, Michael; Ha, Kong; Bely, Pierre Y.; Burg, Richard; Redding, David C.; Kissil, Andrew; Rakoczy, John; Craig, Larry

1998-08-01

All current concepts for the NGST are innovative designs which present unique systems-level challenges. The goals are to outperform existing observatories at a fraction of the current price/performance ratio. Standard practices for developing systems error budgets, such as the 'root-sum-of- squares' error tree, are insufficient for designs of this complexity. Simulation and optimization are the tools needed for this project; in particular tools that integrate controls, optics, thermal and structural analysis, and design optimization. This paper describes such an environment which allows sub-system performance specifications to be analyzed parametrically, and includes optimizing metrics that capture the science requirements. The resulting systems-level design trades are greatly facilitated, and significant cost savings can be realized. This modeling environment, built around a tightly integrated combination of commercial off-the-shelf and in-house- developed codes, provides the foundation for linear and non- linear analysis on both the time and frequency-domains, statistical analysis, and design optimization. It features an interactive user interface and integrated graphics that allow highly-effective, real-time work to be done by multidisciplinary design teams. For the NGST, it has been applied to issues such as pointing control, dynamic isolation of spacecraft disturbances, wavefront sensing and control, on-orbit thermal stability of the optics, and development of systems-level error budgets. In this paper, results are presented from parametric trade studies that assess requirements for pointing control, structural dynamics, reaction wheel dynamic disturbances, and vibration isolation. These studies attempt to define requirements bounds such that the resulting design is optimized at the systems level, without attempting to optimize each subsystem individually. The performance metrics are defined in terms of image quality, specifically centroiding error and RMS wavefront error, which directly links to science requirements.

Human Support Technology Research to Enable Exploration

NASA Technical Reports Server (NTRS)

Joshi, Jitendra

2003-01-01

Contents include the following: Advanced life support. System integration, modeling, and analysis. Progressive capabilities. Water processing. Air revitalization systems. Why advanced CO2 removal technology? Solid waste resource recovery systems: lyophilization. ISRU technologies for Mars life support. Atmospheric resources of Mars. N2 consumable/make-up for Mars life. Integrated test beds. Monitoring and controlling the environment. Ground-based commercial technology. Optimizing size vs capability. Water recovery systems. Flight verification topics.

Using social network and stakeholder analysis to help evaluate infectious waste management: A step towards a holistic assessment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Caniato, Marco, E-mail: marcocaniato@gmail.com; Vaccari, Mentore, E-mail: mentore.vaccari@unibs.it; Visvanathan, Chettiyappan, E-mail: visu@ait.ac.th

Highlights: • Assessment of infectious waste management in Bangkok, in particular incineration. • Integration of social network and stakeholder analysis assessment methods. • Assessment of stakeholder characteristics, role, interaction and communication. • Interviewees self-evaluate their own characteristics and the system. • Non-technical aspects are important for system acceptability, and sustainability. - Abstract: Assessing the strengths and weaknesses of a solid waste management scheme requires an accurate analysis and integration of several determining features. In addition to the technical aspects, any such system shows a complex interaction of actors with varying stakes, decision-making power and influence, as well as a favourablemore » or disabling environment. When capitalizing on the knowledge and experience from a specific case, it is also crucial that experts do not “forget” or underestimate the importance of such social determinants and that they are familiar with the methods and tools to assess them. Social network analysis (SNA) and stakeholder analysis (SA) methods can be successfully applied to better understand actors’ role and actions, analyse driving forces and existing coordination among stakeholders, as well as identify bottlenecks in communication which affect daily operations or strategic planning for the future way forward. SNA and SA, appropriately adjusted for a certain system, can provide a useful integration to methods by assessing other aspects to ensure a comprehensive picture of the situation. This paper describes how to integrate SNA and SA in order to survey a solid waste management system. This paper presents the results of an analysis of On-Nuch infectious waste incinerator in Bangkok, Thailand. Stakeholders were interviewed and asked to prioritize characteristics and relationships which they consider particularly important for system development and success of the scheme. In such a way, a large quantity of information about organization, communication between stakeholders and their perception about operation, environmental and health impact, and potential alternatives for the system was collected in a systematic way. The survey results suggest that stakeholders are generally satisfied with the system operation, though communication should be improved. Moreover, stakeholders should be strategically more involved in system development planning, according to their characteristics, to prevent negative reactions.« less

Cyber Contingency Analysis version 1.x

DOE Office of Scientific and Technical Information (OSTI.GOV)

Contingency analysis based approach for quantifying and examining the resiliency of a cyber system in respect to confidentiality, integrity and availability. A graph representing an organization's cyber system and related resources is used for the availability contingency analysis. The mission critical paths associated with an organization are used to determine the consequences of a potential contingency. A node (or combination of nodes) are removed from the graph to analyze a particular contingency. The value of all mission critical paths that are disrupted by that contingency are used to quantify its severity. A total severity score can be calculated based onmore » the complete list of all these contingencies. A simple n1 analysis can be done in which only one node is removed at a time for the analysis. We can also compute nk analysis, where k is the number of nodes to simultaneously remove for analysis. A contingency risk score can also be computed, which takes the probability of the contingencies into account. In addition to availability, we can also quantify confidentiality and integrity scores for the system. These treat user accounts as potential contingencies. The amount (and type) of files that an account can read to is used to compute the confidentiality score. The amount (and type) of files that an account can write to is used to compute the integrity score. As with availability analysis, we can use this information to compute total severity scores in regards to confidentiality and integrity. We can also take probability into account to compute associated risk scores.« less

Integrated versus nOn-integrated Peripheral inTravenous catheter. Which Is the most effective systeM for peripheral intravenoUs catheter Management? (The OPTIMUM study): a randomised controlled trial protocol

PubMed Central

Castillo, Maria Isabel; Larsen, Emily; Cooke, Marie; Marsh, Nicole M; Wallis, Marianne C; Finucane, Julie; Brown, Peter; Mihala, Gabor; Byrnes, Joshua; Walker, Rachel; Cable, Prudence; Zhang, Li; Sear, Candi; Jackson, Gavin; Rowsome, Anna; Ryan, Alison; Humphries, Julie C; Sivyer, Susan; Flanigan, Kathy; Rickard, Claire M

2018-01-01

Introduction Peripheral intravenous catheters (PIVCs) are frequently used in hospitals. However, PIVC complications are common, with failures leading to treatment delays, additional procedures, patient pain and discomfort, increased clinician workload and substantially increased healthcare costs. Recent evidence suggests integrated PIVC systems may be more effective than traditional non-integrated PIVC systems in reducing phlebitis, infiltration and costs and increasing functional dwell time. The study aim is to determine the efficacy, cost–utility and acceptability to patients and professionals of an integrated PIVC system compared with a non-integrated PIVC system. Methods and analysis Two-arm, multicentre, randomised controlled superiority trial of integrated versus non-integrated PIVC systems to compare effectiveness on clinical and economic outcomes. Recruitment of 1560 patients over 2 years, with randomisation by a centralised service ensuring allocation concealment. Primary outcomes: catheter failure (composite endpoint) for reasons of: occlusion, infiltration/extravasation, phlebitis/thrombophlebitis, dislodgement, localised or catheter-associated bloodstream infections. Secondary outcomes: first time insertion success, types of PIVC failure, device colonisation, insertion pain, functional dwell time, adverse events, mortality, cost–utility and consumer acceptability. One PIVC per patient will be included, with intention-to-treat analysis. Baseline group comparisons will be made for potentially clinically important confounders. The proportional hazards assumption will be checked, and Cox regression will test the effect of group, patient, device and clinical variables on failure. An as-treated analysis will assess the effect of protocol violations. Kaplan-Meier survival curves with log-rank tests will compare failure by group over time. Secondary endpoints will be compared between groups using parametric/non-parametric techniques. Ethics and dissemination Ethical approval from the Royal Brisbane and Women’s Hospital Human Research Ethics Committee (HREC/16/QRBW/527), Griffith University Human Research Ethics Committee (Ref No. 2017/002) and the South Metropolitan Health Services Human Research Ethics Committee (Ref No. 2016–239). Results will be published in peer-reviewed journals. Trial registration number ACTRN12617000089336. PMID:29764876

Metrics for Analyzing Quantifiable Differentiation of Designs with Varying Integrity for Hardware Assurance

DTIC Science & Technology

2017-03-01

proposed. Expected profiles can incorporate a level of overdesign. Finally, the Design Integrity measuring techniques are applied to five Test Article ...Inserted into Test System Table 2 presents the results of the analysis applied to each of the test article designs. Each of the domains are...the lowest integrities. Based on the analysis, the DI metric shows measurable differentiation between all five Test Article Error Location Error

Computational singular perturbation analysis of stochastic chemical systems with stiffness

NASA Astrophysics Data System (ADS)

Wang, Lijin; Han, Xiaoying; Cao, Yanzhao; Najm, Habib N.

2017-04-01

Computational singular perturbation (CSP) is a useful method for analysis, reduction, and time integration of stiff ordinary differential equation systems. It has found dominant utility, in particular, in chemical reaction systems with a large range of time scales at continuum and deterministic level. On the other hand, CSP is not directly applicable to chemical reaction systems at micro or meso-scale, where stochasticity plays an non-negligible role and thus has to be taken into account. In this work we develop a novel stochastic computational singular perturbation (SCSP) analysis and time integration framework, and associated algorithm, that can be used to not only construct accurately and efficiently the numerical solutions to stiff stochastic chemical reaction systems, but also analyze the dynamics of the reduced stochastic reaction systems. The algorithm is illustrated by an application to a benchmark stochastic differential equation model, and numerical experiments are carried out to demonstrate the effectiveness of the construction.

The integrated analysis capability (IAC Level 2.0)

NASA Technical Reports Server (NTRS)

Frisch, Harold P.; Vos, Robert G.

1988-01-01

The critical data management issues involved in the development of the integral analysis capability (IAC), Level 2, to support the design analysis and performance evaluation of large space structures, are examined. In particular, attention is given to the advantages and disadvantages of the formalized data base; merging of the matrix and relational data concepts; data types, query operators, and data handling; sequential versus direct-access files; local versus global data access; programming languages and host machines; and data flow techniques. The discussion also covers system architecture, recent system level enhancements, executive/user interface capabilities, and technology applications.

A Microwave Photonic Interference Canceller: Architectures, Systems, and Integration

NASA Astrophysics Data System (ADS)

Chang, Matthew P.

This thesis is a comprehensive portfolio of work on a Microwave Photonic Self-Interference Canceller (MPC), a specialized optical system designed to eliminate interference from radio-frequency (RF) receivers. The novelty and value of the microwave photonic system lies in its ability to operate over bandwidths and frequencies that are orders of magnitude larger than what is possible using existing RF technology. The work begins, in 2012, with a discrete fiber-optic microwave photonic canceller, which prior work had demonstrated as a proof-of-concept, and culminates, in 2017, with the first ever monolithically integrated microwave photonic canceller. With an eye towards practical implementation, the thesis establishes novelty through three major project thrusts. (Fig. 1): (1) Extensive RF and system analysis to develop a full understanding of how, and through what mechanisms, MPCs affect an RF receiver. The first investigations of how a microwave photonic canceller performs in an actual wireless environment and a digital radio are also presented. (2) New architectures to improve the performance and functionality of MPCs, based on the analysis performed in Thrust 1. A novel balanced microwave photonic canceller architecture is developed and experimentally demonstrated. The balanced architecture shows significant improvements in link gain, noise figure, and dynamic range. Its main advantage is its ability to suppress common-mode noise and reduce noise figure by increasing the optical power. (3) Monolithic integration of the microwave photonic canceller into a photonic integrated circuit. This thrust presents the progression of integrating individual discrete devices into their semiconductor equivalent, as well as a full functional and RF analysis of the first ever integrated microwave photonic canceller.

Controls-Structures Interaction (CSI) technology program summary. Earth orbiting platforms program area of the space platforms technology program

NASA Technical Reports Server (NTRS)

Newsom, Jerry R.

1991-01-01

Control-Structures Interaction (CSI) technology embraces the understanding of the interaction between the spacecraft structure and the control system, and the creation and validation of concepts, techniques, and tools, for enabling the interdisciplinary design of an integrated structure and control system, rather than the integration of a structural design and a control system design. The goal of this program is to develop validated CSI technology for integrated design/analysis and qualification of large flexible space systems and precision space structures. A description of the CSI technology program is presented.

A Prototyping Effort for the Integrated Spacecraft Analysis System

NASA Technical Reports Server (NTRS)

Wong, Raymond; Tung, Yu-Wen; Maldague, Pierre

2011-01-01

Computer modeling and simulation has recently become an essential technique for predicting and validating spacecraft performance. However, most computer models only examine spacecraft subsystems, and the independent nature of the models creates integration problems, which lowers the possibilities of simulating a spacecraft as an integrated unit despite a desire for this type of analysis. A new project called Integrated Spacecraft Analysis was proposed to serve as a framework for an integrated simulation environment. The project is still in its infancy, but a software prototype would help future developers assess design issues. The prototype explores a service oriented design paradigm that theoretically allows programs written in different languages to communicate with one another. It includes creating a uniform interface to the SPICE libraries such that different in-house tools like APGEN or SEQGEN can exchange information with it without much change. Service orientation may result in a slower system as compared to a single application, and more research needs to be done on the different available technologies, but a service oriented approach could increase long term maintainability and extensibility.

Perceiving integration of a complementary medicine service within a general surgery department through documentation of consultations: a thematic analysis.

PubMed

Schiff, Elad; Ben-Arye, Eran; Attias, Samuel; Sroka, Gideon; Matter, Ibrahim; Keshet, Yael

2012-12-01

This study aims to examine the meaning and practical implications of integration of a complementary medicine-based surgery service in a hospital setting (CISS--Complementary/Integrative Surgery Service) through analysis of consultation reports associated with this service. Thematic analysis was used to evaluate CISS consultation reports in a hospital electronic consultant charting system during the first half year of the service's activity. 304 consultation reports were analyzed. Nurses initiated significantly more consultations than physicians (55% vs 7%). Consultation requests were gradually more focused on specific symptoms, possibly manifesting a better understanding of the scope of complementary medicine in the surgery setting. CISS practitioners responded in more biomedical language over time, albeit offering a more holistic perspective regarding patients' needs as well as clarifications regarding the nature of the treatment they provided. Diverse communication patterns in consultations evolved over time representing dynamics in multiple levels of integration of the CISS. Documented communication through consultations can provide a window to the process of integration of complementary medicine-based services in health systems. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

NASTRAN applications to aircraft propulsion systems

NASA Technical Reports Server (NTRS)

White, J. L.; Beste, D. L.

1975-01-01

The use of NASTRAN in propulsion system structural integration analysis is described. Computer support programs for modeling, substructuring, and plotting analysis results are discussed. Requirements on interface information and data exchange by participants in a NASTRAN substructure analysis are given. Static and normal modes vibration analysis results are given with comparison to test and other analytical results.

Exploration Life Support Critical Questions for Future Human Space Missions

NASA Technical Reports Server (NTRS)

Kwert, Michael K.; Barta, Daniel J.; McQuillan, Jeff

2010-01-01

Exploration Life Support (ELS) is a current project under NASA's Exploration Systems Mission Directorate. The ELS Project plans, coordinates and implements the development of advanced life support technologies for human exploration missions in space. Recent work has focused on closed loop atmosphere and water systems for long duration missions, including habitats and pressurized rovers. But, what are the critical questions facing life support system developers for these and other future human missions? This paper explores those questions and how progress in the development of ELS technologies can help answer them. The ELS Project includes the following Elements: Atmosphere Revitalization Systems, Water Recovery Systems, Waste Management Systems, Habitation Engineering, Systems Integration, Modeling and Analysis, and Validation and Testing, which includes the Sub-Elements Flight Experiments and Integrated Testing. Systems engineering analysis by ELS seeks to optimize overall mission architectures by considering all the internal and external interfaces of the life support system and the potential for reduction or reuse of commodities. In particular, various sources and sinks of water and oxygen are considered along with the implications on loop closure and the resulting launch mass requirements. Systems analysis will be validated through the data gathered from integrated testing, which will demonstrate the interfaces of a closed loop life support system. By applying a systematic process for defining, sorting and answering critical life support questions, the ELS project is preparing for a variety of future human space missions

Integrated Design Engineering Analysis (IDEA) Environment - Aerodynamics, Aerothermodynamics, and Thermal Protection System Integration Module

NASA Technical Reports Server (NTRS)

Kamhawi, Hilmi N.

2011-01-01

This report documents the work performed during from March 2010 October 2011. The Integrated Design and Engineering Analysis (IDEA) environment is a collaborative environment based on an object-oriented, multidisciplinary, distributed environment using the Adaptive Modeling Language (AML) as the underlying framework. This report will focus on describing the work done in the area of extending the aerodynamics, and aerothermodynamics module using S/HABP, CBAERO, PREMIN and LANMIN. It will also detail the work done integrating EXITS as the TPS sizing tool.

Analysis methods for wind turbine control and electrical system dynamics

NASA Technical Reports Server (NTRS)

Hinrichsen, E. N.

1995-01-01

The integration of new energy technologies into electric power systems requires methods which recognize the full range of dynamic events in both the new generating unit and the power system. Since new energy technologies are initially perceived as small contributors to large systems, little attention is generally paid to system integration, i.e. dynamic events in the power system are ignored. As a result, most new energy sources are only capable of base-load operation, i.e. they have no load following or cycling capability. Wind turbines are no exception. Greater awareness of this implicit (and often unnecessary) limitation is needed. Analysis methods are recommended which include very low penetration (infinite bus) as well as very high penetration (stand-alone) scenarios.

Human System Integration: Regulatory Analysis

NASA Technical Reports Server (NTRS)

2005-01-01

This document was intended as an input to the Access 5 Policy Integrated Product team. Using a Human System Integration (HIS) perspective, a regulatory analyses of the FARS (specifically Part 91), the Airman s Information Manual (AIM) and the FAA Controllers Handbook (7110.65) was conducted as part of a front-end approach needed to derive HSI requirements for Unmanned Aircraft Systems (UAS) operations in the National Airspace System above FL430. The review of the above aviation reference materials yielded eighty-four functions determined to be necessary or highly desirable for flight within the Air Traffic Management System. They include categories for Flight, Communications, Navigation, Surveillance, and Hazard Avoidance.

Multi-disciplinary coupling effects for integrated design of propulsion systems

NASA Technical Reports Server (NTRS)

Chamis, C. C.; Singhal, S. N.

1993-01-01

Effective computational simulation procedures are described for modeling the inherent multi-disciplinary interactions which govern the accurate response of propulsion systems. Results are presented for propulsion system responses including multi-disciplinary coupling effects using coupled multi-discipline thermal, structural, and acoustic tailoring; an integrated system of multi-disciplinary simulators; coupled material behavior/fabrication process tailoring; sensitivities using a probabilistic simulator; and coupled materials, structures, fracture, and probabilistic behavior simulator. The results demonstrate that superior designs can be achieved if the analysis/tailoring methods account for the multi-disciplinary coupling effects. The coupling across disciplines can be used to develop an integrated coupled multi-discipline numerical propulsion system simulator.

Multi-disciplinary coupling for integrated design of propulsion systems

NASA Technical Reports Server (NTRS)

Chamis, C. C.; Singhal, S. N.

1993-01-01

Effective computational simulation procedures are described for modeling the inherent multi-disciplinary interactions for determining the true response of propulsion systems. Results are presented for propulsion system responses including multi-discipline coupling effects via (1) coupled multi-discipline tailoring, (2) an integrated system of multidisciplinary simulators, (3) coupled material-behavior/fabrication-process tailoring, (4) sensitivities using a probabilistic simulator, and (5) coupled materials/structures/fracture/probabilistic behavior simulator. The results show that the best designs can be determined if the analysis/tailoring methods account for the multi-disciplinary coupling effects. The coupling across disciplines can be used to develop an integrated interactive multi-discipline numerical propulsion system simulator.

Stability Analysis of the Planetary System Orbiting Upsilon Andromedae

NASA Technical Reports Server (NTRS)

Lissauer, Jack J.; Rivera, Eugenio J.; DeVincenzi, Donald (Technical Monitor)

2000-01-01

We present results of long-term numerical orbital integrations designed to test the stability of the three-planet system orbiting Upsilon Andromedae and short-term integrations to test whether mutual perturbations among the planets can be used to determine planetary masses. Our initial conditions are based on the latest fits to the radial velocity data obtained by the planet-search group at Lick Observatory. The new fits result in significantly more stable systems than did the initially announced planetary parameters. An analytic analysis of the star and the two outer planets shows that this subsystem is Hill stable up to five. Our integrations involving all three planets show that the system is stable for at least 100 Myr for up to four. In our simulations, we still see a secular resonance between the outer two planets and in some cases large oscillations in the eccentricity of the inner planet.

Propulsion System Airframe Integration Issues and Aerodynamic Database Development for the Hyper-X Flight Research Vehicle

NASA Technical Reports Server (NTRS)

Engelund, Walter C.; Holland, Scott D.; Cockrell, Charles E., Jr.; Bittner, Robert D.

1999-01-01

NASA's Hyper-X Research Vehicle will provide a unique opportunity to obtain data on an operational airframe integrated scramjet propulsion system at true flight conditions. The airframe integrated nature of the scramjet engine with the Hyper-X vehicle results in a strong coupling effect between the propulsion system operation and the airframe s basic aerodynamic characteristics. Comments on general airframe integrated scramjet propulsion system effects on vehicle aerodynamic performance, stability, and control are provided, followed by examples specific to the Hyper-X research vehicle. An overview is provided of the current activities associated with the development of the Hyper-X aerodynamic database, including wind tunnel test activities and parallel CFD analysis efforts. A brief summary of the Hyper-X aerodynamic characteristics is provided, including the direct and indirect effects of the airframe integrated scramjet propulsion system operation on the basic airframe stability and control characteristics.

