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Sample records for intense longitudinal retreatment

  1. Intensive training induces longitudinal changes in meditation state-related EEG oscillatory activity

    PubMed Central

    Saggar, Manish; King, Brandon G.; Zanesco, Anthony P.; MacLean, Katherine A.; Aichele, Stephen R.; Jacobs, Tonya L.; Bridwell, David A.; Shaver, Phillip R.; Rosenberg, Erika L.; Sahdra, Baljinder K.; Ferrer, Emilio; Tang, Akaysha C.; Mangun, George R.; Wallace, B. Alan; Miikkulainen, Risto; Saron, Clifford D.

    2012-01-01

    The capacity to focus one's attention for an extended period of time can be increased through training in contemplative practices. However, the cognitive processes engaged during meditation that support trait changes in cognition are not well characterized. We conducted a longitudinal wait-list controlled study of intensive meditation training. Retreat participants practiced focused attention (FA) meditation techniques for three months during an initial retreat. Wait-list participants later undertook formally identical training during a second retreat. Dense-array scalp-recorded electroencephalogram (EEG) data were collected during 6 min of mindfulness of breathing meditation at three assessment points during each retreat. Second-order blind source separation, along with a novel semi-automatic artifact removal tool (SMART), was used for data preprocessing. We observed replicable reductions in meditative state-related beta-band power bilaterally over anteriocentral and posterior scalp regions. In addition, individual alpha frequency (IAF) decreased across both retreats and in direct relation to the amount of meditative practice. These findings provide evidence for replicable longitudinal changes in brain oscillatory activity during meditation and increase our understanding of the cortical processes engaged during meditation that may support long-term improvements in cognition. PMID:22973218

  2. The estimate and measurement of longitudinal wave intensity

    NASA Astrophysics Data System (ADS)

    Ruisen, Ming

    1996-08-01

    Quasi-longitudinal waves are one type of structural waves, which are important at high frequencies. This paper studies the estimate theory and measurement technique of quasi-longitudinal waves, analyzes the bias error due to the effect of bending waves. In a two-dimensional quasi-longitudinal wave field, the intensity vector is the sum of the effective intensity vector and the intensity variation vector. Its axial component is proportional to two imaginary parts of cross spectral densities and in the measurement, it is measured by a pair of two-transducer arrays. In a onedimensional quasi-longitudinal wave field, the intensity variation is zero, the intensity is proportional to only one imaginary part of a cross spectral density and it can be measured using a two-transducer array. If bending and quasi-longitudinal waves coexist and the contribution from bending waves cannot be eliminated or reduced to a certain extent, the measured quasi-longitudinal wave intensity will contain a large error. The results measured on the three-beam structure show that quasi-longitudinal wave intensity can be accurately measured using the intensity technique when bending waves are negligible in comparison with quasi-longitudinal waves.

  3. Longitudinal Control of Intense Charged Particle Beams

    DTIC Science & Technology

    2011-01-01

    contained using longitudinal focusing, I have shown that errors in the applied focusing fields induce space-charge waves at the bunch edges that...profile along the bunch length. When the bunch is contained using longitudinal focusing, I have shown that errors in the applied focusing fields ...90 5.1.1 Beam Expansion without Longitudinal Containment................................ 90 5.1.2 Application of Focusing Fields

  4. Transverse-longitudinal coupling in intense beams

    SciTech Connect

    Wang, T.S.F.; Smith, L.

    1981-03-01

    The coupling between transverse and longitudinal perturbations is studied self-consistently by considering a beam of K-V distribution. The analysis is carried out within the context of linearized Vlasov-Maxwell equations and electrostatic approximation. The perturbation is assumed to be azimuthally symmetric but axially non-uniform (k/sub z/ is not equal to 0). It is shown that the coupling affects both the longitudinal and transverse modes significantly in the high density and low frequency region. Two new classes of longitudinal modes are found which would not exist if the transverse motions of particles are neglected. The effect of resistive wall impedance on beam stability is also studied. It is found that the longitudinal impedance can cause the transverse modes also to be weakly unstable.

  5. Retreat, Hell!

    ERIC Educational Resources Information Center

    Sims, Wil

    1978-01-01

    Describes an annual fall retreat for junior college newspaper staffs, which involves a program of workshops and discussions about problems, goals, and staff members' roles; offers advice on planning such a retreat. (GW)

  6. Time Resolved Imaging of Longitudinal Modulations in Intense Beams

    NASA Astrophysics Data System (ADS)

    Tian, Kai

    2007-11-01

    The longitudinal evolution of high intensity beams is not well understood despite its importance to the success of such applications as free electron lasers and light sources, heavy ion inertial fusion, and high energy colliders. For example any amplification of current modulations in an FEL photoinjector can lead to unwanted coherent synchrotron radiation further downstream in compression chicanes or bends. A significant factor usually neglected is the coupling to the transverse dynamics which can strongly affect the longitudinal evolution. Previous experiments at the University of Maryland have revealed much about the longitudinal physics of space-charge dominated beams by monitoring the evolution of longitudinal perturbations. For the first time, experimental results are presented here which reveal the effect of longitudinal perturbations on the transverse beam distribution, with the aid of several new diagnostics that capture detailed time-resolved density images. A longitudinal modulation of the particle density is deliberately generated at the source, and its evolution is tracked downstream using a number of diagnostics such as current monitors, high-resolution energy analyzers, as well as the transverse imaging devices. The latter consist of a high-resolution 16-bit gated camera coupled with very fast emitters such as prompt optical transition radiation (OTR) from an alumina screen, or fast Phosphor screens with 3-ns time resolution. Simulations using the particle-in-cell code WARP are applied to cross-check the experimental results. These experiments and especially the comparisons to simulation represent significant progress towards understanding the longitudinal physics of intense beams.

  7. Exploring Intensive Longitudinal Measures of Student Engagement in Blended Learning

    ERIC Educational Resources Information Center

    Henrie, Curtis R.; Bodily, Robert; Manwaring, Kristine C.; Graham, Charles R.

    2015-01-01

    In this exploratory study we used an intensive longitudinal approach to measure student engagement in a blended educational technology course, collecting both self-report and observational data. The self-report measure included a simple survey of Likert-scale and open-ended questions given repeatedly during the semester. Observational data were…

  8. The radial and longitudinal dependence of SEP intensities and fluences

    NASA Astrophysics Data System (ADS)

    Li, G.; Zank, G.; Verkhoglyadova, O.; Ruzmaikin, A.; Feynman, J.; Jun, I.

    Solar Energetic Particles SEPs are an important hazard in the context of space weather These particles bombard spacecraft and can cause instruments onboard to malfunction At sufficiently high energies and dosages they can also be extremely harmful to biological materials human bodies and are therefore one of the major safety concerns for the future manned spacecraft program We now know that these particles are associated with Coronal Mass Ejection CMEs driven shocks As a CME-driven shock propagates outward particles are injected and accelerated at the shock front via a first order Fermi mechanism aka diffusive shock acceleration After being accelerated the particles convect with the shock diffuse both upstream and downstream of the shock and many eventually escape the shock complex after reaching far upstream downstream In this work we present a model calculation of the SEP time intensity profile The model is based on a 2D-ZEUS MHD code which is used to simulate the solar wind The shock is modeled using a shell model where particle convection and diffusion are followed numerically When particles reach some distance ahead of the shock they are can escape from the shock Their subsequent motion is followed using a Monte-Carlo approach This sophisticated model allows us to obtain a time intensity profile and instantaneous particle spectra at various locations We will discuss the radial and longitudinal dependence of both the intensities and fluences

  9. Sea Ice Retreat and its Impact on the Intensity of Open-Ocean Convection in the Greenland and Iceland Seas

    NASA Astrophysics Data System (ADS)

    Moore, K.; Våge, K.; Pickart, R. S.; Renfrew, I.

    2016-02-01

    The air-sea transfer of heat and freshwater plays a critical role in the global climate system. This is particularly true for the Greenland and Iceland Seas, where these fluxes drive ocean convection that contributes to Denmark Strait Overflow Water, the densest component of the lower limb of the Atlantic Meridional Overturning Circulation (AMOC). This buoyancy transfer is most pronounced during the winter downstream of the ice edge, where the cold and dry Arctic air first comes in contact with the relatively warm ocean surface. Here we show that the wintertime retreat of sea ice in the region, combined with different rates of warming for the atmosphere and sea surface of the Greenland and Iceland Seas, has resulted in statistically significant reductions of approximately 20% in the magnitude of the winter air-sea heat fluxes since 1979. Furthermore, it is demonstrated that modes of climate variability other than the North Atlantic Oscillation (NAO) are required to fully characterize the regional air-sea interaction in this region. Mixed-layer model simulations imply that a continued decrease in atmospheric forcing will exceed a threshold for the Greenland Sea whereby convection will become depth limited, reducing the ventilation of mid-depth waters in the Nordic Seas. In the Iceland Sea, further reductions have the potential to decrease the supply of the densest overflow waters to the AMOC.

  10. Correction of differential intensity inhomogeneity in longitudinal MR images.

    PubMed

    Lewis, Emma B; Fox, Nicholas C

    2004-09-01

    Longitudinal MR imaging is increasingly being used to measure cerebral atrophy progression in dementia and other neurological disorders. Differences in intensity inhomogeneity between serial scans can confound these measurements. This differential bias also distorts nonlinear registration and makes both manual and automated segmentation of tissue type less reliable. A technique is described for the correction of this differential bias that makes no assumptions about signal distribution, bias field or signal homogeneity. Instead, the bias field calculation is performed on the basis that the remaining structure in the difference image of registered serial scans has small-scale structure. The differential bias field is of much larger scale and can thus be obtained by applying an appropriate filter to the difference image. The serial scan pair is then corrected for the differential bias field and atrophy measurement can be performed on the corrected scan pair. Application of a known, simulated bias field to real serial MR images was shown to alter atrophy measurements significantly. The differential correction method recovered the applied differential bias field and thereby improved atrophy measurements. This method was then applied to serial imaging in patients with dementia using a set of serial scan pairs with visually identified, significant differential bias and a set of scan pairs with negligible differential bias. Differential bias correction specifically reduced the variance of the atrophy measure significantly for the scans with significant differential bias.

  11. Analytical Solutions for the Nonlinear Longitudinal Drift Compression (Expansion) of Intense Charged Particle Beams

    SciTech Connect

    Edward A. Startsev; Ronald C. Davidson

    2004-04-09

    To achieve high focal spot intensities in heavy ion fusion, the ion beam must be compressed longitudinally by factors of ten to one hundred before it is focused onto the target. The longitudinal compression is achieved by imposing an initial velocity profile tilt on the drifting beam. In this paper, the problem of longitudinal drift compression of intense charged particle beams is solved analytically for the two important cases corresponding to a cold beam, and a pressure-dominated beam, using a one-dimensional warm-fluid model describing the longitudinal beam dynamics.

  12. A dynamic trajectory class model for intensive longitudinal categorical outcome.

    PubMed

    Lin, Haiqun; Han, Ling; Peduzzi, Peter N; Murphy, Terrence E; Gill, Thomas M; Allore, Heather G

    2014-07-10

    This paper presents a novel dynamic latent class model for a longitudinal response that is frequently measured as in our prospective study of older adults with monthly data on activities of daily living for more than 10 years. The proposed method is especially useful when the longitudinal response is measured much more frequently than other relevant covariates. The trajectory classes are latent classes that represent distinct temporal patterns of the longitudinal response wherein an individual may remain in a trajectory class or switch to another as the class membership predictors are updated periodically over time. The identification of a common set of trajectory classes allows changes among the temporal patterns to be distinguished from local fluctuations in the response. Within a trajectory class, the longitudinal response is modeled by a class-specific generalized linear mixed model. An informative event such as death is jointly modeled by class-specific probability of the event through shared random effects with that for the longitudinal response. We do not impose the conditional independence assumption given the classes. We illustrate the method by analyzing the change over time in activities of daily living trajectory class among 754 older adults with 70,500 person-months of follow-up in the Precipitating Events Project. We also investigate the impact of jointly modeling the class-specific probability of the event on the parameter estimates in a simulation study. The primary contribution of our paper is the periodic updating of trajectory classes for a longitudinal categorical response without assuming conditional independence.

  13. A Repeated Trajectory Class Model for Intensive Longitudinal Categorical Outcome

    PubMed Central

    Lin, Haiqun; Han, Ling; Peduzzi, Peter N.; Murphy, Terrence E.; Gill, Thomas M.; Allore, Heather G.

    2014-01-01

    This paper presents a novel repeated latent class model for a longitudinal response that is frequently measured as in our prospective study of older adults with monthly data on activities of daily living (ADL) for more than ten years. The proposed method is especially useful when the longitudinal response is measured much more frequently than other relevant covariates. The repeated trajectory classes represent distinct temporal patterns of the longitudinal response wherein an individual’s membership in the trajectory classes may renew or change over time. Within a trajectory class, the longitudinal response is modeled by a class-specific generalized linear mixed model. Effectively, an individual may remain in a trajectory class or switch to another as the class membership predictors are updated periodically over time. The identification of a common set of trajectory classes allows changes among the temporal patterns to be distinguished from local fluctuations in the response. An informative event such as death is jointly modeled by class-specific probability of the event through shared random effects. We do not impose the conditional independence assumption given the classes. The method is illustrated by analyzing the change over time in ADL trajectory class among 754 older adults with 70500 person-months of follow-up in the Precipitating Events Project. We also investigate the impact of jointly modeling the class-specific probability of the event on the parameter estimates in a simulation study. The primary contribution of our paper is the periodic updating of trajectory classes for a longitudinal categorical response without assuming conditional independence. PMID:24519416

  14. Mean-field thalamocortical modeling of longitudinal EEG acquired during intensive meditation training.

    PubMed

    Saggar, Manish; Zanesco, Anthony P; King, Brandon G; Bridwell, David A; MacLean, Katherine A; Aichele, Stephen R; Jacobs, Tonya L; Wallace, B Alan; Saron, Clifford D; Miikkulainen, Risto

    2015-07-01

    Meditation training has been shown to enhance attention and improve emotion regulation. However, the brain processes associated with such training are poorly understood and a computational modeling framework is lacking. Modeling approaches that can realistically simulate neurophysiological data while conforming to basic anatomical and physiological constraints can provide a unique opportunity to generate concrete and testable hypotheses about the mechanisms supporting complex cognitive tasks such as meditation. Here we applied the mean-field computational modeling approach using the scalp-recorded electroencephalogram (EEG) collected at three assessment points from meditating participants during two separate 3-month-long shamatha meditation retreats. We modeled cortical, corticothalamic, and intrathalamic interactions to generate a simulation of EEG signals recorded across the scalp. We also present two novel extensions to the mean-field approach that allow for: (a) non-parametric analysis of changes in model parameter values across all channels and assessments; and (b) examination of variation in modeled thalamic reticular nucleus (TRN) connectivity over the retreat period. After successfully fitting whole-brain EEG data across three assessment points within each retreat, two model parameters were found to replicably change across both meditation retreats. First, after training, we observed an increased temporal delay between modeled cortical and thalamic cells. This increase provides a putative neural mechanism for a previously observed reduction in individual alpha frequency in these same participants. Second, we found decreased inhibitory connection strength between the TRN and secondary relay nuclei (SRN) of the modeled thalamus after training. This reduction in inhibitory strength was found to be associated with increased dynamical stability of the model. Altogether, this paper presents the first computational approach, taking core aspects of physiology and

  15. Longitudinal confinement and matching of an intense electron beam

    NASA Astrophysics Data System (ADS)

    Beaudoin, B.; Haber, I.; Kishek, R. A.; Bernal, S.; Koeth, T.; Sutter, D.; O'Shea, P. G.; Reiser, M.

    2011-01-01

    An induction cell has successfully been demonstrated to longitudinally confine a space-charge dominated bunch for over a thousand turns (>11.52 km) in the University of Maryland Electron Ring [Haber et al., Nucl. Instrum. Methods Phys. Res. A 606, 64 (2009) and R. A. Kishek et al., Int. J. Mod. Phys. A 22, 3838 (2007)]. With the use of synchronized periodic focusing fields, the beam is confined for multiple turns overcoming the longitudinal space-charge forces. Experimental results show that an optimum longitudinal match is obtained when the focusing frequency for containment of the 0.52 mA beam is applied at every fifth turn. Containment of the beam bunch is achievable at lower focusing frequencies, at the cost of a reduction in the transported charge from the lack of sufficient focusing. Containment is also obtainable, if the confinement fields overfocus the bunch, exciting multiple waves at the bunch ends, which propagate into the central region of the beam, distorting the overall constant current beam shape.

  16. Longitudinal confinement and matching of an intense electron beam

    SciTech Connect

    Beaudoin, B.; Haber, I.; Kishek, R. A.; Bernal, S.; Koeth, T.; Sutter, D.; O'Shea, P. G.; Reiser, M.

    2011-01-15

    An induction cell has successfully been demonstrated to longitudinally confine a space-charge dominated bunch for over a thousand turns (>11.52 km) in the University of Maryland Electron Ring [Haber et al., Nucl. Instrum. Methods Phys. Res. A 606, 64 (2009) and R. A. Kishek et al., Int. J. Mod. Phys. A 22, 3838 (2007)]. With the use of synchronized periodic focusing fields, the beam is confined for multiple turns overcoming the longitudinal space-charge forces. Experimental results show that an optimum longitudinal match is obtained when the focusing frequency for containment of the 0.52 mA beam is applied at every fifth turn. Containment of the beam bunch is achievable at lower focusing frequencies, at the cost of a reduction in the transported charge from the lack of sufficient focusing. Containment is also obtainable, if the confinement fields overfocus the bunch, exciting multiple waves at the bunch ends, which propagate into the central region of the beam, distorting the overall constant current beam shape.

  17. Longitudinal intensity distribution near the focus produced by light through scattering media

    NASA Astrophysics Data System (ADS)

    Ji, Xuan-Xuan; Wan, Li-Peng; Chen, Zi-Yang; Pu, Ji-Xiong

    2017-08-01

    Speckle pattern is formed when coherent light passes through scattering media. It has been demonstrated that after appropriately optimizing the phase of the incident light, a bright focal spot in the target point can be obtained for the case that the light passes through the scattering medium. However, until now the focused intensity distribution near the focus seems unclear. In this paper we experimentally investigate some factors influencing the longitudinal intensity distribution near the focus in details. It is shown that the desired longitudinal focused intensity distribution can be obtained by optimizing the incident light. The results may have potential applications in particle manipulation and laser processing, etc.

  18. Longitudinal Density Modulation and Energy Conversion in Intense Beams

    SciTech Connect

    Harris, J; Neumann, J; Tian, K; O'Shea, P

    2006-02-17

    Density modulation of charged particle beams may occur as a consequence of deliberate action, or may occur inadvertently because of imperfections in the particle source or acceleration method. In the case of intense beams, where space charge and external focusing govern the beam dynamics, density modulation may under some circumstances be converted to velocity modulation, with a corresponding conversion of potential energy to kinetic energy. Whether this will occur depends on the properties of the beam and the initial modulation. This paper describes the evolution of discrete and continuous density modulations on intense beams, and discusses three recent experiments related to the dynamics of density-modulated electron beams.

  19. Revisiting the Longitudinal 90° Limit in High Intensity Linear Accelerators.

    PubMed

    Hofmann, Ingo; Boine-Frankenheim, Oliver

    2017-03-17

    Parametric envelope and sum envelope resonances are analyzed to revisit the validity of an assumed stop band and design limit of high intensity linear accelerators at a longitudinal phase advance of 90° per focusing lattice period. While the 90° limit is unquestioned in the transverse plane, we show here that it can be dropped as longitudinal limit for lattices with two or more rf gaps per focusing period. A new limit arises, however, from a novel transverse-longitudinal parametric sum envelope instability. The resulting sum instability rule allows the phase advance to exceed 90° longitudinally provided that transversely it remains correspondingly under 90°. We suggest that the additional design freedom opens the possibility for larger accelerating gradients and stronger longitudinal focusing with potential length and cost saving in the design of advanced superconducting linear accelerator concepts-as long as technological cavity limits are not reached.

  20. Revisiting the Longitudinal 90° Limit in High Intensity Linear Accelerators

    NASA Astrophysics Data System (ADS)

    Hofmann, Ingo; Boine-Frankenheim, Oliver

    2017-03-01

    Parametric envelope and sum envelope resonances are analyzed to revisit the validity of an assumed stop band and design limit of high intensity linear accelerators at a longitudinal phase advance of 90° per focusing lattice period. While the 90° limit is unquestioned in the transverse plane, we show here that it can be dropped as longitudinal limit for lattices with two or more rf gaps per focusing period. A new limit arises, however, from a novel transverse-longitudinal parametric sum envelope instability. The resulting sum instability rule allows the phase advance to exceed 90° longitudinally provided that transversely it remains correspondingly under 90°. We suggest that the additional design freedom opens the possibility for larger accelerating gradients and stronger longitudinal focusing with potential length and cost saving in the design of advanced superconducting linear accelerator concepts—as long as technological cavity limits are not reached.

  1. Breaking of relativistically intense longitudinal space charge waves: A description using Dawson sheet model

    NASA Astrophysics Data System (ADS)

    Sengupta, Sudip

    2014-02-01

    Spatio-temporal evolution of relativistically intense longitudinal space charge waves in a cold homogeneous plasma is studied analytically as well as numerically, as an initial value problem, using Dawson sheet model. It is found that, except for very special initial conditions which generates the well known longitudinal Akhiezer-Polovin mode, for all other initial conditions, the waves break through a novel mechanism called phase mixing at an amplitude well below the Akhiezer-Polovin limit. An immediate consequence of this is, that Akhiezer-Polovin waves break when subjected to arbitrarily small longitudinal perturbations. We demonstrate this by performing extensive numerical simulations. This result may be of direct relevance to ultrashort, ultraintense laser/beam pulse-plasma interaction experiments where relativistically intense waves are routinely excited.

  2. Breaking of relativistically intense longitudinal space charge waves: A description using Dawson sheet model

    SciTech Connect

    Sengupta, Sudip

    2014-02-11

    Spatio-temporal evolution of relativistically intense longitudinal space charge waves in a cold homogeneous plasma is studied analytically as well as numerically, as an initial value problem, using Dawson sheet model. It is found that, except for very special initial conditions which generates the well known longitudinal Akhiezer-Polovin mode, for all other initial conditions, the waves break through a novel mechanism called phase mixing at an amplitude well below the Akhiezer-Polovin limit. An immediate consequence of this is, that Akhiezer-Polovin waves break when subjected to arbitrarily small longitudinal perturbations. We demonstrate this by performing extensive numerical simulations. This result may be of direct relevance to ultrashort, ultraintense laser/beam pulse-plasma interaction experiments where relativistically intense waves are routinely excited.

  3. Poisson Growth Mixture Modeling of Intensive Longitudinal Data: An Application to Smoking Cessation Behavior

    ERIC Educational Resources Information Center

    Shiyko, Mariya P.; Li, Yuelin; Rindskopf, David

    2012-01-01

    Intensive longitudinal data (ILD) have become increasingly common in the social and behavioral sciences; count variables, such as the number of daily smoked cigarettes, are frequently used outcomes in many ILD studies. We demonstrate a generalized extension of growth mixture modeling (GMM) to Poisson-distributed ILD for identifying qualitatively…

  4. Single-pulse and multipulse longitudinal phase space and temperature measurements of an intense ion beam

    NASA Astrophysics Data System (ADS)

    Coleman, J. E.; Seidl, P. A.; Bieniosek, F. M.; Leitner, M. A.; Lidia, S. M.; Vay, J. L.; Waldron, W. L.; Grote, D. P.; Welch, D. R.

    2012-07-01

    Longitudinal phase space and temperature measurements were conducted on a 2-3μs long, singly charged K+ ion bunch with an ion energy of ˜0.3MeV and current of 30 mA. The principal objective of these experiments was to measure the longitudinal beam dynamics and study the limits of axial compression. The differences between the measured beam energy, longitudinal beam dynamics, and the amplitude and time history of the Marx voltage waveform were all quantified. Longitudinal phase space measurements indicate a slight chromaticity (<1%) in the beam from head to tail. Record low longitudinal temperatures of Tz=2-4×10-2eV were measured for a beam bunch of this intensity with negligible effects from neutralizing the beam space charge with a background plasma. A qualitative comparison of experimental and calculated results are presented, which include time resolved longitudinal distributions, and phase space of the beam at 430 cm.

  5. Long path-length experimental studies of longitudinal phenomena in intense beams

    SciTech Connect

    Beaudoin, B. L.; Haber, I.; Kishek, R. A.; Bernal, S.; Koeth, T. W.

    2016-05-15

    Intense charged particle beams are nonneutral plasmas as they can support a host of plasma waves and instabilities. The longitudinal physics, for a long beam, can often be reasonably described by a 1-D cold-fluid model with a geometry factor to account for the transverse effects. The plasma physics of such beams has been extensively studied theoretically and computationally for decades, but until recently, the only experimental measurements were carried out on relatively short linacs. This work reviews experimental studies over the past five years on the University of Maryland Electron Ring, investigating longitudinal phenomena over time scales of thousands of plasma periods, illustrating good agreement with simulations.

  6. Towards a new orientation: a qualitative longitudinal study of an intensive care recovery programme.

    PubMed

    Jensen, Janet F; Overgaard, Dorthe; Bestle, Morten H; Christensen, Doris F; Egerod, Ingrid

    2017-01-01

    To describe the patient experience of ICU recovery from a longitudinal perspective by analysing follow-up consultations at three time-points. After a stay in the intensive care unit, patients risk physical and psychological problems during recovery. Follow-up after intensive care has emerged to aid psychological recovery, and improve health-related quality of life. More insight is needed into the mechanisms of intensive care recovery. A descriptive multicenter longitudinal qualitative design. A subsample of 36 consultations with 12 patients strategically selected from a randomised controlled trial on intensive care recovery from 10 Danish intensive care units. Data were generated during an ICU recovery programme including three consultations (at 1-3, 4-5, 9-11 months). First consultation was face-to-face using patient photographs to aid memory. Second and third consultations were by telephone using reflection sheets to focus dialogue. Thematic analysis and narrative theory were used to explore mechanisms of recovery using audio-recordings of consultations, patient photographs and reflection sheets as the sources of data. The basic narrative of recovery was 'toward a trajectory of new orientation'. This narrative contained the chronological narratives of being 'at death's door', 'still not out of the woods' and 'on the road to recovery'. The road to recovery was described as downhill, steady-state or progressive. New orientation was obtained in steady-state or progressive recovery. This study provides a contemporary understanding of the process of intensive care recovery. Recovery evolves through narratives of mortal danger, risk of relapse and moving forward towards a new orientation in life. These findings enable health care professionals to understand what patients experience during stages of recovery. This is important to improve health care professionals in the assessment of long-term outcome, and management of patients after intensive care. © 2016 John Wiley

  7. Longitudinal oscillation of intensity fronts in a strand at the edge of an active region

    SciTech Connect

    Guo, L.-J.; Tu, C.-Y.; He, J.-S.; Marsch, E.

    2010-03-25

    The edge of a solar active region (AR) is considered as a possible source region of the slow solar wind. Winebarger et al.(2001) observed outflows from an AR with velocities between 5 and 20 km/s. Recently, Sakao et al.(2007) reported the outflow of X-ray-emitting plasma from the edge of an AR. This outflow was inferred from the observation of outward traveling intensity enhancements. However, in Robbrecht et al.(2001), propagation of slow magnetoacoustic waves along the strand was considered as the possible cause for the longitudinal extension of the strand. Whether this phenomenon relates to a slow-mode wave or the outflow of plasma or a heating process of different parts of the strand is still an open question. Here we try to identify the nature of such a traveling event through studying the longitudinal motions of certain intensity level fronts in the strand. We find that the intensity front is oscillating like a sinusoidal signal along the strand with a period of 11 minutes. This result suggests that the oscillation might be partly related with the 5-minute p-mode oscillation in the photosphere. Moreover, we find that such oscillation of intensity-level fronts can be described by a model in which the strand has periodic extension. Yet, the relation between the extending strand and slow solar wind needs to be further studied.

  8. Long-path-length experimental studies of longitudinal phenomena in intense beams

    NASA Astrophysics Data System (ADS)

    Beaudoin, Brian

    2015-11-01

    Intense charged particle beams are nonneutral plasmas and they can support a host of plasma waves and instabilities. For a long beam bunch, the longitudinal physics can often be reasonably described by a 1-D cold-fluid model, with a geometry factor to account for the transverse effects. The plasma physics of such beams has been extensively studied theoretically and computationally for decades, but until recently, the only experimental measurements were carried out on relatively short linacs. This work reviews experimental studies over the past 5 years on the U. Maryland Electron Ring, investigating longitudinal phenomena, for the first time, over time scales of hundreds and thousands of plasma periods. These results are in good agreement with theory and simulation. Topics that will be discussed are: Longitudinal confinement of a long bunch using barrier fields. The generation of space charge waves from barrier field mismatches, their propagation along the bunch and reflection at the beam ends, as well as their long-term dissipation. The characterization of solitary waves from density/velocity perturbations in the center of the bunch. Compression of solitary wave trains with velocity ``tilts'' (head-to-tail gradient). Observation of a multi-stream instability driven by the longitudinal merging of bunches and the characterization of the onset of the instability with a PIC code. The shock-wave compression of a bunch using rapidly-moving barrier fields.

  9. Simulating Longitudinal Brain MRIs with Known Volume Changes and Realistic Variations in Image Intensity

    PubMed Central

    Khanal, Bishesh; Ayache, Nicholas; Pennec, Xavier

    2017-01-01

    This paper presents a simulator tool that can simulate large databases of visually realistic longitudinal MRIs with known volume changes. The simulator is based on a previously proposed biophysical model of brain deformation due to atrophy in AD. In this work, we propose a novel way of reproducing realistic intensity variation in longitudinal brain MRIs, which is inspired by an approach used for the generation of synthetic cardiac sequence images. This approach combines a deformation field obtained from the biophysical model with a deformation field obtained by a non-rigid registration of two images. The combined deformation field is then used to simulate a new image with specified atrophy from the first image, but with the intensity characteristics of the second image. This allows to generate the realistic variations present in real longitudinal time-series of images, such as the independence of noise between two acquisitions and the potential presence of variable acquisition artifacts. Various options available in the simulator software are briefly explained in this paper. In addition, the software is released as an open-source repository. The availability of the software allows researchers to produce tailored databases of images with ground truth volume changes; we believe this will help developing more robust brain morphometry tools. Additionally, we believe that the scientific community can also use the software to further experiment with the proposed model, and add more complex models of brain deformation and atrophy generation. PMID:28381986

  10. Simulating Longitudinal Brain MRIs with Known Volume Changes and Realistic Variations in Image Intensity.

    PubMed

    Khanal, Bishesh; Ayache, Nicholas; Pennec, Xavier

    2017-01-01

    This paper presents a simulator tool that can simulate large databases of visually realistic longitudinal MRIs with known volume changes. The simulator is based on a previously proposed biophysical model of brain deformation due to atrophy in AD. In this work, we propose a novel way of reproducing realistic intensity variation in longitudinal brain MRIs, which is inspired by an approach used for the generation of synthetic cardiac sequence images. This approach combines a deformation field obtained from the biophysical model with a deformation field obtained by a non-rigid registration of two images. The combined deformation field is then used to simulate a new image with specified atrophy from the first image, but with the intensity characteristics of the second image. This allows to generate the realistic variations present in real longitudinal time-series of images, such as the independence of noise between two acquisitions and the potential presence of variable acquisition artifacts. Various options available in the simulator software are briefly explained in this paper. In addition, the software is released as an open-source repository. The availability of the software allows researchers to produce tailored databases of images with ground truth volume changes; we believe this will help developing more robust brain morphometry tools. Additionally, we believe that the scientific community can also use the software to further experiment with the proposed model, and add more complex models of brain deformation and atrophy generation.

  11. Shaping the longitudinal intensity pattern of Cartesian beams in lossless and lossy media

    NASA Astrophysics Data System (ADS)

    Corato-Zanarella, Mateus; Corato-Zanarella, Henrique; Zamboni-Rached, Michel

    2017-09-01

    Several applications, such as optical tweezers and atom guiding, benefit from techniques that allow the engineering of spatial field profiles, in particular their longitudinal intensity patterns. In cylindrical coordinates, methods such as frozen waves allow an advanced control of beam characteristics, but in Cartesian coordinates there is no analogous technique. Since Cartesian beams may also be useful in applications, we develop here a method to modulate on demand the longitudinal intensity pattern of any (initially) unidimensional Cartesian beam with concentrated angular spectrum (thus encompassing all unidimensional paraxial beams) in lossless and lossy media. To this end, we write the total beam as a product of two unidimensional beams and explore the degree of freedom provided by the additional Cartesian coordinate. While in the plane where this coordinate is zero the chosen unidimensional beam keeps its structure with the additional desired intensity modulation, a sinusoidal-like oscillation appears in the direction of this variable and creates a spot whose size is tunable. Examples with Gaussian and Airy beams are presented and their corresponding experimental demonstrations in free-space are performed to show the validity of the method.

  12. Participation in an Intensive Longitudinal Study with Weekly Web Surveys Over 2.5 Years

    PubMed Central

    Barber, Jennifer; Kusunoki, Yasamin; Schulz, Paul

    2016-01-01

    Background Technological advances have made it easier for researchers to collect more frequent longitudinal data from survey respondents via personal computers, smartphones, and other mobile devices. Although technology has led to an increase in data-intensive longitudinal studies, little is known about attrition from such studies or the differences between respondents who complete frequently administered surveys in a timely manner, and respondents who do not. Objective We examined respondent characteristics and behaviors associated with continued and on-time participation in a population-based intensive longitudinal study, using weekly web-based survey interviews over an extended period. Methods We analyzed data from the Relationship Dynamics and Social Life study, an intensive longitudinal study that collected weekly web-based survey interviews for 2.5 years from 1003 18- and 19-year-olds to investigate factors shaping the dynamics of their sexual behavior, contraceptive use, and pregnancies. Results Ordinary least squares and logistic regression analyses showed background respondent characteristics measured at baseline were associated with the number of days respondents remained enrolled in the study, the number of interviews they completed, and the odds that they were late completing interviews. In addition, we found that changes in pregnancy-related behaviors reported in the weekly interviews were associated with late completion of interviews. Specifically, after controlling for sociodemographic, personality, contact information, and prior experience variables, we found that weekly reports such as starting to have sex (odds ratio [OR] 1.17, 95% CI 1.03-1.32, P=.01), getting a new partner (OR 1.76, 95% CI 1.53-2.03, P<.001), stopping the use of contraception (OR 1.28, 95% CI 1.10-1.49, P=.001), and having a new pregnancy (OR 5.57, 95% CI 4.26-7.29, P<.001) were significantly associated with late survey completion. However, young women who reported changes in

  13. Longitudinal intensity oscillations in coronal loops observed with TRACE I. Overview of Measured Parameters

    NASA Astrophysics Data System (ADS)

    De Moortel, I.; Ireland, J.; Walsh, R. W.; Hood, A. W.

    2002-09-01

    In this paper we aim to give a comprehensive overview of geometric and physical properties of longitudinal oscillations in large coronal loops. The 38 examples of propagating disturbances were obtained from the analysis of high cadence, 171 Å TRACE data (JOP 83 and JOP 144). The majority of these outward propagating oscillations are found in the footpoints of large diffuse coronal loop structures, close to active regions. The disturbances travel outward with a propagation speed of the order of v≈122±43 km s-1. The variations in intensity are estimated to be roughly 4.1±1.5% of the background loop brightness. The propagating disturbances are found to be damped very quickly and are typically only detected in the first 8.9±4.4 Mm along the loop. Using a wavelet analysis, periods of the order of 282±93 s are found and the energy flux was estimated as 342±126 erg cm-2 s-1. We found highly filamentary behavior in the lower part of the coronal loops and showed that the intensity oscillations can be present for several consecutive hours, with a more or less constant period. It is evident that the longitudinal oscillations are a widespread, regularly occurring coronal phenomena. A companion paper is devoted to the interpretation and discussion of the results.

  14. Stress intensity factors for low aspect ratio longitudinal surface cracks in thin pipes

    SciTech Connect

    Wang, X.; Lambert, S.B.

    1996-12-31

    Finite element calculations of stress intensity factors for longitudinal external and internal semi-elliptical surface cracks in thin pipes (R/t of 10) and external edge cracks in thin pipes (R/t of 10, 20, 40) are presented. Constant, linear, parabolic and cubic stress distributions were applied to the crack face. Comparisons of flat plate and thin pipe stress intensity factor results are made for the deepest and surface points of the surface cracks, and for edge cracks. Recommendations are given regarding the limits of applicability of flat plate solutions. For a pipe with R/t of 10, the stress intensity factors for shallow semi-elliptical cracks and edge cracks (a/t less than 0.4) can be approximated to within 6% using the corresponding solutions for cracks in flat plates. For pipes with R/t larger than 40, the stress intensity factors for a wide range of crack depths, 0 {le} a/t {le} 0.8, can be approximated with good accuracy using the corresponding solutions for cracks in flat plates.

  15. The Adult Religious Retreat and the Higher Learning: Theory, Design, and Evaluation.

    ERIC Educational Resources Information Center

    Counelis, James Steve

    This paper presents a case study of a Christian retreat held by the Federation of Greek Orthodox Choirs of the Western States of the Diocese of San Francisco (California), March 14-06, 1986 at St. Nicholas Ranch and Retreat Center, Squaw Valley, California. The religious retreat is defined as a short-term, intensive educational program designed to…

  16. Day-to-day variations in health behaviors and daily functioning: two intensive longitudinal studies.

    PubMed

    Flueckiger, Lavinia; Lieb, Roselind; Meyer, Andrea H; Witthauer, Cornelia; Mata, Jutta

    2017-04-01

    In two intensive longitudinal studies we examined the daily dynamics in health behaviors and their associations with two important indicators of young adults' daily functioning, namely, affect and academic performance. Over a period of 8 months, university students (Study 1: N = 292; Study 2: N = 304) reported sleep, physical activity, snacking, positive and negative affect, and learning goal achievement. A subsample wore an actigraph to provide an additional measurement of sleep and physical activity and participated in a controlled laboratory snacking situation. Multilevel structural equation models showed that better day-to-day sleep quality or more physical activity than usual, but not snacking, were associated with improved daily functioning, namely, affect and learning goal achievement. Importantly, self-report measurements of health behaviors correlated with behavioral measurements. These findings have the potential to inform health promotion programs aimed at supporting young adults in their daily functioning in good physical and mental health.

  17. The importance of physical activity and sleep for affect on stressful days: Two intensive longitudinal studies.

    PubMed

    Flueckiger, Lavinia; Lieb, Roselind; Meyer, Andrea H; Witthauer, Cornelia; Mata, Jutta

    2016-06-01

    We investigated the potential stress-buffering effect of 3 health behaviors-physical activity, sleep quality, and snacking-on affect in the context of everyday life in young adults. In 2 intensive longitudinal studies with up to 65 assessment days over an entire academic year, students (Study 1, N = 292; Study 2, N = 304) reported stress intensity, sleep quality, physical activity, snacking, and positive and negative affect. Data were analyzed using multilevel regression analyses. Stress and positive affect were negatively associated; stress and negative affect were positively associated. The more physically active than usual a person was on a given day, the weaker the association between stress and positive affect (Study 1) and negative affect (Studies 1 and 2). The better than usual a person's sleep quality had been during the previous night, the weaker the association between stress and positive affect (Studies 1 and 2) and negative affect (Study 2). The association between daily stress and positive or negative affect did not differ as a function of daily snacking (Studies 1 and 2). On stressful days, increasing physical activity or ensuring high sleep quality may buffer adverse effects of stress on affect in young adults. These findings suggest potential targets for health-promotion and stress-prevention programs, which could help reduce the negative impact of stress in young adults. (PsycINFO Database Record

  18. Torsional resistance of retreatment instruments.

    PubMed

    Lopes, Hélio P; Elias, Carlos N; Vedovello, Gislaine A F; Bueno, Carlos E S; Mangelli, Marcelo; Siqueira, José F

    2011-10-01

    This study compared the torsional resistance of two brands of rotary nickel-titanium (NiTi) instruments indicated for endodontic retreatment. Mtwo retreatment instruments #15 and #25 (VDW, Munich, Germany) and ProTaper Universal retreatment instruments D2 and D3 (Maillefer/Dentsply, Ballaigues, Switzerland) were subjected to a torsional assay in clockwise rotation. The two parameters evaluated were maximum torque and angular deflection at failure. Fractured instruments had their fractured surfaces and helical shafts examined by scanning electron microscopy. The results indicated that the angular deflection at fracture decreased in the following order: Mtwo retreatment file #15 > Mtwo retreatment file #25 > ProTaper Universal retreatment file D2 > ProTaper Universal retreatment file D3. As for the maximum torque values, the results revealed the following descending order: ProTaper Universal file D2 > Mtwo retreatment file #25 > ProTaper Universal file D3 > Mtwo retreatment file #15. Scanning electron microscopic analysis revealed that plastic deformation occurred along the helical shaft of the fractured instruments. Fractured surfaces were of the ductile type. The instruments tested showed different torsional behavior depending on the parameter evaluated. If one considers that high angular deflection values may serve as a safety factor, then the Mtwo retreatment instruments showed significantly better results. Copyright © 2011 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  19. Polar Cap Retreat

    NASA Technical Reports Server (NTRS)

    2004-01-01

    13 August 2004 This red wide angle Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) image shows a view of the retreating seasonal south polar cap in the most recent spring in late 2003. Bright areas are covered with frost, dark areas are those from which the solid carbon dioxide has sublimed away. The center of this image is located near 76.5oS, 28.2oW. The scene is large; it covers an area about 250 km (155 mi) across. The scene is illuminated by sunlight from the upper left.

  20. What's in a Day? A Guide to Decomposing the Variance in Intensive Longitudinal Data

    PubMed Central

    de Haan-Rietdijk, Silvia; Kuppens, Peter; Hamaker, Ellen L.

    2016-01-01

    In recent years there has been a growing interest in the use of intensive longitudinal research designs to study within-person processes. Examples are studies that use experience sampling data and autoregressive modeling to investigate emotion dynamics and between-person differences therein. Such designs often involve multiple measurements per day and multiple days per person, and it is not clear how this nesting of the data should be accounted for: That is, should such data be considered as two-level data (which is common practice at this point), with occasions nested in persons, or as three-level data with beeps nested in days which are nested in persons. We show that a significance test of the day-level variance in an empty three-level model is not reliable when there is autocorrelation. Furthermore, we show that misspecifying the number of levels can lead to spurious or misleading findings, such as inflated variance or autoregression estimates. Throughout the paper we present instructions and R code for the implementation of the proposed models, which includes a novel three-level AR(1) model that estimates moment-to-moment inertia and day-to-day inertia. Based on our simulations we recommend model selection using autoregressive multilevel models in combination with the AIC. We illustrate this method using empirical emotion data from two independent samples, and discuss the implications and the relevance of the existence of a day level for the field. PMID:27378986

  1. Modeling Intensive Longitudinal Data With Mixtures of Nonparametric Trajectories and Time-Varying Effects

    PubMed Central

    Dziak, John J.; Li, Runze; Tan, Xianming; Shiffman, Saul; Shiyko, Mariya P.

    2015-01-01

    Behavioral scientists increasingly collect intensive longitudinal data (ILD), in which phenomena are measured at high frequency and in real time. In many such studies, it is of interest to describe the pattern of change over time in important variables as well as the changing nature of the relationship between variables. Individuals' trajectories on variables of interest may be far from linear, and the predictive relationship between variables of interest and related covariates may also change over time in a nonlinear way. Time-varying effect models (TVEMs; see Tan, Shiyko, Li, Li, & Dierker, 2012) address these needs by allowing regression coefficients to be smooth, nonlinear functions of time rather than constants. However, it is possible that not only observed covariates but also unknown, latent variables may be related to the outcome. That is, regression coefficients may change over time and also vary for different kinds of individuals. Therefore, we describe a finite mixture version of TVEM for situations in which the population is heterogeneous and in which a single trajectory would conceal important, inter-individual differences. This extended approach, MixTVEM, combines finite mixture modeling with non- or semi-parametric regression modeling, in order to describe a complex pattern of change over time for distinct latent classes of individuals. The usefulness of the method is demonstrated in an empirical example from a smoking cessation study. We provide a versatile SAS macro and R function for fitting MixTVEMs. PMID:26390169

  2. The Application of Intensive Longitudinal Methods to Investigate Change: Stimulating the Field of Applied Family Research.

    PubMed

    Bamberger, Katharine T

    2016-03-01

    The use of intensive longitudinal methods (ILM)-rapid in situ assessment at micro timescales-can be overlaid on RCTs and other study designs in applied family research. Particularly, when done as part of a multiple timescale design-in bursts over macro timescales-ILM can advance the study of the mechanisms and effects of family interventions and processes of family change. ILM confers measurement benefits in accurately assessing momentary and variable experiences and captures fine-grained dynamic pictures of time-ordered processes. Thus, ILM allows opportunities to investigate new research questions about intervention effects on within-subject (i.e., within-person, within-family) variability (i.e., dynamic constructs) and about the time-ordered change process that interventions induce in families and family members beginning with the first intervention session. This paper discusses the need and rationale for applying ILM to family intervention evaluation, new research questions that can be addressed with ILM, example research using ILM in the related fields of basic family research and the evaluation of individual-based interventions. Finally, the paper touches on practical challenges and considerations associated with ILM and points readers to resources for the application of ILM.

  3. Phase mixing of relativistically intense longitudinal wave packets in a cold plasma

    NASA Astrophysics Data System (ADS)

    Mukherjee, Arghya; Sengupta, Sudip

    2016-09-01

    Phase mixing of relativistically intense longitudinal wave packets in a cold homogeneous unmagnetized plasma has been studied analytically and numerically using the Dawson Sheet Model. A general expression for phase mixing time ( ω p t m i x ) as a function of amplitude of the wave packet (δ) and width of the spectrum ( Δ k / k ) has been derived. It is found that the phase mixing time crucially depends on the relative magnitude of amplitude "δ" and the spectral width " Δ k / k ". For Δ k / k ≤ 2 ωp 2 δ 2 / c 2 k 2 , ω p t m i x scales with δ as ˜ 1 / δ 5 , whereas for Δ k / k > 2 ωp 2 δ 2 / c 2 k 2 , ω p t m i x scales with δ as ˜ 1 / δ 3 , where ωp is the non-relativistic plasma frequency and c is the speed of light in vacuum. We have also verified the above theoretical scalings using numerical simulations based on the Dawson Sheet Model.

  4. Investigation of longitudinal proton acceleration in exploded targets irradiated by intense short-pulse laser

    SciTech Connect

    Gauthier, M.; Lévy, A.; D'Humières, E.; Beaucourt, C.; Breil, J.; Feugeas, J. L.; Nicolaï, P.; Tikhonchuk, V.; Glesser, M.; Albertazzi, B.; Chen, S. N.; Dervieux, V.; Fuchs, J.; Pépin, H.; Antici, P.

    2014-01-15

    It was recently shown that a promising way to accelerate protons in the forward direction to high energies is to use under-dense or near-critical density targets instead of solids. Simulations have revealed that the acceleration process depends on the density gradients of the plasma target. Indeed, under certain conditions, the most energetic protons are predicted to be accelerated by a collisionless shock mechanism that significantly increases their energy. We report here the results of a recent experiment dedicated to the study of longitudinal ion acceleration in partially exploded foils using a high intensity (∼5 × 10{sup 18} W/cm{sup 2}) picosecond laser pulse. We show that protons accelerated using targets having moderate front and rear plasma gradients (up to ∼8 μm gradient length) exhibit similar maximum proton energy and number compared to proton beams that are produced, in similar laser conditions, from solid targets, in the well-known target normal sheath acceleration regime. Particle-In-Cell simulations, performed in the same conditions as the experiment and consistent with the measurements, allow laying a path for further improvement of this acceleration scheme.

  5. The Application of Intensive Longitudinal Methods to Investigate Change: Stimulating the Field of Applied Family Research

    PubMed Central

    Bamberger, Katharine T.

    2015-01-01

    The use of intensive longitudinal methods (ILM)—rapid in situ assessment at micro timescales—can be overlaid on RCTs and other study designs in applied family research. Especially when done as part of a multiple timescale design—in bursts over macro timescales, ILM can advance the study of the mechanisms and effects of family interventions and processes of family change. ILM confers measurement benefits in accurately assessing momentary and variable experiences and captures fine-grained dynamic pictures of time-ordered processes. Thus, ILM allows opportunities to investigate new research questions about intervention effects on within-subject (i.e., within-person, within-family) variability (i.e., dynamic constructs) and about the time-ordered change process that interventions induce in families and family members beginning with the first intervention session. This paper discusses the need and rationale for applying ILM to intervention evaluation, new research questions that can be addressed with ILM, example research using ILM in the related fields of basic family research and the evaluation of individual-based (rather than family-based) interventions. Finally, the paper touches on practical challenges and considerations associated with ILM and points readers to resources for the application of ILM. PMID:26541560

  6. How Health Behaviors Relate to Academic Performance via Affect: An Intensive Longitudinal Study

    PubMed Central

    Flueckiger, Lavinia; Lieb, Roselind; Meyer, Andrea H.; Mata, Jutta

    2014-01-01

    Objective This intensive longitudinal study examined how sleep and physical activity relate to university students’ affect and academic performance during a stressful examination period. Methods On 32 consecutive days, 72 first-year students answered online questionnaires on their sleep quality, physical activity, positive and negative affect, learning goal achievement, and examination grades. First-year university students are particularly well-suited to test our hypotheses: They represent a relatively homogeneous population in a natural, but controlled setting, and simultaneously deal with similar stressors, such as examinations. Data were analyzed using multilevel structural equation models. Results Over the examination period, better average sleep quality but not physical activity predicted better learning goal achievement. Better learning goal achievement was associated with increased probability of passing all examinations. Relations of average sleep quality and average physical activity with learning goal achievement were mediated by experienced positive affect. In terms of day-to-day dynamics, on days with better sleep quality, participants reported better learning goal achievement. Day-to-day physical activity was not related to daily learning goal achievement. Daily positive and negative affect both mediated the effect of day-to-day sleep quality and physical activity on daily learning goal achievement. Conclusion Health behaviors such as sleep quality and physical activity seem important for both academic performance and affect experience, an indicator of mental health, during a stressful examination period. These results are a first step toward a better understanding of between- and within-person variations in health behaviors, affect, and academic performance, and could inform prevention and intervention programs for university students. PMID:25353638

  7. How health behaviors relate to academic performance via affect: an intensive longitudinal study.

    PubMed

    Flueckiger, Lavinia; Lieb, Roselind; Meyer, Andrea H; Mata, Jutta

    2014-01-01

    This intensive longitudinal study examined how sleep and physical activity relate to university students' affect and academic performance during a stressful examination period. On 32 consecutive days, 72 first-year students answered online questionnaires on their sleep quality, physical activity, positive and negative affect, learning goal achievement, and examination grades. First-year university students are particularly well-suited to test our hypotheses: They represent a relatively homogeneous population in a natural, but controlled setting, and simultaneously deal with similar stressors, such as examinations. Data were analyzed using multilevel structural equation models. Over the examination period, better average sleep quality but not physical activity predicted better learning goal achievement. Better learning goal achievement was associated with increased probability of passing all examinations. Relations of average sleep quality and average physical activity with learning goal achievement were mediated by experienced positive affect. In terms of day-to-day dynamics, on days with better sleep quality, participants reported better learning goal achievement. Day-to-day physical activity was not related to daily learning goal achievement. Daily positive and negative affect both mediated the effect of day-to-day sleep quality and physical activity on daily learning goal achievement. Health behaviors such as sleep quality and physical activity seem important for both academic performance and affect experience, an indicator of mental health, during a stressful examination period. These results are a first step toward a better understanding of between- and within-person variations in health behaviors, affect, and academic performance, and could inform prevention and intervention programs for university students.

  8. Multilevel Models for Intensive Longitudinal Data with Heterogeneous Autoregressive Errors: The Effect of Misspecification and Correction with Cholesky Transformation

    PubMed Central

    Jahng, Seungmin; Wood, Phillip K.

    2017-01-01

    Intensive longitudinal studies, such as ecological momentary assessment studies using electronic diaries, are gaining popularity across many areas of psychology. Multilevel models (MLMs) are most widely used analytical tools for intensive longitudinal data (ILD). Although ILD often have individually distinct patterns of serial correlation of measures over time, inferences of the fixed effects, and random components in MLMs are made under the assumption that all variance and autocovariance components are homogenous across individuals. In the present study, we introduced a multilevel model with Cholesky transformation to model ILD with individually heterogeneous covariance structure. In addition, the performance of the transformation method and the effects of misspecification of heterogeneous covariance structure were investigated through a Monte Carlo simulation. We found that, if individually heterogeneous covariances are incorrectly assumed as homogenous independent or homogenous autoregressive, MLMs produce highly biased estimates of the variance of random intercepts and the standard errors of the fixed intercept and the fixed effect of a level 2 covariate when the average autocorrelation is high. For intensive longitudinal data with individual specific residual covariance, the suggested transformation method showed lower bias in those estimates than the misspecified models when the number of repeated observations within individuals is 50 or more. PMID:28286490

  9. LONGITUDINAL AND RADIAL DEPENDENCE OF SOLAR ENERGETIC PARTICLE PEAK INTENSITIES: STEREO, ACE, SOHO, GOES, AND MESSENGER OBSERVATIONS

    SciTech Connect

    Lario, D.; Ho, G. C.; Decker, R. B.; Roelof, E. C.; Aran, A.; Gomez-Herrero, R.; Dresing, N.; Heber, B.

    2013-04-10

    Simultaneous measurements of solar energetic particle (SEP) events by two or more of the spacecraft located near 1 AU during the rising phase of solar cycle 24 (i.e., STEREO-A, STEREO-B, and near-Earth spacecraft such as ACE, SOHO, and GOES) are used to determine the longitudinal dependence of 71-112 keV electron, 0.7-3 MeV electron, 15-40 MeV proton, and 25-53 MeV proton peak intensities measured in the prompt component of SEP events. Distributions of the peak intensities for the selected 35 events with identifiable solar origin are approximated by the form exp [ - ({phi} - {phi}{sub 0}){sup 2}/2{sigma}{sup 2}], where {phi} is the longitudinal separation between the parent active region and the footpoint of the nominal interplanetary magnetic field (IMF) line connecting each spacecraft with the Sun, {phi}{sub 0} is the distribution centroid, and {sigma} determines the longitudinal gradient. The MESSENGER spacecraft, at helioradii R < 1 AU, allows us to determine a lower limit to the radial dependence of the 71-112 keV electron peak intensities measured along IMF lines. We find five events for which the nominal magnetic footpoint of MESSENGER was less than 20 Degree-Sign apart from the nominal footpoint of a spacecraft near 1 AU. Although the expected theoretical radial dependence for the peak intensity of the events observed along the same field line can be approximated by a functional form R {sup -{alpha}} with {alpha} < 3, we find two events for which {alpha} > 3. These two cases correspond to SEP events occurring in a complex interplanetary medium that favored the enhancement of peak intensities near Mercury but hindered the SEP transport to 1 AU.

  10. Syrtis in Retreat

    NASA Technical Reports Server (NTRS)

    2003-01-01

    [figure removed for brevity, see original site]

    Released 30 June 2003

    Lava flows from the broad shield volcano Syrtis Major have poured into the Isidis Basin to the east. The transition between these great provinces is marked by broken slabs of accumulated volcanic material that is retreating from its position on the floor of the basin. A jagged scarp a half a kilometer high is the result.

    Image information: VIS instrument. Latitude 13.7, Longitude 79.4 East (280.6 West). 19 meter/pixel resolution.

    Note: this THEMIS visual image has not been radiometrically nor geometrically calibrated for this preliminary release. An empirical correction has been performed to remove instrumental effects. A linear shift has been applied in the cross-track and down-track direction to approximate spacecraft and planetary motion. Fully calibrated and geometrically projected images will be released through the Planetary Data System in accordance with Project policies at a later time.

    NASA's Jet Propulsion Laboratory manages the 2001 Mars Odyssey mission for NASA's Office of Space Science, Washington, D.C. The Thermal Emission Imaging System (THEMIS) was developed by Arizona State University, Tempe, in collaboration with Raytheon Santa Barbara Remote Sensing. The THEMIS investigation is led by Dr. Philip Christensen at Arizona State University. Lockheed Martin Astronautics, Denver, is the prime contractor for the Odyssey project, and developed and built the orbiter. Mission operations are conducted jointly from Lockheed Martin and from JPL, a division of the California Institute of Technology in Pasadena.

  11. Tips for a Successful Leadership Retreat

    ERIC Educational Resources Information Center

    Bonstingl, John Jay

    2005-01-01

    This article focuses on planning a retreat for board, leadership team, or community and business partners. The author provides 10 suggestions for effective retreat planning: (1) Plan one's retreat with a clear purpose in mind; (2) Make retreat more relevant; (3) Build on current and past successes; (4) Make sure the right people are invited and…

  12. Efficacy of protaper instruments during endodontic retreatment.

    PubMed

    Fariniuk, Luiz Fernando; Azevedo, Marco Antonio Diniz; Carneiro, Everdan; Westphalen, Vânia Portela Ditzel; Piasecki, Lucila; da Silva Neto, Ulisses Xavier

    2017-01-01

    The effectiveness of ProTaper Universal and ProTaper Retreatment rotary instruments was compared to the Hedström files in the removal of filling material from root canals. Thirty-six extracted human mandibular premolars with a single straight root canal were shaped and filled with gutta-percha and AH Plus. The specimens were stored for 6 months at 37°C and at 100% relative humidity, and then randomly divided into three groups: PTU - removal of filling material performed with ProTaper Universal instruments; PTR - removal of filling material performed with ProTaper Retreatment instruments; HF - removal of filling material performed with Gates-Glidden burs, Hedström files and solvent. After the filling material removal and diaphanization, the specimens were longitudinally sectioned and images of the canal surfaces were scanned. The remaining areas of filling material were measured (Image Tool 3.0), and data was analyzed statistically (Kruskal-Wallis and Dunn tests). The time required for filling removal in each group was also recorded (one-way ANOVA and Tukey's HSD test). All groups presented remnants of filling material; PTU had the smallest amount and HF group presented the highest mean value (P< 0.05) in all the thirds. The cervical third had the smallest amount of material when compared with the other thirds (P< 0.05). HF group required a longer mean time, presenting significant difference (P< 0.05). Considering the time required and the amount of the filling removal, ProTaper Retreatment were not superior to ProTaper Universal, but both rotary instruments were more effective and less time-consuming than Hedström manual files.

  13. Fracture Resistance of Retreated Roots Using Different Retreatment Systems

    PubMed Central

    Er, Kursat; Tasdemir, Tamer; Siso, Seyda Herguner; Celik, Davut; Cora, Sabri

    2011-01-01

    Objectives: This study was designed to evaluate the fracture resistance of retreated roots using different rotary retreatment systems. Methods: Forty eight freshly extracted human canine teeth with single straight root canals were instrumented sequentially increasing from size 30 to a size 55 using K-files whit a stepback technique. The teeth were randomly divided into three experimental and one control groups of 12 specimens each. The root canals were filled using cold lateral compaction of gutta-percha and AH Plus (Dentsply Detrey, Konstanz, Germany) sealer in experimental groups. Removal of gutta-percha was performed with the following devices and techniques: ProTaper Universal (Dentsply Maillefer, Ballaigues, Switzerland), R-Endo (Micro-Mega, Besançon, France), and Mtwo (Sweden & Martina, Padova, Italy) rotary retreatment systems. Control group specimens were only instrumented, not filled or retreated. The specimens were then mounted in copper rings, were filled with a self-curing polymethylmethacrylate resin, and the force required to cause vertical root fracture was measured using a universal testing device. The force of fracture of the roots was recorded and the results in the various groups were compared. Statistical analysis was accomplished by one-way ANOVA and a post hoc Tukey tests. Results: There were statistically significant differences between the control and experimental groups (P<.05). However, there were no significant differences among the experimental groups. Conclusions: Based on the results, all rotary retreatment techniques used in this in vitro study produced similar root weakness. PMID:21912497

  14. A Randomized Trial of Longitudinal Effects of Low-Intensity Responsivity Education/Prelinguistic Milieu Teaching

    ERIC Educational Resources Information Center

    Warren, Steven F.; Fey, Marc E.; Finestack, Lizbeth, H.; Brady, Nancy C.; Bredin-Oja, Shelley L.; Fleming, Kandace K.

    2008-01-01

    Purpose: To evaluate the longitudinal effects of a 6-month course of responsivity education (RE)/prelinguistic milieu teaching (PMT) for young children with developmental delay. Method: Fifty-one children, age 24-33 months, with fewer than 10 expressive words were randomly assigned to early-treatment/no-treatment groups. All treatment was added as…

  15. A Longitudinal Examination of Breadth and Intensity of Youth Activity Involvement and Successful Development

    ERIC Educational Resources Information Center

    Busseri, Michael A.; Rose-Krasnor, Linda; Willoughby, Teena; Chalmers, Heather

    2006-01-01

    Connections between youth activity involvement and indicators of successful development were examined in a longitudinal high school sample. Drawing on theories of expertise skill development (e.g., J. Cote, 1999); the selection, optimization, and compensation framework (P. B. Baltes, 1997); and theories of positive youth development (e.g., R. M.…

  16. Intensity of Participation in Organized Youth Activities during the High School Years: Longitudinal Associations with Adjustment

    ERIC Educational Resources Information Center

    Denault, Anne-Sophie; Poulin, Francois; Pedersen, Sara

    2009-01-01

    The goal of this study was to explore the longitudinal associations between youth activity participation and adjustment over the high school years by examining (a) correlations between participation and adjustment growth curves, and (b) bidirectional links between participation and adjustment from one year to the next. Participation was…

  17. USEPA PATHOGEN EQUIVALENCY COMMITTEE RETREAT

    EPA Science Inventory

    The Pathogen Equivalency Committee held its retreat from September 20-21, 2005 at Hueston Woods State Park in College Corner, Ohio. This presentation will update the PEC’s membership on emerging pathogens, analytical methods, disinfection techniques, risk analysis, preparat...

  18. USEPA PATHOGEN EQUIVALENCY COMMITTEE RETREAT

    EPA Science Inventory

    The Pathogen Equivalency Committee held its retreat from September 20-21, 2005 at Hueston Woods State Park in College Corner, Ohio. This presentation will update the PEC’s membership on emerging pathogens, analytical methods, disinfection techniques, risk analysis, preparat...

  19. Gutta-percha retreatment: effectiveness of nickel-titanium rotary instruments versus stainless steel hand files.

    PubMed

    Barrieshi-Nusair, Kefah M

    2002-06-01

    This study compared the cleanliness of the root canal walls after retreatment using nickel titanium (NiTi) rotary and stainless steel (SS) files. Also compared were time of retreatment and canal deviation. Forty extracted canines were step-back prepared and obturated with gutta-percha and sealer. Retreatment was performed either by using chloroform and SS hand files or chloroform and NiTi rotary files. Time for retreatment was recorded. Radiographs of the root canal system before and after retreatment were made. Teeth were split longitudinally, photographed, and projected onto a screen. The amount of gutta-percha/sealer remaining on the canal walls was then traced and measured. The amount remaining was analyzed and compared statistically between NiTi and SS groups by t test. Results showed that the mean percentage of wall coverage by remaining obturating material in the SS group was 13.6% and was 15.2% for the NiTi group. There was no statistically significant difference (p = 0.361). No severe canal deviation occurred with either retreatment method. Mean retreatment time for the SS group was 6.3 min and 7.9 min for the NiTi group; the difference was statistically significant (t test p < 0.001). In conclusion, NiTi rotary and SS hand were similar in material remaining after retreatment, but SS hand was a bit faster.

  20. A Longitudinal Study of Breadth and Intensity of Activity Involvement and the Transition to University

    ERIC Educational Resources Information Center

    Busseri, Michael A.; Rose-Krasnor, Linda; Pancer, S. Mark; Pratt, Michael W.; Adams, Gerald R.; Birnie-Lefcovitch, Shelly; Polivy, Janet; Wintre, Maxine Gallander

    2011-01-01

    We examined prospective relations between activity involvement and successful transitioning to university. A sample of 656 students from 6 Canadian universities completed questionnaires before beginning university and at the end of their first year. Breadth (number of different activity domains) and intensity (mean frequency) of activity…

  1. Twelfth-Grade Student Work Intensity Linked to Later Educational Attainment and Substance Use: New Longitudinal Evidence

    PubMed Central

    Bachman, Jerald G.; Staff, Jeremy; O’Malley, Patrick M.; Schulenberg, John E.; Freedman-Doan, Peter

    2011-01-01

    Long hours of paid employment during high school have been linked to a variety of problem behaviors, but questions remain about whether and to what extent work intensity makes any causal contribution. This study addresses those questions by focusing on how 12th-grade work intensity is associated with substance use and educational attainment in the years following high school. It uses two nationally representative longitudinal data sets from the Monitoring the Future project, spanning a total of three decades. One data set tracks 8th graders for 8 years (modal ages 14–22) and provides extensive controls for possible prior causes; the second larger data set tracks 12th graders for up to 12 years (to modal ages 29–30) and permits assessment of possible short- and longer-term consequences. Findings based on propensity score matching and multivariate regression analyses are highly consistent across the two sets of data. All findings show that more fundamental prior problems, including low academic performance and aspirations, make substantial contributions to substance use and long-term academic attainment (selection effects), but the findings also suggest that high work intensity during high school has long-term costs in terms of college completion and perhaps cigarette use. PMID:21171751

  2. Spatially intensive sampling by electrofishing for assessing longitudinal discontinuities in fish distribution in a headwater stream

    USGS Publications Warehouse

    Le Pichon, Céline; Tales, Évelyne; Belliard, Jérôme; Torgersen, Christian E.

    2017-01-01

    Spatially intensive sampling by electrofishing is proposed as a method for quantifying spatial variation in fish assemblages at multiple scales along extensive stream sections in headwater catchments. We used this method to sample fish species at 10-m2 points spaced every 20 m throughout 5 km of a headwater stream in France. The spatially intensive sampling design provided information at a spatial resolution and extent that enabled exploration of spatial heterogeneity in fish assemblage structure and aquatic habitat at multiple scales with empirical variograms and wavelet analysis. These analyses were effective for detecting scales of periodicity, trends, and discontinuities in the distribution of species in relation to tributary junctions and obstacles to fish movement. This approach to sampling riverine fishes may be useful in fisheries research and management for evaluating stream fish responses to natural and altered habitats and for identifying sites for potential restoration.

  3. Influence of supplemental vitamin D on intensity of benign paroxysmal positional vertigo: A longitudinal clinical study

    PubMed Central

    Sheikhzadeh, Mahboobeh; Lotfi, Yones; Mousavi, Abdollah; Heidari, Behzad; Monadi, Mohsen; Bakhshi, Enayatollah

    2016-01-01

    Background: Benign paroxysmal positional vertigo (BPPV) is linked to vitamin D deficiency. This clinical trial aimed to determine the influence of vitamin D supplementation on intensity of BPPV. Methods: The study population was selected consecutively and the diagnosis of BPPV was made by history and clinical examination and exclusion of other conditions. Intensity of BPVV was assessed based on VAS score (0-10). Serum 25-hydroxyvitamin D (25-OHD) was measured using ELISA method and levels < 20 ng/ml was considered a deficiency. All patients received rehabilitation treatment using Epley's maneuver one time per week for one month. Serum 25-OHD deficient patients were classified as treated and non-treated groups (rehabilitation with or without 50.000 IU cholecalciferol weekly for two months).The results of treatment were compared with vitamin D sufficient group as control. All patients were followed-up for 6 months. Results: After two months of treatment, in both vitamin D treated and non-treated groups the intensity of BPPV decreased significantly as compared with control (P=0.001 for both groups) but at endpoint, the intensity of BPPV aggravated and regressed to the baseline value in vitamin D deficient non-treated group (P=0.001) whereas, in vitamin D treated group, improvement of BPPV remained stable and unchanged over the study period. Conclusion: This study indicates that correction of vitamin D deficiency in BPPV provides additional benefit to rehabilitation therapy (Epley maneuver) regarding duration of improvement. These findings suggest serum 25-OHD measurement in recurrent BPPV. PMID:27386060

  4. A Distributed Network for Intensive Longitudinal Monitoring in Metastatic Triple-Negative Breast Cancer.

    PubMed

    Blau, C Anthony; Ramirez, Arturo B; Blau, Sibel; Pritchard, Colin C; Dorschner, Michael O; Schmechel, Stephen C; Martins, Timothy J; Mahen, Elisabeth M; Burton, Kimberly A; Komashko, Vitalina M; Radenbaugh, Amie J; Dougherty, Katy; Thomas, Anju; Miller, Christopher P; Annis, James; Fromm, Jonathan R; Song, Chaozhong; Chang, Elizabeth; Howard, Kellie; Austin, Sharon; Schmidt, Rodney A; Linenberger, Michael L; Becker, Pamela S; Senecal, Francis M; Mecham, Brigham H; Lee, Su-In; Madan, Anup; Ronen, Roy; Dutkowski, Janusz; Heimfeld, Shelly; Wood, Brent L; Stilwell, Jackie L; Kaldjian, Eric P; Haussler, David; Zhu, Jingchun

    2016-01-01

    Accelerating cancer research is expected to require new types of clinical trials. This report describes the Intensive Trial of OMics in Cancer (ITOMIC) and a participant with triple-negative breast cancer metastatic to bone, who had markedly elevated circulating tumor cells (CTCs) that were monitored 48 times over 9 months. A total of 32 researchers from 14 institutions were engaged in the patient's evaluation; 20 researchers had no prior involvement in patient care and 18 were recruited specifically for this patient. Whole-exome sequencing of 3 bone marrow samples demonstrated a novel ROS1 variant that was estimated to be present in most or all tumor cells. After an initial response to cisplatin, a hypothesis of crizotinib sensitivity was disproven. Leukapheresis followed by partial CTC enrichment allowed for the development of a differential high-throughput drug screen and demonstrated sensitivity to investigational BH3-mimetic inhibitors of BCL-2 that could not be tested in the patient because requests to the pharmaceutical sponsors were denied. The number and size of CTC clusters correlated with clinical status and eventually death. Focusing the expertise of a distributed network of investigators on an intensively monitored patient with cancer can generate high-resolution views of the natural history of cancer and suggest new opportunities for therapy. Optimization requires access to investigational drugs. Copyright © 2016 by the National Comprehensive Cancer Network.

  5. An Intensive Longitudinal Cohort Study of Malian Children and Adults Reveals No Evidence of Acquired Immunity to Plasmodium falciparum Infection

    PubMed Central

    Tran, Tuan M.; Li, Shanping; Doumbo, Safiatou; Doumtabe, Didier; Huang, Chiung-Yu; Dia, Seydou; Bathily, Aboudramane; Sangala, Jules; Kone, Younoussou; Traore, Abdrahamane; Niangaly, Moussa; Dara, Charles; Kayentao, Kassoum; Ongoiba, Aissata; Doumbo, Ogobara K.; Traore, Boubacar; Crompton, Peter D.

    2013-01-01

    Background In experimental models of human and mouse malaria, sterilizing liver stage immunity that blocks progression of Plasmodium infection to the symptomatic blood stage can be readily demonstrated. However, it remains unclear whether individuals in malaria-endemic areas acquire such immunity. Methods In Mali, 251 healthy children and adults aged 4–25 years who were free of blood-stage Plasmodium infection by polymerase chain reaction (PCR) were enrolled in a longitudinal study just prior to an intense 6-month malaria season. Subsequent clinical malaria episodes were detected by weekly active surveillance and self-referral. Asymptomatic P. falciparum infections were detected by blood-smear microscopy and PCR analysis of dried blood spots that had been collected every 2 weeks for 7 months. Results As expected, the risk of clinical malaria decreased with increasing age (log-rank test, P = .0038). However, analysis of PCR data showed no age-related differences in P. falciparum infection risk (log-rank test, P = .37). Conclusions Despite years of exposure to intense P. falciparum transmission, there is no evidence of acquired, sterile immunity to P. falciparum infection in this population, even as clinical immunity to blood-stage malaria is clearly acquired. Understanding why repeated P. falciparum infections do not induce sterile protection may lead to insights for developing vaccines that target the liver stage in malaria-endemic populations. PMID:23487390

  6. Tunable High-Intensity Electron Bunch Train Production Based on Nonlinear Longitudinal Space Charge Oscillation

    NASA Astrophysics Data System (ADS)

    Zhang, Zhen; Yan, Lixin; Du, Yingchao; Zhou, Zheng; Su, Xiaolu; Zheng, Lianmin; Wang, Dong; Tian, Qili; Wang, Wei; Shi, Jiaru; Chen, Huaibi; Huang, Wenhui; Gai, Wei; Tang, Chuanxiang

    2016-05-01

    High-intensity trains of electron bunches with tunable picosecond spacing are produced and measured experimentally with the goal of generating terahertz (THz) radiation. By imposing an initial density modulation on a relativistic electron beam and controlling the charge density over the beam propagation, density spikes of several-hundred-ampere peak current in the temporal profile, which are several times higher than the initial amplitudes, have been observed for the first time. We also demonstrate that the periodic spacing of the bunch train can be varied continuously either by tuning launching phase of a radio-frequency gun or by tuning the compression of a downstream magnetic chicane. Narrow-band coherent THz radiation from the bunch train was also measured with μ J -level energies and tunable central frequency of the spectrum in the range of ˜0.5 to 1.6 THz. Our results pave the way towards generating mJ-level narrow-band coherent THz radiation and driving high-gradient wakefield-based acceleration.

  7. Tunable High-Intensity Electron Bunch Train Production Based on Nonlinear Longitudinal Space Charge Oscillation

    SciTech Connect

    Zhang, Zhen; Yan, Lixin; Du, Yingchao; Zhou, Zheng; Su, Xiaolu; Zheng, Lianmin; Wang, Dong; Tian, Qili; Wang, Wei; Shi, Jiaru; Chen, Huaibi; Huang, Wenhui; Gai, Wei; Tang, Chuanxiang

    2016-05-05

    High-intensity trains of electron bunches with tunable picosecond spacing are produced and measured experimentally with the goal of generating terahertz (THz) radiation. By imposing an initial density modulation on a relativistic electron beam and controlling the charge density over the beam propagation, density spikes of several-hundred-ampere peak current in the temporal profile, which are several times higher than the initial amplitudes, have been observed for the first time. We also demonstrate that the periodic spacing of the bunch train can be varied continuously either by tuning launching phase of a radiofrequency gun or by tuning the compression of a downstream magnetic chicane. Narrow-band coherent THz radiation from the bunch train was also measured with μJ-level energies and tunable central frequency of the spectrum in the range of ~0.5 to 1.6 THz. Our results pave the way towards generating mJ-level narrow-band coherent THz radiation and driving high-gradient wakefield-based acceleration.

  8. Tunable High-Intensity Electron Bunch Train Production Based on Nonlinear Longitudinal Space Charge Oscillation.

    PubMed

    Zhang, Zhen; Yan, Lixin; Du, Yingchao; Zhou, Zheng; Su, Xiaolu; Zheng, Lianmin; Wang, Dong; Tian, Qili; Wang, Wei; Shi, Jiaru; Chen, Huaibi; Huang, Wenhui; Gai, Wei; Tang, Chuanxiang

    2016-05-06

    High-intensity trains of electron bunches with tunable picosecond spacing are produced and measured experimentally with the goal of generating terahertz (THz) radiation. By imposing an initial density modulation on a relativistic electron beam and controlling the charge density over the beam propagation, density spikes of several-hundred-ampere peak current in the temporal profile, which are several times higher than the initial amplitudes, have been observed for the first time. We also demonstrate that the periodic spacing of the bunch train can be varied continuously either by tuning launching phase of a radio-frequency gun or by tuning the compression of a downstream magnetic chicane. Narrow-band coherent THz radiation from the bunch train was also measured with μJ-level energies and tunable central frequency of the spectrum in the range of ∼0.5 to 1.6 THz. Our results pave the way towards generating mJ-level narrow-band coherent THz radiation and driving high-gradient wakefield-based acceleration.

