Science.gov

Sample records for interferometric images application

  1. Imaging interferometric microscopy.

    PubMed

    Schwarz, Christian J; Kuznetsova, Yuliya; Brueck, S R J

    2003-08-15

    We introduce and demonstrate a new microscopy concept: imaging interferometric microscopy (IIM), which is related to holography, synthetic-aperture imaging, and off-axis-dark-field illumination techniques. IIM is a wavelength-division multiplex approach to image formation that combines multiple images covering different spatial-frequency regions to form a composite image with a resolution much greater than that permitted by the same optical system using conventional techniques. This new type of microscopy involves both off-axis coherent illumination and reinjection of appropriate zero-order reference beams. Images demonstrate high resolution, comparable with that of a high-numerical-aperture (NA) objective, while they retain the long working distance, the large depth of field, and the large field of view of a low-NA objective. A Fourier-optics model of IIM is in good agreement with the experiment. PMID:12943079

  2. Interferometric imaging of geostationary satellites

    NASA Astrophysics Data System (ADS)

    Armstrong, J. T.; Baines, E. K.; Hindsley, R. B.; Schmitt, H. R.; Restaino, S. R.; Jorgensen, A. M.; Mozurkewich, D.

    2012-06-01

    Even the longest geosatellite, at 40 m, subtends only 0.2 arcsec (1 microradian). Determining structure and orientation with 10 cm resolution requires a 90 m telescope at visual wavelengths, or an interferometer. We de- scribe the application of optical interferometry to observations of complex extended targets such as geosatellites, and discuss some of its challenges. We brie y describe our Navy Optical Interferometer (NOI) group's eorts toward interferometric observations of geosatellites, including the rst interferometric detection of a geosatellite. The NOI observes in 16 spectral channels (550{850 nm) using up to six 12-cm apertures, with baselines (separa- tions between apertures) of 16 to 79 m. We detected the geosatellite DirecTV-9S during glint seasons in March 2008 and March 2009, using a single 16 m baseline (resolution 1:6 m). Fringes on a longer baseline were too weak because the large-scale structure was over-resolved. The fringe strengths are consistent with a combination of two size scales, 1:3 m and & 3:5 m. Our near term NOI work is directed toward observing geosatellites with three or more 10 to 15 m baselines, using closure phase measurements to remove atmospheric turbulence eects and coherent data averaging to increase the SNR. Beyond the two- to three-year time frame, we plan to install larger apertures (1.4 and 1.8 m), allowing observations outside glint season, and to develop baseline bootstrap- ping, building long baselines from chains of short baselines, to avoid over-resolution while increasing maximum resolution. Our ultimate goal is to develop the design parameters for dedicated satellite imaging interferometry.

  3. Registration of interferometric SAR images

    NASA Technical Reports Server (NTRS)

    Lin, Qian; Vesecky, John F.; Zebker, Howard A.

    1992-01-01

    Interferometric synthetic aperture radar (INSAR) is a new way of performing topography mapping. Among the factors critical to mapping accuracy is the registration of the complex SAR images from repeated orbits. A new algorithm for registering interferometric SAR images is presented. A new figure of merit, the average fluctuation function of the phase difference image, is proposed to evaluate the fringe pattern quality. The process of adjusting the registration parameters according to the fringe pattern quality is optimized through a downhill simplex minimization algorithm. The results of applying the proposed algorithm to register two pairs of Seasat SAR images with a short baseline (75 m) and a long baseline (500 m) are shown. It is found that the average fluctuation function is a very stable measure of fringe pattern quality allowing very accurate registration.

  4. Analysis of an interferometric Stokes imaging polarimeter

    NASA Astrophysics Data System (ADS)

    Murali, Sukumar

    Estimation of Stokes vector components from an interferometric fringe encoded image is a novel way of measuring the State Of Polarization (SOP) distribution across a scene. Imaging polarimeters employing interferometric techniques encode SOP in- formation across a scene in a single image in the form of intensity fringes. The lack of moving parts and use of a single image eliminates the problems of conventional polarimetry - vibration, spurious signal generation due to artifacts, beam wander, and need for registration routines. However, interferometric polarimeters are limited by narrow bandpass and short exposure time operations which decrease the Signal to Noise Ratio (SNR) defined as the ratio of the mean photon count to the standard deviation in the detected image. A simulation environment for designing an Interferometric Stokes Imaging polarimeter (ISIP) and a detector with noise effects is created and presented. Users of this environment are capable of imaging an object with defined SOP through an ISIP onto a detector producing a digitized image output. The simulation also includes bandpass imaging capabilities, control of detector noise, and object brightness levels. The Stokes images are estimated from a fringe encoded image of a scene by means of a reconstructor algorithm. A spatial domain methodology involving the idea of a unit cell and slide approach is applied to the reconstructor model developed using Mueller calculus. The validation of this methodology and effectiveness compared to a discrete approach is demonstrated with suitable examples. The pixel size required to sample the fringes and minimum unit cell size required for reconstruction are investigated using condition numbers. The importance of the PSF of fore-optics (telescope) used in imaging the object is investigated and analyzed using a point source imaging example and a Nyquist criteria is presented. Reconstruction of fringe modulated images in the presence of noise involves choosing an

  5. Transient volcano deformation sources imaged with interferometric synthetic aperture radar: Application to Seguam Island, Alaska

    USGS Publications Warehouse

    Masterlark, Timothy; Lu, Zhong

    2004-01-01

    Thirty interferometric synthetic aperture radar (InSAR) images, spanning various intervals during 1992–2000, document coeruptive and posteruptive deformation of the 1992–1993 eruption on Seguam Island, Alaska. A procedure that combines standard damped least squares inverse methods and collective surfaces, identifies three dominant amorphous clusters of deformation point sources. Predictions generated from these three point source clusters account for both the spatial and temporal complexity of the deformation patterns of the InSAR data. Regularized time series of source strength attribute a distinctive transient behavior to each of the three source clusters. A model that combines magma influx, thermoelastic relaxation, poroelastic effects, and petrologic data accounts for the transient, interrelated behavior of the source clusters and the observed deformation. Basaltic magma pulses, which flow into a storage chamber residing in the lower crust, drive this deformational system. A portion of a magma pulse is injected into the upper crust and remains in storage during both coeruption and posteruption intervals. This injected magma degasses and the volatile products accumulate in a shallow poroelastic storage chamber. During the eruption, another portion of the magma pulse is transported directly to the surface via a conduit roughly centered beneath Pyre Peak on the west side of the island. A small amount of this magma remains in storage during the eruption, and posteruption thermoelastic contraction ensues. This model, made possible by the excellent spatial and temporal coverage of the InSAR data, reveals a relatively simple system of interrelated predictable processes driven by magma dynamics.

  6. The 2014 interferometric imaging beauty contest

    NASA Astrophysics Data System (ADS)

    Monnier, John D.; Berger, Jean-Philippe; Le Bouquin, Jean-Baptiste; Tuthill, Peter G.; Wittkowski, Markus; Grellmann, Rebekka; Müller, André; Renganswany, Sridhar; Hummel, Christian; Hofmann, Karl-Heinz; Schertl, Dieter; Weigelt, Gerd; Young, John; Buscher, David; Sanchez-Bermudez, Joel; Alberdi, Antxon; Schoedel, Rainer; Köhler, Rainer; Soulez, Ferréol; Thiébaut, Éric; Kluska, Jacques; Malbet, Fabien; Duvert, Gilles; Kraus, Stefan; Kloppenborg, Brian K.; Baron, Fabien; de Wit, Willem-Jan; Rivinius, Thomas; Merand, Antoine

    2014-07-01

    Here we present the results of the 6th biennial optical interferometry imaging beauty contest. Taking advantage of a unique opportunity, the red supergiant VY CMa and the Mira variable R Car were observed in the astronomical H-band with three 4-telescope configurations of the VLTI-AT array using the PIONIER instrument. The community was invited to participate in the subsequent image reconstruction and interpretation phases of the project. Ten groups submitted entries to the beauty contest, and we found reasonable consistency between images obtained from independent workers using quite different algorithms. We also found that significant differences existed between the submitted images, much greater than in past beauty contests that were all based on simulated data. A novel crowd-sourcing" method allowed consensus median images to be constructed, filtering likely artifacts and retaining real features." We definitively detect strong spots on the surfaces of both stars as well as distinct circumstellar shells of emission (likely water/CO) around R Car. In a close contest, Joel Sanchez (IAA-CSIC/Spain) was named the winner of the 2014 interferometric imaging beauty contest. This process has shown that new comers" can use publicly-available imaging software to interpret VLTI/PIONIER imaging data, as long as sufficient observations are taken to have complete uv coverage { a luxury that is often missing. We urge proposers to request adequate observing nights to collect sufficient data for imaging and for time allocation committees to recognise the importance of uv coverage for reliable interpretation of interferometric data. We believe that the result of the proposed broad international project will contribute to inspiring trust in the image reconstruction processes in optical interferometry.

  7. Molecular histopathology by nonlinear interferometric vibrational imaging

    NASA Astrophysics Data System (ADS)

    Boppart, Stephen A.

    2011-07-01

    A rapid label-free approach for molecular histopathology is presented and reviewed. Broadband vibrational spectra are generated by nonlinear interferometric vibrational imaging (NIVI), a coherent anti-Stokes Raman scattering (CARS)- based technique that uses interferometry and signal processing approaches to acquire Raman-like profiles with suppression of the non-resonant background. This allows for the generation of images that provide contrast based on quantitative chemical composition with high spatial and spectral resolution. Algorithms are demonstrated for reducing the diagnostic spectral information into color-coded composite images for the rapid identification of chemical constituents in skin, as well as differentiating normal from abnormal tissue in a pre-clinical tumor model for human breast cancer. This technology and methodology could result in an alternative method to the traditional histological staining and subjective interpretation procedure currently used in the diagnosis of disease, and has the potential for future in vivo molecular histopathology.

  8. Using APES for interferometric SAR imaging.

    PubMed

    Palsetia, M R; Li, J

    1998-01-01

    We present an adaptive finite impulse response (FIR) filtering approach, which is referred to as the Amplitude and Phase EStimation (APES) algorithm, for interferometric synthetic aperture radar (SAR) imaging. We compare the APES algorithm with other FIR filtering approaches including the Capon and fast Fourier transform (FFT) methods. We show via both numerical and experimental examples that the adaptive FIR filtering approaches such as Capon and APES can yield more accurate spectral estimates with much lower sidelobes and narrower spectral peaks than the FFT method. We show that although the APES algorithm yields somewhat wider spectral peaks than the Capon method, the former gives more accurate overall spectral estimates and SAR images than the latter and the FFT method.

  9. Wideband Interferometric Sensing and Imaging Polarimetry

    NASA Technical Reports Server (NTRS)

    Verdi, James Salvatore; Kessler, Otto; Boerner, Wolfgang-Martin

    1996-01-01

    Wideband Interferometric Sensing and Imaging Polarimetry (WISIP) has become an important, indispensible tool in wide area military surveillance and global environmental monitoring of the terrestrial and planetary covers. It enables dynamic, real time optimal feature extraction of significant characteristics of desirable targets and/or target sections with simultaneous suppression of undesirable background clutter and propagation path speckle at hitherto unknown clarity and never before achieved quality. WISIP may be adopted to the detection, recognition, and identification (DRI) of any stationary, moving or vibrating targets or distributed scatterer segments versus arbitrary stationary, dynamical changing and/or moving geo-physical/ecological environments, provided the instantaneous 2x2 phasor and 4x4 power density matrices for forward propagation/backward scattering, respectively, can be measured with sufficient accuracy. For example, the DRI of stealthy, dynamically moving inhomogeneous volumetric scatter environments such as precipitation scatter, the ocean/sea/lake surface boundary layers, the littoral coastal surf zones, pack ice and snow or vegetative canopies, dry sands and soils, etc. can now be successfully realized. A comprehensive overview is presented on how these modern high resolution/precision, complete polarimetric co-registered signature sensing and imaging techniques, complemented by full integration of novel navigational electronic tools, such as DGPS, will advance electromagnetic vector wave sensing and imaging towards the limits of physical realization. Various examples utilizing the most recent image data take sets of airborne, space shuttle, and satellite imaging systems demonstrate the utility of WISIP.

  10. Applications of a non-interferometric x-ray phase contrast imaging method with both synchrotron and conventional sources

    NASA Astrophysics Data System (ADS)

    Endrizzi, M.; Diemoz, P. C.; Munro, P. R. T.; Hagen, C. K.; Szafraniec, M. B.; Millard, T. P.; Zapata, C. E.; Speller, R. D.; Olivo, A.

    2013-05-01

    We have developed a totally incoherent, non-interferometric x-ray phase contrast imaging (XPCI) method. This is based on the edge illumination (EI) concept developed at the ELETTRA synchrotron in Italy in the late `90s. The method was subsequently adapted to the divergent beam generated by a conventional source, by replicating it for every detector line through suitable masks. The method was modelled both with the simplified ray-tracing and with the more rigorous wave-optics approach, and in both cases excellent agreement with the experimental results was found. The wave-optics model enabled assessing the methods' coherence requirements, showing that they are at least an order of magnitude more relaxed than in other methods, without this having negative consequences on the phase sensitivity. Our masks have large pitches (up to 50 times larger than in grating interferometry, for example), which allows for manufacturing through standard lithography, scalability, cost-effectiveness and easiness to align. When applied to a polychromatic and divergent beam generated by a conventional source, the method enables the detection of strong phase effects also with uncollimated, unapertured sources with focal spots of up to 100 μm, compatible with the state-of-the-art in mammography. When used at synchrotrons, it enables a contrast increase of orders of magnitude over other methods. Robust phase retrieval was proven for both coherent and incoherent sources, and additional advantages are compatibility with high x-ray energies and easy implementation of phase sensitivity in two directions simultaneously. This paper briefly summarizes these achievements and reviews some of the key results.

  11. Relative elastic interferometric imaging for microseismic source location

    NASA Astrophysics Data System (ADS)

    Li, Lei; Chen, Hao; Wang, Xiuming

    2016-10-01

    Combining a relative location method and seismic interferometric imaging, a relative elastic interferometric imaging method for microseismic source location is proposed. In the method, the information of a known event (the main event) is fully used to improve the location precision of the unknown events (the target events). First, the principles of both conventional and the relative interferometric imaging methods are analyzed. Traveltime differences from the position of the same potential event to different receivers are used in direct interferometric imaging, while relative interferometric imaging utilizes those of different events to the same receiver. Second, 2D and 3D numerical experiments demonstrate the feasibility of this newly proposed method in locating a single microseismic event. Envelopes of cross-correlation traces are utilized to eliminate the effects of changing polarities resulting from the source mechanism and receiver configuration. Finally, the location precision of the relative and conventional interferometric imaging methods are compared, and it indicates that the former hold both advantages of the relative method and interferometric imaging. Namely, it can adapt to comparatively high velocity error and low signal-to-noise ratio (SNR) microseismic data. Moreover, since there is no arrival time picking and fewer cross-correlograms are imaged, the method also significantly saves computational expense.

  12. A novel lightweight Fizeau infrared interferometric imaging system

    NASA Astrophysics Data System (ADS)

    Hope, Douglas A.; Hart, Michael; Warner, Steve; Durney, Oli; Romeo, Robert

    2016-05-01

    Aperture synthesis imaging techniques using an interferometer provide a means to achieve imagery with spatial resolution equivalent to a conventional filled aperture telescope at a significantly reduced size, weight and cost, an important implication for air- and space-borne persistent observing platforms. These concepts have been realized in SIRII (Space-based IR-imaging interferometer), a new light-weight, compact SWIR and MWIR imaging interferometer designed for space-based surveillance. The sensor design is configured as a six-element Fizeau interferometer; it is scalable, light-weight, and uses structural components and main optics made of carbon fiber replicated polymer (CFRP) that are easy to fabricate and inexpensive. A three-element prototype of the SIRII imager has been constructed. The optics, detectors, and interferometric signal processing principles draw on experience developed in ground-based astronomical applications designed to yield the highest sensitivity and resolution with cost-effective optical solutions. SIRII is being designed for technical intelligence from geo-stationary orbit. It has an instantaneous 6 x 6 mrad FOV and the ability to rapidly scan a 6x6 deg FOV, with a minimal SNR. The interferometric design can be scaled to larger equivalent filled aperture, while minimizing weight and costs when compared to a filled aperture telescope with equivalent resolution. This scalability in SIRII allows it address a range of IR-imaging scenarios.

  13. Using APES for interferometric SAR imaging

    NASA Astrophysics Data System (ADS)

    Li, Jian; Palsetia, Marzban

    1996-06-01

    In this paper, we present an adaptive FIR filtering approach, which is referred to as the APES (amplitude and phase estimation of a sinusoid) algorithm, for interferometric SAR imaging. We apply the APES algorithm on the data obtained from two vertically displaced apertures of a SAR system to obtain the complex amplitude and the phase difference estimates, which are proportional to the radar cross section and the height of the scatterer, respectively, at the frequencies of interest. We also demonstrate how the APES algorithm can be applied to data matrices with large dimensions without incurring high computational overheads. We compare the APES algorithm with other FIR filtering approaches including the Capon and FFT methods. We show via both numerical and experimental examples that the adaptive FIR filtering approaches such as Capon and APES can yield more accurate spectral estimates with much lower sidelobes and narrower spectral peaks than the FFT method. We show that although the APES algorithm yields somewhat wider spectral peaks than the Capon method, the former gives more accurate overall spectral estimates and SAR images than the latter and the FFT method.

  14. Interferometric radar imaging using the AN/APG-76 radar

    NASA Astrophysics Data System (ADS)

    O'Brien, James D.; Holt, Hugh D., Jr.; Maney, Harold D., Jr.; Orwig, Lawrence P.

    1996-06-01

    This paper describes recent performance-enhancing modifications made to the AN/APG-76 radar. An interferometric radar equipped with a four-channel receiver and a seven-channel interferometric antenna, the AN/APG-76 has been used to demonstrate novel interferometric imaging concepts. Originally built as a tactical radar with air-to- air modes, SAR, and three-channel DPCA-like MTI modes, the modified radar's capabilities include: real-time autofocused imaging at 3- and 1-foot resolutions, elevation interferometric SAR (both single and repeat pass), polarimetric imaging, precision tracking by means of a tightly-coupled GPS-aided INS system, and moving target imaging using the inherent clutter-cancellation capabilities of the radar. The re-programmability of the on-board processor allows new real-time modes to be implemented, and high-speed data recording allows off-line analysis of data.

  15. Interferometric SAR imaging by transmitting stepped frequency chaotic noise signals

    NASA Astrophysics Data System (ADS)

    Zhang, Yunhua; Gu, Xiang; Zhai, Wenshuai; Dong, Xiao; Shi, Xiaojin; Kang, Xueyan

    2015-10-01

    Noise radar has been applied in many fields since it was proposed more than 50 years ago. However, it has not been applied to interferometric SAR imaging yet as far as we know. This paper introduces our recent work on interferometric noise radar. An interferometric SAR system was developed which can transmit both chirp signal and chaotic noise signal (CNS) at multiple carrier frequencies. An airborne experiment with this system by transmitting both signals was carried out, and the data were processed to show the capability of interferometric SAR imaging with CNS. The results shows that although the interferometric phase quality of CNS is degraded due to the signal to noise ratio (SNR) is lower compared with that of chirp signal, we still can get satisfied DEM after multi-looking processing. Another work of this paper is to apply compressed sensing (CS) theory to the interferometric SAR imaging with CNS. The CS theory states that if a signal is sparse, then it can be accurately reconstructed with much less sampled data than that regularly required according to Nyquist Sampling Theory. To form a structured random matrix, if the transmitted signal is of fixed waveform, then random subsampling is needed. However, if the transmitted signal is of random waveform, then only uniform subsampling is needed. This is another advantage of noise signal. Both the interferometric phase images and the DEMs by regular method and by CS method are processed with results compared. It is shown that the degradation of interferometric phases due to subsampling is larger than that of amplitude image.

  16. Terahertz interferometric synthetic aperture tomography for confocal imaging systems.

    PubMed

    Heimbeck, M S; Marks, D L; Brady, D; Everitt, H O

    2012-04-15

    Terahertz (THz) interferometric synthetic aperture tomography (TISAT) for confocal imaging within extended objects is demonstrated by combining attributes of synthetic aperture radar and optical coherence tomography. Algorithms recently devised for interferometric synthetic aperture microscopy are adapted to account for the diffraction-and defocusing-induced spatially varying THz beam width characteristic of narrow depth of focus, high-resolution confocal imaging. A frequency-swept two-dimensional TISAT confocal imaging instrument rapidly achieves in-focus, diffraction-limited resolution over a depth 12 times larger than the instrument's depth of focus in a manner that may be easily extended to three dimensions and greater depths.

  17. New Theoretical Frameworks for Interferometric Imaging

    NASA Astrophysics Data System (ADS)

    Baron, F.; Monnier, J.; Young, J.; Buscher, D.

    2014-09-01

    With the advent of new instruments (MIRC-6T at CHARA, PIONEER at VLTI, and VISION at NPOI) as well as the construction of MROI, the focus in optical and infrared interferometry has shifted toward imaging. However, examining the current “model-independent” image reconstruction packages proves they are often inadequate to reconstruct even simple objects. We present here two possible paths that are being explored to improve the quality of image reconstruction. The first is the Compressed Sensing framework, which prescribes the use of spatial bases in which the object is sparse. The second is the Bayesian evidence framework, which allows to discrimination between physical models in imaging. We illustrate the application of both frameworks with reconstruction of a simulated spotted star.

  18. Interferometric SAR to EO image registration problem

    NASA Astrophysics Data System (ADS)

    Rogers, George W.; Mansfield, Arthur W.; Rais, Houra

    2000-08-01

    Historically, SAR to EO registration accuracy has been at the multiple pixel level compared to sub-pixel EO to EO registration accuracies. This is due to a variety of factors including the different scattering characteristics of the ground for EO and SAR, SAR speckle, and terrain induced geometric distortion. One approach to improving the SAR to EO registration accuracy is to utilize the full information from multiple SAR surveys using interferometric techniques. In this paper we will examine this problem in detail with an example using ERS SAR imagery. Estimates of the resulting accuracy based on ERS are included.

  19. PP and PS interferometric images of near-seafloor sediments

    USGS Publications Warehouse

    Haines, S.S.

    2011-01-01

    I present interferometric processing examples from an ocean-bottom cable OBC dataset collected at a water depth of 800 m in the Gulf of Mexico. Virtual source and receiver gathers created through cross-correlation of full wavefields show clear PP reflections and PS conversions from near-seafloor layers of interest. Virtual gathers from wavefield-separated data show improved PP and PS arrivals. PP and PS brute stacks from the wavefield-separated data compare favorably with images from a non-interferometric processing flow. ?? 2011 Society of Exploration Geophysicists.

  20. Code-modulated interferometric imaging system using phased arrays

    NASA Astrophysics Data System (ADS)

    Chauhan, Vikas; Greene, Kevin; Floyd, Brian

    2016-05-01

    Millimeter-wave (mm-wave) imaging provides compelling capabilities for security screening, navigation, and bio- medical applications. Traditional scanned or focal-plane mm-wave imagers are bulky and costly. In contrast, phased-array hardware developed for mass-market wireless communications and automotive radar promise to be extremely low cost. In this work, we present techniques which can allow low-cost phased-array receivers to be reconfigured or re-purposed as interferometric imagers, removing the need for custom hardware and thereby reducing cost. Since traditional phased arrays power combine incoming signals prior to digitization, orthogonal code-modulation is applied to each incoming signal using phase shifters within each front-end and two-bit codes. These code-modulated signals can then be combined and processed coherently through a shared hardware path. Once digitized, visibility functions can be recovered through squaring and code-demultiplexing operations. Pro- vided that codes are selected such that the product of two orthogonal codes is a third unique and orthogonal code, it is possible to demultiplex complex visibility functions directly. As such, the proposed system modulates incoming signals but demodulates desired correlations. In this work, we present the operation of the system, a validation of its operation using behavioral models of a traditional phased array, and a benchmarking of the code-modulated interferometer against traditional interferometer and focal-plane arrays.

  1. Interferometric Imaging of Molecular Envelopes with and without YSOs<

    NASA Astrophysics Data System (ADS)

    Ohashi, Nagayoshi

    1999-10-01

    Molecular envelopes are sites of star formation, and their geometrical and kinematical properties are very important to understand star formation. Particularly, their velocity structures, such as infall or rotation, need to be studied in detail to understand processes essential for star-formation. In order to investigate the physical properties of molecular envelopes in very detail, we need fine angular and velocity resolutions, which resolve both geometrical and velocity structures of molecular envelopes. A millimeter & submillimeter-wave interferometer is a very powerful tool providing high angular and velocity resolutions. Interferometric observations have realized direct imaging of infalling motions in molecular envelopes. In my talk, I will review what we learned about the physical properties of molecular envelopes with and without young stellar objects (YSOs) through interferometric observations. I will also discuss what we may learn about star-formation using a large millimeter & submillimeter array.

  2. Two microstrip arrays for interferometric SAR applications

    NASA Technical Reports Server (NTRS)

    Huang, J.

    1993-01-01

    Two types of C-band aircraft interferometric Synthetic Aperture Radar (SAR) are being developed at JPL to measure the ocean wave characteristics. Each type requires two identical antennas with each having a long rectangular aperture to radiate fan-shaped beam(s). One type of these radars requires each of its antennas to radiate a broadside beam that will measure the target's cross-track velocity. The other type, having each of its antennas to radiate two off-broadside pointed beams, will allow the measurement of both the cross-track and the along-track velocities of the target. Because flush mounting of the antenna on the aircraft fuselage is desirable, microstrip patch array is selected for these interferometric SAR antennas. To meet the radar system requirement, each array needs a total of 76 microstrip patches which are arranged in a 38 x 2 rectangular aperture with a physical size of 1.6m x 16.5cm. To minimize the insertion loss and physical real estate of this relatively long array, a combined series/parallel feed technique is used. Techniques to suppress cross-pol radiation and to effectively utilize the RF power are also implemented. Cross-pol level of lower than -30 dB from the co-pol peak and low insertion loss of 0.36 dB have been achieved for both types of arrays. For the type of radar that requires two off-braodside pointed beams, a simple phasing technique is used to achieve this dual-beam capability with adequate antenna gain (20 dBi) and sidelobe level (-14 dB). Both radar arrays have been flight tested on aircraft with excellent antenna performance demonstrated.

  3. Interferometric system for precision imaging of vibrating structures

    NASA Technical Reports Server (NTRS)

    Gutierrez, Roman C. (Inventor); Shcheglov, Kirill V. (Inventor); Tang, Tony (Inventor)

    2001-01-01

    An optical profiler is modified in a way which allows it to image a MEMS device at various points during the movement of the MEMS device. The light source is synchronized with a desired movement of the MEMS device. The light source produces pulse at each synchronization period. During each pulse, an interferometric measurement is carried out. So long as the pulse is short enough such that the device does not move significantly, a detection of the position of the device can be accurately obtained.

  4. Biomolecular detection employing the Interferometric Reflectance Imaging Sensor (IRIS).

    PubMed

    Lopez, Carlos A; Daaboul, George G; Ahn, Sunmin; Reddington, Alexander P; Monroe, Margo R; Zhang, Xirui; Irani, Rostem J; Yu, Chunxiao; Genco, Caroline A; Cretich, Marina; Chiari, Marcella; Goldberg, Bennett B; Connor, John H; Ünlü, M Selim

    2011-05-03

    The sensitive measurement of biomolecular interactions has use in many fields and industries such as basic biology and microbiology, environmental/agricultural/biodefense monitoring, nanobiotechnology, and more. For diagnostic applications, monitoring (detecting) the presence, absence, or abnormal expression of targeted proteomic or genomic biomarkers found in patient samples can be used to determine treatment approaches or therapy efficacy. In the research arena, information on molecular affinities and specificities are useful for fully characterizing the systems under investigation. Many of the current systems employed to determine molecular concentrations or affinities rely on the use of labels. Examples of these systems include immunoassays such as the enzyme-linked immunosorbent assay (ELISA), polymerase chain reaction (PCR) techniques, gel electrophoresis assays, and mass spectrometry (MS). Generally, these labels are fluorescent, radiological, or colorimetric in nature and are directly or indirectly attached to the molecular target of interest. Though the use of labels is widely accepted and has some benefits, there are drawbacks which are stimulating the development of new label-free methods for measuring these interactions. These drawbacks include practical facets such as increased assay cost, reagent lifespan and usability, storage and safety concerns, wasted time and effort in labelling, and variability among the different reagents due to the labelling processes or labels themselves. On a scientific research basis, the use of these labels can also introduce difficulties such as concerns with effects on protein functionality/structure due to the presence of the attached labels and the inability to directly measure the interactions in real time. Presented here is the use of a new label-free optical biosensor that is amenable to microarray studies, termed the Interferometric Reflectance Imaging Sensor (IRIS), for detecting proteins, DNA, antigenic material

  5. Interferometric and nonlinear-optical spectral-imaging techniques for outer space and live cells

    NASA Astrophysics Data System (ADS)

    Itoh, Kazuyoshi

    2015-12-01

    Multidimensional signals such as the spectral images allow us to have deeper insights into the natures of objects. In this paper the spectral imaging techniques that are based on optical interferometry and nonlinear optics are presented. The interferometric imaging technique is based on the unified theory of Van Cittert-Zernike and Wiener-Khintchine theorems and allows us to retrieve a spectral image of an object in the far zone from the 3D spatial coherence function. The retrieval principle is explained using a very simple object. The promising applications to space interferometers for astronomy that are currently in progress will also be briefly touched on. An interesting extension of interferometric spectral imaging is a 3D and spectral imaging technique that records 4D information of objects where the 3D and spectral information is retrieved from the cross-spectral density function of optical field. The 3D imaging is realized via the numerical inverse propagation of the cross-spectral density. A few techniques suggested recently are introduced. The nonlinear optical technique that utilizes stimulated Raman scattering (SRS) for spectral imaging of biomedical targets is presented lastly. The strong signals of SRS permit us to get vibrational information of molecules in the live cell or tissue in real time. The vibrational information of unstained or unlabeled molecules is crucial especially for medical applications. The 3D information due to the optical nonlinearity is also the attractive feature of SRS spectral microscopy.