Model-based engineering for laser weapons systems

NASA Astrophysics Data System (ADS)

Panthaki, Malcolm; Coy, Steve

2011-10-01

The Comet Performance Engineering Workspace is an environment that enables integrated, multidisciplinary modeling and design/simulation process automation. One of the many multi-disciplinary applications of the Comet Workspace is for the integrated Structural, Thermal, Optical Performance (STOP) analysis of complex, multi-disciplinary space systems containing Electro-Optical (EO) sensors such as those which are designed and developed by and for NASA and the Department of Defense. The CometTM software is currently able to integrate performance simulation data and processes from a wide range of 3-D CAD and analysis software programs including CODE VTM from Optical Research Associates and SigFitTM from Sigmadyne Inc. which are used to simulate the optics performance of EO sensor systems in space-borne applications. Over the past year, Comet Solutions has been working with MZA Associates of Albuquerque, NM, under a contract with the Air Force Research Laboratories. This funded effort is a "risk reduction effort", to help determine whether the combination of Comet and WaveTrainTM, a wave optics systems engineering analysis environment developed and maintained by MZA Associates and used by the Air Force Research Laboratory, will result in an effective Model-Based Engineering (MBE) environment for the analysis and design of laser weapons systems. This paper will review the results of this effort and future steps.

Evolution of the Tropical Cyclone Integrated Data Exchange And Analysis System (TC-IDEAS)

NASA Technical Reports Server (NTRS)

Turk, J.; Chao, Y.; Haddad, Z.; Hristova-Veleva, S.; Knosp, B.; Lambrigtsen, B.; Li, P.; Licata, S.; Poulsen, W.; Su, H.;

The Environment for Application Software Integration and Execution (EASIE), version 1.0. Volume 2: Program integration guide

NASA Technical Reports Server (NTRS)

Jones, Kennie H.; Randall, Donald P.; Stallcup, Scott S.; Rowell, Lawrence F.

1988-01-01

The Environment for Application Software Integration and Execution, EASIE, provides a methodology and a set of software utility programs to ease the task of coordinating engineering design and analysis codes. EASIE was designed to meet the needs of conceptual design engineers that face the task of integrating many stand-alone engineering analysis programs. Using EASIE, programs are integrated through a relational data base management system. In volume 2, the use of a SYSTEM LIBRARY PROCESSOR is used to construct a DATA DICTIONARY describing all relations defined in the data base, and a TEMPLATE LIBRARY. A TEMPLATE is a description of all subsets of relations (including conditional selection criteria and sorting specifications) to be accessed as input or output for a given application. Together, these form the SYSTEM LIBRARY which is used to automatically produce the data base schema, FORTRAN subroutines to retrieve/store data from/to the data base, and instructions to a generic REVIEWER program providing review/modification of data for a given template. Automation of these functions eliminates much of the tedious, error prone work required by the usual approach to data base integration.

Integration of design and inspection

NASA Astrophysics Data System (ADS)

Simmonds, William H.

1990-08-01

Developments in advanced computer integrated manufacturing technology, coupled with the emphasis on Total Quality Management, are exposing needs for new techniques to integrate all functions from design through to support of the delivered product. One critical functional area that must be integrated into design is that embracing the measurement, inspection and test activities necessary for validation of the delivered product. This area is being tackled by a collaborative project supported by the UK Government Department of Trade and Industry. The project is aimed at developing techniques for analysing validation needs and for planning validation methods. Within the project an experimental Computer Aided Validation Expert system (CAVE) is being constructed. This operates with a generalised model of the validation process and helps with all design stages: specification of product requirements; analysis of the assurance provided by a proposed design and method of manufacture; development of the inspection and test strategy; and analysis of feedback data. The kernel of the system is a knowledge base containing knowledge of the manufacturing process capabilities and of the available inspection and test facilities. The CAVE system is being integrated into a real life advanced computer integrated manufacturing facility for demonstration and evaluation.

Energy efficient engine. Volume 1: Component development and integration program

NASA Technical Reports Server (NTRS)

1981-01-01

Technology for achieving lower installed fuel consumption and lower operating costs in future commercial turbofan engines are developed, evaluated, and demonstrated. The four program objectives are: (1) propulsion system analysis; (2) component analysis, design, and development; (3) core design, fabrication, and test; and (4) integrated core/low spoon design, fabrication, and test.

Barriers to Successful Implementation of Technology Integration in Educational Settings: A Case Study

ERIC Educational Resources Information Center

Laferrière, T.; Hamel, C.; Searson, M.

2013-01-01

Representing issues discussed at the EduSummIT 2011 relative to essential conditions and barriers to successful technology integration, this article presents a systemic analysis of barriers that needed to be overcome for an information technology initiative (Remote Networked School project) to be successfully implemented. The analysis was…

Measuring Integration of Cancer Services to Support Performance Improvement: The CSI Survey

PubMed Central

Dobrow, Mark J.; Paszat, Lawrence; Golden, Brian; Brown, Adalsteinn D.; Holowaty, Eric; Orchard, Margo C.; Monga, Neerav; Sullivan, Terrence

2009-01-01

Objective: To develop a measure of cancer services integration (CSI) that can inform clinical and administrative decision-makers in their efforts to monitor and improve cancer system performance. Methods: We employed a systematic approach to measurement development, including review of existing cancer/health services integration measures, key-informant interviews and focus groups with cancer system leaders. The research team constructed a Web-based survey that was field- and pilot-tested, refined and then formally conducted on a sample of cancer care providers and administrators in Ontario, Canada. We then conducted exploratory factor analysis to identify key dimensions of CSI. Results: A total of 1,769 physicians, other clinicians and administrators participated in the survey, responding to a 67-item questionnaire. The exploratory factor analysis identified 12 factors that were linked to three broader dimensions: clinical, functional and vertical system integration. Conclusions: The CSI Survey provides important insights on a range of typically unmeasured aspects of the coordination and integration of cancer services, representing a new tool to inform performance improvement efforts. PMID:20676250

Integrative Analysis of Omics Big Data.

PubMed

Yu, Xiang-Tian; Zeng, Tao

2018-01-01

The diversity and huge omics data take biology and biomedicine research and application into a big data era, just like that popular in human society a decade ago. They are opening a new challenge from horizontal data ensemble (e.g., the similar types of data collected from different labs or companies) to vertical data ensemble (e.g., the different types of data collected for a group of person with match information), which requires the integrative analysis in biology and biomedicine and also asks for emergent development of data integration to address the great changes from previous population-guided to newly individual-guided investigations.Data integration is an effective concept to solve the complex problem or understand the complicate system. Several benchmark studies have revealed the heterogeneity and trade-off that existed in the analysis of omics data. Integrative analysis can combine and investigate many datasets in a cost-effective reproducible way. Current integration approaches on biological data have two modes: one is "bottom-up integration" mode with follow-up manual integration, and the other one is "top-down integration" mode with follow-up in silico integration.This paper will firstly summarize the combinatory analysis approaches to give candidate protocol on biological experiment design for effectively integrative study on genomics and then survey the data fusion approaches to give helpful instruction on computational model development for biological significance detection, which have also provided newly data resources and analysis tools to support the precision medicine dependent on the big biomedical data. Finally, the problems and future directions are highlighted for integrative analysis of omics big data.

Review of Exploration Systems Development (ESD) Integrated Hazard Development Process. Volume 1; Appendices

NASA Technical Reports Server (NTRS)

Smiles, Michael D.; Blythe, Michael P.; Bejmuk, Bohdan; Currie, Nancy J.; Doremus, Robert C.; Franzo, Jennifer C.; Gordon, Mark W.; Johnson, Tracy D.; Kowaleski, Mark M.; Laube, Jeffrey R.

2015-01-01

The Chief Engineer of the Exploration Systems Development (ESD) Office requested that the NASA Engineering and Safety Center (NESC) perform an independent assessment of the ESD's integrated hazard development process. The focus of the assessment was to review the integrated hazard analysis (IHA) process and identify any gaps/improvements in the process (e.g., missed causes, cause tree completeness, missed hazards). This document contains the outcome of the NESC assessment.

Review of Exploration Systems Development (ESD) Integrated Hazard Development Process. Appendices; Volume 2

NASA Technical Reports Server (NTRS)

Smiles, Michael D.; Blythe, Michael P.; Bejmuk, Bohdan; Currie, Nancy J.; Doremus, Robert C.; Franzo, Jennifer C.; Gordon, Mark W.; Johnson, Tracy D.; Kowaleski, Mark M.; Laube, Jeffrey R.

2015-01-01

The Chief Engineer of the Exploration Systems Development (ESD) Office requested that the NASA Engineering and Safety Center (NESC) perform an independent assessment of the ESD's integrated hazard development process. The focus of the assessment was to review the integrated hazard analysis (IHA) process and identify any gaps/improvements in the process (e.g. missed causes, cause tree completeness, missed hazards). This document contains the outcome of the NESC assessment.

Wind Turbine Optimization with WISDEM

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dykes, Katherine L; Damiani, Rick R; Graf, Peter A

This presentation for the Fourth Wind Energy Systems Engineering Workshop explains the NREL wind energy systems engineering initiative-developed analysis platform and research capability to capture important system interactions to achieve a better understanding of how to improve system-level performance and achieve system-level cost reductions. Topics include Wind-Plant Integrated System Design and Engineering Model (WISDEM) and multidisciplinary design analysis and optimization.

Modeling the Value of Integrated Canadian and U.S. Power Sector Expansion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cole, Wesley, Beiter, Philipp; Steinberg, Daniel

2016-09-08

The United States and Canada power systems are not isolated. Cross-border transmission and coordination of system operation create an interconnected power system, which results in combined imports and exports of electricity of greater than 70 TWh per year [1]. Currently, over 5 GW of new international transmission lines are in various stages of permitting and development. These lines may enable greater integration and coordination of the U.S. and Canada systems, which can in turn reduce challenges associated with integration of high penetrations of variable renewables. Furthermore, low-cost Canadian resources, such as wind and hydro, could contribute to compliance with themore » EPA's recently released Clean Power Plan. Improving integration and coordination internationally will reduce the costs of accessing these resources. This analysis work build on previous work by Ibanez and Zinaman [2]. In this work we seek to better understand the value of additional interconnection between the U.S. and Canadian power systems. Specifically, we quantify the value of additional interconnection and coordination within the Canadian-US integrated power system under scenarios in which large reductions (>80%) in power sector CO2 emissions are achieved. We explore how the ability to add additional cross-border transmission impacts capacity investment, the generation mix, system costs, and the ability of the system to integrate variable renewable energy into the power system. This analysis uses the Regional Energy Deployment System (ReEDS) capacity expansion model [3], [4] to quantify the value of the integrated power system expansion of the United States and Canada. ReEDS is an optimization model that assesses the deployment and operation (including transmission) of the electricity sector of the contiguous United States and Canadian provinces from 2016 through 2050. It has the ability to model the integration of renewable energy technologies into the grid. ReEDS captures renewable energy resources through the use of 356 individual resource regions and 134 balancing areas across the U.S. and is able to handle renewable energy issues such as variability in wind and solar output, transmission costs and constraints, and ancillary services requirements.« less

Gene context analysis in the Integrated Microbial Genomes (IMG) data management system.

PubMed

Mavromatis, Konstantinos; Chu, Ken; Ivanova, Natalia; Hooper, Sean D; Markowitz, Victor M; Kyrpides, Nikos C

2009-11-24

Computational methods for determining the function of genes in newly sequenced genomes have been traditionally based on sequence similarity to genes whose function has been identified experimentally. Function prediction methods can be extended using gene context analysis approaches such as examining the conservation of chromosomal gene clusters, gene fusion events and co-occurrence profiles across genomes. Context analysis is based on the observation that functionally related genes are often having similar gene context and relies on the identification of such events across phylogenetically diverse collection of genomes. We have used the data management system of the Integrated Microbial Genomes (IMG) as the framework to implement and explore the power of gene context analysis methods because it provides one of the largest available genome integrations. Visualization and search tools to facilitate gene context analysis have been developed and applied across all publicly available archaeal and bacterial genomes in IMG. These computations are now maintained as part of IMG's regular genome content update cycle. IMG is available at: http://img.jgi.doe.gov.

Impact Assessment of GNSS Spoofing Attacks on INS/GNSS Integrated Navigation System.

PubMed

Liu, Yang; Li, Sihai; Fu, Qiangwen; Liu, Zhenbo

2018-05-04

In the face of emerging Global Navigation Satellite System (GNSS) spoofing attacks, there is a need to give a comprehensive analysis on how the inertial navigation system (INS)/GNSS integrated navigation system responds to different kinds of spoofing attacks. A better understanding of the integrated navigation system’s behavior with spoofed GNSS measurements gives us valuable clues to develop effective spoofing defenses. This paper focuses on an impact assessment of GNSS spoofing attacks on the integrated navigation system Kalman filter’s error covariance, innovation sequence and inertial sensor bias estimation. A simple and straightforward measurement-level trajectory spoofing simulation framework is presented, serving as the basis for an impact assessment of both unsynchronized and synchronized spoofing attacks. Recommendations are given for spoofing detection and mitigation based on our findings in the impact assessment process.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Harris, L.; Owel, W.R.

This paper discusses the VISA (Vulnerability of Integrated Safeguards Analysis) method, developed in 1976-77 for the Nuclear Regulatory Commission, and which has been adapted more recently to a broader range of uses. The performance of VISA systems is evaluated in terms of how they perform as an integrated safeguards/security system. The resulting method has been designated VISA-2. 7 refs.

Investigating the Nexus of Climate, Energy, Water, and Land at Decision-Relevant Scales: The Platform for Regional Integrated Modeling and Analysis (PRIMA)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kraucunas, Ian P.; Clarke, Leon E.; Dirks, James A.

2015-04-01

The Platform for Regional Integrated Modeling and Analysis (PRIMA) is an innovative modeling system developed at Pacific Northwest National Laboratory (PNNL) to simulate interactions among natural and human systems at scales relevant to regional decision making. PRIMA brings together state-of-the-art models of regional climate, hydrology, agriculture, socioeconomics, and energy systems using a flexible coupling approach. The platform can be customized to inform a variety of complex questions and decisions, such as the integrated evaluation of mitigation and adaptation options across a range of sectors. Research into stakeholder decision support needs underpins the platform's application to regional issues, including uncertainty characterization.more » Ongoing numerical experiments are yielding new insights into the interactions among human and natural systems on regional scales with an initial focus on the energy-land-water nexus in the upper U.S. Midwest. This paper focuses on PRIMA’s functional capabilities and describes some lessons learned to date about integrated regional modeling.« less

Social Ecological Model Analysis for ICT Integration

ERIC Educational Resources Information Center

Zagami, Jason

2013-01-01

ICT integration of teacher preparation programmes was undertaken by the Australian Teaching Teachers for the Future (TTF) project in all 39 Australian teacher education institutions and highlighted the need for guidelines to inform systemic ICT integration approaches. A Social Ecological Model (SEM) was used to positively inform integration…

Systems Toxicology: From Basic Research to Risk Assessment

PubMed Central

2014-01-01

Systems Toxicology is the integration of classical toxicology with quantitative analysis of large networks of molecular and functional changes occurring across multiple levels of biological organization. Society demands increasingly close scrutiny of the potential health risks associated with exposure to chemicals present in our everyday life, leading to an increasing need for more predictive and accurate risk-assessment approaches. Developing such approaches requires a detailed mechanistic understanding of the ways in which xenobiotic substances perturb biological systems and lead to adverse outcomes. Thus, Systems Toxicology approaches offer modern strategies for gaining such mechanistic knowledge by combining advanced analytical and computational tools. Furthermore, Systems Toxicology is a means for the identification and application of biomarkers for improved safety assessments. In Systems Toxicology, quantitative systems-wide molecular changes in the context of an exposure are measured, and a causal chain of molecular events linking exposures with adverse outcomes (i.e., functional and apical end points) is deciphered. Mathematical models are then built to describe these processes in a quantitative manner. The integrated data analysis leads to the identification of how biological networks are perturbed by the exposure and enables the development of predictive mathematical models of toxicological processes. This perspective integrates current knowledge regarding bioanalytical approaches, computational analysis, and the potential for improved risk assessment. PMID:24446777

Systems toxicology: from basic research to risk assessment.

PubMed

Sturla, Shana J; Boobis, Alan R; FitzGerald, Rex E; Hoeng, Julia; Kavlock, Robert J; Schirmer, Kristin; Whelan, Maurice; Wilks, Martin F; Peitsch, Manuel C

2014-03-17

Systems Toxicology is the integration of classical toxicology with quantitative analysis of large networks of molecular and functional changes occurring across multiple levels of biological organization. Society demands increasingly close scrutiny of the potential health risks associated with exposure to chemicals present in our everyday life, leading to an increasing need for more predictive and accurate risk-assessment approaches. Developing such approaches requires a detailed mechanistic understanding of the ways in which xenobiotic substances perturb biological systems and lead to adverse outcomes. Thus, Systems Toxicology approaches offer modern strategies for gaining such mechanistic knowledge by combining advanced analytical and computational tools. Furthermore, Systems Toxicology is a means for the identification and application of biomarkers for improved safety assessments. In Systems Toxicology, quantitative systems-wide molecular changes in the context of an exposure are measured, and a causal chain of molecular events linking exposures with adverse outcomes (i.e., functional and apical end points) is deciphered. Mathematical models are then built to describe these processes in a quantitative manner. The integrated data analysis leads to the identification of how biological networks are perturbed by the exposure and enables the development of predictive mathematical models of toxicological processes. This perspective integrates current knowledge regarding bioanalytical approaches, computational analysis, and the potential for improved risk assessment.

Integration of RAMS in LCC analysis for linear transport infrastructures. A case study for railways.

NASA Astrophysics Data System (ADS)

Calle-Cordón, Álvaro; Jiménez-Redondo, Noemi; Morales-Gámiz, F. J.; García-Villena, F. A.; Garmabaki, Amir H. S.; Odelius, Johan

2017-09-01

Life-cycle cost (LCC) analysis is an economic technique used to assess the total costs associated with the lifetime of a system in order to support decision making in long term strategic planning. For complex systems, such as railway and road infrastructures, the cost of maintenance plays an important role in the LCC analysis. Costs associated with maintenance interventions can be more reliably estimated by integrating the probabilistic nature of the failures associated to these interventions in the LCC models. Reliability, Maintainability, Availability and Safety (RAMS) parameters describe the maintenance needs of an asset in a quantitative way by using probabilistic information extracted from registered maintenance activities. Therefore, the integration of RAMS in the LCC analysis allows obtaining reliable predictions of system maintenance costs and the dependencies of these costs with specific cost drivers through sensitivity analyses. This paper presents an innovative approach for a combined RAMS & LCC methodology for railway and road transport infrastructures being developed under the on-going H2020 project INFRALERT. Such RAMS & LCC analysis provides relevant probabilistic information to be used for condition and risk-based planning of maintenance activities as well as for decision support in long term strategic investment planning.

Gendermetrics.NET: a novel software for analyzing the gender representation in scientific authoring.

PubMed

Bendels, Michael H K; Brüggmann, Dörthe; Schöffel, Norman; Groneberg, David A

2016-01-01

Imbalances in female career promotion are believed to be strong in the field of academic science. A primary parameter to analyze gender inequalities is the gender authoring in scientific publications. Since the presently available data on gender distribution is largely limited to underpowered studies, we here develop a new approach to analyze authors' genders in large bibliometric databases. A SQL-Server based multiuser software suite was developed that serves as an integrative tool for analyzing bibliometric data with a special emphasis on gender and topographical analysis. The presented system allows seamless integration, inspection, modification, evaluation and visualization of bibliometric data. By providing an adaptive and almost fully automatic integration and analysis process, the inter-individual variability of analysis is kept at a low level. Depending on the scientific question, the system enables the user to perform a scientometric analysis including its visualization within a short period of time. In summary, a new software suite for analyzing gender representations in scientific articles was established. The system is suitable for the comparative analysis of scientific structures on the level of continents, countries, cities, city regions, institutions, research fields and journals.

A multi-tissue type genome-scale metabolic network for analysis of whole-body systems physiology

PubMed Central

2011-01-01

Background Genome-scale metabolic reconstructions provide a biologically meaningful mechanistic basis for the genotype-phenotype relationship. The global human metabolic network, termed Recon 1, has recently been reconstructed allowing the systems analysis of human metabolic physiology and pathology. Utilizing high-throughput data, Recon 1 has recently been tailored to different cells and tissues, including the liver, kidney, brain, and alveolar macrophage. These models have shown utility in the study of systems medicine. However, no integrated analysis between human tissues has been done. Results To describe tissue-specific functions, Recon 1 was tailored to describe metabolism in three human cells: adipocytes, hepatocytes, and myocytes. These cell-specific networks were manually curated and validated based on known cellular metabolic functions. To study intercellular interactions, a novel multi-tissue type modeling approach was developed to integrate the metabolic functions for the three cell types, and subsequently used to simulate known integrated metabolic cycles. In addition, the multi-tissue model was used to study diabetes: a pathology with systemic properties. High-throughput data was integrated with the network to determine differential metabolic activity between obese and type II obese gastric bypass patients in a whole-body context. Conclusion The multi-tissue type modeling approach presented provides a platform to study integrated metabolic states. As more cell and tissue-specific models are released, it is critical to develop a framework in which to study their interdependencies. PMID:22041191

Purdue ionomics information management system. An integrated functional genomics platform.

PubMed

Baxter, Ivan; Ouzzani, Mourad; Orcun, Seza; Kennedy, Brad; Jandhyala, Shrinivas S; Salt, David E

2007-02-01

The advent of high-throughput phenotyping technologies has created a deluge of information that is difficult to deal with without the appropriate data management tools. These data management tools should integrate defined workflow controls for genomic-scale data acquisition and validation, data storage and retrieval, and data analysis, indexed around the genomic information of the organism of interest. To maximize the impact of these large datasets, it is critical that they are rapidly disseminated to the broader research community, allowing open access for data mining and discovery. We describe here a system that incorporates such functionalities developed around the Purdue University high-throughput ionomics phenotyping platform. The Purdue Ionomics Information Management System (PiiMS) provides integrated workflow control, data storage, and analysis to facilitate high-throughput data acquisition, along with integrated tools for data search, retrieval, and visualization for hypothesis development. PiiMS is deployed as a World Wide Web-enabled system, allowing for integration of distributed workflow processes and open access to raw data for analysis by numerous laboratories. PiiMS currently contains data on shoot concentrations of P, Ca, K, Mg, Cu, Fe, Zn, Mn, Co, Ni, B, Se, Mo, Na, As, and Cd in over 60,000 shoot tissue samples of Arabidopsis (Arabidopsis thaliana), including ethyl methanesulfonate, fast-neutron and defined T-DNA mutants, and natural accession and populations of recombinant inbred lines from over 800 separate experiments, representing over 1,000,000 fully quantitative elemental concentrations. PiiMS is accessible at www.purdue.edu/dp/ionomics.

