3D vision system for intelligent milking robot automation
NASA Astrophysics Data System (ADS)
Akhloufi, M. A.
2013-12-01
In a milking robot, the correct localization and positioning of milking teat cups is of very high importance. The milking robots technology has not changed since a decade and is based primarily on laser profiles for teats approximate positions estimation. This technology has reached its limit and does not allow optimal positioning of the milking cups. Also, in the presence of occlusions, the milking robot fails to milk the cow. These problems, have economic consequences for producers and animal health (e.g. development of mastitis). To overcome the limitations of current robots, we have developed a new system based on 3D vision, capable of efficiently positioning the milking cups. A prototype of an intelligent robot system based on 3D vision for real-time positioning of a milking robot has been built and tested under various conditions on a synthetic udder model (in static and moving scenarios). Experimental tests, were performed using 3D Time-Of-Flight (TOF) and RGBD cameras. The proposed algorithms permit the online segmentation of teats by combing 2D and 3D visual information. The obtained results permit the teat 3D position computation. This information is then sent to the milking robot for teat cups positioning. The vision system has a real-time performance and monitors the optimal positioning of the cups even in the presence of motion. The obtained results, with both TOF and RGBD cameras, show the good performance of the proposed system. The best performance was obtained with RGBD cameras. This latter technology will be used in future real life experimental tests.
Biomimetics in Intelligent Sensor and Actuator Automation Systems
NASA Astrophysics Data System (ADS)
Bruckner, Dietmar; Dietrich, Dietmar; Zucker, Gerhard; Müller, Brit
Intelligent machines are really an old mankind's dream. With increasing technological development, the requirements for intelligent devices also increased. However, up to know, artificial intelligence (AI) lacks solutions to the demands of truly intelligent machines that have no problems to integrate themselves into daily human environments. Current hardware with a processing power of billions of operations per second (but without any model of human-like intelligence) could not substantially contribute to the intelligence of machines when compared with that of the early AI times. There are great results, of course. Machines are able to find the shortest path between far apart cities on the map; algorithms let you find information described only by few key words. But no machine is able to get us a cup of coffee from the kitchen yet.
NASA Technical Reports Server (NTRS)
Chan, Jeffrey W.; Simpson, Carol A.
1990-01-01
Active Noise Reduction (ANR) is a new technology which can reduce the level of aircraft cockpit noise that reaches the pilot's ear while simultaneously improving the signal to noise ratio for voice communications and other information bearing sound signals in the cockpit. A miniature, ear-cup mounted ANR system was tested to determine whether speech intelligibility is better for helicopter pilots using ANR compared to a control condition of ANR turned off. Two signal to noise ratios (S/N), representative of actual cockpit conditions, were used for the ratio of the speech to cockpit noise sound pressure levels. Speech intelligibility was significantly better with ANR compared to no ANR for both S/N conditions. Variability of speech intelligibility among pilots was also significantly less with ANR. When the stock helmet was used with ANR turned off, the average PB Word speech intelligibility score was below the Normally Acceptable level. In comparison, it was above that level with ANR on in both S/N levels.
Curriculum Development for Transfer Learning in Dynamic Multiagent Settings
2016-06-01
HFO) Half field offense [19] is a subtask of Robocup simulated soccer in which a team of m offensive players try to score a goal against n defensive... players while playing on one half of a soccer field. The domain poses many challenges, including a large, continuous state and action space, coordi...case study . In RoboCup-2006: Robot Soccer World Cup X, volume 4434 of Lecture Notes in Artificial Intelligence, pages 72–85. Springer Verlag, Berlin
Optic cup segmentation from fundus images for glaucoma diagnosis.
Hu, Man; Zhu, Chenghao; Li, Xiaoxing; Xu, Yongli
2017-01-02
Glaucoma is a serious disease that can cause complete, permanent blindness, and its early diagnosis is very difficult. In recent years, computer-aided screening and diagnosis of glaucoma has made considerable progress. The optic cup segmentation from fundus images is an extremely important part for the computer-aided screening and diagnosis of glaucoma. This paper presented an automatic optic cup segmentation method that used both color difference information and vessel bends information from fundus images to determine the optic cup boundary. During the implementation of this algorithm, not only were the locations of the 2 types of information points used, but also the confidences of the information points were evaluated. In this way, the information points with higher confidence levels contributed more to the determination of the final cup boundary. The proposed method was evaluated using a public database for fundus images. The experimental results demonstrated that the cup boundaries obtained by the proposed method were more consistent than existing methods with the results obtained by ophthalmologists.
Optic cup segmentation from fundus images for glaucoma diagnosis
Hu, Man; Zhu, Chenghao; Li, Xiaoxing; Xu, Yongli
2017-01-01
ABSTRACT Glaucoma is a serious disease that can cause complete, permanent blindness, and its early diagnosis is very difficult. In recent years, computer-aided screening and diagnosis of glaucoma has made considerable progress. The optic cup segmentation from fundus images is an extremely important part for the computer-aided screening and diagnosis of glaucoma. This paper presented an automatic optic cup segmentation method that used both color difference information and vessel bends information from fundus images to determine the optic cup boundary. During the implementation of this algorithm, not only were the locations of the 2 types of information points used, but also the confidences of the information points were evaluated. In this way, the information points with higher confidence levels contributed more to the determination of the final cup boundary. The proposed method was evaluated using a public database for fundus images. The experimental results demonstrated that the cup boundaries obtained by the proposed method were more consistent than existing methods with the results obtained by ophthalmologists. PMID:27764542
NASA Astrophysics Data System (ADS)
Tadokoro, Satoshi; Kitano, Hiroaki; Takahashi, Tomoichi; Noda, Itsuki; Matsubara, Hitoshi; Shinjoh, Atsushi; Koto, Tetsuo; Takeuchi, Ikuo; Takahashi, Hironao; Matsuno, Fumitoshi; Hatayama, Mitsunori; Nobe, Jun; Shimada, Susumu
2000-07-01
This paper introduces the RoboCup-Rescue Simulation Project, a contribution to the disaster mitigation, search and rescue problem. A comprehensive urban disaster simulator is constructed on distributed computers. Heterogeneous intelligent agents such as fire fighters, victims and volunteers conduct search and rescue activities in this virtual disaster world. A real world interface integrates various sensor systems and controllers of infrastructures in the real cities with the real world. Real-time simulation is synchronized with actual disasters, computing complex relationship between various damage factors and agent behaviors. A mission-critical man-machine interface provides portability and robustness of disaster mitigation centers, and augmented-reality interfaces for rescue in real disasters. It also provides a virtual- reality training function for the public. This diverse spectrum of RoboCup-Rescue contributes to the creation of the safer social system.
The traveling salesrat: insights into the dynamics of efficient spatial navigation in the rodent
NASA Astrophysics Data System (ADS)
Watkins de Jong, Laurel; Gereke, Brian; Martin, Gerard M.; Fellous, Jean-Marc
2011-10-01
Rodent spatial navigation requires the dynamic evaluation of multiple sources of information, including visual cues, self-motion signals and reward signals. The nature of the evaluation, its dynamics and the relative weighting of the multiple information streams are largely unknown and have generated many hypotheses in the field of robotics. We use the framework of the traveling salesperson problem (TSP) to study how this evaluation may be achieved. The TSP is a classical artificial intelligence NP-hard problem that requires an agent to visit a fixed set of locations once, minimizing the total distance traveled. We show that after a few trials, rats converge on a short route between rewarded food cups. We propose that this route emerges from a series of local decisions that are derived from weighing information embedded in the context of the task. We study the relative weighting of spatial and reward information and establish that, in the conditions of this experiment, when the contingencies are not in conflict, rats choose the spatial or reward optimal solution. There was a trend toward a preference for space when the contingencies were in conflict. We also show that the spatial decision about which cup to go to next is biased by the orientation of the animal. Reward contingencies are also shown to significantly and dynamically modulate the decision-making process. This paradigm will allow for further neurophysiological studies aimed at understanding the synergistic role of brain areas involved in planning, reward processing and spatial navigation. These insights will in turn suggest new neural-like architectures for the control of mobile autonomous robots.
Hayes-Harb, Rachel; Smith, Bruce L.; Bent, Tessa; Bradlow, Ann R.
2009-01-01
This study investigated the intelligibility of native and Mandarin-accented English speech for native English and native Mandarin listeners. The word-final voicing contrast was considered (as in minimal pairs such as `cub' and `cup') in a forced-choice word identification task. For these particular talkers and listeners, there was evidence of an interlanguage speech intelligibility benefit for listeners (i.e., native Mandarin listeners were more accurate than native English listeners at identifying Mandarin-accented English words). However, there was no evidence of an interlanguage speech intelligibility benefit for talkers (i.e., native Mandarin listeners did not find Mandarin-accented English speech more intelligible than native English speech). When listener and talker phonological proficiency (operationalized as accentedness) was taken into account, it was found that the interlanguage speech intelligibility benefit for listeners held only for the low phonological proficiency listeners and low phonological proficiency speech. The intelligibility data were also considered in relation to various temporal-acoustic properties of native English and Mandarin-accented English speech in effort to better understand the properties of speech that may contribute to the interlanguage speech intelligibility benefit. PMID:19606271
Intelligent agent-based intrusion detection system using enhanced multiclass SVM.
Ganapathy, S; Yogesh, P; Kannan, A
2012-01-01
Intrusion detection systems were used in the past along with various techniques to detect intrusions in networks effectively. However, most of these systems are able to detect the intruders only with high false alarm rate. In this paper, we propose a new intelligent agent-based intrusion detection model for mobile ad hoc networks using a combination of attribute selection, outlier detection, and enhanced multiclass SVM classification methods. For this purpose, an effective preprocessing technique is proposed that improves the detection accuracy and reduces the processing time. Moreover, two new algorithms, namely, an Intelligent Agent Weighted Distance Outlier Detection algorithm and an Intelligent Agent-based Enhanced Multiclass Support Vector Machine algorithm are proposed for detecting the intruders in a distributed database environment that uses intelligent agents for trust management and coordination in transaction processing. The experimental results of the proposed model show that this system detects anomalies with low false alarm rate and high-detection rate when tested with KDD Cup 99 data set.
Intelligent Agent-Based Intrusion Detection System Using Enhanced Multiclass SVM
Ganapathy, S.; Yogesh, P.; Kannan, A.
2012-01-01
Intrusion detection systems were used in the past along with various techniques to detect intrusions in networks effectively. However, most of these systems are able to detect the intruders only with high false alarm rate. In this paper, we propose a new intelligent agent-based intrusion detection model for mobile ad hoc networks using a combination of attribute selection, outlier detection, and enhanced multiclass SVM classification methods. For this purpose, an effective preprocessing technique is proposed that improves the detection accuracy and reduces the processing time. Moreover, two new algorithms, namely, an Intelligent Agent Weighted Distance Outlier Detection algorithm and an Intelligent Agent-based Enhanced Multiclass Support Vector Machine algorithm are proposed for detecting the intruders in a distributed database environment that uses intelligent agents for trust management and coordination in transaction processing. The experimental results of the proposed model show that this system detects anomalies with low false alarm rate and high-detection rate when tested with KDD Cup 99 data set. PMID:23056036
1992-04-21
information processing than someone still learning. As such, skilled responses are less susceptible to thermal stress decrements. Based on these test data...quantity you consume. Caffeine Coffee cups Tea ____ cups Soda cans Decaffeinated Coffee cups Tea _ _ cups Soda cans Alcoholic Beer 12 oz Wine 8 oz Liquor
Inferential reasoning by exclusion in children (Homo sapiens).
Hill, Andrew; Collier-Baker, Emma; Suddendorf, Thomas
2012-08-01
The cups task is the most widely adopted forced-choice paradigm for comparative studies of inferential reasoning by exclusion. In this task, subjects are presented with two cups, one of which has been surreptitiously baited. When the empty cup is shaken or its interior shown, it is possible to infer by exclusion that the alternative cup contains the reward. The present study extends the existing body of comparative work to include human children (Homo sapiens). Like chimpanzees (Pan troglodytes) that were tested with the same equipment and near-identical procedures, children aged three to five made apparent inferences using both visual and auditory information, although the youngest children showed the least-developed ability in the auditory modality. However, unlike chimpanzees, children of all ages used causally irrelevant information in a control test designed to examine the possibility that their apparent auditory inferences were the product of contingency learning (the duplicate cups test). Nevertheless, the children's ability to reason by exclusion was corroborated by their performance on a novel verbal disjunctive syllogism test, and we found preliminary evidence consistent with the suggestion that children used their causal-logical understanding to reason by exclusion in the cups task, but subsequently treated the duplicate cups information as symbolic or communicative, rather than causal. Implications for future comparative research are discussed. 2012 APA, all rights reserved
Exclusion Performance in Dwarf Goats (Capra aegagrus hircus) and Sheep (Ovis orientalis aries)
Nawroth, Christian; von Borell, Eberhard; Langbein, Jan
2014-01-01
Using a comparative approach, we investigated the ability of dwarf goats and sheep to use direct and indirect information about the location of a food reward in an object-choice task. Subjects had to choose between two cups with only one covering a reward. Before making a choice, subjects received information about the baited (direct information) or non-baited cup (indirect information). Both goats and sheep were able to use direct information (presence of food) in the object choice task. After controlling for local enhancement, we found that goats rather than sheep were able to use indirect information (i.e., the absence of food) to find a reward. The actual test setup could not clarify whether individual goats were able to inferentially reason about the content of the baited cup when only shown the content of the non-baited cup or if they simply avoided the empty cup in that situation. As browsing species, feral and wild goats exhibit highly selective feeding behaviour compared to the rather unselective grazing sheep. The potential influence of this species-specific foraging flexibility of goats and sheep for using direct and indirect information to find a food reward is discussed in relation to a higher aversion to losses in food acquisition in goats compared to sheep. PMID:24695781
Enhancement of optic cup detection through an improved vessel kink detection framework
NASA Astrophysics Data System (ADS)
Wong, Damon W. K.; Liu, Jiang; Tan, Ngan Meng; Zhang, Zhuo; Lu, Shijian; Lim, Joo Hwee; Li, Huiqi; Wong, Tien Yin
2010-03-01
Glaucoma is a leading cause of blindness. The presence and extent of progression of glaucoma can be determined if the optic cup can be accurately segmented from retinal images. In this paper, we present a framework which improves the detection of the optic cup. First, a region of interest is obtained from the retinal fundus image, and a pallor-based preliminary cup contour estimate is determined. Patches are then extracted from the ROI along this contour. To improve the usability of the patches, adaptive methods are introduced to ensure the patches are within the optic disc and to minimize redundant information. The patches are then analyzed for vessels by an edge transform which generates pixel segments of likely vessel candidates. Wavelet, color and gradient information are used as input features for a SVM model to classify the candidates as vessel or non-vessel. Subsequently, a rigourous non-parametric method is adopted in which a bi-stage multi-resolution approach is used to probe and localize the location of kinks along the vessels. Finally, contenxtual information is used to fuse pallor and kink information to obtain an enhanced optic cup segmentation. Using a batch of 21 images obtained from the Singapore Eye Research Institute, the new method results in a 12.64% reduction in the average overlap error against a pallor only cup, indicating viable improvements in the segmentation and supporting the use of kinks for optic cup detection.
Cheng, M; Kung, R; Hannah, M; Wilansky, D; Shime, J
1995-09-01
To determine whether the menses cup is well tolerated by menstruating women. Prospective descriptive clinical study. Normal human volunteers in an academic research environment. Fifty-one menstruating women recruited between June to December 1991. Each participant was provided with two menses cups and an instruction sheet. Baseline information, including age, occupation, martial status, parity, description of menstrual flow, and current method used to cope with menstrual flow was collected. Subjects were asked to describe their experience with the cup at 1-, 2-, 6-, and 12-month intervals. The proportion of women who found the cup acceptable. The cup was used by 51 subjects for a total of 159 cycles. Overall, 23 women (45%) found the cup an acceptable method for coping with menses. Among 29 (57%) women who used the cup for two or more cycles, 62% found it acceptable. The menses cup may be an acceptable method for some women for coping with menstrual flow.
Bracher, Mike; Drosdowsky, Allison; Richardson, Alison; Symons, John; Mileshkin, Linda; Schofield, Penny
2017-01-01
Objectives To explore differences in experiences of care reported in the Cancer Patient Experience Survey (CPES) between patients with cancer of unknown primary (CUP) and those with metastatic disease of known primary (non-CUP); to determine insights pertaining to the experiences of care for CUP respondents from free-text comments. Design Two separate, but related, studies, involving secondary analysis of existing data. Using frequency matching of CUP and non-CUP patients, statistical comparisons of responses to CPES questions were conducted. Free-text comments from CUP respondents were analysed thematically. Setting and participants The CPES questionnaire comprises 63 closed questions measuring 8 areas that relate to experience of care and 3 free-text questions. Questionnaires were mailed to all adult patients (aged ≥16 years) in England with cancer admitted to hospital between 1 September 2013 and 30 November 2013. Results Matched analysis of closed response items from 2992 patients found significant differences between CUP (n=1496) and non-CUP patients (n=1496): CUP patients were more likely to want more written information about their type of cancer and tests received, to receive their diagnosis from a general practitioner (GP) and have seen allied health professionals, but less likely to have understood explanations of their condition or had surgery. Freetext responses (n=3055) were coded into 17 categories and provided deeper insight regarding patient information and interactions with GPs. CPES data may include a preponderance of patients with favourable CUP subtypes and patients initially identified as CUP but whose primary was subsequently identified. Conclusions These are the first large-scale studies to explore the experiences of care of CUP patients. The significant differences identified between the experiences of CUP and non-CUP patients suggest CUP patients require more psychosocial support and specific interventions to manage diagnostic uncertainty and the multiple investigations many CUP patients face. Substantial limitations were identified with the CPES data, emphasising the need for prospective studies. PMID:28963312
Refractories for high alkali environments
DOE Office of Scientific and Technical Information (OSTI.GOV)
Rau, A.W.; Cloer, F.
1996-12-31
Information on refractories for high alkali environments is outlined. Information is presented on: product gallery; alkali attack; chemical reactions; basic layout of alkali cup test; criteria for rating alkali cup test samples; and basic layout of physical properties test.
Developing and validating a sham cupping device.
Lee, Myeong Soo; Kim, Jong-In; Kong, Jae Cheol; Lee, Dong-Hyo; Shin, Byung-Cheul
2010-12-01
The aims of this study were to develop a sham cupping device and to validate its use as a placebo control for healthy volunteers. A sham cupping device was developed by establishing a small hole to reduce the negative pressure after suction such that inner pressure could not be maintained in the cup. We enrolled 34 healthy participants to evaluate the validity of the sham cupping device as a placebo control. The participants were informed that they would receive either real or sham cupping and were asked which treatment they thought they had received. Other sensations and adverse events related to cupping therapy were investigated. 17 patients received real cupping therapy and 17 received sham cupping. The two groups felt similar sensations. There was a tendency for subjects to feel that real cupping created a stronger sensation than sham cupping (48.9±21.4 vs 33.3±20.3 on a 100mm visual analogue scale). There were only mild to moderate adverse events observed in both groups. We developed a new sham cupping device that seems to provide a credible control for real cupping therapy by producing little or no negative pressure. This conclusion was supported by a pilot study, but more rigorous research is warranted regarding the use of this device.
Early migration characteristics of a 180° porous-coated cup with 1-mm press fit.
Stihsen, Christoph; Rath, Christopher; Radl, Roman; Saalabian, Ali A; Materna, Wilfried; Rehak, Peter; Windhager, Reinhard
2013-05-01
Evaluation of early cup movement is an important diagnostic tool to predict the likelihood of long-term implant loosening and clinical failure. The investigated cementless cup is clinically proven over 10 years, but there is a paucity of information that accurately describes the migration characteristics of this component. We retrospectively analysed the clinical outcome and migration behaviour of 60 Pinnacle 100 shells after an average 3.8-year follow-up (range 2.1-5.4 years). For migration measurement, EBRA (Einzel-Bild-Röntgen-Analyse) digital software was applied. Clinical assessment was performed using the HHS, the UCLA score and the SF-36 health survey. The clinical outcome showed excellent results with a mean HHS of 95.4 (SD 7.1) and mean UCLA of 6.9 (SD 1.3). All implants were radiologically stable within the observation period and none of the cups was at risk for aseptical loosening. EBRA analysis revealed a mean total migration of 1.4 mm (SD 0.9) (95 % CI 1.1-1.6) at 3 years. Eight cups migrated more than 1 mm within the first three postoperative months, thereafter the migration curves flattened down. Surgeons may expect to find a variable amount of early migration when using the Pinnacle cup. To our knowledge, these are the first results, which show an early "impaction" of a cementless cup, followed by subsequent osseointegration. We believe that an appropriate long-term outcome of the investigated cup is ensured. The data of the present investigation will provide clinicians with useful baseline information with which to compare new cup designs.
Song, Hyun-joo; Onishi, Kristine H.; Baillargeon, Renée; Fisher, Cynthia
2008-01-01
Do 18-month-olds understand that an agent’s false belief can be corrected by an appropriate, though not an inappropriate, communication? In Experiment 1, infants watched a series of events involving two agents, a ball, and two containers: a box and a cup. To start, agent1 played with the ball and then hid it in the box, while agent2 looked on. Next, in agent1’s absence, agent2 moved the ball from the box to the cup. When agent1 returned, agent2 told her “The ball is in the cup!” (informative-intervention condition) or “I like the cup!” (uninformative-intervention condition). During test, agent1 reached for either the box (box event) or the cup (cup event). In the informative-intervention condition, infants who saw the box event looked reliably longer than those who saw the cup event; in the uninformative-intervention condition, the reverse pattern was found. These results suggest that infants expected agent1’s false belief about the ball’s location to be corrected when she was told “The ball is in the cup!”, but not “I like the cup!”. In Experiment 2, agent2 simply pointed to the ball’s new location, and infants again expected agent1’s false belief to be corrected. These and control results provide additional evidence that infants in the second year of life can attribute false beliefs to agents. In addition, the results suggest that by 18 months of age infants expect agents’ false beliefs to be corrected by relevant communications involving words or gestures. PMID:18976745
Carcinoma of Unknown Primary Treatment (PDQ®)—Patient Version
Carcinoma of unknown primary (CUP), treatment can include surgery, radiation therapy, chemotherapy, or hormone therapy. Get detailed information about the diagnosis and treatment of CUP in this expert-reviewed summary.
Kilov, Andrea M; Togher, Leanne; Power, Emma
2015-01-01
To determine test-re-test reliability of the 'Computer User Profile' (CUP) in people with and without TBI. The CUP was administered on two occasions to people with and without TBI. The CUP investigated the nature and frequency of participants' computer and Internet use. Intra-class correlation coefficients and kappa coefficients were conducted to measure reliability of individual CUP items. Descriptive statistics were used to summarize content of responses. Sixteen adults with TBI and 40 adults without TBI were included in the study. All participants were reliable in reporting demographic information, frequency of social communication and leisure activities and computer/Internet habits and usage. Adults with TBI were reliable in 77% of their responses to survey items. Adults without TBI were reliable in 88% of their responses to survey items. The CUP was practical and valuable in capturing information about social, leisure, communication and computer/Internet habits of people with and without TBI. Adults without TBI scored more items with satisfactory reliability overall in their surveys. Future studies may include larger samples and could also include an exploration of how people with/without TBI use other digital communication technologies. This may provide further information on determining technology readiness for people with TBI in therapy programmes.
NASA Astrophysics Data System (ADS)
Tuduri, Ludovic; Harner, Tom; Blanchard, Pierrette; Li, Yi-Fan; Poissant, Laurier; Waite, Don T.; Murphy, Clair; Belzer, Wayne
This paper, and its companion (that dealt with lindane and endosulfan) review available data on the presence of currently used pesticides (CUPs) in air and precipitation in Canada, since the late 1980s. Pesticides usage/sales are also given when available. Data from local studies/initiatives, region-wide monitoring networks and remote locations are compiled to summarize atmospheric levels of different CUP classes (e.g. acid herbicides, organophosphates, "new" organochlorines, triazines, etc.) and how this varies among regions and with time. Based on this information, and other parameters not specific to Canada, knowledge gaps are identified and ideas for further research work are proposed.
Cupping for stroke rehabilitation: a systematic review.
Lee, Myeong Soo; Choi, Tae-Young; Shin, Byung-Cheul; Han, Chang-ho; Ernst, Edzard
2010-07-15
Cupping is often used for stroke rehabilitation in Asian countries. Currently, no systematic review of this topic is available. The aim of this systematic review is to summarize and critically evaluate the evidence for and against the effectiveness of cupping for stroke rehabilitation. Thirteen databases were searched from their inception through March of 2010 without language restrictions. Prospective clinical trials were included if cupping was tested as the sole treatment or as an adjunct to other conventional treatments for stroke rehabilitation. We found 43 potentially relevant articles, of which 5 studies including 3 randomized clinical trials (RCTs) and 2 uncontrolled observational studies (UOSs) met our inclusion criteria. Cupping was compared with acupuncture, electro-acupuncture and warm needling. Some superior effects of cupping were found in two of the RCTs when compared to acupuncture in hemiplegic shoulder pain and high upper-limb myodynamia after stroke. The other RCT failed to show favorable effects of cupping when compared to acupuncture and warm needling in patients with hemiplegic hand edema. The two UOSs reported favorable effects of cupping on aphasia and intractable hiccup after stroke. There are not enough trials to provide evidence for the effectiveness of cupping for stroke rehabilitation because most of the included trials compared the effects with unproven evidence and were not informative. Future RCTs seem warranted but must overcome the methodological shortcomings of the existing evidence. Copyright 2010 Elsevier B.V. All rights reserved.
Carcinoma of Unknown Primary Treatment (PDQ®)—Health Professional Version
Carcinoma of unknown primary (CUP) treatment depends on the best determination of the primary site, if possible. Treatment options may include surgery, radiation therapy, and systemic treatment. Get detailed information about diagnosis and treatment of CUP in this summary for clinicians.
Well-fixed acetabular component retention or replacement: the whys and the wherefores.
Blaha, J David
2002-06-01
Occasionally the adult reconstructive surgeon is faced with a well-fixed acetabular component that is associated with an arthroplasty problem that ordinarily would require removal and replacement of the cup. Removal of a well-fixed cup is associated with considerable morbidity in bone loss, particularly in the medial wall of the acetabulum. In such a situation, retention of the cup with exchange only of the polyethylene liner may be possible. As preparation for a prospective study, I informally reviewed my experience of cup retention or replacement in revision total hip arthroplasty. An algorithm for retaining or revising a well-fixed acetabular component is presented here. Copyright 2002, Elsevier Science (USA).
Feeding neonates by cup: A systematic review of the literature
McKinney, Christy M.; Glass, Robin P.; Coffey, Patricia; Rue, Tessa; Vaughn, Matthew G.; Cunningham, Michael
2016-01-01
Objective WHO and UNICEF recommend cup feeding for neonates unable to breastfeed in low-resource settings. In developed countries, cup feeding in lieu of bottle feeding in the neonatal period is hypothesized to improve breastfeeding outcomes for those initially unable to breastfeed. Our aim was to synthesize the entire body of evidence on cup feeding. Methods We searched domestic and international databases for original research. Our search criteria required original data on cup feeding in neonates published in English between January 1990 and December 2014. Results We identified 28 original research papers. Ten were randomized clinical trials, 7 non-randomized intervention studies, and 11 observational studies; 11 were conducted in developing country. Outcomes evaluated included physiologic stability, safety, intake, duration, spillage, weight gain, any and exclusive breastfeeding, length of hospital stay, compliance, and acceptability. Cup feeding appears to be safe though intake may be less and spillage greater relative to bottle or tube feeding. Overall, slightly higher proportions of cup fed versus bottle fed infants report any breastfeeding; a greater proportion of cup fed infants reported exclusive breastfeeding at discharge and beyond. Cup feeding increases breastfeeding in subgroups (e.g. those who intend to breastfeed or women who had a Caesarean section). Compliance and acceptability is problematic in certain settings. Conclusions Further research on long-term breastfeeding outcomes and in low-resource settings would be helpful. Research data on high risk infants (e.g. those with cleft palates) would be informative. Innovative cup feeding approaches to minimize spillage, optimize compliance, and increase breastfeeding feeding are needed. PMID:27016350
Feeding Neonates by Cup: A Systematic Review of the Literature.
McKinney, Christy M; Glass, Robin P; Coffey, Patricia; Rue, Tessa; Vaughn, Matthew G; Cunningham, Michael
2016-08-01
Objective WHO and UNICEF recommend cup feeding for neonates unable to breastfeed in low-resource settings. In developed countries, cup feeding in lieu of bottle feeding in the neonatal period is hypothesized to improve breastfeeding outcomes for those initially unable to breastfeed. Our aim was to synthesize the entire body of evidence on cup feeding. Methods We searched domestic and international databases for original research. Our search criteria required original data on cup feeding in neonates published in English between January 1990 and December 2014. Results We identified 28 original research papers. Ten were randomized clinical trials, 7 non-randomized intervention studies, and 11 observational studies; 11 were conducted in developing country. Outcomes evaluated included physiologic stability, safety, intake, duration, spillage, weight gain, any and exclusive breastfeeding, length of hospital stay, compliance, and acceptability. Cup feeding appears to be safe though intake may be less and spillage greater relative to bottle or tube feeding. Overall, slightly higher proportions of cup fed versus bottle fed infants report any breastfeeding; a greater proportion of cup fed infants reported exclusive breastfeeding at discharge and beyond. Cup feeding increases breastfeeding in subgroups (e.g. those who intend to breastfeed or women who had a Caesarean section). Compliance and acceptability is problematic in certain settings. Conclusions Further research on long-term breastfeeding outcomes and in low-resource settings would be helpful. Research data on high risk infants (e.g. those with cleft palates) would be informative. Innovative cup feeding approaches to minimize spillage, optimize compliance, and increase breastfeeding feeding are needed.
Carcinoma of Unknown Primary—Health Professional Version
Carcinoma of unknown primary (CUP) is a rare disease in which malignant cells are found in the body but the site of the primary cancer is not known. Most CUPs are adenocarcinomas, or undifferentiated tumors. Find evidence-based information on the treatment for carcinoma of unknown primary.
2012-01-18
CAPE CANAVERAL, Fla. -- In Orbiter Processing Facility-2 at NASA's Kennedy Space Center in Florida, Lord Stanley’s Cup sits in the flight deck of space shuttle Atlantis. The Stanley Cup was awarded to the Boston Bruins after winning the 2011 National Hockey League (NHL) Championship. Jeremy Jacobs, chairman and chief executive officer of Delaware North Companies and owner of the Boston Bruins, brought the cup for Kennedy and Delaware North employees to view and take photographs of. The Stanley Cup is 34 1/4 inches tall, weighs 34 1/2 pounds and is more than 100 years old. Atlantis is being prepared for public display in 2013 at the Kennedy Space Center Visitor Complex. For more information, visit http://www.nasa.gov/shuttle. Photo credit: NASA/Kim Shiflett
Elmer, John W.; Teruya, Alan T.; O'Brien, Dennis W.
1996-01-01
A tomographic technique for measuring the current density distribution in electron beams using electron beam profile data acquired from a modified Faraday cup to create an image of the current density in high and low power beams. The modified Faraday cup includes a narrow slit and is rotated by a stepper motor and can be moved in the x, y and z directions. The beam is swept across the slit perpendicular thereto and controlled by deflection coils, and the slit rotated such that waveforms are taken every few degrees form 0.degree. to 360.degree. and the waveforms are recorded by a digitizing storage oscilloscope. Two-din-tensional and three-dimensional images of the current density distribution in the beam can be reconstructed by computer tomography from this information, providing quantitative information about the beam focus and alignment.
2010-06-01
researchers outside the government to produce the kinds of algorithms and software that would easily transition into solutions for teams of autonomous ... vehicles for military scenarios. To accomplish this, we began modifying the RoboCup soccer game step-by-step to incorporate rules that simulate these
Elmer, J.W.; Teruya, A.T.; O`Brien, D.W.
1996-09-10
A tomographic technique for measuring the current density distribution in electron beams using electron beam profile data acquired from a modified Faraday cup to create an image of the current density in high and low power beams is disclosed. The modified Faraday cup includes a narrow slit and is rotated by a stepper motor and can be moved in the x, y and z directions. The beam is swept across the slit perpendicular thereto and controlled by deflection coils, and the slit rotated such that waveforms are taken every few degrees from 0{degree} to 360{degree} and the waveforms are recorded by a digitizing storage oscilloscope. Two-dimensional and three-dimensional images of the current density distribution in the beam can be reconstructed by computer tomography from this information, providing quantitative information about the beam focus and alignment. 12 figs.
Evaluation of beam tracking strategies for the THOR-CSW solar wind instrument
NASA Astrophysics Data System (ADS)
De Keyser, Johan; Lavraud, Benoit; Prech, Lubomir; Neefs, Eddy; Berkenbosch, Sophie; Beeckman, Bram; Maggiolo, Romain; Fedorov, Andrei; Baruah, Rituparna; Wong, King-Wah; Amoros, Carine; Mathon, Romain; Génot, Vincent
2017-04-01
We compare different beam tracking strategies for the Cold Solar Wind (CSW) plasma spectrometer on the ESA M4 THOR mission candidate. The goal is to intelligently select the energy and angular windows the instrument is sampling and to adapt these windows as the solar wind properties evolve, with the aim to maximize the velocity distribution acquisition rate while maintaining excellent energy and angular resolution. Using synthetic data constructed using high-cadence measurements by the Faraday cup instrument on the Spektr-R mission (30 ms resolution), we test the performance of energy beam tracking with or without angular beam tracking. The algorithm can be fed both by data acquired by the plasma spectrometer during the previous measurement cycle, or by data from another instrument, in casu the Faraday Cup (FAR) instrument foreseen on THOR. We verify how these beam tracking algorithms behave for different sizes of the energy and angular windows, and for different data integration times, in order to assess the limitations of the algorithm and to avoid situations in which the algorithm loses track of the beam.
Kim, Chong S; Hannouf, Malek B; Sarma, Sisira; Rodrigues, George B; Rogan, Peter K; Mahmud, Salaheddin M; Winquist, Eric; Brackstone, Muriel; Zaric, Gregory S
2015-11-01
Cancer of unknown primary origin (CUP) is defined by the presence of pathologically identified metastatic disease without clinical or radiological evidence of a primary tumour. Our objective was to identify incident cases of CUP in Ontario, Canada, and determine the influence of histology and sites of metastases on overall survival (OS). We used the Ontario Cancer Registry (OCR) and the Same-Day Surgery and Discharge Abstract Database (SDS/DAD) to identify patients diagnosed with CUP in Ontario between 1 January 2000, and 31 December 2005. Patient diagnostic information, including histology and survival data, was obtained from the OCR. We cross-validated CUP diagnosis and obtained additional information about metastasis through data linkage with the SDS/DAD database. OS was assessed using Cox regression models adjusting for histology and sites of metastases. We identified 3564 patients diagnosed with CUP. Patients without histologically confirmed disease (n = 1821) had a one-year OS of 10.9%, whereas patients with confirmed histology (n = 1743) had a one-year OS of 15.6%. The most common metastatic sites were in the respiratory or digestive systems (n = 1603), and the most common histology was adenocarcinoma (n = 939). Three-year survival rates were 3.5%, 5.3%, 41.6% and 3.6% among adenocarcinoma, unspecified carcinoma, squamous cell carcinoma and undifferentiated histology, respectively. Three-year survival rates were 40%, 2.4%, 8.0% and 4.6% among patients with metastases localised to lymph nodes, the respiratory or digestive systems, other specified sites, and unspecified sites, respectively. CUP patients in Ontario have a poor prognosis. Some subgroups may have better survival rates, such as patients with metastases localised to lymph nodes and patients with squamous cell histology.
Quigg, Zara; Hughes, Karen; Bellis, Mark A
2013-06-01
We explore the impact of the 2010 World Cup, held in South Africa, on levels of assault attendances to 15 emergency departments in England. The majority (70.1%) of assault attendees during the 2010 World Cup was male and aged 18-34 years (52.5%). Assault attendances increased by 37.5% on the days that England played (P 001). Preparation for major sporting events in non-host countries should include violence prevention activity. Emergency department data can be used to identify violence associated with such events and thus inform both the targeting of prevention efforts and assessments of their effectiveness.
GPU-powered model analysis with PySB/cupSODA.
Harris, Leonard A; Nobile, Marco S; Pino, James C; Lubbock, Alexander L R; Besozzi, Daniela; Mauri, Giancarlo; Cazzaniga, Paolo; Lopez, Carlos F
2017-11-01
A major barrier to the practical utilization of large, complex models of biochemical systems is the lack of open-source computational tools to evaluate model behaviors over high-dimensional parameter spaces. This is due to the high computational expense of performing thousands to millions of model simulations required for statistical analysis. To address this need, we have implemented a user-friendly interface between cupSODA, a GPU-powered kinetic simulator, and PySB, a Python-based modeling and simulation framework. For three example models of varying size, we show that for large numbers of simulations PySB/cupSODA achieves order-of-magnitude speedups relative to a CPU-based ordinary differential equation integrator. The PySB/cupSODA interface has been integrated into the PySB modeling framework (version 1.4.0), which can be installed from the Python Package Index (PyPI) using a Python package manager such as pip. cupSODA source code and precompiled binaries (Linux, Mac OS/X, Windows) are available at github.com/aresio/cupSODA (requires an Nvidia GPU; developer.nvidia.com/cuda-gpus). Additional information about PySB is available at pysb.org. paolo.cazzaniga@unibg.it or c.lopez@vanderbilt.edu. Supplementary data are available at Bioinformatics online. © The Author(s) 2017. Published by Oxford University Press.
Variety Wins: Soccer-Playing Robots and Infant Walking.
Ossmy, Ori; Hoch, Justine E; MacAlpine, Patrick; Hasan, Shohan; Stone, Peter; Adolph, Karen E
2018-01-01
Although both infancy and artificial intelligence (AI) researchers are interested in developing systems that produce adaptive, functional behavior, the two disciplines rarely capitalize on their complementary expertise. Here, we used soccer-playing robots to test a central question about the development of infant walking. During natural activity, infants' locomotor paths are immensely varied. They walk along curved, multi-directional paths with frequent starts and stops. Is the variability observed in spontaneous infant walking a "feature" or a "bug?" In other words, is variability beneficial for functional walking performance? To address this question, we trained soccer-playing robots on walking paths generated by infants during free play and tested them in simulated games of "RoboCup." In Tournament 1, we compared the functional performance of a simulated robot soccer team trained on infants' natural paths with teams trained on less varied, geometric paths-straight lines, circles, and squares. Across 1,000 head-to-head simulated soccer matches, the infant-trained team consistently beat all teams trained with less varied walking paths. In Tournament 2, we compared teams trained on different clusters of infant walking paths. The team trained with the most varied combination of path shape, step direction, number of steps, and number of starts and stops outperformed teams trained with less varied paths. This evidence indicates that variety is a crucial feature supporting functional walking performance. More generally, we propose that robotics provides a fruitful avenue for testing hypotheses about infant development; reciprocally, observations of infant behavior may inform research on artificial intelligence.
Do domestic dogs interpret pointing as a command?
Scheider, Linda; Kaminski, Juliane; Call, Josep; Tomasello, Michael
2013-05-01
Domestic dogs comprehend human gestural communication flexibly, particularly the pointing gesture. Here, we examine whether dogs interpret pointing informatively, that is, as simply providing information, or rather as a command, for example, ordering them to move to a particular location. In the first study a human pointed toward an empty cup. In one manipulation, the dog either knew or did not know that the designated cup was empty (and that the other cup actually contained the food). In another manipulation, the human (as authority) either did or did not remain in the room after pointing. Dogs ignored the human's gesture if they had better information, irrespective of the authority's presence. In the second study, we varied the level of authority of the person pointing. Sometimes this person was an adult, and sometimes a young child. Dogs followed children's pointing just as frequently as they followed adults' pointing (and ignored the dishonest pointing of both), suggesting that the level of authority did not affect their behavior. Taken together these studies suggest that dogs do not see pointing as an imperative command ordering them to a particular location. It is still not totally clear, however, if they interpret it as informative or in some other way.
Hospital preparedness in advance of the 2014 FIFA World Cup in Brazil.
Shoaf, Kimberley; Osorio de Castro, Claudia G S; Miranda, Elaine Silva
2014-08-01
Regardless of the capacity of the health care system of the host nation, mass gatherings require special planning and preparedness efforts within the health system. Brazil will host the 2014 Fédération Internationale de Football Association (FIFA) World Cup and the 2016 Olympics. This paper represents the first results from Project "Prepara Brasil," which is investigating the preparedness of the health sector and pharmaceutical services for these events. Hypothesis/Problem This study was designed to identify the efforts engaged in to prepare the health sector in Brazil for the FIFA World Cup 2014 event, as well as the 2016 Summer Olympics. Key informant interviews were conducted with representatives of both the municipality and hospital sectors in each of the 12 host cities where matches will be played. A semi-structured key informant interview guide was developed, with sections for each type of participant. One of each municipality's reference hospitals was identified and seven additional general hospitals were randomly selected from all of the inpatient facilities in each municipality. The interviewers were instructed to contact a reference hospital, and two of the other hospitals, in the jurisdiction for participation in the study. Questions were asked about plans for mass-gathering events, the interaction between hospitals and government officials in preparation for the World Cup, and their perceptions of their surge capacity to meet the potential demands generated by the presence of the World Cup events in their municipalities. In all, 11 representatives of the sampled reference hospitals, and 24 representatives of other general private and public hospitals in the municipalities, were interviewed. Most of the hospitals had some interaction with government officials in preparation for the World Cup 2014. Approximately one-third (34%) received training activities from the government. Fifty-four percent (54%) of hospitals had no specific plans for communicating with the government or other agencies during the World Cup. Approximately half (51%) had plans for surge capacity during the event, but only 27% had any surge capacity for isolation of potentially infectious patients. Overall, although there has been mention of a great deal of planning on the part of the government officials for the World Cup 2014, hospital surge to meet the potential increase in demand still falls short.
Control Model for Dampening Hand Vibrations Using Information of Internal and External Coordinates
Togo, Shunta; Kagawa, Takahiro; Uno, Yoji
2015-01-01
In the present study, we investigate a control mechanism that dampens hand vibrations. Here, we propose a control method with two components to suppress hand vibrations. The first is a passive suppression method that lowers the joint stiffness to passively dampen the hand vibrations. The second is an active suppression method that adjusts an equilibrium point based on skyhook control to actively dampen the hand vibrations. In a simulation experiment, we applied these two methods to dampen hand vibrations during the shoulder’s horizontal oscillation. We also conducted a measurement experiment wherein a subject’s shoulder was sinusoidally oscillated by a platform that generated horizontal oscillations. The results of the measurement experiments showed that the jerk of each part of the arm in a task using a cup filled with water was smaller than the shoulder jerk and that in a task with a cup filled with stones was larger than the shoulder jerk. Moreover, the amplitude of the hand trajectory in both horizontal and vertical directions was smaller in a task using a cup filled with water than in a task using a cup filled with stones. The results of the measurement experiments were accurately reproduced by the active suppression method based on skyhook control. These results suggest that humans dampen hand vibrations by controlling the equilibrium point through the information of the external workspace and the internal body state rather than by lowering joint stiffness only by using internal information. PMID:25876037
All-source Information Management and Integration for Improved Collective Intelligence Production
2011-06-01
Intelligence (ELINT) • Open Source Intelligence ( OSINT ) • Technical Intelligence (TECHINT) These intelligence disciplines produce... intelligence , measurement and signature intelligence , signals intelligence , and open - source data, in the production of intelligence . All- source intelligence ...All- Source Information Integration and Management) R&D Project 3 All- Source Intelligence
Birth weight and optic nerve head parameters.
Samarawickrama, Chameen; Huynh, Son C; Liew, Gerald; Burlutsky, George; Mitchell, Paul
2009-06-01
To assess the relationship of birth weight, birth length, and head circumference as proxy markers of intrauterine growth, cup/disc ratio, and other optic disc parameters measured using optical coherence tomography (OCT). Population-based cross sectional analysis. The Sydney Childhood Eye Study examined 2353 primarily 12-year-old children from 21 randomly selected secondary schools during 2003 to 2005. Of 2353 children examined, 2134 (90.7%) had OCT scans (Zeiss Stratus OCT, Carl Zeiss Meditec, Dublin, CA) and are included in this study. The "fast" optic disc scan protocol was used. Birth weight, birth length, and head circumference were ascertained from health records. Height and weight were measured using standardized protocols, body mass index (BMI) was defined as weight (kilograms)/ height squared (meters), and sociodemographic information was collected in a questionnaire completed by parents. Low birth weight was defined as birth weight
Ogawa, Hiroyuki; Hasegawa, Seiichirou; Tsukada, Sachiyuki; Matsubara, Masaaki
2018-06-01
We developed an acetabular cup placement device, the AR-HIP system, using augmented reality (AR). The AR-HIP system allows the surgeon to view an acetabular cup image superimposed in the surgical field through a smartphone. The smartphone also shows the placement angle of the acetabular cup. This preliminary study was performed to assess the accuracy of the AR-HIP system for acetabular cup placement during total hip arthroplasty (THA). We prospectively measured the placement angles using both a goniometer and AR-HIP system in 56 hips of 54 patients undergoing primary THA. We randomly determined the order of intraoperative measurement using the 2 devices. At 3 months after THA, the placement angle of the acetabular cup was measured on computed tomography images. The primary outcome was the absolute value of the difference between intraoperative and postoperative computed tomography measurements. The measurement angle using AR-HIP was significantly more accurate in terms of radiographic anteversion than that using a goniometer (2.7° vs 6.8°, respectively; mean difference 4.1°; 95% confidence interval, 3.0-5.2; P < .0001). There was no statistically significant difference in terms of radiographic inclination (2.1° vs 2.6°; mean difference 0.5°; 95% confidence interval, -1.1 to 0.1; P = .13). In this pilot study, the AR-HIP system provided more accurate information regarding acetabular cup placement angle than the conventional method. Further studies are required to confirm the utility of the AR-HIP system as a navigation tool. Copyright © 2018 Elsevier Inc. All rights reserved.
Computer aided system for parametric design of combination die
NASA Astrophysics Data System (ADS)
Naranje, Vishal G.; Hussein, H. M. A.; Kumar, S.
2017-09-01
In this paper, a computer aided system for parametric design of combination dies is presented. The system is developed using knowledge based system technique of artificial intelligence. The system is capable to design combination dies for production of sheet metal parts having punching and cupping operations. The system is coded in Visual Basic and interfaced with AutoCAD software. The low cost of the proposed system will help die designers of small and medium scale sheet metal industries for design of combination dies for similar type of products. The proposed system is capable to reduce design time and efforts of die designers for design of combination dies.
Winter, Werner; Karl, Matthias
2014-10-01
Acetabular cup endoprostheses are frequently placed in pelvic bone, employing the mechanical principle of press fit. While a sufficiently stable bone-implant connection is desirable, deformation of the cup and fracture of the pelvis should be avoided. The goal of this work is to demonstrate the importance of the elastic properties of bone on the amount of press fit achievable in a specific situation. On the basis of previous work describing the relation between relative bone mineral density and relative elastic modulus for cortical and trabecular bone, mechanical equations were used for analyzing the press-fit loading situation of an acetabular cup. Additionally, a two-dimensional finite element model was used for visualizing the stress and strain situation in the host bone occurring as a consequence of implant insertion, as well as the effect of moment loads acting on the acetabular cup. Given the fact that oversizing the implant for a specific recipient site is the only clinical means of optimizing press fit, knowledge of the elastic properties of the host bone before implant selection would be beneficial. Such information could, for instance, be derived from intraoperative compressive testing of the host bone.
Kovács, Ágnes M.; Téglás, Ernő; Gergely, György; Csibra, Gergely
2016-01-01
In their first years, infants acquire an incredible amount of information regarding the objects present in their environment. While often it is not clear what specific information should be prioritized in encoding from the many characteristics of an object, different types of object representations facilitate different types of generalizations. We tested the hypotheses that one-year-old infants distinctively represent familiar objects as exemplars of their kind, and that ostensive communication plays a role in determining kind membership for ambiguous objects. In the training phase of our experiment, infants were exposed to movies displaying an agent sorting objects from two categories (cups and plates) into two locations (left or right). Afterwards, different groups of infants saw either an ostensive or a non-ostensive demonstration performed by the agent revealing that a new object that looked like a plate can be transformed into a cup. A third group of infants experienced no demonstration regarding the new object. During test, infants were presented with the ambiguous object in the plate format, and we measured generalization by coding anticipatory looks to the plate or the cup side. While infants looked equally often towards the two sides when the demonstration was non-ostensive, and more often to the plate side when there was no demonstration, they performed more anticipatory eye movements to the cup side when the demonstration was ostensive. Thus, ostensive demonstration likely highlighted the hidden dispositional properties of the target object as kind-relevant, guiding infants’ categorization of the foldable cup as a cup, despite that it looked like a plate. These results suggest that infants likely encode familiar objects as exemplars of their kind and that ostensive communication can play a crucial role in disambiguating what kind an object belongs to, even when this requires disregarding salient surface features. PMID:29076269
Information for the user in design of intelligent systems
NASA Technical Reports Server (NTRS)
Malin, Jane T.; Schreckenghost, Debra L.
1993-01-01
Recommendations are made for improving intelligent system reliability and usability based on the use of information requirements in system development. Information requirements define the task-relevant messages exchanged between the intelligent system and the user by means of the user interface medium. Thus, these requirements affect the design of both the intelligent system and its user interface. Many difficulties that users have in interacting with intelligent systems are caused by information problems. These information problems result from the following: (1) not providing the right information to support domain tasks; and (2) not recognizing that using an intelligent system introduces new user supervisory tasks that require new types of information. These problems are especially prevalent in intelligent systems used for real-time space operations, where data problems and unexpected situations are common. Information problems can be solved by deriving information requirements from a description of user tasks. Using information requirements embeds human-computer interaction design into intelligent system prototyping, resulting in intelligent systems that are more robust and easier to use.
32 CFR 2001.33 - Mandatory review for declassification.
Code of Federal Regulations, 2010 CFR
2010-07-01
... information sought with a reasonable amount of effort. Requests for broad types of information, entire file... information pertains to intelligence activities, the Director of National Intelligence. (d) Intelligence information. Mandatory declassification review requests for information pertaining to intelligence sources...
[Innovation of characteristic medicinal cupping devices].
Li, Jianping; Zhang, Hui; Yang, Jianmei; Xu, Xinchun; Niu, Yanxia; Cai, Jun
2015-08-01
To compare the differences in the characteristic medicinal cupping therapy between the traditional cupping device and the innovated cupping device. Fifty patients of neck and low back pain were selected. The self-comparison was adopted. The cupping therapy was applied to the acupoints located on the left or right side with the traditional cupping device and the innovated cupping device. The cupping sites were centered at bilateral Quyuan (SI 13) and Dachangshu (BL 25). The cups were retained for 10 min. The traditional cupping device was the glass with smooth border, 100mL. The innovated cupping device was the vacuum-sucking cup. The operative time, medicinal leakage, comfort and cupping marks were observed for the two different cupping devices. The operative time with the innovated medicinal cupping device was shorter obviously compared with the traditional one at Quyuan (SI 13) and Dachangshu (BL 25, both P<0. 05). The comfort with the innovated medicinal cupping device was remarkably improved as compared with the traditional one at the two acupoints (both P<0. 05). The medicinal leakage was similar between the two different devices during the cupping operation (both P>0. 05). The cupping marks with the innovated medicinal cupping device were much deeper than those with the traditional one after cupping therapy. The innovated cupping device is more convenent and comfortable in operation during the characteristic medicinal cupping therapy.
NASA Technical Reports Server (NTRS)
Myers, William; Winter, Steve
2006-01-01
The General Electric Reliable and Affordable Controls effort under the NASA Advanced Subsonic Technology (AST) Program has designed, fabricated, and tested advanced controls hardware and software to reduce emissions and improve engine safety and reliability. The original effort consisted of four elements: 1) a Hydraulic Multiplexer; 2) Active Combustor Control; 3) a Variable Displacement Vane Pump (VDVP); and 4) Intelligent Engine Control. The VDVP and Intelligent Engine Control elements were cancelled due to funding constraints and are reported here only to the state they progressed. The Hydraulic Multiplexing element developed and tested a prototype which improves reliability by combining the functionality of up to 16 solenoids and servo-valves into one component with a single electrically powered force motor. The Active Combustor Control element developed intelligent staging and control strategies for low emission combustors. This included development and tests of a Controlled Pressure Fuel Nozzle for fuel sequencing, a Fuel Multiplexer for individual fuel cup metering, and model-based control logic. Both the Hydraulic Multiplexer and Controlled Pressure Fuel Nozzle system were cleared for engine test. The Fuel Multiplexer was cleared for combustor rig test which must be followed by an engine test to achieve full maturation.
[Clinical value of cupping spot effect].
Ji, Chang-Chun; Huang, Li-Ping; Yang, Gai-Qin; Zhao, Jing-Yu; Zou, Wei; Guo, Xiao-Chuan; Liu, Shao-Ming
2014-12-01
The cupping spot is considered as one kind of skin change due to cupping treatment. With literature regarding cupping spot, the influencing factors and value of cupping spot in clinical diagnosis and treatment were analyzed, which could make a further exploration on the action mechanism of cupping treatment. The literature showed that the formation of cupping spot was related with cupping temperature, pressure, cup-retaining time, cupping area, individual difference and health condition, etc; cupping spot had the ability to assist diagnosis, prevent disease, cure disease and evaluate clinical efficacy. Previous studies on cupping spot have already made some progress, and played a positive significance on finding cupping rule and studying its mechanism. However, the research for this area is still in the primary stage, which needed deeper study to reveal scientific connotations of cupping spot.
Predictors of three-dimensional breast kinematics during bare-breasted running.
Wood, Louise Ellen; White, Jennifer; Milligan, Alexandra; Ayres, Bessie; Hedger, Wendy; Scurr, Joanna
2012-07-01
This study aimed to analyze differences in breast kinematics between breast cup sizes during running and the ability of breast and body size measurements to explain these differences. Forty-eight women (A to G cup; mean ± SD: age = 26.0 ± 6.0 yr, stature = 1.667 ± 0.064 m, mass = 62.78 ± 8.24 kg) with chest sizes of 32 to 38 inches participated. Chest and breast girths, a restricted anthropometric profile, suprasternal notch to nipple distances, and body mass index were measured, and breast mass was estimated. Multiplanar relative breast displacement, velocity, and acceleration during treadmill running were then recorded. Differences in breast kinematics were compared between cup sizes before and after allometric/polynomial scaling using significant breast and body size measures. All kinematic variables significantly increased with breast cup size (P < 0.05). Mean anterior-posterior (a/p), medial-lateral (m/l), and vertical bare-breasted displacements ranged from 0.030 to 0.059 m, from 0.018 to 0.062 m, and from 0.042 to 0.099 m, respectively, across A to G cups. Breast velocities ranged from 0.428 to 1.244 m·s(-1) (a/p), 0.411 to 1.708 m·s(-1)(m/l), and 0.819 to 2.174 m·s(-1) (vertical), respectively. Increases in breast acceleration varied from 11.664 to 48.438 m·s(-1) (a/p), 15.572 to 51.987 m·s(-1) (m/l), and 23.301 to 66.447 m·s(-1) (vertical), respectively. Scaling models found that breast mass was the only anthropometric measure to consistently explain differences in breast kinematics between cup sizes. Bare-breasted kinematics significantly increased with cup size during running. Differences in breast displacement, velocity, and acceleration between cup sizes could be predicted using estimates of breast mass based on conventional brassiere sizing. These data inform the design and evaluation of effective bra support.
Information Foraging Theory: A Framework for Intelligence Analysis
2014-11-01
oceanographic information, human intelligence (HUMINT), open-source intelligence ( OSINT ), and information provided by other governmental departments [1][5...Human Intelligence IFT Information Foraging Theory LSA Latent Semantic Similarity MVT Marginal Value Theorem OFT Optimal Foraging Theory OSINT
Histogram-driven cupping correction (HDCC) in CT
NASA Astrophysics Data System (ADS)
Kyriakou, Y.; Meyer, M.; Lapp, R.; Kalender, W. A.
2010-04-01
Typical cupping correction methods are pre-processing methods which require either pre-calibration measurements or simulations of standard objects to approximate and correct for beam hardening and scatter. Some of them require the knowledge of spectra, detector characteristics, etc. The aim of this work was to develop a practical histogram-driven cupping correction (HDCC) method to post-process the reconstructed images. We use a polynomial representation of the raw-data generated by forward projection of the reconstructed images; forward and backprojection are performed on graphics processing units (GPU). The coefficients of the polynomial are optimized using a simplex minimization of the joint entropy of the CT image and its gradient. The algorithm was evaluated using simulations and measurements of homogeneous and inhomogeneous phantoms. For the measurements a C-arm flat-detector CT (FD-CT) system with a 30×40 cm2 detector, a kilovoltage on board imager (radiation therapy simulator) and a micro-CT system were used. The algorithm reduced cupping artifacts both in simulations and measurements using a fourth-order polynomial and was in good agreement to the reference. The minimization algorithm required less than 70 iterations to adjust the coefficients only performing a linear combination of basis images, thus executing without time consuming operations. HDCC reduced cupping artifacts without the necessity of pre-calibration or other scan information enabling a retrospective improvement of CT image homogeneity. However, the method can work with other cupping correction algorithms or in a calibration manner, as well.