  6. Interferometric out-of-focus imaging of ice particles with overlapping images.

    PubMed

    Brunel, M; Lemaitre, P; Porcheron, E; Coëtmellec, S; Gréhan, G; Jacquot-Kielar, J

    2016-06-20

    It is shown that the size and relative positions of two irregular rough particles can be analyzed using interferometric out-of-focus imaging despite the overlapping of their out-of-focus images. Simulations are confirmed by experiments done with ice particles generated in a freezing column. PMID:27409116

  7. Polarization interferometric nulling coronagraph for high-contrast imaging.

    PubMed

    Murakami, Naoshi; Yokochi, Kaito; Nishikawa, Jun; Tamura, Motohide; Kurokawa, Takashi; Takeda, Mitsuo; Baba, Naoshi

    2010-06-01

    We propose a novel, high-contrast imager called a polarization interferometric nulling coronagraph (PINC) for direct detection of extrasolar planets. The PINC uses achromatic half-wave plates (HWPs) installed in a fully symmetric beam combiner based on polarizing beam splitters. Jones calculus suggests that a stellar halo suppression level of 10(-10) can be achieved at 5 lambda/D for a broad wavelength range from 1.6 to 2.2 microm by using Fresnel-rhomb HWPs made of BK7. Laboratory experiments on the PINC used two laser light sources (wavelengths of lambda=532 and 671 nm), and we obtained a halo suppression level of approximately 10(-6) at 5 lambda/D for both wavelengths. PMID:20517351

  8. Hyperspectral imaging with in-line interferometric femtosecond stimulated Raman scattering spectroscopy

    NASA Astrophysics Data System (ADS)

    Dobner, Sven; Fallnich, Carsten

    2014-02-01

    We present the hyperspectral imaging capabilities of in-line interferometric femtosecond stimulated Raman scattering. The beneficial features of this method, namely, the improved signal-to-background ratio compared to other applicable broadband stimulated Raman scattering methods and the simple experimental implementation, allow for a rather fast acquisition of three-dimensional raster-scanned hyperspectral data-sets, which is shown for PMMA beads and a lipid droplet in water as a demonstration. A subsequent application of a principle component analysis displays the chemical selectivity of the method.

  9. Hyperspectral imaging with in-line interferometric femtosecond stimulated Raman scattering spectroscopy.

    PubMed

    Dobner, Sven; Fallnich, Carsten

    2014-02-28

    We present the hyperspectral imaging capabilities of in-line interferometric femtosecond stimulated Raman scattering. The beneficial features of this method, namely, the improved signal-to-background ratio compared to other applicable broadband stimulated Raman scattering methods and the simple experimental implementation, allow for a rather fast acquisition of three-dimensional raster-scanned hyperspectral data-sets, which is shown for PMMA beads and a lipid droplet in water as a demonstration. A subsequent application of a principle component analysis displays the chemical selectivity of the method.

  10. MODELING VERY LONG BASELINE INTERFEROMETRIC IMAGES WITH THE CROSS-ENTROPY GLOBAL OPTIMIZATION TECHNIQUE

    SciTech Connect

    Caproni, A.; Toffoli, R. T.; Monteiro, H.; Abraham, Z.; Teixeira, D. M.

    2011-07-20

    We present a new technique for obtaining model fittings to very long baseline interferometric images of astrophysical jets. The method minimizes a performance function proportional to the sum of the squared difference between the model and observed images. The model image is constructed by summing N{sub s} elliptical Gaussian sources characterized by six parameters: two-dimensional peak position, peak intensity, eccentricity, amplitude, and orientation angle of the major axis. We present results for the fitting of two main benchmark jets: the first constructed from three individual Gaussian sources, the second formed by five Gaussian sources. Both jets were analyzed by our cross-entropy technique in finite and infinite signal-to-noise regimes, the background noise chosen to mimic that found in interferometric radio maps. Those images were constructed to simulate most of the conditions encountered in interferometric images of active galactic nuclei. We show that the cross-entropy technique is capable of recovering the parameters of the sources with a similar accuracy to that obtained from the very traditional Astronomical Image Processing System Package task IMFIT when the image is relatively simple (e.g., few components). For more complex interferometric maps, our method displays superior performance in recovering the parameters of the jet components. Our methodology is also able to show quantitatively the number of individual components present in an image. An additional application of the cross-entropy technique to a real image of a BL Lac object is shown and discussed. Our results indicate that our cross-entropy model-fitting technique must be used in situations involving the analysis of complex emission regions having more than three sources, even though it is substantially slower than current model-fitting tasks (at least 10,000 times slower for a single processor, depending on the number of sources to be optimized). As in the case of any model fitting

  11. Sparse representations and convex optimization as tools for LOFAR radio interferometric imaging

    NASA Astrophysics Data System (ADS)

    Girard, J. N.; Garsden, H.; Starck, J. L.; Corbel, S.; Woiselle, A.; Tasse, C.; McKean, J. P.; Bobin, J.

    2015-08-01

    Compressed sensing theory is slowly making its way to solve more and more astronomical inverse problems. We address here the application of sparse representations, convex optimization and proximal theory to radio interferometric imaging. First, we expose the theory behind interferometric imaging, sparse representations and convex optimization, and second, we illustrate their application with numerical tests with SASIR, an implementation of the FISTA, a Forward-Backward splitting algorithm hosted in a LOFAR imager. Various tests have been conducted in Garsden et al., 2015. The main results are: i) an improved angular resolution (super resolution of a factor ≈ 2) with point sources as compared to CLEAN on the same data, ii) correct photometry measurements on a field of point sources at high dynamic range and iii) the imaging of extended sources with improved fidelity. SASIR provides better reconstructions (five time less residuals) of the extended emission as compared to CLEAN. With the advent of large radiotelescopes, there is scope for improving classical imaging methods with convex optimization methods combined with sparse representations.

  12. FURTHER EVALUATION OF BOOTSTRAP RESAMPLING AS A TOOL FOR RADIO-INTERFEROMETRIC IMAGING FIDELITY ASSESSMENT

    SciTech Connect

    Kemball, Athol; Mitra, Modhurita; Chiang, H.-F.

    2010-01-15

    We report on a broader evaluation of statistical bootstrap resampling methods as a tool for pixel-level calibration and imaging fidelity assessment in radio interferometry. Pixel-level imaging fidelity assessment is a challenging problem, important for the value it holds in robust scientific interpretation of interferometric images, enhancement of automated pipeline reduction systems needed to broaden the user community for these instruments, and understanding leading-edge direction-dependent calibration and imaging challenges for future telescopes such as the Square Kilometre Array. This new computational approach is now possible because of advances in statistical resampling for data with long-range dependence and the available performance of contemporary high-performance computing resources. We expand our earlier numerical evaluation to span a broader domain subset in simulated image fidelity and source brightness distribution morphologies. As before, we evaluate the statistical performance of the bootstrap resampling methods against direct Monte Carlo simulation. We find that both model-based and subsample bootstrap methods continue to show significant promise for the challenging problem of interferometric imaging fidelity assessment when evaluated over the broader domain subset. We report on their measured statistical performance and guidelines for their use and application in practice. We also examine the performance of the underlying polarization self-calibration algorithm used in this study over a range of parallactic angle coverage.

  13. Size determination of mixed liquid and frozen water droplets using interferometric out-of-focus imaging

    NASA Astrophysics Data System (ADS)

    Jacquot Kielar, Justin; Wu, Yingchun; Coëtmellec, Sébastien; Lebrun, Denis; Gréhan, Gérard; Brunel, Marc

    2016-07-01

    We record simultaneously interferometric out-of-focus images and digital in-line holograms of liquid and frozen water droplets. We show that the analysis of speckle-like out-of-focus images allows a quantitative estimation of the size of the particles which is corroborated by numerical reconstruction of holograms recorded simultaneously. Interferometric out-of-focus imaging could be extended to the characterization of ice in clouds in the atmosphere.

  14. Interferometric techniques in seismic reflection imaging and the principle of stationary phase

    NASA Astrophysics Data System (ADS)

    Snieder, R.

    2005-05-01

    Interferometric imaging where the Green's function is constructed using the correlation of complex wavefields recorded at two receivers is a rapidly emerging field. The methodology has been justified based on assumptions of equiparitioning of the normal modes of the system, as well as on various versions of the representation theorem applied to time-reversed waves. I will present another point of view that is based on stationary phase arguments. This complementary formulation of interferometric imaging gives insight in the physics of the emergence of the Green's function, and of the limitations that are encountered when applying this technique to data. Issues that will be covered are the relation between ensemble averaging and time averaging, and interferometric imaging of reflected waves. This example is of particular interest for exploration seisology since it shows that interferometric imaging may introduce spurious multiple reflections. I will show that these "multiples" have a clear physical interpretation and do not form a problem in seismic imaging.

  15. Blind estimation of interferometric SAR phase images through fuzzy matching-pursuits

    NASA Astrophysics Data System (ADS)

    Aiazzi, Bruno; Alparone, Luciano; Baronti, Stefano; Bianchini, Massimo

    2002-01-01

    This paper presents an original application of fuzzy logic to restoration of interferometric phase images from IFSAR, which are affected by zero-mean uncorrelated noise, whose variance depends on the underlying coherence, thus resulting in a nonstationary random process. Spatial filtering of the phase noise is recommended, either before phase unwrapping is accomplished, or simultaneously with it. In fact, phase unwrapping basically relies on a smoothness constraint of the phase field, which is severely hampered by the noise. Space-varying linear MMSE estimation is stated as a problem of matching pursuits, in which the estimator is obtained as an expansion in series of a finite number of prototype estimators, fitting the spatial features of the different statistical classes encountered, e.g., fringes, and steep slope areas. Such estimators are calculated in a fuzzy fashion through an automatic training procedure. The space-varying coefficients of the expansion are stated as degrees of fuzzy membership of a pixel to each of the estimators. Besides the fact that neither a priori knowledge on the noise variance is required, nor a particular signal model is assumed, a performance comparison on simulated noisy images highlights the advantages of the proposed approach. Results on simulated noisy versions of Lenna show a steady SNR improvement of almost 3 dB over Kuan's LLMMSE filtering, irrespective of noise model and intensity. Applications of the proposed filter to interferometric phase images demonstrate a superior ability of preserving fringes discontinuities, together with an effective smoothing performance, irrespective of local coherence characteristics.

  16. The ZpiM algorithm: a method for interferometric image reconstruction in SAR/SAS.

    PubMed

    Dias, José M B; Leitao, José M N

    2002-01-01

    This paper presents an effective algorithm for absolute phase (not simply modulo-2-pi) estimation from incomplete, noisy and modulo-2pi observations in interferometric aperture radar and sonar (InSAR/InSAS). The adopted framework is also representative of other applications such as optical interferometry, magnetic resonance imaging and diffraction tomography. The Bayesian viewpoint is adopted; the observation density is 2-pi-periodic and accounts for the interferometric pair decorrelation and system noise; the a priori probability of the absolute phase is modeled by a compound Gauss-Markov random field (CGMRF) tailored to piecewise smooth absolute phase images. We propose an iterative scheme for the computation of the maximum a posteriori probability (MAP) absolute phase estimate. Each iteration embodies a discrete optimization step (Z-step), implemented by network programming techniques and an iterative conditional modes (ICM) step (pi-step). Accordingly, the algorithm is termed ZpiM, where the letter M stands for maximization. An important contribution of the paper is the simultaneous implementation of phase unwrapping (inference of the 2pi-multiples) and smoothing (denoising of the observations). This improves considerably the accuracy of the absolute phase estimates compared to methods in which the data is low-pass filtered prior to unwrapping. A set of experimental results, comparing the proposed algorithm with alternative methods, illustrates the effectiveness of our approach. PMID:18244643

  17. The ZpiM algorithm: a method for interferometric image reconstruction in SAR/SAS.

    PubMed

    Dias, José M B; Leitao, José M N

    2002-01-01

    This paper presents an effective algorithm for absolute phase (not simply modulo-2-pi) estimation from incomplete, noisy and modulo-2pi observations in interferometric aperture radar and sonar (InSAR/InSAS). The adopted framework is also representative of other applications such as optical interferometry, magnetic resonance imaging and diffraction tomography. The Bayesian viewpoint is adopted; the observation density is 2-pi-periodic and accounts for the interferometric pair decorrelation and system noise; the a priori probability of the absolute phase is modeled by a compound Gauss-Markov random field (CGMRF) tailored to piecewise smooth absolute phase images. We propose an iterative scheme for the computation of the maximum a posteriori probability (MAP) absolute phase estimate. Each iteration embodies a discrete optimization step (Z-step), implemented by network programming techniques and an iterative conditional modes (ICM) step (pi-step). Accordingly, the algorithm is termed ZpiM, where the letter M stands for maximization. An important contribution of the paper is the simultaneous implementation of phase unwrapping (inference of the 2pi-multiples) and smoothing (denoising of the observations). This improves considerably the accuracy of the absolute phase estimates compared to methods in which the data is low-pass filtered prior to unwrapping. A set of experimental results, comparing the proposed algorithm with alternative methods, illustrates the effectiveness of our approach.

  18. A frequency domain radar interferometric imaging (FII) technique based on high-resolution methods

    NASA Astrophysics Data System (ADS)

    Luce, H.; Yamamoto, M.; Fukao, S.; Helal, D.; Crochet, M.

    2001-01-01

    In the present work, we propose a frequency-domain interferometric imaging (FII) technique for a better knowledge of the vertical distribution of the atmospheric scatterers detected by MST radars. This is an extension of the dual frequency-domain interferometry (FDI) technique to multiple frequencies. Its objective is to reduce the ambiguity (resulting from the use of only two adjacent frequencies), inherent with the FDI technique. Different methods, commonly used in antenna array processing, are first described within the context of application to the FII technique. These methods are the Fourier-based imaging, the Capon's and the singular value decomposition method used with the MUSIC algorithm. Some preliminary simulations and tests performed on data collected with the middle and upper atmosphere (MU) radar (Shigaraki, Japan) are also presented. This work is a first step in the developments of the FII technique which seems to be very promising.

  19. Non-interferometric quantitative phase imaging of yeast cells

    NASA Astrophysics Data System (ADS)

    Poola, Praveen K.; Pandiyan, Vimal Prabhu; John, Renu

    2015-12-01

    Real-time imaging of live cells is quite difficult without the addition of external contrast agents. Various methods for quantitative phase imaging of living cells have been proposed like digital holographic microscopy and diffraction phase microscopy. In this paper, we report theoretical and experimental results of quantitative phase imaging of live yeast cells with nanometric precision using transport of intensity equations (TIE). We demonstrate nanometric depth sensitivity in imaging live yeast cells using this technique. This technique being noninterferometric, does not need any coherent light sources and images can be captured through a regular bright-field microscope. This real-time imaging technique would deliver the depth or 3-D volume information of cells and is highly promising in real-time digital pathology applications, screening of pathogens and staging of diseases like malaria as it does not need any preprocessing of samples.

  20. The origin, history and future of fiber-optic interferometric acoustic sensors for US Navy applications

    NASA Astrophysics Data System (ADS)

    Cole, James H.; Bucaro, Joseph A.; Kirkendall, Clay K.; Dandridge, Anthony

    2011-05-01

    Fiber-optic interferometric acoustic sensors were first proposed for US Navy applications 36 years ago. This paper will review the origin, development and deployment of these sensors. Future applications will also be discussed.

  1. Interferometric Reflectance Imaging Sensor (IRIS)—A Platform Technology for Multiplexed Diagnostics and Digital Detection

    PubMed Central

    Avci, Oguzhan; Lortlar Ünlü, Nese; Yalçın Özkumur, Ayça; Ünlü, M. Selim

    2015-01-01

    Over the last decade, the growing need in disease diagnostics has stimulated rapid development of new technologies with unprecedented capabilities. Recent emerging infectious diseases and epidemics have revealed the shortcomings of existing diagnostics tools, and the necessity for further improvements. Optical biosensors can lay the foundations for future generation diagnostics by providing means to detect biomarkers in a highly sensitive, specific, quantitative and multiplexed fashion. Here, we review an optical sensing technology, Interferometric Reflectance Imaging Sensor (IRIS), and the relevant features of this multifunctional platform for quantitative, label-free and dynamic detection. We discuss two distinct modalities for IRIS: (i) low-magnification (ensemble biomolecular mass measurements) and (ii) high-magnification (digital detection of individual nanoparticles) along with their applications, including label-free detection of multiplexed protein chips, measurement of single nucleotide polymorphism, quantification of transcription factor DNA binding, and high sensitivity digital sensing and characterization of nanoparticles and viruses. PMID:26205273

  2. Optimal conditions for interferometric imaging maneuvers in near-earth orbit

    NASA Astrophysics Data System (ADS)

    Yoo, Sung-Moon; Jung, Taehyun

    Satellite formation flying has been extensively investigated as a way to expand the capabili-ties of space missions focused on obtaining interferometric images. The use of fleets of small satellites, instead of a single monolithic satellite, enables space interferometry with a capability of high resolution imaging through a reconfiguration maneuver. The goal of this study is to compute and analyze the optimal conditions of an n-spacecraft formation to obtain high-quality interferometric images in near-Earth orbit. In order to achieve an optimal performance in an interferometric imaging system, a fuel amount during reconfiguration maneuver and the imag-ing capability should be considered simultaneously. In the present study, a general analytic solution for the fuel-optimal reconfiguration of satellite formation flying is adapted. Based on the analytic solutions, the image-quality index is calculated for the case of various reconfgura-tion parameters, which are the size of the formation, the number of satellites and the maneuver durations. For the comparison of the image-quality index, we assumed a midinfrared system located at geostationary orbit, which has advantages in detecting human bodies and acquiring information that cannot be found by imaging in visible light, such as temperatures of buildings and hot spots where engines or machinery could be hidden. The results of simulations provide the optimal criteria of reconfiguration parameters to acquire high-quality interferometric im-ages. Optimal conditions determined in this work make it possible to design an overall concept for the reconfiguration maneuver of satellite formation to get an optimal interferometric image.

  3. Using dynamic interferometric synthetic aperature radar (InSAR) to image fast-moving surface waves

    DOEpatents

    Vincent, Paul

    2005-06-28

    A new differential technique and system for imaging dynamic (fast moving) surface waves using Dynamic Interferometric Synthetic Aperture Radar (InSAR) is introduced. This differential technique and system can sample the fast-moving surface displacement waves from a plurality of moving platform positions in either a repeat-pass single-antenna or a single-pass mode having a single-antenna dual-phase receiver or having dual physically separate antennas, and reconstruct a plurality of phase differentials from a plurality of platform positions to produce a series of desired interferometric images of the fast moving waves.

  4. Rapid interferometric imaging of printed drug laden multilayer structures

    PubMed Central

    Sandler, Niklas; Kassamakov, Ivan; Ehlers, Henrik; Genina, Natalja; Ylitalo, Tuomo; Haeggstrom, Edward

    2014-01-01

    The developments in printing technologies allow fabrication of micron-size nano-layered delivery systems to personal specifications. In this study we fabricated layered polymer structures for drug-delivery into a microfluidic channel and aimed to interferometrically assure their topography and adherence to each other. We present a scanning white light interferometer (SWLI) method for quantitative assurance of the topography of the embedded structure. We determined rapidly in non-destructive manner the thickness and roughness of the structures and whether the printed layers containing polymers or/and active pharmaceutical ingredients (API) adhere to each other. This is crucial in order to have predetermined drug release profiles. We also demonstrate non-invasive measurement of a polymer structure in a microfluidic channel. It shown that traceable interferometric 3D microscopy is a viable technique for detailed structural quality assurance of layered drug-delivery systems. The approach can have impact and find use in a much broader setting within and outside life sciences. PMID:24503863

  5. Rapid interferometric imaging of printed drug laden multilayer structures.

    PubMed

    Sandler, Niklas; Kassamakov, Ivan; Ehlers, Henrik; Genina, Natalja; Ylitalo, Tuomo; Haeggstrom, Edward

    2014-01-01

    The developments in printing technologies allow fabrication of micron-size nano-layered delivery systems to personal specifications. In this study we fabricated layered polymer structures for drug-delivery into a microfluidic channel and aimed to interferometrically assure their topography and adherence to each other. We present a scanning white light interferometer (SWLI) method for quantitative assurance of the topography of the embedded structure. We determined rapidly in non-destructive manner the thickness and roughness of the structures and whether the printed layers containing polymers or/and active pharmaceutical ingredients (API) adhere to each other. This is crucial in order to have predetermined drug release profiles. We also demonstrate non-invasive measurement of a polymer structure in a microfluidic channel. It shown that traceable interferometric 3D microscopy is a viable technique for detailed structural quality assurance of layered drug-delivery systems. The approach can have impact and find use in a much broader setting within and outside life sciences.

  6. Interferometric and optical tests of water window imaging x ray microscopes

    NASA Technical Reports Server (NTRS)

    Johnson, R. Barry

    1993-01-01

    Interferometric tests of Schwarzchild X-ray Microscope are performed to evaluate the optical properties and alignment of the components. Photographic measurements of the spatial resolution, focal properties, and vignetting characteristics of the prototype Water Window Imaging X-ray Microscope are made and analyzed.

  7. Interferometric imaging of crustal structure from wide-angle multicomponent OBS-airgun data

    NASA Astrophysics Data System (ADS)

    Shiraishi, K.; Fujie, G.; Sato, T.; Abe, S.; Asakawa, E.; Kodaira, S.

    2015-12-01

    In wide-angle seismic surveys with ocean bottom seismograph (OBS) and airgun, surface-related multiple reflections and upgoing P-to-S conversions are frequently observed. We applied two interferometric imaging methods to the multicomponent OBS data in order to highly utilize seismic signals for subsurface imaging.First, seismic interferometry (SI) is applied to vertical component in order to obtain reflection profile with multiple reflections. By correlating seismic traces on common receiver records, pseudo seismic data are generated with virtual sources and receivers located on all original shot positions. We adopt the deconvolution SI because source and receiver spectra can be canceled by spectral division. Consequently, gapless reflection images from just below the seafloor to the deeper are obtained.Second, receiver function (RF) imaging is applied to multicomponent OBS data in order to image P-to-S conversion boundary. Though RF is commonly applied to teleseismic data, our purpose is to extract upgoing PS converted waves from wide-angle OBS data. The RF traces are synthesized by deconvolution of radial and vertical components at same OBS location for each shot. Final section obtained by stacking RF traces shows the PS conversion boundaries beneath OBSs. Then, Vp/Vs ratio can be estimated by comparing one-way traveltime delay with two-way traveltime of P wave reflections.We applied these methods to field data sets; (a) 175 km survey in Nankai trough subduction zone using 71 OBSs with from 1 km to 10 km intervals and 878 shots with 200 m interval, and (b) 237 km survey in northwest pacific ocean with almost flat layers before subduction using 25 OBSs with 6km interval and 1188 shots with 200 m interval. In our study, SI imaging with multiple reflections is highly applicable to OBS data even in a complex geological setting, and PS conversion boundary is well imaged by RF imaging and Vp/Vs ratio distribution in sediment is estimated in case of simple structure.

  8. Robust interferometric imaging via prior-less phase recovery: redundant spacing calibration with generalized closure phases

    NASA Astrophysics Data System (ADS)

    Kurien, Binoy G.; Ashcom, Jonathan B.; Shah, Vinay N.; Rachlin, Yaron; Tarokh, Vahid

    2016-09-01

    Atmospheric turbulence presents a fundamental challenge to Fourier phase recovery in optical interferometry. Typical reconstruction algorithms employ Bayesian inference techniques which rely on prior knowledge of the scene under observation. In contrast, Redundant Spacing Calibration (RSC) algorithms employ redundancy in the baselines of the interferometric array to directly expose the contribution of turbulence, thereby enabling phase recovery for targets of arbitrary and unknown complexity. Traditionally RSC algorithms have been applied directly to single-exposure measurements, which are reliable only at high photon flux in general. In scenarios of low photon flux, such as those arising in the observation of dim objects in space, one must instead rely on time-averaged, atmosphere-invariant quantities such as the bispectrum. In this paper, we develop a novel RSC-based algorithm for prior-less phase recovery in which we generalize the bispectrum to higher-order atmosphere-invariants (n-spectra) for improved sensitivity. We provide a strategy for selection of a high-SNR set of n-spectra using the graph-theoretic notion of the minimum cycle basis. We also discuss a key property of this set (wrap-invariance), which then enables reliable application of standard linear estimation techniques to recover the Fourier phases from the 2π-wrapped n-spectra phases. For validation, we analyze the expected shot-noise-limited performance of our algorithm for both pairwise and Fizeau interferometric architectures, and corroborate this analysis with simulation results showing performance near an atmosphere-oracle Cramer-Rao bound. Lastly, we apply techniques from the field of compressed sensing to perform image reconstruction from the estimated complex visibilities.

  9. Simultaneous interferometric in-focus and out-of-focus imaging of ice crystals

    NASA Astrophysics Data System (ADS)

    Kielar, Justin Jacquot; Lemaitre, Pascal; Gobin, Carole; Yingchun, Wu; Porcheron, Emmanuel; Coetmellec, Sébastien; Grehan, Gérard; Brunel, Marc

    2016-08-01

    Using a freezing column, dendrite-like ice crystals are generated and characterized simultaneously using in-focus imaging and interferometric out-of-focus imaging. This simultaneous analysis allows a validation of size measurements made from the analysis of the 2D-autocorrelation of speckle-like interferometric out-of-focus patterns of ice crystals. Measurements of the same particles by in-focus and out-of-focus techniques are in good agreement for 75% of the particles tested. Simulations of out-of-focus patterns are in very good agreement with experimental images. The analysis of the 2D-Fourier transform of the speckle-like patterns confirms that it is possible to evaluate the 2D-autocorrelation of the global shape of the particle (i.e. its 2D-projection on the plane of the CCD sensor).

  10. 3D spatial resolution and spectral resolution of interferometric 3D imaging spectrometry.

    PubMed

    Obara, Masaki; Yoshimori, Kyu

    2016-04-01

    Recently developed interferometric 3D imaging spectrometry (J. Opt. Soc. Am A18, 765 [2001]1084-7529JOAOD610.1364/JOSAA.18.000765) enables obtainment of the spectral information and 3D spatial information for incoherently illuminated or self-luminous object simultaneously. Using this method, we can obtain multispectral components of complex holograms, which correspond directly to the phase distribution of the wavefronts propagated from the polychromatic object. This paper focuses on the analysis of spectral resolution and 3D spatial resolution in interferometric 3D imaging spectrometry. Our analysis is based on a novel analytical impulse response function defined over four-dimensional space. We found that the experimental results agree well with the theoretical prediction. This work also suggests a new criterion and estimate method regarding 3D spatial resolution of digital holography. PMID:27139648

  11. Optoacoustic imaging using interferometric measurement of surface displacement

    SciTech Connect

    Carp, Stefan A.; Guerra, Arnold III; Duque, Samuel Q. Jr.; Venugopalan, Vasan

    2004-12-06

    We describe an optoacoustic imaging technique based on time-resolved measurements of laser-induced thermoelastic expansion. Tomographic images of tissue phantoms are formed using such measurements made at several locations following irradiation with a Q-switched Nd:YAG ({lambda}=1064 nm) laser pulse. Our system is based on a modified Mach-Zehnder interferometer that measures surface displacement with a temporal resolution of 4 ns and a displacement sensitivity of 0.3 nm. Images formed from data sets acquired from several highly scattering tissue phantoms provide better than 200 {mu}m resolution and show great promise for high-resolution noninvasive imaging of heterogeneous tissues at depths approaching 1 cm.

  12. Imaging and interferometric analysis of protein crystal growth

    NASA Astrophysics Data System (ADS)

    Raghunandan, Ranjini; Gupta, Anamika Sethia; Muralidhar, K.

    2008-04-01

    Protein crystals are grown under controlled temperature, concentration and vapor pressure conditions, usually by vapor diffusion, liquid-liquid diffusion and dialysis techniques. The present study examines the effects of protein concentration, drop size and reservoir height on the crystal growth of Hen Egg White Lysozyme (HEWL). Crystals are grown by the hanging drop vapor diffusion method using Modular VDX TM Plates. Due to the vapor pressure difference created between the protein drop and the reservoir, evaporation takes place till equilibrium is attained. Crystal formation takes place after a certain level of supersaturation is attained when the protein precipitates out in crystalline form. The observations revealed that the growth is faster for higher lysozyme concentration, smaller drop sizes and larger reservoir heights. The morphology of the crystals is viewed during the growth process using stereomicroscope. The number of crystals formed is the maximum for higher concentrations, drop sizes and reservoir heights. When the number of crystals formed is less, the size of the crystals is comparatively larger. The effect of evaporation of water vapor from the protein drop into the reservoir is studied using Mach-Zehnder interferometry. The recorded interferograms and shadowgraph images indicate the diffusion of condensed water into the reservoir. The radius of the drop is determined using the shadowgraph images of the growth process. The radius decreases with evaporation and the rate of decrease of radius is highest for higher protein concentrations, smaller drop sizes and larger reservoir heights.

  13. Radar-Interferometric Imaging of Near Earth Asteroids

    NASA Astrophysics Data System (ADS)

    Black, G.; Campbell, D.

    2003-05-01

    We report on progress to use a radio interferometer, the NRAO Very Long Baseline Array (VLBA), to image near Earth asteroids as they are illuminated by the Arecibo Observatory's S-band radar. By measuring the plane-of-sky brightness distribution of the target under the radar's illumination, this method will be able to provide direct, unambiguous spatial resolution of order 100 m which for many objects is sufficient to grossly define their shape, map large scale reflectivity variations, and measure the absolute orientation of the projected spin axis. With receiving antenna spacings of several thousands of kilometers, the potential resolution obtainable with the VLBA at the Arecibo wavelength of 13 cm is on the order of a few milli-arcseconds; several orders of magnitude smaller than typical ground-based telescopic observations. In addition, astrometry of these quickly moving objects at this milli-arcsecond level can greatly reduce orbit uncertainties. This technique has been used to observe two near Earth asteroids, 2000 EW70 and 2002 NY40, during their recent close passes to Earth. The first asteroid was clearly detected; however, a useful correlation on either object is still in progress. A major limitation is the configuration of the hardware correlator which doesn't allow adequate frequency resolution and complicates incorporating a model of the near-field geometry. A solution to these difficulties is now available as a specialized computer interface designed to transfer the raw data into a portable format thereby bypassing the correlator and allowing for a more flexible correlation in software on another platform. Testing of this machine and the subsequent software correlation are currently underway. The National Radio Astronomy Observatory (NRAO) is a facility of the NSF operated under cooperative agreement by Associated Universities, Inc. The Arecibo Observatory is part of the National Astronomy and Ionosphere Center, which is operated by Cornell University

  14. Interferometric synthetic aperture radar detection and estimation based 3D image reconstruction

    NASA Astrophysics Data System (ADS)

    Austin, Christian D.; Moses, Randolph L.

    2006-05-01

    This paper explores three-dimensional (3D) interferometric synthetic aperture radar (IFSAR) image reconstruction when multiple scattering centers and noise are present in a radar resolution cell. We introduce an IFSAR scattering model that accounts for both multiple scattering centers and noise. The problem of 3D image reconstruction is then posed as a multiple hypothesis detection and estimation problem; resolution cells containing a single scattering center are detected and the 3D location of these cells' pixels are estimated; all other pixels are rejected from the image. Detection and estimation statistics are derived using the multiple scattering center IFSAR model. A 3D image reconstruction algorithm using these statistics is then presented, and its performance is evaluated for a 3D reconstruction of a backhoe from noisy IFSAR data.

  15. Direct and interferometric imaging approaches for detecting earth-like extrasolar planets

    NASA Technical Reports Server (NTRS)

    Diner, D. J.; Van Zyl, J.; Jones, D. L.; Tubbs, E.; Wright, V.