  9. A Longitudinal Study of the TEACCH Program in Different Settings: The Potential Benefits of Low Intensity Intervention in Preschool Children with Autism Spectrum Disorder

    ERIC Educational Resources Information Center

    D'Elia, Lidia; Valeri, Giovanni; Sonnino, Fabiana; Fontana, Ilaria; Mammone, Alessia; Vicari, Stefano

    2014-01-01

    We conducted a longitudinal study of 30 preschool children with autism spectrum disorders (ASDs) to evaluate the potential benefits of the Treatment and Education of Autistic and related Communication Handicapped Children (TEACCH). Fifteen children following a low intensity TEACCH program were assessed four times for autism severity, adaptive…

  10. A Longitudinal Study of the TEACCH Program in Different Settings: The Potential Benefits of Low Intensity Intervention in Preschool Children with Autism Spectrum Disorder

    ERIC Educational Resources Information Center

    D'Elia, Lidia; Valeri, Giovanni; Sonnino, Fabiana; Fontana, Ilaria; Mammone, Alessia; Vicari, Stefano

    2014-01-01

    We conducted a longitudinal study of 30 preschool children with autism spectrum disorders (ASDs) to evaluate the potential benefits of the Treatment and Education of Autistic and related Communication Handicapped Children (TEACCH). Fifteen children following a low intensity TEACCH program were assessed four times for autism severity, adaptive…

  11. The resident retreat for future academicians.

    PubMed

    Culton, Donna A; Rubenstein, David S; Diaz, Luis A

    2010-07-01

    The first Resident Retreat for Future Academicians was held in 2001 with the goal of recruiting and encouraging talented residents interested in careers in academia. In this issue of the JID, Hill et al. present findings to suggest that the retreat has indeed fulfilled its goal. It is our hope that the retreat, which is now in its tenth year, will continue to enlist the future leaders of our specialty.

  12. Columbia Glacier in 1986; 800 meters retreat

    USGS Publications Warehouse

    Krimmel, R.M.

    1987-01-01

    Columbia Glacier, in Prince William Sound, Alaska, continued its rapid retreat in 1986, with a retreat of 800 m. Average velocity of the lower portion of the glacier, 10 September 1986 to 26 January 1987, was three km/yr, or about one-half of the velocity during similar periods for the previous three years. This reduced velocity is a new development in the progression of the retreat, and if the calving rate follows the pattern of previous years, will result in continued retreat. (Author 's abstract)

  13. Within-Person Link between Depressed Affect and Moderate-to-Vigorous Physical Activity in Adolescence: An Intensive Longitudinal Approach.

    PubMed

    Langguth, Nadine; Schmid, Johanna; Gawrilow, Caterina; Stadler, Gertraud

    2016-03-01

    During adolescence, young women and men frequently show low physical activity and elevated depressed affect. This study aimed to examine the within-person link between moderate-to-vigorous physical activity (MVPA) and depressed affect in everyday life. Within an intensive longitudinal approach, adolescents (N = 72; 37% young women; M age = 17.36 years; age range: 12-26 years; mid-90% age range: 13-22 years) wore accelerometers to assess their daily MVPA and reported next-morning and same-evening depressed affect in diaries over eight consecutive days. The within-person link between MVPA and depressed affect on the next morning (time-lagged prediction) and the same evening (same-day link) was analyzed with mixed-effects models. More-than-usual MVPA significantly predicted less next-morning depressed affect on weekdays in young women, to the extent that a 60-min increase in MVPA over the person mean significantly predicted 50 per cent lower next-morning depressed affect. This study encourages the development of individually tailored physical activity interventions that could help adolescents enhance their daily amount of unstructured, self-initiated MVPA to reduce depressed affect. This approach may be particularly suitable for young women who have the highest risk for an inactive lifestyle and elevated depressed affect. © 2016 The International Association of Applied Psychology.

  14. Tuberculosis retreatment 'others' in comparison with classical retreatment cases; a retrospective cohort review.

    PubMed

    Nabukenya-Mudiope, Mary G; Kawuma, Herman Joseph; Brouwer, Miranda; Mudiope, Peter; Vassall, Anna

    2015-09-02

    Many of the countries in sub-Saharan Africa are still largely dependent on microscopy as the mainstay for diagnosis of tuberculosis (TB) including patients with previous history of TB treatment. The available guidance in management of TB retreatment cases is focused on bacteriologically confirmed TB retreatment cases leaving out those classified as retreatment 'others'. Retreatment 'others' refer to all TB cases who were previously treated but with unknown outcome of that previous treatment or who have returned to treatment with bacteriologically negative pulmonary or extra-pulmonary TB. This study was conducted in 11 regional referral hospitals (RRHs) serving high burden TB districts in Uganda to determine the profile and treatment success of TB retreatment 'others' in comparison with the classical retreatment cases. A retrospective cohort review of routinely collected National TB and Leprosy Program (NTLP) facility data from 1 January to 31 December 2010. This study uses the term classical retreatment cases to refer to a combined group of bacteriologically confirmed relapse, return after failure and return after loss to follow-up cases as a distinct group from retreatment 'others'. Distribution of categorical characteristics were compared using Chi-squared test for difference between proportions. The log likelihood ratio test was used to assess the independent contribution of type of retreatment, human immunodeficiency virus (HIV) status, age group and sex to the models. Of the 6244 TB cases registered at the study sites, 733 (11.7%) were retreatment cases. Retreatment 'others' constituted 45.5% of retreatment cases. Co-infection with HIV was higher among retreatment 'others' (70.9%) than classical retreatment cases (53.5%). Treatment was successful in 410 (56.2%) retreatment cases. Retreatment 'others' were associated with reduced odds of success (AOR = 0.44, 95% CI 0.22,0.88) compared to classical cases. Lost to follow up was the commonest adverse outcome (38

  15. Spatial Patterns of Structural Brain Changes in Type 2 Diabetic Patients and Their Longitudinal Progression With Intensive Control of Blood Glucose

    PubMed Central

    Battapady, Harsha; Zhang, Tianhao; Lovato, James; Miller, Michael E.; Williamson, Jeff D.; Launer, Lenore J.; Bryan, R. Nick

    2015-01-01

    OBJECTIVE Understanding the effect of diabetes as well as of alternative treatment strategies on cerebral structure is critical for the development of targeted interventions against accelerated neurodegeneration in type 2 diabetes. We investigated whether diabetes characteristics were associated with spatially specific patterns of brain changes and whether those patterns were affected by intensive versus standard glycemic treatment. RESEARCH DESIGN AND METHODS Using baseline MRIs of 488 participants with type 2 diabetes from the Action to Control Cardiovascular Risk in Diabetes-Memory in Diabetes (ACCORD-MIND) study, we applied a new voxel-based analysis methodology to identify spatially specific patterns of gray matter and white matter volume loss related to diabetes duration and HbA1c. The longitudinal analysis used 40-month follow-up data to evaluate differences in progression of volume loss between intensive and standard glycemic treatment arms. RESULTS Participants with longer diabetes duration had significantly lower gray matter volumes, primarily in certain regions in the frontal and temporal lobes. The longitudinal analysis of treatment effects revealed a heterogeneous pattern of decelerated loss of gray matter volume associated with intensive glycemic treatment. Intensive treatment decelerated volume loss, particularly in regions adjacent to those cross-sectionally associated with diabetes duration. No significant relationship between low versus high baseline HbA1c levels and brain changes was found. Finally, regions in which cognitive change was associated with longitudinal volume loss had only small overlap with regions related to diabetes duration and to treatment effects. CONCLUSIONS Applying advanced quantitative image pattern analysis methods on longitudinal MRI data of a large sample of patients with type 2 diabetes, we demonstrate that there are spatially specific patterns of brain changes that vary by diabetes characteristics and that the

  16. Retreatability of two endodontic sealers, EndoSequence BC Sealer and AH Plus: a micro-computed tomographic comparison.

    PubMed

    Oltra, Enrique; Cox, Timothy C; LaCourse, Matthew R; Johnson, James D; Paranjpe, Avina

    2017-02-01

    Recently, bioceramic sealers like EndoSequence BC Sealer (BC Sealer) have been introduced and are being used in endodontic practice. However, this sealer has limited research related to its retreatability. Hence, the aim of this study was to evaluate the retreatability of two sealers, BC Sealer as compared with AH Plus using micro-computed tomographic (micro-CT) analysis. Fifty-six extracted human maxillary incisors were instrumented and randomly divided into 4 groups of 14 teeth: 1A, gutta-percha, AH Plus retreated with chloroform; 1B, gutta-percha, AH Plus retreated without chloroform; 2A, gutta-percha, EndoSequence BC Sealer retreated with chloroform; 2B, gutta-percha, EndoSequence BC Sealer retreated without chloroform. Micro-CT scans were taken before and after obturation and retreatment and analyzed for the volume of residual material. The specimens were longitudinally sectioned and digitized images were taken with the dental operating microscope. Data was analyzed using an ANOVA and a post-hoc Tukey test. Fisher exact tests were performed to analyze the ability to regain patency. There was significantly less residual root canal filling material in the AH Plus groups retreated with chloroform as compared to the others. The BC Sealer samples retreated with chloroform had better results than those retreated without chloroform. Furthermore, patency could be re-established in only 14% of teeth in the BC Sealer without chloroform group. The results of this study demonstrate that the BC Sealer group had significantly more residual filling material than the AH Plus group regardless of whether or not both sealers were retreated with chloroform.

  17. Retreatability of two endodontic sealers, EndoSequence BC Sealer and AH Plus: a micro-computed tomographic comparison

    PubMed Central

    Oltra, Enrique; Cox, Timothy C.; LaCourse, Matthew R.; Johnson, James D.

    2017-01-01

    Objectives Recently, bioceramic sealers like EndoSequence BC Sealer (BC Sealer) have been introduced and are being used in endodontic practice. However, this sealer has limited research related to its retreatability. Hence, the aim of this study was to evaluate the retreatability of two sealers, BC Sealer as compared with AH Plus using micro-computed tomographic (micro-CT) analysis. Materials and Methods Fifty-six extracted human maxillary incisors were instrumented and randomly divided into 4 groups of 14 teeth: 1A, gutta-percha, AH Plus retreated with chloroform; 1B, gutta-percha, AH Plus retreated without chloroform; 2A, gutta-percha, EndoSequence BC Sealer retreated with chloroform; 2B, gutta-percha, EndoSequence BC Sealer retreated without chloroform. Micro-CT scans were taken before and after obturation and retreatment and analyzed for the volume of residual material. The specimens were longitudinally sectioned and digitized images were taken with the dental operating microscope. Data was analyzed using an ANOVA and a post-hoc Tukey test. Fisher exact tests were performed to analyze the ability to regain patency. Results There was significantly less residual root canal filling material in the AH Plus groups retreated with chloroform as compared to the others. The BC Sealer samples retreated with chloroform had better results than those retreated without chloroform. Furthermore, patency could be re-established in only 14% of teeth in the BC Sealer without chloroform group. Conclusion The results of this study demonstrate that the BC Sealer group had significantly more residual filling material than the AH Plus group regardless of whether or not both sealers were retreated with chloroform. PMID:28194360

  18. In vitro evaluation of efficacy of different rotary instrument systems for gutta percha removal during root canal retreatment

    PubMed Central

    Joseph, Mercy; Malhotra, Amit; Rao, Murali; Sharma, Abhimanyu; Talwar, Sangeeta

    2016-01-01

    Background Complete removal of old filling material during root canal retreatment is fundamental for predictable cleaning and shaping of canal anatomy. Most of the retreatment methods tested in earlier studies have shown inability to achieve complete removal of root canal filling. Therefore the aim of this investigation was to assess the efficacy of three different rotary nickel titanium retreatment systems and Hedstrom files in removing filling material from root canals. Material and Methods Sixty extracted mandibular premolars were decoronated to leave 15 mm root. Specimen were hand instrumented and obturated using gutta percha and AH plus root canal sealer. After storage period of two weeks, roots were retreated with three (Protaper retreatment files, Mtwo retreatment files, NRT GPR) rotary retreatment instrument systems and Hedstroem files. Subsequently, samples were sectioned longitudinally and examined under stereomicroscope. Digital images were recorded and evaluated using Digital Image Analysing Software. The retreatment time was recorded for each tooth using a stopwatch. The area of canal and the residual filling material was recorded in mm2 and the percentage of remaining filling material on canal walls was calculated. Data was analysed using ANOVA test. Results Significantly less amount of residual filling material was present in protaper and Mtwo instrumented teeth (p < 0.05) compared to NRT GPR and Hedstrom files group. Protaper instruments also required lesser time during removal of filling material followed by Mtwo instruments, NRT GPR files and Hedstrom files. Conclusions None of the instruments were able to remove the filling material completely from root canal. Protaper universal retreatment system and Mtwo retreatment files were more efficient and faster compared to NRT GPR fles and Hedstrom files. Key words:Gutta-percha removal, nickel titanium, root canal retreatment, rotary instruments. PMID:27703601

  19. Long-term consequences of an intensive care unit stay in older critically ill patients: design of a longitudinal study

    PubMed Central

    2011-01-01

    Background Modern methods in intensive care medicine often enable the survival of older critically ill patients. The short-term outcomes for patients treated in intensive care units (ICUs), such as survival to hospital discharge, are well documented. However, relatively little is known about subsequent long-term outcomes. Pain, anxiety and agitation are important stress factors for many critically ill patients. There are very few studies concerned with pain, anxiety and agitation and the consequences in older critically ill patients. The overall aim of this study is to identify how an ICU stay influences an older person's experiences later in life. More specific, this study has the following objectives: (1) to explore the relationship between pain, anxiety and agitation during ICU stays and experiences of the same symptoms in later life; and (2) to explore the associations between pain, anxiety and agitation experienced during ICU stays and their effect on subsequent health-related quality of life, use of the health care system (readmissions, doctor visits, rehabilitation, medication use), living situation, and survival after discharge and at 6 and 12 months of follow-up. Methods/Design A prospective, longitudinal study will be used for this study. A total of 150 older critically ill patients in the ICU will participate (ICU group). Pain, anxiety, agitation, morbidity, mortality, use of the health care system, and health-related quality of life will be measured at 3 intervals after a baseline assessment. Baseline measurements will be taken 48 hours after ICU admission and one week thereafter. Follow-up measurements will take place 6 months and 12 months after discharge from the ICU. To be able to interpret trends in scores on outcome variables in the ICU group, a comparison group of 150 participants, matched by age and gender, recruited from the Swiss population, will be interviewed at the same intervals as the ICU group. Discussion Little research has focused on

  20. Endodontic retreatment: an online study guide.

    PubMed

    2008-05-01

    The Editorial Board of the Journal of Endodontics has developed a literature-based study guide of topical areas related to endodontics. This study guide is intended to give the reader a focused review of the essential endodontic literature and does not cite all possible articles related to each topic. Although citing all articles would be comprehensive, it would defeat the idea of a study guide. This section will cover retreatment rationale, corrosion of silver points, retreatment techniques, removal of posts, and possible complications during retreatment.

  1. Glacial Retreat in Chilean Patagonia

    NASA Technical Reports Server (NTRS)

    2002-01-01

    The San Quintin Glacier is the largest outflow glacier of the Northern Patagonian Ice Field in southern Chile. Its terminus is a piedmont lobe just short of the Golfo de Penas on the Pacific Ocean and just north of 47oS. Like many glaciers worldwide during the twentieth century, San Quintin appears to be losing mass and possibly retreating. Such a change is evident in these two photographs taken by astronauts only seven years apart. The first was taken by the crew of STS-068 in October1994 and the second by the Increment 4 crew of the International Space Station in February 2002. Even with the reversal of season and different lighting conditions of these two acquisitions, a loss of mass and change of structure, particularly in the lobe, are strikingly evident in these comparative photos. Glaciers are one of the special topics identified as scientific objectives for monitoring with photography from the International Space Station. Astronaut photography is a complimentary source of remote sensing data available for use with other sensor systems being used to monitor and study glaciers (see an ASTER image of the San Quintin Glacier). They also provide strong, visual context information on glacier environments and processes using a familiar medium, the camera. Images STS068-260-73 and ISS004-E-7267 were provided by the Earth Sciences and Image Analysis Laboratory at Johnson Space Center. Additional images taken by astronauts and cosmonauts can be viewed at the NASA-JSC Gateway to Astronaut Photography of Earth.

  2. Cooperative Spatial Retreat for Resilient Drone Networks.

    PubMed

    Kang, Jin-Hyeok; Kwon, Young-Min; Park, Kyung-Joon

    2017-05-03

    Drones are broadening their scope to various applications such as networking, package delivery, agriculture, rescue, and many more. For proper operation of drones, reliable communication should be guaranteed because drones are remotely controlled. When drones experience communication failure due to bad channel condition, interference, or jamming in a certain area, one existing solution is to exploit mobility or so-called spatial retreat to evacuate them from the communication failure area. However, the conventional spatial retreat scheme moves drones in random directions, which results in inefficient movement with significant evacuation time and waste of battery lifetime. In this paper, we propose a novel spatial retreat technique that takes advantage of cooperation between drones for resilient networking, which is called cooperative spatial retreat (CSR). Our performance evaluation shows that the proposed CSR significantly outperforms existing schemes.

  3. Ocean forcing drives glacier retreat sometimes

    NASA Astrophysics Data System (ADS)

    Bassis, J. N.; Ultee, E.; Ma, Y.

    2015-12-01

    Observations show that marine-terminating glaciers respond to climate forcing nonlinearly, with periods of slow or negligible glacier advance punctuated by abrupt, rapid retreat. Once glacier retreat has initiated, glaciers can quickly stabilize with a new terminus position. Alternatively, retreat can be sustained for decades (or longer), as is the case for Columbia Glacier, Alaska where retreat initiated ~1984 and continues to this day. Surprisingly, patterns of glacier retreat show ambiguous or even contradictory correlations with atmospheric temperature and glacier surface mass balance. Despite these puzzles, observations increasingly show that intrusion of warm subsurface ocean water into fjords can lead to glacier erosion rates that can account for a substantial portion of the total mass lost from glaciers. Here we use a simplified flowline model to show that even relatively modest submarine melt rates (~100 m/a) near the terminus of grounded glaciers can trigger large increases in iceberg calving leading to rapid glacier retreat. However, the strength of the coupling between submarine melt and calving is a strong function of the geometry of the glacier (bed topography, ice thickness and glacier width). This can lead to irreversible retreat when the terminus is thick and grounded deeply beneath sea level or result in little change when the glacier is relatively thin, grounded in shallow water or pinned in a narrow fjord. Because of the strong dependence on glacier geometry, small perturbations in submarine melting can trigger glaciers in their most advanced—and geometrically precarious—state to undergo sudden retreat followed by much slower re-advance. Although many details remain speculative, our model hints that some glaciers are more sensitive than others to ocean forcing and that some of the nonlinearities of glacier response to climate change may be attributable to variations in difficult-to-detect subsurface water temperatures that need to be better

  4. Using Intensive Longitudinal Data Collected via Mobile Phone to Detect Imminent Lapse in Smokers Undergoing a Scheduled Quit Attempt

    PubMed Central

    Ma, Ping; Kendzor, Darla E; Frank, Summer G; Wetter, David W; Vidrine, Damon J

    2016-01-01

    Background Mobile phone‒based real-time ecological momentary assessments (EMAs) have been used to record health risk behaviors, and antecedents to those behaviors, as they occur in near real time. Objective The objective of this study was to determine if intensive longitudinal data, collected via mobile phone, could be used to identify imminent risk for smoking lapse among socioeconomically disadvantaged smokers seeking smoking cessation treatment. Methods Participants were recruited into a randomized controlled smoking cessation trial at an urban safety-net hospital tobacco cessation clinic. All participants completed in-person EMAs on mobile phones provided by the study. The presence of six commonly cited lapse risk variables (ie, urge to smoke, stress, recent alcohol consumption, interaction with someone smoking, cessation motivation, and cigarette availability) collected during 2152 prompted or self-initiated postcessation EMAs was examined to determine whether the number of lapse risk factors was greater when lapse was imminent (ie, within 4 hours) than when lapse was not imminent. Various strategies were used to weight variables in efforts to improve the predictive utility of the lapse risk estimator. Results Participants (N=92) were mostly female (52/92, 57%), minority (65/92, 71%), 51.9 (SD 7.4) years old, and smoked 18.0 (SD 8.5) cigarettes per day. EMA data indicated significantly higher urges (P=.01), stress (P=.002), alcohol consumption (P<.001), interaction with someone smoking (P<.001), and lower cessation motivation (P=.03) within 4 hours of the first lapse compared with EMAs collected when lapse was not imminent. Further, the total number of lapse risk factors present within 4 hours of lapse (mean 2.43, SD 1.37) was significantly higher than the number of lapse risk factors present during periods when lapse was not imminent (mean 1.35, SD 1.04), P<.001. Overall, 62% (32/52) of all participants who lapsed completed at least one EMA wherein they

  5. Selective Root Retreatment: A Novel Approach.

    PubMed

    Nudera, William J

    2015-08-01

    Root canal retreatment is traditionally considered an "all or none" treatment approach. It is typically recommended that all restorative and obturation materials be removed from all roots regardless of the presence or absence of periapical pathosis. In contrast, surgical endodontics is not viewed as an "all or none" treatment approach. Traditionally, only the diseased root(s) is addressed via root-end resection and root-end filling. The use of cone-beam computed tomographic imaging allows for a more accurate evaluation of the periapical status of individual roots associated with multirooted teeth. This information has introduced a novel and conservative treatment alternative for previously endodontically treated teeth with multiple roots presenting with post-treatment disease. This new approach is termed selective root retreatment. Advanced imaging allows the clinician to make predictable treatment decisions with respect to the presence or absence of periapical pathosis of individual roots as opposed to making assumptions about the tooth as a whole. Selective root retreatment combines the approach of nonsurgical retreatment with the selectivity of surgical root resection. In this manner, retreatment could be limited to a single root or roots clearly showing periapical pathosis while leaving the root(s) with no visible or perceived pathosis untouched. Copyright © 2015 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  6. Twelfth-Grade Student Work Intensity Linked to Later Educational Attainment and Substance Use: New Longitudinal Evidence

    ERIC Educational Resources Information Center

    Bachman, Jerald G.; Staff, Jeremy; O'Malley, Patrick M.; Schulenberg, John E.; Freedman-Doan, Peter

    2011-01-01

    Long hours of paid employment during high school have been linked to a variety of problem behaviors, but questions remain about whether and to what extent work intensity makes any causal contribution. This study addresses those questions by focusing on how 12th-grade work intensity is associated with substance use and educational attainment in the…

  7. [Root canal retreatment or surgical apicoectomy?].

    PubMed

    van der Meer, W J; Stegenga, B

    2004-11-01

    Failure of root canal therapy is usually due to re-infection of the root canal system. In most of these cases, an endodontic retreatment is indicated. Patients with persisting apical periodontitis frequently are referred to an oral surgeon for apical surgery, although endodontic retreatment would have been possible in a majority of these cases. When endodontic retreatment is not possible or does not resolve the patient's problems, surgical apicoectomy or extraction might be the only possibilities left. Apical surgery is usually performed by an oral sugeon or by a specially trained dentist. In most surgical clinics beveled resection, followed by an preparation and restoration is performed. New developments, such as microscopic sugery, ultrasonic preparation and newly developed restorative materials are described in this article. Since there is a lack of well-designed comparative clinical studies, no definite conclusions can be drawn with regard to the clinical value of these modern techniques.

  8. Summary of the RHIC Retreat 2007

    SciTech Connect

    Pilat,F.; Gardner, C.; Montag, C.; Roser, T.

    2008-08-01

    The RHIC Retreat 2007 took place on July 16-17 2007 at the Foxwoods Resort in CT, about 3 weeks after the end of the RHIC Run-7. The goal of the Retreat is traditionally to plan the upcoming run in the light of the results from the previous one, by providing a snapshot of the present understanding of the machine and a forum for free and frank discussion. A particular attention was paid to the challenge of increasing the time at store, and the related issue of system reliability. An interesting Session covered all new developments aimed to improve the machine performance and luminosity. In Section 2 we summarize the results from Run-7 for RHIC and the injectors and discuss the present objectives of the RHIC program and performance. Sections 3-6 are summaries of the Retreat sessions focused on preparation for deuteron gold and polarized protons, respectively, machine availability and new developments.

  9. Orthograde retreatment and apexification after unsuccessful endodontic treatment, retreatment and apicectomy.

    PubMed

    Sedgley, C M; Wagner, R

    2003-11-01

    To describe a case where a second orthograde retreatment was successful in the management of an infected mandibular right first molar that previously had received both orthograde and retrograde treatments. Periapical surgery is unlikely to be successful unless the root canal system has been adequately debrided and sealed. A case is described where orthograde endodontic treatment, retreatment and apicectomy were unsuccessful in the management of and infected mandibular right first molar. The periapical radiolucency eventually disappeared following a second orthograde retreatment. Teh second retreatment included 12 months of intracanal calcium hydroxide placement to promote apexification, thus allowing subsequent controlled obturation with gutta percha and AH26. At a 5-year review following completion of treatment, the tooth remained asymptomatic and was in normal function. Orthograde retreatment is a treatment option to manage refractory lesions in teeth that have previously received endodontic treatment, retreatment and apicectomy. Orthograde retreatment using long-term intracanal calcium hydroxide can help promote root-end closure of a resected apex.

  10. Learning Communities in Remote Retreat Settings.

    ERIC Educational Resources Information Center

    Bersch, Gretchen T.; Lund, Carole L.

    2002-01-01

    The example of the formation of a learning community in a Yukon Island retreat center demonstrates the influence of context and the importance of community building. Organic learning occurs through the synthesis of the natural environment, the community, and the learning process. (SK)

  11. Roof Shield for Advance and Retreat Mining

    NASA Technical Reports Server (NTRS)

    Lewis, E. V.

    1985-01-01

    Shield sections change their configuration to suit mining mode. Articulation cylinders raise rear shield to advance position, and locking cylinders hold it there. To change to retreat position articulation cylinders lower shield. Locking pins at edge of outermost shield plate latch shield to chock base. Shield accommodates roof heights ranging from 36 to 60 inches (0.9 to 1.52 meters).

  12. A comparative evaluation of efficacy of protaper universal rotary retreatment system for gutta-percha removal with or without a solvent

    PubMed Central

    Kumar, M. Sita Ram; Sajjan, Girija S.; Satish, Kalyan; Varma, K. Madhu

    2012-01-01

    Aim: The aim was to evaluate and compare the efficacy of ProTaper Universal rotary retreatment system with or without solvent and stainless steel hand files for endodontic filling removal from root canals and also to compare retreatment time for each system. Materials and Methods: Thirty extracted mandibular premolars with single straight canals were endodontically treated. Teeth were divided into three major groups, having 10 specimens each. Removal of obturating material in group 1 by stainless steel hand files with RC Solve, group 2 by ProTaper Universal retreatment instruments and group 3 by ProTaper Universal retreatment instruments along with RC solve was done. Retreatment was considered complete for all groups when no filling material was observed on the instruments. The retreatment time was recorded for each tooth. All specimens were grooved longitudinally in a buccolingual direction. The split halves were examined under a stereomicroscope and images were captured and analyzed. The remaining filling debris area ratios were considered for statistical analysis. Results: With ANOVA test, statistical analysis showed that there was statistically no significant difference regarding the amount of filling remnants between the groups (P < 0.05). Differences between the means of groups are statistically significant regarding the retreatment time. Conclusion: Irrespective of the technique used, all the specimens had some remnants on the root canal wall. ProTaper Universal retreatment system files alone proved to be faster than the other experimental groups. PMID:23230353

  13. Failure of apicoectomy surgery and successful endodontic retreatment.

    PubMed

    Marais, J T

    1998-01-01

    The optimal way to address endodontic failures is to retreat the root canal system first and only then to consider apical surgery. Unfortunately, in practice, it is often not done in this way. Patients are subjected to apical surgery, without any attempts at retreatment. A series of cases is presented illustrating failures of apicoectomy and successful endodontic retreatment.

  14. Children's Use of Retreats in Family Child Care Homes

    ERIC Educational Resources Information Center

    Weinberger, Nanci

    2006-01-01

    The use of retreat spaces by 65 children in 9 family child care homes was assessed in this study. Family child care providers used daily diaries to collect information about children's retreat frequency and associated behavior. The findings revealed that nearly half of the children used informal, readily available retreats during the research…

  15. Microorganism penetration in dentinal tubules of instrumented and retreated root canal walls. In vitro SEM study

    PubMed Central

    Al-Sulaiman, Alaa; Al-Rasheed, Fellwa; Alnajjar, Fatimah; Al-Abdulwahab, Bander; Al-Badah, Abdulhakeem

    2014-01-01

    Objectives This in vitro study aimed to investigate the ability of Candida albicans (C. albicans) and Enterococcus faecalis (E. faecalis) to penetrate dentinal tubules of instrumented and retreated root canal surface of split human teeth. Materials and Methods Sixty intact extracted human single-rooted teeth were divided into 4 groups, negative control, positive control without canal instrumentation, instrumented, and retreated. Root canals in the instrumented group were enlarged with endodontic instruments, while root canals in the retreated group were enlarged, filled, and then removed the canal filling materials. The teeth were split longitudinally after canal preparation in 3 groups except the negative control group. The teeth were inoculated with both microorganisms separately and in combination. Teeth specimens were examined by scanning electron microscopy (SEM), and the depth of penetration into the dentinal tubules was assessed using the SMILE view software (JEOL Ltd). Results Penetration of C. albicans and E. faecalis into the dentinal tubules was observed in all 3 groups, although penetration was partially restricted by dentin debris of tubules in the instrumented group and remnants of canal filling materials in the retreated group. In all 3 groups, E. faecalis penetrated deeper into the dentinal tubules by way of cell division than C. albicans which built colonies and penetrated by means of hyphae. Conclusions Microorganisms can easily penetrate dentinal tubules of root canals with different appearance based on the microorganism size and status of dentinal tubules. PMID:25383343

  16. Moraine formation during an advance/retreat cycle at a temperate alpine glacier

    NASA Astrophysics Data System (ADS)

    Brook, M.; Quincey, D.; Winkler, S.

    2012-04-01

    Mountain glaciers are highly sensitive to variations in temperature and precipitation, and so moraine records from such systems are strong indicators of climate change. Due to the prevailing trend of retreat of the majority of mountain glaciers globally over the last few decades, there are limited opportunities to observe moraine formation, especially at temperate alpine glaciers. In the Southern Alps of New Zealand, while glaciers have all experienced a major retreat since the late 19th century, within this loss of ice mass, there has been a distinct variance in individual glacier response. Indeed, while Tasman Glacier, the longest glacier in the Southern Alps has thinned and entered into the current phase of calving retreat in the early 1990s, the steeper, more responsive glaciers to the west of the Main Divide, such as Franz Josef and Fox Glacier have experienced more elaborate advance/retreat phases. We focus on moraine formation at Fox Glacier, a c. 12.5 km long valley glacier terminating at 300 m above sea level. Fox Glacier retreated substantially since the 1930s, before advancing 800 m between the mid-1980s and 1999. A minor retreat then followed until 2005, succeeded by a 300 m re-advance until 2007-8. Continued retreat and down-wasting has since followed. Superimposed on this alternating advance/retreat cycle, have been minor winter re-advances. Sedimentological and morphological information were combined with detailed observations, historical photos and recent time-lapse photography of the terminus. Characteristics of several modes of moraine formation have been observed: (1) the late 20th century advance culminated in a broad <5 m high terminal moraine, formed by an admixture of "bulldozed" proglacial sediments and dumping of supraglacial material; (2) the 21st century short-lived advances were characterized by 1-2 m high (often multi-crested) ridges with a "saw-tooth" plan-form controlled by longitudinal crevasses outcropping at the terminus; (3) time

  17. Modelling the dynamics of palaeo ice-stream retreat in Marguerite Bay, Antarctica

    NASA Astrophysics Data System (ADS)

    Jamieson, S. S.; Vieli, A.; Livingstone, S. J.; Stokes, C. R.; O'Cofaigh, C.; Hillenbrand, C.

    2010-12-01

    The aim is to use numerical models of ice stream behaviour to understand the processes that triggered and controlled the retreat of the Marguerite Bay palaeo ice stream after the Last Glacial Maximum (LGM). This is important because at present a number of marine-based ice streams in Antarctica are rapidly losing mass. Given the consequences of this mass loss for future sea-level rise, it is crucial to improve our understanding and predictive abilities of grounding line retreat of marine-based ice streams. Because contemporary records of grounding line retreat are very short (decades) and may not be representative of behaviour on century or millennial timescales, we focus on the longer-term post-LGM retreat dynamics of the palaeo ice stream as recorded in the marine-geophysical record. Our approach combines numerical modelling with geomorphological mapping in order to understand the processes that triggered and controlled the hypothesized rapid retreat of the Marguerite Bay palaeo ice-stream. Here we describe the numerical model, modelling approach and results of sensitivity testing to understand the behaviour of the Marguerite Bay palaeo ice stream. High-resolution bathymetric data of the Marguerite Bay area has enabled detailed geomorphological mapping and provides a record of grounding line retreat. These mapping data, set into a chronological framework of deglaciation, are used to constrain a 1-dimensional flowline model of the Marguerite palaeo- ice-stream. The numerical model includes basal, lateral and longitudinal stresses and a robust treatment of grounding-line motion through the use of a constantly adjusting spatial grid. We subject the model to a range of external forcing including changes in sea-level, temperature and accumulation in order to reproduce the geomorphological evidence and therefore understand the dynamics of ice stream retreat in this area. We find that slow-downs or re-stabilisations of the grounding line occur in areas of reverse bed

  18. Variation in Timing, Duration, Intensity, and Direction of Adolescent Growth in the Mandible, Maxilla, and Cranial Base: the Fels Longitudinal Study

    PubMed Central

    Nahhas, Ramzi W.; Valiathan, Manish; Sherwood, Richard J.

    2014-01-01

    There is considerable individual variation in the timing, duration, and intensity of growth that occurs in the craniofacial complex during childhood and adolescence. The purpose of this paper is to describe the extent of this variation between traits and between individuals within the Fels Longitudinal Study. Polynomial multilevel models were used to estimate the ages of onset, peak velocity, and cessation of adolescent growth, the time between these ages, the amount of growth between these ages, and peak velocity. This was done at both the group and individual levels for standard cephalometric measurements of the lengths of the mandible, maxilla, and cranial base, the gonial angle, and the saddle angle. Data are from 293 untreated boys and girls age 4 to 24 years in the Fels Longitudinal Study. The timing of the adolescent growth spurt was, in general, not significantly different between the mandible and the maxilla, with each having an earlier age of onset, later age of peak velocity, and later age of cessation of growth compared to the cranial base length. Compared to lengths, angles had in general later ages of onset, peak velocity, and cessation of growth. Accurate characterization of the ontogenetic trajectories of the traits in the craniofacial complex is critical for both clinicians seeking to optimize treatment timing and anatomists interested in examining heterochrony. PMID:24737730

  19. Retreatments after multifocal intraocular lens implantation: an analysis

    PubMed Central

    Gundersen, Kjell Gunnar; Makari, Sarah; Ostenstad, Steffen; Potvin, Rick

    2016-01-01

    Purpose To determine the incidence and etiology of required retreatment after multifocal intraocular lens (IOL) implantation and to evaluate the methods and clinical outcomes of retreatment. Patients and methods A retrospective chart review of 416 eyes of 209 patients from one site that underwent uncomplicated cataract surgery with multifocal IOL implantation. Biometry, the IOL, and refractive data were recorded after the original implantation, with the same data recorded after retreatment. Comments related to vision were obtained both before and after retreatment for retreated patients. Results The multifocal retreatment rate was 10.8% (45/416 eyes). The eyes that required retreatment had significantly higher residual refractive astigmatism compared with those who did not require retreatment (1.21±0.51 D vs 0.51±0.39 D, P<0.01). The retreatment rate for the two most commonly implanted primary IOLs, blended bifocal (10.5%, 16/152) and bilateral trifocal (6.9%, 14/202) IOLs, was not statistically significantly different (P=0.12). In those requiring retreatment, refractive-related complaints were most common. Retreatment with refractive corneal surgery, in 11% of the eyes, and piggyback IOLs, in 89% of the eyes, was similarly successful, improving patient complaints 78% of the time. Conclusion Complaints related to ametropia were the main reasons for retreatment. Residual astigmatism appears to be an important determinant of retreatment rate after multifocal IOL implantation. Retreatment can improve symptoms for a high percentage of patients; a piggyback IOL is a viable retreatment option. PMID:27041983

  20. Where do coastlines stabilize following rapid retreat?

    NASA Astrophysics Data System (ADS)

    Simms, Alexander R.; Rodriguez, Antonio B.

    2014-03-01

    We present a numerical model that shows that the transgressing upper shoreline of wave-dominated estuaries (bayhead deltas), which commonly contain populous urban and industrial centers, stabilizes, and their rate of retreat decreases at tributary junctions. The decreased rate of retreat across a tributary junction is caused by a decrease in the total accommodation, while sediment supply remains conserved. Our model predicts that bayhead deltas from smaller systems will be located closer to tributary confluences than their larger counterparts. An examination of the modern bayhead deltas in Albemarle Sound, U.S. Atlantic Coast, reveals that bayhead deltas from smaller tributaries are located closer to tributary confluences than bayhead deltas associated with larger tributaries, supporting our model prediction. Our results highlight the importance of antecedent topography created during falling sea-levels on shaping the nature of transgression during the ensuing sea-level rise. In particular, tributary junctions act as pinning points during transgression.

  1. Endodontic retreatment strategies used by general dental practitioners.

    PubMed

    Kvist, Thomas; Heden, Gunnar; Reit, Claes

    2004-04-01

    Root-filled teeth with persistant periapical radiolucencies are often classified as endodontic failures. Studies have shown that general dental practitioners (GDP) do not consistantly suggest retreatment of "failures." The "Praxis Concept" (PC) theory hypothesizes that dentists conceive periapical health and disease as different states on a continuum. This study examined endodontic retreatment concepts among 157 GDPs from Värmland, Sweden. In 6 simulated cases the periapical condition, quality of root filling and presence of a root canal-retained post were systematically varied. Five options were offered: no therapy, wait and see, nonsurgical retreatment, surgical retreatment, and extraction. The investigation showed large interindividual variation in retreatment behavior among the GDPs. Only 9 dentists (6%) where found to repeatedly suggest retreatment of endodontic failures. A majority of GDPs (79%) performed in accordance with PC. The data indicate that several retreatment decision rules are used by Swedish GDPs, but PC-derived strategies attract the majority.

  2. Bering Glacier may be in retreat

    NASA Astrophysics Data System (ADS)

    Bush, Susan

    The Bering Glacier, the largest (6000 km2) and longest (200 km) glacier in North America, may be undergoing a stage of irreversible calving retreat, said Bruce Molnia of the U.S. Geological Survey, Reston, Va. The situation there today appears to be a rapid breaking apart of blocks of ice (icebergs). The retreat has resulted in the formation of Vitus Lake (Figure 1), a large freshwater, icemarginal lake, which may evolve into a saltwater bay or fiord system, said Molnia, the spokesperson for a USGS research group that includes Austin Post, Dennis C. Trabant, and James W. Schoonmaker.Unlike most glaciers that lose ice through melting, calving glaciers like Bering end in bodies of water, such as lakes, and lose icebergs from their termini or margins through fracturing or fragmentation. The icebergs, influenced by surface currents and wind, then drift away. During the past 80 years, retreat of the Bering Glacier has resulted in much of its terminus becoming an iceberg calving margin.

  3. Intensive intervention for children and adolescents with autism in a community setting in Italy: a single-group longitudinal study

    PubMed Central

    2010-01-01

    Background Previous studies have shown favourable results with intensive behavioural treatment for children with autism: evidence has emerged that treatment can be successfully implemented in a community setting and in adolescent participants. The aim of this study was to describe the 2-year adaptive functioning outcome of children and adolescents with autism treated intensively within the context of special autism centres, as well as to evaluate family satisfaction with the activity of the centres. Methods Sixty participants with autism (20 females and 40 males, aged between 4 and 18 years) attending the semi-residential rehabilitation centres for autism located in the Abruzzo region (Central Italy) were followed up and their adaptive functioning was evaluated both at baseline and after one and two years using the Vineland Adaptive Behaviour Scales (VABS). Parents' satisfaction with the service was evaluated using the Orbetello Satisfaction Scale for Children and Adolescent Mental Health. Results The increase in VABS scores was significant on several domains in the different gender and age categories. It is worth noting that male children had improved a great deal (roughly, an effect size >0.20) in the domains of communication, daily living and motor skills (effect sizes 0.34, 0.45 and 0.27 respectively) whereas in male adolescents, a notable increase in VABS scores was recorded in the domain of socialization only (effect size 0.23). On the other hand, adaptive behaviour in female children increased in the domains of socialization and motor skills (effect sizes 0.27 and 0.42 respectively) whereas in female adolescents, good results were achieved in the domains of daily living, socialization and motor skills (effect sizes 0.22, 0.26 and 0.20 respectively). The level of satisfaction of users of the service over time was found to be substantial, even when they had recently started the program. Conclusions Our results support the implementation of special autism

  4. Intensive intervention for children and adolescents with autism in a community setting in Italy: a single-group longitudinal study.

    PubMed

    Valenti, Marco; Cerbo, Renato; Masedu, Francesco; De Caris, Marco; Sorge, Germana

    2010-09-01

    Previous studies have shown favourable results with intensive behavioural treatment for children with autism: evidence has emerged that treatment can be successfully implemented in a community setting and in adolescent participants. The aim of this study was to describe the 2-year adaptive functioning outcome of children and adolescents with autism treated intensively within the context of special autism centres, as well as to evaluate family satisfaction with the activity of the centres. Sixty participants with autism (20 females and 40 males, aged between 4 and 18 years) attending the semi-residential rehabilitation centres for autism located in the Abruzzo region (Central Italy) were followed up and their adaptive functioning was evaluated both at baseline and after one and two years using the Vineland Adaptive Behaviour Scales (VABS). Parents' satisfaction with the service was evaluated using the Orbetello Satisfaction Scale for Children and Adolescent Mental Health. The increase in VABS scores was significant on several domains in the different gender and age categories. It is worth noting that male children had improved a great deal (roughly, an effect size >0.20) in the domains of communication, daily living and motor skills (effect sizes 0.34, 0.45 and 0.27 respectively) whereas in male adolescents, a notable increase in VABS scores was recorded in the domain of socialization only (effect size 0.23). On the other hand, adaptive behaviour in female children increased in the domains of socialization and motor skills (effect sizes 0.27 and 0.42 respectively) whereas in female adolescents, good results were achieved in the domains of daily living, socialization and motor skills (effect sizes 0.22, 0.26 and 0.20 respectively).The level of satisfaction of users of the service over time was found to be substantial, even when they had recently started the program. Our results support the implementation of special autism treatment community centres, based on a

  5. A pilot study of a weekend retreat intervention for family survivors of homicide.

    PubMed

    Tuck, Inez; Baliko, Beverly; Schubert, Christine M; Anderson, Lorraine

    2012-10-01

    Homicide causes negative unintended consequences for family survivors. Family survivors face complicated grief and overwhelming loss with minimal support from others. The authors offered a retreat intervention as a way to ameliorate the effects of the homicidal death for family survivors of homicide. An exploratory longitudinal pilot study examined the feasibility and acceptability of the intervention and explored the impact of the TOZI© Healing intervention on participants' distress symptoms. Eight family members participated in the 2-day retreat and completed surveys at five time intervals over 30 months. Descriptive statistics and correlations were used to analyze the data. Although sample sizes were too small to achieve statistical significance, changes on selected holistic health outcomes, supported by overwhelmingly positive focus group responses to the intervention, affirm the need for further study.

  6. Evaluating the effectiveness of ultraviolet-C lamps for reducing keyboard contamination in the intensive care unit: A longitudinal analysis.

    PubMed

    Gostine, Andrew; Gostine, David; Donohue, Cristina; Carlstrom, Luke

    2016-10-01

    Ultraviolet (UV) spectrum light for decontamination of patient care areas is an effective way to reduce transmission of infectious pathogens. Our purpose was to investigate the efficacy of an automated UV-C device to eliminate bioburden on hospital computer keyboards. The study took place at an academic hospital in Chicago, Illinois. Baseline cultures were obtained from keyboards in intensive care units. Automated UV-C lamps were installed over keyboards and mice of those computers. The lamps were tested at varying cycle lengths to determine shortest effective cycles. Delay after use and prior to cycle initiation was varied to minimize cycle interruptions. Finally, 218 postinstallation samples were analyzed. Of 203 baseline samples, 193 (95.1%) were positive for bacteria, with a median of 120 colony forming units (CFU) per keyboard. There were numerous bacteria linked to health care-associated infections (HAIs), including Staphylococcus, Streptococcus, Enterococcus, Pseudomonas, Pasteurella, Klebsiella, Acinetobacter, and Enterobacter. Of the 193 keyboards, 25 (12.3%) had gram-negative species. Of 218 postinstallation samples, 205 (94%) were sterile. Of the 13 that showed bacterial growth, 6 produced a single CFU. Comparison of pre- and post-UV decontamination median CFU values (120 and 0, respectively) revealed a >99% reduction in bacteria. The UV lamp effectively decontaminates keyboards with minimal interruption and low UV exposure. Further studies are required to determine reduction of HAI transmission with use of these devices. Copyright © 2016 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

  7. Summary of the RHIC Retreat 2008

    SciTech Connect

    Pilat,F.; Brennan, M.; Brown, K.; Fischer, W.; Montag, C.

    2008-08-01

    The main goal of the RHIC Retreat is to review last run's performance and prepare for the next. As always though we also discussed the longer term goals and plans for the facility to put the work in perspective and in the right priority. A straw-man plan for the facility was prepared for the DOE that assumes 30 cryoweek and running 2 species per year. The plan outlines RHIC operations for 2008-2012 and integrates well accelerator and detector upgrades to optimize the physics output with high luminosities. The plans includes guidance from the PAC and has been reviewed by DOE.

  8. Psychological Effects of a 1-Month Meditation Retreat on Experienced Meditators: The Role of Non-attachment

    PubMed Central

    Montero-Marin, Jesus; Puebla-Guedea, Marta; Herrera-Mercadal, Paola; Cebolla, Ausias; Soler, Joaquim; Demarzo, Marcelo; Vazquez, Carmelo; Rodríguez-Bornaetxea, Fernando; García-Campayo, Javier

    2016-01-01

    Background: There are few studies devoted to assessing the impact of meditation-intensive retreats on the well-being, positive psychology, and personality of experienced meditators. We aimed to assess whether a 1-month Vipassana retreat: (a) would increase mindfulness and well-being; (b) would increase prosocial personality traits; and (c) whether psychological changes would be mediated and/or moderated by non-attachment. Method: A controlled, non-randomized, pre-post-intervention trial was used. The intervention group was a convenience sample (n = 19) of experienced meditators who participated in a 1-month Vipassana meditation retreat. The control group (n = 19) comprised matched experienced meditators who did not take part in the retreat. During the retreat, the mean duration of daily practice was 8–9 h, the diet was vegetarian and silence was compulsory. The Experiences Questionnaire (EQ), Non-attachment Scale (NAS), Positive and Negative Affect Schedule (PANAS), Satisfaction With Life Scale (SWLS), Temperament Character Inventory Revised (TCI-R-67), Five Facets Mindfulness Questionnaire (FFMQ), Self-Other Four Immeasurables (SOFI) and the MINDSENS Composite Index were administered. ANCOVAs and linear regression models were used to assess pre-post changes and mediation/moderation effects. Results: Compared to controls, retreatants showed increases in non-attachment, observing, MINDSENS, positive-affect, balance-affect, and cooperativeness; and decreases in describing, negative-others, reward-dependence and self-directedness. Non-attachment had a mediating role in decentring, acting aware, non-reactivity, negative-affect, balance-affect and self-directedness; and a moderating role in describing and positive others, with both mediating and moderating effects on satisfaction with life. Conclusions: A 1-month Vipassana meditation retreat seems to yield improvements in mindfulness, well-being, and personality, even in experienced meditators. Non-attachment might

  9. Psychological Effects of a 1-Month Meditation Retreat on Experienced Meditators: The Role of Non-attachment.

    PubMed

    Montero-Marin, Jesus; Puebla-Guedea, Marta; Herrera-Mercadal, Paola; Cebolla, Ausias; Soler, Joaquim; Demarzo, Marcelo; Vazquez, Carmelo; Rodríguez-Bornaetxea, Fernando; García-Campayo, Javier

    2016-01-01

    Background: There are few studies devoted to assessing the impact of meditation-intensive retreats on the well-being, positive psychology, and personality of experienced meditators. We aimed to assess whether a 1-month Vipassana retreat: (a) would increase mindfulness and well-being; (b) would increase prosocial personality traits; and (c) whether psychological changes would be mediated and/or moderated by non-attachment. Method: A controlled, non-randomized, pre-post-intervention trial was used. The intervention group was a convenience sample (n = 19) of experienced meditators who participated in a 1-month Vipassana meditation retreat. The control group (n = 19) comprised matched experienced meditators who did not take part in the retreat. During the retreat, the mean duration of daily practice was 8-9 h, the diet was vegetarian and silence was compulsory. The Experiences Questionnaire (EQ), Non-attachment Scale (NAS), Positive and Negative Affect Schedule (PANAS), Satisfaction With Life Scale (SWLS), Temperament Character Inventory Revised (TCI-R-67), Five Facets Mindfulness Questionnaire (FFMQ), Self-Other Four Immeasurables (SOFI) and the MINDSENS Composite Index were administered. ANCOVAs and linear regression models were used to assess pre-post changes and mediation/moderation effects. Results: Compared to controls, retreatants showed increases in non-attachment, observing, MINDSENS, positive-affect, balance-affect, and cooperativeness; and decreases in describing, negative-others, reward-dependence and self-directedness. Non-attachment had a mediating role in decentring, acting aware, non-reactivity, negative-affect, balance-affect and self-directedness; and a moderating role in describing and positive others, with both mediating and moderating effects on satisfaction with life. Conclusions: A 1-month Vipassana meditation retreat seems to yield improvements in mindfulness, well-being, and personality, even in experienced meditators. Non-attachment might

  10. Postoperative Pain after Endodontic Retreatment Using Rotary or Reciprocating Instruments: A Randomized Clinical Trial.

    PubMed

    Comparin, Daniel; Moreira, Edson Jorge Lima; Souza, Erick M; De-Deus, Gustavo; Arias, Ana; Silva, Emmanuel João Nogueira Leal

    2017-07-01

    The aim of this randomized clinical trial was to evaluate the influence of rotary or reciprocating retreatment techniques on the incidence, intensity, duration of postoperative pain, and medication intake. After power analysis calculations, 65 patients who needed endodontic retreatment were randomly assigned to 1 of 2 groups according to the instrumentation system used: Mtwo (VDW, Munich, Germany) or Reciproc (VDW). Retreatments were performed in a single visit by an endodontic specialist. Participants were asked to rate the incidence and intensity of the postoperative pain on a verbal rating scale 24, 48, and 72 hours after treatment. Patients were also asked to record the number of prescribed analgesic medication tablets (ibuprofen 400 mg) taken. A logistic regression analysis was used to assess both the incidence and duration of pain. Differences in the intensity of pain were analyzed using the ordinal (linear) chi-square test, and the Mann-Whitney U test was used to assess differences in the intake of analgesic medication between groups. No statistically significant difference was found among the 2 groups in relation to postoperative pain or analgesic medication intake at the 3 time points assessed (P > .05). Multivariate analysis showed a significantly higher incidence of pain after 24 hours when preoperative pain was present and a significantly longer duration of pain for men than women independently of the retreatment technique used. The reciprocating system and the continuous rotary system were found to be equivalent regarding the incidence, intensity, duration of postoperative pain, and intake of analgesic medication. Copyright © 2017 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  11. Variation in timing, duration, intensity, and direction of adolescent growth in the mandible, maxilla, and cranial base: the Fels longitudinal study.

    PubMed

    Nahhas, Ramzi W; Valiathan, Manish; Sherwood, Richard J

    2014-07-01

    There is considerable individual variation in the timing, duration, and intensity of growth that occurs in the craniofacial complex during childhood and adolescence. The purpose of this article is to describe the extent of this variation between traits and between individuals within the Fels Longitudinal Study (FLS). Polynomial multilevel models were used to estimate the ages of onset, peak velocity, and cessation of adolescent growth, the time between these ages, the amount of growth between these ages, and peak velocity. This was done at both the group and individual levels for standard cephalometric measurements of the lengths of the mandible, maxilla, and cranial base, the gonial angle, and the saddle angle. Data are from 293 untreated boys and girls age 4-24 years in the FLS. The timing of the adolescent growth spurt was, in general, not significantly different between the mandible and the maxilla, with each having an earlier age of onset, later age of peak velocity, and later age of cessation of growth as compared to the cranial base length. Compared to lengths, angles had in general later ages of onset, peak velocity, and cessation of growth. Accurate characterization of the ontogenetic trajectories of the traits in the craniofacial complex is critical for both clinicians seeking to optimize treatment timing and anatomists interested in examining heterochrony. © 2014 Wiley Periodicals, Inc.

  12. A longitudinal investigation of posttraumatic stress and depressive symptoms over the course of the year following medical-surgical intensive care unit admission.

    PubMed

    Davydow, Dimitry S; Zatzick, Douglas; Hough, Catherine L; Katon, Wayne J

    2013-01-01

    The objective was to identify risk factors for posttraumatic stress disorder (PTSD) and depressive symptoms after medical-surgical intensive care unit (ICU) admission. This longitudinal investigation included 150 medical-surgical ICU patients. We assessed acute stress and post-ICU PTSD symptoms with the PTSD Checklist-Civilian Version and post-ICU depressive symptoms with the Patient Health Questionnaire-9. Mixed-model linear regression ascertained associations between patient and clinical characteristics and repeated measures of post-ICU PTSD and depressive symptoms. The prevalences of substantial PTSD and depressive symptoms were 16% and 31% at 3 months post-ICU and 15% and 17% at 12 months post-ICU, respectively. In-hospital substantial acute stress symptoms [beta: 16.9, 95% confidence Interval (CI): 11.4, 22.4] were independently associated with increased post-ICU PTSD symptoms. Lifetime history of major depression (beta: 2.2, 95% CI: 0.1, 4.2), greater prior trauma exposure (beta: 0.5, 95% CI: 0.2, 0.9) and in-hospital substantial acute stress symptoms (beta: 3.5, 95% CI: 0.8, 6.2) were independently associated with increased post-ICU depressive symptoms. In-hospital acute stress symptoms may represent a modifiable risk factor for psychiatric morbidity in ICU survivors. Early interventions for at-risk ICU survivors may improve longer-term psychiatric outcomes. Copyright © 2013 Elsevier Inc. All rights reserved.

  13. Retreat behavior of a charged droplet for electrohydrodynamic inkjet printing

    NASA Astrophysics Data System (ADS)

    Yudistira, Hadi Teguh; Nguyen, Vu Dat; Tran, Si Bui Quang; Kang, Tae Sam; Park, Jung Keun; Byun, Doyoung

    2011-02-01

    The charged droplet retreat phenomenon in electrohydrodynamic inkjet printing is experimentally observed and theoretically explained. If the charge concentration of a droplet generated from a nozzle is high enough, Coulomb fission is generated a second time and the main droplet retreats to the meniscus on the nozzle. The retreat phenomenon is due to interactions between the charged droplet, the meniscus, and charges on the substrate. The Rayleigh limit is used to give a theoretical estimate of the amount of charge on the droplet and the meniscus during the retreat.

  14. Evaluation of the Success Rate of Nonsurgical Single Visit Retreatment

    PubMed Central

    Ashraf, Hengameh; Milani, Amin Salem; Shakeri Asadi, Shahla

    2007-01-01

    INTRODUCTION: Advantages of endodontic treatments over tooth extraction have increased the demands for these treatments. Success rate of these treatments is generally lower than the primary root canal therapies. Recently, single visit treatments have gained more popularity. But, the influence of completing retreatment in a single appointment on success of the treatment is still a controversy. The aim of this study was evaluating the most common causes of failures and determining the success rate of completing retreatments in single appointment. MATERIALS AND METHODS: Hundred and twenty four patients who had single appointment retreatment within past 4 years in postgraduate ward of Shahid Beheshti Dental School were selected and clinical and radiographic examinations were carried out. The data were analyzed by SPSS using Chi-square and Exact Fisher tests. RESULTS: Success rate and uncertain cases were shown to be 50.7% and 34.2%, respectively and failure rate was 15.1%. Presence of periradicular lesion or history of swelling prior to retreatment had significant effect on the success of single visit retreatments (p<0.001). Another important finding of the study was that the success rate of retreatments was significantly higher in cases referred for restorative purposes compared with retreatments for nonrestorative purposes (p<0.001). CONCLUSION: The overall success rate of single appointment retreatments is up to 84.9% which is considerably higher in cases referred for restorative purposes. So based on the results of this study single appointment retreatment of symptom less teeth is recommended. PMID:24327818

  15. Stream temperature response to glacier retreat (Invited)

    NASA Astrophysics Data System (ADS)

    Moore, R. D.

    2013-12-01

    Stream temperature is a fundamental aspect of aquatic habitat, and there has been increasing concern in recent years that climatic change and glacier retreat will result in increased water temperatures, with potentially negative influences on cold and cool water species such as salmonids. A statistical model was developed to predict the maximum weekly average stream temperature based on data from 418 sites located throughout British Columbia, Canada. Catchment-scale glacier coverage was a significant predictor in the model, and example calculations indicate that plausible decreases in glacier coverage over the next few decades have the potential to result in warming that would be sufficient to cause shifts in fish species assemblages. However, this space-for-time substitution rests on assumptions that may not be valid, especially in the context of a changing climate, leading to a need to develop and apply physically based models. Reach-scale energy budget analyses indicate that parameterizations of energy fluxes used in current stream temperature models are not appropriate for steep channels with cascading flow. In particular, the sensible and latent heat fluxes are more efficient than in lower-gradient channels, and the albedo is enhanced by aeration. Over longer time scales, development of riparian forest has the potential to mitigate the effect of glacier retreat in alpine areas by shading the stream, but it may take centuries for functional riparian forest to develop at higher elevation sites.

  16. GPCR Retreat 2012: timing is everything.

    PubMed

    Chidiac, Peter; Hébert, Terence E

    2013-06-01

    In London, Ontario, the 13th Annual Joint meeting of the Great Lakes GPCR Retreat and the Club des Récepteurs à Sept Domaines Transmembranaires (known simply as the GPCR Retreat) was held on 17-19 October 2012, organized by Steve Ferguson and Peter Chidiac. This meeting gathered together a core group of investigators from Michigan, Ontario and Québec and has steadily increased its attendance in both the eastern (Europe) and western (USA, Canada) directions. This year's buzz naturally centered around the Nobel Prize in Chemistry, which was won the week before by Brian Kobilka and Robert Lefkowitz for their work on receptor structure and function. Michel Bouvier provided a heartfelt tribute to one of the attendees, Marc Caron, a pioneer in the GPCR field, has made many contributions to the work that led to this year's Nobel Prize. The meeting featured interesting sessions on the physiological roles of GPCRs in the nervous system, circadian biology and cancer, dealing at the cellular and molecular level with GPCR, G protein and effector structure and function, regulation and trafficking--with an overall focus on how to move molecular pharmacology in vivo.

  17. Effects of recovery mode (active vs. passive) on performance during a short high-intensity interval training program: a longitudinal study.

    PubMed

    Ben Abderrahman, Abderraouf; Zouhal, Hassane; Chamari, Karim; Thevenet, Delphine; de Mullenheim, Pierre-Yves; Gastinger, Steven; Tabka, Zouhair; Prioux, Jacques

    2013-06-01

    The aim of this longitudinal study was to compare two recovery modes (active vs. passive) during a seven-week high-intensity interval training program (SWHITP) aimed to improve maximal oxygen uptake ([Formula: see text]), maximal aerobic velocity (MAV), time to exhaustion (t lim) and time spent at a high percentage of [Formula: see text], i.e., above 90 % (t90 [Formula: see text]) and 95 % (t95 [Formula: see text]) of [Formula: see text]. Twenty-four adults were randomly assigned to a control group that did not train (CG, n = 6) and two training groups: intermittent exercise (30 s exercise/30 s recovery) with active (IEA, n = 9) or passive recovery (IEP, n = 9). Before and after seven weeks with (IEA and IEP) or without (CG) high-intensity interval training (HIT) program, all subjects performed a maximal graded test to determine their [Formula: see text] and MAV. Subsequently only the subjects of IEA and IEP groups carried out an intermittent exercise test consisting of repeating as long as possible 30 s intensive runs at 105 % of MAV alternating with 30 s active recovery at 50 % of MAV (IEA) or 30 s passive recovery (IEP). Within IEA and IEP, mean t lim and MAV significantly increased between the onset and the end of the SWHITP and no significant difference was found in t90 VO2max and t95 VO2max. Furthermore, before and after the SWHITP, passive recovery allowed a longer t lim for a similar time spent at a high percentage of VO2max. Finally, within IEA, but not in IEP, mean VO2max increased significantly between the onset and the end of the SWHITP both in absolute (p < 0.01) and relative values (p < 0.05). In conclusion, our results showed a significant increase in VO2max after a SWHITP with active recovery in spite of the fact that t lim was significantly longer (more than twice longer) with respect to passive recovery.

  18. Comparative SEM evaluation of three solvents used in endodontic retreatment: an ex vivo study.

    PubMed

    Scelza, Miriam F Zaccaro; Coil, Jeffrey M; Maciel, Ana Carolina de Carvalho; Oliveira, Lílian Rachel L; Scelza, Pantaleo

    2008-01-01

    This study compared, by scanning electron microscopy (SEM), the efficacy of three solvents on the removal of filling materials from dentinal tubules during endodontic retreatment. Forty human maxillary canines with straight canals were prepared according to a crown-down technique and enlarged to a#30 apical file size, before obturation with gutta-percha and a zinc-oxide-eugenol based sealer. The samples were stored for 3 months before being randomly assigned to four groups: chloroform (n=10), orange oil (n=10), eucalyptol (n=10) and control (n=10). Solvents were applied to a reservoir created on the coronal root third using Gates Glidden drills. The total time for retreatment using the solvents was 5 minutes per tooth. Following retreatment the roots were split longitudinally for SEM evaluation. SEM images were digitized, analyzed using Image ProPlus 4.5 software, and the number of dentinal tubules free of filling material from the middle and apical thirds was recorded. No significant difference was found among the solvent groups regarding the number of dentinal tubules free of root filling remnants in the middle and apical root thirds (p>0.05). However, the control group had fewer dentinal tubules free of filling material (p<0.05). Under the tested conditions, it may be concluded that there was no significant difference among the solvents used to obtain dentinal tubules free of filling material remnants.

  19. COMPARATIVE SEM EVALUATION OF THREE SOLVENTS USED IN ENDODONTIC RETREATMENT: AN EX VIVO STUDY

    PubMed Central

    Scelza, Miriam F. Zaccaro; Coil, Jeffrey M.; Maciel, Ana Carolina de Carvalho; Oliveira, Lílian Rachel L.; Scelza, Pantaleo

    2008-01-01

    This study compared, by scanning electron microscopy (SEM), the efficacy of three solvents on the removal of filling materials from dentinal tubules during endodontic retreatment. Forty human maxillary canines with straight canals were prepared according to a crown-down technique and enlarged to a#30 apical file size, before obturation with gutta-percha and a zinc-oxide-eugenol based sealer. The samples were stored for 3 months before being randomly assigned to four groups: chloroform (n=10), orange oil (n=10), eucalyptol (n=10) and control (n=10). Solvents were applied to a reservoir created on the coronal root third using Gates Glidden drills. The total time for retreatment using the solvents was 5 minutes per tooth. Following retreatment the roots were split longitudinally for SEM evaluation. SEM images were digitized, analyzed using Image ProPlus 4.5 software, and the number of dentinal tubules free of filling material from the middle and apical thirds was recorded. No significant difference was found among the solvent groups regarding the number of dentinal tubules free of root filling remnants in the middle and apical root thirds (p>0.05). However, the control group had fewer dentinal tubules free of filling material (p<0.05). Under the tested conditions, it may be concluded that there was no significant difference among the solvents used to obtain dentinal tubules free of filling material remnants. PMID:19089285

  20. Latest Word on Retreat of the West Antarctic Ice Sheet

    NASA Technical Reports Server (NTRS)

    Bindschadler, R.

    2000-01-01

    The West Antarctic ice sheet during the Last Glacial Maximum (LGM) is estimated to have been three times its present volume and to have extended close to the edge of the continental shelf Holocene retreat of this ice sheet in the Ross Sea began between 11,000 and 12,000 years ago. This history implies an average contribution of this ice sheet to sea level of 0.9 mm/a. Evidence of dateable past grounding line positions in the Ross sector are broadly consistent with a linear retreat model. However, inferred rates of retreat for some of these grounding line positions are not consistent with a linear retreat model. More rapid retreat approximately 7600 years ago and possible near-stability in the Ross Sea sector at present suggest a slow rate of initial retreat followed by a more rapid-than-average retreat during the late Holocene, returning to a near-zero rate of retreat currently. This model is also consistent with the mid-Holocene high stand observations of eustatic sea level. Recent compilation of Antarctic bed elevations (BEDMAP) illustrates that the LGM and present grounding lines occur in the shallowest waters, further supporting the model of a middle phase of rapid retreat bracketed by an older and a more recent phase of modest retreat. Extension of these hypotheses into the future make subsequent behavior of the West Antarctic ice sheet more difficult to predict but suggest that if it loses its hold on the present shallow bed, the final retreat of the ice sheet could be very rapid.

  1. Latest Word on Retreat of the West Antarctic Ice Sheet

    NASA Technical Reports Server (NTRS)

    Bindschadler, R.

    2000-01-01

    The West Antarctic ice sheet during the Last Glacial Maximum (LGM) is estimated to have been three times its present volume and to have extended close to the edge of the continental shelf Holocene retreat of this ice sheet in the Ross Sea began between 11,000 and 12,000 years ago. This history implies an average contribution of this ice sheet to sea level of 0.9 mm/a. Evidence of dateable past grounding line positions in the Ross sector are broadly consistent with a linear retreat model. However, inferred rates of retreat for some of these grounding line positions are not consistent with a linear retreat model. More rapid retreat approximately 7600 years ago and possible near-stability in the Ross Sea sector at present suggest a slow rate of initial retreat followed by a more rapid-than-average retreat during the late Holocene, returning to a near-zero rate of retreat currently. This model is also consistent with the mid-Holocene high stand observations of eustatic sea level. Recent compilation of Antarctic bed elevations (BEDMAP) illustrates that the LGM and present grounding lines occur in the shallowest waters, further supporting the model of a middle phase of rapid retreat bracketed by an older and a more recent phase of modest retreat. Extension of these hypotheses into the future make subsequent behavior of the West Antarctic ice sheet more difficult to predict but suggest that if it loses its hold on the present shallow bed, the final retreat of the ice sheet could be very rapid.

  2. Greenland Ice Sheet retreat during the Eemian

    NASA Astrophysics Data System (ADS)

    van de Berg, W. J.; Helsen, M. M.; van de Wal, R. S. W.; van den Broeke, M. R.; Oerlemans, J.

    2012-04-01

    We present a new estimate of the evolution of the Greenland Ice Sheet through the Eemian (130 till 115 ky BP). This estimate is determined using the 3D 'shallow' ice sheet model ANICE and the regional climate model RACMO2/GR. The two models are time-slice coupled with an interval of 1500 years. 3D interpolated surface mass balance fields from RACMO2/GR force ANICE. Eemian and post-Eemian climate from the GCM ECHO-G drives RACMO2/GR on its lateral boundaries. These boundaries are gradually adjusted from maximum Eemian conditions to post-Eemian inception conditions, following the orbital parameters and Greenhouse gas concentrations derived from ice cores. The simulation shows a steady mass loss till the insolation conditions decline and the summer climate cools, with a typical rate of mass loss equivalent to 5 cm sea level rise per century for most of the time. Once summer start to cool the Greenland ice sheet recovers fast. The maximum ice loss is about 2 m eustatic sea level compared to present day volume and originates predominantly from southwest Greenland. Our results align with paleo-observations of Eemian ice sheet existence in South Greenland. Strong summer radiation also induces ice retreat in northern Greenland. Moreover, it agrees with preceding studies that the Greenland ice sheet had only a limited contribution to the Eemian sea level high stand. A finding of this novel approach is the impact of topographic pinpoints on the ice sheet evolution. Subglacial topography, like at 52° W 72° N (near Uummannaq), cause promontories in the ice sheet that enhances snowfall. Locations with high snowfall react less on warming than dry locations, because more melt is needed before all snow is removed, and the more efficient ice melt starts. The reduced ice depth also buttresses inland ice, limiting the ice sheet response to enhanced ablation. As a result, this topographical feature becomes the northern limit of significant ice sheet retreat, and shields the north

  3. Re-Treatment With Ethambutol After Toxic Optic Neuropathy.

    PubMed

    Bouffard, Marc A; Nathavitharana, Ruvandhi R; Yassa, David S; Torun, Nurhan

    2017-03-01

    There are no data in the literature regarding the safety of re-treatment with ethambutol for recurrent mycobacterial infection after prior ethambutol-induced optic neuropathy. We describe a patient who developed optic neuropathy attributed to ethambutol, recovered fully after drug withdrawal, and tolerated a 14-month long re-treatment 10 years later without developing recurrent optic neuropathy.

  4. Academic Writing Retreat: A Time for Rejuvenated and Focused Writing

    ERIC Educational Resources Information Center

    Swaggerty, Elizabeth A.; Atkinson, Terry S.; Faulconer, Johna L.; Griffith, Robin R.

    2011-01-01

    The purpose of this article is to describe the impact of a three-day academic writing retreat on the writing lives of four female university faculty members. Goals of the retreat included rejuvenating their writing lives, focusing their research agendas, improving their writing, and engaging in concentrated blocks of writing and collaborative…

  5. Academic Writing Retreat: A Time for Rejuvenated and Focused Writing

    ERIC Educational Resources Information Center

    Swaggerty, Elizabeth A.; Atkinson, Terry S.; Faulconer, Johna L.; Griffith, Robin R.

    2011-01-01

    The purpose of this article is to describe the impact of a three-day academic writing retreat on the writing lives of four female university faculty members. Goals of the retreat included rejuvenating their writing lives, focusing their research agendas, improving their writing, and engaging in concentrated blocks of writing and collaborative…

  6. Writing Retreat as Structured Intervention: Margin or Mainstream?

    ERIC Educational Resources Information Center

    Murray, Rowena; Newton, Mary

    2009-01-01

    Academics across the world face increasing pressure to publish. Research shows that writing retreats have helped by creating dedicated writing time and building collegiality. A new form of "structured" writing retreat was created to increase its impact by taking a community of practice approach. This paper reports on an evaluation, funded by the…

  7. Epidemiologic evaluation of the outcomes of orthograde endodontic retreatment.

    PubMed

    Salehrabi, Robert; Rotstein, Ilan

    2010-05-01

    Teeth undergoing initial endodontic therapy have a very high survival rate. Some teeth that continue to show signs of pathosis after the initial therapy will require nonsurgical (orthograde) retreatment. Outcome assessment of endodontic retreatment is crucial for appropriate case selection and treatment planning. However, reports on outcomes of orthograde endodontic retreatment performed by endodontists are limited in number, and the reported data vary. In this study, outcomes of orthograde endodontic retreatment performed on 4744 teeth were assessed during a period of 5 years. Data were obtained from retreatments that were performed by endodontists participating in the Delta Dental Insurance plan that insures approximately 15 million individuals in the USA. Overall, 89% of teeth were retained in the oral cavity 5 years after the endodontic retreatment. Four percent of all teeth underwent apical surgery that occurred mostly within 2 years from completion of orthograde retreatment. Eleven percent of teeth were extracted at the end of the 5-year observation period. It appears that orthograde endodontic retreatment yields high incidence of tooth retention after 5 years. Copyright (c) 2010 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  8. Overcoming Obstacles To Create Retreats in Family Child Care.

    ERIC Educational Resources Information Center

    Weinberger, Nanci

    2000-01-01

    Discusses the importance of creating retreat spaces for young children in child care settings. Identifies special challenges and opportunities for creating such spaces in family child care homes. Outlines research findings detailing the benefits of retreats for children, and discusses the contributions of location, form, and materials in creating…

  9. Efficacy of 2 reciprocating systems compared with a rotary retreatment system for gutta-percha removal.

    PubMed

    Rios, Marcos de Azevêdo; Villela, Alexandre Mascarenhas; Cunha, Rodrigo Sanches; Velasco, Rafael Cortez; De Martin, Alexandre Sigrist; Kato, Augusto Shoji; Bueno, Carlos Eduardo da Silveira

    2014-04-01

    The maximum removal of root canal filling material is essential for successful endodontic retreatment. The purpose of this study was to assess the efficacy of 2 reciprocating systems (Reciproc [VDW, Munich, Germany] and WaveOne [Dentsply Maillefer, Ballaigues, Switzerland]) compared with a nickel-titanium (NiTi) rotary system (ProTaper Universal Retreatment [Dentsply Maillefer]) in the removal of root canal filling material. Sixty root canals of extracted human maxillary incisors were prepared using the NiTi ProTaper rotary system with the complementary use of a #40 K-type file and then obturated. The specimens were divided into 3 groups (n = 20) according to the system used for filling removal: group 1: instrument R25 of the Reciproc system, group 2: primary instrument of the WaveOne system, and group 3: NiTi rotary instruments of the ProTaper Universal Retreatment system. The teeth were cleaved longitudinally and photographed under a dental operating microscope with 5 × magnification. Images were transferred to a computer, and residual filling material was quantified using Image Tool software (University of Texas Health Science Center, San Antonio, TX). Results were compared using 1-way analysis of variance (P < .05). All teeth examined had filling remnants within the canal. No statistically significant difference (P > .05) in residual filling material was observed among the groups, with 4.30% in group 1, 2.98% in group 2, and 3.14% in group 3. The Reciproc and WaveOne reciprocating systems were as effective as the ProTaper Universal retreatment system for gutta-percha and sealer removal. Copyright © 2014 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  10. Modelling Waterfall Retreat in Heterogenous Bedrock

    NASA Astrophysics Data System (ADS)

    Attal, M.; Hodge, R. A.; Williams, R.; Baynes, E.

    2016-12-01

    Bedrock rivers are the mediators of environmental change through mountainous landscapes. In response to an increase in uplift rate for example, a "knickpoint" (often materialised as a waterfall) will propagate upstream, separating a domain downstream where the river and its adjacent hillslopes have steepened in response to the change from a "relict" domain upstream which is adjusted to the conditions before the change (Crosby and Whipple 2006). Many studies assume that knickpoint propagation rate scales with drainage area, based on the stream power theory. However, recent studies in a range of locations have found no obvious relationship between knickpoint retreat rate and drainage area, potentially resulting from the stream power law neglecting (i) the influence of sediment on the processes associated with waterfall migration and (ii) thresholds for bedrock detachment (Cook et al. 2013; Mackey et al. 2014; DiBiase et al. 2015; Baynes et al. 2015; Brocard et al. 2016). In this study, we develop a 1D model of waterfall retreat in horizontally bedded bedrock with varying joint spacing. In the model, knickpoint migration is based on two rules: a waterfall will start migrating once the threshold flow depth (a function of knickpoint height and joint spacing) has been exceeded (Lamb and Dietrich 2009), and the migration rate will then be a function of the water-depth-to-waterfall-height ratio, based on experimental results by Baynes (2015). Using a hydrograph based on a Poisson rectangular pulse rainfall simulator (Tucker and Bras 2001), we demonstrate the importance of structure in controlling the speed at which waterfalls migrate but also their number and the length over which they are distributed (Fig. 1). The model is applied to the Jökulsá á Fjöllum, NE Iceland, where rapid migration of waterfalls as a result of discrete events has been identified (Baynes et al. 2015), using new constraints on joint spacing derived from high resolution lidar survey of the gorge

  11. Quality of Life and Survival Outcome for Patients With Nasopharyngeal Carcinoma Receiving Three-Dimensional Conformal Radiotherapy vs. Intensity-Modulated Radiotherapy-A Longitudinal Study

    SciTech Connect

    Fang, F.-M. Chien, C.-Y.; Tsai, W.-L.; Chen, H.-C.; Hsu, H.-C.; Lui, C.-C.; Huang, T.-L.