Variety Wins: Soccer-Playing Robots and Infant Walking
Ossmy, Ori; Hoch, Justine E.; MacAlpine, Patrick; Hasan, Shohan; Stone, Peter; Adolph, Karen E.
2018-01-01
Although both infancy and artificial intelligence (AI) researchers are interested in developing systems that produce adaptive, functional behavior, the two disciplines rarely capitalize on their complementary expertise. Here, we used soccer-playing robots to test a central question about the development of infant walking. During natural activity, infants' locomotor paths are immensely varied. They walk along curved, multi-directional paths with frequent starts and stops. Is the variability observed in spontaneous infant walking a “feature” or a “bug?” In other words, is variability beneficial for functional walking performance? To address this question, we trained soccer-playing robots on walking paths generated by infants during free play and tested them in simulated games of “RoboCup.” In Tournament 1, we compared the functional performance of a simulated robot soccer team trained on infants' natural paths with teams trained on less varied, geometric paths—straight lines, circles, and squares. Across 1,000 head-to-head simulated soccer matches, the infant-trained team consistently beat all teams trained with less varied walking paths. In Tournament 2, we compared teams trained on different clusters of infant walking paths. The team trained with the most varied combination of path shape, step direction, number of steps, and number of starts and stops outperformed teams trained with less varied paths. This evidence indicates that variety is a crucial feature supporting functional walking performance. More generally, we propose that robotics provides a fruitful avenue for testing hypotheses about infant development; reciprocally, observations of infant behavior may inform research on artificial intelligence. PMID:29867427
Yang, Xiaofeng; Wu, Shengyong; Sechopoulos, Ioannis; Fei, Baowei
2012-10-01
To develop and test an automated algorithm to classify the different tissues present in dedicated breast CT images. The original CT images are first corrected to overcome cupping artifacts, and then a multiscale bilateral filter is used to reduce noise while keeping edge information on the images. As skin and glandular tissues have similar CT values on breast CT images, morphologic processing is used to identify the skin mask based on its position information. A modified fuzzy C-means (FCM) classification method is then used to classify breast tissue as fat and glandular tissue. By combining the results of the skin mask with the FCM, the breast tissue is classified as skin, fat, and glandular tissue. To evaluate the authors' classification method, the authors use Dice overlap ratios to compare the results of the automated classification to those obtained by manual segmentation on eight patient images. The correction method was able to correct the cupping artifacts and improve the quality of the breast CT images. For glandular tissue, the overlap ratios between the authors' automatic classification and manual segmentation were 91.6% ± 2.0%. A cupping artifact correction method and an automatic classification method were applied and evaluated for high-resolution dedicated breast CT images. Breast tissue classification can provide quantitative measurements regarding breast composition, density, and tissue distribution.
Yang, Xiaofeng; Wu, Shengyong; Sechopoulos, Ioannis; Fei, Baowei
2012-01-01
Purpose: To develop and test an automated algorithm to classify the different tissues present in dedicated breast CT images. Methods: The original CT images are first corrected to overcome cupping artifacts, and then a multiscale bilateral filter is used to reduce noise while keeping edge information on the images. As skin and glandular tissues have similar CT values on breast CT images, morphologic processing is used to identify the skin mask based on its position information. A modified fuzzy C-means (FCM) classification method is then used to classify breast tissue as fat and glandular tissue. By combining the results of the skin mask with the FCM, the breast tissue is classified as skin, fat, and glandular tissue. To evaluate the authors’ classification method, the authors use Dice overlap ratios to compare the results of the automated classification to those obtained by manual segmentation on eight patient images. Results: The correction method was able to correct the cupping artifacts and improve the quality of the breast CT images. For glandular tissue, the overlap ratios between the authors’ automatic classification and manual segmentation were 91.6% ± 2.0%. Conclusions: A cupping artifact correction method and an automatic classification method were applied and evaluated for high-resolution dedicated breast CT images. Breast tissue classification can provide quantitative measurements regarding breast composition, density, and tissue distribution. PMID:23039675
A Fundamental Study of Stretch-Drawing Process of Sheet Metals : Single and Double Operations
NASA Astrophysics Data System (ADS)
Gotoh, Manabu; Kim, Young-soo; Yamashita, Minoru
1998-05-01
Fundamental and informative data of axisymmetric stretch-drawing of several sheet metals with thichness of 0.7 1.0 mm are presented especially for single and double operations. Very small radius is applied to the die-profile (or -shoulder) in all operations to induce wall-thinning by the effect of bending-under-tension, from which the name `stretch-drawing' comes. It is clearly demonstrated that deeper cups could be formed by the single and double stretch-drawings from smaller cirlcular blanks due to such wall-thinning action than in the usual deep-drawing of larger blanks. From this fact, it is emphasized that the deep-drawability of a sheet metal is not evaluated simply by the conventional LDR (=limiting drawing ratio), but the depth of the drawn cup should also be taken into account. Many experimental data about various metals and thicknesses given in this paper offer a valueable information on this process for more general use which recommends to replace the conventional deep-drawing process by the stretch-drawing process both for single and double operations. In the single stretch-drawing, it is also confirmed that a deeper cup can be produced by raising the blank-holding force at later stage of operation. Fracturing is found to occur at the middle section of the wall part or at the die-profile other than at the punch profile common in the usual deep-drawing process. Numerical simulation of the single stretch-drawing process is also performed by use of DYNA-3D code to confirm that a satisfactory prediction especially in the depth of the drawn-cup can be done at least in a practical sense, although this kind of numerical analysis is very difficult because of the severity or localization of deformation around the die profile. The drawn cup of SUS304 among others fractures in a couple of weeks after the operation due to the residual circumferential tensile stress, whereas that of SUS304L does not. In the double stretch-drawing, it is confirmed that very deeper cups can be produced when compared to the usual re-drawing process, which assures typically the usefulness of this operation as a practical process. Fracture often takes place circumferentially or, very peculiarly, even in a spiral mode for SUS304 at the middle of the wall part of the cup.
32 CFR 635.5 - Police Intelligence/Criminal Information.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 32 National Defense 4 2011-07-01 2011-07-01 false Police Intelligence/Criminal Information. 635.5... Intelligence/Criminal Information. (a) The purpose of gathering police intelligence is to identify individuals.... If police intelligence is developed to the point where it factually establishes a criminal offense...
32 CFR 635.5 - Police Intelligence/Criminal Information.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 32 National Defense 4 2012-07-01 2011-07-01 true Police Intelligence/Criminal Information. 635.5... Intelligence/Criminal Information. (a) The purpose of gathering police intelligence is to identify individuals.... If police intelligence is developed to the point where it factually establishes a criminal offense...
32 CFR 635.5 - Police Intelligence/Criminal Information.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 32 National Defense 4 2010-07-01 2010-07-01 true Police Intelligence/Criminal Information. 635.5... Intelligence/Criminal Information. (a) The purpose of gathering police intelligence is to identify individuals.... If police intelligence is developed to the point where it factually establishes a criminal offense...
32 CFR 635.5 - Police Intelligence/Criminal Information.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 32 National Defense 4 2014-07-01 2013-07-01 true Police Intelligence/Criminal Information. 635.5... Intelligence/Criminal Information. (a) The purpose of gathering police intelligence is to identify individuals.... If police intelligence is developed to the point where it factually establishes a criminal offense...
32 CFR 635.5 - Police Intelligence/Criminal Information.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 32 National Defense 4 2013-07-01 2013-07-01 false Police Intelligence/Criminal Information. 635.5... Intelligence/Criminal Information. (a) The purpose of gathering police intelligence is to identify individuals.... If police intelligence is developed to the point where it factually establishes a criminal offense...
Roth, Zvi N
2016-01-01
Neural responses in visual cortex are governed by a topographic mapping from retinal locations to cortical responses. Moreover, at the voxel population level early visual cortex (EVC) activity enables accurate decoding of stimuli locations. However, in many cases information enabling one to discriminate between locations (i.e., discriminative information) may be less relevant than information regarding the relative location of two objects (i.e., relative information). For example, when planning to grab a cup, determining whether the cup is located at the same retinal location as the hand is hardly relevant, whereas the location of the cup relative to the hand is crucial for performing the action. We have previously used multivariate pattern analysis techniques to measure discriminative location information, and found the highest levels in EVC, in line with other studies. Here we show, using representational similarity analysis, that availability of discriminative information in fMRI activation patterns does not entail availability of relative information. Specifically, we find that relative location information can be reliably extracted from activity patterns in posterior intraparietal sulcus (pIPS), but not from EVC, where we find the spatial representation to be warped. We further show that this variability in relative information levels between regions can be explained by a computational model based on an array of receptive fields. Moreover, when the model's receptive fields are extended to include inhibitory surround regions, the model can account for the spatial warping in EVC. These results demonstrate how size and shape properties of receptive fields in human visual cortex contribute to the transformation of discriminative spatial representations into relative spatial representations along the visual stream.
Roth, Zvi N.
2016-01-01
Neural responses in visual cortex are governed by a topographic mapping from retinal locations to cortical responses. Moreover, at the voxel population level early visual cortex (EVC) activity enables accurate decoding of stimuli locations. However, in many cases information enabling one to discriminate between locations (i.e., discriminative information) may be less relevant than information regarding the relative location of two objects (i.e., relative information). For example, when planning to grab a cup, determining whether the cup is located at the same retinal location as the hand is hardly relevant, whereas the location of the cup relative to the hand is crucial for performing the action. We have previously used multivariate pattern analysis techniques to measure discriminative location information, and found the highest levels in EVC, in line with other studies. Here we show, using representational similarity analysis, that availability of discriminative information in fMRI activation patterns does not entail availability of relative information. Specifically, we find that relative location information can be reliably extracted from activity patterns in posterior intraparietal sulcus (pIPS), but not from EVC, where we find the spatial representation to be warped. We further show that this variability in relative information levels between regions can be explained by a computational model based on an array of receptive fields. Moreover, when the model's receptive fields are extended to include inhibitory surround regions, the model can account for the spatial warping in EVC. These results demonstrate how size and shape properties of receptive fields in human visual cortex contribute to the transformation of discriminative spatial representations into relative spatial representations along the visual stream. PMID:27242455
Modified Diet Recipes for Army Medical Facilities
1983-10-20
Mashed 1/2 cup 100 Whole .1-2" diam. 100 Dried Beans 1/2 cup 100 Kidney Corn 1/3 cup 80 Macaroni 1/2 cup 70 Noodles 1/2 cup 80 Peas, green 1/2...5 mg sodium Na/R Bread or Toast Cereal, Cooked Na/R Potato, Sweet Na/R Mashed Na/R Whole Dried Beans Kidney Corn Macaroni Noodles Peas...cup Mashed - no milk 1/3 cup Baked-1/3 of 2-1/4 diam. Diced 1/3 cup Mashed - no milk 1/3 cup Beans, Kidney 1/3 cup Corn Macaroni Noodles
Center for the Evaluation of Biomarkers for the Early Detection of Breast Cancer
2005-10-01
4 servings 1 1/2 pounds boneless, skinless salmon fillet 1/4 cup chopped shallots 2 teaspoons chopped fresh dill 1 tablespoon fresh lemon juice 2...yogurt 1 tablespoon lemon juice To find out more information about women’s cancers, contact: 2 teaspoons minced garlic 1/2 teaspoon salt 1-800...4CANCER 1/4 teaspoon black pepper 1 tablespoon chopped fresh dill www.cancergov.gov-National Cancer Institute 1/4 cup grated, and squeezed dry, English
Hannouf, M B; Winquist, E; Mahmud, S M; Brackstone, M; Sarma, S; Rodrigues, G; Rogan, P; Hoch, J S; Zaric, G S
2017-06-01
We aimed to investigate the cost-effectiveness of a 2000-gene-expression profiling (GEP) test to help identify the primary tumor site when clinicopathological diagnostic evaluation was inconclusive in patients with cancer of unknown primary (CUP). We built a decision-analytic-model to project the lifetime clinical and economic consequences of different clinical management strategies for CUP. The model was parameterized using follow-up data from the Manitoba Cancer Registry, cost data from Manitoba Health administrative databases and secondary sources. The 2000-GEP-based strategy compared to current clinical practice resulted in an incremental cost-effectiveness ratio (ICER) of $44,151 per quality-adjusted life years (QALY) gained. The total annual-budget impact was $36.2 million per year. A value-of-information analysis revealed that the expected value of perfect information about the test's clinical impact was $4.2 million per year. The 2000-GEP test should be considered for adoption in CUP. Field evaluations of the test are associated with a large societal benefit.
Spoon-to-Cup Fading as Treatment for Cup Drinking in a Child with Intestinal Failure
ERIC Educational Resources Information Center
Groff, Rebecca A.; Piazza, Cathleen C.; Zeleny, Jason R.; Dempsey, Jack R.
2011-01-01
We treated a child with intestinal failure who consumed solids on a spoon but not liquids from a cup. We used spoon-to-cup fading, which consisted of taping a spoon to a cup and then gradually moving the bowl of the spoon closer to the edge of the cup. Spoon-to-cup fading was effective for increasing consumption of liquids from a cup. (Contains 2…
Educational Programs for Intelligence Professionals.
ERIC Educational Resources Information Center
Miller, Jerry P.
1994-01-01
Discusses the need for education programs for competitive intelligence professionals. Highlights include definitions of intelligence functions, focusing on business intelligence; information utilization by decision makers; information sources; competencies for intelligence professionals; and the development of formal education programs. (38…
Developing Information Systems for Competitive Intelligence Support.
ERIC Educational Resources Information Center
Hohhof, Bonnie
1994-01-01
Discusses issues connected with developing information systems for competitive intelligence support; defines the elements of an effective competitive information system; and summarizes issues affecting system design and implementation. Highlights include intelligence information; information needs; information sources; decision making; and…
Experimental Investigation of the Robinson-Type Cup Anemometer
NASA Technical Reports Server (NTRS)
Brevoort, M J; Joyner, U T
1936-01-01
This report presents the results of wind tunnel tests on a Robinson-type anemometer. The investigation covered force measurements on individual cups, as well as static and dynamic torque measurements and calibrations on complete cup wheels. In the tests on individual cups 5 cup forms were used and in the measurements on complete cup wheels 4 cup wheels with 3 arm lengths for each cup wheel were tested. All the results are presented in graphical form.
Liang, Jinyang; Gao, Liang; Hai, Pengfei; Li, Chiye; Wang, Lihong V.
2015-01-01
Compressed ultrafast photography (CUP), a computational imaging technique, is synchronized with short-pulsed laser illumination to enable dynamic three-dimensional (3D) imaging. By leveraging the time-of-flight (ToF) information of pulsed light backscattered by the object, ToF-CUP can reconstruct a volumetric image from a single camera snapshot. In addition, the approach unites the encryption of depth data with the compressed acquisition of 3D data in a single snapshot measurement, thereby allowing efficient and secure data storage and transmission. We demonstrated high-speed 3D videography of moving objects at up to 75 volumes per second. The ToF-CUP camera was applied to track the 3D position of a live comet goldfish. We have also imaged a moving object obscured by a scattering medium. PMID:26503834
NASA Technical Reports Server (NTRS)
Topol, David A.
1999-01-01
TFaNS is the Tone Fan Noise Design/Prediction System developed by Pratt & Whitney under contract to NASA Lewis (presently NASA Glenn). The purpose of this system is to predict tone noise emanating from a fan stage including the effects of reflection and transmission by the rotor and stator and by the duct inlet and nozzle. These effects have been added to an existing annular duct/isolated stator noise prediction capability. TFaNS consists of: The codes that compute the acoustic properties (reflection and transmission coefficients) of the various elements and write them to files. Cup3D: Fan Noise Coupling Code that reads these files, solves the coupling problem, and outputs the desired noise predictions. AWAKEN: CFD/Measured Wake Postprocessor which reformats CFD wake predictions and/or measured wake data so it can be used by the system. This volume of the report provides technical background for TFaNS including the organization of the system and CUP3D technical documentation. This document also provides information for code developers who must write Acoustic Property Files in the CUP3D format. This report is divided into three volumes: Volume I: System Description, CUP3D Technical Documentation, and Manual for Code Developers; Volume II: User's Manual, TFaNS Vers. 1.4; Volume III: Evaluation of System Codes.
Mohaddes, Maziar; Rolfson, Ola; Kärrholm, Johan
2015-02-01
The use of trabecular metal (TM) cups in revision surgery has increased worldwide during the last decade. Since the introduction of the TM cup in Sweden in 2006, this design has gradually replaced other uncemented designs used in Sweden. According to data from the Swedish Hip Arthroplasty Register (SHAR) in 2012, one-third of all uncemented first-time cup revisions were performed using a TM cup. We compared the risk of reoperation and re-revision for TM cups and the 2 other most frequently used cup designs in acetabular revisions reported to the SHAR. The hypothesis was that the performance of TM cups is as good as that of established designs in the short term. The study population consisted of 2,384 patients who underwent 2,460 revisions during the period 2006 through 2012. The most commonly used cup designs were the press-fit porous-coated cup (n = 870), the trabecular metal cup (n = 805), and the cemented all-polyethylene cup (n = 785). 54% of the patients were female, and the median age at index revision was 72 (19-95) years. Reoperation was defined as a second surgical intervention, and re-revision-meaning exchange or removal of the cup-was used as endpoint. The mean follow-up time was 3.3 (0-7) years. There were 215 reoperations, 132 of which were re-revisions. The unadjusted and adjusted risk of reoperation or re-revision was not significantly different for the TM cup and the other 2 cup designs. Our data support continued use of TM cups in acetabular revisions. Further follow-up is necessary to determine whether trabecular metal cups can reduce the re-revision rate in the long term, compared to the less costly porous press-fit and cemented designs.
Kaku, Nobuhiro; Tabata, Tomonori; Tsumura, Hiroshi
2015-12-01
We verified the index cup position required for bulk bone grafting instead of morcellized grafting immediately after cementless total hip arthroplasty. Three-dimensional finite element analysis was used to evaluate changes in the volume of the slippage of the cup-host bone interface as micro-motion of the cup at the acetabular bone defect site depending on the cup-center-edge (CE) angle. The conditions of bulk bone grafts were similar to those of cortical bone. Slippage increased with decreasing cup-CE angle. A bulk bone graft tightly fixed to the host bone prevented considerably larger slippage between the cup and host bone. A smaller cup-CE angle increased the impact of the bulk bone graft on slippage. When the cup-CE angle was 0° or -10°, the criterion for slippage in favorable initial fixation in all conditions was <40 μm. Even if transplanted bulk bone is used, unless good fixation is obtained between the host bone, and the cup and bone graft, it is impossible to obtain reliable fixation of the cup with a cup-CE angle <-10° and slippage exceeding 40 μm. Bulk bone grafting tightly fixed to the host bone improves initial the cup-host bone fixation, especially when the cup-CE angle is small, such as <-10°. In clinical practice, negative factors are implicated in the initial fixation of various cups, and sufficient fixation between the host bone and cup or bulk bone graft using a screw is effective when the cup-CE angle is extremely small.
Federal Register 2010, 2011, 2012, 2013, 2014
2010-08-16
... DEPARTMENT OF JUSTICE [OMB Number 1105-0087] National Drug Intelligence Center: Agency Information...), National Drug Intelligence Center (NDIC), will be submitting the following information collection request... Kevin M. Walker, General Counsel, National Drug Intelligence Center, Fifth Floor, 319 Washington Street...
The Intelligent Technologies of Electronic Information System
NASA Astrophysics Data System (ADS)
Li, Xianyu
2017-08-01
Based upon the synopsis of system intelligence and information services, this paper puts forward the attributes and the logic structure of information service, sets forth intelligent technology framework of electronic information system, and presents a series of measures, such as optimizing business information flow, advancing data decision capability, improving information fusion precision, strengthening deep learning application and enhancing prognostic and health management, and demonstrates system operation effectiveness. This will benefit the enhancement of system intelligence.
Acoustic Performance of 3D Printed Nanocomposite Earmuff
Ahmadi, Saeid; Nassiri, Parvin; Ghasemi, Ismaeil; Monazzam Ep, Mohammad R.
2016-01-01
Introduction: Hearing protection devices are one of the primary noise reduction tools in developing countries. This study is intended to produce and apply acrylonitrile butadiene styrene (ABS)/clay nanocomposites to fabricate a laboratory single cup earmuffs and then compare it with double cup and single cup pure ABS earmuffs in terms of noise attenuation performance and comfort. In addition, the noise attenuation performance of single cup pure ABS earmuffs is compared with double cup pure ABS earmuffs. Methods: ABS/nanoclay filament was fabricated using a twin screw extruder. A three dimensional (3D) printing machine and a 3D model of earcup, designed by solid work software, were applied to print single and double cup earmuffs using ABS/nanoclay composite and pure ABS filaments. Finally, using an acoustic test fixture, objective noise attenuation test was performed on three different types of earmuffs, including with and without nano material and a secondary cup. Moreover, earmuffs weight was measured as a comfort component. Results: Insertion loss and calculated noise reduction rating (NRR) of single cup ABS/nanoclay earmuffs (NRR=19.4 dB) and double cup pure ABS earmuffs (NRR=18.93 dB) were improved in comparison with single cup pure ABS earmuffs (NRR=15.7 dB). Additionally, both single cup earmuffs were significantly lighter than double cup earmuffs. Although single cup nano and double cup earmuffs had nearly the same attenuation performance, single cup nano earmuffs were 74 gr lighter than double cup earmuffs, so with reference to comfort, single cup nano earmuffs will probably be more acceptable. Conclusions: From this survey it might be concluded that, even though single cup ABS/nanoclay earmuffs was lighter than double cup pure ABS earmuffs, it had approximately more attenuation performance in comparison with double cup pure ABS earmuffs. Consequently, users are probably more prone to wear light- weight single cup ABS/nanoclay earmuffs as a result of improved comfort. In short, ABS/nanoclay composite can be considered a good choice in products with the necessity of high acoustic performance and low weight. PMID:26234977
Goodman, Alyson B; Blanck, Heidi M; Sherry, Bettylou; Park, Sohyun; Nebeling, Linda; Yaroch, Amy L
2013-04-11
Water is vital for life, and plain water is a calorie-free option for hydration. Increasing consumption of drinking water is a strategy to reduce energy intake and lose or maintain weight; however, information on the characteristics of consumers who drink water is limited. Our objective was to describe the characteristics of people who have a low intake of drinking water and to determine associations between their behaviors and attitudes and their intake of water. We analyzed data from a nationally representative sample of 3,397 US adults who participated in the National Cancer Institute's 2007 Food Attitudes and Behaviors Survey. Multivariable logistic regression was used to identify sociodemographic characteristics and health-related behaviors and attitudes associated with self-reported drinking water intake of less than 4 cups per day. Overall, 7% of adults reported no daily consumption of drinking water, 36% reported drinking 1 to 3 cups, 35% reported drinking 4 to 7 cups, and 22% reported drinking 8 cups or more. The likelihood of drinking less than 4 cups of water daily was significantly higher among participants aged 55 years or older than among those aged 18 to 34 (adjusted odds ratio [AOR], 1.3), among residents of the Northeast than among residents of the South (AOR, 1.4), among participants who consumed 1 cup or less of fruits or vegetables per day than among those who consumed 4.5 cups or more (AOR, 3.0), among participants who did not exercise than among those who exercised 150 minutes or more per week (AOR, 1.7), and among participants who were neither trying to gain nor lose weight than among those trying to lose weight (AOR, 1.3). Low drinking water intake was associated with age, region of residence, and several unhealthful behaviors and attitudes. Understanding characteristics associated with low drinking water intake may help to identify populations that could benefit from interventions to help adults drink more water.
Co-ordination of NDH and Cup proteins in CO2 uptake in cyanobacterium Synechocystis sp. PCC 6803.
Han, Xunling; Sun, Nan; Xu, Min; Mi, Hualing
2017-06-01
High and low affinity CO2-uptake systems containing CupA (NDH-1MS) and CupB (NDH-1MS'), respectively, have been identified in Synechocystis sp. PCC 6803, but it is yet unknown how the complexes function in CO2 uptake. In this work, we found that deletion of cupB significantly lowered the growth of cells, and deletion of both cupA and cupB seriously suppressed the growth below pH 7.0 even under 3% CO2. The rate of photosynthetic oxygen evolution was decreased slightly by deletion of cupA but significantly by deletion of cupB and more severely by deletion of both cupA and cupB, especially in response to changed pH conditions under 3% CO2. Furthermore, we found that assembly of CupB into NDH-1MS' was dependent on NdhD4 and NdhF4. NDH-1MS' was not affected in the NDH-1MS-degradation mutant and NDH-1MS was not affected in the NDH-1MS'-degradation mutants, indicating the existence of independent CO2-uptake systems under high CO2 conditions. The light-induced proton gradient across thylakoid membranes was significantly inhibited in ndhD-deletion mutants, suggesting that NdhDs functions in proton pumping. The carbonic anhydrase activity was suppressed partly in the cupA- or cupB-deletion mutant but severely in the mutant with both cupA and cupB deletion, indicating that CupA and CupB function in conversion of CO2 to HCO3-. In turn, deletion of cup genes lowered the transthylakoid membrane proton gradient and deletion of ndhDs decreased the CO2 hydration. Our results suggest that NDH-1M provides an alkaline region to activate Cup proteins involved in CO2 uptake. © The Author 2017. Published by Oxford University Press on behalf of the Society for Experimental Biology.
77 FR 2659 - Airworthiness Directives; Cessna Aircraft Company Airplanes
Federal Register 2010, 2011, 2012, 2013, 2014
2012-01-19
...), and of the bearing cup for corrosion, turned cup, or clearance that exceeds limits, and repair as... cup for corrosion, turned cup, or clearance that exceeds limits, and repair if necessary; measuring... on the metal), and of the bearing cup for corrosion, turned cup, or clearance that exceeds limits...
Cup tool use by squirrel monkeys.
Buckmaster, Christine L; Hyde, Shellie A; Parker, Karen J; Lyons, David M
2015-12-01
Captive-born male and female squirrel monkeys spontaneously 'invented' a cup tool use technique to Contain (i.e., hold and control) food they reduced into fragments for consumption and to Contain water collected from a valve to drink. Food cup use was observed more frequently than water cup use. Observations indicate that 68% (n = 39/57) of monkeys in this population used a cup (a plastic slip cap) to Contain food, and a subset of these monkeys, 10% (n = 4/39), also used a cup to Contain water. Cup use was optional and did not replace, but supplemented, the hand/arm-to-mouth eating and direct valve drinking exhibited by all members of the population. Strategies monkeys used to bring food and cups together for food processing activity at preferred upper-level perching areas, in the arboreal-like environment in which they lived, provides evidence that monkeys may plan food processing activity with the cups. Specifically, prior to cup use monkeys obtained a cup first before food, or obtained food and a cup from the floor simultaneously, before transporting both items to upper-level perching areas. After food processing activity with cups monkeys rarely dropped the cups and more often placed the cups onto perching. Monkeys subsequently returned to use cups that they previously placed on perching after food processing activity. The latter behavior is consistent with the possibility that monkeys may keep cups at preferred perching sites for future food processing activity and merits experimental investigation. Reports of spontaneous tool use by squirrel monkeys are rare and this is the first report of population-level tool use. These findings offer insights into the cognitive abilities of squirrel monkeys and provide a new context for behavior studies with this genus and for comparative studies with other primates. © 2015 Wiley Periodicals, Inc.
78 FR 53172 - Agency Information Collection Activities
Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-28
... OFFICE OF THE DIRECTOR OF NATIONAL INTELLIGENCE Agency Information Collection Activities AGENCY: Office of the Director of National Intelligence (ODNI). ACTION: Notice. SUMMARY: The Whistleblower... Information Officer, Information Management Division, Office of the Director of National Intelligence...
Competitive Intelligence and the Information Center.
ERIC Educational Resources Information Center
Greene, H. Frances
1988-01-01
Examines the competitive intelligence approach to corporate information gathering, and discusses how it differs from the traditional library information center approach. Steps for developing a competitive intelligence system in the library information center are suggested. (33 references) (MES)
Wet cupping therapy restores sympathovagal imbalances in cardiac rhythm.
Arslan, Müzeyyen; Yeşilçam, Nesibe; Aydin, Duygu; Yüksel, Ramazan; Dane, Senol
2014-04-01
A recent study showed that cupping had therapeutic effects in rats with myocardial infarction and cardiac arrhythmias. The current studyaimed to investigate the possible useful effects of cupping therapy on cardiac rhythm in terms of heart rate variability (HRV). Forty healthy participants were included. Classic wet cupping therapy was applied on five points of the back. Recording electrocardiography (to determine HRV) was applied 1 hour before and 1 hour after cupping therapy. All HRV parameters increased after cupping therapy compared with before cupping therapy in healthy persons. These results indicate for the first time in humans that cupping might be cardioprotective. In this study, cupping therapy restored sympathovagal imbalances by stimulating the peripheral nervous system.
Evaluation of Wet Cupping Therapy: Systematic Review of Randomized Clinical Trials.
Al Bedah, Abdullah M N; Khalil, Mohamed K M; Posadzki, Paul; Sohaibani, Imen; Aboushanab, Tamer Shaaban; AlQaed, Meshari; Ali, Gazzaffi I M
2016-10-01
Wet cupping is a widely used traditional therapy in many countries, which justifies a continuous scientific evaluation of its efficacy and safety. To perform a systematic review to critically evaluate and update the available evidence of wet cupping in traditional and complementary medicine. Ten electronic databases were searched from their inceptions to February 2016. Included studies were randomized clinical trials (RCTs) that evaluated wet cupping against any type of control interventions in patients with any clinical condition, as well as healthy individuals. Cochrane risk of bias tool was used to appraise the included RCTs. Fourteen RCTs met the eligibility criteria. The included studies evaluated the following clinical conditions: nonspecific low back pain (NSLBP), hypertension, brachialgia, carpal tunnel syndrome (CTS), chronic neck pain, metabolic syndrome, migraine headaches, oxygen saturation in smokers with chronic obstructive pulmonary disease (COPD), and oral and genital ulcers due to Behçet disease. Two RCTs evaluated physiologic and biochemical parameters of healthy individuals. Overall, 9 RCTs favored wet cupping over various control interventions in NSLBP (n = 2), hypertension (n = 1), brachialgia (n = 1), CTS (n = 1), chronic neck pain (n = 2), oxygen saturation in smokers with COPD (n = 1), and oral and genital ulcers due to Behçet disease (n = 1). Five RCTs showed no statistically significant between-group differences: NSLBP (n = 1), metabolic syndrome (n = 1), migraine headaches (n = 1), and physiologic and biochemical parameters of healthy individuals (n = 2). Included RCTs had a variable risk of bias across all domains and suffered methodologic limitations. There is a promising evidence in favor of the use of wet cupping for musculoskeletal pain, specifically NSLBP, neck pain, CTS, and brachialgia. Better-quality trials are needed to generate solid evidence and firmly inform policy makers.
Yaghjyan, Lusine; Rich, Shannan; Mao, Liang; Mai, Volker; Egan, Kathleen M
2018-06-01
We investigated the association of coffee consumption with postmenopausal breast cancer risk, overall and by the status of postmenopausal hormone therapy (PMH). This study included 126,182 postmenopausal women (2,636 with breast cancer and 123,546 without) from UK Biobank. Cancer diagnoses were ascertained through the linkage to the UK National Health Service Central Registers. Information on breast cancer risk factors and coffee consumption was collected at baseline and updated during follow-up. We used Cox proportional hazards regression to evaluate associations between coffee consumption and breast cancer, overall and in stratified analyses by woman's PMH status (none, past, current). In the overall analysis, coffee consumption was not associated with breast cancer risk (Hazard Ratio [HR] 1.00, 95% CI 0.91-1.11 for 2-3 cups/day, and HR 0.98, 95% CI 0.87-1.10 for ≥ 4 cups/day, p-trend = 0.69). Women with no PMH history who consumed ≥ 4 cups/day had a 16% reduced risk of breast cancer as compared to women who consumed < 7 cups/week (HR 0.84, 95% CI 0.71-1.00). Among women with past PMH, those consuming ≥ 4 cups/day had a 22% greater risk of breast cancer than women consuming < 7 cups/week (HR 1.22, 95% CI 1.01-1.47). No association was found among current PMH users. We found no significant interaction between PMH and coffee consumption (p = 0.24). Coffee consumption might be associated with increased breast cancer risk in women who used hormones in the past. Further studies are warranted to confirm these findings and elucidate potential biological mechanisms underlying the observed associations.
Joint optic disc and cup boundary extraction from monocular fundus images.
Chakravarty, Arunava; Sivaswamy, Jayanthi
2017-08-01
Accurate segmentation of optic disc and cup from monocular color fundus images plays a significant role in the screening and diagnosis of glaucoma. Though optic cup is characterized by the drop in depth from the disc boundary, most existing methods segment the two structures separately and rely only on color and vessel kink based cues due to the lack of explicit depth information in color fundus images. We propose a novel boundary-based Conditional Random Field formulation that extracts both the optic disc and cup boundaries in a single optimization step. In addition to the color gradients, the proposed method explicitly models the depth which is estimated from the fundus image itself using a coupled, sparse dictionary trained on a set of image-depth map (derived from Optical Coherence Tomography) pairs. The estimated depth achieved a correlation coefficient of 0.80 with respect to the ground truth. The proposed segmentation method outperformed several state-of-the-art methods on five public datasets. The average dice coefficient was in the range of 0.87-0.97 for disc segmentation across three datasets and 0.83 for cup segmentation on the DRISHTI-GS1 test set. The method achieved a good glaucoma classification performance with an average AUC of 0.85 for five fold cross-validation on RIM-ONE v2. We propose a method to jointly segment the optic disc and cup boundaries by modeling the drop in depth between the two structures. Since our method requires a single fundus image per eye during testing it can be employed in the large-scale screening of glaucoma where expensive 3D imaging is unavailable. Copyright © 2017 Elsevier B.V. All rights reserved.
Coffee, tea, caffeine, and risk of hypertension: The Singapore Chinese Health Study.
Chei, Choy-Lye; Loh, Julian Kenrick; Soh, Avril; Yuan, Jian-Min; Koh, Woon-Puay
2018-06-01
The relationship between coffee and tea, and risk of hypertension remains controversial in Western populations. We investigated these associations in an Asian population. The Singapore Chinese Health Study is a population-based prospective cohort that recruited 63,257 Chinese aged 45-74 years and residing in Singapore from 1993 to 1998. Information on consumption of coffee, tea, and other lifestyle factors was collected at baseline, and self-reported physician-diagnosed hypertension was assessed during two follow-up interviews (1999-2004, 2006-2010). We identified 13,658 cases of incident hypertension after average 9.5 years. Compared to those who drank one cup of coffee/day, the hazard ratios (HR) and 95% confidence intervals (CI) were 0.87 (0.83-0.91) for
Influence of height, weight, and body mass index on optic disc parameters.
Zheng, Yingfeng; Cheung, Carol Y L; Wong, Tien Y; Mitchell, Paul; Aung, Tin
2010-06-01
To examine the influence of body height, body weight, and body mass index (BMI) on optic disc parameters in a population-based study. The Singapore Malay Eye Study examined 3280 persons of Malay ethnicity, aged 40 to 80 years, of whom 2329 (71.0%) had reliable retinal scanning confocal laser tomography images for analyses. Intraocular pressure (IOP) was ascertained by Goldmann applanation tonometry. Body height and weight were measured with standardized protocols; BMI was calculated as weight (kilograms)/height squared (meters). Sociodemographic information was collected in an interviewer-administered questionnaire. In univariate analyses, body height, weight, and BMI were significantly associated with optic cup area, rim area, and cup-to-disc area ratio (all with P < 0.05) but none of the anthropometric parameters was significantly associated with optic disc area (all with P > 0.05). In multiple regression analyses after adjustment for age, sex, optic disc size, axial length, education, family income, and IOP, each SD increase in body height was associated with a 0.042-mm(2) decrease in optic rim area and a 0.020 increase in optic cup-to-disc area ratio; each SD decrease in body weight was associated with a 0.013-mm(2) decrease in optic rim area and a 0.010 increase in optic cup-to-disc ratio; and each SD decrease in BMI was associated with a 0.021-mm(2) decrease in optic rim area and a 0.010 increase in optic cup-to-disc ratio. Persons who are taller or have lower BMI have a smaller neuroretinal rim area and a larger optic cup-to-disc area ratio.
Fixation strength analysis of cup to bone material using finite element simulation
NASA Astrophysics Data System (ADS)
Anwar, Iwan Budiwan; Saputra, Eko; Ismail, Rifky; Jamari, J.; van der Heide, Emile
2016-04-01
Fixation of acetabular cup to bone material is an important initial stability for artificial hip joint. In general, the fixation in cement less-type acetabular cup uses press-fit and screw methods. These methods can be applied alone or together. Based on literature survey, the additional screw inside of cup is effective; however, it has little effect in whole fixation. Therefore, an acetabular cup with good fixation, easy manufacture and easy installation is required. This paper is aiming at evaluating and proposing a new cup fixation design. To prove the strength of the present cup fixation design, the finite element simulation of three dimensional cup with new fixation design was performed. The present cup design was examined with twist axial and radial rotation. Results showed that the proposed cup design was better than the general version.
Ellenrieder, Martin; Bader, Rainer; Bergschmidt, Philipp; Mittelmeier, Wolfram
2016-03-01
Prospectively the outcome after total hip replacement with a new threaded acetabular cup design was compared to an established press-fit cup. After 1, 2 and 5 years, the 36-item Short Form Health Survey, Western Ontario and McMaster University Osteoarthritis Index and Harris Hip Score revealed no significant differences between the two groups (each group: n=42 patients), except for a higher Harris Hip Score in the threaded cup group after five years (p=0.02). After five years, one threaded cup had a mild radiolucent line without further signs of loosening. All other cups of both groups (98.6%) showed a full osseous integration. The cup inclination angle ranged from 41-58° (threaded cups) to 39-77° (press-fit cups). The new threaded cup provides equivalent clinical outcomes and osseous integration but more precise implant positioning compared to the press-fit design. No complications typically ascribed to threaded cups (acetabular fractures, bone resorption, nerve impairment) occurred.
[Progress of researches on the mechanism of cupping therapy].
Cui, Shuai; Cui, Jin
2012-12-01
Cupping therapy of Chinese medicine is able to relieve a variety of diseases or clinical conditions, which results from the comprehensive effects of multiple types of stimulation exerted onto the regional acupoint areas. Among the stimuli, the negative pressure from cupping is one of the main factors inducing therapeutic effects. In the present paper, the authors review development of researches on the underlying mechanism of therapeutic effects of cupping-negative pressure from 1) the factor of intra-cup negative pressure; 2) influence of intra-cup negative pressure on cup-blackspot formation; 3) influence of cupping on regional blood vessels and blood flow; 4) effect of cupping on regional ultrastructure of the capillary in the raw-surface tissue; 5) effect of cupping-negative pressure on regional endothelial cells; and 6) biological effects of negative pressure drainage. Generally, cupping induced negative pressure can dilate local blood vessels to improve microcirculation, promote capillary endothelial cells repair, accelerate granulation and angiogenesis, etc., in the regional tissues, normalizing the patients' functional state at last.
Hanson, John P.; Sabolcik, Rudolph E.; Svedberg, Robert C.
1976-11-16
In a multifoil thermal insulation package having a plurality of concentric cylindrical cups, means are provided for reducing heat loss from the penetration region which extends through the cups. At least one cup includes an integral skirt extending from one end of the cup to intersection with the penetration means. Assembly of the insulation package with the skirted cup is facilitated by splitting the cup to allow it to be opened up and fitted around the other cups during assembly.
An updated review of the efficacy of cupping therapy.
Cao, Huijuan; Li, Xun; Liu, Jianping
2012-01-01
Since 1950, traditional Chinese medicine (TCM) cupping therapy has been applied as a formal modality in hospitals throughout China and elsewhere in the world. Based on a previous systematic literature review of clinical studies on cupping therapy, this study presents a thorough review of randomized controlled trials (RCTs) to evaluate the therapeutic effect of cupping therapy. Six databases were searched for articles published through 2010. RCTs on cupping therapy for various diseases were included. Studies on cupping therapy combined with other TCM treatments versus non-TCM therapies were excluded. 135 RCTs published from 1992 through 2010 were identified. The studies were generally of low methodological quality. Diseases for which cupping therapy was commonly applied were herpes zoster, facial paralysis (Bell palsy), cough and dyspnea, acne, lumbar disc herniation, and cervical spondylosis. Wet cupping was used in most trials, followed by retained cupping, moving cupping, and flash cupping. Meta-analysis showed cupping therapy combined with other TCM treatments was significantly superior to other treatments alone in increasing the number of cured patients with herpes zoster, facial paralysis, acne, and cervical spondylosis. No serious adverse effects were reported in the trials. Numerous RCTs on cupping therapy have been conducted and published during the past decades. This review showed that cupping has potential effect in the treatment of herpes zoster and other specific conditions. However, further rigorously designed trials on its use for other conditions are warranted.
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...] Special Local Regulation and Safety Zone; America's Cup Sailing Events, San Francisco, CA AGENCY: Coast... ``Louis Vuitton Cup, Red Bull Youth America's Cup and the 34th America's Cup'' regatta scheduled from July... associated with the 34th America's Cup sailing events taking place adjacent to the City of San Francisco...
[Impacts on skin blood flow under moving cupping along meridians in different directions].
Tian, Yu-Ying; Wang, Guang-Jun; Huang, Tao; Jia, Shu-Yong; Zhang, Yu-Qin; Zhang, Wei-Bo
2013-03-01
To compare the impacts on skin blood flow between moving cupping following the meridian running direction and that against the running direction. JLG-2 meridian cupping drainage instru ment was used for moving cupping on the back along the Bladder Meridian running course in either single direction for 20 times. The cupping device was Bian stone cup, 44 mm in inner diameter, negative pressure from -0.03 to -0.04 MPa. PeriScan PIM II laser Doppler perfusion imager was used to observe the changes in skin blood flow on the running course of the Bladder Meridian with cup moved up and down and in the same region on the contralateral Bladder Meridian. Blood flow was measured before cupping, at the immediate time after cupping and 10 min after cupping separately. Fourteen healthy volunteers received the test. The measuring region was subdivided into a moving cupping area, an upstream area, a downstream area, a contralateral moving cupping area, a contralateral upstream area and a contralateral downstream area. The mean blood flow was calculated in each area. Blood flow was increased significantly in each area and was more apparently increased in the moving cupping area. In comparison of the changing rate of blood flow between cupping following the meridian running direction and that against the running direction, it was only found that the changing rate in the upstream area of moving cupping against the running direction was significantly higher than that following the running direction (P < 0.05). The differences were not statistically significant in comparison among the other areas. Additionally, the changing rates of blood flow in the upstream and downstream area of the Bladder Meridian were increased significantly as compared with the contralateral Bladder Meridian. The local effects are similar between moving cupping following the meridian running direction and that against the running direction. The abscopal effect of moving cupping against the running direction is superior to that following the running direction. It is suggested that the dual-directional moving cupping is applicable for the treatment of local disorders and the abscopal effect is better with moving cupping against the meridian running direction.
Intelligence, Information Technology, and Information Warfare.
ERIC Educational Resources Information Center
Davies, Philip H. J.
2002-01-01
Addresses the use of information technology for intelligence and information warfare in the context of national security and reviews the status of clandestine collection. Discusses hacking, human agent collection, signal interception, covert action, counterintelligence and security, and communications between intelligence producers and consumers…
Acquiring neural signals for developing a perception and cognition model
NASA Astrophysics Data System (ADS)
Li, Wei; Li, Yunyi; Chen, Genshe; Shen, Dan; Blasch, Erik; Pham, Khanh; Lynch, Robert
2012-06-01
The understanding of how humans process information, determine salience, and combine seemingly unrelated information is essential to automated processing of large amounts of information that is partially relevant, or of unknown relevance. Recent neurological science research in human perception, and in information science regarding contextbased modeling, provides us with a theoretical basis for using a bottom-up approach for automating the management of large amounts of information in ways directly useful for human operators. However, integration of human intelligence into a game theoretic framework for dynamic and adaptive decision support needs a perception and cognition model. For the purpose of cognitive modeling, we present a brain-computer-interface (BCI) based humanoid robot system to acquire brainwaves during human mental activities of imagining a humanoid robot-walking behavior. We use the neural signals to investigate relationships between complex humanoid robot behaviors and human mental activities for developing the perception and cognition model. The BCI system consists of a data acquisition unit with an electroencephalograph (EEG), a humanoid robot, and a charge couple CCD camera. An EEG electrode cup acquires brainwaves from the skin surface on scalp. The humanoid robot has 20 degrees of freedom (DOFs); 12 DOFs located on hips, knees, and ankles for humanoid robot walking, 6 DOFs on shoulders and arms for arms motion, and 2 DOFs for head yaw and pitch motion. The CCD camera takes video clips of the human subject's hand postures to identify mental activities that are correlated to the robot-walking behaviors. We use the neural signals to investigate relationships between complex humanoid robot behaviors and human mental activities for developing the perception and cognition model.
Compression in Working Memory and Its Relationship With Fluid Intelligence.
Chekaf, Mustapha; Gauvrit, Nicolas; Guida, Alessandro; Mathy, Fabien
2018-06-01
Working memory has been shown to be strongly related to fluid intelligence; however, our goal is to shed further light on the process of information compression in working memory as a determining factor of fluid intelligence. Our main hypothesis was that compression in working memory is an excellent indicator for studying the relationship between working-memory capacity and fluid intelligence because both depend on the optimization of storage capacity. Compressibility of memoranda was estimated using an algorithmic complexity metric. The results showed that compressibility can be used to predict working-memory performance and that fluid intelligence is well predicted by the ability to compress information. We conclude that the ability to compress information in working memory is the reason why both manipulation and retention of information are linked to intelligence. This result offers a new concept of intelligence based on the idea that compression and intelligence are equivalent problems. Copyright © 2018 Cognitive Science Society, Inc.
Novel cemented cup-holding technique while performing total hip arthroplasty with navigation system.
Takai, Hirokazu; Takahashi, Tomoki
2017-09-01
Recently, navigation systems have been more widely utilized in total hip arthroplasty. However, almost all of these systems have been developed for cementless cups. In the case of cemented total hip arthroplasty using a navigation system, a special-ordered cemented holder is needed. We propose a novel cemented cup-holding technique for navigation systems using readily available articles. We combine a cementless cup holder with an inverted cementless trial cup. The resulting apparatus is used as a cemented cup holder. The upside-down cup-holding technique is useful and permits cemented cup users to utilize a navigation system for placement of the acetabular component.
Kim, Young-Ho
2017-09-01
The use of acetabular cup revision arthroplasty is on the rise as demands for total hip arthroplasty, improved life expectancies, and the need for individual activity increase. For an acetabular cup revision to be successful, the cup should gain stable fixation within the remaining supportive bone of the acetabulum. Since the patient's remaining supportive acetabular bone stock plays an important role in the success of revision, accurate classification of the degree of acetabular bone defect is necessary. The Paprosky classification system is most commonly used when determining the location and degree of acetabular bone loss. Common treatment options include: acetabular liner exchange, high hip center, oblong cup, trabecular metal cup with augment, bipolar cup, bulk structural graft, cemented cup, uncemented cup including jumbo cup, acetabular reinforcement device (cage), trabecular metal cup cage. The optimal treatment option is dependent upon the degree of the discontinuity, the amount of available bone stock and the likelihood of achieving stable fixation upon supportive host bone. To achieve successful acetabular cup revision, accurate evaluation of bone defect preoperatively and intraoperatively, proper choice of method of acetabular revision according to the evaluation of acetabular bone deficiency, proper technique to get primary stability of implant such as precise grafting technique, and stable fixation of implant are mandatory.
Equy, Véronique; David-Tchouda, Sandra; Dreyfus, Michel; Riethmuller, Didier; Vendittelli, Françoise; Cabaud, Victoire; Langer, Bruno; Margier, Jennifer; Bosson, Jean-Luc; Schaal, Jean-Patrick
2015-12-15
Assisted vaginal delivery by vacuum extraction is frequent. Metallic resterilizible metallic vacuum cups have been routinely used in France. In the last few years a new disposable semi-soft vacuum extraction cup, the iCup, has been introduced. Our objective was to compare maternal and new-born outcomes between this disposable cup and the commonly used Drapier-Faure metallic cup. This was a multicenter prospective randomized controlled open clinical trial performed in the maternity units of five university hospitals and one community hospital in France from October 2009 to February 2013. We included consecutive eligible women with a singleton gestation of at least 37 weeks who required vacuum assisted delivery. Women were randomized to vacuum extraction using the iCup or usual Drapier-Faure metallic cup. The primary outcome was a composite criterion including both the risk of cup dysfunction and the most frequent maternal and neonatal harms: the use of other instruments after attempted vacuum extraction, caesarean section after attempted vacuum extraction, three detachments of the cup, caput succedaneum, cephalohaematoma, episiotomy and perineal tears. 335 women were randomized to the disposable cup and 333 to extraction using the metallic cup. There was no significant difference between the two groups for the primary outcome. However, failed instrumental delivery was more frequent in the disposable cup group, mainly due to detachment: 35.6 % vs 7.1 %, p < 0.0001. Conversely, perineal tears were more frequent in the metallic cup group, especially third or fourth grade perineal tears: 1.7 % versus 5.0 %, p = 0.003. There were no significant differences between the two groups concerning post-partum haemorrhage, transfer to a neonatal intensive care unit (NICU) or serious adverse events. While the disposable cup had more detachments and extraction failures than the standard metallic cup, this innovative disposable device had the advantage of fewer perineal injuries. www.clinicaltrials.gov : NCT01058200 on Jan. 27 2010.
Important considerations about nursing intelligence and information systems.
Ballard, E C
1997-01-01
This discussion focuses on the importance of nursing intelligence to the organisation, and the nurses' role in gathering and utilising such intelligence. Deliberations with professional colleagues suggest that intelligence can only be utilised fully when the information systems are developed in such a way as to meet the needs of the people who manage and provide nursing care at the consumer level; that is, the activity of nursing itself. If accommodation is made for the recycling of nursing intelligence, there would be a support and furtherance of 'professional' intelligence. Two main issues emerge: how can nurses support the needs of management to optimise intelligence input? how can organisations optimise the contribution of nurses to its information processes and interpretation of intelligence? The expansion of this 'professional' intelligence would promote a generation of constantly reviewed data, offering a quality approach to nursing activities and an organisation's intelligence system.
Shawaf, Turke; El-Deeb, Wael; Hussen, Jamal; Hendi, Mahmoud; Al-Bulushi, Shahab
2018-01-01
Aim: Recently, the complementary therapies such as cupping and acupuncture are being used in veterinary medicine. This research was carried out to determine the effects of wet cupping therapy (Hijama) on the hematological and the biochemical parameters in the healthy Arabian horses for the first time. Materials and Methods: In this study, seven clinically healthy Arabian horses were randomly selected. Four points on the animal body were selected to perform the cupping therapy. Two points were selected at the back just behind the scapula on the left and right sides; another two points were located in the rump. Cups with 4 oz (125 ml) size with narrow mouths were used. A manual pump (sucking cups) was used to create the negative pressure within the cups during cupping. Arterial and venous blood parameters and serum cortisol concentration were measured before cupping and 3 days and 2, 4, and 8 weeks after cupping. Results: No significant differences were estimated in most hematological and biochemical parameters after cupping. A significant decrease in the concentration of serum cortisol was observed in 3 and 14 days after cupping. Conclusions: Cupping induced minor changes on the hematological and biochemical parameters in Arabian horses. This is the first trial on the effects of wet cupping therapy on the different parameters in Arabian horses, which would be useful for further investigations on the role of complementary therapies in horses. Our further studies will include different disease models.
An Updated Review of the Efficacy of Cupping Therapy
Cao, Huijuan; Li, Xun; Liu, Jianping
2012-01-01
Background Since 1950, traditional Chinese medicine (TCM) cupping therapy has been applied as a formal modality in hospitals throughout China and elsewhere in the world. Based on a previous systematic literature review of clinical studies on cupping therapy, this study presents a thorough review of randomized controlled trials (RCTs) to evaluate the therapeutic effect of cupping therapy. Method Six databases were searched for articles published through 2010. RCTs on cupping therapy for various diseases were included. Studies on cupping therapy combined with other TCM treatments versus non-TCM therapies were excluded. Results 135 RCTs published from 1992 through 2010 were identified. The studies were generally of low methodological quality. Diseases for which cupping therapy was commonly applied were herpes zoster, facial paralysis (Bell palsy), cough and dyspnea, acne, lumbar disc herniation, and cervical spondylosis. Wet cupping was used in most trials, followed by retained cupping, moving cupping, and flash cupping. Meta-analysis showed cupping therapy combined with other TCM treatments was significantly superior to other treatments alone in increasing the number of cured patients with herpes zoster, facial paralysis, acne, and cervical spondylosis. No serious adverse effects were reported in the trials. Conclusions Numerous RCTs on cupping therapy have been conducted and published during the past decades. This review showed that cupping has potential effect in the treatment of herpes zoster and other specific conditions. However, further rigorously designed trials on its use for other conditions are warranted. PMID:22389674
Artificial Intelligence and Information Retrieval.
ERIC Educational Resources Information Center
Teodorescu, Ioana
1987-01-01
Compares artificial intelligence and information retrieval paradigms for natural language understanding, reviews progress to date, and outlines the applicability of artificial intelligence to question answering systems. A list of principal artificial intelligence software for database front end systems is appended. (CLB)
Dimech, George Santiago; Libel, Marlo; de Souza, Wayner Vieira; Cesse, Eduarda; Smolinski, Mark; Oliveira, Wanderson; Albuquerque, Jones
2017-01-01
Background The 2005 International Health Regulations (IHRs) established parameters for event assessments and notifications that may constitute public health emergencies of international concern. These requirements and parameters opened up space for the use of nonofficial mechanisms (such as websites, blogs, and social networks) and technological improvements of communication that can streamline the detection, monitoring, and response to health problems, and thus reduce damage caused by these problems. Specifically, the revised IHR created space for participatory surveillance to function, in addition to the traditional surveillance mechanisms of detection, monitoring, and response. Participatory surveillance is based on crowdsourcing methods that collect information from society and then return the collective knowledge gained from that information back to society. The spread of digital social networks and wiki-style knowledge platforms has created a very favorable environment for this model of production and social control of information. Objective The aim of this study was to describe the use of a participatory surveillance app, Healthy Cup, for the early detection of acute disease outbreaks during the Fédération Internationale de Football Association (FIFA) World Cup 2014. Our focus was on three specific syndromes (respiratory, diarrheal, and rash) related to six diseases that were considered important in a mass gathering context (influenza, measles, rubella, cholera, acute diarrhea, and dengue fever). Methods From May 12 to July 13, 2014, users from anywhere in the world were able to download the Healthy Cup app and record their health condition, reporting whether they were good, very good, ill, or very ill. For users that reported being ill or very ill, a screen with a list of 10 symptoms was displayed. Participatory surveillance allows for the real-time identification of aggregates of symptoms that indicate possible cases of infectious diseases. Results From May 12 through July 13, 2014, there were 9434 downloads of the Healthy Cup app and 7155 (75.84%) registered users. Among the registered users, 4706 (4706/7155, 65.77%) were active users who posted a total of 47,879 times during the study period. The maximum number of users that signed up in one day occurred on May 30, 2014, the day that the app was officially launched by the Minister of Health during a press conference. During this event, the Minister of Health announced the special government program Health in the World Cup on national television media. On that date, 3633 logins were recorded, which accounted for more than half of all sign-ups across the entire duration of the study (50.78%, 3633/7155). Conclusions Participatory surveillance through community engagement is an innovative way to conduct epidemiological surveillance. Compared to traditional epidemiological surveillance, advantages include lower costs of data acquisition, timeliness of information collected and shared, platform scalability, and capacity for integration between the population being served and public health services. PMID:28473308
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2013-01-25
... OFFICE OF THE DIRECTOR OF NATIONAL INTELLIGENCE Agency Information Collection Activities: Extension of Information Collection; Comment Request AGENCY: Office of the Director of National Intelligence... Intelligence (DNI) as Security Executive Agent. Accordingly, ODNI is giving public notice regarding extension...
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2011-07-01
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2010-07-01
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A novel method to assess primary stability of press-fit acetabular cups.