    1988-01-01

    This paper discusses functional requirements of space-based observational systems with sufficient sensitivity, resolution, and dynamic range to image earth-like extrasolar planets within a search radius of 10 parsecs from the sun. Both direct and interferometric systems operating at visible and infrared wavelengths are evaluated, and the methods used to establish the system tolerances are presented. Due to the more favorable star/planet contrast ratio in the infrared, optical tolerance requirements are less stringent than in the visible. However, reduction of thermal radiation from the telescope requires cooling of the primary optics. Other tradeoffs between various approaches are enumerated.

  16. Experimental performance of homothetic mapping for wide-field interferometric imaging

    NASA Astrophysics Data System (ADS)

    van der Avoort, Casper; van Brug, Hedser; den Herder, Jan-Willem; D'Arcio, Luigi L.; Le Poole, Rudolf S.; Braat, Joseph J.

    2004-10-01

    Homothetic mapping is an aperture synthesis technique that allows interferometric imaging over a wide field-of-view. A laboratory experiment was set up to demonstrate the feasibility of this technique. Here, we present the first static experiments on homothetic mapping that have been done on the Delft Testbed for Interferometry (DTI). Before a changeable telescope configuration is provided, we first took a fixed telescope configuration and tested the algorithms for their ability to provide an exit pupil configuration before beam combination, that was an exact copy of this telescope configuration. By doing so, we created a homothetic imaging system. This is an imaging system that acts as a masked aperture monolithic telescope, but consists of (in our case) three telescopes of which the light follow their own optical trains.

  17. Improving image quality in intensity-interferometric spectral-domain optical coherence tomography

    NASA Astrophysics Data System (ADS)

    Shirai, Tomohiro

    2016-07-01

    Intensity-interferometric spectral-domain optical coherence tomography (I-SD-OCT), devised recently as a classical analog of quantum OCT, enables axially scanless cross-sectional imaging with an immunity to group-velocity dispersion and a factor-of-\\sqrt{2} resolution improvement. However, unwanted artifacts inevitably emerge in the resultant image. In this paper, it is demonstrated theoretically and experimentally that such artifacts can be reduced without any difficulty by means of either a mechanical displacement of the detector for capturing spectral intensity patterns or a numerical displacement of the spectral intensity patterns stored in a computer. Furthermore, it is proved that the I-SD-OCT signal can be extracted from the conventional SD-OCT setup under a certain condition. These two features serve to improve the image quality in I-SD-OCT.

  18. Computed optical interferometric tomography for high-speed volumetric cellular imaging

    PubMed Central

    Liu, Yuan-Zhi; Shemonski, Nathan D.; Adie, Steven G.; Ahmad, Adeel; Bower, Andrew J.; Carney, P. Scott; Boppart, Stephen A.

    2014-01-01

    Three-dimensional high-resolution imaging methods are important for cellular-level research. Optical coherence microscopy (OCM) is a low-coherence-based interferometry technology for cellular imaging with both high axial and lateral resolution. Using a high-numerical-aperture objective, OCM normally has a shallow depth of field and requires scanning the focus through the entire region of interest to perform volumetric imaging. With a higher-numerical-aperture objective, the image quality of OCM is affected by and more sensitive to aberrations. Interferometric synthetic aperture microscopy (ISAM) and computational adaptive optics (CAO) are computed imaging techniques that overcome the depth-of-field limitation and the effect of optical aberrations in optical coherence tomography (OCT), respectively. In this work we combine OCM with ISAM and CAO to achieve high-speed volumetric cellular imaging. Experimental imaging results of ex vivo human breast tissue, ex vivo mouse brain tissue, in vitro fibroblast cells in 3D scaffolds, and in vivo human skin demonstrate the significant potential of this technique for high-speed volumetric cellular imaging. PMID:25401012

  19. Application of holographic interferometric studies of underwater shock-wave focusing to medicine

    NASA Astrophysics Data System (ADS)

    Takayama, Kazuyoshi; Nagoya, H.; Obara, Tetsuro; Kuwahara, M.

    1993-01-01

    Holographic interferometric flow visualization was successfully applied to underwater shock wave focusing and its application to extracorporeal shock wave lithotripsy (ESWL). Real time diffuse holograms revealed the shock wave focusing process in an ellipsoidal reflector made from PMMA and double exposure holographic interferometry also clarified quantitatively the shock focusing process. Disintegration of urinary tract stones and gallbladder stones was observed by high speed photogrammetry. Tissue damage associated with the ESWL treatment is discussed in some detail.

  20. THE AzTEC/SMA INTERFEROMETRIC IMAGING SURVEY OF SUBMILLIMETER-SELECTED HIGH-REDSHIFT GALAXIES

    SciTech Connect

    Younger, Joshua D.; Fazio, Giovanni G.; Huang Jiasheng; Ashby, Matthew L. N.; Gurwell, Mark A.; Petitpas, Glen R.; Wilner, David J.; Yun, Min S.; Wilson, Grant W.; Scott, Kimberly S.; Austermann, Jason; Perera, Thushara; Peck, Alison B.; Hughes, David H.; Aretxaga, Itziar; Kim, Sungeun; Lowenthal, James D.

    2009-10-10

    We present results from a continuing interferometric survey of high-redshift submillimeter galaxies (SMGs) with the Submillimeter Array, including high-resolution (beam size approx2 arcsec) imaging of eight additional AzTEC 1.1 mm selected sources in the COSMOS field, for which we obtain six reliable (peak signal-to-noise ratio (S/N) >5 or peak S/N >4 with multiwavelength counterparts within the beam) and two moderate significance (peak S/N >4) detections. When combined with previous detections, this yields an unbiased sample of millimeter-selected SMGs with complete interferometric follow up. With this sample in hand, we (1) empirically confirm the radio-submillimeter association, (2) examine the submillimeter morphology-including the nature of SMGs with multiple radio counterparts and constraints on the physical scale of the far infrared-of the sample, and (3) find additional evidence for a population of extremely luminous, radio-dim SMGs that peaks at higher redshift than previous, radio-selected samples. In particular, the presence of such a population of high-redshift sources has important consequences for models of galaxy formation-which struggle to account for such objects even under liberal assumptions-and dust production models given the limited time since the big bang.

  1. Scalable splitting algorithms for big-data interferometric imaging in the SKA era

    NASA Astrophysics Data System (ADS)

    Onose, Alexandru; Carrillo, Rafael E.; Repetti, Audrey; McEwen, Jason D.; Thiran, Jean-Philippe; Pesquet, Jean-Christophe; Wiaux, Yves

    2016-11-01

    In the context of next-generation radio telescopes, like the Square Kilometre Array (SKA), the efficient processing of large-scale data sets is extremely important. Convex optimization tasks under the compressive sensing framework have recently emerged and provide both enhanced image reconstruction quality and scalability to increasingly larger data sets. We focus herein mainly on scalability and propose two new convex optimization algorithmic structures able to solve the convex optimization tasks arising in radio-interferometric imaging. They rely on proximal splitting and forward-backward iterations and can be seen, by analogy, with the CLEAN major-minor cycle, as running sophisticated CLEAN-like iterations in parallel in multiple data, prior, and image spaces. Both methods support any convex regularization function, in particular, the well-studied ℓ1 priors promoting image sparsity in an adequate domain. Tailored for big-data, they employ parallel and distributed computations to achieve scalability, in terms of memory and computational requirements. One of them also exploits randomization, over data blocks at each iteration, offering further flexibility. We present simulation results showing the feasibility of the proposed methods as well as their advantages compared to state-of-the-art algorithmic solvers. Our MATLAB code is available online on GitHub.

  2. Quasi real-time analysis of mixed-phase clouds using interferometric out-of-focus imaging: development of an algorithm to assess liquid and ice water content

    NASA Astrophysics Data System (ADS)

    Lemaitre, P.; Brunel, M.; Rondeau, A.; Porcheron, E.; Gréhan, G.

    2015-12-01

    According to changes in aircraft certifications rules, instrumentation has to be developed to alert the flight crews of potential icing conditions. The technique developed needs to measure in real time the amount of ice and liquid water encountered by the plane. Interferometric imaging offers an interesting solution: It is currently used to measure the size of regular droplets, and it can further measure the size of irregular particles from the analysis of their speckle-like out-of-focus images. However, conventional image processing needs to be speeded up to be compatible with the real-time detection of icing conditions. This article presents the development of an optimised algorithm to accelerate image processing. The algorithm proposed is based on the detection of each interferogram with the use of the gradient pair vector method. This method is shown to be 13 times faster than the conventional Hough transform. The algorithm is validated on synthetic images of mixed phase clouds, and finally tested and validated in laboratory conditions. This algorithm should have important applications in the size measurement of droplets and ice particles for aircraft safety, cloud microphysics investigation, and more generally in the real-time analysis of triphasic flows using interferometric particle imaging.

  3. Plastic mine detecting radar system using complex-valued self-organizing map that deals with multiple-frequency interferometric images.

    PubMed

    Hara, Takahiro; Hirose, Akira

    2004-01-01

    Ground penetrating radars (GPR's) have been often applied to underground object imaging. However, conventional radar systems do not work sufficiently to detect anti-personnel plastic landmines. We propose a novel radar imaging system, which processes adaptively interferometric front-end data obtained at multiple-frequency points. The system deals with interferometric images using complex-valued self-organizing map (C-SOM). We demonstrate a successful visualization of a plastic mine buried near the ground surface. PMID:15555861

  4. COLDER AND HOTTER: INTERFEROMETRIC IMAGING OF {beta} CASSIOPEIAE AND {alpha} LEONIS

    SciTech Connect

    Che, X.; Monnier, J. D.; Zhao, M.; Merand, A.; Ten Brummelaar, T.; McAlister, H.; Turner, N.; Sturmann, J.; Sturmann, L.; Ridgway, S. T.

    2011-05-10

    Near-infrared interferometers have recently imaged a number of rapidly rotating A-type stars, finding levels of gravity darkening inconsistent with theoretical expectations. Here, we present new imaging of both a cooler star {beta} Cas (F2IV) and a hotter one {alpha} Leo (B7V) using the CHARA array and the MIRC instrument at the H band. Adopting a solid-body rotation model with a simple gravity darkening prescription, we modeled the stellar geometric properties and surface temperature distributions, confirming that both stars are rapidly rotating and show gravity darkening anomalies. We estimate the masses and ages of these rapid rotators on L-R{sub pol} and H-R diagrams constructed for non-rotating stars by tracking their non-rotating equivalents. The unexpected fast rotation of the evolved sub-giant {beta} Cas offers a unique test of the stellar core-envelope coupling, revealing quite efficient coupling over the past {approx}0.5 Gyr. Lastly, we summarize all our interferometric determinations of the gravity darkening coefficient for rapid rotators, finding that none match the expectations from the widely used von Zeipel gravity darkening laws. Since the conditions of the von Zeipel law are known to be violated for rapidly rotating stars, we recommend using the empirically derived {beta} = 0.19 for such stars with radiation-dominated envelopes. Furthermore, we note that no paradigm exists for self-consistently modeling heavily gravity-darkened stars that show hot radiative poles with cool convective equators.

  5. 3D interferometric microscope: color visualization of engineered surfaces for industrial applications

    NASA Astrophysics Data System (ADS)

    Schmit, Joanna; Novak, Matt; Bui, Son

    2015-09-01

    3D microscopes based on white light interference (WLI) provide precise measurement for the topography of engineering surfaces. However, the display of an object in its true colors as observed under white illumination is often desired; this traditionally has presented a challenge for WLI-based microscopes. Such 3D color display is appealing to the eye and great for presentations, and also provides fast evaluation of certain characteristics like defects, delamination, or deposition of different materials. Determination of color as observed by interferometric objectives is not straightforward; we will present how color imaging capabilities similar to an ordinary microscope can be obtained in interference microscopes based on WLI and we will give measurement and imaging examples of a few industrial samples.

  6. Advanced Interferometric Synthetic Aperture Imaging Radar (InSAR) for Dune Mapping

    NASA Astrophysics Data System (ADS)

    Havivi, Shiran; Amir, Doron; Schvartzman, Ilan; August, Yitzhak; Mamman, Shimrit; Rotman, Stanely R.; Blumberg, Dan G.

    2016-04-01

    Aeolian morphologies are formed in the presence of sufficient wind energy and available lose particles. These processes occur naturally or are further enhanced or reduced by human intervention. The dimensions of change are dependent primarily on the wind energy and surface properties. Since the 1970s, remote sensing imagery, both optical and radar, have been used for documentation and interpretation of the geomorphologic changes of sand dunes. Remote sensing studies of aeolian morphologies is mostly useful to document major changes, yet, subtle changes, occurring in a period of days or months in scales of centimeters, are very difficult to detect in imagery. Interferometric Synthetic Aperture Radar (InSAR) is an imaging technique for measuring Earth's surface topography and deformation. InSAR images are produced by measuring the radar phase difference between two separated antennas that view the same surface area. Classical InSAR is based on high coherence between two or more images. The output (interferogram) can show subtle changes with an accuracy of several millimeters to centimeters. Very little work has been done on measuring or identifying the changes in dunes using InSAR methods. The reason is that dunes tend to be less coherent than firm, stable, surfaces. This work aims to demonstrate how interferometric decorrelation can be used for identifying dune instability. We hypothesize and demonstrate that the loss of radar coherence over time on dunes can be used as an indication of the dune's instability. When SAR images are acquired at sufficiently close intervals one can measure the time it takes to lose coherence and associate this time with geomorphic stability. To achieve our goals, the coherence change detection method was used, in order to identify dune stability or instability and the dune activity level. The Nitzanim-Ashdod coastal dunes along the Mediterranean, 40 km south of Tel-Aviv, Israel, were chosen as a case study. The dunes in this area are of

  7. An Interferometric Reflectance Imaging Sensor for Point of Care Viral Diagnostics

    PubMed Central

    Reddington, Alexander P.; Trueb, Jacob T.; Freedman, David S.; Tuysuzoglu, Ahmet; Daaboul, George G.; Lopez, Carlos A.; Karl, W. Clem; Connor, John H.; Fawcett, Helen; Ünlü, M. Selim

    2014-01-01

    The use of in vitro diagnostic devices is transitioning from the laboratory to the primary care setting to address early disease detection needs. Time critical viral diagnoses are often made without support due to the experimental time required in today’s standard tests. Available rapid point of care (POC) viral tests are less reliable, requiring a follow-on confirmatory test before conclusions can be drawn. The development of a reliable POC viral test for the primary care setting would decrease the time for diagnosis leading to a lower chance of transmission and improve recovery. The single particle interferometric reflectance imaging sensor (SP-IRIS) has been shown to be a sensitive and specific-detection platform in serum and whole blood. This paper presents a step towards a POC viral assay through a SP-IRIS prototype with automated data acquisition and analysis and a simple, easy-to-use software interface. Decreasing operation complexity highlights the potential of SP-IRIS as a sensitive and specific POC diagnostic tool. With the integration of a microfluidic cartridge, this automated instrument will allow an untrained user to run a sample-to-answer viral assay in the POC setting. PMID:24271115

  8. The Age of the Directly Imaged Planet Host Star κ Andromedae Determined from Interferometric Observations

    NASA Astrophysics Data System (ADS)

    Jones, Jeremy; White, R. J.; Quinn, S.; Ireland, M.; Boyajian, T.; Schaefer, G.; Baines, E. K.

    2016-05-01

    κ Andromedae, an early-type star that hosts a directly imaged low-mass companion, is expected to be oblate due to its rapid rotational velocity (v sin i = ˜162 km s‑1). We observed the star with the CHARA Array’s optical beam combiner, PAVO, measuring its size at multiple orientations and determining its oblateness. The interferometric measurements, combined with photometry and this v sin i value are used to constrain an oblate star model that yields the fundamental properties of the star and finds a rotation speed that is ˜85% of the critical rate and a low inclination of ˜30°. Three modeled properties (the average radius, bolometric luminosity, and equatorial velocity) are compared to MESA evolution models to determine an age and mass for the star. In doing so, we determine an age for the system of {47}-40+27 Myr. Based on this age and previous measurements of the companion’s temperature, the BHAC15 evolution models imply a mass for the companion of {22}-9+8 M J.

  9. Extended radar observations with the frequency radar domain interferometric imaging (FII) technique

    NASA Astrophysics Data System (ADS)

    Luce, H.; Yamamoto, M.; Fukao, S.; Crochet, M.

    2001-07-01

    In this paper, we present high-resolution observations obtained with the Middle and Upper Atmosphere (MU) radar (Shigaraki, Japan, /34.85°N, /136.10°E) using the frequency radar domain interferometric imaging (FII) technique. This technique has recently been introduced for improving the range resolution capabilities of the mesosphere-stratosphere-troposphere (MST) radars which are limited by their minimum pulse length. The Fourier-based imaging, the Capon method have been performed with 5 equally spaced frequencies between 46.25 and 46.75MHz and with an initial range resolution of 300m. These results have been compared firstly to results obtained using the frequency domain interferometry (FDI) technique with Δf=0.5MHz and, secondly, to results from a classical Doppler beam swinging (DBS) mode applied with a range resolution of 150m. Thin echoing structures could be tracked owing to the improved radar range resolution and some complex structures possibly related to Kelvin Helmholtz instabilities have been detected. Indeed, these structures appeared within the core of a wind shear and were associated with intense vertical wind fluctuations. Moreover, a well-defined thin echo layer was found in an altitude range located below the height of the wind shear. The radar observations have not been fully interpreted yet because the radar configuration was not adapted for this kind of study and because of the lack of complementary information provided by other techniques when the interesting echoing phenomena occurred. However, the results confirm the high potentialities of the FII technique for the study of atmospheric dynamics at small scales.

  10. Sapce based low frequency interferometric radioastronomy: the path towards the imaging of the inner heliosphere.

    NASA Astrophysics Data System (ADS)

    Cecconi, B.; Zarka, P. M.; Girard, J. N.; Klein Wolt, M.; Boonstra, A. J.; Baan, W.; Briand, C.; Maksimovic, M.; Segret, B.

    2014-12-01

    Low frequency radioastronomy observatories for the heliosphere have been using similar instrumentation for decades. The Cassini, STEREO, and the future Solar Orbiter mission are embarking goniopolarmetric radio receiver connected to 3 electric wire antennas. Such instrument provides the spectral matrix (or part of it) from which the wave parameters can be derived. They require a point source assumption (plane wave) to derive the direction of arrival of the wave, the polarization and the flux density. In case of a spatially extended source (disk shaped, with a given radial profile), the source centroid direction and the apparent source size can also be derived. This type of instrumentation cannot provide much more parameters, as there is a maximum of to 9 independent measurements for each time-frequency step (i.e. an instantaneous set of measurements). Radio maps can be produced a posteriori combining consecutive data at the cost of averaging out small scale temporal variations. Furthermore, these inversion do not allow solving for several sources, or for complex source geometry. We present a concept of radioastronomy instrumentation using a swarm of small satellites (possibly cubesats) with sensitive radio receivers measuring the wave front and phase of the radio waves on each spacecraft. This instrument will also provide 3-dimensional interferometric measurement from which real imaging capabilities will arise, as it is now occurring on ground at frequencies above 15 MHz, with the LOFAR interferometer in Europe, or the LWA in teh USA. The proposed concept will be very complementary to these instruments, as they will be orepating from a few kHz to a few 10 Mhz from space, and thus not affected by the ionospheric cutoff at 10 MHz. Such resolved imaging capabilities of the inner heliosphere would be a real step forward to better understand the radio emissions mechanisms and the energetic at the orgin of the radio sources, as well as the propagation processes. We will

  11. Interferometric properties of standing spin waves and the application to a phase comparator

    SciTech Connect

    Ya, X.; Chen, H.; Oyabu, S.; Peng, B.; Otsuki, H.; Tanaka, T. Matsuyama, K.

    2015-05-07

    We numerically studied the material and structural parameter dependence of interferometric properties of the standing spin wave resonance (SSWR) by micromagnetic simulations and demonstrate the feasibility of practical application to an integrated phase comparator. The micromagnetic configuration of the synthesized SSWR emitted from the two microwave currents flowing through the parallel strip lines depends on the phase difference Δϕ between them. Resultantly, the Δϕ is converted to the related output voltage with an overlaid phase detector, inductively coupled to the magnetic strip. Among the investigated various material systems, low damping (α ∼ 0.001) metallic ferromagnets are found to exhibit superior device performance due to the reduced viscous dissipation.

  12. Applications of computer-generated holograms for interferometric measurement of large aspheric optics

    NASA Astrophysics Data System (ADS)

    Burge, James H.

    1995-08-01

    Interferometric optical testing using computer-generated holograms (CGH's) has proven to give highly accurate measurements of aspheric surfaces. New applications of CGH interferometry were developed to support the fabrication of the large, steep mirrors required by the next generation ground-based telescopes. A new test to certify null correctors was designed and implemented that uses small CGH's fabricated onto flat surfaces. This test solves the difficult problem of verifying the accuracy of the null correctors that are used for measuring primary mirrors. Several new techniques for hologram fabrication have been explored for this application. A second new use of CGH's was developed for measuring convex secondary mirrors using test plates with holograms fabricated onto concave spherical reference surfaces. This test provides efficient and accurate measurement of large aspheric convex mirrors. A polar coordinate laser writing machine was built for fabricating these patterns onto curved optical surfaces up to 1.8 meters in diameter and as fast as f/1. These powerful new techniques have been implemented and optimized at the Steward Observatory Mirror Laboratory to guide mirror polishing for large telescope projects. They can also be readily applied for measuring small aspheres to high accuracy.

  13. Tunable coherent radiation at soft X-ray wavelengths: Generation and interferometric applications

    SciTech Connect

    Rosfjord, Kristine Marie

    2004-07-01

    The availability of high power, spectrally and spatially coherent soft x-rays (SXR) would facilitate a wide variety of experiments as this energy region covers the primary resonances of many magnetic and biological materials. Specifically, there are the carbon and oxygen K-edges that are critical for biological imaging in the water window and the L-edges of iron, nickel, and cobalt for which imaging and scattering studies can be performed. A new coherent soft X-ray branchline at the Advanced Light Source has begun operation (beamline 12.0.2). Using the third harmonic from an 8 cm period undulator, this branch delivers coherent soft x-rays with photon energies ranging from 200eV to 1keV. This branchline is composed of two sub-branches one at 14X demagnification and the other 8X demagnification. The former is optimized for use at 500eV and the latter at 800eV. Here the expected power from the third harmonic of this undulator and the beamline design and characterization is presented. The characterization includes measurements on available photon flux as well as a series of double pinhole experiments to determine the coherence factor with respect to transverse distance. The first high quality Airy patterns at SXR wavelengths are created with this new beamline. The operation of this new beamline allows for interferometry to be performed in the SXR region. Here an interferometric experiment designed to directly determine the index of refraction of a material under test is performed. Measurements are first made in the EUV region using an established beamline (beamline12.0.1) to measure silicon, ruthenium and tantalum silicon nitride. This work is then extended to the SXR region using beamline 12.0.2 to test chromium and vanadium.

  14. Development of a folded compact range and its application in performing coherent change detection and interferometric ISAR measurement

    SciTech Connect

    Sorensen, K.W.; Zittel, D.H.; Littlejohn, J.H.

    1996-09-01

    A folded compact range configuration has been developed at the Sandia National Laboratories` compact range antenna and radar cross section measurement facility as a means of performing indoor, environmentally controlled far-field simulations of synthetic aperture radar (SAR) measurements of distributed target samples (i.e. gravel, sand, etc.). In particular, the folded compact range configuration has been used to perform both highly sensitive coherent change detection (CCD) measurements and interferometric inverse synthetic aperture radar (IFSAR) measurements, which, in addition to the two-dimensional spatial resolution afforded by typical interferometric SAR (ISAR) processing, provides resolution of the relative height of targets with accuracies on the order of a wavelength. This paper describes the development of the folded compact range, as well as the coherent change detection and interferometric measurements that have been made with the system. The measurement have been very successful, and have demonstrated not only the viability of the folded compact range concept in simulating SAR CCD and IFSAR measurements, but also its usefulness as a tool in the research and development of SAR CCD and IFSAR image generation and measurement methodologies.

  15. High-resolution interferometric radar images of equatorial spread F scattering structures using Capon's method

    NASA Astrophysics Data System (ADS)

    Zewdie, G. K.; Rodrigues, F. S.; Paula, E. R.

    2015-12-01

    Coherent backscatter radar imaging techniques use measurements made by multiple antenna baselines (visibility estimates) to infer the spatial distribution of the scatterers (brightness function) responsible for the observed echoes. It has been proposed that the Capon method for spectral estimation can be used for high-resolution estimation of the brightness distribution. We investigate the application of the Capon method to measurements made by a small (7-baseline) 30 MHz ionospheric coherent backscatter radar interferometer in Sao Luis, Brazil. The longest baseline of the interferometer is only 15 times the wavelength of radar signal (10 m), and the ionospheric radar soundings have been made using only 4-8 kW transmitters. Nevertheless, we have been able to obtain high-resolution (kilometric scales in the zonal direction) images of scattering structures during equatorial spread F (ESF) events over a wide field of view (+/- 10 degrees off zenith). We will present numerical simulations demonstrating the performance of the technique for the Sao Luis radar setup as well as results of the Capon technique applied to actual measurements. We will discuss the behavior of the ESF scattering structures as seen in the Capon images. The high-resolution images can assist our interpretation of plasma instabilities in the equatorial ionosphere and serve to test our ability to model the behavior of ionospheric irregularities during space weather events such as those associated with ESF.

  16. Interferometric measurement of angles.

    PubMed

    Malacara, D; Harris, O

    1970-07-01

    A new interferometric device for measuring small angles or rotations with high accuracy is described. This instrument works by counting fringes formed by the rotation of a flat-parallel plate of glass illuminated with a collimated beam from a gas laser. Some possible applications are given.

  17. Interferometric dynamic measurement: techniques based on high-speed imaging or a single photodetector.

    PubMed

    Fu, Yu; Pedrini, Giancarlo; Li, Xide

    2014-01-01

    In recent years, optical interferometry-based techniques have been widely used to perform noncontact measurement of dynamic deformation in different industrial areas. In these applications, various physical quantities need to be measured in any instant and the Nyquist sampling theorem has to be satisfied along the time axis on each measurement point. Two types of techniques were developed for such measurements: one is based on high-speed cameras and the other uses a single photodetector. The limitation of the measurement range along the time axis in camera-based technology is mainly due to the low capturing rate, while the photodetector-based technology can only do the measurement on a single point. In this paper, several aspects of these two technologies are discussed. For the camera-based interferometry, the discussion includes the introduction of the carrier, the processing of the recorded images, the phase extraction algorithms in various domains, and how to increase the temporal measurement range by using multiwavelength techniques. For the detector-based interferometry, the discussion mainly focuses on the single-point and multipoint laser Doppler vibrometers and their applications for measurement under extreme conditions. The results show the effort done by researchers for the improvement of the measurement capabilities using interferometry-based techniques to cover the requirements needed for the industrial applications. PMID:24963503

  18. Interferometric Dynamic Measurement: Techniques Based on High-Speed Imaging or a Single Photodetector

    PubMed Central

    Fu, Yu; Pedrini, Giancarlo

    2014-01-01

    In recent years, optical interferometry-based techniques have been widely used to perform noncontact measurement of dynamic deformation in different industrial areas. In these applications, various physical quantities need to be measured in any instant and the Nyquist sampling theorem has to be satisfied along the time axis on each measurement point. Two types of techniques were developed for such measurements: one is based on high-speed cameras and the other uses a single photodetector. The limitation of the measurement range along the time axis in camera-based technology is mainly due to the low capturing rate, while the photodetector-based technology can only do the measurement on a single point. In this paper, several aspects of these two technologies are discussed. For the camera-based interferometry, the discussion includes the introduction of the carrier, the processing of the recorded images, the phase extraction algorithms in various domains, and how to increase the temporal measurement range by using multiwavelength techniques. For the detector-based interferometry, the discussion mainly focuses on the single-point and multipoint laser Doppler vibrometers and their applications for measurement under extreme conditions. The results show the effort done by researchers for the improvement of the measurement capabilities using interferometry-based techniques to cover the requirements needed for the industrial applications. PMID:24963503

  19. Using Regional GPS Network Atmospheric Models for Mitigating Errors in Interferometric Synthetic Aperture Radar (InSAR) Images

    NASA Astrophysics Data System (ADS)

    Reuveni, Y.; Bock, Y.; Tong, X.; Moore, A. W.

    2015-12-01

    Interferometric Synthetic Aperture Radar (InSAR) measurements provide valuable information for obtaining Earth surface deformation and topography at high spatial resolution for crustal deformation studies. Similar to Global Positioning System (GPS), InSAR phase measurements are affected by the Earth's ionospheric and tropospheric layers as the electromagnetic signals significantly refract while propagating through the different layers. While electromagnetic signals propagating through the neutral atmosphere are affected primarily by the pressure, temperature, and water vapor content of atmospheric gases, the propagation through the ionosphere is mainly affected by the number of free electrons along the signal path. Here, we present the use of dense regional GPS networks for extracting tropospheric zenith delays and ionospheric Total Electron Content (TEC) maps in order to reduce the noise levels in the phase measurement of the InSAR images. The results show significant reduction in the RMS values when simultaneously combining the two corrections, both at short time periods where no surface deformation is expected, and at longer periods, where imaging of crustal deformation, such as the ground subsidence and aseismic fault creep, is enhanced.

  20. Interferometric hard x-ray phase contrast imaging at 204 nm grating period

    SciTech Connect

    Wen Han; Gomella, Andrew A.; Miao, Houxun; Lynch, Susanna K.; Wolfe, Douglas E.; Xiao Xianghui; Liu Chian; Morgan, Nicole

    2013-01-15

    We report on hard x-ray phase contrast imaging experiments using a grating interferometer of approximately 1/10th the grating period achieved in previous studies. We designed the gratings as a staircase array of multilayer stacks which are fabricated in a single thin film deposition process. We performed the experiments at 19 keV x-ray energy and 0.8 {mu}m pixel resolution. The small grating period resulted in clear separation of different diffraction orders and multiple images on the detector. A slitted beam was used to remove overlap of the images from the different diffraction orders. The phase contrast images showed detailed features as small as 10 {mu}m, and demonstrated the feasibility of high resolution x-ray phase contrast imaging with nanometer scale gratings.