Multi-Disciplinary Analysis for Future Launch Systems Using NASA's Advanced Engineering Environment (AEE)

NASA Technical Reports Server (NTRS)

Monell, D.; Mathias, D.; Reuther, J.; Garn, M.

2003-01-01

A new engineering environment constructed for the purposes of analyzing and designing Reusable Launch Vehicles (RLVs) is presented. The new environment has been developed to allow NASA to perform independent analysis and design of emerging RLV architectures and technologies. The new Advanced Engineering Environment (AEE) is both collaborative and distributed. It facilitates integration of the analyses by both vehicle performance disciplines and life-cycle disciplines. Current performance disciplines supported include: weights and sizing, aerodynamics, trajectories, propulsion, structural loads, and CAD-based geometries. Current life-cycle disciplines supported include: DDT&E cost, production costs, operations costs, flight rates, safety and reliability, and system economics. Involving six NASA centers (ARC, LaRC, MSFC, KSC, GRC and JSC), AEE has been tailored to serve as a web-accessed agency-wide source for all of NASA's future launch vehicle systems engineering functions. Thus, it is configured to facilitate (a) data management, (b) automated tool/process integration and execution, and (c) data visualization and presentation. The core components of the integrated framework are a customized PTC Windchill product data management server, a set of RLV analysis and design tools integrated using Phoenix Integration's Model Center, and an XML-based data capture and transfer protocol. The AEE system has seen production use during the Initial Architecture and Technology Review for the NASA 2nd Generation RLV program, and it continues to undergo development and enhancements in support of its current main customer, the NASA Next Generation Launch Technology (NGLT) program.

Integration and Interoperability: An Analysis to Identify the Attributes for System of Systems

DTIC Science & Technology

2008-09-01

divisions of the enterprise. Examples of the current I2 are: • a nightly feed of elearning information is captured through an automated and...standardized process throughout the enterprise and • the LMS has been integrated with SkillSoft, a third party elearning software system, (http...Command (JITC) is responsible to test all programs that utilize standard interfaces to specific global nets or systems. Many times programs that

Integrative pathway knowledge bases as a tool for systems molecular medicine.

PubMed

Liang, Mingyu

2007-08-20

There exists a sense of urgency to begin to generate a cohesive assembly of biomedical knowledge as the pace of knowledge accumulation accelerates. The urgency is in part driven by the emergence of systems molecular medicine that emphasizes the combination of systems analysis and molecular dissection in the future of medical practice and research. A potentially powerful approach is to build integrative pathway knowledge bases that link organ systems function with molecules.

Numerical integration and optimization of motions for multibody dynamic systems

NASA Astrophysics Data System (ADS)

Aguilar Mayans, Joan

This thesis considers the optimization and simulation of motions involving rigid body systems. It does so in three distinct parts, with the following topics: optimization and analysis of human high-diving motions, efficient numerical integration of rigid body dynamics with contacts, and motion optimization of a two-link robot arm using Finite-Time Lyapunov Analysis. The first part introduces the concept of eigenpostures, which we use to simulate and analyze human high-diving motions. Eigenpostures are used in two different ways: first, to reduce the complexity of the optimal control problem that we solve to obtain such motions, and second, to generate an eigenposture space to which we map existing real world motions to better analyze them. The benefits of using eigenpostures are showcased through different examples. The second part reviews an extensive list of integration algorithms used for the integration of rigid body dynamics. We analyze the accuracy and stability of the different integrators in the three-dimensional space and the rotation space SO(3). Integrators with an accuracy higher than first order perform more efficiently than integrators with first order accuracy, even in the presence of contacts. The third part uses Finite-time Lyapunov Analysis to optimize motions for a two-link robot arm. Finite-Time Lyapunov Analysis diagnoses the presence of time-scale separation in the dynamics of the optimized motion and provides the information and methodology for obtaining an accurate approximation to the optimal solution, avoiding the complications that timescale separation causes for alternative solution methods.

Functional Analysis for an Integrated Capability of Arrival/Departure/Surface Management with Tactical Runway Management

NASA Technical Reports Server (NTRS)

Phojanamongkolkij, Nipa; Okuniek, Nikolai; Lohr, Gary W.; Schaper, Meilin; Christoffels, Lothar; Latorella, Kara A.

2014-01-01

The runway is a critical resource of any air transport system. It is used for arrivals, departures, and for taxiing aircraft and is universally acknowledged as a constraining factor to capacity for both surface and airspace operations. It follows that investigation of the effective use of runways, both in terms of selection and assignment as well as the timing and sequencing of the traffic is paramount to the efficient traffic flows. Both the German Aerospace Center (DLR) and NASA have developed concepts and tools to improve atomic aspects of coordinated arrival/departure/surface management operations and runway configuration management. In December 2012, NASA entered into a Collaborative Agreement with DLR. Four collaborative work areas were identified, one of which is called "Runway Management." As part of collaborative research in the "Runway Management" area, which is conducted with the DLR Institute of Flight Guidance, located in Braunschweig, the goal is to develop an integrated system comprised of the three DLR tools - arrival, departure, and surface management (collectively referred to as A/D/S-MAN) - and NASA's tactical runway configuration management (TRCM) tool. To achieve this goal, it is critical to prepare a concept of operations (ConOps) detailing how the NASA runway management and DLR arrival, departure, and surface management tools will function together to the benefit of each. To assist with the preparation of the ConOps, the integrated NASA and DLR tools are assessed through a functional analysis method described in this report. The report first provides the highlevel operational environments for air traffic management (ATM) in Germany and in the U.S., and the descriptions of the DLR's A/D/S-MAN and NASA's TRCM tools at the level of details necessary to compliment the purpose of the study. Functional analyses of each tool and a completed functional analysis of an integrated system design are presented next in the report. Future efforts to fully develop the ConOps will include: developing scenarios to fully test environmental, procedural, and data availability assumptions; executing the analysis by a walk-through of the integrated system using these scenarios; defining the appropriate role of operators in terms of their monitoring requirements and decision authority; executing the analysis by a walk-through of the integrated system with operator involvement; characterizing the environmental, system data requirements, and operator role assumptions for the ConOps.

Obtaining mathematical models for assessing efficiency of dust collectors using integrated system of analysis and data management STATISTICA Design of Experiments

NASA Astrophysics Data System (ADS)

Azarov, A. V.; Zhukova, N. S.; Kozlovtseva, E. Yu; Dobrinsky, D. R.

2018-05-01

The article considers obtaining mathematical models to assess the efficiency of the dust collectors using an integrated system of analysis and data management STATISTICA Design of Experiments. The procedure for obtaining mathematical models and data processing is considered by the example of laboratory studies on a mounted installation containing a dust collector in counter-swirling flows (CSF) using gypsum dust of various fractions. Planning of experimental studies has been carried out in order to reduce the number of experiments and reduce the cost of experimental research. A second-order non-position plan (Box-Bencken plan) was used, which reduced the number of trials from 81 to 27. The order of statistical data research of Box-Benken plan using standard tools of integrated system for analysis and data management STATISTICA Design of Experiments is considered. Results of statistical data processing with significance estimation of coefficients and adequacy of mathematical models are presented.

Integrated Design and Engineering Analysis (IDEA) Environment - Propulsion Related Module Development and Vehicle Integration

NASA Technical Reports Server (NTRS)

Kamhawi, Hilmi N.

2013-01-01

This report documents the work performed during the period from May 2011 - October 2012 on the Integrated Design and Engineering Analysis (IDEA) environment. IDEA is a collaborative environment based on an object-oriented, multidisciplinary, distributed framework using the Adaptive Modeling Language (AML). This report will focus on describing the work done in the areas of: (1) Integrating propulsion data (turbines, rockets, and scramjets) in the system, and using the data to perform trajectory analysis; (2) Developing a parametric packaging strategy for a hypersonic air breathing vehicles allowing for tank resizing when multiple fuels and/or oxidizer are part of the configuration; and (3) Vehicle scaling and closure strategies.

UAS Integration in the NAS Project: Flight Test 3 Data Analysis of JADEM-Autoresolver Detect and Avoid System

NASA Technical Reports Server (NTRS)

Gong, Chester; Wu, Minghong G.; Santiago, Confesor

2016-01-01

The Unmanned Aircraft Systems Integration in the National Airspace System project, or UAS Integration in the NAS, aims to reduce technical barriers related to safety and operational challenges associated with enabling routine UAS access to the NAS. The UAS Integration in the NAS Project conducted a flight test activity, referred to as Flight Test 3 (FT3), involving several Detect-and-Avoid (DAA) research prototype systems between June 15, 2015 and August 12, 2015 at the Armstrong Flight Research Center (AFRC). This report documents the flight testing and analysis results for the NASA Ames-developed JADEM-Autoresolver DAA system, referred to as 'Autoresolver' herein. Four flight test days (June 17, 18, 22, and July 22) were dedicated to Autoresolver testing. The objectives of this test were as follows: 1. Validate CPA prediction accuracy and detect-and-avoid (DAA, formerly known as self-separation) alerting logic in realistic flight conditions. 2. Validate DAA trajectory model including maneuvers. 3. Evaluate TCAS/DAA interoperability. 4. Inform final Minimum Operating Performance Standards (MOPS). Flight test scenarios were designed to collect data to directly address the objectives 1-3. Objective 4, inform final MOPS, was a general objective applicable to the UAS in the NAS project as a whole, of which flight test is a subset. This report presents analysis results completed in support of the UAS in the NAS project FT3 data review conducted on October 20, 2015. Due to time constraints and, to a lesser extent, TCAS data collection issues, objective 3 was not evaluated in this analysis.

Role of premission testing in the National Missile Defense system

NASA Astrophysics Data System (ADS)

Tillman, Janice V.; Atkinson, Beverly

2001-09-01

The purpose of the National Missile Defense (NMD) system is to provide detection, discrimination, engagement, interception, and negation of ballistic missile attacks targeted at the United States (U.S.), including Alaska and Hawaii. This capability is achieved through the integration of weapons, sensors, and a battle management, command, control and communications (BMC3) system. The NMD mission includes surveillance, warning, cueing, and engagement of threat objects prior to potential impact on U.S. targets. The NMD Acquisition Strategy encompasses an integrated test program using Integrated Ground Tests (IGTs), Integrated Flight Tests (IFTs), Risk Reduction Flights (RRFs), Pre Mission Tests (PMTs), Command and Control (C2) Simulations, and other Specialty Tests. The IGTs utilize software-in-the-loop/hardware-in-the-loop (SWIL / HWIL) and digital simulations. The IFTs are conducted with targets launched from Vandenberg Air Force Base (VAFB) and interceptors launched from Kwajalein Missile Range (KMR). The RRFs evaluate NMD BMC3 and NMD sensor functional performance and integration by leveraging planned Peacekeeper and Minuteman III operational test flights and other opportunities without employing the NMD interceptor. The PMTs are nondestructive System-level tests representing the use of NMD Element Test Assets in their IFT configuration and are conducted to reduce risks in achieving the IFT objectives. Specifically, PMTs are used to reduce integration, interface, and performance risks associated with Flight Tests to ensure that as much as possible, the System is tested without expending a target or an interceptor. This paper examines several critical test planning and analysis functions as they relate to the NMD Integrated Flight Test program and, in particular, to Pre-Mission Testing. Topics to be discussed include: - Flight-test program planning; - Pre-Test Integration activities; and - Test Execution, Analysis, and Post-Flight Reconstruction.

Development of deployable structures for large space platform systems, volume 1

NASA Technical Reports Server (NTRS)

1982-01-01

Generic deployable spacecraft configurations and deployable platform systems concepts were identified. Sizing, building block concepts, orbiter packaging, thermal analysis, cost analysis, and mass properties analysis as related to platform systems integration are considered. Technology needs are examined and the major criteria used in concept selection are delineated. Requirements for deployable habitat modules, tunnels, and OTV hangars are considered.

Identifying novel glioma associated pathways based on systems biology level meta-analysis.

PubMed

Hu, Yangfan; Li, Jinquan; Yan, Wenying; Chen, Jiajia; Li, Yin; Hu, Guang; Shen, Bairong

2013-01-01

With recent advances in microarray technology, including genomics, proteomics, and metabolomics, it brings a great challenge for integrating this "-omics" data to analysis complex disease. Glioma is an extremely aggressive and lethal form of brain tumor, and thus the study of the molecule mechanism underlying glioma remains very important. To date, most studies focus on detecting the differentially expressed genes in glioma. However, the meta-analysis for pathway analysis based on multiple microarray datasets has not been systematically pursued. In this study, we therefore developed a systems biology based approach by integrating three types of omics data to identify common pathways in glioma. Firstly, the meta-analysis has been performed to study the overlapping of signatures at different levels based on the microarray gene expression data of glioma. Among these gene expression datasets, 12 pathways were found in GeneGO database that shared by four stages. Then, microRNA expression profiles and ChIP-seq data were integrated for the further pathway enrichment analysis. As a result, we suggest 5 of these pathways could be served as putative pathways in glioma. Among them, the pathway of TGF-beta-dependent induction of EMT via SMAD is of particular importance. Our results demonstrate that the meta-analysis based on systems biology level provide a more useful approach to study the molecule mechanism of complex disease. The integration of different types of omics data, including gene expression microarrays, microRNA and ChIP-seq data, suggest some common pathways correlated with glioma. These findings will offer useful potential candidates for targeted therapeutic intervention of glioma.

A Comprehensive Database and Analysis Framework To Incorporate Multiscale Data Types and Enable Integrated Analysis of Bioactive Polyphenols.

PubMed

Ho, Lap; Cheng, Haoxiang; Wang, Jun; Simon, James E; Wu, Qingli; Zhao, Danyue; Carry, Eileen; Ferruzzi, Mario G; Faith, Jeremiah; Valcarcel, Breanna; Hao, Ke; Pasinetti, Giulio M

2018-03-05

The development of a given botanical preparation for eventual clinical application requires extensive, detailed characterizations of the chemical composition, as well as the biological availability, biological activity, and safety profiles of the botanical. These issues are typically addressed using diverse experimental protocols and model systems. Based on this consideration, in this study we established a comprehensive database and analysis framework for the collection, collation, and integrative analysis of diverse, multiscale data sets. Using this framework, we conducted an integrative analysis of heterogeneous data from in vivo and in vitro investigation of a complex bioactive dietary polyphenol-rich preparation (BDPP) and built an integrated network linking data sets generated from this multitude of diverse experimental paradigms. We established a comprehensive database and analysis framework as well as a systematic and logical means to catalogue and collate the diverse array of information gathered, which is securely stored and added to in a standardized manner to enable fast query. We demonstrated the utility of the database in (1) a statistical ranking scheme to prioritize response to treatments and (2) in depth reconstruction of functionality studies. By examination of these data sets, the system allows analytical querying of heterogeneous data and the access of information related to interactions, mechanism of actions, functions, etc., which ultimately provide a global overview of complex biological responses. Collectively, we present an integrative analysis framework that leads to novel insights on the biological activities of a complex botanical such as BDPP that is based on data-driven characterizations of interactions between BDPP-derived phenolic metabolites and their mechanisms of action, as well as synergism and/or potential cancellation of biological functions. Out integrative analytical approach provides novel means for a systematic integrative analysis of heterogeneous data types in the development of complex botanicals such as polyphenols for eventual clinical and translational applications.

Development of an integrated medical supply information system

NASA Astrophysics Data System (ADS)

Xu, Eric; Wermus, Marek; Blythe Bauman, Deborah

2011-08-01

The integrated medical supply inventory control system introduced in this study is a hybrid system that is shaped by the nature of medical supply, usage and storage capacity limitations of health care facilities. The system links demand, service provided at the clinic, health care service provider's information, inventory storage data and decision support tools into an integrated information system. ABC analysis method, economic order quantity model, two-bin method and safety stock concept are applied as decision support models to tackle inventory management issues at health care facilities. In the decision support module, each medical item and storage location has been scrutinised to determine the best-fit inventory control policy. The pilot case study demonstrates that the integrated medical supply information system holds several advantages for inventory managers, since it entails benefits of deploying enterprise information systems to manage medical supply and better patient services.

Uses of GIS for Homeland Security and Emergency Management for Higher Education Institutions

ERIC Educational Resources Information Center

Murchison, Stuart B.

2010-01-01

Geographic information systems (GIS) are a major component of the geospatial sciences, which are also composed of geostatistical analysis, remote sensing, and global positional satellite systems. These systems can be integrated into GIS for georeferencing, pattern analysis, visualization, and understanding spatial concepts that transcend…

Philosophical Basis and Some Historical Aspects of Systems Biology: From Hegel to Noble - Applications for Bioenergetic Research

PubMed Central

Saks, Valdur; Monge, Claire; Guzun, Rita

2009-01-01

We live in times of paradigmatic changes for the biological sciences. Reductionism, that for the last six decades has been the philosophical basis of biochemistry and molecular biology, is being displaced by Systems Biology, which favors the study of integrated systems. Historically, Systems Biology - defined as the higher level analysis of complex biological systems - was pioneered by Claude Bernard in physiology, Norbert Wiener with the development of cybernetics, and Erwin Schrödinger in his thermodynamic approach to the living. Systems Biology applies methods inspired by cybernetics, network analysis, and non-equilibrium dynamics of open systems. These developments follow very precisely the dialectical principles of development from thesis to antithesis to synthesis discovered by Hegel. Systems Biology opens new perspectives for studies of the integrated processes of energy metabolism in different cells. These integrated systems acquire new, system-level properties due to interaction of cellular components, such as metabolic compartmentation, channeling and functional coupling mechanisms, which are central for regulation of the energy fluxes. State of the art of these studies in the new area of Molecular System Bioenergetics is analyzed. PMID:19399243

Coal gasification systems engineering and analysis. Appendix A: Coal gasification catalog

NASA Technical Reports Server (NTRS)

1980-01-01

The scope of work in preparing the Coal Gasification Data Catalog included the following subtasks: (1) candidate system subsystem definition, (2) raw materials analysis, (3) market analysis for by-products, (4) alternate products analysis, (5) preliminary integrated facility requirements. Definition of candidate systems/subsystems includes the identity of and alternates for each process unit, raw material requirements, and the cost and design drivers for each process design.

NREL Spectrum of Clean Energy Innovation (Brochure)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

2011-09-01

This brochure describes the NREL Spectrum of Clean Energy Innovation, which includes analysis and decision support, fundamental science, market relevant research, systems integration, testing and validation, commercialization and deployment. Through deep technical expertise and an unmatched breadth of capabilities, the National Renewable Energy Laboratory (NREL) leads an integrated approach across the spectrum of renewable energy innovation. From scientific discovery to accelerating market deployment, NREL works in partnership with private industry to drive the transformation of our nation's energy systems. NREL integrates the entire spectrum of innovation, including fundamental science, market relevant research, systems integration, testing and validation, commercialization, and deployment.more » Our world-class analysis and decision support informs every point on the spectrum. The innovation process at NREL is inter-dependent and iterative. Many scientific breakthroughs begin in our own laboratories, but new ideas and technologies may come to NREL at any point along the innovation spectrum to be validated and refined for commercial use.« less

Micro-optics for microfluidic analytical applications.

PubMed

Yang, Hui; Gijs, Martin A M

2018-02-19

This critical review summarizes the developments in the integration of micro-optical elements with microfluidic platforms for facilitating detection and automation of bio-analytical applications. Micro-optical elements, made by a variety of microfabrication techniques, advantageously contribute to the performance of an analytical system, especially when the latter has microfluidic features. Indeed the easy integration of optical control and detection modules with microfluidic technology helps to bridge the gap between the macroscopic world and chip-based analysis, paving the way for automated and high-throughput applications. In our review, we start the discussion with an introduction of microfluidic systems and micro-optical components, as well as aspects of their integration. We continue with a detailed description of different microfluidic and micro-optics technologies and their applications, with an emphasis on the realization of optical waveguides and microlenses. The review continues with specific sections highlighting the advantages of integrated micro-optical components in microfluidic systems for tackling a variety of analytical problems, like cytometry, nucleic acid and protein detection, cell biology, and chemical analysis applications.

DISPLA: decision information system for procurement and logistics analysis

NASA Astrophysics Data System (ADS)

Calvo, Alberto B.; Danish, Alexander J.; Lamonakis, Gregory G.

2002-08-01

This paper describes an information-exchange system for Display systems acquisition and logistics support. DISPLA (Decision Information System for Procurement and Logistics Analysis) is an Internet-based system concept for bringing sellers (display system and component suppliers) and buyers (Government Program Offices and System Integrators) together in an electronic exchange to improve the acquisition and logistics analysis support of Flat Panel Displays for the military. A proof-of-concept demonstration is presented in this paper using sample data from vendor Web sites and Government data sources.

Integrated analysis of error detection and recovery

NASA Technical Reports Server (NTRS)

Shin, K. G.; Lee, Y. H.

1985-01-01

An integrated modeling and analysis of error detection and recovery is presented. When fault latency and/or error latency exist, the system may suffer from multiple faults or error propagations which seriously deteriorate the fault-tolerant capability. Several detection models that enable analysis of the effect of detection mechanisms on the subsequent error handling operations and the overall system reliability were developed. Following detection of the faulty unit and reconfiguration of the system, the contaminated processes or tasks have to be recovered. The strategies of error recovery employed depend on the detection mechanisms and the available redundancy. Several recovery methods including the rollback recovery are considered. The recovery overhead is evaluated as an index of the capabilities of the detection and reconfiguration mechanisms.