Crosnier, Emilie A; Keogh, Patrick S; Miles, Anthony W
2014-11-01
Initial stability is an essential prerequisite to achieve osseointegration of press-fit acetabular cups in total hip replacements. Most in vitro methods that assess cup stability do not reproduce physiological loading conditions and use simplified acetabular models with a spherical cavity. The aim of this study was to investigate the effect of bone density and acetabular geometry on cup stability using a novel method for measuring acetabular cup micromotion. A press-fit cup was inserted into Sawbones(®) foam blocks having different densities to simulate normal and osteoporotic bone variations and different acetabular geometries. The stability of the cup was assessed in two ways: (a) measurement of micromotion of the cup in 6 degrees of freedom under physiological loading and (b) uniaxial push-out tests. The results indicate that changes in bone substrate density and acetabular geometry affect the stability of press-fit acetabular cups. They also suggest that cups implanted into weaker, for example, osteoporotic, bone are subjected to higher levels of micromotion and are therefore more prone to loosening. The decrease in stability of the cup in the physiological model suggests that using simplified spherical cavities to model the acetabulum over-estimates the initial stability of press-fit cups. This novel testing method should provide the basis for a more representative protocol for future pre-clinical evaluation of new acetabular cup designs. © IMechE 2014.
Effects of hydroxyapatite coating of cups used in hip revision arthroplasty
2012-01-01
Background and purpose Coating of acetabular revision implants with hydroxyapatite (HA) has been proposed to improve ingrowth and stability. We investigated whether HA coating of revision cups can reduce the risk of any subsequent re-revision. Methods We studied uncemented cups either with or without HA coating that were used at a primary acetabular revision and registered in the Swedish Hip Arthroplasty Register (SHAR). 2 such cup designs were identified: Harris-Galante and Trilogy, both available either with or without HA coating. These cups had been used as revision components in 1,780 revisions of total hip arthroplasties (THA) between 1986 and 2009. A Cox proportional hazards model including the type of coating, age at index revision, sex, cause of cup revision, cup design, the use of bone graft at the revision procedure, and the type of cup fixation at primary THA were used to calculate adjusted risk ratios (RRs with 95% CI) for re-revision for any reason or due to aseptic loosening. Results 71% of the cups were coated with HA and 29% were uncoated. At a mean follow-up time of 6.9 (0–24) years, 159 (9%) of all 1,780 cups had been re-revised, mostly due to aseptic loosening (5%), dislocation (2%), or deep infection (1%). HA coating had no significant influence on the risk of re-revision of the cup for any reason (RR = 1.4, CI: 0.9–2.0) or due to aseptic loosening (RR = 1.1, 0.6–1.9). In contrast, HA coating was found to be a risk factor for isolated liner re-revision for any reason (RR = 1.8, CI: 1.01–3.3). Age below 60 years at the index cup revision, dislocation as the cause of the index cup revision, uncemented cup fixation at primary THA, and use of the Harris-Galante cup also increased the risk of re-revision of the cup. In separate analyses in which isolated liner revisions were excluded, bone grafting was found to be a risk factor for re-revision of the metal shell due to aseptic loosening (RR = 2.1, CI: 1.05–4.2). Interpretation We found no evidence to support the notion that HA coating improves the performance of the 2 studied cup designs in revision arthroplasty. In contrast, patient-related factors such as younger age and dislocation as the reason for cup revision, and technical factors such as the choice of revision cup were found to influence the risk of subsequent re-revision of the cup. The reason for inferior results after revision of uncemented cups is not known, but it is possible that these hips more often had pronounced bone loss at the index cup revision. PMID:22937978
Cup Implant Planning Based on 2-D/3-D Radiographic Pelvis Reconstruction-First Clinical Results.
Schumann, Steffen; Sato, Yoshinobu; Nakanishi, Yuki; Yokota, Futoshi; Takao, Masaki; Sugano, Nobuhiko; Zheng, Guoyan
2015-11-01
In the following, we will present a newly developed X-ray calibration phantom and its integration for 2-D/3-D pelvis reconstruction and subsequent automatic cup planning. Two different planning strategies were applied and evaluated with clinical data. Two different cup planning methods were investigated: The first planning strategy is based on a combined pelvis and cup statistical atlas. Thereby, the pelvis part of the combined atlas is matched to the reconstructed pelvis model, resulting in an optimized cup planning. The second planning strategy analyzes the morphology of the reconstructed pelvis model to determine the best fitting cup implant. The first planning strategy was compared to 3-D CT-based planning. Digitally reconstructed radiographs of THA patients with differently severe pathologies were used to evaluate the accuracy of predicting the cup size and position. Within a discrepancy of one cup size, the size was correctly identified in 100% of the cases for Crowe type I datasets and in 77.8% of the cases for Crowe type II, III, and IV datasets. The second planning strategy was analyzed with respect to the eventually implanted cup size. In seven patients, the estimated cup diameter was correct within one cup size, while the estimation for the remaining five patients differed by two cup sizes. While both planning strategies showed the same prediction rate with a discrepancy of one cup size (87.5%), the prediction of the exact cup size was increased for the statistical atlas-based strategy (56%) in contrast to the anatomically driven approach (37.5%). The proposed approach demonstrated the clinical validity of using 2-D/3-D reconstruction technique for cup planning.
76 FR 62630 - Information Security Regulations
Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-11
... CENTRAL INTELLIGENCE AGENCY 32 CFR Part 1902 Information Security Regulations AGENCY: Central Intelligence Agency. ACTION: Final rule. SUMMARY: The Central Intelligence agency is removing certain information security regulations which have become outdated. The Executive Order upon which the regulations...
Six Information Technology Services Contracts for the Defense Intelligence Community
2000-04-24
This category covers Defense Intelligence Community organizations whose mission is to provide for the planning, development, deployment, operation ... management , and oversight of global information networks and infrastructure supporting intelligence producers. • Information Systems. This category
... pasta, or cereal Vegetables 4-5 1 cup raw leafy vegetables ½ cup cooked vegetables 6 oz vegetable juice Fruits 4-5 1 medium fruit ¼ cup dried fruit ½ cup fresh, frozen, or canned fruit ½ cup fruit juice Low-fat or fat-free milk and milk products 2- ...
New is the well-forgotten old: The use of dry cupping in musculoskeletal medicine.
Rozenfeld, Evgeni; Kalichman, Leonid
2016-01-01
Cupping is an ancient technique used in treating pain and various disorders. Different techniques have been developed over time, however, applying a cup to create suction over a painful area, is common to all. Dry or fire cupping, used on the intact skin, leaves bluish circular hematomas. Recently, interest in cupping has re-emerged and subsequently, several studies have begun to investigate the mechanisms of cupping therapy. Mechanically, cupping increases blood circulation, whereas physiologically it activates the immune system and stimulates the mechanosensitive fibers, thus leading to a reduction in pain. There is initial scientific evidence that dry cupping is able to reduce musculoskeletal pain. Since cupping is an inexpensive, noninvasive and low-risk (if performed by a trained practitioner) therapeutic modality, we believe that it should be included in the arsenal of musculoskeletal medicine. It is essential to perform additional studies clarifying the biological mechanism and clinical effects of cupping. Copyright © 2015 Elsevier Ltd. All rights reserved.
MacLennan, Donald A.; Turner, Brian P.; Gitsevich, Aleksandr; Bass, Gary K.; Dolan, James T.; Kipling, Kent; Kirkpatrick, Douglas A.; Leng, Yongzhang; Levin, Izrail; Roy, Robert J.; Shanks, Bruce; Smith, Malcolm; Trimble, William C.; Tsai, Peter
2001-01-01
A jacketed lamp bulb envelope includes a ceramic cup having an open end and a partially closed end, the partially closed end defining an aperture, a lamp bulb positioned inside the ceramic cup abutting the aperture, and a reflective ceramic material at least partially covering a portion of the bulb not abutting the aperture. The reflective ceramic material may substantially fill an interior volume of the ceramic cup not occupied by the bulb. The ceramic cup may include a structural feature for aiding in alignment of the jacketed lamp bulb envelope in a lamp. The ceramic cup may include an external flange about a periphery thereof. One example of a jacketed lamp bulb envelope includes a ceramic cup having an open end and a closed end, a ceramic washer covering the open end of the ceramic cup, the washer defining an aperture therethrough, a lamp bulb positioned inside the ceramic cup abutting the aperture, and a reflective ceramic material filling an interior volume of the ceramic cup not occupied by the bulb. A method of packing a jacketed lamp bulb envelope of the type comprising a ceramic cup with a lamp bulb disposed therein includes the steps of filling the ceramic cup with a flowable slurry of reflective material, and applying centrifugal force to the cup to pack the reflective material therein.
Liu, Feng; Williams, Sophie; Jin, Zhongmin; Fisher, John
2013-11-01
Head contact on the rim of the cup causes stress concentration and consequently increased wear. The head contact on the rim of the cup may in addition cause an offset load and torque on the cup. The head-rim contact resulting from microseparation or subluxation has been investigated. An analytical model has been developed to calculate the offset loading and resultant torque on the cup as a function of the translational displacement of the head under simplified loading condition of the hip joint at heel strike during a walking cycle. The magnitude of the torque on the cup was found to increase with the increasing translational displacement, larger diameter heads, eccentric cups, and the coefficient of friction of the contact. The effects of cup inclination, cup rim radius, and cup coverage angle on the magnitude of the torque were found to be relatively small with a maximum variation in the torque magnitude being lower than 20%. This study has shown an increased torque due to the head loading on the rim of the cup, and this may contribute to the incidence of cup loosening. Particularly, metal-on-metal hip joints with larger head diameters may produce the highest offset loading torque.
Intelligence, Dataveillance, and Information Privacy
NASA Astrophysics Data System (ADS)
Mace, Robyn R.
The extent and scope of intelligence activities are expanding in response to technological and economic transformations of the past decades. Intelligence efforts involving aggregated data from multiple public and private sources combined with past abuses of domestic intelligence functions have generated significant concerns among privacy advocates and citizens about the protection of individual civil liberties and information privacy from corporate and governmental misuse. In the information age, effective regulation and oversight are key components in the legitimacy and success of government domestic intelligence activities.
Tribology and wear of metal-on-metal hip prostheses: influence of cup angle and head position.
Williams, Sophie; Leslie, Ian; Isaac, Graham; Jin, Zhongmin; Ingham, Eileen; Fisher, John
2008-08-01
Clinical studies have indicated that the angular position of the acetabular cup may influence wear in metal-on-metal total hip bearings. A high cup angle in comparison to the anatomical position may lead to the head being constrained by the superior lateral surface and rim of the cup, thus potentially changing the location of the contact zone between the head and the cup. The aim of this study was to test the hypothesis that both a steep cup angle and a lateralized position of the head can increase head contact on the superior rim of the cup, with the consequence of increased wear. Hip-joint simulator studies of metal-on-metal bearings were undertaken with cup angles of 45 degrees and 55 degrees . The femoral head was either aligned to the center of the cup or placed in a position of microlateralization. Wear was measured gravimetrically over 5 million cycles. A steep cup angle of 55 degrees showed significantly higher long-term steady-state wear than a standard cup angle of 45 degrees (p < 0.01). The difference was fivefold. Microlateralization of the head resulted in a fivefold increase in steady-state wear compared with a centralized head. The combination of a steep cup angle and a microlateralized head increased the steady-state wear rate by tenfold compared with a standard cup angle with a centralized head. These studies support the hypothesis that both an increased cup angle and a lateral head position increase wear in metal-on-metal hip prostheses.
History of cupping (Hijama): a narrative review of literature.
Qureshi, Naseem Akhtar; Ali, Gazzaffi Ibrahim; Abushanab, Tamer Shaban; El-Olemy, Ahmed Tawfik; Alqaed, Meshari Saleh; El-Subai, Ibrahim S; Al-Bedah, Abdullah M N
2017-05-01
Cupping (Hijama in Arabic) is an ancient, holistic method for the treatment of a variety of diseases. Though the exact origin of cupping therapy is a matter of controversy, its use has been documented in early Egyptian and Chinese medical practices. Diverse human civilizations have contributed to the historical development and continuation of cupping therapy. This narrative review describes the history of cupping, historical definitions, cupping instruments and uses of cupping therapy. Electronic searches of relevant databases (PubMed, Google Scholar and OvidSP) were conducted using keywords and Boolean operators. Manual searches and references of published articles and books were also conducted. A number of articles (N = 625) were retained for extensive review, and finally 83 articles were included in this paper. The historical descriptions of cupping therapy were found in ancient human civilizations of the Eastern and Western world. There were inconsistent data concerning the origin of cupping, definitions, instruments, procedures, definite advancements and research in Hijama over centuries. Cupping therapy fell out of favor in 17th and mid-18th centuries but recovered popularity in modern medicine. Currently, cupping therapy is used for health promotion, prophylaxis and treatment of a variety of diseases around the world. Cupping therapy with a good safety profile has a checkered history and is a well-recognized traditional method for managing medical conditions. Currently, the scope of cupping therapy is expanding, and a growing body of research is providing additional evidence-based data for the further advancement of cupping therapy in the treatment of a variety of diseases.
Acetabular cup position and risk of dislocation in primary total hip arthroplasty.
Seagrave, Kurt G; Troelsen, Anders; Malchau, Henrik; Husted, Henrik; Gromov, Kirill
2017-02-01
Background and purpose - Hip dislocation is one of the most common complications following total hip arthroplasty (THA). Several factors that affect dislocation have been identified, including acetabular cup positioning. Optimal values for cup inclination and anteversion are debatable. We performed a systematic review to describe the different methods for measuring cup placement, target zones for cup positioning, and the association between cup positioning and dislocation following primary THA. Methods - A systematic search of literature in the PubMed database was performed (January and February 2016) to identify articles that compared acetabular cup positioning and the risk of dislocation. Surgical approach and methods for measurement of cup angles were also considered. Results - 28 articles were determined to be relevant to our research question. Some articles demonstrated that cup positioning influenced postoperative dislocation whereas others did not. The majority of articles could not identify a statistically significant difference between dislocating and non-dislocating THA with regard to mean angles of cup anteversion and inclination. Most of the articles that assessed cup placement within the Lewinnek safe zone did not show a statistically significant reduction in dislocation rate. Alternative target ranges have been proposed by several authors. Interpretation - The Lewinnek safe zone could not be justified. It is difficult to draw broad conclusions regarding a definitive target zone for cup positioning in THA, due to variability between studies and the likely multifactorial nature of THA dislocation. Future studies comparing cup positioning and dislocation rate should investigate surgical approach separately. Standardized tools for measurement of cup positioning should be implemented to allow comparison between studies.
Acetabular cup position and risk of dislocation in primary total hip arthroplasty
Seagrave, Kurt G; Troelsen, Anders; Malchau, Henrik; Husted, Henrik; Gromov, Kirill
2017-01-01
Background and purpose — Hip dislocation is one of the most common complications following total hip arthroplasty (THA). Several factors that affect dislocation have been identified, including acetabular cup positioning. Optimal values for cup inclination and anteversion are debatable. We performed a systematic review to describe the different methods for measuring cup placement, target zones for cup positioning, and the association between cup positioning and dislocation following primary THA. Methods — A systematic search of literature in the PubMed database was performed (January and February 2016) to identify articles that compared acetabular cup positioning and the risk of dislocation. Surgical approach and methods for measurement of cup angles were also considered. Results— 28 articles were determined to be relevant to our research question. Some articles demonstrated that cup positioning influenced postoperative dislocation whereas others did not. The majority of articles could not identify a statistically significant difference between dislocating and non-dislocating THA with regard to mean angles of cup anteversion and inclination. Most of the articles that assessed cup placement within the Lewinnek safe zone did not show a statistically significant reduction in dislocation rate. Alternative target ranges have been proposed by several authors. Interpretation— The Lewinnek safe zone could not be justified. It is difficult to draw broad conclusions regarding a definitive target zone for cup positioning in THA, due to variability between studies and the likely multifactorial nature of THA dislocation. Future studies comparing cup positioning and dislocation rate should investigate surgical approach separately. Standardized tools for measurement of cup positioning should be implemented to allow comparison between studies. PMID:27879150
Recommended Dietary Menus for Use in Operational and Research Saturation Diving
1991-05-01
GMS MARGARINE-CORN-REG 1.0 TBSP 14.1 GMS CAKE-POUND 1.0 SLICE 33.0 GMS SNACK RAISINS-SEEDLESS 0.7 CUP 108.8 GMS NUTS - CASHEWS -DRY ROASTED 0.2 CUP 34.3...CUP 250.0 GMS TEA-INSTANT-PREP-UNSWEET 2.0 CUPS 474.0 GMS MARGARINE-CORN-REG 1.0 TBSP 14.1 GMS SNACK NUTS - CASHEWS -OIL ROASTED 0.3 CUP 39.0 GMS...GMS SNACK RAISINS-SEEDLESS 0.7 CUP 108.8 GMS NUTS - CASHEWS -DRY ROASTED 0.3 CUP 41.1 GMS NUTRIENT VALUES Kcalories 3694 Kc Carbohydrate 545.0 Gm Protein
Alternative medicine: an update on cupping therapy.
Chen, B; Li, M-Y; Liu, P-D; Guo, Y; Chen, Z-L
2015-07-01
To know the research progress of cupping therapy all over the world, the authors analyze the research of cupping therapy in recent 5 years. It indicates that cupping therapy can be applied to extensive curable disease, but has poor clinical evidence. Some improvements in the mechanism research of cupping therapy have been made, but it needs further research. The adverse events of cupping therapy attract attention. The standardization of cupping therapy has emerged. © The Author 2014. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved. For Permissions, please email: journals.permissions@oup.com.
Ozden, Vahit Emre; Dikmen, Goksel; Beksac, Burak; Tozun, Ismail Remzi
2018-05-01
Placement of acetabular cup in the dysplastic hip is a challenging procedure. Using bulk femoral head autograft to increase the bony coverage of the cup is one of the techniques, which have been described. The impact of cup position on cup and autograft survival is a controversial issue. We aimed to determine whether the position of cementless acetabular cup used in conjunction with femoral head autograft in dysplastic hips affected the autograft-host incorporation with its final radiographic appearance and the cup survivorship into the second decade. Thirty-eight dysplastic hips with varying Crowe types in 31 patients (30 women and one man) were included. The mean age was 47 years (range, 29-64 years) and the mean follow-up was 20.3 years (range, 14.8-25.9 years). The initial postoperative and final radiographs were evaluated. The survival rate of the cups was analysed using Kaplan-Meier statistics and the log-rank test. Multivariate analysis was used to evaluate the effect of variables (Crowe type, radiographic initial host bone coverage over the cup and position of the cup) on survivorship. The acetabular cups were positioned anatomical in 27/38 hips according to Ranawat measurement technique. Trabecular bridging at graft-host interface was seen in all cases at an average 22.1 months. Neither acetabular cup position nor initial host bone coverage over acetabular cup less than 50% had any significant effect on either cup survival or final radiographic appearance of the graft. The 20-year cup survival rate without aseptic revision was 66% (95 CI, 52%-84%). No revision was performed due to graft resorption. Twenty-year survival rate of the cementless cup combination with femoral head autograft showed no significant differences whether it was placed at high or anatomic hip centre. The final radiographic appearance of the autograft was not affected from either the cup location or the initial radiographic horizontal host bone coverage. Copyright © 2018 The Japanese Orthopaedic Association. Published by Elsevier B.V. All rights reserved.
When is Information Sufficient for Action Search with Unreliable Yet Informative Intelligence
2016-03-30
information: http://pubsonline.informs.org When Is Information Sufficient for Action? Search with Unreliable yet Informative Intelligence Michael Atkinson... Search with Unreliable yet Informative Intelligence. Operations Research Published online in Articles in Advance 30 Mar 2016 . http://dx.doi.org/10.1287...print) � ISSN 1526-5463 (online) http://dx.doi.org/10.1287/opre.2016.1488 © 2016 INFORMS When Is Information Sufficient for Action? Search with
76 FR 59071 - Freedom of Information Act Regulations
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-23
... CENTRAL INTELLIGENCE AGENCY 32 CFR Part 1900 Freedom of Information Act Regulations AGENCY: Central Intelligence Agency. ACTION: Proposed rule. SUMMARY: Consistent with the Freedom of Information...,'' and Executive Orders 13526 and 13392, the Central Intelligence Agency (CIA) has undertaken and...
Artificial Intelligence Information Sources for the Beginner and Expert
1991-05-01
SUBPLEETAR TMS T bepbhdi" Artificial Intelligence ApplictionsforMlitar Expertis SystemsWilasbrVA 527Mrh 91 12a. DSCRIBTION C AIITY 6 STAEENRTY CTO SECb.T...DLSIFC ISTR BUMATION OC Apnclassified pu ncrlase; ituied inlsife unlimited. Artificial Intelligence Information Sources for the Beginner and Expert...mgivenfdsac.dia.mil UUCP: {...).osu-cisidsac!mgiven ABSTRACT A tremendous amount of information on artificial intelligence is available via different
Blanck, Heidi M.; Sherry, Bettylou; Park, Sohyun; Nebeling, Linda; Yaroch, Amy L.
2013-01-01
Introduction Water is vital for life, and plain water is a calorie-free option for hydration. Increasing consumption of drinking water is a strategy to reduce energy intake and lose or maintain weight; however, information on the characteristics of consumers who drink water is limited. Our objective was to describe the characteristics of people who have a low intake of drinking water and to determine associations between their behaviors and attitudes and their intake of water. Methods We analyzed data from a nationally representative sample of 3,397 US adults who participated in the National Cancer Institute’s 2007 Food Attitudes and Behaviors Survey. Multivariable logistic regression was used to identify sociodemographic characteristics and health-related behaviors and attitudes associated with self-reported drinking water intake of less than 4 cups per day. Results Overall, 7% of adults reported no daily consumption of drinking water, 36% reported drinking 1 to 3 cups, 35% reported drinking 4 to 7 cups, and 22% reported drinking 8 cups or more. The likelihood of drinking less than 4 cups of water daily was significantly higher among participants aged 55 years or older than among those aged 18 to 34 (adjusted odds ratio [AOR], 1.3), among residents of the Northeast than among residents of the South (AOR, 1.4), among participants who consumed 1 cup or less of fruits or vegetables per day than among those who consumed 4.5 cups or more (AOR, 3.0), among participants who did not exercise than among those who exercised 150 minutes or more per week (AOR, 1.7), and among participants who were neither trying to gain nor lose weight than among those trying to lose weight (AOR, 1.3). Conclusion Low drinking water intake was associated with age, region of residence, and several unhealthful behaviors and attitudes. Understanding characteristics associated with low drinking water intake may help to identify populations that could benefit from interventions to help adults drink more water. PMID:23578399
Use and abuse of medication during 2014 FIFA World Cup Brazil: a retrospective survey
Vaso, Martin; Weber, Alexis; Tscholl, Philippe M; Junge, Astrid; Dvorak, Jiri
2015-01-01
Objective To examine the use of medication of top-level male players during the 2014 FIFA World Cup Brazil. Design Retrospective survey. Participants/information 736 top level players. Setting The teams’ physicians disclosed a list of the medications used by each player within 72 h before each match of the 2014 FIFA World Cup Brazil. Outcome measures Average number of medications used per player per match or during the tournament; average number and percentage of players using at least one medication per match or during the tournament. Results 67.0% of all players took various types of medication during the tournament. The most used medications during the tournament were non-steroidal anti-inflammatory drugs (NSAIDs), by 54.2% of all players, followed by analgaesics (12.6%); β-2 agonists were only used by 0.5%. On average, 0.8 medications per player were used before each match. More players were reported taking medications during the knockout round than during the qualification round (0.36±0.48 vs 0.49±0.50, p<0.001). Players from the South American and Asian Confederations took twice as many medications per match as players from the African Confederation (1.17±1.55 and 1.01±1.26 vs 0.48±0.69, both p<0.001). Conclusions There was high use of NSAIDs during the 2014 FIFA World Cup. Although the intake of NSAIDs per match (0.35±0.46 vs 0.31±0.48, p<0.01) in the 2014 FIFA World Cup decreased compared to the 2010 FIFA World Cup, the average use was still higher than in the 2006 FIFA World Cup, and the average number of all used medications per player remained the same level as 4 years prior, with all its implications for the player's health. More efforts need to be undertaken worldwide in order to reduce the administration of medications in sports, through continuous education for players, starting from a young age, as well as for doctors and paramedics. PMID:26359283
Biometry and spectral domain optical coherence tomography parameters in children with large cupping.
Jung, Jong Jin; Baek, Seung-Hee; Kim, Ungsoo Samuel
2013-09-01
The purpose of this study is to investigate optic nerve head using spectral domain optical coherence tomography (SD-OCT) in children with large cupping. 111 eyes (4-10 years) were divided into three groups according to the cup to disc ratio: group 1, ≤0.3; group 2, 0.4-0.6; and group 3, ≥0.7. The rim area, disc area, average cup to disc ratio, vertical cup to disc ratio, and cup volume were investigated using SD-OCT (Cirrus HD-OCT, Carl Zeiss, Jena, Germany), and the axial length and anterior chamber depth (ACD) were measured by IOL master (IOL master 500, Carl Zeiss, Jena, Germany). Next, we compared ocular biometry and SD-OCT between the three groups. The mean age of group 1 was 6.48 ± 1.42 years, 7.00 ± 1.75 years in group 2, and 6.63 ± 1.82 years in group 3 (p = 0.370). A significant difference was seen in the spherical equivalent between the groups (p = 0.001). Group 2 had the most myopic refractive errors. As the cup to disc ratio increases, disc area, average cup to disc ratio, vertical cup to disc ratio, and cup volume increase significantly. When the results of ocular biometry and SD-OCT are adjusted for axial length, only disc area showed a significant correlation with cup to disc ratio (ACD: p = 0.473, rim area: p = 0.639, disc area: p = 0.005, and cup volume: p = 0.325). Axial length is the key factor determining disc size, which in turn is important for determining cup to disc ratio. Normal children with large cupping should be examined for axial length, myopic refractive errors, and disc size.
Nie, Yong; Wang, HaoYang; Huang, ZeYu; Shen, Bin; Kraus, Virginia Byers; Zhou, Zongke
2018-01-01
The accuracy of using 2-dimensional anteroposterior pelvic radiography to assess acetabular cup coverage among patients with developmental dysplasia of the hip after total hip arthroplasty (THA) remains unclear in retrospective clinical studies. A group of 20 patients with developmental dysplasia of the hip (20 hips) underwent cementless THA. During surgery but after acetabular reconstruction, bone wax was pressed onto the uncovered surface of the acetabular cup. A surface model of the bone wax was generated with 3-dimensional scanning. The percentage of the acetabular cup that was covered by intact host acetabular bone in vivo was calculated with modeling software. Acetabular cup coverage also was determined from a postoperative supine anteroposterior pelvic radiograph. The height of the hip center (distance from the center of the femoral head perpendicular to the inter-teardrop line) also was determined from radiographs. Radiographic cup coverage was a mean of 6.93% (SD, 2.47%) lower than in vivo cup coverage for these 20 patients with developmental dysplasia of the hip (P<.001). However, both methods yielded highly correlated measurements for cup coverage (Pearson r=0.761, P<.001). The size of the acetabular cup (P=.001) but not the position of the hip center (high vs normal) was significantly associated with the difference between radiographic and in vivo cup coverage. Two-dimensional radiographically determined cup coverage conservatively reflects in vivo cup coverage and remains an important index (taking 7% underestimation errors and the effect of greater underestimation of larger cup size into account) for assessing the stability of the cup and monitoring for adequate ingrowth of bone. [Orthopedics. 2018; 41(1):e46-e51.]. Copyright 2017, SLACK Incorporated.
Liu, Zhidan; Chen, Chunlan; Li, Xiaoyan; Zhao, Chuang; Li, Zunyuan; Liang, Wei; Lin, Yufang
2018-02-01
Cupping therapy has a long history in traditional medicine especially in Asian countries. It was controversial whether cupping induced blisters are beneficial to healing effects, and the formation and content in the blisters remain unexplored. We aimed to identify and compare the molecular components of the blister fluid from the cupping therapy and the scalds to explore the necessary of inducing cupping induced blisters. Fluid sample of blisters from fifteen patients receiving cupping therapy (Cupping group) and scald burns (Scald group) were collected in this study. Proteins from the blisters were separated by two-dimensional electrophoresis (2D-gel) and further analyzed by mass spectrometry. In addition, the changes in particular proteins were confirmed by Western blotting. The protein components are significantly different between blister from cupping therapy and scalds. The immune responses, oxidative stress and metabolic related proteins (Ig lambda-2 chain C regions, Ig gamma-1 chain C region, hemopexin, prdx2, calmodulin, succinyl-CoA ligase and tetranectin) were increased, whereas the hemoglobin subunit beta was decreased in the Cupping group compared with the Scald group. Cupping induced blisters contain several proteins which relate to the activation of certain immune pathways including anti-oxidation, anti-apoptosis, tissue repairing and metabolic regulation. This proteomic analysis may indicate a significant clue to the mechanism study of cupping. Copyright © 2017 Elsevier Ltd. All rights reserved.
Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-17
...] Special Local Regulation and Safety Zone; America's Cup Sailing Events, San Francisco, CA AGENCY: Coast... regulation and temporary safety zone proposed for those portions of the ``America's Cup World Series,'' the ``Louis Vuitton Cup'' challenger selection series, and the ``America's Cup Finals Match'' sailing regattas...
78 FR 36426 - Safety Zone; Queen's Cup; Lake Michigan; Milwaukee, WI
Federal Register 2010, 2011, 2012, 2013, 2014
2013-06-18
...-AA00 Safety Zone; Queen's Cup; Lake Michigan; Milwaukee, WI AGENCY: Coast Guard, DHS. ACTION: Temporary... Lake Michigan due to the 2013 Queen's Cup Race. This temporary safety zone is necessary to protect the... Queen's Cup Regatta. The Queen's Cup Regatta is a race from Milwaukee, WI to Ludington, MI that is...
Exploring Volumetrically Indexed Cups
ERIC Educational Resources Information Center
Jones, Dustin L.
2011-01-01
This article was inspired by a set of 12 cylindrical cups, which are volumetrically indexed; that is to say, the volume of cup "n" is equal to "n" times the volume of cup 1. Various sets of volumetrically indexed cylindrical cups are explored. I demonstrate how this children's toy is ripe for mathematical investigation, with connections to…
Effect of Seed Density on Splash Cup Seed Dispersal
NASA Astrophysics Data System (ADS)
Wigger, Patrick; Pepper, Rachel
2017-11-01
Splash cup plants are plants that utilize a small, mm-sized cup filled with seeds as a method of seed dispersal. The cup uses kinetic energy of an incident raindrop in order to project the seeds away from the plant up to 1 meter. The dispersal distance is important to ensure the offspring are not clustered too tightly to the parent plant. It has previously been found that a cup angle of 40 degrees to the horizontal is optimal for maximum dispersal of water from cups with no seeds. In this study we examine if the 40 degree cup is optimal for cups containing seeds with varying densities. We released uniform water drops above 5.0 mm 3D printed models of splash cups, using 1.0 mm plastic and glass microspheres of varying densities to simulate seeds. We observed the dispersal characteristics of each bead type by measuring the final seed locations after each splash, and by recording high speed video to determine the angle and velocity of the seeds as they exited the cup.
Intelligent Information Retrieval: An Introduction.
ERIC Educational Resources Information Center
Gauch, Susan
1992-01-01
Discusses the application of artificial intelligence to online information retrieval systems and describes several systems: (1) CANSEARCH, from MEDLINE; (2) Intelligent Interface for Information Retrieval (I3R); (3) Gausch's Query Reformulation; (4) Environmental Pollution Expert (EP-X); (5) PLEXUS (gardening); and (6) SCISOR (corporate…
The intelligent user interface for NASA's advanced information management systems
NASA Technical Reports Server (NTRS)
Campbell, William J.; Short, Nicholas, Jr.; Rolofs, Larry H.; Wattawa, Scott L.
1987-01-01
NASA has initiated the Intelligent Data Management Project to design and develop advanced information management systems. The project's primary goal is to formulate, design and develop advanced information systems that are capable of supporting the agency's future space research and operational information management needs. The first effort of the project was the development of a prototype Intelligent User Interface to an operational scientific database, using expert systems and natural language processing technologies. An overview of Intelligent User Interface formulation and development is given.
Retinal and anterior eye compartments derive from a common progenitor pool in the avian optic cup
Venters, Sara J.; Cuenca, Paulina D.
2011-01-01
Purpose The optic cup is created through invagination of the optic vesicle. The morphogenetic rearrangement creates a double-layered cup, with a hinge (the Optic Cup Lip) where the epithelium bends back upon itself. Shortly after the optic cup forms, it is thought to be sub-divided into separate lineages: i) pigmented epithelium in the outer layer; ii) presumptive iris and ciliary body at the most anterior aspect of the inner layer; and iii) presumptive neural retina in the remainder of the inner layer. We test the native developmental potential of the anterior cup to determine if it normally contributes to the retina. Methods Vital dye and green fluorescent protein (GFP) expressing replication-incompetent retroviral vectors were used to label cells in the nascent optic cup and follow their direct progeny throughout development. Label was applied to either the optic cup lip (n=40), or to the domain just posterior to the lip (n=20). Retroviral labeling is a permanent lineage marker and enabled the analysis of advanced stages of development. Results Labeling within the optic cup gave rise to labeled progeny in the posterior optic cup that differentiated as neural retina (20 of 20). In contrast, labeling cells in the optic cup lip gave rise to progeny of labeled cells arrayed in a linear progression, from the lip into the neural retina (36 of 40). Label was retained in cells at the optic cup lip, regardless of age at examination. In older embryos, labeled progeny delaminated from the optic cup lip to differentiate as muscle of the pupillary margin. Conclusions The data show that the cells at the optic cup lip are a common progenitor population for pigmented epithelium, anterior eye tissues (ciliary body, iris, and pupillary muscle) and retinal neurons. The findings are supportive of an interpretation where the optic cup lip is a specialized niche containing a multipotent progenitor population. PMID:22219630
ERIC Educational Resources Information Center
Cole, Charles
1998-01-01
Suggests that the principles underlying the procedure used by doctors to diagnose a patient's disease are useful in the design of intelligent information-retrieval systems because the task of the doctor is conceptually similar to the computer or human intermediary's task in information retrieval: to draw out the user's query/information need.…
NASA Technical Reports Server (NTRS)
2004-01-01
KENNEDY SPACE CENTER, FLA. In the Orbiter Processing Facility, Mike Bolt holds the Stanley Cup, won this year by the National Hockey Leagues Tampa Bay Lightning. Bolt is the Stanley Cup keeper. The cup was also briefly available for viewing by employees in the KSC Training Auditorium. Jay Feaster, general manager of the Tampa Bay Lightning, brought the cup to KSC while on a tour. The Stanley Cup weighs 35 pounds and is more than 100 years old. The Lightning will be added to the cup in September.
Factitious panniculitis induced by cupping therapy.
Moon, Suk-Ho; Han, Hyun-Ho; Rhie, Jong-Won
2011-11-01
Cupping therapy is an alternative medical procedure that has been widely performed in Asian countries to relieve pain. It is known that there is no complication to this therapy, so many non-health care professionals have performed this procedure. However, there have been few reports on complications, such as iron deficiency anemia, hemorrhagic bullae, kelloids, vasovagal syncope, and foreign body reactions. Masses associated with panniculitis induced by cupping are extremely rare, and they require a unique approach.A 56-year-old woman presented with a 10-month history of multiple masses in the posterior neck and right shoulder areas. The patient repeatedly attempted cupping therapy by herself, and multiple palpable masses developed in the posterior neck and right shoulder area where cupping therapy had been performed. The masses were enlarged by repeated cupping, and they decreased in size when cupping was stopped. Among all lesions, the 2 masses with tenderness were surgically excised. The remaining masses resolved after cupping therapy was ceased. When a patient with subcutaneous mass has a history of cupping or trace of cupping marks, panniculitis induced by cupping should be suspected. The lesion seems to spontaneously resolve unless they are repeatedly stimulated. However, surgical resection is considered in patients with infections or severe tenderness as a complication.
75 FR 37253 - Classified National Security Information
Federal Register 2010, 2011, 2012, 2013, 2014
2010-06-28
..., Intelligence, National defense, National security information, Presidential documents, Security information... reveal the identity of a confidential human source or a human intelligence source or key design concepts... or a human intelligence source, the duration shall be up to 75 years and shall be designated with the...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-01-30
...] RIN 1625-AA00; 1625-AA08 Special Local Regulation and Safety Zone; America's Cup Sailing Events, San... those portions of the ``America's Cup World Series,'' the ``Louis Vuitton Cup'' challenger selection series, and the ``America's Cup Finals Match'' sailing regattas that may be conducted in the waters of...
Fink, B
2015-04-01
Tripolar cups can be separated into constrained and unconstrained dual-mobility cups. The latter show better survival and revision rates. The main problem is the polyethylene wear. Therefore modern types of polyethylene are used in these cups. The indications for dual-mobility cups are recurrent dislocation and situations where the risk of dislocation is increased. Georg Thieme Verlag KG Stuttgart · New York.
An overview of Compassionate Use Programs in the European Union member states.
Balasubramanian, Gayathri; Morampudi, Suman; Chhabra, Pankdeep; Gowda, Arun; Zomorodi, Behsad
2016-11-01
The past decade witnessed rapid development of novel drugs and therapeutic biological agents. The marketing authorization for novel therapies is often time consuming and distressing for patients. Earlier clinical trials were the only way to access new drugs under development. However, not every patient meets the enrolment criteria, and participation is difficult for patients with life-threatening, long-lasting or seriously debilitating diseases like rare diseases. Early access programs like "Compassionate Use Program (CUP)" have generated alternative channels for such patients. The European Medical Agency provides regulations and recommendations for compassionate use, upon which every European Union (EU) member state has developed its own rules and regulations. Despite previous reviews and studies, the available information is limited and gaps exist. This literature review explores CUP in 28 EU member states. Data was collected through literature review and use of country-specific search terms from the healthcare domain. Data sources were not limited to databases and articles published in journals, but also included grey literature. The results implied that CUP was present in 20 EU member states (71%). Of 28 EU states, 18 (∼64%) had nationalized regulations and processes were well-defined. Overall, this review identified CUP and its current status and legislation in 28 EU member states. The established legislation for CUP in the EU member states suggest their willingness to adopt processes that facilitate earlier and better access to new medicines. Further research and periodic reviews are warranted to understand the contemporary and future regulatory trends in early access programs.
Predictability, Force and (Anti-)Resonance in Complex Object Control.
Maurice, Pauline; Hogan, Neville; Sternad, Dagmar
2018-04-18
Manipulation of complex objects as in tool use is ubiquitous and has given humans an evolutionary advantage. This study examined the strategies humans choose when manipulating an object with underactuated internal dynamics, such as a cup of coffee. The object's dynamics renders the temporal evolution complex, possibly even chaotic, and difficult to predict. A cart-and-pendulum model, loosely mimicking coffee sloshing in a cup, was implemented in a virtual environment with a haptic interface. Participants rhythmically manipulated the virtual cup containing a rolling ball; they could choose the oscillation frequency, while the amplitude was prescribed. Three hypotheses were tested: 1) humans decrease interaction forces between hand and object; 2) humans increase the predictability of the object dynamics; 3) humans exploit the resonances of the coupled object-hand system. Analysis revealed that humans chose either a high-frequency strategy with anti-phase cup-and-ball movements or a low-frequency strategy with in-phase cup-and-ball movements. Counter Hypothesis 1, they did not decrease interaction force; instead, they increased the predictability of the interaction dynamics, quantified by mutual information, supporting Hypothesis 2. To address Hypothesis 3, frequency analysis of the coupled hand-object system revealed two resonance frequencies separated by an anti-resonance frequency. The low-frequency strategy exploited one resonance, while the high-frequency strategy afforded more choice, consistent with the frequency response of the coupled system; both strategies avoided the anti-resonance. Hence, humans did not prioritize interaction force, but rather strategies that rendered interactions predictable. These findings highlight that physical interactions with complex objects pose control challenges not present in unconstrained movements.
NASA Astrophysics Data System (ADS)
Sharma, Archie; Corona, Enrique; Mitra, Sunanda; Nutter, Brian S.
2006-03-01
Early detection of structural damage to the optic nerve head (ONH) is critical in diagnosis of glaucoma, because such glaucomatous damage precedes clinically identifiable visual loss. Early detection of glaucoma can prevent progression of the disease and consequent loss of vision. Traditional early detection techniques involve observing changes in the ONH through an ophthalmoscope. Stereo fundus photography is also routinely used to detect subtle changes in the ONH. However, clinical evaluation of stereo fundus photographs suffers from inter- and intra-subject variability. Even the Heidelberg Retina Tomograph (HRT) has not been found to be sufficiently sensitive for early detection. A semi-automated algorithm for quantitative representation of the optic disc and cup contours by computing accumulated disparities in the disc and cup regions from stereo fundus image pairs has already been developed using advanced digital image analysis methodologies. A 3-D visualization of the disc and cup is achieved assuming camera geometry. High correlation among computer-generated and manually segmented cup to disc ratios in a longitudinal study involving 159 stereo fundus image pairs has already been demonstrated. However, clinical usefulness of the proposed technique can only be tested by a fully automated algorithm. In this paper, we present a fully automated algorithm for segmentation of optic cup and disc contours from corresponding stereo disparity information. Because this technique does not involve human intervention, it eliminates subjective variability encountered in currently used clinical methods and provides ophthalmologists with a cost-effective and quantitative method for detection of ONH structural damage for early detection of glaucoma.
Affatato, Saverio; Zanini, Filippo; Carmignato, Simone
2017-01-01
Wear is currently quantified as mass loss of the bearing materials measured using gravimetric methods. However, this method does not provide other information, such as volumetric loss or surface deviation. In this work, we validated a technique to quantify polyethylene wear in three different batches of ultrahigh-molecular-polyethylene acetabular cups used for hip implants using nondestructive microcomputed tomography. Three different configurations of polyethylene acetabular cups, previously tested under the ISO 14242 parameters, were tested on a hip simulator for an additional 2 million cycles using a modified ISO 14242 load waveform. In this context, a new approach was proposed in order to simulate, on a hip joint simulator, high-demand activities. In addition, the effects of these activities were analyzed in terms of wear and deformations of those polyethylenes by means of gravimetric method and micro X-ray computed tomography. In particular, while the gravimetric method was used for weight loss assessment, microcomputed tomography allowed for acquisition of additional quantitative information about the evolution of local wear and deformation through three-dimensional surface deviation maps for the entire cups’ surface. Experimental results showed that the wear and deformation behavior of these materials change according to different mechanical simulations. PMID:28772616
Reusable and disposable cups: An energy-based evaluation
NASA Astrophysics Data System (ADS)
Hocking, Martin B.
1994-11-01
A group of five different types of reusable and disposable hot drink cups have been analyzed in detail with respect to their overall energy costs during fabrication and use. Electricity generating methods and efficiencies have been found to be key factors in the primary energy consumption for the washing of reusable cups and a less important factor in cup fabrication. In Canada or the United States, over 500 or more use cycles, reusable cups are found to have about the same or slightly more energy consumption, use for use, as moulded polystyrene foam cups used once and then discarded. For the same area paper cups used once and discarded are found to consume less fossil fuel energy per use than any of the other cup types examined. Details of this analysis, which could facilitate the comparative assessment of other scenarios, are presented.
Clinical research evidence of cupping therapy in China: a systematic literature review.
Cao, Huijuan; Han, Mei; Li, Xun; Dong, Shangjuan; Shang, Yongmei; Wang, Qian; Xu, Shu; Liu, Jianping
2010-11-16
Though cupping therapy has been used in China for thousands of years, there has been no systematic summary of clinical research on it.This review is to evaluate the therapeutic effect of cupping therapy using evidence-based approach based on all available clinical studies. We included all clinical studies on cupping therapy for all kinds of diseases. We searched six electronic databases, all searches ended in December 2008. We extracted data on the type of cupping and type of diseases treated. 550 clinical studies were identified published between 1959 and 2008, including 73 randomized controlled trials (RCTs), 22 clinical controlled trials, 373 case series, and 82 case reports. Number of RCTs obviously increased during past decades, but the quality of the RCTs was generally poor according to the risk of bias of the Cochrane standard for important outcome within each trials. The diseases in which cupping was commonly employed included pain conditions, herpes zoster, cough or asthma, etc. Wet cupping was used in majority studies, followed by retained cupping, moving cupping, medicinal cupping, etc. 38 studies used combination of two types of cupping therapies. No serious adverse effects were reported in the studies. According to the above results, quality and quantity of RCTs on cupping therapy appears to be improved during the past 50 years in China, and majority of studies show potential benefit on pain conditions, herpes zoster and other diseases. However, further rigorous designed trials in relevant conditions are warranted to support their use in practice.
Cupping for Treating Pain: A Systematic Review
Kim, Jong-In; Lee, Myeong Soo; Lee, Dong-Hyo; Boddy, Kate; Ernst, Edzard
2011-01-01
The objective of this study was to assess the evidence for or against the effectiveness of cupping as a treatment option for pain. Fourteen databases were searched. Randomized clinical trials (RCTs) testing cupping in patients with pain of any origin were considered. Trials using cupping with or without drawing blood were included, while trials comparing cupping with other treatments of unproven efficacy were excluded. Trials with cupping as concomitant treatment together with other treatments of unproven efficacy were excluded. Trials were also excluded if pain was not a central symptom of the condition. The selection of studies, data extraction and validation were performed independently by three reviewers. Seven RCTs met all the inclusion criteria. Two RCTs suggested significant pain reduction for cupping in low back pain compared with usual care (P < .01) and analgesia (P < .001). Another two RCTs also showed positive effects of cupping in cancer pain (P < .05) and trigeminal neuralgia (P < .01) compared with anticancer drugs and analgesics, respectively. Two RCTs reported favorable effects of cupping on pain in brachialgia compared with usual care (P = .03) or heat pad (P < .001). The other RCT failed to show superior effects of cupping on pain in herpes zoster compared with anti-viral medication (P = .065). Currently there are few RCTs testing the effectiveness of cupping in the management of pain. Most of the existing trials are of poor quality. Therefore, more rigorous studies are required before the effectiveness of cupping for the treatment of pain can be determined. PMID:19423657
Yamamoto, Kengo; Masaoka, Toshinori; Manaka, Masakazu; Oonishi, Hironobu; Clarke, Ian; Shoji, Hiromu; Kawanabe, Keiichi; Imakiire, Atsuhiro
2004-04-01
We studied the micro-wear phenomena of unique, extensively cross-linked polyethylene cups (cross-linked with 1,000 kGy-irradiation) that had been used briefly in Japan. Two retrievals (at 15 years) came from the Japanese "SOM" hip system (implanted 1971-78). These were compared to a set of 0 kGy and 500-1,500 kGy cups run in our hip simulator. The polyethylene cups that had not been cross-linked had the greatest wear. The worn areas had a burnished appearance and were clearly separated from the unworn region by a distinct ridge-line. The worn areas had lost all machine tracks, showed a large amount of UHMWPE 'flow', and long PE fibrils. The associated surface rippling was degraded. These features were considered synonymous with severe polyethylene wear. In contrast, the worn areas in the very cross-linked cups had a visibly matte surface and no ridge-line. Micro-examination showed that the machine tracks were still present. Ripple formations were less obvious than in the cups that were not cross-linked, polyethylene surface fibrils were scarcer and all the fibrils were much smaller than in the cups that were not crosslinked. Our two retrieved cups and the simulator cups confirmed the greater wear-resistance of very cross-linked polyethylene. It should also be noted that the SOM cup design and processing were unique and differed greatly from that of modern polyethylene cups.
Schwabe, P; Märdian, S; Perka, C; Schaser, K-D
2016-04-01
Reconstruction/stable fixation of the acetabular columns to create an adequate periacetabular requirement for the implantation of a revision cup. Displaced/nondisplaced fractures with involvement of the posterior column. Resulting instability of the cup in an adequate bone stock situation. Periprosthetic acetabulum fractures with inadequate bone stock. Extended periacetabular defects with loss of anchorage options. Isolated periprosthetic fractures of the anterior column. Septic loosening. Dorsal approach. Dislocation of hip. Mechanical testing of inlaying acetabular cup. With unstable cup situation explantation of the cup, fracture fixation of acetabulum with dorsal double plate osteosynthesis along the posterior column. Cup revision. Hip joint reposition. Early mobilization; partial weight bearing for 12 weeks. Thrombosis prophylaxis. Clinical and radiological follow-ups. Periprosthetic acetabular fracture in 17 patients with 9 fractures after primary total hip replacement (THR), 8 after revision THR. Fractures: 12 due to trauma, 5 spontaneously; 7 anterior column fractures, 5 transverse fractures, 4 posterior column fractures, 1 two column fracture after hemiendoprosthesis. 5 type 1 fractures and 12 type 2 fractures. Operatively treated cases (10/17) received 3 reinforcement ring, 2 pedestal cup, 1 standard revision cup, cup-1 cage construct, 1 ventral plate osteosynthesis, 1 dorsal plate osteosynthesis, and 1 dorsal plate osteosynthesis plus cup revision (10-month Harris Hip Score 78 points). Radiological follow-up for 10 patients: consolidation of fractures without dislocation and a fixed acetabular cup. No revision surgeries during follow-up; 2 hip dislocations, 1 transient sciatic nerve palsy.
1987-10-01
include Security Classification) Instrumentation for scientific computing in neural networks, information science, artificial intelligence, and...instrumentation grant to purchase equipment for support of research in neural networks, information science, artificail intellignece , and applied mathematics...in Neural Networks, Information Science, Artificial Intelligence, and Applied Mathematics Contract AFOSR 86-0282 Principal Investigator: Stephen
IQARIS : a tool for the intelligent querying, analysis, and retrieval from information systems.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hummel, J. R.; Silver, R. B.
Information glut is one of the primary characteristics of the electronic age. Managing such large volumes of information (e.g., keeping track of the types, where they are, their relationships, who controls them, etc.) can be done efficiently with an intelligent, user-oriented information management system. The purpose of this paper is to describe a concept for managing information resources based on an intelligent information technology system developed by the Argonne National Laboratory for managing digital libraries. The Argonne system, Intelligent Query (IQ), enables users to query digital libraries and view the holdings that match the query from different perspectives.
ERIC Educational Resources Information Center
School Foodservice Journal, 1972
1972-01-01
Answers questions about the approach, tells the story of how the program works in the San Diego Mission School in New Mexico, and gives information on those companies in industry that manufacture products meeting USDA specifications. (Author)
System for tomographic determination of the power distribution in electron beams
Elmer, John W.; Teruya, Alan T.; O'Brien, Dennis W.
1995-01-01
A tomographic technique for measuring the current density distribution in electron beams using electron beam profile data acquired from a modified Faraday cup to create an image of the current density in high and low power beams. The modified Faraday cup includes a narrow slit and is rotated by a stepper motor and can be moved in the x, y and z directions. The beam is swept across the slit perpendicular thereto and controlled by deflection coils, and the slit rotated such that waveforms are taken every few degrees form 0.degree. to 360.degree. and the waveforms are recorded by a digitizing storage oscilloscope. Two-dimensional and three-dimensional images of the current density distribution in the beam can be reconstructed by computer tomography from this information, providing quantitative information about the beam focus and alignment.
System for tomographic determination of the power distribution in electron beams
Elmer, J.W.; Teruya, A.T.; O`Brien, D.W.
1995-11-21
A tomographic technique for measuring the current density distribution in electron beams using electron beam profile data acquired from a modified Faraday cup to create an image of the current density in high and low power beams. The modified Faraday cup includes a narrow slit and is rotated by a stepper motor and can be moved in the x, y and z directions. The beam is swept across the slit perpendicular thereto and controlled by deflection coils, and the slit rotated such that waveforms are taken every few degrees form 0{degree} to 360{degree} and the waveforms are recorded by a digitizing storage oscilloscope. Two-dimensional and three-dimensional images of the current density distribution in the beam can be reconstructed by computer tomography from this information, providing quantitative information about the beam focus and alignment. 12 figs.
Gudkina, Jekaterina; Brinkmane, Anda
2010-01-01
To assess possible relationship between caries experience, salivary cariogenic microflora and free sugar consumption in 6 year and 12 year old children in Riga, to evaluate these variables in risk assessment. 79 children aged 6 and 96 children aged 12 were examined clinically and by bitewing X-ray for caries diagnosis. Also all children or their parents were questioned about number of tea spoons containing sugar used per cup and frequency of cups used daily. Salivary mutans streptococci (MS) and lactobacilli (LB) (CRT-bacteria; Ivoclar; Vivadent; Liechtenstein) were determined only for children with dmft/DMFT>4: 27.8% at the age of 6, 40.6% at the age of 12. All data were statistically analyzed using frequency tables and analysis of variance. Statistical significance of differences in proportions was tested using chi-square test, Analysis included evaluation of how changes in variables such as free sugar consumption affects caries in particular age group. Mean number of tea spoons containing sugar used per cup was 1.47 in 6 year olds and 1.86 in 12 year olds, but daily amount of tea spoons containing sugar was 2.71 and 4.36 in each age group accordingly. Tea spoons of sugar per cup were associated with caries experience only in 6 year olds (p=0.098). A significant association was observed between caries experience, salivary MS and an amount of tea spoons containing sugar used per cup in both age groups (for 6 y.o. p= 0.037, for 12 y.o. p=0.037). Also caries experience was strongly associated with salivary MS and daily amount of tea spoons containing sugar, but only in 12 year olds (p=0.041). The information of free sugar consumption per cup or daily gives the possibility to control free sugar use in order to reduce caries development in 6 year old and 12 year old children in Riga.
NASA Technical Reports Server (NTRS)
2004-01-01
KENNEDY SPACE CENTER, FLA. Sitting in front of the open hatch into Discovery, which is in the Orbiter Processing Facility, Mike Bolt (left), NASAs Jack Legere (center front) and Jay Feaster (right) display the Stanley Cup. Feaster is general manager of the Tampa Bay Lightning, who won the cup in 2004, and Bolt is keeper of the cup. Legere is NASA Quality Assurance specialist for the Shuttle Program. The cup was also briefly available for viewing by employees in the KSC Training Auditorium. Feaster brought the cup to KSC while on a tour. The Stanley Cup weighs 35 pounds and is more than 100 years old. The Lightning will be added to the cup in September.
Mathematical Analysis of the Effect of Rotor Geometry on Cup Anemometer Response
Sanz-Andrés, Ángel; Sorribes-Palmer, Félix
2014-01-01
The calibration coefficients of two commercial anemometers equipped with different rotors were studied. The rotor cups had the same conical shape, while the size and distance to the rotation axis varied. The analysis was based on the 2-cup positions analytical model, derived using perturbation methods to include second-order effects such as pressure distribution along the rotating cups and friction. The comparison with the experimental data indicates a nonuniform distribution of aerodynamic forces on the rotating cups, with higher forces closer to the rotating axis. The 2-cup analytical model is proven to be accurate enough to study the effect of complex forces on cup anemometer performance. PMID:25110735
Hansen, Torben Baek; Stilling, Maiken
2013-02-01
Cup failure is a recognized problem in total trapeziometacarpal (TM) joint prostheses; it may be related to poor fixation, which can be revealed by radiostereometric analysis (RSA). We compared the early implant migration of cemented trapezium cups to that of uncemented screw cups. In a prospective, parallel-group, randomized patient-blinded clinical trial, we included 32 hands in 28 patients (5 males) with a mean age of 58 (40-77) years and with Eaton stage-2 or -3 osteoarthritis of the trapeziometacarpal joint. Patients were randomized to surgery with a cemented DLC all-polyethylene cup (C) (n = 16) or an uncemented hydroxyapatite-coated chrome-cobalt Elektra screw cup (UC) (n = 16). Uncemented cups were inserted without threading of the bone. Stereoradiographs for evaluation of cup migration (primary effect size) and DASH and pain scores were obtained during 2 years of follow-up. The 2-year total translation (TT) was similar (p = 0.2): 0.24 mm (SD 0.10) for the C (n = 11) and 0.19 mm (SD 0.16) for the UC (n = 11). Variances were similar (p = 0.4). Judged by RSA, 2 UC cups and 1 C cup became loose (TT > 1 mm). Both UC cups were found to be loose at revision. Grip strength, pain, and DASH scores were similar between groups at all measurement points. Early implant fixation and clinical outcome were equally good with both cup designs. This is the first clinical RSA study on trapezium cups, and the method appears to be clinically useful for detection of loose implants.
Multiple data sets and modelling choices in a comparative LCA of disposable beverage cups.
van der Harst, Eugenie; Potting, José; Kroeze, Carolien
2014-10-01
This study used multiple data sets and modelling choices in an environmental life cycle assessment (LCA) to compare typical disposable beverage cups made from polystyrene (PS), polylactic acid (PLA; bioplastic) and paper lined with bioplastic (biopaper). Incineration and recycling were considered as waste processing options, and for the PLA and biopaper cup also composting and anaerobic digestion. Multiple data sets and modelling choices were systematically used to calculate average results and the spread in results for each disposable cup in eleven impact categories. The LCA results of all combinations of data sets and modelling choices consistently identify three processes that dominate the environmental impact: (1) production of the cup's basic material (PS, PLA, biopaper), (2) cup manufacturing, and (3) waste processing. The large spread in results for impact categories strongly overlaps among the cups, however, and therefore does not allow a preference for one type of cup material. Comparison of the individual waste treatment options suggests some cautious preferences. The average waste treatment results indicate that recycling is the preferred option for PLA cups, followed by anaerobic digestion and incineration. Recycling is slightly preferred over incineration for the biopaper cups. There is no preferred waste treatment option for the PS cups. Taking into account the spread in waste treatment results for all cups, however, none of these preferences for waste processing options can be justified. The only exception is composting, which is least preferred for both PLA and biopaper cups. Our study illustrates that using multiple data sets and modelling choices can lead to considerable spread in LCA results. This makes comparing products more complex, but the outcomes more robust. Copyright © 2014 Elsevier B.V. All rights reserved.