  1. Imaging the bipolarity of myosin filaments with Interferometric Second Harmonic Generation microscopy

    PubMed Central

    Rivard, Maxime; Couture, Charles-André; Miri, Amir K.; Laliberté, Mathieu; Bertrand-Grenier, Antony; Mongeau, Luc; Légaré, François

    2013-01-01

    We report that combining interferometry with Second Harmonic Generation (SHG) microscopy provides valuable information about the relative orientation of noncentrosymmetric structures composing tissues. This is confirmed through the imaging of rat medial gastrocnemius muscle. The inteferometric Second Harmonic Generation (ISHG) images reveal that each side of the myosin filaments composing the A band of the sarcomere generates π phase shifted SHG signal which implies that the myosin proteins at each end of the filaments are oriented in opposite directions. This highlights the bipolar structural organization of the myosin filaments and shows that muscles can be considered as a periodically poled biological structure. PMID:24156065

  2. Active control of a balanced two-stage pendulum vibration isolation system and its application to laser interferometric gravity wave detectors

    SciTech Connect

    Veitch, P.J.; Robertson, N.A.; Cantley, C.A.; Hough, J. )

    1993-05-01

    The investigation of the servo control of the position of the bottom mass in a balanced two-stage pendulum vibration isolation system is reported. Experimental results for a simple prototype system and predictions based on a model presented in this paper are in good agreement. The application of such a system to a high-sensitivity laser interferometric gravity wave detector is discussed.

  3. High-resolution interferometric imaging of stress propagation in pediatric and adult skulls

    NASA Astrophysics Data System (ADS)

    Conerty, Michelle D.; Castracane, James; Clow, Lawrence P., Jr.; Koltai, Peter J.; Mouzakes, Jason

    1997-05-01

    Variations based on bone growth and development make stress and fracture propagation differ greatly in pediatric skulls as compared to adult skulls. Differentiating the stress propagation between the pediatric and adult skulls can improve diagnostic prediction when presented with direct frontal impact on a pediatric skull, a fairly common occurrence in the clinical environment. Critical diagnostic information can be learned from an in depth study of stress propagation as a function of impact force at critical locations on the periorbital region of the human skull. The Division of Pediatric Otolaryngology at Albany Medical College and InterScience, Inc. are utilizing electronic speckle pattern interferometry detection (ESPI) and high resolution imaging to evaluate and compare stress propagation in pediatric and adult skulls. A dual detection ESPI system was developed which integrates a medium resolution (2/3') CCD capable of real-time image processing, with a high resolution, megapixel detector capable of limited real time acquisition and image processing in software. Options to allow for high speed detection include integrating a custom, high performance image intensifier with the megapixel detector leg to be used as a high speed gate. The dual optical layout will allow for continuous and pulsed ESPI evaluation of calibrated impacts at specific landmarks on the skull. The goal of this work is to produce a full quantitative analysis of the stress propagation in pediatric versus adult skulls for a better understanding of bone dynamics. The work presented below concentrates on the development of the dual detection ESPI system and initial results achieved with an adult cadaver skull.

  4. Wide-field wide-band Interferometric Imaging: The WB A-Projection and Hybrid Algorithms

    NASA Astrophysics Data System (ADS)

    Bhatnagar, S.; Rau, U.; Golap, K.

    2013-06-01

    Variations of the antenna primary beam (PB) pattern as a function of time, frequency, and polarization form one of the dominant direction-dependent effects at most radio frequency bands. These gains may also vary from antenna to antenna. The A-Projection algorithm, published earlier, accounts for the effects of the narrow-band antenna PB in full polarization. In this paper, we present the wide-band A-Projection algorithm (WB A-Projection) to include the effects of wide bandwidth in the A-term itself and show that the resulting algorithm simultaneously corrects for the time, frequency, and polarization dependence of the PB. We discuss the combination of the WB A-Projection and the multi-term multi-frequency synthesis (MT-MFS) algorithm for simultaneous mapping of the sky brightness distribution and the spectral index distribution across a wide field of view. We also discuss the use of the narrow-band A-Projection algorithm in hybrid imaging schemes that account for the frequency dependence of the PB in the image domain.

  5. Alignment of a multilayer-coated imaging system using extreme ultraviolet Foucault and Ronchi interferometric testing

    SciTech Connect

    Ray-Chaudhuri, A.K.; Ng, W.; Cerrina, F.; Tan, Z.; Bjorkholm, J.; Tennant, D.; Spector, S.J.

    1995-11-01

    Multilayer-coated imaging systems for extreme ultraviolet (EUV) lithography at 13 nm represent a significant challenge for alignment and characterization. The standard practice of utilizing visible light interferometry fundamentally provides an incomplete picture since this technique fails to account for phase effects induced by the multilayer coating. Thus the development of optical techniques at the functional EUV wavelength is required. We present the development of two EUV optical tests based on Foucault and Ronchi techniques. These relatively simple techniques are extremely sensitive due to the factor of 50 reduction in wavelength. Both techniques were utilized to align a Mo--Si multilayer-coated Schwarzschild camera. By varying the illumination wavelength, phase shift effects due to the interplay of multilayer coating and incident angle were uniquely detected. {copyright} {ital 1995} {ital American} {ital Vacuum} {ital Society}

  6. Application of the interferometric synthetic aperture radar (IFSAR) correlation file for use in feature extraction

    NASA Astrophysics Data System (ADS)

    Simental, Edmundo; Guthrie, Verner

    2002-11-01

    Fine resolution synthetic aperture radar (SAR) and interferometric synthetic aperture radar (IFSAR) have been widely used for the purpose of creating viable terrain maps. A map is only as good as the information it contains. Therefore, it is a major priority of the mapmakers that the data that goes into the process be as complete and accurate as possible. In this paper, we analyze IFSAR correlation/de-correlation data to help in terrain feature information. The correlation data contains the correlation coefficient between the bottom and top IFSAR radar channels. It is a 32-bit floating-point number. This number is a measure of the absolute complex correlation coefficient between the signals that are received in each channel. The range of these numbers in between zero and unity. Unity indicates 100% correlation and zero indicates no correlation. The correlation is a function of several system parameters including signal-to-noise ratio (SNR), local geometry, and scattering mechanism. These two radar channels are physically close together and signals are inherently highly correlated. Significant difference is found beyond the fourth decimal place. We have concentrated our analysis on small features that are easily detectable in the correlation/de-correlation data and not so easily detectable in the elevation or magnitude data.

  7. Study of a passive companion microsatellite to the SAOCOM-1B satellite of Argentina, for bistatic and interferometric SAR applications

    NASA Astrophysics Data System (ADS)

    Barbier, Christian; Derauw, Dominique; Orban, Anne; Davidson, Malcolm W. J.

    2014-10-01

    We report the results of a preparatory study aimed at exploring candidate applications that could benefit from a passive micro-satellite accompanying the L-band SAOCOM-1B satellite of Argentina, and to carry out a limited demonstration, based on data acquired during ESA airborne campaigns, of selected applications. In a first step of the study, the potential applications were identified and prioritized based on the mission context and strategic applications, scientific need, and feasibility. The next step of the study was to carry out some demonstrations using data sets acquired during the BioSAR 2007-2009, TropiSAR 2009 and IceSAR 2007 campaigns. A P-band InSAR digital elevation model was generated from BioSAR 2007 data. Time-series of interferometric coherence maps were obtained as a tool for change detection and monitoring. PolInSAR processing was carried out on BioSAR 2007 and IceSAR data.

  8. Applications of Radar Interferometric Techniques to Assess Natural Hazards and their Controlling Factors

    NASA Astrophysics Data System (ADS)

    Sultan, M.; Becker, R.; Gebremichael, E.; Othman, A.; Emil, M.; Ahmed, M.; Elkadiri, R.; Pankratz, H. G.; Chouinard, K.

    2015-12-01

    Radar interferometric techniques including Persistent Scatterer (PS), Small BAseline Subset (SBAS), and two and three pass (differential interferometry) methods were applied to Synthetic Aperture Radar (SAR) datasets. These include the European Space Agency (ESA) ERS-1, ERS-2, Environmental satellite (Envisat), and Phased Array type L-band Synthetic Aperture Radar (PALSAR) to conduct the following: (1) map the spatial distribution of land deformation associated with a wide range of geologic settings, (2) quantify the rates of the observed land deformation, and (3) identify the factors controlling the observed deformation. The research topics/areas include: (1) subsidence associated with sediment compaction in a Delta setting (Nile Delta, Egypt), (2) deformation in a rifting setting (Red Sea rifting along the Red Sea coastal zone and proximal basement outcrops in Egypt and Saudi Arabia), (3) deformation associated with salt dome intrusion and the dissolution of sabkha deposits (Jazan area in Saudi Arabia), (4) mass transport associated with debris flows (Jazan area in Saudi Arabia), and (5) deformation preceding, contemporaneous with, or following large earthquakes (in Nepal; magnitude: 7.8; date: April, 25, 2015) and medium earthquakes (in Harrat Lunayyir volcanic field, central Saudi Arabia; magnitude: 5.7; date: May 19, 2009). The identification of the factor(s) controlling the observed deformation was attained through spatial correlation of extracted radar velocities with relevant temporal and static ground based and remotely sensed geological and cultural data sets (e.g., lithology, structure, precipitation, land use, and earthquake location, magnitude, and focal mechanism) in a Geographical Information System (GIS) environment.

  9. Nonlinear interferometric vibrational imaging

    NASA Technical Reports Server (NTRS)

    Boppart, Stephen A. (Inventor); Marks, Daniel L. (Inventor)

    2009-01-01

    A method of examining a sample, which includes: exposing a reference to a first set of electromagnetic radiation, to form a second set of electromagnetic radiation scattered from the reference; exposing a sample to a third set of electromagnetic radiation to form a fourth set of electromagnetic radiation scattered from the sample; and interfering the second set of electromagnetic radiation and the fourth set of electromagnetic radiation. The first set and the third set of electromagnetic radiation are generated from a source; at least a portion of the second set of electromagnetic radiation is of a frequency different from that of the first set of electromagnetic radiation; and at least a portion of the fourth set of electromagnetic radiation is of a frequency different from that of the third set of electromagnetic radiation.

  10. Performance modeling of a passive interferometric millimeter-wave sensor

    NASA Astrophysics Data System (ADS)

    Jacobs, Eddie L.; Furxhi, Orges

    2009-05-01

    This paper describes the modeling of human task performance using a passive interferometric millimeter wave (MMW) imaging sensor. The model is based on a previous model developed for concealed weapon identification using an active terahertz imager. Both models leverage the task performance modeling approach developed by the US Army Night Vision and Electronic Sensors Directorate. Key developments for this model include modeling of the effects of an interferometric antenna array, including sparse arrays, and a novel optical upconversion and processing stage being developed by the University of Delaware. Sparse interferometric arrays do not fully sample the spatial frequency extent of the image and as a result, can have degraded spatial frequency response over a fully populated array. The spatial frequency response of the sparse array can have a dramatic effect on image quality. Image quality is empirically related to task performance through the use of perception experiments. Possible applications of this model include system trade studies, concealed weapon identification, and navigation in fog and brown out conditions.

  11. Techniques and Tools for Estimating Ionospheric Effects in Interferometric and Polarimetric SAR Data

    NASA Technical Reports Server (NTRS)

    Rosen, P.; Lavalle, M.; Pi, X.; Buckley, S.; Szeliga, W.; Zebker, H.; Gurrola, E.

    2011-01-01

    The InSAR Scientific Computing Environment (ISCE) is a flexible, extensible software tool designed for the end-to-end processing and analysis of synthetic aperture radar data. ISCE inherits the core of the ROI_PAC interferometric tool, but contains improvements at all levels of the radar processing chain, including a modular and extensible architecture, new focusing approach, better geocoding of the data, handling of multi-polarization data, radiometric calibration, and estimation and correction of ionospheric effects. In this paper we describe the characteristics of ISCE with emphasis on the ionospheric modules. To detect ionospheric anomalies, ISCE implements the Faraday rotation method using quadpolarimetric images, and the split-spectrum technique using interferometric single-, dual- and quad-polarimetric images. The ability to generate co-registered time series of quad-polarimetric images makes ISCE also an ideal tool to be used for polarimetric-interferometric radar applications.

  12. Hyperspectral image projector applications

    NASA Astrophysics Data System (ADS)

    Rice, Joseph P.; Brown, Steven W.; Allen, David W.; Yoon, Howard W.; Litorja, Maritoni; Hwang, Jeeseong C.

    2012-03-01

    For the past several years NIST has been developing, along with several collaborators, a Hyperspectral Image Projector (HIP). This scene projector produces high-resolution programmable spectra and projects them into dynamic two-dimensional images. The current digital micromirror device (DMD) based HIP prototype has a spatial resolution of 1024 x 768 pixels and a spectral range of 450 nm to 2400 nm, with spectral resolution from 2 nm in the visible to 5 nm in the short-wave infrared. It disperses light from a supercontinuum fiber source across two DMDs to produce the programmable spectra, which then globally-illuminate a third DMD to form the spatial images. The HIP can simulate top-of-the atmosphere spectral radiance over a 10 mm x 14 mm, f/3 image, and this can be collimated to stimulate remote sensing instruments. Also, the spectral radiance of the projected scenes can be measured with a NIST-calibrated spectroradiometer, such that the spectral radiance projected into each pixel can be accurately known. The HIP was originally developed for applications in multi-spectral and hyperspectral imager testing, calibration, and performance validation, and examples of this application will be reviewed. Conceivable applications for the HIP in photovoltaic device characterization and optical medical imaging will also be discussed.

  13. Performance analysis of fiber optic concrete stress sensors in polarimetric and white-light interferometric configurations applicable to nuclear facilities

    NASA Astrophysics Data System (ADS)

    Bock, Wojtek J.; Urbanczyk, Waclaw; Voet, Marc R. H.

    1994-12-01

    In this paper we discuss two particular topologies of fiber-optic sensors developed recently at the Laboratory of Optoelectronics at UQAH, based on pressure induced birefringence effects occurring in HB fibers, and both in temperature-compensating configurations. We present a thorough analysis of the performance of our first industrial prototype of fiber-optic stress cell developed around the concept of polarimetric pressure sensor. This prototype is based on all- fiber configuration and uses a Corning highly birefringent fiber for sensing, for temperature compensation and for transmission of light signal; a 3M polarizing fiber is also employed as a distributed polarizer. The leading input and output HB fibers are connectorized to the semiconductor laser diode and to the portable electronic detection unit. Metrological data presented in this paper show an overall accuracy of the system better than 1% of full scale in the pressure range up to 21 MPa, including stability, repeatability and temperature drift in the range of about 35 degree(s)C. Both pressure hysteresis effects and sensitivity of the leading fibers to external perturbations are negligible, and the excellent power budget of the sensor allows for remote operation up to several kilometers. The paper presents also a novel configuration of the white-light interferometric pressure sensor based entirely on HB fibers and employing electronic scanning to improve mechanical stability of the receiving interferometer, where the white-light interference pattern registered by the CCD detector is transversally shifted with pressure. We present metrological evaluation of the laboratory prototype of this sensor for the pressures up to 40 MPa for the temperatures from 10 to 35 deg. C. We also evaluate the application of coherence multiplexing for networking this type of sensors.

  14. Application of Polarimetric-Interferometric Phase Coherence Optimization (PIPCO) Procedure to SIR-C/X-SAR Tien-Shan Tracks 122.20(94 Oct. 08)/154.20(94 Oct. 09) Repeat-Orbit C/L-Band Pol-D-InSAR Imag

    NASA Technical Reports Server (NTRS)

    Boerner, W. M.; Mott, H.; Verdi, J.; Darizhapov, D.; Dorjiev, B.; Tsybjito, T.; Korsunov, V.; Tatchkov, G.; Bashkuyev, Y.; Cloude, S.; Papathanassiou, K.; Pottier, E.; Lee, J.; Ainsworth, T.; Schuler, D.; Grandi, G.; Rosen, P.; Peltzer, G.

    1998-01-01

    During the past decade, Radar Polarimetry has established itself as a mature science and advanced technology in high resolution POL-SAR imaging, image target characterization and selective image feature extraction.

  15. Combined optical micromanipulation and interferometric topography (COMMIT).

    PubMed

    Sarshar, Mohammad; Lu, Thompson; Anvari, Bahman

    2016-04-01

    Optical tweezers have emerged as a prominent light-based tool for pico-Newton (pN) force microscopy in mechanobiological studies. However, the efficacy of optical tweezers are limited in applications where concurrent metrology of the nano-sized structures under interrogation is essential to the quantitative analysis of its mechanical properties and various mechanotransduction events. We have developed an all-optical platform delivering pN force resolution in parallel with nano-scale structural imaging of the biological sample by combining optical tweezers with interferometric quantitative phase microscopy. These capabilities allow real-time micromanipulation and label-free measurement of sample's nanostructures and nanomechanical responses, opening avenues to a wide range of new research possibilities and applications in biology. PMID:27446661

  16. Combined optical micromanipulation and interferometric topography (COMMIT)

    PubMed Central

    Sarshar, Mohammad; Lu, Thompson; Anvari, Bahman

    2016-01-01

    Optical tweezers have emerged as a prominent light-based tool for pico-Newton (pN) force microscopy in mechanobiological studies. However, the efficacy of optical tweezers are limited in applications where concurrent metrology of the nano-sized structures under interrogation is essential to the quantitative analysis of its mechanical properties and various mechanotransduction events. We have developed an all-optical platform delivering pN force resolution in parallel with nano-scale structural imaging of the biological sample by combining optical tweezers with interferometric quantitative phase microscopy. These capabilities allow real-time micromanipulation and label-free measurement of sample’s nanostructures and nanomechanical responses, opening avenues to a wide range of new research possibilities and applications in biology. PMID:27446661

  17. Interferometric phase-contrast X-ray CT imaging of VX2 rabbit cancer at 35keV X-ray energy

    NASA Astrophysics Data System (ADS)

    Takeda, Tohoru; Wu, Jin; Tsuchiya, Yoshinori; Yoneyama, Akio; Lwin, Thet-Thet; Hyodo, Kazuyuki; Itai, Yuji

    2004-05-01

    Imaging of large objects at 17.7-keV low x-ray energy causes huge x-ray exposure to the objects even using interferometric phase-contrast x-ray CT (PCCT). Thus, we tried to obtain PCCT images at high x-ray energy of 35keV and examined the image quality using a formalin-fixed VX2 rabbit cancer specimen with 15-mm in diameter. The PCCT system consisted of an asymmetrically cut silicon (220) crystal, a monolithic x-ray interferometer, a phase-shifter, an object cell and an x-ray CCD camera. The PCCT at 35 keV clearly visualized various inner structures of VX2 rabbit cancer such as necrosis, cancer, the surrounding tumor vessels, and normal liver tissue. Besides, image-contrast was not degraded significantly. These results suggest that the PCCT at 35 KeV is sufficient to clearly depict the histopathological morphology of VX2 rabbit cancer specimen.

  18. High Temperature Millimeter Wave Radiometric and Interferometric Measurements of Slag-Refractory Interaction for Application to Coal Gasifiers

    NASA Astrophysics Data System (ADS)

    McCloy, John S.; Crum, Jarrod V.; Sundaram, S. K.; Slaugh, Ryan; Woskov, Paul P.

    2011-11-01

    Millimeter wave (MMW) radiometry can be used for simultaneous measurement of emissivity and temperature of materials under extreme environments such as in slagging coal gasifiers, where sensors have been identified as a key enabling technology need for process optimization. We present a dual-channel MMW heterodyne radiometer with active interferometric capability that allows simultaneous measurements of sample temperature, emissivity, and flow dynamics. Interferometric capability at 137 GHz is supplied via a probe signal originating from a local oscillator allowing monitoring of sample dynamics such as volume expansion and thickness change. This capability has been used to monitor characteristic behavior between refractories and slag such as slag infiltration, slag melting, viscous flow, foaming, and crucible corrosion by the molten slag. These results show the promise of the MMW system for extracting process parameters from operating slagging coal gasifiers, providing valuable information for process efficiency, control, and increased productivity.

  19. High temperature millimeter wave radiometric and interferometric measurements of slag-refractory interaction for application to coal gasifiers

    SciTech Connect

    McCloy, John S.; Crum, Jarrod V.; Sundaram, S. K.; Slaugh, Ryan W.; Woskov, Paul P.

    2011-09-17

    Millimeter wave (MMW) radiometry can be used for simultaneous measurement of emissivity and temperature of materials under extreme environments (high temperature, pressure, and corrosive environments) such as in slagging coal gasifiers, where sensors have been identified as a key enabling technology need for process optimization. We present a state-of-the-art dual-channel MMW heterodyne radiometer with active interferometric capability that allows simultaneous radiometric measurements of sample temperature, emissivity, and flow dynamics to over 1873 K. Interferometric capability is supplied via a probe signal originating from the 137 GHz radiometer local oscillator (LO). The interferometric 'video' channels allow measurement of additional parameters simultaneously, such as volume expansion, thickness change, and slag viscosity along with temperature or emissivity. This capability has been used to demonstrate measurement of temperature and simulated coal slag infiltration into a chromia refractory brick sample as well as slag flow down a vertically placed refractory brick. Observed phenomena include slag melting and slumping, slag reboil and foam with oxygen evolution, and eventual failure of the alumina crucible through corrosion by the molten slag. These results show the promise of the MMW system for extracting quantitative and qualitative process parameters from operating slagging coal gasifiers, providing valuable information for process efficiency, control, and increased productivity.

  20. Monomode Fibre Optic Interferometric Sensors.

    NASA Astrophysics Data System (ADS)

    Leilabady, P. Akhavan

    Available from UMI in association with The British Library. Optical fibre sensors are playing an increasingly important role in industrial, medical and military application. Not only are conventional electrically based sensors being gradually replaced by their fibre optic analogues, but also fibre optic sensors are being deployed in special applications where electrically based sensors are unsuitable. Their immunity to electromagnetic interference and inherent high measurement resolution give optical fibre sensors an advantage in diverse applications, including the aerospace and power generation industry and in medicine. The theme of this thesis is interferometric techniques for the recovery of measurand induced modulations of the the fibre guided optical beam. Interferometry offers high measurement resolutions, which makes it the preferred choice for optical processing in certain sensor systems. Interferometric techniques developed for the recovery of the optical phase, polarisation ellipticity and polarisation azimuth are described. However, there are a number of problems, such as the very limited operating range and long term stability that hinder practical implementation of interferometric sensors. These problems are addressed and novel optical processing circuitry based on interferometric detection of phase and polarisation state are introduced which facilitates the development of practical all fibre sensors. Our discussions will start by a general overview of the fibre optic sensor technology, Chapter 1, introducing the principle of sensing by light and the three major categories of fibre optic sensors; multimode fibre intensity modulated sensors, monomode fibre phase modulated sensors and birefringent fibre polarisation state modulated sensors. In Chapter 3, the category of sensors based on phase modulation is addressed describing research carried out into developing an all-fibre optic vortex shedding flowmeter, illustrating interferometric techniques for

  1. Interferometric Plasmonic Lensing with Nanohole Arrays

    SciTech Connect

    Gong, Yu; Joly, Alan G.; El-Khoury, Patrick Z.; Hess, Wayne P.

    2014-12-18

    Nonlinear photoemission electron microscopy (PEEM) of nanohole arrays in gold films maps propagating surface plasmons (PSPs) launched from lithographically patterned structures. Strong near field photoemission patterns are observed in the PEEM images, recorded following low angle of incidence irradiation of nanohole arrays with sub-15 fs laser pulses centered at 780 nm. The recorded photoemission patterns are attributed to constructive and destructive interferences between PSPs launched from the individual nanoholes which comprise the array. By exploiting the wave nature of PSPs, we demonstrate how varying the array geometry (hole diameter, pitch, and number of rows/columns) ultimately yields intense localized photoemission. Through a combination of PEEM and finite-difference time-domain simulations, we identify the optimal array geometry for efficient light coupling and interferometric plasmonic lensing. We show a preliminary application of inteferometric plasmonic lensing by enhancing the photoemission from the vertex of a gold triangle using nanohole array.

  2. Imaging and chemical surface analysis of biomolecular functionalization of monolithically integrated on silicon Mach-Zehnder interferometric immunosensors

    NASA Astrophysics Data System (ADS)

    Gajos, Katarzyna; Angelopoulou, Michailia; Petrou, Panagiota; Awsiuk, Kamil; Kakabakos, Sotirios; Haasnoot, Willem; Bernasik, Andrzej; Rysz, Jakub; Marzec, Mateusz M.; Misiakos, Konstantinos; Raptis, Ioannis; Budkowski, Andrzej

    2016-11-01

    Time-of-flight secondary ion mass spectrometry (imaging, micro-analysis) has been employed to evaluate biofunctionalization of the sensing arm areas of Mach-Zehnder interferometers monolithically integrated on silicon chips for the immunochemical (competitive) detection of bovine κ-casein in goat milk. Biosensor surfaces are examined after: modification with (3-aminopropyl)triethoxysilane, application of multiple overlapping spots of κ-casein solutions, blocking with 100-times diluted goat milk, and reaction with monoclonal mouse anti-κ-casein antibodies in blocking solution. The areas spotted with κ-casein solutions of different concentrations are examined and optimum concentration providing homogeneous coverage is determined. Coverage of biosensor surfaces with biomolecules after each of the sequential steps employed in immunodetection is also evaluated with TOF-SIMS, supplemented by Atomic force microscopy and X-ray photoelectron spectroscopy. Uniform molecular distributions are observed on the sensing arm areas after spotting with optimum κ-casein concentration, blocking and immunoreaction. The corresponding biomolecular compositions are determined with a Principal Component Analysis that distinguished between protein amino acids and milk glycerides, as well as between amino acids characteristic for Mabs and κ-casein, respectively. Use of the optimum conditions (κ-casein concentration) for functionalization of chips with arrays of ten Mach-Zehnder interferometers provided on-chips assays with dramatically improved both intra-chip response repeatability and assay detection sensitivity.

  3. An Automated Mapping Processor using C-Band Interferometric SAR Data

    NASA Technical Reports Server (NTRS)

    Rodriguez, E.; Michel, T. R.; Martin, J. M.; Houshmand, B.

    1996-01-01

    We describe a processor which has been implemented to generate map products starting from C-band interferometric data. The first stage of the processor consists of the conventional interferometric synthetic aperture radar (SAR) processing producing a digital elevation model (DEM) and a SAR brightness image in sensor coordinates. In the second stage of processing, a land use classification map is obtained by using the DEM, brightness, and interferometric correlation layers. Auxiliary layers which include a drainage layer, a height gradient layer, a height error layer, an estimated penetration layer, and a shaded relief layer are also computed. In the final step, all UTM collocated layers are combined in a geographical information system (GIS) which allows for both hard copy map products and digital applications.

  4. An Automated Mapping Processor Using C-Band Interferometric SAR Data

    NASA Technical Reports Server (NTRS)

    Rodriguez, E.; Michel, T. R.; Martin, J. M.; Houshmand, B.

    1996-01-01

    We present the description of a processor which has been implemented to generate map products starting from C-band interferometric data. The first stage of the processor consists of the conventional interferometric SAR processing producing a Digital Elevation Model (DEMs) and a SAR brightness image in sensor coordinates. In the second stage of processing, a land use classification map is obtained by using the DEM, brightness, and interferometric correlation layers. Auxiliary layers which include a drainage layer, a height gradient layer, a height error layer, an estimated penetration layer, and a shaded relief layer are also computed. In the final step, all UTM collocated layers are combined in a GIS system which allows for both hard copy map products and for digital applications.

  5. Foliage problem in interferometric SAR

    NASA Astrophysics Data System (ADS)

    Rogers, George W.; Mansfield, Arthur W.; Roth, Duane; Poehler, Paul L.; Rais, Houra

    1999-08-01

    Interferometric SAR exploits the coherent nature of multiple synthetic aperture radar images to recover phase (range difference) information and thence terrain evaluation data as well as other phase derivative products such as Coherent Change Detection (CCD). Of the numerous factors that can degrade the coherency of multiple SAR collections, foliage constitutes one of the most challenging. The foliage problem in IFSAR is discussed and an airborne multiple pass collection is used to illustrate some facets of the problem. Resolution as a variable in the tradeoff between the bias and variance of the interferogram is discussed in the context of the example.

  6. Identifying and discriminating phase transitions along decaying shocks with line imaging Doppler interferometric velocimetry and streaked optical pyrometry

    NASA Astrophysics Data System (ADS)

    Millot, Marius

    2016-01-01

    Ultrafast line-imaging velocity interferometer system for any reflector and streaked optical pyrometry are now commonly used to obtain high precision equation of state and electronic transport data under dynamic compression at major high energy density science facilities. We describe a simple way to improve distinguishing phase transformation signatures from other signals when monitoring decaying shock waves. The line-imaging capability of these optical diagnostics offers additional supporting evidence to the assignment of particular anomalies—such as plateaus or reversals—to the occurrence of a phase transition along the Hugoniot. We illustrate the discussion with two example datasets collected during laser driven shock compression of quartz and stishovite.

  7. A methodology for outperforming filtering results in the interferometric process

    NASA Astrophysics Data System (ADS)

    Saqellari-Likoka, A.; Karathanassi, V.

    2015-10-01

    In this study, a method for reducing the filtering effects on the interferometric phase signal is proposed. Theoretical analysis showed that while noise reduction is maximized after filtering, the loose of interferometric phase signal is also maximized. This state has been also verified by observations on SAR interferometric data where pixels with high coherence value, which are assumed to contain a lot of information, presented lower coherence values after SAR image filtering. The proposed method performs interferometric phase modeling. The method recovers the signal after the interferometric filtering for the pixels that loss of information is observed. The selection of these pixels is based on the decrease of their coherence value after the filtering. Signal recovery is associated to the preservation of the initial values for these pixels. Consequently, the method prevents the decrease of the coherence values for these pixels. Performance of the method depends on the performance of the used filter; however, it always improves the interferometric results. Since the phase signal is the basis for the DEM production, its preservation improves all the steps of the interferometric procedure, especially the phase unwapping. Effects of the method on the final interferometric product, the DEM, are also evident. The proposed method was evaluated using real interferometric data. Experiments showed that the applied filters within this study, did not always improve the accuracy of the produced DEM. Sub-images for which filtering does not improve their mean coherence value have been selected and the proposed method has been applied. For these sub-images, coherence values and RMS errors of the produced DEMs showed that the method improves the results of the interferometric procedure. It compensates the negative effects of the filtering for these sub-images and leads to the improvement of the DEM accuracy in the majority of the cases.

  8. Robust high-contrast companion detection from interferometric observations. The CANDID algorithm and an application to six binary Cepheids

    NASA Astrophysics Data System (ADS)

    Gallenne, A.; Mérand, A.; Kervella, P.; Monnier, J. D.; Schaefer, G. H.; Baron, F.; Breitfelder, J.; Le Bouquin, J. B.; Roettenbacher, R. M.; Gieren, W.; Pietrzyński, G.; McAlister, H.; ten Brummelaar, T.; Sturmann, J.; Sturmann, L.; Turner, N.; Ridgway, S.; Kraus, S.