    2008-10-01

    Purpose: To investigate the changes of quality of life (QoL) and survival outcomes for patients with nasopharyngeal carcinoma (NPC) treated by three-dimensional conformal radiotherapy (3D-CRT) vs. intensity-modulated radiotherapy (IMRT). Methods and Materials: Two hundred and three newly diagnosed NPC patients, who were curatively treated by 3D-CRT (n = 93) or IMRT (n = 110) between March 2002 and July 2004, were analyzed. The distributions of clinical stage according to American Joint Committee on Cancer 1997 were I: 15 (7.4%), II: 78 (38.4%), III: 74 (36.5%), and IV: 36 (17.7%). QoL was longitudinally assessed by the European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30 and the EORTC QLQ-H and N35 questionnaires at the five time points: before RT, during RT (36 Gy), and 3 months, 12 months, and 24 months after RT. Results: The 3-year locoregional control, metastasis-free survival, and overall survival rates were 84.8%, 76.7%, and 81.7% for the 3D-CRT group, respectively, compared with 84.2%, 82.6%, and 85.4% for the IMRT group (p value > 0.05). A general trend of maximal deterioration in most QoL scales was observed during RT, followed by a gradual recovery thereafter. There was no significant difference in most scales between the two groups at each time point. The exception was that patients treated by IMRT had a both statistically and clinically significant improvement in global QoL, fatigue, taste/smell, dry mouth, and feeling ill at the time point of 3 months after RT. Conclusions: The potential advantage of IMRT over 3D-CRT in treating NPC patients might occur in QoL outcome during the recovery phase of acute toxicity.

  12. Association between Participation in an Intensive Longitudinal Assessment Program and Performance on a Cognitive Examination in the Maintenance of Certification in Anesthesiology Program®.

    PubMed

    Sun, Huaping; Zhou, Yan; Culley, Deborah J; Lien, Cynthia A; Harman, Ann E; Warner, David O

    2016-11-01

    As part of the Maintenance of Certification in Anesthesiology Program® (MOCA®), the American Board of Anesthesiology (Raleigh, North Carolina) developed the MOCA Minute program, a web-based intensive longitudinal assessment involving weekly questions with immediate feedback and links to learning resources. This observational study tested the hypothesis that individuals who participate in the MOCA Minute program perform better on the MOCA Cognitive Examination (CE) compared with those who do not participate. Two separate cohorts of individuals eligible for July 2014 and January 2015 CEs were invited to participate in this pilot. The CE scores for each cohort were compared between those who did and did not participate, controlling for the factors known to affect performance. For the first cohort, examination performances for topics covered and not covered by the MOCA Minute were analyzed separately. Six hundred sixteen diplomates in July 2014 and 684 diplomates in January 2015 took the CE for the first time. In multiple regression analysis, those actively participating scored 9.9 points (95% CI, 0.8 to 18.9) and 9.3 points (95% CI, 2.3 to 16.3) higher when compared with those not enrolled, respectively. Compared to the group that did not enroll in MOCA Minute, those who enrolled but did not actively participate demonstrated no improvement in scores. MOCA Minute participation was associated with improvement in both questions covering topics included the MOCA Minute and questions not covering these topics. This analysis provides evidence that voluntary active participation in a program featuring frequent knowledge assessments accompanied by targeted learning resources is associated with improved performance on a high-stakes CE.

  13. Retreatment Rates Among Endometriosis Patients Undergoing Hysterectomy or Laparoscopy.

    PubMed

    Soliman, Ahmed M; Du, Ella Xiaoyan; Yang, Hongbo; Wu, Eric Q; Haley, Jane C

    2017-06-01

    Hysterectomy and laparoscopy are the two most common surgical options used to treat women with endometriosis, yet the disease may still recur. This study aimed to determine the long-term retreatment rates among endometriosis patients in the United States who received either hysterectomy or laparoscopy. Patients aged 18-49 years with endometriosis who underwent hysterectomy or laparoscopy were identified in the Truven Health MarketScan claims database (2004-2013). The retreatment rate up to 8 years after the initial surgery was estimated using Kaplan-Meier survival analysis. The relative risk of retreatment among patients with hysterectomy versus laparoscopy was assessed using a Cox proportional hazard model. A total of 24,915 patients with endometriosis who underwent hysterectomy and 37,308 patients with endometriosis who underwent laparoscopy were identified. The estimated retreatment rates were 3.3%, 4.7%, and 5.4% in the 2nd, 5th, and 8th year following hysterectomy, respectively, while the rates following laparoscopy were 15.8%, 27.5%, and 35.2%, respectively. The hazard ratio of retreatment was 0.157 (95% confidence interval [CI]: 0.146-0.169) comparing hysterectomy to laparoscopy. In the sensitivity analysis, which expanded the definition of retreatment by including medical treatments, the retreatment rate increased by a factor of 11-14 for the hysterectomy cohort and by a factor of 2-4 for the laparoscopy cohort, and the hazard ratio of retreatment rate for hysterectomy versus laparoscopy was 0.490 (95% CI: 0.477-0.502). Our study results indicated that the disease retreatment rate after laparoscopy is high among patients with endometriosis; even hysterectomy does not guarantee freedom from retreatment.

  14. Professional Writing Retreat Handbook: A How-To Manual for Replicating the NWP Professional Writing Retreat Model

    ERIC Educational Resources Information Center

    Check, Joseph; Fox, Tom; O'Shaughnessy, Kathleen; Tateishi, Carol

    2007-01-01

    The National Writing Project designed the Professional Writing Retreats to support writing by teacher-leaders for audiences of scholars, practitioners, policymakers, and other members of the public who have an interest in education. These writing retreats focus on writing about the profession of teaching, giving teachers a chance to write about…

  15. Do Higher 20th Century Sea-cliff Retreat Rates Necessarily Imply Recent Acceleration in Sea-cliff Retreat?

    NASA Astrophysics Data System (ADS)

    Mushkin, Amit; Katz, Oded; Porat, Naomi

    2017-04-01

    Inland retreat of sea cliffs in response to post LGM (last glacial maximum) sea-level rise is an ongoing process that affects coastal environments and communities worldwide. Here, we examine a globally recurring pattern where reported sea-cliff retreat rates since the 20th century often appear to exceed longer-term millennial-scale ('background') rates that rarely exceed 0.1 m/yr. Focusing on Israel's 30-km-long Mediterranean 'Sharon' sea-cliff as a case study we demonstrate that such apparent increase in rates may also reflect a widely acknowledged sampling bias in geologic rate estimates inferred from observation time windows ('OTW') shorter than process episodicity. We show that this possible bias leads to an ambiguity in conventional rate estimates obtained by averaging observed retreat distances over OTW, and that as a result despite ubiquitous and robust observations of cliff retreat since the 20th century (e.g., aerial photographs) recent/current retreat rates for many of the world's episodically retreating sea cliffs remain essentially unknown. To address this present limitation in our ability to detect and quantify recent changes in sea-cliff retreat rates we use airborne LiDAR to measure the continuous wave-driven volumetric erosion of collapsed material from the cliff base as an effective upper-bound constraint for the m/yr rate of episodic retreat of the cliff itself. We find that while conventional retreat rate estimates since the 20th century along the Sharon sea cliff artefactually increase up to several m/yr as an inverse function of OTW, the LiDAR-constrained retreat rates are not susceptible to this sampling bias, are comparable to the cliff's background retreat rate of 0.03-0.07 m/yr since the mid Holocene and thus indicate no recent acceleration in retreat. This ability to unambiguously constrain sea-cliff retreat rates with annual to decadal-scale observations directly impacts the global-scale push to quantify, better understand and ultimately

  16. Student Leadership Retreat Focusing on a Commitment to Excellence

    PubMed Central

    Traynor, Andrew P.; Sorensen, Todd D.

    2009-01-01

    Objective To design and evaluate a student leadership retreat focused on: leadership regardless of position or title, the need for passionate commitment to excellence, the importance of teamwork, and the value of self-reflection. Design Students in their second, third, and fourth year of a doctor of pharmacy (PharmD) program were invited to participate in an off-campus leadership retreat that combined organized learning activities and social/networking opportunities. Retreat content utilized didactic, experiential, and self-directed learning activities. Assessment Forty-two students participated in the retreat and were surveyed pre- and post-retreat. A student-led group evaluation and course evaluations were also utilized. Responses on the post-retreat evaluation suggested an increased belief in their ability to influence change and an enhanced awareness of the role of self-reflection in creating excellence in the profession. Conclusion An off-campus overnight retreat has value in challenging student perceptions about leadership and promoting reflection on their personal role in leading change within the profession Continued exploration and development of this format is warranted for commitment to excellence programming and also for additional leadership topics and audiences. PMID:19564991

  17. Effect of retreatment on the end-stage sudden deafness.

    PubMed

    Suoqiang, Zhai; Ning, Yu; Guiliang, Zheng; Yuhua, Zhu; He, Qin

    2012-03-01

    Microcirculatory disturbance of inner ear is probably one of the important etiological factors of sudden deafness. The purpose of this study was to evaluate the effect of retreatment on the end-stage sudden deafness. For this purpose, the patients who met with the criteria for sudden deafness and showed poor response to conventional therapy over 2 months were assigned randomly to the retreatment group. Pure tone audiometry was conducted before and after retreatment among the 103 patients (112 ears). Sodium bicarbonate and dexamethasone were injected by intravenous drip for 2 days and batroxobin 5BU for 6 days. Data were analyzed using analysis of variance and t test to determine the efficacy of retreatment. These data show that the efficacy rate in retreatment group was 46.43% and the difference between before and after retreatment was significant (P < 0.01). It was, therefore, concluded that retreatment of the end-stage sudden deafness could improve the audition of the patients and should be valuable in clinics. In this regard, the combination of sodium bicarbonate and dexamethasone proved a rational therapeutic regimen for the end-stage sudden deafness. However, further large-size multicenter studies will be required for independent validation of these findings.

  18. How and why do patients with Type 1 diabetes sustain their use of flexible intensive insulin therapy? A qualitative longitudinal investigation of patients' self-management practices following attendance at a Dose Adjustment for Normal Eating (DAFNE) course.

    PubMed

    Rankin, D; Cooke, D D; Clark, M; Heller, S; Elliott, J; Lawton, J

    2011-05-01

    Conventional insulin therapy requires patients with Type 1 diabetes to adhere to rigid dietary and insulin injection practices. Recent trends towards flexible intensive insulin therapy enable patients to match insulin to dietary intake and lifestyle; however, little work has examined patients' experiences of incorporating these practices into real-life contexts. This qualitative longitudinal study explored patients' experiences of using flexible intensive insulin therapy to help inform the development of effective long-term support. Semi-structured interviews were conducted with 30 adult patients with Type 1 diabetes following participation in a structured education programme on using flexible intensive insulin therapy, and 6 and 12 months post-course. Longitudinal data analysis used an inductive, thematic approach. Patients consistently reported feeling committed to and wanting to sustain flexible intensive insulin therapy. This regimen was seen as a logical and effective method of self-management, as patients experienced improved blood glucose readings and/or reported feeling better. Implementing and sustaining flexible intensive insulin therapy was enhanced when patients had stable routines, with more challenges reported by those working irregular hours and during weekends/holidays. Some patients re-crafted their lives to make this approach work for them; for instance, by creating dietary routines or adjusting dietary choices. Clinical data have shown that flexible intensive insulin therapy can lead to improvement in glycaemic control. This study, drawing on patients' perspectives, provides further endorsement for flexible intensive insulin therapy by demonstrating patients' liking of, and their motivation to sustain, this approach over time. To help patients implement and sustain flexible intensive insulin therapy, follow-up support should encourage them to identify routines to better integrate this regimen into their lives. © 2011 The Authors. Diabetic

  19. Signatures of Glacial Erosion and Retreat in the Landscape: Cosmogenic and Numerical Modeling Constraints

    NASA Astrophysics Data System (ADS)

    Ward, D. J.; Anderson, R. S.; Briner, J. P.; Guido, Z. S.

    2006-12-01

    The response of glaciers to past climatic change is important for understanding 1) observations of modern glaciers under currently changing climate conditions, and 2) long-term effects on the landscape of repeated glacial occupation and retreat. The complex dynamics of these systems require that multiple lines of data constrain models of glacial behavior and erosion. Toward this end, we use cosmogenic radionuclide (CRN) exposure ages to constrain numerical simulations of glacier advance and retreat histories in the Middle Boulder Creek drainage, Colorado Front Range, and the Animas River valley, San Juan Mountains, Colorado. We present ~12 new 10Be exposure ages from glacially polished bedrock sampled in the Middle Boulder Creek valley. All of these ages are younger than a ~17 ka 10Be terminal moraine age reported by Schildgen and Dethier (2002). Ages appear to decrease monotonically with distance upvalley from the moraine, and the youngest ages in the uppermost valley are uniformly ~10 ka. We include 5 10Be ages in a cross section across the mid-valley, which show a pattern of Last Glacial Maximum (LGM) ages (11-14 ka) within the glacial footprint, and older exposure ages (~40 ka) near the trim lines. A similar age trend is seen in the Animas River valley in southwestern Colorado, which was occupied by a lobe of the LGM ice sheet that capped the San Juan mountains. Deglaciation began here ca. 18.7 ka, based on a 10Be depth profile in a proglacial terrace. A longitudinal transect of exposure ages from glacially polished samples indicates that terminus retreat proceeded at 6-9 m/yr until complete deglaciation ca. 9.5 ka. Neither valley has obvious recessional deposits within the LGM glacial footprint. The first-order trend in each valley is a monotonic glacial retreat, but there are other possible retreat scenarios. For instance, we would like to test whether the same trend in 10Be concentrations could be generated by episodic retreat punctuated by periods of

  20. Magnetic Reconnection by a Self-Retreating X Line

    SciTech Connect

    Oka, M.; Nishikawa, K.-I.; Fujimoto, M.; Nakamura, T. K. M.; Shinohara, I.

    2008-11-14

    Particle-in-cell simulations of collisionless magnetic reconnection are performed to study asymmetric reconnection in which an outflow is blocked by a hard wall while leaving sufficiently large room for the outflow of the opposite direction. This condition leads to a slow, roughly constant motion of the diffusion region away from the wall, the so-called 'X-line retreat'. The typical retreat speed is {approx}0.1 times the Alfven speed. At the diffusion region, ion flow pattern shows strong asymmetry and the ion stagnation point and the X line are not collocated. A surprise, however, is that the reconnection rate remains the same unaffected by the retreat motion.

  1. Do Wellness Tourists Get Well? An Observational Study of Multiple Dimensions of Health and Well-Being After a Week-Long Retreat

    PubMed Central

    Elliott, Fiona; Oates, Liza; Schembri, Adrian; Mantri, Nitin

    2017-01-01

    Abstract Background: Wellness retreats use many complementary and alternative therapies within a holistic residential setting, yet few studies have evaluated the effect of retreat experiences on multiple dimensions of health and well-being, and no published studies have reported health outcomes in wellness tourists. Objectives: To assess the effect of a week-long wellness-retreat experience in wellness tourists. Design: A longitudinal observational study with outcomes assessed upon arrival and departure and 6 weeks after the retreat. Setting: A rural health retreat in Queensland, Australia. Interventions: A holistic, 1-week, residential, retreat experience that included many educational, therapeutic, and leisure activities and an organic, mostly plant-based diet. Outcome measures: Multiple outcome measures were performed upon arrival and departure and 6 weeks after the retreat. These included anthropometric measures, urinary pesticide metabolites, a food and health symptom questionnaire, the Five Factor Wellness Inventory, the General Self Efficacy questionnaire, the Pittsburgh Insomnia Rating Scale, the Depression Anxiety Stress Scale, the Profile of Mood States, and the Cogstate cognitive function test battery. Results: Statistically significant improvements (p < 0.05) were seen in almost all measures (n = 37) after 1 week and were sustained at 6 weeks (n = 17). There were statistically significant improvements (p < 0.001) in all anthropometric measures after 1 week, with reductions in abdominal girth (2.7 cm), weight (1.6 kg), and average systolic and diastolic pressure (−16.1 mmHg and −9.3 mmHg, respectively). Statistically significant improvements (p < 0.05) were also seen in psychological and health symptom measures. Urinary pesticide metabolites were detected in pooled urine samples before the retreat and were undetectable after the retreat. Conclusion: Retreat experiences can lead to substantial improvements in multiple

  2. Do Wellness Tourists Get Well? An Observational Study of Multiple Dimensions of Health and Well-Being After a Week-Long Retreat.

    PubMed

    Cohen, Marc M; Elliott, Fiona; Oates, Liza; Schembri, Adrian; Mantri, Nitin

    2017-02-01

    Wellness retreats use many complementary and alternative therapies within a holistic residential setting, yet few studies have evaluated the effect of retreat experiences on multiple dimensions of health and well-being, and no published studies have reported health outcomes in wellness tourists. To assess the effect of a week-long wellness-retreat experience in wellness tourists. A longitudinal observational study with outcomes assessed upon arrival and departure and 6 weeks after the retreat. A rural health retreat in Queensland, Australia. A holistic, 1-week, residential, retreat experience that included many educational, therapeutic, and leisure activities and an organic, mostly plant-based diet. Multiple outcome measures were performed upon arrival and departure and 6 weeks after the retreat. These included anthropometric measures, urinary pesticide metabolites, a food and health symptom questionnaire, the Five Factor Wellness Inventory, the General Self Efficacy questionnaire, the Pittsburgh Insomnia Rating Scale, the Depression Anxiety Stress Scale, the Profile of Mood States, and the Cogstate cognitive function test battery. Statistically significant improvements (p < 0.05) were seen in almost all measures (n = 37) after 1 week and were sustained at 6 weeks (n = 17). There were statistically significant improvements (p < 0.001) in all anthropometric measures after 1 week, with reductions in abdominal girth (2.7 cm), weight (1.6 kg), and average systolic and diastolic pressure (-16.1 mmHg and -9.3 mmHg, respectively). Statistically significant improvements (p < 0.05) were also seen in psychological and health symptom measures. Urinary pesticide metabolites were detected in pooled urine samples before the retreat and were undetectable after the retreat. Retreat experiences can lead to substantial improvements in multiple dimensions of health and well-being that are maintained for 6 weeks. Further research that includes objective

  3. Parental engagement and early interactions with preterm infants during the stay in the neonatal intensive care unit: protocol of a mixed-method and longitudinal study

    PubMed Central

    Stefana, Alberto; Lavelli, Manuela

    2017-01-01

    Introduction The preterm infants' developmental outcomes depend on biological and environmental risk factors. The environmental factors include prolonged parental separation, less exposure to early mother/father–infant interactions and the parents' ability to respond to the trauma of premature birth. In the case of premature birth, the father's ability to take an active part in the care of the infant from the start is essential. The parents' emotional closeness to the preterm infant hospitalised in the neonatal intensive care unit (NICU) may be crucial to the well-being of the newborn, the development of mutual regulation, the establishment of a functioning parent–infant affective relationship and the parents' confidence in their ability to provide care for their baby. Methods and analysis This is a mixed-method, observational and longitudinal study. The methodological strategy will include: (1) ethnographic observation in a level III NICU located in Italy for a duration of 18 months; (2) 3-minute video recordings of mother–infant and father–infant interaction in the NICU; (3) a semistructured interview with fathers during the infants' hospital stay; (4) 3-minute video recordings of mother–infant and father–infant face-to-face interaction in the laboratory at 4 months of corrected age; (5) self-report questionnaires for parents on depression and quality of the couple relationship at the approximate times of the video recording sessions. Ethics and dissemination The study protocol was approved by the Ethical Committee for Clinical Trials of the Verona and Rovigo Provinces. Results aim to be published in international peer-reviewed journals, and presented at relevant national and international conferences. This research project will develop research relevant to (1) the quality and modalities of maternal and paternal communication with the preterm infant in the NICU; (2) the influence of maternal/paternal social stimulation on the infant behavioural

  4. Level of Cigarette Consumption and Quit Behavior in a Population of Low-Intensity Smokers – Longitudinal Results from the International Tobacco Control (ITC) Survey in Mexico

    PubMed Central

    Swayampakala, Kamala; Thrasher, James; Carpenter, Matthew J.; Shigematsu, Luz Myriam Reynales; Cupertio, Ana-Paula; Berg, Carla J.

    2013-01-01

    Background Mexican smokers are more likely to be non-daily smokers and to consume fewer cigarettes per day than smokers in other countries. Little is known about their quit behaviors. Aim The aim of this study is to determine factors associated with having made a quit attempt and being successfully quit at 14-month follow-up in a population-based cohort of adult Mexicans who smoke at different levels of intensity. Design A longitudinal analysis of wave-III and wave-IV (2010) Mexican administration of International Tobacco Control Policy Evaluation Project was conducted. Setting This study was conducted in six large urban centers in Mexico Participants The participants of this study comprised 1206 adults who were current smokers at wave-III and 41 who were followed to wave-IV. Measurements We compared three groups of smokers: non-daily smokers—who did not smoke every day in the past 30 days (n=398), daily light smokers who smoked every day at a rate of ≤5 cigarettes per day. Data on smoking behavior, psychosocial characteristics and socio-demographics were collected at baseline and after 14 months. Findings In multivariate logistic regression predicting having made a quit attempt at follow-up, significant factors included being a non-daily smoker versus a heavy daily smoker (ORadj = 1.83, 95%CI: 1.19–2.83), less perceived addiction ((ORadj = 1.86, 95%CI: 1.20 – 2.87), greater worry that cigarettes will damage health (ORadj = 2.04, 95%CI: 1.16 – 3.61) and having made a quit attempt in the past year at baseline (ORadj = 1.70, 95%CI: 1.23 – 2.36). In multivariate logistic regression predicting being successfully quit at one-year follow-up, significant factors included being a non-daily smoker versus a heavy daily smoker (ORadj = 2.54, 95%CI: 1.37–4.70) and less perceived addiction (not addicted: ORadj = 3.26, 95%CI: 1.73 – 6.14; not much: ORadj = 1.95, 95%CI: 1.05 – 3.62 versus very much). Conclusions Mexican adult smokers who are non-daily smokers

  5. Patient-Reported Voice and Speech Outcomes After Whole-Neck Intensity Modulated Radiation Therapy and Chemotherapy for Oropharyngeal Cancer: Prospective Longitudinal Study

    SciTech Connect

    Vainshtein, Jeffrey M.; Griffith, Kent A.; Feng, Felix Y.; Vineberg, Karen A.; Chepeha, Douglas B.; Eisbruch, Avraham

    2014-08-01

    Purpose: To describe voice and speech quality changes and their predictors in patients with locally advanced oropharyngeal cancer treated on prospective clinical studies of organ-preserving chemotherapy–intensity modulated radiation therapy (chemo-IMRT). Methods and Materials: Ninety-one patients with stage III/IV oropharyngeal cancer were treated on 2 consecutive prospective studies of definitive chemoradiation using whole-field IMRT from 2003 to 2011. Patient-reported voice and speech quality were longitudinally assessed from before treatment through 24 months using the Communication Domain of the Head and Neck Quality of Life (HNQOL-C) instrument and the Speech question of the University of Washington Quality of Life (UWQOL-S) instrument, respectively. Factors associated with patient-reported voice quality worsening from baseline and speech impairment were assessed. Results: Voice quality decreased maximally at 1 month, with 68% and 41% of patients reporting worse HNQOL-C and UWQOL-S scores compared with before treatment, and improved thereafter, recovering to baseline by 12-18 months on average. In contrast, observer-rated larynx toxicity was rare (7% at 3 months; 5% at 6 months). Among patients with mean glottic larynx (GL) dose ≤20 Gy, >20-30 Gy, >30-40 Gy, >40-50 Gy, and >50 Gy, 10%, 32%, 25%, 30%, and 63%, respectively, reported worse voice quality at 12 months compared with before treatment (P=.011). Results for speech impairment were similar. Glottic larynx dose, N stage, neck dissection, oral cavity dose, and time since chemo-IMRT were univariately associated with either voice worsening or speech impairment. On multivariate analysis, mean GL dose remained independently predictive for both voice quality worsening (8.1%/Gy) and speech impairment (4.3%/Gy). Conclusions: Voice quality worsening and speech impairment after chemo-IMRT for locally advanced oropharyngeal cancer were frequently reported by patients, underrecognized by clinicians, and

  6. Patient-reported voice and speech outcomes after whole-neck intensity modulated radiation therapy and chemotherapy for oropharyngeal cancer: prospective longitudinal study.

    PubMed

    Vainshtein, Jeffrey M; Griffith, Kent A; Feng, Felix Y; Vineberg, Karen A; Chepeha, Douglas B; Eisbruch, Avraham

    2014-08-01

    To describe voice and speech quality changes and their predictors in patients with locally advanced oropharyngeal cancer treated on prospective clinical studies of organ-preserving chemotherapy-intensity modulated radiation therapy (chemo-IMRT). Ninety-one patients with stage III/IV oropharyngeal cancer were treated on 2 consecutive prospective studies of definitive chemoradiation using whole-field IMRT from 2003 to 2011. Patient-reported voice and speech quality were longitudinally assessed from before treatment through 24 months using the Communication Domain of the Head and Neck Quality of Life (HNQOL-C) instrument and the Speech question of the University of Washington Quality of Life (UWQOL-S) instrument, respectively. Factors associated with patient-reported voice quality worsening from baseline and speech impairment were assessed. Voice quality decreased maximally at 1 month, with 68% and 41% of patients reporting worse HNQOL-C and UWQOL-S scores compared with before treatment, and improved thereafter, recovering to baseline by 12-18 months on average. In contrast, observer-rated larynx toxicity was rare (7% at 3 months; 5% at 6 months). Among patients with mean glottic larynx (GL) dose ≤20 Gy, >20-30 Gy, >30-40 Gy, >40-50 Gy, and >50 Gy, 10%, 32%, 25%, 30%, and 63%, respectively, reported worse voice quality at 12 months compared with before treatment (P=.011). Results for speech impairment were similar. Glottic larynx dose, N stage, neck dissection, oral cavity dose, and time since chemo-IMRT were univariately associated with either voice worsening or speech impairment. On multivariate analysis, mean GL dose remained independently predictive for both voice quality worsening (8.1%/Gy) and speech impairment (4.3%/Gy). Voice quality worsening and speech impairment after chemo-IMRT for locally advanced oropharyngeal cancer were frequently reported by patients, underrecognized by clinicians, and independently associated with GL dose. These findings support

  7. Means of Slope Retreat on the Na Pali Cliffs, Kauai, Hawaii

    NASA Astrophysics Data System (ADS)

    Osborn, G.; Sheardown, A.; Blay, C.

    2016-12-01

    The spectacular, 500 to 600 m high, deeply grooved escarpment referred to as the Na Pali cliffs, on the northwest coast of Kauai, requires a substrate competent enough to hold up high steep cliffs yet erodible enough to allow generation of wide, deep grooves. These opposing tendencies are afforded by weathering of originally strong basalt that keeps pace with erosion. The fluted cliffs maintain a rather consistent slope angle, generally 50-60°, whether they are close to the shoreline or have retreated some distance from it, indicating that the slopes are retreating parallel to themselves. Previous literature promotes groundwater sapping or waterfall-plunge-pool erosion as the chief means of valley-head retreat, but there is no evidence that either concept provides a general explanation for retreat of the fluted cliffs. The eroding cliffs maintain steepness because as much rock is eroded at the base as at the top, and transported sediment is washed completely out of the gully system. The thin-bedded basalts exposed in the steep flutes are decomposed into irregularly alternating fine sediment of low to moderate cohesion and thoroughly fractured beds or lenses of solid but chemically weathered rock, and covered with a veneer of sparse grass. Erosion proceeds by episodic removal of thin grass-covered surficial sheets of the weathering products. Some of this process may be facilitated by shallow mass movement, but probably most of the work is done by overland and channelized flow during intense rainstorms. The Na Pali coast experiences one-hour rainfalls of 2-2.5 inches (1 year recurrence interval) and 5-6 inches (100 year recurrence interval); experiments by others on basaltic soils in Molokai suggest such rain is more than enough to generate erosion-inducing overland flow. Between the deep grooves and the shoreline are slopes with lesser drainage densities and lesser slope angles. The rocks here are not distinguished from the rocks above in previous literature, and

  8. Greenland's pronounced glacier retreat not irreversible

    NASA Astrophysics Data System (ADS)

    Schultz, Colin

    2012-02-01

    In recent decades, the combined forces of climate warming and short-term variability have forced the massive glaciers that blanket Greenland into retreat, with some scientists worrying that deglaciation could become irreversible. The short history of detailed glacier observations, however, makes pinning the ice loss to either short-term dynamics or long-term change difficult. Research by Young et al. detailing the effects of two bouts of sudden and temporary cooling during an otherwise warm phase in Greenland's climate history could help answer that question by showing just how heavy a hand short-term variability can have in dictating glacier dynamics. Along the western edge of Greenland the massive Jakobshavn Isbræ glacier reaches out to the coast, its outflow dropping icebergs into Baffin Bay during the summer months. Flanking the glacier's tongue are the Tasiussaq and Marrait moraines—piles of rock marking the glacier's former extent. Researchers suspected the moraines were tied to two periods of abrupt cooling that hit Greenland 9300 and 8200 years ago, and that association was reinforced by the authors' radiocarbon and beryllium isotope analyses of the area surrounding the moraines. Beryllium-10 forms when cosmic radiation travels through the atmosphere and strikes the Earth's surface, with surface rock concentrations indicating how long it has been ice-free.

  9. MTA monoblock obturation technique in endodontic retreatment.

    PubMed

    Iqbal, Zahid; Qureshi, Abdul Hakeem

    2014-11-01

    A 48-year-old male patient presented to the Department of Endodontics for evaluation of right first permanent molar, which had received non-surgical root canal treatment two years ago and was restored with core material. The presenting symptoms included swelling in the buccal vestibule and pain overnight. Clinical examination demonstrated that the mandibular right first molar was sensitive to percussion and also showed fluctuant swelling in the vestibule proximal to the molar and mild mobility. Radiographic examination revealed a poor quality obturation of the mesial and distal root, distal root resorption, extensive periapical and furcation radiolucency and bone loss. A diagnosis of acute periapical abscess of the mandibular right first molar was made. Tooth was treated non-surgically by the manual application of MTA in the root canal. Follow-up evaluation was performed at one year after the treatment. Clinically, treatment was considered successful due to the absence of clinical signs, symptoms and radiographic appearance with substantial reduction (more than 50%) in the diameter of the periapical radiolucency. Mineral trioxide aggregate monoblock obturation technique appears to be a valid technique to obtain periradicular healing in re-treatment of previously root canal treated teeth with periapical lesion.

  10. Seaweed communities in retreat from ocean warming.

    PubMed

    Wernberg, Thomas; Russell, Bayden D; Thomsen, Mads S; Gurgel, C Frederico D; Bradshaw, Corey J A; Poloczanska, Elvira S; Connell, Sean D

    2011-11-08

    In recent decades, global climate change [1] has caused profound biological changes across the planet [2-6]. However, there is a great disparity in the strength of evidence among different ecosystems and between hemispheres: changes on land have been well documented through long-term studies, but similar direct evidence for impacts of warming is virtually absent from the oceans [3, 7], where only a few studies on individual species of intertidal invertebrates, plankton, and commercially important fish in the North Atlantic and North Pacific exist. This disparity of evidence is precarious for biological conservation because of the critical role of the marine realm in regulating the Earth's environmental and ecological functions, and the associated socioeconomic well-being of humans [8]. We interrogated a database of >20,000 herbarium records of macroalgae collected in Australia since the 1940s and documented changes in communities and geographical distribution limits in both the Indian and Pacific Oceans, consistent with rapid warming over the past five decades [9, 10]. We show that continued warming might drive potentially hundreds of species toward and beyond the edge of the Australian continent where sustained retreat is impossible. The potential for global extinctions is profound considering the many endemic seaweeds and seaweed-dependent marine organisms in temperate Australia.

  11. Calculating lunar retreat rates using tidal rhythmites

    USGS Publications Warehouse

    Kvale, E.P.; Johnson, H.W.; Sonett, C.P.; Archer, A.W.; Zawistoski, A.N.N.

    1999-01-01

    Tidal rhythmites are small-scale sedimenta??r}- structures that can preserve a hierarchy of astronomically induced tidal periods. They can also preserve a record of periodic nontidal sedimentation. If properly interpreted and understood, tidal rhjthmites can be an important component of paleoastronomy and can be used to extract information on ancient lunar orbital dynamics including changes in Earth-Moon distance through geologic time. Herein we present techniques that can be used to calculate ancient Earth-Moon distances. Each of these techniques, when used on a modern high-tide data set, results in calculated estimates of lunar orbital periods and an EarthMoon distance that fall well within 1 percent of the actual values. Comparisons to results from modern tidal data indicate that ancient tidal rhythmite data as short as 4 months can provide suitable estimates of lunar orbital periods if these tidal records are complete. An understanding of basic tidal theory allows for the evaluation of completeness of the ancient tidal record as derived from an analysis of tidal rhythmites. Utilizing the techniques presented herein, it appears from the rock record that lunar orbital retreat slowed sometime during the midPaleozoic. Copyright ??1999, SEPM (Society for Sedimentary Geology).

  12. Endodontic procedures for retreatment of periapical lesions.

    PubMed

    Del Fabbro, Massimo; Corbella, Stefano; Sequeira-Byron, Patrick; Tsesis, Igor; Rosen, Eyal; Lolato, Alessandra; Taschieri, Silvio

    2016-10-19

    When primary root canal therapy fails, periapical lesions can be retreated with or without surgery. Root canal retreatment is a non-surgical procedure that involves removal of root canal filling materials from the tooth, followed by cleaning, shaping and obturating of the canals. Root-end resection is a surgical procedure that involves exposure of the periapical lesion through an osteotomy, surgical removal of the lesion, removal of part of the root-end tip, disinfection and, commonly, retrograde sealing or filling of the apical portion of the remaining root canal. This review updates one published in 2008. To assess effects of surgical and non-surgical therapy for retreatment of teeth with apical periodontitis.To assess effects of surgical root-end resection under various conditions, for example, when different materials, devices or techniques are used. We searched the following electronic databases: the Cochrane Oral Health Trials Register (to 10 February 2016), the Cochrane Central Register of Controlled Trials (CENTRAL; 2016, Issue 1), MEDLINE Ovid (1946 to 10 February 2016) and Embase Ovid (1980 to 10 February 2016). We searched the US National Registry of Clinical Trials (ClinicalTrials.gov) and the World Health Organization (WHO) International Clinical Trials Registry Platform for ongoing trials (to 10 February 2016). We placed no restrictions regarding language and publication date. We handsearched the reference lists of the studies retrieved and key journals in the field of endodontics. We included randomised controlled trials (RCTs) involving people with periapical pathosis. Studies could compare surgery versus non-surgical treatment or could compare different types of surgery. Outcome measures were healing of the periapical lesion assessed after one-year follow-up or longer; postoperative pain and discomfort; and adverse effects such as tooth loss, mobility, soft tissue recession, abscess, infection, neurological damage or loss of root sealing material

  13. Climate change and glacier retreat drive shifts in an Antarctic benthic ecosystem.

    PubMed

    Sahade, Ricardo; Lagger, Cristian; Torre, Luciana; Momo, Fernando; Monien, Patrick; Schloss, Irene; Barnes, David K A; Servetto, Natalia; Tarantelli, Soledad; Tatián, Marcos; Zamboni, Nadia; Abele, Doris

    2015-11-01

    The Antarctic Peninsula (AP) is one of the three places on Earth that registered the most intense warming in the last 50 years, almost five times the global mean. This warming has strongly affected the cryosphere, causing the largest ice-shelf collapses ever observed and the retreat of 87% of glaciers. Ecosystem responses, although increasingly predicted, have been mainly reported for pelagic systems. However, and despite most Antarctic species being benthic, responses in the Antarctic benthos have been detected in only a few species, and major effects at assemblage level are unknown. This is probably due to the scarcity of baselines against which to assess change. We performed repeat surveys of coastal benthos in 1994, 1998, and 2010, analyzing community structure and environmental variables at King George Island, Antarctica. We report a marked shift in an Antarctic benthic community that can be linked to ongoing climate change. However, rather than temperature as the primary factor, we highlight the resulting increased sediment runoff, triggered by glacier retreat, as the potential causal factor. The sudden shift from a "filter feeders-ascidian domination" to a "mixed assemblage" suggests that thresholds (for example, of tolerable sedimentation) and alternative equilibrium states, depending on the reversibility of the changes, could be possible traits of this ecosystem. Sedimentation processes will be increasing under the current scenario of glacier retreat, and attention needs to be paid to its effects along the AP.

  14. Climate change and glacier retreat drive shifts in an Antarctic benthic ecosystem

    PubMed Central

    Sahade, Ricardo; Lagger, Cristian; Torre, Luciana; Momo, Fernando; Monien, Patrick; Schloss, Irene; Barnes, David K. A.; Servetto, Natalia; Tarantelli, Soledad; Tatián, Marcos; Zamboni, Nadia; Abele, Doris

    2015-01-01

    The Antarctic Peninsula (AP) is one of the three places on Earth that registered the most intense warming in the last 50 years, almost five times the global mean. This warming has strongly affected the cryosphere, causing the largest ice-shelf collapses ever observed and the retreat of 87% of glaciers. Ecosystem responses, although increasingly predicted, have been mainly reported for pelagic systems. However, and despite most Antarctic species being benthic, responses in the Antarctic benthos have been detected in only a few species, and major effects at assemblage level are unknown. This is probably due to the scarcity of baselines against which to assess change. We performed repeat surveys of coastal benthos in 1994, 1998, and 2010, analyzing community structure and environmental variables at King George Island, Antarctica. We report a marked shift in an Antarctic benthic community that can be linked to ongoing climate change. However, rather than temperature as the primary factor, we highlight the resulting increased sediment runoff, triggered by glacier retreat, as the potential causal factor. The sudden shift from a “filter feeders–ascidian domination” to a “mixed assemblage” suggests that thresholds (for example, of tolerable sedimentation) and alternative equilibrium states, depending on the reversibility of the changes, could be possible traits of this ecosystem. Sedimentation processes will be increasing under the current scenario of glacier retreat, and attention needs to be paid to its effects along the AP. PMID:26702429

  15. Plasticity of visual attention in Isha yoga meditation practitioners before and after a 3-month retreat.

    PubMed

    Braboszcz, Claire; Cahn, B Rael; Balakrishnan, Bhavani; Maturi, Raj K; Grandchamp, Romain; Delorme, Arnaud

    2013-01-01

    Meditation has lately received considerable interest from cognitive neuroscience. Studies suggest that daily meditation leads to long lasting attentional and neuronal plasticity. We present changes related to the attentional systems before and after a 3 month intensive meditation retreat. We used three behavioral psychophysical tests - a Stroop task, an attentional blink task, and a global-local letter task-to assess the effect of Isha yoga meditation on attentional resource allocation. 82 Isha yoga practitioners were tested at the beginning and at the end of the retreat. Our results showed an increase in correct responses specific to incongruent stimuli in the Stroop task. Congruently, a positive correlation between previous meditation experience and accuracy to incongruent Stroop stimuli was also observed at baseline. We also observed a reduction of the attentional blink. Unexpectedly, a negative correlation between previous meditation experience and attentional blink performance at baseline was observed. Regarding spatial attention orientation as assessed using the global-local letter task, participants showed a bias toward local processing. Only slight differences in performance were found pre- vs. post- meditation retreat. Biasing toward the local stimuli in the global-local task and negative correlation of previous meditation experience with attentional blink performance is consistent with Isha practices being focused-attention practices. Given the relatively small effect sizes and the absence of a control group, our results do not allow clear support nor rejection of the hypothesis of meditation-driven neuronal plasticity in the attentional system for Isha yoga practice.

  16. [The application of desocclusol and manual mechanical method in endodontic retreatment].

    PubMed

    Zhao, Ai-min; Zhang, Hai-liang; Ou, Xiao-yan

    2011-12-01

    To investigate the clinical method to remove a gutta-percha and root canal sealers. 168 root canals which had been filled with gutta-percha were selected,all root canals needed endodontic retreatment.The root canal fillings were removed and the root canal was re-prepared with the method of desocclusol and manual mechanical method. Then the root canal was filled again with lateral condensation technique. With manual mechanical method and desocclusol,all original root canal fillings were removed completely. The combined method could effectively prevent the formation of step,root canal-side wear,broken equipment or other complications during the course of retreatment.The success rate of retreatment was 89.3%. Combined manual mechanical method with desocclusol could improve the success rate of recanalization of the root canal and saved time and effort. It is a method which could reduce the intensity and improve the efficiency of dentists, and worthy of wide clinical application.

  17. Rituximab Retreatment for Low-Tumor Burden Follicular Lymphoma

    Cancer.gov

    A summary of results from a randomized clinical trial of patients with low–tumor burden follicular lymphoma that compared maintenance therapy with rituximab versus retreatment with rituximab only when there was evidence of disease progression.

  18. Centennial glacier retreat as categorical evidence of regional climate change

    NASA Astrophysics Data System (ADS)

    Roe, Gerard H.; Baker, Marcia B.; Herla, Florian

    2016-12-01

    The near-global retreat of glaciers over the last century provides some of the most iconic imagery for communicating the reality of anthropogenic climate change to the public. Surprisingly, however, there has not been a quantitative foundation for attributing the retreats to climate change, except in the global aggregate. This gap, between public perception and scientific basis, is due to uncertainties in numerical modelling and the short length of glacier mass-balance records. Here we present a method for assessing individual glacier change based on the signal-to-noise ratio, a robust metric that is insensitive to uncertainties in glacier dynamics. Using only meteorological and glacier observations, and the characteristic decadal response time of glaciers, we demonstrate that observed retreats of individual glaciers represent some of the highest signal-to-noise ratios of climate change yet documented. Therefore, in many places, the centennial-scale retreat of the local glaciers does indeed constitute categorical evidence of climate change.

  19. Centennial glacier retreat as categorical evidence of regional climate change

    NASA Astrophysics Data System (ADS)

    Roe, Gerard H.; Baker, Marcia B.; Herla, Florian

    2017-02-01

    The near-global retreat of glaciers over the last century provides some of the most iconic imagery for communicating the reality of anthropogenic climate change to the public. Surprisingly, however, there has not been a quantitative foundation for attributing the retreats to climate change, except in the global aggregate. This gap, between public perception and scientific basis, is due to uncertainties in numerical modelling and the short length of glacier mass-balance records. Here we present a method for assessing individual glacier change based on the signal-to-noise ratio, a robust metric that is insensitive to uncertainties in glacier dynamics. Using only meteorological and glacier observations, and the characteristic decadal response time of glaciers, we demonstrate that observed retreats of individual glaciers represent some of the highest signal-to-noise ratios of climate change yet documented. Therefore, in many places, the centennial-scale retreat of the local glaciers does indeed constitute categorical evidence of climate change.

  20. Managed retreat as a response to natural hazard risk

    NASA Astrophysics Data System (ADS)

    Hino, Miyuki; Field, Christopher B.; Mach, Katharine J.

    2017-03-01

    Managed retreat is a potentially important climate change adaptation option, providing an alternative to structural protection or accommodation measures to manage natural hazard risk. However, its application faces challenges given the projected scale of climate-induced displacement and the difficulties of resettlement. We evaluate the drivers, barriers and outcomes of 27 recent cases of managed retreat that have resettled approximately 1.3 million people. A conceptual model based on two key factors--who benefits from retreat and who initiates it--organizes the diverse set of cases into four quadrants. Different sociopolitical dimensions emerge as particularly influential in each quadrant. The model establishes a foundation for understanding and anticipating case-specific complexities. It can be used to unpack the landscape of managed retreat and evaluate its potential future applications.

  1. Cooperative Spatial Retreat for Resilient Drone Networks †

    PubMed Central

    Kang, Jin-Hyeok; Kwon, Young-Min; Park, Kyung-Joon

    2017-01-01

    Drones are broadening their scope to various applications such as networking, package delivery, agriculture, rescue, and many more. For proper operation of drones, reliable communication should be guaranteed because drones are remotely controlled. When drones experience communication failure due to bad channel condition, interference, or jamming in a certain area, one existing solution is to exploit mobility or so-called spatial retreat to evacuate them from the communication failure area. However, the conventional spatial retreat scheme moves drones in random directions, which results in inefficient movement with significant evacuation time and waste of battery lifetime. In this paper, we propose a novel spatial retreat technique that takes advantage of cooperation between drones for resilient networking, which is called cooperative spatial retreat (CSR). Our performance evaluation shows that the proposed CSR significantly outperforms existing schemes. PMID:28467390

  2. A week-long meditation retreat decouples behavioral measures of the alerting and executive attention networks.

    PubMed

    Elliott, James C; Wallace, B Alan; Giesbrecht, Barry

    2014-01-01

    PREVIOUS STUDIES HAVE EXAMINED THE INFLUENCE OF MEDITATION ON THREE FUNCTIONALLY DIFFERENT COMPONENTS OF ATTENTION: executive control, alerting, and orienting. These studies have consistently found that meditation training improves both executive attention and alerting, but there has not been a consistent and clear effect of meditation training on orienting. In addition, while previous studies have shown that the functional coupling of the alerting and executive networks increases the processing of task irrelevant stimuli, it is unknown if participating in a meditation retreat can decouple these components of attention and lead to improved performance. The current study investigated the influence of a week-long intensive meditation retreat on three components of attention by randomly assigning participants to either pre- or postretreat testing groups. A modified attention network test (ANT) was used. Executive attention was measured as the difference in response time (RT) between congruent and incongruent task irrelevant flankers (conflict effect). Reflexive and volitional orienting were measured by manipulating cue validity and stimulus onset asynchrony (SOA). The coupling of executive attention and alerting was measured by examining flanker interference as a function of the SOA of an alerting cue. The meditation retreat improved task based indices of executive attention, but not reflexive or volitional orienting. There was clear behavioral evidence of coupling between executive attention and alerting in the preretreat group, as the conflict effect peaked when an alerting cue was presented 300 ms before the target. Importantly, there was no increase in the conflict effect for the postretreat group. This is consistent with the notion that the retreat decoupled the executive and alerting networks. These results suggest that previously reported improvements in the executive and alerting networks after meditation training might be mediated by the same underlying

  3. Population density of tropical forest frogs: relation to retreat sites.

    PubMed

    Stewart, M M; Pough, F H

    1983-08-05

    The forest frog Eleutherodactylus coqui defends specific sites for retreats and nests in the Luquillo Forest, Puerto Rico. The hypothesis that shortages of nest and retreat sites limit population size was tested by placing 100 bamboo frog houses in plots measuring 100 square meters in areas of high frog density. These new sites were readily adopted by adult frogs. After one year, experimental plots had significantly more nests and frogs of all sizes than did control plots.

  4. Signatures of Glacial Erosion and Retreat in the Landscape: Cosmogenic and Numerical Modeling Constraints

    NASA Astrophysics Data System (ADS)

    Ward, D. J.; Anderson, R. S.; Briner, J. P.; Guido, Z. S.

    2007-12-01

    We use cosmogenic radionuclide (CRN) exposure ages to constrain numerical simulations of deglaciation histories in the Middle Boulder Creek drainage, Colorado Front Range, and the Animas River valley, San Juan Mountains, Colorado. We present 18 new 10Be exposure ages from glacially polished bedrock sampled in the Middle Boulder Creek valley. All of these ages are younger than the ~19-22 ka terminal moraine age based on 26Al and 36Cl measurements by Schildgen (2000) and Benson et al. (2005). Exposure ages decrease with distance upvalley from the moraine, and the youngest ages in the uppermost valley are uniformly ~13 ka. We include 4 10Be ages in a cross section across the mid-valley, which show a pattern of Last Glacial Maximum (LGM) ages (12-14 ka) within the glacial footprint, and older exposure ages (~40 ka) near the trim lines. A similar age trend is seen in the Animas River valley in southwestern Colorado, which was occupied by a lobe of the LGM ice sheet that capped the San Juan mountains. Deglaciation began here ca. 19.4 ka, based on a 10Be depth profile in a proglacial terrace. A longitudinal transect of exposure ages from glacially polished samples indicates that terminus retreat proceeded at ~15 m/yr until complete deglaciation ca. 12.3 ka. Neither valley has obvious recessional deposits within the LGM glacial footprint. The first-order trend in each valley is a monotonic glacial retreat, but there are other possible retreat scenarios. For instance, we would like to test whether the same trend in 10Be concentrations could be generated by episodic retreat punctuated by periods of readvance. To investigate these scenarios, we modified the GC2D numerical glacier simulation (see Kessler et al., 2006) to incorporate a CRN accumulation layer. This layer can contain any starting value of CRN concentration. Production over each timestep is scaled to DEM latitude and altitude. Production is taken to be zero in areas covered by more than 10 m of ice. The CRN

  5. Hasty retreat of glaciers in northern Patagonia

    NASA Astrophysics Data System (ADS)

    Paul, Frank; Mölg, Nico

    2014-05-01

    decline (area and thickness loss). Some glaciers retreated more than 3 km over this time period or even disappeared completely. Typically, these glaciers lost contact to the accumulation areas of tributaries and melted away as dead ice. Furthermore, numerous proglacial lakes formed or expanded rapidly, increasing the local hazard potential. On the other hand, some glaciers located on or near to (still active) volcanoes have also slightly advanced over the same time period. Observed trends in temperature (decreasing) are in contrast to the observed strong glacier shrinkage, indicating that also other factors must play a role.

  6. Projecting 21st century coastal cliff retreat in Southern California

    NASA Astrophysics Data System (ADS)

    Limber, P. W.; Barnard, P.; Erikson, L. H.; Vitousek, S.

    2016-12-01

    In California, sea level is expected to rise over 1 m by 2100, with extreme projections approaching 3 m. Sea level rise (SLR) increases the frequency, severity, and duration of wave impacts on coastal cliffs, potentially accelerating cliff retreat rates. To assess the future risk to cliff-top infrastructure, densely populated Southern California cities like Los Angeles and San Diego require estimates of coastal retreat over long time (multi-decadal) and large spatial (>100 km) scales. We developed a suite of eight coastal cliff retreat models, ranging in complexity from empirical 1-D representations of cliff response to wave impacts to more intricate 2-D process-based models integrated with artificial neural networks. The ensemble produces a comprehensive estimate of time-averaged coastal cliff retreat with uncertainty, is applicable to different geological environments, and is flexible in application depending on processing power, available data, and/or available time (e.g. if processing power and time are limited, the fast 1-D models can be used as a `rapid assessment' tool). Global-to-local nested wave models provided the hindcasts (1980-2010) and forecasts (2010-2100) used to force the models, and waves were applied in combination with eight SLR scenarios ranging from 0.25 m to 2 m. In the more detailed models, tides, non-tidal residuals, and storm surge were included for the hindcast and forecast periods. For model calibration, a new automated cliff edge extraction routine was used to estimate historical cliff retreat rates from LiDAR data. Initial model application to Southern California suggests that 1 m of SLR during the 21st century will cause cliff retreat rates to increase on average by over 50% relative to historical rates. Model results also demonstrate how small-scale, episodic cliff failure events can coalesce through time into spatially uniform, long-term cliff retreat signals.

  7. Knickpoint Retreat: the Role of Channel Self-Organisation

    NASA Astrophysics Data System (ADS)

    Baynes, E.; Lague, D.; Attal, M.

    2016-12-01

    Landscape connectivity occurs through the valley network, and the action of rivers within these valleys controls both landscape morphology, and landscape response to tectonic or climatic change. Such response to transient forcing is manifested in bedrock river profiles through migrating `knickzones' or `knickpoints', that separate a downstream reach, broadly in equilibrium with the new conditions and an upstream reach which is yet to adjust. Knickpoints therefore mark a dynamic boundary location within mountain landscapes, yet the complexities of the mechanisms of knickpoint retreat are often ignored in studies of landscape evolution. We carried out a series of box flume experiments (65 cm long, 30 cm wide), to explore the importance of mean discharge and substrate strength on the form and migration of knickpoints in a cohesive homogenous substrate. The retreat rate of knickpoints is independent of mean discharge, with knickpoints retreating faster through a weaker substrate. Despite an order of magnitude increase in discharge during our experiments, the bed shear stress remains almost constant due to a self-regulatory response of channel width to higher discharge, leading to no change in the upstream retreat rate of the waterfalls. These experiments challenge the established assumption in models of landscape evolution that a simple relationship exists between knickpoint retreat and discharge/drainage area, and we hypothesise that the correlation between knickpoint retreat and drainage area identified in some landscapes is caused by increasing bedload flux (the `tools' for erosion) with drainage area. Knickpoint retreat modelling approaches should therefore be re-evaluated, and greater attention paid to the role of bedload flux and connectivity between river channels and hillslopes.

  8. The Time It Takes: A Longitudinal Study of the 2003 Cohort Eligible to Transfer to a Research Intensive University. Research Results

    ERIC Educational Resources Information Center

    Lavin, Tracy

    2011-01-01

    For a number of years, the Student Transitions Project (STP) has tracked the students in BC's public colleges, institutes and teaching intensive universities (CDW institutions) who are eligible to transfer (ETR) to any of the four research intensive universities in BC in the subsequent year (i.e., students who have completed or enrolled in at…

  9. The Relationship between Intensity and Breadth of After-School Program Participation and Academic Achievement: Evidence from a Short-Term Longitudinal Study

    ERIC Educational Resources Information Center

    Springer, Ken; Diffily, Deborah

    2012-01-01

    We explored the extent to which intensity and breadth of participation in an after-school program (ASP) predicted academic achievement, as measured by changes in grades and attendance. The sample comprised 719 2nd-grade through 8th-grade Boys and Girls Clubs of Greater Dallas members during the 2009-2010 academic year. With respect to intensity,…

  10. The Time It Takes: A Longitudinal Study of the 2003 Cohort of Students Eligible to Transfer to a BC Research Intensive University

    ERIC Educational Resources Information Center

    Lavin, Tracy

    2011-01-01

    The BC Transfer System allows students to attend public colleges, institutes and teaching intensive universities (i.e., Central Data Warehouse or CDW reporting institutions) throughout the province where they accumulate credits which they can transfer to research intensive universities and use to fulfill their degree requirements. The Student…

  11. The Relationship between Intensity and Breadth of After-School Program Participation and Academic Achievement: Evidence from a Short-Term Longitudinal Study

    ERIC Educational Resources Information Center

    Springer, Ken; Diffily, Deborah

    2012-01-01

    We explored the extent to which intensity and breadth of participation in an after-school program (ASP) predicted academic achievement, as measured by changes in grades and attendance. The sample comprised 719 2nd-grade through 8th-grade Boys and Girls Clubs of Greater Dallas members during the 2009-2010 academic year. With respect to intensity,…

  12. Endodontic retreatment in case of failure. Case report.

    PubMed

    Mărgărit, Ruxandra; Andrei, Oana Celia

    2011-01-01

    In medical practice, clinicians come across an increased number of endodontic treatments, which, like other dental treatments, can fail. The increase in the number of endodontic treatment resulted in an increased number of failures, their management raising complex and serious endodontic problems. The endodontic retreatment of a failure is required by the increased desire to preserve the tooth on the dental arch, thus preventing the need for dental extraction that may have adverse consequences in terms of functional and psychological effect on patients. This article presents two clinical cases that required endodontic retreatment in order to avoid the complications that could ultimately require tooth extraction. The teeth in question (a mandibular first molar and an upper central incisor) having a special importance, and a physiognomic role, the endodontic retreatment consisted in covering them in porcelain fused to the metal crowns.

  13. Unprecedented springtime retreat of Antarctic sea ice in 2016

    NASA Astrophysics Data System (ADS)

    Turner, John; Phillips, Tony; Marshall, Gareth J.; Hosking, J. Scott; Pope, James O.; Bracegirdle, Thomas J.; Deb, Pranab

    2017-07-01

    During austral spring 2016 Antarctic sea ice extent (SIE) decreased at a record rate of 75 × 103 km2 d-1, which was 46% faster than the mean rate and 18% faster than in any previous spring season during the satellite era. The decrease of sea ice area was also exceptional and 28% greater than the mean. Anomalous negative retreat occurred in all sectors of the Antarctic but was greatest in the Weddell and Ross Seas. Record negative SIE anomalies for the day of year were recorded from 3 November 2016 to 9 April 2017. Rapid ice retreat in the Weddell Sea took place in strong northerly flow after an early maximum ice extent in late August. Rapid ice retreat occurred in November in the Ross Sea when surface pressure was at a record high level, with the Southern Annular Mode at its most negative for that month since 1968.

  14. Ocean forcing of glacier retreat in the western Antarctic Peninsula.

    PubMed

    Cook, A J; Holland, P R; Meredith, M P; Murray, T; Luckman, A; Vaughan, D G

    2016-07-15

    In recent decades, hundreds of glaciers draining the Antarctic Peninsula (63° to 70°S) have undergone systematic and progressive change. These changes are widely attributed to rapid increases in regional surface air temperature, but it is now clear that this cannot be the sole driver. Here, we identify a strong correspondence between mid-depth ocean temperatures and glacier-front changes along the ~1000-kilometer western coastline. In the south, glaciers that terminate in warm Circumpolar Deep Water have undergone considerable retreat, whereas those in the far northwest, which terminate in cooler waters, have not. Furthermore, a mid-ocean warming since the 1990s in the south is coincident with widespread acceleration of glacier retreat. We conclude that changes in ocean-induced melting are the primary cause of retreat for glaciers in this region.

  15. Comparison of the amount of apical debris extrusion associated with different retreatment systems and supplementary file application during retreatment process.

    PubMed

    Çiçek, Ersan; Koçak, Mustafa Murat; Koçak, Sibel; Sağlam, Baran Can

    2016-01-01

    The type of instrument affects the amount of debris extruded. The aim of this study was to compare the effect of retreatment systems and supplementary file application on the amount of apical debris extrusion. Forty-eight extracted mandibular premolars with a single canal and similar length were selected. The root canals were prepared with the ProTaper Universal system with a torque-controlled engine. The root canals were dried and were obturated using Gutta-percha and sealer. The specimens were randomly divided into four equal groups according to the retreatment procedures (Group 1, Mtwo retreatment files; Group 2, Mtwo retreatment files + Mtwo rotary file #30 supplementary file; Group 3, ProTaper Universal retreatment (PTUR) files; and Group 4, PTUR files + ProTaper F3 supplementary file). The extruded debris during instrumentation were collected into preweighed Eppendorf tubes. The amount of apically extruded debris was calculated by subtracting the initial weight of the tube from the final weight. Three consecutive weights were obtained for each tube. No statistically significant difference was found in the amount of apically extruded debris between Groups 1 and 3 (P = 0.590). A significant difference was observed between Groups 1 and 2 (P < 0.05), and between Groups 3 and 4 (P < 0.05). The use of supplementary file significantly increased the amount of apically extruded debris.

  16. Comparison of the amount of apical debris extrusion associated with different retreatment systems and supplementary file application during retreatment process

    PubMed Central

    Çiçek, Ersan; Koçak, Mustafa Murat; Koçak, Sibel; Sağlam, Baran Can

    2016-01-01

    Background: The type of instrument affects the amount of debris extruded. The aim of this study was to compare the effect of retreatment systems and supplementary file application on the amount of apical debris extrusion. Materials and Methods: Forty-eight extracted mandibular premolars with a single canal and similar length were selected. The root canals were prepared with the ProTaper Universal system with a torque-controlled engine. The root canals were dried and were obturated using Gutta-percha and sealer. The specimens were randomly divided into four equal groups according to the retreatment procedures (Group 1, Mtwo retreatment files; Group 2, Mtwo retreatment files + Mtwo rotary file #30 supplementary file; Group 3, ProTaper Universal retreatment (PTUR) files; and Group 4, PTUR files + ProTaper F3 supplementary file). The extruded debris during instrumentation were collected into preweighed Eppendorf tubes. The amount of apically extruded debris was calculated by subtracting the initial weight of the tube from the final weight. Three consecutive weights were obtained for each tube. Results: No statistically significant difference was found in the amount of apically extruded debris between Groups 1 and 3 (P = 0.590). A significant difference was observed between Groups 1 and 2 (P < 0.05), and between Groups 3 and 4 (P < 0.05). Conclusions: The use of supplementary file significantly increased the amount of apically extruded debris. PMID:27563185

  17. Managed Retreat: A Global Analysis of Drivers, Barriers, and Outcomes

    NASA Astrophysics Data System (ADS)

    Hino, M.; Mach, K. J.; Field, C. B.

    2016-12-01

    Managed retreat is the strategic relocation of structures or abandonment of land to reduce natural hazard risk. Although managed retreat is a potentially important climate change adaptation option, it has not yet been deployed or studied as extensively as traditional protection or accommodation measures such as levees and beach nourishment. Its application faces numerous social and legal challenges that complicate its integration into a risk-management portfolio. However, a deeper understanding of its potential future use is urgently needed given the projected scope of climate-induced displacement in the coming decades. We evaluate the drivers, barriers, and outcomes of 27 recent cases of managed retreat that have resettled 1.6-2.7 million people. The examples originate in 19 countries, occur in pre- and post-disaster settings, and address flooding, erosion, earthquakes, and tsunamis. A model based on two key factors—who benefits from retreat and who initiates it—organizes the diverse set of cases into four quadrants and provides a structure for deeper analysis of case-specific complexities. Different sociopolitical features, such as the distribution of power, strength of governance, and attachment to place, emerge as particularly influential in each quadrant. The model acts as a point of departure for unpacking these complexities. By integrating these wide-ranging examples, the model enables a broader understanding of the landscape of managed retreat and the underlying social dynamics. It provides insight on how such dimensions can be incorporated into decision-making in a changing climate, advancing consideration and potential implementation of retreat.

  18. Is rate of glacial retreat accelerated in Indian Himalaya? (Invited)

    NASA Astrophysics Data System (ADS)

    Kulkarni, A. V.

    2013-12-01

    The Himalaya has one of the largest concentration of glaciers and rivers like Indus, Ganga and Bramhputra originate from this region. The snow and glacier melt is an important source of water for these rivers. However, this source of water may get affected in the near future due to changes in the cryosphere. Therefore, retreat of Himalayan glaciers are discussed extensively in scientific and public forums in India. Conventionally health of glaciers is assessed using changes in glacial length, as it is widely measured. However changes in glacial length and loss in areal extent near terminus needs to be interpreted carefully, as these changes can be influenced by numerous terrain and climatically sensitive parameters. The terrain parameters which can influence glacial retreat are slope, area altitude distribution, debris cover and orientation. In addition, climatically sensitive parameters like mass balance, glacial lakes and black carbon can also influence glacier retreat. These multiple influences can produce a complex pattern of glacial retreat. In this paper long-term glacier retreat in three river basins in the Indian Himalaya as Tista, Baspa and Parbati will be discussed. These basins are located in different climatically sensitive regions and each basin has unique dominant process of mass wasting. In addition to terrain parameters, influence of process like formation and expansion of moraine dammed lakes in Tista basin, deposition of black carbon on accumulation area in Baspa basin and debris cover in Parbati basin will also be discussed. This will provide understanding on varying influence of different mass wasting processes on glacial retreat during last five decades in the Indian Himalaya.

  19. From Source to Confluence - Complex Patterns in Suspended Sediment Transport Revealed by a Dense Longitudinal Array of 13 Sensors Along an Intensively-Managed Stream in SE Idaho

    NASA Astrophysics Data System (ADS)

    Guilinger, J. J.; Crosby, B. T.

    2016-12-01

    Suspended sediment plays a vital role in aquatic ecosystems - acting as a primary vector for the delivery of nutrients. However, persistently high suspended sediment and associated high turbidity are detrimental to fish and benthic habitat. Identifying the sources and fate of suspended sediment is a major challenge in managed watersheds around the world. Though high frequency measurements of water quality are becoming more common, they are typically made at only one station. In order to identify distributed suspended sediment sources and track the transmission of that sediment, we deployed a dense longitudinal array of 13 water quality sondes and water level loggers along 80 km of Marsh Creek, an agriculturally-modified and impaired channel in SE Idaho. Initial suspended sediment load estimates during the high-flow period of early 2016 confirm the anticipated downstream-progressive increases in flux (eight-fold increase between upper basin and outlet). Though sediment flux increases, the concentration remains relatively consistent along the mainstem. As flows wane in the early summer, overall loads decrease but surprisingly, the longitudinal continuity of sediment flux becomes complicated. Sediment concentrations are inconsistent in the downstream direction. An impulse of sediment passing one station is often not observed at the next site downstream. Upstream sites are found to convey more sediment than some downstream stations. This implies that as flows recede and the system becomes transport-limited in the summer, sediment is retained at various sites between the upper and the lower basin. During subsequent high flows, the trapped sediment is remobilized and is transported out of the basin. This has important implications for decisions of sampling frequency, sensor placement and the accurate estimation of sediment loads. We evaluate these longitudinal and temporal patterns in sediment transport and storage relative to along-stream variation in channel slope

  20. Quantifying global warming from the retreat of glaciers

    SciTech Connect

    Oerlemans, J. )

    1994-04-08

    Records of glacier fluctuations compiled by the World Glacier Monitoring Service can be used to derive an independent estimate of global warming during the last 100 years. Records of different glaciers are made comparable by a two-step scaling procedure; one allowing for differences in glacier geometry, the other for differences in climate sensitivity. The retreat of glaciers during the last 100 years appears to be coherent over the globe. On the basis of modeling of the climate sensitivity of glaciers, the observed glacier retreat can be explained by a linear warming trend of 0.66 kelvin per century.

  1. Quantifying global warming from the retreat of glaciers.

    PubMed

    Oerlemans, J

    1994-04-08

    Records of glacier fluctuations compiled by the World Glacier Monitoring Service can be used to derive an independent estimate of global warming during the last 100 years. Records of different glaciers are made comparable by a two-step scaling procedure: one allowing for differences in glacier geometry, the other for differences in climate sensitivity. The retreat of glaciers during the last 100 years appears to be coherent over the globe. On the basis of modeling of the climate sensitivity of glaciers, the observed glacier retreat can be explained by a linear warming trend of 0.66 kelvin per century.

  2. The Social Justice Leadership Retreat: A Phenomenological Case Study of Students' Construction of Race and Its Influence on Beliefs, Behavior, and Actions

    ERIC Educational Resources Information Center

    Bettendorf, Anthony J.

    2016-01-01

    This study examines students' participation in an intensive intercultural experience, the Social Justice Leadership Retreat. The study utilizes the Intercultural Maturity Model, leadership and democracy outcomes as a framework for the research. Specifically, the study investigates how this experience impacts the ways students make meaning of…

  3. The Social Justice Leadership Retreat: A Phenomenological Case Study of Students' Construction of Race and Its Influence on Beliefs, Behavior, and Actions

    ERIC Educational Resources Information Center

    Bettendorf, Anthony J.

    2016-01-01

    This study examines students' participation in an intensive intercultural experience, the Social Justice Leadership Retreat. The study utilizes the Intercultural Maturity Model, leadership and democracy outcomes as a framework for the research. Specifically, the study investigates how this experience impacts the ways students make meaning of…

  4. Ultrastructural examination of failed molar retreatment with secondary apical periodontitis: an examination of endodontic biofilms in an endodontic retreatment failure.

    PubMed

    Carr, Gary B; Schwartz, Richard S; Schaudinn, Christoph; Gorur, Amita; Costerton, J William

    2009-09-01

    A light and electron microscope examination of the resected root tip of a failing endodontically re-treated lower molar was examined. The tooth had been initially treated 10 years ago and then re-treated 2 years ago. The resected root tip was sectioned axially, and thin sections were examined through the entire length of the specimen. Thin sections were examined with a transmission electron microscope. The thin sections were randomly chosen along the isthmus areas between the mesiobuccal and mesiolingual canals. Our findings suggest that a complex, variable, multispecies biofilm was present the entire length of the specimen.

  5. Effects of errors in velocity tilt on maximum longitudinal compression during neutralized drift compression of intense beam pulses: I. general description

    SciTech Connect

    Kaganovich, Igor D.; Massidda, Scottt; Startsev, Edward A.; Davidson, Ronald C.; Vay, Jean-Luc; Friedman, Alex

    2012-06-21

    Neutralized drift compression offers an effective means for particle beam pulse compression and current amplification. In neutralized drift compression, a linear longitudinal velocity tilt (head-to-tail gradient) is applied to the non-relativistic beam pulse, so that the beam pulse compresses as it drifts in the focusing section. The beam current can increase by more than a factor of 100 in the longitudinal direction. We have performed an analytical study of how errors in the velocity tilt acquired by the beam in the induction bunching module limit the maximum longitudinal compression. It is found that the compression ratio is determined by the relative errors in the velocity tilt. That is, one-percent errors may limit the compression to a factor of one hundred. However, a part of the beam pulse where the errors are small may compress to much higher values, which are determined by the initial thermal spread of the beam pulse. It is also shown that sharp jumps in the compressed current density profile can be produced due to overlaying of different parts of the pulse near the focal plane. Examples of slowly varying and rapidly varying errors compared to the beam pulse duration are studied. For beam velocity errors given by a cubic function, the compression ratio can be described analytically. In this limit, a significant portion of the beam pulse is located in the broad wings of the pulse and is poorly compressed. The central part of the compressed pulse is determined by the thermal spread. The scaling law for maximum compression ratio is derived. In addition to a smooth variation in the velocity tilt, fast-changing errors during the pulse may appear in the induction bunching module if the voltage pulse is formed by several pulsed elements. Different parts of the pulse compress nearly simultaneously at the target and the compressed profile may have many peaks. The maximum compression is a function of both thermal spread and the velocity errors. The effects of the

  6. Scientists Discover New Possibilities at Scientific Investigators Retreat | Poster

    Cancer.gov

    By Nancy Parrish, Staff Writer; photos by Richard Frederickson, Staff Photographer Scientists who attended the 2015 NCI Intramural Scientific Investigators Retreat on Jan. 13 had a chance to discuss research results with other investigators from across the National Cancer Institute. And this year, they could also explore new possibilities for the future of their research.

  7. Partner Choice and the Differential Retreat from Marriage

    ERIC Educational Resources Information Center

    Schoen, Robert; Cheng, Yen-Hsin Alice

    2006-01-01

    The contemporary retreat from marriage in the United States has had a differential impact across socioeconomic and racial groups. Here, 1990 marriage rates and propensities for Virginia, North Carolina, and Wisconsin are analyzed regarding (a) the likelihood that persons in different groups ever marry and (b) patterns of partner choice with…

  8. Jumpstarting Junior Faculty Motivation and Performance with Focused Writing Retreats

    ERIC Educational Resources Information Center

    Girardeau, Laura; Rud, A. G.; Trevisan, Michael S.

    2014-01-01

    Faculty members are critical assets to universities, and large losses to institutions occur if they are not successful. Although institutions value publications and grants in the tenure process, newer professors receive little guidance in writing for these endeavors. Faculty writing retreats help apprentice professors in the craft of writing;…

  9. Scientists Discover New Possibilities at Scientific Investigators Retreat | Poster

    Cancer.gov

    By Nancy Parrish, Staff Writer; photos by Richard Frederickson, Staff Photographer Scientists who attended the 2015 NCI Intramural Scientific Investigators Retreat on Jan. 13 had a chance to discuss research results with other investigators from across the National Cancer Institute. And this year, they could also explore new possibilities for the future of their research.

  10. Dendrogeomorphic approach to estimating slope retreat, Maxey Flats, Kentucky

    NASA Astrophysics Data System (ADS)

    Hupp, Cliff R.; Carey, William P.

    1990-07-01

    A dendrogeomorphic study of slope retreat was conducted at the Maxey Flats nuclear-waste disposal site in northeastern Kentucky. Tree roots exposed by surface lowering were used as an indicator of ground surface at the time of germination. The amount of lowering was measured and divided by tree-ring-determined tree age. Surface lowering and slope degradation rates were estimated for three slopes below waste-burial trenches and compared with data obtained from sediment troughs and erosion frames at the site. Mean rates of slope retreat ranged from 1.92 to 3.16 mm/yr. Sediment-trough results are two to three orders of magnitude less than dendrogeomorphic and erosion-frame estimates of slope degradation, which suggests that piping and solution-weathering processes may be important in slope degradation. Slope aspect and declivity may be important factors affecting retreat of slopes with a uniform lithology. Dendrogeomorphic techniques provide results comparable to those in the literature and offer a rapid method for estimating slope retreat that integrates slope processes over many years.

  11. Rates of scarp retreat: A means of dating Neotectonic activity

    NASA Astrophysics Data System (ADS)

    Schmidt, Karl-Heinz

    Tectonically induced scraps have attracted much geomorphic and geologic interest in recent years. The distance of a cuesta scarp from a fault line or a domal structure is an age indicator of tectonic movements, if information on the rate of scarp retreat can be obtained. In Southern Morocco rates of retreat were determined by using the information given (1) by dated volcanic or sedimentary material in the foreland of scarps, (2) by gravels that were deposited on the cuesta backslope before the formation of the scarp, and (3) especially by talus relics or sequences of talus relics in the foreland of scarps. The methods were applied to a number of different cuesta scarps in Mio-Pliocene conglomerates, in Paleogene and Cretaceous limestones. The rates of retreat avarage 1,3 km/Mio. years for the thin conglomeratic caprocks, and 0,5 km/Mio. years for the more resistant and thicker limestone caprocks. Sequences of talus relics proved to be most valuable for determining rates of retreat, because the talus and pediment flatirons represent former scarp slope positions. As caprock lithology does not differ very much in the area under investigation the recession rates calculated so far yield a reliable basis for estimating the time of activation of scarps in geodynamically relevant positions. The transition from depositional environments to subaerial erosion in the Pre-Saharan depression happened much earlier between Goulmima and Errachidia (Middle Tertiary) than in the western part (Late Miocene to Early Pliocene).

  12. Exploring the Effectiveness of a Retreat Method for Extension Staff

    ERIC Educational Resources Information Center

    Worker, Steven M.; Hill, Russell D.; Miller, JoLynn C.; Go, Charles G.; Boyes, Rita J.

    2015-01-01

    The California 4-H Association hosted two retreats to support its members with goals of balancing professional development with intentional relationship building. Evaluations demonstrated that staff found the intentional balance of time spent in unstructured, semi-structured, and structured time offered opportunities to grow professionally while…

  13. Jumpstarting Junior Faculty Motivation and Performance with Focused Writing Retreats

    ERIC Educational Resources Information Center

    Girardeau, Laura; Rud, A. G.; Trevisan, Michael S.

    2014-01-01

    Faculty members are critical assets to universities, and large losses to institutions occur if they are not successful. Although institutions value publications and grants in the tenure process, newer professors receive little guidance in writing for these endeavors. Faculty writing retreats help apprentice professors in the craft of writing;…

  14. Promoting Writing for Research: The "Writing Retreat" Model

    ERIC Educational Resources Information Center

    Singh, R. J.

    2012-01-01

    Research papers take a long time to write and in an academic environment where the "publish or perish" clause applies, writing retreats are a way of creating time and space to write academic articles in a concentrated period of time. This article examines ways in which academics can write more articles for publication. In particular it…

  15. Exploring the Effectiveness of a Retreat Method for Extension Staff

    ERIC Educational Resources Information Center

    Worker, Steven M.; Hill, Russell D.; Miller, JoLynn C.; Go, Charles G.; Boyes, Rita J.