A comparative study of biomass integrated gasification combined cycle power systems: Performance analysis.

PubMed

Zang, Guiyan; Tejasvi, Sharma; Ratner, Albert; Lora, Electo Silva

2018-05-01

The Biomass Integrated Gasification Combined Cycle (BIGCC) power system is believed to potentially be a highly efficient way to utilize biomass to generate power. However, there is no comparative study of BIGCC systems that examines all the latest improvements for gasification agents, gas turbine combustion methods, and CO 2 Capture and Storage options. This study examines the impact of recent advancements on BIGCC performance through exergy analysis using Aspen Plus. Results show that the exergy efficiency of these systems is ranged from 22.3% to 37.1%. Furthermore, exergy analysis indicates that the gas turbine with external combustion has relatively high exergy efficiency, and Selexol CO 2 removal method has low exergy destruction. Moreover, the sensitivity analysis shows that the system exergy efficiency is more sensitive to the initial temperature and pressure ratio of the gas turbine, whereas has a relatively weak dependence on the initial temperature and initial pressure of the steam turbine. Copyright © 2018 Elsevier Ltd. All rights reserved.

Comparative cost analysis of inpatient integrative medicine-Results of a pilot study.

PubMed

Ostermann, Thomas; Lauche, Romy; Cramer, Holger; Dobos, Gustav

2017-06-01

Costs of integrative treatment alone and in comparison with other treatment approaches have scarcely been reported in the past. This study presents results of a comparative cost analysis of an inpatient integrative medicine treatment costs. Data from 2006 for inpatients referred to a Department of Integrative Medicine in Germany were used. Case-related treatment costs were calculated, and transformed into Casemix-Indices and revenues per DRG. Costs were compared between departments at the same hospital and between different hospitals using univariate statistics and Chi-Square tests. In total 1253 inpatients (81.4% female, 61.1±14.4years) were included in the current analysis. Most patients were treated for diseases of the musculoskeletal system (57.2%), followed by diseases of the digestive system (11.4%), and diseases of the nervous system (10.4%). The department received an additional payment for most of the patients (88.0%), which led to an effective appreciation of 10.8% per case compared to the standardized Casemix-Index. In-house comparisons with other departments found the department in close vicinity to the departments of Internal medicine with regards to CMI and mean revenue, however the Patient Clinical Complexity Level was significantly lower in the Integrative medicine department. The interhospital comparison revealed comparable Casemix-Index and DRG-revenue, however the additional payment increased the mean revenue significantly. Modern integrative in-patient treatment is mostly cost-equivalent to conventional treatment. Cost effectiveness studies should be considered to further investigate the potential of integrative in patient treatment. Copyright © 2016 Elsevier Ltd. All rights reserved.

LLIMAS: Revolutionizing integrating modeling and analysis at MIT Lincoln Laboratory

NASA Astrophysics Data System (ADS)

Doyle, Keith B.; Stoeckel, Gerhard P.; Rey, Justin J.; Bury, Mark E.

2017-08-01

MIT Lincoln Laboratory's Integrated Modeling and Analysis Software (LLIMAS) enables the development of novel engineering solutions for advanced prototype systems through unique insights into engineering performance and interdisciplinary behavior to meet challenging size, weight, power, environmental, and performance requirements. LLIMAS is a multidisciplinary design optimization tool that wraps numerical optimization algorithms around an integrated framework of structural, thermal, optical, stray light, and computational fluid dynamics analysis capabilities. LLIMAS software is highly extensible and has developed organically across a variety of technologies including laser communications, directed energy, photometric detectors, chemical sensing, laser radar, and imaging systems. The custom software architecture leverages the capabilities of existing industry standard commercial software and supports the incorporation of internally developed tools. Recent advances in LLIMAS's Structural-Thermal-Optical Performance (STOP), aeromechanical, and aero-optical capabilities as applied to Lincoln prototypes are presented.

Navigation integrity monitoring and obstacle detection for enhanced-vision systems

NASA Astrophysics Data System (ADS)

Korn, Bernd; Doehler, Hans-Ullrich; Hecker, Peter

2001-08-01

Typically, Enhanced Vision (EV) systems consist of two main parts, sensor vision and synthetic vision. Synthetic vision usually generates a virtual out-the-window view using databases and accurate navigation data, e. g. provided by differential GPS (DGPS). The reliability of the synthetic vision highly depends on both, the accuracy of the used database and the integrity of the navigation data. But especially in GPS based systems, the integrity of the navigation can't be guaranteed. Furthermore, only objects that are stored in the database can be displayed to the pilot. Consequently, unexpected obstacles are invisible and this might cause severe problems. Therefore, additional information has to be extracted from sensor data to overcome these problems. In particular, the sensor data analysis has to identify obstacles and has to monitor the integrity of databases and navigation. Furthermore, if a lack of integrity arises, navigation data, e.g. the relative position of runway and aircraft, has to be extracted directly from the sensor data. The main contribution of this paper is about the realization of these three sensor data analysis tasks within our EV system, which uses the HiVision 35 GHz MMW radar of EADS, Ulm as the primary EV sensor. For the integrity monitoring, objects extracted from radar images are registered with both database objects and objects (e. g. other aircrafts) transmitted via data link. This results in a classification into known and unknown radar image objects and consequently, in a validation of the integrity of database and navigation. Furthermore, special runway structures are searched for in the radar image where they should appear. The outcome of this runway check contributes to the integrity analysis, too. Concurrent to this investigation a radar image based navigation is performed without using neither precision navigation nor detailed database information to determine the aircraft's position relative to the runway. The performance of our approach is demonstrated with real data acquired during extensive flight tests to several airports in Northern Germany.

On the complete and partial integrability of non-Hamiltonian systems

NASA Astrophysics Data System (ADS)

Bountis, T. C.; Ramani, A.; Grammaticos, B.; Dorizzi, B.

1984-11-01

The methods of singularity analysis are applied to several third order non-Hamiltonian systems of physical significance including the Lotka-Volterra equations, the three-wave interaction and the Rikitake dynamo model. Complete integrability is defined and new completely integrable systems are discovered by means of the Painlevé property. In all these cases we obtain integrals, which reduce the equations either to a final quadrature or to an irreducible second order ordinary differential equation (ODE) solved by Painlevé transcendents. Relaxing the Painlevé property we find many partially integrable cases whose movable singularities are poles at leading order, with In( t- t0) terms entering at higher orders. In an Nth order, generalized Rössler model a precise relation is established between the partial fulfillment of the Painlevé conditions and the existence of N - 2 integrals of the motion.

Analysis of DISMS (Defense Integrated Subsistence Management System) Increment 4

DTIC Science & Technology

1988-12-01

response data entry; and rationale supporting an on-line system based on real time management information needs. Keywords: Automated systems; Subsistence; Workload capacity; Bid response; Contract administration; Computer systems.

Shuttle: Reaction control system. Cryogenic liquid distribution system: Study

NASA Technical Reports Server (NTRS)

Akkerman, J. W.

1972-01-01

A cryogenic liquid distribution system suitable for the reaction control system on space shuttles is described. The system thermodynamics, operation, performance and weight analysis are discussed along with the design, maintenance and integration concepts.

Building a functional, integrated GIS/remote sensing resource analysis and planning system. [Utah

NASA Technical Reports Server (NTRS)

Ridd, M. K.; Wheeler, D. J.

1985-01-01

To be an effective tool for resource analysis and planning, a geographic information system (GIS) needs to be integrated with a digital remote sensing capability. To be truly functional, the paired system must be driven by grass roots local needs. A case study couched in a Soil Conservation District in northern Utah is presented. Agency representatives determined that the most fundamental data sets to be entered into the GIS system analysis system in the first round were: land use/land cover; geomorphic/soil unit data; hydrologic unit data; and digital terrain. The least expensive and best ways to obtain these data were determined. Data were acquired and formatted to enter the state's PRIME/ARC-INFO GIS, and are being interrogated for resource management decisions related to such issues as agricultural preservation, urban expansion, soil erosion control, and dam siting.

Nuclear plants gain integrated information systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Villavicencio-Ramirez, A.; Rodriquez-Alvarez, J.M.

1994-10-01

With the objective of simplifying the complex mesh of computing devices employed within nuclear power plants, modern technology and integration techniques are being used to form centralized (but backed up) databases and distributed processing and display networks. Benefits are immediate as a result of the integration and the use of standards. The use of a unique data acquisition and database subsystem optimizes the high costs of engineering, as this task is done only once for the life span of the system. This also contributes towards a uniform user interface and allows for graceful expansion and maintenance. This article features anmore » integrated information system, Sistema Integral de Informacion de Proceso (SIIP). The development of this system enabled the Laguna Verde Nuclear Power plant to fully use the already existing universe of signals and its related engineering during all plant conditions, namely, start up, normal operation, transient analysis, and emergency operation. Integrated systems offer many advantages over segregated systems, and this experience should benefit similar development efforts in other electric power utilities, not only for nuclear but also for other types of generating plants.« less

Better Assessment Science Integrating Point and Non-point Sources (BASINS)

EPA Pesticide Factsheets

Better Assessment Science Integrating Point and Nonpoint Sources (BASINS) is a multipurpose environmental analysis system designed to help regional, state, and local agencies perform watershed- and water quality-based studies.

ATLAS, an integrated structural analysis and design system. Volume 3: User's manual, input and execution data

NASA Technical Reports Server (NTRS)

Dreisbach, R. L. (Editor)

1979-01-01

The input data and execution control statements for the ATLAS integrated structural analysis and design system are described. It is operational on the Control Data Corporation (CDC) 6600/CYBER computers in a batch mode or in a time-shared mode via interactive graphic or text terminals. ATLAS is a modular system of computer codes with common executive and data base management components. The system provides an extensive set of general-purpose technical programs with analytical capabilities including stiffness, stress, loads, mass, substructuring, strength design, unsteady aerodynamics, vibration, and flutter analyses. The sequence and mode of execution of selected program modules are controlled via a common user-oriented language.

Preliminary analysis of an integrated logistics system for OSSA payloads. Volume 3: OSSA integrated logistics support planning document

NASA Technical Reports Server (NTRS)

Palguta, T.; Bradley, W.; Stockton, T.

1988-01-01

Guidance in preparing and updating an integrated logistics support plan (ILSP) is given. Clear, concise, and detailed instructions are provided on the preparation and content of an ILSP in order to ensure a quality document that reflects total program requirements.

An interval precise integration method for transient unbalance response analysis of rotor system with uncertainty

NASA Astrophysics Data System (ADS)

Fu, Chao; Ren, Xingmin; Yang, Yongfeng; Xia, Yebao; Deng, Wangqun

2018-07-01

A non-intrusive interval precise integration method (IPIM) is proposed in this paper to analyze the transient unbalance response of uncertain rotor systems. The transfer matrix method (TMM) is used to derive the deterministic equations of motion of a hollow-shaft overhung rotor. The uncertain transient dynamic problem is solved by combing the Chebyshev approximation theory with the modified precise integration method (PIM). Transient response bounds are calculated by interval arithmetic of the expansion coefficients. Theoretical error analysis of the proposed method is provided briefly, and its accuracy is further validated by comparing with the scanning method in simulations. Numerical results show that the IPIM can keep good accuracy in vibration prediction of the start-up transient process. Furthermore, the proposed method can also provide theoretical guidance to other transient dynamic mechanical systems with uncertainties.

Multidisciplinary System Reliability Analysis

NASA Technical Reports Server (NTRS)

Mahadevan, Sankaran; Han, Song; Chamis, Christos C. (Technical Monitor)

2001-01-01

The objective of this study is to develop a new methodology for estimating the reliability of engineering systems that encompass multiple disciplines. The methodology is formulated in the context of the NESSUS probabilistic structural analysis code, developed under the leadership of NASA Glenn Research Center. The NESSUS code has been successfully applied to the reliability estimation of a variety of structural engineering systems. This study examines whether the features of NESSUS could be used to investigate the reliability of systems in other disciplines such as heat transfer, fluid mechanics, electrical circuits etc., without considerable programming effort specific to each discipline. In this study, the mechanical equivalence between system behavior models in different disciplines are investigated to achieve this objective. A new methodology is presented for the analysis of heat transfer, fluid flow, and electrical circuit problems using the structural analysis routines within NESSUS, by utilizing the equivalence between the computational quantities in different disciplines. This technique is integrated with the fast probability integration and system reliability techniques within the NESSUS code, to successfully compute the system reliability of multidisciplinary systems. Traditional as well as progressive failure analysis methods for system reliability estimation are demonstrated, through a numerical example of a heat exchanger system involving failure modes in structural, heat transfer and fluid flow disciplines.

Multi-Disciplinary System Reliability Analysis

NASA Technical Reports Server (NTRS)

Mahadevan, Sankaran; Han, Song

1997-01-01

The objective of this study is to develop a new methodology for estimating the reliability of engineering systems that encompass multiple disciplines. The methodology is formulated in the context of the NESSUS probabilistic structural analysis code developed under the leadership of NASA Lewis Research Center. The NESSUS code has been successfully applied to the reliability estimation of a variety of structural engineering systems. This study examines whether the features of NESSUS could be used to investigate the reliability of systems in other disciplines such as heat transfer, fluid mechanics, electrical circuits etc., without considerable programming effort specific to each discipline. In this study, the mechanical equivalence between system behavior models in different disciplines are investigated to achieve this objective. A new methodology is presented for the analysis of heat transfer, fluid flow, and electrical circuit problems using the structural analysis routines within NESSUS, by utilizing the equivalence between the computational quantities in different disciplines. This technique is integrated with the fast probability integration and system reliability techniques within the NESSUS code, to successfully compute the system reliability of multi-disciplinary systems. Traditional as well as progressive failure analysis methods for system reliability estimation are demonstrated, through a numerical example of a heat exchanger system involving failure modes in structural, heat transfer and fluid flow disciplines.

A Multimodal Emotion Detection System during Human-Robot Interaction

PubMed Central

Alonso-Martín, Fernando; Malfaz, María; Sequeira, João; Gorostiza, Javier F.; Salichs, Miguel A.

2013-01-01

In this paper, a multimodal user-emotion detection system for social robots is presented. This system is intended to be used during human–robot interaction, and it is integrated as part of the overall interaction system of the robot: the Robotics Dialog System (RDS). Two modes are used to detect emotions: the voice and face expression analysis. In order to analyze the voice of the user, a new component has been developed: Gender and Emotion Voice Analysis (GEVA), which is written using the Chuck language. For emotion detection in facial expressions, the system, Gender and Emotion Facial Analysis (GEFA), has been also developed. This last system integrates two third-party solutions: Sophisticated High-speed Object Recognition Engine (SHORE) and Computer Expression Recognition Toolbox (CERT). Once these new components (GEVA and GEFA) give their results, a decision rule is applied in order to combine the information given by both of them. The result of this rule, the detected emotion, is integrated into the dialog system through communicative acts. Hence, each communicative act gives, among other things, the detected emotion of the user to the RDS so it can adapt its strategy in order to get a greater satisfaction degree during the human–robot dialog. Each of the new components, GEVA and GEFA, can also be used individually. Moreover, they are integrated with the robotic control platform ROS (Robot Operating System). Several experiments with real users were performed to determine the accuracy of each component and to set the final decision rule. The results obtained from applying this decision rule in these experiments show a high success rate in automatic user emotion recognition, improving the results given by the two information channels (audio and visual) separately. PMID:24240598

Man-Machine Integration Design and Analysis System (MIDAS) v5: Augmentations, Motivations, and Directions for Aeronautics Applications

NASA Technical Reports Server (NTRS)

Gore, Brian F.

2011-01-01

As automation and advanced technologies are introduced into transport systems ranging from the Next Generation Air Transportation System termed NextGen, to the advanced surface transportation systems as exemplified by the Intelligent Transportations Systems, to future systems designed for space exploration, there is an increased need to validly predict how the future systems will be vulnerable to error given the demands imposed by the assistive technologies. One formalized approach to study the impact of assistive technologies on the human operator in a safe and non-obtrusive manner is through the use of human performance models (HPMs). HPMs play an integral role when complex human-system designs are proposed, developed, and tested. One HPM tool termed the Man-machine Integration Design and Analysis System (MIDAS) is a NASA Ames Research Center HPM software tool that has been applied to predict human-system performance in various domains since 1986. MIDAS is a dynamic, integrated HPM and simulation environment that facilitates the design, visualization, and computational evaluation of complex man-machine system concepts in simulated operational environments. The paper will discuss a range of aviation specific applications including an approach used to model human error for NASA s Aviation Safety Program, and what-if analyses to evaluate flight deck technologies for NextGen operations. This chapter will culminate by raising two challenges for the field of predictive HPMs for complex human-system designs that evaluate assistive technologies: that of (1) model transparency and (2) model validation.

Applications of CCSDS recommendations to Integrated Ground Data Systems (IGDS)

NASA Technical Reports Server (NTRS)

Mizuta, Hiroshi; Martin, Daniel; Kato, Hatsuhiko; Ihara, Hirokazu

1993-01-01

This paper describes an application of the CCSDS Principle Network (CPH) service model to communications network elements of a postulated Integrated Ground Data System (IGDS). Functions are drawn principally from COSMICS (Cosmic Information and Control System), an integrated space control infrastructure, and the Earth Observing System Data and Information System (EOSDIS) Core System (ECS). From functional requirements, this paper derives a set of five communications network partitions which, taken together, support proposed space control infrastructures and data distribution systems. Our functional analysis indicates that the five network partitions derived in this paper should effectively interconnect the users, centers, processors, and other architectural elements of an IGDS. This paper illustrates a useful application of the CCSDS (Consultive Committee for Space Data Systems) Recommendations to ground data system development.

Grid-Integrated Electric Drive Analysis for The Ohio State University |

Science.gov Websites

thermal management analysis and simulations on a high-performance, high-speed drive-developed by The Ohio as a pilot study for the future generation of energy efficient, high power density, high-speed integrated medium/high-voltage drive systems. If successful, the proposed project will significantly advance

A web-enabled system for integrated assessment of watershed development

USGS Publications Warehouse

Dymond, R.; Lohani, V.; Regmi, B.; Dietz, R.

2004-01-01

Researchers at Virginia Tech have put together the primary structure of a web enabled integrated modeling system that has potential to be a planning tool to help decision makers and stakeholders in making appropriate watershed management decisions. This paper describes the integrated system, including data sources, collection, analysis methods, system software and design, and issues of integrating the various component models. The integrated system has three modeling components, namely hydrology, economics, and fish health, and is accompanied by descriptive 'help files.' Since all three components have a related spatial aspect, GIS technology provides the integration platform. When completed, a user will access the integrated system over the web to choose pre-selected land development patterns to create a 'what if' scenario using an easy-to-follow interface. The hydrologic model simulates effects of the scenario on annual runoff volume, flood peaks of various return periods, and ground water recharge. The economics model evaluates tax revenue and fiscal costs as a result of a new land development scenario. The fish health model evaluates effects of new land uses in zones of influence to the health of fish populations in those areas. Copyright ASCE 2004.

A linear circuit analysis program with stiff systems capability

NASA Technical Reports Server (NTRS)

Cook, C. H.; Bavuso, S. J.

1973-01-01

Several existing network analysis programs have been modified and combined to employ a variable topological approach to circuit translation. Efficient numerical integration techniques are used for transient analysis.

Using the Unified Modelling Language (UML) to guide the systemic description of biological processes and systems.

PubMed

Roux-Rouquié, Magali; Caritey, Nicolas; Gaubert, Laurent; Rosenthal-Sabroux, Camille

2004-07-01

One of the main issues in Systems Biology is to deal with semantic data integration. Previously, we examined the requirements for a reference conceptual model to guide semantic integration based on the systemic principles. In the present paper, we examine the usefulness of the Unified Modelling Language (UML) to describe and specify biological systems and processes. This makes unambiguous representations of biological systems, which would be suitable for translation into mathematical and computational formalisms, enabling analysis, simulation and prediction of these systems behaviours.

Scaling Analysis Techniques to Establish Experimental Infrastructure for Component, Subsystem, and Integrated System Testing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sabharwall, Piyush; O'Brien, James E.; McKellar, Michael G.

2015-03-01

Hybrid energy system research has the potential to expand the application for nuclear reactor technology beyond electricity. The purpose of this research is to reduce both technical and economic risks associated with energy systems of the future. Nuclear hybrid energy systems (NHES) mitigate the variability of renewable energy sources, provide opportunities to produce revenue from different product streams, and avoid capital inefficiencies by matching electrical output to demand by using excess generation capacity for other purposes when it is available. An essential step in the commercialization and deployment of this advanced technology is scaled testing to demonstrate integrated dynamic performancemore » of advanced systems and components when risks cannot be mitigated adequately by analysis or simulation. Further testing in a prototypical environment is needed for validation and higher confidence. This research supports the development of advanced nuclear reactor technology and NHES, and their adaptation to commercial industrial applications that will potentially advance U.S. energy security, economy, and reliability and further reduce carbon emissions. Experimental infrastructure development for testing and feasibility studies of coupled systems can similarly support other projects having similar developmental needs and can generate data required for validation of models in thermal energy storage and transport, energy, and conversion process development. Experiments performed in the Systems Integration Laboratory will acquire performance data, identify scalability issues, and quantify technology gaps and needs for various hybrid or other energy systems. This report discusses detailed scaling (component and integrated system) and heat transfer figures of merit that will establish the experimental infrastructure for component, subsystem, and integrated system testing to advance the technology readiness of components and systems to the level required for commercial application and demonstration under NHES.« less

Neural systems analysis of decision making during goal-directed navigation.

PubMed

Penner, Marsha R; Mizumori, Sheri J Y

2012-01-01

The ability to make adaptive decisions during goal-directed navigation is a fundamental and highly evolved behavior that requires continual coordination of perceptions, learning and memory processes, and the planning of behaviors. Here, a neurobiological account for such coordination is provided by integrating current literatures on spatial context analysis and decision-making. This integration includes discussions of our current understanding of the role of the hippocampal system in experience-dependent navigation, how hippocampal information comes to impact midbrain and striatal decision making systems, and finally the role of the striatum in the implementation of behaviors based on recent decisions. These discussions extend across cellular to neural systems levels of analysis. Not only are key findings described, but also fundamental organizing principles within and across neural systems, as well as between neural systems functions and behavior, are emphasized. It is suggested that studying decision making during goal-directed navigation is a powerful model for studying interactive brain systems and their mediation of complex behaviors. Copyright © 2011. Published by Elsevier Ltd.