    2015-07-01

    Context. Long-baseline interferometry is an important technique to spatially resolve binary or multiple systems in close orbits. By combining several telescopes together and spectrally dispersing the light, it is possible to detect faint components around bright stars in a few hours of observations. Aims: We provide a rigorous and detailed method to search for high-contrast companions around stars, determine the detection level, and estimate the dynamic range from interferometric observations. Methods: We developed the code CANDID (Companion Analysis and Non-Detection in Interferometric Data), a set of Python tools that allows us to search systematically for point-source, high-contrast companions and estimate the detection limit using all interferometric observables, i.e., the squared visibilities, closure phases and bispectrum amplitudes. The search procedure is made on a N × N grid of fit, whose minimum needed resolution is estimated a posteriori. It includes a tool to estimate the detection level of the companion in the number of sigmas. The code CANDID also incorporates a robust method to set a 3σ detection limit on the flux ratio, which is based on an analytical injection of a fake companion at each point in the grid. Our injection method also allows us to analytically remove a detected component to 1) search for a second companion; and 2) set an unbiased detection limit. Results: We used CANDID to search for the companions around the binary Cepheids V1334 Cyg, AX Cir, RT Aur, AW Per, SU Cas, and T Vul. First, we showed that our previous discoveries of the components orbiting V1334 Cyg and AX Cir were detected at >25σ and >13σ, respectively. The astrometric positions and flux ratios provided by CANDID for these two stars are in good agreement with our previously published values. The companion around AW Per is detected at more than 15σ with a flux ratio of f = 1.22 ± 0.30%, and it is located at ρ = 32.16 ± 0.29 mas and PA = 67.1 ± 0.3°. We made a

  9. Applications of Molecular Imaging

    PubMed Central

    Galbán, Craig; Galbán, Stefanie; Van Dort, Marcian; Luker, Gary D.; Bhojani, Mahaveer S.; Rehemtualla, Alnawaz; Ross, Brian D.

    2015-01-01

    Today molecular imaging technologies play a central role in clinical oncology. The use of imaging techniques in early cancer detection, treatment response and new therapy development is steadily growing and has already significantly impacted clinical management of cancer. In this chapter we will overview three different molecular imaging technologies used for the understanding of disease biomarkers, drug development, or monitoring therapeutic outcome. They are (1) optical imaging (bioluminescence and fluorescence imaging) (2) magnetic resonance imaging (MRI), and (3) nuclear imaging (e.g, single photon emission computed tomography (SPECT) and positron emission tomography (PET)). We will review the use of molecular reporters of biological processes (e.g. apoptosis and protein kinase activity) for high throughput drug screening and new cancer therapies, diffusion MRI as a biomarker for early treatment response and PET and SPECT radioligands in oncology. PMID:21075334

  10. Interferometric SAR coherence classification utility assessment

    SciTech Connect

    Yocky, D.A.

    1998-03-01

    The classification utility of a dual-antenna interferometric synthetic aperture radar (IFSAR) is explored by comparison of maximum likelihood classification results for synthetic aperture radar (SAR) intensity images and IPSAR intensity and coherence images. The addition of IFSAR coherence improves the overall classification accuracy for classes of trees, water, and fields. A threshold intensity-coherence classifier is also compared to the intensity-only classification results.

  11. High-accuracy simultaneous measurement of particle size and location using interferometric out-of-focus imaging.

    PubMed

    Qieni, Lu; Kan, Han; Baozhen, Ge; Xiang, Wang

    2016-07-25

    A method based on unidirectional gradient-matched algorithm and Fourier transform technique is proposed to simultaneously extract the location and the number of fringes/fringe spacing of a particle interferogram. The position coordinate (x,y) of a particle can be determined with high accuracy because of the elimination of the fringe within the particle fringe pattern. Furthermore, the method can be employed to achieve sub-pixel frequency extraction when combined with an improved Rife algorithm. The performance of the method has been verified by numerical simulations and experimental measurements. The results suggest that the method presented here is highly beneficial to applications such as spray, in accurately measuring both the particle size and its location. PMID:27464108

  12. Real applications of quantum imaging

    NASA Astrophysics Data System (ADS)

    Genovese, Marco

    2016-07-01

    In previous years the possibility of creating and manipulating quantum states of light has paved the way for the development of new technologies exploiting peculiar properties of quantum states, such as quantum information, quantum metrology and sensing, quantum imaging, etc. In particular quantum imaging addresses the possibility of overcoming limits of classical optics by using quantum resources such as entanglement or sub-Poissonian statistics. Albeit, quantum imaging is a more recent field than other quantum technologies, e.g. quantum information, it is now mature enough for application. Several different protocols have been proposed, some of them only theoretically, others with an experimental implementation and a few of them pointing to a clear application. Here we present a few of the most mature protocols ranging from ghost imaging to sub shot noise imaging and sub-Rayleigh imaging.

  13. The Fringe-Imaging Skin Friction Technique PC Application User's Manual

    NASA Technical Reports Server (NTRS)

    Zilliac, Gregory G.

    1999-01-01

    A personal computer application (CXWIN4G) has been written which greatly simplifies the task of extracting skin friction measurements from interferograms of oil flows on the surface of wind tunnel models. Images are first calibrated, using a novel approach to one-camera photogrammetry, to obtain accurate spatial information on surfaces with curvature. As part of the image calibration process, an auxiliary file containing the wind tunnel model geometry is used in conjunction with a two-dimensional direct linear transformation to relate the image plane to the physical (model) coordinates. The application then applies a nonlinear regression model to accurately determine the fringe spacing from interferometric intensity records as required by the Fringe Imaging Skin Friction (FISF) technique. The skin friction is found through application of a simple expression that makes use of lubrication theory to relate fringe spacing to skin friction.

  14. Multi-colour microscopic interferometry for optical metrology and imaging applications

    NASA Astrophysics Data System (ADS)

    Upputuri, Paul Kumar; Pramanik, Manojit; Nandigana, Krishna Mohan; Kothiyal, Mahendra Prasad

    2016-09-01

    Interferometry has been widely used for optical metrology and imaging applications because of their precision, reliability, and versatility. Although single-wavelength interferometery can provide high sensitivity and resolution, it has several drawbacks, namely, it fails to quantify large-discontinuities, large-deformations, and shape of unpolished surfaces. Multiple-wavelength techniques have been successfully used to overcome the drawbacks associated with single wavelength analysis. The use of colour CCD camera allows simultaneous acquisition of multiple interferograms. The advances in colour CCD cameras and image processing techniques have made the multi-colour interferometry a faster, simpler, and cost-effective tool for industrial applications. This article reviews the recent advances in multi-colour interferometric techniques and their demanding applications for characterization of micro-systems, non-destructive testing, and bio-imaging applications.

  15. Source Detection with Interferometric Datasets

    NASA Astrophysics Data System (ADS)

    Trott, Cathryn M.; Wayth, Randall B.; Macquart, Jean-Pierre R.; Tingay, Steven J.

    2012-04-01

    The detection of sources in interferometric radio data typically relies on extracting information from images, formed by Fourier transform of the underlying visibility dataset, and CLEANed of contaminating sidelobes through iterative deconvolution. Variable and transient radio sources span a large range of variability timescales, and their study has the potential to enhance our knowledge of the dynamic universe. Their detection and classification involve large data rates and non-stationary PSFs, commensal observing programs and ambitious science goals, and will demand a paradigm shift in the deployment of next-generation instruments. Optimal source detection and classification in real time requires efficient and automated algorithms. On short time-scales variability can be probed with an optimal matched filter detector applied directly to the visibility dataset. This paper shows the design of such a detector, and some preliminary detection performance results.

  16. Detection of Fast Transients with Radio Interferometric Arrays

    NASA Astrophysics Data System (ADS)

    Bhat, N. D. R.; Chengalur, J. N.; Cox, P. J.; Gupta, Y.; Prasad, J.; Roy, J.; Bailes, M.; Burke-Spolaor, S.; Kudale, S. S.; van Straten, W.

    2013-05-01

    Next-generation radio arrays, including the Square Kilometre Array (SKA) and its pathfinders, will open up new avenues for exciting transient science at radio wavelengths. Their innovative designs, comprising a large number of small elements, pose several challenges in digital processing and optimal observing strategies. The Giant Metre-wave Radio Telescope (GMRT) presents an excellent test-bed for developing and validating suitable observing modes and strategies for transient experiments with future arrays. Here we describe the first phase of the ongoing development of a transient detection system for GMRT that is planned to eventually function in a commensal mode with other observing programs. It capitalizes on the GMRT's interferometric and sub-array capabilities, and the versatility of a new software backend. We outline considerations in the plan and design of transient exploration programs with interferometric arrays, and describe a pilot survey that was undertaken to aid in the development of algorithms and associated analysis software. This survey was conducted at 325 and 610 MHz, and covered 360 deg2 of the sky with short dwell times. It provides large volumes of real data that can be used to test the efficacies of various algorithms and observing strategies applicable for transient detection. We present examples that illustrate the methodologies of detecting short-duration transients, including the use of sub-arrays for higher resilience to spurious events of terrestrial origin, localization of candidate events via imaging, and the use of a phased array for improved signal detection and confirmation. In addition to demonstrating applications of interferometric arrays for fast transient exploration, our efforts mark important steps in the roadmap toward SKA-era science.

  17. DETECTION OF FAST TRANSIENTS WITH RADIO INTERFEROMETRIC ARRAYS

    SciTech Connect

    Bhat, N. D. R.; Chengalur, J. N.; Gupta, Y.; Prasad, J.; Roy, J.; Kudale, S. S.; Cox, P. J.; Bailes, M.; Burke-Spolaor, S.; Van Straten, W.

    2013-05-01

    Next-generation radio arrays, including the Square Kilometre Array (SKA) and its pathfinders, will open up new avenues for exciting transient science at radio wavelengths. Their innovative designs, comprising a large number of small elements, pose several challenges in digital processing and optimal observing strategies. The Giant Metre-wave Radio Telescope (GMRT) presents an excellent test-bed for developing and validating suitable observing modes and strategies for transient experiments with future arrays. Here we describe the first phase of the ongoing development of a transient detection system for GMRT that is planned to eventually function in a commensal mode with other observing programs. It capitalizes on the GMRT's interferometric and sub-array capabilities, and the versatility of a new software backend. We outline considerations in the plan and design of transient exploration programs with interferometric arrays, and describe a pilot survey that was undertaken to aid in the development of algorithms and associated analysis software. This survey was conducted at 325 and 610 MHz, and covered 360 deg{sup 2} of the sky with short dwell times. It provides large volumes of real data that can be used to test the efficacies of various algorithms and observing strategies applicable for transient detection. We present examples that illustrate the methodologies of detecting short-duration transients, including the use of sub-arrays for higher resilience to spurious events of terrestrial origin, localization of candidate events via imaging, and the use of a phased array for improved signal detection and confirmation. In addition to demonstrating applications of interferometric arrays for fast transient exploration, our efforts mark important steps in the roadmap toward SKA-era science.

  18. Fast interferometric second harmonic generation microscopy

    PubMed Central

    Bancelin, Stéphane; Couture, Charles-André; Légaré, Katherine; Pinsard, Maxime; Rivard, Maxime; Brown, Cameron; Légaré, François

    2016-01-01

    We report the implementation of fast Interferometric Second Harmonic Generation (I-SHG) microscopy to study the polarity of non-centrosymmetric structures in biological tissues. Using a sample quartz plate, we calibrate the spatially varying phase shift introduced by the laser scanning system. Compensating this phase shift allows us to retrieve the correct phase distribution in periodically poled lithium niobate, used as a model sample. Finally, we used fast interferometric second harmonic generation microscopy to acquire phase images in tendon. Our results show that the method exposed here, using a laser scanning system, allows to recover the polarity of collagen fibrils, similarly to standard I-SHG (using a sample scanning system), but with an imaging time about 40 times shorter. PMID:26977349

  19. Implementation of SAR interferometric map generation using parallel processors

    SciTech Connect

    Doren, N.; Wahl, D.E.

    1998-07-01

    Interferometric fringe maps are generated by accurately registering a pair of complex SAR images of the same scene imaged from two very similar geometries, and calculating the phase difference between the two images by averaging over a neighborhood of pixels at each spatial location. The phase difference (fringe) map resulting from this IFSAR operation is then unwrapped and used to calculate the height estimate of the imaged terrain. Although the method used to calculate interferometric fringe maps is well known, it is generally executed in a post-processing mode well after the image pairs have been collected. In that mode of operation, there is little concern about algorithm speed and the method is normally implemented on a single processor machine. This paper describes how the interferometric map generation is implemented on a distributed-memory parallel processing machine. This particular implementation is designed to operate on a 16 node Power-PC platform and to generate interferometric maps in near real-time. The implementation is able to accommodate large translational offsets, along with a slight amount of rotation which may exist between the interferometric pair of images. If the number of pixels in the IFSAR image is large enough, the implementation accomplishes nearly linear speed-up times with the addition of processors.

  20. Full-field interferometric confocal microscopy using a VCSEL array

    PubMed Central

    Redding, Brandon; Bromberg, Yaron; Choma, Michael A.; Cao, Hui

    2014-01-01

    We present an interferometric confocal microscope using an array of 1200 VCSELs coupled to a multimode fiber. Spatial coherence gating provides ~18,000 continuous virtual pinholes allowing an entire en face plane to be imaged in a snapshot. This approach maintains the same optical sectioning as a scanning confocal microscope without moving parts, while the high power of the VCSEL array (~5 mW per laser) enables high-speed image acquisition with integration times as short as 100 µs. Interferometric detection also recovers the phase of the image, enabling quantitative phase measurements and improving the contrast when imaging phase objects. PMID:25078199

  1. Multipulse interferometric frequency-resolved optical gating

    SciTech Connect

    Siders, C.W.; Siders, J.L.W.; Omenetto, F.G.; Taylor, A.J.

    1999-04-01

    The authors review multipulse interferometric frequency-resolved optical gating (MI-FROG) as a technique, uniquely suited for pump-probe coherent spectroscopy using amplified visible and near-infrared short-pulse systems and/or emissive targets, for time-resolving ultrafast phase shifts and intensity changes. Application of polarization-gate MI-FROG to the study of ultrafast ionization in gases is presented.

  2. TE/TM Simulations of Interferometric Measurements

    NASA Technical Reports Server (NTRS)

    Houshmand, Bijan

    2000-01-01

    Interferometric synthetic aperture radar (IFSAR) measurements at X-, C-, L-, and P-band are used to derive ground topography at meter level resolution. Interpretation of the derived topography requires attention due to the complex interaction of the radar signal with ground cover. The presence of penetrable surfaces such as vegetation, and tree canopies poses a challenge since the depth of penetration depends on a number of parameters such as the operating radar frequency, polarization, incident angle, as well as terrain structure. The dependence of the reconstructed topography on polarization may lead to the characterization of the ground cover. Simulation of interferometric measurements is useful for interpretation of the derived topography (B. Houshmand, Proceedings of URSI, 314, 1997). In this talk , time domain simulations for interferometric measurement for TE- and TM- polarization are presented. Time domain simulation includes the effects of the surface material property as well geometry comparable the radar signal wavelength (B. Houshmand, Proceedings of the URSI, 25, 1998). The IFSAR simulation is carried out in two steps. First, the forward scattering data is generated based on full wave analysis. Next, the electromagnetic information is inverted to generate surface topography. This inversion is based on the well known IFSAR processing technique which is composed of signal compression, and formation of an interferogram. The full wave forward scattering data is generated by the scattered-field formulation of the FDTD algorithm. The simulation is carried out by exciting the computational domain by a radar signal. The scattered field is then computed and translated to the receiving interferometric antennas using the time-domain Huygen's principle. The inversion process starts by compressing the time-domain data. The range compressed data from both receivers are then coregistered to form an interferogram. The resulting interferogram is then related to the

  3. Image wavelet decomposition and applications

    NASA Technical Reports Server (NTRS)

    Treil, N.; Mallat, S.; Bajcsy, R.

    1989-01-01

    The general problem of computer vision has been investigated for more that 20 years and is still one of the most challenging fields in artificial intelligence. Indeed, taking a look at the human visual system can give us an idea of the complexity of any solution to the problem of visual recognition. This general task can be decomposed into a whole hierarchy of problems ranging from pixel processing to high level segmentation and complex objects recognition. Contrasting an image at different representations provides useful information such as edges. An example of low level signal and image processing using the theory of wavelets is introduced which provides the basis for multiresolution representation. Like the human brain, we use a multiorientation process which detects features independently in different orientation sectors. So, images of the same orientation but of different resolutions are contrasted to gather information about an image. An interesting image representation using energy zero crossings is developed. This representation is shown to be experimentally complete and leads to some higher level applications such as edge and corner finding, which in turn provides two basic steps to image segmentation. The possibilities of feedback between different levels of processing are also discussed.

  4. Crustal-scale interferometric imaging in the Malargüe region, Argentina, with P-wave coda and multidimensional deconvolution

    NASA Astrophysics Data System (ADS)

    Nishitsuji, Yohei; Minato, Shohei; Hartstra, Iris; Boullenger, Boris; Wapenaar, Kees; Gomez, Martín; Draganov, Deyan

    2016-04-01

    Several seismic investigations - using receiver-function methods as well as tomographic approaches - have been carried out in the Malargüe region (Argentina) for various purposes over a few decades. We use a body-wave seismic interferometry (SI) approach to retrieve reflections later used for the consecutive imaging of the subsurface. We investigate the applicability of the body-wave SI using P-wave coda from local earthquakes with the aim to retrieve reflection responses from a part of the Andean crust below the seismic array we use. We called our technique local-earthquake P-wave coda (LEPC) SI. In this presentation, we show three different LEPC SI results based on three different SI theories: crosscorrelation, crosscoherence, and multidimensional deconvolution. We find that, from a structural-interpretation point of view, multidimensional deconvolution based on the truncated singular-value decomposition scheme provides us with a better structural imaging than the other SI approaches. We interpret deep thrust faults in the imaging results from LEPC SI, whose presence in this region has previously been indicated from interpretation of active seismic-survey data and exploration-well data. We also interpret dimmed-amplitude parts in the reflection image as possible melting zones that have been previously indicated by magnetotelluric methods. The LEPC SI method we propose could be used as a low-cost alternative to active-source seismic surveys for imaging and monitoring purposes of deeper geothermal reservoirs, e.g. in enhanced geothermal systems where the target structures are down to 10 km depth.

  5. Planning applications in image analysis

    NASA Technical Reports Server (NTRS)

    Boddy, Mark; White, Jim; Goldman, Robert; Short, Nick, Jr.

    1994-01-01

    We describe two interim results from an ongoing effort to automate the acquisition, analysis, archiving, and distribution of satellite earth science data. Both results are applications of Artificial Intelligence planning research to the automatic generation of processing steps for image analysis tasks. First, we have constructed a linear conditional planner (CPed), used to generate conditional processing plans. Second, we have extended an existing hierarchical planning system to make use of durations, resources, and deadlines, thus supporting the automatic generation of processing steps in time and resource-constrained environments.

  6. New approaches in interferometric SAR data processing

    NASA Technical Reports Server (NTRS)

    Lin, Qian; Vesecky, John F.; Zebker, Howard A.

    1992-01-01

    It is well established that interferometric synthetic aperture radar (SAR) images can be inverted to perform surface elevation mapping. Among the factors critical to the mapping accuracy are registration of the interfering SAR images and phase unwrapping. A novel registration algorithm is presented that determines the registration parameters through optimization. A new figure of merit is proposed that evaluates the registration result during the optimization. The phase unwrapping problem is approached through a new method involving fringe line detection. The algorithms are tested with two SEASAT SAR images of terrain near Yellowstone National Park. These images were collected on Seasat orbits 1334 and 1420, which were very close together in space, i.e., less than 100 m. The resultant elevation map is compared with the USGS digital terrain elevation model.

  7. uvmcmcfit: Parametric models to interferometric data fitter

    NASA Astrophysics Data System (ADS)

    Bussmann, Shane; Leung, Tsz Kuk (Daisy); Conley, Alexander

    2016-06-01

    Uvmcmcfit fits parametric models to interferometric data. It is ideally suited to extract the maximum amount of information from marginally resolved observations with interferometers like the Atacama Large Millimeter Array (ALMA), Submillimeter Array (SMA), and Plateau de Bure Interferometer (PdBI). uvmcmcfit uses emcee (ascl:1303.002) to do Markov Chain Monte Carlo (MCMC) and can measure the goodness of fit from visibilities rather than deconvolved images, an advantage when there is strong gravitational lensing and in other situations. uvmcmcfit includes a pure-Python adaptation of Miriad’s (ascl:1106.007) uvmodel task to generate simulated visibilities given observed visibilities and a model image and a simple ray-tracing routine that allows it to account for both strongly lensed systems (where multiple images of the lensed galaxy are detected) and weakly lensed systems (where only a single image of the lensed galaxy is detected).

  8. Electromagnetic Imaging Methods for Nondestructive Evaluation Applications

    PubMed Central

    Deng, Yiming; Liu, Xin

    2011-01-01

    Electromagnetic nondestructive tests are important and widely used within the field of nondestructive evaluation (NDE). The recent advances in sensing technology, hardware and software development dedicated to imaging and image processing, and material sciences have greatly expanded the application fields, sophisticated the systems design and made the potential of electromagnetic NDE imaging seemingly unlimited. This review provides a comprehensive summary of research works on electromagnetic imaging methods for NDE applications, followed by the summary and discussions on future directions. PMID:22247693

  9. Electromagnetic imaging methods for nondestructive evaluation applications.

    PubMed

    Deng, Yiming; Liu, Xin

    2011-01-01

    Electromagnetic nondestructive tests are important and widely used within the field of nondestructive evaluation (NDE). The recent advances in sensing technology, hardware and software development dedicated to imaging and image processing, and material sciences have greatly expanded the application fields, sophisticated the systems design and made the potential of electromagnetic NDE imaging seemingly unlimited. This review provides a comprehensive summary of research works on electromagnetic imaging methods for NDE applications, followed by the summary and discussions on future directions.

  10. A New Method of Photothermal Displacement Measurement by Laser Interferometric Probe —Its Mechanism and Applications to Evaluation of Lattice Damage in Semiconductors—

    NASA Astrophysics Data System (ADS)

    Sumie, Shingo; Takamatsu, Hiroyuki; Nishimoto, Yoshiro; Horiuchi, Takefumi; Nakayama, Hiroshi; Kanata, Takashi; Nishino, Taneo

    1992-11-01

    A new, highly sensitive technique for measuring photothermal displacement using a laser heterodyne interferometric probe has been developed. This technique is based on the detection of phase changes in the probe beam and is very sensitive to the presence of lattice damage in semiconductors. It has been found that the phase change is caused by the thermal expansion of a sample surface induced by absorption of a modulated pump beam. The displacements of metals and semiconductors measured by this technique coincided with the results predicted by a thermal diffusion model. These displacements simply depended upon the ratio of the thermal expansion coefficient to the thermal conductlvity of a sample.

  11. Interferometric SAR phase difference calibration: Methods and results

    SciTech Connect

    Bickel, D.L.; Hensley, W.H.

    1993-12-31

    This paper addresses the steps necessary to determine and maintain the phase calibration of a two-channel interferometric synthetic aperture radar (IFSAR). The method, setup, and accuracy of four different calibration techniques are compared. The most novel technique involves pointing the interferometric baseline at nadir and imaging a lake surface. The other techniques include measuring various flat surfaces in traditional side-looking IFSAR maps, in-flight closed-loop calibration path measurements, and static laboratory measurements. Initial results indicate that, using combinations of these measurements, it is possible to maintain the interferometric phase calibration of Sandia National Laboratories` K{sub U} Band IFSAR to better than 3 degrees. The time variability of various parts of the calibration and requirements for recalibration are also discussed.

  12. Mobile radio interferometric geodetic systems

    NASA Technical Reports Server (NTRS)

    Macdoran, P. F.; Niell, A. E.; Ong, K. M.; Resch, G. M.; Morabito, D. D.; Claflin, E. S.; Lockhart, T. G.

    1978-01-01

    Operation of the Astronomical Radio Interferometric Earth Surveying (ARIES) in a proof of concept mode is discussed. Accuracy demonstrations over a short baseline, a 180 km baseline, and a 380 km baseline are documented. Use of ARIES in the Sea Slope Experiment of the National Geodetic Survey to study the apparent differences between oceanographic and geodetic leveling determinations of the sea surface along the Pacific Coast is described. Intergration of the NAVSTAR Global Positioning System and a concept called SERIES (Satellite Emission Radio Interferometric Earth Surveying) is briefly reviewed.

  13. An extensible imaging platform for optical imaging applications

    NASA Astrophysics Data System (ADS)

    Paladini, Gianluca; Azar, Fred S.

    2009-02-01

    The National Institutes of Health (NIH) has recently developed an extensible imaging platform (XIP), a new open-source software development platform. XIP can be used to rapidly develop imaging applications designed to meet the needs of the optical imaging community. XIP is a state-of-the-art set of visual 'drag and drop' programming tools and associated libraries for rapid prototyping and application development. The tools include modules tailored for medical imaging, many of which are GPU hardware accelerated. They also provide a friendlier environment for utilizing popular toolkits such as ITK and VTK, and enable the visualization and processing of optical imaging data and standard DICOM data. XIP has built-in functionality for multidimensional data visualization and processing, and enables the development of independently optimized and re-usable software modules, which can be seamlessly added and interconnected to build advanced applications. XIP applications can run "stand alone", including in client/server mode for remote access. XIP also supports the DICOM WG23 "Application Hosting" standard, which will enable plug-in XIP applications to run on any DICOM host workstation. Such interoperability will enable the optical imaging community to develop and deploy modular applications across all academic/clinical/industry partners with WG23 compliant imaging workstations.

  14. Independent component analysis for improving the quality of interferometric products

    NASA Astrophysics Data System (ADS)

    Saqellari Likoka, A.; Vafeiadi-Bila, E.; Karathanassi, V.

    2016-05-01

    The accuracy of InSAR DEMs is affected by the temporal decorrelation of SAR images which is due to atmosphere, land use/cover, soil moisture, and roughness changes. Elimination of the temporal decorrelation of the master and slave image improves the DEMs accuracy. In this study, the Independent Component Analysis was applied before interferometric process. It was observed that using three ICA entries, ICA independent sources can be interpreted as background and changed images. ICA when performed on the master and slave images using the same couple of additional images produces two background images which enable the production of high quality DEMs. However, limitations exist in the proposed approach.

  15. New formulation for interferometric synthetic aperture radar for terrain mapping

    SciTech Connect

    Jakowatz, C.V. Jr.; Wahl, D.E.; Eichel, P.H.; Thompson, P.A.

    1994-04-01

    The subject of interferometric synthetic aperture radar (IFSAR) for high-accuracy terrain elevation mapping continues to gain importance in the arena of radar signal processing. Applications to problems in precision terrain-aided guidance and automatic target recognition, as well as a variety of civil applications, are being studied by a number of researchers. Not unlike many other areas of SAR processing, the subject of IFSAR can at first glance appear to be somewhat mysterious. In this paper we show how the mathematics of IFSAR for terrain elevation mapping using a pair of spotlight mode SAR collections can be derived in a very straightforward manner. Here, we employ an approach that relies entirely on three-dimensional Fourier transforms, and utilizes no reference to range equations or Doppler concepts. The result is a simplified explanation of the fundamentals of interferometry, including an easily-seen link between image domain phase difference and terrain elevation height. The derivation builds upon previous work by the authors in which a framework for spotlight mode SAR image formation based on an analogy to three-dimensional computerized axial tomography (CAT) was developed. After outlining the major steps in the mathematics, we show how a computer simulator which utilizes three-dimensional Fourier transforms can be constructed that demonstrates all of the major aspects of IFSAR from spotlight mode collections.

  16. Quantum interferometric measurements of temperature

    NASA Astrophysics Data System (ADS)

    Jarzyna, Marcin; Zwierz, Marcin

    2015-09-01

    We provide a detailed description of the quantum interferometric thermometer, which is a device that estimates the temperature of a sample from the measurements of the optical phase. We rigorously analyze the operation of such a device by studying the interaction of the optical probe system prepared in a single-mode Gaussian state with a heated sample modeled as a dissipative thermal reservoir. We find that this approach to thermometry is capable of measuring the temperature of a sample in the nanokelvin regime. Furthermore, we compare the fundamental precision of quantum interferometric thermometers with the theoretical precision offered by the classical idealized pyrometers, which infer the temperature from a measurement of the total thermal radiation emitted by the sample. We find that the interferometric thermometer provides a superior performance in temperature sensing even when compared with this idealized pyrometer. We predict that interferometric thermometers will prove useful for ultraprecise temperature sensing and stabilization of quantum optical experiments based on the nonlinear crystals and atomic vapors.

  17. Applications Of Image Processing In Criminalistics

    NASA Astrophysics Data System (ADS)

    Krile, Thomas F.; Walkup, John F.; Barsallo, Adonis; Olimb, Hal; Tarng, Jaw-Horng

    1987-01-01

    A review of some basic image processing techniques for enhancement and restoration of images is given. Both digital and optical approaches are discussed. Fingerprint images are used as examples to illustrate the various processing techniques and their potential applications in criminalistics.

  18. Imaging Strategies for Tissue Engineering Applications

    PubMed Central

    Nam, Seung Yun; Ricles, Laura M.; Suggs, Laura J.

    2015-01-01

    Tissue engineering has evolved with multifaceted research being conducted using advanced technologies, and it is progressing toward clinical applications. As tissue engineering technology significantly advances, it proceeds toward increasing sophistication, including nanoscale strategies for material construction and synergetic methods for combining with cells, growth factors, or other macromolecules. Therefore, to assess advanced tissue-engineered constructs, tissue engineers need versatile imaging methods capable of monitoring not only morphological but also functional and molecular information. However, there is no single imaging modality that is suitable for all tissue-engineered constructs. Each imaging method has its own range of applications and provides information based on the specific properties of the imaging technique. Therefore, according to the requirements of the tissue engineering studies, the most appropriate tool should be selected among a variety of imaging modalities. The goal of this review article is to describe available biomedical imaging methods to assess tissue engineering applications and to provide tissue engineers with criteria and insights for determining the best imaging strategies. Commonly used biomedical imaging modalities, including X-ray and computed tomography, positron emission tomography and single photon emission computed tomography, magnetic resonance imaging, ultrasound imaging, optical imaging, and emerging techniques and multimodal imaging, will be discussed, focusing on the latest trends of their applications in recent tissue engineering studies. PMID:25012069

  19. Brain Imaging: Applications in Psychiatry.

    ERIC Educational Resources Information Center

    Andreasen, Nancy C.