Bone remodelling around HA-coated acetabular cups
Nielsen, P. T.; Søballe, K.
2006-01-01
This study was designed to investigate bone remodelling around the cup in cementless THA. Previous studies indicate an advantage of better sealing of the bone-prosthesis interface by HA/TCP coating of implants, inhibiting polyethylene-induced osteolysis. One hundred patients gave informed consent to participate in a controlled randomized study between porous coated Trilogy versus Trilogy Calcicoat (HA/TCP coated). The cup was inserted in press-fit fixation. The femoral component was a cementless porous coated titanium alloy stem (Bi-Metric), with a modular 28-mm CrCo head. The Harris Hip Score (HHS) and bone mineral density (BMD) determined by DEXA scanning were used to study the effect. Measurements revealed no difference between the two groups after 3 years either in the clinical outcome or in terms of periprosthetic bone density. Patients with a body mass index above normal regained more bone mineral than patients with normal weight. This finding supports the assumption that load is beneficial to bone remodelling. PMID:16761153
AISI/DOE Technology Roadmap Program: Cold Work Embrittlement of Interstitial Free Steel
DOE Office of Scientific and Technical Information (OSTI.GOV)
John T Bowker; Pierre Martin
2002-10-31
This work addresses the issues of measurement of secondary cold work embrittlement (SCWE) of an IF steel in deep-drawn parts using laboratory tests, and its correlation with real part fracture. It aimed at evaluating the influence of the steel chemistry and processing condition, microstructure, and test conditions, on SCWE as well as the effect of SCWE on fatigue properties. Size 6-in. cups produced with various draw ratios or trimmed at different heights were tested to determine the ductile-to-brittle-transition temperature (DBTT) as a function of strain. The 2-in. cup/expansion test, bend test and fracture of notched specimens were also used tomore » generate information complementary to that provided by the 6-inch cup/expansion test. The relationship between laboratory tests and fracture in real parts was established by testing large-scale parts. The fatigue behavior was investigated in the as-rolled and deep drawn (high stain) conditions, using prestrained specimens taken from the wall of a formed part.« less
Psychologically Informed Implementations of Sugary-Drink Portion Limits
John, Leslie K.; Donnelly, Grant E.; Roberto, Christina A.
2017-01-01
In 2012, the New York City Board of Health prohibited restaurants from selling sugary drinks in containers that would hold more than 16 oz. Although a state court ruled that the Board of Health did not have the authority to implement such a policy, it remains a legally viable option for governments and a voluntary option for restaurants. However, there is very limited empirical data on how such a policy might affect the purchasing and consumption of sugary drinks. We report four well-powered, incentive-compatible experiments in which we evaluated two possible ways that restaurants might comply with such a policy: bundling (i.e., dividing the contents of oversized cups into two regulation-size cups) and providing free refills (i.e., offering a regulation-size cup with unlimited refills). Bundling caused people to buy less soda. Free refills increased consumption, especially when a waiter served the refills. This perverse effect was reduced in self-service contexts that required walking just a few steps to get a refill. PMID:28362567
Estellano, Victor H; Pozo, Karla; Efstathiou, Christos; Pozo, Katerine; Corsolini, Simonetta; Focardi, Silvano
2015-10-01
Polyurethane foam disks (PUF) passive air samplers (PAS) were deployed over 4 sampling periods of 3-5-months (≥ 1 year) at ten urban and rural locations throughout the Tuscany Region. The purpose was to assess the occurrence and seasonal variations of ten current-use pesticides (CUPs). PUF disk extracts were analyzed using GC-MS. The organophosphates insecticides; chlorpyrifos (3-580 pg m(-3)) and chlorpyrifos-methyl (below detection limit - to 570 pg m(-3)) presented the highest levels in air, and showed seasonal fluctuation coinciding with the growing seasons. The relative proportion urban/(urban + rural) ranged from 0.4 to 0.7 showing no differences between urban and rural concentrations. Air back trajectories analysis showed air masses passing over agricultural fields and potentially enhancing the drift of pesticides into the urban sites. This study represents the first information regarding CUPs in the atmosphere of Tuscany region using PAS-PUF disk. Copyright © 2015 Elsevier Ltd. All rights reserved.
Zarrinabadi, Zarrin; Isfandyari-Moghaddam, Alireza; Erfani, Nasrolah; Tahour Soltani, Mohsen Ahmadi
2018-01-01
INTRODUCTION: According to the research mission of the librarianship and information sciences field, it is necessary to have the ability to communicate constructively between the user of the information and information in these students, and it appears more important in medical librarianship and information sciences because of the need for quick access to information for clinicians. Considering the role of spiritual intelligence in capability to establish effective and balanced communication makes it important to study this variable in librarianship and information students. One of the main factors that can affect the results of any research is conceptual model of measure variables. Accordingly, the purpose of this study was codification of spiritual intelligence measurement model. METHODS: This correlational study was conducted through structural equation model, and 270 students were opted from library and medical information students of nationwide medical universities by simple random sampling and responded to the King spiritual intelligence questionnaire (2008). Initially, based on the data, the model parameters were estimated using maximum likelihood method; then, spiritual intelligence measurement model was tested by fit indices. Data analysis was performed by Smart-Partial Least Squares software. RESULTS: Preliminary results showed that due to the positive indicators of predictive association and t-test results for spiritual intelligence parameters, the King measurement model has the acceptable fit and internal correlation of the questionnaire items was significant. Composite reliability and Cronbach's alpha of parameters indicated high reliability of spiritual intelligence model. CONCLUSIONS: The spiritual intelligence measurement model was evaluated, and results showed that the model has a good fit, so it is recommended that domestic researchers use this questionnaire to assess spiritual intelligence. PMID:29922688
Zarrinabadi, Zarrin; Isfandyari-Moghaddam, Alireza; Erfani, Nasrolah; Tahour Soltani, Mohsen Ahmadi
2018-01-01
According to the research mission of the librarianship and information sciences field, it is necessary to have the ability to communicate constructively between the user of the information and information in these students, and it appears more important in medical librarianship and information sciences because of the need for quick access to information for clinicians. Considering the role of spiritual intelligence in capability to establish effective and balanced communication makes it important to study this variable in librarianship and information students. One of the main factors that can affect the results of any research is conceptual model of measure variables. Accordingly, the purpose of this study was codification of spiritual intelligence measurement model. This correlational study was conducted through structural equation model, and 270 students were opted from library and medical information students of nationwide medical universities by simple random sampling and responded to the King spiritual intelligence questionnaire (2008). Initially, based on the data, the model parameters were estimated using maximum likelihood method; then, spiritual intelligence measurement model was tested by fit indices. Data analysis was performed by Smart-Partial Least Squares software. Preliminary results showed that due to the positive indicators of predictive association and t -test results for spiritual intelligence parameters, the King measurement model has the acceptable fit and internal correlation of the questionnaire items was significant. Composite reliability and Cronbach's alpha of parameters indicated high reliability of spiritual intelligence model. The spiritual intelligence measurement model was evaluated, and results showed that the model has a good fit, so it is recommended that domestic researchers use this questionnaire to assess spiritual intelligence.
Cupping in dermatology: a critical review and update.
Soliman, Yssra; Hamed, Nouran; Khachemoune, Amor
2018-06-01
Cupping is an ancient procedure that has been practiced for thousands of years. It has been used to treat a variety of medical conditions, including dermatological ones. Cupping has been described in the literature for the treatment of conditions such as acne and eczema. The procedure is fundamentally divided into dry cupping and wet cupping; however, there have been many modern adaptations. Adverse events related to the procedure have been reported in the literature and should be considered by patients. However, cupping has a promising role in helping manage dermatological conditions.
76 FR 77575 - Information Collection Requests Under OMB Review; Proposed Collection of Information
Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-13
... proposed information collection, Intelligence Background Questionnaire (OMB Control Number 0420--pending... employment any persons who have engaged in intelligence activity or related work or who have been employed by or connected with an intelligence Agency. It is crucial to the Peace Corps in carrying out its...
Schwarz, T; Weber, M; Wörner, M; Renkawitz, T; Grifka, J; Craiovan, B
2017-05-01
Accurate assessment of cup orientation on postoperative radiographs is essential for evaluating outcome after THA. However, accuracy is impeded by the deviation of the central X-ray beam in relation to the cup and the impossibility of measuring retroversion on standard pelvic radiographs. In an experimental trial, we built an artificial cup holder enabling the setting of different angles of anatomical anteversion and inclination. Twelve different cup orientations were investigated by three examiners. After comparing the two methods for radiographic measurement of the cup position developed by Lewinnek and Widmer, we showed how to differentiate between anteversion and retroversion in each cup position by using a second plane. To show the effect of the central beam offset on the cup, we X-rayed a defined cup position using a multidirectional central beam offset. According to Murray's definition of anteversion and inclination, we created a novel corrective procedure to balance measurement errors caused by deviation of the central beam. Measurement of the 12 different cup positions with the Lewinnek's method yielded a mean deviation of [Formula: see text] (95 % CI 1.3-2.3) from the original cup anteversion. The respective deviation with the Widmer/Liaw's method was [Formula: see text] (95 % CI 2.4-4.0). In each case, retroversion could be differentiated from anteversion with a second radiograph. Because of the multidirectional central beam offset ([Formula: see text] cm) from the acetabular cup in the cup holder ([Formula: see text] anteversion and [Formula: see text] inclination), the mean absolute difference for anteversion was [Formula: see text] (range [Formula: see text] to [Formula: see text] and [Formula: see text] (range [Formula: see text] to [Formula: see text] for inclination. The application of our novel mathematical correction of the central beam offset reduced deviation to a mean difference of [Formula: see text] for anteversion and [Formula: see text] for inclination. This novel calculation for central beam offset correction enables highly accurate measurement of the cup position.
The Role of Intelligence in Social Learning.
Vostroknutov, Alexander; Polonio, Luca; Coricelli, Giorgio
2018-05-02
Studies in cultural evolution have uncovered many types of social learning strategies that are adaptive in certain environments. The efficiency of these strategies also depends on the individual characteristics of both the observer and the demonstrator. We investigate the relationship between intelligence and the ways social and individual information is utilised to make decisions in an uncertain environment. We measure fluid intelligence and study experimentally how individuals learn from observing the choices of a demonstrator in a 2-armed bandit problem with changing probabilities of a reward. Participants observe a demonstrator with high or low fluid intelligence. In some treatments they are aware of the intelligence score of the demonstrator and in others they are not. Low fluid intelligence individuals imitate the demonstrator more when her fluid intelligence is known than when it is not. Conversely, individuals with high fluid intelligence adjust their use of social information, as the observed behaviour changes, independently of the knowledge of the intelligence of the demonstrator. We provide evidence that intelligence determines how social and individual information is integrated in order to make choices in a changing uncertain environment.
Press-fit acetabular cup fixation: principles and testing.
Macdonald, W; Carlsson, L V; Charnley, G J; Jacobsson, C M
1999-01-01
Pre-clinical testing of the fixation of press-fit acetabular components of total hip prostheses relies on cadaver or synthetic bone, but the properties and geometry of bone models differ from those of physiological bone. Cup designs use varied mechanisms for initial stability in bone; therefore, using different analogues and tests is appropriate. Press-fit cup stability was tested in the following: firstly, polyurethane (PU) foam modelling cancellous support; secondly, glass-fibre reinforced epoxide (GFRE) tubes modelling acetabular cortical support; thirdly, cadaveric acetabula. Three commercial cups [Harris-Galante II (H-G-II), Zimmer; Optifix, Smith & Nephew, Richards; porous coated anatomic (PCA), Howmedica] and an experimental cup with enhanced rim fixation were tested in three modes: direct pull-out, lever-out and axial torque. The fixation stabilities measured in the PU and the GFRE models showed trends consistent with those in cadaver bone, differing in the oversizing and cup geometry. The experimental cup was significantly more secure in most modes than other cups; the H-G II and Optifix cups showed similar stabilities, lower than that of the experimental cup but greater than that of the PCA cup (analysis of variance and Tukey's highly significant test; p < 0.001). The stabilities measured in cadaver bone more closely approximated those in GFRE. The use of several bone analogues enables separation of fixation mechanisms, allowing more accurate prediction of in vivo performance.
Otten, Volker T C; Crnalic, Sead; Röhrl, Stephan M; Nivbrant, Bo; Nilsson, Kjell G
2016-01-01
Screws, pegs and hydroxyapatite-coating are used to enhance the primary stability of uncemented cups. We present a 14-year follow-up of 48 hips randomized to four groups: press-fit only, press-fit plus screws, press-fit plus pegs and hydroxyapatite-coated cups. Radiostereometric migration measurements showed equally good stability regardless cup augmentation. The mean wear rate was high, 0.21 mm/year, with no differences between the groups. Seven hips had radiographical osteolysis but only in hips with augmented cups. Cups without screw-holes compared with cups with screw-holes resulted in better clinical outcome at the 14-year follow-up. Thus, augmentation of uncemented cups with screws, pegs, or hydroxyapatite did not appear to improve the long-term stability compared with press-fit only. Copyright © 2016 Elsevier Inc. All rights reserved.
Dispersal of seeds from splash-cup plants
NASA Astrophysics Data System (ADS)
Pepper, Rachel
2017-11-01
Splash cup plants disperse their seeds with the help of raindrops. The seeds sit in a small (mm-scale) conical cup and are ejected upon drop impact. The seeds are ejected at velocities up to five times the impact speed of the raindrop, and are dispersed up to 1 m away from the parent plant, which is only a few cm high. Previous work investigating the mechanism of this remarkable dispersal predicted an optimum cup opening angle of around 40°, which matched reasonably well with experiments performed with 3D-printed splash cup models. Those experiments were done with off-center drop impacts on initially empty cups with no seeds. We discuss similar experiments for cups that are not initially empty, but rather contain seed mimics, water, or both seeds and water. For some of these realistic initial states results are strikingly different from empty cups. Connections to theory will also be discussed.
Leal Neto, Onicio; Dimech, George Santiago; Libel, Marlo; de Souza, Wayner Vieira; Cesse, Eduarda; Smolinski, Mark; Oliveira, Wanderson; Albuquerque, Jones
2017-05-04
The 2005 International Health Regulations (IHRs) established parameters for event assessments and notifications that may constitute public health emergencies of international concern. These requirements and parameters opened up space for the use of nonofficial mechanisms (such as websites, blogs, and social networks) and technological improvements of communication that can streamline the detection, monitoring, and response to health problems, and thus reduce damage caused by these problems. Specifically, the revised IHR created space for participatory surveillance to function, in addition to the traditional surveillance mechanisms of detection, monitoring, and response. Participatory surveillance is based on crowdsourcing methods that collect information from society and then return the collective knowledge gained from that information back to society. The spread of digital social networks and wiki-style knowledge platforms has created a very favorable environment for this model of production and social control of information. The aim of this study was to describe the use of a participatory surveillance app, Healthy Cup, for the early detection of acute disease outbreaks during the Fédération Internationale de Football Association (FIFA) World Cup 2014. Our focus was on three specific syndromes (respiratory, diarrheal, and rash) related to six diseases that were considered important in a mass gathering context (influenza, measles, rubella, cholera, acute diarrhea, and dengue fever). From May 12 to July 13, 2014, users from anywhere in the world were able to download the Healthy Cup app and record their health condition, reporting whether they were good, very good, ill, or very ill. For users that reported being ill or very ill, a screen with a list of 10 symptoms was displayed. Participatory surveillance allows for the real-time identification of aggregates of symptoms that indicate possible cases of infectious diseases. From May 12 through July 13, 2014, there were 9434 downloads of the Healthy Cup app and 7155 (75.84%) registered users. Among the registered users, 4706 (4706/7155, 65.77%) were active users who posted a total of 47,879 times during the study period. The maximum number of users that signed up in one day occurred on May 30, 2014, the day that the app was officially launched by the Minister of Health during a press conference. During this event, the Minister of Health announced the special government program Health in the World Cup on national television media. On that date, 3633 logins were recorded, which accounted for more than half of all sign-ups across the entire duration of the study (50.78%, 3633/7155). Participatory surveillance through community engagement is an innovative way to conduct epidemiological surveillance. Compared to traditional epidemiological surveillance, advantages include lower costs of data acquisition, timeliness of information collected and shared, platform scalability, and capacity for integration between the population being served and public health services. ©Onicio Leal Neto, George Santiago Dimech, Marlo Libel, Wayner Vieira de Souza, Eduarda Cesse, Mark Smolinski, Wanderson Oliveira, Jones Albuquerque. Originally published in JMIR Public Health and Surveillance (http://publichealth.jmir.org), 04.05.2017.
ERIC Educational Resources Information Center
Harvey, Francis A.
This paper describes the evolution and development of an intelligent information system, i.e., a knowledge base for steel structures being undertaken as part of the Technical Information Center for Steel Structures at Lehigh University's Center of Advanced Technology for Large Structural Systems (ATLSS). The initial development of the Technical…
Clinical research evidence of cupping therapy in China: a systematic literature review
2010-01-01
Background Though cupping therapy has been used in China for thousands of years, there has been no systematic summary of clinical research on it. This review is to evaluate the therapeutic effect of cupping therapy using evidence-based approach based on all available clinical studies. Methods We included all clinical studies on cupping therapy for all kinds of diseases. We searched six electronic databases, all searches ended in December 2008. We extracted data on the type of cupping and type of diseases treated. Results 550 clinical studies were identified published between 1959 and 2008, including 73 randomized controlled trials (RCTs), 22 clinical controlled trials, 373 case series, and 82 case reports. Number of RCTs obviously increased during past decades, but the quality of the RCTs was generally poor according to the risk of bias of the Cochrane standard for important outcome within each trials. The diseases in which cupping was commonly employed included pain conditions, herpes zoster, cough or asthma, etc. Wet cupping was used in majority studies, followed by retained cupping, moving cupping, medicinal cupping, etc. 38 studies used combination of two types of cupping therapies. No serious adverse effects were reported in the studies. Conclusions According to the above results, quality and quantity of RCTs on cupping therapy appears to be improved during the past 50 years in China, and majority of studies show potential benefit on pain conditions, herpes zoster and other diseases. However, further rigorous designed trials in relevant conditions are warranted to support their use in practice. PMID:21078197
Snijders, Thom E; Willemsen, Koen; van Gaalen, Steven M; Castelein, Rene M; Weinans, Harrie; de Gast, Arthur
2018-05-01
Dislocation is one of the main reasons for revision of total hip arthroplasty but dislocation rates have not changed in the past decades, compromising patients' well-being. Acetabular cup orientation plays a key role in implant stability and has been widely studied. This article investigates whether there is a consensus on optimal cup orientation, which is necessary when using a navigation system. A systematic search of the literature in the PubMed, Embase and Cochrane databases was performed (March 2017) to identify articles that investigated the direct relationship between cup orientation and dislocation, including a thorough evaluation of postoperative cup orientation assessment methods. Twenty eight relevant articles evaluating a direct relation between dislocation and cup orientation could not come to a consensus. The key reason is a lack of uniformity in the assessment of cup orientation. Cup orientation is assessed with different imaging modalities, different methodologies, different definitions for inclination and anteversion, several reference planes and distinct patient positions. All available studies lack uniformity in cup orientation assessment; therefore it is impossible to reach consensus on optimal cup orientation. Using navigation systems for placement of the cup is inevitably flawed when using different definitions in the preoperative planning, peroperative placement and postoperative evaluation. Further methodological development is required to assess cup orientation. Consequently, the postoperative assessment should be uniform, thus differentiating between anterior and posterior dislocation, use the same definitions for inclination and anteversion with the same reference plane and with the patient in the same position.
Marofi, Maryam; Abedini, Fatemeh; Mohammadizadeh, Majid; Talakoub, Sedigheh
2016-01-01
Premature neonates' feeding is of great importance due to its effective role in their growth. These neonates should reach an independent oral nutrition stage before being discharged from the Neonatal Intensive care Unit. Therefore, the researcher decided to conduct a study on the effect of palady and cup feeding on premature neonates' weight gain and their reaching full oral feeding time interval. This is a clinical trial with a quantitative design conducted on 69 premature infants (gestational age between 29 and 32 weeks) who were assigned to cup (n = 34) and palady (n = 35) feeding groups through random allocation. The first feeding was administrated either by cup or palady method in each shift within seven sequential days (total of 21 cup and palady feedings). Then, the rest of feeding was administrated by gavage. Mean hospitalization time (cup = 39.01 and palady = 30.4; P < 0.001) and mean time interval to reach full oral feeding (cup = 33.7 and palady = 24.1; P < 0.001) were significantly lower in palady group compared to cup group. Mean weight changes of neonates 7 weeks after the intervention compared to those in the beginning of the intervention were significantly more in palady group compared to the cup group (cup = 146.7 and palady = 198.8; P < 0.001). The neonates in palady group reached full oral feeding earlier than those of cup group. Subjects' weight gain was also higher in palady group compared to the cup group. Premature neonates with over 30 weeks of gestational age and physiological stability can be fed by palady.
Derbyshire, Brian; Raut, Videshnandan V.
2013-01-01
Historically, wire markers were attached to cemented all-plastic acetabular cups to demarcate the periphery and to measure socket wear. The wire shape was either a semi-circle passing over the pole of the cup, or a circle around the cup equator. More recently, “double-D” shaped markers were introduced with a part-circular aspect passing over the pole and a semi-circular aspect parallel to the equatorial plane. This configuration enabled cup retroversion to be distinguished from anteversion. In this study, the accuracy of radiographic measurement of cup orientation and wear was assessed for cups with “double-D” and circular markers. Each cup was attached to a measurement jig which could vary the anteversion/retroversion and internal/external rotation of the cup. A metal femoral head was fixed within the socket and radiographic images were created for all combinations of cup orientation settings. The images were measured using software with automatic edge detection, and cup orientation and zero-wear accuracies were determined for each setting. The median error for cup version measurements was similar for both types of wire marker (0.2° double-D marker, −0.24° circular marker), but measurements of the circular marker were more repeatable. The median inclination errors were 2.05° (double-D marker) and 0.23° (circular marker). The median overall “zero wear” errors were 0.19 mm (double-D marker) and 0.03 mm (circular marker). Measurements of the circular wire marker were much more repeatable. PMID:23813165
2017-10-01
AU/ACSC/MORALES/AY17 AIR COMMAND AND STAFF COLLEGE DISTANCE LEARNING AIR UNIVERSITY DATA MAYHEM VERSUS NIMBLE INFORMATION : TRANSFORMING...HECTIC IMAGERY INTELLIGENCE DATA INTO ACTIONABLE INFORMATION USING ARTIFICIAL NEURAL NETWORKS by Luis A. Morales, Major, USAF A Research...finding solutions to compliment and supplement human analysts’ capacity, so intelligence and information can reach operators and end-users at the
Bressanello, Davide; Liberto, Erica; Cordero, Chiara; Rubiolo, Patrizia; Pellegrino, Gloria; Ruosi, Manuela R; Bicchi, Carlo
2017-01-01
This study is part of a wider project aiming to correlate the chemical composition of the coffee volatile fraction to its sensory properties with the end-goal of developing an instrumental analysis approach complementary to human sensory profiling. The proposed investigation strategy compares the chemical information concerning coffee aroma and flavor obtained with HS-SPME of the ground coffee and in-solution SBSE/SPME sampling combined with GC-MS to evaluate their compatibility with the cupping evaluation for quality control purposes. Roasted coffee samples with specific sensory properties were analyzed. The chemical results obtained by the three samplings were compared through multivariate analysis, and related to the samples' sensory attributes. Despite the differences between the three sampling approaches, data processing showed that the three methods provide the same kind of chemical information useful for sample discrimination, and that they could be used interchangeably to sample the coffee aroma and flavor. Copyright © 2016 Elsevier Ltd. All rights reserved.
Migration of the Duraloc cup after 5 years.
Stihsen, Christoph; Pabinger, Christof; Radl, Roman; Rehak, Peter; Windhager, Reinhard
2008-12-01
The Duraloc cup is a frequently used metal-backed, porous-coated, hemispherical, press-fit acetabular component. Published data on loosening rates are contradictory. In this study we investigated migration patterns with computer-assisted Einzel-Bild-Roentgen-Analyse (EBRA) of 67 Duraloc 100 cups. Cup migration and clinical scores were analysed over a 5-year follow-up period. Median total migration of the Duraloc 100 cup was 1.21 mm at 5 years. Seventy-five percent of implants were radiologically stable at 2 years and 90% at 4 years. One cup loosened aseptically at 60 months, requiring revision. Cup diameters > or = 54 mm migrated significantly more than cups < 54 mm in diameter (p = 0.029 at 4 years). There was a significant correlation between high polyethylene wear and further migrating cups within the first post-operative year (p = 0.035 at 12 months). Our analysis revealed significantly higher wear in males (p = 0.029 at 4 years). Radiological loosening at two years could be calculated using receiver-operating characteristic curve analysis, and 1.2 mm as an adequate threshold value (sensitivity = 100%, specificity = 89%).
A level set method for cupping artifact correction in cone-beam CT
DOE Office of Scientific and Technical Information (OSTI.GOV)
Xie, Shipeng; Li, Haibo; Ge, Qi
2015-08-15
Purpose: To reduce cupping artifacts and improve the contrast-to-noise ratio in cone-beam computed tomography (CBCT). Methods: A level set method is proposed to reduce cupping artifacts in the reconstructed image of CBCT. The authors derive a local intensity clustering property of the CBCT image and define a local clustering criterion function of the image intensities in a neighborhood of each point. This criterion function defines an energy in terms of the level set functions, which represent a segmentation result and the cupping artifacts. The cupping artifacts are estimated as a result of minimizing this energy. Results: The cupping artifacts inmore » CBCT are reduced by an average of 90%. The results indicate that the level set-based algorithm is practical and effective for reducing the cupping artifacts and preserving the quality of the reconstructed image. Conclusions: The proposed method focuses on the reconstructed image without requiring any additional physical equipment, is easily implemented, and provides cupping correction through a single-scan acquisition. The experimental results demonstrate that the proposed method successfully reduces the cupping artifacts.« less
Welding torch gas cup extension
NASA Technical Reports Server (NTRS)
Gordon, Stephen S. (Inventor)
1988-01-01
The invention relates to a gas shielded electric arc welding torch having a detachable gas cup extension which may be of any desired configuration or length. The gas cup extension assembly is mounted on a standard electric welding torch gas cup to enable welding in areas with limited access. The gas cup assembly has an upper tubular insert that fits within the gas cup such that its lower portion protrudes thereform and has a lower tubular extension that is screwed into the lower portion. The extension has a rim to define the outer perimeter of the seat edge about its entrance opening so a gasket may be placed to effect an airtight seal between the gas cup and extension. The tubular extension may be made of metal or cermaic material that can be machined. The novelty lies in the use of an extension assembly for a standard gas cup of an electric arc welding torch which extension assembly is detachable permitting the use of a number of extensions which may be of different configurations and materials and yet fit the standard gas cup.
Early loosening of a press-fit cup with ceramic-on-ceramic articulation: our early results.
Haverkamp, Daniël; Westerbos, Stijn; Campo, Martin M; Boonstra, Ritsert H; Rob Albers, G H; van der Vis, Harm M
2013-12-01
In this study, we present the short-term results of the Selexys TH+ cup with the Ceramys inlay which is a press-fit cup with a ceramic-on-ceramic articulation. (Mathys, Bettlach, Switzerland). We compared the results with a retrospective-matched control group with a Delta PF cup (Lima, Udine, Italy), which is also a press-fit cup with a ceramic-on-ceramic articulation. 257 elective hip arthroplasties with the Selexys TH+ cup in 250 patients placed in 2009 and 2010 were analyzed and compared with a control group retrospective analysis of the uncemented Delta PF cup (Lima, Udine, Italy) placed in 2007 and 2008 in 208 patients (222 hips). Surgical technique and surgeons were identical in both groups. During a follow-up period of 3-21 months, 19 aseptic loosenings (7.4 %) were found for the Selexys TH+ cup. The survival plotted by a Kaplan-Meier curve shows a 1-year survival of 87.4 %. The Lima Delta PF cup showed a 1-year survival of 99.5 %. Failure analysis showed no clear explanation for this early loosening. The Selexys TH+ cup combined with the Ceramys ceramic-on-ceramic inlay coupling show an unacceptable high early revision rate. Therefore, we advice against using this combination.
Lean blowout limits of a gas turbine combustor operated with aviation fuel and methane
NASA Astrophysics Data System (ADS)
Xiao, Wei; Huang, Yong
2016-05-01
Lean blowout (LBO) limits is critical to the operational performance of combustion systems in propulsion and power generation. The swirl cup plays an important role in flame stability and has been widely used in aviation engines. Therefore, the effects of swirl cup geometry and flow dynamics on LBO limits are significant. An experiment was conducted for studying the lean blowout limits of a single dome rectangular model combustor with swirl cups. Three types of swirl cup (dual-axial swirl cup, axial-radial swirl cup, dual-radial swirl cup) were employed in the experiment which was operated with aviation fuel (Jet A-1) and methane under the idle condition. Experimental results showed that, with using both Jet A-1 and methane, the LBO limits increase with the air flow of primary swirler for dual-radial swirl cup, while LBO limits decrease with the air flow of primary swirler for dual-axial swirl cup. In addition, LBO limits increase with the swirl intensity for three swirl cups. The experimental results also showed that the flow dynamics instead of atomization poses a significant influence on LBO limits. An improved semi-empirical correlation of experimental data was derived to predict the LBO limits for gas turbine combustors.
Intergovernmental Information Highways for Local Police Organizations: A Case Study
ERIC Educational Resources Information Center
Vidal, Denise Helena
2013-01-01
A lack of communication, information sharing, and a centralized and unified intelligence repository to gather, maintain, and analyze intelligence information before the September 11, 2001 (9/11) terrorist attacks limited the ability of U.S. law enforcement to share intelligence. The problem addressed in this case study was the lack of multiagency…
EIIS: An Educational Information Intelligent Search Engine Supported by Semantic Services
ERIC Educational Resources Information Center
Huang, Chang-Qin; Duan, Ru-Lin; Tang, Yong; Zhu, Zhi-Ting; Yan, Yong-Jian; Guo, Yu-Qing
2011-01-01
The semantic web brings a new opportunity for efficient information organization and search. To meet the special requirements of the educational field, this paper proposes an intelligent search engine enabled by educational semantic support service, where three kinds of searches are integrated into Educational Information Intelligent Search (EIIS)…
Pulsatile dry cupping in chronic low back pain - a randomized three-armed controlled clinical trial.
Teut, M; Ullmann, A; Ortiz, M; Rotter, G; Binting, S; Cree, M; Lotz, F; Roll, S; Brinkhaus, B
2018-04-02
We aimed to investigate the effectiveness of two different forms of dry pulsatile cupping in patients with chronic low back pain (cLBP) compared to medication on demand only in a three-armed randomized trial. 110 cLBP patients were randomized to regular pulsatile cupping with 8 treatments plus paracetamol on demand (n = 37), minimal cupping with 8 treatments plus paracetamol on demand (n = 36) or the control group with paracetamol on demand only (n = 37). Primary outcome was the pain intensity on a visual analogue scale (VAS, 0-100 mm) after 4 weeks, secondary outcome parameter included VAS pain intensity after 12 weeks, back function as measured with the 'Funktionsfragebogen Hannover Rücken' (FFbH-R) and health related quality of life questionnaire Short form 36 (SF-36) after 4 and 12 weeks. The mean baseline-adjusted VAS after 4 weeks was 34.9 mm (95% CI: 28.7; 41.2) for pulsatile cupping, 40.4 (34.2; 46.7) for minimal cupping and 56.1 (49.8; 62.4) for control group, resulting in statistically significant differences between pulsatile cupping vs. control (21.2 (12.2; 30.1); p < 0.001) and minimal cupping vs. control (15.7 (6.9; 24.4); p = 0.001). After 12 weeks, mean adjusted VAS difference between pulsatile cupping vs. control was 15.1 ((3.1; 27.1); p = 0.014), and between minimal cupping vs. control 11.5 ((- 0.44; 23.4); p = 0.059). Differences of VAS between pulsatile cupping and minimal cupping showed no significant differences after 4 or 12 weeks. Pulsatile cupping was also better (- 5.8 (- 11.5;-0.1); p = 0.045) compared to control for back function after 4 weeks, but not after 12 weeks (- 5.4 (- 11.7;0.8); p = 0.088), pulsatile cupping also showed better improvements on SF-36 physical component scale compared to control at 4 and 12 weeks (- 5.6 (- 9.3;-2.0); p = 0.003; - 6.1 (- 9.9;-2.4); p = 0.002). For back function and quality of life minimal cupping group was not statistically different to control after 4 and 12 weeks. Paracetamol intake did not differ between the groups (cupping vs. control (7.3 (- 0.4;15.0); p = 0.063); minimal cupping vs. control (6.3 (- 2.0;14.5); p = 0.133). Both forms of cupping were effective in cLBP without showing significant differences in direct comparison after four weeks, only pulsatile cupping showed effects compared to control after 12 weeks. The study was registered at ClinicalTrials.gov (identifier: NCT02090686 ).
2014-05-22
attempted to respond to the advances in technology and the growing power of geographical information system (GIS) tools. However, the doctrine...Geospatial intelligence (GEOINT), Geographical information systems (GIS) tools, Humanitarian Assistance/Disaster Relief (HA/DR), 2010 Haiti Earthquake...Humanitarian Assistance/Disaster Relief (HA/DR) Decisions Through Geospatial Intelligence (GEOINT) and Geographical Information Systems (GIS) Tools
Wet-cupping removes oxidants and decreases oxidative stress.
Tagil, Suleyman Murat; Celik, Huseyin Tugrul; Ciftci, Sefa; Kazanci, Fatmanur Hacievliyagil; Arslan, Muzeyyen; Erdamar, Nazan; Kesik, Yunus; Erdamar, Husamettin; Dane, Senol
2014-12-01
Wet-cupping therapy is one of the oldest known medical techniques. Although it is widely used in various conditions such as acute\\chronic inflammation, infectious diseases, and immune system disorders, its mechanism of action is not fully known. In this study, we investigated the oxidative status as the first step to elucidate possible mechanisms of action of wet cupping. Wet cupping therapy is implemented to 31 healthy volunteers. Venous blood samples and Wet cupping blood samples were taken concurrently. Serum nitricoxide, malondialdehyde levels and activity of superoxide dismutase and myeloperoxidase were measured spectrophotometrically. Wet cupping blood had higher activity of myeloperoxidase, lower activity of superoxide dismutase, higher levels of malondialdehyde and nitricoxide compared to the venous blood. Wet cupping removes oxidants and decreases oxidative stress. Copyright © 2014 Elsevier Ltd. All rights reserved.
Goebel, Paul; Kluess, Daniel; Wieding, Jan; Souffrant, Robert; Heyer, Horst; Sander, Manuela; Bader, Rainer
2013-03-01
To increase the range of motion of total hip endoprostheses, prosthetic heads need to be enlarged, which implies that the cup and/or liner thickness must decrease. This may have negative effects on the wear rate, because the acetabular cups and liners could deform during press-fit implantation and hip joint loading. We compared the metal cup and polyethylene liner deformations that occurred when different wall thicknesses were used in order to evaluate the resulting changes in the clearance of the articulating region. A parametric finite element model utilized three cup and liner wall thicknesses to analyze cup and liner deformations after press-fit implantation into the pelvic bone. The resultant hip joint force during heel strike was applied while the femur was fixed, accounting for physiological muscle forces. The deformation behavior of the liner under joint loading was therefore assessed as a function of the head diameter and the resulting clearance. Press-fit implantation showed diametral cup deformations of 0.096, 0.034, and 0.014 mm for cup wall thicknesses of 3, 5, and 7 mm, respectively. The largest deformations (average 0.084 ± 0.003 mm) of liners with thicknesses of 4, 6, and 8 mm occurred with the smallest cup wall thickness (3 mm). The smallest liner deformation (0.011 mm) was obtained with largest cup and liner wall thicknesses. Under joint loading, liner deformations in thin-walled acetabular cups (3 mm) reduced the initial clearance by about 50 %. Acetabular press-fit cups with wall thicknesses of ≤5 mm should only be used in combination with polyethylene liners >6 mm thick in order to minimize the reduction in clearance.
Radiographic cup anteversion measurement corrected from pelvic tilt.
Wang, Liao; Thoreson, Andrew R; Trousdale, Robert T; Morrey, Bernard F; Dai, Kerong; An, Kai-Nan
2017-11-01
The purpose of this study was to develop a novel technique to improve the accuracy of radiographic cup anteversion measurement by correcting the influence of pelvic tilt. Ninety virtual total hip arthroplasties were simulated from computed tomography data of 6 patients with 15 predetermined cup orientations. For each simulated implantation, anteroposterior (AP) virtual pelvic radiographs were generated for 11 predetermined pelvic tilts. A linear regression model was created to capture the relationship between radiographic cup anteversion angle error measured on AP pelvic radiographs and pelvic tilt. Overall, nine hundred and ninety virtual AP pelvic radiographs were measured, and 90 linear regression models were created. Pearson's correlation analyses confirmed a strong correlation between the errors of conventional radiographic cup anteversion angle measured on AP pelvic radiographs and the magnitude of pelvic tilt (P < 0.001). The mean of 90 slopes and y-intercepts of the regression lines were -0.8 and -2.5°, which were applied as the general correction parameters for the proposed tool to correct conventional cup anteversion angle from the influence of pelvic tilt. The current method proposes to measure the pelvic tilt on a lateral radiograph, and to use it as a correction for the radiographic cup anteversion measurement on an AP pelvic radiograph. Thus, both AP and lateral pelvic radiographs are required for the measurement of pelvic posture-integrated cup anteversion. Compared with conventional radiographic cup anteversion, the errors of pelvic posture-integrated radiographic cup anteversion were reduced from 10.03 (SD = 5.13) degrees to 2.53 (SD = 1.33) degrees. Pelvic posture-integrated cup anteversion measurement improves the accuracy of radiographic cup anteversion measurement, which shows the potential of further clarifying the etiology of postoperative instability based on planar radiographs. Copyright © 2017 IPEM. Published by Elsevier Ltd. All rights reserved.
28 CFR 23.20 - Operating principles.
Code of Federal Regulations, 2012 CFR
2012-07-01
... Judicial Administration DEPARTMENT OF JUSTICE CRIMINAL INTELLIGENCE SYSTEMS OPERATING POLICIES § 23.20 Operating principles. (a) A project shall collect and maintain criminal intelligence information concerning... shall not collect or maintain criminal intelligence information about the political, religious or social...
28 CFR 23.20 - Operating principles.
Code of Federal Regulations, 2014 CFR
2014-07-01
... Judicial Administration DEPARTMENT OF JUSTICE CRIMINAL INTELLIGENCE SYSTEMS OPERATING POLICIES § 23.20 Operating principles. (a) A project shall collect and maintain criminal intelligence information concerning... shall not collect or maintain criminal intelligence information about the political, religious or social...
28 CFR 23.20 - Operating principles.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Judicial Administration DEPARTMENT OF JUSTICE CRIMINAL INTELLIGENCE SYSTEMS OPERATING POLICIES § 23.20 Operating principles. (a) A project shall collect and maintain criminal intelligence information concerning... shall not collect or maintain criminal intelligence information about the political, religious or social...
28 CFR 23.20 - Operating principles.
Code of Federal Regulations, 2013 CFR
2013-07-01
... Judicial Administration DEPARTMENT OF JUSTICE CRIMINAL INTELLIGENCE SYSTEMS OPERATING POLICIES § 23.20 Operating principles. (a) A project shall collect and maintain criminal intelligence information concerning... shall not collect or maintain criminal intelligence information about the political, religious or social...
28 CFR 23.20 - Operating principles.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Judicial Administration DEPARTMENT OF JUSTICE CRIMINAL INTELLIGENCE SYSTEMS OPERATING POLICIES § 23.20 Operating principles. (a) A project shall collect and maintain criminal intelligence information concerning... shall not collect or maintain criminal intelligence information about the political, religious or social...
Intelligent Information Systems.
ERIC Educational Resources Information Center
Zabezhailo, M. I.; Finn, V. K.
1996-01-01
An Intelligent Information System (IIS) uses data warehouse technology to facilitate the cycle of data and knowledge processing, including input, standardization, storage, representation, retrieval, calculation, and delivery. This article provides an overview of IIS products and artificial intelligence systems, illustrates examples of IIS…
Hua, Xijin; Li, Junyan; Wang, Ling; Wilcox, Ruth; Fisher, John; Jin, Zhongmin
2015-10-01
One important loosening mechanism of the cemented total hip arthroplasty is the mechanical overload at the bone-cement interface and consequent failure of the cement fixation. Clinical studies have revealed that the outer diameter of the acetabular component is a key factor in influencing aseptic loosening of the hip arthroplasty. The aim of the present study was to investigate the influence of the cup outer diameter on the contact mechanics and cement fixation of a cemented total hip replacement (THR) with different wear penetration depths and under different cup inclination angles using finite element (FE) method. A three-dimensional FE model was developed based on a typical Charnley hip prosthesis. Two acetabular cup designs with outer diameters of 40 and 43 mm were modelled and the effect of cup outer diameter, penetration depth and cup inclination angle on the contact mechanics and cement fixation stresses in the cemented THR were studied. The results showed that for all penetration depths and cup inclination angles considered, the contact mechanics in terms of peak von Mises stress in the acetabular cup and peak contact pressure at the bearing surface for the two cup designs were similar (within 5%). However, the peak von Mises stress, the peak maximum principal stress and peak shear stress in the cement mantle at the bone-cement interface for the 43 mm diameter cup design were predicted to be lower compared to those for the 40 mm diameter cup design. The differences were predicted to be 15-19%, 15-22% and 18-20% respectively for different cup penetration depths and inclination angles, which compares to the clinical difference of aseptic loosening incidence of about 20% between the two cup designs. Copyright © 2015 IPEM. Published by Elsevier Ltd. All rights reserved.
Elgin, Ufuk; Cankaya, Bülent; Simsek, Tulay; Batman, Aygen
2010-01-01
To compare the optic disc topography parameters of children with juvenile diabetes mellitus and normal children using the Heidelberg Retinal Tomograph (HRT III) (Heidelberg Engineering, Heidelberg, Germany). The topographic optic disc parameters (cup volume, cup area, rim volume, rim area, disc area, mean cup-to-disc ratio, and mean cup depth) of 28 non-glaucomatous eyes of 28 children with type 1 diabetes mellitus and 28 eyes of 28 age-matched healthy children were compared using the nonparametric Mann-Whitney U test. No statistically significant differences were found between cup volume (P = .782), cup area (P = .878), rim volume (P = .853), disc area (P = .452), mean cup-to-disc ratio (P = .852), and mean cup depth (P = .711) of eyes of cases with diabetes mellitus and normal subjects. This result suggests that non-glaucomatous eyes of children with type 1 diabetes mellitus and healthy subjects have similar topographic optic disc characteristics. Copyright 2010, SLACK Incorporated.
Model architecture of intelligent data mining oriented urban transportation information
NASA Astrophysics Data System (ADS)
Yang, Bogang; Tao, Yingchun; Sui, Jianbo; Zhang, Feizhou
2007-06-01
Aiming at solving practical problems in urban traffic, the paper presents model architecture of intelligent data mining from hierarchical view. With artificial intelligent technologies used in the framework, the intelligent data mining technology improves, which is more suitable for the change of real-time road condition. It also provides efficient technology support for the urban transport information distribution, transmission and display.
NASA Astrophysics Data System (ADS)
Chen, Lei; Li, Dehua; Yang, Jie
2007-12-01
Constructing virtual international strategy environment needs many kinds of information, such as economy, politic, military, diploma, culture, science, etc. So it is very important to build an information auto-extract, classification, recombination and analysis management system with high efficiency as the foundation and component of military strategy hall. This paper firstly use improved Boost algorithm to classify obtained initial information, then use a strategy intelligence extract algorithm to extract strategy intelligence from initial information to help strategist to analysis information.
Sculco, Peter K; Ledford, Cameron K; Hanssen, Arlen D; Abdel, Matthew P; Lewallen, David G
2017-07-05
Complex acetabular reconstruction for major bone loss can require advanced methods such as the use of a cup-cage construct. The purpose of this study was to review outcomes after the initial development of the cup-cage technique and the subsequent evolution to the use of a half cup-cage construct. We performed a retrospective, single-center review of 57 patients treated with cup-cage reconstruction for major acetabular bone loss. All patients had major acetabular defects graded as Paprosky Type 2B through 3B, with 34 (60%) having an associated pelvic discontinuity. Thirty patients received a full cup-cage construct and 27, a half cup-cage construct. The mean follow-up was 5 years. Both the full and half cup-cage cohorts demonstrated significantly improved Harris hip score (HHS) values, from 36 to 72 at a minimum of 2 years of follow-up (p < 0.05). Early construct migration occurred in 4 patients, with stabilization prior to 2-year follow-up in all but 1 patient. Incomplete, zone-3, nonprogressive acetabular radiolucencies were observed in 2 (7%) of the full cup-cage constructs and 6 (22%) of the half cup-cage constructs. One patient with a full cup-cage construct underwent re-revision of the acetabular component for progressive migration and aseptic loosening. Short-term survivorship free from re-revision for any cause or reoperation was 89% (83% and 96% for full and half cup-cage cohorts, respectively). Both full and half cup-cage constructs demonstrated successful clinical outcomes and survivorship in the treatment of major acetabular defects and pelvic discontinuity. Each method is utilized on the basis of individual intraoperative findings, including the extent and pattern of bone loss, the quality and location of host bone remaining after preparation, and the presence of pelvic discontinuity. Longer-term follow-up is required to understand the durability of these constructs in treating major acetabular defects and pelvic discontinuity. Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.
System for tomographic determination of the power distribution in electron beams
Elmer, J.W.; Teruya, A.T.; O'Brien, D.W.
1995-01-17
A tomographic technique is disclosed for measuring the current density distribution in electron beams using electron beam profile data acquired from a modified Faraday cup to create an image of the current density in high and low power beams. The modified Faraday cup includes a narrow slit and is rotated by a stepper motor and can be moved in the x, y and z directions. The beam is swept across the slit perpendicular thereto and controlled by deflection coils, and the slit rotated such that waveforms are taken every few degrees form 0[degree] to 360[degree] and the waveforms are recorded by a digitizing storage oscilloscope. Two-dimensional and three-dimensional images of the current density distribution in the beam can be reconstructed by computer tomography from this information, providing quantitative information about the beam focus and alignment. 12 figures.
A confirmed case of toxic shock syndrome associated with the use of a menstrual cup
Mitchell, Michael A; Bisch, Steve; Arntfield, Shannon; Hosseini-Moghaddam, Seyed M
2015-01-01
Menstrual cups have been reported to be an acceptable substitute for tampons. These flexible cups have also been reported to provide a sustainable solution to menstrual management, with modest cost savings and no significant health risk. The present article documents the first case of toxic shock syndrome associated with the use of a menstrual cup in a woman 37 years of age, using a menstrual cup for the first time. Toxic shock syndrome and the literature on menstrual cups is reviewed and a possible mechanism for the development of toxic shock syndrome in the patient is described. PMID:26361491
A confirmed case of toxic shock syndrome associated with the use of a menstrual cup.
Mitchell, Michael A; Bisch, Steve; Arntfield, Shannon; Hosseini-Moghaddam, Seyed M
2015-01-01
Menstrual cups have been reported to be an acceptable substitute for tampons. These flexible cups have also been reported to provide a sustainable solution to menstrual management, with modest cost savings and no significant health risk. The present article documents the first case of toxic shock syndrome associated with the use of a menstrual cup in a woman 37 years of age, using a menstrual cup for the first time. Toxic shock syndrome and the literature on menstrual cups is reviewed and a possible mechanism for the development of toxic shock syndrome in the patient is described.
Le Cann, Sophie; Galland, Alexandre; Rosa, Benoît; Le Corroller, Thomas; Pithioux, Martine; Argenson, Jean-Noël; Chabrand, Patrick; Parratte, Sébastien
2014-09-01
Most acetabular cups implanted today are press-fit impacted cementless. Anchorage begins with the primary stability given by insertion of a slightly oversized cup. This primary stability is key to obtaining bone ingrowth and secondary stability. We tested the hypothesis that primary stability of the cup is related to surface roughness of the implant, using both an experimental and a numerical models to analyze how three levels of surface roughness (micro, macro and combined) affect the primary stability of the cup. We also investigated the effect of differences in diameter between the cup and its substrate, and of insertion force, on the cups' primary stability. The results of our study show that primary stability depends on the surface roughness of the cup. The presence of macro-roughness on the peripheral ring is found to decrease primary stability; there was excessive abrasion of the substrate, damaging it and leading to poor primary stability. Numerical modeling indicates that oversizing the cup compared to its substrate has an impact on primary stability, as has insertion force. Copyright © 2014 IPEM. Published by Elsevier Ltd. All rights reserved.
Migration of the Duraloc cup after 5 years
Stihsen, Christoph; Pabinger, Christof; Radl, Roman; Rehak, Peter
2007-01-01
The Duraloc cup is a frequently used metal-backed, porous-coated, hemispherical, press-fit acetabular component. Published data on loosening rates are contradictory. In this study we investigated migration patterns with computer-assisted Einzel-Bild-Roentgen-Analyse (EBRA) of 67 Duraloc 100 cups. Cup migration and clinical scores were analysed over a 5-year follow-up period. Median total migration of the Duraloc 100 cup was 1.21 mm at 5 years. Seventy-five percent of implants were radiologically stable at 2 years and 90% at 4 years. One cup loosened aseptically at 60 months, requiring revision. Cup diameters ≥54 mm migrated significantly more than cups <54 mm in diameter (p = 0.029 at 4 years). There was a significant correlation between high polyethylene wear and further migrating cups within the first post-operative year (p = 0.035 at 12 months). Our analysis revealed significantly higher wear in males (p = 0.029 at 4 years). Radiological loosening at two years could be calculated using receiver-operating characteristic curve analysis, and 1.2 mm as an adequate threshold value (sensitivity = 100%, specificity = 89%). PMID:17609953
Rijavec, B; Košak, R; Daniel, M; Kralj-Iglič, V; Dolinar, D
2015-01-01
In order to increase the lifetime of the total hip endoprosthesis, it is necessary to understand mechanisms leading to its failure. In this work, we address volumetric wear of the artificial cup, in particular the effect of its inclination with respect to the vertical. Volumetric wear was calculated by using mathematical models for resultant hip force, contact stress and penetration of the prosthesis head into the cup. Relevance of the dependence of volumetric wear on inclination of the cup (its abduction angle ϑA) was assessed by the results of 95 hips with implanted endoprosthesis. Geometrical parameters obtained from standard antero-posterior radiographs were taken as input data. Volumetric wear decreases with increasing cup abduction angle ϑA. The correlation within the population of 95 hips was statistically significant (P = 0.006). Large cup abduction angle minimises predicted volumetric wear but may increase the risk for dislocation of the artificial head from the cup in the one-legged stance. Cup abduction angle and direction of the resultant hip force may compensate each other to achieve optimal position of the cup with respect to wear and dislocation in the one-legged stance for a particular patient.
Collective Intelligence Generation from User Contributed Content
NASA Astrophysics Data System (ADS)
Solachidis, Vassilios; Mylonas, Phivos; Geyer-Schulz, Andreas; Hoser, Bettina; Chapman, Sam; Ciravegna, Fabio; Lanfranchi, Vita; Scherp, Ansgar; Staab, Steffen; Contopoulos, Costis; Gkika, Ioanna; Bakaimis, Byron; Smrz, Pavel; Kompatsiaris, Yiannis; Avrithis, Yannis
In this paper we provide a foundation for a new generation of services and tools. We define new ways of capturing, sharing and reusing information and intelligence provided by single users and communities, as well as organizations by enabling the extraction, generation, interpretation and management of Collective Intelligence from user generated digital multimedia content. Different layers of intelligence are generated, which together constitute the notion of Collective Intelligence. The automatic generation of Collective Intelligence constitutes a departure from traditional methods for information sharing, since information from both the multimedia content and social aspects will be merged, while at the same time the social dynamics will be taken into account. In the context of this work, we present two case studies: an Emergency Response and a Consumers Social Group case study.
78 FR 962 - Agency Information Collection Activities
Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-07
... OFFICE OF THE DIRECTOR OF NATIONAL INTELLIGENCE Agency Information Collection Activities AGENCY: Office of the Director of National Intelligence (ODNI). ACTION: Notice. SUMMARY: In December 2011, the... responsibilities assigned to the Director of National Intelligence (DNI) as Security Executive Agent. Accordingly...
21 CFR 872.6290 - Prophylaxis cup.
Code of Federal Regulations, 2014 CFR
2014-04-01
... DEVICES DENTAL DEVICES Miscellaneous Devices § 872.6290 Prophylaxis cup. (a) Identification. A prophylaxis cup is a device made of rubber intended to be held by a dental handpiece and used to apply polishing agents during prophylaxis (cleaning). The dental handpiece spins the rubber cup holding the polishing...
21 CFR 872.6290 - Prophylaxis cup.
Code of Federal Regulations, 2013 CFR
2013-04-01
... DEVICES DENTAL DEVICES Miscellaneous Devices § 872.6290 Prophylaxis cup. (a) Identification. A prophylaxis cup is a device made of rubber intended to be held by a dental handpiece and used to apply polishing agents during prophylaxis (cleaning). The dental handpiece spins the rubber cup holding the polishing...
21 CFR 872.6290 - Prophylaxis cup.
Code of Federal Regulations, 2012 CFR
2012-04-01
... DEVICES DENTAL DEVICES Miscellaneous Devices § 872.6290 Prophylaxis cup. (a) Identification. A prophylaxis cup is a device made of rubber intended to be held by a dental handpiece and used to apply polishing agents during prophylaxis (cleaning). The dental handpiece spins the rubber cup holding the polishing...
Cup Stacking: Does It Deserve a Place in Physical Education Curricula?
ERIC Educational Resources Information Center
Udermann, Brian E.; Murray, Steven R.
2006-01-01
Cup stacking has become commonplace in today's physical education nomenclature. Proponents make claims that cup stacking improves cognitive, affective, and psychomotor abilities. At physical education conferences, scores of professional physical educators eagerly watch cup stacking representatives construct and deconstruct a variety of pyramids…
A tale of Persian cupping therapy: 1001 potential applications and avenues for research.
Bamfarahnak, Hossein; Azizi, Amir; Noorafshan, Ali; Mohagheghzadeh, Abdolali
2014-01-01
Cupping therapy (CT) is one of the oldest medical techniques available, and is still used in several cultures instead of or as an adjunct or complement to 'western academic' medicine. Moreover, CT (wet or dry) is claimed to have therapeutic effects in many types of disorders which do not fully respond to conventional medicine or for which no effective treatment is available. However, no recent reviews of the clinical practice of cupping are available to the best of our knowledge. We describe the applications of CT as used in Traditional Iranian Medicine (TIM). Several databases were searched for relevant literature. In addition, we studied the main traditional treatises on TIM regarding the history and practice of CT. Information about current practices was obtained from a systematic survey among practitioners. Our results suggest that CT is currently prescribed for up to 120 diseases and disorders that are difficult to treat, including cutaneous (21.7%), musculoskeletal (15%), and central nervous system (13.3%) disorders. Moreover, TIM treatises note 25 specific sites on the body surface which correspond to certain diseases, and on which wet-cupping therapy has therapeutic effects. Additional clinical studies of CT may lead to findings on new therapeutic methods and may shed light on mechanisms of disease and illness that are not fully understood in conventional medicine. © 2014 S. Karger GmbH, Freiburg.
NASA Technical Reports Server (NTRS)
2004-01-01
KENNEDY SPACE CENTER, FLA. In the Orbiter Processing Facility, Jay Feaster, general manager of the National Hockey League 2004 Champions Tampa Bay Lightning, displays the Stanley Cup. At right is KSC Deputy Director Woodrow Whitlow. The cup was also briefly available for viewing by employees in the KSC Training Auditorium. Feaster brought the cup to KSC while on a tour. The Stanley Cup weighs 35 pounds and is more than 100 years old. The Lightning will be added to the cup in September.
Exploring volumetrically indexed cups
NASA Astrophysics Data System (ADS)
Jones, Dustin L.
2011-03-01
This article was inspired by a set of 12 cylindrical cups, which are volumetrically indexed; that is to say, the volume of cup n is equal to n times the volume of cup 1. Various sets of volumetrically indexed cylindrical cups are explored. I demonstrate how this children's toy is ripe for mathematical investigation, with connections to geometry, algebra and differential calculus. Students with an understanding of these topics should be able to complete the analysis and related exercises contained herein.