    2015-01-01

    The California 4-H Association hosted two retreats to support its members with goals of balancing professional development with intentional relationship building. Evaluations demonstrated that staff found the intentional balance of time spent in unstructured, semi-structured, and structured time offered opportunities to grow professionally while…

  16. Healing of apical periodontitis through modern endodontic retreatment techniques.

    PubMed

    Ray, Jarom J; Kirkpatrick, Timothy C

    2013-01-01

    The presence of apical periodontitis in teeth which have undergone initial root canal treatment is largely attributed to bacteria residing in or invading from the apical root canal space. Bacteria-associated apical periodontitis will not heal spontaneously, nor will systemic antibiotics eradicate the infection. Only endodontic retreatment, endodontic surgery, or extraction will control the bacterial etiology. Modern retreatment is an effective means of addressing apical periodontitis. A mandibular premolar with apical periodontitis, apical root resorption, and overfilled gutta percha was retreated with post removal, retrieval of gutta percha from beyond the apex, ultrasonic irrigation and disinfection, and placement of a collagen internal matrix to facilitate a well-controlled MTA apical fill. The magnification and illumination imparted by the operating microscope was integral to achievement of treatment objectives. The patient's symptoms were resolved and complete osseous healing occurred. During treatment planning, clinicians should consider the capability of modern endodontic techniques to overcome technical challenges, often allowing the natural dentition to be preserved and restored to function days after retreatment.

  17. Spiral computed tomography assessment of the efficacy of different rotary versus hand retreatment system

    PubMed Central

    Mittal, Neelam; Jain, Jyoti

    2014-01-01

    Aims: The purpose of this study was to evaluate the efficacy of nickel-titanium rotary retreatment systems versus stainless steel hand retreatment system with or without solvent for gutta-percha removal during retreatment. Materials and Methods: Sixty extracted human mandibular molar teeth with single canal in a distal root was prepared with ProTaper rotary nickel-titanium files and obturated with gutta-percha and sealer. The teeth were randomly divided into six groups of 10 specimens in each groups. The volume of filling material before and after retreatment were evaluated in cm3 using the computed tomography (CT) scanner proprietary software. Results: Maximum amount of filling material removed during retreatment with ProTaper retreatment system with solvent and minimum with hand retreatment system with solvent. Conclusions: None of the technique was 100% effective in removing the filling materials, but the ProTaper retreatment system with solvent was better. PMID:24554852

  18. A century of ice retreat on Kilimanjaro: the mapping reloaded

    NASA Astrophysics Data System (ADS)

    Cullen, N. J.; Sirguey, P.; Mölg, T.; Kaser, G.; Winkler, M.; Fitzsimons, S. J.

    2013-03-01

    A new and consistent time series of glacier retreat on Kilimanjaro over the last century has been established by re-interpreting two historical maps and processing nine satellite images, which removes uncertainty about the location and extent of past and present ice bodies. Three-dimensional visualization techniques were used in conjunction with aerial and ground-based photography to facilitate the interpretation of ice boundaries over eight epochs between 1912 and 2011. The glaciers have retreated from their former extent of 11.40 km2 in 1912 to 1.76 km2 in 2011, which represents a total loss of about 85% of the ice cover over the last 100 yr. The total loss of ice cover is in broad agreement with previous estimates, but to further characterize the spatial and temporal variability of glacier retreat a cluster analysis using topographical information (elevation, slope and aspect) was performed to segment the ice cover as observed in 1912, which resulted in three glacier zones being identified. Linear extrapolation of the retreat in each of the three identified glacier assemblages implies the ice cover on the western slopes of Kilimanjaro will be gone before 2020, while the remaining ice bodies on the plateau and southern slopes will most likely disappear by 2040. It is highly unlikely that any body of ice will be present on Kilimanjaro after 2060 if present-day climatological conditions are maintained. Importantly, the geo-statistical approach developed in this study provides us with an additional tool to characterize the physical processes governing glacier retreat on Kilimanjaro. It remains clear that, to use glacier response to unravel past climatic conditions on Kilimanjaro, the transition from growth to decay of the plateau glaciers must be further resolved, in particular the mechanisms responsible for vertical cliff development.

  19. A century of ice retreat on Kilimanjaro: the mapping reloaded

    NASA Astrophysics Data System (ADS)

    Cullen, N. J.; Sirguey, P.; Mölg, T.; Kaser, G.; Winkler, M.; Fitzsimons, S. J.

    2012-10-01

    A new and consistent time series of glacier retreat on Kilimanjaro over the last century has been established by re-interpreting two historical maps and processing nine satellite images, which removes uncertainty about the location and extent of past and present ice bodies. Three-dimensional visualization techniques were used in conjunction with aerial and ground-based photography to facilitate the interpretation of ice boundaries over eight epochs between 1912 and 2011. The glaciers have retreated from their former extent of 11.40 km2 in 1912 to 1.76 km2 in 2011, which represents a total loss of about 85% of the ice cover over the last 100 yr. The total loss of ice cover is in broad agreement with previous estimates but to further characterize the spatial and temporal variability of glacier retreat a cluster analysis using topographical information (elevation, slope and aspect) was performed to segment the ice cover as observed in 1912, which resulted in three glacier zones being identified. Linear extrapolation of the retreat in each of the three identified glacier assemblages imply the ice cover on the western slopes of Kilimanjaro will be gone before 2020, while the remaining ice bodies on the plateau and southern slopes will most likely disappear by 2040. It is highly unlikely that any body of ice will be present on Kilimanjaro after 2060 if present-day climatological conditions are maintained. Importantly, the geo-statistical approach developed in this study provides us with an additional tool to characterize the physical processes governing glacier retreat on Kilimanjaro. It remains clear that to use glacier response to unravel past climatic conditions on Kilimanjaro the transition from growth to decay of the plateau glaciers must be further resolved, in particular the mechanisms responsible for vertical cliff development.

  20. Outcomes of nonsurgical retreatment and endodontic surgery: a systematic review.

    PubMed

    Torabinejad, Mahmoud; Corr, Robert; Handysides, Robert; Shabahang, Shahrokh

    2009-07-01

    The purpose of this systematic review was to compare the clinical and radiographic outcomes of nonsurgical retreatment with those of endodontic surgery to determine which modality offers more favorable outcomes. The study began with targeted electronic searches of MEDLINE, PubMed, and Cochrane databases, followed with exhaustive hand searching and citation mining for all articles reporting clinical and/or radiographic outcomes for at least a mean follow-up of 2 years for these procedures. Pooled and weighted success rates were determined from a meta-analysis of the data abstracted from the articles. A significantly higher success rate was found for endodontic surgery at 2-4 years (77.8%) compared with nonsurgical retreatment for the same follow-up period (70.9%; P < .05). At 4-6 years, however, this relationship was reversed, with nonsurgical retreatment showing a higher success rate of 83.0% compared with 71.8% for endodontic surgery (P < .05). Insufficient numbers of articles were available to make comparisons after 6 years of follow-up period. Endodontic surgery studies showed a statistically significant decrease in success with each increasing follow-up interval (P < .05). The weighted success for 2-4 years was 77.8%, which declined at 4-6 years to 71.8% and further declined at 6+ years to 62.9% (P < .05). Conversely, the nonsurgical retreatment success rates demonstrated a statistically significant increase in weighted success from 2-4 years (70.9%) to 4-6 years (83.0%; P < .05). On the basis of these results it appears that endodontic surgery offers more favorable initial success, but nonsurgical retreatment offers a more favorable long-term outcome.

  1. Attack or retreat: contrasted defensive tactics used by Cyprian honeybee colonies under attack from hornets.

    PubMed

    Papachristoforou, Alexandros; Rortais, Agnès; Sueur, Jérôme; Arnold, Gérard

    2011-02-01

    This study describes the tactics used by Cyprian honeybees (Apis mellifera cypria) to defend their colonies against hornet (Vespa orientalis orientalis) attacks. We use simulated hornet attacks and a combination of video recordings and image analysis to reveal, for the first time, contrasted intra-subspecies defensive tactics that operate at the colony level during predation. In some colonies, when attacked, the numbers of guards at the hive entrance increases rapidly to attack, engulf, and kill invading hornets. In other colonies, guards avoid conflicts with hornets by retreating gradually and by forming a defensive line of honeybees at the hive entrance. Retreater colonies have propolis walls at the hive entrances with small apertures that are too narrow to allow the hornet to access the hive and that therefore reinforces entrance protection. On the contrary, attacker colonies have propolis walls with large openings through which the hornet can pass; these bees block the hornet's access by intensively guarding the hive entrance. We experimentally destroy propolis walls to test whether colonies consistently rebuild walls with the same intrinsic characteristics and we also monitor the survival rate of each anti-predator tactic after massive natural predation by hornets.

  2. Concise, intensive or longitudinal medical education courses, which is more effective in perceived self-efficacy and development of faculty members?

    PubMed Central

    Mojtahedzadeh, Rita; Mohammadi, Aeen

    2016-01-01

    Background: Teachers’ self-efficacy and development may be conceptualized as their beliefs in their own ability to plan, organize and carry out activities that are required to attain educational goals. In this study, we examined the effect of different medical education training courses (six-day, one- month short- term and sixmonth long- term courses) on perceived self-efficacy and development. Methods: This before-after quasi-experimental study was performed on 39 faculty members of Tehran University of Medical Sciences who participated in faculty development courses in 2013. We used valid and reliable scales to measure their perceived self-efficacy and empowerment. Results: The results revealed a significant increase in faculty members’ perceived self-efficacy in pre and posttests in one-month and six-month courses, but no significant difference was found in the six-day course (p=0.004, p<0.001 and p=0.235, respectively). These results were the same for perceived empowerment (p<0.001, p<0.001 and p=0.716 for one-month, six-month and six-day courses, respectively). A significant difference was detected in perceived self-efficacy and participant empowerment components based on the training course (p=0.005; Wilk's Λ=0.345, Partial η2=0.413). Conclusion: This study revealed that long- term courses were more effective than the short- term ones. Thus, longitudinal courses are recommended for more effectiveness. PMID:27683643

  3. Concise, intensive or longitudinal medical education courses, which is more effective in perceived self-efficacy and development of faculty members?

    PubMed

    Mojtahedzadeh, Rita; Mohammadi, Aeen

    2016-01-01

    Teachers' self-efficacy and development may be conceptualized as their beliefs in their own ability to plan, organize and carry out activities that are required to attain educational goals. In this study, we examined the effect of different medical education training courses (six-day, one- month short- term and sixmonth long- term courses) on perceived self-efficacy and development. This before-after quasi-experimental study was performed on 39 faculty members of Tehran University of Medical Sciences who participated in faculty development courses in 2013. We used valid and reliable scales to measure their perceived self-efficacy and empowerment. The results revealed a significant increase in faculty members' perceived self-efficacy in pre and posttests in one-month and six-month courses, but no significant difference was found in the six-day course (p=0.004, p<0.001 and p=0.235, respectively). These results were the same for perceived empowerment (p<0.001, p<0.001 and p=0.716 for one-month, six-month and six-day courses, respectively). A significant difference was detected in perceived self-efficacy and participant empowerment components based on the training course (p=0.005; Wilk's Λ=0.345, Partial η2=0.413). This study revealed that long- term courses were more effective than the short- term ones. Thus, longitudinal courses are recommended for more effectiveness.

  4. The Comparative Efficacy of Different Files in The Removal of Different Sealers in Simulated Root Canal Retreatment- An In-vitro Study

    PubMed Central

    Kanaparthy, Aruna

    2016-01-01

    Introduction Root canal treatment enjoys a high success rate all over the world and has saved billions of teeth from extraction. However, there are instances of failure, the main causes being insufficient cleaning and inadequate obturation. In such cases the most conservative treatment option would be non-surgical retreatment. It requires regaining access to the entire root canal system through removal of the original root canal filling thus permitting further cleaning and re- obturation. Removal of gutta-percha and sealer becomes a critical step to gain access to the root canal system, remove necrotic tissue debris, bacteria and infected dentin. Aim To compare and evaluate the efficacy of manual hand Hedstrom files and two rotary retreatment file systems ProTaper Universal retreatment files and MtwoR (retreatment) files in the removal of root canal filling material during root canal retreatment and the influence of the type of sealers zinc oxide eugenol and AH plus on the presence of remaining debris in the reinstrumented canals in the apical, middle and coronal third. Materials and Methods Sixty single rooted human premolar teeth were divided into 3 Groups of 20 teeth each Group I (20 Teeth): prepared using hand K Files, Group II (20 Teeth): prepared using ProTaper rotary system and Group III (20 Teeth): prepared using Mtwo rotary system. In Groups- IA, IIA, IIIA: (10 teeth each) Obturation was done using Zinc Oxide Eugenol sealer and gutta percha. In Groups- IB, IIB, IIIB: (10 teeth each) obturation was done with AH Plus sealer and gutta percha. All the teeth were subjected to retreatment. Groups IA and IB with Hedstrom files, Groups IIA and IIB with ProTaper retreatment files and for Groups IIIA and IIIB with Mtwo retreatment Files. The roots were longitudinally split and were observed under a stereomicroscope for remaining amount of filling material on the canal walls. Statistical analysis was done using One–way ANOVA (Analysis of variance) test and Tukey

  5. Motivating Parents of Kids with Asthma to Quit Smoking: The Effect of the Teachable Moment and Increasing Intervention Intensity Using a Longitudinal Randomized Trial Design

    PubMed Central

    Borrelli, Belinda; McQuaid, Elizabeth L.; Tooley, Erin M; Busch, Andrew M.; Hammond, S Katharine; Becker, Bruce; Dunsiger, Shira

    2016-01-01

    Aims We tested two aims: 1) The Teachable Moment (TM): whether second hand smoke exposure (SHSe) feedback motivates cessation in parents of children with asthma vs. parents of healthy children (HC) and 2) whether greater intervention intensity (Enhanced-PAM) produces greater cessation than a previously tested intervention (Precaution Adoption Model; PAM). Design and interventions Aim 1: Two home visits (asthma education or child wellness), and cessation induction using Motivational Interviewing and SHSe feedback. Aim 2: Post home-visits, parents with asthmatic children were randomized to PAM (n=171; 6 asthma education calls) or Enhanced-PAM (n=170; 6 asthma education/smoking cessation calls + repeat SHSe feedback). Setting Rhode Island USA. Participants Parents of asthmatic (n=341) or healthy (n=219) children who did not have to want to quit smoking to enroll. Measurements were given at baseline, 2, 4, 6 and 12 months. Abstinence was bioverified. Outcomes were 7-day and 30-day ppa, and SHSe (primary) and asthma morbidity (secondary). Findings Aim 1: The TM was supported: parents of asthmatic children were more than twice as likely to achieve 30-day (OR=2.60, 95% CI = 1.22–5.54) and 7-day ppa (OR=2.26, 95% CI=1.13–4.51) at 2 months (primary endpoint) and have non-detectable levels of SHSe than HCs. Greater treatment intensity yielded stronger TM effects (OR=3.60; 95% CI= 1.72–7.55). Aim 2: Enhanced-PAM was more likely to achieve 30-day ppa at the primary endpoint, 4-months (OR=2.12, 95% CI 1.09–4.12) and improved asthma outcomes vs. PAM. Conclusions Smoking cessation interventions (Motivational Interviewing + biomarker feedback) appear to motivate smoking cessation more strongly among parents of asthmatic children than among parents of healthy children. Increased intervention intensity yields greater smoking cessation among parents of asthmatic children and better asthma outcomes. PMID:27184343

  6. The Role of Regional Conferences in Research Resident Career Development: The California Psychiatry Research Resident Retreat.

    PubMed

    Besterman, Aaron D; Williams, Jody K; Reus, Victor I; Pato, Michele T; Voglmaier, Susan M; Mathews, Carol A

    2017-04-01

    For psychiatry research resident career development, there is a recognized need for improved cross-institutional mentoring and networking opportunities. One method to address this need is via regional conferences, open to current and recently graduated research residents and their mentors. With this in mind, we developed the biennial California Psychiatry Research Resident Retreat (CPRRR) and collected feedback from participants to 1) Assess resident satisfaction, 2) Determine the utility of the retreat as a networking and mentorship tool, and 3) Identify areas for improvement. We gathered survey data from resident attendees at the two first CPRRRs. We analyzed the data to look for trends in satisfaction as well as areas that need improvement. Thirty-two residents from five California training programs attended the CPRRR in 2013 while 33 attended from six programs in 2015. The residents were from all years of training, but concentrated in their second and third years. Approximately 41% and 49% of the attendees were female and 53% and 39% had an MD/PhD in 2013 and 2015, respectively. Twenty-four and 32 residents provided anonymous feedback in 2013 and 2015, respectively. Mean feedback scores were very high (> 4/5) for overall satisfaction, peer- and faculty-networking, the keynote speaker and the flash talks for both years. Mean feedback scores for the ethics debates and mentoring sessions were somewhat lower (≤ 4/5), however, both showed significant improvement from 2013 to 2015. The CPRRRs appear to be an effective mechanism for providing psychiatry research residents with a meaningful cross-institutional opportunity for networking and mentorship. Feedback-driven changes to the CPRRRs improved participant satisfaction for several components of the conference. Future efforts will be aimed at broadening mentorship and networking opportunities, optimizing teaching approaches for research ethics, and considering different feedback-gathering approaches to allow for

  7. Knickpoint formation and retreat: stairway to heaven or pathway to declivity

    NASA Astrophysics Data System (ADS)

    Rengers, Francis; Tucker, Gregory

    2016-04-01

    The importance of knickpoints in shaping fluvial systems has been observed in laboratory settings, small experimental plots, and at the landscape scale. By creating a step in a river's longitudinal profile, knickpoints can shield upstream tributaries from a much lower base level, and therefore represent a buffer in the energy transfer of a stream system. Knickpoints are located at a transition point between the potential energy of material stored upstream and the kinetic energy of erosion processes and sediment transport below the knickpoint. We hypothesize that the long-term persistence of a discrete, retreating knickpoint requires a balance between the fluvial erosion of the feature, and sedimentation rates downstream. Here we present the results of a short-term (four year) study of knickpoint morphology in a natural gully system to better constrain the conditions necessary to preserve distinct knickpoints over time. We monitored knickpoint erosion using time-lapse photography, repeat terrestrial lidar, soil moisture monitoring, and rainfall-runoff measurements. Our results indicate that shallow subsurface hydrology leads to knickpoint erosion via mass failure, and produces a stable and predictable morphological signature of knickpoint erosion (amphitheater shaped heads). We generalized these observations into a numerical model of erosion/sedimentation to understand the geomorphic legacy of knickpoints in deeply incised gullies. Modeling showed that knickpoints can maintain an incisional step for hundreds to thousands of years when knickpoints retreat via mass failure and sediment is removed from the knickpoint base by fluvial scour. To test simulations of long-term stability generated by the numerical model, we used Optically Stimulated Luminesence to date alluvial deposits at existing gully knickpoints. This geochronological dating confirmed that gully knickpoints have been active in our study area for hundreds to thousands of years, particularly during drought

  8. Retreating glacier fronts on the Antarctic Peninsula over the past half-century

    USGS Publications Warehouse

    Cook, A.J.; Fox, A.J.; Vaughan, D.G.; Ferrigno, J.G.

    2005-01-01

    The continued retreat of ice shelves on the Antarctic Peninsula has been widely attributed to recent atmospheric warming, but there is little published work describing changes in glacier margin positions. We present trends in 244 marine glacier fronts on the peninsula and associated islands over the past 61 years. Of these glaciers, 87% have retreated and a clear boundary between mean advance and retreat has migrated progressively southward. The pattern is broadly compatible with retreat driven by atmospheric warming, but the rapidity of the migration suggests that this may not be the sole driver of glacier retreat in this region.

  9. The 23rd Annual Prostate Cancer Foundation Scientific Retreat report.

    PubMed

    Miyahira, Andrea K; Soule, Howard R

    2017-07-01

    The 23rd Annual Prostate Cancer Foundation (PCF) Scientific Retreat was convened October 27-29, 2016, in Carlsbad, CA. This event focuses on the latest advances in basic, translational, and clinical prostate cancer research with the greatest promise for advancing our understanding of prostate cancer biology and improving patient outcomes and quality of life. Themes highlighted at this year's meeting included: i) targeting DNA repair deficiency in prostate cancer; ii) optimizing the use of Radium-223 and bone-targeting agents; iii) advances in cancer immunotherapeutic approaches; iv) targeting developmental pathways in prostate cancer; v) advances in circulating tumor DNA technology and applications; vi) precision survivorship; and vii) novel treatments and treatment strategies in prostate cancer. This article reviews the key advances discussed at the Retreat for the purpose of disseminating this knowledge to accelerate the development of new treatments and improved outcomes for men suffering with prostate cancer. © 2017 Wiley Periodicals, Inc.

  10. Effects of coastal managed retreat on mercury biogeochemistry.

    PubMed

    Sizmur, Tom; Godfrey, Adam; O'Driscoll, Nelson J

    2016-02-01

    We investigated the impact of managed retreat on mercury (Hg) biogeochemistry at a site subject to diffuse contamination with Hg. We collected sediment cores from an area of land behind a dyke one year before and one year after it was intentionally breached. These sediments were compared to those of an adjacent mudflat and a salt marsh. The concentration of total mercury (THg) in the sediment doubled after the dyke was breached due to the deposition of fresh sediment that had a smaller particle size, and higher pH. The concentration of methylmercury (MeHg) was 27% lower in the sediments after the dyke was breached. We conclude that coastal flooding during managed retreat of coastal flood defences at this site has not increased the risk of Hg methylation or bioavailability during the first year. As the sediment becomes vegetated, increased activity of Hg-methylating bacteria may accelerate Hg-methylation rate.

  11. Nonsurgical endodontic retreatment of geminated teeth: a case report.

    PubMed

    Yücel, Ali Cağin; Güler, Eda

    2006-12-01

    The purpose of this case presentation is to describe nonsurgical retreatment of anterior teeth with gemination. A 21-year-old male patient was referred for endodontic treatment of his maxillary left lateral incisor. In the clinical examination, a large crown was observed in the left maxillary incisor region when compared with the right maxillary lateral incisor. In the present case, a tooth gemination of a maxillary lateral incisor has been described. A periapical radiograph showed that the tooth had partially separated two crowns having a single root and one root canal, but the access cavity of the distal crown had not been opened, and the root canal had been obturated with single cone technique. Nonsurgical endodontic retreatment was decided for geminated lateral incisor. At the 6-month follow-up, the tooth was asymptomatic and there was no radiolucency around the apical region.

  12. Scientific Investigators Retreat Brings Like Minds Together | Poster

    Cancer.gov

    Scientists throughout NCI gathered at the 2016 Intramural Scientific Investigators Retreat on Jan. 12, at the Ronald Reagan Building and International Trade Center, to discuss the results of their research with fellow investigators. Several researchers who have made significant advances toward the goal of eliminating the threat of cancer spoke to a packed auditorium of like-minded experts. Speaker topics included the role genetics play in the risk of breast cancer, using fiberglass to...

  13. Climate Change and Glacier Retreat: Scientific Fact and Artistic Opportunity

    NASA Astrophysics Data System (ADS)

    Fagre, D. B.

    2008-12-01

    Mountain glaciers continue to retreat rapidly over most of the globe. In North America, at Glacier National Park, Montana, recent research results from Sperry Glacier (2005-2007) indicate negative mass balances are now 3-4 times greater than in the 1950s. A geospatial model of glacier retreat in the Blackfoot-Jackson basin suggested all glaciers would be gone by 2030 but has proved too conservative. Accelerated glacier shrinkage since the model was developed has mirrored an increase in actual annual temperature that is almost twice the rate used in the model. The glaciers in Glacier National Park are likely to be gone well before 2030. A variety of media, curricula, and educational strategies have been employed to communicate the disappearance of the glaciers as a consequence of global warming. These have included everything from print media and television coverage to podcasts and wayside exhibits along roads in the park. However, a new thrust is to partner with artists to communicate climate change issues to new audiences and through different channels. A scientist-artist retreat was convened to explore the tension between keeping artistic products grounded in factually-based reality while providing for freedom to express artistic creativity. Individual artists and scientists have worked to create aesthetic and emotional images, using painting, poetry, music and photography, to convey core messages from research on mountain ecosystems. Finally, a traveling art exhibit was developed to highlight the photography that systematically documents glacier change through time. The aim was to select photographs that provide the most compelling visual experience for an art-oriented viewer and also accurately reflect the research on glacier retreat. The exhibit opens on January 11, 2009

  14. Scientific Investigators Retreat Brings Like Minds Together | Poster

    Cancer.gov

    Scientists throughout NCI gathered at the 2016 Intramural Scientific Investigators Retreat on Jan. 12, at the Ronald Reagan Building and International Trade Center, to discuss the results of their research with fellow investigators. Several researchers who have made significant advances toward the goal of eliminating the threat of cancer spoke to a packed auditorium of like-minded experts. Speaker topics included the role genetics play in the risk of breast cancer, using fiberglass to...

  15. Glacial Delineation and Ice Retreat on Pico de Orizaba, Mexico

    NASA Astrophysics Data System (ADS)

    Colby, A. E.; Weissling, B.; Xie, H.

    2011-12-01

    Pico de Orizaba, a dormant stratovolcano at the eastern end of the Trans-Mexican Volcanic Belt at approximately 19 degrees of latitude and the third largest peak in North America (5636 m), hosts what is likely the last significant tropical zone glacier (Jamapa Glacier) in the Northern Hemisphere. Not since the International Geophysical Year of 1957-58 has Pico's glacial environment been studied with any focused effort, perhaps due to the general innaccessibility, high altitude, and steep slopes. As are most glaciers around the world, the Jamapa Glacier is retreating, with a remarkable loss of ice in the past 2 decades. The rate and pattern of retreat is important to understanding climate change forcing as well as understanding environmental and water supply impacts to a substantial human population who live along the base of the volcano. Through the use of satellite imagery (LandSat, ASTER, IKONOS), legacy hand-drawn maps, aerial photographs, and first-hand accounts from climber's expeditions, a reasonably accurate map of almost 60 years of glacial retreat has been produced. Legacy hand-drawn maps of the ice edge, that pre-date the satellite era, did not fit perfectly with modern images when layered in ArcGIS. Oblique perspectives in Google Earth and various aerial and surface-based photographs of the mountain were used to help fit the ice edge to the actual topography. The disparity of satellite image pixel resolution (from 1 m IKONOS to 60 m LandSat) was addressed using various imagery analysis tools (eg. edge detection convolution filters and pixel unmixing) in order to delineate an approximate ice edge for the respective image date. The final map shows the nature of ice edge retreat on Pico de Orizaba from 1945 up until the present (Feb 2011).

  16. [Re-treatments of recurrence after pelvic floor repair surgery].

    PubMed

    Fan, S X; Wang, F M; Lin, L S; Song, Y F

    2017-06-25

    Objective: To analyze re-treatments of recurrence after the pelvic floor repair surgery. Methods: The protocol and the effect of re-treatments were investigated by reviewing and analyzing the clinical data of 81 recurrent patients (grade Ⅱ and above), who had received the pelvic floor repair surgery from January 2011 to January 2016. Pelvic organ prolapse quantitation system (POP-Q) and two questionnaires about quality of life [pelvic floor distress inventory-short form 20 (PFDI-20) and pelvic floor impact questionnaire short form (PFIQ-7)] were used to evaluate objective and subjective efficacy, respectively. Results: Among 81 recurrent patients who were followed up for a median of 35 months (10- 69 months), 78 cases (with prolapse up to grade Ⅲ or Ⅳ) were treated by surgical operation with both objective cure rate and subjective satisfaction being 100% (78/78); 3 cases (with grade Ⅱ prolapse) were treated by pelvic floor electrical stimulation biofeedback, and 1 case among the three cases had the vaginal foreign body sensation, the subjective satisfaction was 2/3. The methods of surgical operation for the 78 recurrent patients included: total pelvic floor reconstructive surgery (55 cases; 3 of which involve trachelectomy), anterior pelvic reconstructive surgery (2 cases), posterior pelvic reconstructive surgery (3 cases), Y-mesh sacral colpopexy (2 cases), colpocleisis (11 cases), vaginal hysterectomy combined posterior fornix forming (3 cases), and vaginal hysterectomy combined posterior pelvic reconstructive surgery(2 cases). Conclusion: The extent of recurrence, the recurrent site and complications must be carefully considered and evaluated for re-treatments of recurrence after pelvic floor repair surgery, and then an appropriately individualized re-treatment protocol could be designed for each of the patients.

  17. 3-Year follow-up after Lasik: assessing the risk factors for retreatment.

    PubMed

    Valdez-García, Jorge E; Hernandez-Camarena, Julio C; Martínez-Muñoz, Rosa

    2016-02-01

    The purpose of this study was to evaluate the correlation of important risk factors for LASIK retreatment and the retreatment rate. A retrospective cohort study was conducted. Records of patients who underwent LASIK between January 2011 and January 2012 at the Zambrano-Hellion Medical Center, Tec de Monterrey (México), and posteriorly underwent LASIK retreatment were identified and risk factors to receive retreatment were assessed using relative risk. Main outcomes were retreatment rate, risk factors for retreatment, and uncorrected distance visual acuity (UDVA). 482 eyes from 241 patients were available for a 36-month follow-up analysis. 68.5 % had primary myopic LASIK; 37 % were ≤ 2 diopters (D), 52 % were > 2 and < 6 D, and 11 % were ≥ 6 D of myopia. 31.5 % of the eyes had hyperopic LASIK. Retreatment was performed in 6.85 % eyes. Myopia > 6 D (RR 4.13), hyperopic refraction (RR 3.18), and age > 40 (RR 3.07) were the most important risk factors for retreatment (P = 0.004, P = 0.007, P = 0.006, respectively). UDVA was ≥ 20/40 in 92.1 % and ≥ 20/20 in 81.6 % of the retreated eyes and 82 % of the eyes within ± 0.50 D of target refraction. Increasing degrees of myopia, followed by hyperopic refraction, and age were the most important associated factors to retreatment. LASIK retreatment was safe and effective.

  18. Retreatment Predictions in Odontology by means of CBR Systems

    PubMed Central

    Campo, Livia; Aliaga, Ignacio J.; García, Alvaro Enrique; Villarubia, Gabriel; Corchado, Juan M.

    2016-01-01

    The field of odontology requires an appropriate adjustment of treatments according to the circumstances of each patient. A follow-up treatment for a patient experiencing problems from a previous procedure such as endodontic therapy, for example, may not necessarily preclude the possibility of extraction. It is therefore necessary to investigate new solutions aimed at analyzing data and, with regard to the given values, determine whether dental retreatment is required. In this work, we present a decision support system which applies the case-based reasoning (CBR) paradigm, specifically designed to predict the practicality of performing or not performing a retreatment. Thus, the system uses previous experiences to provide new predictions, which is completely innovative in the field of odontology. The proposed prediction technique includes an innovative combination of methods that minimizes false negatives to the greatest possible extent. False negatives refer to a prediction favoring a retreatment when in fact it would be ineffective. The combination of methods is performed by applying an optimization problem to reduce incorrect classifications and takes into account different parameters, such as precision, recall, and statistical probabilities. The proposed system was tested in a real environment and the results obtained are promising. PMID:26884749

  19. Retreatment Predictions in Odontology by means of CBR Systems.

    PubMed

    Campo, Livia; Aliaga, Ignacio J; De Paz, Juan F; García, Alvaro Enrique; Bajo, Javier; Villarubia, Gabriel; Corchado, Juan M

    2016-01-01

    The field of odontology requires an appropriate adjustment of treatments according to the circumstances of each patient. A follow-up treatment for a patient experiencing problems from a previous procedure such as endodontic therapy, for example, may not necessarily preclude the possibility of extraction. It is therefore necessary to investigate new solutions aimed at analyzing data and, with regard to the given values, determine whether dental retreatment is required. In this work, we present a decision support system which applies the case-based reasoning (CBR) paradigm, specifically designed to predict the practicality of performing or not performing a retreatment. Thus, the system uses previous experiences to provide new predictions, which is completely innovative in the field of odontology. The proposed prediction technique includes an innovative combination of methods that minimizes false negatives to the greatest possible extent. False negatives refer to a prediction favoring a retreatment when in fact it would be ineffective. The combination of methods is performed by applying an optimization problem to reduce incorrect classifications and takes into account different parameters, such as precision, recall, and statistical probabilities. The proposed system was tested in a real environment and the results obtained are promising.

  20. A self-care retreat for pediatric hematology oncology nurses.

    PubMed

    Altounji, Diane; Morgan, Helene; Grover, Monica; Daldumyan, Sona; Secola, Rita

    2013-01-01

    Pediatric hematology oncology nurses face a variety of stressors while working in this specialty field. Through hematology oncology staff group discussions, nurses identified a myriad physical and emotional stressors they experienced, and expressed concern regarding possible burnout. They described facing stressors related to experiencing loss, grief, moral and ethical dilemmas, and administering complex treatment regimens. To address these concerns, a hematology oncology nursing supportive care committee envisioned and implemented 3 off-site self-care retreats. The committee's primary purpose was to create a therapeutic and supportive environment for all participants, while allowing time for relaxation, reflection, and serenity. The primary goals for the retreats were to heal nurses from their reported past trauma and stress and to provide them effective coping strategies for the ongoing stressors they will inevitably face. In a collaborative effort, the committee members developed an agenda including presentations, group discussions, and relaxation activities. Written evaluations were completed by each participant to assess the benefit of the retreat. Overall feedback was extremely positive, with the majority of the participants finding great value in this experience.

  1. Management of multidrug-resistant tuberculosis and patients in retreatment.

    PubMed

    Caminero, J A

    2005-05-01

    Retreatment of tuberculosis involves the management of entities as diverse as relapse, failure, treatment after default, and poor patient adherence to the previous treatment. The emergence of conditions for selection of resistance (failure and partial abandonment) is a matter of great concern. The development of a retreatment regimen for tuberculosis requires consideration of certain basic premises. The importance of a comprehensive and directed history of drugs taken in the past, and the limited reliability of susceptibility tests to many of these drugs, should be kept in mind. Taking this into account, and possessing a thorough knowledge of all anti-tuberculosis medications, it is possible to cure almost all patients with an appropriate retreatment regimen including a minimum of three or four drugs not previously used. Nonetheless, the treatment of these patients is so complex that it should only be carried out by experienced staff. Concern about treating tuberculosis patients with drug resistance varies greatly depending on the available resources. High-income countries should provide individual treatment regimens adapted to each patient; however, in other settings, restricted resources could justify the implementation of standardised therapeutic guidelines with second-line drugs in order to facilitate management and reduce costs.

  2. Glacier retreat since the Little Ice Age in the eastern Nyainqêntanglha Range, southeastern Tibet

    NASA Astrophysics Data System (ADS)

    Loibl, David; Grießinger, Jussi; Lehmkuhl, Frank

    2014-05-01

    The remote eastern Nyainqêntanglha Range in southeastern Tibet is situated in a transition zone between warm-wet subtropical and cold-dry plateau climate conditions. In this high mountain environment, intense summer monsoon rainfalls support numerous temperate glaciers despite the latitude of ~29° to ~31°N. Due to the outstanding importance of the monsoonal airmasses for the water cycle of the whole region, it is a key area to study climate and subsequent glacier change in High Asia. Here, we present the results of a study in which 1964 glaciers were mapped by remote sensing from a Landsat ETM+ scene and subsequently parameterized by DEM supported measurements. Geomorphological evidence, such as glacier trimlines and latero-frontal moraines, was used to delineate the Little Ice Age (LIA) maximum glacier advance terminus positions. Statistical analysis of glacier length change revealed an average retreat of ~40 % and a trend towards stronger retreat for smaller glaciers. Calculated ELAs show a southeast-northwest gradient ranging from 4,400 to 5,600 m a.s.l. and an average ELA rise of ~98 m since the LIA. Due to the large amount of measurements the ELA distribution reveals topographic effects down to the catchment scale, i.e. orographic rainfall and leeward shielding. This gives numerous hints on the relief-climate-glacier interactions and allows a simplified reconstruction of the flow patterns of the monsoonal air masses. Contrasting to the expectations for subtropical settings, glaciers on south facing slopes have not retreated strongest and ELAs on south facing slopes did not rise furthest. Instead, highly heterogeneous spatial patterns emerge that show a strong imprint of both, topography and monsoonal dynamics. Our results indicate that the monsoonal temperate glaciers' high sensitivity to climate change is driven by two double forcings due to the coincidence of accumulation and ablation phases. First, monsoon intensity directly controls the amount of

  3. On the Lateral Retreat of Salt Marshes: Field Monitoring in the Venice Lagoon (Italy)

    NASA Astrophysics Data System (ADS)

    Solari, L.; Bendoni, M.; Mel, R.; Oumeraci, H.; Francalanci, S.; Lanzoni, S.

    2014-12-01

    Salt marshes are geomorphic structures located in ecotone environments such as lagoon and estuaries, providing lot of ecosystem services to local population. In the last decades they are disappearing due to several factors such as sea level rise, subsidence and edge erosion due to surface waves. The latter is likely the chief mechanism modeling marsh boundaries and leading to the loss of wide marsh areas. In the case of the Venice Lagoon, from the beginning of the last century, the whole salt marsh surface has more than halved and trends indicate that the salt marshes might completely disappear over the next 50 years. Here, we present a field monitoring activity that we are currently carrying out on a retreating salt marsh located in the north part of the Lagoon of Venice (Italy). The marsh is subject to North-East (Bora) wind. Marsh area loss during the last decades has been documented through the comparison of georeferenced aerial photographs showing a retreat rate of the order of 1 m/year. Field measurements started by the end of November 2013 and consist of: salt marsh bank geometry at different cross-sections and wave climate in the lagoon about 30 m in front of the salt marsh. Erosion data are obtained by means of erosion pins located horizontally on the marsh scarp; at higher banks (about 0.9 m), two pins are located along the same vertical direction, for lower banks (about 0.4m), only one pin is employed. Significant wave height has been measured during three storm surges by means of pressure transducers (Pts). The measured wave climate in front of the bank was then put into relationship with the offshore wave climate estimated using wind data (intensity and direction) and bathymetric data. Wind intensity and direction is measured hourly by several measurement stations located in the Lagoon of Venice. In this way, it is possible to extrapolate wave climate hourly at the monitored marsh and calculate the wave power that acted on the bank in a given time

  4. On the Lateral Retreat of Salt Marshes: Field Monitoring in the Venice Lagoon (Italy)

    NASA Astrophysics Data System (ADS)

    Solari, L.

    2015-12-01

    Salt marshes are geomorphic structures located in ecotone environments such as lagoon and estuaries, providing lot of ecosystem services to local population. In the last decades they are disappearing due to several factors such as sea level rise, subsidence and edge erosion due to surface waves. The latter is likely the chief mechanism modeling marsh boundaries and leading to the loss of wide marsh areas. In the case of the Venice Lagoon, from the beginning of the last century, the whole salt marsh surface has more than halved and trends indicate that the salt marshes might completely disappear over the next 50 years. Here, we present a field monitoring activity on a retreating salt marsh located in the north part of the Lagoon of Venice (Italy). The marsh is subject to North-East (Bora) wind. Marsh area loss during the last decades has been documented through the comparison of georeferenced aerial photographs showing a retreat rate of the order of 1 m/year. Field measurements started by the end of November 2013 and consist of: salt marsh bank geometry at different cross-sections and wave climate in the lagoon about 30 m in front of the salt marsh. Erosion data are obtained by means of erosion pins located horizontally on the marsh scarp; at higher banks (about 0.9 m), two pins are located along the same vertical direction, for lower banks (about 0.4 m), only one pin is employed. Significant wave height has been measured during three storm surges by means of pressure transducers. The measured wave climate in front of the bank was then put into relationship with the offshore wave climate estimated using wind data (intensity and direction) and bathymetric data. Wind intensity and direction is measured hourly by several measurement stations located in the Lagoon of Venice. In this way, it is possible to extrapolate wave climate hourly at the monitored marsh and calculate the wave power that acted on the bank in a given time interval. Field survey revealed that the

  5. Dynamic changes on the Wilkins Ice Shelf during the 2006-2009 retreat derived from satellite observations

    NASA Astrophysics Data System (ADS)

    Rankl, Melanie; Fürst, Johannes Jakob; Humbert, Angelika; Holger Braun, Matthias

    2017-05-01

    The vast ice shelves around Antarctica provide significant restraint to the outflow from adjacent tributary glaciers. This important buttressing effect became apparent in the last decades, when outlet glaciers accelerated considerably after several ice shelves were lost around the Antarctic Peninsula (AP). The present study aims to assess dynamic changes on the Wilkins Ice Shelf (WIS) during different stages of ice-front retreat and partial collapse between early 2008 and 2009. The total ice-shelf area lost in these events was 2135 ± 75 km2 ( ˜ 15 % of the ice-shelf area relative to 2007). Here, we use time series of synthetic aperture radar (SAR) satellite observations (1994-1996, 2006-2010) in order to derive variations in surface-flow speed from intensity-offset tracking. Spatial patterns of horizontal strain-rate, stress and stress-flow angle distributions are determined during different ice-front retreat stages. Prior to the final break up of an ice bridge in 2008, a strong speed up is observed, which is also discernible from other derived quantities. We identify areas that are important for buttressing and areas prone to fracturing using in-flow and first principal strain rates as well as principal stress components. Further propagation of fractures can be explained as the first principal components of strain rates and stresses exceed documented threshold values. Positive second principal stresses are another scale-free indicator for ice-shelf areas, where fractures preferentially open. Second principal strain rates are found to be insensitive to ice-front retreat or fracturing. Changes in stress-flow angles highlight similar areas as the in-flow strain rates but are difficult to interpret. Our study reveals the large potential of modern SAR satellite time series to better understand dynamic and structural changes during ice-shelf retreat but also points to uncertainties introduced by the methods applied.

  6. Long-term effect of intensive lifestyle intervention on cardiovascular risk factors in patients with diabetes in real-world clinical practice: a 5-year longitudinal study

    PubMed Central

    Hamdy, Osama; Mottalib, Adham; Morsi, Amr; El-Sayed, Nuha; Goebel-Fabbri, Ann; Arathuzik, Gillian; Shahar, Jacqueline; Kirpitch, Amanda; Zrebiec, John

    2017-01-01

    Objective We evaluated long-term impact of sustained weight loss versus weight regain on cardiovascular risk factors in real-world clinical practice. Methods We evaluated 129 obese patients with diabetes enrolled in Weight Achievement and Intensive Treatment (Why WAIT) program, a 12-week clinical model of intensive lifestyle intervention. After 1 year, we divided participants into group A, who maintained <7% weight loss (47.3%) and group B (52.7%), who maintained ≥7% weight loss. We continued to follow them for a total of 5 years. Results The total cohort lost 23.8 lbs (−9.7%) at 12 weeks and maintained −16.2 lbs (−6.4%) at 5 years (p<0.001). Group A maintained −8.4 lbs (−3.5%) and group B maintained −23.1 lbs (−9.0%) at 5 years. In group A, A1C decreased from 7.5±1.3% to 6.7±0.9% at 12 weeks but increased to 7.7±1.4% at 1 year and 8.0±1.9% at 5 years. In group B, A1C decreased from 7.4±1.2% to 6.4±0.9% at 12 weeks and rose to 6.8±1.2% at 1 year and 7.3±1.5% at 5 years. Despite weight regain, group A maintained improvement in low-density lipoprotein-cholesterol and high-density lipoprotein-cholesterol with worsening of serum triglycerides and no change in blood pressure (BP). Group B maintained improvement in lipid profile for 5 years and had significantly lower BP for 18 months. Conclusions Weight reduction in patients with diabetes can be maintained for 5 years and is predicted by patients’ ability to maintain ≥7% weight loss at 1 year. A1C and triglycerides deteriorate with weight regain, while other lipid improvements are maintained. Sustained weight loss is associated with significantly lower A1C for 5 years and lowers BP for 18 months. Trial registration number NCT01937845. PMID:28090332

  7. The response of the ionosphere to intense geomagnetic storms in 2012 using GPS-TEC data from East Africa longitudinal sector

    NASA Astrophysics Data System (ADS)

    Tesema, F.; Damtie, B.; Nigussie, M.

    2015-12-01

    The response of the ionosphere to intense magnetic storms has been studied using total electron content (TEC). TEC data recorded by a series of GPS receivers at a longitude ∼ 35 ° E covering a wide range of latitudes (32 ° S to 68 ° N, geographic) is analyzed to study spatio-temporal modifications of the vertical TEC (vTEC) during storms on 07 and 09 March 2012 and on 14 July 2012. We have observed main phase positive response at equatorial ionization anomaly (EIA) crests and mid latitude regions in all the storms. These main phase positive responses are associated with vertical drift enhancement (intensified equatorial electrojet (EEJ)) and the mechanical effect of equatorward neutral wind after an auroral activity. A daytime substantial depletion of TEC at low latitude region was observed on 08 March 2012. This is due to the combined effects of oversheilding and disturbance dynamo electric field that drive large downward drifts during the day. The low latitude and equatorial ionospheric response in the recovery phase days of March storm is found to be largely associated with the disturbance dynamo field that suppressed the upward E × B drift from EEJ observations. The summer negative and winter positive response in July storm as well as mid latitude positive response in March storm was associated with the composition changes as depicted by the O to N2 ratio from GUVI measurements.

  8. Phytoplankton distribution in the Western Arctic Ocean during a summer of exceptional ice retreat

    NASA Astrophysics Data System (ADS)

    Coupel, P.; Jin, H. Y.; Ruiz-Pino, D.; Chen, J. F.; Lee, S. H.; Li, H. L.; Rafizadeh, M.; Garçon, V.; Gascard, J. C.

    2011-07-01

    A drastic ice decline in the Arctic Ocean, triggered by global warming, could generate rapid changes in the upper ocean layers. The ice retreat is particularly intense over the Canadian Basin where large ice free areas were observed since 2007. The CHINARE 2008 expedition was conducted in the Western Arctic (WA) ocean during a year of exceptional ice retreat (August-September 2008). This study investigates whether a significant reorganization of the primary producers in terms of species, biomass and productivity has to be observed in the WA as a result of the intense ice melting. Both pigments (HPLC) and taxonomy (microscopy) acquired in 2008 allowed to determine the phytoplanktonic distribution from Bering Strait (65° N) to extreme high latitudes over the Alpha Ridge (86° N) encompassing the Chukchi shelf, the Chukchi Borderland and the Canadian Basin. Two different types of phytoplankton communities were observed. Over the ice-free Chukchi shelf, relatively high chl-a concentrations (1-5 mg m-3) dominated by 80 % of diatoms. In the Canadian Basin, surface waters are oligotrophic (<0.1 mg m-3) and algal assemblages were dominated by haptophytes and diatoms while higher biomasses (~0.4 mg m-3) related to a deep Subsurface Chlorophyll Maximum (SCM) are associated to small-sized (nano and pico) phytoplankton. The ice melting onset allows to point out three different zones over the open basin: (i) the ice free condition characterized by deep and unproductive phytoplankton communities dominated by nanoplankton, (ii) an extended (78°-83° N) Active Melting Zone (AMZ) where light penetration associated to the stratification start off and enough nutrient availability drives to the highest biomass and primary production due to both diatoms and large flagellates, (iii) heavy ice conditions found north to 83° N allowing light limitation and consequently low biomass and primary production associated to pico and nanoplankton. To explain the poverty (Canadian Basin) and the

  9. Step-change in retreat rates on Novaya Zemlya outlet glaciers

    NASA Astrophysics Data System (ADS)

    Carr, Rachel; Bell, Heather; Killick, Rebecca; Holt, Tom

    2017-04-01

    Arctic ice masses have rapidly lost ice from the mid-1990s, through a combination of negative surface mass balance and accelerated ice discharge from marine-terminating outlet glaciers. In the past decade, substantial mass deficits have been identified on Novaya Zemlya (NVZ), Russian High Arctic, and its outlet glaciers began to retreat rapidly, from 2000 onwards. However, little is known about longer-term glacier behaviour on NVZ, meaning we have limited context for their recent acceleration in retreat. Here, we greatly extend the available record of glacier retreat, and assess multi-decadal glacier response to forcing between 1976 and 2015, using remotely sensed data. Using statistical changepoint analysis, we demonstrate a significant change in retreat rates for many glaciers, during the early 2000s. We also show that retreat slowed on numerous outlets from 2013 onwards, and that some glaciers even began to advance. NVZ glaciers have previously shown step-like changes in retreat rates, so we cannot determine whether this represents a longer-term trend or short-term slow-down, but it warrants future monitoring. We also assessed spatial patterns of retreat and found no significant differences in retreat rates according to coast or ice mass. Instead, the rate and temporal pattern of retreat were strongly dependant on terminus type: outlets terminating in lakes or the ocean retreated significantly faster than those ending on land. Interestingly, retreat rates on marine- and lake-terminating glaciers were not significantly different. However, the lake-terminating glaciers showed very little variation in retreat rates between glacier or over time, whereas the variability was very large on ocean-terminating glaciers. In terms of climatic controls, significant changes in Jul-Sep sea ice on both coasts of NVZ coincide with the onset of more rapid retreat, but there is large internnual variability in the data.

  10. Recent glacier retreat and climate trends in Cordillera Huaytapallana, Peru

    NASA Astrophysics Data System (ADS)

    López-Moreno, J. I.; Fontaneda, S.; Bazo, J.; Revuelto, J.; Azorin-Molina, C.; Valero-Garcés, B.; Morán-Tejeda, E.; Vicente-Serrano, S. M.; Zubieta, R.; Alejo-Cochachín, J.

    2014-01-01

    We analyzed 19 annual Landsat Thematic Mapper images from 1984 to 2011 to determine changes of the glaciated surface and snow line elevation in six mountain areas of the Cordillera Huaytapallana range in Peru. In contrast to other Peruvian mountains, glacier retreat in these mountains has been poorly documented, even though this is a heavily glaciated area. These glaciers are the main source of water for the surrounding lowlands, and melting of these glaciers has triggered several outburst floods. During the 28-year study period, there was a 55% decrease in the surface covered by glaciers and the snowline moved upward in different regions by 93 to 157 m. Moreover, several new lakes formed in the recently deglaciated areas. There was an increase in precipitation during the wet season (October-April) over the 28-year study period. The significant increase in maximum temperatures may be related to the significant glacier retreat in the study area. There were significant differences in the wet season temperatures during El Niño (warmer) and La Niña (colder) years. Although La Niña years were generally more humid than El Niño years, these differences were not statistically significant. Thus, glaciers tended to retreat at a high rate during El Niño years, but tended to be stable or increase during La Niña years, although there were some notable deviations from this general pattern. Climate simulations for 2021 to 2050, based on the most optimistic assumptions of greenhouse gas concentrations, forecast a continuation of climate warming at the same rate as documented here. Such changes in temperature might lead to a critical situation for the glaciers of the Cordillera Huaytapallana, and may significantly impact the water resources, ecology, and natural hazards of the surrounding areas.

  11. Retreatment of Recurrent Cystic Craniopharyngioma With Chromic Phosphorus P 32

    PubMed Central

    Kumar, P.P.; Good, R.R.; Skultety, F.M.; Jones, E.O.; Chu, W.K.

    1986-01-01

    A cystic craniopharyngioma in a two-year-old boy recurred six months after surgery and postoperative external-beam radiotherapy. Successful retreatment was accomplished with radioisotope injection of 0.5 mCi of chromic phosphorus P 32 into the intracranial cyst, which delivered approximately 300.00 Gy to the cyst wall. The patient's symptoms were relieved, and he is without evidence of disease or cystic fluid accumulation four years after intracavitary 32P irradiation. ImagesFigure 1Figure 2Figure 3 PMID:3735454

  12. Pliocene retreat of Greenland and Antarctic Ice Sheet margins (Invited)

    NASA Astrophysics Data System (ADS)

    Deconto, R. M.; Pollard, D.

    2013-12-01

    The middle Pliocene epoch (~3 million years ago) is often considered an analogue for future global climatic conditions, because global mean temperatures were comparable to projections of future climate at the end of this century. Importantly, some estimates of mid-Pliocene sea level are >20 m higher than today, implying the potential for significant retreat of the East Antarctic Ice Sheet (EAIS), in addition to the loss of the Greenland and West Antarctic Ice Sheets (WAIS). Here, we use a hybrid ice sheet-shelf model with freely migrating grounding lines coupled to a high-resolution regional climate model to test the potential for both West and East Antarctic Ice Sheet retreat during the warm Pliocene and in long-term future scenarios with elevated CO2. In these simulations we apply new treatments of i) ice shelf calving (accounting for the effects of divergent ice flow and surface melt water on crevassing), ii) ice-cliff mechanics at the grounding line, iii) improved sub-glacial bathymetry using BEDMAP2, and iv) a range of plausible ocean warming scenarios based on offline ocean modeling. In warm Pliocene simulations, the combination of improved bathymetric detail and more physically based model treatments of floating and grounded calving fronts substantially increases the rates and magnitudes of ice sheet retreat into over-deepened subglacial basins in both in West and East Antarctica. These new results imply the EAIS margin did indeed contribute to elevated (and orbitally paced) Pliocene sea levels, with Antarctica contributing up to ~20m equivalent sea level during the warmest intervals. In long-term (10^3-4-yr) future simulations using the same model physics, we find these new mechanisms produce a much more sensitive and vulnerable ice sheet than previously considered, with the potential for substantial future retreat of both WAIS and parts of the East Antarctic margin in response to the combined effects of increased surface melt on ice shelf surfaces and

  13. Current concepts in gutta-percha removal in endodontic retreatment.

    PubMed

    Mounce, Rich

    2004-01-01

    Effective removal of gutta-percha (GP) in endodontic retreatment is a significant factor in creating successful outcomes from failed procedures. Ideally, gutta-percha removal must be efficient, not predispose the tooth to subsequent failure through iatrogenic events, and clean the existing canals so that subsequent irrigants can effectively and biomechanically cleanse the root canal system. All things being equal, it is recommended that GP be removed without solvents in the coronal two-thirds of canals as much as possible and with solvents in the apical third. Rotary nickel titanium files and the SystemB heat source (SybronEndo, Orange, CA) are significant adjuncts in effective GP removal.

  14. Retreatability of Root Canals Obturated Using Gutta-Percha with Bioceramic, MTA and Resin-Based Sealers

    PubMed Central

    Uzunoglu, Emel; Yilmaz, Zeliha; Sungur, Derya Deniz; Altundasar, Emre

    2015-01-01

    Introduction: The aim of this study was to evaluate the retreatability of root canals obturated with gutta-percha (GP) and three different endodontic sealers [iRoot SP (bioceramic sealer), MTA Fillapex (MTA-based sealer) and AH-26 (epoxy resin-based sealer)] using the ProTaper Universal Retreatment (PTR) system. Methods and Materials: Forty extracted single-rooted human teeth were prepared with universal ProTaper files up to F4 (40/0.06). Specimens were randomly divided into four groups according to obturation technique/material: single-cone GP/AH-26, lateral compaction of GP/AH-26, single-cone GP/iRoot SP, and single-cone GP/MTA Fillapex. Root fillings were removed with PTR. The time taken to reach the working-length (TWL) was recorded. Roots were longitudinally sectioned and each half was evaluated using a stereomicroscope. Three observers scored each third of all specimen. Obtained data were analyzed using the Kruskal-Wallis, Mann-Whitney U, Welch and Games-Howell tests. The level of significance was set at 0.05. Results: In single-cone GP/MTA Fillapex group the TWL was significantly shorter. The remnant of filling material in the apical and middle thirds of groups was similar and higher than the coronal thirds. Conclusion: None of the tested sealers were completely removed from the root canal system. PMID:25834591

  15. West Antarctic Ice Sheet retreat from Pine Island Bay during the Holocene: New insights into forcing mechanisms

    NASA Astrophysics Data System (ADS)

    Hillenbrand, Claus-Dieter; Smith, James; Kuhn, Gerhard; Poole, Chris; Hodell, David; Elderfield, Harry; Kender, Sev; Williams, Mark; Peck, Victoria; Larter, Robert; Klages, Johann; Graham, Alastair; Forwick, Matthias; Gohl, Karsten

    2013-04-01

    The Amundsen Sea sector of the largely marine-based and therefore conditionally unstable West Antarctic Ice Sheet (WAIS) contains enough ice to raise global sea level by ca. 1.5 metres. At present, ice streams draining this sector into the Southern Ocean, especially glaciers flowing into Pine Island Bay in the eastern Amundsen Sea embayment, are undergoing considerable mass loss characterised by major thinning, flow acceleration and rapid grounding-line retreat. Sub-ice shelf melting by relatively warm Circumpolar Deep Water (CDW) upwelling onto the continental shelf is held responsible for these dynamical changes but atmospheric warming in West Antarctica may also have contributed to them. In contrast to the modern situation, the long-term history of the Amundsen Sea sector and the mechanisms forcing its deglaciation during the Holocene are only poorly constrained. We will present new palaeoenvironmenal data obtained from marine sediment cores collected in Pine Island Bay. The cores targeted shallow sites on the inner continental shelf and successfully recovered sedimentary sequences bearing calcareous microfossils. Radiocarbon ages on these microfossils demonstrate that the grounding line of the WAIS retreated to within ~100 km of its modern position before ca. 10 kyr BP (thousand years before present), which is consistent with an early WAIS retreat from near-coastal locations in the western Amundsen Sea embayment. Currently, there is no evidence that the grounding line had retreated landward of its modern position during the Holocene. Therefore, the chronological constraints may imply that during the last 10 kyr any episodes of fast grounding-line retreat similar to those observed today were short-lived and rare. Preliminary geochemical data from benthic and planktonic foraminifera tests in the cores from Pine Island Bay reveals that intense CDW upwelling coincided with and may have forced the deglaciation of the inner continental shelf. Furthermore, we observe

  16. Ecological Succession, Land use Changes and Soil Organic C Stock in a Lake Retreat Area (Main Ethiopian Rift Valley)

    NASA Astrophysics Data System (ADS)

    Nyssen, J.; Temesgen, H.; Lemenih, M.; Zenebe, A.; Kindu, M.; Haile, M.

    2007-12-01

    In the Main Ethiopian Rift Valley, ecological succession is related to continuous lake retreat (Nyssen et al., 2004). Human activities, through their impact on land use and cover, affect this ecological succession. Through a remote sensing study, we extricated ecological succession and human activity as causative factors for land use and cover changes (LUCC) and explored which impact this has on soil organic C (SOC) stock in lake retreat areas. Remote sensing data used include a Landsat MSS from 1973, a Landsat TM from 1986 and a Landsat ETM+ from 2000. A conventional type of classification was used whereby supervised classification of the 2000 image was supplemented by unsupervised classification of the older datasets. Due to decreased rainfall and water abstraction for intense irrigated agriculture and floriculture in its catchment, Lake Abijata lost 46 % of its area between 2000 and 2006. On the emerged lands, a good ecological succession was observed between 1973 and 1986, with clear evidence for: emerged land -> grassland -> Acacia bushes -> open woodland. Between 1986 and 2000, LUCC tendencies were totally reversed and woody vegetation decreased strongly, indicating increased human impact (Habtamu et al., 2007). Based on an analysis of the Landsat imagery, coupled with soil and land use studies, determinants for SOC stock were found. Firstly, SOC stock significantly differs between cultivated land and grazing land (3301 and 2626 g m-2) on the one hand, and woodland (4594 g m-2) on the other. The strongest explanation of SOC stock is related to the duration of emergence and hence of pedogenesis. Its proxy, elevation, explains much of the variability of SOC (R2 = 0.48). Using a multiple regression model involving elevation and IR reflectance, the SOC stock in the study area could be assessed at 2196 (+ - 1517) g m-2 SOC in 2000, against 3222 (+ - 1639) g m-2 in 1973 (Nyssen et al., 2007), which is related to the post-1986 reversing of ecological succession in

  17. Using a professional writing retreat to enhance professional publications, presentations, and research development with staff nurses.

    PubMed

    Horstman, Patricia; Theeke, Laurie

    2012-01-01

    This article presents the outcomes of a structured writing retreat used with a group of professional nurses from a Magnet-designated hospital. The purpose of the retreat was to enhance nurses' ability to prepare poster presentations, develop manuscripts for peer-reviewed journal submissions, and design new research studies. This staff development retreat can serve as an exemplar for other hospitals desiring to increase dissemination of best practice.

  18. Evaluation of three different rotary systems during endodontic retreatment - Analysis by scanning electron microscopy

    PubMed Central

    Vidal, Flávia-Teixeira; Nunes, Eduardo; Horta, Martinho-Campolina-Rebello; Freitas, Maria-Rita-Lopes-da Silva

    2016-01-01

    Background Endodontic therapy is considered a series of important and interdependent steps, and failure of any of these steps may compromise the treatment outcome. This study aimed to evaluate the effectiveness of three different rotary systems in removing obturation materials during endodontic retreatment using scanning electron microscopy (SEM) analysis. Material and Methods Thirty-six endodontically treated teeth were selected and divided into 3 groups of 10 and 1 control group with 6 dental elements. The groups were divided according to the rotary system used for removing gutta-percha, as follows: G1: ProTaper system; G2: K3 system; G3: Mtwo system; and G4: Control group. Thereafter, the roots were split and the sections were observed under SEM, for analysis and counting of clear dentinal tubules, creating the variable “degree of dentinal tubule patency” (0: intensely clear; 1: moderately clear; 2: slightly clear; 3: completely blocked). The data were subjected to the Friedman and Kruskal-Wallis statistical tests. Results No differences were observed in the “degree of dentinal tubule patency” neither between the root thirds (to each evaluated group) nor between the groups (to each evaluated third). Nevertheless, when the three root thirds were grouped (providing evaluation of all root extension), the “degree of dentinal tubule patency” was lower in G1 than in G3 (p<0.05), but showed no differences neither between G1 and G2 nor G2 and G3. Conclusions No technique was able to completely remove the canal obturation material, despite G1 having shown better results, although without significant difference to G2 Key words:Scanning electron microscopy, NiTi, retreatment. PMID:27034750

  19. Evaluation of three different rotary systems during endodontic retreatment - Analysis by scanning electron microscopy.

    PubMed

    Vidal, Flávia-Teixeira; Nunes, Eduardo; Horta, Martinho-Campolina-Rebello; Freitas, Maria-Rita-Lopes-da Silva; Silveira, Frank-Ferreira

    2016-04-01

    Endodontic therapy is considered a series of important and interdependent steps, and failure of any of these steps may compromise the treatment outcome. This study aimed to evaluate the effectiveness of three different rotary systems in removing obturation materials during endodontic retreatment using scanning electron microscopy (SEM) analysis. Thirty-six endodontically treated teeth were selected and divided into 3 groups of 10 and 1 control group with 6 dental elements. The groups were divided according to the rotary system used for removing gutta-percha, as follows: G1: ProTaper system; G2: K3 system; G3: Mtwo system; and G4: Control group. Thereafter, the roots were split and the sections were observed under SEM, for analysis and counting of clear dentinal tubules, creating the variable "degree of dentinal tubule patency" (0: intensely clear; 1: moderately clear; 2: slightly clear; 3: completely blocked). The data were subjected to the Friedman and Kruskal-Wallis statistical tests. No differences were observed in the "degree of dentinal tubule patency" neither between the root thirds (to each evaluated group) nor between the groups (to each evaluated third). Nevertheless, when the three root thirds were grouped (providing evaluation of all root extension), the "degree of dentinal tubule patency" was lower in G1 than in G3 (p<0.05), but showed no differences neither between G1 and G2 nor G2 and G3. No technique was able to completely remove the canal obturation material, despite G1 having shown better results, although without significant difference to G2 KEY WORDS:Scanning electron microscopy, NiTi, retreatment.

  20. Efficacy of five rotary systems versus manual instrumentation during endodontic retreatment.

    PubMed

    Fariniuk, Luiz Fernando; Westphalen, Vânia Portela Dietzel; Silva-Neto, Ulisses Xavier da; Carneiro, Everdan; Baratto Filho, Flares; Fidel, Sandra Rivera; Fidel, Rivail Antônio Sérgio

    2011-01-01

    The purpose of this study was to evaluate the efficiency of ProFile, GT, ProTaper, Race and K3 rotary instruments compared with hand K-files for removal of gutta-percha during retreatment. Sixty mandibular premolars were instrumented with GT rotary files and filled by thermomechanical compaction of gutta-percha and AH Plus sealer. The teeth are randomly divided into 6 groups of 10 specimens each. The roots were split longitudinally, digital images were created using a flatbed scanner, and the areas with remaining filling material were demarcated using Image Tool 1.21 software. The results indicate that GT left significantly less (p<0.05) remaining filling material (1.18 ± 1.47) than hand (3.70 ± 3.16) and Hero instruments (2.99 ± 2.58). There was no statistically significant difference (p<0.05) among the others techniques: ProFile (1.99 ± 2.66), ProTaper (2.00 ± 1.99) and K3 (2.71 ± 2.87) when compared with GT. In conclusion, GT, ProFile, ProTaper and K3 were more effective in removing gutta-percha than manual and Hero instruments.

  1. Tuberculosis treatment outcomes among retreatment patients registered by private practitioners in Myanmar.

    PubMed

    Win, A N; Edginton, M E; Hinderaker, S G; Minn, N N; Linn, A K

    2012-09-21

    The objectives of this retrospective cohort study were to report treatment outcomes and identify factors associated with treatment failure among all retreatment tuberculosis (TB) patients registered in the public-private mix DOTS programme of Populations Services International-Myanmar over 6 years. Among 3643 retreatment patients, 2657 (73%) were successfully treated and 309 (8.5%) failed. This study shows that retreatment patients who have failed treatment for their first TB episode are almost twice as likely to fail a second time (13.5%). We have identified some key programmatic challenges associated with retreatment TB in the private sector, and steps are being taken to address this issue.

  2. Scientific retreats with 'speed dating': networking to stimulate new interdisciplinary translational research collaborations and team science.

    PubMed

    Ranwala, Damayanthi; Alberg, Anthony J; Brady, Kathleen T; Obeid, Jihad S; Davis, Randal; Halushka, Perry V

    2017-02-01

    To stimulate the formation of new interdisciplinary translational research teams and innovative pilot projects, the South Carolina Clinical and Translational Research (SCTR) Institute (South Carolina Clinical and Translational Science Award, CTSA) initiated biannual scientific retreats with 'speed dating' networking sessions. Retreat themes were prioritized based on the following criteria; cross-cutting topic, unmet medical need, generation of novel technologies and methodologies. Each retreat begins with an external keynote speaker followed by a series of brief research presentations by local researchers focused on the retreat theme, articulating potential areas for new collaborations. After each session of presentations, there is a 30 min scientific 'speed dating' period during which the presenters meet with interested attendees to exchange ideas and discuss collaborations. Retreat attendees are eligible to compete for pilot project funds on the topic of the retreat theme. The 10 retreats held have had a total of 1004 participants, resulted in 61 pilot projects with new interdisciplinary teams, and 14 funded projects. The retreat format has been a successful mechanism to stimulate novel interdisciplinary research teams and innovative translational research projects. Future retreats will continue to target topics of cross-cutting importance to biomedical and public health research. Copyright © 2016 American Federation for Medical Research.

  3. A Palaeohydrological Shift during Neogene East Antarctic Ice Sheet Retreat

    NASA Astrophysics Data System (ADS)

    Rees-Owen, R. L.; Newton, R.; Ivanovic, R. F.; Francis, J.; Tindall, J. C.; Riding, J. B.

    2015-12-01

    The East Antarctic Ice Sheet is an important driver of global climate, playing a particular role in governing albedo and atmospheric circulation (eg. Singh et al., 2013). Recent evidence from marine sediment and terrestrial glaciovolcanic sequences suggests that the EAIS underwent periodic retreat and collapse in response to warmer climates during the late Neogene (14 to 3 million years ago). Mummified prostrate trees recovered from palaeosols at Oliver Bluffs in the Beardmore Glacier region, Transantarctic Mountains (85° S), represent a rare insight into the terrestrial palaeoclimate during one of these periods of retreat. Prostrate trees are an understudied but useful tool for interrogating endmember (e.g. periglacial) environments at high altitudes and latitudes. We present exciting new palaeoclimate data from the sequence at Oliver Bluffs. δ18O analysis of tree ring cellulose suggests that Antarctic summer palaeoprecipitation was enriched relative to today (-25 to -5‰ for ancient, -35 to -20‰ for modern); consistent with our isotope-enabled general circulation model simulations. The MBT/CBT palaeothermometer gives a summer temperature of 3-6ºC, consistent with other palaeobotanical climate indices. These geological and model data have wide-ranging implications for our understanding of the hydrological cycle during this time period. We present data suggesting that changes in moisture recycling and source region indicate a markedly different hydrological cycle.

  4. Insights into lateral marsh retreat mechanism through localized field measurements

    NASA Astrophysics Data System (ADS)

    Bendoni, M.; Mel, R.; Solari, L.; Lanzoni, S.; Francalanci, S.; Oumeraci, H.

    2016-02-01

    Deterioration of salt marshes may be due to several factors related to increased anthropic pressure, sea level rise, and erosive processes. While salt marshes can reach equilibrium in the vertical direction, adapting to sea level rise, they are inherently unstable in the horizontal direction. Marsh boundaries are characterized by scarps with bare sediment below the vegetated surface layer that can be easily removed by wave-induced erosion. In this work, we explore the different mechanisms involved in the erosion of marsh borders through the interpretation of field data. The analysis is based on a systematic field monitoring of a salt marsh in the Venice Lagoon subject to lateral erosion. Measurements included horizontal retreat of the scarp at various locations and wave height in front of the marsh during three storm surges. Continuous erosion and mass failures alternated during the observed period, leading to an average retreat up to 80 cm/yr. The data, collected roughly every month for 1.5 year, indicate that the linear relation that links the observed erosion rate to the impinging wave power exhibits a larger slope than that already estimated in literature on the basis of long-term surveys. Moreover, an increase in the gradient of erodibility is detected along the marsh scarp, due to the combined action of soil strengthening by vegetation on the marsh surface and the impact of wave breaking at the bank toe, which promote cantilever failures and increase the lateral erosion rate.

  5. Modeling Drastic Ice Retreat in Antarctic Subglacial Basins

    NASA Astrophysics Data System (ADS)

    Pollard, D.; Deconto, R. M.

    2013-12-01

    Various data indicate that global mean sea level has fluctuated on O(10,000 to 100,000) year time scales during the last ~25 million years, reaching 20 m or more above modern. If correct, this implies substantial variations in the size of the East Antarctic Ice Sheet (EAIS). However, climate and ice-sheet models have not been able to simulate significant EAIS retreat from continental size, given low proxy atmospheric CO2 levels during this time. Here, we use a new mechanism involving a maximum vertical ice cliff size of ~100 m above the ocean at the grounding line beyond which structural failure occurs, triggered by the complete melting of floating shelves that normally prevent this configuration in large embayments. This is tested in a 3-D ice-sheet model by applying oceanic and climatic warming representing past warm periods, which attacks floating ice shelves by basal melting and by increased calving due to surface melt or rain draining into crevasses. In addition to accelerating the expected collapse of West Antarctic ice, the new mechanisms cause drastic retreat into 3 major East Antarctic subglacial basins, causing ~20 m global sea-level rise within a few thousand years that takes more than 10,000 years to recover. This offers a resolution of the past sea level model-data conflict, but suggests that Antarctica may be more vulnerable to future warming than previously realized.

  6. The 22nd annual prostate cancer foundation scientific retreat report.

    PubMed

    Miyahira, Andrea K; Simons, Jonathan W; Soule, Howard R

    2016-09-01

    The 22nd Annual Prostate Cancer Foundation (PCF) Scientific Retreat was convened in Washington, D.C. from October 8 to 10, 2015. This event is the foremost scientific conference in the world focusing on basic, translational, and clinical prostate cancer research with the highest potential for accelerating the understanding of prostate cancer biology and improving the lives and outcomes of prostate cancer patients. Topics highlighted during the 2015 Retreat included: (i) new strategies and treatments for localized high-risk, hormone-naïve, oligometastatic, castrate-resistant, and treatment-refractory prostate cancer settings; (ii) the biology and genomics of tumor heterogeneity and tumor evolution; (iii) new understandings on the mechanisms and targeting of oncogenic drivers of prostate cancer; (iv) bioengineering of novel therapies and drug delivery methods; (v) innovative approaches to tumor immunotherapy; (vi) emerging molecular imaging technologies with improved sensitivity and specificity; and (vii) advancements in prognostic and predictive biomarkers and precision medicine strategies. Prostate 76:1037-1052, 2016. © 2016 Wiley Periodicals, Inc.

  7. Tundra burning in 2007 - Did sea ice retreat matter?

    NASA Astrophysics Data System (ADS)

    Alexeev, Vladimir A.; Euskirchen, Eugénie S.; Cherry, Jessica E.; Busey, Robert C.

    2015-06-01

    The goal of this study was to assess the importance of the 2007 sea ice retreat for hydrologic conditions on the Alaskan North Slope, and how this may have influenced the outbreak of tundra fires in this region. This study concentrates on two years, 2007 and 1996, with different arctic sea ice conditions and tundra fire activity. The year of 2007 is characterized by a low summer sea ice extent (second lowest) and high tundra fire activity, while 1996 had high sea ice extent, and few tundra fires. Atmospheric lateral boundary forcing from the NCEP/NCAR Reanalysis drove the Weather Research and Forecast (WRF) model, along with varying sea ice surface forcing designed to delineate the role of sea ice. WRF runs successfully reproduced the differences between 1996 and 2007. Surprisingly, replacing sea ice conditions in 1996 run by those from 2007 and vice versa (2007 run with 1996 sea ice) did not change the overall picture. The atmospheric circulation in August of 1996 included a significant low-pressure system over the Beaufort and Chukchi Seas. However, in 2007, a high-pressure system dominated the circulation over the Beaufort Sea. It is argued that this difference in large-scale patterns, rather than retreat of sea ice, was responsible for anomalously dry and warm atmospheric conditions over the North Slope in summer and autumn 2007, suitable for high tundra fire activity. Circulation in 2012 is contrasted with that in 2007 to further stress its importance for local weather on the North Slope.

  8. The Efficacy of the WaveOne Reciprocating File System versus the ProTaper Retreatment System in Endodontic Retreatment of Two Different Obturating Techniques.