    1988-01-01

    Discusses various brain imaging techniques, including computed tomography, magnetic resonance imaging, measurement of regional cerebral blood flow, single photo emission tomography, and position emission tomography. Describes the uses of these techniques in helping to understand brain functioning. (TW)

  20. Full-field interferometric confocal microscopy using a VCSEL array.

    PubMed

    Redding, Brandon; Bromberg, Yaron; Choma, Michael A; Cao, Hui

    2014-08-01

    We present an interferometric confocal microscope using an array of 1200 vertical cavity surface emitting lasers (VCSELs) coupled to a multimode fiber. Spatial coherence gating provides ~18,000 continuous virtual pinholes, allowing an entire en face plane to be imaged in a snapshot. This approach maintains the same optical sectioning as a scanning confocal microscope without moving parts, while the high power of the VCSEL array (∼5  mW per laser) enables high-speed image acquisition with integration times as short as 100 μs. Interferometric detection also recovers the phase of the image, enabling quantitative phase measurements and improving the contrast when imaging phase objects. PMID:25078199

  1. Mass spectrometry imaging for biomedical applications

    PubMed Central

    Liu, Jiangjiang; Ouyang, Zheng

    2013-01-01

    The development of mass spectrometry imaging technologies is of significant current research interest. Mass spectrometry potentially is capable of providing highly specific information about the distribution of chemical compounds on tissues at highly sensitive levels. The required in-situ analysis for the tissue imaging forced MS analysis being performed off the traditional conditions optimized in pharmaceutical applications with intense sample preparation. This critical review seeks to present an overview of the current status of the MS imaging with different sampling ionization methods and to discuss the 3D imaging and quantitative imaging capabilities needed to be further developed, the importance of the multi-modal imaging, and a balance between the pursuit of the high imaging resolution and the practical application of MS imaging in biomedicine. PMID:23539099

  2. Principles and clinical applications of image analysis.

    PubMed

    Kisner, H J

    1988-12-01

    Image processing has traveled to the lunar surface and back, finding its way into the clinical laboratory. Advances in digital computers have improved the technology of image analysis, resulting in a wide variety of medical applications. Offering improvements in turnaround time, standardized systems, increased precision, and walkaway automation, digital image analysis has likely found a permanent home as a diagnostic aid in the interpretation of microscopic as well as macroscopic laboratory images.

  3. Graph theory for analyzing pair-wise data: application to geophysical model parameters estimated from interferometric synthetic aperture radar data at Okmok volcano, Alaska

    NASA Astrophysics Data System (ADS)

    Reinisch, Elena C.; Cardiff, Michael; Feigl, Kurt L.

    2016-07-01

    Graph theory is useful for analyzing time-dependent model parameters estimated from interferometric synthetic aperture radar (InSAR) data in the temporal domain. Plotting acquisition dates (epochs) as vertices and pair-wise interferometric combinations as edges defines an incidence graph. The edge-vertex incidence matrix and the normalized edge Laplacian matrix are factors in the covariance matrix for the pair-wise data. Using empirical measures of residual scatter in the pair-wise observations, we estimate the relative variance at each epoch by inverting the covariance of the pair-wise data. We evaluate the rank deficiency of the corresponding least-squares problem via the edge-vertex incidence matrix. We implement our method in a MATLAB software package called GraphTreeTA available on GitHub (https://github.com/feigl/gipht). We apply temporal adjustment to the data set described in Lu et al. (Geophys Res Solid Earth 110, 2005) at Okmok volcano, Alaska, which erupted most recently in 1997 and 2008. The data set contains 44 differential volumetric changes and uncertainties estimated from interferograms between 1997 and 2004. Estimates show that approximately half of the magma volume lost during the 1997 eruption was recovered by the summer of 2003. Between June 2002 and September 2003, the estimated rate of volumetric increase is (6.2 ± 0.6) × 10^6~m^3/year . Our preferred model provides a reasonable fit that is compatible with viscoelastic relaxation in the five years following the 1997 eruption. Although we demonstrate the approach using volumetric rates of change, our formulation in terms of incidence graphs applies to any quantity derived from pair-wise differences, such as range change, range gradient, or atmospheric delay.

  4. New applications of Spectral Edge image fusion

    NASA Astrophysics Data System (ADS)

    Hayes, Alex E.; Montagna, Roberto; Finlayson, Graham D.

    2016-05-01

    In this paper, we present new applications of the Spectral Edge image fusion method. The Spectral Edge image fusion algorithm creates a result which combines details from any number of multispectral input images with natural color information from a visible spectrum image. Spectral Edge image fusion is a derivative-based technique, which creates an output fused image with gradients which are an ideal combination of those of the multispectral input images and the input visible color image. This produces both maximum detail and natural colors. We present two new applications of Spectral Edge image fusion. Firstly, we fuse RGB-NIR information from a sensor with a modified Bayer pattern, which captures visible and near-infrared image information on a single CCD. We also present an example of RGB-thermal image fusion, using a thermal camera attached to a smartphone, which captures both visible and low-resolution thermal images. These new results may be useful for computational photography and surveillance applications.

  5. Balloon-based interferometric techniques

    NASA Technical Reports Server (NTRS)

    Rees, David

    1985-01-01

    A balloon-borne triple-etalon Fabry-Perot Interferometer, observing the Doppler shifts of absorption lines caused by molecular oxygen and water vapor in the far red/near infrared spectrum of backscattered sunlight, has been used to evaluate a passive spaceborne remote sensing technique for measuring winds in the troposphere and stratosphere. There have been two successful high altitude balloon flights of the prototype UCL instrument from the National Scientific Balloon Facility at Palestine, TE (May 80, Oct. 83). The results from these flights have demonstrated that an interferometer with adequate resolution, stability and sensitivity can be built. The wind data are of comparable quality to those obtained from operational techniques (balloon and rocket sonde, cloud-top drift analysis, and from the gradient wind analysis of satellite radiance measurements). However, the interferometric data can provide a regular global grid, over a height range from 5 to 50 km in regions of clear air. Between the middle troposphere (5 km) and the upper stratosphere (40 to 50 km), an optimized instrument can make wind measurements over the daylit hemisphere with an accuracy of about 3 to 5 m/sec (2 sigma). It is possible to obtain full height profiles between altitudes of 5 and 50 km, with 4 km height resolution, and a spatial resolution of about 200 km, along the orbit track. Below an altitude of about 10 km, Fraunhofer lines of solar origin are possible targets of the Doppler wind analysis. Above an altitude of 50 km, the weakness of the backscattered solar spectrum (decreasing air density) is coupled with the low absorption crosssection of all atmospheric species in the spectral region up to 800 nm (where imaging photon detectors can be used), causing the along-the-track resolution (or error) to increase beyond values useful for operational purposes. Within the region of optimum performance (5 to 50 km), however, the technique is a valuable potential complement to existing wind

  6. Interferometric synthetic aperture radar imagery of the Gulf Stream

    NASA Technical Reports Server (NTRS)

    Ainsworth, T. L.; Cannella, M. E.; Jansen, R. W.; Chubb, S. R.; Carande, R. E.; Foley, E. W.; Goldstein, R. M.; Valenzuela, G. R.

    1993-01-01

    The advent of interferometric synthetic aperture radar (INSAR) imagery brought to the ocean remote sensing field techniques used in radio astronomy. Whilst details of the interferometry differ between the two fields, the basic idea is the same: Use the phase information arising from positional differences of the radar receivers and/or transmitters to probe remote structures. The interferometric image is formed from two complex synthetic aperture radar (SAR) images. These two images are of the same area but separated in time. Typically the time between these images is very short -- approximately 50 msec for the L-band AIRSAR (Airborne SAR). During this short period the radar scatterers on the ocean surface do not have time to significantly decorrelate. Hence the two SAR images will have the same amplitude, since both obtain the radar backscatter from essentially the same object. Although the ocean surface structure does not significantly decorrelate in 50 msec, surface features do have time to move. It is precisely the translation of scattering features across the ocean surface which gives rise to phase differences between the two SAR images. This phase difference is directly proportional to the range velocity of surface scatterers. The constant of proportionality is dependent upon the interferometric mode of operation.

  7. Application of image fusion techniques in DSA

    NASA Astrophysics Data System (ADS)

    Ye, Feng; Wu, Jian; Cui, Zhiming; Xu, Jing

    2007-12-01

    Digital subtraction angiography (DSA) is an important technology in both medical diagnoses and interposal therapy, which can eliminate the interferential background and give prominence to blood vessels by computer processing. After contrast material is injected into an artery or vein, a physician produces fluoroscopic images. Using these digitized images, a computer subtracts the image made with contrast material from a series of post injection images made without background information. By analyzing the characteristics of DSA medical images, this paper provides a solution of image fusion which is in allusion to the application of DSA subtraction. We fuse the images of angiogram and subtraction, in order to obtain the new image which has more data information. The image that fused by wavelet transform can display the blood vessels and background information clearly, and medical experts gave high score on the effect of it.

  8. (Sub)millimetre interferometric imaging of a sample of COSMOS/AzTEC submillimetre galaxies. I. Multiwavelength identifications and redshift distribution

    NASA Astrophysics Data System (ADS)

    Miettinen, O.; Smolčić, V.; Novak, M.; Aravena, M.; Karim, A.; Masters, D.; Riechers, D. A.; Bussmann, R. S.; McCracken, H. J.; Ilbert, O.; Bertoldi, F.; Capak, P.; Feruglio, C.; Halliday, C.; Kartaltepe, J. S.; Navarrete, F.; Salvato, M.; Sanders, D.; Schinnerer, E.; Sheth, K.

    2015-05-01

    We used the Plateau de Bure Interferometer (PdBI) to map a sample of 15 submillimetre galaxies (SMGs) in the COSMOS field at the wavelength of 1.3 mm. The target SMGs were originally discovered in the James Clerk Maxwell Telescope (JCMT)/AzTEC 1.1 mm continuum survey at S/N1.1 mm = 4-4.5. This paper presents, for the first time, interferometric millimetre-wavelength observations of these sources. The angular resolution of our observations, 1''&dotbelow;8, allowed us to accurately determine the positions of the target SMGs. Using a detection threshold of S/N1.3 mm> 4.5 regardless of multiwavelength counterpart association, and 4

  9. Medical image informatics infrastructure design and applications.

    PubMed

    Huang, H K; Wong, S T; Pietka, E

    1997-01-01

    Picture archiving and communication systems (PACS) is a system integration of multimodality images and health information systems designed for improving the operation of a radiology department. As it evolves, PACS becomes a hospital image document management system with a voluminous image and related data file repository. A medical image informatics infrastructure can be designed to take advantage of existing data, providing PACS with add-on value for health care service, research, and education. A medical image informatics infrastructure (MIII) consists of the following components: medical images and associated data (including PACS database), image processing, data/knowledge base management, visualization, graphic user interface, communication networking, and application oriented software. This paper describes these components and their logical connection, and illustrates some applications based on the concept of the MIII. PMID:9509399

  10. Medical imaging applications of amorphous silicon

    SciTech Connect

    Mireshghi, A.; Drewery, J.S.; Hong, W.S.; Jing, T.; Kaplan, S.N.; Lee, H.K.; Perez-Mendez, V.

    1994-07-01

    Two dimensional hydrogenated amorphous silicon (a-Si:H) pixel arrays are good candidates as flat-panel imagers for applications in medical imaging. Various performance characteristics of these imagers are reviewed and compared with currently used equipments. An important component in the a-Si:H imager is the scintillator screen. A new approach for fabrication of high resolution CsI(Tl) scintillator layers, appropriate for coupling to a-Si:H arrays, are presented. For nuclear medicine applications, a new a-Si:H based gamma camera is introduced and Monte Carlo simulation is used to evaluate its performance.

  11. Multilanthanide Systems for Medical Imaging Applications

    PubMed Central

    Moore, Jeremiah D.; Allen, Matthew J.

    2011-01-01

    Molecules containing multiple lanthanide ions have unique potential in applications for medical imaging including the areas of magnetic resonance imaging (MRI) and fluoresence imaging. The study of multilanthanide complexes as contrast agents for MRI and as biologically responsive fluorescent probes has resulted in an improved understanding of the structural characteristics that govern the behavior of these complexes. This review will survey the last five years of progress in multinuclear lanthanide complexes with a specific focus on the structural parameters that impact potential medical imaging applications. The patents cited in this review are from the last five years and describe contrast agents that contain multiple lanthanide ions. PMID:23543789

  12. Lens-Free Imaging for Biological Applications

    PubMed Central

    Kim, Sang Bok; Bae, Hojae; Koo, Kyo-in; Dokmeci, Mehmet R.; Ozcan, Aydogan; Khademhosseini, Ali

    2013-01-01

    Lens-free (or lensless) imaging is emerging as a cost-effective, compact, and lightweight detection method that can serve numerous biological applications. Lens-free imaging can generate high-resolution images within a field-portable platform, which is ideal for affordable point-of-care devices aiming at resource-limited settings. In this mini-review, we first describe different modes of operation for lens-free imaging and then highlight several recent biological applications of this emerging platform technology. PMID:22357607

  13. Petrophysical applications of NMR imaging

    SciTech Connect

    Rothwell, W.P.; Vinegar, H.J.

    1985-12-01

    A system for obtaining high-resolution NMR images of oil field cores is described. Separate proton density and T/sub 2/ relaxation images are obtained to distinguish spatial variations of fluid-filled porosity and the physical nature of the pores. Results are presented for typical sandstones.

  14. Interferometric angle monitor

    NASA Technical Reports Server (NTRS)

    Minott, P. O. (Inventor)

    1983-01-01

    Two mutually coherent light beams formed from a single monochromatic light source were directed to a reflecting surface of a rotatable object. They were reflected into an imaging optical lens having a focal plane optically at infinity. A series of interference fringes were formed in the focal plane which were translated linearly in response to angular rotation of the object. Photodetectors were located adjacent the focal plane to detect the fringe translation and output a signal in response to the translation. The signal was fed to a signal processor which was adapted to count the number of fringes detected and develop a measure of the angular rotation and direction of the object.

  15. Passive terahertz imaging for security application

    NASA Astrophysics Data System (ADS)

    Guo, Lan-tao; Deng, Chao; Zhao, Yuan-meng; Zhang, Cun-lin

    2013-08-01

    The passive detection is safe for passengers and operators as no radiation. Therefore, passive terahertz (THz) imaging can be applied to human body security check. Imaging in the THz band offers the unique property of being able to identify object through a range of materials. Therefore passive THz imaging is meaningful for security applications. This attribute has always been of interest to both the civil and military marks with applications. We took advantage of a single THz detector and a trihedral scanning mirror to propose another passive THz beam scanning imaging method. This method overcame the deficiencies of the serious decline in image quality due to the movement of the focused mirror. We exploited a THz scanning mirror with a trihedral scanning mirror and an ellipsoidal mirror to streamline the structure of the system and increase the scanning speed. Then the passive THz beam scanning imaging system was developed based on this method. The parameters were set as follows: the best imaging distance was 1.7m, the image height was 2m, the image width was 1m, the minimum imaging time of per frame was 8s, and the minimum resolution was 4cm. We imaged humans with different objects hidden under their clothes, such as fruit knife, belt buckle, mobile phone, screwdriver, bus cards, keys and other items. All the tested stuffs could be detected and recognized from the image.

  16. Photoacoustic lifetime imaging and its biomedical applications

    NASA Astrophysics Data System (ADS)

    Shao, Qi

    Even though oxygen plays a crucial role in body function and cancer biology, methods of measuring oxygen level in tissue are all limited. The current gold standard relies on an invasive electrode for only single-point reading at a time. The photoacoustic lifetime imaging (PALI) approach overcomes these major limitations by applying photoacoustic probing to oxygen-sensitive optical transient absorption. The capability of assessing oxygen distribution is demonstrated by imaging tumor hypoxia in a small animal model, and monitoring changes of tissue oxygen induced by external modulations. Proposed applications of this imaging technique includes imaging-guided photodynamic therapy (PDT) and activatable probes for molecular imaging.

  17. Principle and applications of terahertz molecular imaging.

    PubMed

    Son, Joo-Hiuk

    2013-05-31

    The principle, characteristics and applications of molecular imaging with terahertz electromagnetic waves are reviewed herein. The terahertz molecular imaging (TMI) technique uses nanoparticle probes to achieve dramatically enhanced sensitivity compared with that of conventional terahertz imaging. Surface plasmons, induced around the nanoparticles, raise the temperature of water in biological cells, and the temperature-dependent changes in the optical properties of water, which are large in the terahertz range, are measured differentially by terahertz waves. TMI has been applied to cancer diagnosis and nanoparticle drug delivery imaging. The technique is also compared with magnetic resonance imaging by using a dual-modality nanoparticle probe.

  18. Interferometric observation of microlensing events

    NASA Astrophysics Data System (ADS)

    Cassan, Arnaud; Ranc, Clément

    2016-05-01

    Interferometric observations of microlensing events have the potential to provide unique constraints on the physical properties of the lensing systems. In this work, we first present a formalism that closely combines interferometric and microlensing observable quantities, which lead us to define an original microlensing (u, v) plane. We run simulations of long-baseline interferometric observations and photometric light curves to decide which observational strategy is required to obtain a precise measurement on vector Einstein radius. We finally perform a detailed analysis of the expected number of targets in the light of new microlensing surveys (2011+) which currently deliver 2000 alerts per year. We find that a few events are already at reach of long-baseline interferometers (CHARA, VLTI), and a rate of about six events per year is expected with a limiting magnitude of K ≃ 10. This number would increase by an order of magnitude by raising it to K ≃ 11. We thus expect that a new route for characterizing microlensing events will be opened by the upcoming generations of interferometers.

  19. The Space Infrared Interferometric Telescope (SPIRIT)

    NASA Technical Reports Server (NTRS)

    Leisawitz, David

    2005-01-01

    We report preliminary results of a study of the Space Infrared Interferometric Telescope (SPIRIT), a candidate Origins Probe mission. SPIRIT is a two-element Michelson interferometer operating over a nominal wavelength range 25 to 400 microns and offering a powerful combination of spectroscopy and sub-arcsecond angular resolution imaging in a single instrument. With angular resolution comparable to that of JWST and far-IR sensitivity nearly two orders of magnitude better than that of the Spitzer Space Telescope, SPIRIT will measure the resonant structures in exozodi debris disks to find and characterize extrasolar planets; characterize the atmospheres of selected extrasolar gas giant planets; elucidate the evolution of young stellar systems and their planet-forming potential; and track the luminosity evolution and chemical and dust enrichment of galaxies on a cosmological timescale. SPIRIT could be ready to launch as early as 2015. The SPIRIT study is sponsored by NASA under the Origins Science Mission Concept study program.

  20. Simultaneous CARS and Interferometric Rayleigh Scattering

    NASA Technical Reports Server (NTRS)

    Bivolaru, Daniel; Danehy, Paul M.; Grinstead, Keith D., Jr.; Tedder, Sarah; Cutler, Andrew D.

    2006-01-01

    This paper reports for the first time the combination of a dual-pump coherent anti-Stokes Raman scattering system with an interferometric Rayleigh scattering system (CARS - IRS) to provide time-resolved simultaneous measurement of multiple properties in combustion flows. The system uses spectrally narrow green (seeded Nd:YAG at 532 nm) and yellow (552.9 nm) pump beams and a spectrally-broad red (607 nm) beam as the Stokes beam. A spectrometer and a planar Fabry-Perot interferometer used in the imaging mode are used to record the spectrally broad CARS spectra and the spontaneous Rayleigh scattering spectra, respectively. Time-resolved simultaneous measurement of temperature, absolute mole fractions of N2, O2, and H2, and two components of velocity in a Hencken burner flame were performed to demonstrate the technique.

  1. The Space Infrared Interferometric Telescope (SPIRIT)

    NASA Technical Reports Server (NTRS)

    Leisawitz, David T.

    2014-01-01

    The far-infrared astrophysics community is eager to follow up Spitzer and Herschel observations with sensitive, high-resolution imaging and spectroscopy, for such measurements are needed to understand merger-driven star formation and chemical enrichment in galaxies, star and planetary system formation, and the development and prevalence of water-bearing planets. The Space Infrared Interferometric Telescope (SPIRIT) is a wide field-of-view space-based spatio-spectral interferometer designed to operate in the 25 to 400 micron wavelength range. This talk will summarize the SPIRIT mission concept, with a focus on the science that motivates it and the technology that enables it. Without mentioning SPIRIT by name, the astrophysics community through the NASA Astrophysics Roadmap Committee recently recommended this mission as the first in a series of space-based interferometers. Data from a laboratory testbed interferometer will be used to illustrate how the spatio-spectral interferometry technique works.

  2. CMOS imager for pointing and tracking applications

    NASA Technical Reports Server (NTRS)

    Pain, Bedabrata (Inventor); Sun, Chao (Inventor); Yang, Guang (Inventor); Heynssens, Julie B. (Inventor)

    2006-01-01

    Systems and techniques to realize pointing and tracking applications with CMOS imaging devices. In general, in one implementation, the technique includes: sampling multiple rows and multiple columns of an active pixel sensor array into a memory array (e.g., an on-chip memory array), and reading out the multiple rows and multiple columns sampled in the memory array to provide image data with reduced motion artifact. Various operation modes may be provided, including TDS, CDS, CQS, a tracking mode to read out multiple windows, and/or a mode employing a sample-first-read-later readout scheme. The tracking mode can take advantage of a diagonal switch array. The diagonal switch array, the active pixel sensor array and the memory array can be integrated onto a single imager chip with a controller. This imager device can be part of a larger imaging system for both space-based applications and terrestrial applications.

  3. Image informatics in systems biology applications

    NASA Astrophysics Data System (ADS)

    Wong, Stephen T. C.

    2005-02-01

    Digital optical microscopy, coupled with parallel processing and a large arsenal of labeling techniques, offers tremendous values to localize, identify, and characterize cells and molecules. This generates many image informatics challenges in requiring new algorithms and tools to extract, classify, correlate, and model image features and content from massive amounts of cellular and molecular images acquired. Image informatics aims to fill this gap. Coupling automated microscopy and image analysis with biostatistical and data mining techniques to provide a system biologic approach in studying the cells, the basic unit of life, potentially leads to many exciting applications in life and health sciences. In this presentation, we describe certain new system biology applications enabled by image informatics technology.

  4. Prior image constrained image reconstruction in emerging computed tomography applications

    NASA Astrophysics Data System (ADS)

    Brunner, Stephen T.

    Advances have been made in computed tomography (CT), especially in the past five years, by incorporating prior images into the image reconstruction process. In this dissertation, we investigate prior image constrained image reconstruction in three emerging CT applications: dual-energy CT, multi-energy photon-counting CT, and cone-beam CT in image-guided radiation therapy. First, we investigate the application of Prior Image Constrained Compressed Sensing (PICCS) in dual-energy CT, which has been called "one of the hottest research areas in CT." Phantom and animal studies are conducted using a state-of-the-art 64-slice GE Discovery 750 HD CT scanner to investigate the extent to which PICCS can enable radiation dose reduction in material density and virtual monochromatic imaging. Second, we extend the application of PICCS from dual-energy CT to multi-energy photon-counting CT, which has been called "one of the 12 topics in CT to be critical in the next decade." Numerical simulations are conducted to generate multiple energy bin images for a photon-counting CT acquisition and to investigate the extent to which PICCS can enable radiation dose efficiency improvement. Third, we investigate the performance of a newly proposed prior image constrained scatter correction technique to correct scatter-induced shading artifacts in cone-beam CT, which, when used in image-guided radiation therapy procedures, can assist in patient localization, and potentially, dose verification and adaptive radiation therapy. Phantom studies are conducted using a Varian 2100 EX system with an on-board imager to investigate the extent to which the prior image constrained scatter correction technique can mitigate scatter-induced shading artifacts in cone-beam CT. Results show that these prior image constrained image reconstruction techniques can reduce radiation dose in dual-energy CT by 50% in phantom and animal studies in material density and virtual monochromatic imaging, can lead to radiation

  5. Small pixel uncooled imaging FPAs and applications

    NASA Astrophysics Data System (ADS)

    Blackwell, Richard; Franks, Glen; Lacroix, Daniel; Hyland, Sandra; Murphy, Robert

    2010-04-01

    BAE Systems continues to make dramatic progress in uncooled microbolometer sensors and applications. This paper will review the latest advancements in microbolometer technology at BAE Systems, including the development status of 17 micrometer pixel pitch detectors and imaging modules which are entering production and will be finding their way into BAE Systems products and applications. Benefits include increased die per wafer and potential benefits to SWAP for many applications. Applications include thermal weapons sights, thermal imaging modules for remote weapon stations, vehicle situational awareness sensors and mast/pole mounted sensors.

  6. Thermosonic imaging of cracks: applications to teeth

    NASA Astrophysics Data System (ADS)

    Han, Xiaoyan; Favro, Lawrence D.; Thomas, Robert L.

    2001-10-01

    A novel nondestructive imaging technique, thermosonics, which combines ultrasonic/sonic excitation and advanced infrared imaging, will be described. In this paper, the authors will illuminate the physical principles underlining this technique, and demonstrate its applications to detection of cracks in teeth.

  7. Image processing applications in NDE

    SciTech Connect

    Morris, R.A.

    1980-01-01

    Nondestructive examination (NDE) can be defined as a technique or collection of techniques that permits one to determine some property of a material or object without damaging the object. There are a large number of such techniques and most of them use visual imaging in one form or another. They vary from holographic interferometry where displacements under stress are measured to the visual inspection of an objects surface to detect cracks after penetrant has been applied. The use of image processing techniques on the images produced by NDE is relatively new and can be divided into three general categories: classical image enhancement; mensuration techniques; and quantitative sensitometry. An example is discussed of how image processing techniques are used to nondestructively and destructively test the product throughout its life cycle. The product that will be followed is the microballoon target used in the laser fusion program. The laser target is a small (50 to 100 ..mu..m - dia) glass sphere with typical wall thickness of 0.5 to 6 ..mu..m. The sphere may be used as is or may be given a number of coatings of any number of materials. The beads are mass produced by the millions and the first nondestructive test is to separate the obviously bad beads (broken or incomplete) from the good ones. After this has been done, the good beads must be inspected for spherocity and wall thickness uniformity. The microradiography of the glass, uncoated bead is performed on a specially designed low-energy x-ray machine. The beads are mounted in a special jig and placed on a Kodak high resolution plate in a vacuum chamber that contains the x-ray source. The x-ray image is made with an energy less that 2 keV and the resulting images are then inspected at a magnification of 500 to 1000X. Some typical results are presented.

  8. Intelligent imaging systems for automotive applications

    NASA Astrophysics Data System (ADS)

    Thompson, Chris; Huang, Yingping; Fu, Shan

    2004-03-01

    In common with many other application areas, visual signals are becoming an increasingly important information source for many automotive applications. For several years CCD cameras have been used as research tools for a range of automotive applications. Infrared cameras, RADAR and LIDAR are other types of imaging sensors that have also been widely investigated for use in cars. This paper will describe work in this field performed in C2VIP over the last decade - starting with Night Vision Systems and looking at various other Advanced Driver Assistance Systems. Emerging from this experience, we make the following observations which are crucial for "intelligent" imaging systems: 1. Careful arrangement of sensor array. 2. Dynamic-Self-Calibration. 3. Networking and processing. 4. Fusion with other imaging sensors, both at the image level and the feature level, provides much more flexibility and reliability in complex situations. We will discuss how these problems can be addressed and what are the outstanding issues.

  9. Propagation of spatial pulses in interferometrically produced guiding structures.

    PubMed

    Kung, G C; Leith, E N

    1975-11-01

    Image transfer properties of interferometrically produced dielectric light guides are investigated. A general technique of analysis is developed. Computer calculations based on this approach are used to study the behavior of pulses traversing the guiding structures for various values of refractive index. Experimental results are obtained using photosensitized polymethyl methacrylate as the recording material. Computer results are compared with existing theory and found to be in close agreement.

  10. Interferometric measurements of fine corneal topography

    NASA Astrophysics Data System (ADS)

    Kasprzak, Henryk T.; Kowalik, Waldemar; Jaronski, Jaroslaw W.

    1995-02-01

    The cornea is the most refractive element in the eye. Its refractive power is about 70% of the power of the whole eye. The shape of the cornea is aspheric, and almost always has no rotational symmetry. Even small surface irregularities can cause a perceptible reduction in visual acuity. Standard methods for evaluation of the corneal topography used in clinical practice include keratometry, photokeratoscopy, and computer assisted videokeratography. All of these methods used the principles of geometrical optics, and their accuracy is about 0.25 D. An application of interference phenomenon's to examine the corneal contour map significantly increase the accuracy. Using the interferometric inspection of the corneal shape one can easily observe the fine corneal topography, the fast, dynamic changes of the corneal surface, and the topology of the tear film and its irregularities. The paper presents the Twyman Green interferometer, used in experiments, an example of sequence of interferograms and their 3D presentations.

  11. Single-exposure super-resolved interferometric microscopy by RGB multiplexing in lensless configuration

    NASA Astrophysics Data System (ADS)

    Granero, Luis; Ferreira, Carlos; Zalevsky, Zeev; García, Javier; Micó, Vicente

    2016-07-01

    Single-Exposure Super-Resolved Interferometric Microscopy (SESRIM) reports on a way to achieve one-dimensional (1-D) superresolved imaging in digital holographic microscopy (DHM) by a single illumination shot and digital recording. SESRIM provides color-coded angular multiplexing of the accessible sample's range of spatial frequencies and it allows their recording in a single CCD (color or monochrome) snapshot by adding 3 RGB coherent reference beams at the output plane. In this manuscript, we extend the applicability of SESRIM to the field of digital in-line holographic microscopy (DIHM), that is, working without lenses. As consequence of the in-line configuration, an additional restriction concerning the object field of view (FOV) must be imposed to the technique. Experimental results are reported for both a synthetic object (USAF resolution test target) and a biological sample (swine sperm sample) validating this new kind of superresolution imaging method named as lensless SESRIM (L-SESRIM).

  12. Spectral modulation interferometry for quantitative phase imaging

    PubMed Central

    Shang, Ruibo; Chen, Shichao; Li, Chengshuai; Zhu, Yizheng

    2015-01-01

    We propose a spectral-domain interferometric technique, termed spectral modulation interferometry (SMI), and present its application to high-sensitivity, high-speed, and speckle-free quantitative phase imaging. In SMI, one-dimensional complex field of an object is interferometrically modulated onto a broadband spectrum. Full-field phase and intensity images are obtained by scanning along the orthogonal direction. SMI integrates the high sensitivity of spectral-domain interferometry with the high speed of spectral modulation to quantify fast phase dynamics, and its dispersive and confocal nature eliminates laser speckles. The principle and implementation of SMI are discussed. Its performance is evaluated using static and dynamic objects. PMID:25780737

  13. Application of imaging geodesy to assess kinematics of the Medicine Wheel Landslide, Big Horn Mountains, Wyoming

    NASA Astrophysics Data System (ADS)

    Held, B. M.; Gomez, F.; Corley, J.

    2012-12-01

    Radar interferometry provides a means of imaging spatially varying kinematics of slow mass movements, such as earthflows. These observations provide critical constraints for understanding earth flow mechanics when considered with topography and meteorological forcings. This study focuses the Medicine Wheel Landslide located on the western side of the Big Horn Mountains in Wyoming. The mass movement is 1km by 1km and is on a 7 degree slope and consists of multiple rotational slumps within the larger mass which is detaching along the Mowry and Thermopolis Shales. The slide regularly damages the highway that intersects it. Preliminary results of a combination of satellite-based and ground-based radar interferometry document variations in the rates of done-slope movement. Satellite interferometric synthetic aperture radar (InSAR) analysis utilized L-band data acquired by the ALOS PALSAR system. Resulting interferograms indicated that the Medicine Wheel Slide is active even during the summer months moving up to 7.5cm from July to October 2011. This movement corresponds with record amounts of snowfall during the 2010-2011 winter. Ground based interferometric radar (GBIR) was chosen for this application due to millimeter scale sensitivity to motion, and its ability to perform observations from the same point. GBIR observation point was chosen to maximize line-of-site sensitivity to motion and to provide a more complete view of the entire slide surface. In addition, ground truth measurements of displacement are provided by a network of 20 monuments measured using rapid static GPS, acquired during the same observation campaign as the GBIR imaging. Seasonal amounts of movement derived from radar interferometry and ground-truthed by GPS, can then be compared meteorological data to determine if the relationship shown for 2011 persists.