ASIL determination for motorbike's Electronics Throttle Control System (ETCS) mulfunction

NASA Astrophysics Data System (ADS)

Zaman Rokhani, Fakhrul; Rahman, Muhammad Taqiuddin Abdul; Ain Kamsani, Noor; Sidek, Roslina Mohd; Saripan, M. Iqbal; Samsudin, Khairulmizam; Khair Hassan, Mohd

2017-11-01

Electronics Throttle Control System (ETCS) is the principal electronic unit in all fuel injection engine motorbike, augmenting the engine performance efficiency in comparison to the conventional carburetor based engine. ETCS is regarded as a safety-critical component, whereby ETCS malfunction can cause unintended acceleration or deceleration event, which can be hazardous to riders. In this study, Hazard Analysis and Risk Assessment, an ISO26262 functional safety standard analysis has been applied on motorbike's ETCS to determine the required automotive safety integrity level. Based on the analysis, the established automotive safety integrity level can help to derive technical and functional safety measures for ETCS development.

Lunar Exploration Architecture Level Key Drivers and Sensitivities

NASA Technical Reports Server (NTRS)

Goodliff, Kandyce; Cirillo, William; Earle, Kevin; Reeves, J. D.; Shyface, Hilary; Andraschko, Mark; Merrill, R. Gabe; Stromgren, Chel; Cirillo, Christopher

2009-01-01

Strategic level analysis of the integrated behavior of lunar transportation and lunar surface systems architecture options is performed to assess the benefit, viability, affordability, and robustness of system design choices. This analysis employs both deterministic and probabilistic modeling techniques so that the extent of potential future uncertainties associated with each option are properly characterized. The results of these analyses are summarized in a predefined set of high-level Figures of Merit (FOMs) so as to provide senior NASA Constellation Program (CxP) and Exploration Systems Mission Directorate (ESMD) management with pertinent information to better inform strategic level decision making. The strategic level exploration architecture model is designed to perform analysis at as high a level as possible but still capture those details that have major impacts on system performance. The strategic analysis methodology focuses on integrated performance, affordability, and risk analysis, and captures the linkages and feedbacks between these three areas. Each of these results leads into the determination of the high-level FOMs. This strategic level analysis methodology has been previously applied to Space Shuttle and International Space Station assessments and is now being applied to the development of the Constellation Program point-of-departure lunar architecture. This paper provides an overview of the strategic analysis methodology and the lunar exploration architecture analyses to date. In studying these analysis results, the strategic analysis team has identified and characterized key drivers affecting the integrated architecture behavior. These key drivers include inclusion of a cargo lander, mission rate, mission location, fixed-versus- variable costs/return on investment, and the requirement for probabilistic analysis. Results of sensitivity analysis performed on lunar exploration architecture scenarios are also presented.

Performance and Reliability Optimization for Aerospace Systems subject to Uncertainty and Degradation

NASA Technical Reports Server (NTRS)

Miller, David W.; Uebelhart, Scott A.; Blaurock, Carl

2004-01-01

This report summarizes work performed by the Space Systems Laboratory (SSL) for NASA Langley Research Center in the field of performance optimization for systems subject to uncertainty. The objective of the research is to develop design methods and tools to the aerospace vehicle design process which take into account lifecycle uncertainties. It recognizes that uncertainty between the predictions of integrated models and data collected from the system in its operational environment is unavoidable. Given the presence of uncertainty, the goal of this work is to develop means of identifying critical sources of uncertainty, and to combine these with the analytical tools used with integrated modeling. In this manner, system uncertainty analysis becomes part of the design process, and can motivate redesign. The specific program objectives were: 1. To incorporate uncertainty modeling, propagation and analysis into the integrated (controls, structures, payloads, disturbances, etc.) design process to derive the error bars associated with performance predictions. 2. To apply modern optimization tools to guide in the expenditure of funds in a way that most cost-effectively improves the lifecycle productivity of the system by enhancing the subsystem reliability and redundancy. The results from the second program objective are described. This report describes the work and results for the first objective: uncertainty modeling, propagation, and synthesis with integrated modeling.

Telerobotic workstation design aid

NASA Technical Reports Server (NTRS)

Corker, K.; Hudlicka, E.; Young, D.; Cramer, N.

1989-01-01

Telerobot systems are being developed to support a number of space mission applications. In low earth orbit, telerobots and teleoperated manipulators will be used in shuttle operations and space station construction/maintenance. Free flying telerobotic service vehicles will be used at low and geosynchronous orbital operations. Rovers and autonomous vehicles will be equipped with telerobotic devices in planetary exploration. In all of these systems, human operators will interact with the robot system at varied levels during the scheduled operations. The human operators may be in either orbital or ground-based control systems. To assure integrated system development and maximum utility across these systems, designers must be sensitive to the constraints and capabilities that the human brings to system operation and must be assisted in applying these human factors to system development. The simulation and analysis system is intended to serve the needs of system analysis/designers as an integrated workstation in support of telerobotic design.

Examining the effectiveness of municipal solid waste management systems: An integrated cost-benefit analysis perspective with a financial cost modeling in Taiwan

DOE Office of Scientific and Technical Information (OSTI.GOV)

Weng, Yu-Chi, E-mail: clyde.weng@gmail.com; Fujiwara, Takeshi

2011-06-15

In order to develop a sound material-cycle society, cost-effective municipal solid waste (MSW) management systems are required for the municipalities in the context of the integrated accounting system for MSW management. Firstly, this paper attempts to establish an integrated cost-benefit analysis (CBA) framework for evaluating the effectiveness of MSW management systems. In this paper, detailed cost/benefit items due to waste problems are particularly clarified. The stakeholders of MSW management systems, including the decision-makers of the municipalities and the citizens, are expected to reconsider the waste problems in depth and thus take wise actions with the aid of the proposed CBAmore » framework. Secondly, focusing on the financial cost, this study develops a generalized methodology to evaluate the financial cost-effectiveness of MSW management systems, simultaneously considering the treatment technological levels and policy effects. The impacts of the influencing factors on the annual total and average financial MSW operation and maintenance (O and M) costs are analyzed in the Taiwanese case study with a demonstrative short-term future projection of the financial costs under scenario analysis. The established methodology would contribute to the evaluation of the current policy measures and to the modification of the policy design for the municipalities.« less

Web-Based Tools for Designing and Developing Teaching Materials for Integration of Information Technology into Instruction

ERIC Educational Resources Information Center

Chang, Kuo-En; Sung, Yao-Ting; Hou, Huei-Tse

2006-01-01

Educational software for teachers is an important, yet usually ignored, link for integrating information technology into classroom instruction. This study builds a web-based teaching material design and development system. The process in the system is divided into four stages, analysis, design, development, and practice. Eight junior high school…

New Controls and Accountability for South African Teachers and Schools: The Integrated Quality Management System

ERIC Educational Resources Information Center

Weber, Everard

2005-01-01

This article analyses the Integrated Quality Management System (IQMS), an agreement reached in 2003 between the South African Education Department and the major teacher organisations in the country by using discourse analysis. The IQMS was scheduled to be implemented in public schools in 2004. Three discursive tensions are identified and…

Integrated Utility Systems Feasibility Study and Conceptual Design at the University of Florida. Executive Summary.

ERIC Educational Resources Information Center

Kirmse, Dale W.; Manyimo, Steve B.

This executive summary presents a brief analysis of findings and recommendations. The concept of the Integrated Utility System (IUS) is to consider the interaction and mutual support of five utility subsystems needed by a campus complex of buildings. The subsystems are: (1) Electric power service; (2) Heating - ventilating - air conditioning and…

System approach to the analysis of an integrated oxy-fuel combustion power plant

NASA Astrophysics Data System (ADS)

Ziębik, Andrzej; Gładysz, Paweł

2014-09-01

Oxy-fuel combustion (OFC) belongs to one of the three commonly known clean coal technologies for power generation sector and other industry sectors responsible for CO2 emissions (e.g., steel or cement production). The OFC capture technology is based on using high-purity oxygen in the combustion process instead of atmospheric air. Therefore flue gases have a high concentration of CO2. Due to the limited adiabatic temperature of combustion some part of CO2 must be recycled to the boiler in order to maintain a proper flame temperature. An integrated oxy-fuel combustion power plant constitutes a system consisting of the following technological modules: boiler, steam cycle, air separation unit, cooling water and water treatment system, flue gas quality control system and CO2 processing unit. Due to the interconnections between technological modules, energy, exergy and ecological analyses require a system approach. The paper present the system approach based on the `input-output' method to the analysis of the: direct energy and material consumption, cumulative energy and exergy consumption, system (local and cumulative) exergy losses, and thermoecological cost. Other measures like cumulative degree of perfection or index of sustainable development are also proposed. The paper presents a complex example of the system analysis (from direct energy consumption to thermoecological cost) of an advanced integrated OFC power plant.

An integrated weather and sea-state forecasting system for the Arabian Peninsula (WASSF)

NASA Astrophysics Data System (ADS)

Kallos, George; Galanis, George; Spyrou, Christos; Mitsakou, Christina; Solomos, Stavros; Bartsotas, Nikolaos; Kalogrei, Christina; Athanaselis, Ioannis; Sofianos, Sarantis; Vervatis, Vassios; Axaopoulos, Panagiotis; Papapostolou, Alexandros; Qahtani, Jumaan Al; Alaa, Elyas; Alexiou, Ioannis; Beard, Daniel

2013-04-01

Nowadays, large industrial conglomerates such as the Saudi ARAMCO, require a series of weather and sea state forecasting products that cannot be found in state meteorological offices or even commercial data providers. The two major objectives of the system is prevention and mitigation of environmental problems and of course early warning of local conditions associated with extreme weather events. The management and operations part is related to early warning of weather and sea-state events that affect operations of various facilities. The environmental part is related to air quality and especially the desert dust levels in the atmosphere. The components of the integrated system include: (i) a weather and desert dust prediction system with forecasting horizon of 5 days, (ii) a wave analysis and prediction component for Red Sea and Arabian Gulf, (iii) an ocean circulation and tidal analysis and prediction of both Red Sea and Arabian Gulf and (iv) an Aviation part specializing in the vertical structure of the atmosphere and extreme events that affect air transport and other operations. Specialized data sets required for on/offshore operations are provided ate regular basis. State of the art modeling components are integrated to a unique system that distributes the produced analysis and forecasts to each department. The weather and dust prediction system is SKIRON/Dust, the wave analysis and prediction system is based on WAM cycle 4 model from ECMWF, the ocean circulation model is MICOM while the tidal analysis and prediction is a development of the Ocean Physics and Modeling Group of University of Athens, incorporating the Tidal Model Driver. A nowcasting subsystem is included. An interactive system based on Google Maps gives the capability to extract and display the necessary information for any location of the Arabian Peninsula, the Red Sea and Arabian Gulf.

A Galleria Boundary Element Method for two-dimensional nonlinear magnetostatics

NASA Astrophysics Data System (ADS)

Brovont, Aaron D.

The Boundary Element Method (BEM) is a numerical technique for solving partial differential equations that is used broadly among the engineering disciplines. The main advantage of this method is that one needs only to mesh the boundary of a solution domain. A key drawback is the myriad of integrals that must be evaluated to populate the full system matrix. To this day these integrals have been evaluated using numerical quadrature. In this research, a Galerkin formulation of the BEM is derived and implemented to solve two-dimensional magnetostatic problems with a focus on accurate, rapid computation. To this end, exact, closed-form solutions have been derived for all the integrals comprising the system matrix as well as those required to compute fields in post-processing; the need for numerical integration has been eliminated. It is shown that calculation of the system matrix elements using analytical solutions is 15-20 times faster than with numerical integration of similar accuracy. Furthermore, through the example analysis of a c-core inductor, it is demonstrated that the present BEM formulation is a competitive alternative to the Finite Element Method (FEM) for linear magnetostatic analysis. Finally, the BEM formulation is extended to analyze nonlinear magnetostatic problems via the Dual Reciprocity Method (DRBEM). It is shown that a coarse, meshless analysis using the DRBEM is able to achieve RMS error of 3-6% compared to a commercial FEM package in lightly saturated conditions.

Complex multidisciplinary system composition for aerospace vehicle conceptual design

NASA Astrophysics Data System (ADS)

Gonzalez, Lex

Although, there exists a vast amount of work concerning the analysis, design, integration of aerospace vehicle systems, there is no standard for how this data and knowledge should be combined in order to create a synthesis system. Each institution creating a synthesis system has in house vehicle and hardware components they are attempting to model and proprietary methods with which to model them. This leads to the fact that synthesis systems begin as one-off creations meant to answer a specific problem. As the scope of the synthesis system grows to encompass more and more problems, so does its size and complexity; in order for a single synthesis system to answer multiple questions the number of methods and method interface must increase. As a means to curtail the requirement that the increase of an aircraft synthesis systems capability leads to an increase in its size and complexity, this research effort focuses on the idea that each problem in aerospace requires its own analysis framework. By focusing on the creation of a methodology which centers on the matching of an analysis framework towards the problem being solved, the complexity of the analysis framework is decoupled from the complexity of the system that creates it. The derived methodology allows for the composition of complex multi-disciplinary systems (CMDS) through the automatic creation and implementation of system and disciplinary method interfaces. The CMDS Composition process follows a four step methodology meant to take a problem definition and progress towards the creation of an analysis framework meant to answer said problem. The unique implementation of the CMDS Composition process take user selected disciplinary analysis methods and automatically integrates them, together in order to create a syntactically composable analysis framework. As a means of assessing the validity of the CMDS Composition process a prototype system (AVDDBMS) has been developed. AVD DBMS has been used to model the Generic Hypersonic Vehicle (GHV), an open source family of hypersonic vehicles originating from the Air Force Research Laboratory. AVDDBMS has been applied in three different ways in order to assess its validity: Verification using GHV disciplinary data, Validation using selected disciplinary analysis methods, and Application of the CMDS Composition Process to assess the design solution space for the GHV hardware. The research demonstrates the holistic effect that selection of individual disciplinary analysis methods has on the structure and integration of the analysis framework.

SNPit: a federated data integration system for the purpose of functional SNP annotation.

PubMed

Shen, Terry H; Carlson, Christopher S; Tarczy-Hornoch, Peter

2009-08-01

Genome wide association studies can potentially identify the genetic causes behind the majority of human diseases. With the advent of more advanced genotyping techniques, there is now an explosion of data gathered on single nucleotide polymorphisms (SNPs). The need exists for an integrated system that can provide up-to-date functional annotation information on SNPs. We have developed the SNP Integration Tool (SNPit) system to address this need. Built upon a federated data integration system, SNPit provides current information on a comprehensive list of SNP data sources. Additional logical inference analysis was included through an inference engine plug in. The SNPit web servlet is available online for use. SNPit allows users to go to one source for up-to-date information on the functional annotation of SNPs. A tool that can help to integrate and analyze the potential functional significance of SNPs is important for understanding the results from genome wide association studies.

Towards an integral computer environment supporting system operations analysis and conceptual design

NASA Technical Reports Server (NTRS)

Barro, E.; Delbufalo, A.; Rossi, F.

1994-01-01

VITROCISET has in house developed a prototype tool named System Dynamic Analysis Environment (SDAE) to support system engineering activities in the initial definition phase of a complex space system. The SDAE goal is to provide powerful means for the definition, analysis, and trade-off of operations and design concepts for the space and ground elements involved in a mission. For this purpose SDAE implements a dedicated modeling methodology based on the integration of different modern (static and dynamic) analysis and simulation techniques. The resulting 'system model' is capable of representing all the operational, functional, and behavioral aspects of the system elements which are part of a mission. The execution of customized model simulations enables: the validation of selected concepts with respect to mission requirements; the in-depth investigation of mission specific operational and/or architectural aspects; and the early assessment of performances required by the system elements to cope with mission constraints and objectives. Due to its characteristics, SDAE is particularly tailored for nonconventional or highly complex systems, which require a great analysis effort in their early definition stages. SDAE runs under PC-Windows and is currently used by VITROCISET system engineering group. This paper describes the SDAE main features, showing some tool output examples.

Model-Based Fault Diagnosis: Performing Root Cause and Impact Analyses in Real Time

NASA Technical Reports Server (NTRS)

Figueroa, Jorge F.; Walker, Mark G.; Kapadia, Ravi; Morris, Jonathan

2012-01-01

Generic, object-oriented fault models, built according to causal-directed graph theory, have been integrated into an overall software architecture dedicated to monitoring and predicting the health of mission- critical systems. Processing over the generic fault models is triggered by event detection logic that is defined according to the specific functional requirements of the system and its components. Once triggered, the fault models provide an automated way for performing both upstream root cause analysis (RCA), and for predicting downstream effects or impact analysis. The methodology has been applied to integrated system health management (ISHM) implementations at NASA SSC's Rocket Engine Test Stands (RETS).

Geometric Integration of Weakly Dissipative Systems

NASA Astrophysics Data System (ADS)

Modin, K.; Führer, C.; Soöderlind, G.

2009-09-01

Some problems in mechanics, e.g. in bearing simulation, contain subsystems that are conservative as well as weakly dissipative subsystems. Our experience is that geometric integration methods are often superior for such systems, as long as the dissipation is weak. Here we develop adaptive methods for dissipative perturbations of Hamiltonian systems. The methods are "geometric" in the sense that the form of the dissipative perturbation is preserved. The methods are linearly explicit, i.e., they require the solution of a linear subsystem. We sketch an analysis in terms of backward error analysis and numerical comparisons with a conventional RK method of the same order is given.

Influenza Virus Database (IVDB): an integrated information resource and analysis platform for influenza virus research.

PubMed

Chang, Suhua; Zhang, Jiajie; Liao, Xiaoyun; Zhu, Xinxing; Wang, Dahai; Zhu, Jiang; Feng, Tao; Zhu, Baoli; Gao, George F; Wang, Jian; Yang, Huanming; Yu, Jun; Wang, Jing

2007-01-01

Frequent outbreaks of highly pathogenic avian influenza and the increasing data available for comparative analysis require a central database specialized in influenza viruses (IVs). We have established the Influenza Virus Database (IVDB) to integrate information and create an analysis platform for genetic, genomic, and phylogenetic studies of the virus. IVDB hosts complete genome sequences of influenza A virus generated by Beijing Institute of Genomics (BIG) and curates all other published IV sequences after expert annotation. Our Q-Filter system classifies and ranks all nucleotide sequences into seven categories according to sequence content and integrity. IVDB provides a series of tools and viewers for comparative analysis of the viral genomes, genes, genetic polymorphisms and phylogenetic relationships. A search system has been developed for users to retrieve a combination of different data types by setting search options. To facilitate analysis of global viral transmission and evolution, the IV Sequence Distribution Tool (IVDT) has been developed to display the worldwide geographic distribution of chosen viral genotypes and to couple genomic data with epidemiological data. The BLAST, multiple sequence alignment and phylogenetic analysis tools were integrated for online data analysis. Furthermore, IVDB offers instant access to pre-computed alignments and polymorphisms of IV genes and proteins, and presents the results as SNP distribution plots and minor allele distributions. IVDB is publicly available at http://influenza.genomics.org.cn.

Health Systems Integration of Sexual and Reproductive Health and HIV Services in Sub-Saharan Africa: A Scoping Study

PubMed Central

Kendall, Tamil; Langer, Ana; Bärnighausen, Till

2014-01-01

Objective: Both sexual and reproductive health (SRH) services and HIV programs in sub-Saharan Africa are typically delivered vertically, operating parallel to national health systems. The objective of this study was to map the evidence on national and international strategies for integration of SRH and HIV services in sub-Saharan Africa and to develop a research agenda for future health systems integration. Methods: We examined the literature on national and international strategies to integrate SRH and HIV services using a scoping study methodology. Current policy frameworks, national HIV strategies and research, and gray literature on integration were mapped. Five countries in sub-Saharan Africa with experience of integrating SRH and HIV services were purposively sampled for detailed thematic analysis, according to the health systems functions of governance, policy and planning, financing, health workforce organization, service organization, and monitoring and evaluation. Results: The major international health policies and donor guidance now support integration. Most integration research has focused on linkages of SRH and HIV front-line services. Yet, the common problems with implementation are related to delayed or incomplete integration of higher level health systems functions: lack of coordinated leadership and unified national integration policies; separate financing streams for SRH and HIV services and inadequate health worker training, supervision and retention. Conclusions: Rigorous health systems research on the integration of SRH and HIV services is urgently needed. Priority research areas include integration impact, performance, and economic evaluation to inform the planning, financing, and coordination of integrated service delivery. PMID:25436826

Visit from JAXA to NASA MSFC: The Engines Element & Ideas for Collaboration

NASA Technical Reports Server (NTRS)

Greene, William D.

2013-01-01

System Design, Development, and Fabrication: Design, develop, and fabricate or procure MB-60 component hardware compliant with the imposed technical requirements and in sufficient quantities to fulfill the overall MB-60 development effort. System Development, Assembly, and Test: Manage the scope of the development, assembly, and test-related activities for MB-60 development. This scope includes engine-level development planning, engine assembly and disassembly, test planning, engine testing, inspection, anomaly resolution, and development of necessary ground support equipment and special test equipment. System Integration: Provide coordinated integration in the realms of engineering, safety, quality, and manufacturing disciplines across the scope of the MB-60 design and associated products development Safety and Mission Assurance, structural design, fracture control, materials and processes, thermal analysis. Systems Engineering and Analysis: Manage and perform Systems Engineering and Analysis to provide rigor and structure to the overall design and development effort for the MB-60. Milestone reviews, requirements management, system analysis, program management support Program Management: Manage, plan, and coordinate the activities across all portions of the MB-60 work scope by providing direction for program administration, business management, and supplier management.

Overview: Applications of numerical optimization methods to helicopter design problems

NASA Technical Reports Server (NTRS)

Miura, H.