    PubMed

    Jorgensen, Ben; Williamson, Anne; Chu, Rene; Qian, Fang

    2017-06-01

    This ex vivo study aimed to evaluate the efficacy of retreating GuttaCore (Dentsply Tulsa Dental Specialties, Tulsa, OK) and warm vertically condensed gutta-percha in moderately curved canals with 2 different systems: ProTaper Universal Retreatment (Dentsply Tulsa Dental) and WaveOne (Dentsply Tulsa Dental). Eighty mesial roots of mandibular molars were used in this study. The mesiobuccal canals in each sample were prepared to length with the WaveOne Primary file (Dentsply Tulsa Dental). The canals were obturated with either a warm vertical approach or with GuttaCore and divided into 4 retreatment groups with the same mean root curvature: warm vertical retreated with ProTaper, warm vertical retreated with WaveOne, GuttaCore retreated with ProTaper, and GuttaCore retreated with WaveOne. The warm vertical groups were obturated using a continuous-wave technique of gutta-percha compaction, and the GuttaCore groups were obturated according to the manufacturer's instructions. After allowing sealer to set, each specimen was retreated with either the ProTaper Universal Retreatment files D1, D2, or D3 or with the WaveOne Primary file to the predetermined working length. The time taken to reach the working length was recorded. Instrument fatigue and failure were also evaluated. The post hoc 2-sample t tests showed that the overall mean total time taken to reach the working length for the warm vertical groups was significantly greater than that observed for the GuttaCore groups (mean = 87.11 vs 60.16 seconds, respectively), and the overall mean total time taken to reach the working length for WaveOne was significantly greater than that observed for ProTaper (99.09 vs 48.18 seconds, respectively). Two-way analysis of variance showed a significant main effect for both the type of experiment groups (F1,76 = 15.32, P = .0002) and the type of retreatments (F1,76 = 54.67, P < .0001). Also, the WaveOne Primary file underwent more separations than the ProTaper files. The

  9. The writing retreat: a high-yield clinical faculty development opportunity in academic writing.

    PubMed

    Cable, Christian T; Boyer, Debra; Colbert, Colleen Y; Boyer, Edward W

    2013-06-01

    The need for consistent academic productivity challenges junior clinician-scholars, who often lack the aptitude to ensure efficient production of manuscripts. To solve this problem, an academic division of a major medical center developed an off-site writing retreat. The purpose of the retreat was not to teach writing skills, but to offer senior mentor assistance with a focus on the elements of manuscript writing. The retreat paired senior faculty members with junior staff. Senior faculty identified manuscript topics and provided real-time writing and editing supervision. Team-building exercises, midcourse corrections, and debriefing interviews were built into the retreat. The number of manuscripts and grant proposals generated during the 2008-2011 retreats was recorded, and the program was evaluated by using unstructured debriefing interviews. An average of 6 to 7 faculty members and fellows participated in each retreat. During the past 4 years, participants produced an average of 3 grant proposals and 7 manuscripts per retreat. After the writing retreat, each fellow and junior faculty member produced an average of 4 scholarly products per year, compared to fewer than 2 for prior years' retreats. Participant feedback indicated the success of the retreat resulted from protected time, direct mentorship by the scholars involved, and pairing of authors, which allows for rapid production of manuscripts and accelerated the editing process. More than 80% of mentors returned each year to participate. The writing retreat is a feasible, effective strategy to increase scholarship among faculty, acceptable to mentees and mentors, and sustainable over time.

  10. Probabilistic estimation of dune retreat on the Gold Coast, Australia

    USGS Publications Warehouse

    Palmsten, Margaret L.; Splinter, Kristen D.; Plant, Nathaniel G.; Stockdon, Hilary F.

    2014-01-01

    Sand dunes are an important natural buffer between storm impacts and development backing the beach on the Gold Coast of Queensland, Australia. The ability to forecast dune erosion at a prediction horizon of days to a week would allow efficient and timely response to dune erosion in this highly populated area. Towards this goal, we modified an existing probabilistic dune erosion model for use on the Gold Coast. The original model was trained using observations of dune response from Hurricane Ivan on Santa Rosa Island, Florida, USA (Plant and Stockdon 2012. Probabilistic prediction of barrier-island response to hurricanes, Journal of Geophysical Research, 117(F3), F03015). The model relates dune position change to pre-storm dune elevations, dune widths, and beach widths, along with storm surge and run-up using a Bayesian network. The Bayesian approach captures the uncertainty of inputs and predictions through the conditional probabilities between variables. Three versions of the barrier island response Bayesian network were tested for use on the Gold Coast. One network has the same structure as the original and was trained with the Santa Rosa Island data. The second network has a modified design and was trained using only pre- and post-storm data from 1988-2009 for the Gold Coast. The third version of the network has the same design as the second version of the network and was trained with the combined data from the Gold Coast and Santa Rosa Island. The two networks modified for use on the Gold Coast hindcast dune retreat with equal accuracy. Both networks explained 60% of the observed dune retreat variance, which is comparable to the skill observed by Plant and Stockdon (2012) in the initial Bayesian network application at Santa Rosa Island. The new networks improved predictions relative to application of the original network on the Gold Coast. Dune width was the most important morphologic variable in hindcasting dune retreat, while hydrodynamic variables, surge and

  11. Modeling the Retreat Processes of Salt Marsh Edge

    NASA Astrophysics Data System (ADS)

    Bendoni, M.; Cappietti, L.; Francalanci, S.; Rinaldi, M.; Solari, L.

    2012-12-01

    Edge erosion of salt marshes due to surface waves and tide forcing is likely the chief mechanism that models marsh boundaries and by which salt marshes in worldwide coastal areas are being lost. In order to address this problem, experimental observations in a laboratory flume and field measurements in the lagoon of Venice were conducted to understand the main processes controlling marsh edge retreat, with a focus on the erosion mechanisms caused by the action of wind and tidal waves. A physical model reproducing a salt marsh bank was built inside a long wave current flume where random surface waves were generated according to a given wave spectrum. The physical model was constructed with the original soil and plants taken in a marsh of the lagoon of Venice, while the wave climate was reproduced according to field measurements. The experiments were conducted in the case of both unvegetated and vegetated bank: a first set of experiments was carried out considering only tidal wave; in the second, bank models experienced the effect of wind waves superimposed to the tide. The following data were collected during the experiments: wave climate interacting with the bank, flow velocity measurements in the eroded quasi-equilibrium configuration, pressure distribution along bank edge and internal pressure fluctuation and damping due to wave impact. Bank geometry profile and bottom topography at different times have also been collected to characterize the erosion rate with time and the evolution of bank retreat. Subsequent to laboratory activity wave climate was measured close to a marsh edge in the Lagoon of Venice with the aim at identifying wave forcing on the bank surface during a moderate wind event and comparing results with the wave stress experienced by bank models in laboratory tests. Several pressure transducers installed close to the bed were used to collect wave height and wave direction with respect to the edge of the marsh. Laboratory data and field measurement

  12. Writing Retreat Increases Productivity And Community For Women Geoscientists

    NASA Astrophysics Data System (ADS)

    O'Connell, S.; Holmes, M.

    2011-12-01

    Five, weeklong geoscientist writing retreats have been completed with an NSF ADANCE PAID grant. During the five nights and four and a half days, eight to twenty-four academics have gathered in a rural setting outside of Boston to get to focus on writing papers and proposals while getting to know each other. Participants range in age and experience from graduate students to emeritus professors. Over twenty papers and proposals acknowledge their production, in part to this writing retreat. Impact extends beyond papers as informal mentoring and discussions at meals and in the evenings centers on succeeding in academia. Research and teaching are foremost in the conversation. Post-docs learn strategies for applying for jobs and grants, and senior professors discuss strategies for working with academic administrations, running departments and mentoring students. They also learn new technologies and perspectives from younger participants. Particularly helpful are discussions on work-life balance. Networking opportunities extend beyond the retreat as participants join each other at their home institutions to give seminars, develop research projects and mentor each other's students. All weeks follow the same format. Participants arrive Sunday and meet during an evening welcome reception. Monday is devoted to writing. Tuesday a writing coach is available. In the morning, using examples from the scientific literature, she discusses strategies and techniques for writing clearly at a group session. During the afternoon, participants work with the coach individually or in small groups to improve their own writing projects. Wednesday evening a skill session is offered on a topic of interest. These have included undergraduate research, NSF funding, productive techniques for dealing with conflict, and generational characteristics and attitudes, which can hamper communication. A Thursday evening wrap-up session prepares participants for Friday's departure. We believe that this model

  13. Longitudinal trends in all healthcare-associated infections through comprehensive hospital-wide surveillance and infection control measures over the past 12 years: substantial burden of healthcare-associated infections outside of intensive care units and "other" types of infection.

    PubMed

    Kanamori, Hajime; Weber, David J; DiBiase, Lauren M; Sickbert-Bennett, Emily E; Brooks, Rebecca; Teal, Lisa; Williams, David; Walters, Elizabeth M; Rutala, William A

    2015-10-01

    Targeted surveillance has focused on device-associated infections and surgical site infections (SSIs) and is often limited to healthcare-associated infections (HAIs) in high-risk areas. Longitudinal trends in all HAIs, including other types of HAIs, and HAIs outside of intensive care units (ICUs) remain unclear. We examined the incidences of all HAIs using comprehensive hospital-wide surveillance over a 12-year period (2001-2012). This retrospective observational study was conducted at the University of North Carolina (UNC) Hospitals, a tertiary care academic facility. All HAIs, including 5 major infections with 14 specific infection sites as defined using CDC criteria, were ascertained through comprehensive hospital-wide surveillance. Generalized linear models were used to examine the incidence rate difference by infection type over time. A total of 16,579 HAIs included 6,397 cases in ICUs and 10,182 cases outside ICUs. The incidence of overall HAIs decreased significantly hospital-wide (-3.4 infections per 1,000 patient days), in ICUs (-8.4 infections per 1,000 patient days), and in non-ICU settings (-1.9 infections per 1,000 patient days). The incidences of bloodstream infection, urinary tract infection, and pneumonia in hospital-wide settings decreased significantly, but the incidences of SSI and lower respiratory tract infection remained unchanged. The incidence of Clostridium difficile infection (CDI) increased remarkably. The outcomes were estimated to include 700 overall HAIs prevented, 40 lives saved, and cost savings in excess of $10 million. We demonstrated success in reducing overall HAIs over a 12-year period. Our data underscore the necessity for surveillance and infection prevention interventions outside of the ICUs, for non-device-associated HAIs, and for CDI.

  14. Efficacy of two rotary retreatment systems in removing Gutta-percha and sealer during endodontic retreatment with or without solvent: A comparative in vitro study.

    PubMed

    Bhagavaldas, Moushmi Chalakkarayil; Diwan, Abhinav; Kusumvalli, S; Pasha, Shiraz; Devale, Madhuri; Chava, Deepak Chowdary

    2017-01-01

    The aim of this in vitro study was to compare the efficacy of two retreatment rotary systems in the removal of Gutta-percha (GP) and sealer from the root canal walls with or without solvent. Forty-eight extracted human mandibular first premolars were prepared and obturated with GP and AH Plus sealer. Samples were then randomly divided into four groups. Group I was retreated with MtwoR rotary system without solvent, Group II was retreated with MtwoR rotary system with Endosolv R as the solvent, Group III with D-RaCe rotary system without solvent, and Group IV with D-RaCe rotary system and Endosolv R solvent. The cleanliness of canal walls was determined by stereomicroscope (×20) and AutoCAD software. Kruskal-Wallis test and Mann-Whitney U-test were used to compare the data. Results showed that none of the retreatment systems used in this study was able to completely remove the root canal filling material. D-RaCe with or without solvent showed significantly (P > 0.05) less filling material at all levels compared to MtwoR with/without solvent. Within the limitation of the current study, D-RaCe rotary retreatment system is more effective in removing filling material from root canal walls when compared to MtwoR rotary retreatment system.

  15. Efficacy of two rotary retreatment systems in removing Gutta-percha and sealer during endodontic retreatment with or without solvent: A comparative in vitro study

    PubMed Central

    Bhagavaldas, Moushmi Chalakkarayil; Diwan, Abhinav; Kusumvalli, S.; Pasha, Shiraz; Devale, Madhuri; Chava, Deepak Chowdary

    2017-01-01

    Objectives: The aim of this in vitro study was to compare the efficacy of two retreatment rotary systems in the removal of Gutta-percha (GP) and sealer from the root canal walls with or without solvent. Materials and Methods: Forty-eight extracted human mandibular first premolars were prepared and obturated with GP and AH Plus sealer. Samples were then randomly divided into four groups. Group I was retreated with MtwoR rotary system without solvent, Group II was retreated with MtwoR rotary system with Endosolv R as the solvent, Group III with D-RaCe rotary system without solvent, and Group IV with D-RaCe rotary system and Endosolv R solvent. The cleanliness of canal walls was determined by stereomicroscope (×20) and AutoCAD software. Kruskal–Wallis test and Mann–Whitney U-test were used to compare the data. Results: Results showed that none of the retreatment systems used in this study was able to completely remove the root canal filling material. D-RaCe with or without solvent showed significantly (P > 0.05) less filling material at all levels compared to MtwoR with/without solvent. Conclusion: Within the limitation of the current study, D-RaCe rotary retreatment system is more effective in removing filling material from root canal walls when compared to MtwoR rotary retreatment system. PMID:28761246

  16. Continued retreat of Thwaites Glacier, West Antarctica, controlled by bed topography and ocean circulation

    NASA Astrophysics Data System (ADS)

    Seroussi, H.; Nakayama, Y.; Larour, E.; Menemenlis, D.; Morlighem, M.; Rignot, E.; Khazendar, A.

    2017-06-01

    The Amundsen Sea sector is experiencing the largest mass loss, glacier acceleration, and grounding line retreat in Antarctica. Enhanced intrusion of Circumpolar Deep Water onto the continental shelf has been proposed as the primary forcing mechanism for the retreat. Here we investigate the dynamics and evolution of Thwaites Glacier with a novel, fully coupled, ice-ocean numerical model. We obtain a significantly improved agreement with the observed pattern of glacial retreat using the coupled model. Coupled simulations over the coming decades indicate a continued mass loss at a sustained rate. Uncoupled simulations using a depth-dependent parameterization of sub-ice-shelf melt significantly overestimate the rate of grounding line retreat compared to the coupled model, as the parameterization does not capture the complexity of the ocean circulation associated with the formation of confined cavities during the retreat. Bed topography controls the pattern of grounding line retreat, while oceanic thermal forcing impacts the rate of grounding line retreat. The importance of oceanic forcing increases with time as Thwaites grounding line retreats farther inland.

  17. Response to therapy following retreatment of serofast early syphilis patients with benzathine penicillin.

    PubMed

    Seña, Arlene C; Wolff, Mark; Behets, Frieda; Van Damme, Kathleen; Martin, David H; Leone, Peter; McNeil, Linda; Hook, Edward W

    2013-02-01

    Persistent nontreponemal titers after treatment are common among patients with early syphilis. We retreated 82 human immunodeficiency virus-negative early syphilis participants who were serofast at 6 months using benzathine penicillin. Only 27% exhibited serological response after retreatment and after an additional 6 months of follow-up.

  18. Exceptional retreat of Novaya Zemlya's marine-terminating outlet glaciers between 2000 and 2013

    NASA Astrophysics Data System (ADS)

    Carr, J. Rachel; Bell, Heather; Killick, Rebecca; Holt, Tom

    2017-09-01

    Novaya Zemlya (NVZ) has experienced rapid ice loss and accelerated marine-terminating glacier retreat during the past 2 decades. However, it is unknown whether this retreat is exceptional longer term and/or whether it has persisted since 2010. Investigating this is vital, as dynamic thinning may contribute substantially to ice loss from NVZ, but is not currently included in sea level rise predictions. Here, we use remotely sensed data to assess controls on NVZ glacier retreat between 1973/76 and 2015. Glaciers that terminate into lakes or the ocean receded 3.5 times faster than those that terminate on land. Between 2000 and 2013, retreat rates were significantly higher on marine-terminating outlet glaciers than during the previous 27 years, and we observe widespread slowdown in retreat, and even advance, between 2013 and 2015. There were some common patterns in the timing of glacier retreat, but the magnitude varied between individual glaciers. Rapid retreat between 2000 and 2013 corresponds to a period of significantly warmer air temperatures and reduced sea ice concentrations, and to changes in the North Atlantic Oscillation (NAO) and Atlantic Multidecadal Oscillation (AMO). We need to assess the impact of this accelerated retreat on dynamic ice losses from NVZ to accurately quantify its future sea level rise contribution.

  19. Teacher Retreating: The Little Known Behavior That Impacts Teaching and Learning

    ERIC Educational Resources Information Center

    Ratcliff, Nancy J.; Carroll, Kimberly L.; Hunt, Gilbert H.

    2014-01-01

    This paper discusses findings from four years of observational research examining classroom climate. Specifically, findings that focused on one powerful teacher behavior (teacher retreating) were examined. These data indicated that teacher retreating was negatively correlated to the amount of instructional interaction occurring between students…

  20. Improving residents' end-of-life communication skills with a short retreat: a randomized controlled trial.

    PubMed

    Szmuilowicz, Eytan; el-Jawahri, Areej; Chiappetta, Laurel; Kamdar, Mihir; Block, Susan

    2010-04-01

    Internal medicine residents are largely unprepared to carry out end-of-life (EOL) conversations. There is evidence that these skills can be taught, but data from randomized controlled trials are lacking. We studied whether a day-long communication skills training retreat would lead to enhanced performance of and confidence with specific EOL conversations. We also studied the effect of the retreat on residents' ability to respond to patient emotions. PGY-2 resident volunteers were randomly assigned to a retreat group or a control group. The retreat involved a combination of teaching styles and skills practice with standardized patients. All participants completed questionnaires and were evaluated carrying out two types of conversations (breaking bad news or discussing direction of care) with a standardized patient before (T1) and after (T2) the intervention phase. Conversations were audio-taped and later rated by a researcher blinded to group assignment and time of assessment. Forty-nine residents agreed to randomization (88%) with 23 residents randomized to the retreat group and 26 to the control group. Compared to controls, retreat participants demonstrated higher T2 scores for breaking bad news, discussing direction of care, and responding to emotion. Comparing T2 to T1, the retreat group's improvement in responding to emotion was statistically significant. The retreat group's confidence improved significantly only for the breaking bad news construct. A short course for residents can significantly improve specific elements of resident EOL conversation performance, including the ability to respond to emotional cues.

  1. The Rhetoric of Strategic Retreat: Carter and the Panama Canal Debate.

    ERIC Educational Resources Information Center

    Sudol, Ronald A.

    1979-01-01

    Discusses President Carter's televised address on the Panama Canal Treaties in terms of five "topoi" for a rhetoric of retreat: timeliness, urgency, value, advantage, and shrewdness. Compares his failure to employ the commonsense arguments that a policy of retreat requires in the televised speech with his more successful impromptu…

  2. Evaluation of a gully headcut retreat model using multitemporal aerial photographs and digital elevation models

    NASA Astrophysics Data System (ADS)

    Campo-Bescós, M. A.; Flores-Cervantes, J. H.; Bras, R. L.; Casalí, J.; Giráldez, J. V.

    2013-12-01

    large fraction of soil erosion in temperate climate systems proceeds from gully headcut growth processes. Nevertheless, headcut retreat is not well understood. Few erosion models include gully headcut growth processes, and none of the existing headcut retreat models have been tested against long-term retreat rate estimates. In this work the headcut retreat resulting from plunge pool erosion in the Channel Hillslope Integrated Landscape Development (CHILD) model is calibrated and compared to long-term evolution measurements of six gullies at the Bardenas Reales, northeast Spain. The headcut retreat module of CHILD was calibrated by adjusting the shape factor parameter to fit the observed retreat and volumetric soil loss of one gully during a 36 year period, using reported and collected field data to parameterize the rest of the model. To test the calibrated model, estimates by CHILD were compared to observations of headcut retreat from five other neighboring gullies. The differences in volumetric soil loss rates between the simulations and observations were less than 0.05 m3 yr-1, on average, with standard deviations smaller than 0.35 m3 yr-1. These results are the first evaluation of the headcut retreat module implemented in CHILD with a field data set. These results also show the usefulness of the model as a tool for simulating long-term volumetric gully evolution due to plunge pool erosion.

  3. Write Away from It All! The Value of Running a Writing Retreat for Doctoral Students

    ERIC Educational Resources Information Center

    Davis, Geraldine; Wright, Hazel; Holley, Debbie

    2016-01-01

    Doctoral candidates often struggle to write at doctoral level. This struggle has many causes, but includes finding the time and support to write. We analyse a doctoral writing retreat aimed to encourage doctoral candidates to develop their academic writing and offer new insights into successful retreats. A comprehensive review of the literature…

  4. Impact of different file systems on the amount of apically extruded debris during endodontic retreatment

    PubMed Central

    Uzunoglu, Emel; Turker, Sevinc Aktemur

    2016-01-01

    Objective: The goal of present study was to determine the effect of different nickel–titanium file systems on the amount of apically extruded debris during endodontic retreatment: D-RaCe retreatment systems, EdgeFile XR retreatment rotary files, and Reciproc R40. Materials and Methods: Thirty-six single-rooted prepared mandibular premolar teeth were filled with Gutta-percha and AH Plus sealer. The teeth were then randomly assigned into three groups (n = 12) for retreatment. The endodontic retreatment was performed as follows: D-RaCe, EdgeFile XR, Reciproc 40. Debris extruded apically during the retreatment was collected into preweighed Eppendorf tubes. An incubator was used to store tubes at 70° C for 5 days. The initial weight was subtracted from final weight of the Eppendorf tubes to calculate the weight of the dry extruded debris for each group. The data obtained were evaluated using Welch analysis of variance and Games-Howell post-hoc tests (P < 0.05). Results: All files resulted in apical extrusion of debris. Reciproc caused significantly less debris extrusion compared to D-RaCe and EdgeFile XR (P < 0.05). Conclusions: The findings revealed that during endodontic retreatment, number, and taper of files might have an influence on the amount of apically extruded debris during endodontic retreatment. PMID:27095898

  5. Outcome of orthograde endodontic retreatment--A two-year follow-up.

    PubMed

    Nesković, Jelena; Zivković, Slavoljub; Medojević, Milica; Maksimović, Milos

    2016-01-01

    Endodontic retreatment is a complex intervention that requires detailed analysis of possible reasons for failure, and flawless practical execution of the procedure. The aim of the study was to assess the outcome of endodontic retreatment based on clinical and radiographic criteria after a two-year observation period. Clinical study included 49 teeth indicated for endodontic retreatment based on periapical index (PAI). All teeth were divided into two groups. Group I comprised teeth without any periapical lesion (PAI score of 1 and 2) while Group II consisted of teeth with visible periapical radiolucency (PAI score of 3, 4, and 5). Endodontic retreatment was completed in two visits with inter-appointment medication of 2% chlorhexidine and calcium hydroxide for two weeks. Outcome of endodontic retreatment was evaluated 12-24 months after final obturation. Endodontic retreatment was successful in 93.3% in Group I after 24 months. In Group II, successful treatment and complete healing was found in 52.9% of teeth, whereas 14.7% of teeth showed only partial healing. However, clinical symptomatology was not present in any of the cases. Considering the absence of clinical signs and subjective symptoms, retreatment was successful in 67.6% of cases where chronic periapical inflammation was present. Endodontic retreatment was successful in high percentage in teeth with and without periapical lesions.

  6. Impact of different file systems on the amount of apically extruded debris during endodontic retreatment.

    PubMed

    Uzunoglu, Emel; Turker, Sevinc Aktemur

    2016-01-01

    The goal of present study was to determine the effect of different nickel-titanium file systems on the amount of apically extruded debris during endodontic retreatment: D-RaCe retreatment systems, EdgeFile XR retreatment rotary files, and Reciproc R40. Thirty-six single-rooted prepared mandibular premolar teeth were filled with Gutta-percha and AH Plus sealer. The teeth were then randomly assigned into three groups (n = 12) for retreatment. The endodontic retreatment was performed as follows: D-RaCe, EdgeFile XR, Reciproc 40. Debris extruded apically during the retreatment was collected into preweighed Eppendorf tubes. An incubator was used to store tubes at 70(°) C for 5 days. The initial weight was subtracted from final weight of the Eppendorf tubes to calculate the weight of the dry extruded debris for each group. The data obtained were evaluated using Welch analysis of variance and Games-Howell post-hoc tests (P < 0.05). All files resulted in apical extrusion of debris. Reciproc caused significantly less debris extrusion compared to D-RaCe and EdgeFile XR (P < 0.05). The findings revealed that during endodontic retreatment, number, and taper of files might have an influence on the amount of apically extruded debris during endodontic retreatment.

  7. The Rhetoric of Strategic Retreat: Carter and the Panama Canal Debate.

    ERIC Educational Resources Information Center

    Sudol, Ronald A.

    1979-01-01

    Discusses President Carter's televised address on the Panama Canal Treaties in terms of five "topoi" for a rhetoric of retreat: timeliness, urgency, value, advantage, and shrewdness. Compares his failure to employ the commonsense arguments that a policy of retreat requires in the televised speech with his more successful impromptu…

  8. Timing of ice retreat alters seabird abundances and distributions in the southeast Bering Sea.

    PubMed

    Renner, Martin; Salo, Sigrid; Eisner, Lisa B; Ressler, Patrick H; Ladd, Carol; Kuletz, Kathy J; Santora, Jarrod A; Piatt, John F; Drew, Gary S; Hunt, George L

    2016-09-01

    Timing of spring sea-ice retreat shapes the southeast Bering Sea food web. We compared summer seabird densities and average bathymetry depth distributions between years with early (typically warm) and late (typically cold) ice retreat. Averaged over all seabird species, densities in early-ice-retreat-years were 10.1% (95% CI: 1.1-47.9%) of that in late-ice-retreat-years. In early-ice-retreat-years, surface-foraging species had increased numbers over the middle shelf (50-150 m) and reduced numbers over the shelf slope (200-500 m). Pursuit-diving seabirds showed a less clear trend. Euphausiids and the copepod Calanus marshallae/glacialis were 2.4 and 18.1 times less abundant in early-ice-retreat-years, respectively, whereas age-0 walleye pollock Gadus chalcogrammus near-surface densities were 51× higher in early-ice-retreat-years. Our results suggest a mechanistic understanding of how present and future changes in sea-ice-retreat timing may affect top predators like seabirds in the southeastern Bering Sea.

  9. Mentored residential writing retreats: a leadership strategy to develop skills and generate outcomes in writing for publication.

    PubMed

    Jackson, Debra

    2009-01-01

    There is an increasing expectation that academic and clinical nurses will contribute to disciplinary and professional discourses through scholarly writing. However, the difficulties and challenges associated with writing for publication mean that many papers will never be written. This current paper describes an innovative approach developed to support skill development and outcomes in writing for publication. Intensive residential writing retreats informed by the principles of servant leadership and incorporating strategies such as mentoring and peer learning were conducted in 2005 and 2007. Positive outcomes and benefits included publications submitted to peer-reviewed journals, as well as positive effects on collegial relationships, and team building. Novice writers benefited from intensive and sustained support and coaching by experienced writers. Organisational benefits included increased participation by staff and research higher degree students in publication activities, enhanced collegial relationships and opportunities for senior established writers to work with inexperienced writers.

  10. Effectiveness of three different retreatment techniques in canals filled with compacted gutta-percha or Thermafil: a scanning electron microscope study.

    PubMed

    Pirani, Chiara; Pelliccioni, Gian Andrea; Marchionni, Silvia; Montebugnoli, Lucio; Piana, Gabriela; Prati, Carlo

    2009-10-01

    This study evaluated the root canal wall morphology under scanning electron microscopy magnification after removal of 2 types of root canal fillings by using ultrasonic tips, nickel-titanium (NiTi) rotary instruments, and hand K-files. Thirty-six extracted roots were filled by using AH Plus (DeTrey-Dentsply, Konstanz, Germany) as a sealer with Thermafil (Tulsa Dental Products, Tulsa, OK) (18 roots) or warm vertically condensed gutta-percha (18 roots). All fillings were removed up to the middle third by using Gates Glidden drills. The retreatment was completed by using K-files (group 1), M-Two NiTi rotary instruments (group 2), or ESI ultrasonic tips (group 3) in 12 roots each. Root canals were irrigated by using 10% ethylenediaminetetraacetic acid and 2.5% NaOCl. The samples were split longitudinally and observed by scanning electron microscopy (100-2000x). The presence of smear layer, filling debris, and the surface profile was evaluated in each picture. Kruskal-Wallis (analysis of variance) and Mann-Whitney tests were used to evaluate the differences between the obturation techniques, the 3 retreatment methods, and the canal thirds (P < .05). Resin sealer tags were observed inside dentinal tubules. No statistical differences (P > .05) were found among the 3 retreatment methods. No statistical differences were observed between Thermafil and vertically compacted warm gutta-percha for each group or between the coronal third used as control, middle, and apical thirds. All retreatment techniques showed similar performances in terms of smear layer morphology, debris, and surface profile. None of them completely removed filling debris from dentinal tubules of apical third.

  11. Cleaning and retreatment protocol for a debonded ceramic restoration

    PubMed Central

    Alonso-Pérez-Barquero, Jorge; Bruguera-Álvarez, August; Agustín-Panadero, Rubén; Fons-Font, Antonio

    2015-01-01

    Objectives: The aim of this article is to propose a resin cement cleaning protocol for use before recementing a debonded restoration. Study Design: Ceramic samples were fabricated from IPS d.sign® and IPS e.max Press® and were treated with hydrofluoric acid etching (HF), or HF+silane (S), or HF+S+adhesive or HF+S+A+resin cement. All samples were placed in a furnace at 650º for one minute in order to attempt to pyrolyze the composite. Each step was examined under scanning electron microscopy (SEM). Results: When the cleaning protocol had been performed, it left a clean and retentive surface. Conclusions: If the restoration is placed in a furnace at 650º for one minute, the composite cement will burn or pyrolyze and disappear, allowing conventional retreatment of the ceramic before rebonding. Key words:Ceramic, debond, surface treatment. PMID:25810843

  12. North Atlantic warming and the retreat of Greenland's outlet glaciers.

    PubMed

    Straneo, Fiammetta; Heimbach, Patrick

    2013-12-05

    Mass loss from the Greenland ice sheet quadrupled over the past two decades, contributing a quarter of the observed global sea-level rise. Increased submarine melting is thought to have triggered the retreat of Greenland's outlet glaciers, which is partly responsible for the ice loss. However, the chain of events and physical processes remain elusive. Recent evidence suggests that an anomalous inflow of subtropical waters driven by atmospheric changes, multidecadal natural ocean variability and a long-term increase in the North Atlantic's upper ocean heat content since the 1950s all contributed to a warming of the subpolar North Atlantic. This led, in conjunction with increased runoff, to enhanced submarine glacier melting. Future climate projections raise the potential for continued increases in warming and ice-mass loss, with implications for sea level and climate.

  13. WHO in retreat: is it losing its influence?

    PubMed Central

    Godlee, F.

    1994-01-01

    WHO says it has three main functions: to set normative standards; to provide technical advice and assistance on medical matters; and to advocate changes in health policy. During its 46 year history the first two functions have been a constant and uncontroversial backbone through which WHO has earned its reputation for scientific excellence. The third function, advocacy, came to the fore with the launch of Health for All in 1977, after which WHO took a key role in influencing international health policy. WHO's friends and critics alike now say that the organisation is losing its influence and retreating into its technical and biomedical shell. This article maps the changes in WHO's approach over the past 46 years and considers whether fears about its loss of influence are justified. Images p1492-a p1492-b p1493-a p1494-a FIG 1 PMID:7804058

  14. Windblown Pliocene diatoms and East Antarctic Ice Sheet retreat

    PubMed Central

    Scherer, Reed P.; DeConto, Robert M.; Pollard, David; Alley, Richard B.

    2016-01-01

    Marine diatoms in tillites along the Transantarctic Mountains (TAMs) have been used to suggest a diminished East Antarctic Ice Sheet (EAIS) during Pliocene warm periods. Updated ice-sheet modelling shows significant Pliocene EAIS retreat, creating marine embayments into the Wilkes and Aurora basins that were conducive to high diatom productivity and rapid accumulation of diatomaceous sediments. Here we show that subsequent isostatic uplift exposed accumulated unconsolidated marine deposits to wind erosion. We report new atmospheric modelling utilizing Pliocene climate and derived Antarctic landscapes indicating that prevailing mid-altitude winds transported diatoms towards the TAMs, dominantly from extensive emerged coastal deposits of the Aurora Basin. This result unifies leading ideas from competing sides of a contentious debate about the origin of the diatoms in the TAMs and their link to EAIS history, supporting the view that parts of the EAIS are vulnerable to relatively modest warming, with possible implications for future sea-level rise. PMID:27649516

  15. Windblown Pliocene diatoms and East Antarctic Ice Sheet retreat

    NASA Astrophysics Data System (ADS)

    Scherer, Reed P.; Deconto, Robert M.; Pollard, David; Alley, Richard B.

    2016-09-01

    Marine diatoms in tillites along the Transantarctic Mountains (TAMs) have been used to suggest a diminished East Antarctic Ice Sheet (EAIS) during Pliocene warm periods. Updated ice-sheet modelling shows significant Pliocene EAIS retreat, creating marine embayments into the Wilkes and Aurora basins that were conducive to high diatom productivity and rapid accumulation of diatomaceous sediments. Here we show that subsequent isostatic uplift exposed accumulated unconsolidated marine deposits to wind erosion. We report new atmospheric modelling utilizing Pliocene climate and derived Antarctic landscapes indicating that prevailing mid-altitude winds transported diatoms towards the TAMs, dominantly from extensive emerged coastal deposits of the Aurora Basin. This result unifies leading ideas from competing sides of a contentious debate about the origin of the diatoms in the TAMs and their link to EAIS history, supporting the view that parts of the EAIS are vulnerable to relatively modest warming, with possible implications for future sea-level rise.

  16. The 21st Annual Prostate Cancer Foundation Scientific Retreat report.

    PubMed

    Miyahira, Andrea K; Simons, Jonathan W; Soule, Howard R

    2015-08-01

    The 21st Annual Prostate Cancer Foundation (PCF) Scientific Retreat was held from October 23-25, 2014, in Carlsbad, CA. This event is the world's foremost scientific meeting focusing on prostate cancer and brings together leading basic, translational and clinical researchers in prostate cancer and other diverse disciplines to discuss the newest findings most likely to advance the understanding of prostate cancer and the clinical care of prostate cancer patients. This year's meeting highlighted themes including: (i) research integrity and standards for scientific reproducibility; (ii) prostate cancer disparities; (iii) mechanisms and models of prostate cancer progression and dormancy; (iv) mechanisms of therapeutic resistance; and (v) advancements in precision medicine treatments, treatment models, and predictive and prognostic biomarkers.

  17. Holocene Glacial Retreat at Walgreen Coast, West Antarctica

    NASA Astrophysics Data System (ADS)

    Lindow, J.; Johnson, J.; Castex, M.; Wittmann, H.; Smith, J.; Lisker, F.; Gohl, K.; Spiegel, C.

    2012-12-01

    The Walgreen Coast of West Antarctica represents one of the most rapidly changing sectors of the West Antarctic Ice Sheet (WAIS). With the fastest ice streams in the whole Antarctic, the WAIS is characterised by rapid thinning and grounding line retreat. Airborne and satellite-based short-term observations show a doubling of the negative net mass balance between 1996-2006 (Rignot et al., 2008). Furthermore, because the WAIS is largely grounded below sea level, continued inland thinning and grounding line retreat could result in rapid ice sheet collapse, which would raise global sea level by between 3-5 m. However, due to remoteness and challenging accessibility, onshore data is limited to a few isolated nunataks making it difficult to assess the long-term evolution of the glacial dynamics along Walgreen Coast. To address this we present new data from two key areas of the Walgreen Coast; the Kohler Range and the Pine Island Bay. Our 10Be surface exposure ages from erratic boulders in the Kohler Range are the first and reveal that this area became ice-free between 8.3 and 12.3 ka. This implies a long-term thinning rate of 3.3 cm/yr and agrees with similar data published from glaciers eastward. Our ages are also consistent with recent deglaciation models which suggest strong thinning after 15 ka and off-shore sediments shows a concurrent lateral ice-shelf front retreat. Our results suggest an ice-cover at least 300 m thicker in the Kohler Range during the early Holocene and that subsequent average thinning occurred on rates one order of magnitude slower than recent satellite measurements show. This implies that the recent trend in ice-sheet thinning results from a recent dynamic changes rather than a response to long-term thinning. To further constrain the lateral deglaciation history along the eastern Walgreen Coast, namely the Pine Island Glacier, we collected additional samples from a chain of islands, located flow-parallel and downstream of the ice-shelf front. We

  18. Reducing roof fall accidents on retreat mining sections

    SciTech Connect

    Mark, C.; Zelanko, J.C.

    2005-12-15

    Pillar recovery continues to be one of the most hazardous activities in underground mining. Global stability, achieved through proper pillar design, is a necessary prerequisite for safe pillar recovery. Local stability means preventing roof falls in the working area. It is achieved by minimizing the 'risk factors' described in this paper. Roof Control Plans developed at each underground coal mine often address both engineering parameters and human behavior issues. These plans are essential to all mining activities, but nowhere are they more important than in pillar recovery. Pillaring leaves little tolerance for error, and mistakes can be deadly. Roof Control Plans must be carefully drawn up to address site-specific conditions, and then carefully implemented and followed. Miners and foremen involved in pillar extraction should be trained to know and understand the plan prior to beginning retreat mining. More details can be found at www.cdc.gov/niosh/mining/pubs/pdfs/rtrog.pdf. 3 figs.

  19. Windblown Pliocene diatoms and East Antarctic Ice Sheet retreat.

    PubMed

    Scherer, Reed P; DeConto, Robert M; Pollard, David; Alley, Richard B

    2016-09-20

    Marine diatoms in tillites along the Transantarctic Mountains (TAMs) have been used to suggest a diminished East Antarctic Ice Sheet (EAIS) during Pliocene warm periods. Updated ice-sheet modelling shows significant Pliocene EAIS retreat, creating marine embayments into the Wilkes and Aurora basins that were conducive to high diatom productivity and rapid accumulation of diatomaceous sediments. Here we show that subsequent isostatic uplift exposed accumulated unconsolidated marine deposits to wind erosion. We report new atmospheric modelling utilizing Pliocene climate and derived Antarctic landscapes indicating that prevailing mid-altitude winds transported diatoms towards the TAMs, dominantly from extensive emerged coastal deposits of the Aurora Basin. This result unifies leading ideas from competing sides of a contentious debate about the origin of the diatoms in the TAMs and their link to EAIS history, supporting the view that parts of the EAIS are vulnerable to relatively modest warming, with possible implications for future sea-level rise.

  20. GPCR Retreat 2014: a good view leads to many discoveries!

    PubMed

    Chidiac, Peter; Hébert, Terence E

    2015-06-01

    The GPCR gods smiled on us last year as the 15th Annual GPCR Retreat was held last October 2nd-4th in Bromont, Québec. The fall colors were at their peak and the meeting attendees were also in fine form. The program was one of the best we have seen at any GPCR-related meeting in years and there was a great deal of excitement about new methodological approaches to understanding receptor biology, new concepts in GPCR signaling and a continued emphasis on translation of these discoveries. This year was also the first year we opened the meeting with a short course on biased agonism and how to measure and analyze it.

  1. Radio hyperthermia for re-treatment of superficial tumours.

    PubMed

    Gabriele, P; Ferrara, T; Baiotto, B; Garibaldi, E; Marini, P G; Penduzzu, G; Giovannini, V; Bardati, F; Guiot, C

    2009-05-01

    Relapse remains an unsolved problem for previously radio-treated patients. Our purpose is to evaluate the role of radio-hyperthermia (RT-HT) in the retreatment of superficial recurrences. From 1998 to 2007, 51 patients affected by four histological types (breast recurrences (group A), melanoma recurrences (group B), head and neck recurrences (group C), and others (group D)) of 76 superficial lesions, were enrolled at Mauriziano Hospital at the Research Institute of Cancer Care Candiolo (IRCC) in Turin. All patients had previously undergone RT except 6 patients of group B. The total mean retreatment dose was 31.8 Gy (20-60 Gy), while the mean of HT sessions was 5 (1 to 8), temperature ranged from 38.5 degrees C (T min) to 44 degrees C (T max). Acute cutaneous toxicity was 77.6% G1, 22.4% G2, none for G3. Forty-five days later we observed: for group A 65.9% complete response (CR), 29.5% partial response (PR), 4.5% non-response (NR); for group B 33.3% CR, 25% PR and 41.7% NR; for group C 40% CR, 13.3% PR, 46.7% NR, for group D 60% CR and 40% NR. 18 months later group A presented 72.7% local control (LC), 20.5% stable disease (SD) and 6.8% non-control (NC), group B 50% LC, 16,7% SD and 33.3% NC, group C 33.3% LC, 40% SD and 26.7% NC, group D 40% LC and 60% NC. Early response, size of lesions < or =3 cm, T max > or =42 degrees C and RT doses > or =40 Gy were predictive outcome factors. We confirmed that radio-hyperthermia is useful in re-irradiation with a very high patient compliance.

  2. Physical Mechanisms of Coastal Fog Retreat From Aircraft Observations

    NASA Astrophysics Data System (ADS)

    Layne, J.; Thresher, S.; Heus, T.; Chuang, P. Y.; Sorooshian, A.; Crosbie, E.; Jonsson, H.; Dadashazar, H.; MacDonald, A.

    2016-12-01

    The FASE (Fog and Stratocumulus Evolution) experiment occurred during July-Aug 2016 off the coast of California. One focus of FASE was to examine the moisture and energy budgets of retreating coastal fog using in situ aircraft observations. Each of the 4 flights to examine this question identified a study area 30 km long (parallel to the coastline) and 20 km wide (perpendicular to the coastline) between northern and central California, and at its closest, about 5 km from the coast. The boundary layer budget terms - advection, surface flux, entrainment flux, drizzle, radiative divergence (for energy budget only) and tendency - are estimated from in situ measurements. Preliminary results show that the budget terms balance to within 10% of the largest terms, which we find acceptable within observational uncertainty. The main finding is that entrainment is primarily responsible for fog retreat. If this result is more generally realized, it implies that the response of fog to greenhouse warming may depend on a wide range of properties including (a) large-scale changes to the Hadley circulation through changes in the large-scale subsidence rate and the fog-top inversion strength; (b) the presence of high clouds, through changes in the longwave divergence at fog top; (c) changes in coastal SST, which affects the boundary layer temperature; and (d) the strength of the coastal jet, through modulation of the near-coast subsidence rate. Simulations seeking to predict future fog not only have to capture changes across this wide range of scales, they also must accurately compute fog-top entrainment, which remains an ongoing challenge for even the highest resolution present-day models. Next, these observations will be used as constraints to evaluate the ability of large eddy simulations to represent coastal fog.

  3. Trench Retreat and Migration, a Parameterised Model Approach.

    NASA Astrophysics Data System (ADS)

    Grima, A. G.; Lithgow-Bertelloni, C. R.; Crameri, F.

    2016-12-01

    On Earth, trench rollback is a common feature of subduction zones, particularly at ocean-ocean convergence zones and is often used to explain Tethyan kinematics and the resulting surface strain and deformation. However, the extent and effect of the individual parameters directly influencing trench rollback are not well constrained. In this work we will be presenting a 2-D self-consistent, one sided subduction model with trench rollback through time. Our model is solved by the finite difference/volume multigrid code StagYY [Tackley, 2008] using the `sticky air' approach. Our initial condition is one of an already active subduction, with a ridge at the edge of the subducting plate. Slab rollback and hence trench retreat only starts once the slab hits a viscosity contrast in the lower mantle. This study focuses on and compares the main drivers of subduction such as the plate-mantle viscosity contrast, the slab buoyancy and the geometry and direction of subduction in an attempt to identify the main drivers of slab rollback. We also investigate the effect of slab yield stress, mantle wind and drag, viscous plate bending, trench width and the overriding plate topography. We try to identify which of these parameters are most important for trench roll back initiation and if any other factors are required to sustain the interplay between the gravitational and viscous forces that produce rollback. We further analyse the rates of rollback against plate velocity and the importance of mantle wedge and deep dynamics. This approach tests different types of subduction parameters and the resulting trench retreat (e.g. slow slabs with higher sinking resistance vs. highly negative buoyant slabs) in an attempt to identify the key players in slab rollback. This will not only allows us to understand both slab and mantle behaviour at various depths with different viscosities, but will also provide insight into subduction dynamics both at present day and in the past.

  4. Regional and global forcing of glacier retreat during the last deglaciation.

    PubMed

    Shakun, Jeremy D; Clark, Peter U; He, Feng; Lifton, Nathaniel A; Liu, Zhengyu; Otto-Bliesner, Bette L

    2015-08-21

    The ongoing retreat of glaciers globally is one of the clearest manifestations of recent global warming associated with rising greenhouse gas concentrations. By comparison, the importance of greenhouse gases in driving glacier retreat during the most recent deglaciation, the last major interval of global warming, is unclear due to uncertainties in the timing of retreat around the world. Here we use recently improved cosmogenic-nuclide production-rate calibrations to recalculate the ages of 1,116 glacial boulders from 195 moraines that provide broad coverage of retreat in mid-to-low-latitude regions. This revised history, in conjunction with transient climate model simulations, suggests that while several regional-scale forcings, including insolation, ice sheets and ocean circulation, modulated glacier responses regionally, they are unable to account for global-scale retreat, which is most likely related to increasing greenhouse gas concentrations.

  5. Multi-temporal retreat rates along the eastern Mediterranean coastal cliff

    NASA Astrophysics Data System (ADS)

    Katz, O.; Mushkin, A.

    2012-12-01

    The Israeli coastal cliff extends about 50 km along the eastern Mediterranean shores. The cliff is comprised of late Quaternary eolianites and paleosols and reaches heights of up to 50 meters. In places, time-averaged inland cliff-top retreat rates of up to a few tens of centimeters per year have been measured usually by comparing aerial photos from the last decades. Commonly, these locally constrained retreat rates have been: 1) extrapolated as representative of the entire cliff length, and 2) adopted by hazard-mitigation and planning authorities. Here, we re-evaluate the current understanding of coastal-retreat patterns and rates along Israel's Mediterranean cliff line using a suite of field observations, aerial photography and recently obtained airborne and ground based high resolution LiDAR measurement of cliff morphologies. First, we constrain the decadal-scale retreat rates along the coastal-cliff by comparing the cliff-top location in 1945 and 2004 using aerial photos. We find a statistically significant spatial correlation between: 1) calculated low retreat rates (less than 0.1 m/yr) and field-based criteria indicating overall stability: slope angle of 45 deg. and talus cover along the lower part of the cliff and developed vegetation cover, and 2) high retreat rates and field criteria indicating recent instability: fresh landslide scars and 'hanging' valleys, which provides independent support for the calculated retreat rates. Calculated 60 years average cliff-top retreat rates of less than 0.1, 0.2 and 0.3 m/yr along 58%, 77% and 85% of the cliff length, respectively, reveal that extended stretches of the cliff line did not experience detectable retreat in the past 60 years, thus implying relative stability of 50% of Israel's costal cliffs during this time period. Second, we constrain the annual retreat rates using repeat high-resolution ground based LiDAR surveys before and after an extreme winter storm that occurred in Dec. 2010. Locally, storm induced

  6. Regional and global forcing of glacier retreat during the last deglaciation

    PubMed Central

    Shakun, Jeremy D.; Clark, Peter U.; He, Feng; Lifton, Nathaniel A.; Liu, Zhengyu; Otto-Bliesner, Bette L.

    2015-01-01

    The ongoing retreat of glaciers globally is one of the clearest manifestations of recent global warming associated with rising greenhouse gas concentrations. By comparison, the importance of greenhouse gases in driving glacier retreat during the most recent deglaciation, the last major interval of global warming, is unclear due to uncertainties in the timing of retreat around the world. Here we use recently improved cosmogenic-nuclide production-rate calibrations to recalculate the ages of 1,116 glacial boulders from 195 moraines that provide broad coverage of retreat in mid-to-low-latitude regions. This revised history, in conjunction with transient climate model simulations, suggests that while several regional-scale forcings, including insolation, ice sheets and ocean circulation, modulated glacier responses regionally, they are unable to account for global-scale retreat, which is most likely related to increasing greenhouse gas concentrations. PMID:26293133

  7. Modelling the palaeo grounding-line retreat dynamics of the Uummannaq Ice Stream in Western Greenland.

    NASA Astrophysics Data System (ADS)

    Jamieson, Stewart; Vieli, Andreas; Roberts, Dave; Rea, Brice; Lane, Tim; Cofaigh, Colm Ó.

    2013-04-01

    We aim to understand what controlled the retreat pattern of the Uummannaq Ice Stream (UIS) during the last deglaciation. The ice stream was grounded close to the continental shelf edge at the Last Glacial Maximum, and retreated rapidly after 14.8 ka. Cosmogenic nuclide exposure dating on Ubekendt Island at the convergence zone of multiple feeder ice streams show that the ice surface thinned progressively and that the island became ice-free by ca. 12.4 ka. The ice stream then collapsed over the next 1-1.6 kyrs and the ice stream separated into a series of distinct inland arms. However, it is currently unclear what controlled the nonlinear retreat pattern identified in the Uummannaq system. We test the hypothesis that the geometry of the landscape strongly conditions the rate of retreat of the UIS. In order to do this, we constrain a numerical model of ice stream retreat using the marine geophysical data and measurements of sediment strength on the continental shelf. The model has the capability to dynamically and robustly simulate grounding line-retreat behaviour over millennial timescales. We simulate the retreat of the UIS grounding line into the northernmost Rinks system and conduct sensitivity tests to explore its response to a range of forcing patterns. The model is initialised at a steady-state LGM configuration and is subjected to a series of retreat perturbations forced by either rising sea-level, enhanced melting at the ice-ocean interface, or warming climate. We compare the simulated dynamic behaviour of the UIS against the terrestrial record of ice stream retreat to determine why retreat during the last deglaciation was nonlinear.

  8. Comparison of ProTaper and Mtwo retreatment systems in the removal of resin-based root canal obturation materials during retreatment.

    PubMed

    Iriboz, Emre; Sazak Öveçoğlu, Hesna

    2014-04-01

    To evaluate the effectiveness of the ProTaper and Mtwo retreatment systems for removal of resin-based obturation techniques during retreatment. A total of 160 maxillary anterior teeth were enlarged to size 30 using ProTaper and Mtwo rotary instruments. Teeth were randomly divided into eight groups. Resilon + Epiphany, gutta-percha + Epiphany, gutta-percha + AH Plus and gutta-percha + Kerr Pulp Canal Sealer (PCS) combinations were used for obturation. ProTaper and Mtwo retreatment files were used for removal of root canal treatments. After clearing the roots, the teeth were split vertically into halves, and the cleanliness of the canal walls was determined by scanning electron microscopy. Specimens obturated with gutta-percha and Kerr PCS displayed significantly more remnant obturation material than did specimens filled with resin-based obturation materials. Teeth prepared with Mtwo instruments contained significantly more remnant filling material than did teeth prepared with ProTaper. ProTaper files were significantly faster than Mtwo instruments in terms of the mean time of retreatment and time required to reach working length. The Resilon + Epiphany and AH Plus + gutta-percha obturation materials were removed more easily than were the Epiphany + gutta-percha and Kerr PCS + gutta-percha obturation materials. Although ProTaper retreatment files worked faster than did Mtwo retreatment files in terms of removing root canal obturation materials, both retreatment systems are effective, reliable and fast. © 2012 The Authors. Australian Endodontic Journal © 2012 Australian Society of Endodontology.

  9. Glacier retreat and projected river regime changes in the hydrologically highly-coupled Virkisjökull catchment, Iceland

    NASA Astrophysics Data System (ADS)

    Flett, Verity; Kirkbride, Martin; Black, Andrew; Everest, Jez; MacDonald, Alan

    2016-04-01

    Virkisjökull, an outlet glacier of the Oræfajökull icecap in SE Iceland, currently has 60% glacier cover, though this is reducing due to glacier retreat. Intensive monitoring over the last 4 years includes measurement of measuring ice ablation, proglacial discharge, dye-tracing of flow pathways, and deployment of three automatic weather stations at altitudes up to 880 m. These data calibrate a distributed hydrological model (WaSIM) to project potential river regime during stages of glacier retreat. Results show: (1) glacier hypsometry sensitises the catchment to a disproportionately rapid increase in runoff as the snowline rises onto a gentle ice cap resulting in in a potential annual increase in river discharge of up to 37% (2) a dominantly channelized glacial drainage system in all seasons with a rapid runoff response to melt: englacial flow of 0.58 m s-1 is comparable to the proglacial river velocity; and (3) longer-term, reduced glacier cover and snow storage will lead to a discharge regime dominated by short-term precipitation events in all seasons, and a reduced influence of the seasonal meltwater discharge peak. The study demonstrates the importance of glacier hypsometry above the present ELA as an influence on catchment hydrological response to potential climate warming.

  10. Enhancing the research and publication efforts of health sciences librarians via an academic writing retreat

    PubMed Central

    Bullion, John W.; Brower, Stewart M.

    2017-01-01

    Background: This case study describes the South Central Chapter of the Medical Library Association (SCC/MLA) initiative to develop an academic writing retreat for members who sought the necessary time and support to advance their research projects toward publication. Case Presentation: SCC/MLA staged a dedicated writing retreat to coincide with the organization’s 2012, 2013, and 2014 annual meetings. Each cohort met over two days to write and to workshop their peers’ manuscripts. Organizers distributed an online survey one month after each retreat to evaluate attendees’ perceptions. Conclusions: Three years’ worth of writing retreats yielded fourteen peer-reviewed articles and one book chapter. Participants indicated that the retreat helped them meet or exceed their writing goals by offering protected time and a setting conducive to productivity. The format of the retreat is cost effective and easily adaptable for fellow professionals who wish to organize a formal event as a conference offering or simply support a writing group at their home institutions. In SCC/MLA, the retreat revitalized interest in writing and demystified the scholarly publication process. PMID:28983203

  11. Glacier retreat monitoring from SAR coherence images: application to Gangotri glacier

    NASA Astrophysics Data System (ADS)

    Varugu, Bhuvan K.; Rao, Yalamanchili S.

    2016-05-01

    Retreat of glaciers is an important phenomenon to be monitored as they have a direct bearing on flow of water in rivers and rise of water level in sea. Use of Synthetic Aperture Radar (SAR) images in glacier dynamics studies has been gaining interest in the recent years. The present study discusses the use of SAR coherence images for demarking the snout position on a glacier and thus measure the retreat. Being sensitive for even the slightest changes over the terrain, SAR coherence images seems to be very useful in glacier retreat measurement. Gangotri is one of the major Himalayan glaciers which has been subjected to dominant retreat since 1850 AD.16 The retreat of Gangotri glacier has a huge impact on the flow of Ganges, the largest perennial river in India. Coherence images were generated over Gangotri glacier from SAR images with different repeat periods from 1996 (ERS-1 & 2), 2004 (Envisat) & 2012 (TerraSAR-X) and are resampled to 50x50 m grid using SRTM DEM. Profiles near the snout position were precisely marked in a GIS environment and the distance between the profiles (1996, 2004, 2012) is reported as retreat. It has been observed that the Gangotri glacier has been retreating at the rate of 24+/- 1 m per year which is in good agreement with several other studies.

  12. Loitering of the retreating sea ice edge in the Arctic Seas.

    PubMed

    Steele, Michael; Ermold, Wendy

    2015-12-01

    Each year, the arctic sea ice edge retreats from its winter maximum extent through the Seasonal Ice Zone (SIZ) to its summer minimum extent. On some days, this retreat happens at a rapid pace, while on other days, parts of the pan-arctic ice edge hardly move for periods of days up to 1.5 weeks. We term this stationary behavior "ice edge loitering," and identify areas that are more prone to loitering than others. Generally, about 20-25% of the SIZ area experiences loitering, most often only one time at any one location during the retreat season, but sometimes two or more times. The main mechanism controlling loitering is an interaction between surface winds and warm sea surface temperatures in areas from which the ice has already retreated. When retreat happens early enough to allow atmospheric warming of this open water, winds that force ice floes into this water cause melting. Thus, while individual ice floes are moving, the ice edge as a whole appears to loiter. The time scale of loitering is then naturally tied to the synoptic time scale of wind forcing. Perhaps surprisingly, the area of loitering in the arctic seas has not changed over the past 25 years, even as the SIZ area has grown. This is because rapid ice retreat happens most commonly late in the summer, when atmospheric warming of open water is weak. We speculate that loitering may have profound effects on both physical and biological conditions at the ice edge during the retreat season.

  13. Do rapidly retreating valley glaciers increase catchment sediment export rates?

    NASA Astrophysics Data System (ADS)

    Lane, Stuart; Bakker, Maarten; Gabbud, Chrystelle; Micheletti, Natan; Saugy, Jean-Noël

    2016-04-01

    In the face of rapid climate warming, rapid glacier recession should lead to a marked increase in the spatial extent of paraglacial processes operating in glaciated drainage basins. The paraglacial phase has been well established to be transient but there are very few studies of this transient response and what it means for sediment export. There is good reason to expect that glacier recession could increase basin-scale sediment connectivity as: sediment becomes less dependent on glacier surface transport; proglacial streams are more able to migrate laterally than subglacial streams and so access sediment for transport; and glacier debuttressing may aid the development of gullies that can dissect moraines and so aid hillslope to proglacial zone connectivity. By using records of the flushing of hydroelectric power installations we were able to develop a record of coarse sediment (sand and gravel) export from a basin with a rapidly retreating valley glacier, the Haut Glacier d'Arolla, from 1977 to 2014. Modelling suggested that these data could only be partially controlled by transport capacity implying an important role for sediment supply and potentially for the influence of changing sediment connectivity. Indeed, there was evidence of the effects of glacial debuttressing upon gullying processes and hence a possible increase in the ease of connection of upstream basins to the proglacial area. More recently, it was possible to show possible temperature control on sediment export, which may only have become apparent because of the progressive development of better sediment connectivity. However, whilst rapid glacier recession should result in theory in a progressive increase in connectivity of sediment sources to the basin outlet, the supply to capacity ratio does not increase continually with glacier recession until maximum capacity is reached. We identify two examples of why. First, gullying was also accompanied by the sediment accumulation at the base of moraines

  14. Bathymetric Controls On Observed Tidewater Glacier Retreat In Northwest Greenland

    NASA Astrophysics Data System (ADS)

    Porter, D. F.; Tinto, K. J.; Boghosian, A.; Cochran, J. R.; Bell, R. E.

    2013-12-01

    Although many of the largest glaciers in Greenland are losing mass, the large variability in observed mass wastage of the remaining glaciers clouds interpretation of the proposed external forcings, such as warming of the ocean or atmosphere. Some glaciers are accelerating and thinning while other nearby glaciers advance and gain mass. Recent efforts suggest that increased ocean temperatures may be responsible for the observed glacial retreat in Greenland and Antarctica through increased basal melting beneath floating ice tongues and vertical ice faces of tidewater glaciers. Basal melting may contribute significantly to calving and thinning, and to an eventual speeding up of the glacier, resulting in thinning further inland. Knowledge of fjord geometry is crucial for ice-ocean interaction because the availability of ocean heat to the ice will be restricted by narrow sills and shallow grounding lines. We investigate whether the variability in observed changes among Greenland glaciers can be partially explained by variation in fjord geometry. Some features of a fjord that could influence the ice-ocean system include the depth of the grounding line, the presence of sills, sloping bed, and the water cavity shape beneath floating ice. New estimates of fjord bathymetries in northwest Greenland, using airborne gravimetry measurements from NASA Operation IceBridge flights, are compared to estimates of ice acceleration and mass wastage of neighboring glaciers. We investigate the correlation between fjord geometry features and several glacier parameters, such as surface velocity and elevation changes. We determine that the geometry of glacial fjords play a large role in determining the stability of outlet glaciers. Deep sills and deep terminus grounding lines will allow greater interaction with the deep and warm Atlantic water off the shelf break. For two neighboring glaciers in northwest Greenland, we find that the glacier with a deeper grounding line, and presumably in

  15. Oval-shaped canal retreatment with self-adjusting file: a micro-computed tomography study.

    PubMed

    Keleş, Ali; Alcin, Hatice; Kamalak, Aliye; Versiani, Marco A

    2014-05-01

    The aim of this study was to assess the efficacy of removing the filling material from oval-shaped canals with rotary retreatment files, with or without the additional use of self-adjusting file (SAF), using micro-computed tomography. Oval-shaped canals from 20 maxillary premolars were prepared and assigned to two groups (n = 10), according to the obturation technique: cold lateral condensation (CLC) or vertical condensation (VC). Then, retreatment procedure was performed with retreatment rotary instruments followed by SAF. The specimens were scanned after each procedure and the volume of the filling material calculated. Median and interquartile range (IQR) percentages of the remaining filling material after each retreatment technique were statistically compared by Wilcoxon and Mann–Whitney U tests with a significance level of 5 %. The median percentage volume of the filling residue after rotary retreatment procedure was 1.59 (IQR = 1.26) and 0.42 (IQR = 0.86) in the CLC and VC groups, respectively (p < 0.05). After the use of SAF, the median percentage was 1.26 (IQR = 0.75) and 0.12 (IQR = 0.53) in the CLC and VC groups, respectively (p < 0.05). Statistically significant difference was also observed within the group after the additional use of SAF (p < 0.05). None of the retreatment procedures completely removed the filling material. The additional use of the SAF improved the removal of filling material after the retreatment procedure with rotary instruments. Filling material left after retreatment procedure may harbour necrotic tissue and bacteria, which could lead to a persistent disease and reinfection of the root canal system. The additional use of self-adjusting file after the conventional retreatment procedures may improve root canal cleanliness, allowing a better action of the irrigating solution.

  16. Fracture Resistance of Endodontically Retreated Roots After Retreatment Using Self-Adjusting File, Passive Ultrasonic Irrigation, Photon-Induced Photoacoustic Streaming, or Laser.

    PubMed

    Kamalak, Aliye; Uzun, Ismail; Arslan, Hakan; Keleş, Ali; Doğanay, Ezgi; Keskin, Cangül; Akçay, Merve

    2016-10-01

    Additional cleaning techniques and devices are required to remove maximum amount of residual filling material, which might limit disinfection of root canal system during retreatment. This study aimed to compare fracture resistance of roots when self-adjusting file (SAF), photon-induced photoacoustic streaming (PIPS), passive ultrasonic irrigation (PUI), erbium-doped yttrium aluminum garnet (Er:YAG), or neodymium-doped yttrium aluminum garnet (Nd:YAG) lasers are applied following the use of retreatment files in endodontics. A total of 117 human mandibular canine teeth of similar dimensions were selected and divided into nine groups (n = 13). Aside from control, instrumented, and only-prepared groups, 91 teeth were remaining, of which 13 were assigned to the only-filling group and final 78 to retreatment, thus R-Endo file, R-Endo+SAF, R-Endo+PUI, R-Endo+Er:YAG laser, R-Endo+Nd:YAG laser, and R-Endo+PIPS. The fracture strengths of the retreatment groups were lower than control, instrumented, and only-filling groups (p < 0.05). There was no difference between the R-Endo group and additional retreatment procedure groups (p > 0.05). Further cleaning methods using SAF, PIPS, Er:YAG laser, Nd:YAG laser, or PUI did not decrease the fracture resistance when compared with the R-Endo group.

  17. High Mortality Associated with Retreatment of Tuberculosis in a Clinic in Kampala, Uganda: A Retrospective Study

    PubMed Central

    Acuña-Villaorduña, Carlos; Ayakaka, Irene; Dryden-Peterson, Scott; Nakubulwa, Susan; Worodria, William; Reilly, Nancy; Hosford, Jennifer; Fennelly, Kevin P.; Okwera, Alphonse; Jones-López, Edward C.

    2015-01-01

    The World Health Organization recommends for tuberculosis retreatment a regimen of isoniazid (H), rifampicin (R), ethambutol (E), pyrazinamide (Z), and streptomycin (S) for 2 months, followed by H, R, E, and Z for 1 month and H, R, and E for 5 months. Using data from the National Tuberculosis and Leprosy Program registry, this study determined the long-term outcome under programmatic conditions of patients who were prescribed the retreatment regimen in Kampala, Uganda, between 1997 and 2003. Patients were traced to determine their vital status; 62% (234/377) patients were found dead. Having ≤ 2 treatment courses and not completing retreatment were associated with mortality in adjusted analyses. PMID:25940196

  18. Clinical microscopic analysis of ProTaper retreatment system efficacy considering root canal thirds using three endodontic sealers.

    PubMed

    Só, Marcus Vinícius Reis; De Figueiredo, Jose Antônio Poli; Freitas Fachin, Elaine Vianna; Húngaro Duarte, Marco Antônio; Pereira, Jefferson Ricardo; Kuga, Milton Carlos; Da Rosa, Ricardo Abreu

    2012-09-01

    To evaluate the efficacy of ProTaper Universal rotary retreatment system and the influence of sealer type on the presence of filling debris in the reinstrumented canals viewed in an operative clinical microscope. Forty-five palatal root canals of first molars were filled with gutta-percha and one of the following sealers: G1, EndoFill; G2, AH Plus; G3, Sealapex. The canals were then reinstrumented with ProTaper Universal rotary system. Roots were longitudinally sectioned and examined under an operative clinical microscope (10×), and the amount of filling debris on canal walls was analyzed using the AutoCAD 2004 software. A single operator used a specific software tool to outline the canal area and the filling debris area in each third (cervical, middle, and apical), as well as the total canal area. Data were analyzed by Kruskal-Wallis test and Tukey test at P < 0.05. Sealapex demonstrated significant differences in the average of filling debris area/canal among the 3 thirds. This group revealed that apical third showed more debris than the both cervical and middle third (P < 0.0001). Endofill presented significantly more filling debris than Sealapex in the cervical third (P < 0.05). In the middle (P = 0.12) and apical third (P = 0.10), there were no differences amongst groups. Debris was left in all canal thirds, regardless of the retreatment technique. The greatest differences between techniques and sealers were found in the cervical third. Copyright © 2012 Wiley Periodicals, Inc.

  19. Paludification and Forest Retreat in Northern Oceanic Environments

    PubMed Central

    CRAWFORD, R. M. M.; JEFFREE, C. E.; REES, W. G.

    2003-01-01

    Examination of temperature variations over the past century for Europe and the Arctic from northern Norway to Siberia suggests that variations in the North Atlantic Oscillation are associated with an increase in oceanicity in certain maritime regions. A southward depression of the treeline in favour of wet heaths, bogs and wetland tundra communities is also observed in northern oceanic environments. The physiological basis for this change in ecological succession from forest to bog is discussed in relation to the long‐term effects of flooding on tree survival. The heightened values currently detected in the North Atlantic Oscillation Index, together with rising winter temperatures, and increased rainfall in many areas in northern Europe, presents an increasing risk of paludification with adverse consequences for forest regeneration, particularly in areas with oceanic climates. Climatic warming in oceanic areas may increase the area covered by bogs and, contrary to general expectations, lead to a retreat rather than an advance in the northern limit of the boreal forest. High water‐table levels are not automatically detrimental to forest survival as can be seen in swamp, bottomland and mangrove forests. Consequently, the inhibitory effects of flooding on tree survival and regeneration in northern regions should not be uncritically accepted as merely due to high water levels. Evidence is discussed which suggests that physiological and ecological factors may interact to inhibit forest regeneration in habitats where there is a risk of prolonged winter‐flooding combined with warmer winters and cool moist summers. PMID:12509342

  20. Paludification and forest retreat in northern oceanic environments.

    PubMed

    Crawford, R M M; Jeffree, C E; Rees, W G

    2003-01-01

    Examination of temperature variations over the past century for Europe and the Arctic from northern Norway to Siberia suggests that variations in the North Atlantic Oscillation are associated with an increase in oceanicity in certain maritime regions. A southward depression of the tree line in favour of wet heaths, bogs and wetland tundra communities is also observed in northern oceanic environments. The physiological basis for this change in ecological succession from forest to bog is discussed in relation to the long-term effects of flooding on tree survival. The heightened values currently detected in the North Atlantic Oscillation Index, together with rising winter temperatures, and increased rainfall in many areas in northern Europe, presents an increasing risk of paludification with adverse consequences for forest regeneration, particularly in areas with oceanic climates. Climatic warming in oceanic areas may increase the area covered by bogs and, contrary to general expectations, lead to a retreat rather than an advance in the northern limit of the boreal forest. High water-table levels are not automatically detrimental to forest survival as can be seen in swamp, bottom land and mangrove forests. Consequently, the inhibitory effects of flooding on tree survival and regeneration in northern regions should not be uncritically accepted as merely due to high water levels. Evidence is discussed which suggests that physiological and ecological factors may interact to inhibit forest regeneration in habitats where there is a risk of prolonged winter-flooding combined with warmer winters and cool moist summers.

  1. In Review (Geology): Alpine Landscape Evolution Dominated by Cirque Retreat

    NASA Technical Reports Server (NTRS)

    Oskin, Michael; Burbank, Doug

    2005-01-01

    Despite the abundance in alpine terrain of glacially dissected landscapes, the magnitude and geometry of glacial erosion can rarely be defined. In the eastern Kyrgyz Range, a widespread unconformity exhumed as a geomorphic surface provides a regional datum with which to calibrate erosion. As tectonically driven surface uplift has progressively pushed this surface into the zone of ice accumulation, glacial erosion has overprinted the landscape. With as little as 500 m of incision into rocks underlying the unconformity, distinctive glacial valleys display their deepest incision adjacent to cirque headwalls. The expansion of north-facing glacial cirques at the expense of south-facing valleys has driven the drainage divide southwards at rates up to 2 to 3 times the rate of valley incision. Existing ice-flux-based glacial erosion rules incompletely model expansion of glacial valleys via cirque retreat into the low-gradient unconformity remnants. Local processes that either directly sap cirque headwalls or inhibit erosion down-glacier appear to control, at least initially, alpine landscape evolution.

  2. Retreatment of Chronic Hepatitis C Infection with Telaprevir : Turkey Experience.

    PubMed

    Pekgöz, M; Gürel, S; Kiyici, M; Gülten, M; Dolar, E; Nak, S G

    2016-03-01

    Patients with genotype 1 chronic hepatitis C virus (HCV) who do not have a sustained virologic response to therapy with peginterferon alfa and ribavirin have a low likelihood of success with retreatment. Voluntary patients aged 18 and older with genotype-1 chronic HCV and with no exclusion criteria were -included. Treatment was organized as following: telaprevir was administered at a dose of 750 mg every 8 hours ; Peg-IFN α-2a was administered at a dose of 180 mcg per week and ribavirin was -administered at a dose of 1000-1200 mg per day. HCV-RNA levels were measured before treatment, at 4, 12, 24 weeks of treatment, after treatment and after 24 weeks of treatment. Sustained virologic response was defined as undetectable HCV-RNA after 24 weeks of treatment. Sustained virologic response was obtained in 37 patients (74%). Breakthrough (BT) or early relapse was seen in 6 patients (12%) in total. Treatment had to be discontinued because of treatment related adverse events in 7 patients (14%). Triple combination therapy including telaprevir is significantly better than classical Peg-IFN α and ribavirin therapy in patients with chronic hepatitis-C infection. © Acta Gastro-Enterologica Belgica.

  3. The 20th Annual Prostate Cancer Foundation Scientific Retreat report.

    PubMed

    Miyahira, Andrea K; Simons, Jonathan W; Soule, Howard R

    2014-06-01

    The 20th Annual Prostate Cancer Foundation (PCF) Scientific Retreat was held from October 24 to 26, 2013, in National Harbor, Maryland. This event is held annually for the purpose of convening a diverse group of leading experimental and clinical researchers from academia, industry, and government to present and discuss critical and emerging topics relevant to prostate cancer (PCa) biology, and the diagnosis, prognosis, and treatment of PCa patients, with a focus on results that will lend to treatments for the most life-threatening stages of this disease. The themes that were highlighted at this year's event included: (i) mechanisms of PCa initiation and progression: cellular origins, neurons and neuroendocrine PCa, long non-coding RNAs, epigenetics, tumor cell metabolism, tumor-immune interactions, and novel molecular mechanisms; (ii) advancements in precision medicine strategies and predictive biomarkers of progression, survival, and drug sensitivities, including the analysis of circulating tumor cells and cell-free tumor DNA-new methods for liquid biopsies; (iii) new treatments including epigenomic therapy and immunotherapy, discovery of new treatment targets, and defining and targeting mechanisms of resistance to androgen-axis therapeutics; and (iv) new experimental and clinical epidemiology methods and techniques, including PCa population studies using patho-epidemiology.

  4. Semantics versus statistics in the retreat from locative overgeneralization errors.

    PubMed

    Ambridge, Ben; Pine, Julian M; Rowland, Caroline F

    2012-05-01

    The present study investigated how children learn that some verbs may appear in the figure-locative but not the ground-locative construction (e.g., Lisa poured water into the cup; *Lisa poured the cup with water), with some showing the opposite pattern (e.g., *Bart filled water into the cup; Bart filled the cup with water), and others appearing in both (Lisa sprayed water onto the flowers; Lisa sprayed the flowers with water). Grammatical acceptability judgments were obtained for the use of each of 142 locative verbs (60 for children) in each sentence type. Overall, and for each age group individually, the judgment data were best explained by a model that included ratings of the extent to which each verb exhibits both the broad- and narrow-range semantic properties of the figure- and ground-locative constructions (relating mainly to manner and end-state respectively; Pinker, 1989) and the statistical-learning measure of overall verb frequency (entrenchment; Braine & Brooks, 1995). A second statistical-learning measure, frequency in each of the two locative constructions (pre-emption; Goldberg, 1995), was found to have no additional dissociable effect. We conclude by drawing together various theoretical proposals to arrive at a possible account of how semantics and statistics interact in the retreat from overgeneralization.

  5. Oceanic forcing and terminus retreat at east Greenland's tidewater glaciers

    NASA Astrophysics Data System (ADS)

    Cowton, Tom; Sole, Andrew; Nienow, Peter; Slater, Donald; Wilton, David; Hanna, Edward

    2017-04-01

    The role of oceanic forcing in the retreat of Greenland's tidewater outlet glaciers remains equivocal, in part due to the difficulty of quantifying how this forcing varies over time and between glaciers. Using plume modelling, we demonstrate that the strength of buoyancy-driven circulation in fjords is highly sensitive to the glacier grounding line depth and runoff discharge, allowing a simple parameterisation for oceanic forcing based on up-fjord oceanic heat transport. In conjunction with time series of glacier runoff and shelf water temperature, we use this parameterisation to elucidate controls on the terminus position of 10 outlet glaciers in east Greenland over a 20-year period. We find that up to 70 % of terminus position variability is explained by modelled oceanic forcing, while comparably strong correlations are also obtained between glacier length and runoff and shelf water temperature. Our findings indicate that despite the complexity of tidewater glacier behaviour and current limitations in understanding of calving front processes, over multi-year time scales a significant proportion of terminus position change can be explained as a simple function of key environmental variables.

  6. Extinction and ecological retreat in a community of primates

    SciTech Connect

    Crowley, B. E.; Godfrey, L. R.; Guilderson, T. P.; Zermeno, P.; Koch, P. L.; Dominy, N. J.

    2012-05-23

    The lemurs of Madagascar represent a prodigious adaptive radiation. At least 17 species ranging from 11 to 160 kg have become extinct during the past 2000 years. The effect of this loss on contemporary lemurs is unknown. The concept of competitive release favours the expansion of living species into vacant niches. Alternatively, factors that triggered the extinction of some species could have also reduced community-wide niche breadth. Here, we use radiocarbon and stable isotope data to examine temporal shifts in the niches of extant lemur species following the extinction of eight large-bodied species. We focus on southwestern Madagascar and report profound isotopic shifts, both from the time when now-extinct lemurs abounded and from the time immediately following their decline to the present. Unexpectedly, the past environments exploited by lemurs were drier than the protected (albeit often degraded) riparian habitats assumed to be ideal for lemurs today. Neither competitive release nor niche contraction can explain these observed trends. We develop an alternative hypothesis: ecological retreat, which suggests that factors surrounding extinction may force surviving species into marginal or previously unfilled niches.

  7. Will present day glacier retreat increase volcanic activity? Stress induced by recent glacier retreat and its effect on magmatism at the Vatnajökull ice cap, Iceland

    NASA Astrophysics Data System (ADS)

    Pagli, Carolina; Sigmundsson, Freysteinn

    2008-05-01

    Global warming causes retreat of ice caps and ice sheets. Can melting glaciers trigger increased volcanic activity? Since 1890 the largest ice cap of Iceland, Vatnajökull, with an area of ~8000 km2, has been continuously retreating losing about 10% of its mass during last century. Present-day uplift around the ice cap is as high as 25 mm/yr. We evaluate interactions between ongoing glacio-isostasy and current changes to mantle melting and crustal stresses at volcanoes underneath Vatnajökull. The modeling indicates that a substantial volume of new magma, ~0.014 km3/yr, is produced under Vatnajökull in response to current ice thinning. Ice retreat also induces significant stress changes in the elastic crust that may contribute to high seismicity, unusual focal mechanisms, and unusual magma movements in NW-Vatnajökull.