  14. Development of the interferometrical scanning probe microscope

    NASA Astrophysics Data System (ADS)

    Dorozhovets, N.; Hausotte, T.; Hofmann, N.; Manske, E.; Jäger, G.

    2006-08-01

    Many scanning probe microscopes (SPMs) are used as image acquisition tools in such industries as microelectronics, micromechanics, lithography and biotechnology. Conventional SPMs use piezoelectric actuators in order to move either the sample or the probe. The voltage across the piezos is taken as a position indicator. However, it is known that piezos suffer from hysteresis, and from time- and temperature-dependent creep. A solution to this problem is provided by accurate, traceable measurement of the cantilever position. An exact dimensional measurement can only take place via direct comparison with a well-known reference. The traceability of the SPM can be achieved using an interferometer, traceable to the 633 nm wavelength of the He-Ne laser. For accurate measurements the position of the cantilever must be measured in addition to the torsion and bending. This article shows the basic SPM principle as well as the addition of a cantilever position detection system. This system has been realized with a special interferometer with a quadrant diode to detect the cantilever torsion and bending. The measuring beam is focused on the cantilever backside using a lens. The reflected laser beam is split and evaluated; one part of the beam is used for the interferometrical position measurement with the other part focused onto a quadrant diode. Due to the structure of the interferometrical SPM, it can be installed in many different positioning systems with large measuring ranges, including a nanopositioning and nanomeasuring machine (NPM machine), developed at the Institute of Process Measurement and Sensor Technology of the Technische Universitaet Ilmenau.

  15. Interferometric phase reconstruction using simplified coherence network

    NASA Astrophysics Data System (ADS)

    Zhang, Kui; Song, Ruiqing; Wang, Hui; Wu, Di; Wang, Hua

    2016-09-01

    Interferometric time-series analysis techniques, which extend the traditional differential radar interferometry, have demonstrated a strong capability for monitoring ground surface displacement. Such techniques are able to obtain the temporal evolution of ground deformation within millimeter accuracy by using a stack of synthetic aperture radar (SAR) images. In order to minimize decorrelation between stacked SAR images, the phase reconstruction technique has been developed recently. The main idea of this technique is to reform phase observations along a SAR stack by taking advantage of a maximum likelihood estimator which is defined on the coherence matrix estimated from each target. However, the phase value of a coherence matrix element might be considerably biased when its corresponding coherence is low. In this case, it will turn to an outlying sample affecting the corresponding phase reconstruction process. In order to avoid this problem, a new approach is developed in this paper. This approach considers a coherence matrix element to be an arc in a network. A so-called simplified coherence network (SCN) is constructed to decrease the negative impact of outlying samples. Moreover, a pointed iterative strategy is designed to resolve the transformed phase reconstruction problem defined on a SCN. For validation purposes, the proposed method is applied to 29 real SAR images. The results demonstrate that the proposed method has an excellent computational efficiency and could obtain more reliable phase reconstruction solutions compared to the traditional method using phase triangulation algorithm.

  16. Spaceborne radar applications in geology. An introduction to imaging radar and application examples of ERS SAR in geology and geomorphology

    NASA Astrophysics Data System (ADS)

    Fletcher, Karen

    2005-12-01

    This document is intended for geologists who are interested in broadening their knowledge of interpretation of imaging radar data, but also addresses the general public for reference and information. It introduces imaging radar as it may be used by technicians and image interpreters, stressing the use of synthetic aperture radar (SAR) for Earth observation in general and for geology in particular. Interferometric SAR is briefly treated, with some basic and practical hints. An illustrated application study on land subsidence is included. SAR/optical data fusion is explained, with examples of the different methods suggested. The main part of the document, part II, consists of 14 case studies that demonstrate the potential of SAR imagery for geology. These studies cover themes such as the detection and mapping of neotectonic activity, tectonic mapping, and recognition of karst structures, as well as analysis of active lahars and other volcanic events. They look into drainage systems in desert areas, consider lithofacies changes and morphostructure texture analysis, and they demonstrate the geological mapping of active tectonic compression. Finally, the document mentions the key points of the ESA SAR missions. Contacts for further information are also provided.

  17. Frequency modulated lasers for interferometric optical gyroscopes.

    PubMed

    Komljenovic, Tin; Tran, Minh A; Belt, Michael; Gundavarapu, Sarat; Blumenthal, Daniel J; Bowers, John E

    2016-04-15

    We study the use of frequency modulated lasers in interferometric optical gyroscopes and show that by exploiting various frequency modulation signals, the laser coherence can be controlled. We show that both angle random walk and bias stability of an interferometric optical gyroscope based on laser sources can be improved with this technique. PMID:27082342

  18. Imaging spectrometry - Technology and applications

    NASA Technical Reports Server (NTRS)

    Solomon, Jerry E.

    1989-01-01

    The development history and current status of NASA imaging-spectrometer (IS) technology are discussed in a review covering the period 1982-1988. Consideration is given to the Airborne IS first flown in 1982, the second-generation Airborne Visible and IR IS (AVIRIS), the High-Resolution IS being developed for the EOS polar platform, improved two-dimensional focal-plane arrays for the short-wave IR spectral region, and noncollinear acoustooptic tunable filters for use as spectral dispersing elements. Also examined are approaches to solving the data-processing problems posed by the high data volumes of state-of-the-art ISs (e.g., 160 MB per 600 x 600-pixel AVIRIS scene), including intelligent data editing, lossless and lossy data compression techniques, and direct extraction of scientifically meaningful geophysical and biophysical parameters.

  19. ICG fluorescence imaging and its medical applications

    NASA Astrophysics Data System (ADS)

    Miwa, Mitsuharu; Shikayama, Takahiro

    2008-12-01

    This paper presents a novel optical angiography system, and introduces its medical applications. We developed the optical enhanced imaging system which can observe the blood and lymphatic vessels as the Indocyanine green (ICG) fluorescence image. The imaging system consists of 760nm light emitted diode (LED) as excite light, CCD camera as a detector, a high-pass optical filter in front of the CCD and video processing system. The advantage of ICG fluorescence method is safe (radiation free), high sensitive, real time monitoring of blood and/or lymphatic flow, small size, easy to operate and cost effective compared to conventional X-ray angiography or scintigraphy. We have applied this method to several clinical applications such as breast cancer sentinel lymph node (SLN) navigation, lymph edema diagnostic and identification of liver segmentation. In each application, ICG fluorescence method shows useful result. It's indicated that this method is promising technique as optical angiography.

  20. Acoustic Location of Lightning Using Interferometric Techniques

    NASA Astrophysics Data System (ADS)

    Erives, H.; Arechiga, R. O.; Stock, M.; Lapierre, J. L.; Edens, H. E.; Stringer, A.; Rison, W.; Thomas, R. J.

    2013-12-01

    Acoustic arrays have been used to accurately locate thunder sources in lightning flashes. The acoustic arrays located around the Magdalena mountains of central New Mexico produce locations which compare quite well with source locations provided by the New Mexico Tech Lightning Mapping Array. These arrays utilize 3 outer microphones surrounding a 4th microphone located at the center, The location is computed by band-passing the signal to remove noise, and then computing the cross correlating the outer 3 microphones with respect the center reference microphone. While this method works very well, it works best on signals with high signal to noise ratios; weaker signals are not as well located. Therefore, methods are being explored to improve the location accuracy and detection efficiency of the acoustic location systems. The signal received by acoustic arrays is strikingly similar to th signal received by radio frequency interferometers. Both acoustic location systems and radio frequency interferometers make coherent measurements of a signal arriving at a number of closely spaced antennas. And both acoustic and interferometric systems then correlate these signals between pairs of receivers to determine the direction to the source of the received signal. The primary difference between the two systems is the velocity of propagation of the emission, which is much slower for sound. Therefore, the same frequency based techniques that have been used quite successfully with radio interferometers should be applicable to acoustic based measurements as well. The results presented here are comparisons between the location results obtained with current cross correlation method and techniques developed for radio frequency interferometers applied to acoustic signals. The data were obtained during the summer 2013 storm season using multiple arrays sensitive to both infrasonic frequency and audio frequency acoustic emissions from lightning. Preliminary results show that

  1. Spaceborne imaging radar - Geologic and oceanographic applications

    NASA Technical Reports Server (NTRS)

    Elachi, C.

    1980-01-01

    Synoptic, large-area radar images of the earth's land and ocean surface, obtained from the Seasat orbiting spacecraft, show the potential for geologic mapping and for monitoring of ocean surface patterns. Structural and topographic features such as lineaments, anticlines, folds and domes, drainage patterns, stratification, and roughness units can be mapped. Ocean surface waves, internal waves, current boundaries, and large-scale eddies have been observed in numerous images taken by the Seasat imaging radar. This article gives an illustrated overview of these applications.

  2. Spaceborne imaging radar: geologic and oceanographic applications.

    PubMed

    Elachi, C

    1980-09-01

    Synoptic, large-area radar images of the earth's land and ocean surface, obtained from the Seasat orbiting spacecraft, show the potential for geologic mapping and for monitoring of ocean surface patterns. Structural and topographic features such as lineaments, anticlines, folds and domes, drainage patterns, stratification, and roughness units can be mapped. Ocean surface waves, internal waves, current boundaries, and large-scale eddies have been observed in numerous images taken by the Seasat imaging radar. This article gives an illustrated overview of these applications.

  3. Reflectometric measurement of plasma imaging and applications

    NASA Astrophysics Data System (ADS)

    Mase, A.; Ito, N.; Oda, M.; Komada, Y.; Nagae, D.; Zhang, D.; Kogi, Y.; Tobimatsu, S.; Maruyama, T.; Shimazu, H.; Sakata, E.; Sakai, F.; Kuwahara, D.; Yoshinaga, T.; Tokuzawa, T.; Nagayama, Y.; Kawahata, K.; Yamaguchi, S.; Tsuji-Iio, S.; Domier, C. W.; Luhmann, N. C., Jr.; Park, H. K.; Yun, G.; Lee, W.; Padhi, S.; Kim, K. W.

    2012-01-01

    Progress in microwave and millimeter-wave technologies has made possible advanced diagnostics for application to various fields, such as, plasma diagnostics, radio astronomy, alien substance detection, airborne and spaceborne imaging radars called as synthetic aperture radars, living body measurements. Transmission, reflection, scattering, and radiation processes of electromagnetic waves are utilized as diagnostic tools. In this report we focus on the reflectometric measurements and applications to biological signals (vital signal detection and breast cancer detection) as well as plasma diagnostics, specifically by use of imaging technique and ultra-wideband radar technique.

  4. Determining the operating characteristics of an ultraviolet interferometric spectrometer

    NASA Technical Reports Server (NTRS)

    Parsons, C. L.

    1983-01-01

    A prototype interferometric spectrometer system is being built by NASA to explore the potential of the technique for applications involving the visible and near ultraviolet portions of the electromagnetic spectrum. The system is limited only by the frequency bandpass of the optical components used in the system, the quality of the optical components, and ultimately by the memory capacity of the computer; tradeoffs between the wavenumber resolution of the produced spectrum, the bandpass limits of the optics, and the number of samples obtained from the interferogram must be delineated explicitly. The prototype Ultraviolet Interferometric Spectrometer (UVIS) instrument is expected to be configured several different ways to ascertain its suitability for various applications. To exploit its inherent flexibility, this reference document describes these parameter tradeoffs.

  5. General adaptive-neighborhood technique for improving synthetic aperture radar interferometric coherence estimation.

    PubMed

    Vasile, Gabriel; Trouvé, Emmanuel; Ciuc, Mihai; Buzuloiu, Vasile

    2004-08-01

    A new method for filtering the coherence map issued from synthetic aperture radar (SAR) interferometric data is presented. For each pixel of the interferogram, an adaptive neighborhood is determined by a region-growing technique driven by the information provided by the amplitude images. Then pixels in the derived adaptive neighborhood are complex averaged to yield the filtered value of the coherence, after a phase-compensation step is performed. An extension of the algorithm is proposed for polarimetric interferometric SAR images. The proposed method has been applied to both European Remote Sensing (ERS) satellite SAR images and airborne high-resolution polarimetric interferometric SAR images. Both subjective and objective performance analysis, including coherence edge detection, shows that the proposed method provides better results than the standard phase-compensated fixed multilook filter and the Lee adaptive coherence filter.

  6. System Engineering the Space Infrared Interferometric Telescope (SPIRIT)

    NASA Technical Reports Server (NTRS)

    Hyde, Tristram T.; Leisawitz, David T.; Rinehart, Stephen

    2007-01-01

    The Space Infrared Interferometric Telescope (SPIRIT) was designed to accomplish three scientific objectives: (1) learn how planetary systems form from protostellar disks and how they acquire their inhomogeneous chemical composition; (2) characterize the family of extrasolar planetary systems by imaging the structure in debris disks to understand how and where planets of different types form; and (3) learn how high-redshift galaxies formed and merged to form the present-day population of galaxies. SPIRIT will accomplish these objectives through infrared observations with a two aperture interferometric instrument. This paper gives an overview of SPIRIT design and operation, and how the three design cycle concept study was completed. The error budget for several key performance values allocates tolerances to all contributing factors, and a performance model of the spacecraft plus instrument system demonstrates meeting those allocations with margin.

  7. Simulation of an interferometric computed tomography system for intraocular lenses

    NASA Astrophysics Data System (ADS)

    Tayag, Tristan J.; Bachim, Brent L.

    2010-08-01

    In this paper, we present a metrology system to characterize the refractive index profile of intraocular lenses (IOLs). Our system is based on interferometric optical phase computed tomography. We believe this metrology system to be a key enabling technology in the development of the next generation of IOLs. We propose a Fizeau-based optical configuration and present a simulation study on the application of computed tomography to IOL characterization.

  8. Novel hemispheric image formation: concepts and applications

    NASA Astrophysics Data System (ADS)

    Thibault, Simon; Konen, Pierre; Roulet, Patrice; Villegas, Mathieu

    2008-04-01

    Panoramic and hemispheric lens technologies represent new and exciting opportunities in both imaging and projection systems. Such lenses offer intriguing applications for the transportation/automotive industry, in the protection of civilian and military areas, business. In this paper we describe a new optical design technique that provides a greater degree of freedom in producing a variety of hemispheric spatial light distribution areas. This innovative optical design strategy, of generating and controlling image mapping, has been successful in producing high-resolution imaging and projection systems. This success has subsequently generated increased interest in the high-resolution camera/projector and the concept of absolute measurement with high-resolution wide-angle lenses. The new technique described in this paper uses optimization techniques to improve the performance of a customized wide-angle lens optical system for a specific application. By adding a custom angle-to-pixel ratio at the optical design stage, this customized optical system provides ideal image coverage while reducing and optimizing signal processing. This novel image formation technique requires the development of new algorithms in order to view the panoramic image on a display without any residual distortion.

  9. Fundus autofluorescence applications in retinal imaging

    PubMed Central

    Gabai, Andrea; Veritti, Daniele; Lanzetta, Paolo

    2015-01-01

    Fundus autofluorescence (FAF) is a relatively new imaging technique that can be used to study retinal diseases. It provides information on retinal metabolism and health. Several different pathologies can be detected. Peculiar AF alterations can help the clinician to monitor disease progression and to better understand its pathogenesis. In the present article, we review FAF principles and clinical applications. PMID:26139802

  10. Recent applications of hyperspectral imaging in microbiology.

    PubMed

    Gowen, Aoife A; Feng, Yaoze; Gaston, Edurne; Valdramidis, Vasilis

    2015-05-01

    Hyperspectral chemical imaging (HSI) is a broad term encompassing spatially resolved spectral data obtained through a variety of modalities (e.g. Raman scattering, Fourier transform infrared microscopy, fluorescence and near-infrared chemical imaging). It goes beyond the capabilities of conventional imaging and spectroscopy by obtaining spatially resolved spectra from objects at spatial resolutions varying from the level of single cells up to macroscopic objects (e.g. foods). In tandem with recent developments in instrumentation and sampling protocols, applications of HSI in microbiology have increased rapidly. This article gives a brief overview of the fundamentals of HSI and a comprehensive review of applications of HSI in microbiology over the past 10 years. Technical challenges and future perspectives for these techniques are also discussed.

  11. Molecular imaging: an overview and clinical applications.

    PubMed

    Rollo, F David

    2003-01-01

    Molecular imaging is a new medical discipline that integrates cell biology, molecular biology and diagnostic imaging. Clinical applications of molecular imaging include the use of nuclear medicine, magnetic resonance imaging (MRI) and ultrasound (US). The nuclear medicine applications utilize devices such as single photon emission computerized tomography (SPECT) and positron emission tomography (PET). Molecular imaging has two basic applications. The first is diagnostic imaging, which is used to determine the location and extent of targeted molecules specific to the disease being assessed. The second is therapy, which is used to treat specific disease-targeted molecules. The basic principle of the diagnostic imaging application is derived from the ability of cell and molecular biologists to identify specific receptor sites associated with target molecules that characterize the disease process to be studied. The biology teams then develop molecular imaging agents, which will bind specifically to the target molecules of interest. The principle for using molecular targeting therapy is based on an extension of the diagnostic imaging principle. Basically, it is assumed that if the molecular probe does target the specific disease molecules of interest, the same molecular agent can be loaded with an agent that will deliver therapy to the targeted cells. Patients and physicians have the clinical expectation that molecular imaging, when used for diagnostic purposes, will significantly improve the time-liness as well as the accuracy of detecting the presence and extent of disease. When applied to therapy, the expectation is that FDA-approved agents will have been shown in clinical trials to provide a significant improvement in clinical outcomes over traditional therapy methods. The eventual clinical owners of molecular imaging may be a specialty group that is a hybrid by conventional measures. For example, the clinical owner should have fundamental knowledge in basic

  12. Process for combining multiple passes of interferometric SAR data

    DOEpatents

    Bickel, Douglas L.; Yocky, David A.; Hensley, Jr., William H.

    2000-11-21

    Interferometric synthetic aperture radar (IFSAR) is a promising technology for a wide variety of military and civilian elevation modeling requirements. IFSAR extends traditional two dimensional SAR processing to three dimensions by utilizing the phase difference between two SAR images taken from different elevation positions to determine an angle of arrival for each pixel in the scene. This angle, together with the two-dimensional location information in the traditional SAR image, can be transformed into geographic coordinates if the position and motion parameters of the antennas are known accurately.

  13. Interferometric synthetic aperture radar studies of Alaska volcanoes

    USGS Publications Warehouse

    Lu, Zhiming; Wicks, C.; Power, J.; Dzurisin, D.; Thatcher, W.; Masterlark, Timothy

    2002-01-01

    Interferometric synthetic aperture radar (InSAR) imaging is a recently developed geodetic technique capable of measuring ground-surface deformation with centimeter to subcentimeter vertical precision and spatial resolution of tens-of-meter over a relatively large region (~104 km2). The spatial distribution of surface deformation data, derived from InSAR images, enables the construction of detailed mechanical models to enhance the study of magmatic and tectonic processes associated with volcanoes. This paper summarizes our recent InSAR studies of several Alaska volcanoes, which include Okmok, Akutan, Kiska, Augustine, Westdahl, and Peulik volcanoes.

  14. Rapid Development of Interferometric Software Using MIRIAD and Python

    NASA Astrophysics Data System (ADS)

    Williams, Peter K. G.; Law, Casey J.; Bower, Geoffrey C.

    2012-06-01

    State-of-the-art radio interferometers are complex systems that unleash torrents of data. If current and planned instruments are to routinely meet their performance goals, standard analysis techniques must be significantly improved, becoming simultaneously more sophisticated, more automatic, and more scalable. While there is no shortage of ideas for next-generation algorithms, there is a shortage of development resources, so it is vital that programming environments for interferometric software allow for rapid, flexible development. We present an open-source software package, miriad-python, that provides access to the MIRIAD interferometric reduction system in the Python programming language. The modular design of MIRIAD and the high productivity and accessibility of Python provide an excellent foundation for rapid development of interferometric software. Several other projects with similar goals exist, and we describe them and compare miriad-python with them in detail. Along with an overview of the package design, we present sample code and applications, including the detection of millisecond astrophysical transients, determination and application of nonstandard calibration parameters, interactive data visualization, and a reduction pipeline using a directed acyclic graph dependency model analogous to that of the traditional UNIX tool make. The key aspects of the miriad-python software project are documented. We find that miriad-python provides an extremely effective environment for prototyping new interferometric software, though certain existing packages provide far more infrastructure for some applications. While equivalent software written in compiled languages can be much faster than Python, there are many situations in which execution time is profitably exchanged for speed of development, code readability, accessibility to nonexpert programmers, quick interlinking with foreign software packages, and other virtues of the Python language.

  15. Solar Interferometric imaging from the Moon

    NASA Astrophysics Data System (ADS)

    Dame, L.; Martic, M.; Porteneuve, J.

    1994-06-01

    We present the concept of a Lunar Interferometer for Solar Physics. In particular we explain the rationale for a compact 2D array and we propose the use of a novel mechanical support structure based on linear mounting rods-these optimizing room and mass issues for transportation to the Moon.

  16. Genitourinary imaging: current and emerging applications.

    PubMed

    O' Donoghue, P M; McSweeney, S E; Jhaveri, K

    2010-01-01

    This review discusses the current and emerging techniques in urinary tract imaging. Recent technical advances and novel discoveries make this an exciting but challenging time for urinary tract imaging. The first section describes the imaging of the adrenal gland which has made great strides in the last decade, the current major adrenal imaging modalities as well as new applications are discussed with particular attention to the role of imaging in the incidentally detected adrenal lesion. In the second section the role of ultrasound, computed tomography (CT) and magnetic resonance (MR) in evaluation of the renal tract are discussed with the new technical advances leading to earlier detection and characterization of renal lesions. Complementary to this is the emerging role of CT and MR urography in assessment of the urinary tract and bladder in contrast to the demise of plain film studies/intravenous urography. The role of CT angiography in assessment of the renal vasculature is also discussed. The third section discusses the role of prostate imaging in the diagnosis, staging and management of prostate cancer. Transrectal ultrasonography, can be used to guide biopsy, CT is frequently used in staging, with bone scintigraphy and positron emission tomography having roles in advanced disease. Currently, all imaging modalities, especially MR are evolving to improve disease detection and staging. The final section discusses the recently encountered adverse reaction of nephrogenic systemic fibrosis in patients post gadolinium-enhanced MRI and how to help prevent this adverse reaction.

  17. Applications of Imaging Flow Cytometry for Microalgae.

    PubMed

    Hildebrand, Mark; Davis, Aubrey; Abbriano, Raffaela; Pugsley, Haley R; Traller, Jesse C; Smith, Sarah R; Shrestha, Roshan P; Cook, Orna; Sánchez-Alvarez, Eva L; Manandhar-Shrestha, Kalpana; Alderete, Benjamin

    2016-01-01

    The ability to image large numbers of cells at high resolution enhances flow cytometric analysis of cells and cell populations. In particular, the ability to image intracellular features adds a unique aspect to analyses, and can enable correlation between molecular phenomena resulting in alterations in cellular phenotype. Unicellular microalgae are amenable to high-throughput analysis to capture the diversity of cell types in natural samples, or diverse cellular responses in clonal populations, especially using imaging cytometry. Using examples from our laboratory, we review applications of imaging cytometry, specifically using an Amnis(®) ImageStream(®)X instrument, to characterize photosynthetic microalgae. Some of these examples highlight advantages of imaging flow cytometry for certain research objectives, but we also include examples that would not necessarily require imaging and could be performed on a conventional cytometer to demonstrate other concepts in cytometric evaluation of microalgae. We demonstrate the value of these approaches for (1) analysis of populations, (2) documentation of cellular features, and (3) analysis of gene expression. PMID:27460237

  18. Uncooled LWIR imaging: applications and market analysis

    NASA Astrophysics Data System (ADS)

    Takasawa, Satomi

    2015-05-01

    The evolution of infrared (IR) imaging sensor technology for defense market has played an important role in developing commercial market, as dual use of the technology has expanded. In particular, technologies of both reduction in pixel pitch and vacuum package have drastically evolved in the area of uncooled Long-Wave IR (LWIR; 8-14 μm wavelength region) imaging sensor, increasing opportunity to create new applications. From the macroscopic point of view, the uncooled LWIR imaging market is divided into two areas. One is a high-end market where uncooled LWIR imaging sensor with sensitivity as close to that of cooled one as possible is required, while the other is a low-end market which is promoted by miniaturization and reduction in price. Especially, in the latter case, approaches towards consumer market have recently appeared, such as applications of uncooled LWIR imaging sensors to night visions for automobiles and smart phones. The appearance of such a kind of commodity surely changes existing business models. Further technological innovation is necessary for creating consumer market, and there will be a room for other companies treating components and materials such as lens materials and getter materials and so on to enter into the consumer market.

  19. Iterated unscented Kalman filter for phase unwrapping of interferometric fringes.

    PubMed

    Xie, Xianming

    2016-08-22

    A fresh phase unwrapping algorithm based on iterated unscented Kalman filter is proposed to estimate unambiguous unwrapped phase of interferometric fringes. This method is the result of combining an iterated unscented Kalman filter with a robust phase gradient estimator based on amended matrix pencil model, and an efficient quality-guided strategy based on heap sort. The iterated unscented Kalman filter that is one of the most robust methods under the Bayesian theorem frame in non-linear signal processing so far, is applied to perform simultaneously noise suppression and phase unwrapping of interferometric fringes for the first time, which can simplify the complexity and the difficulty of pre-filtering procedure followed by phase unwrapping procedure, and even can remove the pre-filtering procedure. The robust phase gradient estimator is used to efficiently and accurately obtain phase gradient information from interferometric fringes, which is needed for the iterated unscented Kalman filtering phase unwrapping model. The efficient quality-guided strategy is able to ensure that the proposed method fast unwraps wrapped pixels along the path from the high-quality area to the low-quality area of wrapped phase images, which can greatly improve the efficiency of phase unwrapping. Results obtained from synthetic data and real data show that the proposed method can obtain better solutions with an acceptable time consumption, with respect to some of the most used algorithms. PMID:27557170

  20. Iterated unscented Kalman filter for phase unwrapping of interferometric fringes.

    PubMed

    Xie, Xianming

    2016-08-22

    A fresh phase unwrapping algorithm based on iterated unscented Kalman filter is proposed to estimate unambiguous unwrapped phase of interferometric fringes. This method is the result of combining an iterated unscented Kalman filter with a robust phase gradient estimator based on amended matrix pencil model, and an efficient quality-guided strategy based on heap sort. The iterated unscented Kalman filter that is one of the most robust methods under the Bayesian theorem frame in non-linear signal processing so far, is applied to perform simultaneously noise suppression and phase unwrapping of interferometric fringes for the first time, which can simplify the complexity and the difficulty of pre-filtering procedure followed by phase unwrapping procedure, and even can remove the pre-filtering procedure. The robust phase gradient estimator is used to efficiently and accurately obtain phase gradient information from interferometric fringes, which is needed for the iterated unscented Kalman filtering phase unwrapping model. The efficient quality-guided strategy is able to ensure that the proposed method fast unwraps wrapped pixels along the path from the high-quality area to the low-quality area of wrapped phase images, which can greatly improve the efficiency of phase unwrapping. Results obtained from synthetic data and real data show that the proposed method can obtain better solutions with an acceptable time consumption, with respect to some of the most used algorithms.

  1. Applications Of Binary Image Analysis Techniques

    NASA Astrophysics Data System (ADS)

    Tropf, H.; Enderle, E.; Kammerer, H. P.

    1983-10-01

    After discussing the conditions where binary image analysis techniques can be used, three new applications of the fast binary image analysis system S.A.M. (Sensorsystem for Automation and Measurement) are reported: (1) The human view direction is measured at TV frame rate while the subject's head is free movable. (2) Industrial parts hanging on a moving conveyor are classified prior to spray painting by robot. (3) In automotive wheel assembly, the eccentricity of the wheel is minimized by turning the tyre relative to the rim in order to balance the eccentricity of the components.

  2. Acquisition and applications of 3D images

    NASA Astrophysics Data System (ADS)

    Sterian, Paul; Mocanu, Elena

    2007-08-01

    The moiré fringes method and their analysis up to medical and entertainment applications are discussed in this paper. We describe the procedure of capturing 3D images with an Inspeck Camera that is a real-time 3D shape acquisition system based on structured light techniques. The method is a high-resolution one. After processing the images, using computer, we can use the data for creating laser fashionable objects by engraving them with a Q-switched Nd:YAG. In medical field we mention the plastic surgery and the replacement of X-Ray especially in pediatric use.

  3. Extended SWIR imaging sensors for hyperspectral imaging applications

    NASA Astrophysics Data System (ADS)

    Weber, A.; Benecke, M.; Wendler, J.; Sieck, A.; Hübner, D.; Figgemeier, H.; Breiter, R.

    2016-05-01

    AIM has developed SWIR modules including FPAs based on liquid phase epitaxy (LPE) grown MCT usable in a wide range of hyperspectral imaging applications. Silicon read-out integrated circuits (ROIC) provide various integration and readout modes including specific functions for spectral imaging applications. An important advantage of MCT based detectors is the tunable band gap. The spectral sensitivity of MCT detectors can be engineered to cover the extended SWIR spectral region up to 2.5μm without compromising in performance. AIM developed the technology to extend the spectral sensitivity of its SWIR modules also into the VIS. This has been successfully demonstrated for 384x288 and 1024x256 FPAs with 24μm pitch. Results are presented in this paper. The FPAs are integrated into compact dewar cooler configurations using different types of coolers, like rotary coolers, AIM's long life split linear cooler MCC030 or extreme long life SF100 Pulse Tube cooler. The SWIR modules include command and control electronics (CCE) which allow easy interfacing using a digital standard interface. The development status and performance results of AIM's latest MCT SWIR modules suitable for hyperspectral systems and applications will be presented.

  4. Interferometric smart material for measuring permanent deformations

    SciTech Connect

    Li, K.

    1996-05-01

    This paper has presented a novel interferometric smart material using closely spaced micro-indentations as sensors for recording permanent deformations. The information can be retrieved from the interference fringe patterns of laser light reflected and diffracted from the ISM indentations. Practically, the interference fringes are monitored with linear photodiode arrays in conjunction with a microcomputer based digital data acquisition system. The measurement can be conducted at any convenient time and needs not conflict with in-situ operations. Validity and accuracy of the method have been confirmed by the comparison with standard measurements. The ISM acts like a smart material to memorize permanent deformations. Different from the ISG and ISR real-time measuring techniques, the ISM measurement may be performed at any convenient time, and large deformations can be measured. The ISM method competes with other optical methods for its extremely compact sensors and applicability to production environments. It measures the indentation separations through analyzing the interference fringe patterns and has a better accuracy than a microscope. It is applicable to curved surfaces and notched regions in large structures.