Sample rotating turntable kit for infrared spectrometers
Eckels, Joel Del [Livermore, CA; Klunder, Gregory L [Oakland, CA
2008-03-04
An infrared spectrometer sample rotating turntable kit has a rotatable sample cup containing the sample. The infrared spectrometer has an infrared spectrometer probe for analyzing the sample and the rotatable sample cup is adapted to receive the infrared spectrometer probe. A reflectance standard is located in the rotatable sample cup. A sleeve is positioned proximate the sample cup and adapted to receive the probe. A rotator rotates the rotatable sample cup. A battery is connected to the rotator.
Lauche, Romy; Spitzer, Julia; Schwahn, Barbara; Ostermann, Thomas; Bernardy, Kathrin; Cramer, Holger; Dobos, Gustav; Langhorst, Jost
2016-01-01
This study aimed to test the efficacy of cupping therapy to improve symptoms and quality of life in patients diagnosed with the fibromyalgia syndrome. Participants were randomly assigned to cupping therapy, sham or usual care. Cupping was administered five times at twice weekly intervals on the upper and lower back. The primary outcome measure was pain intensity at day 18. Secondary outcomes included functional disability, quality of life, fatigue and sleep quality as well as pressure pain sensitivity, satisfaction and safety at day 18 and 6 months. Altogether 141 patients were included in this study (139 females, 55.8 ± 9.1 years). After 18 days patients reported significant less pain after cupping compared to usual care (difference −12.4; 95% CI: −18.9; −5.9, p < 0.001) but not compared to sham (difference −3.0; 95% CI: −9.9, 3.9, p = 0.396). Further effects were found for quality of life compared to usual care. Patients were mildly satisfied with cupping and sham cupping; and only minor side effects were observed. Despite cupping therapy being more effective than usual care to improve pain intensity and quality of life, effects of cupping therapy were small and comparable to those of a sham treatment, and as such cupping cannot be recommended for fibromyalgia at the current time. PMID:27853272
Lauche, Romy; Spitzer, Julia; Schwahn, Barbara; Ostermann, Thomas; Bernardy, Kathrin; Cramer, Holger; Dobos, Gustav; Langhorst, Jost
2016-11-17
This study aimed to test the efficacy of cupping therapy to improve symptoms and quality of life in patients diagnosed with the fibromyalgia syndrome. Participants were randomly assigned to cupping therapy, sham or usual care. Cupping was administered five times at twice weekly intervals on the upper and lower back. The primary outcome measure was pain intensity at day 18. Secondary outcomes included functional disability, quality of life, fatigue and sleep quality as well as pressure pain sensitivity, satisfaction and safety at day 18 and 6 months. Altogether 141 patients were included in this study (139 females, 55.8 ± 9.1 years). After 18 days patients reported significant less pain after cupping compared to usual care (difference -12.4; 95% CI: -18.9; -5.9, p < 0.001) but not compared to sham (difference -3.0; 95% CI: -9.9, 3.9, p = 0.396). Further effects were found for quality of life compared to usual care. Patients were mildly satisfied with cupping and sham cupping; and only minor side effects were observed. Despite cupping therapy being more effective than usual care to improve pain intensity and quality of life, effects of cupping therapy were small and comparable to those of a sham treatment, and as such cupping cannot be recommended for fibromyalgia at the current time.
Dual-water mixture fuel burner
Brown, Thomas D.; Reehl, Douglas P.; Walbert, Gary F.
1986-08-05
A coal-water mixture (CWM) burner includes a conically shaped rotating cup into which fuel comprised of coal particles suspended in a slurry is introduced via a first, elongated inner tube coupled to a narrow first end portion of the cup. A second, elongated outer tube is coaxially positioned about the first tube and delivers steam to the narrow first end of the cup. The fuel delivery end of the inner first tube is provided with a helical slot on its lateral surface for directing the CWM onto the inner surface of the rotating cup in the form of a uniform, thin sheet which, under the influence of the cup's centrifugal force, flows toward a second, open, expanded end portion of the rotating cup positioned immediately adjacent to a combustion chamber. The steam delivered to the rotating cup wets its inner surface and inhibits the coal within the CWM from adhering to the rotating cup. A primary air source directs a high velocity air flow coaxially about the expanded discharge end of the rotating cup for applying a shear force to the CWM in atomizing the fuel mixture for improved combustion. A secondary air source directs secondary air into the combustion chamber adjacent to the outlet of the rotating cup at a desired pitch angle relative to the fuel mixture/steam flow to promote recirculation of hot combustion gases within the ignition zone for increased flame stability.
Fluctuation of Cup Orientation During Press-Fit Insertion: A Possible Cause of Malpositioning.
Nishii, Takashi; Sakai, Takashi; Takao, Masaki; Sugano, Nobuhiko
2015-10-01
We evaluated real-time angular changes during press-fit cup insertion in 70 total hip arthroplasties. Inclination and anteversion cup angles on navigation system were recorded after each procedure of five hammer blows during cup insertion, and maximum deviated inclination (MDI) and anteversion (MDA) angles until the cup was fully seated were measured. We found 1 (1%) and 29 (41%) hips with increases and decreases in MDI of 5° or more, and 13 (19%) and 6 (8%) hips with increases and decreases in MDA of 5° or more, respectively. The MDI in men was significantly lower and the MDA for left-side surgery was significantly higher. Surgeons should pay attention to fluctuation in angular changes during cup insertion and may consider countermeasures to minimize cup malpositioning. Copyright © 2015 Elsevier Inc. All rights reserved.
Gene Expression Profiling of the Intact Dermal Sheath Cup of Human Hair Follicles.
Niiyama, Shiro; Ishimatsu-Tsuji, Yumiko; Nakazawa, Yosuke; Yoshida, Yuzo; Soma, Tsutomu; Ideta, Ritsuro; Mukai, Hideki; Kishimoto, Jiro
2018-04-24
Cells that constitute the dermal papillae of hair follicles might be derived from the dermal sheath, the peribulbar component of which is the dermal sheath cup. The dermal sheath cup is thought to include the progenitor cells of the dermal papillae and possesses hair inductive potential; however, it has not yet been well characterized. This study investigated the gene expression profile of the intact dermal sheath cup, and identified dermal sheath cup signature genes, including extracellular matrix components and BMP-binding molecules, as well as TGF-b1 as an upstream regulator. Among these, GREM2, a member of the BMP antagonists, was found by in situ hybridization to be highly specific to the dermal sheath cup, implying that GREM2 is a key molecule contributing to maintenance of the properties of the dermal sheath cup.
Emerich, M; Braeunig, M; Clement, H W; Lüdtke, R; Huber, R
2014-02-01
Cupping worldwide has been part of traditional medicine systems and is in the western world used as CAM therapy mainly for treating pain syndromes. The mode of action is up to now unclear. In order to investigate its mechanism we measured in parallel metabolic changes in the tissue under the cupping glass and pressure pain thresholds. In 12 volunteers (6 healthy subjects and 6 patients with chronic neck pain) a microdialysis system was implanted subcutaneously on both sides (left and right) above the trapezius muscle. After baseline measures cupping was performed at one randomly selected side (left or right), the other side served as control. Every 20 min during baseline measures and for 280 min after cupping, microdialysis probes for detection of lactate, pyruvate, glucose and glycerin were taken. In addition, pain thresholds were measured before and after cupping with algometry. Cupping resulted in a strong increase of lactate (beginning 160 min after cupping until the end of the measurements) and the lactate/pyruvate ratio, indicating an anaerobe metabolism in the surrounding tissue. Baseline pain thresholds were non-significantly lower in neck pain patients compared to healthy controls and slightly increased immediately after cupping (p<0.05 compared to baseline close to the area of cupping in healthy subjects and on the foot in neck pain patients). After 280 min no more significant changes of pain thresholds were detected. Cupping induces >280 min lasting anaerobe metabolism in the subcutaneous tissue and increases immediate pressure pain thresholds in some areas. Copyright © 2014 Elsevier Ltd. All rights reserved.
Germline genetics of cancer of unknown primary (CUP) and its specific subtypes.
Hemminki, Kari; Chen, Bowang; Kumar, Abhishek; Melander, Olle; Manjer, Jonas; Hallmans, Göran; Pettersson-Kymmer, Ulrika; Ohlsson, Claes; Folprecht, Gunnar; Löffler, Harald; Krämer, Alwin; Försti, Asta
2016-04-19
Cancer of unknown primary site (CUP) is a fatal cancer diagnosed through metastases at various organs. Little is known about germline genetics of CUP which appears worth of a search in view of reported familial associations in CUP. In the present study, samples from CUP patients were identified from 2 Swedish biobanks and a German clinical trial, totaling 578 CUP patients and 7628 regionally matched controls. Diagnostic data specified the organ where metastases were diagnosed. We carried out a genome-wide association study on CUP cases and controls. In the whole sample set, 6 loci reached an allelic p-value in the range of 10-7 and were supported by data from the three centers. Three associations were located next to non-coding RNA genes. rs2660852 flanked 5'UTR of LTA4H (leukotriene A4 hydrolase), rs477145 was intronic to TIAM1 (T-cell lymphoma invasion and metastases) and rs2835931 was intronic to KCNJ6 (potassium channel, inwardly rectifying subfamily J, member 6). In analysis of subgroups of CUP patients (smokers, non-smokers and CUP with liver metastases) genome-wide significant associations were noted. For patients with liver metastases associations on chromosome 6 and 11, the latter including a cluster of genes DHCR7 and NADSYN1, encoding key enzymes in cholesterol and NAD synthesis, and KRTAP5-7, encoding a keratin associated protein. This first GWAS on CUP provide preliminary evidence that germline genes relating to inflammation (LTA4H), metastatic promotion (TIAM1) in association with lipid metabolic disturbance (chromosome 11 cluster) may contribute to the risk of CUP.
Factors influencing initial cup stability in total hip arthroplasty.
Amirouche, Farid; Solitro, Giovanni; Broviak, Stefanie; Gonzalez, Mark; Goldstein, Wayne; Barmada, Riad
2014-12-01
One of the main goals in total hip replacement is to preserve the integrity of the hip kinematics, by well positioning the cup and to make sure its initial stability is congruent and attained. Achieving the latter is not trivial. A finite element model of the cup-bone interface simulating a realistic insertion and analysis of different scenarios of cup penetration, insertion, under-reaming and loading is investigated to determine certain measurable factors sensitivity to stress-strain outcome. The insertion force during hammering and its relation to the cup penetration during implantation is also investigated with the goal of determining the initial stability of the acetabular cup during total hip arthroplasty. The mathematical model was run in various configurations to simulate 1 and 2mm of under-reaming at various imposed insertion distances to mimic hammering and insertion of cup insertion into the pelvis. Surface contact and micromotion at the cup-bone interface were evaluated after simulated cup insertion and post-operative loading conditions. The results suggest a direct correlation between under-reaming and insertion force used to insert the acetabular cup on the micromotion and fixation at the cup-bone interface. While increased under-reaming and insertion force result in an increase amount of stability at the interface, approximately the same percentage of surface contact and micromotion reduction can be achieved with less insertion force. We need to exercise caution to determine the optimal configuration which achieves a good conformity without approaching the yield strength for bone. Copyright © 2014 Elsevier Ltd. All rights reserved.
29 CFR 1910.241 - Definitions.
Code of Federal Regulations, 2011 CFR
2011-07-01
... reinforced does not cover wheels using such mechanical additions as steel rings, steel cup backs or wire or tape winding. (8) Type 11 flaring cup wheels. Type 11 flaring cup wheels have double diameter... mounting listed for Type 6 straight sided cup wheels definition in subparagraph (9) of this paragraph. Type...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-06
... INTERNATIONAL TRADE COMMISSION [Inv. No. 337-TA-835] Certain Food Containers, Cups, Plates... the sale within the United States after importation of certain food containers, cups, plates, cutlery... importation, or the sale within the United States after importation of certain food containers, cups, plates...
21 CFR 884.5400 - Menstrual cup.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Menstrual cup. 884.5400 Section 884.5400 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES... cup. (a) Identification. A menstrual cup is a receptacle placed in the vagina to collect menstrual...
29 CFR 1910.241 - Definitions.
Code of Federal Regulations, 2010 CFR
2010-07-01
... reinforced does not cover wheels using such mechanical additions as steel rings, steel cup backs or wire or tape winding. (8) Type 11 flaring cup wheels. Type 11 flaring cup wheels have double diameter... mounting listed for Type 6 straight sided cup wheels definition in subparagraph (9) of this paragraph. Type...
21 CFR 884.5400 - Menstrual cup.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Menstrual cup. 884.5400 Section 884.5400 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES... cup. (a) Identification. A menstrual cup is a receptacle placed in the vagina to collect menstrual...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-03-09
... INTERNATIONAL TRADE COMMISSION [DN 2883] Certain Food Containers, Cups, Plates, Cutlery, and... Containers, Cups, Plates, Cutlery, and Related Items, and Packaging Thereof, DN 2883; the Commission is... importation of certain food containers, cups, plates, cutlery, and related items, and packaging thereof. The...
21 CFR 884.5400 - Menstrual cup.
Code of Federal Regulations, 2013 CFR
2013-04-01
... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Menstrual cup. 884.5400 Section 884.5400 Food and... OBSTETRICAL AND GYNECOLOGICAL DEVICES Obstetrical and Gynecological Therapeutic Devices § 884.5400 Menstrual cup. (a) Identification. A menstrual cup is a receptacle placed in the vagina to collect menstrual...
21 CFR 884.5400 - Menstrual cup.
Code of Federal Regulations, 2012 CFR
2012-04-01
... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Menstrual cup. 884.5400 Section 884.5400 Food and... OBSTETRICAL AND GYNECOLOGICAL DEVICES Obstetrical and Gynecological Therapeutic Devices § 884.5400 Menstrual cup. (a) Identification. A menstrual cup is a receptacle placed in the vagina to collect menstrual...
21 CFR 884.5400 - Menstrual cup.
Code of Federal Regulations, 2014 CFR
2014-04-01
... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Menstrual cup. 884.5400 Section 884.5400 Food and... OBSTETRICAL AND GYNECOLOGICAL DEVICES Obstetrical and Gynecological Therapeutic Devices § 884.5400 Menstrual cup. (a) Identification. A menstrual cup is a receptacle placed in the vagina to collect menstrual...
77 FR 40630 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2012-07-10
... the United States against terrorist and foreign intelligence threats and to enforce U.S. criminal laws..., informants, sources, bystanders, law enforcement personnel, intelligence personnel, other responders... intelligence operation; individuals who are identified in open source information or commercial databases, or...
NASA Technical Reports Server (NTRS)
2004-01-01
KENNEDY SPACE CENTER, FLA. In the Orbiter Processing Facility, Jay Feaster, general manager of the National Hockey League 2004 Champions Tampa Bay Lightning, sits next to the Stanley Cup in front of the open hatch into Discovery. The cup was also briefly available for viewing by employees in the KSC Training Auditorium. Feaster brought the cup to KSC while on a tour. The Stanley Cup weighs 35 pounds and is more than 100 years old. The Lightning will be added to the cup in September.
NASA Technical Reports Server (NTRS)
2004-01-01
KENNEDY SPACE CENTER, FLA. Jay Feaster, general manager of the National Hockey League 2004 Champions Tampa Bay Lightning, stands next to the Stanley Cup, which he brought to KSC while on a tour. The cup stands next to the orbiter Discovery in the Orbiter Processing Facility. The cup was also briefly available for viewing by employees in the KSC Training Auditorium. The Stanley Cup weighs 35 pounds and is more than 100 years old. The Lightning will be added to the cup in September.
NASA Technical Reports Server (NTRS)
2004-01-01
KENNEDY SPACE CENTER, FLA. Jack Legere, NASA Quality Assurance specialist for the Shuttle Program, displays the Stanley Cup to employees in the Orbiter Processing Facility. Behind him is Discovery. Jay Feaster, general manager of the National Hockey League 2004 Champions Tampa Bay Lightning, brought the cup to KSC while on a tour. The cup was also briefly available for viewing by employees in the KSC Training Auditorium. The Stanley Cup weighs 35 pounds and is more than 100 years old. The Lightning will be added to the cup in September.
ARTIFICIAL INTELLIGENCE , RECURSIVE FUNCTIONS), (*RECURSIVE FUNCTIONS, ARTIFICIAL INTELLIGENCE ), (*MATHEMATICAL LOGIC, ARTIFICIAL INTELLIGENCE ), METAMATHEMATICS, AUTOMATA, NUMBER THEORY, INFORMATION THEORY, COMBINATORIAL ANALYSIS
Supporting tactical intelligence using collaborative environments and social networking
NASA Astrophysics Data System (ADS)
Wollocko, Arthur B.; Farry, Michael P.; Stark, Robert F.
2013-05-01
Modern military environments place an increased emphasis on the collection and analysis of intelligence at the tactical level. The deployment of analytical tools at the tactical level helps support the Warfighter's need for rapid collection, analysis, and dissemination of intelligence. However, given the lack of experience and staffing at the tactical level, most of the available intelligence is not exploited. Tactical environments are staffed by a new generation of intelligence analysts who are well-versed in modern collaboration environments and social networking. An opportunity exists to enhance tactical intelligence analysis by exploiting these personnel strengths, but is dependent on appropriately designed information sharing technologies. Existing social information sharing technologies enable users to publish information quickly, but do not unite or organize information in a manner that effectively supports intelligence analysis. In this paper, we present an alternative approach to structuring and supporting tactical intelligence analysis that combines the benefits of existing concepts, and provide detail on a prototype system embodying that approach. Since this approach employs familiar collaboration support concepts from social media, it enables new-generation analysts to identify the decision-relevant data scattered among databases and the mental models of other personnel, increasing the timeliness of collaborative analysis. Also, the approach enables analysts to collaborate visually to associate heterogeneous and uncertain data within the intelligence analysis process, increasing the robustness of collaborative analyses. Utilizing this familiar dynamic collaboration environment, we hope to achieve a significant reduction of time and skill required to glean actionable intelligence in these challenging operational environments.
[Development of lipoma following a single cupping massage - a case report].
Schumann, Stefan; Lauche, Romy; Hohmann, Claudia; Zirbes, Thomas; Dobos, Gustav; Saha, Felix Joyonto
2012-01-01
The cupping massage is a form of bloodless cupping. This type of cupping is particularly used to treat muscular tension and musculoskeletal pain, such as chronic neck pain; however the data records on mechanisms and potential side effects are not satisfactory. In a study on the effectiveness of cupping massage in patients with chronic neck pain, one patient showed a formation of a lipoma in the cupping area after the first treatment session. Because of the short time interval between therapy and development of the lipoma, a primary cause is not realistic. This adverse event has not been described in the literature before, and the present report describes the case in summary.
Evaluation of Porcelain Cup Soil Water Samplers for Bacteriological Sampling1
Dazzo, Frank B.; Rothwell, Donald F.
1974-01-01
The validity of obtaining soil water for fecal coliform analyses by porcelain cup soil water samplers was examined. Numbers from samples of manure slurry drawn through porcelain cups were reduced 100- to 10,000,000-fold compared to numbers obtained from the external manure slurry, and 65% of the cups yielded coliform-free samples. Fecal coliforms adsorbed to cups apparently were released, thus influencing the counts of subsequent samples. Fecal coliforms persisted in soil water samplers buried in soil and thus could significantly influence the coliform counts of water samples obtained a month later. These studies indicate that porcelain cup soil water samplers do not yield valid water samples for fecal coliform analyses. Images PMID:16349998
Capturing and Modeling Domain Knowledge Using Natural Language Processing Techniques
2005-06-01
Intelligence Artificielle , France, May 2001, p. 109- 118 [Barrière, 2001] -----. “Investigating the Causal Relation in Informative Texts”. Terminology, 7:2...out of the flood of information, military have to create new ways of processing sensor and intelligence information, and of providing the results to...have to create new ways of processing sensor and intelligence information, and of providing the results to commanders who must take timely operational
Li, Ting; Li, Yaoxian; Lin, Yu; Li, Kai
2017-01-01
Cupping therapy has been used in traditional Chinese medicine for thousands of years to relieve muscle pain/tendency/fatigue and to cure or reduce symbols of other diseases. However, its therapeutic effect is sparsely interpreted in the language of modern physiology. To objectively evaluate its therapeutic effect, we focused on dry cupping treatment and utilized near-infrared spectroscopy (NIRS) to assess the concentration change in oxy-hemoglobin ([HbO 2 ]), deoxy-hemoglobin ([Hb]), and blood volume in the course of cupping therapy over 13 volunteers on the infraspinatus muscle, where is usually applied for shoulder pains. Both a prominent drop in [Hb] and a significant elevation in [HbO 2 ] in the tissue surrounding the cupping site were observed during both cupping and post-treatment, manifesting the enhancement of oxygen uptake. This resulting promotion indicates potential positive therapeutic effect of cupping therapy in hemodynamics for facilitating muscular functions.
Proteomic effects of wet cupping (Al-hijamah).
Almaiman, Amer A
2018-01-01
Wet cupping (Al-hijamah) is a therapeutic technique practiced worldwide as a part of the Unani system of medicine. It involves bloodletting from acupoints on a patient's skin to produce a therapeutic outcome. A thorough review of research articles on wet cupping with relevance to proteomics field that are indexed by Google Scholar, PubMed, and/or Science Direct databases was performed. Eight original research articles were summarized in this paper. Overall, wet cupping did not have a significant effect on C-reactive protein, Hsp-27, sister chromatid exchanges, and cell replication index. In contrast, wet cupping was found to produce higher oxygen saturation, eliminate lactate from subcutaneous tissues, remove blood containing higher levels of malondialdehyde and nitric oxide, and produce higher activity of myeloperoxidase. The proteomic effects of wet cupping therapy have not been adequately investigated. Thus, future studies on wet cupping that use systemic and sound protocols to avoid bias should be conducted.
Paradoxical, Cupping-Induced Localized Psoriasis: A Koebner Phenomenon.
Vender, Reid; Vender, Ronald
2015-01-01
Cupping therapy is a traditional Chinese medicine used to heal psoriasis. The Koebner phenomenon is the occurrence of psoriatic lesions at the site of cutaneous injury. To describe the first case of biopsy-proven cupping-induced localized psoriasis, an example of the Koebner phenomenon. The histopathology of the lesions is described. A brief review of the literature regarding cupping therapy and its efficacy are discussed. A 45-year-old Asian male presented himself to the dermatology clinic for further treatment of his psoriasis. Four unusually circular plaques on the lower back were discovered. Pathologic diagnosis revealed an early lesion of psoriasis. on further inquiry, the patient admitted to undergoing a recent "cupping" procedure in an attempt to cure his condition. The efficacy of cupping therapy is controversial, and psoriatic patients may develop localized psoriasis through koebnerization as a result of cupping therapy rather than achieve desirable therapeutic benefits. © 2014 Canadian Dermatology Association.
Proteomic effects of wet cupping (Al-hijamah)
Almaiman, Amer A.
2018-01-01
Wet cupping (Al-hijamah) is a therapeutic technique practiced worldwide as a part of the Unani system of medicine. It involves bloodletting from acupoints on a patient’s skin to produce a therapeutic outcome. A thorough review of research articles on wet cupping with relevance to proteomics field that are indexed by Google Scholar, PubMed, and/or Science Direct databases was performed. Eight original research articles were summarized in this paper. Overall, wet cupping did not have a significant effect on C-reactive protein, Hsp-27, sister chromatid exchanges, and cell replication index. In contrast, wet cupping was found to produce higher oxygen saturation, eliminate lactate from subcutaneous tissues, remove blood containing higher levels of malondialdehyde and nitric oxide, and produce higher activity of myeloperoxidase. The proteomic effects of wet cupping therapy have not been adequately investigated. Thus, future studies on wet cupping that use systemic and sound protocols to avoid bias should be conducted. PMID:29332103
Automated volumetric evaluation of stereoscopic disc photography
Xu, Juan; Ishikawa, Hiroshi; Wollstein, Gadi; Bilonick, Richard A; Kagemann, Larry; Craig, Jamie E; Mackey, David A; Hewitt, Alex W; Schuman, Joel S
2010-01-01
PURPOSE: To develop a fully automated algorithm (AP) to perform a volumetric measure of the optic disc using conventional stereoscopic optic nerve head (ONH) photographs, and to compare algorithm-produced parameters with manual photogrammetry (MP), scanning laser ophthalmoscope (SLO) and optical coherence tomography (OCT) measurements. METHODS: One hundred twenty-two stereoscopic optic disc photographs (61 subjects) were analyzed. Disc area, rim area, cup area, cup/disc area ratio, vertical cup/disc ratio, rim volume and cup volume were automatically computed by the algorithm. Latent variable measurement error models were used to assess measurement reproducibility for the four techniques. RESULTS: AP had better reproducibility for disc area and cup volume and worse reproducibility for cup/disc area ratio and vertical cup/disc ratio, when the measurements were compared to the MP, SLO and OCT methods. CONCLUSION: AP provides a useful technique for an objective quantitative assessment of 3D ONH structures. PMID:20588996
78 FR 32635 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2013-05-31
...; System of Records AGENCY: National Geospatial-Intelligence Agency, DoD. ACTION: Notice to Add a New System of Records. SUMMARY: The National Geospatial-Intelligence Agency is establishing a new system of... information. FOR FURTHER INFORMATION CONTACT: National Geospatial-Intelligence Agency [[Page 32636
21 CFR 872.6290 - Prophylaxis cup.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Prophylaxis cup. 872.6290 Section 872.6290 Food... DEVICES DENTAL DEVICES Miscellaneous Devices § 872.6290 Prophylaxis cup. (a) Identification. A prophylaxis cup is a device made of rubber intended to be held by a dental handpiece and used to apply polishing...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-04-24
...-AA08 Special Local Regulation; Hebda Cup Rowing Regatta, Trenton Channel; Detroit River, Wyandotte, MI..., during, and immediately after the Hebda Cup Rowing Regatta. This special local regulation will establish... this boat race. It is also unnecessary to solicit public comments because the Hebda Cup Rowing Regatta...
21 CFR 872.6290 - Prophylaxis cup.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Prophylaxis cup. 872.6290 Section 872.6290 Food... DEVICES DENTAL DEVICES Miscellaneous Devices § 872.6290 Prophylaxis cup. (a) Identification. A prophylaxis cup is a device made of rubber intended to be held by a dental handpiece and used to apply polishing...
76 FR 39289 - Special Local Regulation; Detroit APBA Gold Cup, Detroit River, Detroit, MI
Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-06
...-AA08 Special Local Regulation; Detroit APBA Gold Cup, Detroit River, Detroit, MI AGENCY: Coast Guard... immediately after the Detroit APBA Gold Cup boat race. This special local regulation will establish... entry found in 33 CFR 100.918, Detroit APBA Gold Cup, Detroit, MI. Currently, the regulations located at...
29 CFR 1910.211 - Definitions.
Code of Federal Regulations, 2011 CFR
2011-07-01
... having a diameter, thickness and wall—wheel is mounted on the diameter. (3) Type 6 straight cup wheels...—Type 6 Straight Cup Wheels EC27OC91.054 Type 6—Straight-cup Wheel Side grinding wheel having a diameter... describe this shape type. (4) Type 11 flaring cup wheels mean wheels having double diameter dimensions D...
75 FR 39448 - Special Local Regulation; Detroit APBA Gold Cup, Detroit River, Detroit, MI
Federal Register 2010, 2011, 2012, 2013, 2014
2010-07-09
...-AA08 Special Local Regulation; Detroit APBA Gold Cup, Detroit River, Detroit, MI AGENCY: Coast Guard... APBA Gold Cup. This special local regulation is necessary to protect spectators and vessels from the... Regulation; Detroit APBA Gold Cup, Detroit River, Detroit, MI in the Federal Register (75 FR 21191). We...
76 FR 53051 - Safety Zone; ISAF Nations Cup Grand Final Fireworks Display, Sheboygan, WI
Federal Register 2010, 2011, 2012, 2013, 2014
2011-08-25
...-AA00 Safety Zone; ISAF Nations Cup Grand Final Fireworks Display, Sheboygan, WI AGENCY: Coast Guard.... Background and Purpose The ISAF Nations Cup Grand Final fireworks are a City permitted fireworks display that.... 165.T09-0755 Safety Zone; ISAF Nations Cup Grand Final Fireworks Display, Sheboygan, Wisconsin. (a...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-12-10
...-AA00; 1625-AA08 Special Local Regulation and Safety Zone; America's Cup Sailing Events, San Francisco... the 2013 America's Cup events. This document corrects those erroneous coordinates. DATES: Effective on... published a temporary final rule regulating the on-water activities associated with the ``Louis Vuitton Cup...
75 FR 21191 - Special Local Regulation; Detroit APBA Gold Cup, Detroit River, Detroit, MI
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-23
...-AA08 Special Local Regulation; Detroit APBA Gold Cup, Detroit River, Detroit, MI AGENCY: Coast Guard... the Detroit APBA Gold Cup. This special local regulation is necessary to protect spectators and... race in conjunction with the Detroit APBA Gold Cup. The powerboat race and associated testing will...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-27
...-AA08 Special Local Regulation; Hebda Cup Rowing Regatta, Trenton Channel; Detroit River, Wyandotte, MI..., during, and immediately after the Hebda Cup Rowing Regatta. This special local regulation will establish....35T09-0340 Special Local Regulation; Hebda Cup Rowing Regatta, Wyandotte, MI. (a) Regulated area. A...
Calcium and Vitamin D: Important at Every Age
... 100 Turnip greens, boiled, ½ cup 99 Broccoli, raw, 1 cup 90 Ice cream, vanilla, ½ cup 85 Soy or rice milk, fortified with calcium, 1 cup 80–500 (varies) Calcium Culprits Although a balanced diet aids calcium absorption, high levels of protein and sodium (salt) in the diet are thought ...
Dummy Cup Helps Robot-Welder Programmers
NASA Technical Reports Server (NTRS)
Gordon, Stephen S.
1990-01-01
Dummy gas cup used on torch of robotic welder during programming and practice runs. Made of metal or plastic, dummy cup inexpensive and durable. Withstands bumps caused by programming errors, and is sized for special welding jobs within limited clearances. After robot satisfactorily programmed, replaced by ceramic cup of same dimensions for actual welding.
77 FR 7025 - Safety Zones; America's Cup World Series, East Passage, Narragansett Bay, RI
Federal Register 2010, 2011, 2012, 2013, 2014
2012-02-10
...-AA00 Safety Zones; America's Cup World Series, East Passage, Narragansett Bay, RI AGENCY: Coast Guard... the America's Cup World Series sailing vessel racing event. This safety zone is intended to safeguard... participants and spectators involved with the America's Cup World Series in the vicinity of Newport, RI...
77 FR 28253 - Safety Zone; America's Cup World Series, East Passage, Narragansett Bay, RI
Federal Register 2010, 2011, 2012, 2013, 2014
2012-05-14
...-AA00 Safety Zone; America's Cup World Series, East Passage, Narragansett Bay, RI AGENCY: Coast Guard... navigable waters of the East Passage, Narragansett Bay, Rhode Island, during the America's Cup World Series... rulemaking (NPRM) entitled ``Safety Zones; America's Cup World Series, East Passage, Narragansett Bay, RI...
NASA Astrophysics Data System (ADS)
Harun, D.; Zulfadhli; Akhyar, H.
2018-05-01
The turbine ventilator is a wind turbine with a vertical axis that has a combined function of the wind turbine and a suction fan. In this study, the turbine ventilator modified by adding a wind cup on the top (cap) turbine ventilator. The purpose of this experiment is to investigated the effect of the addition of wind cup on the turbine ventilator. Turbine ventilator used is type v30 and wind cup with diameter 77 mm. The experiment was conducted using a triangular pentagon model space chamber which was cut off to place the ventilator turbine ventilation cup with a volume of 0.983 m3 (equivalent to 1 mm3). The results of this study indicate that at an average wind speed of 1.8 m/s, the rotation of the turbine produced without a wind cup is 60.6 rpm while with the addition of a wind cup in the turbine ventilator is 69 rpm. The average increase of rotation turbine after added win cup is 8.4 rpm and the efficiency improvement of turbine ventilator is 1.7 %.
Segmentation of optic disc and optic cup in retinal fundus images using shape regression.
Sedai, Suman; Roy, Pallab K; Mahapatra, Dwarikanath; Garnavi, Rahil
2016-08-01
Glaucoma is one of the leading cause of blindness. The manual examination of optic cup and disc is a standard procedure used for detecting glaucoma. This paper presents a fully automatic regression based method which accurately segments optic cup and disc in retinal colour fundus image. First, we roughly segment optic disc using circular hough transform. The approximated optic disc is then used to compute the initial optic disc and cup shapes. We propose a robust and efficient cascaded shape regression method which iteratively learns the final shape of the optic cup and disc from a given initial shape. Gradient boosted regression trees are employed to learn each regressor in the cascade. A novel data augmentation approach is proposed to improve the regressors performance by generating synthetic training data. The proposed optic cup and disc segmentation method is applied on an image set of 50 patients and demonstrate high segmentation accuracy for optic cup and disc with dice metric of 0.95 and 0.85 respectively. Comparative study shows that our proposed method outperforms state of the art optic cup and disc segmentation methods.
The Transverse Acetabular Ligament as an Intraoperative Guide to Cup Abduction.
Hiddema, Willem B; van der Merwe, Johan F; van der Merwe, Werner
2016-07-01
The success of a total hip arthroplasty relies on optimal acetabular cup placement to ensure mating of the femoral head and acetabular cup throughout all positions of the hip joint. Poor cup placement is associated with dislocation, impingement, microseparation, component loosening, and accelerated wear due to rim loading. This study examined a novel method of using the transverse acetabular ligament (TAL) to guide cup inclination during primary total hip arthroplasty. A descriptive study using 16 hips from 9 cadavers. A computer navigation system measured inclination and version of the acetabular component in 3 positions with the lower edge of cup: (1) flush with, (2) 5 mm proximal to, and (3) 5 mm distal to free border of the TAL. The median inclination angles were 44° in position (1), 30° in position (2), and 64° in position (3). The median anteversion angle for all positions was 19°. Cup inclination was acceptable when the lower edge of the cup was flush or within 5 mm proximal to the TAL. Copyright © 2016 Elsevier Inc. All rights reserved.
Miyake, Kentaro; Kiyuna, Tasuku; Miyake, Masuyo; Kawaguchi, Kei; Yoon, Sang Nam; Zhang, Zhiying; Igarashi, Kentaro; Razmjooei, Sahar; Wangsiricharoen, Sintawat; Murakami, Takashi; Li, Yunfeng; Nelson, Scott D; Russell, Tara A; Singh, Arun S; Hiroshima, Yukihiko; Momiyama, Masashi; Matsuyama, Ryusei; Chishima, Takashi; Singh, Shree Ram; Endo, Itaru; Eilber, Fritz C; Hoffman, Robert M
2018-01-01
Cancer of unknown primary (CUP) is a recalcitrant disease with poor prognosis because it lacks standard first-line therapy. CUP consists of diverse malignancy groups, making personalized precision therapy essential. The present study aimed to identify an effective therapy for a CUP patient using a patient-derived orthotopic xenograft (PDOX) model. This paper reports the usefulness of the PDOX model to precisely identify effective and ineffective chemotherapy and to compare the efficacy of S. typhimurium A1-R with first-line chemotherapy using the CUP PDOX model. The present study is the first to use a CUP PDOX model, which was able to precisely distinguish the chemotherapeutic course. We found that a carboplatinum (CAR)-based regimen was effective for this CUP patient. We also demonstrated that S. typhimurium A1-R was more effective against the CUP tumor than first-line chemotherapy. Our results indicate that S. typhimurium A1-R has clinical potential for CUP, a resistant disease that requires effective therapy.
User modeling for distributed virtual environment intelligent agents
NASA Astrophysics Data System (ADS)
Banks, Sheila B.; Stytz, Martin R.
1999-07-01
This paper emphasizes the requirement for user modeling by presenting the necessary information to motivate the need for and use of user modeling for intelligent agent development. The paper will present information on our current intelligent agent development program, the Symbiotic Information Reasoning and Decision Support (SIRDS) project. We then discuss the areas of intelligent agents and user modeling, which form the foundation of the SIRDS project. Included in the discussion of user modeling are its major components, which are cognitive modeling and behavioral modeling. We next motivate the need for and user of a methodology to develop user models to encompass work within cognitive task analysis. We close the paper by drawing conclusions from our current intelligent agent research project and discuss avenues of future research in the utilization of user modeling for the development of intelligent agents for virtual environments.
User-defined functions in the Arden Syntax: An extension proposal.
Karadimas, Harry; Ebrahiminia, Vahid; Lepage, Eric
2015-12-11
The Arden Syntax is a knowledge-encoding standard, started in 1989, and now in its 10th revision, maintained by the health level seven (HL7) organization. It has constructs borrowed from several language concepts that were available at that time (mainly the HELP hospital information system and the Regenstrief medical record system (RMRS), but also the Pascal language, functional languages and the data structure of frames, used in artificial intelligence). The syntax has a rationale for its constructs, and has restrictions that follow this rationale. The main goal of the Standard is to promote knowledge sharing, by avoiding the complexity of traditional programs, so that a medical logic module (MLM) written in the Arden Syntax can remain shareable and understandable across institutions. One of the restrictions of the syntax is that you cannot define your own functions and subroutines inside an MLM. An MLM can, however, call another MLM, where this MLM will serve as a function. This will add an additional dependency between MLMs, a known criticism of the Arden Syntax knowledge model. This article explains why we believe the Arden Syntax would benefit from a construct for user-defined functions, discusses the need, the benefits and the limitations of such a construct. We used the recent grammar of the Arden Syntax v.2.10, and both the Arden Syntax standard document and the Arden Syntax Rationale article as guidelines. We gradually introduced production rules to the grammar. We used the CUP parsing tool to verify that no ambiguities were detected. A new grammar was produced, that supports user-defined functions. 22 production rules were added to the grammar. A parser was built using the CUP parsing tool. A few examples are given to illustrate the concepts. All examples were parsed correctly. It is possible to add user-defined functions to the Arden Syntax in a way that remains coherent with the standard. We believe that this enhances the readability and the robustness of MLMs. A detailed proposal will be submitted by the end of the year to the HL7 workgroup on Arden Syntax. Copyright © 2015 Elsevier B.V. All rights reserved.
Busch, Vincent J J F; Verschueren, Joost; Adang, Eddy M; Lie, Stein A; Havelin, Leif I; Schreurs, Berend W
2016-01-01
Acetabular deficiencies in young patients can be restored in several ways during total hip arthroplasty. Currently, cementless cups are most frequently used. Impaction bone grafting of acetabular defects is a more biological approach, but is it cost-effective in young patients on the long term? We designed a decision model for a cost-utility analysis of a cemented cup with acetabular impaction bone grafting versus an uncemented cup, in terms of cost per quality-adjusted life year (QALY) for the young adult with acetabular bone deficiency, in need for a primary total hip arthroplasty. Outcome probabilities and effectiveness were derived from the Radboud University Nijmegen Medical Centre and the Norwegian Hip Register. Multiple sensitivity analyses were used to assess the contribution of the included variables in the model's outcome. Cemented cups with impaction bone grafting were more cost-effective compared to the uncemented option in terms of costs per QALY. A scenario suggesting equal primary survival rates of both cemented and uncemented cups still showed an effect gain of the cemented cup with impaction bone grafting, but at higher costs. Based on this model, the first choice of treatment of the acetabular bone deficient osteoarthritic hip in a young patient is reconstruction with impaction bone grafting and a cemented cup.
Initial stability of a highly porous titanium cup in an acetabular bone defect model.
Yoshimoto, Kensei; Nakashima, Yasuharu; Wakiyama, Miyo; Hara, Daisuke; Nakamura, Akihiro; Iwamoto, Mikio
2018-04-12
The purpose of this study was to quantify the initial stability of a highly porous titanium cup using an acetabular bone defect model. The maximum torque of a highly porous titanium cup, with a pore size of 640 μm and porosity of 60%, was measured using rotational and lever-out torque testing and compared to that of a titanium-sprayed cup. The bone models were prepared using a polyurethane foam block and had three levels of bone coverage: 100, 70, and 50%. The highly porous titanium cup demonstrated significantly higher maximum torque than the titanium-sprayed cups in the three levels of bone defects. On rotational torque testing, it was found to be 1.5, 1.3, and 1.3 times stronger than the titanium-sprayed cups with 100, 70 and 50% bone coverage, respectively. Furthermore, it was found to be 2.2, 2.3, and 1.5 times stronger on lever-out testing than the titanium-sprayed cup. No breakage in the porous layers was noted during the testing. This study provides additional evidence of the initial stability of highly porous titanium cup, even in the presence of acetabular bone defects. Copyright © 2018. Published by Elsevier B.V.
Finnilä, Sami; Moritz, Niko; SvedströM, Erkki; Alm, Jessica J; Aro, Hannu T
2016-02-01
Low bone mineral density (BMD) may jeopardize the initial component stability and delay osseointegration of uncemented acetabular cups in total hip arthroplasty (THA). We measured the migration of uncemented cups in women with low or normal BMD. We used radiostereometric analysis (RSA) to measure the migration of hydroxyapatite-coated titanium alloy cups with alumina-on-alumina bearings in THA of 34 female patients with a median age of 64 (41-78) years. 10 patients had normal BMD and 24 patients had low systemic BMD (T-score ≤ -1) based on dual-energy X-ray absorptiometry (DXA). Cup migration was followed with RSA for 2 years. Radiographic follow-up was done at a median of 8 (2-10) years. Patients with normal BMD did not show a statistically significant cup migration after the settling period of 3 months, while patients with low BMD had a continuous proximal migration between 3 and 12 months (p = 0.03). These differences in cup migration persisted at 24 months. Based on the perceived risk of cup revision, 14 of the 24 cases were "at risk" (proximal translation of 0.2 to 1.0 mm) in the low-BMD group and 2 of the 10 cases were "at risk" in the normal-BMD group (odds ratio (OR) = 8.0, 95% CI: 1.3-48). The radiographic follow-up showed no radiolucent lines or osteolysis. 2 cups have been revised for fractures of the ceramic bearings, but none for loosening. Low BMD contributed to cup migration beyond the settling period of 3 months, but the migrating cups appeared to osseointegrate eventually.
Coukell, Barrie; Li, Yi; Moniakis, John; Cameron, Anne
2004-01-01
Changes in free intracellular Ca2+ are thought to regulate several major processes during Dictyostelium development, including cell aggregation and cell type-specific gene expression, but the mechanisms involved are unclear. To learn more about Ca2+ signaling and Ca2+ homeostasis in this organism, we used suppression subtractive hybridization to identify genes up-regulated by high extracellular Ca2+. Unexpectedly, many of the genes identified belong to a novel gene family (termed cup) with seven members. In vegetative cells, the cup genes were up-regulated by high Ca2+ but not by other ions or by heat, oxidative, or osmotic stress. cup induction by Ca2+ was blocked completely by inhibitors of calcineurin and protein synthesis. In developing cells, cup expression was high during aggregation and late development but low during the slug stage. This pattern correlates closely with reported levels of free intracellular Ca2+ during development. The cup gene products are highly homologous, acidic proteins possessing putative ricin domains. BLAST searches failed to reveal homologs in other organisms, but Western analyses suggested that Cup-like proteins might exist in certain other cellular slime mold species. Localization experiments indicated that Cup proteins are primarily cytoplasmic but become cell membrane-associated during Ca2+ stress and cell aggregation. When cup expression was down-regulated by antisense RNA, the cells failed to aggregate. However, this developmental block was overcome by partially up-regulating cup expression. Together, these results suggest that the Cup proteins in Dictyostelium might play an important role in stabilizing and/or regulating the cell membrane during Ca2+ stress and/or certain stages of development. PMID:14871937
Measurement of Optic Disc Cup Surface Depth Using Cirrus HD-OCT.
Kim, Young Kook; Ha, Ahnul; Lee, Won June; Jeoung, Jin Wook; Park, Ki Ho
2017-12-01
To introduce the measurement method of optic disc cup surface depth using spectral-domain optical coherence tomography (SD-OCT) and then evaluate the rates of cup surface depression at 3 different stages of glaucoma. We retrospectively identified 52 eyes with preperimetric glaucoma, 56 with mild-or-moderate glaucoma and 50 with severe glaucoma and followed them for at least 48 months. Eyes were imaged using SD-OCT (Cirrus HD-OCT) at 12-month intervals. The mean cup surface depth was calculated using the following formula: Cup volume/(disc area×average cup-to-disc ratio)-200 μm. The rates of mean cup surface depression (μm/y) were significantly greater in mild-or-moderate glaucoma (-7.96±1.03) than in preperimetric (-3.11±0.61) and severe glaucoma (-0.70±0.12; all P<0.001). The percentile rates of mean cup surface depression (%/y) were significantly greater than those of average of retinal nerve fiber layer (RNFL) thinning (%/y) in preperimetric glaucoma (-1.64±0.12 vs. -1.11±0.07; P<0.001) and mild-or-moderate glaucoma (-4.20±0.33 vs. -3.14±0.19; P<0.001); and conversely, in severe glaucoma, mean cup surface depth changed slower than did average RNFL thickness (-0.64±0.06 vs. -0.75±0.08%/y; P<0.001). In early-to-moderate glaucoma, the cup surface depth changed faster than did the RNFL thickness. These results signify the possibility that SD-OCT-based estimation of cup surface depth might be useful for monitoring of glaucoma development and progression.
Morphological Features and Important Parameters of Large Optic Discs for Diagnosing Glaucoma
Okimoto, Satoshi; Yamashita, Keiko; Shibata, Tetsuo; Kiuchi, Yoshiaki
2015-01-01
Purpose To compare the optic disc parameters of glaucomatous eyes to those of non-glaucomatous eyes with large discs. Methods We studied 225 consecutive eyes with large optic discs (>2.82 mm2): 91 eyes with glaucoma and 134 eyes without glaucoma. An eye was diagnosed with glaucoma when visual field defects were detected by the Humphrey Field Analyzer. All of the Heidelberg Retina Tomograph II (HRT II) parameters were compared between the non-glaucomatous and glaucomatous eyes. A logistic regression analysis of the HRT II parameters was used to establish a new formula for diagnosing glaucoma, and the sensitivity and specificity of the Moorfields Regression Analysis (MRA) was compared to the findings made by our analyses. Results The mean disc area was 3.44±0.50 mm2 in the non-glaucomatous group and 3.40±0.52 mm2 in the glaucoma group. The cup area, cup volume, cup-to-disc area ratio, linear cup/disc ratio, mean cup depth, and the maximum cup depth were significantly larger in glaucomatous eyes than in the non-glaucomatous eyes. The rim area, rim volume, cup shape measurement, mean retinal nerve fiber layer (RNFL) thickness, and RFNL cross-sectional area were significantly smaller in glaucomatous eyes than in non-glaucomatous eyes. The cup-to-disc area ratio, the height variation contour (HVC), and the RNFL cross-sectional area were important parameters for diagnosing the early stage glaucoma, and the cup-to-disc area ratio and cup volume were useful for diagnosing advanced stage glaucoma in eyes with a large optic disc. The new formula had higher sensitivity and specificity for diagnosing glaucoma than MRA. Conclusions The cup-to-disc area ratio, HVC, RNFL cross-sectional area, and cup volume were important parameters for diagnosing glaucoma in eyes with a large optic disc. The important disc parameters to diagnose glaucoma depend on the stage of glaucoma in patients with large discs. PMID:25798580
Korduba, Laryssa A; Essner, Aaron; Pivec, Robert; Lancin, Perry; Mont, Michael A; Wang, Aiguo; Delanois, Ronald E
2014-10-01
The effect of acetabular component positioning on the wear rates of metal-on-polyethylene articulations has not been extensively studied. Placement of acetabular cups at abduction angles of more than 40° has been noted as a possible reason for early failure caused by increased wear. We conducted a study to evaluate the effects of different acetabular cup abduction angles on polyethylene wear rate, wear area, contact pressure, and contact area. Our in vitro study used a hip joint simulator and finite element analysis to assess the effects of cup orientation at 4 angles (0°, 40°, 50°, 70°) on wear and contact properties. Polyethylene bearings with 28-mm cobalt-chrome femoral heads were cycled in an environment mimicking in vivo joint fluid to determine the volumetric wear rate after 10 million cycles. Contact pressure and contact area for each cup abduction angle were assessed using finite element analysis. Results were correlated with cup abduction angles to determine if there were any differences among the 4 groups. The inverse relationship between volumetric wear rate and acetabular cup inclination angle demonstrated less wear with steeper cup angles. The largest abduction angle (70°) had the lowest contact area, largest contact pressure, and smallest head coverage. Conversely, the smallest abduction angle (0°) had the most wear and most head coverage. Polyethylene wear after total hip arthroplasty is a major cause of osteolysis and aseptic loosening, which may lead to premature implant failure. Several studies have found that high wear rates for cups oriented at steep angles contributed to their failure. Our data demonstrated that larger cup abduction angles were associated with lower, not higher, wear. However, this potentially "protective" effect is likely counteracted by other complications of steep cup angles, including impingement, instability, and edge loading. These factors may be more relevant in explaining why implants fail at a higher rate if cups are oriented at more than 40° of abduction.
Batailler, C; Bonin, N; M Wettstein; Nogier, A; Martres, S; Ollier, E; May, O; Lustig, S
2017-12-01
Impingement of the ilio-psoas tendon on the acetabular component is a cause of pain after total hip arthroplasty (THA). Studies of cup revision for ilio-psoas impingement (IPI) are scarce and limited in size. We therefore conducted a large multicentre retrospective study with the following objectives: to assess the effectiveness of cup replacement in resolving the impingement syndrome, to determine the frequency and nature of complications after cup revision for IPI, and to identify pre-operative factors associated with good outcomes of cup revision for IPI. Cup revision is effective in resolving the pain due to IPI in selected patients. This retrospective multicentre study included 46 patients who underwent cup revision because of IPI. Before the revision, 38 (83%) patients had prominence of the anterior cup rim (mean, 9.9±4.5mm (range, 2-22mm) by radiography and 35 (76%) had cup malposition (anteversion<10° and/or inclination>50°). Mean follow-up was 21months (range, 6months to 6 years) and no patient was lost to follow-up. Outcomes at last follow-up were assessed based on the Oxford Hip Score (OHS), patient satisfaction index, complications, and revisions. At last follow-up, 39 (85%) patients were satisfied with the revision procedure, a significant improvement versus baseline was noted in the OHS (mean, 43±6; range, 25-48; P<0.001), and 41 patients were free of pain during hip flexion (P<0.001 versus baseline). Complications occurred in 3 (6.5%) patients, but only one complication was severe (deep infection). Recurrent groin pain was reported by 4 (8.7%) patients at last follow-up. None of the factors studied predicted the outcome of revision surgery. Cup revision for IPI after THA is effective in relieving the groin pain in 80% of patients with anterior cup rim prominence and/or cup malposition. However, complications can occur. Tenotomy may be preferable when the diagnosis is in doubt and/or cup position is acceptable. IV, retrospective observational study. Published by Elsevier Masson SAS.
Does osteoporosis reduce the primary tilting stability of cementless acetabular cups?
von Schulze Pellengahr, Christoph; von Engelhardt, Lars V; Wegener, Bernd; Müller, Peter E; Fottner, Andreas; Weber, Patrick; Ackermann, Ole; Lahner, Matthias; Teske, Wolfram
2015-04-21
Cementless hip cups need sufficient primary tilting stability to achieve osseointegration. The aim of the study was to assess differences of the primary implant stability in osteoporotic bone and in bone with normal bone density. To assess the influence of different cup designs, two types of threaded and two types of press-fit cups were tested. The maximum tilting moment for two different cementless threaded cups and two different cementless press-fit cups was determined in macerated human hip acetabuli with reduced (n=20) and normal bone density (n=20), determined using Q-CT. The tilting moments for each cup were determined five times in the group with reduced bone density and five times in the group with normal bone density, and the respective average values were calculated. The mean maximum extrusion force of the threaded cup Zintra was 5670.5 N (max. tilting moment 141.8 Nm) in bone with normal density and.5748.3 N (max. tilting moment 143.7 Nm) in osteoporotic bone. For the Hofer Imhof (HI) threaded cup it was 7681.5 N (192.0 Nm) in bone with normal density and 6828.9 N (max. tilting moment 170.7 Nm) in the group with osteoporotic bone. The mean maximum extrusion force of the macro-textured press-fit cup Metallsockel CL was 3824.6 N (max. tilting moment 95.6 Nm) in bone with normal and 2246.2 N (max. tilting moment 56.2 Nm) in osteoporotic bone. For the Monoblock it was 1303.8 N (max. tilting moment 32.6 Nm) in normal and 1317 N (max. tilting moment 32.9 Nm) in osteoporotic bone. There was no significance. A reduction of the maximum tilting moment in osteoporotic bone of the ESKA press-fit cup Metallsockel CL was noticed. Results on macerated bone specimens showed no statistically significant reduction of the maximum tilting moment in specimens with osteoporotic bone density compared to normal bone, neither for threaded nor for the press-fit cups. With the limitation that the results were obtained using macerated bone, we could not detect any restrictions for the clinical indication of the examined cementless cups in osteoporotic bone.
Iwakiri, Kentaro; Kobayashi, Akio; Ohta, Yoichi; Minoda, Yukihide; Takaoka, Kunio; Nakamura, Hiroaki
2017-12-01
The acetabular component orientation in total hip arthroplasty (THA) is of critical importance to the good clinical results. However, traditional widely used cup alignment guides for cup placement are reported to be relatively unreliable. The present study aims at comparing a novel cup alignment guide, which can be attached to our anatomical pelvic plane (APP) pelvic lateral positioner for reducing discrepancies in sagittal pelvic tilt and indicate a targeted cup angle based on the APP, with a conventional cup alignment guide. The subjects were 136 hips of 136 patients who underwent unilateral THA using the APP positioner. The procedure was performed with the conventional cup alignment guide (conventional group; 60 hips) and with the novel cup navigator (mechanical navigator group; 76 hips). Postoperative cup angles and discrepancies of postoperative cup angles (inclination and anteversion angles) from the targeted angles were compared between the 2 groups to evaluate the usefulness of these navigators. The mean cup angles in the conventional group were 39.0° ± 5.3° for the inclination angle and 21.7° ± 6.4° for the anteversion angle, whereas those in the mechanical navigator group were 40.6° ± 3.2° and 18.3° ± 4.6°, respectively (P = .018, P < .0001). The discrepancies from the targeted angles were 3.5° ± 3.1° for the inclination angle and 4.6° ± 3.4° for the anteversion angle in the conventional group and 2.3° ± 2.3° and 3.2° ± 2.7°, respectively, in the mechanical navigator group (P = .020, P = .012). The mechanical cup navigator easily attachable to the APP positioner is a tool that can improve the accuracy of cup placement in a simple, economical, and noninvasive manner in THA via the lateral position. Copyright © 2017 Elsevier Inc. All rights reserved.
Kawase, Saya; Hannah, Beverly; Wang, Yue
2014-09-01
This study examines how visual speech information affects native judgments of the intelligibility of speech sounds produced by non-native (L2) speakers. Native Canadian English perceivers as judges perceived three English phonemic contrasts (/b-v, θ-s, l-ɹ/) produced by native Japanese speakers as well as native Canadian English speakers as controls. These stimuli were presented under audio-visual (AV, with speaker voice and face), audio-only (AO), and visual-only (VO) conditions. The results showed that, across conditions, the overall intelligibility of Japanese productions of the native (Japanese)-like phonemes (/b, s, l/) was significantly higher than the non-Japanese phonemes (/v, θ, ɹ/). In terms of visual effects, the more visually salient non-Japanese phonemes /v, θ/ were perceived as significantly more intelligible when presented in the AV compared to the AO condition, indicating enhanced intelligibility when visual speech information is available. However, the non-Japanese phoneme /ɹ/ was perceived as less intelligible in the AV compared to the AO condition. Further analysis revealed that, unlike the native English productions, the Japanese speakers produced /ɹ/ without visible lip-rounding, indicating that non-native speakers' incorrect articulatory configurations may decrease the degree of intelligibility. These results suggest that visual speech information may either positively or negatively affect L2 speech intelligibility.
Federal Register 2010, 2011, 2012, 2013, 2014
2013-06-18
... Richard L. Nagy, Unit Chief, Domestic Strategic Intelligence Unit, Office of Intelligence, Warning, Plans...' estimate of the burden of the proposed collection of information, including the validity of the methodology... number: None. Component: Intelligence Division, Drug Enforcement Administration, U.S. Department of...
What a speaker's choice of frame reveals: reference points, frame selection, and framing effects.