  8. The retreat of multiculturalism in the liberal state: theory and policy.

    PubMed

    Joppke, Christian

    2004-06-01

    This article discusses a recent retreat of multiculturalism in the liberal state. This retreat has occurred both at the level of theory and policy. With the help of some recent liberal critiques of multiculturalism, the first part maps out some shortcomings of the notion of minority integration through cultural recognition, particularly with respect to immigrants. The second part discusses a retreat from multiculturalism policies in three states that had been prominently committed to them: Australia, the Netherlands, and Britain. This practical retreat of multiculturalism is due to a variety of factors, their importance differing across cases: the chronic lack of public support for multiculturalism policies; inherent deficits and failures of multiculturalism policies, especially in socio-economic respect; and a new assertiveness of the liberal state to impose liberal principles.

  9. Four-decade record of pervasive grounding line retreat along the Bellingshausen margin of West Antarctica

    NASA Astrophysics Data System (ADS)

    Christie, Frazer D. W.; Bingham, Robert G.; Gourmelen, Noel; Tett, Simon F. B.; Muto, Atsuhiro

    2016-06-01

    Changes to the grounding line, where grounded ice starts to float, can be used as a remotely sensed measure of ice-sheet susceptibility to ocean-forced dynamic thinning. Constraining this susceptibility is vital for predicting Antarctica's contribution to rising sea levels. We use Landsat imagery to monitor grounding line movement over four decades along the Bellingshausen margin of West Antarctica, an area little monitored despite potential for future ice losses. We show that ~65% of the grounding line retreated from 1990 to 2015, with pervasive and accelerating retreat in regions of fast ice flow and/or thinning ice shelves. Venable Ice Shelf confounds expectations in that, despite extensive thinning, its grounding line has undergone negligible retreat. We present evidence that the ice shelf is currently pinned to a sub-ice topographic high which, if breached, could facilitate ice retreat into a significant inland basin, analogous to nearby Pine Island Glacier.

  10. The St. Ignatius Jesuit Retreat and Training Centre: Cultivating Ecological Awareness and Connection with the Earth

    ERIC Educational Resources Information Center

    Groen, Janet

    2017-01-01

    This chapter focuses on the role of religiously based spirituality in cultivating environmental awareness and citizenship by examining an adult environmental education program offered at the Ignatius Jesuit Centre, a religious retreat center in Guelph, Canada.

  11. Contributions of a retreat weekend to the healing and coping of cancer patients' relatives.

    PubMed

    Arnaert, Antonia; Gabos, Theresa; Ballenas, Vincent; Rutledge, Robert D H

    2010-02-01

    Relatives play a key role in the daily support and care of cancer patients. This role, however, can negatively affect relatives physically, psychologically, emotionally, and spiritually, challenging their health and well-being. Consequently, this could inhibit relatives' abilities to continue in their roles as caregivers. Although various studies have examined different interventions for the relatives of cancer patients, no formal research has been published on the role that retreat weekends play in their cancer journeys. In this qualitative study we used semistructured interviews to explore the experiences of 8 relatives who attended a "Skills for Healing Retreat Weekend" in Ontario, Canada. The findings indicate that the retreat, in bringing people together to partake in discussions and activities, fostered a sense of community among the participants. The retreat also had enduring effects, contributing to relatives' ongoing processes of healing as well as providing them with strategies for coping in their roles as caregivers.

  12. Multi-decadal retreat of Novaya Zemlya outlet glaciers, in response to climatic forcing

    NASA Astrophysics Data System (ADS)

    Carr, Rachel; Bell, Heather

    2016-04-01

    Arctic ice masses have rapidly lost ice from the mid-1990s, through a combination of negative surface mass balance and accelerated ice discharge from marine-terminating outlet glaciers. In the past decade, substantial mass deficits have been identified on Novaya Zemlya (NVZ), Russian High Arctic, and its outlet glaciers have retreated dramatically, likely due to declining sea ice concentrations. However, little is known about longer-term glacier behaviour on NVZ, and its potential impact on overall mass balance. Here we greatly extend the available record of retreat and assess multi-decadal glacier response to forcing between 1976 and 2014 using remotely sensed data. Following at least 25 years of gradual recession, retreat rates accelerated substantially from circa. 2000 and again from 2011 onwards. The rate and temporal pattern of retreat were strongly dependant on terminus type: marine-terminating outlets receded an order of magnitude faster than land- or lagoon-terminating glaciers and land-based termini showed limited change in retreat rate over time. Furthermore, retreat was markedly higher on the Barents Sea coast than the Kara Sea. Comparison with forcing data shows that accelerated retreat from 2011 onwards coincided with exceptionally low sea ice concentration and duration between 2011 and 2013. This suggests that sea ice is an important controlling factor, which agrees with shorter-term studies on NVZ. Although air temperature information is more limited on NVZ, data from both meteorological stations and reanalysis highlight 2011 and 2012 as two of the warmest years during the period 1950 to 2014. The limited response of land-terminating outlets suggests that air temperatures do not cause retreat directly, via melting or enhanced basal lubrication, but may have an indirect influence through melting of sea ice or hydro fracture.

  13. Re-Treatment Decisions for Failed Posterior Restorations among Dentists in Kuwait

    PubMed Central

    Alomari, Qasem; Al-Kanderi, Bader; Qudeimat, Muawia; Omar, Ridwaan

    2010-01-01

    Objectives: To compare re-treatment choices for MOD amalgam or resin composite restorations with or without cusp fracture among dentists in Kuwait. Methods: A random sample of 158 dentists completed a questionnaire designed to obtain socio-demographic, educational and work-related information and their choices for re-treatment of four scenarios of failed restorations on lower first molars: 1. MOD amalgam restoration; 2. MOD composite restoration; 3. MOD amalgam restoration with cuspal fracture; 4. MOD composite restoration with cuspal fracture. Re-treatment options were: re-treating with amalgam; re-treating with composite; placing an onlay; or, placing a crown. For the purpose of analysis, responses were dichotomized into re-treatment with a direct or indirect restoration. Results: For cases 1 and 2, most participants chose to re-treat with amalgam restoration and for cases 3 and 4, most chose to place an indirect restoration. In general, an increased tendency towards the indirect option was associated with increased age, being a male and being a specialist. Tendencies to place an indirect restoration did not differ between cases 1 and 2 (P=1.0) or cases 3 and 4 (P=0.317), although the tendency to do so was significantly greater in case 3 than 1 (P=0.000) and case 4 than 2 (P=0.000). Conclusions: The variation noted among dentists regarding their stated choices for re-treating failed posterior restorations appeared to be associated with gender, education and experience factors. A tendency towards indirect restorations was seen when the restoration is associated with a fractured cusp. PMID:20046479

  14. Antarctic marine ice sheet retreat in the Ross Sea during the early Holocene

    NASA Astrophysics Data System (ADS)

    Mckay, R. M.; Golledge, N.; Naish, T.; Maas, S.; Levy, R. H.; Kuhn, G.; Lee, J. I.; Dunbar, G. B.

    2015-12-01

    Geological constraints on the timing of the retreat of the Last Glacial Maximum (LGM) Antarctic Ice Sheets provide critical insights into the processes controlling marine-based ice sheet stability. The over-deepened, seaward shallowing bathymetry of Antarctica's continental shelves is ideally configured to promote past, and potentially future, marine ice-sheet instability. The retreat history of the LGM ice sheet in the Ross Sea region is primarily constrained by C-14 ages on coastal beach ridges and relict penguin colonies along the Transantarctic Mountain front in the Western Ross Sea. Although these terrestrial sites offer more reliable dates than imprecise C-14 chronologies derived from bulk marine sediments, they may reflect retreat of local piedmont glaciers derived from East Antarctic outlet glaciers rather than representing the timing of retreat of the ice sheet in the central Ross Embayment. We present a sedimentary facies succession and foraminifera-based C-14 chronology from a core collected beneath the Ross Ice Shelf via a hot water drill access hole used for the ANDRILL Coulman High site survey. The site is to the east of Ross Island and distal from the coast, and yields a minimum age for glacial retreat that is approximately 1000 yrs earlier than suggested by coastal records along the nearby Victoria Land coast. We examine the implications of this constraint on the timing of ice sheet retreat in the context of model simulations and new multi-beam bathymetry data acquired in the Western Ross Sea. On the basis of these data we hypothesize that marine-based ice sheet retreat was triggered by oceanic forcings along most of the Pacific Ocean coastline of Antarctica simultaneously, but continued retreat in the Ross Sea occurred primarily as a consequence of marine ice sheet instability.

  15. Reliable Refuge: Two Sky Island Scorpion Species Select Larger, Thermally Stable Retreat Sites.

    PubMed

    Becker, Jamie E; Brown, Christopher A

    2016-01-01

    Sky island scorpions shelter under rocks and other surface debris, but, as with other scorpions, it is unclear whether these species select retreat sites randomly. Furthermore, little is known about the thermal preferences of scorpions, and no research has been done to identify whether reproductive condition might influence retreat site selection. The objectives were to (1) identify physical or thermal characteristics for retreat sites occupied by two sky island scorpions (Vaejovis cashi Graham 2007 and V. electrum Hughes 2011) and those not occupied; (2) determine whether retreat site selection differs between the two study species; and (3) identify whether thermal selection differs between species and between gravid and non-gravid females of the same species. Within each scorpion's habitat, maximum dimensions of rocks along a transect line were measured and compared to occupied rocks to determine whether retreat site selection occurred randomly. Temperature loggers were placed under a subset of occupied and unoccupied rocks for 48 hours to compare the thermal characteristics of these rocks. Thermal gradient trials were conducted before parturition and after dispersal of young in order to identify whether gravidity influences thermal preference. Vaejovis cashi and V. electrum both selected larger retreat sites that had more stable thermal profiles. Neither species appeared to have thermal preferences influenced by reproductive condition. However, while thermal selection did not differ among non-gravid individuals, gravid V. electrum selected warmer temperatures than its gravid congener. Sky island scorpions appear to select large retreat sites to maintain thermal stability, although biotic factors (e.g., competition) could also be involved in this choice. Future studies should focus on identifying the various biotic or abiotic factors that could influence retreat site selection in scorpions, as well as determining whether reproductive condition affects thermal

  16. The 13th Annual Aurora Biomed Ion Channel Retreat: Three Days of Research, Technology, and Networking.

    PubMed

    Magee, Kaylee E A; Stanwood, Shawna R

    2016-03-01

    The 13th Annual Ion Channel Retreat was held by Aurora Biomed in Vancouver, Canada from July 7 to 9, 2015. The meeting showcased prominent current research including cardiac safety and pharmacology; ion channel structure, function and engineering; transporters and ion pumps; screening technologies; ion channels as disease targets; alcohol, tobacco, and ion channels; and ion channels as pain targets. This report summarizes the work presented at the retreat.

  17. Reliable Refuge: Two Sky Island Scorpion Species Select Larger, Thermally Stable Retreat Sites

    PubMed Central

    Becker, Jamie E.; Brown, Christopher A.

    2016-01-01

    Sky island scorpions shelter under rocks and other surface debris, but, as with other scorpions, it is unclear whether these species select retreat sites randomly. Furthermore, little is known about the thermal preferences of scorpions, and no research has been done to identify whether reproductive condition might influence retreat site selection. The objectives were to (1) identify physical or thermal characteristics for retreat sites occupied by two sky island scorpions (Vaejovis cashi Graham 2007 and V. electrum Hughes 2011) and those not occupied; (2) determine whether retreat site selection differs between the two study species; and (3) identify whether thermal selection differs between species and between gravid and non-gravid females of the same species. Within each scorpion’s habitat, maximum dimensions of rocks along a transect line were measured and compared to occupied rocks to determine whether retreat site selection occurred randomly. Temperature loggers were placed under a subset of occupied and unoccupied rocks for 48 hours to compare the thermal characteristics of these rocks. Thermal gradient trials were conducted before parturition and after dispersal of young in order to identify whether gravidity influences thermal preference. Vaejovis cashi and V. electrum both selected larger retreat sites that had more stable thermal profiles. Neither species appeared to have thermal preferences influenced by reproductive condition. However, while thermal selection did not differ among non-gravid individuals, gravid V. electrum selected warmer temperatures than its gravid congener. Sky island scorpions appear to select large retreat sites to maintain thermal stability, although biotic factors (e.g., competition) could also be involved in this choice. Future studies should focus on identifying the various biotic or abiotic factors that could influence retreat site selection in scorpions, as well as determining whether reproductive condition affects thermal

  18. Endodontic Re-Treatment of Maxillary Second Molar with Two Separate Palatal Roots: A Case Report

    PubMed Central

    Ghoddusi, Jamileh; Mesgarani, Abbas; Gharagozloo, Salman

    2008-01-01

    Maxillary second molar with two palatal roots is a rare dental anatomy. The diagnosis and treatment of exceeded root may create challenge for clinicians. The authors discuss the retreatment of a maxillary second molar in which exceeded root was undiagnosed in previous treatment. The case report underlines the importance of complete knowledge about root canal morphology which achieved by careful clinical and radiographic examination. In retreatment procedures clinicians should consider missed canals. PMID:24146676

  19. Using Survival Analysis to Identify Risk Factors for Treatment Interruption among New and Retreatment Tuberculosis Patients in Kenya.

    PubMed

    Masini, Enos O; Mansour, Omar; Speer, Clare E; Addona, Vittorio; Hanson, Christy L; Sitienei, Joseph K; Kipruto, Hillary K; Githiomi, Martin Muhingo; Mungai, Brenda Nyambura

    2016-01-01

    Despite high tuberculosis (TB) treatment success rate, treatment adherence is one of the major obstacles to tuberculosis control in Kenya. Our objective was to identify patient-related factors that were associated with time to TB treatment interruption and the geographic distribution of the risk of treatment interruption by county. Data of new and retreatment patients registered in TIBU, a Kenyan national case-based electronic data recording system, between 2013 and 2014 was obtained. Kaplan-Meier curves and log rank tests were used to assess the adherence patterns. Mixed-effects Cox proportional hazards modeling was used for multivariate analysis. Records from 90,170 patients were included in the study. The cumulative incidence of treatment interruption was 4.5% for new patients, and 8.5% for retreatment patients. The risk of treatment interruption was highest during the intensive phase of treatment. Having previously been lost to follow-up was the greatest independent risk factor for treatment interruption (HR: 4.79 [3.99, 5.75]), followed by being HIV-positive not on ART (HR: 1.96 [1.70, 2.26]) and TB relapse (HR: 1.70 [1.44, 2.00]). Male and underweight patients had high risks of treatment interruption (HR: 1.46 [1.35, 1.58]; 1.11 [1.03, 1.20], respectively). High rates of treatment interruption were observed in counties in the central part of Kenya while counties in the northeast had the lowest risk of treatment interruption. A better understanding of treatment interruption risk factors is necessary to improve adherence to treatment. Interventions should focus on patients during the intensive phase, patients who have previously been lost to follow-up, and promotion of integrated TB and HIV services among public and private facilities.

  20. A regional approach for modeling cliff retreat rate: The Makhteshim Country, Israel

    NASA Astrophysics Data System (ADS)

    Finzi, Yaron; Harlev, Noam

    2016-10-01

    Cliff retreat rate significantly affect the evolution of landforms and cliff stability. Cliff retreat studies also provide intriguing clues regarding past geomorphic conditions and environmental changes. We hereby present a model to calculate cliff retreat rate based on spatial data of cliff structure and morphology. The model is applied to numerous cliffs in the arid Makhteshim Country, Israel, and results are calibrated using published rates of two local cliffs. The calculated retreat rates confirm previous assertions that the crater cliffs are receding very slowly, but reveal that the rates vary significantly along the cliffs (1-18 cm ky- 1). Results also provide first estimates of retreat rates of other major cliffs in the region including fast retreat rates at the Sede Zin cliff (300-600 cm ky- 1). The proposed model provides a robust analysis to account for local cliff-talus morphology and yields rate estimates representative of current conditions rather than a long-term (geologic) average rate. Results presented constitute important new insights into regional geomorphic processes and on the stability of specific cliff sections within the study area.

  1. Ofatumumab retreatment and maintenance in fludarabine-refractory chronic lymphocytic leukaemia patients.

    PubMed

    Österborg, Anders; Wierda, William G; Mayer, Jiří; Hess, Georg; Hillmen, Peter; Schetelig, Johannes; Schuh, Anna; Smolej, Lukáš; Beck, Christian; Dreyfus, Brigitte; Hellman, Andrzej; Kozlowski, Piotr; Pfreundschuh, Michael; Rizzi, Rita; Spacek, Martin; Phillips, Jennifer L; Gupta, Ira V; Williams, Vanessa; Jewell, Roxanne C; Nebot, Noelia; Lisby, Steen; Dyer, Martin J S

    2015-07-01

    There are limited data on retreatment with monoclonal antibodies (mAb) in patients with chronic lymphocytic leukaemia (CLL). In a pivotal study, ofatumumab (human anti-CD20 mAb) monotherapy demonstrated a 47% objective response rate (ORR) in fludarabine refractory CLL patients. From this study, a subset of 29 patients who had at least stable disease and then progressed were retreated with eight weekly ofatumumab infusions (induction treatment period), followed by monthly infusions for up to 2 years (maintenance treatment period). The ORR after 8 weeks of induction retreatment was 45% and 24% had continued disease control after maintenance at 52 weeks. Efficacy and safety of the retreated patients were compared with their initial results in the pivotal study. Response duration was 24.1 months vs. 6.8 months; time to next therapy was 14.8 months vs. 12.3 months; and progression-free survival was 7.4 months vs. 7.9 months (medians). Upon retreatment, 72% had infusion reactions, mostly Grade 1-2. Three patients had fatal infections. In summary, ofatumumab retreatment and maintenance therapy was feasible in patients with heavily pretreated CLL and appeared to result in more durable disease control than initial ofatumumab treatment in this subset of patients who may have a more favourable disease profile.

  2. Recent acceleration in coastal cliff retreat rates on the south coast of Great Britain.

    PubMed

    Hurst, Martin D; Rood, Dylan H; Ellis, Michael A; Anderson, Robert S; Dornbusch, Uwe

    2016-11-22

    Rising sea levels and increased storminess are expected to accelerate the erosion of soft-cliff coastlines, threatening coastal infrastructure and livelihoods. To develop predictive models of future coastal change we need fundamentally to know how rapidly coasts have been eroding in the past, and to understand the driving mechanisms of coastal change. Direct observations of cliff retreat rarely extend beyond 150 y, during which humans have significantly modified the coastal system. Cliff retreat rates are unknown in prior centuries and millennia. In this study, we derived retreat rates of chalk cliffs on the south coast of Great Britain over millennial time scales by coupling high-precision cosmogenic radionuclide geochronology and rigorous numerical modeling. Measured (10)Be concentrations on rocky coastal platforms were compared with simulations of coastal evolution using a Monte Carlo approach to determine the most likely history of cliff retreat. The (10)Be concentrations are consistent with retreat rates of chalk cliffs that were relatively slow (2-6 cm⋅y(-1)) until a few hundred years ago. Historical observations reveal that retreat rates have subsequently accelerated by an order of magnitude (22-32 cm⋅y(-1)). We suggest that acceleration is the result of thinning of cliff-front beaches, exacerbated by regional storminess and anthropogenic modification of the coast.

  3. Recent acceleration in coastal cliff retreat rates on the south coast of Great Britain

    NASA Astrophysics Data System (ADS)

    Hurst, Martin D.; Rood, Dylan H.; Ellis, Michael A.; Anderson, Robert S.; Dornbusch, Uwe

    2016-11-01

    Rising sea levels and increased storminess are expected to accelerate the erosion of soft-cliff coastlines, threatening coastal infrastructure and livelihoods. To develop predictive models of future coastal change we need fundamentally to know how rapidly coasts have been eroding in the past, and to understand the driving mechanisms of coastal change. Direct observations of cliff retreat rarely extend beyond 150 y, during which humans have significantly modified the coastal system. Cliff retreat rates are unknown in prior centuries and millennia. In this study, we derived retreat rates of chalk cliffs on the south coast of Great Britain over millennial time scales by coupling high-precision cosmogenic radionuclide geochronology and rigorous numerical modeling. Measured 10Be concentrations on rocky coastal platforms were compared with simulations of coastal evolution using a Monte Carlo approach to determine the most likely history of cliff retreat. The 10Be concentrations are consistent with retreat rates of chalk cliffs that were relatively slow (2-6 cmṡy-1) until a few hundred years ago. Historical observations reveal that retreat rates have subsequently accelerated by an order of magnitude (22-32 cmṡy-1). We suggest that acceleration is the result of thinning of cliff-front beaches, exacerbated by regional storminess and anthropogenic modification of the coast.

  4. Greenland ice sheet retreat history in the northeast Baffin Bay based on high-resolution bathymetry

    NASA Astrophysics Data System (ADS)

    Slabon, Patricia; Dorschel, Boris; Jokat, Wilfried; Myklebust, Reidun; Hebbeln, Dierk; Gebhardt, Catalina

    2016-12-01

    New swath-bathymetric data acquired in 2010 and 2015 indicate a variety of glacial landforms in cross-shelf troughs of the Melville Bay (northeast Baffin Bay). These landforms reveal that, at their maximum extent, ice streams in the troughs crossed the shelf all the way to the shelf edge. Moraines, grounding-zone wedges (GZWs) and subglacial till lobes on the continental shelf define a pattern of variable ice stream retreat in the individual troughs. On the outer shelf, in the northern cross-shelf trough, ice-stream retreat was slow compared to more episodic retreat in the central (at least one stabilization on the outer shelf) and southern cross-shelf trough (re-advances at the shelf edge and fast retreat thereafter). Large GZWs on the mid-to inner shelf of the troughs indicate periods of grounding-zone stabilization. According to glacial landforms, the final retreat across the inner shelf (before 8.41 ka BP) was episodic to slow. Furthermore, evidence has been found for localized ice domes with minor ice-streams on inter-trough banks. The glacial landforms in Melville Bay, thus, indicate the varying and discontinuous ice sheet retreat history across the Northwest Greenland continental shelf.

  5. Hot rocks or no hot rocks: overnight retreat availability and selection by a diurnal lizard.

    PubMed

    Sabo, John L

    2003-08-01

    I used radio telemetry to determine the effects of substrate size and composition on overnight retreat site selection by western fence lizards (Sceloporus occidentalis). In watersheds of northern California (USA), these lizards occupy two habitat types differing in substrate characteristics: rocky cobble bars found in the dry, active channels of rivers and grassy upland meadows. Rocky substrates, found almost exclusively on cobble bars, provided warmer potential retreat sites than all available retreat sites on meadows during the first 5 h of inactivity. Only cobble and sand substrates provided retreats with temperatures within the preferred daily active range (32-36 degrees C) during the inactive period for these lizards (1900-0900 hours). Females on a cobble bar used rocks as retreats on >90% of nights during the breeding season whereas females on a meadow used wood (>70% of nights) and burrows (>25% of nights). In contrast to females, cobble bar males used rocks significantly less frequently (<70%) and slept in the open air significantly more frequently (25% vs. <1%). Cobble bar females further, showed a significant preference for cobbles 15 cm thick, whereas the rocks used by males did not differ significantly in thickness from those measured in randomly placed transects. Rocks 15 cm thick were the warmest retreats commonly available on this habitat type. Thus, thermal microenvironments available to and chosen by gravid female lizards differ considerably between river and non-river habitats.

  6. Retreat space and human visitor density moderate undesirable behavior in petting zoo animals.

    PubMed

    Anderson, Ursula S; Benne, Marcie; Bloomsmith, Mollie A; Maple, Terry L

    2002-01-01

    This study focused on the relationship between nonhuman animal behavior and envi-ronment- specifically, between the undesirable behavior exhibited by domestic pet-ting zoo animals in the presence of humans and the spatial design of the petting zoo environment. A spatial feature of a petting zoo referred to as a retreat space was ma-nipulated so that it affected the animals' opportunity for individual control over inter-action with humans. Three conditions were tested: no retreat space, semi-retreat space, and a full-retreat space. The subjects of this study were 5 African pygmy goats (Capra hircus) and 2 Romanov sheep (Ovis aries). Investigators used a focal sam-pling technique to analyze approximately 27 hr of behavioral data collected. The data were analyzed using multiple linear regression methods. The findings suggest that the full-retreat design beneficially moderated both sheep and goat behavior: Undesirable behaviors were lowest in the full-retreat condition. This study provides information that may improve human-animal interactions in a petting zoo setting and may in-crease animal well-being through exhibit design and management techniques.

  7. Recent acceleration in coastal cliff retreat rates on the south coast of Great Britain

    PubMed Central

    Ellis, Michael A.; Anderson, Robert S.; Dornbusch, Uwe

    2016-01-01

    Rising sea levels and increased storminess are expected to accelerate the erosion of soft-cliff coastlines, threatening coastal infrastructure and livelihoods. To develop predictive models of future coastal change we need fundamentally to know how rapidly coasts have been eroding in the past, and to understand the driving mechanisms of coastal change. Direct observations of cliff retreat rarely extend beyond 150 y, during which humans have significantly modified the coastal system. Cliff retreat rates are unknown in prior centuries and millennia. In this study, we derived retreat rates of chalk cliffs on the south coast of Great Britain over millennial time scales by coupling high-precision cosmogenic radionuclide geochronology and rigorous numerical modeling. Measured 10Be concentrations on rocky coastal platforms were compared with simulations of coastal evolution using a Monte Carlo approach to determine the most likely history of cliff retreat. The 10Be concentrations are consistent with retreat rates of chalk cliffs that were relatively slow (2–6 cm⋅y−1) until a few hundred years ago. Historical observations reveal that retreat rates have subsequently accelerated by an order of magnitude (22–32 cm⋅y−1). We suggest that acceleration is the result of thinning of cliff-front beaches, exacerbated by regional storminess and anthropogenic modification of the coast. PMID:27821750

  8. The effect of a power-law mantle viscosity on trench retreat rate

    NASA Astrophysics Data System (ADS)

    Holt, Adam F.; Becker, Thorsten W.

    2017-01-01

    The subduction of lithospheric plates is partitioned between subducting plate motion and lateral slab migration (i.e. trench retreat and advance). We use 3-D, dynamic models of subduction to address the role of a power-law mantle viscosity on subduction dynamics and, in particular, rates of trench retreat. For all numerical models tested, we find that a power-law rheology results in reduced rates of trench retreat, and elevated slab dip angles, relative to the equivalent isoviscous mantle model. We analyse the asthenospheric pressure distribution and the style of mantle flow, which exhibits only limited variability as a function of mantle rheology, in order to compute estimates of the mantle forces associated with subduction. The inclusion of a power-law rheology reduces the mantle shear force (which resists subducting plate motion) to a greater degree than it reduces the dynamic pressure gradient across the slab (which resists trench retreat). Therefore, the inclusion of a power-law mantle rheology favours a shift towards a subduction mode with a reduced trench retreat component, typically a relative reduction of order 25 per cent in our 3-D models. We suggest that this mechanism may be of importance for reducing the high trench retreat rates observed in many previous models to levels more in line with the average subduction partitioning observed on Earth at present (i.e. trench velocity ≤ plate velocity), for most absolute plate motion reference frames.

  9. Glacier retreat in New Zealand during the Younger Dryas stadial.

    PubMed

    Kaplan, Michael R; Schaefer, Joerg M; Denton, George H; Barrell, David J A; Chinn, Trevor J H; Putnam, Aaron E; Andersen, Bjørn G; Finkel, Robert C; Schwartz, Roseanne; Doughty, Alice M

    2010-09-09

    Millennial-scale cold reversals in the high latitudes of both hemispheres interrupted the last transition from full glacial to interglacial climate conditions. The presence of the Younger Dryas stadial (approximately 12.9 to approximately 11.7 kyr ago) is established throughout much of the Northern Hemisphere, but the global timing, nature and extent of the event are not well established. Evidence in mid to low latitudes of the Southern Hemisphere, in particular, has remained perplexing. The debate has in part focused on the behaviour of mountain glaciers in New Zealand, where previous research has found equivocal evidence for the precise timing of increased or reduced ice extent. The interhemispheric behaviour of the climate system during the Younger Dryas thus remains an open question, fundamentally limiting our ability to formulate realistic models of global climate dynamics for this time period. Here we show that New Zealand's glaciers retreated after approximately 13 kyr bp, at the onset of the Younger Dryas, and in general over the subsequent approximately 1.5-kyr period. Our evidence is based on detailed landform mapping, a high-precision (10)Be chronology and reconstruction of former ice extents and snow lines from well-preserved cirque moraines. Our late-glacial glacier chronology matches climatic trends in Antarctica, Southern Ocean behaviour and variations in atmospheric CO(2). The evidence points to a distinct warming of the southern mid-latitude atmosphere during the Younger Dryas and a close coupling between New Zealand's cryosphere and southern high-latitude climate. These findings support the hypothesis that extensive winter sea ice and curtailed meridional ocean overturning in the North Atlantic led to a strong interhemispheric thermal gradient during late-glacial times, in turn leading to increased upwelling and CO(2) release from the Southern Ocean, thereby triggering Southern Hemisphere warming during the northern Younger Dryas.

  10. Irradiation and Bevacizumab in High-Grade Glioma Retreatment Settings

    SciTech Connect

    Niyazi, Maximilian; Ganswindt, Ute; Schwarz, Silke Birgit; Kreth, Friedrich-Wilhelm; Tonn, Joerg-Christian; Geisler, Julia; Fougere, Christian la; Ertl, Lorenz; Linn, Jennifer; Siefert, Axel; Belka, Claus

    2012-01-01

    Purpose: Reirradiation is a treatment option for recurrent high-grade glioma with proven but limited effectiveness. Therapies directed against vascular endothelial growth factor have been shown to exert certain efficacy in combination with chemotherapy and have been safely tested in combination with radiotherapy in a small cohort of patients. To study the feasibility of reirradiation combined with bevacizumab treatment, the toxicity and treatment outcomes of this approach were analyzed retrospectively. Patients and Methods: After previous treatment with standard radiotherapy (with or without temozolomide) patients with recurrent malignant glioma received bevacizumab (10 mg/kg intravenous) on Day 1 and Day 15 during radiotherapy. Maintenance therapy was selected based on individual considerations, and mainly bevacizumab-containing regimens were chosen. Patients received 36 Gy in 18 fractions. Results: The data of the medical charts of the 30 patients were analyzed retrospectively. All were irradiated in a single institution and received either bevacizumab (n = 20), no additional substance (n = 7), or temozolomide (n = 3). Reirradiation was tolerated well, regardless of the added drug. In 1 patient treated with bevacizumab, a wound dehiscence occurred. Overall survival was significantly better in patients receiving bevacizumab (p = 0.03, log-rank test). In a multivariate proportional hazards Cox model, bevacizumab, Karnovsky performance status, and World Health Organization grade at relapse turned out to be the most important predictors for overall survival. Conclusion: Reirradiation with bevacizumab is a feasible and effective treatment for patients with recurrent high-grade gliomas. A randomized trial is warranted to finally answer the question whether bevacizumab adds substantial benefit to a radiotherapeutic retreatment setting.

  11. Why is there no Universal Law for Rock Wall Retreat?

    NASA Astrophysics Data System (ADS)

    Krautblatter, Michael; Moore, Jeffrey

    2016-04-01

    Comparing studies of rock slope erosion and soil slope erosion, we find no governing equation similar to the universal soil loss equation for rock slopes. Rock masses in contact with the atmosphere are affected by a suite of physical, chemical and biological processes which degrade intact rock, creating new fractures and extending existing flaws. Complex feedbacks must be explored between changing slope boundary conditions, stress redistribution and fracturing, and weathering by external mechanisms. Rock slope systems are distinguished from soil slope systems by the fundamental nonlinear properties of rock masses. Rock masses represent discontinuous, inhomogeneous, anisotropic, and nonlinearly elastic materials, and contain a record of millions of years of thermal, hydrological, mechanical and chemical (THMC) processes. The origin and evolution of rock mass strength over time can significantly affect bedrock erodibility and engineering performance, the study of which represents a major chance and challenge for the geoscience community. The imprint of THMC processes on rock properties begins with the geological genesis of rocks; however, a significant degree of material behaviour evolves coincidently with the exhumation and evolution of topography. Thus, fracture generation has been investigated as the result of the environmental stress history in geology and geomorphology, partly modulated by incision and topographic stress evolution. Resultant fracture patterns control the degree of discontinuity heterogeneity, anisotropy, and nonlinear mechanical behaviour over millions of years. Here we discuss important novel conceptual approaches to temporally and spatially decipher nonlinear effects on rock slope erosion including incision-related topographic stresses, rock fatigue, paraglacial and paracratering effects etc. and how they could contribute to a more uniform understanding of rockwall retreat.

  12. Outcomes of Holmium Laser Enucleation of the Prostate in the Re-Treatment Setting.

    PubMed

    Marien, Tracy; Kadihasanoglu, Mustafa; Tangpaitoon, Teerayut; York, Nadya; Blackburne, Andrew T; Abdul-Muhsin, Haidar; Borofsky, Michael S; Krambeck, Amy E; Humphreys, Mitchell R; Lingeman, James E; Miller, Nicole L

    2017-06-01

    Holmium laser enucleation of the prostate can also be applied in the re-treatment setting when other benign prostatic hyperplasia therapies fail. We compared outcomes in men who underwent holmium laser enucleation of the prostate in the primary vs the re-treatment setting. We retrospectively reviewed the records of 2,242 patients who underwent holmium laser enucleation of the prostate at a total of 4 academic hospitals between 2003 and 2015. Patient demographics, and operative and perioperative outcomes were compared between re-treatment and primary holmium laser enucleation of the prostate. Of the 360 of 2,242 men (16%) who underwent re-treatment holmium laser enucleation of the prostate the procedure was done for residual urinary symptoms in 71%. The most common primary procedure was transurethral resection of the prostate in 42% of cases. Mean time between prior benign prostatic hyperplasia surgery and re-treatment was 68 months (range 1 to 444). There were no significant differences in age, prostate size, AUA (American Urological Association) symptom score or average flow rate between the cohorts. Perioperatively, re-treatment holmium laser enucleation of the prostate was associated with significantly shorter operative time, reduced blood loss, lower specimen weight and shorter length of stay. The AUA symptom score improved in both groups, although it remained higher in men who underwent re-treatment (6.5 vs 5.0, p <0.001). The likelihood of clot retention (4.7% vs 1.8%, p = 0.01) and urethral stricture (3.3% vs 1.5%, p = 0.043) was slightly higher in the re-treatment group. Immediate perioperative outcomes of holmium laser enucleation of the prostate performed in the re-treatment setting were no different from those in the primary setting. While re-treatment was associated with an increased likelihood of clot retention, urethral stricture and higher AUA symptom score, these minimal differences must be considered against the overall favorable symptom

  13. Focusing on Main Street's Problems from Secluded Laboratory Retreats

    ERIC Educational Resources Information Center

    Kushner, Lawrence M.

    1973-01-01

    A report on the National Bureau of Standards is presented. It provides national measurement standards for some 40 physical quantities related through the laws of physics to the basic six - length, time, mass, temperature, electric current, and luminous intensity. (DF)

  14. Focusing on Main Street's Problems from Secluded Laboratory Retreats

    ERIC Educational Resources Information Center

    Kushner, Lawrence M.

    1973-01-01

    A report on the National Bureau of Standards is presented. It provides national measurement standards for some 40 physical quantities related through the laws of physics to the basic six - length, time, mass, temperature, electric current, and luminous intensity. (DF)

  15. National assessment of shoreline change part 4: historical coastal cliff retreat along the California coast

    USGS Publications Warehouse

    Hapke, Cheryl J.; Reid, David

    2007-01-01

    Coastal cliff retreat, the landward migration of the cliff face, is a chronic problem along many rocky coastlines in the United States. As coastal populations continue to grow and community infrastructures are threatened by erosion, there is increased demand for accurate information regarding trends and rates of coastal cliff retreat. There is also a need for a comprehensive analysis of cliff retreat that is consistent from one coastal region to another. To meet these national needs, the U.S. Geological Survey is conducting an analysis of historical coastal cliff retreat along open-ocean rocky coastlines of the conterminous United States and parts of Hawaii, Alaska, and the Great Lakes. One purpose of this work is to develop standard repeatable methods for mapping and analyzing coastal cliff retreat so that periodic updates of coastal erosion can be made nationally that are systematic and internally consistent. This report on the California Coast is an accompaniment to a report on long-term sandy shoreline change for California. This report summarizes the methods of analysis, interprets the results, and provides explanations regarding long-term rates of cliff retreat. Neither detailed background information on the National Assessment of Shoreline Change Project nor detailed descriptions of the geology and geomorphology of the California coastline are presented in this report. The reader is referred to the shoreline change report (Hapke et al., 2006) for this type of background information. Cliff retreat evaluations are based on comparing one historical cliff edge digitized from maps, with a recent cliff edge interpreted from lidar (Light Detection and Ranging) topographic surveys. The historical cliff edges are from a period ranging from 1920-1930, whereas the lidar cliff edges are from either 1998 or 2002. Long-term (~70-year) rates of retreat are calculated using the two cliff edges. The rates of retreat presented in this report represent conditions from the 1930

  16. Deriving mechanisms and thresholds for cliff retreat in soft-rock cliffs under changing climates: Rapidly retreating cliffs of the Suffolk coast, UK

    NASA Astrophysics Data System (ADS)

    Brooks, S. M.; Spencer, T.; Boreham, S.

    2012-06-01

    Understanding changing thresholds and mechanisms for retreat in soft rock cliffs is important under changing climates. This can be achieved through combining detailed field observation, long-term process and morphological monitoring and numerical modelling. The cliffs of the Suffolk coast, southern North Sea have exhibited long-term (1883-2010) recession rates of 3.5 m a- 1, rising to 4.7 m a- 1 in the period 1993-2010. Annual to biannual ground survey data, and the application of GIS techniques to digitised records of changing shoreline position from historic maps and aerial photography, reveal considerable decadal-scale variations in cliff recession, within which are nested inter-annual fluctuations in rates of retreat. Archival datasets on significant periods of onshore winds and their interaction with high water levels (including the incidence of storm surges) and rainstorm events are used to determine thresholds for cliff base erosion and its propagation upwards through the cliff profile. In addition, the ‘GEO-Slope' dynamic coupled hydrology-stability model is used to establish thresholds for cliff face failures driven by variations in rainfall inputs. Retreat mechanisms are complex, governed by cliff geology, both as a primary control on suction loss and through its interaction with basal marine conditions. The study allows a general model of cliff retreat for soft rock cliffs to be put forward, whereby a resistant basal platform is overlain by more erodible, weakly and moderately cemented sands and gravels. In this model, the varying balance between marine and terrestrial forcing factors are reflected in low (< 4 m a- 1), intermediate (4-7 m a- 1) and high (> 7 m a- 1) modes of cliff retreat.

  17. Hasty retreat of glaciers in the Palena province of Chile

    NASA Astrophysics Data System (ADS)

    Paul, F.; Mölg, N.; Bolch, T.

    2013-12-01

    Mapping glacier extent from optical satellite data has become a most efficient tool to create or update glacier inventories and determine glacier changes over time. A most valuable archive in this regard is the nearly 30-year time series of Landsat Thematic Mapper (TM) data that is freely available (already orthorectified) for most regions in the world from the USGS. One region with a most dramatic glacier shrinkage and a missing systematic assessment of changes, is the Palena province in Chile, south of Puerto Montt. A major bottleneck for accurate determination of glacier changes in this region is related to the huge amounts of snow falling in this very maritime region, hiding the perimeter of glaciers throughout the year. Consequently, we found only three years with Landsat scenes that can be used to map glacier extent through time. We here present the results of a glacier change analysis from six Landsat scenes (path-rows 232-89/90) acquired in 1985, 2000 and 2011 covering the Palena district in Chile. Clean glacier ice was mapped automatically with a standard technique (TM3/TM band ratio) and manual editing was applied to remove wrongly classified lakes and to add debris-covered glacier parts. The digital elevation model (DEM) from SRTM was used to derive drainage divides, determine glacier specific topographic parameters, and analyse the area changes in regard to topography. The scene from 2000 has the best snow conditions and was used to eliminate seasonal snow in the other two scenes by digital combination of the binary glacier masks. The observed changes show a huge spatial variability with a strong dependence on elevation and glacier hypsometry. While small mountain glaciers at high elevations and steep slopes show virtually no change over the 26-year period, ice at low elevations from large valley glaciers shows a dramatic decline (area and thickness loss). Some glaciers retreated more than 3 km over this time period or even disappeared completely

  18. Small scale tests on the progressive retreat of soil slopes

    NASA Astrophysics Data System (ADS)

    Voulgari, Chrysoula; Utili, Stefano; Castellanza, Riccardo

    2015-04-01

    In this paper, the influence due to the presence of cracks on the morphologic evolution of natural cliffs subject to progressive retreat induced by weathering is investigated through small scale laboratory tests. Weathering turns hard rocks into soft rocks that maintain the structure of the intact rocks, but are characterised by higher void ratios and reduced bond strengths; soft rocks are transformed into granular soils generally called residual soils. A number of landslides develop in slopes due to weathering which results in the progressive retrogression of the slope face and the further degradation within the weathering zone. Cracks, that are widely present, can be a result of weathering and they can cause a significant decrease in their stability, as they provide preferential flow channels which increase the soil permeability and decrease the soil strength. The geological models employed until now are mainly empirical. Several researchers have tried to study the stability of slopes through experimental procedures. Centrifuge modelling is widely used to investigate the failure of slopes. Small scale tests are also an important approach, in order to study the behaviour of a slope under certain conditions, such as the existence of water, as they allow the observation of the infiltration processes, the movement of the weathering front, deformation and failure. However, the deformation response of a slope subject to weathering is not yet thoroughly clarified. In this work, a set of experiments were conducted to investigate weathering induced successive landslides. Weathering was applied to the slope model by wetting the slope crest through a rainfall simulator device. The moisture content of the soil during the tests was monitored by soil moisture sensors that were buried inside the slope model. High resolution cameras were recording the behaviour of the slope model. GeoPIV was used to analyse the frames and obtain the deformations of the slope model during the

  19. Retreatment of Recurrent Internal Carotid-Posterior Communicating Artery Aneurysm after Coil Embolization.

    PubMed

    Toyota, Shingo; Taki, Takuyu; Wakayama, Akatsuki; Yoshimine, Toshiki

    2015-01-01

    Internal carotid-posterior communicating artery (IC-PC) aneurysms account for more than 20% of all intracranial aneurysms. As a result of the increase in coiling, there has also been an increase in recurrent IC-PC aneurysms after coiling. We present our experience of 10 recurrent IC-PC aneurysms after coiling that were retreated using surgical or endovascular techniques in order to discuss the choice of treatment and the points of clipping without removal of coils. From 2007 to 2014, 10 recurrent IC-PC aneurysms after coiling were retreated. When the previous frames covered the aneurysms all around or almost around except a part of the neck, coiling was chosen. In other cases, clipping was chosen. Clipping was attempted without removal of coils when it was technically feasible. Among the 10 IC-PC aneurysms retreated, 3 were retreated with coiling and 7 were retreated with clipping. In all three cases retreated with coiling, almost complete occlusion was accomplished. In the seven cases retreated with clipping, coil extrusion was observed during surgery in six cases. In most of them, it was necessary to dissect strong adhesions around the coiled aneurysms and to utilize temporary occlusion of the internal carotid artery. In all seven cases, neck clipping was accomplished without the removal of coils. There were no neurological complications in any cases. The management of recurrent lesions of embolized IC-PC aneurysms requires appropriate choice of treatment using both coiling and clipping. Clipping, especially without the removal of coils, plays an important role in safe treatment.

  20. Modeling Antarctic Ice Sheet retreat in warm climates: a historical perspective.

    NASA Astrophysics Data System (ADS)

    Pollard, D.; Deconto, R. M.; Gasson, E.

    2016-12-01

    Early modeling of Antarctic Ice Sheet size vs. climate focused on asymmetry between retreat and growth, with much greater warming needed to cause retreat from full ice cover, due to Height Mass Balance Feedback and albedo feedback. This led to a long-standing model-data conflict, with models needing 1000 to2000 ppmv atmospheric CO2 to produce retreat from full size, vs. proxy data of large ice fluctuations despite much lower CO2 since the Miocene.Subsequent modeling with marine ice physics found that the West Antarctic Ice Sheet could undergo repeated warm-period collapses with realistic past forcing. However, that yields only 3 to 7 m equivalent sea-level rise above modern, compared to 10 to 20 m or more suggested by some geologic data. Large subglacial basins in East Antarctica could be vulnerable to the same processes,but did not retreat in most models due to narrower and shallower sills.After recent modifications, some ice sheet models were able to produce warm-period collapse of major East Antarctic basins, with sea-level rise of up to 15 m. The modifications are (i) hydrofracturing by surface melt, and structural failure of ice cliffs, or (ii) numerical treatment at the grounding line. In these models, large retreat occurs both for past warmintervals, and also for future business-as-usual scenarios.Some interpretations of data in the late Oligocene and Miocene suggest yet larger fluctuations, between 50 to 100% of modern Antarctic size. That would require surface-melt driven retreat of some terrestrial East Antarctic ice, despite the hysteresis issue raised above. A recent study using a coupled climate-ice sheet model found that with a finer climate gridand more frequent coupling exchange, substantial retreat of terrestrial Antarctica can occur with 500 to 840 ppmv CO2, much lower than in earlier models. This will allow meaningful interactions between modeling and deeper-time geologic interpretations since the late Oligocene.

  1. Loitering of the retreating sea ice edge in the Arctic Seas

    PubMed Central

    Ermold, Wendy

    2015-01-01

    Abstract Each year, the arctic sea ice edge retreats from its winter maximum extent through the Seasonal Ice Zone (SIZ) to its summer minimum extent. On some days, this retreat happens at a rapid pace, while on other days, parts of the pan‐arctic ice edge hardly move for periods of days up to 1.5 weeks. We term this stationary behavior “ice edge loitering,” and identify areas that are more prone to loitering than others. Generally, about 20–25% of the SIZ area experiences loitering, most often only one time at any one location during the retreat season, but sometimes two or more times. The main mechanism controlling loitering is an interaction between surface winds and warm sea surface temperatures in areas from which the ice has already retreated. When retreat happens early enough to allow atmospheric warming of this open water, winds that force ice floes into this water cause melting. Thus, while individual ice floes are moving, the ice edge as a whole appears to loiter. The time scale of loitering is then naturally tied to the synoptic time scale of wind forcing. Perhaps surprisingly, the area of loitering in the arctic seas has not changed over the past 25 years, even as the SIZ area has grown. This is because rapid ice retreat happens most commonly late in the summer, when atmospheric warming of open water is weak. We speculate that loitering may have profound effects on both physical and biological conditions at the ice edge during the retreat season. PMID:27812435

  2. Retreatment of Recurrent Internal Carotid-Posterior Communicating Artery Aneurysm after Coil Embolization

    PubMed Central

    TOYOTA, Shingo; TAKI, Takuyu; WAKAYAMA, Akatsuki; YOSHIMINE, Toshiki

    2015-01-01

    Internal carotid-posterior communicating artery (IC-PC) aneurysms account for more than 20% of all intracranial aneurysms. As a result of the increase in coiling, there has also been an increase in recurrent IC-PC aneurysms after coiling. We present our experience of 10 recurrent IC-PC aneurysms after coiling that were retreated using surgical or endovascular techniques in order to discuss the choice of treatment and the points of clipping without removal of coils. From 2007 to 2014, 10 recurrent IC-PC aneurysms after coiling were retreated. When the previous frames covered the aneurysms all around or almost around except a part of the neck, coiling was chosen. In other cases, clipping was chosen. Clipping was attempted without removal of coils when it was technically feasible. Among the 10 IC-PC aneurysms retreated, 3 were retreated with coiling and 7 were retreated with clipping. In all three cases retreated with coiling, almost complete occlusion was accomplished. In the seven cases retreated with clipping, coil extrusion was observed during surgery in six cases. In most of them, it was necessary to dissect strong adhesions around the coiled aneurysms and to utilize temporary occlusion of the internal carotid artery. In all seven cases, neck clipping was accomplished without the removal of coils. There were no neurological complications in any cases. The management of recurrent lesions of embolized IC-PC aneurysms requires appropriate choice of treatment using both coiling and clipping. Clipping, especially without the removal of coils, plays an important role in safe treatment. PMID:26437796

  3. Early results of systematic drug susceptibility testing in pulmonary tuberculosis retreatment cases in Cameroon

    PubMed Central

    2012-01-01

    Background The number of pulmonary tuberculosis (PTB) patients reported with resistance to first-line anti-tuberculosis drugs after a standardized retreatment regimen in Cameroon is increasing. Hence, the National Tuberculosis Control Program (NTP) implemented, in one of the ten Regions of the country, a pilot programme aimed at performing routine drug susceptibility testing (DST) for previously treated PTB cases. The objectives of the programme were to evaluate the feasibility of monitoring drug resistance among retreatment cases under programme conditions and to measure the presence and magnitude of anti-TB drug resistance in order to inform NTP policies. Findings This retrospective cohort study was conducted in the Littoral Region of Cameroon in 2009. It included all sputum smear positive (SM+) PTB cases registered for retreatment. TB cases were identified and classified according to World Health Organization (WHO) recommendations for national TB programs. Bacterial susceptibility testing to first-line anti-TB drugs was performed using standard culture methods. In 2009, 5,668 TB cases were reported in the Littoral Region, of which 438 (7.7%) were SM + PTB retreatment cases. DST results were available for 216 (49.4%) patients. Twenty six patients (12%) harbored multi-drug resistant (MDR) strains. Positive treatment outcome rates were particularly low in retreatment patients with MDR-TB (46.2%; 95% CI: 27.1-66.3). Thirteen MDR-TB patients were treated using a standardized MDR treatment regimen. Delivery of laboratory results took on average 17 (12-26) weeks. Conclusions WHO-recommended routine DST in retreatment patients seems feasible in Cameroon. However, coverage needs to be improved through better management. Moreover, diagnostic delay should be shortened by introducing more rapid diagnostic tools. The high risk of MDR in standard regimen failure cases virtually rules out the standard retreatment regimen for such patients without prior DST. PMID:22436423

  4. Benthic Trophic Interactions in an Antarctic Shallow Water Ecosystem Affected by Recent Glacier Retreat.

    PubMed

    Pasotti, Francesca; Saravia, Leonardo Ariel; De Troch, Marleen; Tarantelli, Maria Soledad; Sahade, Ricardo; Vanreusel, Ann

    2015-01-01

    The western Antarctic Peninsula is experiencing strong environmental changes as a consequence of ongoing regional warming. Glaciers in the area are retreating rapidly and increased sediment-laden meltwater runoff threatens the benthic biodiversity at shallow depths. We identified three sites with a distinct glacier-retreat related history and different levels of glacial influence in the inner part of Potter Cove (King George Island, South Shetland Islands), a fjord-like embayment impacted since the 1950s by a tidewater glacier retreat. We compared the soft sediment meio- and macrofauna isotopic niche widths (δ13C and δ15N stable isotope analysis) at the three sites to investigate possible glacier retreat-related influences on benthic trophic interactions. The isotopic niches were locally shaped by the different degrees of glacier retreat-related disturbance within the Cove. Wider isotopic niche widths were found at the site that has become ice-free most recently, and narrower niches at the older ice-free sites. At an intermediate state of glacier retreat-related disturbance (e.g. via ice-growler scouring) species with different strategies could settle. The site at the earliest stage of post-retreat development was characterized by an assemblage with lower trophic redundancy. Generally, the isotopic niche widths increased with increasing size spectra of organisms within the community, excepting the youngest assemblage, where the pioneer colonizer meiofauna size class displayed the highest isotopic niche width. Meiofauna at all sites generally occupied positions in the isotopic space that suggested a detrital-pool food source and/or the presence of predatory taxa. In general ice scour and glacial impact appeared to play a two-fold role within the Cove: i) either stimulating trophic diversity by allowing continuous re-colonization of meiofaunal species or, ii) over time driving the benthic assemblages into a more compact trophic structure with increased

  5. Benthic Trophic Interactions in an Antarctic Shallow Water Ecosystem Affected by Recent Glacier Retreat

    PubMed Central

    Pasotti, Francesca; Saravia, Leonardo Ariel; De Troch, Marleen; Tarantelli, Maria Soledad; Sahade, Ricardo; Vanreusel, Ann

    2015-01-01

    The western Antarctic Peninsula is experiencing strong environmental changes as a consequence of ongoing regional warming. Glaciers in the area are retreating rapidly and increased sediment-laden meltwater runoff threatens the benthic biodiversity at shallow depths. We identified three sites with a distinct glacier-retreat related history and different levels of glacial influence in the inner part of Potter Cove (King George Island, South Shetland Islands), a fjord-like embayment impacted since the 1950s by a tidewater glacier retreat. We compared the soft sediment meio- and macrofauna isotopic niche widths (δ13C and δ15N stable isotope analysis) at the three sites to investigate possible glacier retreat-related influences on benthic trophic interactions. The isotopic niches were locally shaped by the different degrees of glacier retreat-related disturbance within the Cove. Wider isotopic niche widths were found at the site that has become ice-free most recently, and narrower niches at the older ice-free sites. At an intermediate state of glacier retreat-related disturbance (e.g. via ice-growler scouring) species with different strategies could settle. The site at the earliest stage of post-retreat development was characterized by an assemblage with lower trophic redundancy. Generally, the isotopic niche widths increased with increasing size spectra of organisms within the community, excepting the youngest assemblage, where the pioneer colonizer meiofauna size class displayed the highest isotopic niche width. Meiofauna at all sites generally occupied positions in the isotopic space that suggested a detrital-pool food source and/or the presence of predatory taxa. In general ice scour and glacial impact appeared to play a two-fold role within the Cove: i) either stimulating trophic diversity by allowing continuous re-colonization of meiofaunal species or, ii) over time driving the benthic assemblages into a more compact trophic structure with increased

  6. Map showing coastal cliff retreat rates along the Big Sur coast, Monterey and San Luis Obispo Counties, California

    USGS Publications Warehouse

    Hapke, Cheryl J.; Green, Krystal R.

    2004-01-01

    The average coastal cliff retreat rate along the Big Sur coast is 18 ? 6 cm/yr as measured over a 52-year time period. The erosion reference features measured as the cliff edge include the well-defined cliff edges common to marine terraces, slight breaks in the slope defining the upper edge of the active lower slope, and the road grade. Cliff erosion and retreat are focused in isolated erosion hotspots that account for most of the calculated average retreat.

  7. Little Ice Age advance and retreat of Glaciar Jorge Montt, Chilean Patagonia

    NASA Astrophysics Data System (ADS)

    Rivera, A.; Koppes, M.; Bravo, C.; Aravena, J. C.

    2012-03-01

    Glaciar Jorge Montt (48°20' S/73°30' W), one of the main tidewater glaciers of the Southern Patagonian Icefield (SPI), has experienced the greatest terminal retreat observed in Patagonia during the past century, with a recession of 19.5 km between 1898 and 2011. This retreat has revealed trees laying subglacially until 2003. These trees were dated using radiocarbon, yielding burial ages between 460 and 250 cal yrs BP. The presence of old growth forest during those dates indicates that Glaciar Jorge Montt was upvalley of its present position before the commonly recognized Little Ice Age (LIA) period in Patagonia. The post-LIA retreat was most likely triggered by climatically induced changes during the 20th century; however, Glaciar Jorge Montt has responded more dramatically than its neighbours. The retreat of Jorge Montt opened a 19.5 km long fjord since 1898, which reaches depths in excess of 390 m. The bathymetry is well correlated with glacier retreat rates, suggesting that dynamic responses of the glacier are at least partially connected to near buoyancy conditions at the ice front, resulting in high calving fluxes, accelerating thinning rates and rapid ice velocities.

  8. Coupled ice shelf-ocean modeling and complex grounding line retreat from a seabed ridge

    NASA Astrophysics Data System (ADS)

    De Rydt, J.; Gudmundsson, G. H.

    2016-05-01

    Recent observations and modeling work have shown a complex mechanical coupling between Antarctica's floating ice shelves and the adjacent grounded ice sheet. A prime example is Pine Island Glacier, West Antarctica, which has a strong negative mass balance caused by a recent increase in ocean-induced melting of its ice shelf. The mass loss coincides with the retreat of the grounding line from a seabed ridge, on which it was at least partly grounded until the 1970s. At present, it is unclear what has caused the onset of this retreat and how feedback mechanisms between the ocean and ice shelf geometry have influenced the ice dynamics. To address these questions, we present the first results from an offline coupling between a state-of-the-art shallow-ice flow model with grounding line resolving capabilities and a three-dimensional ocean general circulation model with a static implementation of the ice shelf. A series of idealized experiments simulate the retreat from a seabed ridge in response to changes in the ocean forcing, and we show that the retreat becomes irreversible after 20 years of warm ocean conditions. A comparison to experiments with a simple depth-dependent melt rate parameterization demonstrates that such parameterizations are unable to capture the details of the retreat process, and they overestimate mass loss by more than 40% over a 50 year timescale.

  9. Coupled ice shelf-ocean modeling and complex grounding line retreat for Pine Island Glacier

    NASA Astrophysics Data System (ADS)

    De Rydt, Jan; Gudmundsson, Hilmar

    2016-04-01

    Recent observations and modeling work have shown a complex mechanical coupling between Antarctica's floating ice shelves and the adjacent grounded ice sheet. A prime example is Pine Island Glacier, West Antarctica, which has a strong negative mass balance caused by a recent increase in ocean-induced melting of its ice shelf. The mass loss coincides with the retreat of the grounding line from a seabed ridge, on which it was at least partly grounded until the 1970s. At present, it is unclear what has caused the onset of this retreat, and how feedback mechanisms between the ocean and iceshelf geometry have influenced the ice dynamics. To address these questions, we present results from an offline coupling between a state-of-the-art shallow-ice flow model with grounding line resolving capabilities, and a three-dimensional ocean general circulation model with a static implementation of the ice shelf. A series of idealized experiments simulate the retreat from a seabed ridge in response to changes in the ocean forcing, and we show that the retreat becomes irreversible after 20 years of warm ocean conditions. A comparison to experiments with a simple depth-dependent meltrate parameterisation demonstrates that such parameterizations are unable to capture the details of the retreat process, and they overestimate mass loss by more than 40% over a 50-year timescale.

  10. Increased capture of magma in the crust promoted by ice-cap retreat in Iceland

    NASA Astrophysics Data System (ADS)

    Hooper, Andrew; Ófeigsson, Benedikt; Sigmundsson, Freysteinn; Lund, Björn; Einarsson, Páll; Geirsson, Halldór; Sturkell, Erik

    2011-11-01

    Climate warming at the end of the last glaciation caused ice caps on Icelandic volcanoes to retreat. Removal of surface ice load is thought to have decreased pressures in the underlying mantle, triggering decompression melting, enhanced magma generation and increased volcanic activity. Present-day climate change could have the same effect, although there may be a time lag of hundreds of years between magma generation and eruption. However, in addition to increased magma generation, pressure changes associated with ice retreat should also alter the capacity for storing magma within the crust. Here we use a numerical model to evaluate the effect of the current decrease in ice load on magma storage in the crust at the Kverkfjöll volcanic system, located partially beneath Iceland's largest ice cap. We compare the model results with radar and global positioning system measurements of surface displacement and changes in crustal stress between 2007 and 2008, during the intrusion of a deep dyke at Upptyppingar. We find that although the main component of stress recorded during dyke intrusion relates to plate extension, another component of stress is consistent with the stress field caused by the retreating ice cap. We conclude that the retreating ice cap led to enhanced capture of magma within the crust. We suggest that ice-cap retreat can promote magma storage, rather than eruption, at least in the short term.

  11. A prospective, international phase 2 study of bortezomib retreatment in patients with relapsed multiple myeloma.

    PubMed

    Petrucci, Maria T; Giraldo, Pilar; Corradini, Paolo; Teixeira, Adriana; Dimopoulos, Meletios A; Blau, Igor W; Drach, Johannes; Angermund, Ralf; Allietta, Nathalie; Broer, Esther; Mitchell, Vivien; Bladé, Joan

    2013-03-01

    Multiple myeloma (MM) typically follows a relapsing course with many patients requiring multiple therapies. This single-arm phase 2 study prospectively evaluated the efficacy and safety of bortezomib retreatment in MM patients who had relapsed after achieving at least a partial response (≥ PR) to prior bortezomib-based therapy. Patients aged ≥ 18 years, with measurable, secretory MM, who relapsed ≥ 6 months after prior bortezomib treatment were eligible. Patients received up to eight cycles of bortezomib (± dexamethasone). The primary endpoint was best confirmed response at retreatment; secondary endpoints included duration of response (DOR), time to progression (TTP), and safety. Adverse events (AEs) were graded by National Cancer Institute Common Terminology Criteria for Adverse Events version 3.0. A total of 130 patients (median of two prior lines of therapy) were enrolled and received retreatment. At retreatment, 28% and 72% of patients received bortezomib and bortezomib-dexamethasone, respectively. Overall response rate was 40%. In patients who achieved ≥ PR, median DOR and TTP were 6.5 and 8.4 months, respectively. Thrombocytopenia was the most common grade ≥ 3 AE (35%). Forty percent of patients experienced neuropathy events, which improved and resolved in a median of 1.5 and 8.9 months, respectively. In conclusion, bortezomib retreatment was effective and tolerable in relapsed MM patients, with no evidence of cumulative toxicities. © 2013 Blackwell Publishing Ltd.

  12. Post-LGM Retreat History in Ross Sea Reflects Changing Controls on Marine Ice Sheet Behavior

    NASA Astrophysics Data System (ADS)

    Halberstadt, A. R.; Simkins, L. M.; Anderson, J. B.; Prothro, L. O.; Demet, B. P.; Greenwood, S. L.; Yokoyama, Y.

    2016-12-01

    Newly collected high-resolution multibeam swath bathymetry data and sediment cores, combined with two decades of legacy multibeam and seismic data, are used to map glacial landforms, reconstruct paleodrainage and study patterns, timing, and controls on marine-based ice-sheet dynamics in Antarctica's largest drainage basin, the Ross Sea. This paleodrainage reconstruction independently validates recent numerical models that call for significant and dynamic East Antarctic Ice Sheet and West Antarctic Ice Sheet contributions to ice flow in the Ross Sea. Last Glacial Maximum grounded ice reached the continental shelf edge in the eastern but not western Ross Sea. Recessional geomorphic features in the western Ross Sea indicate frequent, small scale grounding line retreat from the outer shelf following an episode of ice shelf collapse. In contrast, well-preserved linear features and large, isolated grounding zone wedges record large scale (tens of kilometers) step-wise grounding line retreat in eastern Ross Sea. Physiography exerted a first-order control on ice behavior, while seafloor geology played an important subsidiary role. Our analysis of retreat patterns further indicates that: (1) initial ice sheet retreat was initiated by a large grounding line embayment in the eastern Ross Sea; (2) retreat was highly variable and asynchronous between troughs; and (3) subglacial meltwater played a role in destabilizing grounding lines in parts of the western Ross Sea.

  13. Outcomes of HIV-infected Patients Treated for Recurrent Tuberculosis with the Standard Retreatment Regimen

    PubMed Central

    McGreevy, Jolion; Juste, Marc Antoine Jean; Severe, Patrice; Collins, Sean; Koenig, Serena; Pape, Jean William; Fitzgerald, Daniel W

    2013-01-01

    SETTING AIDS and tuberculosis center in Port-au-Prince, Haiti. OBJECTIVE To measure the effectiveness of tuberculosis retreatment with the standard regimen (2HRZES/1HRZE/5HRE) in HIV-infected adults. DESIGN Cohort study. RESULTS Of 1,318 HIV-infected patients with access to antiretroviral therapy following World Health Organization guidelines, 56 were diagnosed with recurrent pulmonary tuberculosis and retreated with the standard regimen. Ten patients (18%) died during retreatment, 3 patients (5%) defaulted, and 2 patients (4%) failed. Forty-one patients (73%) had a good retreatment outcome (cure, treatment completed). Of these, 8 patients (20%) died during follow-up, 5 patients (12%) were lost, and 5 patients (12%) had a second recurrence of tuberculosis. Only 26 (46%) of the 56 patients remained alive, in-care, and TB-free after a median of 36 months follow-up. CONCLUSION HIV-infected patients treated for recurrent tuberculosis with the standard retreatment regimen have a high mortality and poor long-term outcomes. PMID:22507948

  14. Evaluation of a team-building retreat to promote nursing faculty cohesion and job satisfaction.

    PubMed

    Birx, Ellen; Lasala, Kathleen B; Wagstaff, Mark

    2011-01-01

    With the growing global shortage of nursing faculty, there is increased need to develop and evaluate strategies to promote nursing faculty job satisfaction. Using quantitative and qualitative research methods, a team-building faculty retreat including challenge course activities was evaluated to determine its effects on group cohesion and job satisfaction. Mean Job in General scores for the sample (n = 29) at the start of the study were comparable with national norms for employees with graduate degrees. There were statistically significant increases in Job in General scores and group cohesion scores from pretest to posttest on the day of the retreat. However, the positive changes were not maintained at the end of the semester when follow-up data were gathered. Content analysis of the retreat day reflections revealed the following themes: getting to know each other better, seeing commonalities and differences, spending time together, developing trust, and working as a group. Several themes were identified in the end of the semester reflections: getting to know each other, feeling closer as a group, setting a friendlier tone for the semester, and that the retreat was a positive experience. Based on these findings, we recommend the use of a faculty retreat with challenge course activities to promote nursing faculty cohesion and job satisfaction. However, follow-up activities are recommended to maintain positive results over time.

  15. Orthograde endodontic retreatment of teeth with individual cast posts: report of two cases.

    PubMed

    Ramić, Bojana; Stojanac, Igor; Premović, Milica; Drobac, Milan; Petrović, Ljubomir

    2012-01-01

    The failure of primary endodontic treatment is manifested by various clinical symptoms following endodontic therapy or, more frequently, by the development of chronic inflammatory process in the apex region without any subjective symptoms. In case of unfavorable outcome of the primary endodontic treatment, orthograde endodontic retreatment is the method of choice for a prolonged therapy. Two female patients, 47 and 44 years old, were presented at the Dental Clinic of Vojvodina for endodontic retreatment of teeth 22, 23 and 13, within the repeated prosthetic restoration. Intraradicular individual cast posts were removed using ultrasonic instruments. Remains of gutta-percha were removed by engine driven rotary re-treatment files, root canals were shaped and cleaned using the crown-down technique, and obturated with gutta-percha and epoxy-resin-based sealer using the lateral compaction technique. When there are metal posts or broken instruments in the root canal, the use of ultrasonic instruments is considered a safe method characterized by negligible tooth substance loss and minimal root damage causing fractures and perforations, and the entire procedure is effective and predictable. Non-surgical orthograde endodontic retreatment, when properly performed in accessible and penetrable root canals, achieves a high cure rate, good and lasting results and eliminates the need for radical procedures, such as apical surgery or tooth extraction. When nonsurgical endodontic retreatment is done, treated teeth must be restored by full coronal coverage as soon as possible, to prevent coronal leakage or fracture.

  16. Knickpoint retreat and landscape evolution of the Amatlán de Cañas half-graben (northern sector of Jalisco Block, western Mexico)

    NASA Astrophysics Data System (ADS)

    Castillo, Miguel; Ferrari, Luca; Muñoz-Salinas, Esperanza

    2017-08-01

    Rivers are known to respond to changes in the rate of rock uplift by propagating knickpoints through the fluvial network. Downstream of knickpoints, river incision increases local relief producing also the steepening of hillslopes. Thus, knickpoints convey information about the amount of rock uplift to which the fluvial system must respond. Because the incisional pulse produced by the rapid rock uplift is recorded in the topography of channels, the analysis of longitudinal profiles can be used for evaluating the response of landscape to tectonic activity. Here we analyse the longitudinal profile of rivers (n = 84) and the river basin topography (n = 72) with the aim of unravelling the evolution of the Amatlán de Cañas half-graben (ACHG), a Plio-Quaternary structure located in the northern sector of the Jalisco Block (west-central Mexico). Our results indicate that two rock uplift pulses formed the footwall of the ACHG. The distance of knickpoint retreat from the fault scarp exhibit a strong correlation with the stream length (R2 = 0.80), highlighting the importance of stream discharge on knickpoint migration. Clustering of high values of relief, river incision and normalised channel steepness index (ksn) around the centre of the footwall confirms that this is the zone of maximum throw. The propagation of knickpoints along Ameca river is producing the degradation of fans and relief rejuvenation. Using compiled data of knickpoint retreat rates of other tectonically active landscapes, it was found that the stream discharge and the timing and rate of rock uplift are together a first order control on the rate of knickpoint recession. This study supports the idea that the understanding of knickpoints is crucial to unravel the evolution of tectonically active landscapes.

  17. Effects of L-Aspartic acid on the step retreat kinetics of calcite

    NASA Astrophysics Data System (ADS)

    Yoshino, Toru; Kagi, Hiroyuki

    2012-01-01

    Effects of L-Aspartic acid (L-Asp) on step retreat kinetics in the dissolution of calcite were investigated. The step retreat velocities under surface-controlled kinetics were determined from in-situ atomic force microscopic observations using an improved flow-through system. Comparison of the present results with those obtained under a mixed kinetics condition revealed that the addition of L-Asp promotes the transport process in the calcite dissolution through acid-base and/or complex forming reactions in the diffusion boundary layer. Additionally, promotion of the acute and obtuse step retreats by the L-Asp additive was observed under surface-controlled kinetics. This report is the first to clarify that L-Asp promotes surface processes in the dissolution of calcite.

  18. Retreat of Glaciar Tyndall, Patagonia, over the last half-century

    NASA Astrophysics Data System (ADS)

    Raymond, Charles; Neumann, Thomas A.; Rignot, Eric; Echelmeyer, Keith; Rivera, Andrés; Casassa, Gino

    We report measurements of ice surface elevation, ice thickness and surface area for Glaciar Tyndall, Patagonia, made in 1999 2002. The measurements, together with previously published observations, show acceleration over the last few decades of the rates of thinning and retreat of the main calving front. The acceleration of shrinkage appears to be driven by a combination of climate and feedback processes, the dominant feedback being increased melting associated with lowering of the glacier surface (elevation feedback). The melting capacity in the main terminus lake is now too small to be a major factor accelerating the retreat. The glacier bed has low slope and remains below the elevation of the lake spillway for >14 km upstream from the 2000 calving front, indicating the potential for extensive retreat under the influence of strong elevation feedback and increasing interaction with the lake as it enlarges.

  19. Antarctic last interglacial isotope peak in response to sea ice retreat not ice-sheet collapse

    PubMed Central

    Holloway, Max D.; Sime, Louise C.; Singarayer, Joy S.; Tindall, Julia C.; Bunch, Pete; Valdes, Paul J.

    2016-01-01

    Several studies have suggested that sea-level rise during the last interglacial implies retreat of the West Antarctic Ice Sheet (WAIS). The prevalent hypothesis is that the retreat coincided with the peak Antarctic temperature and stable water isotope values from 128,000 years ago (128 ka); very early in the last interglacial. Here, by analysing climate model simulations of last interglacial WAIS loss featuring water isotopes, we show instead that the isotopic response to WAIS loss is in opposition to the isotopic evidence at 128 ka. Instead, a reduction in winter sea ice area of 65±7% fully explains the 128 ka ice core evidence. Our finding of a marked retreat of the sea ice at 128 ka demonstrates the sensitivity of Antarctic sea ice extent to climate warming. PMID:27526639

  20. Radioiodine uptake following iodine-131 therapy for Graves' disease: an early indicator of need for retreatment

    SciTech Connect

    Carpentier, W.R.; Gilliland, P.F.; Piziak, V.K.; Petty, F.C.; McConnell, B.G.; Verdonk, C.A.; Ibarra, J.D.; Thompson, J.Q.

    1989-01-01

    Forty-five patients with Graves' disease were studied prospectively to determine if 24-hour I-131 uptake measurements alone or in combination with serum thyroid hormone levels at six weeks would determine the necessity for retreatment of the thyrotoxicosis. All patients with an I-131 uptake greater than 30% at six weeks required retreatment. No patient with an I-131 uptake of less than 15% required retreatment. Patients with uptakes between 15% and 30% were variable. An elevated free thyroxin index at 6 weeks is not helpful to determine which patients will remain thyrotoxic. Patients with a free thyroxin index within the normal range at six weeks can be predicted to be euthyroid by 12 weeks if their 24-hour I-131 uptake is between 15% and 30% and to be hypothyroid if their 24-hour I-131 uptake is below 15%. There was no difference between patient groups treated initially with antithyroid medication and those who were not.

  1. Short-term sea cliff failure events accumulate into long-term cliff retreat signals

    NASA Astrophysics Data System (ADS)

    Limber, Patrick; Palaseanu-Lovejoy, Monica; Danielson, Jeffrey; Barnard, Patrick

    2017-04-01

    Sea cliff retreat is an episodic process, where sudden landslide events punctuate longer periods of relative cliff stability. Understanding sea cliff behavior is key to defining coastal hazard zones or projecting future retreat due to sea level rise (SLR), when present. But, predicting when a particular landslide will occur, or how large it will be, is exceptionally difficult. As a result, rates of sea cliff retreat are often time-averaged over many individual landslides during a given time interval. Time averaging of episodic processes like cliff retreat has several drawbacks, however. For one, the mean erosion or retreat rate can be heavily biased by the time interval over which it is measured, especially over short time scales (e.g. <10-20 years). Another inherent problem of time-averaged rates is the immediate loss of information about the short-term, seemingly random processes (i.e. landslides) that give rise to them. Is a mean long-term (multiple decades or longer) retreat rate caused by the accumulation of a few large landslides, or many smaller landslides? Or, consider the corollary: can observations of landslide size and frequency be used to infer long-term cliff retreat rates? Fortunately the relationship between landslide area and frequency follows a predictable pattern in which landslide frequency (or probability) is a negative power law function of landslide area. Using on landslide frequency-area relationships determined using cliff edges extracted from 18 LiDAR surveys over a 12-year period in California (USA), we developed a simple cellular automata model of probabilistic cliff failure in order to link long-term and short-term cliff behavior. During a model time step, each alongshore cell on the cliff edge has a failure probability primarily determined by 1) a prescribed landslide frequency-area distribution and 2) beach width, so that the failure probability is lessened for wide beaches and vice versa. Beach width at each cell is determined by

  2. Risk assessment of the toxicity of solvents of gutta-percha used in endodontic retreatment.

    PubMed

    Chutich, M J; Kaminski, E J; Miller, D A; Lautenschlager, E P

    1998-04-01

    Three randomly assigned groups of single-canaled extracted teeth obturated with gutta-percha were retreated using controlled application of one of three organic solvents: chloroform, xylene, or halothane. Two additional groups of teeth served as positive and negative controls. Residual volume of solvent expressed through the apical foramen during retreatment was determined by the difference of pretreatment and posttreatment weights of hermetically sealed receptacles attached to the root surface of the teeth. Results indicate that the amount of solvent that has been determined to have leached out through the apical foramen is several orders of magnitude below the permissible toxic dose. Thus, it is proposed that the use of any of the aforementioned solvents used in the retreatment of root canals would pose negligible risk to the patient.

  3. Skillful seasonal forecasts of Arctic sea ice retreat and advance dates in a dynamical forecast system

    NASA Astrophysics Data System (ADS)

    Sigmond, M.; Reader, M. C.; Flato, G. M.; Merryfield, W. J.; Tivy, A.

    2016-12-01

    The need for skillful seasonal forecasts of Arctic sea ice is rapidly increasing. Technology to perform such forecasts with coupled atmosphere-ocean-sea ice systems has only recently become available, with previous skill evaluations mainly limited to area-integrated quantities. Here we show, based on a large set of retrospective ensemble model forecasts, that a dynamical forecast system produces skillful seasonal forecasts of local sea ice retreat and advance dates - variables that are of great interest to a wide range of end users. Advance dates can generally be skillfully predicted at longer lead times ( 5 months on average) than retreat dates ( 3 months). The skill of retreat date forecasts mainly stems from persistence of initial sea ice anomalies, whereas advance date forecasts benefit from longer time scale and more predictable variability in ocean temperatures. These results suggest that further investments in the development of dynamical seasonal forecast systems may result in significant socioeconomic benefits.