1984-01-01

There are a number of helicopter design problems that are well suited to applications of numerical design optimization techniques. Adequate implementation of this technology will provide high pay-offs. There are a number of numerical optimization programs available, and there are many excellent response/performance analysis programs developed or being developed. But integration of these programs in a form that is usable in the design phase should be recognized as important. It is also necessary to attract the attention of engineers engaged in the development of analysis capabilities and to make them aware that analysis capabilities are much more powerful if integrated into design oriented codes. Frequently, the shortcoming of analysis capabilities are revealed by coupling them with an optimization code. Most of the published work has addressed problems in preliminary system design, rotor system/blade design or airframe design. Very few published results were found in acoustics, aerodynamics and control system design. Currently major efforts are focused on vibration reduction, and aerodynamics/acoustics applications appear to be growing fast. The development of a computer program system to integrate the multiple disciplines required in helicopter design with numerical optimization technique is needed. Activities in Britain, Germany and Poland are identified, but no published results from France, Italy, the USSR or Japan were found.

Benefit-Cost Analysis of Integrated Paratransit Systems : Volume 6. Technical Appendices.

DOT National Transportation Integrated Search

1979-09-01

This last volume, includes five technical appendices which document the methodologies used in the benefit-cost analysis. They are the following: Scenario analysis methodology; Impact estimation; Example of impact estimation; Sensitivity analysis; Agg...

Integrated Modeling Tools for Thermal Analysis and Applications

NASA Technical Reports Server (NTRS)

Milman, Mark H.; Needels, Laura; Papalexandris, Miltiadis

1999-01-01

Integrated modeling of spacecraft systems is a rapidly evolving area in which multidisciplinary models are developed to design and analyze spacecraft configurations. These models are especially important in the early design stages where rapid trades between subsystems can substantially impact design decisions. Integrated modeling is one of the cornerstones of two of NASA's planned missions in the Origins Program -- the Next Generation Space Telescope (NGST) and the Space Interferometry Mission (SIM). Common modeling tools for control design and opto-mechanical analysis have recently emerged and are becoming increasingly widely used. A discipline that has been somewhat less integrated, but is nevertheless of critical concern for high precision optical instruments, is thermal analysis and design. A major factor contributing to this mild estrangement is that the modeling philosophies and objectives for structural and thermal systems typically do not coincide. Consequently the tools that are used in these discplines suffer a degree of incompatibility, each having developed along their own evolutionary path. Although standard thermal tools have worked relatively well in the past. integration with other disciplines requires revisiting modeling assumptions and solution methods. Over the past several years we have been developing a MATLAB based integrated modeling tool called IMOS (Integrated Modeling of Optical Systems) which integrates many aspects of structural, optical, control and dynamical analysis disciplines. Recent efforts have included developing a thermal modeling and analysis capability, which is the subject of this article. Currently, the IMOS thermal suite contains steady state and transient heat equation solvers, and the ability to set up the linear conduction network from an IMOS finite element model. The IMOS code generates linear conduction elements associated with plates and beams/rods of the thermal network directly from the finite element structural model. Conductances for temperature varying materials are accommodated. This capability both streamlines the process of developing the thermal model from the finite element model, and also makes the structural and thermal models compatible in the sense that each structural node is associated with a thermal node. This is particularly useful when the purpose of the analysis is to predict structural deformations due to thermal loads. The steady state solver uses a restricted step size Newton method, and the transient solver is an adaptive step size implicit method applicable to general differential algebraic systems. Temperature dependent conductances and capacitances are accommodated by the solvers. In addition to discussing the modeling and solution methods. applications where the thermal modeling is "in the loop" with sensitivity analysis, optimization and optical performance drawn from our experiences with the Space Interferometry Mission (SIM), and the Next Generation Space Telescope (NGST) are presented.

Analysis of airframe/engine interactions in integrated flight and propulsion control

NASA Technical Reports Server (NTRS)

Schierman, John D.; Schmidt, David K.

1991-01-01

An analysis framework for the assessment of dynamic cross-coupling between airframe and engine systems from the perspective of integrated flight/propulsion control is presented. This analysis involves to determining the significance of the interactions with respect to deterioration in stability robustness and performance, as well as critical frequency ranges where problems may occur due to these interactions. The analysis illustrated here investigates both the airframe's effects on the engine control loops and the engine's effects on the airframe control loops in two case studies. The second case study involves a multi-input/multi-output analysis of the airframe. Sensitivity studies are performed on critical interactions to examine the degradations in the system's stability robustness and performance. Magnitudes of the interactions required to cause instabilities, as well as the frequencies at which the instabilities occur are recorded. Finally, the analysis framework is expanded to include control laws which contain cross-feeds between the airframe and engine systems.

Space shuttle auxiliary propulsion system design study. Phase C and E report: Storable propellants, RCS/OMS/APU integration study

NASA Technical Reports Server (NTRS)

Anglim, D. D.; Bruns, A. E.; Perryman, D. C.; Wieland, D. L.

1972-01-01

Auxiliary propulsion concepts for application to the space shuttle are compared. Both monopropellant and bipropellant earth storable reaction control systems were evaluated. The fundamental concepts evaluated were: (1) monopropellant and bipropellant systems installed integrally within the vehicle, (2) fuel systems installed modularly in nose and wing tip pods, and (3) fuel systems installed modularly in nose and fuselage pods. Numerous design variations within these three concepts were evaluated. The system design analysis and methods for implementing each of the concepts are reported.

Preliminary Design and Investigation of Integrated Compressor with Composite Material Wheel

NASA Astrophysics Data System (ADS)

Wang, Jifeng; Müller, Norbert

2012-06-01

An integrated water vapor compressor with composite material wheel is developed and strength analysis using FEM is presented. The design of wound composite material allows for integrating all rotating parts of the drive that may simply reduce to only the rotor of the electrical motor, since no drive shaft is required anymore. This design can reduce the number of parts and mass, which is convenient for engineers to maintain the compressor. The electrical motors are brushless DC motors operating through a frequency drive and apply a torque on the wheels through the materials bonded in the wheel shrouds. This system allows a large amount of compression to be produced in a multi-stage compression setup. To determine the stress and vibration characteristics of this integrated compressor, numerical analysis is carried out using FEM. The simulation result shows that the integrated compressor with composite material wheel can be used in a chiller system where water as a refrigerant.

A Scalable Data Integration and Analysis Architecture for Sensor Data of Pediatric Asthma.

PubMed

Stripelis, Dimitris; Ambite, José Luis; Chiang, Yao-Yi; Eckel, Sandrah P; Habre, Rima

2017-04-01

According to the Centers for Disease Control, in the United States there are 6.8 million children living with asthma. Despite the importance of the disease, the available prognostic tools are not sufficient for biomedical researchers to thoroughly investigate the potential risks of the disease at scale. To overcome these challenges we present a big data integration and analysis infrastructure developed by our Data and Software Coordination and Integration Center (DSCIC) of the NIBIB-funded Pediatric Research using Integrated Sensor Monitoring Systems (PRISMS) program. Our goal is to help biomedical researchers to efficiently predict and prevent asthma attacks. The PRISMS-DSCIC is responsible for collecting, integrating, storing, and analyzing real-time environmental, physiological and behavioral data obtained from heterogeneous sensor and traditional data sources. Our architecture is based on the Apache Kafka, Spark and Hadoop frameworks and PostgreSQL DBMS. A main contribution of this work is extending the Spark framework with a mediation layer, based on logical schema mappings and query rewriting, to facilitate data analysis over a consistent harmonized schema. The system provides both batch and stream analytic capabilities over the massive data generated by wearable and fixed sensors.

User-driven integrated software lives: ``Paleomag'' paleomagnetics analysis on the Macintosh

NASA Astrophysics Data System (ADS)

Jones, Craig H.

2002-12-01

"PaleoMag," a paleomagnetics analysis package originally developed for the Macintosh operating system in 1988, allows examination of demagnetization of individual samples and analysis of directional data from collections of samples. Prior to recent reinvigorated development of the software for both Macintosh and Windows, it was widely used despite not running properly on machines and operating systems sold after 1995. This somewhat surprising situation demonstrates that there is a continued need for integrated analysis software within the earth sciences, in addition to well-developed scripting and batch-mode software. One distinct advantage of software like PaleoMag is in the ability to combine quality control with analysis within a unique graphical environment. Because such demands are frequent within the earth sciences, means of nurturing the development of similar software should be found.

Is vertical integration adding value to health systems?

PubMed

Weil, T P

2000-04-01

Vertical integration is a concept used by health systems when attempting to achieve economies of scale, greater coordination of services, and improved market penetration. This article focuses on the actual outcomes of utilizing vertical integration in the health field and then compares these findings with those reported in other industries. This analysis concludes that this organizational model does not work particularly well in the health industry, as illustrated by health alliances' poor fiscal performance when they acquire physician practices or when they start their own HMO plans.

Towards adaptive and integrated management paradigms to meet the challenges of water governance.

PubMed

Halbe, J; Pahl-Wostl, C; Sendzimir, J; Adamowski, J

2013-01-01

Integrated Water Resource Management (IWRM) aims at finding practical and sustainable solutions to water resource issues. Research and practice have shown that innovative methods and tools are not sufficient to implement IWRM - the concept needs to also be integrated in prevailing management paradigms and institutions. Water governance science addresses this human dimension by focusing on the analysis of regulatory processes that influence the behavior of actors in water management systems. This paper proposes a new methodology for the integrated analysis of water resources management and governance systems in order to elicit and analyze case-specific management paradigms. It builds on the Management and Transition Framework (MTF) that allows for the examination of structures and processes underlying water management and governance. The new methodology presented in this paper combines participatory modeling and analysis of the governance system by using the MTF to investigate case-specific management paradigms. The linking of participatory modeling and research on complex management and governance systems allows for the transfer of knowledge between scientific, policy, engineering and local communities. In this way, the proposed methodology facilitates assessment and implementation of transformation processes towards IWRM that require also the adoption of adaptive management principles. A case study on flood management in the Tisza River Basin in Hungary is provided to illustrate the application of the proposed methodology.

PGSB/MIPS PlantsDB Database Framework for the Integration and Analysis of Plant Genome Data.

PubMed

Spannagl, Manuel; Nussbaumer, Thomas; Bader, Kai; Gundlach, Heidrun; Mayer, Klaus F X

2017-01-01

Plant Genome and Systems Biology (PGSB), formerly Munich Institute for Protein Sequences (MIPS) PlantsDB, is a database framework for the integration and analysis of plant genome data, developed and maintained for more than a decade now. Major components of that framework are genome databases and analysis resources focusing on individual (reference) genomes providing flexible and intuitive access to data. Another main focus is the integration of genomes from both model and crop plants to form a scaffold for comparative genomics, assisted by specialized tools such as the CrowsNest viewer to explore conserved gene order (synteny). Data exchange and integrated search functionality with/over many plant genome databases is provided within the transPLANT project.

INS integrated motion analysis for autonomous vehicle navigation

NASA Technical Reports Server (NTRS)

Roberts, Barry; Bazakos, Mike

1991-01-01

The use of inertial navigation system (INS) measurements to enhance the quality and robustness of motion analysis techniques used for obstacle detection is discussed with particular reference to autonomous vehicle navigation. The approach to obstacle detection used here employs motion analysis of imagery generated by a passive sensor. Motion analysis of imagery obtained during vehicle travel is used to generate range measurements to points within the field of view of the sensor, which can then be used to provide obstacle detection. Results obtained with an INS integrated motion analysis approach are reviewed.

A hybrid approach to device integration on a genetic analysis platform

NASA Astrophysics Data System (ADS)

Brennan, Des; Jary, Dorothee; Kurg, Ants; Berik, Evgeny; Justice, John; Aherne, Margaret; Macek, Milan; Galvin, Paul

2012-10-01

Point-of-care (POC) systems require significant component integration to implement biochemical protocols associated with molecular diagnostic assays. Hybrid platforms where discrete components are combined in a single platform are a suitable approach to integration, where combining multiple device fabrication steps on a single substrate is not possible due to incompatible or costly fabrication steps. We integrate three devices each with a specific system functionality: (i) a silicon electro-wetting-on-dielectric (EWOD) device to move and mix sample and reagent droplets in an oil phase, (ii) a polymer microfluidic chip containing channels and reservoirs and (iii) an aqueous phase glass microarray for fluorescence microarray hybridization detection. The EWOD device offers the possibility of fully integrating on-chip sample preparation using nanolitre sample and reagent volumes. A key challenge is sample transfer from the oil phase EWOD device to the aqueous phase microarray for hybridization detection. The EWOD device, waveguide performance and functionality are maintained during the integration process. An on-chip biochemical protocol for arrayed primer extension (APEX) was implemented for single nucleotide polymorphism (SNiP) analysis. The prepared sample is aspirated from the EWOD oil phase to the aqueous phase microarray for hybridization. A bench-top instrumentation system was also developed around the integrated platform to drive the EWOD electrodes, implement APEX sample heating and image the microarray after hybridization.

Integral criteria for large-scale multiple fingerprint solutions

NASA Astrophysics Data System (ADS)

Ushmaev, Oleg S.; Novikov, Sergey O.

2004-08-01

We propose the definition and analysis of the optimal integral similarity score criterion for large scale multmodal civil ID systems. Firstly, the general properties of score distributions for genuine and impostor matches for different systems and input devices are investigated. The empirical statistics was taken from the real biometric tests. Then we carry out the analysis of simultaneous score distributions for a number of combined biometric tests and primary for ultiple fingerprint solutions. The explicit and approximate relations for optimal integral score, which provides the least value of the FRR while the FAR is predefined, have been obtained. The results of real multiple fingerprint test show good correspondence with the theoretical results in the wide range of the False Acceptance and the False Rejection Rates.

Preliminary analysis of an integrated logistics system for OSSA payloads. Volume 2: OSSA integrated logistics support strategy

NASA Technical Reports Server (NTRS)

Palguta, T.; Bradley, W.; Stockton, T.

1988-01-01

The purpose is to outline an Office of Space Science and Applications (OSSA) integrated logistics support strategy that will ensure effective logistics support of OSSA payloads at an affordable life-cycle cost. Program objectives, organizational relationships, and implementation of the logistics strategy are discussed.

SysBioCube: A Data Warehouse and Integrative Data Analysis Platform Facilitating Systems Biology Studies of Disorders of Military Relevance

DTIC Science & Technology

2013-12-18

include interactive gene and methylation profiles, interactive heatmaps, cytoscape network views, integrative genomics viewer ( IGV ), and protein-protein...single chart. The website also provides an option to include multiple genes. Integrative Genomics Viewer ( IGV )1, is a high-performance desktop tool for

Lynx web services for annotations and systems analysis of multi-gene disorders.

PubMed

Sulakhe, Dinanath; Taylor, Andrew; Balasubramanian, Sandhya; Feng, Bo; Xie, Bingqing; Börnigen, Daniela; Dave, Utpal J; Foster, Ian T; Gilliam, T Conrad; Maltsev, Natalia

2014-07-01

Lynx is a web-based integrated systems biology platform that supports annotation and analysis of experimental data and generation of weighted hypotheses on molecular mechanisms contributing to human phenotypes and disorders of interest. Lynx has integrated multiple classes of biomedical data (genomic, proteomic, pathways, phenotypic, toxicogenomic, contextual and others) from various public databases as well as manually curated data from our group and collaborators (LynxKB). Lynx provides tools for gene list enrichment analysis using multiple functional annotations and network-based gene prioritization. Lynx provides access to the integrated database and the analytical tools via REST based Web Services (http://lynx.ci.uchicago.edu/webservices.html). This comprises data retrieval services for specific functional annotations, services to search across the complete LynxKB (powered by Lucene), and services to access the analytical tools built within the Lynx platform. © The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research.

Mass Spec Studio for Integrative Structural Biology

PubMed Central

Rey, Martial; Sarpe, Vladimir; Burns, Kyle; Buse, Joshua; Baker, Charles A.H.; van Dijk, Marc; Wordeman, Linda; Bonvin, Alexandre M.J.J.; Schriemer, David C.

2015-01-01

SUMMARY The integration of biophysical data from multiple sources is critical for developing accurate structural models of large multiprotein systems and their regulators. Mass spectrometry (MS) can be used to measure the insertion location for a wide range of topographically sensitive chemical probes, and such insertion data provide a rich, but disparate set of modeling restraints. We have developed a software platform that integrates the analysis of label-based MS data with protein modeling activities (Mass Spec Studio). Analysis packages can mine any labeling data from any mass spectrometer in a proteomics-grade manner, and link labeling methods with data-directed protein interaction modeling using HADDOCK. Support is provided for hydrogen/ deuterium exchange (HX) and covalent labeling chemistries, including novel acquisition strategies such as targeted HX-tandem MS (MS2) and data-independent HX-MS2. The latter permits the modeling of highly complex systems, which we demonstrate by the analysis of microtubule interactions. PMID:25242457

Application of the integral manifold method to the analysis of the spatial motion of a rigid body fixed to a cable

NASA Astrophysics Data System (ADS)

Zabolotnov, Yu. M.

2016-07-01

We analyze the spatial motion of a rigid body fixed to a cable about its center of mass when the orbital cable system is unrolling. The analysis is based on the integral manifold method, which permits separating the rigid body motion into the slow and fast components. The motion of the rigid body is studied in the case of slow variations in the cable tension force and under the action of various disturbances.We estimate the influence of the static and dynamic asymmetry of the rigid body on its spatial motion about the cable fixation point. An example of the analysis of the rigid body motion when the orbital cable system is unrolling is given for a special program of variations in the cable tension force. The conditions of applicability of the integral manifold method are analyzed.

Towards G2G: Systems of Technology Database Systems

NASA Technical Reports Server (NTRS)

Maluf, David A.; Bell, David

2005-01-01

We present an approach and methodology for developing Government-to-Government (G2G) Systems of Technology Database Systems. G2G will deliver technologies for distributed and remote integration of technology data for internal use in analysis and planning as well as for external communications. G2G enables NASA managers, engineers, operational teams and information systems to "compose" technology roadmaps and plans by selecting, combining, extending, specializing and modifying components of technology database systems. G2G will interoperate information and knowledge that is distributed across organizational entities involved that is ideal for NASA future Exploration Enterprise. Key contributions of the G2G system will include the creation of an integrated approach to sustain effective management of technology investments that supports the ability of various technology database systems to be independently managed. The integration technology will comply with emerging open standards. Applications can thus be customized for local needs while enabling an integrated management of technology approach that serves the global needs of NASA. The G2G capabilities will use NASA s breakthrough in database "composition" and integration technology, will use and advance emerging open standards, and will use commercial information technologies to enable effective System of Technology Database systems.

Fatality analysis reporting system and roadway inventory correlation.

DOT National Transportation Integrated Search

2013-01-01

In this project, we developed an integrated database to provide new analysis capabilities : for discovering correlations between roadway characteristics and the occurrence of : fatality collisions. Specifically, the aim of this data analysis project ...

Stability analysis of the phytoplankton effect model on changes in nitrogen concentration on integrated multi-trophic aquaculture systems

NASA Astrophysics Data System (ADS)

Widowati; Putro, S. P.; Silfiana

2018-05-01

Integrated Multi-Trophic Aquaculture (IMTA) is a polyculture with several biotas maintained in it to optimize waste recycling as a food source. The interaction between phytoplankton and nitrogen as waste in fish cultivation including ammonia, nitrite, and nitrate studied in the form of mathematical models. The form model is non-linear systems of differential equations with the four variables. The analytical analysis was used to study the dynamic behavior of this model. Local stability analysis is performed at the equilibrium point with the first step linearized model by using Taylor series, then determined the Jacobian matrix. If all eigenvalues have negative real parts, then the equilibrium of the system is locally asymptotic stable. Some numerical simulations were also demonstrated to verify our analytical result.

Geoinformatics 2007: data to knowledge

USGS Publications Warehouse

Brady, Shailaja R.; Sinha, A. Krishna; Gundersen, Linda C.

2007-01-01

Geoinformatics is the term used to describe a variety of efforts to promote collaboration between the computer sciences and the geosciences to solve complex scientific questions. It refers to the distributed, integrated digital information system and working environment that provides innovative means for the study of the Earth systems, as well as other planets, through use of advanced information technologies. Geoinformatics activities range from major research and development efforts creating new technologies to provide high-quality, sustained production-level services for data discovery, integration and analysis, to small, discipline-specific efforts that develop earth science data collections and data analysis tools serving the needs of individual communities. The ultimate vision of Geoinformatics is a highly interconnected data system populated with high quality, freely available data, as well as, a robust set of software for analysis, visualization, and modeling.

Computational singular perturbation analysis of stochastic chemical systems with stiffness

DOE PAGES

Wang, Lijin; Han, Xiaoying; Cao, Yanzhao; ...

2017-01-25

Computational singular perturbation (CSP) is a useful method for analysis, reduction, and time integration of stiff ordinary differential equation systems. It has found dominant utility, in particular, in chemical reaction systems with a large range of time scales at continuum and deterministic level. On the other hand, CSP is not directly applicable to chemical reaction systems at micro or meso-scale, where stochasticity plays an non-negligible role and thus has to be taken into account. In this work we develop a novel stochastic computational singular perturbation (SCSP) analysis and time integration framework, and associated algorithm, that can be used to notmore » only construct accurately and efficiently the numerical solutions to stiff stochastic chemical reaction systems, but also analyze the dynamics of the reduced stochastic reaction systems. Furthermore, the algorithm is illustrated by an application to a benchmark stochastic differential equation model, and numerical experiments are carried out to demonstrate the effectiveness of the construction.« less

Redefining What's Possible for Renewable Energy: Grid Integration

ScienceCinema

Cochran, Jaquelin; Milligan, Michael; Bloom, Aaron; Lopez, Anthony; Mai, Trieu

2018-05-16

The Energy Department's National Renewable Energy Laboratory (NREL) is spearheading engineering innovations that will help optimize the entire energy system, and the lab's analysis capabilities complement that engineering work by identifying ways to integrate renewable energy effectively and economically. This 3-minute video shows how NREL research and analysis are redefining what’s possible for renewable energy on the grid.