McKenzie, Craig R M; Nelson, Jonathan D
2003-09-01
Framing effects are well established: Listeners' preferences depend on how outcomes are described to them, or framed. Less well understood is what determines how speakers choose frames. Two experiments revealed that reference points systematically influenced speakers' choices between logically equivalent frames. For example, speakers tended to describe a 4-ounce cup filled to the 2-ounce line as half full if it was previously empty but described it as half empty if it was previously full. Similar results were found when speakers could describe the outcome of a medical treatment in terms of either mortality or survival (e.g., 25% die vs. 75% survive). Two additional experiments showed that listeners made accurate inferences about speakers' reference points on the basis of the selected frame (e.g., if a speaker described a cup as half empty, listeners inferred that the cup used to be full). Taken together, the data suggest that frames reliably convey implicit information in addition to their explicit content, which helps explain why framing effects are so robust.
Self-organized flexible leadership promotes collective intelligence in human groups
Kurvers, Ralf H. J. M.; Wolf, Max; Naguib, Marc; Krause, Jens
2015-01-01
Collective intelligence refers to the ability of groups to outperform individual decision-makers. At present, relatively little is known about the mechanisms promoting collective intelligence in natural systems. We here test a novel mechanism generating collective intelligence: self-organization according to information quality. We tested this mechanism by performing simulated predator detection experiments using human groups. By continuously tracking the personal information of all members prior to collective decisions, we found that individuals adjusted their response time during collective decisions to the accuracy of their personal information. When individuals possessed accurate personal information, they decided quickly during collective decisions providing accurate information to the other group members. By contrast, when individuals had inaccurate personal information, they waited longer, allowing them to use social information before making a decision. Individuals deciding late during collective decisions had an increased probability of changing their decision leading to increased collective accuracy. Our results thus show that groups can self-organize according to the information accuracy of their members, thereby promoting collective intelligence. Interestingly, we find that individuals flexibly acted both as leader and as follower depending on the quality of their personal information at any particular point in time. PMID:27019718
Šťastný, E; Trč, T; Frýdl, J; Kopečný, Z; Philippou, T; Lisý, J
2017-01-01
INTRODUCTION The purpose of our paper is to evaluate the mid-term to long-term results and to confirm the basic criteria of a high-quality revision implant: safe bridging of bone defects, achievement of reliable primary fixation of revision acetabular cup, achievement of good secondary stability with documentable osteointegration of cup and demonstration of remodelling of transplanted bone tissue in the area of defects and in spaces between the implant ribs. MATERIAL AND METHODS Altogether 36 patients (38 cups) were evaluated who had undergone revision hip arthroplasty in the period from 2004 to 2010. The mean follow-up was 8.2 years (5.1-11.6 years after the reimplantation, more than 10 years in 16 patients who underwent surgery). The position and osseointegration of the implant were assessed by digital radiography, the remodelling of transplanted bone tissues in the area of defects and between the implant ribs by computed tomography with reducing artefacts around the metal implant (Aquilion 64 - Toshiba Medical Systems), and for the clinical outcomes the Harris Hip Score was used. RESULTS Preoperatively, the condition of the hip joint based on the Harris Hip Score was in 30 cases evaluated as poor, in 8 patients as satisfactory. At the time of final evaluation, 8 patients achieved excellent results, in 19 patients the condition of the joint was very good (in 2 patients bilaterally), in 6 patients it was considered satisfactory and in 3 patients poor. The mean value for HHS increased from 39.5 to 84.5. Based on the radiography evaluation, in 27 patients (in 2 patients bilaterally) the osseointegration of the revision cup was good, in 8 cases with a radiolucent line of 2-4 mm in width in DeLee zone III, in one case proximal migration of the cup occurred caused by deep infection. The informed consent form for pelvic CT was signed by 25 patients of our cohort. Remodelling of bone tissue in the space between the ribs of the implant was always detected, the presence of bone cysts was not reported, the bone defects following the application of autologous spongioplasty in the monitored patients were healed. In 6 patients, an ingrowth of fibrous tissue of 2-4 mm in width in the convexity of the cup was detected. The mean survival of the revision oval-shaped cup - TC type with a follow-up of 8.2 years after the reimplantation based on Kaplan-Meier analysis was 91.4 %. DISCUSSION The number of revision total hip arthroplasties due to a younger age of patients who undergo alloplasty keeps growing. The choice of a revision implant should always match the intraoperative finding and the bone tissue quality. The standard uncemented implants with osteoactive surface can be opted for when anterior and posterior column of the acetabulum are intact (IIA and IIB according to Paprosky). Starting from type IIC, also the proximal part of acetabulum shall be considered. At our department, preference is given to the revision cup - TC type. The oval shape facilitates a lower degree of bone resection and easier restoration of the anatomical centre of rotation. Careful debridement of granulating and necrotic tissue, thorough treatment of bone defects and osteoactive surface of implants in case of adequate primary fixation of the cup substantially contribute to the quality of its osseointegration. Greater rigidity of fixation verified by pull-out tests enables to insert angular stable screws into the gaps in the proximal part of the cup. There is still room for improvement in treating the bone defect. The application of allogenic bone grafts into the defects and spaces between the ribs of the TC cup is more challenging than the use of augmentation in the systems with trabecular titanium. Based on the evaluation of CT scans, remodelling of the transplanted bone occurs, therefore the defect zone is reduced. CONCLUSIONS The oval-shaped uncemented cup - type TC meets the requirements placed on a state-of the art revision implant, moreover its specific construction helps improve the conditions where another re-operation of acetabulum is necessary. By evaluating mid-term to long-term results of non-homogenous group of 36 patients (38 cups) we have obtained data on joint function comparable to similar groups with revision uncemented implants presented in our and foreign literature. Key words: revision oval-shaped cup, bone remodelling, pull-out tests, angular stable screws, computed tomography.
2011-06-22
accessible by intelligence professionals and intelligence organizations frequently do not dedicate enough effort to support the process of...In every theater, Commanders have developed non-doctrinal organizations uniquely suited to their mission in an effort to integrate socio-cultural...information into military decision-making processes. A prime example of a non-traditional organization is the Stability Operations Information
Schueller, Stephen M
2016-01-01
Background Perinatal depression and anxiety are common and debilitating conditions. Novel, cost effective services could improve the uptake and the impact of mental health resources among women who suffer from these conditions. E-mental health products are one example of such services. Many publically available e-mental health products exist, but these products lack validation and are not designed to be integrated into existing health care settings. Objective The objective of the study was to present a program to use 7 Cups of Tea (7Cups), an available technological platform that provides online peer (ie, listener) based emotional support, to supplement treatment for women experiencing perinatal depression or anxiety and to summarize patient’s feedback on the resultant program. Methods This study consisted of two stages. First, five clinicians specializing in the treatment of perinatal mood disorders received an overview of 7Cups. They provided feedback on the 7Cups platform and ways it could complement the existing treatment efforts to inform further adjustments. In the second stage, nine women with perinatal depression or anxiety used the platform for a single session and provided feedback. Results In response to clinicians’ feedback, guidelines for referring patients to use 7Cups as a supplement for treatment were created, and a training program for listeners was developed. Patients found the platform usable and useful and their attitudes toward the trained listeners were positive. Overall, patients noted a need for support outside the scheduled therapy time and believed that freely available online emotional support could help meet this need. Most patients were interested in receiving support from first time mothers and those who suffered in the past from perinatal mood disorders. Conclusions The study results highlight the use of 7Cups as a tool to introduce accessible and available support into existing treatment for women who suffer from perinatal mood disorders. Further research should focus on the benefits accrued from such a service. However, this article highlights how a publicly available eHealth product can be leveraged to create new services in a health care setting. PMID:27001373
Switching benchmarks in cancer of unknown primary: from autopsy to microarray.
Pentheroudakis, George; Golfinopoulos, Vassilios; Pavlidis, Nicholas
2007-09-01
Cancer of unknown primary (CUP) is associated with unknown biology and dismal prognosis. Information on the primary site of origin is scant and has never been analysed. We systematically reviewed all published evidence on the CUP primary site identified by two different approaches, either autopsy or microarray gene expression profiling. Published reports on identification of CUP primary site by autopsy or microarray-based multigene expression platforms were retrieved and analysed for year of publication, primary site, patient age, gender, histology, rate of primary identification, manifestations and metastatic deposits, microarray chip technology, training and validation sets, mathematical modelling, classification accuracy and number of classifying genes. From 1944 to 2000, a total of 884 CUP patients (66% males) underwent autopsy in 12 studies after presenting with metastatic or systemic symptoms and succumbing to their disease. A primary was identified in 644 (73%) of them, mostly in the lung (27%), pancreas (24%), hepatobiliary tree (8%), kidneys (8%), bowel, genital system and stomach, as a small focus of adenocarcinoma or poorly differentiated carcinoma. An unpredictable systemic dissemination was evident with high frequency of lung (46%), nodal (35%), bone (17%), brain (16%) and uncommon (18%) deposits. Between the 1944-1980 and the 1980-2000 series, female representation increased, 'undetermined neoplasm' diagnosis became rarer, pancreatic primaries were found less often while colonic ones were identified more frequently. Four studies using microarray technology profiled more than 500 CUP cases using classifier set of genes (ranging from 10 to 495) and reported strikingly dissimilar frequencies of assigned primary sites (lung 11.5%, pancreas 12.5%, bowel 12%, breast 15%, hepatobiliary tree 8%, kidneys 6%, genital system 9%, bladder 5%) in 75-90% of the cases. Evolution in medical imaging technology, diet and lifestyle habits probably account for changing epidemiology of CUP primaries in autopsies. Discrepant assignment of primary sites by microarrays may be due to the presence of 'sanctuary sites' in autopsies, molecular misclassification and the postulated presence of a pro-metastatic genetic signature. In view of the absence of patient therapeutic or prognostic benefit with primary identification, gene expression profiling should be re-orientated towards unraveling the complex pathophysiology of metastases.
33 CFR 165.T11-0551 - Safety Zone; America's Cup Sailing Events.
Code of Federal Regulations, 2013 CFR
2013-07-01
... Sailing Events. 165.T11-0551 Section 165.T11-0551 Navigation and Navigable Waters COAST GUARD, DEPARTMENT... § 165.T11-0551 Safety Zone; America's Cup Sailing Events. (a) Definitions—(1) America's Cup Racing... 34th America's Cup sailing events. (2) Patrol Commander. As used in this section, “Patrol Commander” or...
78 FR 57482 - Safety Zone; America's Cup Aerobatic Box, San Francisco Bay, San Francisco, CA
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2013-09-19
...-AA00 Safety Zone; America's Cup Aerobatic Box, San Francisco Bay, San Francisco, CA AGENCY: Coast Guard... America's Cup air shows. These safety zones are established to provide a clear area on the water for... announced by America's Cup Race Management. ADDRESSES: Documents mentioned in this preamble are part of...
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...] Special Local Regulation and Safety Zone; America's Cup Sailing Events, San Francisco, CA AGENCY: Coast... 2012 program calendar for the on-water activities associated with the ``2012 America's Cup World Series... waters of San Francisco Bay associated with the 34th America's Cup sailing events taking place adjacent...
46 CFR 30.10-27 - Flashpoint-TB/ALL.
Code of Federal Regulations, 2010 CFR
2010-10-01
... gives off a flammable vapor when heated in an open-cup tester. For the purpose of the regulations in... with an open-cup tester, as follows: Table 30.10-27—Equivalent Flashpoints [In degrees Farenheit] Open-cup tester Tag closed-cup tester (A.S.T.M.) Pensky-Martens closed tester (A.S.T.M.) 80 75 150 140 ...
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2012-08-21
...] RIN 1625-AA00; 1625-AA08 Special Local Regulation and Safety Zone; America's Cup World Series Regattas... Acronyms APA Administrative Procedure Act ACRM America's Cup Race Management DHS Department of Homeland... associated with the ``2012 America's Cup World Series'' regatta scheduled to occur August 21-26, 2012 (77 FR...
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46 CFR 30.10-27 - Flashpoint-TB/ALL.
Code of Federal Regulations, 2011 CFR
2011-10-01
... gives off a flammable vapor when heated in an open-cup tester. For the purpose of the regulations in... with an open-cup tester, as follows: Table 30.10-27—Equivalent Flashpoints [In degrees Farenheit] Open-cup tester Tag closed-cup tester (A.S.T.M.) Pensky-Martens closed tester (A.S.T.M.) 80 75 150 140 ...
77 FR 54815 - Safety Zone: America's Cup World Series Regattas, San Francisco Bay; San Francisco, CA
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2012-09-06
...-AA00 Safety Zone: America's Cup World Series Regattas, San Francisco Bay; San Francisco, CA AGENCY... the on-water activities associated with 2012 America's Cup World Series regattas scheduled for October..., the City of San Francisco plans to host two America's Cup World Series regattas as part of a circuit...
A Laboratory Study of the Effects of Diet and Bright Light Countermeasures to Jet Lag
1990-03-01
3) Dinner : 1 cup raw vegetables or 1/2 cup cooked vegetables (several vegetables were unlimited such as lettuce) 1 egg or ounce of cheese or meat...1 tbsp butter or margarine 1 fruit exchange* 1 bread or pasta exchange* 2 1/ 3 cups raw vegetables or 1 1/ 4 cups cooked 1/ 4 cup milk...Search and the Human Observer. Clare W and Sinclair MA (eds) . Taylor and Francis~ondon , ~ pp. 30-39. (18) Rechtschaffen A and Kales A. ~Manual of
Cupping regulates local immunomodulation to activate neural-endocrine-immune worknet.
Guo, Yang; Chen, Bo; Wang, Dong-Qiang; Li, Ming-Yue; Lim, Calista Hui-Min; Guo, Yi; Chen, Zelin
2017-08-01
Research on cupping therapy is lacking at home and abroad. However, cupping and acupuncture therapy are both surface stimulation therapies. This paper suggests the mechanism of cupping therapy and proposes that the same mechanism underlies both cupping and acupuncture therapy. The microenvironment is changed when stimulating the surface of the skin, and physical signals transform into biological signals, which also interact with each other in the body. These signalling cascades activate the neuroendocrine-immune system, which produces the therapeutic effect. Copyright © 2017 Elsevier Ltd. All rights reserved.
Kim, Kun Hyung; Kim, Tae-Hun; Hwangbo, Min; Yang, Gi Young
2012-09-01
A case is reported of skin pigmentation and associated anemia resulting from persistently repeated cupping therapies performed by an unqualified practitioner in South Korea. Almost 30 sessions of excessive cupping therapies with blood loss over two months yielded little benefit but led the patient to admit a hospital and receive blood transfusion for acquired iron deficiency anemia. Skin pigmentation on the cupping-attached region remained without any subjective discomfort. We suggest the importance of qualified health professionals when receiving cupping treatments.
Chu, Chang-Chi; Jackson, Charles G; Alexander, Patrick J; Karut, Kamil; Henneberry, Thomas J
2003-06-01
Equipping the standard plastic cup trap, also known as the CC trap, with lime-green light-emitting diodes (LED-plastic cup trap) increased its efficacy for catching Bemisia tabaci by 100%. Few Eretmocerus eremicus Rose and Zolnerowich and Encarsia formosa Gahan were caught in LED-plastic cup traps. The LED-plastic cup traps are less expensive than yellow sticky card traps for monitoring adult whiteflies in greenhouse crop production systems and are more compatible with whitefly parasitoids releases for Bemisia nymph control.
Deng, Xiao-Lan; Chen, Bo; Chen, Ze-Lin
2014-12-01
The diagnostic evidence on clinical diseases and theoretic basis of moving cupping therapy were ex- plored in the paper. By the observation of the local reaction, such as skin appearance and color, the affected location, duration of sickness and nature of disease were judged. Different moving cupping methods were selected for different disorders. It was discovered that the property of syndromes should be recognized by the palpation on skin and muscle in the moving cupping therapy so that the pathogenesis and treating principle could be carefully determined. The moving cupping therapy is the important component of body surface therapy. Skin reaction observation and syndrome differentiation is the essential guidance of the moving cupping therapy.
ERIC Educational Resources Information Center
Gilbert, George L., Ed.
1985-01-01
Describes two demonstrations that require almost no preparation time, are visually stimulating, and present a variety of material for class discussion (with sample questions provided). The first involves a sodium bicarbonate hydrochloric acid volcano; the second involves a dissolving polystyrene cup. Procedures used and information on…
Heising, Jenneke K; Claassen, G D H; Dekker, Matthijs
2017-10-01
Optimising supply chain management can help to reduce food waste. This paper describes how intelligent packaging can be used to reduce food waste when used in supply chain management based on quality-controlled logistics (QCL). Intelligent packaging senses compounds in the package that correlate with the critical quality attribute of a food product. The information on the quality of each individual packaged food item that is provided by the intelligent packaging can be used for QCL. In a conceptual approach it is explained that monitoring food quality by intelligent packaging sensors makes it possible to obtain information about the variation in the quality of foods and to use a dynamic expiration date (IP-DED) on a food package. The conceptual approach is supported by quantitative data from simulations on the effect of using the information of intelligent packaging in supply chain management with the goal to reduce food waste. This simulation shows that by using the information on the quality of products that is provided by intelligent packaging, QCL can substantially reduce food waste. When QCL is combined with dynamic pricing based on the predicted expiry dates, a further waste reduction is envisaged.
A Study of Security Awareness Information Delivery within the Defense Intelligence Community
ERIC Educational Resources Information Center
Krasley, Paul F.
2011-01-01
Due to limited resources and inconsistent guidance from the U.S. Federal Government, Department of Defense, and multiple environments within the intelligence community, the defense intelligence agencies each developed their own methods to deliver security awareness information. These multiple delivery methods may be providing different levels of…
Expertise, Task Complexity, and Artificial Intelligence: A Conceptual Framework.
ERIC Educational Resources Information Center
Buckland, Michael K.; Florian, Doris
1991-01-01
Examines the relationship between users' expertise, task complexity of information system use, and artificial intelligence to provide the basis for a conceptual framework for considering the role that artificial intelligence might play in information systems. Cognitive and conceptual models are discussed, and cost effectiveness is considered. (27…
77 FR 26258 - Privacy Act of 1974; System of Records
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2012-05-03
...; System of Records AGENCY: Defense Intelligence Agency, DoD. ACTION: Notice to Alter a System of Records. SUMMARY: The Defense Intelligence Agency is proposing to alter a system to its existing inventory of... identifiers or contact information. FOR FURTHER INFORMATION CONTACT: Ms. Theresa Lowery, Defense Intelligence...
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... DEPARTMENT OF JUSTICE National Drug Intelligence Center [OMB Number 1105-0087] Agency Information... of Justice (DOJ), National Drug Intelligence Center (NDIC), will be submitting the following... technicians, medical examiners); and other specific groups such as drug intelligence analysts. The NDIC has...
77 FR 57077 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2012-09-17
...; System of Records AGENCY: Defense Intelligence Agency, DoD. ACTION: Notice to Add a System of Records. SUMMARY: The Defense Intelligence Agency is proposing the add a system to its existing inventory of... information. FOR FURTHER INFORMATION CONTACT: Ms. Theresa Lowery at Defense Intelligence Agency, DAN 1-C, 600...
NASA Technical Reports Server (NTRS)
Lum, Henry, Jr.
1988-01-01
Information on systems autonomy is given in viewgraph form. Information is given on space systems integration, intelligent autonomous systems, automated systems for in-flight mission operations, the Systems Autonomy Demonstration Project on the Space Station Thermal Control System, the architecture of an autonomous intelligent system, artificial intelligence research issues, machine learning, and real-time image processing.
ERIC Educational Resources Information Center
Hendon, Michalina
2016-01-01
This quantitative non-experimental correlational research analyzes the relationship between emotional intelligence and communication due to the lack of this research on information technology professionals in the U.S. One hundred and eleven (111) participants completed a survey that measures both the emotional intelligence and communication…
ERIC Educational Resources Information Center
Dou, Henri
2000-01-01
Presents several aspects of the development of actionable competitive intelligence into SMEs (small and medium enterprises). Describes types of information used in SMEs, economic intelligence in France, suggestions for information management, and various works undertaken through the European Community. (Contains 11 references.) (Author/LRW)
28 CFR 16.74 - Exemption of National Security Division Systems-limited access.
Code of Federal Regulations, 2013 CFR
2013-07-01
... Privacy Act pursuant to 5 U.S.C. 552a(j)(2), (k)(1), (2) and (5): Foreign Intelligence and... concerning him or her would hinder authorized United States intelligence activities by informing that...) Subsection (d)(1). Disclosure of foreign intelligence and counterintelligence information would interfere...
28 CFR 16.74 - Exemption of National Security Division Systems-limited access.
Code of Federal Regulations, 2012 CFR
2012-07-01
... Privacy Act pursuant to 5 U.S.C. 552a(j)(2), (k)(1), (2) and (5): Foreign Intelligence and... concerning him or her would hinder authorized United States intelligence activities by informing that...) Subsection (d)(1). Disclosure of foreign intelligence and counterintelligence information would interfere...
28 CFR 16.74 - Exemption of National Security Division Systems-limited access.
Code of Federal Regulations, 2014 CFR
2014-07-01
... Privacy Act pursuant to 5 U.S.C. 552a(j)(2), (k)(1), (2) and (5): Foreign Intelligence and... concerning him or her would hinder authorized United States intelligence activities by informing that...) Subsection (d)(1). Disclosure of foreign intelligence and counterintelligence information would interfere...
28 CFR 16.74 - Exemption of National Security Division Systems-limited access.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Privacy Act pursuant to 5 U.S.C. 552a(j)(2), (k)(1), (2) and (5): Foreign Intelligence and... concerning him or her would hinder authorized United States intelligence activities by informing that...) Subsection (d)(1). Disclosure of foreign intelligence and counterintelligence information would interfere...
2012-12-01
flows, diversity, emergence, networks, fusion, strategic planning, information sharing, ecosystem, hierarchy, NJ Regional Operations Intelligence ...Related Information...........................................................................79 viii 3. Production of Disaster Intelligence for... Intelligence for Field Personnel .................80 5. Focused Collection Efforts to Support FEMA and NJ OEM Operations
Partial Bibliography of Work on Expert Systems,
1982-12-01
Bibliography: AAAI American Association for Artificial Intelligence ACM Association for Computing Machinery AFIPS American Federation of Information...Processing Societies ECAI European Conference on Artificial Intelligence IEEE Institute for Electrical and Electronic Engineers IFIPS International...Federation of Information Processing Societies IJCAI International Joint Conferences on Artificial Intelligence SIGPLAN ACM Special Interest Group on
1990-12-01
data rate to the electronics would be much lower on the average and the data much "richer" in information. Intelligent use of...system bottleneck, a high data rate should be provided by I/O systems. 2. machines with intelligent storage management specially designed for logic...management information processing, surveillance sensors, intelligence data collection and handling, solid state sciences, electromagnetics, and propagation, and electronic reliability/maintainability and compatibility.
Human/autonomy collaboration for the automated generation of intelligence products
NASA Astrophysics Data System (ADS)
DiBona, Phil; Schlachter, Jason; Kuter, Ugur; Goldman, Robert
2017-05-01
Intelligence Analysis remains a manual process despite trends toward autonomy in information processing. Analysts need agile decision--support tools that can adapt to the evolving information needs of the mission, allowing the analyst to pose novel analytic questions. Our research enables the analysts to only provide a constrained English specification of what the intelligence product should be. Using HTN planning, the autonomy discovers, decides, and generates a workflow of algorithms to create the intelligence product. Therefore, the analyst can quickly and naturally communicate to the autonomy what information product is needed, rather than how to create it.
Intelligent Agents: Information Strategies for the Information Society.
ERIC Educational Resources Information Center
Garcia-Sierra, A. J.
In the workplace of today which is increasingly being overloaded with information, the concept of intelligent information agents has been widely prescribed. This paper briefly looks at the United Kingdom Government's Information Society Initiative which has been fueled by the realization that information is the key component of the ongoing…
Al Jaouni, Soad K; El-Fiky, Eman A; Mourad, Samiha A; Ibrahim, Nahla Khamis; Kaki, Abdullah M; Rohaiem, Sawsan M; Qari, Mohamad H; Tabsh, Laila M; Aljawhari, Adel A
2017-01-01
To assess the effect of wet cupping on health-related quality of life (HRQOL) of adult patients with chronic medical conditions, who were referred to the Cupping Clinic of King Abdulaziz University Hospital (KAUH), Jeddah, Kingdom of Saudi Arabia. Methods: A controlled, quasi-experimental study design was carried out among 629 patients referred for cupping from the KAUH Specialty Clinics, during the period from January to December 2014. Patients in the intervention group (309 patients) completed a pre-test included WHO quality of life-BREF, received one wet-cupping session, and filled-out the post-test (1 month later). Patients in the control group (320 patients) completed the pre-test during their enrollment in the study and post-test one month later. Both groups received their ordinary treatment. Descriptive and inferential statistics were performed. Results: Pain was the most common cause for cupping referral. After cupping intervention, the mean scores of most of the HRQOL domains, especially the physical domain, improved significantly among patients in the intervention group. The mean total score of physical HRQOL domain was 61.6 ± 13.6 before cupping, and reached 69.7 ± 12.6 after intervention (paired t-test=11.3, p=0.000). Improvements in HRQOL were noticed for almost all types of pain and other medical conditions. Conclusion: There are promising effects in favor of using wet cupping for improving HRQOL of patients with chronic conditions. Cupping is recommended as a complementary treatment modality for chronic medical conditions, especially pain.
Amirouche, Farid; Solitro, Giovanni F; Walia, Amit; Gonzalez, Mark; Bobko, Aimee
2017-08-01
Management of segmental rim defects and bone mineral density (BMD) loss in the elderly prior to total hip replacement is unclear within classification systems for acetabular bone loss. In this study, our objectives were (1) to understand how a reduction in BMD in the elderly affects the oversizing of a press-fit cup for primary fixation and (2) to evaluate whether the location of the segmental defect affected cup fixation. A finite element (FE) model was used to simulate and evaluate cup insertion and fixation in the context of segmental rim defects. We focused on the distribution of patients over age 70 and used BMD (estimated from CT) as a proxy for aging's implications on THR and used probabilistic FE analysis to understand how BMD loss affects oversizing of a press-fit cup. A cup oversized by 1.10 ± 0.28 mm provides sufficient fixation and lower stresses at the cup-bone interface for elderly patients. Defects in the anterior column and posterior column both required the same mean insertion force for cup seating of 84% (taken as an average of 2 anterior column and 2 posterior column defects) compared to the control configuration, which was 5% greater than the insertion force for a superior rim defect and 12% greater than the insertion force for an inferior rim defect. A defect along the superior or inferior rim had a minimal effect on cup fixation, while a defect in the columns created cup instability and increased stress at the defect location.
Nonfoux, Louis; Chiaruzzi, Myriam; Badiou, Cédric; Baude, Jessica; Tristan, Anne; Thioulouse, Jean; Muller, Daniel; Prigent Combaret, Claire; Lina, Gérard
2018-04-20
Fifteen currently marketed intravaginal protection products (11 types of tampon and four menstrual cups) were tested by the modified tampon sac method to determine their effect on Staphylococcus aureus growth and toxic shock toxin 1 (TSST-1) production. Most tampons reduced S. aureus growth and TSST-1 production, with differences based on brand and composition, and S. aureus growth was higher in de-structured than in unaltered tampons. We observed higher S. aureus growth and toxin production in menstrual cups than in tampons, potentially due to the additional air introduced to the bag by cups, with differences based on cup composition and size. Importance Menstrual toxic shock syndrome is a rare but severe disease. It occurs in healthy women vaginally colonized by Staphylococcus aureus producing toxic shock syndrome toxin 1 using intravaginal protection such as tampons or menstrual cups. Intravaginal protection induces TSS production by collecting catamenial products which act as a growth medium for S. aureus Previous studies have evaluated the impact of tampon composition on S. aureus producing toxic shock syndrome toxin 1, but they are not recent and did not include menstrual cups. This study demonstrates that highly reproducible results for S. aureus growth and TSST-1 production can be obtained using a simple protocol that reproduces the physiological conditions of tampon and cup usage as closely as possible, providing recommendations for tampon or cup use to both manufacturers and consumers. Notably, our results do not show that menstrual cups are safer than tampons and suggest that they require similar precautions. Copyright © 2018 American Society for Microbiology.
Jaouni, Soad K. Al; El-Fiky, Eman A.; Mourad, Samiha A.; Ibrahim, Nahla Khamis; Kaki, Abdullah M.; Rohaiem, Sawsan M.; Qari, Mohamad H.; Tabsh, Laila M.; Aljawhari, Adel A.
2017-01-01
Objectives: To assess the effect of wet cupping on health-related quality of life (HRQOL) of adult patients with chronic medical conditions, who were referred to the Cupping Clinic of King Abdulaziz University Hospital (KAUH), Jeddah, Kingdom of Saudi Arabia. Methods: A controlled, quasi-experimental study design was carried out among 629 patients referred for cupping from the KAUH Specialty Clinics, during the period from January to December 2014. Patients in the intervention group (309 patients) completed a pre-test included WHO quality of life-BREF, received one wet-cupping session, and filled-out the post-test (1 month later). Patients in the control group (320 patients) completed the pre-test during their enrollment in the study and post-test one month later. Both groups received their ordinary treatment. Descriptive and inferential statistics were performed. Results: Pain was the most common cause for cupping referral. After cupping intervention, the mean scores of most of the HRQOL domains, especially the physical domain, improved significantly among patients in the intervention group. The mean total score of physical HRQOL domain was 61.6 ± 13.6 before cupping, and reached 69.7 ± 12.6 after intervention (paired t-test=11.3, p=0.000). Improvements in HRQOL were noticed for almost all types of pain and other medical conditions. Conclusion: There are promising effects in favor of using wet cupping for improving HRQOL of patients with chronic conditions. Cupping is recommended as a complementary treatment modality for chronic medical conditions, especially pain. PMID:28042631
Vacuum delivery at The Maternity Hospital Kuala Lumpur: a comparison of metal and silicone cups.
Lee, H Y; Subramaniam, N; Nordin, M M
1996-02-01
To compare the advantages and disadvantages of the New Bird metal cups and silicone cups in terms of maternal and foetal outcome. To study the adverse effects and factors associated with failed vacuum deliveries. A prospective randomised study of all vacuum deliveries from 1 December 1991 to 31 April 1992. The Hanshin electrical vacuum pump was used. A large obstetric unit-The Maternity Hospital Kuala Lumpur (MHKL). Seventy-two consecutive patients where vacuum deliveries were indicated. Forty had metal and 32 had silicone cups. Another 7 vacuum deliveries using the manual vacuum pump were excluded. Success rate of vaginal delivery, birth canal injuries, post-partum haemorrhage, duration of hospital stay, Apgar score, foetal injuries (scalp-ecchymosis, haematomas) neonatal jaundice, the rate of special care nursery (SCN) admission and neonatal mortality rate. Failure to deliver with silicone cups alone was 21.9% compared to 10% for metal cups alone. Material morbidities and serious foetal scalp injuries were almost the same in both cups. However, minor foetal scalp injuries were significantly lower with silicone cups. Maternal height and baby's weight had no independent predictive values for successful vacuum delivery. When the foetal head was palpable per abdomen, the failure rate was 54.5% compared to 8.2% when it was not. Failed vacuum deliveries were associated with increased maternal and foetal morbidities. Silicone cups and metal cups can be equally dangerous to the baby. Although our sample size was small, we recommend that vacuum delivery be avoided if the foetal head is palpable per abdomen.
The translational regulator Cup controls NMJ presynaptic terminal morphology.
Menon, Kaushiki P; Carrillo, Robert A; Zinn, Kai
2015-07-01
During oogenesis and early embryonic development in Drosophila, translation of proteins from maternally deposited mRNAs is tightly controlled. We and others have previously shown that translational regulatory proteins that function during oogenesis also have essential roles in the nervous system. Here we examine the role of Cup in neuromuscular system development. Maternal Cup controls translation of localized mRNAs encoding the Oskar and Nanos proteins and binds to the general translation initiation factor eIF4E. In this paper, we show that zygotic Cup protein is localized to presynaptic terminals at larval neuromuscular junctions (NMJs). cup mutant NMJs have strong phenotypes characterized by the presence of small clustered boutons called satellite boutons. They also exhibit an increase in the frequency of spontaneous glutamate release events (mEPSPs). Reduction of eIF4E expression synergizes with partial loss of Cup expression to produce satellite bouton phenotypes. The presence of satellite boutons is often associated with increases in retrograde bone morphogenetic protein (BMP) signaling, and we show that synaptic BMP signaling is elevated in cup mutants. cup genetically interacts with two genes, EndoA and Dap160, that encode proteins involved in endocytosis that are also neuronal modulators of the BMP pathway. Endophilin protein, encoded by the EndoA gene, is downregulated in a cup mutant. Our results are consistent with a model in which Cup and eIF4E work together to ensure efficient localization and translation of endocytosis proteins in motor neurons and control the strength of the retrograde BMP signal. Copyright © 2015 Elsevier Inc. All rights reserved.
The translational regulator Cup controls NMJ presynaptic terminal morphology
Menon, Kaushiki P.; Carrillo, Robert A.; Zinn, Kai
2015-01-01
During oogenesis and early embryonic development in Drosophila, translation of proteins from maternally deposited mRNAs is tightly controlled. We and others have previously shown that translational regulatory proteins that function during oogenesis also have essential roles in the nervous system. Here we examine the role of Cup in neuromuscular system development. Maternal Cup controls translation of localized mRNAs encoding the Oskar and Nanos proteins and binds to the general translation initiation factor eIF4E. In this paper, we show that zygotic Cup protein is localized to presynaptic terminals at larval neuromuscular junctions (NMJs). cup mutant NMJs have strong phenotypes characterized by the presence of small clustered boutons called satellite boutons. They also exhibit an increase in the frequency of spontaneous glutamate release events (mEPSPs). Reduction of eIF4E expression synergizes with partial loss of Cup expression to produce satellite bouton phenotypes. The presence of satellite boutons is often associated with increases in retrograde bone morphogenetic protein (BMP) signaling, and we show that synaptic BMP signaling is elevated in cup mutants. cup genetically interacts with four genes (EndoA, WASp, Dap160, and Synj) encoding proteins involved in endocytosis that are also neuronal modulators of the BMP pathway. Endophilin protein, encoded by the EndoA gene, is downregulated in a cup mutant. Our results are consistent with a model in which Cup and eIF4E work together to ensure efficient localization and translation of endocytosis proteins in motor neurons and control the strength of the retrograde BMP signal. PMID:26102195
Chronological changes in functional cup position at 10 years after total hip arthroplasty.
Okanoue, Yusuke; Ikeuchi, Masahiko; Takaya, Shogo; Izumi, Masashi; Aso, Koji; Kawakami, Teruhiko
2017-09-19
This study aims to clarify the chronological changes in functional cup position at a minimum follow-up of 10 years after total hip arthroplasty (THA), and to identify the risk factors influencing a significant difference in functional cup position during the postoperative follow-up period. We evaluated the chronological changes in functional cup position at a minimum follow-up of 10 years after THA in 58 patients with unilateral hip osteoarthritis. Radiographic cup position was measured on anteroposterior pelvic radiographs with the patient in the supine position, whereas functional cup position was recorded in the standing position. Radiographs were obtained before, 3 weeks after, and every 1 year after surgery. Functional cup anteversion (F-Ant) increased over time, and was found to have significantly increased at final follow-up compared to that at 3 weeks after surgery (p<0.01). The maximum postoperative change in F-Ant was 17.0° anteriorly; 12 cases (21%) showed a postoperative change in F-Ant by >10° anteriorly. Preoperative posterior pelvic tilt in the standing position and vertebral fractures after THA were significant predictors of increasing functional cup anteversion. Although chronological changes in functional cup position do occur after THA, their magnitude is relatively low. However, posterior impingement is likely to occur, which may cause edge loading, wear of the polyethylene liner, and anterior dislocation of the hip. We believe that, for the combined anteversion technique, the safe zone should probably be 5°-10° narrower in patients predicted to show considerable changes in functional cup position compared with standard cases.
Dual Mobility Cemented Cups Have Low Dislocation Rates in THA Revisions
Langlais, Frantz L.; Gaucher, François; Musset, Thierry; Chaix, Olivier
2008-01-01
THA revisions using standard cups are at risk of dislocation (5.1% to 14.4% incidence), especially in patients over 70 years of age. Constrained tripolar cups have reduced this risk (6% incidence) but are associated with substantial loosening rates (9%). The nonconstrained dual mobility cup was designed to improve prosthetic stability (polyethylene head ≥ 40 mm diameter) without increasing loosening rates by reducing wear and limiting impingement (rotation range of 108°). We implanted 88 cemented dual mobility cups for THA revisions in 82 patients at high risk of dislocation. Average patient age was 72 years (range, 65–86 years). Eighty-five of the 88 hips were reviewed at 2 to 5 years followup. One patient (1.1%) had a traumatic dislocation at 2 years postoperatively. Two patients (2.3%) had asymptomatic early loosening and three patients (3.5%) had localized radiographic lucencies. These results confirm those with press-fit dual mobility cups suggesting a low dislocation rate at 5 years and a cup survival of 94.6%. At middle term followup, cemented dual mobility cup achieved better results than constrained cups in cases at risk of dislocation and recurrent loosening. Level of Evidence: Level IV, therapeutic study. See the Guidelines for Authors for a complete description of levels of evidence. PMID:18196422
Contact of dual mobility implants: effects of cup wear and inclination.
Uddin, M S
2015-01-01
Cup wear and inclination on the pelvic bone are significant factors, which change the contact of the articulating surfaces, thus, impacting the long-term performance of hip implants. This paper presents a finite element (FE) analysis of the contact of the dual mobility implants under the influence of cup wear and inclination. A 3D FE model of the implant was developed with the application of equivalent physiological loading and boundary conditions. Effects of cup inclination angle ranging from 45° to 60° and the wear depth ranging from 0 to 2.46 mm equivalent to up to 30 years of the implant's life on the contact pressure and von Mises stress were investigated. Simulation results show that the contact pressure and von Mises stress decrease significantly with a modest wear depth and remains quite in-sensitive to the cup inclination angle and wear depth up to 1.64 mm. With wear depth further up to 2.46 mm, the cup thickness (i.e. cup thinning on worn region) may be more predominant than increasing of contact area between the cup and the head. The wear on the inner surface of the cup is found to rule out the overall contact pressure and stress in the implant. Furthermore, individual and combined effects of both important parameters are analysed and discussed with respect to available clinical/laboratory studies.
Wang, Shaorui; Salamova, Amina; Hites, Ronald A; Venier, Marta
2018-06-05
The authors analyzed spatial and seasonal variations of current use pesticides (CUPs) levels in the atmospheric particulate phase in the Great Lakes basin. Twenty-four hour air samples were collected at six sites (two urban, two rural, and two remote) in 2015. The concentrations of 15 CUPs, including nine pyrethroid insecticides, four herbicides, one organophosphate insecticide, and one fungicide, were measured. The total CUPs concentrations were higher at the urban sites (0.38-1760 pg/m 3 ) than at the rural and remote sites (0.07-530 pg/m 3 ). The most abundant CUPs were pyrethroid insecticides at the urban sites. The levels of the other CUPs did not vary much among the six sites, except at the most remote site at Eagle Harbor, where the levels were significantly lower. Chlorothalonil was the most frequently detected CUP, which was detected in more than 76% of the samples. The atmospheric concentrations of total pyrethroid insecticides and total herbicides were correlated with local human population and developed land use. Significantly higher concentrations of most CUPs were observed in the warmer months than in the colder months at all sites. In addition to agricultural applications, which occur during the warmer months, the CUPs atmospheric concentrations may also be influenced by nonagricultural activities and the urban development.
Hu, Jing; Rovey, Joshua L
2011-07-01
A movable Faraday cup design with simple structure and adjustable impedance is described in this work. This Faraday cup has external adjustable shunt resistance for self-biased measurement setup and 50 Ω characteristic impedance to match with 50 Ω standard BNC coaxial cable and vacuum feedthroughs for nanosecond-level pulse signal measurements. Adjustable shunt resistance allows self-biased measurements to be quickly acquired to determine the electron energy distribution function. The performance of the Faraday cup is validated by tests of response time and amplitude of output signal. When compared with a reference source, the percent difference of the Faraday cup signal fall time is less than 10% for fall times greater than 10 ns. The percent difference of the Faraday cup signal pulse width is below 6.7% for pulse widths greater than 10 ns. A pseudospark-generated electron beam is used to compare the amplitude of the Faraday cup signal with a calibrated F-70 commercial current transformer. The error of the Faraday cup output amplitude is below 10% for the 4-14 kV tested pseudospark voltages. The main benefit of this Faraday cup is demonstrated by adjusting the external shunt resistance and performing the self-biased method for obtaining the electron energy distribution function. Results from a 4 kV pseudospark discharge indicate a "double-humped" energy distribution.
ERIC Educational Resources Information Center
Bergeron, Pierrette; Hiller, Christine A.
2002-01-01
Reviews the evolution of competitive intelligence since 1994, including terminology and definitions and analytical techniques. Addresses the issue of ethics; explores how information technology supports the competitive intelligence process; and discusses education and training opportunities for competitive intelligence, including core competencies…
Federal Register 2010, 2011, 2012, 2013, 2014
2010-05-28
...-AA08 Special Local Regulation for Marine Event; 2010 International Cup Regatta, Pasquotank River... traffic in a portion of the Pasquotank River, near Elizabeth City, NC, during the 2010 International Cup... event in 33 CFR 100.501 and 33 CFR Table to Sec. 100.501, No. 54. On June 5 and 6, 2010, Carolina Cup...
The Cup'ik People of the Western Tundra: A Curriculum.
ERIC Educational Resources Information Center
Pingayak, John
The Cup'ik people are a group of Yup'ik Eskimos who live in southwest Alaska. This curriculum aims to enhance Cup'ik students' interest in their own culture by making that culture a part of their daily activities; to teach students to practice the traditional Cup'ik respect for elders, fellow students, and others in the community; and to teach…
Semantics versus Statistics in the Retreat from Locative Overgeneralization Errors
ERIC Educational Resources Information Center
Ambridge, Ben; Pine, Julian M.; Rowland, Caroline F.
2012-01-01
The present study investigated how children learn that some verbs may appear in the figure-locative but not the ground-locative construction (e.g., "Lisa poured water into the cup"; "*Lisa poured the cup with water"), with some showing the opposite pattern (e.g., "*Bart filled water into the cup"; "Bart filled the cup with water"), and others…
ION PRODUCING MECHANISM (CHARGE CUPS)
Brobeck, W.W.
1959-04-21
The problems of confining a charge material in a calutron and uniformly distributing heat to the charge is described. The charge is held in a cup of thermally conductive material removably disposed within the charge chamber of the ion source block. A central thermally conducting stem is incorporated within the cup for conducting heat to the central portion of the charge contained within the cup.
Code of Federal Regulations, 2010 CFR
2010-01-01
... flammable materials by Tagliabue open-cup apparatus. 1500.43 Section 1500.43 Commercial Practices CONSUMER... materials by Tagliabue open-cup apparatus. Scope 1. (a) This method describes a test procedure for the..., that is, ignite but not continue to burn. Apparatus 3. The Tag open-cup tester is illustrated in Fig. 1...
Code of Federal Regulations, 2011 CFR
2011-01-01
... flammable materials by Tagliabue open-cup apparatus. 1500.43 Section 1500.43 Commercial Practices CONSUMER... materials by Tagliabue open-cup apparatus. Scope 1. (a) This method describes a test procedure for the..., that is, ignite but not continue to burn. Apparatus 3. The Tag open-cup tester is illustrated in Fig. 1...
Roentgen stereophotogrammetric analysis of metal-backed hemispherical cups without attached markers.
Valstar, E R; Spoor, C W; Nelissen, R G; Rozing, P M
1997-11-01
A method for the detection of micromotion of a metal-backed hemispherical acetabular cup is presented and tested. Unlike in conventional roentgen stereophotogrammetric analysis, the cup does not have to be marked with tantalum markers; the micromotion is calculated from the contours of the hemispherical part and the base circle of the cup. In this way, two rotations (tilt and anteversion) and the translations along the three cardinal axes are obtained. In a phantom study, the maximum error in the position of the cup's centre was 0.04 mm. The mean error in the orientation of the cup was 0.41 degree, with a 95% confidence interval of 0.28-0.54 degree. The in vivo accuracy was tested by repeated measurement of 21 radiographs from seven patients. The upper bound of the 95% tolerance interval for the translations along the transversal, longitudinal, and sagittal axes was 0.09, 0.07, and 0.34 mm, respectively: for the rotation, this upper bound was 0.39 degree. These results show that the new method, in which the position and orientation of metal-backed hemispherical cup is calculated from its projected contours, is a simple and accurate alternative to attaching markers to the cup.
Crosnier, Emilie A; Keogh, Patrick S; Miles, Anthony W
2016-08-01
The hip joint is subjected to cyclic loading and motion during activities of daily living and this can induce micromotions at the bone-implant interface of cementless total hip replacements. Initial stability has been identified as a crucial factor to achieve osseointegration and long-term survival. Whilst fixation of femoral stems achieves good clinical results, the fixation of acetabular components remains a challenge. In vitro methods assessing cup stability keep the hip joint in a fixed position, overlooking the effect of hip motion. The effect of hip motion on cup micromotion using a hip motion simulator replicating hip flexion-extension and a six degrees of freedom measurement system was investigated. The results show an increase in cup micromotion under dynamic hip motion compared to Static Flexion. This highlights the need to incorporate hip motion and measure all degrees of freedom when assessing cup micromotion. In addition, comparison of two press-fit acetabular cups with different surface coatings suggested similar stability between the two cups. This new method provides a basis for a more representative protocol for future pre-clinical evaluation of different cup designs. Copyright © 2016 IPEM. Published by Elsevier Ltd. All rights reserved.
Parrish, Audrey E.; Beran, Michael J.
2014-01-01
The context in which food is presented can alter quantity judgments leading to sub-optimal choice behavior. Humans often over-estimate food quantity on the basis of how food is presented. Food appears larger if plated on smaller dishes than larger dishes and liquid volumes appear larger in taller cups than shorter cups. Moreover, smaller but fuller containers are preferred in comparison to larger, but less full containers with a truly larger quantity. Here, we assessed whether similar phenomena occur in chimpanzees. Four chimpanzees chose between two amounts of food presented in different sized containers, a large (2 oz.) and small (1 oz.) cup. When different quantities were presented in the same-sized cups or when the small cup contained the larger quantity, chimpanzees were highly accurate in choosing the larger food amount. However, when different-sized cups contained the same amount of food or the smaller cup contained the smaller amount of food (but looked relatively fuller), the chimpanzees often showed a bias to select the smaller but fuller cup. These findings contribute to our understanding of how quantity estimation and portion judgment is impacted by the surrounding context in which it is presented. PMID:24374384
CUP-1 Is a Novel Protein Involved in Dietary Cholesterol Uptake in Caenorhabditis elegans
Valdes, Victor J.; Athie, Alejandro; Salinas, Laura S.; Navarro, Rosa E.; Vaca, Luis
2012-01-01
Sterols transport and distribution are essential processes in all multicellular organisms. Survival of the nematode Caenorhabditis elegans depends on dietary absorption of sterols present in the environment. However the general mechanisms associated to sterol uptake in nematodes are poorly understood. In the present work we provide evidence showing that a previously uncharacterized transmembrane protein, designated Cholesterol Uptake Protein-1 (CUP-1), is involved in dietary cholesterol uptake in C. elegans. Animals lacking CUP-1 showed hypersensitivity to cholesterol limitation and were unable to uptake cholesterol. A CUP-1-GFP fusion protein colocalized with cholesterol-rich vesicles, endosomes and lysosomes as well as the plasma membrane. Additionally, by FRET imaging, a direct interaction was found between the cholesterol analog DHE and the transmembrane “cholesterol recognition/interaction amino acid consensus” (CRAC) motif present in C. elegans CUP-1. In-silico analysis identified two mammalian homologues of CUP-1. Most interestingly, CRAC motifs are conserved in mammalian CUP-1 homologous. Our results suggest a role of CUP-1 in cholesterol uptake in C. elegans and open up the possibility for the existence of a new class of proteins involved in sterol absorption in mammals. PMID:22479487
ERIC Educational Resources Information Center
Cole, Charles; Cantero, Pablo; Sauve, Diane
1998-01-01
Outlines a prototype of an intelligent information-retrieval tool to facilitate information access for an undergraduate seeking information for a term paper. Topics include diagnosing the information need, Kuhlthau's information-search-process model, Shannon's mathematical theory of communication, and principles of uncertainty expansion and…
Li, Ting; Li, Yaoxian; Lin, Yu; Li, Kai
2016-01-01
Cupping therapy has been used in traditional Chinese medicine for thousands of years to relieve muscle pain/tendency/fatigue and to cure or reduce symbols of other diseases. However, its therapeutic effect is sparsely interpreted in the language of modern physiology. To objectively evaluate its therapeutic effect, we focused on dry cupping treatment and utilized near-infrared spectroscopy (NIRS) to assess the concentration change in oxy-hemoglobin ([HbO2]), deoxy-hemoglobin ([Hb]), and blood volume in the course of cupping therapy over 13 volunteers on the infraspinatus muscle, where is usually applied for shoulder pains. Both a prominent drop in [Hb] and a significant elevation in [HbO2] in the tissue surrounding the cupping site were observed during both cupping and post-treatment, manifesting the enhancement of oxygen uptake. This resulting promotion indicates potential positive therapeutic effect of cupping therapy in hemodynamics for facilitating muscular functions. PMID:28101413
Optic Disc and Optic Cup Segmentation Methodologies for Glaucoma Image Detection: A Survey
Almazroa, Ahmed; Burman, Ritambhar; Raahemifar, Kaamran; Lakshminarayanan, Vasudevan
2015-01-01
Glaucoma is the second leading cause of loss of vision in the world. Examining the head of optic nerve (cup-to-disc ratio) is very important for diagnosing glaucoma and for patient monitoring after diagnosis. Images of optic disc and optic cup are acquired by fundus camera as well as Optical Coherence Tomography. The optic disc and optic cup segmentation techniques are used to isolate the relevant parts of the retinal image and to calculate the cup-to-disc ratio. The main objective of this paper is to review segmentation methodologies and techniques for the disc and cup boundaries which are utilized to calculate the disc and cup geometrical parameters automatically and accurately to help the professionals in the glaucoma to have a wide view and more details about the optic nerve head structure using retinal fundus images. We provide a brief description of each technique, highlighting its classification and performance metrics. The current and future research directions are summarized and discussed. PMID:26688751
Multi-intelligence critical rating assessment of fusion techniques (MiCRAFT)
NASA Astrophysics Data System (ADS)
Blasch, Erik
2015-06-01
Assessment of multi-intelligence fusion techniques includes credibility of algorithm performance, quality of results against mission needs, and usability in a work-domain context. Situation awareness (SAW) brings together low-level information fusion (tracking and identification), high-level information fusion (threat and scenario-based assessment), and information fusion level 5 user refinement (physical, cognitive, and information tasks). To measure SAW, we discuss the SAGAT (Situational Awareness Global Assessment Technique) technique for a multi-intelligence fusion (MIF) system assessment that focuses on the advantages of MIF against single intelligence sources. Building on the NASA TLX (Task Load Index), SAGAT probes, SART (Situational Awareness Rating Technique) questionnaires, and CDM (Critical Decision Method) decision points; we highlight these tools for use in a Multi-Intelligence Critical Rating Assessment of Fusion Techniques (MiCRAFT). The focus is to measure user refinement of a situation over the information fusion quality of service (QoS) metrics: timeliness, accuracy, confidence, workload (cost), and attention (throughput). A key component of any user analysis includes correlation, association, and summarization of data; so we also seek measures of product quality and QuEST of information. Building a notion of product quality from multi-intelligence tools is typically subjective which needs to be aligned with objective machine metrics.
Aboushanab, Tamer; AlSanad, Saud
2018-06-08
Cupping therapy is a popular treatment in various countries and regions, including Saudi Arabia. Cupping therapy is regulated in Saudi Arabia by the National Center for Complementary and Alternative Medicine (NCCAM), Ministry of Health. The authors recommend that this quality model for selecting patients in cupping clinics - first version (QMSPCC-1) - be used routinely as part of clinical practice and quality management in cupping clinics. The aim of the quality model is to ensure the safety of patients and to introduce and facilitate quality and auditing processes in cupping therapy clinics. Clinical evaluation of this tool is recommended. Continued development, re-evaluation and reassessment of this tool are important. Copyright © 2018. Published by Elsevier B.V.
Web Intelligence and Artificial Intelligence in Education
ERIC Educational Resources Information Center
Devedzic, Vladan
2004-01-01
This paper surveys important aspects of Web Intelligence (WI) in the context of Artificial Intelligence in Education (AIED) research. WI explores the fundamental roles as well as practical impacts of Artificial Intelligence (AI) and advanced Information Technology (IT) on the next generation of Web-related products, systems, services, and…
Tomata, Yasutake; Kakizaki, Masako; Nakaya, Naoki; Tsuboya, Toru; Sone, Toshimasa; Kuriyama, Shinichi; Hozawa, Atsushi; Tsuji, Ichiro
2012-03-01
Previous studies have reported that green tea consumption is associated with a lower risk of diseases that cause functional disability, such as stroke, cognitive impairment, and osteoporosis. Although it is expected that green tea consumption would lower the risk of incident functional disability, this has never been investigated directly. The objective was to determine the association between green tea consumption and incident functional disability in elderly individuals. We conducted a prospective cohort study in 13,988 Japanese individuals aged ≥65 y. Information on daily green tea consumption and other lifestyle factors was collected via questionnaire in 2006. Data on functional disability were retrieved from the public Long-term Care Insurance database, in which subjects were followed up for 3 y. We used Cox proportional hazards regression analysis to investigate the association between green tea consumption and functional disability. The 3-y incidence of functional disability was 9.4% (1316 cases). The multiple-adjusted HR (95% CI) of incident functional disability was 0.90 (0.77, 1.06) among respondents who consumed 1-2 cups green tea/d, 0.75 (0.64, 0.88) for those who consumed 3-4 cups/d, and 0.67 (0.57, 0.79) for those who consumed ≥5 cups/d in comparison with those who consumed <1 cup/d (P-trend < 0.001). Green tea consumption is significantly associated with a lower risk of incident functional disability, even after adjustment for possible confounding factors.
32 CFR 1900.03 - Contact for general information and requests.
Code of Federal Regulations, 2011 CFR
2011-07-01
... INTELLIGENCE AGENCY PUBLIC ACCESS TO CIA RECORDS UNDER THE FREEDOM OF INFORMATION ACT (FOIA) General § 1900.03... communication in writing to the Information and Privacy Coordinator, Central Intelligence Agency, Washington, DC...
32 CFR 1900.03 - Contact for general information and requests.
Code of Federal Regulations, 2013 CFR
2013-07-01
... INTELLIGENCE AGENCY PUBLIC ACCESS TO CIA RECORDS UNDER THE FREEDOM OF INFORMATION ACT (FOIA) General § 1900.03... communication in writing to the Information and Privacy Coordinator, Central Intelligence Agency, Washington, DC...
Effects of Audio-Visual Information on the Intelligibility of Alaryngeal Speech
ERIC Educational Resources Information Center
Evitts, Paul M.; Portugal, Lindsay; Van Dine, Ami; Holler, Aline
2010-01-01
Background: There is minimal research on the contribution of visual information on speech intelligibility for individuals with a laryngectomy (IWL). Aims: The purpose of this project was to determine the effects of mode of presentation (audio-only, audio-visual) on alaryngeal speech intelligibility. Method: Twenty-three naive listeners were…
Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-12
... OFFICE OF THE DIRECTOR OF NATIONAL INTELLIGENCE [OMB Control No.-3440-NEW] Office of the Chief... Intelligence (ODNI). ACTION: Information Collection Activities: Proposed Collection; Comment Request--30 Day... procedures for use by the Intelligence Community agencies and elements, as defined by the National Security...
77 FR 56625 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2012-09-13
...: Ms. Theresa Lowery at Defense Intelligence Agency, DAN 1-C, 600 MacDill Blvd., Washington, DC 20340... address written inquiries to the DIA Freedom of Information Act Office (DAN-1A), Defense Intelligence... written inquiries to the DIA Freedom of Information Act Office, Defense Intelligence Agency (DAN-1A), 200...
Gas-Diverting Cup For Welding At An Angle
NASA Technical Reports Server (NTRS)
Dyer, G. E.
1988-01-01
Attachment makes automatic arc welders more versatile. Stainless-steel diverting cup slips over standard torch cup. Bent electrode inserted in torch. Assembly reaches weld joints inaccessible to straight welding torch.
ERIC Educational Resources Information Center
Bopegedera, A. M. R. P.; Perera, K. Nishanthi R.