  4. High mortality associated with retreatment of tuberculosis in a clinic in Kampala, Uganda: a retrospective study.

    PubMed

    Acuña-Villaorduña, Carlos; Ayakaka, Irene; Dryden-Peterson, Scott; Nakubulwa, Susan; Worodria, William; Reilly, Nancy; Hosford, Jennifer; Fennelly, Kevin P; Okwera, Alphonse; Jones-López, Edward C

    2015-07-01

    The World Health Organization recommends for tuberculosis retreatment a regimen of isoniazid (H), rifampicin (R), ethambutol (E), pyrazinamide (Z), and streptomycin (S) for 2 months, followed by H, R, E, and Z for 1 month and H, R, and E for 5 months. Using data from the National Tuberculosis and Leprosy Program registry, this study determined the long-term outcome under programmatic conditions of patients who were prescribed the retreatment regimen in Kampala, Uganda, between 1997 and 2003. Patients were traced to determine their vital status; 62% (234/377) patients were found dead. Having ≤ 2 treatment courses and not completing retreatment were associated with mortality in adjusted analyses. © The American Society of Tropical Medicine and Hygiene.

  5. Fast retreat of Zachariæ Isstrøm, northeast Greenland.

    PubMed

    Mouginot, J; Rignot, E; Scheuchl, B; Fenty, I; Khazendar, A; Morlighem, M; Buzzi, A; Paden, J

    2015-12-11

    After 8 years of decay of its ice shelf, Zachariæ Isstrøm, a major glacier of northeast Greenland that holds a 0.5-meter sea-level rise equivalent, entered a phase of accelerated retreat in fall 2012. The acceleration rate of its ice velocity tripled, melting of its residual ice shelf and thinning of its grounded portion doubled, and calving is now occurring at its grounding line. Warmer air and ocean temperatures have caused the glacier to detach from a stabilizing sill and retreat rapidly along a downward-sloping, marine-based bed. Its equal-ice-volume neighbor, Nioghalvfjerdsfjorden, is also melting rapidly but retreating slowly along an upward-sloping bed. The destabilization of this marine-based sector will increase sea-level rise from the Greenland Ice Sheet for decades to come.

  6. Antarctic last interglacial isotope peak in response to sea ice retreat not ice-sheet collapse.

    PubMed

    Holloway, Max D; Sime, Louise C; Singarayer, Joy S; Tindall, Julia C; Bunch, Pete; Valdes, Paul J

    2016-08-16

    Several studies have suggested that sea-level rise during the last interglacial implies retreat of the West Antarctic Ice Sheet (WAIS). The prevalent hypothesis is that the retreat coincided with the peak Antarctic temperature and stable water isotope values from 128,000 years ago (128 ka); very early in the last interglacial. Here, by analysing climate model simulations of last interglacial WAIS loss featuring water isotopes, we show instead that the isotopic response to WAIS loss is in opposition to the isotopic evidence at 128 ka. Instead, a reduction in winter sea ice area of 65±7% fully explains the 128 ka ice core evidence. Our finding of a marked retreat of the sea ice at 128 ka demonstrates the sensitivity of Antarctic sea ice extent to climate warming.

  7. The ninth annual Ion Channel Retreat, Vancouver, Canada, June 27-29, 2011.

    PubMed

    Brugger, Saranna; Garate, Marco; Papaianni, Gina; Volnoukhin, Maria; Zhan, Chris; Gill, Sikander; Liang, Sophia; Liang, Dong

    2011-12-01

    Nine years ago Aurora Biomed Inc. (Vancouver, Canada) committed to gathering the brightest minds and the most innovative research companies at one conference. The Ion Channel Retreat provides a podium for scientific discourse spanning a wide range of ion channel disciplines. This conference has consistently provided a venue for people to share knowledge, exchange ideas, and establish partnerships. This conference continues to expand and grow each year, demonstrating the value of such a conference. Attendees at the 2011 Ion Channel retreat presented ion channel research from 12 different countries, representing research groups located on 5 of the 7 continents. Aurora Biomed's 2011 Retreat covered a variety of topics including Ion Channels as Disease Targets, Ion Channels as Pain Targets, TRP-channels, Ion Channel Screening Technologies, Cardiac Function and Pharmacology, Cardiac Safety and Toxicology, and Structure and Function of Ion Channels.

  8. Patellofemoral pain: proximal, distal, and local factors, 2nd International Research Retreat.

    PubMed

    Powers, Christopher M; Bolgla, Lori A; Callaghan, Michael J; Collins, Natalie; Sheehan, Francis T

    2012-06-01

    Patellofemoral pain (PFP) is one of the most common lower extremity conditions seen in orthopaedic practice. The mission of the second International Patellofemoral Pain Research Retreat was to bring together scientists and clinicians from around the world who are conducting research aimed at understanding the factors that contribute to the development and, consequently, the treatment of PFP. The format of the 2.5-day retreat included 2 keynote presentations, interspersed with 6 podium and 4 poster sessions. An important element of the retreat was the development of consensus statements that summarized the state of the research in each of the 4 presentation categories. In this supplement, you will find the consensus documents from the meeting, as well as the keynote addresses, schedule, and platform and poster presentation abstracts.

  9. Influence of solvents on the bond strength of resin sealer to intraradicular dentin after retreatment.

    PubMed

    Palhais, Marcelo; Sousa-Neto, Manoel Damião; Rached-Junior, Fuad Jacob Abi; Amaral, Mariana Carvalho de Andrade; Alfredo, Edson; Miranda, Carlos Eduardo Saraiva; Silva-Sousa, Yara Teresinha Corrêa

    2017-01-26

    This study evaluated the removal of filling material with ProTaper Universal Rotary Retreatment system (PTR) combined with solvents and the influence of solvents on the bond strength (PBS) of sealer to intraradicular dentin after canal reobturation. Roots were endodontically treated and distributed to five groups (n = 12). The control group was not retreated. In the four experimental groups, canals were retreated with PTR alone or in combination with xylol, orange oil, and eucalyptol. After filling material removal, two specimens of each group were analysed by SEM and µCT to verify the presence of filling remnants on root canal walls. The other roots were reobturated and sectioned in 1-mm-thick dentin slices that were subjected to the push-out test. Data were analysed by two-way ANOVA and Tukey's test (α = 0.05). SEM and µCT analysis revealed that all retreatment techniques left filling remnants on canal walls. The control group (3.47 ± 1.21) presented significantly higher (p < 0.05) PBS than the experimental groups. The groups retreated with PTR alone (2.59 ± 0.99) or combined with xylol (2.54 ± 0.77) and orange oil (2.32 ± 0.93) presented similar bond strength (p > 0.05), and differed significantly from the group with eucalyptol (1.89 ± 0.63). The solvents reduced the PBS of the sealer to dentin and no retreatment technique promoted complete removal of filling material.

  10. Effectiveness of traditional meditation retreats: A systematic review and meta-analysis.

    PubMed

    Khoury, Bassam; Knäuper, Bärbel; Schlosser, Marco; Carrière, Kimberly; Chiesa, Alberto

    2017-01-01

    An increasing number of studies are investigating traditional meditation retreats. Very little, however, is known about their effectiveness. To evaluate the effectiveness of meditation retreats on improving psychological outcomes in general population. A systematic review of studies published in journals or as dissertations in PSYCINFO, PUBMED, CINAHL or Web of Science from the first available date until October 22, 2016. A total of 20 papers (21 studies, N=2912) were included. Effect-size estimates of outcomes combined suggested that traditional meditation retreats are moderately effective in pre-post analyses (n=19; Hedge's g=0.45; 95% CI [0.35, 0.54], p<0.00001) and in analyses comparing retreats to controls (n=14; Hedge's g=0.49; 95% CI [0.36, 0.61], p<0.00001). Results were maintained at follow-up. No differences were observed between meditation styles. Results suggested large effects on measures of anxiety, depression and stress, and moderate effects on measures of emotional regulation and quality of life. As to potential mechanisms of actions, results showed large effects on measures of mindfulness and compassion, and moderate effects on measures of acceptance. In addition, changes in mindfulness levels strongly moderated clinical effect sizes. However, heterogeneity was significant among trials, probably due to differences in study designs, types and duration of the retreats and assessed outcomes, limiting therefore the implications of the results. Meditation retreats are moderately to largely effective in reducing depression, anxiety, stress and in ameliorating the quality of life of participants. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. Sub-ice-shelf sediments record history of twentieth-century retreat of Pine Island Glacier.

    PubMed

    Smith, J A; Andersen, T J; Shortt, M; Gaffney, A M; Truffer, M; Stanton, T P; Bindschadler, R; Dutrieux, P; Jenkins, A; Hillenbrand, C-D; Ehrmann, W; Corr, H F J; Farley, N; Crowhurst, S; Vaughan, D G

    2017-01-05

    The West Antarctic Ice Sheet is one of the largest potential sources of rising sea levels. Over the past 40 years, glaciers flowing into the Amundsen Sea sector of the ice sheet have thinned at an accelerating rate, and several numerical models suggest that unstable and irreversible retreat of the grounding line-which marks the boundary between grounded ice and floating ice shelf-is underway. Understanding this recent retreat requires a detailed knowledge of grounding-line history, but the locations of the grounding line before the advent of satellite monitoring in the 1990s are poorly dated. In particular, a history of grounding-line retreat is required to understand the relative roles of contemporaneous ocean-forced change and of ongoing glacier response to an earlier perturbation in driving ice-sheet loss. Here we show that the present thinning and retreat of Pine Island Glacier in West Antarctica is part of a climatically forced trend that was triggered in the 1940s. Our conclusions arise from analysis of sediment cores recovered beneath the floating Pine Island Glacier ice shelf, and constrain the date at which the grounding line retreated from a prominent seafloor ridge. We find that incursion of marine water beyond the crest of this ridge, forming an ocean cavity beneath the ice shelf, occurred in 1945 (±12 years); final ungrounding of the ice shelf from the ridge occurred in 1970 (±4 years). The initial opening of this ocean cavity followed a period of strong warming of West Antarctica, associated with El Niño activity. Thus our results suggest that, even when climate forcing weakened, ice-sheet retreat continued.

  12. Hillslope failure and paraglacial reworking of sediments in response to glacier retreat, Fox Valley, New Zealand.

    NASA Astrophysics Data System (ADS)

    McColl, Samuel T.; Fuller, Ian C.; Anderson, Brian; Tate, Rosie

    2017-04-01

    Climate and glacier fluctuations influence sediment supply to glacier forelands, which in turn influences down-valley hazards to infrastructure and tourism within glacier forelands. At Fox Glacier, one of New Zealand's most iconic and popular glaciers, rapid retreat has initiated a range of hillslope and valley floor responses, that present a cascade of hazards and changes that need to be carefully managed. Fox Glacier has retreated many kilometres historically, with 2.6 km of retreat since the mid-20th century, and a phase of rapid retreat of 50-340 m per year since 2009. To study the system response to past and ongoing glacial retreat at the Fox valley, morphological changes are being observed using time-lapse photography and the annual collection of high-resolution digital elevation models (DEMs) and orthophoto mosaics. The DEMs are being produced using Structure from Motion photogrammetry from UAV/RPAS and helicopter platforms, and are being used, along with manual ground surveying, to produce ground surface change models (DoDs; DEMs of Difference) and sediment budgets for the valley. Results from time-lapse photography and DoDs show that glacial retreat has initiated destabilisation and (mostly chronic) mass movement of surficial glacial sediments on the valley slopes near the glacier terminus. Alluvial fans farther down valley are actively growing, reworking glacial and landslide sediments from tributary catchments. These paraglacial sediments being delivered to the proglacial river from the glacier terminus and alluvial fans are driving aggradation of the valley floor of decimetres to metres per year and maintaining a highly dynamic braid plain. Valley floor changes also include the melting of buried dead ice, which are causing localised subsidence at the carpark and one of the alluvial fans. The unstable slopes and active debris fans, aggrading and highly active river channel, ground subsidence, add to the spectacle but also the hazards of the Fox valley

  13. Forecasting sea cliff retreat in Southern California using process-based models and artificial neural networks

    NASA Astrophysics Data System (ADS)

    Limber, P. W.; Barnard, P.; Erikson, L. H.

    2016-02-01

    Modeling coastal geomorphic change over multi-decadal time and regional spatial scales (i.e. >20 km alongshore) is in high demand due to rising global sea levels and heavily populated coastal zones, but is challenging for several reasons: adequate geomorphic and oceanographic data often does not exist over the entire study area or time period; models can be too computationally expensive; and model uncertainty is high. In the absence of rich datasets and unlimited computer processing power, researchers are forced to leverage existing data, however sparse, and find analytical methods that minimize computation time without sacrificing (too much) model reliability. Machine learning techniques, such as artificial neural networks, can assimilate and efficiently extrapolate geomorphic model behavior over large areas. They can also facilitate ensemble model forecasts over a broad range of parameter space, which is useful when a paucity of observational data inhibits the constraint of model parameters. Here, we assimilate the behavior of two established process-based sea cliff erosion and retreat models into a neural network to forecast the impacts of sea level rise on sea cliff retreat in Southern California ( 400 km) through the 21st century. Using inputs such as historical cliff retreat rates, mean wave power, and whether or not a beach is present, the neural network independently reproduces modeled sea cliff retreat as a function of sea level rise with a high degree of confidence (R2 > 0.9, mean squared error < 0.1 m yr-1). Results will continuously improve as more model scenarios are assimilated into the neural network, and more field data (i.e., cliff composition and rock hardness) becomes available to tune the cliff retreat models. Preliminary results suggest that sea level rise rates of 2 to 20 mm yr-1 during the next century could accelerate historical cliff retreat rates in Southern California by an average of 0.10 - 0.56 m yr-1.

  14. Sub-ice-shelf sediments record history of twentieth-century retreat of Pine Island Glacier

    NASA Astrophysics Data System (ADS)

    Smith, J. A.; Andersen, T. J.; Shortt, M.; Gaffney, A. M.; Truffer, M.; Stanton, T. P.; Bindschadler, R.; Dutrieux, P.; Jenkins, A.; Hillenbrand, C.-D.; Ehrmann, W.; Corr, H. F. J.; Farley, N.; Crowhurst, S.; Vaughan, D. G.

    2016-11-01

    The West Antarctic Ice Sheet is one of the largest potential sources of rising sea levels. Over the past 40 years, glaciers flowing into the Amundsen Sea sector of the ice sheet have thinned at an accelerating rate, and several numerical models suggest that unstable and irreversible retreat of the grounding line—which marks the boundary between grounded ice and floating ice shelf—is underway. Understanding this recent retreat requires a detailed knowledge of grounding-line history, but the locations of the grounding line before the advent of satellite monitoring in the 1990s are poorly dated. In particular, a history of grounding-line retreat is required to understand the relative roles of contemporaneous ocean-forced change and of ongoing glacier response to an earlier perturbation in driving ice-sheet loss. Here we show that the present thinning and retreat of Pine Island Glacier in West Antarctica is part of a climatically forced trend that was triggered in the 1940s. Our conclusions arise from analysis of sediment cores recovered beneath the floating Pine Island Glacier ice shelf, and constrain the date at which the grounding line retreated from a prominent seafloor ridge. We find that incursion of marine water beyond the crest of this ridge, forming an ocean cavity beneath the ice shelf, occurred in 1945 (±12 years); final ungrounding of the ice shelf from the ridge occurred in 1970 (±4 years). The initial opening of this ocean cavity followed a period of strong warming of West Antarctica, associated with El Niño activity. Thus our results suggest that, even when climate forcing weakened, ice-sheet retreat continued.

  15. Comparative assessment of the incidence of vertical root fractures between conventional versus surgical endodontic retreatment.

    PubMed

    Karygianni, L; Krengel, M; Winter, M; Stampf, S; Wrbas, K T

    2014-11-01

    Vertical root fractures (VRFs) are a common cause of tooth loss. Little evidence exists though, relating the incidence of VRFs to the type of endodontic retreatment. This retrospective study aimed at evaluating the impact of conventional versus surgical endodontics on root canal-filled teeth with VRFs. Over a period of 13 years, 200 endodontically retreated teeth from 192 patients with VRFs were extracted and further examined. VRFs were assessed in relation to age, gender, tooth group, clinical signs, extension on the root surface, patency, as well as type of endodontic retreatment and restoration. Statistical analysis was conducted using a Cox PH Model, Chi-squared, Wilcoxon rank-sum, and Log rank tests at a significance level of 5 %. The majority of teeth with VRFs (62.31 %) had undergone the combination of conventional root canal retreatment and apical surgery. Women (64.06 %) presented VRFs more frequently than men (35.94 %) at the mean age of 51.1 and 55.1 years, respectively. Maxillary first (17.5 %) and second (16.5 %) premolars, restored by a resin-based material without a post (56.28 %) were more susceptible to VRFs. Apically initiated (84.1 %) VRFs could be diagnosed more easily on radiographs. The type of endodontic treatment strongly correlated with VRFs. The prevalence of VRFs in teeth having undergone both conventional and surgical endodontic retreatment could be attributed, among others, to additive dentin damage related to the aforementioned endodontic procedures. The possible involvement of endodontic retreatment in the multifactorial etiology of VRFs needs to be taken into consideration in clinical practice.

  16. The influence of previous non-surgical re-treatment on the outcome of endodontic surgery.

    PubMed

    Taschieri, S; Machtou, P; Rosano, G; Weinstein, T; Del Fabbro, M

    2010-01-01

    The aim of this study was to evaluate retrospectively if the outcome of periradicular surgery at four year follow-up can be affected by a previous orthograde re-treatment. Eighty-one patients with 118 endodontically treated teeth who underwent surgical retreatment were divided in three groups. In group OA endodontic re-treatment was feasible and was attempted but, owing to the persistence of clinical symptoms and radiographic lesion, apical surgery was performed 4.8 ± 3.5 months later. In group OF endodontic re-treatment was feasible but was not performed, with subsequent apical surgery. In group ONF endodontic re-treatment was unfeasible, and apical surgery was performed. The treatment outcome was assessed four years postsurgery according to clinical and radiographic criteria. Seventy-six patients (112 teeth) could be evaluated at four years. In the ONF group five anterior maxillary teeth, belonging to three female patients, failed to heal. Three failures in three patients occurred in the OF group. No failure was recorded in the OA group. Three teeth in three patients were classified as uncertain healing in each group. The outcome of group OA resulted significantly better than the other treatment groups for both tooth-based and patient-based analysis. No significant effect was found as related to jaw, tooth type, presence of a post. A significant relation was found with gender (P=0.04). A negative correlation was found between outcome and age (Pearson's coefficient=-0.09), suggesting that the probability of failure increases with age. Orthograde re-treatment prior to apical surgery could be considered a valid alternative to tooth extraction and not an over-treatment.

  17. Treated pulmonary arteriovenous malformations: patterns of persistence and associated retreatment success.

    PubMed

    Woodward, Catherine S; Pyeritz, Reed E; Chittams, Jessie L; Trerotola, Scott O

    2013-12-01

    To determine the relative frequencies of persistence patterns in treated pulmonary arteriovenous malformations (PAVMs) and to assess whether there is a difference in retreatment outcomes between PAVMs persisting via recanalization and those persisting via reperfusion. Between May 2003 and May 2011, 23 patients (10 male, 13 female; mean age, 44 years ± 18 [standard deviation]; age range, 12-72 years) who had PAVM embolization, persistence by computed tomography (CT), and a follow-up pulmonary arteriogram were included. This retrospective study was approved by the institutional review board and was fully HIPAA compliant. PAVMs were categorized as having recanalization, defined as persistence maintained by flow through a previously placed coil nest; reperfusion, defined as persistence through small feeders from adjacent normal pulmonary arteries; or incomplete treatment. Fifty-three persistent PAVMs were characterized; 38 of which had postretreatment CT data (median follow-up, 1 year). The retreatment success rate, defined by sac shrinkage on CT images, was assessed. Recanalization was the most common pattern, occurring in 91% (n = 48) of 53 PAVMs. Pulmonary-to-pulmonary reperfusion occurred in 24% (n = 13) of 53 PAVMs. Angioarchitecture, coil-sac distance, coil number, and feeder diameter did not significantly differ between recanalized and reperfused PAVMs. There was a significant (P = .014) difference in retreatment success; retreatment was successful in 84% (n = 27) of 32 recanalized PAVMs but only 44% (n = 4) of nine reperfused PAVMs. Recanalization through previously placed coils is the most common pattern of PAVM persistence and responds best to retreatment. Pulmonary-to-pulmonary reperfusion is less common and more difficult to re-treat successfully. Online supplemental material is available for this article. © RSNA, 2013.

  18. Outcome of nonsurgical retreatment and endodontic microsurgery: a meta-analysis.

    PubMed

    Kang, Minji; In Jung, Hoi; Song, Minju; Kim, Sue Youn; Kim, Hyeon-Cheol; Kim, Euiseong

    2015-04-01

    The purpose of this study was to evaluate and compare the clinical and radiographic outcomes of nonsurgical endodontic retreatment and endodontic microsurgery by a meta-analysis. Electronic databases including PubMed, Embase, Medline, and The Cochrane Library were searched, and the references of related articles were manually searched to identify all the clinical studies that evaluated the clinical and radiographic outcomes after retreatment or microsurgery. The first and second screening processes were conducted by three reviewers independently. The final studies were selected after strict application of the inclusion and exclusion criteria. The random effects meta-analysis model with the DerSimonian-Laird pooling method was performed. The weighted pooled success rates and 95 % confidence interval estimates of the outcome were calculated. Additionally, the effects of the follow-up period and study quality were investigated by a subgroup analysis. Endodontic microsurgery and nonsurgical retreatment have stable outcomes presenting 92 and 80 % of overall pooled success rates, respectively. The microsurgery group had a significantly higher success rate than the retreatment group. When the data were organized and analyzed according to their follow-up periods, a significantly higher success rate was found for the microsurgery group in the short-term follow-up (less than 4 years), whereas no significant difference was observed in the long-term follow-up (more than 4 years). Endodontic microsurgery was confirmed as a reliable treatment option with favorable initial healing and a predictable outcome. Clinicians may consider the microsurgery as an effective way of retreatment as well as nonsurgical retreatment depending on the clinical situations.

  19. Effects of ongoing glacier retreat on steep valley-side drift slopes in the upper Bødalen valley, western Norway

    NASA Astrophysics Data System (ADS)

    Laute, Katja; Beylich, Achim A.; Oppikofer, Thierry

    2013-04-01

    The general pattern and dominant trend of today's mountain glaciers worldwide is a retreat of glacier fronts, indicating a significant volume decrease. Negative glacier net balances have been recorded for all Scandinavian glaciers after 1999. The ongoing glacier retreat enlarges freshly exposed proglacial areas which are characterized by e.g. comparably higher intensities of denudational slope processes and higher sediment availability. This study focuses on influences of rapid glacier regression on contemporary surface processes acting on steep valley-side drift slopes in a characteristic steep, parabolic-shaped and glacier-fed valley (Bødalen,) located on the western side of the Jostedalsbreen ice cap in western Norway. The Bødalsbreen is one of the glaciers with the highest retreat rate in entire Norway. Since the Little Ice Age (LIA) glacier maximum advance (1750) the glacier retreated ca. 1.500 m, including 65 m of retreat within the period of 2001 to 2010. Due to this retreat large areas of unstable hillslopes covered by glacial deposits from the LIA lateral moraines have been exposed. A combination of high resolution terrestrial laser scanning (TLS) and a designed monitoring program has been applied to a selected hillslope site on the eastern flank of the Bødalsbreen. Three sequential terrestrial laser scans have been acquired in the summers of 2010, 2011 and 2012. The analysis of the three series of the high resolution point clouds enables (i) the detection of unstable slope areas, (ii) areas characterized primarily by erosion or deposition processes and (iii) to quantify volumes of mass transfers at the scanned site. The results from the TLS measurements are combined with the results from the monitoring program (installations in operation since 2009) which includes remote cameras for monitoring rapid mass movement events (avalanches, slush- and debris flows), stone tracer lines for measuring surface movements as well as temperature loggers both in rock

  20. An Intensive Look at Intensity and Language Learning

    ERIC Educational Resources Information Center

    Collins, Laura; White, Joanna

    2011-01-01

    In this longitudinal study we investigated whether different distributions of instructional time would have differential effects on the acquisition of English by young (aged 11-12 years) French-speaking learners. Eleven classes of Grade 6 students (N = 230) in two versions of a similar intensive English as a second language program were followed…

  1. An Intensive Look at Intensity and Language Learning

    ERIC Educational Resources Information Center

    Collins, Laura; White, Joanna

    2011-01-01

    In this longitudinal study we investigated whether different distributions of instructional time would have differential effects on the acquisition of English by young (aged 11-12 years) French-speaking learners. Eleven classes of Grade 6 students (N = 230) in two versions of a similar intensive English as a second language program were followed…

  2. Retreatment with Bendamustine-Bortezomib-Dexamethasone in a Patient with Relapsed/Refractory Multiple Myeloma

    PubMed Central

    Nappi, Davide; Di Perna, Maria; Zacheo, Irene; Pareto, Anna Emanuele; Picardi, Marco; Pane, Fabrizio

    2016-01-01

    The clinical management of relapsed/refractory multiple myeloma and the correct choice of the most suitable therapy in heavily pretreated and fragile patients are tough clinical issues for clinicians. In advanced phases of disease, the choice of available therapies becomes very poor, and the retreatment with previously adopted and effective therapy, although unpredictable, could be an effective option. In this report, we describe the clinical history of a patient, previously treated with 9 lines of therapy, refractory to bortezomib and IMIDs, for whom the retreatment with bendamustine resulted in a stable disease with good quality of life. PMID:27867671

  3. Rift in Antarctic Glacier: a Unique Chance to Study Ice Shelf Retreat

    NASA Technical Reports Server (NTRS)

    Howat, Ian M.; Jezek, Ken; Studinger, Michael; Macgregor, Joseph A.; Paden, John; Floricioiu, Dana; Russell, Rob; Linkswiler, Matt; Dominguez, Roseanne T.

    2012-01-01

    It happened again, but this time it was caught in the act. During the last week of September 2011 a large transverse rift developed across thefloating terminus of West Antarcticas PineIsland Glacier, less than 5 years after its lastlarge calving event, in 2007 (Figure 1). PineIsland Glaciers retreat has accelerated substantiallyin the past 2 decades, and it is nowlosing 50 gigatons of ice per year, or roughly 25 of Antarcticas total annual contributionto sea level rise [Rignot et al., 2008]. The glaciers recent accelerated retreat is likely triggered by ocean warming and increased submarine melting. As such, it is of significant interest to glaciologists and of heightened societal relevance.

  4. Pretreatment neutrophil-to-lymphocyte ratio in peripheral blood was associated with pulmonary tuberculosis retreatment

    PubMed Central

    Yin, Yongmei; Kuai, Shougang; Liu, Jun; Zhang, YingYing; Shan, Zhongbao; Gu, Lan; Huang, Qiusheng

    2016-01-01

    Introduction The neutrophil-to-lymphocyte ratio (NLR) is a readily available biomarker associated with recurrence and survival in various diseases. The objective of this study was to investigate the relationship between NLR and pulmonary tuberculosis (PTB) retreatment. Material and methods This was a case-control study that included 306 newly diagnosed cases of PTB in the clinical database of the Infectious Hospital of Wuxi from December 2009 to December 2011. Of the 306 patients, a total of 68 cases were followed up with TB retreatment. The remaining 238 PTB patients who completed anti-TB treatment and were cured without retreatment were selected as controls. Results According to the ROC curve, the best cut-off value of NLR was 2.53, with a sensitivity of 70.6% and a specificity of 45.4%. The NLR ≥ 2.53 before anti-TB treatment was associated with PTB retreatment (OR = 1.994, 95% CI: 1.116–3.564; adjusted OR (AOR) = 2.409, 95% CI: 1.212–4.788). The retreatment rates with NLR ≥ 2.53 and NLR < 2.53 were 27.1% and 15.5%, respectively, with a significant difference (log-rank test; p = 0.010). Additionally, cavitation on chest X-ray (OR = 2.922, 95% CI: 1.654–5.411; AOR = 2.482, 95% CI: 1.230–5.007), history of smoking (OR = 2.202, 95% CI: 1.158–3.493; AOR = 2.321, 95% CI: 1.135–4.745) and age ≥ 60 (OR = 3.828, 95% CI: 1.626–9.015; AOR = 2.931, 95% CI: 1.122–7.653) were also associated with PTB retreatment. Conclusions NLR ≥ 2.53 is predictive of PTB retreatment. Otherwise, initial cavitation on chest X-ray, history of smoking, and age of ≥ 60 are also risk factors for PTB retreatment. PMID:28261295

  5. Retreatment with brentuximab vedotin in patients with CD30-positive hematologic malignancies

    PubMed Central

    2014-01-01

    Background Brentuximab vedotin is a CD30-directed antibody-drug conjugate. Retreatment with brentuximab vedotin monotherapy was investigated in patients with CD30-positive Hodgkin lymphoma (HL) or systemic anaplastic large cell lymphoma (ALCL) who relapsed after achieving complete or partial remission (CR or PR) with initial brentuximab vedotin therapy in a previous study (ClinicalTrials.gov NCT00947856). Methods Twenty-one patients with HL and 8 patients with systemic ALCL were retreated; 3 patients with systemic ALCL were retreated twice. Patients generally received brentuximab vedotin 1.8 mg/kg intravenously approximately every 3 weeks over 30 minutes as an outpatient infusion. The primary objectives of this study were to assess safety and to estimate antitumor activity of brentuximab vedotin retreatment. Results The objective response rate was 60% (30% CR) in HL patients and 88% (63% CR) in systemic ALCL patients. The estimated median duration of response for patients with an objective response was 9.5 months (range, 0.0+ to 28.0+ months) at the time of study closure. Of the 19 patients with objective response, 7 patients had not had an event of disease progression or death at the time of study closure; duration of response for these patients ranged from 3.5 to 28 months. Of the 11 patients with CR, 45% had response durations of over 1 year. Adverse events (AEs) occurring in ≥25% of patients during the retreatment period were generally similar in type and frequency to those observed in the pivotal trials of brentuximab vedotin monotherapy, with the exception of peripheral neuropathy, which is known to have a cumulative effect. Grade 3 or higher events were observed in 48% of patients; these were generally transient and managed by dose modifications or delays. Deaths due to AEs occurred in 3 HL patients; none were considered to be related to brentuximab vedotin retreatment. Discussion With the exception of a higher rate of peripheral motor neuropathy

  6. Retreat history of the last glacial maximum ice sheet in Ross Sea, Antarctica

    NASA Astrophysics Data System (ADS)

    Shipp, Stephanie Staples

    High-resolution geophysical and geologic data were acquired in western and central Ross Sea, Antarctica, to determine the: (1) maximum extent and configuration of the ice sheet during the Last Glacial Maximum (LGM); (2) conditions and processes at the base of the expanded ice sheet and their role in ice stream activity; and (3) relative retreat history of the ice sheet. This information can provide geologic constraints for modeling of ice-sheet retreat. The research formed the basis for development of a public Web site (http://www.glacier.rice.edu) and for middle-school earth-science instructional materials. Based on identification of isolated grounding-zone wedges and consistency of mega-scale glacial lineations, the LGM ice edge reached the Coulman Island region in western Ross Sea. The maximum extent in central Ross Sea occurred at the continental-shelf edge, based on the presence of mega-scale glacial lineations, glacio-tectonic features, and shelf-edge gullies. Streaming ice, overlying a deforming bed typically <5 m in thickness, filled the troughs. Thinner, divergent, slower moving ice, not underlain by deforming sediment, occupied the bank tops. The ice sheet eroded and conveyed sediment from the inner regions toward the outer shelf, where the material was deposited at the grounding line. No features associated with meltwater occur; water available to the subglacial system probably was incorporated into a deforming unit. The ice sheet may have undergone an initial phase of mass wasting, based the large, arcuate iceberg furrows associated with the grounding zones. Ice retreated first from western Ross Sea, possibly because of a diminished contribution from the East Antarctic Ice Sheet. Ice retreat from central Ross Sea lagged that of western Ross Sea. The banks remained ice covered after ice retreat from the troughs; ice shelves may have covered the troughs. During retreat, the grounded ice reworked the substrate into back-stepping grounding-zone wedges and

  7. Different Patterns of Restoration Provision Between Initial Endodontic Treatment and Retreatment: A Retrospective Clinical Study.

    PubMed

    Agrafioti, Anastasia; Giannakoulas, Dimitrios G; Kournetas, Nikos; Grigoriou, Stamatina; Kontakiotis, Evangelos G

    The aim of this study was to investigate the relationship between type of endodontic treatment and choice of definitive restoration and to show the prevalence of endodontic treatment options according to patient age and type of tooth. Data were collected from the archive system of the School of Dentistry, National and Kapodistrian University of Athens in Athens, Greece. The sample included endodontically treated teeth being restored definitively at the time of data collection. Statistically significant difference was found regarding the type of restoration between initial endodontic treatments and retreatments (P < .001). Endodontic retreatment seemed to have a significant effect on the choice of definitive restoration of the tooth.

  8. Opportunities for epilepsy: Outcomes of the Milken Institute State of the Science Retreat.

    PubMed

    Dumanis, Sonya B; Riley, Ekemini A U; Briggs, LaTese; Kim, YooRi; Lontok, Erik; Salka, Danielle; Stevens, Melissa

    2017-03-01

    The Milken Institute Center for Strategic Philanthropy has launched a Giving Smarter Program in Epilepsy to inform philanthropists on the state of the science for the epilepsy field, key challenges, and solutions to address them. As part of the program, the Milken Institute Center for Strategic Philanthropy hosted a retreat to identify strategic investments that would accelerate epilepsy research to ultimately improve care. The top three prioritized opportunities from the retreat were to 1) invest in data standards and analytical tool development, 2) support young investigators, and 3) promote cross-sector collaborations especially between basic scientists, preclinical researchers, clinicians, and patients.

  9. Effects of errors in velocity tilt on maximum longitudinal compression during neutralized drift compression of intense beam pulses: II. Analysis of experimental data of the Neutralized Drift Compression eXperiment-I (NDCX-I)

    NASA Astrophysics Data System (ADS)

    Massidda, Scott; Kaganovich, Igor D.; Startsev, Edward A.; Davidson, Ronald C.; Lidia, Steven M.; Seidl, Peter; Friedman, Alex

    2012-06-01

    Neutralized drift compression offers an effective means for particle beam focusing and current amplification with applications to heavy ion fusion. In the Neutralized Drift Compression eXperiment-I (NDCX-I), a non-relativistic ion beam pulse is passed through an inductive bunching module that produces a longitudinal velocity modulation. Due to the applied velocity tilt, the beam pulse compresses during neutralized drift. The ion beam pulse can be compressed by a factor of more than 100; however, errors in the velocity modulation affect the compression ratio in complex ways. We have performed a study of how the longitudinal compression of a typical NDCX-I ion beam pulse is affected by the initial errors in the acquired velocity modulation. Without any voltage errors, an ideal compression is limited only by the initial energy spread of the ion beam, ΔΕb. In the presence of large voltage errors, δU≫ΔEb, the maximum compression ratio is found to be inversely proportional to the geometric mean of the relative error in velocity modulation and the relative intrinsic energy spread of the beam ions. Although small parts of a beam pulse can achieve high local values of compression ratio, the acquired velocity errors cause these parts to compress at different times, limiting the overall compression of the ion beam pulse.

  10. Knickpoint retreat and landscape disequilibrium on the James River from the Piedmont through the Valley and Ridge, central Virginia, USA

    NASA Astrophysics Data System (ADS)

    Hancock, G.; Harbor, D.; Felis, J.

    2003-12-01

    Several lines of evidence indicate landscape disequilibrium in the James River basin in central Virginia. The river longitudinal profile possesses pronounced convexities and apparently migratory knickzones. Along much of its length, it flows in a narrow inner valley incised into a discontinuous, low-relief upland. In the inner Piedmont, the 150 m wide river channel occupies an incised valley that can be as little as 600 m wide and 75 m deep. Broad fluvial terraces are often found capping the high topography directly adjacent to the valleys, and we use these disconnected terraces to reconstruct paleo-river profiles spanning ~200 km in the Piedmont. These high, extensive terraces disappear in the James River Gap through the Blue Ridge, but reappear with less distinction in the carbonate rocks of the Great Valley. The river remains incised within the Great Valley, with prominent knickzones ~60-100 km above the Blue Ridge gap found on both the mainstem and tributaries. We dated terraces in the Piedmont with in-situ 10Be profiles and a depth integration technique. Dates from the highest terrace level at three locations along ~100 km of the river are ~1 m.yr., suggesting rapid river incision rates of ~55 m/m.yr. We also have documented exceptionally high incision rates along a tributary in the Great Valley. This dating suggests disequilibrium erosion was initiated and has persisted here during the late Quaternary. Assuming the incision is accomplished largely by knickpoint retreat, the dates suggest past retreat rates of up to one m/yr in the Piedmont and 250 m/m.yr. between the outer Piedmont and the Great Valley. We have two hypotheses for how this recent incision was triggered: 1) response to flexural-isostatic uplift generated by drainage basin capture and associated denudation and/or 2) the shift to more rapid climate fluctuations in the early Pleistocene. Additionally, we suggest two interpretations for the generation of the extensive high terrace surfaces. They

  11. Longitudinal image registration with non-uniform appearance change.

    PubMed

    Csapo, Istvan; Davis, Brad; Shi, Yundi; Sanchez, Mar; Styner, Martin; Niethammer, Marc

    2012-01-01

    Longitudinal imaging studies are frequently used to investigate temporal changes in brain morphology. Image intensity may also change over time, for example when studying brain maturation. However, such intensity changes are not accounted for in image similarity measures for standard image registration methods. Hence, (i) local similarity measures, (ii) methods estimating intensity transformations between images, and (iii) metamorphosis approaches have been developed to either achieve robustness with respect to intensity changes or to simultaneously capture spatial and intensity changes. For these methods, longitudinal intensity changes are not explicitly modeled and images are treated as independent static samples. Here, we propose a model-based image similarity measure for longitudinal image registration in the presence of spatially non-uniform intensity change.

  12. Reconceptualizing Leadership in Migrant Communities: Latina/o Parent Leadership Retreats as Sites of Community Cultural Wealth

    ERIC Educational Resources Information Center

    Nava, Pedro E.; Lara, Argelia

    2016-01-01

    This article examines how the Education Leadership Foundation (a leadership development community based organization) in partnership with the Migrant Education Program use parent retreats for building leadership, and skill development of migrant farm-working families. Utilizing cooperative and community responsive practices, these retreats build…

  13. Reconceptualizing Leadership in Migrant Communities: Latina/o Parent Leadership Retreats as Sites of Community Cultural Wealth

    ERIC Educational Resources Information Center

    Nava, Pedro E.; Lara, Argelia

    2016-01-01

    This article examines how the Education Leadership Foundation (a leadership development community based organization) in partnership with the Migrant Education Program use parent retreats for building leadership, and skill development of migrant farm-working families. Utilizing cooperative and community responsive practices, these retreats build…

  14. Extent of West Antarctic Ice Sheet During the LGM, Timing of Retreat and Potential Contribution to MWP Ia

    NASA Astrophysics Data System (ADS)

    Anderson, J.; Lowe, A.; Mosola, A.; Oakes, L.

    2005-12-01

    An extensive marine geological data set has been acquired from the West Antarctic continental shelf, including all of the major troughs that occur seaward of major drainage outlets. Swath bathymetry records show a progression of geomorphic features on the continental shelf that range from subglacial meltwater features to drumlin fields to mega-scale glacial lineations in an offshore direction. There is evidence for catastrophic outbursts of meltwater beneath the ice sheet within Pine Island Bay and Marguerite Bay. Mega-scale glacial lineations comprised of soft, deformation till indicate that the ancestral WAIS was drained through ice streams that, in the case of the eastern Ross Sea, extended over a thousand kilometers to the continental shelf edge. Hence, over-extension of ice streams and subglacial meltwater outbursts may have contributed to ice sheet instability and retreat. The largest drainage system occurs in the eastern Ross Sea and southern Weddell Sea. Severe sea ice conditions have limited data acquisition in the southern Weddell Sea, but a detailed study has been conducted in the eastern Ross Sea. There, the ice sheet appears to have retreated rapidly from the continental shelf, but the distribution of grounding zone wedges suggests a somewhat diachronous retreat for different ice streams. Our efforts to constrain the timing of ice sheet retreat from the shelf focused on dating the oldest glaciomarine sediments resting on till. Unfortunately, no carbonate was recovered from cores in the eastern Ross Sea, so the timing of retreat of this portion of the ice sheet is based on TOC dates, and uncertainty about reservoir effects limits our ability to constrain the retreat history. What is implied by the combined data is that the ice sheet appears to have retreated rapidly from the shelf soon after the LGM. In western Marie Byrd Land, the ice sheet retreated from the continental shelf prior to 13 Ka. In Pine Island Bay, retreat occurred in two stages. The ice

  15. Evolving force balance at Columbia Glacier, Alaska, during its rapid retreat

    USGS Publications Warehouse

    O'Neel, S.; Pfeffer, W.T.; Krimmel, R.; Meier, M.

    2005-01-01

    Changes in driving and resistive stresses play an essential role in governing the buoyancy forces that are important controls on the speed and irreversibility of tidewater glacier retreats. We describe changes in geometry, velocity, and strain rate and present a top-down force balance analysis performed over the lower reach of Columbia Glacier. Our analysis uses new measurements and estimates of basal topography and photogrammetric surface velocity measurements made between 1977 and 2001, while assuming depth-independent strain. Sensitivity tests show that the method is robust and insensitive to small changes in the calculation parameters. Spatial distributions of ice speed show little correspondence with driving stress. Instead, spatial patterns of ice speed exhibit a nonlinear correspondence with basal drag. Primary resistance to flow comes from basal drag, but lateral drag becomes increasingly more important throughout the retreat, which may account for observed increases in speed. Maximum basal drag is always located in a prominent constriction located ~12 km upstream from the preretreat terminus. Once the terminus retreated into deep water off the terminal moraine marking the modern maximum extent, the upstream location of this maximum basal drag helped to promote thinning and decrease effective pressure in the lower region by limiting replenishing ice flow from upstream. An increase in both ice velocity and calving resulted, initiating what appears to be an irreversible retreat. Copyright 2005 by the American Geophysical Union.

  16. They're M-e-e-elting!: An Investigation of Glacial Retreat in Antarctica

    ERIC Educational Resources Information Center

    Bugg, Samuel R., IV; Constible, Juanita; Kaput, Marianne; Lee, Richard E., Jr.

    2007-01-01

    In this article, the authors describe the mechanics of They're M-e-e-elting!, an activity wherein middle school students can simulate glacial retreat in Antarctica. They're M-e-e-elting! allows students to melt glaciers, change the water level and salinity of the Southern Ocean, and examine alterations to the Antarctic food web--all without…

  17. Observations and modeling of fjord sedimentation during the 30 year retreat of Columbia Glacier, AK

    USGS Publications Warehouse

    Love, Katherine B; Hallet, Bernard; Pratt, Thomas L.; O'Neel, Shad

    2016-01-01

    To explore links between glacier dynamics, sediment yields and the accumulation of glacial sediments in a temperate setting, we use extensive glaciological observations for Columbia Glacier, Alaska, and new oceanographic data from the fjord exposed during its retreat. High-resolution seismic data indicate that 3.2 × 108 m3 of sediment has accumulated in Columbia Fjord over the past three decades, which corresponds to ~5 mm a−1 of erosion averaged over the glaciated area. We develop a general model to infer the sediment-flux history from the glacier that is compatible with the observed retreat history, and the thickness and architecture of the fjord sediment deposits. Results reveal a fivefold increase in sediment flux from 1997 to 2000, which is not correlated with concurrent changes in ice flux or retreat rate. We suggest the flux increase resulted from an increase in the sediment transport capacity of the subglacial hydraulic system due to the retreat-related steepening of the glacier surface over a known subglacial deep basin. Because variations in subglacial sediment storage can impact glacial sediment flux, in addition to changes in climate, erosion rate and glacier dynamics, the interpretation of climatic changes based on the sediment record is more complex than generally assumed.

  18. Retreating behavior of a charged ionic liquid droplet in a dielectric liquid under electric field

    NASA Astrophysics Data System (ADS)

    Ahn, Myung Mo; Im, Do Jin; Kang, In Seok

    2013-11-01

    Ionic liquids show great promise as excellent solvents or catalysts in energy and biological fields due to their unique chemical and physical properties. The ionic liquid droplets in microfluidic systems can also be used as a potential platform for chemical biological reactions. In order to control electrically the ionic liquid droplets in a microfluidic device, the charging characteristics of ionic liquid droplets need to be understood. In this work, the charging characteristics of various ionic liquids are investigated by using the parallel plate electrodes system. Under normal situation, a charged droplet shows bouncing motion between electrodes continuously. However, for some special ionic liquids, interesting retreating behavior of charged ionic liquid droplet has been observed. This retreating behavior of ionic liquid droplet has been analyzed experimentally by the image analysis and the electrometer signal analysis. Based on the hypothesis of charge leakage of the retreating ionic liquid droplets, FT-IR spectroscopy analysis has also been performed. The retreating behavior of ionic liquid droplet is discussed from the intermolecular point of view according to the species of ionic liquids. This research was supported by grant No. 2013R1A1A2011956 funded by the Ministry of Science, ICT and Future Planning (MSIP) and by grant No. 2013R1A1A2010483 funded by the Ministry of Education, Science and Technology (MEST) through the NRF.

  19. WAIS retreat in eastern Ross Sea during Meltwater Pulse-1a

    NASA Astrophysics Data System (ADS)

    Bart, Phil; DeCesare, Matthew; McGlannan, Austin; Danielson, Matthew

    2017-04-01

    The timing of MWPs are well constrained from dated coral successions. However, the temporal linkage between ice sheet retreat and MWPs remains controversial partly due to the difficulty of generating reliable deglacial chronologies from proximal Antarctic marine basins. Here we show an exceptional set of foraminiferal radiocarbon dates produced from ice-proximal deposits in the eastern Ross Sea that are well-constrained by seafloor geomorphology and core sedimentology. These radiocarbon ages demonstrate that an initial short distance retreat of ˜50 km had begun by ˜14,700 ±400 years ago, corresponding to the onset of MWP-1a. The WAIS paused for ˜3,200 years to deposit a series of Grounding Zone Wedges, or sub-aqueous terminal moraines. Ice shelf collapse at 12,400 ±300 years ago preceded a 200 km retreat of the WAIS at 11,500 ±300 years ago, i.e., at the onset of MWP-1b. These results provide conclusive evidence that the WAIS retreated during two distinct intervals of rapid sea-level rise. Please fill in your abstract text.

  20. A Century of Retreat at Portage Glacier, South-Central Alaska

    USGS Publications Warehouse

    Kennedy, Ben W.; Trabant, Dennis C.; Mayo, Lawrence R.

    2006-01-01

    Introduction: The Portage Glacier, in south-central Alaska, is viewed by thousands of visitors annually who come to the U.S. Forest Service Begich, Boggs Visitor Center located on the road system between Anchorage and Whittier, Alaska. During the past century, the terminus of the glacier has retreated nearly 5 kilometers to its present location (fig. 1). Like other glaciers that terminate in water, such as Columbia Glacier near Valdez or Mendenhall Glacier near Juneau, Portage Glacier has experienced accelerated retreats in recent decades that likely were initially triggered by climate change begun at the end of the Little Ice Age in the mid-1800s and subsequently controlled in recent history primarily by calving of the glacier terminus. Photographic records of the terminus covering 1914 until present day track the patterns of retreat. These data, coupled with USGS climate information collected from the southern end of the ice field, provide insight to the patterns of retreat that might be observed in the future.

  1. Modeling the retreat of the Jakobshavn Glacier from the LIA and into the future

    NASA Astrophysics Data System (ADS)

    Steiger, Nadine; Hestnes Nisancioglu, Kerim; Åkesson, Henning; Maghami Nick, Faezeh

    2017-04-01

    Many marine-terminating glaciers on Greenland have experienced rapid retreat and acceleration during the last decades, coinciding with increased air and ocean temperatures. Destabilized marine-terminating glaciers have been capable of discharging vast amounts of ice into the ocean, contributing significantly to sea-level rise. In order to conduct prospective simulations of the glaciers' development and their future contribution to sea-level rise, it is crucial to understand the dynamics and triggers of the past retreat, as well as the relative importance of the external forcing versus fjord geometry. Using an idealized numerical flowband model1,2, we are able to reproduce the documented retreat of the Jakobshavn Glacier, western Greenland, since the Little Ice Age (LIA). Based on the results from the hindcast experiments, we investigate the relative role of climate forcing and fjord geometry on glacier stability and assess the potential for non-linear retreat in the coming 200 years. References: [1] Nick et al. 2009, Nature Geoscience, doi:10.1038/ngeo394. [2] Nick et al. 2013, Nature, doi:10.1038/nature12068

  2. Gully head retreat in the sub humid northwestern Ethiopian highlands: the Ene-Chilala catchment

    USDA-ARS?s Scientific Manuscript database

    In the northern highlands of Ethiopia, gully erosion is severe. Despite many efforts to implement gully prevention measures, controlling gully erosion remains a challenge. The objective is to better understand the regional gully erosion processes and to prevent gully head retreat. The study was cond...

  3. The Role of Adherence and Retreatment in De Novo Emergence of MDR-TB.

    PubMed

    Cadosch, Dominique; Abel Zur Wiesch, Pia; Kouyos, Roger; Bonhoeffer, Sebastian

    2016-03-01

    Treatment failure after therapy of pulmonary tuberculosis (TB) infections is an important challenge, especially when it coincides with de novo emergence of multi-drug-resistant TB (MDR-TB). We seek to explore possible causes why MDR-TB has been found to occur much more often in patients with a history of previous treatment. We develop a mathematical model of the replication of Mycobacterium tuberculosis within a patient reflecting the compartments of macrophages, granulomas, and open cavities as well as parameterizing the effects of drugs on the pathogen dynamics in these compartments. We use this model to study the influence of patient adherence to therapy and of common retreatment regimens on treatment outcome. As expected, the simulations show that treatment success increases with increasing adherence. However, treatment occasionally fails even under perfect adherence due to interpatient variability in pharmacological parameters. The risk of generating MDR de novo is highest between 40% and 80% adherence. Importantly, our simulations highlight the double-edged effect of retreatment: On the one hand, the recommended retreatment regimen increases the overall success rate compared to re-treating with the initial regimen. On the other hand, it increases the probability to accumulate more resistant genotypes. We conclude that treatment adherence is a key factor for a positive outcome, and that screening for resistant strains is advisable after treatment failure or relapse.

  4. Combining Adult and Adolescent Female Incest Survivors in a Weekend Retreat.

    ERIC Educational Resources Information Center

    Gilovitch, Karen Dashiff; Miller, Louise

    1994-01-01

    Traditional psychotherapy, individual or group, never thoroughly resolves issues of perceived culpability, positive identification with other survivors, grief, or low self-esteem. To address this issue, a weekend retreat was designed that joins adult and adolescent women who were sexually abused as children. The tremendous success of this modality…

  5. Spatio-temporal Variability of Coupling between Ice Retreat and Phytoplankton Blooms in the Southern Ocean

    NASA Astrophysics Data System (ADS)

    Li, Y.; Ji, R.; Jenouvrier, S.; Jin, M.; Stroeve, J. C.; Campbell, G. G.; Lynch, H.; Holland, M. M.

    2016-02-01

    Polar organisms are adapted to the strong seasonality of environmental conditions. A small timing mismatch among biological and environmental events could potentially have significant consequences for the entire food web. Phytoplankton blooms in the marginal ice zone (MIZ) and coastal polynyas of the Antarctic develop in a narrow growth window due to the constraints of multiple environmental factors (e.g., light, ice, mixing). Changes in sea ice coverage and ice retreat timing can directly affect the timing and magnitude of primary production in the region. So far, the spatio-temporal patterns of phytoplankton blooms and their links to environment have not been fully examined, limiting our ability to interpret the past, present and future of Antarctic ecosystems. In this study, we use the available satellite datasets of sea ice and ocean color to assess the links between sea ice and phytoplankton. Our results suggest that the timing of ice retreat has a strong impact on the timing of phytoplankton blooms over most of the Antarctic: earlier ice retreat is generally associated with earlier onset of phytoplankton bloom. However, there is also significant spatial variability in the coupling of these events: phytoplankton blooms in the northern MIZ edge and the eastern Antarctic polynyas are likely to decouple with sea ice retreat due to the distinct strong water-column mixing regime. Underlying mechanisms for the variability and potential implications for higher trophic levels (e.g., seabirds) in the Antarctic ecosystem are discussed.

  6. The Role of Adherence and Retreatment in De Novo Emergence of MDR-TB

    PubMed Central

    Cadosch, Dominique; Abel zur Wiesch, Pia; Kouyos, Roger; Bonhoeffer, Sebastian

    2016-01-01

    Treatment failure after therapy of pulmonary tuberculosis (TB) infections is an important challenge, especially when it coincides with de novo emergence of multi-drug-resistant TB (MDR-TB). We seek to explore possible causes why MDR-TB has been found to occur much more often in patients with a history of previous treatment. We develop a mathematical model of the replication of Mycobacterium tuberculosis within a patient reflecting the compartments of macrophages, granulomas, and open cavities as well as parameterizing the effects of drugs on the pathogen dynamics in these compartments. We use this model to study the influence of patient adherence to therapy and of common retreatment regimens on treatment outcome. As expected, the simulations show that treatment success increases with increasing adherence. However, treatment occasionally fails even under perfect adherence due to interpatient variability in pharmacological parameters. The risk of generating MDR de novo is highest between 40% and 80% adherence. Importantly, our simulations highlight the double-edged effect of retreatment: On the one hand, the recommended retreatment regimen increases the overall success rate compared to re-treating with the initial regimen. On the other hand, it increases the probability to accumulate more resistant genotypes. We conclude that treatment adherence is a key factor for a positive outcome, and that screening for resistant strains is advisable after treatment failure or relapse. PMID:26967493

  7. Onset of Major Antarctic Ice-Sheet Retreat Driven by Extensive Surface Melt

    NASA Astrophysics Data System (ADS)

    Deconto, R. M.; Pollard, D.

    2016-12-01

    New Antarctic ice-sheet modeling that considers previously underappreciated effects of surface meltwater on ice-sheet dynamics has demonstrated the sensitivity of the ice sheet to atmospheric warming in addition to sub-ice oceanic warming. Here, we improve on our paleo-calibrated modeling of future ice-sheet retreat, using a bias-corrected, high-resolution regional atmospheric model that synchronizes time-evolving atmospheric climatologies with the SSTs and subsurface ocean temperatures that drive oceanic sub-ice melt rates. This approach avoids previous assumptions about the lagged response of Southern Ocean SSTs and Antarctic air temperatures relative to future greenhouse-gas forcing and produces future Antarctic climatologies in better agreement with other recent studies. The specification of modern observed climate, used to apply anomaly corrections with our atmospheric model, is also improved by using a monthly climatology provided by the RACMO2 regional climate model. We find that predicted future rates and magnitudes of ice-sheet retreat and sea-level rise are similar to our previous simulations. However, the revised atmospheric forcing delays the timing of the onset of retreat, with potential implications for coastal planning and policy. These results show that the future onset of major Antarctic ice-sheet retreat will be highly dependent on the details of evolving Antarctic climate, which remains uncertain due to complex linkages with lower-latitude atmospheric dynamics, ocean-ice feedbacks, recovery of the ozone hole, and uncertain future greenhouse-gas forcing.

  8. They're M-e-e-elting!: An Investigation of Glacial Retreat in Antarctica

    ERIC Educational Resources Information Center

    Bugg, Samuel R., IV; Constible, Juanita; Kaput, Marianne; Lee, Richard E., Jr.

    2007-01-01

    In this article, the authors describe the mechanics of They're M-e-e-elting!, an activity wherein middle school students can simulate glacial retreat in Antarctica. They're M-e-e-elting! allows students to melt glaciers, change the water level and salinity of the Southern Ocean, and examine alterations to the Antarctic food web--all without…

  9. ASPIRE: Formation of Pre-Service Teachers through Leadership, Community Engagement and Retreat Training

    ERIC Educational Resources Information Center

    Hackett, Chris; Lavery, Shane

    2010-01-01

    This article explores the experiences of pre-service teachers who are involved in a program promoting leadership, community engagement and retreat training. It initially presents a review of the literature on the significant links between teacher commitment and quality teaching. It then describes how four significant dispositions: care,…

  10. Root canal retreatment using reciprocating and continuous rotary nickel-titanium instruments

    PubMed Central

    de Souza, Patricia Fonseca; Oliveira Goncalves, Leonardo Cantanhede; Franco Marques, Andre Augusto; Sponchiado Junior, Emilio Carlos; Roberti Garcia, Lucas da Fonseca; de Carvalho, Fredson Marcio Acris

    2015-01-01

    Objective: The complete filling material removal during endodontic retreatment is a clinical procedure difficult to achieve. The aim of this study was to evaluate the efficacy of reciprocating and continuous rotary nickel-titanium instruments used in root canal retreatment. Materials and Methods: Forty freshly extracted human premolars were cleaned and shaped by the crown-down technique, followed by filling by the lateral compaction technique. The teeth were randomly separated into two groups (n = 20), according to the system used for filling material removal: G1 - Reciproc and G2 - ProTaper Universal Retreatment System. The teeth were photographed under operating microscope at ×8 magnification; and the total area of the root canal and remaining filling material were quantified. Results: No statistically significant difference (P > 0.05) in residual filling material was observed between groups; however, the time required for filling removal was significantly shorter for Reciproc system (P < 0.05). Conclusions: It was observed remaining filling material in all teeth, irrespective of the system used; however, root canal retreatment was faster when reciprocating motion was used. PMID:26038656

  11. The outcome of endodontic retreatment: a 2-yr follow-up.

    PubMed

    Gorni, Fabio G M; Gagliani, Massimo M

    2004-01-01

    Retreatment is common in endodontics. The purpose of this article was to classify the different clinical situations encountered in retreatment cases and relate them to the outcome after an observation period of 24 months. A total of 425 patients (452 teeth) from 451 patients, consecutively admitted for root-canal retreatment, were monitored during a 24-month period. All teeth (254 molars, 107 premolars, and 91 single-root anterior teeth) were divided into two major categories: teeth with modified anatomy from previous endodontic treatment (root-canal-morphology altered) and teeth in which no significant anatomical changes were made by the former endodontic treatment (root-canal-morphology respected). Although the overall success was 69.03%, the success in the root-canal-morphology-respected group was 86.8% and in the root-canal-morphology-altered group 47% (Mann-Whitney U test p < 0.0001). The clinical success of an endodontic retreatment seems to depend on whether alterations in the natural course of the root canals were caused by previous root-canal treatment.

  12. Nonsurgical retreatment of teeth with periapical lesions previously managed by either endodontic or surgical intervention.

    PubMed

    Calişkan, Mehmet Kemal

    2005-08-01

    The purpose of this study was to evaluate the outcome of nonsurgical retreatment of teeth with periapical lesions, which had been previously managed by either endodontic or surgical intervention, and to identify factors that might influence the prognosis. Seventy-five endodontically and 11 surgically treated teeth with persisting periapical lesions ranging in size from 2 to 11 mm in diameter were included in this study. The teeth were nonsurgically retreated, using calcium hydroxide as intracanal medicament, and were followed for a period of 2 to 8 years. Clinical and radiographic assessment of retreatment showed that complete healing for all cases was 61.6% with an additional category of incomplete healing of 14%; 24.4% failed. The size of the periapical lesions and previous surgical treatment had marginally negative influences on the prognosis, but the differences were not statistically significant. The favourable results of this study demonstrated that nonsurgical root canal retreatment is an alternative to surgical intervention of postendodontic or postsurgical failure.

  13. Ocean forcing of Ice Sheet retreat in central west Greenland from LGM to the early Holocene

    NASA Astrophysics Data System (ADS)

    Jennings, Anne E.; Andrews, John T.; Ó Cofaigh, Colm; Onge, Guillaume St.; Sheldon, Christina; Belt, Simon T.; Cabedo-Sanz, Patricia; Hillaire-Marcel, Claude

    2017-08-01

    Three radiocarbon dated sediment cores from trough mouth fans on the central west Greenland continental slope were studied to determine the timing and processes of Greenland Ice Sheet (GIS) retreat from the shelf edge during the last deglaciation and to test the role of ocean forcing (i.e. warm ocean water) thereon. Analyses of lithofacies, quantitative x-ray diffraction mineralogy, benthic foraminiferal assemblages, the sea-ice biomarker IP25, and δ18 O of the planktonic foraminifera Neogloboquadrina pachyderma sinistral from sediments in the interval from 17.5-10.8 cal ka BP provide consistent evidence for ocean and ice sheet interactions during central west Greenland (CWG) deglaciation. The Disko and Uummannaq ice streams both retreated from the shelf edge after the last glacial maximum (LGM) under the influence of subsurface, warm Atlantic Water. The warm subsurface water was limited to depths below the ice stream grounding lines during the LGM, when the GIS terminated as a floating ice shelf in a sea-ice covered Baffin Bay. The deeper Uummannaq ice stream retreated first (ca. 17.1 cal ka BP), while the shallower Disko ice stream retreated at ca. 16.2 cal ka BP. The grounding lines were protected from accelerating mass loss (calving) by a buttressing ice shelf and by landward shallowing bathymetry on the outer shelf. Calving retreat was delayed until ca. 15.3 cal ka BP in the Uummannaq Trough and until 15.1 cal ka BP in the Disko Trough, during another interval of ocean warming. Instabilities in the Laurentide, Innuitian and Greenland ice sheets with outlets draining into northern Baffin Bay periodically released cold, fresh water that enhanced sea ice formation and slowed GIS melt. During the Younger Dryas, the CWG records document strong cooling, lack of GIS meltwater, and an increase in iceberg rafted material from northern Baffin Bay. The ice sheet remained in the cross-shelf troughs until the early Holocene, when it retreated rapidly by calving and strong

  14. Continuing evidence for poorer treatment outcomes for single male patients: Retreatment data from RTOG 97-14

    SciTech Connect

    Konski, Andre . E-mail: andre.konski@fccc.edu; DeSilvio, Michelle; Hartsell, William; Watkins-Bruner, Deborah; Coyne, James; Scarantino, Charles; JanJan, Nora

    2006-09-01

    Purpose: The specific aim of this study was to evaluate outcome differences by gender and partner status for patients treated on Radiation Therapy Oncology Group (RTOG) protocol 97-14. Methods and Materials: RTOG 97-14 randomized patients with metastatic breast or prostate cancer to bone to receive 8 Gy in 1 fraction or 30 Gy in 10 fractions. Retreatment rates and overall survival were made based upon gender, marital status, and Karnofsky Performance Status (KPS). The cumulative incidence method was used to estimate retreatment time at 36 months from enrollment, and Gray's test was used to test for treatment differences within the same groupings. Marital status, gender, KPS, and treatment were variables tested in a univariate Cox model evaluating the time to retreatment. Results: Married men and women and single women receiving 30 Gy had significantly longer time to retreatment, p = 0.0067, p = 0.0052, and p = 0.0009 respectively. We failed to show a difference in retreatment rates over time in single men receiving either 30 Gy or 8 Gy. Univariate analysis of the entire group determined patients receiving 30 Gy in 10 fractions significantly less likely to receive retreatment, p < 0.0001, with a trend toward single patients less likely to be re-treated, p = 0.07. Conclusion: Non-disease-related variables, such as social support, might influence the results of clinical trials with subjective endpoints such as retreatment rates. The statistically nonsignificant difference in the 36-month retreatment rates observed in single male patients receiving 8 Gy may be a result of inadequate social support systems in place to facilitate additional care. Patients receiving 8 Gy in a single fraction had significantly higher retreatment rates compared with patients receiving 30 Gy in 10 fractions.

  15. Repeated large-scale retreat and advance of Totten Glacier indicated by inland bed erosion.

    PubMed

    Aitken, A R A; Roberts, J L; van Ommen, T D; Young, D A; Golledge, N R; Greenbaum, J S; Blankenship, D D; Siegert, M J

    2016-05-19

    Climate variations cause ice sheets to retreat and advance, raising or lowering sea level by metres to decametres. The basic relationship is unambiguous, but the timing, magnitude and sources of sea-level change remain unclear; in particular, the contribution of the East Antarctic Ice Sheet (EAIS) is ill defined, restricting our appreciation of potential future change. Several lines of evidence suggest possible collapse of the Totten Glacier into interior basins during past warm periods, most notably the Pliocene epoch, causing several metres of sea-level rise. However, the structure and long-term evolution of the ice sheet in this region have been understood insufficiently to constrain past ice-sheet extents. Here we show that deep ice-sheet erosion-enough to expose basement rocks-has occurred in two regions: the head of the Totten Glacier, within 150 kilometres of today's grounding line; and deep within the Sabrina Subglacial Basin, 350-550 kilometres from this grounding line. Our results, based on ICECAP aerogeophysical data, demarcate the marginal zones of two distinct quasi-stable EAIS configurations, corresponding to the 'modern-scale' ice sheet (with a marginal zone near the present ice-sheet margin) and the retreated ice sheet (with the marginal zone located far inland). The transitional region of 200-250 kilometres in width is less eroded, suggesting shorter-lived exposure to eroding conditions during repeated retreat-advance events, which are probably driven by ocean-forced instabilities. Representative ice-sheet models indicate that the global sea-level increase resulting from retreat in this sector can be up to 0.9 metres in the modern-scale configuration, and exceeds 2 metres in the retreated configuration.

  16. Repeated large-scale retreat and advance of Totten Glacier indicated by inland bed erosion

    NASA Astrophysics Data System (ADS)

    Aitken, A. R. A.; Roberts, J. L.; Ommen, T. D. Van; Young, D. A.; Golledge, N. R.; Greenbaum, J. S.; Blankenship, D. D.; Siegert, M. J.

    2016-05-01

    Climate variations cause ice sheets to retreat and advance, raising or lowering sea level by metres to decametres. The basic relationship is unambiguous, but the timing, magnitude and sources of sea-level change remain unclear; in particular, the contribution of the East Antarctic Ice Sheet (EAIS) is ill defined, restricting our appreciation of potential future change. Several lines of evidence suggest possible collapse of the Totten Glacier into interior basins during past warm periods, most notably the Pliocene epoch, causing several metres of sea-level rise. However, the structure and long-term evolution of the ice sheet in this region have been understood insufficiently to constrain past ice-sheet extents. Here we show that deep ice-sheet erosion—enough to expose basement rocks—has occurred in two regions: the head of the Totten Glacier, within 150 kilometres of today’s grounding line; and deep within the Sabrina Subglacial Basin, 350-550 kilometres from this grounding line. Our results, based on ICECAP aerogeophysical data, demarcate the marginal zones of two distinct quasi-stable EAIS configurations, corresponding to the ‘modern-scale’ ice sheet (with a marginal zone near the present ice-sheet margin) and the retreated ice sheet (with the marginal zone located far inland). The transitional region of 200-250 kilometres in width is less eroded, suggesting shorter-lived exposure to eroding conditions during repeated retreat-advance events, which are probably driven by ocean-forced instabilities. Representative ice-sheet models indicate that the global sea-level increase resulting from retreat in this sector can be up to 0.9 metres in the modern-scale configuration, and exceeds 2 metres in the retreated configuration.

  17. Resistive magnetohydrodynamic simulations of X-line retreat during magnetic reconnection

    SciTech Connect

    Murphy, N. A.

    2010-11-15

    To investigate the impact of current sheet motion on the reconnection process, we perform resistive magnetohydrodynamic simulations of two closely located reconnection sites that move apart from each other as reconnection develops. This simulation develops less quickly than an otherwise equivalent single perturbation simulation but eventually exhibits a higher reconnection rate. The unobstructed outflow jets are faster and longer than the outflow jets directed toward the magnetic island that forms between the two current sheets. The X-line and flow stagnation point are located near the trailing end of each current sheet very close to the obstructed exit. The speed of X-line retreat ranges from {approx}0.02-0.06, while the speed of stagnation point retreat ranges from {approx}0.03-0.07 in units of the initial upstream Alfven velocity. Early in time, the flow stagnation point is located closer to the center of the current sheet than the X-line, but later on the relative positions of these two points switch. Consequently, late in time, there is significant plasma flow across the X-line in the opposite direction of X-line retreat. Throughout the simulation, the velocity at the X-line does not equal the velocity of the X-line. Motivated by these results, an expression for the rate of X-line retreat is derived in terms of local parameters evaluated at the X-line. This expression shows that X-line retreat is due to both advection by the bulk plasma flow and diffusion of the normal component of the magnetic field.

  18. Diachronous seawater retreat from the southwestern margin of the Tarim Basin in the late Eocene

    NASA Astrophysics Data System (ADS)

    Sun, Jimin; Windley, Brian F.; Zhang, Zhiliang; Fu, Bihong; Li, Shihu

    2016-02-01

    In contrast to the present hyper-arid inland basin surrounded by the high mountains of Central Asia, the western Tarim Basin was once connected with the Tajik Basin at least in the late Eocene, when an epicontinental sea extended from the western Tarim Basin to Europe. Western Tarim is a key site for studying the retreat of seawater, which was likely caused by the northward indentation of the Pamir arc and facilitated by the climatic cooling and eustatic sea level change in the Cenozoic. Here we present a new magnetostratigraphic record from the Tarim Basin that provides evidence of diachronous seawater retreat from its southwestern margin. We studied about 1360 m of well-exposed Eocene-Oligocene strata at Keliyang in the folded foreland of the West Kunlun orogen. Until now, the age of the strata has only been minimally constrained by the presence of late mid-Eocene marine fossils. Our biostratigraphic and magnetostratigraphic results demonstrate that the age of the sedimentary sequence ranges from ∼46 Ma to ∼26 Ma (mid-Eocene to late-Oligocene) and the seawater retreat at Keliyang took place at ∼40 Ma. Considering the stepwise northward indentation and uplift of the Pamir orogen, together with the other previous results, we propose that seawater retreat from the southwestern margin of the Tarim Basin was diachronous in the late Eocene ranging from 47 Ma to 40 Ma. The regional indentation, uplift and erosion of the Pamir orogen played the dominant and important role in controlling the seawater retreat from the southwestern margin of the Tarim Basin.

  19. Slowing down the retreat of the Morteratsch glacier, Switzerland, by artificially produced summer snow

    NASA Astrophysics Data System (ADS)

    Oerlemans, Johannes; Keller, Felix; Haag, Martin

    2017-04-01

    Many large valley glaciers in the world are retreating at historically unprecedented rates. Also in the Alps, where warming over the past decades has been more than twice as large as the global mean, all major glaciers have retreated over distances of several kilometers over the past hundred years. The Morteratsch Glacier, Pontresina, Switzerland, is a major touristic attraction. Due to strong retreat the lowest part of the glacier is getting out of sight from the gravel road that provided direct access to the glacier front. The Community of Pontresina has commissioned a preparatory study to find out if it is possible to slow down the retreat of the Morteratsch Glacier in an environmentally friendly way. In this article we report on the outcome of such a study, based on a modelling approach. Our analysis is based on a 20- year weather station record from the lower part of the glacier, combined with calculations with an ice flow model. This model has been carefully calibrated against the historical glacier length record, to ensure an optimal initial state for projections into the future. We arrive at the conclusion that producing summer snow in the ablation zone over a larger area (typically 0.5 to 1 km ^2) is the best option, and may have a significant effect on the rate of retreat on a timescale of decades. We consider three scenarios of climate change: (i) no change, (ii) a rise of the Equilibrium Line Altitude (ELA) by 1 m/yr, and (iii) a rise of the ELA by 2 m/yr. Projections of glacier length are done until the year 2100. It takes about 10 years before snow deposition in the higher ablation zone starts to affect the position of the glacier snout. The difference in glacier length between the snow and no-snow experiments becomes 400 to 500 m within two decades.

  20. Retreat patterns and dynamics of the Sentralbankrenna glacial system, central Barents Sea

    NASA Astrophysics Data System (ADS)

    Esteves, Mariana; Bjarnadóttir, Lilja R.; Winsborrow, Monica C. M.; Shackleton, Calvin S.; Andreassen, Karin

    2017-08-01

    The Barents Sea Ice Sheet (BSIS) is a good palaeo-analogue for the present day West Antarctic Ice Sheet. Both were marine-based ice sheets, particularly vulnerable to ocean warming and sea-level rise. Understanding the BSIS ice dynamics and patterns of retreat since the Last Glacial Maximum (LGM) is useful in developing our knowledge of spatial and temporal variations during marine-based ice sheet retreat. While the western margins of the Barents Sea have been extensively studied, few studies have focused on the central regions, which hosted key ice stream tributaries and major ice domes and divides. Presenting a new high-resolution (5 m) bathymetric dataset, this glacial geomorphological study focuses on the Sentralbankrenna palaeo-glacial system in the central Barents Sea. A large number of grounding zone wedges, mega-scale glacial lineations and areas with tunnel valleys and palaeo-subglacial basins were identified. These form the basis for a six-stage reconstruction of ice stream retreat through deglaciation since the LGM. In reconstructing the retreat of the Sentralbankrenna Ice Stream, we document the rapid but highly spatially variable pattern of retreat of a marine-based ice sheet margin. The presence of several tunnel valleys and interconnected palaeo-subglacial basin systems indicates an abundance of meltwater, likely to have been stored and released through several discharge events, significantly influencing the ice stream margin dynamics. This study provides insight into the behaviour and dynamics of ice during the late stages of the BSIS deglaciation within the central Barents Sea, increasing our understanding of grounding line processes.

  1. Adjuvant Stereotactic Radiosurgery Reduces Need for Retreatments in Patients with Meningioma Residuals.

    PubMed

    Frostell, Arvid; Hakim, Ramil; Dodoo, Ernest; Sinclair, Georges; Ohlsson, Marcus; Förander, Petter; Milovac, Biljana; Brundin, Lou; Svensson, Mikael

    2016-04-01

    Radical surgical resection of cerebral meningiomas involving the dura mater of venous sinuses is challenging, and tumor residuals are frequently left after surgery. This study sought to evaluate the effect of adjuvant stereotactic radiosurgery (aSRS) on the time to significant growth of meningioma residuals requiring retreatment. A total of 119 consecutive patients (2004-2013) receiving primary surgical treatment for a meningioma in proximity to a venous structure were included. The patients were assessed retrospectively, with a focus on retreatments and mortality. Radicality of initial tumor surgery was scored using postoperative magnetic resonance imaging. Three subgroups were identified: 1) radical total resection (RTR); 2) near-total resection (NTR), followed by aSRS (NTR + aSRS); and 3) NTR but no aSRS (NTR - aSRS). In the NTR - aSRS group, intervention was initiated after radiologic (magnetic resonance imaging) findings verified growth of residual tumor, in contrast to the NTR + aSRS group, which received aSRS before regrowth. Time to first retreatment, progression-free survival (PFS), and overall survival were analyzed with the log-rank test and multiple-events Cox regression. RTR was associated with the best prognosis. The patients in the NTR + aSRS group had significantly longer time to first retreatment compared with NTR - aSRS patients (P < 0.001). There was also a significant difference in mortality (P < 0.05) and a tendency to prolonged PFS (P = 0.07) in the NTR + aSRS group. The Cox regressions confirmed the positive effects of NTR + aSRS on time to retreatment (hazard ratio, 7.3; P < 0.01) and PFS (hazard ratio, 3.69; P = 0.055). aSRS of meningioma residuals had a positive effect on tumor control and should be considered in patients with meningioma residuals. Copyright © 2016 Elsevier Inc. All rights reserved.