UAS Integration into the NAS Project

NASA Technical Reports Server (NTRS)

Bauer, Jeff

2010-01-01

The goal of the UAS Integration in the NAS Project is to contribute capabilities that reduce technical barriers related to the safety and operational challenges associated with enabling routine UAS access to the NAS This goal will be accomplished through a two-phased approach of system-level integration of key concepts, technologies and/or procedures, and demonstrations of integrated capabilities in an operationally relevant environment. Technical objectives include: PHASE 1: a) Validating the key technical areas identified by this project. System-level analyses, a State of the Art Analysis (SOAA), and a ConOps will identify the challenges and barriers preventing routine UAS access to the NAS. b) Developing a national roadmap and gap analysis identifying specific deliverables in the area of operations, procedures, and technologies that will impact future policy decisions. PHASE 2: a) Provide regulators with a methodology for developing airworthiness requirements for UAS and data to support development of certifications standards and regulatory guidance. b) Provide systems-level integrated testing of concepts and/or capabilities that address barriers to routine access to the NAS. Through simulation and flight testing, address issues including separation assurance, communications requirements, and Pilot Aircraft Interfaces (PAIs) in operationally relevant environments

Development of the engineering design integration (EDIN) system: A computer aided design development

NASA Technical Reports Server (NTRS)

Glatt, C. R.; Hirsch, G. N.

1977-01-01

The EDIN (Engineering Design Integration) System which provides a collection of hardware and software, enabling the engineer to perform man-in-the-loop interactive evaluation of aerospace vehicle concepts, was considered. Study efforts were concentrated in the following areas: (1) integration of hardware with the Univac Exec 8 System; (2) development of interactive software for the EDIN System; (3) upgrading of the EDIN technology module library to an interactive status; (4) verification of the soundness of the developing EDIN System; (5) support of NASA in design analysis studies using the EDIN System; (6) provide training and documentation in the use of the EDIN System; and (7) provide an implementation plan for the next phase of development and recommendations for meeting long range objectives.

Integration of scheduling and discrete event simulation systems to improve production flow planning

NASA Astrophysics Data System (ADS)

Krenczyk, D.; Paprocka, I.; Kempa, W. M.; Grabowik, C.; Kalinowski, K.

2016-08-01

The increased availability of data and computer-aided technologies such as MRPI/II, ERP and MES system, allowing producers to be more adaptive to market dynamics and to improve production scheduling. Integration of production scheduling and computer modelling, simulation and visualization systems can be useful in the analysis of production system constraints related to the efficiency of manufacturing systems. A integration methodology based on semi-automatic model generation method for eliminating problems associated with complexity of the model and labour-intensive and time-consuming process of simulation model creation is proposed. Data mapping and data transformation techniques for the proposed method have been applied. This approach has been illustrated through examples of practical implementation of the proposed method using KbRS scheduling system and Enterprise Dynamics simulation system.

Advanced integrated safeguards using front-end-triggering devices

DOE Office of Scientific and Technical Information (OSTI.GOV)

Howell, J.A.; Whitty, W.J.

This report addresses potential uses of front-end-triggering devices for enhanced safeguards. Such systems incorporate video surveillance as well as radiation and other sensors. Also covered in the report are integration issues and analysis techniques.

Integrated optomechanical analysis and testing software development at MIT Lincoln Laboratory

NASA Astrophysics Data System (ADS)

Stoeckel, Gerhard P.; Doyle, Keith B.

2013-09-01

Advanced analytical software capabilities are being developed to advance the design of prototypical hardware in the Engineering Division at MIT Lincoln Laboratory. The current effort is focused on the integration of analysis tools tailored to the work flow, organizational structure, and current technology demands. These tools are being designed to provide superior insight into the interdisciplinary behavior of optical systems and enable rapid assessment and execution of design trades to optimize the design of optomechanical systems. The custom software architecture is designed to exploit and enhance the functionality of existing industry standard commercial software, provide a framework for centralizing internally developed tools, and deliver greater efficiency, productivity, and accuracy through standardization, automation, and integration. Specific efforts have included the development of a feature-rich software package for Structural-Thermal-Optical Performance (STOP) modeling, advanced Line Of Sight (LOS) jitter simulations, and improved integration of dynamic testing and structural modeling.

Computational knowledge integration in biopharmaceutical research.

PubMed

Ficenec, David; Osborne, Mark; Pradines, Joel; Richards, Dan; Felciano, Ramon; Cho, Raymond J; Chen, Richard O; Liefeld, Ted; Owen, James; Ruttenberg, Alan; Reich, Christian; Horvath, Joseph; Clark, Tim

2003-09-01

An initiative to increase biopharmaceutical research productivity by capturing, sharing and computationally integrating proprietary scientific discoveries with public knowledge is described. This initiative involves both organisational process change and multiple interoperating software systems. The software components rely on mutually supporting integration techniques. These include a richly structured ontology, statistical analysis of experimental data against stored conclusions, natural language processing of public literature, secure document repositories with lightweight metadata, web services integration, enterprise web portals and relational databases. This approach has already begun to increase scientific productivity in our enterprise by creating an organisational memory (OM) of internal research findings, accessible on the web. Through bringing together these components it has also been possible to construct a very large and expanding repository of biological pathway information linked to this repository of findings which is extremely useful in analysis of DNA microarray data. This repository, in turn, enables our research paradigm to be shifted towards more comprehensive systems-based understandings of drug action.

Millimeter-Wave GaN MMIC Integration with Additive Manufacturing

NASA Astrophysics Data System (ADS)

Coffey, Michael

This thesis addresses the analysis, design, integration and test of microwave and millimeter-wave monolithic microwave integrated circuits (MMIC or MMICs). Recent and ongoing progress in semiconductor device fabrication and MMIC processing technology has pushed the upper limit in MMIC frequencies from millimeter-wave (30-300 GHz) to terahertz (300-3000 GHz). MMIC components operating at these frequencies will be used to improve the sensitivity and performance of radiometers, receivers for communication systems, passive remote sensing systems, transceivers for radar instruments and radio astronomy systems. However, a serious hurdle in the utilization of these MMIC components, and a main topic presented in this thesis, is the development and reliable fabrication of practical packaging techniques. The focus of this thesis is the investigation of first, the design and analysis of microwave and millimeter-wave GaN MMICs and second, the integration of those MMICs into usable waveguide components. The analysis, design and testing of various X-band (8-12 GHz) thru H-band (170-260 GHz) GaN MMIC power amplifier (PA or PAs), including a V-band (40-75 GHz) voltage controlled oscillator, is the majority of this work. Several PA designs utilizing high-efficiency techniques are analyzed, designed and tested. These examples include a 2nd harmonic injection amplifier, a Class-E amplifier fabricated with a GaN-on-SiC 300 GHz fT process, and an example of the applicability of supply-modulation with a Doherty power amplifier, all operating at 10 GHz. Two H-band GaN MMIC PAs are designed, one with integrated CPW-to-waveguide transitions for integration. The analysis of PA stability is especially important for wideband, high- fT devices and a new way of analyzing stability is explored and experimentally validated. Last, the challenges of integrating MMICs operating at millimeter-wave frequencies are discussed and assemblies using additive and traditional manufacturing are demonstrated.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cutler, Dylan; Frank, Stephen; Slovensky, Michelle

Rich, well-organized building performance and energy consumption data enable a host of analytic capabilities for building owners and operators, from basic energy benchmarking to detailed fault detection and system optimization. Unfortunately, data integration for building control systems is challenging and costly in any setting. Large portfolios of buildings--campuses, cities, and corporate portfolios--experience these integration challenges most acutely. These large portfolios often have a wide array of control systems, including multiple vendors and nonstandard communication protocols. They typically have complex information technology (IT) networks and cybersecurity requirements and may integrate distributed energy resources into their infrastructure. Although the challenges are significant,more » the integration of control system data has the potential to provide proportionally greater value for these organizations through portfolio-scale analytics, comprehensive demand management, and asset performance visibility. As a large research campus, the National Renewable Energy Laboratory (NREL) experiences significant data integration challenges. To meet them, NREL has developed an architecture for effective data collection, integration, and analysis, providing a comprehensive view of data integration based on functional layers. The architecture is being evaluated on the NREL campus through deployment of three pilot implementations.« less

Purdue Ionomics Information Management System. An Integrated Functional Genomics Platform1[C][W][OA

PubMed Central

Baxter, Ivan; Ouzzani, Mourad; Orcun, Seza; Kennedy, Brad; Jandhyala, Shrinivas S.; Salt, David E.

2007-01-01

The advent of high-throughput phenotyping technologies has created a deluge of information that is difficult to deal with without the appropriate data management tools. These data management tools should integrate defined workflow controls for genomic-scale data acquisition and validation, data storage and retrieval, and data analysis, indexed around the genomic information of the organism of interest. To maximize the impact of these large datasets, it is critical that they are rapidly disseminated to the broader research community, allowing open access for data mining and discovery. We describe here a system that incorporates such functionalities developed around the Purdue University high-throughput ionomics phenotyping platform. The Purdue Ionomics Information Management System (PiiMS) provides integrated workflow control, data storage, and analysis to facilitate high-throughput data acquisition, along with integrated tools for data search, retrieval, and visualization for hypothesis development. PiiMS is deployed as a World Wide Web-enabled system, allowing for integration of distributed workflow processes and open access to raw data for analysis by numerous laboratories. PiiMS currently contains data on shoot concentrations of P, Ca, K, Mg, Cu, Fe, Zn, Mn, Co, Ni, B, Se, Mo, Na, As, and Cd in over 60,000 shoot tissue samples of Arabidopsis (Arabidopsis thaliana), including ethyl methanesulfonate, fast-neutron and defined T-DNA mutants, and natural accession and populations of recombinant inbred lines from over 800 separate experiments, representing over 1,000,000 fully quantitative elemental concentrations. PiiMS is accessible at www.purdue.edu/dp/ionomics. PMID:17189337

Optical performance assessment under environmental and mechanical perturbations in large, deployable telescopes

NASA Astrophysics Data System (ADS)

Folley, Christopher; Bronowicki, Allen

2005-09-01

Prediction of optical performance for large, deployable telescopes under environmental conditions and mechanical disturbances is a crucial part of the design verification process of such instruments for all phases of design and operation: ground testing, commissioning, and on-orbit operation. A Structural-Thermal-Optical-Performance (STOP) analysis methodology is often created that integrates the output of one analysis with the input of another. The integration of thermal environment predictions with structural models is relatively well understood, while the integration of structural deformation results into optical analysis/design software is less straightforward. A Matlab toolbox has been created that effectively integrates the predictions of mechanical deformations on optical elements generated by, for example, finite element analysis, and computes optical path differences for the distorted prescription. The engine of the toolbox is the real ray-tracing algorithm that allows the optical surfaces to be defined in a single, global coordinate system thereby allowing automatic alignment of the mechanical coordinate system with the optical coordinate system. Therefore, the physical location of the optical surfaces is identical in the optical prescription and the finite element model. The application of rigid body displacements to optical surfaces, however, is more general than for use solely in STOP analysis, such as the analysis of misalignments during the commissioning process. Furthermore, all the functionality of Matlab is available for optimization and control. Since this is a new tool for use on flight programs, it has been verified against CODE V. The toolbox' functionality, to date, is described, verification results are presented, and, as an example of its utility, results of a thermal distortion analysis are presented using the James Webb Space Telescope (JWST) prescription.

Bring It to the Pitch: Combining Video and Movement Data to Enhance Team Sport Analysis.

PubMed

Stein, Manuel; Janetzko, Halldor; Lamprecht, Andreas; Breitkreutz, Thorsten; Zimmermann, Philipp; Goldlucke, Bastian; Schreck, Tobias; Andrienko, Gennady; Grossniklaus, Michael; Keim, Daniel A

2018-01-01

Analysts in professional team sport regularly perform analysis to gain strategic and tactical insights into player and team behavior. Goals of team sport analysis regularly include identification of weaknesses of opposing teams, or assessing performance and improvement potential of a coached team. Current analysis workflows are typically based on the analysis of team videos. Also, analysts can rely on techniques from Information Visualization, to depict e.g., player or ball trajectories. However, video analysis is typically a time-consuming process, where the analyst needs to memorize and annotate scenes. In contrast, visualization typically relies on an abstract data model, often using abstract visual mappings, and is not directly linked to the observed movement context anymore. We propose a visual analytics system that tightly integrates team sport video recordings with abstract visualization of underlying trajectory data. We apply appropriate computer vision techniques to extract trajectory data from video input. Furthermore, we apply advanced trajectory and movement analysis techniques to derive relevant team sport analytic measures for region, event and player analysis in the case of soccer analysis. Our system seamlessly integrates video and visualization modalities, enabling analysts to draw on the advantages of both analysis forms. Several expert studies conducted with team sport analysts indicate the effectiveness of our integrated approach.

A Mobile Food Record For Integrated Dietary Assessment*

PubMed Central

Ahmad, Ziad; Kerr, Deborah A.; Bosch, Marc; Boushey, Carol J.; Delp, Edward J.; Khanna, Nitin; Zhu, Fengqing

2017-01-01

This paper presents an integrated dietary assessment system based on food image analysis that uses mobile devices or smartphones. We describe two components of our integrated system: a mobile application and an image-based food nutrient database that is connected to the mobile application. An easy-to-use mobile application user interface is described that was designed based on user preferences as well as the requirements of the image analysis methods. The user interface is validated by user feedback collected from several studies. Food nutrient and image databases are also described which facilitates image-based dietary assessment and enable dietitians and other healthcare professionals to monitor patients dietary intake in real-time. The system has been tested and validated in several user studies involving more than 500 users who took more than 60,000 food images under controlled and community-dwelling conditions. PMID:28691119

ENFIN--A European network for integrative systems biology.

PubMed

Kahlem, Pascal; Clegg, Andrew; Reisinger, Florian; Xenarios, Ioannis; Hermjakob, Henning; Orengo, Christine; Birney, Ewan

2009-11-01

Integration of biological data of various types and the development of adapted bioinformatics tools represent critical objectives to enable research at the systems level. The European Network of Excellence ENFIN is engaged in developing an adapted infrastructure to connect databases, and platforms to enable both the generation of new bioinformatics tools and the experimental validation of computational predictions. With the aim of bridging the gap existing between standard wet laboratories and bioinformatics, the ENFIN Network runs integrative research projects to bring the latest computational techniques to bear directly on questions dedicated to systems biology in the wet laboratory environment. The Network maintains internally close collaboration between experimental and computational research, enabling a permanent cycling of experimental validation and improvement of computational prediction methods. The computational work includes the development of a database infrastructure (EnCORE), bioinformatics analysis methods and a novel platform for protein function analysis FuncNet.

Systems Analysis Programs for Hands-on Integrated Reliability Evaluations (SAPHIRE) Tutorial

DOE Office of Scientific and Technical Information (OSTI.GOV)

C. L. Smith; S. T. Beck; S. T. Wood

2008-08-01

The Systems Analysis Programs for Hands-on Integrated Reliability Evaluations (SAPHIRE) refers to a set of computer programs that were developed to create and analyze probabilistic risk assessment (PRAs). This volume is the tutorial manual for the SAPHIRE system. In this document, a series of lessons are provided that guide the user through basic steps common to most analyses preformed with SAPHIRE. The tutorial is divided into two major sections covering both basic and advanced features. The section covering basic topics contains lessons that lead the reader through development of a probabilistic hypothetical problem involving a vehicle accident, highlighting the program’smore » most fundamental features. The advanced features section contains additional lessons that expand on fundamental analysis features of SAPHIRE and provide insights into more complex analysis techniques. Together, these two elements provide an overview into the operation and capabilities of the SAPHIRE software.« less

An Integrated Nursing Management Information System: From Concept to Reality

PubMed Central

Pinkley, Connie L.; Sommer, Patricia K.

1988-01-01

This paper addresses the transition from the conceptualization of a Nursing Management Information System (NMIS) integrated and interdependent with the Hospital Information System (HIS) to its realization. Concepts of input, throughout, and output are presented to illustrate developmental strategies used to achieve nursing information products. Essential processing capabilities include: 1) ability to interact with multiple data sources; 2) database management, statistical, and graphics software packages; 3) online, batch and reporting; and 4) interactive data analysis. Challenges encountered in system construction are examined.

An integrated environment for tactical guidance research and evaluation

NASA Technical Reports Server (NTRS)

Goodrich, Kenneth H.; Mcmanus, John W.

1990-01-01

NASA-Langley's Tactical Guidance Research and Evaluation System (TGRES) constitutes an integrated environment for the development of tactical guidance algorithms and evaluating the effects of novel technologies; the modularity of the system allows easy modification or replacement of system elements in order to conduct evaluations of alternative technologies. TGRES differs from existing systems in its capitalization on AI programming techniques for guidance-logic implementation. Its ability to encompass high-fidelity, six-DOF simulation models will facilitate the analysis of complete aircraft dynamics.

NEW APPROACHES IN RISK ANALYSIS OF ENVIRONMENTAL STRESSORS TO HUMAN AND ECOLOGICAL SYSTEMS

EPA Science Inventory

We explore the application of novel techniques for improving and integrating risk analysis of environmental stressors to human and ecological systems. Environmental protection decisions are guided by risk assessments serving as tools to develop regulatory policy and other relate...

Analysis of thermodynamics of two-fuel power unit integrated with a carbon dioxide separation plant

NASA Astrophysics Data System (ADS)

Kotowicz, Janusz; Bartela, Łukasz; Mikosz, Dorota

2014-12-01

The article presents the results of thermodynamic analysis of the supercritical coal-fired power plant with gross electrical output of 900 MW and a pulverized coal boiler. This unit is integrated with the absorption-based CO2 separation installation. The heat required for carrying out the desorption process, is supplied by the system with the gas turbine. Analyses were performed for two variants of the system. In the first case, in addition to the gas turbine there is an evaporator powered by exhaust gases from the gas turbine expander. The second expanded variant assumes the application of gas turbine combined cycle with heat recovery steam generator and backpressure steam turbine. The way of determining the efficiency of electricity generation and other defined indicators to assess the energy performance of the test block was showed. The size of the gas turbine system was chosen because of the need for heat for the desorption unit, taking the value of the heat demand 4 MJ/kg CO2. The analysis results obtained for the both variants of the installation with integrated CO2 separation plant were compared with the results of the analysis of the block where the separation is not conducted.

Towards an Aero-Propulso-Servo-Elasticity Analysis of a Commercial Supersonic Transport

NASA Technical Reports Server (NTRS)

Connolly, Joseph W.; Kopasakis, George; Chwalowski, Pawel; Sanetrik, Mark D.; Carlson, Jan-Renee; Silva, Walt A.; McNamara, Jack

2016-01-01

This paper covers the development of an aero-propulso-servo-elastic (APSE) model using computational fluid dynamics (CFD) and linear structural deformations. The APSE model provides the integration of the following two previously developed nonlinear dynamic simulations: a variable cycle turbofan engine and an elastic supersonic commercial transport vehicle. The primary focus of this study is to provide a means to include relevant dynamics of a turbomachinery propulsion system into the aeroelastic studies conducted during a vehicle design, which have historically neglected propulsion effects. A high fidelity CFD tool is used here for the integration platform. The elastic vehicle neglecting the propulsion system serves as a comparison of traditional approaches to the APSE results. An overview of the methodology is presented for integrating the propulsion system and elastic vehicle. Static aeroelastic analysis comparisons between the traditional and developed APSE models for a wing tip detection indicate that the propulsion system impact on the vehicle elastic response could increase the detection by approximately ten percent.

Conceptual design and exergy analysis of an integrated structure of natural gas liquefaction and production of liquid fuels from natural gas using Fischer-Tropsch synthesis

NASA Astrophysics Data System (ADS)

Niasar, Malek Shariati; Amidpour, Majid

2018-01-01

In this paper, utilizing absorption refrigeration system as an alternative to compression refrigeration system of MFC refrigeration cycle in an integrated superstructure with the main aim of reduction in required energy is investigated. High-energy consumption in such units is reduced because of the removal of a stage of the compression system, while the possibility of using waste energy through employing of absorption refrigeration system can be provided. A superstructure including cogeneration of heating, cooling and power for LNG production and liquid fuels using Fischer-Tropsch synthesis are investigated. Exergy analysis shows that the greatest amount of exergy destruction of equipment is related to the compressors by 28.99% and the lowest exergy destruction is related to the gas turbine by 0.17%. Integrated structure has overall thermal efficiency of 90% and specific power of 0.1988 kW h/(kg LNG)-1.

Bifurcation of small limit cycles in cubic integrable systems using higher-order analysis

NASA Astrophysics Data System (ADS)

Tian, Yun; Yu, Pei

2018-05-01

In this paper, we present a method of higher-order analysis on bifurcation of small limit cycles around an elementary center of integrable systems under perturbations. This method is equivalent to higher-order Melinikov function approach used for studying bifurcation of limit cycles around a center but simpler. Attention is focused on planar cubic polynomial systems and particularly it is shown that the system studied by Żoła¸dek (1995) [24] can indeed have eleven limit cycles under perturbations at least up to 7th order. Moreover, the pattern of numbers of limit cycles produced near the center is discussed up to 39th-order perturbations, and no more than eleven limit cycles are found.

A Simple Tool for the Design and Analysis of Multiple-Reflector Antennas in a Multi-Disciplinary Environment

NASA Technical Reports Server (NTRS)

Katz, Daniel S.; Cwik, Tom; Fu, Chuigang; Imbriale, William A.; Jamnejad, Vahraz; Springer, Paul L.; Borgioli, Andrea

2000-01-01

The process of designing and analyzing a multiple-reflector system has traditionally been time-intensive, requiring large amounts of both computational and human time. At many frequencies, a discrete approximation of the radiation integral may be used to model the system. The code which implements this physical optics (PO) algorithm was developed at the Jet Propulsion Laboratory. It analyzes systems of antennas in pairs, and for each pair, the analysis can be computationally time-consuming. Additionally, the antennas must be described using a local coordinate system for each antenna, which makes it difficult to integrate the design into a multi-disciplinary framework in which there is traditionally one global coordinate system, even before considering deforming the antenna as prescribed by external structural and/or thermal factors. Finally, setting up the code to correctly analyze all the antenna pairs in the system can take a fair amount of time, and introduces possible human error. The use of parallel computing to reduce the computational time required for the analysis of a given pair of antennas has been previously discussed. This paper focuses on the other problems mentioned above. It will present a methodology and examples of use of an automated tool that performs the analysis of a complete multiple-reflector system in an integrated multi-disciplinary environment (including CAD modeling, and structural and thermal analysis) at the click of a button. This tool, named MOD Tool (Millimeter-wave Optics Design Tool), has been designed and implemented as a distributed tool, with a client that runs almost identically on Unix, Mac, and Windows platforms, and a server that runs primarily on a Unix workstation and can interact with parallel supercomputers with simple instruction from the user interacting with the client.