2017-01-01
Coffee cup calorimetry, performed with calorimeters made with styrofoam coffee cups, is a familiar experiment in the general chemistry laboratory. These calorimeters are inexpensive, easy to use, and provide good insulation for most thermodynamics experiments. This paper presents the successful substitution of paper coffee cups for styrofoam cups…
Assessing Intelligence Operation/Fusion/Coordination Centers for Efficiency Opportunities
2013-02-28
intelligence ], HUMINT [human intelligence ], GEOINT [geospatial intelligence ], or even open source information into the NIC-C. There is no...centers have and continue to be stood up to improve the collaboration across intelligence organizatons addressing national security threats. Open ... source review of journals and books describing changes in the intelligence community organizational structure since September 2001, were reviewed to
Yang, Qing-Song; Yu, Ya-Jie; Li, Shu-Ning; Liu, Juan; Hao, Ying-Juan
2012-08-01
Copernicus optical coherence tomography (SOCT) is a new, ultra high-speed and high-resolution instrument available for clinical evaluation of optic nerve. The purpose of the study was to compare the agreements between SOCT and Heidelberg retinal tomography (HRT). A total of 44 healthy normal volunteers were recruited in this study. One eye in each subject was selected randomly. Agreement between SOCT and HRT-3 in measuring optic disc area was assessed using Bland-Altman plots. Relationships between measurements of optic nerve head parameter obtained by SOCT and HRT-3 were assessed by Pearson correlation. There was no significant difference in the average cup area (0.306 vs. 0.355 mm, P = 0.766), cup volume (0.158 vs. 0.130 mm, P = 0.106) and cup/disc ration (0.394 vs. 0.349 mm, P = 0.576) measured by the two instruments. However, other optic disc parameters from SOCT were significantly lower compared with HRT-3. The Bland-Altman plot revealed good agreement of cup area and cup volume measured by SOCT and HRT-3. Bad agreement of disc area, rim area, rim volume and cup/disc ratio were found between SOCT and HRT-3. The highest correlations between the two instruments were observed for cup area (r(2) = 0.783, P = 0.000) and cup/disc ratio (r(2) = 0.669, P = 0.000), whereas the lowest correlation was observed for disc area (r(2) = 0.100, P = 0.037), rim area (r(2) = 0.275, P = 0.000), cup volume (r(2) = 0.005, P = 0.391) and rim volume (r(2) = 0.021, P = 0.346). There were poor agreements between SOCT and HRT-3 for measurement of optic nerve parameters except cup area and cup volume. Measurement results of the two instruments are not interchangeable.
"TIS": An Intelligent Gateway Computer for Information and Modeling Networks. Overview.
ERIC Educational Resources Information Center
Hampel, Viktor E.; And Others
TIS (Technology Information System) is being used at the Lawrence Livermore National Laboratory (LLNL) to develop software for Intelligent Gateway Computers (IGC) suitable for the prototyping of advanced, integrated information networks. Dedicated to information management, TIS leads the user to available information resources, on TIS or…
Information management - Assessing the demand for information
NASA Technical Reports Server (NTRS)
Rogers, William H.
1991-01-01
Information demand is defined in terms of both information content (what information) and form (when, how, and where it is needed). Providing the information richness required for flight crews to be informed without overwhelming their information processing capabilities will require a great deal of automated intelligence. It is seen that the essence of this intelligence is comprehending and capturing the demand for information.
Menu Ideas for Vegetarian Teens
... 1 ounce pistachios Snack 8 ounces Greek style yogurt ¼ cup granola 1 apple 1 ounce almonds ... Jicama Salad Recipe Recipes Jicama Salad Recipe Rainbow Yogurt Trifle Cups Recipe Recipes Rainbow Yogurt Trifle Cups ...
A novel approach to determine primary stability of acetabular press-fit cups.
Weißmann, Volker; Boss, Christian; Bader, Rainer; Hansmann, Harald
2018-04-01
Today hip cups are used in a large variety of design variants and in increasing numbers of units. Their development is steadily progressing. In addition to conventional manufacturing methods for hip cups, additive methods, in particular, play an increasingly important role as development progresses. The present paper describes a modified cup model developed based on a commercially available press-fit cup (Allofit 54/JJ). The press-fit cup was designed in two variants and manufactured using selective laser melting (SLM). Variant 1 (Ti) was modeled on the Allofit cup using an adapted process technology. Variant 2 (Ti-S) was provided with a porous load bearing structure on its surface. In addition to the typical (complete) geometry, both variants were also manufactured and tested in a reduced shape where only the press-fit area was formed. To assess the primary stability of the press-fit cups in the artificial bone cavity, pull-out and lever-out tests were carried out. Exact fit conditions and two-millimeter press-fit were investigated. The closed-cell PU foam used as an artificial bone cavity was mechanically characterized to exclude any influence on the results of the investigation. The pull-out forces of the Ti-variant (complete-526 N, reduced-468 N) and the Ti-S variant (complete-548 N, reduced-526 N) as well as the lever-out moments of the Ti-variant (complete-10 Nm, reduced-9.8 Nm) and the Ti-S variant (complete-9 Nm, reduced-7.9 N) show no significant differences in the results between complete and reduced cups. The results show that the use of reduced cups in a press-fit design is possible within the scope of development work. Copyright © 2018 Elsevier Ltd. All rights reserved.
Zhao, Hong
2014-08-01
To observe the clinical effect of cupping combined with acupuncture stimulation of trigger points on lumbar myofascial pain syndrome (MPS). Sixty MPS patients were randomly divided into acupuncture + TDP group (n = 30), and cupping + acupuncture group (n = 30). Patients in the acupuncture + TDP group were treated by acupuncture stimulation of trigger points and local TDP irradiation, and patients of the cupping + acupuncture group treated by intensive cupping applied to the myofascial band and acupuncture stimulation of the locus according to the position of muscular tension band. The therapeutic effects were assessed according to the score of the McGill pain questionnaire composing of pain rating index (PRI), visual analogue scale (VAS) and present pain intensity (PPI) before, immediately and 1 month after the treatment. After the treatment, the total effective rates of the acupuncture+ TDP and cupping + acupuncture groups were 83.3% (25/30) and 96.6% (29/30), respectively, without significant difference between the two groups (P > 0.05). One month's follow-up showed that the total effective rates of the acupuncture + TDP and cupping + acupuncture groups were 40.0% and 90.0% respectively, and the latter group was significantly better than the acupuncture + TDP group in the therapeutic effect (P < 0.05). The scores of PRI, VAS, PPI after the treatment were markedly decreased in both groups (P < 0.05). One month later, the scores of PRI, VAS and PPI in the cupping + acupuncture group were obviously lower than those of the acupuncture group (P < 0.05). Both acupuncture stimulation of trigger points plus TDP and cupping plus acupuncture can effectively relieve pain in MPS patients, while the therapeutic effect of cupping plus acupuncture treatment lasts longer analgesic effect.
Löf, Marie; Sandin, Sven; Yin, Li; Adami, Hans-Olov; Weiderpass, Elisabete
2015-09-01
We investigated whether coffee consumption was associated with all-cause, cancer, or cardiovascular mortality in a prospective cohort of 49,259 Swedish women. Of the 1576 deaths that occurred in the cohort, 956 were due to cancer and 158 were due to cardiovascular disease. We used Cox proportional hazard models with adjustment for potential confounders to estimate multivariable relative risks (RR) and 95 % confidence intervals (CI). Compared to a coffee consumption of 0-1 cups/day, the RR for all cause-mortality was 0.81 (95 % CI 0.69-0.94) for 2-5 cups/day and 0.88 (95 % CI 0.74-1.05) for >5 cups/day. Coffee consumption was not associated with cancer mortality or cardiovascular mortality when analyzed in the entire cohort. However, in supplementary analyses of women over 50 years of age, the RR for all cause-mortality was 0.74 (95 % CI 0.62-0.89) for 2-5 cups/day and 0.86 (95 % CI 0.70-1.06) for >5 cups/day when compared to 0-1 cups/day. In this same subgroup, the RRs for cancer mortality were 1.06 (95 % CI 0.81-1.38) for 2-5 cups/day and 1.40 (95 % CI 1.05-1.89) for >5 cups/day when compared to 0-1 cups/day. No associations between coffee consumption and all-cause mortality, cancer mortality, or cardiovascular mortality were observed among women below 50 years of age. In conclusion, higher coffee consumption was associated with lower all-cause mortality when compared to a consumption of 0-1 cups/day. Furthermore, coffee may have differential effects on mortality before and after 50 years of age.
Gonzalez, Amanda Inez; Bartolone, Placido; Lubbeke, Anne; Dupuis Lozeron, Elise; Peter, Robin; Hoffmeyer, Pierre; Christofilopoulos, Panayiotis
2017-02-01
Background and purpose - Revision total hip arthroplasty (THA) is associated with higher dislocation rates than primary THA. We compared the risk of dislocation within 6 months and all-cause re-revision during the whole study period using either the dual-mobility cup or the unipolar cup. Methods - We used a prospective hospital registry-based cohort including all total and cup-only revision THAs performed between 2003 and 2013. The cups used were either dual-mobility or unipolar; the choice was made according to the preference of the surgeon. 316 revision THAs were included. The mean age of the cohort was 69 (25-98) years and 160 THAs (51%) were performed in women. The dual-mobility group (group 1) included 150 THAs (48%) and the mean length of follow-up was 31 (0-128) months. The unipolar group (group 2) included 166 THAs (53%) and the mean length of follow-up was 52 (0-136) months. Results - The incidence of dislocation within 6 months was significantly lower with the dual-mobility cup than with the unipolar cup (2.7% vs. 7.8%). The unadjusted risk ratio (RR) was 0.34 (95% CI: 0.11-1.02) and the adjusted RR was 0.28 (95% CI: 0.09-0.87). The number of patients needed to treat with a dual-mobility cup in order to prevent 1 case of dislocation was 19. The unadjusted incidence rate ratio for all-cause re-revision in the dual-mobility group compared to the unipolar group was 0.6 (95% CI: 0.3-1.4). Interpretation - Use of a dual-mobility rather than a unipolar cup in revision THA reduced the risk of dislocation within 6 months.
Kinkelin, Kerstin; Veith, Katharina; Grünwald, Marlene; Bono, Fulvia
2012-01-01
Cup is an eIF4E-binding protein (4E-BP) that plays a central role in translational regulation of localized mRNAs during early Drosophila development. In particular, Cup is required for repressing translation of the maternally contributed oskar, nanos, and gurken mRNAs, all of which are essential for embryonic body axis determination. Here, we present the 2.8 Å resolution crystal structure of a minimal eIF4E–Cup assembly, consisting of the interacting regions of the two proteins. In the structure, two separate segments of Cup contact two orthogonal faces of eIF4E. The eIF4E-binding consensus motif of Cup (YXXXXLΦ) binds the convex side of eIF4E similarly to the consensus of other eIF4E-binding proteins, such as 4E-BPs and eIF4G. The second, noncanonical, eIF4E-binding site of Cup binds laterally and perpendicularly to the eIF4E β-sheet. Mutations of Cup at this binding site were shown to reduce binding to eIF4E and to promote the destabilization of the associated mRNA. Comparison with the binding mode of eIF4G to eIF4E suggests that Cup and eIF4G binding would be mutually exclusive at both binding sites. This shows how a common molecular surface of eIF4E might recognize different proteins acting at different times in the same pathway. The structure provides insight into the mechanism by which Cup disrupts eIF4E–eIF4G interaction and has broader implications for understanding the role of 4E-BPs in translational regulation. PMID:22832024
Balancing Information Analysis and Decision Value: A Model to Exploit the Decision Process
2011-12-01
technical intelli- gence e.g. signals and sensors (SIGINT and MASINT), imagery (!MINT), as well and human and open source intelligence (HUMINT and OSINT ...Clark 2006). The ability to capture large amounts of da- ta and the plenitude of modem intelligence information sources provides a rich cache of...many tech- niques for managing information collected and derived from these sources , the exploitation of intelligence assets for decision-making
A situation-response model for intelligent pilot aiding
NASA Technical Reports Server (NTRS)
Schudy, Robert; Corker, Kevin
1987-01-01
An intelligent pilot aiding system needs models of the pilot information processing to provide the computational basis for successful cooperation between the pilot and the aiding system. By combining artificial intelligence concepts with the human information processing model of Rasmussen, an abstraction hierarchy of states of knowledge, processing functions, and shortcuts are developed, which is useful for characterizing the information processing both of the pilot and of the aiding system. This approach is used in the conceptual design of a real time intelligent aiding system for flight crews of transport aircraft. One promising result was the tentative identification of a particular class of information processing shortcuts, from situation characterizations to appropriate responses, as the most important reliable pathway for dealing with complex time critical situations.
NASA Technical Reports Server (NTRS)
Corey, Stephen; Carnahan, Richard S., Jr.
1990-01-01
A continuing effort to apply rapid prototyping and Artificial Intelligence techniques to problems associated with projected Space Station-era information management systems is examined. In particular, timely updating of the various databases and knowledge structures within the proposed intelligent information management system (IIMS) is critical to support decision making processes. Because of the significantly large amounts of data entering the IIMS on a daily basis, information updates will need to be automatically performed with some systems requiring that data be incorporated and made available to users within a few hours. Meeting these demands depends first, on the design and implementation of information structures that are easily modified and expanded, and second, on the incorporation of intelligent automated update techniques that will allow meaningful information relationships to be established. Potential techniques are studied for developing such an automated update capability and IIMS update requirements are examined in light of results obtained from the IIMS prototyping effort.
[The Use of Jumbo Cups in Revision Total Hip Arthroplasty].
von Roth, Philipp; Wassilew, Georgi I
2017-10-01
Extra-large uncemented jumbo cups are among the most common methods of acetabular revision. Jumbo cups do not contribute to bone stock restoration, and in the case of a subsequent revision, an even larger bone defect is to be expected. Thus, understanding long-term survival is essential. The present article discusses the literature relevant to this topic and addresses technical and implant-specific characteristics of jumbo cups. In summary, jumbo cups show an acceptable long-term survival rate, with aseptic loosening as the most common reason for revision and dislocation being the most common complication. Through the development of alternative revision systems, jumbo cups have lost their importance in today's practice. However, they can serve as a benchmark for studies of newer technologies in revision total hip arthroplasty. Georg Thieme Verlag KG Stuttgart · New York.
The current evidence for a biomarker-based approach in cancer of unknown primary.
El Rassy, Elie; Pavlidis, Nicholas
2018-05-02
Cancer of unknown primary (CUP) accounts for the seventh to eighth most frequently diagnosed cancer yet its prognosis remains poor with conventional chemotherapy. The spectrum of therapeutic management includes both locoregional and systemic therapy and should intend to offer optimal benefit to favorable CUP patients and palliative care to unfavorable cases. The recent molecular advances have revolutionized the armamentarium of cancer treatments though a biomarker-based approach. Unfortunately, solid data in CUP is lacking in the absence of a CUP-specific driver molecular signature. This prompted us to screen the medical literature for clinical data that evaluates the efficacy and safety of the biomarker-based approach in CUP patients. In this review, we will summarize the available evidence for the applicability of targeted therapies in CUP. Copyright © 2018 Elsevier Ltd. All rights reserved.
Automated detection of kinks from blood vessels for optic cup segmentation in retinal images
NASA Astrophysics Data System (ADS)
Wong, D. W. K.; Liu, J.; Lim, J. H.; Li, H.; Wong, T. Y.
2009-02-01
The accurate localization of the optic cup in retinal images is important to assess the cup to disc ratio (CDR) for glaucoma screening and management. Glaucoma is physiologically assessed by the increased excavation of the optic cup within the optic nerve head, also known as the optic disc. The CDR is thus an important indicator of risk and severity of glaucoma. In this paper, we propose a method of determining the cup boundary using non-stereographic retinal images by the automatic detection of a morphological feature within the optic disc known as kinks. Kinks are defined as the bendings of small vessels as they traverse from the disc to the cup, providing physiological validation for the cup boundary. To detect kinks, localized patches are first generated from a preliminary cup boundary obtained via level set. Features obtained using edge detection and wavelet transform are combined using a statistical approach rule to identify likely vessel edges. The kinks are then obtained automatically by analyzing the detected vessel edges for angular changes, and these kinks are subsequently used to obtain the cup boundary. A set of retinal images from the Singapore Eye Research Institute was obtained to assess the performance of the method, with each image being clinically graded for the CDR. From experiments, when kinks were used, the error on the CDR was reduced to less than 0.1 CDR units relative to the clinical CDR, which is within the intra-observer variability of 0.2 CDR units.
Effects of wet-cupping on blood pressure in hypertensive patients: a randomized controlled trial.
Aleyeidi, Nouran A; Aseri, Khaled S; Matbouli, Shadia M; Sulaiamani, Albaraa A; Kobeisy, Sumayyah A
2015-11-01
Although cupping remains a popular treatment modality worldwide, its efficacy for most diseases, including hypertension, has not been scientifically evaluated. We aimed to determine the efficacy of wet-cupping for high blood pressure, and the incidence of the procedure's side effects in the intervention group. This is a randomized controlled trial conducted in the General Practice Department at King Abdulaziz University Hospital, Jeddah, Saudi Arabia, between May 2013 and February 2014. There were two groups (40 participants each): intervention group undergoing wet-cupping (hijama) in addition to conventional hypertension treatment, and a control group undergoing only conventional hypertension treatment. Three wet-cupping sessions were performed every other day. The mean systolic and diastolic blood pressures were measured using a validated automatic sphygmomanometer. The follow-up period was 8 weeks. Wet-cupping provided an immediate reduction of systolic blood pressure. After 4 weeks of follow-up, the mean systolic blood pressure in the intervention group was 8.4 mmHg less than in the control group (P=0.046). After 8 weeks, there were no significant differences in blood pressures between the intervention and control groups. In this study, wet-cupping did not result in any serious side effects. Wet-cupping therapy is effective for reducing systolic blood pressure in hypertensive patients for up to 4 weeks, without serious side effects. Wet-cupping should be considered as a complementary hypertension treatment, and further studies are needed. ClinicalTrials.gov Identifier NCT01987583.
Köebner phenomenon induced by cupping therapy in a psoriasis patient.
Yu, Rui-Xing; Hui, Yun; Li, Cheng-Rang
2013-06-15
Psoriasis is a chronic, immune-mediated inflammatory and refractory disease. The koebner phenomenon, which can be induced by trauma, is common in psoriasis patients. Herein, we report a patient with psoriasis who was treated by cupping therapy and subsequently developed the koebner phenomenon (KP) at the cupped sites. To our knowledge, it is the first report about cupping therapy leading to KP in a psoriasis patient.
Exploring the Analytical Processes of Intelligence Analysts
DOE Office of Scientific and Technical Information (OSTI.GOV)
Chin, George; Kuchar, Olga A.; Wolf, Katherine E.
We present an observational case study in which we investigate and analyze the analytical processes of intelligence analysts. Participating analysts in the study carry out two scenarios where they organize and triage information, conduct intelligence analysis, report results, and collaborate with one another. Through a combination of artifact analyses, group interviews, and participant observations, we explore the space and boundaries in which intelligence analysts work and operate. We also assess the implications of our findings on the use and application of relevant information technologies.
[Effect of cupping on hemodynamic levels in the regional sucked tissues in patients with lumbago].
Tang, Xiao; Xiao, Xue-Hua; Zhang, Guo-Qing
2012-10-01
To observe hemodynamic changes in the local sucked tissue of lower back undergoing negative pressure after cupping in patients with lumbago. Twenty-two lumbago outpatients were recruited in the present study and 32 sucked tissues accepted measurements. The cupping was applied to the tenderpoint of the patients' lower back for 10 min by using a glass-mug (5 cm in diameter). Hemodynamic indexes [peak systolic velocity (PSV), end-diastolic velocity (EDV) and resistance index (RI)] of the sucked skin and subcutaneous tissues at the lower back were detected before and after cupping by using a color Doppler flow imaging. After cupping intervention at the lower back, the PSV [(14.2 +/- 1.8) cm/s] and EDV [(5.5 +/- 0.7) cm/s] levels were increased significantly in comparison with those [(5.9 +/- 0.9) and (1.9 +/- 0.3) cm/s] before cupping (P < 0.01), while RI was reduced evidently after cupping (0.61 +/- 0.05 vs 0.68 +/- 0.06, P < 0.01), suggesting an increase of the regional blood flow. Cupping therapy can increase the peak systolic velocity and end-diastolic velocity and lower vascular resistance of the subcutaneous arterioles in the regional tissue, which may contribute to its effect in relieving lumbago.
Optic cup segmentation: type-II fuzzy thresholding approach and blood vessel extraction
Almazroa, Ahmed; Alodhayb, Sami; Raahemifar, Kaamran; Lakshminarayanan, Vasudevan
2017-01-01
We introduce here a new technique for segmenting optic cup using two-dimensional fundus images. Cup segmentation is the most challenging part of image processing of the optic nerve head due to the complexity of its structure. Using the blood vessels to segment the cup is important. Here, we report on blood vessel extraction using first a top-hat transform and Otsu’s segmentation function to detect the curves in the blood vessels (kinks) which indicate the cup boundary. This was followed by an interval type-II fuzzy entropy procedure. Finally, the Hough transform was applied to approximate the cup boundary. The algorithm was evaluated on 550 fundus images from a large dataset, which contained three different sets of images, where the cup was manually marked by six ophthalmologists. On one side, the accuracy of the algorithm was tested on the three image sets independently. The final cup detection accuracy in terms of area and centroid was calculated to be 78.2% of 441 images. Finally, we compared the algorithm performance with manual markings done by the six ophthalmologists. The agreement was determined between the ophthalmologists as well as the algorithm. The best agreement was between ophthalmologists one, two and five in 398 of 550 images, while the algorithm agreed with them in 356 images. PMID:28515636
Optic cup segmentation: type-II fuzzy thresholding approach and blood vessel extraction.
Almazroa, Ahmed; Alodhayb, Sami; Raahemifar, Kaamran; Lakshminarayanan, Vasudevan
2017-01-01
We introduce here a new technique for segmenting optic cup using two-dimensional fundus images. Cup segmentation is the most challenging part of image processing of the optic nerve head due to the complexity of its structure. Using the blood vessels to segment the cup is important. Here, we report on blood vessel extraction using first a top-hat transform and Otsu's segmentation function to detect the curves in the blood vessels (kinks) which indicate the cup boundary. This was followed by an interval type-II fuzzy entropy procedure. Finally, the Hough transform was applied to approximate the cup boundary. The algorithm was evaluated on 550 fundus images from a large dataset, which contained three different sets of images, where the cup was manually marked by six ophthalmologists. On one side, the accuracy of the algorithm was tested on the three image sets independently. The final cup detection accuracy in terms of area and centroid was calculated to be 78.2% of 441 images. Finally, we compared the algorithm performance with manual markings done by the six ophthalmologists. The agreement was determined between the ophthalmologists as well as the algorithm. The best agreement was between ophthalmologists one, two and five in 398 of 550 images, while the algorithm agreed with them in 356 images.
Human coffee drinking: manipulation of concentration and caffeine dose.
Griffiths, R R; Bigelow, G E; Liebson, I A; O'Keeffe, M; O'Leary, D; Russ, N
1986-01-01
In a residential research ward coffee drinking was studied in 9 volunteer human subjects with histories of heavy coffee drinking. A series of five experiments was undertaken to characterize adlibitum coffee consumption and to investigate the effects of manipulating coffee concentration, caffeine dose per cup, and caffeine preloads prior to coffee drinking. Manipulations were double-blind and scheduled in randomized sequences across days. When cups of coffee were freely available, coffee drinking tended to be rather regularly spaced during the day with intercup intervals becoming progressively longer throughout the day; experimental manipulations showed that this lengthening of intercup intervals was not due to accumulating caffeine levels. Number of cups of coffee consumed was an inverted U-shaped function of both coffee concentration and caffeine dose per cup; however, coffee-concentration and dose-per-cup manipulations did not produce similar effects on other measures of coffee drinking (intercup interval, time to drink a cup, within-day distribution of cups). Caffeine preload produced dose-related decreases in number of cups consumed. As a whole, these experiments provide some limited evidence for both the suppressive and the reinforcing effects of caffeine on coffee consumption. Examination of total daily coffee and caffeine intake across experiments, however, provides no evidence for precise regulation (i.e., titration) of coffee or caffeine intake. PMID:3958660
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hu Jing; Rovey, Joshua L.
A movable Faraday cup design with simple structure and adjustable impedance is described in this work. This Faraday cup has external adjustable shunt resistance for self-biased measurement setup and 50 {Omega} characteristic impedance to match with 50 {Omega} standard BNC coaxial cable and vacuum feedthroughs for nanosecond-level pulse signal measurements. Adjustable shunt resistance allows self-biased measurements to be quickly acquired to determine the electron energy distribution function. The performance of the Faraday cup is validated by tests of response time and amplitude of output signal. When compared with a reference source, the percent difference of the Faraday cup signal fallmore » time is less than 10% for fall times greater than 10 ns. The percent difference of the Faraday cup signal pulse width is below 6.7% for pulse widths greater than 10 ns. A pseudospark-generated electron beam is used to compare the amplitude of the Faraday cup signal with a calibrated F-70 commercial current transformer. The error of the Faraday cup output amplitude is below 10% for the 4-14 kV tested pseudospark voltages. The main benefit of this Faraday cup is demonstrated by adjusting the external shunt resistance and performing the self-biased method for obtaining the electron energy distribution function. Results from a 4 kV pseudospark discharge indicate a ''double-humped'' energy distribution.« less
Federal Register 2010, 2011, 2012, 2013, 2014
2012-10-12
... DEPARTMENT OF DEFENSE Office of the Secretary Federal Advisory Committee; Defense Intelligence.... The meeting necessarily includes discussions of classified information relating to DIA's intelligence... support of current intelligence operations. Agenda October 29, 2012: [[Page 62223
Competitive Intelligence and Social Advantage.
ERIC Educational Resources Information Center
Davenport, Elisabeth; Cronin, Blaise
1994-01-01
Presents an overview of issues concerning civilian competitive intelligence (CI). Topics discussed include competitive advantage in academic and research environments; public domain information and libraries; covert and overt competitive intelligence; data diversity; use of the Internet; cooperative intelligence; and implications for library and…
ERIC Educational Resources Information Center
Thornburg, David D.
1986-01-01
Overview of the artificial intelligence (AI) field provides a definition; discusses past research and areas of future research; describes the design, functions, and capabilities of expert systems and the "Turing Test" for machine intelligence; and lists additional sources for information on artificial intelligence. Languages of AI are…
77 FR 43814 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2012-07-26
... Intelligence Agency, DAN 1-C, 600 MacDill Blvd., Washington, DC 20340- 0001 or by phone at (202) 231-1193... Freedom of Information Act Office (DAN-1A), Defense Intelligence Agency, 200 MacDill Blvd., Washington, DC... Information Act Office, Defense Intelligence Agency (DAN-1A), 200 MacDill Blvd., Washington, DC 20340-0001...
NASA Astrophysics Data System (ADS)
Qiu, Feng; Dai, Guang; Zhang, Ying
According to the acoustic emission information and the appearance inspection information of tank bottom online testing, the external factors associated with tank bottom corrosion status are confirmed. Applying artificial neural network intelligent evaluation method, three tank bottom corrosion status evaluation models based on appearance inspection information, acoustic emission information, and online testing information are established. Comparing with the result of acoustic emission online testing through the evaluation of test sample, the accuracy of the evaluation model based on online testing information is 94 %. The evaluation model can evaluate tank bottom corrosion accurately and realize acoustic emission online testing intelligent evaluation of tank bottom.
... teaspoon of salt 1/2 teaspoon of ground black pepper 1/4 teaspoon of paprika 1 cup of frozen peas 2 small carrots, rinsed, peeled, and diced 1 cup of uncooked rice 1 and 1/2 cups of water Directions ...
Keep the Beat Recipes | NIH MedlinePlus the Magazine
... Cup celery, rinsed and diced 1 Cup pearl onions, raw or frozen 3 Cup low-sodium chicken ... 5 minutes. Add leeks, potatoes, celery, and pearl onions, and continue to cook until the vegetables become ...
Multi-Agent Information Classification Using Dynamic Acquaintance Lists.
ERIC Educational Resources Information Center
Mukhopadhyay, Snehasis; Peng, Shengquan; Raje, Rajeev; Palakal, Mathew; Mostafa, Javed
2003-01-01
Discussion of automated information services focuses on information classification and collaborative agents, i.e. intelligent computer programs. Highlights include multi-agent systems; distributed artificial intelligence; thesauri; document representation and classification; agent modeling; acquaintances, or remote agents discovered through…
Information theory, animal communication, and the search for extraterrestrial intelligence
NASA Astrophysics Data System (ADS)
Doyle, Laurance R.; McCowan, Brenda; Johnston, Simon; Hanser, Sean F.
2011-02-01
We present ongoing research in the application of information theory to animal communication systems with the goal of developing additional detectors and estimators for possible extraterrestrial intelligent signals. Regardless of the species, for intelligence (i.e., complex knowledge) to be transmitted certain rules of information theory must still be obeyed. We demonstrate some preliminary results of applying information theory to socially complex marine mammal species (bottlenose dolphins and humpback whales) as well as arboreal squirrel monkeys, because they almost exclusively rely on vocal signals for their communications, producing signals which can be readily characterized by signal analysis. Metrics such as Zipf's Law and higher-order information-entropic structure are emerging as indicators of the communicative complexity characteristic of an "intelligent message" content within these animals' signals, perhaps not surprising given these species' social complexity. In addition to human languages, for comparison we also apply these metrics to pulsar signals—perhaps (arguably) the most "organized" of stellar systems—as an example of astrophysical systems that would have to be distinguished from an extraterrestrial intelligence message by such information theoretic filters. We also look at a message transmitted from Earth (Arecibo Observatory) that contains a lot of meaning but little information in the mathematical sense we define it here. We conclude that the study of non-human communication systems on our own planet can make a valuable contribution to the detection of extraterrestrial intelligence by providing quantitative general measures of communicative complexity. Studying the complex communication systems of other intelligent species on our own planet may also be one of the best ways to deprovincialize our thinking about extraterrestrial communication systems in general.
Associations of coffee consumption and caffeine intake with mammographic breast density.
Yaghjyan, Lusine; Colditz, Graham; Rosner, Bernard; Gasparova, Aleksandra; Tamimi, Rulla M
2018-05-01
Previous studies suggest that coffee and caffeine intake may be associated with reduced breast cancer risk. We investigated the association of coffee and caffeine intake with mammographic breast density by woman's menopausal status and, in postmenopausal women, by hormone therapy (HT). This study included 4130 cancer-free women within the Nurses' Health Study and Nurses' Health Study II cohorts. Percent breast density (PD) was measured from digitized film mammograms using a computer-assisted thresholding technique and square root-transformed for the analysis. Average cumulative coffee/caffeine consumption was calculated using data from all food frequency questionnaires preceding the mammogram date. Information regarding breast cancer risk factors was obtained from questionnaires closest to the mammogram date. We used generalized linear regression to quantify associations of regular, decaffeinated, and total coffee, and energy-adjusted caffeine intake with percent density. In multivariable analyses, decaffeinated coffee was positively associated with PD in premenopausal women (2+ cups/day: β = 0.23, p trend = 0.03). In postmenopausal women, decaffeinated and total coffee were inversely associated with PD (decaffeinated 2+ cups/day: β = - 0.24, p trend = 0.04; total 4+ cups/day: β = - 0.16, p trend = 0.02). Interaction of decaffeinated coffee with menopausal status was significant (p-interaction < 0.001). Among current HT users, regular coffee and caffeine were inversely associated with PD (regular coffee 4+ cups/day: β = - 0.29, p trend = 0.01; caffeine 4th vs. 1st quartile: β = - 0.32, p trend = 0.01). Among past users, decaffeinated coffee was inversely associated with PD (2+ cups/day β = - 0.70, p trend = 0.02). Associations of decaffeinated coffee with percent density differ by woman's menopausal status. Associations of regular coffee and caffeine with percent density may differ by HT status.
Integrated intelligent systems in advanced reactor control rooms
DOE Office of Scientific and Technical Information (OSTI.GOV)
Beckmeyer, R.R.
1989-01-01
An intelligent, reactor control room, information system is designed to be an integral part of an advanced control room and will assist the reactor operator's decision making process by continuously monitoring the current plant state and providing recommended operator actions to improve that state. This intelligent system is an integral part of, as well as an extension to, the plant protection and control systems. This paper describes the interaction of several functional components (intelligent information data display, technical specifications monitoring, and dynamic procedures) of the overall system and the artificial intelligence laboratory environment assembled for testing the prototype. 10 refs.,more » 5 figs.« less
Social Intelligence: Next Generation Business Intelligence
DOE Office of Scientific and Technical Information (OSTI.GOV)
Troy Hiltbrand
In order for Business Intelligence to truly move beyond where it is today, a shift in approach must occur. Currently, much of what is accomplished in the realm of Business Intelligence relies on reports and dashboards to summarize and deliver information to end users. As we move into the future, we need to get beyond these reports and dashboards to a point where we break out the individual metrics that are embedded in these reports and interact with these components independently. Breaking these pieces of information out of the confines of reports and dashboards will allow them to be dynamicallymore » assembled for delivery in the way that makes most sense to each consumer. With this change in ideology, Business Intelligence will move from the concept of collections of objects, or reports and dashboards, to individual objects, or information components. The Next Generation Business Intelligence suite will translate concepts popularized in Facebook, Flickr, and Digg into enterprise worthy communication vehicles.« less
... into wedges), 1 medium or ¼ cup (35 grams) Bananas, 1 medium Raisins, ¼ cup (35 grams) Fruit leather (dried fruit puree) without added sugar ... into strips, or baby carrots ), 1 cup (130 grams) Snap peas (the pods are edible), 1.5 ...
6 Easy Steps toward healthier eating | NIH MedlinePlus the Magazine
... Good Smoothie Ingredients: 1 cup low-fat strawberry yogurt 1 cup orange juice with added calcium 1 ... cup frozen raspberries Instructions: Combine the low-fat yogurt and the orange juice in a blender and ...
Fast-response cup anemometer features cosine response
NASA Technical Reports Server (NTRS)
Frenzen, P.
1968-01-01
Six-cup, low-inertia anemometer combines high resolution and fast response with a unique ability to sense only the horizontal component of the winds fluctuating rapidly in three dimensions. Cup assemblies are fabricated of expanded polystyrene plastic.
Federal Register 2010, 2011, 2012, 2013, 2014
2012-09-12
... DEPARTMENT OF DEFENSE Office of the Secretary Federal Advisory Committee; Defense Intelligence.... The meeting necessarily includes discussions of classified information relating to DIA's intelligence... capabilities in support of current intelligence operations. Agenda September 26, 2012: [[Page 56193
Keeping Current: Emotional Intelligence and the School Library Media Specialist.
ERIC Educational Resources Information Center
Barron, Daniel D.
1997-01-01
Discusses emotional intelligence and its importance for school library media specialists, based on a book by Daniel Goleman called "Emotional Intelligence." Highlights include managing emotions and relationships; self-motivation; and how emotional intelligence fits in with Standards for Information Literacy. (LRW)
Lamp with a truncated reflector cup
Li, Ming; Allen, Steven C.; Bazydola, Sarah; Ghiu, Camil-Daniel
2013-10-15
A lamp assembly, and method for making same. The lamp assembly includes first and second truncated reflector cups. The lamp assembly also includes at least one base plate disposed between the first and second truncated reflector cups, and a light engine disposed on a top surface of the at least one base plate. The light engine is configured to emit light to be reflected by one of the first and second truncated reflector cups.
Finger-triggered portable PDMS suction cup for equipment-free microfluidic pumping
NASA Astrophysics Data System (ADS)
Lee, Sanghyun; Kim, Hojin; Lee, Wonhyung; Kim, Joonwon
2018-12-01
This study presents a finger-triggered portable polydimethylsiloxane suction cup that enables equipment-free microfluidic pumping. The key feature of this method is that its operation only involves a "pressing-and-releasing" action for the cup placed at the outlet of a microfluidic device, which transports the fluid at the inlet toward the outlet through a microchannel. This method is simple, but effective and powerful. The cup is portable and can easily be fabricated from a three-dimensional printed mold, used without any pre-treatment, reversibly bonded to microfluidic devices without leakage, and applied to various material-based microfluidic devices. The effect of the suction cup geometry and fabrication conditions on the pumping performance was investigated. Furthermore, we demonstrated the practical applications of the suction cup by conducting an equipment-free pumping of thermoplastic-based microfluidic devices and water-in-oil droplet generation.
Ronning, Jeffrey J.
2002-01-01
A mounting apparatus for an electromagnetic device such as a transformer of inductor includes a generally planar metallic plate as a first heat sink, and a metallic mounting cup as a second heat sink. The mounting cup includes a cavity configured to receive the electromagnetic device, the cavity being defined by a base, and an axially-extending annular sidewall extending from the base to a flange portion of the mounting cup. The mounting cup includes first and second passages for allowing the leads of first and second windings of the electromagnetic device to be routed out of the cavity. The cavity is filled with a polyurethane potting resin, and the mounting cup, including the potted electromagnetic device, is mounted to the plate heat sink using fasteners. The mounting cup, which surrounds the electromagnetic device, in combination with the potting resin provides improved thermal transfer to the plate heat sink, as well as providing resistance to vibration and shocks.
ERIC Educational Resources Information Center
Black, Alistair; Brunt, Rodney
1999-01-01
This historical study explores a definition of information management that centers on the ordering and channeling of non-publicly available information within organizations. Highlights three types of organizations: the business corporation; the library; and the state agency, specifically British military intelligence. (Contains 44…
An Expertise Based Energy Information System.
ERIC Educational Resources Information Center
Rosenberg, S.
This paper describes an intelligent decision support system for information on petroleum resources and use currently being designed by the Information Methodology Research Project as the first step in the development of a comprehensive intelligent information system for dealing with energy resources in the United States. The system draws on…
Handling Vagueness as an Intelligent Component of a Materials Information System.
ERIC Educational Resources Information Center
Schudnagis, Monika; Womser-Hacker, Christa
1996-01-01
Discusses vagueness as a problem of materials information system development in the context of information retrieval within the paradigm of information science. Presents a prototype which combines an object-oriented graphical user interface with natural language feedback and correction functionality, as well as intelligent components for graphical…
2013-09-01
Office of the Inspector General OSINT Open Source Intelligence PPD Presidential Policy Directive SIGINT Signals Intelligence SLFC State/Local Fusion...Geospatial Intelligence (GEOINT) from Geographic Information Systems (GIS), and Open Source Intelligence ( OSINT ) from Social Media. GIS is widely...and monitor make it a feasible tool to capitalize on for OSINT . A formalized EM intelligence process would help expedite the processing of such
A critical comparison of ten disposable cup LCAs
DOE Office of Scientific and Technical Information (OSTI.GOV)
Harst, Eugenie van der, E-mail: eugenie.vanderharst@wur.nl; Potting, José, E-mail: jose.potting@wur.nl; Environmental Strategies Research
Disposable cups can be made from conventional petro-plastics, bioplastics, or paperboard (coated with petro-plastics or bioplastics). This study compared ten life cycle assessment (LCA) studies of disposable cups with the aim to evaluate the robustness of their results. The selected studies have only one impact category in common, namely climate change with global warming potential (GWP) as its category indicator. Quantitative GWP results of the studies were closer examined. GWPs within and across each study show none of the cup materials to be consistently better than the others. Comparison of the absolute GWPs (after correction for the cup volume) alsomore » shows no consistent better or worse cup material. An evaluation of the methodological choices and the data sets used in the studies revealed their influence on the GWP. The differences in GWP can be attributed to a multitude of factors, i.e., cup material and weight, production processes, waste processes, allocation options, and data used. These factors basically represent different types of uncertainty. Sensitivity and scenario analyses provided only the influence of one factor at once. A systematic and simultaneous use of sensitivity and scenario analyses could, in a next research, result in more robust outcomes. -- Highlights: • Conflicting results from life cycle assessment (LCA) on disposable cups • GWP results of LCAs did not point to a best or worst cup material. • Differences in GWP results are due to methodological choices and data sets used. • Standardized LCA: transparency of LCA studies, but still different in approaches.« less
Second-order motor planning in children: insights from a cup-manipulation-task.
Wunsch, Kathrin; Weiss, Daniel J; Schack, Thomas; Weigelt, Matthias
2015-07-01
The present study examined the development of anticipatory motor planning in an object manipulation task that has been used to successfully demonstrate motor planning in non-human primates (Weiss et al. in Psychol Sci 18:1063-1068, 2007). Seventy-five participants from four different age groups participated in a cup-manipulation task. One group was preschool children (average age of 5.1 years), two groups were primary school children (7.7 and 9.8 years old respectively) and the final group was comprised of adults. The experimental task entailed reaching for a plastic cup that was vertically suspended in an apparatus in either upright or inverted orientation, removing the cup by its stem and then retrieving a small toy from the inside of the cup. When the cup was inverted in the apparatus, evidence for anticipatory motor planning could be achieved by initially gripping the stem using an inverted (thumb-down) grip posture. We found that when the cup was in upright orientation, all participants reached for the cup using an upright grip (i.e., thumb-up posture). However, when the cup was inverted in the apparatus, only adults consistently used an inverted grasping posture, though the percentage of inverted grips among participants did increase with age. These results suggest a protracted development for anticipatory motor planning abilities in children. Surprisingly, the performance of adults on this task more closely resembles the performance of several nonhuman primate species as opposed to children even at approximately 10 years of age. We discuss how morphological constraints on flexibility may help account for these findings.
Benefit of cup medialization in total hip arthroplasty is associated with femoral anatomy.
Terrier, Alexandre; Levrero Florencio, Francesc; Rüdiger, Hannes A
2014-10-01
Medialization of the cup with a respective increase in femoral offset has been proposed in THA to increase abductor moment arms. Insofar as there are potential disadvantages to cup medialization, it is important to ascertain whether the purported biomechanical benefits of cup medialization are large enough to warrant the downsides; to date, studies regarding this question have disagreed. The purpose of this study was to quantify the effect of cup medialization with a compensatory increase in femoral offset compared with anatomic reconstruction for patients undergoing THA. We tested the hypothesis that there is a (linear) correlation between preoperative anatomic parameters and muscle moment arm increase caused by cup medialization. Fifteen patients undergoing THA were selected, covering a typical range of preoperative femoral offsets. For each patient, a finite element model was built based on a preoperative CT scan. The model included the pelvis, femur, gluteus minimus, medius, and maximus. Two reconstructions were compared: (1) anatomic position of the acetabular center of rotation, and (2) cup medialization compensated by an increase in the femoral offset. Passive abduction-adduction and flexion-extension were simulated in the range of normal gait. Muscle moment arms were evaluated and correlated to preoperative femoral offset, acetabular offset, height of the greater trochanter (relative to femoral center of rotation), and femoral antetorsion angle. The increase of muscle moment arms caused by cup medialization varied among patients. Muscle moment arms increase by 10% to 85% of the amount of cup medialization for abduction-adduction and from -35% (decrease) to 50% for flexion-extension. The change in moment arm was inversely correlated (R(2) = 0.588, p = 0.001) to femoral antetorsion (anteversion), such that patients with less femoral antetorsion gained more in terms of hip muscle moments. No linear correlation was observed between changes in moment arm and other preoperative parameters in this series. The benefit of cup medialization is variable and depends on the individual anatomy. Cup medialization with compensatory increase of the femoral offset may be particularly effective in patients with less femoral antetorsion. However, cup medialization must be balanced against its tradeoffs, including the additional loss of medial acetabular bone stock, and eventual proprioceptive implications of the nonanatomic center of rotation and perhaps joint reaction forces. Clinical studies should better determine the relevance of small changes of moment arms on function and joint reaction forces.
A Cyber Situational Awareness Model for Network Administrators
2017-03-01
environments, the Internet of Things, artificial intelligence , and so on. As users’ data requirements grow more complex, they demand information...security of systems of interest. Further, artificial intelligence is a powerful concept in information technology. Therefore, new research should...look into how to use artificial intelligence to develop CSA. Human interaction with cyber systems is not making networks and their components safer
Assessing Mission Impact of Cyberattacks: Report of the NATO IST-128 Workshop
2015-12-01
simulation) perspective. This would be natural, considering that the cybersecurity problem is highly adversarial in nature. Because it involves intelligent ...be formulated as a partial information game; artificial intelligence techniques might help here. Yet another style of problem formulation that...computational information processing for weapons, intelligence , communication, and logistics systems continues to increase the vulnerability of
An Intelligent Information System for forest management: NED/FVS integration
J. Wang; W.D. Potter; D. Nute; F. Maier; H. Michael Rauscher; M.J. Twery; S. Thomasma; P. Knopp
2002-01-01
An Intelligent Information System (IIS) is viewed as composed of a unified knowledge base, database, and model base. This allows an IIS to provide responses to user queries regardless of whether the query process involves a data retrieval, an inference, a computational method, a problem solving module, or some combination of these. NED-2 is a full-featured intelligent...
Closing Intelligence Gaps: Synchronizing the Collection Management Process
information flow. The US military divides the world into six distinct geographic areas with corresponding commanders managing risk and weighing...analyzed information , creating a mismatch between supply and demand. The result is a burden on all facets of the intelligence process. However, if the target...system, or problem requiring analysis is not collected, intelligence fails. Executing collection management under the traditional tasking process
ERIC Educational Resources Information Center
Aparicio, Fernando; De Buenaga, Manuel; Rubio, Margarita; Hernando, Asuncion
2012-01-01
In recent years there has been a shift in educational methodologies toward a student-centered approach, one which increasingly emphasizes the integration of computer tools and intelligent systems adopting different roles. In this paper we describe in detail the development of an Intelligent Information Access system used as the basis for producing…
Metagram Software - A New Perspective on the Art of Computation.
1981-10-01
numober) Computer Programming Information and Analysis Metagramming Philosophy Intelligence Information Systefs Abstraction & Metasystems Metagranmming...control would also serve well in the analysis of military and political intelligence, and in other areas where highly abstract methods of thought serve...needed in intelligence because several levels of abstraction are involved in a political or military system, because analysis entails a complex interplay
ERIC Educational Resources Information Center
Daniels, Daniel B., III
2014-01-01
There is a lack of literature linking end-user behavior to the availability of open-source intelligence (OSINT). Most OSINT literature has been focused on the use and assessment of open-source intelligence, not the proliferation of personally or organizationally identifiable information (PII/OII). Additionally, information security studies have…
Interdisciplinary Study on Artificial Intelligence.
1983-07-01
systems, uiophysics of information processing, cognitive science, and traditional artificial intelligence. The objective behi d this objective was to...information processing, cognitive science, and traditional * artificial intelligence. The objective behind this objective was to provide a vehicle for reviewing...Another departure from ’classical’ neurodynamics must be sought in the strong coupling between the micro and macroscopic scales. No other physical mechanism
Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-03
... DEPARTMENT OF DEFENSE Office of the Secretary Federal Advisory Committee; Defense Intelligence.... The meeting necessarily includes discussions of classified information relating to DIA's intelligence... support of current intelligence operations. Agenda January 22, 2013: Ms. Ellen M. Ardrey, Designated Call...
Effects of intelligibility on working memory demand for speech perception.
Francis, Alexander L; Nusbaum, Howard C
2009-08-01
Understanding low-intelligibility speech is effortful. In three experiments, we examined the effects of intelligibility on working memory (WM) demands imposed by perception of synthetic speech. In all three experiments, a primary speeded word recognition task was paired with a secondary WM-load task designed to vary the availability of WM capacity during speech perception. Speech intelligibility was varied either by training listeners to use available acoustic cues in a more diagnostic manner (as in Experiment 1) or by providing listeners with more informative acoustic cues (i.e., better speech quality, as in Experiments 2 and 3). In the first experiment, training significantly improved intelligibility and recognition speed; increasing WM load significantly slowed recognition. A significant interaction between training and load indicated that the benefit of training on recognition speed was observed only under low memory load. In subsequent experiments, listeners received no training; intelligibility was manipulated by changing synthesizers. Improving intelligibility without training improved recognition accuracy, and increasing memory load still decreased it, but more intelligible speech did not produce more efficient use of available WM capacity. This suggests that perceptual learning modifies the way available capacity is used, perhaps by increasing the use of more phonetically informative features and/or by decreasing use of less informative ones.
32 CFR 319.6 - Disclosure of requested information to individuals.
Code of Federal Regulations, 2010 CFR
2010-07-01
... DEFENSE (CONTINUED) PRIVACY PROGRAM DEFENSE INTELLIGENCE AGENCY PRIVACY PROGRAM § 319.6 Disclosure of requested information to individuals. The Defense Intelligence Agency, upon receiving a request for...
32 CFR 319.6 - Disclosure of requested information to individuals.
Code of Federal Regulations, 2014 CFR
2014-07-01
... DEFENSE (CONTINUED) PRIVACY PROGRAM DEFENSE INTELLIGENCE AGENCY PRIVACY PROGRAM § 319.6 Disclosure of requested information to individuals. The Defense Intelligence Agency, upon receiving a request for...
32 CFR 319.6 - Disclosure of requested information to individuals.
Code of Federal Regulations, 2012 CFR
2012-07-01
... DEFENSE (CONTINUED) PRIVACY PROGRAM DEFENSE INTELLIGENCE AGENCY PRIVACY PROGRAM § 319.6 Disclosure of requested information to individuals. The Defense Intelligence Agency, upon receiving a request for...
The association between intelligence and lifespan is mostly genetic.
Arden, Rosalind; Luciano, Michelle; Deary, Ian J; Reynolds, Chandra A; Pedersen, Nancy L; Plassman, Brenda L; McGue, Matt; Christensen, Kaare; Visscher, Peter M
2016-02-01
Several studies in the new field of cognitive epidemiology have shown that higher intelligence predicts longer lifespan. This positive correlation might arise from socioeconomic status influencing both intelligence and health; intelligence leading to better health behaviours; and/or some shared genetic factors influencing both intelligence and health. Distinguishing among these hypotheses is crucial for medicine and public health, but can only be accomplished by studying a genetically informative sample. We analysed data from three genetically informative samples containing information on intelligence and mortality: Sample 1, 377 pairs of male veterans from the NAS-NRC US World War II Twin Registry; Sample 2, 246 pairs of twins from the Swedish Twin Registry; and Sample 3, 784 pairs of twins from the Danish Twin Registry. The age at which intelligence was measured differed between the samples. We used three methods of genetic analysis to examine the relationship between intelligence and lifespan: we calculated the proportion of the more intelligent twins who outlived their co-twin; we regressed within-twin-pair lifespan differences on within-twin-pair intelligence differences; and we used the resulting regression coefficients to model the additive genetic covariance. We conducted a meta-analysis of the regression coefficients across the three samples. The combined (and all three individual samples) showed a small positive phenotypic correlation between intelligence and lifespan. In the combined sample observed r = .12 (95% confidence interval .06 to .18). The additive genetic covariance model supported a genetic relationship between intelligence and lifespan. In the combined sample the genetic contribution to the covariance was 95%; in the US study, 84%; in the Swedish study, 86%, and in the Danish study, 85%. The finding of common genetic effects between lifespan and intelligence has important implications for public health, and for those interested in the genetics of intelligence, lifespan or inequalities in health outcomes including lifespan. © The Author 2015; Published by Oxford University Press on behalf of the International Epidemiological Association.
The association between intelligence and lifespan is mostly genetic
Arden, Rosalind; Deary, Ian J; Reynolds, Chandra A; Pedersen, Nancy L; Plassman, Brenda L; McGue, Matt; Christensen, Kaare; Visscher, Peter M
2016-01-01
Abstract Background: Several studies in the new field of cognitive epidemiology have shown that higher intelligence predicts longer lifespan. This positive correlation might arise from socioeconomic status influencing both intelligence and health; intelligence leading to better health behaviours; and/or some shared genetic factors influencing both intelligence and health. Distinguishing among these hypotheses is crucial for medicine and public health, but can only be accomplished by studying a genetically informative sample. Methods: We analysed data from three genetically informative samples containing information on intelligence and mortality: Sample 1, 377 pairs of male veterans from the NAS-NRC US World War II Twin Registry; Sample 2, 246 pairs of twins from the Swedish Twin Registry; and Sample 3, 784 pairs of twins from the Danish Twin Registry. The age at which intelligence was measured differed between the samples. We used three methods of genetic analysis to examine the relationship between intelligence and lifespan: we calculated the proportion of the more intelligent twins who outlived their co-twin; we regressed within-twin-pair lifespan differences on within-twin-pair intelligence differences; and we used the resulting regression coefficients to model the additive genetic covariance. We conducted a meta-analysis of the regression coefficients across the three samples. Results: The combined (and all three individual samples) showed a small positive phenotypic correlation between intelligence and lifespan. In the combined sample observed r = .12 (95% confidence interval .06 to .18). The additive genetic covariance model supported a genetic relationship between intelligence and lifespan. In the combined sample the genetic contribution to the covariance was 95%; in the US study, 84%; in the Swedish study, 86%, and in the Danish study, 85%. Conclusions: The finding of common genetic effects between lifespan and intelligence has important implications for public health, and for those interested in the genetics of intelligence, lifespan or inequalities in health outcomes including lifespan. PMID:26213105
Trust metrics in information fusion
NASA Astrophysics Data System (ADS)
Blasch, Erik
2014-05-01
Trust is an important concept for machine intelligence and is not consistent across many applications. In this paper, we seek to understand trust from a variety of factors: humans, sensors, communications, intelligence processing algorithms and human-machine displays of information. In modeling the various aspects of trust, we provide an example from machine intelligence that supports the various attributes of measuring trust such as sensor accuracy, communication timeliness, machine processing confidence, and display throughput to convey the various attributes that support user acceptance of machine intelligence results. The example used is fusing video and text whereby an analyst needs trust information in the identified imagery track. We use the proportional conflict redistribution rule as an information fusion technique that handles conflicting data from trusted and mistrusted sources. The discussion of the many forms of trust explored in the paper seeks to provide a systems-level design perspective for information fusion trust quantification.
From intelligence to evidence-based healthcare: a purchasing odyssey.
Booth, A; Hey, S
1995-12-01
Since the appearance of the NHS Executive's guidance document, Purchasing Intelligence (1991), efforts have been concentrated on the development of 'purchasing intelligence facilities' staffed, in the main, by health librarians. However, the concept of 'intelligence' has a wider dimension that impacts upon the whole culture of an organization. The authors examine purchasing organizations against popular theories of organizational development. The characteristics of Handy's Task culture, with Athena as its patron, may be observed in many authorities. Using the results of two surveys, conducted in March 1995, they identify some key information management issues involving structure, tasks, technology and people. Skills in information 'transformation' must be acquired by all staff in purchasing authorities. The intelligence officer must become a modern-day Odysseus if the intelligence facility is to 'survive and thrive'.
Song, Xinggui; Ni, Ming; Li, Heng; Li, Xin; Li, Xiang; Fu, Jun; Chen, Jiying
2018-05-23
The impact of surgeon handedness on acetabular cup orientation in total hip arthroplasty (THA) is not well studied. The aim of our study is to investigate the difference of cup orientation in bilateral THA performed by right-handed surgeons using posterolateral approach and which cup could be fitter to Lewinneck's safe zone. The study consisted of 498 patients that underwent bilateral THA by three right-handed surgeons in our hospital. Postoperative acetabular cup anteversion and abduction on an anteroposterior pelvic radiograph were measured by Orthoview software (Orthoview LLC, Jacksonville, Florida). Furthermore, the percentage of cup placement within the safe zone was compared. The mean anteversion was 25.28 (25.28° ± 7.16°) in left THA and 22.01 (22.01° ± 6.35°) in right THA (p < 0.001). The mean abduction was 37.50 (37.50° ± 6.76°) in left THA and 38.59 (38.59° ± 6.84°) in right THA (p = 0.011). In the left side, the cup was positioned in Lewinnek's safe zone in 52% for anteversion, 87% for abduction, and 46% for both anteversion and abduction. But the cup placement within Lewinnek's safe zone was 71, 88, and 62% in the right side, respectively. There were significant differences in the percentage of acetabular cup placement within the safe zone for anteversion (p < 0.001) and for both anteversion and inclination (p < 0.001). Dislocation occurred in 7.0% (35/498) of cases in left THA and 3.2% (16/498) in right THA. The percentages of patients experiencing dislocation were significantly different between the two sides (p = 0.006). This current study demonstrated that surgeon handedness is likely to be a contributing factor that affects cup inclination and anteversion in bilateral THA and that the placement of cup performed by dominant hands of surgeons is more accurate than that performed by non-dominant sides.
Building an Information Resource Center for Competitive Intelligence.
ERIC Educational Resources Information Center
Martin, J. Sperling
1992-01-01
Outlines considerations in the design of a Competitive Intelligence Information Resource Center (CIIRC), which is needed by business organizations for effective strategic decision making. Discussed are user needs, user participation, information sources, technology and interface design, operational characteristics, and planning for implementation.…
A Multi-Agent System for Intelligent Online Education.
ERIC Educational Resources Information Center
O'Riordan, Colm; Griffith, Josephine
1999-01-01
Describes the system architecture of an intelligent Web-based education system that includes user modeling agents, information filtering agents for automatic information gathering, and the multi-agent interaction. Discusses information management; user interaction; support for collaborative peer-peer learning; implementation; testing; and future…
32 CFR 2800.4 - General information.
Code of Federal Regulations, 2012 CFR
2012-07-01
... Compartmented Intelligence Information will be controlled by the Assistant to the Vice President for National... procedures and insure accountability. (i) Loss or compromise. Any person who has knowledge of loss of... required for release of Sensitive Compartmented Intelligence Information. The names of personnel cleared...