  2. Ice stream retreat following the LGM and onset of the west Greenland current in Uummannaq Trough, west Greenland

    NASA Astrophysics Data System (ADS)

    Sheldon, Christina; Jennings, Anne; Andrews, John T.; Ó Cofaigh, Colm; Hogan, Kelly; Dowdeswell, Julian A.; Seidenkrantz, Marit-Solveig

    2016-09-01

    The deglacial history and oceanography of Uummannaq Trough, central West Greenland continental shelf, was investigated using foraminiferal, sedimentological, and bathymetric records together with a radiocarbon chronology, providing a timeline for the retreat of glacial ice after the Last Glacial Maximum (LGM). To map ice stream retreat, data were collected from cores from the outer (JR175-VC45 and JR175-VC43) and inner (JR175-VC42) Uummannaq Trough. A large ice stream, fed by confluent glaciers draining the interior of the Greenland Ice Sheet, extended across the outer shelf during the LGM and was in retreat by 15.0 cal kyr BP. Foraminiferal data indicate that the 'warm' West Greenland Current (WGC) was established prior to 14.0 cal kyr BP, which is the hitherto earliest record of Atlantic Water found on the West Greenland shelf. For each of the cores, foraminifera indicate that ice sheet retreat was followed quickly by incursion of the WGC, suggesting that the warm water may have enhanced ice retreat. Prior to the Younger Dryas cold event, the radiocarbon chronology indicates that the ice sheet retreated to the mid-shelf, where it subsequently stabilised and formed a large grounding-zone wedge (GZW). After the Younger Dryas, around 11.5 cal kyr BP, the ice retreated rapidly from the GZW and into the fjords.

  3. Habitat selection in a rocky landscape: experimentally decoupling the influence of retreat site attributes from that of landscape features.

    PubMed

    Croak, Benjamin M; Pike, David A; Webb, Jonathan K; Shine, Richard

    2012-01-01

    Organisms selecting retreat sites may evaluate not only the quality of the specific shelter, but also the proximity of that site to resources in the surrounding area. Distinguishing between habitat selection at these two spatial scales is complicated by co-variation among microhabitat factors (i.e., the attributes of individual retreat sites often correlate with their proximity to landscape features). Disentangling this co-variation may facilitate the restoration or conservation of threatened systems. To experimentally examine the role of landscape attributes in determining retreat-site quality for saxicolous ectotherms, we deployed 198 identical artificial rocks in open (sun-exposed) sites on sandstone outcrops in southeastern Australia, and recorded faunal usage of those retreat sites over the next 29 months. Several landscape-scale attributes were associated with occupancy of experimental rocks, but different features were important for different species. For example, endangered broad-headed snakes (Hoplocephalus bungaroides) preferred retreat sites close to cliff edges, flat rock spiders (Hemicloea major) preferred small outcrops, and velvet geckos (Oedura lesueurii) preferred rocks close to the cliff edge with higher-than-average sun exposure. Standardized retreat sites can provide robust experimental data on the effects of landscape-scale attributes on retreat site selection, revealing interspecific divergences among sympatric taxa that use similar habitats.

  4. Habitat Selection in a Rocky Landscape: Experimentally Decoupling the Influence of Retreat Site Attributes from That of Landscape Features

    PubMed Central

    Croak, Benjamin M.; Pike, David A.; Webb, Jonathan K.; Shine, Richard

    2012-01-01

    Organisms selecting retreat sites may evaluate not only the quality of the specific shelter, but also the proximity of that site to resources in the surrounding area. Distinguishing between habitat selection at these two spatial scales is complicated by co-variation among microhabitat factors (i.e., the attributes of individual retreat sites often correlate with their proximity to landscape features). Disentangling this co-variation may facilitate the restoration or conservation of threatened systems. To experimentally examine the role of landscape attributes in determining retreat-site quality for saxicolous ectotherms, we deployed 198 identical artificial rocks in open (sun-exposed) sites on sandstone outcrops in southeastern Australia, and recorded faunal usage of those retreat sites over the next 29 months. Several landscape-scale attributes were associated with occupancy of experimental rocks, but different features were important for different species. For example, endangered broad-headed snakes (Hoplocephalus bungaroides) preferred retreat sites close to cliff edges, flat rock spiders (Hemicloea major) preferred small outcrops, and velvet geckos (Oedura lesueurii) preferred rocks close to the cliff edge with higher-than-average sun exposure. Standardized retreat sites can provide robust experimental data on the effects of landscape-scale attributes on retreat site selection, revealing interspecific divergences among sympatric taxa that use similar habitats. PMID:22701592

  5. Changes in Hydrologic Conditions and Greenhouse Gas Emissions in Circumpolar Regions due to Climate Change-Induced Permafrost Retreat

    NASA Astrophysics Data System (ADS)

    Whiticar, M. J.; Bhatti, J.; Startsev, N.

    2011-12-01

    Thawing permafrost peatlands influence northern ecosystems by changing the regional hydrology and mobilizing the vast carbon (C) reserves that results in increased greenhouse gas (GHGs) emissions to the atmosphere. With permafrost distribution controlled largely by topography and climate, our IPY study intensively monitored the local C cycling processes and GHG fluxes associated with different hydrologic and permafrost environments at 4 sites along a climatic gradient extending from the Isolated Patches Permafrost Zone (northern Alberta), to the Continuous Permafrost Zone (Inuvik, NWT). Each site encompasses a local gradient from upland forest and peat plateau to collapse scar. Our multi-year measurements of peatland profiles and flux chambers for CH4 and CO2 concentrations and stable isotope ratios indicate processes, including methanogenesis, methanotrophy, transport and emission that control the distribution of these GHGs. These relationships are modulated by fluctuating local soil water and corresponding ecosystem conditions. The gas geochemistry shows that significant surface CH4 production occurs by both hydrogenotrophic and methyl-fermentative methanogenesis in submerged, anaerobic peats, e.g., collapse scars, whereas methane oxidation is restricted to aerobic, drier environments, e.g., upland sites and peat-atmosphere interface. The most active methanogenesis and emissions are in areas of actively thawing permafrost contrasting with sites under continuous permafrost. This degree of methanogenesis is being amplified by the increased rate of Arctic warming and the rapid retreat of Permafrost in Canada's Arctic (ca. 2.5 km/yr).

  6. Changes in Hydrologic Conditions and Greenhouse Gas Emissions in Circumpolar Regions due to Climate Change-Induced Permafrost Retreat

    NASA Astrophysics Data System (ADS)

    Whiticar, M. J.; Bhatti, J.; Startsev, N.

    2012-12-01

    Thawing permafrost peatlands influence northern ecosystems by changing the regional hydrology and mobilizing the vast carbon (C) reserves that results in increased greenhouse gas (GHGs) emissions to the atmosphere. With permafrost distribution controlled largely by topography and climate, our IPY study intensively monitored the local C cycling processes and GHG fluxes associated with different hydrologic and permafrost environments at 4 sites along a latitudinal climatic gradient of Boreal, Subarctic and Arctic ecoclimatic regions that extend south-north from the Isolated Patches Permafrost Zone (northern Alberta), to the Continuous Permafrost Zone (Inuvik, NWT). Each site encompasses a local hydrologic gradient from upland forest and peat plateau to collapse scar. Our multi-year measurements of peatland profiles and flux chambers for CH4 and CO2 concentrations and stable isotope ratios indicate processes, including methanogenesis, methanotrophy, transport and emission that control the distribution of these GHGs. These relationships are modulated by fluctuating local soil water and corresponding ecosystem conditions. The gas geochemistry shows that significant surface CH4 production occurs by both hydrogenotrophic and methyl-fermentative methanogenesis in submerged, anaerobic peats, e.g., collapse scars, whereas methane oxidation is restricted to aerobic, drier environments, e.g., upland sites and peat-atmosphere interface. The most active methanogenesis and emissions are in areas of actively thawing permafrost contrasting with sites under continuous permafrost. This degree of methanogenesis is being amplified by the increased rate of Arctic warming and the rapid retreat of permafrost in Canada's Arctic (ca. 2.5 km/yr).

  7. Retreatment and Outcomes of Recurrent Intracranial Vertebral Artery Dissecting Aneurysms after Stent Assisted Coiling: A Single Center Experience

    PubMed Central

    Song, Ying; Wang, Yang; Li, Chuanhui; Wang, Yanmin; Mu, Shiqing; Yang, Xinjian

    2014-01-01

    Background and purpose The retreatment of recurrent intracranial vertebral artery dissecting aneurysms (VADAs) after stent assisted coiling (SAC) has not yet been studied. The purpose of this study was to evaluate the strategies and outcomes for retreatment of recurrent VADAs after SAC. Methods Between September 2009 and November 2013, six consecutive patients presenting with recurrent intracranial VADAs after SAC were enrolled in this study. They were all male with age ranging from 29 to 54 years (mean age, 46.2 years). The procedures of treatments and angiographic and clinical follow-up were reviewed retrospectively. Retreatment modalities were selected individually according to the characteristics of recurrence. The outcomes of retreatment were evaluated by angiographic and clinical follow-up. Results Six patients with recurrent intracranial VADAs after SAC were retreated, with second SAC in three patients, coil embolization, double overlapping stents placement and endovascular occlusion with aneurysm trapping in one patient, respectively. Immediate angiographic outcomes of retreatment were: complete occlusion in three patients, nearly complete occlusion in two patients, and contrast medium retention in dissecting aneurysm in one patient. All cases were technically successful. No complications related to endovascular procedures occurred. Angiographic follow-up was available in all five patients treated with second SAC or double overlapping stents, which was complete occlusion in four patients, obliteration of parent artery in one patient, showing no recurrence at 4–11 months (mean: 8.6 months). Clinical follow-up was performed in all six patients at 11–51 months after initial endovascular treatment and at 9–43 months after retreatment. The mRS of last clinical follow-up was excellent in five patients and mild disability in only one patient. Conclusions Endovascular retreatment is feasible and effective for recurrent intracranial VADAs after SAC

  8. Test of a simple glacier retreat parameterization for two Norwegian ice cap glaciers

    NASA Astrophysics Data System (ADS)

    Alesina, Samuel; Beldring, Stein; Melvold, Kjetil; Schaefli, Bettina

    2014-05-01

    In Norway, the ice cap glacier retreat will be an important phenomena under climate change projections and will largely influence water resources.Three new versions of a glacier retreat algorithm based on the parameterization proposed by Huss et al. (2010) are implemented and tested on the Distributed Element Water Model of the Norwegian Water Resources and Energy Directorate. After selection of the best performing algorithm version, the glacier retreat parameters of the model are calibrated on observed discharge and mass balance data for two ice cap glaciers in Norway: Nigardsbreen (maritime glacier) and Midtdalsbreen (semi continental glacier). The calibration performance is acceptable: ice thickness is reproduced with a Root Mean Square Error of 20 respectively 15 m for the two case studies; glacier annual mass balance is overestimated for negative years; daily discharge is reproduced with a Nash Sutcliffe performance criterion between 0.80-0.86 for the period of 1961-1990: Climate change projections are performed for these 2 glaciers using downscaled Regional Climate Models (RCMs) from IPCC A1B emission scenario for greenhouse gases. According to our results, these glaciers are going to decrease dramatically: the ice volume could be reduced by 70 to 80 % in 2100, the annual discharge could increase by 30% till 2070-2080. The annual daily regime can also be assumed to change: the simulation results show that the maximum discharge during summer will decrease whereas winter discharge will increase after a longer recession period in autumn. The beginning of the melting period will not change substantially. The model sensitivity of the applied glacier retreat parameterization (Huss et al. 2010) is analyzed with two approaches: 1/ comparing the ice volume evolution for all Huss parameters sets obtained through calibration in this study to the ones proposed in literature; 2/ varying one parameter after the other keeping the three others fixed. The evolution of the ice

  9. Identifying potential seasonal and historical drivers of marine-terminating glacier retreat in Disko and Uummannaq Bays, West Greenland

    NASA Astrophysics Data System (ADS)

    York, A.; Frey, K. E.; Das, S. B.

    2015-12-01

    The variability in outlet glacier termini positions is an important indicator of overall glacier health and the net effects of ice-ocean-atmosphere interactions. Glacier margins fluctuate on both seasonal and interannual time scales and satellite imagery provides a critical spatially- and temporally-extensive resource for monitoring glacier behavior. Outlet glaciers have generally been retreating globally over recent decades, but the magnitude of seasonal variation, overall retreat, and foremost drivers have proven unique to each glacier. The outlet glaciers in central West Greenland are generally experiencing the same regional atmospheric forcing, yet previous studies have shown varying magnitudes of retreat over the last forty years. In this study, we utilize Landsat imagery between the years 1985 and 2014 to digitize a time series of glacier front positions of 18 marine-terminating outlet glaciers in the Disko and Uummannaq Bay regions of West Greenland. We examine potential drivers of trends in outlet glacier retreat through satellite observations of adjacent sea ice concentrations and sea surface temperatures. Additionally, reanalysis data and long-term automatic weather station measurements are investigated to contextualize the role of atmospheric drivers at both a regional and local scale. Results indicate retreat of all glaciers in the region over the study period and no indication of a south to north trend in magnitude of retreat on either a seasonal or long-term scale. The 11 glaciers in Uummannaq Bay retreated between 25 m and 3.5 km, an average of 1.22 ± 1.20 km over the entire study period. The retreat of 7 glaciers in Disko Bay ranged from 181 m to 2.3 km, an average of 1.0 ± 0.78 km over the period. Although the mean terminus retreat rate between the two bays is comparable, there remains a wide range of total retreat amounts among the glaciers. We investigate the degree of seasonal variation in terminus position as an indicator of longer

  10. Successful retreatment with osimertinib after osimertinib-induced acute pulmonary embolism in a patient with lung adenocarcinoma: A case report.

    PubMed

    Shiroyama, Takayuki; Hayama, Manabu; Satoh, Shingo; Nasu, Shingo; Tanaka, Ayako; Morita, Satomu; Morishita, Naoko; Suzuki, Hidekazu; Okamoto, Norio; Hirashima, Tomonori

    2017-01-01

    Pulmonary embolism (PE) can be life-threatening, and it is challenging to diagnose because of its nonspecific signs and symptoms. PE is also an important potential risk of osimertinib treatment, however, clinical courses regarding retreatment after osimertinib-induced acute pulmonary embolism remain unclear. We described a 77-year-old woman with postoperative recurrent lung adenocarcinoma who developed osimertinib-induced acute PE. She received apixaban and was later successfully retreated with osimertinib. This case suggests that retreatment with osimertinib after osimertinib-induced acute PE may be a treatment option when alternative therapeutic options are limited.

  11. Health-Related Quality of Life in Patients With Locally Advanced Prostate Cancer After 76 Gy Intensity-Modulated Radiotherapy vs. 70 Gy Conformal Radiotherapy in a Prospective and Longitudinal Study

    SciTech Connect

    Lips, Irene Dehnad, Human; Kruger, Arto Boeken; Moorselaar, Jeroen van; Heide, Uulke van; Battermann, Jan; Vulpen, Marco van

    2007-11-01

    Purpose: To compare quality of life (QoL) after 70 Gy conformal radiotherapy with QoL after 76 Gy intensity-modulated radiotherapy (IMRT) in patients with locally advanced prostate carcinoma. Methods and Materials: Seventy-eight patients with locally advanced prostate cancer were treated with 70 Gy three-field conformal radiotherapy, and 92 patients received 76 Gy IMRT with fiducial markers for position verification. Quality of life was measured by RAND-36, the European Organization for Research and Treatment of Cancer core questionnaire (EORTC QLQ-C30(+3)), and the prostate-specific EORTC QLQ-PR25, before radiotherapy (baseline) and 1 month and 6 months after treatment. Quality of life changes in time (baseline vs. 1 month and baseline vs. 6 months) of {>=}10 points were considered clinically relevant. Results: Differences between the treatment groups for QoL changes over time occurred in several QoL domains. The 76-Gy group revealed no significant deterioration in QoL compared with the 70-Gy group. The IMRT 76-Gy group even demonstrated a significantly better change in QoL from baseline to 1 month in several domains. The conformal 70-Gy group revealed temporary deterioration in pain, role functioning, and urinary symptoms; for the IMRT 76-Gy group a better QoL in terms of change in health existed after 1 month, which persisted after 6 months. For both treatment groups temporary deterioration in physical role restriction occurred after 1 month, and an improvement in emotional role restriction occurred after 6 months. Sexual activity was reduced after treatment for both groups and remained decreased after 6 months. Conclusions: Intensity-modulated radiotherapy and accurate position verification seem to provide a possibility to increase the radiation dose for prostate cancer without deterioration in QoL.

  12. LONGITUDINAL SPACE CHARGE EFFECT FOR SNS

    SciTech Connect

    ZHANG,S.Y.; WENG,W.T.

    1998-06-22

    One of performance requirements of the Spallation Neutron Source (SNS) is to keep the uncontrolled beam loss in the storage ring to less than 2 x 10{sup {minus}4} per pulse. For 2 MW SNS, the maximum beam intensity is N = 2 x 10{sup 14} protons per ring. Since the bunch lengthening has impact on both the extraction beam loss and the lowering of e-p instability threshold, the longitudinal space charge effect requires attentions. Such a space charge effect has been studied both analytically and using computer simulations. The longitudinal space charge effect, which is a defocusing force below transition, is a plausible source of the bunch leakage. In this article, the total RF potential, which takes into account the space charge effect together with the RF power, is used to provide analytical predictions for the bunch lengthening. The prediction is confirmed by the computer simulation. It is found that for 2 MW SNS storage ring, the longitudinal space charge induced bunch leakage into the interbunch gap is not significant. Therefore, corrections to the longitudinal space charge impedance, such as the proposed ferrite insertion in the PSR ring, are probably not necessary. Applying an RF voltage ramping from 20 KV to 40 KV during the multiturn injection can further cut the bunch leakage to a negligible degree. The same approach applied to the PSR shows that the longitudinal space charge effect does cause sizable bunch leakage at the intensity limit encountered there.

  13. Glacial Retreat and Associated Glacial Lake Hazards in the High Tien Shan

    NASA Astrophysics Data System (ADS)

    Smith, T. T.

    2013-12-01

    A number of studies have identified glacial retreat throughout the greater Himalayan region over the past few decades, but the Karakorum region remains an anomaly with large stagnating or advancing glaciers. The glacial behavior in the Tien Shan is still unclear, as few studies have investigated mass balances in the region. This study focuses on the highest peaks of the Tien Shan mountain range, in the region of Jengish Chokusu along the Kyrgyzstan-China-Kazakhstan border. In a first step, a 30-year time series of Landsat imagery (n=27) and ASTER imagery (n=10) was developed to track glacial growth and retreat in the region. Using a combination of spectral and topographic information, glacial outlines are automatically delineated. As several important glaciers in the study region contain medium to high levels of debris cover, our algorithm also improves upon current methods of detecting debris-covered glaciers by using topography, distance weighting methods, river networks, and additional spectral data. Linked to glacial retreat are glacial lake outburst floods (GLOFs) that have become increasingly common in High Mountain Asia over the last few decades. As glaciers retreat, their melt water is often trapped by weakly bonded moraines. These moraines have been known to fail due to overtopping caused by surge waves created by avalanches, rockslides, or glacial calving. A suite of studies throughout High Mountain Asia have used remotely-sensed data to monitor the formation and growth of glacial lakes. In a second step of the work, lake-area changes over the past 15 years were tracked monthly and seasonally using dense Landsat/ASTER coverage (n=30) with an automatic procedure based on spectral and topographic information. Previous work has identified GLOFs as a significant process for infrastructural damage in the southern Tien Shan/northern Pamir, as well as in the better studied Himalaya region. Lake identification and quantification of lake-growth rates is a valuable

  14. A Subgrid-Scale Parameterization for Calving-Front Advance and Retreat

    NASA Astrophysics Data System (ADS)

    Albrecht, Torsten

    2010-05-01

    Floating ice shelves fringing most of Antarctica play a key for the flow of ice into the ocean and thereby for global sea level rise. Calving processes at the ice front are highly complex and are often neglected in numerical ice sheet models. Observed accelerated ice discharge after abrupt ice shelf retreat proofs that this is not a viable approach. In order to be able to take ice shelf dynamics into account we have implemented a number of processes into the Potsdam Parallel Ice Sheet Model (PISM-PIK). We present a newly developed subgrid-scale parameterization for calving-front advance and retreat which allows the introduction of stress boundary conditions on the ice-ocean front and thereby a proper computation of the stress and strain field along the calving front. With these improvements we compare different calving rate approaches for different realistic ice shelf geometries (Albrecht et al., J Glac., in prep.).

  15. Contemporary glacier retreat triggers a rapid landslide response, Great Aletsch Glacier, Switzerland

    NASA Astrophysics Data System (ADS)

    Kos, Andrew; Amann, Florian; Strozzi, Tazio; Delaloye, Reynald; Ruette, Jonas; Springman, Sarah

    2016-12-01

    The destabilization and catastrophic failure of landslides triggered by retreating glaciers is an expected outcome of global climate change and poses a significant threat to inhabitants of glaciated mountain valleys around the globe. Of particular importance are the formation of landslide-dammed lakes, outburst floods, and related sediment entrainment. Based on field observations and remote sensing of a deep-seated landslide, located at the present-day terminus of the Great Aletsch Glacier, we show that the spatiotemporal response of the landslide to glacier retreat is rapid, occurring within a decade. Our observations uniquely capture the critical period of increase in slope deformations, onset of failure, and show that measured displacements at the crown and toe regions of the landslide demonstrate a feedback mechanism between glacier ice reduction and response of the entire landslide body. These observations shed new light on the geomorphological processes of landslide response in paraglacial environments, which were previously understood to occur over significantly longer time periods.

  16. Expansion and retreat of the Jura ice sheet (France) during the last glacial maximum

    NASA Astrophysics Data System (ADS)

    Buoncristiani, J. F.; Campy, M.

    2004-03-01

    In continental environments, while there is no uninterrupted record of glaciation, glacier activity can be reconstructed from the nature and geometry of sediments trapped by lake filling. Examination of the Combe d'Ain lake filling provides insight into the history of the Jura Mountains during the last glacial maximum (LGM). From the evidence of outcrops, borehole cores, and seismic reflection profiles of the lake filling, we show that glaciation was marked by three stages of stabilization. Then, recessional moraines marked five episodes of stabilization in the course of glacial retreat. Comparison with ∂ 18O data from ice cores of Greenland makes possible to date the last glacial maximum at 25,500-22,000 Cal. BC and glacial retreat at 22,000-17,000 Cal. BC.

  17. Ecomorphodynamic evolution of salt marshes: Experimental observations of bank retreat processes

    NASA Astrophysics Data System (ADS)

    Francalanci, S.; Bendoni, M.; Rinaldi, M.; Solari, L.

    2013-08-01

    This paper addresses the problem of the erosion of salt marsh edges. Flume laboratory experiments were carried out aimed at reproducing the instability and retreat of the scarps that typically delimit the salt marshes under the attack of wind waves during the tidal cycle. The bank model and hydrodynamic forcing in the flume were such as to simulate the conditions observed in the field in Venice Lagoon. Experiments were conducted for the same hydrodynamic forcing in the case of two identical banks but with and without the inclusion of the vegetation. Experimental results show that bank retreat involves a variety of processes (including particle erosion, cantilever and slide failures). The effect of the vegetation was to produce a delay in the mass failures, related to a certain growth of plant roots, thus providing an overall stabilizing effect. Bank instability was related to the formation of tension cracks at the bank top and to the impulsive effects associated with wave energy dissipation.

  18. A Case of Successful Retreatment of a Maxillary Lateral Incisor with a Supernumerary Root

    PubMed Central

    Aminsobhani, Mohsen

    2015-01-01

    Knowledge about the morphology of the root canal system is a pre-requisite for achieving a successful outcome in root canal treatment. In this report, a patient with a maxillary lateral incisor which had previously undergone orthograde endodontic retreatment for two times is discussed. The tooth had been misdiagnosed with a palatal groove or a root fracture, its prognosis had been determined to be poor and extraction was advised by a practitioner. During our evaluation, an unrecognized supernumerary root and root canal were detected and the tooth was maintained successfully with orthograde endodontic retreatment. The use of cone beam computed tomography (CBCT) and magnification were of significance in the treatment process of this case. PMID:27252762

  19. The tenth annual Ion Channel Retreat, Vancouver, Canada, June 25-27, 2012.

    PubMed

    Kimlicka, Lynn; Jamieson, Ashley Lauren; Liang, Sophia; Brugger, Saranna; Liang, Dong

    2013-05-01

    Ten years after Aurora Biomed (Vancouver, British Columbia, Canada) hosted the inaugural Ion Channel Retreat, this event is recognized as a leading conference for ion channel researchers. Held annually in Vancouver, this meeting consistently provides an outlet for researchers to share their findings while learning about new concepts, methods, and technologies. Researchers use this forum to discuss and debate a spectrum of topics from ion channel research and technology to drug discovery and safety. The Retreat covered key subjects in the ion channel industry, including ion channels as disease targets, transient receptor protein channels as pain and disease targets, ion channels as pain targets, ion channel structure and function, ion channel screening technologies, cardiac safety and toxicology, and cardiac function and pharmacology.

  20. The Tenth Annual Ion Channel Retreat, Vancouver, Canada, June 25–27, 2012

    PubMed Central

    Kimlicka, Lynn; Liang, Sophia; Brugger, Saranna; Liang, Dong

    2013-01-01

    Abstract Ten years after Aurora Biomed (Vancouver, British Columbia, Canada) hosted the inaugural Ion Channel Retreat, this event is recognized as a leading conference for ion channel researchers. Held annually in Vancouver, this meeting consistently provides an outlet for researchers to share their findings while learning about new concepts, methods, and technologies. Researchers use this forum to discuss and debate a spectrum of topics from ion channel research and technology to drug discovery and safety. The Retreat covered key subjects in the ion channel industry, including ion channels as disease targets, transient receptor protein channels as pain and disease targets, ion channels as pain targets, ion channel structure and function, ion channel screening technologies, cardiac safety and toxicology, and cardiac function and pharmacology. PMID:23679851

  1. Endodontic retreatment of a maxillary second molar with three separate buccal roots.

    PubMed

    Jafarzadeh, Hamid; Javidi, Maryam; Zarei, Mina

    2006-12-01

    A rare case of a four-rooted maxillary second molar in a 39-year-old male patient is reported. After clinical and radiographic examination, two separate mesio-buccal roots were detected, and a treatment plan consisting treatment of the mesio-buccal roots and retreatment of the disto-buccal and palatal roots was made to resolve the previous treatment failure. The tooth was treated by orthograde endodontic retreatment in two visits. Mesio-buccal canals that were located in the separate mesio-buccal roots (which were missed in previous treatment) were found and treated. The case report underlines the importance of complete knowledge about root canal morphology and possible variations, coupled with full clinical and radiographic examination, in order to increase the ability of clinicians to treat difficult cases.

  2. Endodontic Retreatment of a Mandibular Second Molar with four Separate Roots: A Case Report.

    PubMed

    Idris, Mohamed; Sakkir, Nasil; Kj, Nandakishore; Kini, Annapurna

    2014-03-01

    Aberrations in the root canal anatomy are a commonly occurring phenomenon. Although the mandibular second molar is commonly a bi-rooted tooth with an uncomplicated endodontic anatomy, variations have to be considered every time endodontic therapy is performed. This case report describes the non-surgical endodontic retreatment performed on a mandibular second molar with four seperate roots and canals. ProTaper Universal rotary nickel-titanium instruments (Dentsply Maillefer, Ballaigues, Switzerland) for treatment and retreatment were used to remove the old gutta percha and to clean and shape all root canals, followed by the complete obturation of root canal system. Post-operative CBCT scan was taken to confirm the quality of the performed treatment.

  3. Endodontic Retreatment of a Mandibular Second Molar with four Separate Roots: A Case Report

    PubMed Central

    Idris, Mohamed; Sakkir, Nasil; KJ, Nandakishore; Kini, Annapurna

    2014-01-01

    Aberrations in the root canal anatomy are a commonly occurring phenomenon. Although the mandibular second molar is commonly a bi-rooted tooth with an uncomplicated endodontic anatomy, variations have to be considered every time endodontic therapy is performed. This case report describes the non-surgical endodontic retreatment performed on a mandibular second molar with four seperate roots and canals. ProTaper Universal rotary nickel-titanium instruments (Dentsply Maillefer, Ballaigues, Switzerland) for treatment and retreatment were used to remove the old gutta percha and to clean and shape all root canals, followed by the complete obturation of root canal system. Post-operative CBCT scan was taken to confirm the quality of the performed treatment. PMID:24783160

  4. Signatures of ice flow, retreat and meltwater delivery in the Gulf of Bothnia

    NASA Astrophysics Data System (ADS)

    Greenwood, Sarah; Clason, Caroline; Nyberg, Johan; Hell, Benjamin; Öiås, Hans; Holmlund, Per; Jakobsson, Martin

    2014-05-01

    The Gulf of Bothnia has variably played host to the main ice divide of the Fennoscandian ice sheet, ice stream onset, trunk and retreat zones, marine ice sheet decay into the large proglacial Baltic Ice Lake, and the subsequent development of an 'inland' marine basin. It is likely to have acted as both source and depocentre for the delivery of ice, water and sediment in both subglacial and ice-marginal domains. These domains and dynamics have been largely inferred from terrestrial, peripheral evidence. The submerged terrain has been little investigated and its glacial geological archives are virtually unknown. In recent years large swathes of high resolution multibeam echo-sounding data (5-10 metre grid cells) from the Baltic Sea and Gulf of Bothnia have been collected for the Swedish Maritime Administration. These data reveal, with unprecedented clarity, glacial landforms associated with the flow and retreat of ice in these basins. Multiple generations of glacial lineations associated with Baltic and Finnish ice streams are resolved, and indicate their shifting geometry and evolving dynamics. Grounding line deposits at a variety of scales allow us to characterise the style and possible rates of retreat. Our data further offer a detailed view of a dynamic subglacial hydrological system on a sediment substrate: its locally varying patterns of incision and sediment deposition, the extent and connectivity of channelised networks, and the intimate relationship between meltwater landforms, ice-marginal deposits and subglacial bedforms. Here we present these data and explore some of their implications for processes of landform creation, large-scale sediment redistribution in the Bothnian and Baltic basins, the coupling between the glacial hydrological system and ice flow/retreat dynamics, and the regional palaeo-ice sheet history.

  5. Building a rheumatology education academy: insights from assessment of needs during a rheumatology division retreat.

    PubMed

    Berman, Jessica R; Aizer, Juliet; Bass, Anne R; Cats-Baril, William L; Parrish, Edward J; Robbins, Laura; Salmon, Jane E; Paget, Stephen A

    2012-06-01

    To implement a rheumatology department education retreat to systematically identify and address the key factors necessary to improve medical education in our division in preparation for developing a rheumatology academy. The Hospital for Special Surgery organized a retreat for the Rheumatology Department aimed at (1) providing formal didactics and (2) assessing participants' self-reported skills and interest in education with the goal of directing this information toward formalizing improvement. In a mixed-methods study design, faculty and fellows in the Division of Rheumatology were surveyed online pre- and post-retreat regarding various aspects of the current education program, their teaching abilities, interest and time spent in teaching, divisional resources allocated, and how education is valued. Enthusiasm for teaching was high before and rose further after the retreat. Confidence in abilities was higher than expected before but fell afterward. Many noted that the lack of specific feedback on teaching skills and useful metrics to assess performance prevented the achievement of educational excellence. Most responding felt lack of time, knowledge of how to teach well, and resources prevented them from making greater commitments to educational endeavors and participating fully and effectively in the department's teaching activities. While most rheumatology faculty members want to improve as teachers, they know neither where their educational strengths and weaknesses lie nor where or how to begin to change their teaching abilities. The key elements for an academy would thus be an educational environment that elevates the quality of teaching throughout the division and promotes teaching careers and education research, and raises the importance and quality of teaching to equivalence with clinical care and research.

  6. Outcome of orthograde retreatment after failed apicoectomy: use of a mineral trioxide aggregate apical plug.

    PubMed

    Mente, Johannes; Leo, Meltem; Michel, Annemarie; Gehrig, Holger; Saure, Daniel; Pfefferle, Thorsten

    2015-05-01

    This controlled, single-center historic cohort study project evaluates treatment outcomes of a nonsurgical treatment approach after failed apicoectomy. The treatment outcomes of nonsurgical retreatment after a failed apicoectomy were evaluated clinically and radiographically. The study cohort consisted of teeth that had received primary root canal treatment and subsequent apicoectomy elsewhere before the patients presented with post-treatment disease. Orthograde retreatment and obturation using an apical mineral trioxide aggregate plug was performed by postgraduate students and endodontic specialists in 25 cases between 2004 and 2012. Pre-, intra-, and postoperative information and the potential effect on the retreatment outcome were evaluated and statistically analyzed using the chi-square test. Twenty-two patients with 23 teeth attended the follow-up examinations (recall rate = 92%). The follow-up periods ranged from 12 to 102 months (median = 35 months). Twenty teeth (87%) were classified as "success," and 3 teeth were considered (17%) "failure." The chi-square test confirmed that the preoperative factor "number of roots" had a statistically significant effect on treatment outcome (odds ratio = 0.08; 95% confidence interval, 0-1.76; P = .03). The factor "tooth location" was of borderline significance (odds ratio = 0.1; 95% confidence interval, 0-2.14; P = .05). The results of the present study suggest that orthograde retreatment combined with orthograde placement of an apical mineral trioxide aggregate plug is a promising long-term treatment option for teeth with postsurgical pathosis. The success rates were higher for single-rooted teeth. The use of cone-beam computed tomographic imaging in cases of inconclusive periapical radiographs is recommended to minimize the risk of misinterpretation when assessing treatment outcome. Copyright © 2015 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  7. Retreatment with teriparatide: our experience in three patients with severe secondary osteoporosis.

    PubMed

    Mana, D L; Zanchetta, M B; Zanchetta, J R

    2016-12-14

    Teriparatide is a drug for the treatment of osteoporosis which is licensed for use for up to 24 months. There is little experience with retreatment. The aim of this study was to evaluate, in three patients with severe secondary osteoporosis, the response to a second cycle of teriparatide regarding bone mineral density (BMD) and osteocalcin. Case 1 : A 62-year-old woman with multiple vertebral fractures has received corticoids for a long time. After starting teriparatide, her BMD and osteocalcin increased. She then received ibandronate for 3 years but her BMD declined. After a second treatment with teriparatide, her BMD increased again (18%). Case 2 : A 60-year-old woman with severe osteoporosis in lumbar spine (LS) (T-score - 4.5) had received corticoids for a long time and had celiac disease. After starting teriparatide, her BMD improved by 11.7%. She then received zoledronic acid for 15 months, but bone density decreased, so she was retreated with teriparatide. BMD had a slightly higher increase than after the first cycle (12.6%). Case 3 : A 60-year-old woman consulted for osteoporosis (LS T-score - 5.3), several fractures, and hyperthyroidism. She started teriparatide with improvement in BMD (39%). After 24 months, she received ibandronate for 1 year, but as her BMD declined, she was retreated with teriparatide. BMD showed an increase of 15%. The indication of a second cycle of treatment with teriparatide in three patients was effective in increasing BMD. Additional studies are needed to further identify the benefits and safety of retreatment with teriparatide.

  8. Projections of grounding line retreat in West Antarctica carried out with an adaptive mesh model

    NASA Astrophysics Data System (ADS)

    Cornford, Stephen; Payne, Antony; Martin, Daniel; Le Brocq, Anne

    2013-04-01

    Present and future sea level rise associated with mass loss from West Antarctica is typically attributed to marine glaciers retreating in response to a warming ocean. Warmer waters melt the floating ice shelves that restrain some, if not all, marine glaciers, and the glaciers themselves respond by speeding up. That leads to thinning and in turn grounding line retreat. Satellite observations indicate that Amundsen Sea Embayment and, in particular, Pine Island Glacier, are undergoing this kind of dynamic change today. Numerical models, however, struggle to reproduce the observed behavior because either high resolution or some other kind special treatment is required at the grounding line. We present 200-year projections of three major glacier systems of West Antarctica: those that drain into the Amundsen Sea , the Filchner-Ronne Ice Shelf and the Ross Ice shelf. We do so using the newly developed BISICLES ice­ sheet model, which employs adaptive ­mesh refinement to maintain sub-kilometer resolution close to the grounding line and coarser resolution elsewhere. Ice accumulation and ice­ shelf melt-rate are derived from a range of models of the Antarctic atmosphere and ocean forced by the SRES A1B and E1 scenarios. We find that a substantial proportion of the grounding line in West Antarctica retreats, however the total sea level rise is less than 50 mm by 2100, and less than 100 mm by 2200. The lion's share of the mass loss is attributed to Pine Island Glacier, while its immediate neighbor Thwaites Glacier does not retreat until the end of the simulations.

  9. Local Recurrence After Primary Proton Beam Therapy in Uveal Melanoma: Risk Factors, Retreatment Approaches, and Outcome.

    PubMed

    Seibel, Ira; Cordini, Dino; Rehak, Matus; Hager, Annette; Riechardt, Aline I; Böker, Alexander; Heufelder, Jens; Weber, Andreas; Gollrad, Johannes; Besserer, Angela; Joussen, Antonia M

    2015-10-01

    To evaluate the risk factors, recurrence rates, retreatments, and long-term patient outcomes following proton beam therapy for uveal melanoma. Retrospective interventional case series. All patients treated with primary proton beam therapy for uveal melanoma at the oncology service at Charité-Berlin and Helmholtz-Zentrum-Berlin between May 1998 and December 2008 were reviewed for local recurrence. Of 982 patients, 982 eyes matched the inclusion criteria. The data were obtained from electronic health records, operative reports, discharge letters, and radiation planning. Comparisons of fundus photographs and ultrasound measurements were performed to assess the growth pattern of the tumor and to determine the success of retreatment, in the case that a globe-retaining therapy was undertaken. Of 982 patients, 35 patients (3.6%) developed local recurrence. The median follow-up was 60.7 months (6.0-170.4 months). Local control rate was 96.4% and the overall eye retention rate was 95.0% in this cohort. Local recurrence was correlated with a higher risk for metastasis and reduced survival. Largest tumor diameter was identified as the sole statistically significant risk factor for local recurrence (P = .00001). All globe-retaining retreatment approaches for local recurrence, including proton beam therapy, brachytherapy, and transpupillary thermotherapy used for recurrences at the tumor margins, showed good local tumor control and similar metastasis-free survivals. This study showed that each globe-retaining retreatment approach can result in satisfying local tumor control. In case of early detection of local recurrence, preservation of the globe can be warranted. Therefore, regularly performed follow-ups should be ensured. Copyright © 2015 Elsevier Inc. All rights reserved.

  10. Treatment and retreatment of a patient with a severe anterior open bite.

    PubMed

    Bosio, Jose A; Justus, Roberto

    2013-10-01

    An 8-mm anterior and posterior open bite caused by a tongue rest posture habit was closed in a 25-year-old man by means of mandibular soldered tongue spurs and without orthognathic surgery. All maxillary and mandibular first molars were extracted, and the spaces were closed. Inappropriate retention protocol allowed for relapse in a 6-month period. A new 1-year orthodontic retreatment was conducted; after an appropriate retention protocol, the outcomes of treatment were significantly improved.

  11. A complex deglacial retreat history of the Anvers Island Trough paleo-ice stream

    NASA Astrophysics Data System (ADS)

    Shevenell, A.; Ishman, S. E.; Domack, E. W.; Leventer, A.; Rosenheim, B. E.; Vadman, K. J.

    2015-12-01

    Marine-terminating ice regulates the mass balance and stability of Antarctica's ice sheets and, ultimately, global sea level. However, predictions of future ice sheet response to climate change are limited by short observational time-series and the complexity of associated forcings and feedbacks. Here, we present new chronologic and multiproxy data from 7 marine sediment records from the outer to inner shelf down the axis of the Anvers Island Trough and into Palmer Deep that better constrain the timing and rate of ice retreat and improve understanding of the mechanisms driving deglaciation of this hypothesized paleo-ice stream. The retreat chronology is based on 16 CaCO3 (foraminifer and mollusk) and 45 ramped pyrolysis (acid-insoluble organic matter) AMS 14C dates. Radiocarbon dates from the laminated diatom ooze and mud facies immediately above the glacial diamicton indicate that deglaciation of the mid-Anvers Island Trough post-dated the Palmer Deep deglaciation by ~2000 uncorrected 14C years and that collapse of the mid-shelf system was rapid, if not instantaneous. The laminated facies, present throughout the suite of cores, is consistent with the calving bay reentrant model for deglaciation. However, this facies is limited (~15 couplets) on the mid-shelf and expanded (~127 couplets) on the inner-shelf, suggesting regional differences in calving bay duration. Planktic and benthic foraminifer isotopes, together with foraminifer and diatom assemblages, and biogeochemical data provide evidence for the presence of warmer nutrient-rich modified Circumpolar Deep Water throughout the Anvers Island Trough during deglaciation. The observed retreat complexity may relate to a hypothesized mid-shelf ice-dome system and requires additional geological and geophysical data to understand ice retreat patterns south and west of Palmer Deep. Such data will provide important new constraints for ice sheet models.

  12. Toward a Predictive Model of Arctic Coastal Retreat in a Warming Climate, Beaufort Sea, Alaska

    DTIC Science & Technology

    2012-09-30

    quantify the environmental drivers of rapid coastal erosion in the Arctic, and to begin developing predictive models of future rates of coastal erosion ...wave) energy in driving coastal erosion in the Arctic. We are combining high-resolution observations of coastline retreat with meteorological and...content, ice-wedge polygon spacing, and the thermal properties of bluff materials; 2) time-lapse photography to observe coastal erosion processes in

  13. Irregular tropical glacier retreat over the Holocene epoch driven by progressive warming.

    PubMed

    Jomelli, Vincent; Khodri, Myriam; Favier, Vincent; Brunstein, Daniel; Ledru, Marie-Pierre; Wagnon, Patrick; Blard, Pierre-Henri; Sicart, Jean-Emmanuel; Braucher, Régis; Grancher, Delphine; Bourlès, Didier Louis; Braconnot, Pascale; Vuille, Mathias

    2011-06-08

    The causes and timing of tropical glacier fluctuations during the Holocene epoch (10,000 years ago to present) are poorly understood. Yet constraining their sensitivity to changes in climate is important, as these glaciers are both sensitive indicators of climate change and serve as water reservoirs for highland regions. Studies have so far documented extra-tropical glacier fluctuations, but in the tropics, glacier-climate relationships are insufficiently understood. Here we present a (10)Be chronology for the past 11,000 years (11 kyr), using 57 moraines from the Bolivian Telata glacier (in the Cordillera Real mountain range). This chronology indicates that Telata glacier retreated irregularly. A rapid and strong melting from the maximum extent occurred from 10.8 ± 0.9 to 8.5 ± 0.4 kyr ago, followed by a slower retreat until the Little Ice Age, about 200 years ago. A dramatic increase in the rate of retreat occurred over the twentieth century. A glacier-climate model indicates that, relative to modern climate, annual mean temperature for the Telata glacier region was -3.3 ± 0.8 °C cooler at 11 kyr ago and remained -2.1 ± 0.8 °C cooler until the end of the Little Ice Age. We suggest that long-term warming of the eastern tropical Pacific and increased atmospheric temperature in response to enhanced austral summer insolation were the main drivers for the long-term Holocene retreat of glaciers in the southern tropics.

  14. Climate change and glacier retreat from 1955 to 2006 on Cilo Mountains, Southeast Anatolia, Turkey

    NASA Astrophysics Data System (ADS)

    Yeşilyurt, Serdar; Uǧur, Doǧan; Kılar, Hatice

    2013-04-01

    Alpine glaciers are amongst key indicators of global-scale climate changes because of their natural dynamics and quick response to global warming. Although there is vast number of studies on recent glaciers of the world, less attention has been paid to the glaciers of Turkey and the Middle East. In the present study, present glaciers of Cilo Mountains (4135 m) located in Southeast Anatolia, one of the most important recent glacier areas of Turkey, is dealt with within the context of the impacts of climatic changes on glaciers. Based on aerial photographs taken in 1955, 1968 and 1988 together with Quickbird satellite images taken in 2006, four main stages were examined using remote sensing and GIS technologies. The paleo-glacier cover of the Last Glacial age (most likely the Last Glacial Maximum) on the Cilo Range was about 100 km² in area as compared to the actual glaciers found in the three valley system around Uludoruk summit with an area of only 5.6 km². Actual glacier have retreated between 100 and 360 m in the period from 1955 to 2006. According to elevation, thickness-mass characteristics of the glaciers and geomorphic conditions of their cirques, retreat rates were found to be between 2 and 7 m/yr. The ages of young terminal moraines were also calculated on the basis of annual decline rates of these glaciers. Consequently, the oldest moraines should have probably been deposited between 1850 and 1870 matching end of the Little Ice Age. This age is compatible with the glacier retreat of the European Alps. We determined a warming trend both in summer temperatures and annual averages based on data from three meteorological stations located in the vicinity of this mountain area. Keywords: Cilo Mountains, actual glacier, glacier retreat, climate change, Little Ace Age, Turkey

  15. Hydrologically-induced slow-down as a mechanism for tidewater glacier retreat

    NASA Astrophysics Data System (ADS)

    Hewitt, Ian

    2017-04-01

    Outlet glaciers flowing into the ocean often terminate at a calving front, whose position is sensitively determined by the balance between ice discharge and calving/terminus-melting. Rapid retreat of tidewater glaciers can be initiated when the front is perturbed from a preferred pinning point, particularly when the glacier sits in an overdeepened trough. This is believed to make certain areas of ice sheets particularly vulnerable to ice loss. A number of factors may cause a previously stable front position to become unstable, including changes in buttressing provided by an ice shelf, and changes in ocean temperature. Another possibility is that initial retreat is induced by a reduction in the supply of ice from the interior of the ice sheet. Such a reduction can naturally arise from an increase in surface melting and runoff (in the absence of accumulation changes), and this may be amplified if more efficient meltwater routing reduces basal lubrication, as has been observed in some areas of the Greenland ice sheet. Since the initiation of rapid retreat often results in an increase of ice discharge at the front (due to increased ice thickness), such a process may not be easy to detect. In this study, I employ a simplified model of an outlet glacier and its frontal behaviour to examine the extent to which hydrologically induced slow-down of the feeding ice sheet may induce (or help to induce) calving front retreat. The model builds on earlier parameterisations of grounding line fluxes, and assumes that calving occurs according to a criterion that keeps the front close to the flotation thickness. The glacier bed is assumed to be plastic. This allows for a transparent identification of the different forcing terms affecting margin position. We conclude that hydrologically-induced slow-down of ice sheets is likely to have a more significant effect on mass loss than hydrologically-induced speed-up.

  16. Processes controlling the retreat of the Isles Dernieres, a Louisiana barrier-island chain

    USGS Publications Warehouse

    Dingler, John R.; Reiss, Thomas E.

    1991-01-01

    The Isles Dernieres is a low-lying, transgressive barrier-island chain situated about 150 km west of the modern Mississippi delta. Much of the Isles Dernieres consists of highly dissected salt-marsh muds that lie at or slightly above sea level and are covered by a veneer of sand along the shoreline facing the Gulf of Mexico. Maximum berm elevations are generally less than 1.5 m above mean sea level. Since the mid-1800s, the initial island has been fragmented into four islands, and the beach face has retreated landward at a rate of more than 10 m/yr. The dominant processes controlling degradation of the chain are cold fronts that pass through the area several times each year and occasional hurricanes. Beach surveys over a 2-year period on the Isles Dernieres document irreversible beach-face retreat in conjunction with multiple cold fronts and one major hurricane (Gilbert). Although both the hurricane and the cold fronts caused the island to erode, the erosional patterns of the two storm types differed from each other. During the two years, over 60 cold fronts collectively caused about 37 m of beach-face retreat, whereas Gilbert itself produced more than 40 m of retreat. A major difference between the two storm types was in the percentage of washover sand produced by each. Commonly, the cold fronts did not create enough of a storm surge to overtop the berm, so most of the material removed from the beach face must have moved offshore or alongshore. Gilbert, in contrast, inundated the study site, and essentially all the sand removed from the beach face moved to the backshore.

  17. Millennial Rates of Sea Cliff Retreat Derived From Cosmogenic 10Be and Coastal Platform Morphology

    NASA Astrophysics Data System (ADS)

    Hurst, M. D.; Ellis, M. A.; Rood, D. H.

    2014-12-01

    Observation of cliff erosion are often limited to relatively short timescales (a few decades), which are within the timeframe of anthropogenic modification of the coast and may be shorter than the recurrence interval for erosion events. Here we present long-term (centennial-millennial) averaged rates of sea cliff retreat for chalk cliffs in SE England derived from cosmogenic isotopes and coastal morphology. We determine long-term rates of sea cliff erosion from 10Be measured from in situ flint samples collected from three transects across the coastal platform in East Sussex. A numerical model of 10Be accumulation on an evolving coastal profile allows estimation of cliff retreat rate averaged over several hundred years. The model accounts for variation in 10Be accumulation with tides and sea-level rise, and takes into account platform downwear and topographic shielding by adjacent cliffs. Additionally, we use high-resolution (1m) multibeam bathymetry to map the extent of the coastal platform based on the surface texture in order to infer the position of the coast at ~8 ka. The difference in position to the current coastline provides estimates of Holocene-averaged rates of cliff erosion for all chalk cliffed coastline in the region. Comparison to historic records of cliff retreat reveals key similarities and differences between long and short-term signals. In certain locations, there are significant discrepancies (either faster or slower) between historic records and long-term rates of retreat. Each type of discrepancy may be the result of human interaction with the coastal environment, whether that interaction is local or non-local, and it is worthwhile noting that sites of relatively low historic rates of erosion are likely subject to high-magnitude, low-frequency failure events that could have devastating effects on human lives and infrastructure in areas that are considered to be low risk.

  18. On optimal retreat distance for the equivalent source method-based nearfield acoustical holography.

    PubMed

    Bai, Mingsian R; Chen, Ching-Cheng; Lin, Jia-Hong

    2011-03-01

    As a basic form of the equivalent source method (ESM) that is used to nearfield acoustical holography (NAH) problems, discrete monopoles are utilized to represent the sound field of interest. When setting up the virtual source distribution, it is vital to maintain a "retreat distance" between the virtual sources and the actual source surface such that reconstruction would not suffer from singularity problems. However, one cannot increase the distance without bound because of the ill-posedness inherent in the reconstruction process with large distance. In prior research, 1-2 times lattice spacing, or the inter-element distance of microphones, is generally recommended as retreat distance in using the ESM-based NAH. While this rule has shown to yield good results in many cases, the optimal choice is a complicated issue that depends on frequency, geometry of the physical source, content of evanescent waves, distribution of sensors and virtual sources, etc. This paper deals about attaining the best compromise between the reconstruction errors induced by the point source singularity; the reconstruction ill-posedness is an interesting problem in its own right. The paper revisits this issue, with the aid of an optimization algorithm based on the golden section search and parabolic interpolation. Numerical simulations were conducted for a baffled planar piston source and a spherically baffled piston source. The results revealed that the retreat distance appropriate for the ESM ranged from 0.4 to 0.5 times the spacing for the planar piston, while from 0.8 to 1.7 times average spacing for the spherical piston. Experiments carried out for a vibrating aluminum plate also revealed that the retreat distance with 0.5 times the spacing yielded better reconstructed velocity than those with 1/20 and 1 times the spacing.

  19. Endodontic retreatment: clinical comparison of reciprocating systems versus rotary system in disinfecting root canals.

    PubMed

    Martinho, Frederico C; Freitas, Lilian F; Nascimento, Gustavo G; Fernandes, Aleteia M; Leite, Fabio R M; Gomes, Ana P M; Camões, Izabel C G

    2015-07-01

    This clinical study was conducted to compare the effectiveness of single-file reciprocating systems and rotary systems in removing endotoxins and cultivable bacteria in endodontic retreatment. Thirty endodontically treated teeth with post-treatment apical periodontitis were selected. The specimens were divided into three groups according to the system used: WaveOne (n = 10), Reciproc instrument (n = 10), and ProTaper Universal Retreatment system (n = 10). Samples were collected before and after chemomechanical preparation. The irrigation was performed by using 2.5% sodium hypochlorite. A chromogenic limulus amebocyte lysate assay test was used to quantify endotoxins. Culture techniques were used to determine bacterial colony-forming unit counts. At baseline, endotoxins and cultivable bacteria were recovered from 100% of the root canal samples in a median value of 5.84 EU/mL and 4.98 × 10(3) CFU/mL, respectively. After CMP, no differences were found in the median percentage values of endotoxin reduction achieved with reciprocating systems-WaveOne [94.11%] and Reciproc [93.29%] and with rotary systems-ProTaper [94.98%] (P > 0.05). Both single-file reciprocating systems [WaveOne (98.27%) and Reciproc (99.54%)] and rotary system [ProTaper (98.73%)] were effective in reducing bacterial load (P > 0.05). Moreover, no differences were found among the systems tested. The Reciproc and WaveOne reciprocating systems were as effective as the ProTaper system for removal of endotoxins and bacteria in endodontic retreatment. All systems tested were effective to remove cultivable bacteria and endotoxin in endodontic retreatment. As no differences among systems were observed, it is possible to suggest that clinicians should choose the preferred technique to perform endodontic.

  20. Nonsurgical endodontic retreatment of a mandibular first molar with five canals: 1-year follow-up.

    PubMed

    Parekh, Deepak J; R, Sathyanarayanan

    2012-03-01

    Mandibular first molars have highly variable root canal morphology. According to previous studies, the occurrence of middle mesial canals ranges from 1% to 15%. In this case, nonsurgical endodontic retreatment of a mandibular first molar with a middle mesial canal is attempted. The authors describe the diagnosis and clinical management of a mandibular first molar with three mesial root canals, drawing particular attention to radiographic interpretation and access refinements.

  1. Past ice-sheet behaviour: retreat scenarios and changing controls in the Ross Sea, Antarctica

    NASA Astrophysics Data System (ADS)

    Halberstadt, Anna Ruth W.; Simkins, Lauren M.; Greenwood, Sarah L.; Anderson, John B.

    2016-05-01

    Studying the history of ice-sheet behaviour in the Ross Sea, Antarctica's largest drainage basin can improve our understanding of patterns and controls on marine-based ice-sheet dynamics and provide constraints for numerical ice-sheet models. Newly collected high-resolution multibeam bathymetry data, combined with two decades of legacy multibeam and seismic data, are used to map glacial landforms and reconstruct palaeo ice-sheet drainage. During the Last Glacial Maximum, grounded ice reached the continental shelf edge in the eastern but not western Ross Sea. Recessional geomorphic features in the western Ross Sea indicate virtually continuous back-stepping of the ice-sheet grounding line. In the eastern Ross Sea, well-preserved linear features and a lack of small-scale recessional landforms signify rapid lift-off of grounded ice from the bed. Physiography exerted a first-order control on regional ice behaviour, while sea floor geology played an important subsidiary role. Previously published deglacial scenarios for Ross Sea are based on low-spatial-resolution marine data or terrestrial observations; however, this study uses high-resolution basin-wide geomorphology to constrain grounding-line retreat on the continental shelf. Our analysis of retreat patterns suggests that (1) retreat from the western Ross Sea was complex due to strong physiographic controls on ice-sheet drainage; (2) retreat was asynchronous across the Ross Sea and between troughs; (3) the eastern Ross Sea largely deglaciated prior to the western Ross Sea following the formation of a large grounding-line embayment over Whales Deep; and (4) our glacial geomorphic reconstruction converges with recent numerical models that call for significant and complex East Antarctic ice sheet and West Antarctic ice sheet contributions to the ice flow in the Ross Sea.

  2. Ecosystem response to a temporary sea ice retreat in the Bering Sea: Winter 2009

    NASA Astrophysics Data System (ADS)

    Miksis-Olds, Jennifer L.; Stabeno, Phyllis J.; Napp, Jeffery M.; Pinchuk, Alexei I.; Nystuen, Jeffrey A.; Warren, Joseph D.; Denes, Samuel L.

    2013-04-01

    Adding acoustic systems onto ocean moorings and observatories provides additional data to more fully document ecosystem responses to environmental perturbations. A passive acoustic recorder and three-frequency echosounder system were integrated into a biophysical mooring on the central eastern Bering Sea continental shelf. An unexpected, transient, mid-winter retreat of the seasonal sea ice was observed over the mooring for a 2-week period in March 2009. Interpretation of the passive acoustic data provided information about sea ice conditions and included the detection and identification of vocalizing marine mammals, while the acoustic backscatter provided information on relative zooplankton and fish abundance before, during, and after the retreat. Hydrographic data confirmed the acoustic signal was associated with changing surface ice conditions, and the combined information from the biophysical mooring sensors revealed changes in winter trophic level dynamics during the retreat, which would have otherwise been undetected by traditional ship-based observations. Changes in the acoustic environment, zooplankton dynamics, and acoustic detection of marine mammals were observed amidst a physically stable and uniform water column with no indication of a phytoplankton bloom. These data demonstrate the value of acoustic technologies to monitor changing ecosystems dynamics in remote and hazardous locations.

  3. Investigation of cultivable bacteria isolated from longstanding retreatment-resistant lesions of teeth with apical periodontitis.

    PubMed

    Signoretti, Fernanda G C; Gomes, Brenda P F A; Montagner, Francisco; Jacinto, Rogério C

    2013-10-01

    The objective of this research was to investigate the presence of viable bacteria in tissue samples from persistent apical lesions and to correlate the microbiological findings with the histopathological diagnosis of the lesion. Twenty persistent apical lesions associated with well-performed endodontic retreatment were collected. Tissue samples were processed through culture techniques including serial dilution, plating, aerobic and anaerobic incubation, and biochemical tests for microbial identification followed by histopathological diagnosis. Cysts were more frequently diagnosed (13/20). Strict anaerobic species predominated in both cysts (80.4% of the species detected) and granulomas (65% of the species detected). Viable gram-positive bacteria were frequently recovered from apical lesions (cysts = 70.6%, granulomas = 84.4%). Gemella morbillorum and Propionibacterium acnes were the most frequently recovered species from cysts and granulomas, respectively. At least 1 gram-positive bacterial species was present in almost every sample (cysts = 12/13, granulomas = 7/7). No significant correlation was found between histologic findings and bacterial species. In conclusion, although cysts were more frequent than granulomas in cases of failure of endodontic retreatment, bacteria were isolated from both types of lesions, with a predominance of gram-positive species, suggesting that these species can survive outside the root canal and might be related to the persistence of the pathological process even after accurate endodontic retreatment. Copyright © 2013 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  4. 10Be history of cliff retreat: theory and example from the English Channel

    NASA Astrophysics Data System (ADS)

    Regard, Vincent; Dewez, Thomas; Bourlès, Didier; Duperret, Anne; Costa, Stéphane; Leanni, Laetitia; Lasseur, Eric; Pedoja, Kevin; Maillet, Grégoire

    2010-05-01

    What if coastal cliffs recession rates could be measured 60 times further in time than with classical methods? Coastal cliff evolution prediction for the next century would then not be so much of a stretch. In this work, we present a new method based on measurements and modelling of 10Be concentration transect across present-day shore platforms to establish the recession rate of coastal cliff for the last ca. 6000 years. The numerical model predicts the shape of 10Be concentration transects to be expected as a function of a given cliff recession rate, vertical coastal platform down-wearing rate and assumed time of sea level reestablishment to present-day level since deglaciation. Two independent transect features serve to fit long-term recession rate model to field observations: a major 10Be concentration drop is predicted where the cliff was abandoned for ca. 100k years, during the glacial period, and a characteristic dome shape directly related to the recession rate of the cliff. A retreating cliff site from the English Channel coast of France at Mesnil Val serves as a demonstrator of this method. Retreat rates were too fast to pinpoint the predicted glacial cliff position but 10Be concentrations sampled across the shore platform nevertheless indicate that the cliff retreat rate since the mid-late Holocene is comprised between 10-30 cm/yr, with a preferred value at 25 ± 5 cm, which turns out to be fully coherent with a 30-years-long assessment.

  5. Interest in health promotion among Korean American Seventh-day Adventists attending a religious retreat.

    PubMed

    Jo, Angela M; Maxwell, Annette E; Choi, Sunhye; Bastani, Roshan

    2012-01-01

    Little is known about interest in faith-based health promotion programs among Asian American populations. Among the Christian denominations, the Seventh-day Adventist (SDA) church is known to place a strong doctrinal emphasis on health. To understand appropriate ways to develop and implement health promotion programs and to conduct research among Korean American SDAs. We collaborated with the North American Division of Korean SDA Churches which sponsors annual week-long religious retreats for their church members. We developed and administered a 10-page questionnaire at their 2009 retreat in order to assess socio-demographic and church characteristics, religiosity, perceived relationship between health and religion, and interest and preferences for church-based health promotion programs. Overall, 223 participants completed our survey (123 in Korean and 100 in English). The sample consisted of regular churchgoers who were involved in a variety of helping activities, and many holding leadership positions in their home churches. The vast majority was interested in receiving health information at church (80%) in the form of seminars, cooking classes and workshops (50-60%). Fewer respondents were interested in support groups (27%). Some interests and preferences differed between English and Korean language groups. Korean American SDA church retreat participants from a large geographic area are very interested in receiving health information and promoting health at their churches and can potentially serve as "agents of influence" in their respective communities.

  6. High space-time resolution analysis of ice motion at a rapidly retreating tidewater glacier (Invited)

    NASA Astrophysics Data System (ADS)

    Oneel, S.; Joughin, I. R.; March, R. S.; Burgess, E. W.; Welty, E.; Pfeffer, W. T.; Larsen, C. F.

    2013-12-01

    Rapid changes to rates of sea level rise are forced in large part by tidewater glacier dynamics. Alaska's Columbia Glacier is an iconic example; in recent years, calving losses account for roughly 20% of the net mass loss from the entire Alaska region. In turn, the Alaska region accounts for ~20% of global new-water sea-level rise. To better understand the mechanics of rapid tidewater glacier mass loss, we present and analyze surface elevation and velocity data acquired at high time resolution since fall 2011. Strong seasonality in flow speed exists, with more than a doubling of near-terminus speed occurring between summer and winter. The imagery provides unprecedented spatial coverage, demonstrating spatial coherence in flow variability across most, but not all, tributaries. Preliminary calculations of ice flux also show strong seasonality, with variable year-to-year timing of peak discharge. Compared to previous estimates, the average flux in this most recent interval is reduced by ~30-40%. An additional overdeepening is located upstream from the present-day terminus, indicating another episode of increased flux is possible. However, total glacier volume has been reduced by ~50% during the retreat, and peak discharge from Columbia has likely already occurred. Our analysis suggests that, as the Columbia Glacier retreat comes to a conclusion, rates of mass loss from the Alaska region will decrease in the near-future, unless another tidewater glacier enters rapid retreat.

  7. Diachronous retreat of the Greenland ice sheet during the last deglaciation

    NASA Astrophysics Data System (ADS)

    Sinclair, G.; Carlson, A. E.; Mix, A. C.; Lecavalier, B. S.; Milne, G.; Mathias, A.; Buizert, C.; DeConto, R.

    2016-08-01

    The last deglaciation is the most recent interval of large-scale climate change that drove the Greenland ice sheet from continental shelf to within its present extent. Here, we use a database of 645 published 10Be ages from Greenland to document the spatial and temporal patterns of retreat of the Greenland ice sheet during the last deglaciation. Following initial retreat of its marine margins, most land-based deglaciation occurred in Greenland following the end of the Younger Dryas cold period (12.9-11.7 ka). However, deglaciation in east Greenland peaked significantly earlier (13.0-11.5 ka) than that in south Greenland (11.0-10 ka) or west Greenland (10.5-7.0 ka). The terrestrial deglaciation of east and south Greenland coincide with adjacent ocean warming. 14C ages and a recent ice-sheet model reconstruction do not capture this progression of terrestrial deglacial ages from east to west Greenland, showing deglaciation occurring later than observed in 10Be ages. This model-data misfit likely reflects the absence of realistic ice-ocean interactions. We suggest that oceanic changes may have played an important role in driving the spatial-temporal ice-retreat pattern evident in the 10Be data.

  8. Title: Climate-glacier Relationship of Retreating Alaskan Glaciers Author: Elliott Mazur and Umesh K. Haritashya

    NASA Astrophysics Data System (ADS)

    Mazur, E. M.

    2012-12-01

    Portage, Whittier, Eklutna, as well as many other well-known "tourism glaciers" in the vicinity of Anchorage, Alaska are known to have retreated in the past 20 years. This begs the question, "what of the other lesser-known glaciers? Do they follow the same patterns and minimal glacier models?" Glaciers such as Byron, Leonard, Matanuska, Raven and Spencer may fit a minimal model. Information on Byron and Leonard is sparse, as both have become hanging glaciers. Other glaciers, such as Raven, are small enough to be deemed insignificant, yet may have information to give. Consequently our objective is to study five Alaskan glaciers and determine wide-ranging variability to changing regional climate. To do this we obtained field geo-location data and characterized glaciers based on the satellite imagery and climate reevaluation. Our result shows that glaciers are retreating and thinning irrespective of their aspects, location and altitudinal variability. Moreover, our presentation establishes the strong climate-glacier relationship and defines retreating snowline patterns over the last few decades.

  9. Historic and Contemporary Shoreline Retreat Rates at the Community of Goodnews Bay, Alaska

    NASA Astrophysics Data System (ADS)

    Buzard, R.; Maio, C. V.; Kinsman, N.

    2016-12-01

    Coastal erosion and shoreline retreat is of increasing concern to rural Alaskan communities, yet direct measurements remain absent over much of the coast. In southwestern Alaska, the city of Goodnews Bay has been repeatedly devastated by storms and flooding, events which forced the village to relocate to higher ground in the 1920s. Storm surges continue to damage property and infrastructure that is essential to their coastal subsistence culture. This work assesses shoreline retreat rates at the new village site based on a 58-year time series of orthorectified aerial and satellite imagery. Long-term and contemporary shoreline retreat rates are analyzed along 2.8 km of coastline fronting the village, and projected into future shoreline positions. Areas with stable shorelines are still subject to significant erosion from storm surge, which is expected to become more prevalent with shorter land-fast sea ice seasons. Sediment transport and alongshore geomorphic evolution is measured over one year using repeat beach transects with high-accuracy differential GNSS. This baseline dataset reveals locations at risk of flooding and storm surge, and serves as a benchmark for future erosion studies in the community.

  10. Abrupt Intensification of ENSO Forced By Deglacial Ice-Sheet Retreat

    NASA Astrophysics Data System (ADS)

    Lu, Z.; Liu, Z.

    2014-12-01

    The influence of ice-sheet retreat on the El Niño-Southern Oscillation (ENSO) variability is studied using a transient simulation in NCAR-CCSM3 forced only by the variations of continental ice sheets during the last deglaciation. The most striking feature is an abrupt strengthening of ENSO (by ~25%) at 14 ka BP in response to a significant retreat (an equivalent ~25 m sea-level rise) of the Laurentide ice sheet (LIS). This abrupt intensification of ENSO is caused mainly by a sudden reduction of the equatorial annual cycle through the nonlinear mechanism of frequency entrainment, rathe­­r than by the change in the large-scale tropical coupled ocean-atmosphere feedbacks (thermodynamic and mean advection dampings, the thermocline, the zonal advection and the Ekman upwelling feekbacks). The decrease of the annual cycle is a result of the reduction of the cross-equatorial SST contrast in the eastern Pacific. The more symmetric SST about the equator can be achieved predominantly by the anomalous easterly from abrupt polarward shift of jet stream in the Northern Hemisphere (NH), which propagates to tropical northeastern Pacific Ocean surface and is then reinforced by Wind-Evaporation-SST feedback. The fast sea-ice expansion in the NH induced by ice-sheet retreat could be another factor that contributes to the reduction of the cross-equatorial SST contrast and the intensification of ENSO.

  11. Debate: single-fraction treatment should be standard in the retreatment of uncomplicated bone metastases.

    PubMed

    Tsang, Derek S; Yau, Vivian; Raziee, Hamid; Niglas, Mark; Soliman, Hany; Chow, Edward; Tsao, May

    2015-10-01

    There is controversy surrounding the optimal radiotherapy dose-fractionation for retreatment of painful bone metastases. Two commonly used regimens are 8 Gy in a single-fraction or 20 Gy in five or eight fractions. Randomized evidence, including the NCIC SC.20 randomized clinical trial, has failed to standardize clinical practice. Practitioners who use single-fraction regimens cite patient convenience, fewer acute adverse effects, and better cost-effectiveness. Practitioners who prefer multiple fractions raise questions about the interpretation of data that justifies single-fraction treatment, and the possibility that single-fraction treatment may provide inferior pain relief. Given this clinical controversy, should single-fraction irradiation be standard in retreatment of uncomplicated bone metastases? In this article, two teams debate both sides of the argument with commentary to summarize the relevant issues. The conclusion from the debate is that the "standard" treatment should be individualized to the patient with shared-decision making between the oncologist, patient and family members. In a cancer patient with poor performance status and short life expectancy, single-fraction repeat radiotherapy may be preferred; in a patient with a prolonged disease course, perhaps multiple fraction retreatments would be preferred. The choice between different fractionation schemes depends on an assessment of individual patient factors, tumour factors and unique patient circumstances.

  12. Skin-deep diagnosis: affective bias and zebra retreat complicating the diagnosis of systemic sclerosis.

    PubMed

    Miller, Chad S

    2013-01-01

    Nearly half of medical errors can be attributed to an error of clinical reasoning or decision making. It is estimated that the correct diagnosis is missed or delayed in between 5% and 14% of acute hospital admissions. Through understanding why and how physicians make these errors, it is hoped that strategies can be developed to decrease the number of these errors. In the present case, a patient presented with dyspnea, gastrointestinal symptoms and weight loss; the diagnosis was initially missed when the treating physicians took mental short cuts and used heuristics as in this case. Heuristics have an inherent bias that can lead to faulty reasoning or conclusions, especially in complex or difficult cases. Affective bias, which is the overinvolvement of emotion in clinical decision making, limited the available information for diagnosis because of the hesitancy to acquire a full history and perform a complete physical examination in this patient. Zebra retreat, another type of bias, is when a rare diagnosis figures prominently on the differential diagnosis but the physician retreats for various reasons. Zebra retreat also factored in the delayed diagnosis. Through the description of these clinical reasoning errors in an actual case, it is hoped that future errors can be prevented or inspiration for additional research in this area will develop.

  13. The recent retreat of Mexican glaciers on Citlaltépetl Volcano detected using ASTER data

    NASA Astrophysics Data System (ADS)

    Cortés-Ramos, J.; Delgado-Granados, H.

    2012-08-01

    Satellite imagery and net radiation data collected between 2001 and 2007 for Citlaltépetl Volcano confirm the dramatic shrinkage of Glaciar Norte and the elimination of Jamapa and Chichimeco glacier tongues. The Glaciar Norte rapidly retreated between 2001 and 2002 while for 2007 this retreat decreases considerably. Jamapa and Chichimeco tongues disappeared by 2001 as compared to the geometry shown for 1958. The Glaciar Norte lost about 72% of its surface area between 1958 and 2007. Recently, the ice loss appears to be accelerating as evidenced by the 33% areal loss in just 6 yr between 2001 and 2007. At this shrinkage rate the glaciers would be gone from the volcano by the year 2020, which is decades earlier than previously estimated. The net radiation from ASTER images and the energy fluxes calculated via the meteorological data at the glacial surface show the close relationship between glacial shrinkage and surface energy balance. The magnitude of changes in the net radiation balance allows improved understanding of glacial retreat in Mexico.

  14. The effect of chloroform, orange oil and eucalyptol on root canal transportation in endodontic retreatment.

    PubMed

    Karataş, Ertuğrul; Kol, Elif; Bayrakdar, İbrahim Şevki; Arslan, Hakan

    2016-04-01

    The purpose of the present study was to assess the effect of solvents on root canal transportation in endodontic retreatment. Sixty extracted human permanent mandibular first molars with curved root canals were selected. All of the root canals were prepared using Twisted File Adaptive instruments (SybronEndo, Orange, CA, USA) and filled with gutta-percha and AH Plus sealer (Dentsply DeTrey, Konstanz, Germany) using the cold lateral compaction technique. The teeth were assigned to four retreatment groups as follows (n = 15): eucalyptol, chloroform, orange oil and control. The canals were scanned using cone-beam computed tomography scanning before and after instrumentation. The chloroform group showed a significantly higher mean transportation value than the orange oil and control groups at the 3 and 5 mm levels (P = 0.011 and P = 0.003, respectively). There was no significant difference among the orange oil, eucalyptol and control groups in terms of canal transportation (P > 0.61). The chloroform led to more canal transportation than the eucalyptol and orange oil during endodontic retreatment. © 2015 Australian Society of Endodontology.

  15. Prevalence of Treponema spp. in endodontic retreatment-resistant periapical lesions.

    PubMed

    Rosa, Tiago Pereira; Signoretti, Fernanda Graziela Corrêa; Montagner, Francisco; Gomes, Brenda Paula Figueiredo de Almeida; Jacinto, Rogério Castilho

    2015-01-01

    This study investigated the presence of the Treponema species in longstanding endodontic retreatment-resistant lesions of teeth with apical periodontitis, the association of this species with clinical/radiographic features, and the association among the different target species. Microbial samples of apical lesions were collected from twenty-five adult patients referred to endodontic surgery after unsuccessful root canal retreatment. Nested-PCR and conventional PCR were used for Treponema detection. Twenty-three periradicular tissue samples showed detectable levels of bacterial DNA. Treponema species were detected in 28% (7/25) of the cases. The most frequently detected species were T. socranskii (6/25), followed by T. maltophilum (3/25), T. amylovorum (3/25), T. lecithinolyticum (3/25), T. denticola (3/25), T. pectinovorum (2/25) and T. medium (2/25). T. vicentii was not detected in any sample. Positive statistical association was found between T. socranskii and T. denticola, and between T. maltophilum and T. lecithinolyticum . No association was detected between the presence of any target microorganism and the clinical or radiographic features. Treponema spp. are present, in a low percentage, in longstanding apical lesions from teeth with endodontic retreatment failure.

  16. Marine sediments in Disko Trough reveal meltwater-influenced sedimentation during ice-stream retreat

    NASA Astrophysics Data System (ADS)

    Hogan, Kelly A.; Cofaigh, Colm Ó.; Jennings, Anne E.; Dowdeswell, Julian A.

    2015-04-01

    Marine geophysical data from middle and outer Disko Trough, West Greenland reveal thick (more than ten metres) acoustically-laminated, fine-grained sediments between subglacial tills at their base and post-glacial marine sediments at the seafloor. These sediments are interpreted as a transitional facies deposited as ice retreated from the trough during deglaciation. New sediment-core records indicate that these units were likely deposited by meltwater plumes emanating from a nearby grounded-ice margin, probably during stillstands in ice retreat. The retreat of ice in the trough may have been stabilised at a narrowing in DiskoTrough on the mid-shelf, as well as at the basalt escarpment south of Disko Island. Such thicknesses of deglacial or "transitional" glacimarine sediments are relatively unusual on high-latitude continental shelves and indicate a significant meltwater production in central West Greenland during deglaciation. This is consistent with the seafloor landforms in the inner and middle parts of the trough that include channels and moats around bedrock protrusions that look to have been eroded by water. IRD counts from the cores indicate that iceberg rafting also occurred during this transitional phase but that this signal was diluted by the fine-grained transitional sediments. Once ice had withdrawn from the area and sedimentation was hemipelagic in nature the IRD signal was less diluted.

  17. Efficacy and safety of bortezomib-based retreatment at the first relapse in multiple myeloma patients: A retrospective study.

    PubMed

    Oriol, Albert; Giraldo, Pilar; Kotsianidis, Ioannis; Couturier, Catherine; Olie, Robert; Angermund, Ralf; Corso, Alessandro

    2015-08-01</