Integrating data from biological experiments into metabolic networks with the DBE information system.

PubMed

Borisjuk, Ljudmilla; Hajirezaei, Mohammad-Reza; Klukas, Christian; Rolletschek, Hardy; Schreiber, Falk

2005-01-01

Modern 'omics'-technologies result in huge amounts of data about life processes. For analysis and data mining purposes this data has to be considered in the context of the underlying biological networks. This work presents an approach for integrating data from biological experiments into metabolic networks by mapping the data onto network elements and visualising the data enriched networks automatically. This methodology is implemented in DBE, an information system that supports the analysis and visualisation of experimental data in the context of metabolic networks. It consists of five parts: (1) the DBE-Database for consistent data storage, (2) the Excel-Importer application for the data import, (3) the DBE-Website as the interface for the system, (4) the DBE-Pictures application for the up- and download of binary (e. g. image) files, and (5) DBE-Gravisto, a network analysis and graph visualisation system. The usability of this approach is demonstrated in two examples.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hartmann, Anja, E-mail: hartmann@ipk-gatersleben.de; Schreiber, Falk; Martin-Luther-University Halle-Wittenberg, Halle

The characterization of biological systems with respect to their behavior and functionality based on versatile biochemical interactions is a major challenge. To understand these complex mechanisms at systems level modeling approaches are investigated. Different modeling formalisms allow metabolic models to be analyzed depending on the question to be solved, the biochemical knowledge and the availability of experimental data. Here, we describe a method for an integrative analysis of the structure and dynamics represented by qualitative and quantitative metabolic models. Using various formalisms, the metabolic model is analyzed from different perspectives. Determined structural and dynamic properties are visualized in the contextmore » of the metabolic model. Interaction techniques allow the exploration and visual analysis thereby leading to a broader understanding of the behavior and functionality of the underlying biological system. The System Biology Metabolic Model Framework (SBM{sup 2} – Framework) implements the developed method and, as an example, is applied for the integrative analysis of the crop plant potato.« less

Integrating Hospital Administrative Data to Improve Health Care Efficiency and Outcomes: “The Socrates Story”

PubMed Central

Lawrence, Justin; Delaney, Conor P.

2013-01-01

Evaluation of health care outcomes has become increasingly important as we strive to improve quality and efficiency while controlling cost. Many groups feel that analysis of large datasets will be useful in optimizing resource utilization; however, the ideal blend of clinical and administrative data points has not been developed. Hospitals and health care systems have several tools to measure cost and resource utilization, but the data are often housed in disparate systems that are not integrated and do not permit multisystem analysis. Systems Outcomes and Clinical Resources AdministraTive Efficiency Software (SOCRATES) is a novel data merging, warehousing, analysis, and reporting technology, which brings together disparate hospital administrative systems generating automated or customizable risk-adjusted reports. Used in combination with standardized enhanced care pathways, SOCRATES offers a mechanism to improve the quality and efficiency of care, with the ability to measure real-time changes in outcomes. PMID:24436649

Integrating hospital administrative data to improve health care efficiency and outcomes: "the socrates story".

PubMed

Lawrence, Justin; Delaney, Conor P

2013-03-01

Evaluation of health care outcomes has become increasingly important as we strive to improve quality and efficiency while controlling cost. Many groups feel that analysis of large datasets will be useful in optimizing resource utilization; however, the ideal blend of clinical and administrative data points has not been developed. Hospitals and health care systems have several tools to measure cost and resource utilization, but the data are often housed in disparate systems that are not integrated and do not permit multisystem analysis. Systems Outcomes and Clinical Resources AdministraTive Efficiency Software (SOCRATES) is a novel data merging, warehousing, analysis, and reporting technology, which brings together disparate hospital administrative systems generating automated or customizable risk-adjusted reports. Used in combination with standardized enhanced care pathways, SOCRATES offers a mechanism to improve the quality and efficiency of care, with the ability to measure real-time changes in outcomes.

MeltMan: Optimization, Evaluation, and Universal Application of a qPCR System Integrating the TaqMan qPCR and Melting Analysis into a Single Assay

PubMed Central

Nagy, Alexander; Černíková, Lenka; Vitásková, Eliška; Křivda, Vlastimil; Dán, Ádám; Dirbáková, Zuzana; Jiřincová, Helena; Procházka, Bohumír; Sedlák, Kamil; Havlíčková, Martina

2016-01-01

In the present work, we optimised and evaluated a qPCR system integrating 6-FAM (6-carboxyfluorescein)-labelled TaqMan probes and melting analysis using the SYTO 82 (S82) DNA binding dye in a single reaction. We investigated the influence of the S82 on various TaqMan and melting analysis parameters and defined its optimal concentration. In the next step, the method was evaluated in 36 different TaqMan assays with a total of 729 paired reactions using various DNA and RNA templates, including field specimens. In addition, the melting profiles of interest were correlated with the electrophoretic patterns. We proved that the S82 is fully compatible with the FAM-TaqMan system. Further, the advantages of this approach in routine diagnostic TaqMan qPCR were illustrated with practical examples. These included solving problems with flat or other atypical amplification curves or even false negativity as a result of probe binding failure. Our data clearly show that the integration of the TaqMan qPCR and melting analysis into a single assay provides an additional control option as well as the opportunity to perform more complex analyses, get more data from the reactions, and obtain analysis results with higher confidence. PMID:27031831

Using Participatory Methods and Geographic Information Systems (GIS) to Prepare for an HIV Community-Based Trial in Vulindlela, South Africa (Project Accept-HPTN 043)

ERIC Educational Resources Information Center

Chirowodza, Admire; van Rooyen, Heidi; Joseph, Philip; Sikotoyi, Sindisiwe; Richter, Linda; Coates, Thomas

2009-01-01

Recent attempts to integrate geographic information systems (GIS) and participatory techniques, have given rise to terminologies such as "participatory GIS" and "community-integrated GIS". Although GIS was initially developed for physical geographic application, it can be used for the management and analysis of health and…

Integrated dynamic analysis simulation of space stations with controllable solar array

NASA Technical Reports Server (NTRS)

Heinrichs, J. A.; Fee, J. J.

1972-01-01

A methodology is formulated and presented for the integrated structural dynamic analysis of space stations with controllable solar arrays and non-controllable appendages. The structural system flexibility characteristics are considered in the dynamic analysis by a synthesis technique whereby free-free space station modal coordinates and cantilever appendage coordinates are inertially coupled. A digital simulation of this analysis method is described and verified by comparison of interaction load solutions with other methods of solution. Motion equations are simulated for both the zero gravity and artificial gravity (spinning) orbital conditions. Closed loop controlling dynamics for both orientation control of the arrays and attitude control of the space station are provided in the simulation by various generic types of controlling systems. The capability of the simulation as a design tool is demonstrated by utilizing typical space station and solar array structural representations and a specific structural perturbing force. Response and interaction load solutions are presented for this structural configuration and indicate the importance of using an integrated type analysis for the predictions of structural interactions.

Stakeholder Definition for Indonesian Integrated Agriculture Information System (IAIS)

NASA Astrophysics Data System (ADS)

Budi Santoso, Halim; Delima, Rosa

2017-03-01

Stakeholders plays an important roles to determine the system requirements. Stakeholders are people or organizations that has an interest to the enterprise. Timely and effective consultation of relevant stakeholders is a paramount importance in the requirements engineering process. From the research and analysis of system stakeholder finds that there are four stakeholder groups in IAIS. Stakeholder analysis is being implemented by identifying stakeholder, stakeholder category, and analysis interaction between stakeholders.

Integrated mobility measurement and notation system

NASA Technical Reports Server (NTRS)

Roebuck, J. A., Jr.

1967-01-01

System for description of movements and positions facilitates design of space suits with more mobility. This measurement and notation system gives concise and unequivocal descriptions, compatible with engineering analysis and applicable to specific needs.

A New Method for Conceptual Modelling of Information Systems

NASA Astrophysics Data System (ADS)

Gustas, Remigijus; Gustiene, Prima

Service architecture is not necessarily bound to the technical aspects of information system development. It can be defined by using conceptual models that are independent of any implementation technology. Unfortunately, the conventional information system analysis and design methods cover just a part of required modelling notations for engineering of service architectures. They do not provide effective support to maintain semantic integrity between business processes and data. Service orientation is a paradigm that can be applied for conceptual modelling of information systems. The concept of service is rather well understood in different domains. It can be applied equally well for conceptualization of organizational and technical information system components. This chapter concentrates on analysis of the differences between service-oriented modelling and object-oriented modelling. Service-oriented method is used for semantic integration of information system static and dynamic aspects.

Integration of scanned document management with the anatomic pathology laboratory information system: analysis of benefits.

PubMed

Schmidt, Rodney A; Simmons, Kim; Grimm, Erin E; Middlebrooks, Michael; Changchien, Rosy

2006-11-01

Electronic document management systems (EDMSs) have the potential to improve the efficiency of anatomic pathology laboratories. We implemented a novel but simple EDMS for scanned documents as part of our laboratory information system (AP-LIS) and collected cost-benefit data with the intention of discerning the value of such a system in general and whether integration with the AP-LIS is advantageous. We found that the direct financial benefits are modest but the indirect and intangible benefits are large. Benefits of time savings and access to data particularly accrued to pathologists and residents (3.8 h/d saved for 26 pathologists and residents). Integrating the scanned document management system (SDMS) into the AP-LIS has major advantages in terms of workflow and overall simplicity. This simple, integrated SDMS is an excellent value in a practice like ours, and many of the benefits likely apply in other practice settings.

Space Station Environment Control and Life Support System Pressure Control Pump Assembly Modeling and Analysis

NASA Technical Reports Server (NTRS)

Schunk, R. Gregory

2002-01-01

This paper presents the Modeling and Analysis of the Space Station Environment Control and Life Support System Pressure Control Pump Assembly (PCPA). The contents include: 1) Integrated PCPA/Manifold Analyses; 2) Manifold Performance Analysis; 3) PCPA Motor Heat Leak Study; and 4) Future Plans. This paper is presented in viewgraph form.

NASA Supportability Engineering Implementation Utilizing DoD Practices and Processes

NASA Technical Reports Server (NTRS)

Smith, David A.; Smith, John V.

2010-01-01

The Ares I design and development program made the determination early in the System Design Review Phase to utilize DoD ILS and LSA approach for supportability engineering as an integral part of the system engineering process. This paper is to provide a review of the overall approach to design Ares-I with an emphasis on a more affordable, supportable, and sustainable launch vehicle. Discussions will include the requirements development, design influence, support concept alternatives, ILS and LSA planning, Logistics support analyses/trades performed, LSA tailoring for NASA Ares Program, support system infrastructure identification, ILS Design Review documentation, Working Group coordination, and overall ILS implementation. At the outset, the Ares I Project initiated the development of the Integrated Logistics Support Plan (ILSP) and a Logistics Support Analysis process to provide a path forward for the management of the Ares-I ILS program and supportability analysis activities. The ILSP provide the initial planning and coordination between the Ares-I Project Elements and Ground Operation Project. The LSA process provided a system engineering approach in the development of the Ares-I supportability requirements; influence the design for supportability and development of alternative support concepts that satisfies the program operability requirements. The LSA planning and analysis results are documented in the Logistics Support Analysis Report. This document was required during the Ares-I System Design Review (SDR) and Preliminary Design Review (PDR) review cycles. To help coordinate the LSA process across the Ares-I project and between programs, the LSA Report is updated and released quarterly. A System Requirement Analysis was performed to determine the supportability requirements and technical performance measurements (TPMs). Two working groups were established to provide support in the management and implement the Ares-I ILS program, the Integrated Logistics Support Working Group (ILSWG) and the Logistics Support Analysis Record Working Group (LSARWG). The Ares I ILSWG is established to assess the requirements and conduct, evaluate analyses and trade studies associated with acquisition logistic and supportability processes and to resolve Ares I integrated logistics and supportability issues. It established a strategic collaborative alliance for coordination of Logistics Support Analysis activates in support of the integrated Ares I vehicle design and development of logistics support infrastructure. A Joint Ares I - Orion LSAR Working Group was established to: 1) Guide the development of Ares-I and Orion LSAR data and serve as a model for future Constellation programs, 2) Develop rules and assumptions that will apply across the Constellation program with regards to the program's LSAR development, and 3) Maintain the Constellation LSAR Style Guide.

BIO-Plex Information System Concept

NASA Technical Reports Server (NTRS)

Jones, Harry; Boulanger, Richard; Arnold, James O. (Technical Monitor)

1999-01-01

This paper describes a suggested design for an integrated information system for the proposed BIO-Plex (Bioregenerative Planetary Life Support Systems Test Complex) at Johnson Space Center (JSC), including distributed control systems, central control, networks, database servers, personal computers and workstations, applications software, and external communications. The system will have an open commercial computing and networking, architecture. The network will provide automatic real-time transfer of information to database server computers which perform data collection and validation. This information system will support integrated, data sharing applications for everything, from system alarms to management summaries. Most existing complex process control systems have information gaps between the different real time subsystems, between these subsystems and central controller, between the central controller and system level planning and analysis application software, and between the system level applications and management overview reporting. An integrated information system is vitally necessary as the basis for the integration of planning, scheduling, modeling, monitoring, and control, which will allow improved monitoring and control based on timely, accurate and complete data. Data describing the system configuration and the real time processes can be collected, checked and reconciled, analyzed and stored in database servers that can be accessed by all applications. The required technology is available. The only opportunity to design a distributed, nonredundant, integrated system is before it is built. Retrofit is extremely difficult and costly.

Optimal Parameter Design of Coarse Alignment for Fiber Optic Gyro Inertial Navigation System.

PubMed

Lu, Baofeng; Wang, Qiuying; Yu, Chunmei; Gao, Wei

2015-06-25

Two different coarse alignment algorithms for Fiber Optic Gyro (FOG) Inertial Navigation System (INS) based on inertial reference frame are discussed in this paper. Both of them are based on gravity vector integration, therefore, the performance of these algorithms is determined by integration time. In previous works, integration time is selected by experience. In order to give a criterion for the selection process, and make the selection of the integration time more accurate, optimal parameter design of these algorithms for FOG INS is performed in this paper. The design process is accomplished based on the analysis of the error characteristics of these two coarse alignment algorithms. Moreover, this analysis and optimal parameter design allow us to make an adequate selection of the most accurate algorithm for FOG INS according to the actual operational conditions. The analysis and simulation results show that the parameter provided by this work is the optimal value, and indicate that in different operational conditions, the coarse alignment algorithms adopted for FOG INS are different in order to achieve better performance. Lastly, the experiment results validate the effectiveness of the proposed algorithm.

A Hybrid FPGA/Tilera Compute Element for Autonomous Hazard Detection and Navigation

NASA Technical Reports Server (NTRS)

Villalpando, Carlos Y.; Werner, Robert A.; Carson, John M., III; Khanoyan, Garen; Stern, Ryan A.; Trawny, Nikolas

2013-01-01

To increase safety for future missions landing on other planetary or lunar bodies, the Autonomous Landing and Hazard Avoidance Technology (ALHAT) program is developing an integrated sensor for autonomous surface analysis and hazard determination. The ALHAT Hazard Detection System (HDS) consists of a Flash LIDAR for measuring the topography of the landing site, a gimbal to scan across the terrain, and an Inertial Measurement Unit (IMU), along with terrain analysis algorithms to identify the landing site and the local hazards. An FPGA and Manycore processor system was developed to interface all the devices in the HDS, to provide high-resolution timing to accurately measure system state, and to run the surface analysis algorithms quickly and efficiently. In this paper, we will describe how we integrated COTS components such as an FPGA evaluation board, a TILExpress64, and multi-threaded/multi-core aware software to build the HDS Compute Element (HDSCE). The ALHAT program is also working with the NASA Morpheus Project and has integrated the HDS as a sensor on the Morpheus Lander. This paper will also describe how the HDS is integrated with the Morpheus lander and the results of the initial test flights with the HDS installed. We will also describe future improvements to the HDSCE.

A hybrid FPGA/Tilera compute element for autonomous hazard detection and navigation

NASA Astrophysics Data System (ADS)

Villalpando, C. Y.; Werner, R. A.; Carson, J. M.; Khanoyan, G.; Stern, R. A.; Trawny, N.

To increase safety for future missions landing on other planetary or lunar bodies, the Autonomous Landing and Hazard Avoidance Technology (ALHAT) program is developing an integrated sensor for autonomous surface analysis and hazard determination. The ALHAT Hazard Detection System (HDS) consists of a Flash LIDAR for measuring the topography of the landing site, a gimbal to scan across the terrain, and an Inertial Measurement Unit (IMU), along with terrain analysis algorithms to identify the landing site and the local hazards. An FPGA and Manycore processor system was developed to interface all the devices in the HDS, to provide high-resolution timing to accurately measure system state, and to run the surface analysis algorithms quickly and efficiently. In this paper, we will describe how we integrated COTS components such as an FPGA evaluation board, a TILExpress64, and multi-threaded/multi-core aware software to build the HDS Compute Element (HDSCE). The ALHAT program is also working with the NASA Morpheus Project and has integrated the HDS as a sensor on the Morpheus Lander. This paper will also describe how the HDS is integrated with the Morpheus lander and the results of the initial test flights with the HDS installed. We will also describe future improvements to the HDSCE.

Working in a 'third space': a closer look at the hybridity, identity and agency of nurse practitioners.

PubMed

Chulach, Teresa; Gagnon, Marilou

2016-03-01

Nurse practitioners (NPs), as advanced practice nurses, have evolved over the years to become recognized as an important and growing trend in Canada and worldwide. In spite of sound evidence as to the effectiveness of NPs in primary care and other care settings, role implementation and integration continue to pose significant challenges. This article utilizes postcolonial theory, as articulated by Homi Bhabha, to examine and challenge traditional ideologies and structures that have shaped the development, implementation and integration of the NP role to this day. Specifically, we utilize Bhabha's concepts of third space, hybridity, identity and agency in order to further conceptualize the nurse practitioner role, to examine how the role challenges some of the inherent assumptions within the healthcare system and to explore how development of each to these concepts may prove useful in integration of nurse practitioners within the healthcare system. Our analysis casts light on the importance of a broader, power structure analysis and illustrates how colonial assumptions operating within our current healthcare system entrench, expand and re-invent, as well as mask the structures and practices that serve to impede nurse practitioner full integration and contributions. Suggestions are made for future analysis and research. © 2015 John Wiley & Sons Ltd.

Advanced Technology Lifecycle Analysis System (ATLAS)

NASA Technical Reports Server (NTRS)

O'Neil, Daniel A.; Mankins, John C.

2004-01-01

Developing credible mass and cost estimates for space exploration and development architectures require multidisciplinary analysis based on physics calculations, and parametric estimates derived from historical systems. Within the National Aeronautics and Space Administration (NASA), concurrent engineering environment (CEE) activities integrate discipline oriented analysis tools through a computer network and accumulate the results of a multidisciplinary analysis team via a centralized database or spreadsheet Each minute of a design and analysis study within a concurrent engineering environment is expensive due the size of the team and supporting equipment The Advanced Technology Lifecycle Analysis System (ATLAS) reduces the cost of architecture analysis by capturing the knowledge of discipline experts into system oriented spreadsheet models. A framework with a user interface presents a library of system models to an architecture analyst. The analyst selects models of launchers, in-space transportation systems, and excursion vehicles, as well as space and surface infrastructure such as propellant depots, habitats, and solar power satellites. After assembling the architecture from the selected models, the analyst can create a campaign comprised of missions spanning several years. The ATLAS controller passes analyst specified parameters to the models and data among the models. An integrator workbook calls a history based parametric analysis cost model to determine the costs. Also, the integrator estimates the flight rates, launched masses, and architecture benefits over the years of the campaign. An accumulator workbook presents the analytical results in a series of bar graphs. In no way does ATLAS compete with a CEE; instead, ATLAS complements a CEE by ensuring that the time of the experts is well spent Using ATLAS, an architecture analyst can perform technology sensitivity analysis, study many scenarios, and see the impact of design decisions. When the analyst is satisfied with the system configurations, technology portfolios, and deployment strategies, he or she can present the concepts to a team, which will conduct a detailed, discipline-oriented analysis within a CEE. An analog to this approach is the music industry where a songwriter creates the lyrics and music before entering a recording studio.

Analysis of integrated photovoltaic-thermal systems using solar concentrators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yusoff, M.B.

1983-01-01

An integrated photovoltaic-thermal system using solar concentrators utilizes the solar radiation spectrum in the production of electrical and thermal energy. The electrical conversion efficiency of this system decreases with increasing solar cell temperature. Since a high operating temperature is desirable to maximize the quality of thermal output of the planned integrated system, a proper choice of the operating temperature for the unit cell is of vital importance. The analysis predicts performance characteristics of the unit cell by considering the dependence of the heat generation, the heat absorption and the heat transmission on the material properties of the unit cell structure.more » An analytical model has been developed to describe the heat transport phenomena occurring in the unit cell structure. The range of applicability of the one-dimensional and the two-dimensional models, which have closed-form solutions, has been demonstrated. Parametric and design studies point out the requirements for necessary good electrical and thermal performance. A procedure utilizing functional forms of component characteristics in the form of partial coefficients of the dependent variable has been developed to design and operate the integrated system to have a desirable value of the thermal to electrical output ratio both at design and operating modes.« less