32 CFR 2800.4 - General information.
Code of Federal Regulations, 2014 CFR
2014-07-01
... Compartmented Intelligence Information will be controlled by the Assistant to the Vice President for National... procedures and insure accountability. (i) Loss or compromise. Any person who has knowledge of loss of... required for release of Sensitive Compartmented Intelligence Information. The names of personnel cleared...
32 CFR 2800.4 - General information.
Code of Federal Regulations, 2013 CFR
2013-07-01
... Compartmented Intelligence Information will be controlled by the Assistant to the Vice President for National... procedures and insure accountability. (i) Loss or compromise. Any person who has knowledge of loss of... required for release of Sensitive Compartmented Intelligence Information. The names of personnel cleared...
Computational intelligence and neuromorphic computing potential for cybersecurity applications
NASA Astrophysics Data System (ADS)
Pino, Robinson E.; Shevenell, Michael J.; Cam, Hasan; Mouallem, Pierre; Shumaker, Justin L.; Edwards, Arthur H.
2013-05-01
In today's highly mobile, networked, and interconnected internet world, the flow and volume of information is overwhelming and continuously increasing. Therefore, it is believed that the next frontier in technological evolution and development will rely in our ability to develop intelligent systems that can help us process, analyze, and make-sense of information autonomously just as a well-trained and educated human expert. In computational intelligence, neuromorphic computing promises to allow for the development of computing systems able to imitate natural neurobiological processes and form the foundation for intelligent system architectures.
An Analysis of Student Model Portability
ERIC Educational Resources Information Center
Valdés Aguirre, Benjamín; Ramírez Uresti, Jorge A.; du Boulay, Benedict
2016-01-01
Sharing user information between systems is an area of interest for every field involving personalization. Recommender Systems are more advanced in this aspect than Intelligent Tutoring Systems (ITSs) and Intelligent Learning Environments (ILEs). A reason for this is that the user models of Intelligent Tutoring Systems and Intelligent Learning…
Federal Register 2010, 2011, 2012, 2013, 2014
2012-06-26
... DEPARTMENT OF DEFENSE Office of the Secretary Federal Advisory Committee; Defense Intelligence... meeting necessarily includes discussions of classified information relating to DIA's intelligence... capabilities in support of current intelligence operations. Agenda July 23, 2012 1 p.m.--Call to Order Mr...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-03-28
... DEPARTMENT OF DEFENSE Office of the Secretary Federal Advisory Committee; Defense Intelligence... meeting necessarily includes discussions of classified information relating to DIA's intelligence... capabilities in support of current intelligence operations. Agenda May 2, 2012 S 8:30 a.m Convene Advisory...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-14
... DEPARTMENT OF DEFENSE Office of the Secretary Federal Advisory Committee; Defense Intelligence.... The meetings necessarily include discussions of classified information relating to DIA's intelligence... current intelligence operations. Agenda December 2, 2011 8:30 a.m Convene Advisory Mr. William Caniano...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-01-17
... DEPARTMENT OF DEFENSE Office of the Secretary Federal Advisory Committee; Defense Intelligence.... The meetings necessarily include discussions of classified information relating to DIA's intelligence... intelligence operations. Agenda February 24, 2012 8:30 a.m Convene Advisory Mr. William Caniano, Board Meeting...
ERIC Educational Resources Information Center
Information Technology Quarterly, 1985
1985-01-01
This issue of "Information Technology Quarterly" is devoted to the theme of "Artificial Intelligence." It contains two major articles: (1) Artificial Intelligence and Law" (D. Peter O'Neill and George D. Wood); (2) "Artificial Intelligence: A Long and Winding Road" (John J. Simon, Jr.). In addition, it contains two sidebars: (1) "Calculating and…
Patel, Anisha I; Grummon, Anna H; Hampton, Karla E; Oliva, Ariana; McCulloch, Charles E; Brindis, Claire D
2016-07-07
US legislation requires that schools offer free drinking water where meals are served. However, little information is available about what types of water delivery systems schools should install to meet such requirements. The study objective was to examine the efficacy and cost of 2 water delivery systems (water dispensers and bottleless water coolers) in increasing students' lunchtime intake of water in low-income middle schools. In 2013, twelve middle schools in the San Francisco Bay Area participated in a cluster randomized controlled trial in which they received 6 weeks of promotional activities, received provision of cups, and were assigned to 1 of 2 cafeteria water delivery systems: water dispensers or bottleless water coolers (or schools served as a control). Student surveys (n = 595) and observations examined the interventions' effect on students' beverage intake and staff surveys and public data assessed intervention cost. Analysis occurred from 2013 through 2015. Mixed-effects logistic regression, accounting for clustering and adjustment for student sociodemographic characteristics, demonstrated a significant increase in the odds of students drinking water in schools with promotion plus water dispensers and cups (adjusted odds ratio = 3.1; 95% confidence interval, 1.4-6.7; P = .004) compared with schools with traditional drinking fountains and no cups or promotion. The cost of dispenser and bottleless water cooler programs was similar ($0.04 per student per day). Instead of relying on traditional drinking fountains, schools should consider installing water sources, such as plastic dispensers with cups, as a low-cost, effective means for increasing students' water intake.
Bippus, Alexander C; Stockey, Ruth A; Rothwell, Gar W; Tomescu, Alexandru M F
2017-04-01
Diverse in modern ecosystems, mosses are dramatically underrepresented in the fossil record. Furthermore, most pre-Cenozoic mosses are known only from compression fossils, lacking detailed anatomical information. When preserved, anatomy vastly improves resolution in the systematic placement of fossils. Lower Cretaceous deposits at Apple Bay (Vancouver Island, British Columbia, Canada) contain a diverse anatomically preserved flora that includes numerous bryophytes, many of which have yet to be characterized. Among them is a polytrichaceous moss that is described here. Fossil moss gametophytes preserved in four carbonate concretions were studied in serial sections prepared using the cellulose acetate peel technique. We describe Meantoinea alophosioides gen. et sp. nov., a polytrichaceous moss with terminal gemma cups containing stalked, lenticular gemmae. Leaves with characteristic costal anatomy, differentiated into sheathing base and free lamina and bearing photosynthetic lamellae, along with a conducting strand in the stem, place Meantoinea in family Polytrichaceae. The bistratose leaf lamina with an adaxial layer of mamillose cells, short photosynthetic lamellae restricted to the costa, and presence of gemma cups indicate affinities with basal members of the Polytrichaceae, such as Lyellia , Bartramiopsis , and Alophosia . Meantoinea alophosioides enriches the documented moss diversity of an already-diverse Early Cretaceous plant fossil assemblage. This is the third moss described from the Apple Bay plant fossil assemblage and represents the first occurrence of gemma cups in a fossil moss. It is also the oldest unequivocal record of Polytrichaceae, providing a hard minimum age for the group of 136 million years. © 2017 Botanical Society of America.
Kakizaki, Masako; Nakaya, Naoki; Tsuboya, Toru; Sone, Toshimasa; Kuriyama, Shinichi; Hozawa, Atsushi; Tsuji, Ichiro
2012-01-01
Background: Previous studies have reported that green tea consumption is associated with a lower risk of diseases that cause functional disability, such as stroke, cognitive impairment, and osteoporosis. Although it is expected that green tea consumption would lower the risk of incident functional disability, this has never been investigated directly. Objective: The objective was to determine the association between green tea consumption and incident functional disability in elderly individuals. Design: We conducted a prospective cohort study in 13,988 Japanese individuals aged ≥65 y. Information on daily green tea consumption and other lifestyle factors was collected via questionnaire in 2006. Data on functional disability were retrieved from the public Long-term Care Insurance database, in which subjects were followed up for 3 y. We used Cox proportional hazards regression analysis to investigate the association between green tea consumption and functional disability. Results: The 3-y incidence of functional disability was 9.4% (1316 cases). The multiple-adjusted HR (95% CI) of incident functional disability was 0.90 (0.77, 1.06) among respondents who consumed 1–2 cups green tea/d, 0.75 (0.64, 0.88) for those who consumed 3–4 cups/d, and 0.67 (0.57, 0.79) for those who consumed ≥5 cups/d in comparison with those who consumed <1 cup/d (P-trend < 0.001). Conclusion: Green tea consumption is significantly associated with a lower risk of incident functional disability, even after adjustment for possible confounding factors. PMID:22277550
The Evolution of Computer-Assisted Total Hip Arthroplasty and Relevant Applications.
Chang, Jun-Dong; Kim, In-Sung; Bhardwaj, Atul M; Badami, Ramachandra N
2017-03-01
In total hip arthroplasty (THA), the accurate positioning of implants is the key to achieve a good clinical outcome. Computer-assisted orthopaedic surgery (CAOS) has been developed for more accurate positioning of implants during the THA. There are passive, semi-active, and active systems in CAOS for THA. Navigation is a passive system that only provides information and guidance to the surgeon. There are 3 types of navigation: imageless navigation, computed tomography (CT)-based navigation, and fluoroscopy-based navigation. In imageless navigation system, a new method of registration without the need to register the anterior pelvic plane was introduced. CT-based navigation can be efficiently used for pelvic plane reference, the functional pelvic plane in supine which adjusts anterior pelvic plane sagittal tilt for targeting the cup orientation. Robot-assisted system can be either active or semi-active. The active robotic system performs the preparation for implant positioning as programmed preoperatively. It has been used for only femoral implant cavity preparation. Recently, program for cup positioning was additionally developed. Alternatively, for ease of surgeon acceptance, semi-active robot systems are developed. It was initially applied only for cup positioning. However, with the development of enhanced femoral workflows, this system can now be used to position both cup and stem. Though there have been substantial advancements in computer-assisted THA, its use can still be controversial at present due to the steep learning curve, intraoperative technical issues, high cost and etc. However, in the future, CAOS will certainly enable the surgeon to operate more accurately and lead to improved outcomes in THA as the technology continues to evolve rapidly.
Differential effects of tamoxifen and anastrozole on optic cup size in breast cancer survivors
Toomey, Maureen D.; Falardeau, Julie; Samples, John R.; Vetto, John T.
2007-01-01
Introduction The main purpose of this study was to determine whether the optic cups of tamoxifen users and anastrozole users differ in size, with the cups of the tamoxifen users being smaller. Methods Optic nerve head (ONH) topography was measured using a commercially available, confocal scanning laser ophthalmoscope for three populations of amenorrheic women ages 40–69 years: subjects using (1) tamoxifen (20 mg/day) or (2) anastrozole (1 mg/day) for ≤ 2 years as adjuvant therapy after successful primary treatment for breast cancer, and (3) control subjects with no breast cancer histories and not using any hormonal medication. All subjects had excellent visual acuity and healthy eyes, based on conventional photographic assessment. Results The cup volumes of the tamoxifen users were shown to be significantly smaller than the cup volumes of the anastrozole users, which were indistinguishable from normal. Because the cup volumes of the tamoxifen users decreased markedly with age at about 50 years and because anastrozole is indicated only for post-menopausal women, comparisons were reassessed for subjects older than 50 years. For these subjects, the cup volumes of the tamoxifen users averaged less than half of the volumes for each of the other two subject groups, and significant between-group differences existed in both the lateral (cup area) and axial (cup depth) directions. In contrast, any between-group differences at the ONH margin were small and not significant. Conclusions The results of this study suggest that the ONH be assessed biomorphometrically for tamoxifen users reporting visual change that cannot be attributed to non-tamoxifen causes. The ability of modern intraocular imaging techniques to reveal anatomic change on the order of tens of microns may be useful for assessing tamoxifen-induced effects occurring simultaneously elsewhere in the brain, particularly since the presence of small cups is consistent with the possibility of tamoxifen-induced astrocytic swelling. PMID:17260092
Howard, Courtney; Rose, Caren Lee; Trouton, Konia; Stamm, Holly; Marentette, Danielle; Kirkpatrick, Nicole; Karalic, Sanja; Fernandez, Renee; Paget, Julie
2011-06-01
To determine whether menstrual cups are a viable alternative to tampons. Randomized controlled trial. Prince George, Victoria, and Vancouver, BC. A total of 110 women aged 19 to 40 years who had previously used tampons as their main method of menstrual management. Participants were randomized into 2 groups, a tampon group and a menstrual cup group. Using online diaries, participants tracked 1 menstrual cycle using their regular method and 3 menstrual cycles using the method of their allocated group. Overall satisfaction; secondary outcomes included discomfort, urovaginal infection, cost, and waste. Forty-seven women in each group completed the final survey, 5 of whom were subsequently excluded from analysis (3 from the tampon group and 2 from the menstrual cup group). Overall satisfaction on a 7-point Likert scale was higher for the menstrual cup group than for the tampon group (mean [standard deviation] score 5.4 [1.5] vs 5.0 [1.0], respectively; P=.04). Approximately 91% of women in the menstrual cup group said they would continue to use the cup and recommend it to others. Women used a median of 13 menstrual products per cycle, or 169 products per year, which corresponds to approximately 771,248,400 products used annually in Canada. Estimated cost for tampon use was $37.44 a year (similar to the retail cost of 1 menstrual cup). Subjective vaginal discomfort was initially higher in the menstrual cup group, but the discomfort decreased with continued use. There was no significant difference in physician-diagnosed urovaginal symptoms between the 2 groups. Both of the menstrual management methods evaluated were well tolerated by subjects. Menstrual cups are a satisfactory alternative to tampons and have the potential to be a sustainable solution to menstrual management, with moderate cost savings and much-reduced environmental effects compared with tampons. Trial registration number C06-0478 (ClinicalTrials.gov).
Coffee and depression in Korea: the fifth Korean National Health and Nutrition Examination Survey.
Park, R J; Moon, J D
2015-04-01
There is substantial interest in the health effects of coffee because it is the leading worldwide beverage after water. Existing literature on the connection between depression and coffee is scarce, and studies have yielded inconsistent results. The aim of this study was to examine the association between coffee consumption and depression in the Korean population. We conducted a cross-sectional study in 10,177 Korean individuals aged 20-97 years who participated in the fifth Korean National Health and Nutrition Examination Survey. Consumption of coffee and depression were assessed using a questionnaire. Multiple logistic regression analysis was used to compute odds ratios (ORs) and 95% confidence intervals (CIs) for depression. The lifetime prevalence of self-reported depression was 14.0% and that of self-reported clinical depression was 3.7%. After adjustment for potential confounders, the adjusted ORs for self-reported depression across coffee consumption categories were 1.00 (reference) for less than one cup/week, 0.84 (95% CI: 0.66, 1.07) for one to six cups/week, 0.63 (95% CI: 0.51, 0.79) for one cup/day, 0.69 (95% CI: 0.54, 0.88) for two cups/day and 0.58 (95% CI: 0.44, 0.76) for three or more cups/day (P for trend, <0.01). A similar association was observed for self-reported clinical depression, for which the multiple-adjusted ORs were 1.00 (reference) for less than one cup/week, 0.61 (95% CI: 0.40, 0.92) for one to six cups/week, 0.51 (95% CI: 0.34, 0.74) for one cup/day, 0.57 (95% CI: 0.39, 0.84) for two cups/day and 0.41 (95% CI: 0.24, 0.70) for three or more cups/day, respectively (P for trend, <0.01). These findings support a possible protective effect of coffee on the risk of depression.
Cupping for chronic nonspecific neck pain: a 2-year follow-up.
Lauche, Romy; Cramer, Holger; Langhorst, Jost; Dobos, Gustav
2013-01-01
Several trials have shown that cupping might be an effective treatment for chronic nonspecific neck pain, but little is known about the long-term effectiveness. This study aimed to investigate long-term effects of a short series of cupping; therefore additional follow-up measurements were conducted 2 years after completion of 3 studies. Participants from 3 randomized waitlist controlled trials on cupping for chronic nonspecific neck pain were followed 2 years after treatment. Outcome measures included neck pain intensity (100 mm Visual Analog Scale; VAS), functional disability (Neck Disability Index, NDI), and health-related quality of life (Short Form 36 Health Survey Questionnaire; SF-36). 133 of 150 patients had received cupping treatment and were contacted; 82 of them (61.7%) returned the follow-up questionnaires. No effect was found for neck pain intensity, but for physical function (∆ NDI: -3.15; 95% CI: -5.89; -0.41; p = 0.025) and quality of life (∆ physical component summary: 2.97; 95% CI: 0.97; 4.97; p = 0.004; ∆ bodily pain: 14.53; 95 % CI: 9.67; 19.39; p < 0.001). Mean duration of cupping effect was 8.9 ± 8.7 months with 16 patients reporting that neck pain had not yet reached the level before cupping. The majority of the patients did not continue cupping therapy, mostly due to lack of providers, costs or loss of interest. A series of cupping treatments did not influence neck pain intensity on the longer term, however significant increases were found for physical function and quality of life in patients with chronic nonspecific neck pain. Due to the considerable drop-out rate conclusions are limited. There is evidence suggesting that cupping treatment might have sustainable effects in some patients. Further randomized controlled trials with long-term follow-up are urgently needed for conclusive judgment of long-term effectiveness. © 2013 S. Karger GmbH, Freiburg.
Ely, Amanda L; El-Dairi, Mays A; Freedman, Sharon F
2014-11-01
To identify optic nerve head (ONH) cupping reversal and associated optical coherence tomography (OCT) and Humphrey visual field changes in pediatric glaucoma. Retrospective observational case series. Sequential surgical cases of juvenile open-angle glaucoma (OAG) or primary congenital glaucoma (PCG) with sustained postoperative intraocular pressure (IOP) reduction. Group 1 had preoperative and postoperative ONH photographs and OCT; Group 2 had preoperative clinical ONH assessment and postoperative imaging. Cupping evaluation was confirmed by masked glaucoma and neuro-ophthalmology specialists. Of 80 cases, 9 eyes (9 children) met criteria for Group 1; 24 eyes (19 children) met criteria for Group 2. Group 1: Five of 9 eyes (56%) demonstrated cupping reversal, with preoperative vs postoperative mean IOP 34.2 ± 6.6 mm Hg vs 10.6 ± 4.1 mm Hg (P < .00001) and mean average retinal nerve fiber layer (RNFL) 71.0 ± 30 μm vs 62.8 ± 24 μm (P = .4), respectively. RNFL was stable in 4 of 5 eyes (all juvenile OAG), but thinned (Δ = -41 μm) in 1 eye with PCG. Humphrey visual fields (reliable in 2 of 3 eyes) showed no significant change. Group 2: Fourteen of 24 PCG eyes (58%) demonstrated cupping reversal, with preoperative vs postoperative mean IOP 36.1 ± 8.9 mm Hg vs 13.3 ± 2.1 mm Hg (P < .00001). Two eyes had thin RNFL postoperatively despite healthy-appearing ONH. Postoperative RNFL showed statistically significant linear correlation with preoperative (but not postoperative) cup-to-disc ratio. Limitations include small numbers, few reliable Humphrey visual fields, and absent preoperative imaging (Group 2). Some eyes with IOP reduction and ONH cupping reversal show continued RNFL thinning postoperatively. The preoperative ONH cup-to-disc ratio predicted the postoperative RNFL better than the postoperative "reversed and smaller" cup-to-disc ratio. Cupping reversal in pediatric glaucoma may not predict improved ONH health and deserves further study. Copyright © 2014 Elsevier Inc. All rights reserved.
Phosphorus-Rich Copper Phosphide Nanowires for Field-Effect Transistors and Lithium-Ion Batteries.
Li, Guo-An; Wang, Chiu-Yen; Chang, Wei-Chung; Tuan, Hsing-Yu
2016-09-27
Phosphorus-rich transition metal phosphide CuP2 nanowires were synthesized with high quality and high yield (∼60%) via the supercritical fluid-liquid-solid (SFLS) growth at 410 °C and 10.2 MPa. The obtained CuP2 nanowires have a high aspect ratio and exhibit a single crystal structure of monoclinic CuP2 without any impurity phase. CuP2 nanowires have progressive improvement for semiconductors and energy storages compared with bulk CuP2. Being utilized for back-gate field effect transistor (FET) measurement, CuP2 nanowires possess a p-type behavior intrinsically with an on/off ratio larger than 10(4) and its single nanowire electrical transport property exhibits a hole mobility of 147 cm(2) V(-1) s(-1), representing the example of a CuP2 transistor. In addition, CuP2 nanowires can serve as an appealing anode material for a lithium-ion battery electrode. The discharge capacity remained at 945 mA h g(-1) after 100 cycles, showing a good capacity retention of 88% based on the first discharge capacity. Even at a high rate of 6 C, the electrode still exhibited an outstanding result with a capacity of ∼600 mA h g(-1). Ex-situ transmission electron microscopy and CV tests demonstrate that the stability of capacity retention and remarkable rate capability of the CuP2 nanowires electrode are attributed to the role of the metal phosphide conversion-type lithium storage mechanism. Finally, CuP2 nanowire anodes and LiFePO4 cathodes were assembled into pouch-type lithium batteries offering a capacity over 60 mA h. The full cell shows high capacity and stable capacity retention and can be used as an energy supply to operate electronic devices such as mobile phones and mini 4WD cars.
Prediction of specialty coffee cup quality based on near infrared spectra of green coffee beans.
Tolessa, Kassaye; Rademaker, Michael; De Baets, Bernard; Boeckx, Pascal
2016-04-01
The growing global demand for specialty coffee increases the need for improved coffee quality assessment methods. Green bean coffee quality analysis is usually carried out by physical (e.g. black beans, immature beans) and cup quality (e.g. acidity, flavour) evaluation. However, these evaluation methods are subjective, costly, time consuming, require sample preparation and may end up in poor grading systems. This calls for the development of a rapid, low-cost, reliable and reproducible analytical method to evaluate coffee quality attributes and eventually chemical compounds of interest (e.g. chlorogenic acid) in coffee beans. The aim of this study was to develop a model able to predict coffee cup quality based on NIR spectra of green coffee beans. NIR spectra of 86 samples of green Arabica beans of varying quality were analysed. Partial least squares (PLS) regression method was used to develop a model correlating spectral data to cupping score data (cup quality). The selected PLS model had a good predictive power for total specialty cup quality and its individual quality attributes (overall cup preference, acidity, body and aftertaste) showing a high correlation coefficient with r-values of 90, 90,78, 72 and 72, respectively, between measured and predicted cupping scores for 20 out of 86 samples. The corresponding root mean square error of prediction (RMSEP) was 1.04, 0.22, 0.27, 0.24 and 0.27 for total specialty cup quality, overall cup preference, acidity, body and aftertaste, respectively. The results obtained suggest that NIR spectra of green coffee beans are a promising tool for fast and accurate prediction of coffee quality and for classifying green coffee beans into different specialty grades. However, the model should be further tested for coffee samples from different regions in Ethiopia and test if one generic or region-specific model should be developed. Copyright © 2015 Elsevier B.V. All rights reserved.
Yamada, Kazuki; Endo, Hirosuke; Tetsunaga, Tomonori; Miyake, Takamasa; Sanki, Tomoaki; Ozaki, Toshifumi
2018-01-01
The accuracy of various navigation systems used for total hip arthroplasty has been described, but no publications reported the accuracy of cup orientation in computed tomography (CT)-based 2D-3D (two-dimensional to three-dimensional) matched navigation. In a prospective, randomized controlled study, 80 hips including 44 with developmental dysplasia of the hips were divided into a CT-based 2D-3D matched navigation group (2D-3D group) and a paired-point matched navigation group (PPM group). The accuracy of cup orientation (absolute difference between the intraoperative record and the postoperative measurement) was compared between groups. Additionally, multiple logistic regression analysis was performed to evaluate patient factors affecting the accuracy of cup orientation in each navigation. The accuracy of cup inclination was 2.5° ± 2.2° in the 2D-3D group and 4.6° ± 3.3° in the PPM group (P = .0016). The accuracy of cup anteversion was 2.3° ± 1.7° in the 2D-3D group and 4.4° ± 3.3° in the PPM group (P = .0009). In the PPM group, the presence of roof osteophytes decreased the accuracy of cup inclination (odds ratio 8.27, P = .0140) and the absolute value of pelvic tilt had a negative influence on the accuracy of cup anteversion (odds ratio 1.27, P = .0222). In the 2D-3D group, patient factors had no effect on the accuracy of cup orientation. The accuracy of cup positioning in CT-based 2D-3D matched navigation was better than in paired-point matched navigation, and was not affected by patient factors. It is a useful system for even severely deformed pelvises such as developmental dysplasia of the hips. Copyright © 2017 Elsevier Inc. All rights reserved.
Vertical cup-to-disc ratio measurement for diagnosis of glaucoma on fundus images
NASA Astrophysics Data System (ADS)
Hatanaka, Yuji; Noudo, Atsushi; Muramatsu, Chisako; Sawada, Akira; Hara, Takeshi; Yamamoto, Tetsuya; Fujita, Hiroshi
2010-03-01
Glaucoma is a leading cause of permanent blindness. Retinal fundus image examination is useful for early detection of glaucoma. In order to evaluate the presence of glaucoma, the ophthalmologists determine the cup and disc areas and they diagnose glaucoma using a vertical cup-to-disc ratio. However, determination of the cup area is very difficult, thus we propose a method to measure the cup-to-disc ratio using a vertical profile on the optic disc. First, the blood vessels were erased from the image and then the edge of optic disc was then detected by use of a canny edge detection filter. Twenty profiles were then obtained around the center of the optic disc in the vertical direction on blue channel of the color image, and the profile was smoothed by averaging these profiles. After that, the edge of the cup area on the vertical profile was determined by thresholding technique. Lastly, the vertical cup-to-disc ratio was calculated. Using seventy nine images, including twenty five glaucoma images, the sensitivity of 80% and a specificity of 85% were achieved with this method. These results indicated that this method can be useful for the analysis of the optic disc in glaucoma examinations.
Splash-cup plants accelerate raindrops to disperse seeds.
Amador, Guillermo J; Yamada, Yasukuni; McCurley, Matthew; Hu, David L
2013-02-01
The conical flowers of splash-cup plants Chrysosplenium and Mazus catch raindrops opportunistically, exploiting the subsequent splash to disperse their seeds. In this combined experimental and theoretical study, we elucidate their mechanism for maximizing dispersal distance. We fabricate conical plant mimics using three-dimensional printing, and use high-speed video to visualize splash profiles and seed travel distance. Drop impacts that strike the cup off-centre achieve the largest dispersal distances of up to 1 m. Such distances are achieved because splash speeds are three to five times faster than incoming drop speeds, and so faster than the traditionally studied splashes occurring upon horizontal surfaces. This anomalous splash speed is because of the superposition of two components of momentum, one associated with a component of the drop's motion parallel to the splash-cup surface, and the other associated with film spreading induced by impact with the splash-cup. Our model incorporating these effects predicts the observed dispersal distance within 6-18% error. According to our experiments, the optimal cone angle for the splash-cup is 40°, a value consistent with the average of five species of splash-cup plants. This optimal angle arises from the competing effects of velocity amplification and projectile launching angle.
Burns induced by cupping therapy in a burn center in northeast china.
Jing-Chun, Zhao; Jia-Ao, Yu; Chun-Jing, Xian; Kai, Shi; Lai-Jin, Lu
2014-07-01
Cupping therapy as a curative skill has been developed and applied throughout history. Despite reports of adverse effects, this therapy is considered to be relatively safe with no systemic reviews documenting negative side effects. The aim of this study was to explore methods that avoid the adverse effects sometimes associated with this therapy. Clinical records of 14 outpatients and inpatients that visited the First Hospital of Jilin University (Changchun, China) for management of burn injuries caused by cupping therapy were retrospectively reviewed. Characteristics, history of injury, and treatment of each patient was collected and analyzed. Burn injury induced by cupping therapy was not uncommon. Most of the injuries were mild to moderate and cured by conservative methods without severe complications. The use of wet cupping was more prevalent among injured patients than dry cupping. Cupping therapy as an ancient alternative treatment is still popular with a large number of devoted practitioners. Although there is the potential for injury during the application of this therapy, this is mostly preventable. Standardized training for health care professionals and increased the awareness among the public about the proper methods to administer this therapy to avoid adverse effects is important.
A Zero-Gravity Cup for Drinking Beverages in Microgravity
NASA Technical Reports Server (NTRS)
Pettit, Donald R.; Weislogel, Mark; Concus, Paul; Finn, Robert
2011-01-01
To date, the method for astronauts to drink liquids in microgravity or weightless environments is to suck the liquid from a bag or pouch through a straw. A new beverage cup works in microgravity and allows astronauts to drink liquids from a cup in a manner consistent with that on Earth. The cup is capable of holding beverages with an angled channel running along the wall from the bottom to the lip. In microgravity, a beverage is placed into the cup using the galley dispenser. The angled channel acts as an open passage that contains only two sides where capillary forces move the liquid along the channel until it reaches the top lip where the forces reach an equilibrium and the flow stops. When one sips the liquid at the lip of the channel, the capillary force equilibrium is upset and more liquid flows to the lip from the reservoir at the bottom to re-establish the equilibrium. This sipping process can continue until the total liquid contents of the cup is consumed, leaving only a few residual drops about the same quantity as in a ceramic cup when it is drunk dry on Earth.
Salemyr, Mats; Muren, Olle; Eisler, Thomas; Bodén, Henrik; Chammout, Ghazi; Stark, André; Sköldenberg, Olof
2015-05-01
The purpose of this study was to determine if a new titanium cup with increased porosity resulted in different periacetabular bone loss and migration compared to a porous coated cup. Fifty-one patients with primary hip osteoarthritis were randomized to either a cup with porous titanium construct backside (porous titanium group, n = 25) or a conventional porous coated titanium cup (control group, n = 26). The primary outcome variable was change in periacetabular bone mineral density two years after surgery measured with dual energy X-ray absorptiometry (DXA). Secondary outcomes were implant fixation measured with radiostereometry (RSA) and clinical outcome scores. The pattern of bone remodelling was similar in the two groups with almost complete restoration to baseline values. BMD diminished in the two proximal zones and increased in the two distal zones. After minimal migration up to six months all implants in both groups became stable. We found no difference between the two groups in clinical outcome scores. In this prospective, randomized, controlled trial on a new porous titanium cup we found, compared to the control group, no clinically relevant differences regarding periacetabular bone preservation, implant fixation or clinical outcome up to two years postoperatively.
Code of Federal Regulations, 2014 CFR
2014-07-01
... PROGRAM DEFENSE INTELLIGENCE AGENCY (DIA) FREEDOM OF INFORMATION ACT § 292.1 Purpose. This document implements the “Freedom of Information Act (FOIA),” 5 U.S.C., as amended, with the Defense Intelligence...
Code of Federal Regulations, 2012 CFR
2012-07-01
... PROGRAM DEFENSE INTELLIGENCE AGENCY (DIA) FREEDOM OF INFORMATION ACT § 292.1 Purpose. This document implements the “Freedom of Information Act (FOIA),” 5 U.S.C., as amended, with the Defense Intelligence...
Code of Federal Regulations, 2010 CFR
2010-07-01
... PROGRAM DEFENSE INTELLIGENCE AGENCY (DIA) FREEDOM OF INFORMATION ACT § 292.1 Purpose. This document implements the “Freedom of Information Act (FOIA),” 5 U.S.C., as amended, with the Defense Intelligence...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-23
... CENTRAL INTELLIGENCE AGENCY 32 CFR Part 1901 Privacy Act AGENCY: Central Intelligence Agency. ACTION: Proposed rule. SUMMARY: Consistent with the Privacy Act (PA), the Central Intelligence Agency... the Director, Information Management [[Page 59074
2013-12-01
pollenate information. The effect of this data should be a comprehension that is both geospatial and temporal in nature and can “depict the evolution...information or intelligence that drive them, and typically don’t cross- pollenate , nor are they given incentive to do so without the expressed desire
Federal Register 2010, 2011, 2012, 2013, 2014
2013-07-15
... information, please contact Clark R. Fleming, Field Division Counsel, El Paso Intelligence Center, 11339 SSG... of information, including the validity of the methodology and assumptions used; [[Page 42109... 143. Component: El Paso Intelligence Center, Drug Enforcement Administration, U.S. Department of...
The Scharff-technique: eliciting intelligence from human sources.
Oleszkiewicz, Simon; Granhag, Pär Anders; Montecinos, Sebastian Cancino
2014-10-01
This study is on how to elicit intelligence from human sources. We compared the efficacy of two human intelligence gathering techniques: the Scharff-technique (conceptualized as four different tactics) and the Direct Approach (a combination of open and direct questions). Participants (N = 60) were asked to take on the role of "sources" and were given information about a planned terrorist attack. They were to reveal part of this information in an upcoming interview. Critically, the participants were instructed to strike a balance between not revealing too much or too little information. As predicted, the participants revealed significantly more, and more precise, new information when interviewed with the Scharff-technique (vs. the Direct Approach). Furthermore, and as predicted, the participants in the Scharff condition underestimated how much new information they revealed whereas the participants in the Direct Approach overestimated how much new information they revealed. The study provides rather strong support for the Scharff-technique as an effective human intelligence gathering technique. PsycINFO Database Record (c) 2014 APA, all rights reserved.
Cheaper Custom Shielding Cups For Arc Welding
NASA Technical Reports Server (NTRS)
Morgan, Gene E.
1992-01-01
New way of making special-purpose shielding cups for gas/tungsten arc welding from hobby ceramic greatly reduces cost. Pattern machined in plastic. Plaster-of-paris mold made, and liquid ceramic poured into mold. Cost 90 percent less than cup machined from lava rock.
World cup soccer players tend to be born with sun and moon in adjacent zodiacal signs
Verhulst, J
2000-01-01
The ecliptic elongation of the moon with respect to the sun does not show uniform distribution on the birth dates of the 704 soccer players selected for the 1998 World Cup. However, a uniform distribution is expected on astronomical grounds. The World Cup players show a very pronounced tendency (p = 0.00001) to be born on days when the sun and moon are in adjacent zodiacal signs. Key Words: soccer; World Cup; astrology; moon PMID:11131239
[Analysis on the adverse events of cupping therapy in the application].
Zhou, Xin; Ruan, Jing-wen; Xing, Bing-feng
2014-10-01
The deep analysis has been done on the cases of adverse events and common injury of cupping therapy encountered in recent years in terms of manipulation and patient's constitution. The adverse events of cupping therapy are commonly caused by improper manipulation of medical practitioners, ignoring contraindication and patient's constitution. Clinical practitioners should use cupping therapy cautiously, follow strictly the rules of standard manipulation and medical core system, pay attention to the contraindication and take strict precautions against the occurrence of adverse events.
ERIC Educational Resources Information Center
Kissel, Stanley; Kissel, Pearl
The major purpose of this work is to provide information for teachers about intelligence testing; more specifically, how the revised Wechsler Intelligence Scale for Children (WISC-R) can be used practically. The purpose is not to make teachers into testers, but rather to make them more sophisticiated users of the information that they obtain from…
Federal Register 2010, 2011, 2012, 2013, 2014
2013-04-03
..., Domestic Strategic Intelligence Unit, Office of Intelligence, Warning, Plans and Programs, Drug Enforcement... proposed collection of information, including the validity of the methodology and assumptions used; Enhance...
Knight, O'Rese J; Girkin, Christopher A; Budenz, Donald L; Durbin, Mary K; Feuer, William J
2012-03-01
To determine the effect of race, demographic, and ocular variables on optic nerve head and retinal nerve fiber layer (RNFL) thickness measurements using spectral-domain optical coherence tomography. In a cross-sectional observational study, 284 normal subjects aged 18 to 84 years were evaluated at 7 sites using Cirrus HD-OCT. Disc area, rim area, average cup-disc ratio, vertical cup-disc ratio, cup volume, and average, temporal, superior, nasal, and inferior RNFL thicknesses were calculated. The main outcome measures were associations between Cirrus HD-OCT optic nerve head and RNFL measurements and age, sex, and race. The 284 subjects self-identified as being of European (122), Chinese (63), African (51), or Hispanic (35) descent. After adjusting for the effect of age, there was a statistically significant difference among racial groups for all optic nerve head and RNFL parameters (all P ≤ .005) except rim area (P = .22). Rim area, average cup-disc ratio, vertical cup-disc ratio, and cup volume were moderately associated with disc area (r(2) = 0.15, 0.33, 0.33, and 0.37, respectively). After a linear adjustment for disc area, there was no statistically significant difference among racial groups for any optic nerve head parameter. Individuals of European descent had thinner RNFL measurements except in the temporal quadrant. There are racial differences in optic disc area, average cup-disc ratio, vertical cup-disc ratio, cup volume, and RNFL thickness as measured by Cirrus HD-OCT. These differences should be considered when using Cirrus HD-OCT to assess for glaucomatous damage in differing population groups.
Knight, O’Rese J.; Girkin, Christopher A.; Budenz, Donald L.; Durbin, Mary K.; Feuer, William J.
2017-01-01
Objective To determine the effect of race, demographic, and ocular variables on optic nerve head and retinal nerve fiber layer (RNFL) thickness measurements using spectral-domain optical coherence tomography. Methods In a cross-sectional observational study, 284 normal subjects aged 18 to 84 years were evaluated at 7 sites using Cirrus HD-OCT. Disc area, rim area, average cup-disc ratio, vertical cup-disc ratio, cup volume, and average, temporal, superior, nasal, and inferior RNFL thicknesses were calculated. The main outcome measures were associations between Cirrus HD-OCT optic nerve head and RNFL measurements and age, sex, and race. Results The 284 subjects self-identified as being of European (122), Chinese (63), African (51), or Hispanic (35) descent. After adjusting for the effect of age, there was a statistically significant difference among racial groups for all optic nerve head and RNFL parameters (all P≤.005) except rim area (P=.22). Rim area, average cup-disc ratio, vertical cup-disc ratio, and cup volume were moderately associated with disc area (r2=0.15, 0.33, 0.33, and 0.37, respectively). After a linear adjustment for disc area, there was no statistically significant difference among racial groups for any optic nerve head parameter. Individuals of European descent had thinner RNFL measurements except in the temporal quadrant. Conclusions There are racial differences in optic disc area, average cup-disc ratio, vertical cup-disc ratio, cup volume, and RNFL thickness as measured by Cirrus HD-OCT. These differences should be considered when using Cirrus HD-OCT to assess for glaucomatous damage in differing population groups. PMID:22411660
Vogel, Danny; Rathay, Andreas; Teufel, Stephanie; Ellenrieder, Martin; Zietz, Carmen; Sander, Manuela; Bader, Rainer
2017-01-01
In THA a sufficient primary implant stability is the precondition for successful secondary stability. Industrial foams of different densities have been used for primary stability investigations. The aim of this study was to analyse and compare the insertion behaviour of threaded and press-fit cups in vivo and ex vivo using bone substitutes with various densities. Two threaded (Bicon Plus®, Trident® TC) and one press-fit cup (Trident PSL®) were inserted by orthopaedic surgeons (S1, S2) into 10, 20 and 31 pcf blocks, using modified surgical instruments allowing measurements of the insertion forces and torques. Furthermore, the insertion behaviour of two cups were analysed intraoperatively. Torques for the threaded cups increased while bone substitute density increased. Maximum insertion torques were observed for S2 with 102 Nm for the Bicon Plus® in 20 pcf blocks and 77 Nm for the Trident® TC in 31 pcf blocks, which compares to the in vivo measurement (85 Nm). The average insertion forces for the press-fit cup varied from 5.2 to 6.8 kN (S1) and 7.2-11.5 kN (S2) ex vivo. Intraoperatively an average insertion force of 8.0 kN was determined. Implantation behaviour was influenced by acetabular cup design, bone substitute and experience of the surgeon. No specific density of bone substitute could be favoured for ex vivo investigations on the implantation behaviour of acetabular cups. The use synthetic bone blocks of high density (31 pcf) led to problems regarding cup orientation and seating. Therefore, bone substitutes used should be critically scrutinized in terms of the comparability to the in vivo situation.
Tabata, Tomonori; Kaku, Nobuhiro; Hara, Katsutoshi; Tsumura, Hiroshi
2015-04-01
Press-fit and screw fixation are important technical factors to achieve initial stability of a cementless acetabular cup for good clinical results of total hip arthroplasty. However, how these factors affect one another in initial cup fixation remains unclear. Therefore, this study aimed to evaluate the mutual influence between press-fit and screw fixation on initial cup stability. Foam bone was subjected to exact hemispherical-shape machining to diameters of 48, 48.5 and 49 mm. A compressive force was applied to ensure seating of a 48-mm-diameter acetabular cup in the foam bone prior to testing. Screws were inserted in six different conditions and tightened in a radial direction at the same torque strength. Then, the socket was rotated with a twist-testing machine, and the torque value at the start of axial rotation between the socket and the foam bone was measured under each screw condition. The torque values for the 48-mm-diameter reaming were >20 N m higher than those for the 48.5- and 49-mm-diameter reaming in each screw condition, indicating that press-fit fixation is stronger than screw fixation. Meanwhile, torque values for the 48.5- and 49-mm-diameter reaming tended to increase with increasing the number of screws. According to our experiment, press-fit fixation of a cementless acetabular cup achieved rigid stability. Although the supplemental screws increased stability of the implant under good press-fit conditions, they showed little impact on whole-cup stability. In the case of insufficient press-fit fixation, cup stability depends on screw stability and increasing the number of additional screws increases cup stability.
All dual mobility cups are not the same.
Aslanian, Thierry
2017-03-01
Although the natural history of dual mobility has been exclusively borne for 20 years by a single company (due to industrial ownership), the concept has undeniably been very widely popularised with nearly 40 cups on the French market which should be regarded as a weight bearing surface, both broadly and in their own right. However, within the same original idea, these implants are not all identical (design, material, fixation ect.).The aim of this work is to propose a classification of different dual mobility cups by distinguishing between thegeneral characteristics of a conventional cup and those particular to this type of implant. By comparison with a standard metal-back cup, dual mobility is based on at least one additional interface corresponding to the mobility of the polyethylene insert in the concavity of the acetabular cup called the outersurface. Design, constitutive material, fixation of the cup and characteristics of the retentive insert are analysed through the published results. The complications associated, in particular, the intraprosthetic dislocation and to a lesser extent fixation failures undoubtedly condemned the dissemination of the dual mobility concept, as witnessed by the fact that despite the precedence of this 40-year old concept, the overriding majority of publications (more than 95%) have only appeared in the last ten years. The latest generation of dual mobility cups combines: 1) a cast chrome-cobalt alloy cup covered with a bilayer coating of porous titanium and hydroxyapatite for long-term press-fit fixation to 2) an insert designed to eliminate all of the risks of intraprosthetic dislocation, whilst keeping all of the elasticity properties of the polyethylene, which has demonstrated its medium and long term effectiveness on preventing instability by overcoming other complications.
Bridgett, Rhianna; Klose, Petra; Duffield, Rob; Mydock, Suni; Lauche, Romy
2018-03-01
Despite the recent re-emergence of the process of cupping by athletes, supporting evidence for its efficacy and safety remains scarce. This systematic review aims to summarize the evidence of clinical trials on cupping for athletes. SCOPUS, Cochrane Library, PubMed, AMED, and CNKI databases were searched from their inception to December 10, 2016. Randomized controlled trials on cupping therapy with no restriction regarding the technique, or cointerventions, were included, if they measured the effects of cupping compared with any other intervention on health and performance outcomes in professionals, semi-professionals, and leisure athletes. Data extraction and risk of bias assessment using the Cochrane Risk of Bias Tool were conducted independently by two pairs of reviewers. Eleven trials with n = 498 participants from China, the United States, Greece, Iran, and the United Arab Emirates were included, reporting effects on different populations, including soccer, football, and handball players, swimmers, gymnasts, and track and field athletes of both amateur and professional nature. Cupping was applied between 1 and 20 times, in daily or weekly intervals, alone or in combination with, for example, acupuncture. Outcomes varied greatly from symptom intensity, recovery measures, functional measures, serum markers, and experimental outcomes. Cupping was reported as beneficial for perceptions of pain and disability, increased range of motion, and reductions in creatine kinase when compared to mostly untreated control groups. The majority of trials had an unclear or high risk of bias. None of the studies reported safety. No explicit recommendation for or against the use of cupping for athletes can be made. More studies are necessary for conclusive judgment on the efficacy and safety of cupping in athletes.
D, Hekmatpou; L, Moeini; S, Haji-Nadali
2013-01-01
Objective: Wet cupping is a traditional bloodletting method recommended for controlling of respiratory disease complications. This study aimed to compare the efficacy of wet cupping vs. venesection on arterial O2 saturation level of smokers. Methods: This is a randomized controlled clinical trial which started with simple sampling of smokers. After administering spirometery, participants (N = 110 male smokers) with positive pulmonary function test (PFT), who manifested Chronic Obstructive Pulmonary Disease (COPD), were randomly assigned to intervention and control groups. The two groups were assessed in terms of demographic data, rate of hemoglobin (Hb), hematocrit (Hct), and arterial O2 saturation. Then, the intervention participants underwent wet cupping whereas venesection was performed on the control participants. At four stages after the two treatments, pulse oximetery was performed. Data was analyzed using SPSS (Version 17). Results: Result shows that mean arterial O2 sat level increased at three stages, namely before, immediately after, and 6 and 12 hrs after these two treatments (p ≤ 0.001). This indicates that wet cupping and venesection alike were effective on O2 sat level in the two groups, but the increasing pattern was maintained 12 hrs afterward only in those participants who had received wet cupping (p ≤ 0.001). Moreover, the results of repeated measure ANOVA between the two groups at the four stages showed that there were significant differences between the means of O2 saturation level at the 6- and 12-hrs stages (F = 66.92, p ≤ 0.001). Conclusion: Wet cupping caused a continued O2 saturation in the intervention group even up to 12 hrs afterward. Participants expressed liveliness and improved respiration after wet cupping. Therefore, wet cupping is recommended for promoting the health of cigarette smokers. PMID:24550951
King, Nina-Marie; Lovric, Vedran; Parr, William C H; Walsh, W R; Moradi, Pouria
2017-05-01
Breast augmentation surgery poses many challenges, and meeting the patient's expectations is one of the most important. Previous reports equate 100 cc to a one-cup-size increase; however, no studies have confirmed this between commercially available bras. The aim of this study was to identify the volume increase between cup sizes across different brands and the relationship with implant selection. Five bra cup sizes from three different companies were analyzed for their volume capacity. Three methods were used to calculate the volume of the bras: (1) linear measurements; (2) volume measurement by means of water displacement; and (3) volume calculation after three-dimensional reconstruction of serial radiographic data (computed tomography). The clinical arm consisted of 79 patients who underwent breast augmentation surgery from February 1, 2014, to June 30, 2016. Answers from a short questionnaire in combination with the implant volume were analyzed. Across all three brands, the interval volume increase varied between sizes, but not all were above 100 cc. There was some variation in the volume capacity of the same cup size among the different brands. The average incremental increase in bra cup size across all three brands in the laboratory arm was 135 cc. The mean volume increase per cup size was 138.23 cc in the clinical arm. This article confirms that there is no standardization within the bra manufacturing industry. On the basis of this study, patients should be advised that 130 to 150 cc equates to a one-cup-size increase. Bras with narrower band widths need 130 cc and wider band widths require 150 cc to increase one cup size.
Yilmaz, Gonca; Caylan, Nilgun; Karacan, Can Demir; Bodur, İlknur; Gokcay, Gulbin
2014-05-01
Cup feeding has been used as an alternative feeding method for preterm infants. The purpose of this study was to determine the effect of bottle and cup feeding on exclusive breastfeeding rates at hospital discharge and 3 and 6 months post-discharge in late preterm infants. Included in the study were preterm infants of 32 to 35 weeks' gestation fed only by intermittent gastric tube at the time of recruitment; 522 infants were randomly assigned to 2 groups: the cup-fed group (n = 254) and bottle-fed group (n = 268). Main outcomes were prevalence of exclusive breastfeeding at discharge and 3 and 6 months after discharge, and length of hospital stay. Infants randomized to cup versus bottle feeding were more likely to be exclusively breastfed at discharge home (relative risk [RR], 1.58; 95% confidence interval [CI], 1.36-1.83), 3 months after discharge (RR, 1.64; 95% CI, 1.42-1.89), and 6 months after discharge (RR, 1.36; 95% CI, 1.14-1.63). There was no significant difference between groups for length of hospital stay. The mean hospital stay was 25.96 ± 2.20 days in the bottle-fed group and 25.68 ± 2.22 days in the cup-fed group. There was no significant difference between groups for time spent feeding, feeding problems, or weight gain in hospital. Cup feeding significantly increased the likelihood of late preterm infants being exclusively breastfed at discharge and 3 and 6 months after discharge, and cup feeding did not increase the length of hospital stay. Overall, we recommend cup feeding as a transitional method prior to breastfeeding for late preterm infants during hospitalization.
Lama, Daniel J; Safiullah, Shoaib; Patel, Roshan M; Lee, Thomas K; Balani, Jyoti P; Zhang, Lishi; Okhunov, Zhamshid; Margulis, Vitaly; Savage, Stephen J; Uchio, Edward; Landman, Jaime
2018-04-06
To compare the performance of 3 contemporary ureteroscopic biopsy devices for the histopathologic diagnosis of upper tract urothelial carcinoma (UTUC). We retrospectively reviewed 145 patients who underwent 182 urothelial biopsies using 2.4F backloaded cup biopsy forceps, a nitinol basket, or 3F standard cup biopsy forceps at 3 tertiary academic centers between 2011 and 2016. Experienced genitourinary pathologists provided an assessment of each specimen without knowledge of the device used for biopsy. For patients who underwent nephroureterectomy without neoadjuvant chemotherapy within 3 months of biopsy-proven UTUC diagnosis, the biopsy grade was compared with both the grade and stage of the surgical specimen. Biopsy utilization varied among the 3 institutions (P <.0001). Significant variabilities in specimen size (P = .001), the presence of intact urothelium (P = .008), and crush artifact (P = .028) were found among the biopsy devices. The quality of specimens from backloaded cup forceps was rated similarly to the nitinol basket (P >.05) and was favored over standard cup forceps specimens. Grade concordance was not affected by specimen size (P >.05), morphology (P >.1), or location (P >.5). No difference existed among the devices in the rate of acquiring a grade concordant biopsy; however, the backloaded cup forceps provided concordant biopsies that could be distinguished as low- and high-grade (P = .02). The backloaded cup forceps and nitinol basket obtained a higher quality urothelial specimen compared with standard cup forceps. Ureteroscopic biopsy device selection did not significantly impact the accuracy of the histologic diagnosis of UTUC. Copyright © 2018 Elsevier Inc. All rights reserved.
Cadossi, Matteo; Garcia, Flávio Luís; Sambri, Andrea; Andreoli, Isabella; Dallari, Dante; Pignatti, Giovanni
2017-01-01
Inadequate acetabular bone stock is a major issue in total hip arthroplasty, and several treatment options are available. Stemmed cups have been used in this scenario with variable results. A novel modular polyaxial uncemented iliac screw cup (HERM-BS-Sansone cup-Citieffe s.r.l., Calderara di Reno, Bologna, Italy) has been recently introduced to overcome the drawbacks of stemmed cups. In this retrospective study, we report the results of this cup in patients with large acetabular bone defects at 2- to 7-year follow-up. We evaluated a consecutive series of 121 hips (118 revisions and 3 complex primary arthroplasties) treated with this novel cup at a mean follow-up of 46 months. Kaplan-Meier survival analysis was performed with implant revision for any reason as a primary end point. Further survival analysis was performed excluding septic failures. Clinical outcome was assessed with the Harris Hip Score. There had been 7 reoperations: 1 for aseptic loosening, 5 for deep infection, and 1 for recurrent dislocation. In 5 cases, the cup was removed; estimated survival rate at 5-year follow-up with implant removal for any reason was 95.6% (95% confidence interval = 91-99), and 98.3% (95% CI = 96-100) excluding those failed for infection. Mean Harris Hip Score at latest follow-up was 77 points (range, 44-95; standard deviation = 11.9). The present findings show the short-term efficacy of the iliac screw cup with respect to implant survival. A longer follow-up and a larger number of patients are necessary to confirm the encouraging preliminary results. Copyright © 2016 Elsevier Inc. All rights reserved.
Suman, Devi Shankar; Wang, Yi; Unlu, Isik; Williges, Eric; Williams, Gregory M.; Gaugler, Randy
2016-01-01
Background The Asian tiger mosquito, Aedes albopictus, is a vector of dengue, Chikungunya, and Zika viruses. This mosquito inhabits a wide range of artificial water-holding containers in urban and suburban areas making it difficult to control. We tested the hypothesis that female-driven autodissemination of an insect growth regulator could penetrate cryptic oviposition habitats difficult to treat with conventional insecticidal sprays. Methodology Oviposition preferences of Ae. albopictus females for open and cryptic cups were tested in semi-field experiments. Two conventional larvicidal sprayers were tested to determine droplet penetration and larvicidal efficacy in open and cryptic habitats using Bacillus thuringiensis var. israelensis (Bti) in the field. Finally, the efficacy of pyriproxyfen autodissemination stations was assessed in cryptic and open cups in residential areas during 2013 and 2014. Principal Findings Gravid females strongly preferred cryptic (53.1±12.9 eggs/cup) over open (10.3±4.3 eggs/cup) cups for oviposition. Cryptic cups showed limited droplet penetration and produced 0.1–0.3% larval mortality with a conventional backpack and low-volume sprays of Bti. The autodissemination stations effectively contaminated these cryptic cups (59.3–84.6%) and produced 29.7–40.8% pupal mortality during 2013–2014. Significant pupal mortality was also observed in open cups. Conclusions The autodissemination station effectively exploits the oviposition behavior of wild gravid females to deliver pyriproxyfen to targeted oviposition habitats. Although the pupal mortality in cryptic cups was relatively lower than expected for the effective vector control. Autodissemination approach may be a suitable supporting tool to manage Ae. albopictus immatures in the cryptic habitats those are less accessible to conventional larvicidal sprays. PMID:28033379
Measuring Emotional Intelligence: Where We Are Today.
ERIC Educational Resources Information Center
Finegan, Jane E.
Emotional intelligence has been defined as "the ability to monitor one's own and others' feelings and emotions, to discriminate among them, and to use this information to guide one's thinking and actions" (P. Salovey and J. Mayer, 1990). As a subset of social intelligence and of personal intelligences (H. Gardner, 1983), emotional…
Arm Nerve Conduction Velocity (NCV), Brain NCV, Reaction Time, and Intelligence.
ERIC Educational Resources Information Center
Reed, T. Edward; Jensen, Arthur R.
1991-01-01
Correlations among peripheral nerve conduction velocity (NCV), brain NCV, simple and choice reaction times, and a standard measure of intelligence were investigated for 200 male college students. No correlation was found between any arm NCV and the intelligence score. Neurophysiological bases of human information processing and intelligence are…
Educational Assessment Using Intelligent Systems. Research Report. ETS RR-08-68
ERIC Educational Resources Information Center
Shute, Valerie J.; Zapata-Rivera, Diego
2008-01-01
Recent advances in educational assessment, cognitive science, and artificial intelligence have made it possible to integrate valid assessment and instruction in the form of modern computer-based intelligent systems. These intelligent systems leverage assessment information that is gathered from various sources (e.g., summative and formative). This…
Intelligence-Driven Border Security: A Promethean View of U.S. Border Patrol Intelligence Operations
2015-12-01
USBP agent, intelligence ( BPA -I), information sharing, capability gap analysis process (CGAP), Tucson Sector Red Team 15. NUMBER OF PAGES 109 16...27 2. BPA -I .............................................................................................28 3. BPA -I Requirements...71 APPENDIX A. PROFESSIONAL INTELLIGENCE ASSOCIATIONS— ADDITIONAL OPPORTUNITIES FOR BPA -IS
Human Intelligence: An Introduction to Advances in Theory and Research.
ERIC Educational Resources Information Center
Lohman, David F.
1989-01-01
Recent advances in three research traditions are summarized: trait theories of intelligence, information-processing theories of intelligence, and general theories of thinking. Work on fluid and crystallized abilities by J. Horn and R. Snow, mental speed, spatial visualization, cognitive psychology, artificial intelligence, and the construct of…
Experiential Learning Using QlikView Business Intelligence Software
ERIC Educational Resources Information Center
Podeschi, R. J.
2015-01-01
This paper reports on the use of QlikView business intelligence software for use in a Business Intelligence (BI) course within an undergraduate information systems program. The course provides students with concepts related to data warehousing, data mining, visualizations, and software tools to provide business intelligence solutions for decision…
Revisiting the Psychology of Intelligence Analysis: From Rational Actors to Adaptive Thinkers
ERIC Educational Resources Information Center
Puvathingal, Bess J.; Hantula, Donald A.
2012-01-01
Intelligence analysis is a decision-making process rife with ambiguous, conflicting, irrelevant, important, and excessive information. The U.S. Intelligence Community is primed for psychology to lend its voice to the "analytic transformation" movement aimed at improving the quality of intelligence analysis. Traditional judgment and decision making…
Carcinoma of Unknown Primary—Patient Version
Carcinoma of unknown primary (CUP) occurs when cancer cells have spread in the body and formed metastatic tumors but the site of the primary cancer is not known. There are a number of reasons why the primary cancer may not be found. Start here to find treatment information for carcinoma of unknown primary.