  5. Airborne Radar Interferometric Repeat-Pass Processing

    NASA Technical Reports Server (NTRS)

    Hensley, Scott; Michel, Thierry R.; Jones, Cathleen E.; Muellerschoen, Ronald J.; Chapman, Bruce D.; Fore, Alexander; Simard, Marc; Zebker, Howard A.

    2011-01-01

    Earth science research often requires crustal deformation measurements at a variety of time scales, from seconds to decades. Although satellites have been used for repeat-track interferometric (RTI) synthetic-aperture-radar (SAR) mapping for close to 20 years, RTI is much more difficult to implement from an airborne platform owing to the irregular trajectory of the aircraft compared with microwave imaging radar wavelengths. Two basic requirements for robust airborne repeat-pass radar interferometry include the ability to fly the platform to a desired trajectory within a narrow tube and the ability to have the radar beam pointed in a desired direction to a fraction of a beam width. Uninhabited Aerial Vehicle Synthetic Aperture Radar (UAVSAR) is equipped with a precision auto pilot developed by NASA Dryden that allows the platform, a Gulfstream III, to nominally fly within a 5 m diameter tube and with an electronically scanned antenna to position the radar beam to a fraction of a beam width based on INU (inertial navigation unit) attitude angle measurements.

  6. Multifunctional Magnetic Nanoparticles for Medical Imaging Applications

    PubMed Central

    Fang, Chen; Zhang, Miqin

    2010-01-01

    Magnetic nanoparticles (MNPs) have attracted enormous research attention due to their unique magnetic properties that enable the detection by the non-invasive medical imaging modality—magnetic resonance imaging (MRI). By incorporating advanced features, such as specific targeting, multimodality, therapeutic delivery, the detectability and applicability of MNPs have been dramatically expanded. A delicate design on structure, composition and surface chemistry is essential to achieving desired properties in MNP systems, such as high imaging contrast and chemical stability, non-fouling surface, target specificity and/or multimodality. This article presents the design fundamentals on the development of MNP systems, from discussion of material selection for nanoparticle cores and coatings, strategies for chemical synthesis and surface modification and their merits and limitations, to conjugation of special biomolecules for intended functions, and reviews the recent advances in the field. PMID:20593005

  7. Active gated imaging for automotive safety applications

    NASA Astrophysics Data System (ADS)

    Grauer, Yoav; Sonn, Ezri

    2015-03-01

    The paper presents the Active Gated Imaging System (AGIS), in relation to the automotive field. AGIS is based on a fast gated-camera equipped with a unique Gated-CMOS sensor, and a pulsed Illuminator, synchronized in the time domain to record images of a certain range of interest which are then processed by computer vision real-time algorithms. In recent years we have learned the system parameters which are most beneficial to night-time driving in terms of; field of view, illumination profile, resolution and processing power. AGIS provides also day-time imaging with additional capabilities, which enhances computer vision safety applications. AGIS provides an excellent candidate for camera-based Advanced Driver Assistance Systems (ADAS) and the path for autonomous driving, in the future, based on its outstanding low/high light-level, harsh weather conditions capabilities and 3D potential growth capabilities.

  8. Biomedical Applications of Terahertz Spectroscopy and Imaging.

    PubMed

    Yang, Xiang; Zhao, Xiang; Yang, Ke; Liu, Yueping; Liu, Yu; Fu, Weiling; Luo, Yang

    2016-10-01

    Terahertz (THz=10(12)Hz) radiation has attracted wide attention for its unprecedented sensing ability and its noninvasive and nonionizing properties. Tremendous strides in THz instrumentation have prompted impressive breakthroughs in THz biomedical research. Here, we review the current state of THz spectroscopy and imaging in various biomedical applications ranging from biomolecules, including DNA/RNA, amino acids/peptides, proteins, and carbohydrates, to cells and tissues. We also address the potential biological effects of THz radiation during its biological applications and propose future prospects for this cutting-edge technology.

  9. Whole body MR imaging: applications in oncology.

    PubMed

    Johnston, C; Brennan, S; Ford, S; Eustace, S

    2006-04-01

    This article reviews technique and clinical applications of whole body MR imaging as a diagnostic tool in cancer staging. In particular the article reviews its role as an alternative to scintigraphy (bone scan and PET) in staging skeletal spread of disease, its role in assessing total tumour burden, its role in multiple myeloma and finally its evolving non oncologic role predominantly assessing total body composition.

  10. Adaptive optics retinal imaging: emerging clinical applications.

    PubMed

    Godara, Pooja; Dubis, Adam M; Roorda, Austin; Duncan, Jacque L; Carroll, Joseph

    2010-12-01

    The human retina is a uniquely accessible tissue. Tools like scanning laser ophthalmoscopy and spectral domain-optical coherence tomography provide clinicians with remarkably clear pictures of the living retina. Although the anterior optics of the eye permit such non-invasive visualization of the retina and associated pathology, the same optics induce significant aberrations that obviate cellular-resolution imaging in most cases. Adaptive optics (AO) imaging systems use active optical elements to compensate for aberrations in the optical path between the object and the camera. When applied to the human eye, AO allows direct visualization of individual rod and cone photoreceptor cells, retinal pigment epithelium cells, and white blood cells. AO imaging has changed the way vision scientists and ophthalmologists see the retina, helping to clarify our understanding of retinal structure, function, and the etiology of various retinal pathologies. Here, we review some of the advances that were made possible with AO imaging of the human retina and discuss applications and future prospects for clinical imaging.

  11. Target identification and navigation performance modeling of a passive millimeter wave imager.

    PubMed

    Jacobs, Eddie L; Furxhi, Orges

    2010-07-01

    Human task performance using a passive interferometric millimeter wave imaging sensor is modeled using a task performance modeling approach developed by the U.S. Army Night Vision and Electronic Sensors Directorate. The techniques used are illustrated for an imaging system composed of an interferometric antenna array, optical upconversion, and image formation using a shortwave infrared focal plane array. Two tasks, target identification and pilotage, are modeled. The effects of sparse antenna arrays on task performance are considered. Applications of this model include system trade studies for concealed weapon identification, navigation in fog, and brownout conditions. PMID:20648126

  12. Target identification and navigation performance modeling of a passive millimeter wave imager.

    PubMed

    Jacobs, Eddie L; Furxhi, Orges

    2010-07-01

    Human task performance using a passive interferometric millimeter wave imaging sensor is modeled using a task performance modeling approach developed by the U.S. Army Night Vision and Electronic Sensors Directorate. The techniques used are illustrated for an imaging system composed of an interferometric antenna array, optical upconversion, and image formation using a shortwave infrared focal plane array. Two tasks, target identification and pilotage, are modeled. The effects of sparse antenna arrays on task performance are considered. Applications of this model include system trade studies for concealed weapon identification, navigation in fog, and brownout conditions.

  13. Applications review for a Space Program Imaging Radar (SPIR)

    NASA Technical Reports Server (NTRS)

    Simonett, D. S.

    1976-01-01

    The needs, applications, user support, research, and theoretical studies of imaging radar are reviewed. The applications of radar in water resources, minerals and petroleum exploration, vegetation resources, ocean radar imaging, and cartography are discussed. The advantages of space imaging radar are presented, and it is recommended that imaging radar be placed on the space shuttle.

  14. Photonic crystal fiber interferometric vector bending sensor.

    PubMed

    Villatoro, Joel; Minkovich, Vladimir P; Zubia, Joseba

    2015-07-01

    A compact and highly sensitive interferometric bending sensor (inclinometer) capable of distinguishing the bending or inclination orientation is demonstrated. The device operates in reflection mode and consists of a short segment of photonic crystal fiber (PCF) inserted in conventional single-mode optical fiber (SMF). A microscopic collapsed zone in the PCF-SMF junction allows the excitation and recombination of core modes, hence, to build a mode interferometer. Bending on the device induces asymmetric refractive index changes in the PCF core as well as losses. As a result, the effective indices and intensities of the interfering modes are altered, which makes the interference pattern shift and shrink. The asymmetric index changes in the PCF make our device capable of distinguishing the bending orientation. The sensitivity of our sensor is up to 1225 pm/degree and it can be used to monitor small bending angles (±2°). We believe that the attributes of our sensor make it appealing in a number of applications. PMID:26125380

  15. Image Understanding Applications of Lattice Autoassociative Memories.

    PubMed

    Grana, Manuel; Chyzhyk, Darya

    2016-09-01

    Multivariate mathematical morphology (MMM) aims to extend the mathematical morphology from gray scale images to images whose pixels are high-dimensional vectors, such as remote sensing hyperspectral images and functional magnetic resonance images (fMRIs). Defining an ordering over the multidimensional image data space is a fundamental issue MMM, to ensure that ensuing morphological operators and filters are mathematically consistent. Recent approaches use the outputs of two-class classifiers to build such reduced orderings. This paper presents the applications of MMM built on reduced supervised orderings based on lattice autoassociative memories (LAAMs) recall error measured by the Chebyshev distance. Foreground supervised orderings use one set of training data from a foreground class, whereas background/foreground supervised orderings use two training data sets, one for each relevant class. The first case study refers to the realization of the thematic segmentation of the hyperspectral images using spatial-spectral information. Spectral classification is enhanced by a spatial processing consisting in the spatial correction guided by a watershed segmentation computed by the LAAM-based morphological operators. The approach improves the state-of-the-art hyperspectral spatial-spectral thematic map building approaches. The second case study is the analysis of resting state fMRI data, working on a data set of healthy controls, schizophrenia patients with and without auditory hallucinations. We perform two experiments: 1) the localization of differences in brain functional networks on population-dependent templates and 2) the classification of subjects into each possible pair of cases. In this data set, we find that the LAAM-based morphological features improve over the conventional correlation-based graph measure features often employed in fMRI data classification.

  16. Image Understanding Applications of Lattice Autoassociative Memories.

    PubMed

    Grana, Manuel; Chyzhyk, Darya

    2016-09-01

    Multivariate mathematical morphology (MMM) aims to extend the mathematical morphology from gray scale images to images whose pixels are high-dimensional vectors, such as remote sensing hyperspectral images and functional magnetic resonance images (fMRIs). Defining an ordering over the multidimensional image data space is a fundamental issue MMM, to ensure that ensuing morphological operators and filters are mathematically consistent. Recent approaches use the outputs of two-class classifiers to build such reduced orderings. This paper presents the applications of MMM built on reduced supervised orderings based on lattice autoassociative memories (LAAMs) recall error measured by the Chebyshev distance. Foreground supervised orderings use one set of training data from a foreground class, whereas background/foreground supervised orderings use two training data sets, one for each relevant class. The first case study refers to the realization of the thematic segmentation of the hyperspectral images using spatial-spectral information. Spectral classification is enhanced by a spatial processing consisting in the spatial correction guided by a watershed segmentation computed by the LAAM-based morphological operators. The approach improves the state-of-the-art hyperspectral spatial-spectral thematic map building approaches. The second case study is the analysis of resting state fMRI data, working on a data set of healthy controls, schizophrenia patients with and without auditory hallucinations. We perform two experiments: 1) the localization of differences in brain functional networks on population-dependent templates and 2) the classification of subjects into each possible pair of cases. In this data set, we find that the LAAM-based morphological features improve over the conventional correlation-based graph measure features often employed in fMRI data classification. PMID:26292345

  17. Overview and Applications of UAVSAR's Multi-Squint Polarimetric Imaging Mode

    NASA Technical Reports Server (NTRS)

    Scott Hensley; Chen, Curtis; Michel, Thierry; Jones, Cathleen; Chapman, Bruce; Muellerschoen, Ron

    2011-01-01

    NASA's Jet Propulsion Laboratory has developed a reconfigurable polarimetric L-band synthetic aperture radar (SAR), specifically designed to acquire airborne repeat track interferometric (RTI) SAR data for application to monitoring surface deformation and vegetation structure measurements. The system employs a precision autopilot developed by NASA Dryden that allows the plane to fly precise trajectories usually within a 5 m tube. Also required for robust repeat pass applications is the ability to point the antenna in the same direction on repeat passes to a fraction of an azimuth beamwidth (8? for UAVSAR). This precise pointing is achieved using an electronically scanned antenna whose pointing is based on inertial navigation unit (INU) attitude angle data. The radar design is fully polarimetric with an 80 MHz bandwidth (2 m range resolution) and has a greater than 20 km range swath when flying at its nominal altitude of 12500 m. The ability to electronically steer the beam on a pulse-to-pulse basis has allowed a new mode of SAR data acquisition whereby the radar beam is steered to different squint angles on successive pulses thereby simultaneously generating images at multiple squint angles. This mode offers the possibility of generating vector deformation measurements with a single pair of repeat passes and to obtain greater kz diversity for vegetation studies with a reduced number of passes. This paper will present an overview of the mode, discuss its potential for deformation and vegetation, and show some examples using UAVSAR data.

  18. Applications of scientific imaging in environmental toxicology

    NASA Astrophysics Data System (ADS)

    El-Demerdash, Aref M.

    The national goals of clean air, clean water, and healthy ecosystems are a few of the primary forces that drive the need for better environmental monitoring. As we approach the end of the 1990s, the environmental questions at regional to global scales are being redefined and refined in the light of developments in environmental understanding and technological capability. Research in the use of scientific imaging data for the study of the environment is urgently needed in order to explore the possibilities of utilizing emerging new technologies. The objective of this research proposal is to demonstrate the usability of a wealth of new technology made available in the last decade to providing a better understanding of environmental problems. Research is focused in two imaging techniques macro and micro imaging. Several examples of applications of scientific imaging in research in the field of environmental toxicology were presented. This was achieved on two scales, micro and macro imaging. On the micro level four specific examples were covered. First, the effect of utilizing scanning electron microscopy as an imaging tool in enhancing taxa identification when studying diatoms was presented. Second, scanning electron microscopy combined with energy dispersive x-ray analyzer were demonstrated as a valuable and effective tool for identifying and analyzing household dust samples. Third, electronic autoradiography combined with FT-IR microscopy were used to study the distribution pattern of [14C]-Malathion in rats as a result of dermal exposure. The results of the autoradiography made on skin sections of the application site revealed the presence of [ 14C]-activity in the first region of the skin. These results were evidenced by FT-IR microscopy. The obtained results suggest that the penetration of Malathion into the skin and other tissues is vehicle and dose dependent. The results also suggest the use of FT-IR microscopy imaging for monitoring the disposition of

  19. Nanoporous alumina-based interferometric transducers ennobled

    NASA Astrophysics Data System (ADS)

    Dronov, Roman; Jane, Andrew; Shapter, Joseph G.; Hodges, Alastair; Voelcker, Nicolas H.

    2011-08-01

    A high fidelity interferometric transducer is designed based on platinum-coated nanoporous alumina films. The ultrathin metal coating significantly improves fidelity of the interferometric fringe patterns in aqueous solution and increases the signal-to-noise ratio. The performance of this transducer is tested with respect to refractive index unit (RIU) sensitivity measured as a change in effective optical thickness (EOT) in response to a solvent change and compared to porous silicon based transducers. RIU sensitivity in the order of 55% is attainable for porous alumina providing excellent signal-to-noise ratio, which exceeds the sensitivity of current interferometric transducers. Finally, as a proof-of-principle, we demonstrate biosensing with two distinct immunoglobulin antibodies.A high fidelity interferometric transducer is designed based on platinum-coated nanoporous alumina films. The ultrathin metal coating significantly improves fidelity of the interferometric fringe patterns in aqueous solution and increases the signal-to-noise ratio. The performance of this transducer is tested with respect to refractive index unit (RIU) sensitivity measured as a change in effective optical thickness (EOT) in response to a solvent change and compared to porous silicon based transducers. RIU sensitivity in the order of 55% is attainable for porous alumina providing excellent signal-to-noise ratio, which exceeds the sensitivity of current interferometric transducers. Finally, as a proof-of-principle, we demonstrate biosensing with two distinct immunoglobulin antibodies. Electronic supplementary information (ESI) available: EOT sensorgram of adsorption of BSA and normal human IgG onto hydroxylated porous alumina, FWHM of interferometric spectra, and theoretical comparison of calculated RIU sensitivities for 1 µm thick porous alumina and porous silicon films. See DOI: 10.1039/c0nr00897d

  20. The application of ghost imaging in infrared imaging detection technology

    NASA Astrophysics Data System (ADS)

    Peng, Hongtao; Yang, Zhaohua; Li, Dapeng; Wu, Ling-an

    2015-11-01

    Traditional imaging are mostly based on the principle of lens imaging which is simple but the imaging result is heavily dependent on the quality of detector. It is usual to increase the detector array density or reduce the size of pixels to improve the imaging resolution, especially for infrared imaging. It will decrease the light flux causing the noise enhance relatively and add the cost on the contrary. Besides, there is a novel imaging technology called ghost imaging. We present a new infrared imaging method named computational ghost imaging only using a bucket detector without spatial resolution, which avoiding the allocation of flux on the pixel dimension as well as reducing the cost.

  1. Application of GFP imaging in cancer.

    PubMed

    Hoffman, Robert M

    2015-04-01

    Multicolored proteins have allowed the color-coding of cancer cells growing in vivo and enabled the distinction of host from tumor with single-cell resolution. Non-invasive imaging with fluorescent proteins enabled the dynamics of metastatic cancer to be followed in real time in individual animals. Non-invasive imaging of cancer cells expressing fluorescent proteins has allowed the real-time determination of efficacy of candidate antitumor and antimetastatic agents in mouse models. The use of fluorescent proteins to differentially label cancer cells in the nucleus and cytoplasm can visualize the nuclear-cytoplasmic dynamics of cancer cells in vivo including: mitosis, apoptosis, cell-cycle position, and differential behavior of nucleus and cytoplasm that occurs during cancer-cell deformation and extravasation. Recent applications of the technology described here include linking fluorescent proteins with cell-cycle-specific proteins such that the cells change color from red to green as they transit from G1 to S phases. With the macro- and micro-imaging technologies described here, essentially any in vivo process can be imaged, giving rise to the new field of in vivo cell biology using fluorescent proteins.

  2. Application of GFP imaging in cancer.

    PubMed

    Hoffman, Robert M

    2015-04-01

    Multicolored proteins have allowed the color-coding of cancer cells growing in vivo and enabled the distinction of host from tumor with single-cell resolution. Non-invasive imaging with fluorescent proteins enabled the dynamics of metastatic cancer to be followed in real time in individual animals. Non-invasive imaging of cancer cells expressing fluorescent proteins has allowed the real-time determination of efficacy of candidate antitumor and antimetastatic agents in mouse models. The use of fluorescent proteins to differentially label cancer cells in the nucleus and cytoplasm can visualize the nuclear-cytoplasmic dynamics of cancer cells in vivo including: mitosis, apoptosis, cell-cycle position, and differential behavior of nucleus and cytoplasm that occurs during cancer-cell deformation and extravasation. Recent applications of the technology described here include linking fluorescent proteins with cell-cycle-specific proteins such that the cells change color from red to green as they transit from G1 to S phases. With the macro- and micro-imaging technologies described here, essentially any in vivo process can be imaged, giving rise to the new field of in vivo cell biology using fluorescent proteins. PMID:25686095

  3. Diffusion weighted imaging: Technique and applications

    PubMed Central

    Baliyan, Vinit; Das, Chandan J; Sharma, Raju; Gupta, Arun Kumar

    2016-01-01

    Diffusion weighted imaging (DWI) is a method of signal contrast generation based on the differences in Brownian motion. DWI is a method to evaluate the molecular function and micro-architecture of the human body. DWI signal contrast can be quantified by apparent diffusion coefficient maps and it acts as a tool for treatment response evaluation and assessment of disease progression. Ability to detect and quantify the anisotropy of diffusion leads to a new paradigm called diffusion tensor imaging (DTI). DTI is a tool for assessment of the organs with highly organised fibre structure. DWI forms an integral part of modern state-of-art magnetic resonance imaging and is indispensable in neuroimaging and oncology. DWI is a field that has been undergoing rapid technical evolution and its applications are increasing every day. This review article provides insights in to the evolution of DWI as a new imaging paradigm and provides a summary of current role of DWI in various disease processes. PMID:27721941

  4. SOURCE DETECTION IN INTERFEROMETRIC VISIBILITY DATA. I. FUNDAMENTAL ESTIMATION LIMITS

    SciTech Connect

    Trott, Cathryn M.; Wayth, Randall B.; Macquart, Jean-Pierre R.; Tingay, Steven J.

    2011-04-20

    Transient radio signals of astrophysical origin present an avenue for studying the dynamic universe. With the next generation of radio interferometers being planned and built, there is great potential for detecting and studying large samples of radio transients. Currently used image-based techniques for detecting radio sources have not been demonstrated to be optimal, and there is a need for development of more sophisticated algorithms and methodology for comparing different detection techniques. A visibility-space detector benefits from our good understanding of visibility-space noise properties and does not suffer from the image artifacts and need for deconvolution in image-space detectors. In this paper, we propose a method for designing optimal source detectors using visibility data, building on statistical decision theory. The approach is substantially different to conventional radio astronomy source detection. Optimal detection requires an accurate model for the data, and we present a realistic model for the likelihood function of radio interferometric data, including the effects of calibration, signal confusion, and atmospheric phase fluctuations. As part of this process, we derive fundamental limits on the calibration of an interferometric array, including the case where many relatively weak 'in-beam' calibrators are used. These limits are then applied, along with a model for atmospheric phase fluctuations, to determine the limits on measuring source position, flux density, and spectral index, in the general case. We then present an optimal visibility-space detector using realistic models for an interferometer.

  5. Interferometric Rayleigh Scattering Measurement System

    NASA Technical Reports Server (NTRS)

    Bivolaru, Daniel (Inventor); Danehy, Paul M. (Inventor); Lee, Joseph W. (Inventor)

    2008-01-01

    A method and apparatus for performing simultaneous multi-point measurements of multiple velocity components in a gas flow is described. Pulses of laser light are directed to a measurement region of unseeded gas to produce Rayleigh or Mie scattered light in a plurality of directions. The Rayleigh or Mie scattered light is collected from multiple directions and combined in a single collimated light beam. The Rayleigh or Mie scattered light is then mixed together with a reference laser light before it is passed through a single planar Fabry-Perot interferometer for spectral analysis. At the output of the interferometer, a high-sensitivity CCD camera images the interference fringe pattern. This pattern contains the spectral and spatial information from both the Rayleigh scattered light and the reference laser light. Interferogram processing software extracts and analyzes spectral profiles to determine the velocity components of the gas flow at multiple points in the measurement region. The Rayleigh light rejected by the interferometer is recirculated to increase the accuracy and the applicability of the method for measurements at high temperatures without requiring an increase in the laser energy.

  6. Interferometric, astrometric, and photometric studies of Epsilon Aurigae: Seeing the disk around a distant star

    NASA Astrophysics Data System (ADS)

    Kloppenborg, Brian

    2012-05-01

    Epsilon (epsilon) Aurigae is a binary star system that has baffled astronomers for 170 years. In 1821 it was first noticed that the star system had dimmed by nearly 50%. After many decades of photometric monitoring, the 27.1 year period was finally established in 1903. A few years later, in 1912, Henry Norris Russell published the first analytic methods for binary star analysis. Later application of these formulae came to an interesting conclusion; the system was composed of two stars: the visible F-type supergiant, and an equally massive, but yet photometrically and spectroscopically invisible, companion. Several theories were advanced to explain this low-light to high-mass conundrum, eventually settling on the notion that the companion object is obscured from view by a disk of opaque material. With this topic solved, the debate shifted the evolutionary state of the system. Two scenarios became dominant: the system is either relativity young, and composed of a massive, 15 Mo (solar mass), F-type supergiant and a nearly equally massive main sequence companion inside of the disk; or a much older and significantly less massive, 4 Mo, F-type post-asymptotic giant branch object with a more massive, 6 Mo, companion surrounded by a debris disk. In this dissertation I disentangle the two evolutionary states by comparing the photometric behavior of the F-type star to known supergiant and post-asymptotic giant branch objects; and deriving a dynamical mass for the two components using astrometric, radial velocity, and interferometric data. Along with this, I provide the first interferometric images during the eclipse which prove the 50% dimming is indeed caused by an opaque disk. The first chapter presents the reader with the status quo of epsilon Aurigae research and the topics I wish to address in this dissertation. Chapter two presents an analysis of nearly 30 years of photometry on the system, concluding the star periodically exhibits stable pulsation on 1/3 orbital

  7. Resolving phase ambiguities in the calibration of redundant interferometric arrays: implications for array design

    NASA Astrophysics Data System (ADS)

    Kurien, Binoy G.; Tarokh, Vahid; Rachlin, Yaron; Shah, Vinay N.; Ashcom, Jonathan B.

    2016-10-01

    We provide new results enabling robust interferometric image reconstruction in the presence of unknown aperture piston variation via the technique of redundant spacing calibration (RSC). The RSC technique uses redundant measurements of the same interferometric baseline with different pairs of apertures to reveal the piston variation among these pairs. In both optical and radio interferometry, the presence of phase-wrapping ambiguities in the measurements is a fundamental issue that needs to be addressed for reliable image reconstruction. In this paper, we show that these ambiguities affect recently developed RSC phasor-based reconstruction approaches operating on the complex visibilities, as well as traditional phase-based approaches operating on their logarithm. We also derive new sufficient conditions for an interferometric array to be immune to these ambiguities in the sense that their effect can be rendered benign in image reconstruction. This property, which we call wrap-invariance, has implications for the reliability of imaging via classical three-baseline phase closures as well as generalized closures. We show that wrap-invariance is conferred upon arrays whose interferometric graph satisfies a certain cycle-free condition. For cases in which this condition is not satisfied, a simple algorithm is provided for identifying those graph cycles which prevent its satisfaction. We apply this algorithm to diagnose and correct a member of a pattern family popular in the literature.

  8. Modifications of intensity-interferometric spectral-domain optical coherence tomography with dispersion cancellation

    NASA Astrophysics Data System (ADS)

    Shirai, Tomohiro

    2015-04-01

    Intensity-interferometric spectral-domain (SD) optical coherence tomography (OCT) developed recently enables axial-scan-free cross-sectional imaging with group-velocity dispersion cancellation and a factor-of-\\sqrt{2} resolution improvement. This paper is concerned with a simple and practical method of realizing OCT of this kind. Specifically, we demonstrate theoretically and experimentally that intensity-interferometric SD-OCT can be realized in a simple way by means of a slightly modified conventional SD-OCT setup.

  9. Measurement of inhomogeneous absorptive organic media with polarization interferometric confocal microscope

    NASA Astrophysics Data System (ADS)

    Fujita, Kohei; Egami, Chikara

    2015-06-01

    Polarization interferometric confocal microscope has been developed for high-precision measurement, especially for inhomogeneous organic media doped with nonlinear chromophores. The microscope has a novel contrast-enhancing technique: suppressing the background electric field with polarization interferometer. With this technique, the microscope has allowed optical anisotropy detection in a submicron area (400 nm × 400 nm), even with a low-cost and low-power continuous-wave (CW) laser light source. In particular, the microscope clearly distinguishes between isotropic and anisotropic regions. According to polarization interferometric ellipsometry, the microscope produces inspection images showing planer distribution of the optical parameter directly.

  10. Observing the Sun with micro-interferometric devices: a didactic experiment

    NASA Astrophysics Data System (ADS)

    Defrère, D.; Absil, O.; Hanot, C.; Riaud, P.; Magette, A.; Marion, L.; Wertz, O.; Finet, F.; Steenackers, M.; Habraken, S.; Surdej, A.; Surdej, J.

    2014-04-01

    Measuring the angular diameter of celestial bodies has long been the main purpose of stellar interferometry and was its historical motivation. Nowadays, stellar interferometry is widely used for various other scientific purposes that require very high angular resolution measurements. In terms of angular spatial scales probed, observing distant stars located 10 to 100~pc away with a large hectometric interferometer is equivalent to observing our Sun with a micrometric baseline. Based on this idea, we have manufactured a set of micro-interferometric devices and tested them on the sky. The micro-interferometers consist of a chrome layer deposited on a glass plate that has been drilled by laser lithography to produce micron-sized holes with configurations corresponding to proposed interferometer projects such as CARLINA, ELSA, KEOPS, and OVLA. In this paper, we describe these interferometric devices and present interferometric observations of the Sun made in the framework of Astrophysics lectures being taught at the Liège University. By means of a simple photographic camera placed behind a micro-interferometric device, we observed the Sun and derived its angular size. This experiment provides a very didactic way to easily obtain fringe patterns similar to those that will be obtained with future large imaging arrays. A program written in C also allows to reproduce the various point spread functions and fringe patterns observed with the micro-interferometric devices for different types of sources, including the Sun.

  11. Mutual interferometric characterization of a pair of independent electric fields.

    PubMed

    Bourassin-Bouchet, Charles; Mang, Matthias M; Gianani, Ilaria; Walmsley, Ian A

    2013-12-15

    We demonstrate a novel interferometric characterization scheme that allows the complete reconstruction of two interfering electric fields. The phase profiles of both beams, and their relative phase, can be retrieved simultaneously as a function of any degree of freedom in which it is possible to shear one of the beams. The method has applications in wavefront sensing or ultrashort-pulse measurement, especially also in the domain of extreme light sources where it is difficult to generate a reference field or to replicate the beam in order to perform a self-referencing measurement. We demonstrate the technique experimentally by measuring simultaneously two ultrashort pulses in a single laser shot. PMID:24322242

  12. Satellite emission radio interferometric earth surveying series - GPS geodetic system

    NASA Technical Reports Server (NTRS)

    Macdoran, P. F.

    1979-01-01

    A concept called SERIES (satellite emissions radio interferometric earth surveying) which makes use of GPS (global positioning system) radio transmissions without any satellite modifications, is described. Through the use of very long baseline interferometry (VLBI) and its calibration methods, 0.5 to 3 cm three dimensional baseline accuracy can be achieved over distances of 2 to 200 km respectively, with only 2 hours of on-site data acquisition. Attention is given to such areas as: the radio flux equivalent of GPS transmissions, synthesized delay precision, transmission and frequency subsystem requirements, tropospheric and ionospheric errors. Applications covered include geodesy and seismic tectonics.

  13. Broadband infrared beam splitter for spaceborne interferometric infrared sounder.

    PubMed

    Yu, Tianyan; Liu, Dingquan; Qin, Yang

    2014-10-01

    A broadband infrared beam splitter (BS) on ZnSe substrate used for the spaceborne interferometric infrared sounder (SIIRS) is studied in the spectral range of 4.44-15 μm. Both broadband antireflection coating and broadband beam-splitter coating in this BS are designed and tested. To optimize the optical properties and the stability of the BS, suitable infrared materials were selected, and improved deposition techniques were applied. The designed structures matched experimental data well, and the properties of the BS met the application specification of SIIRS. PMID:25322240

  14. Three-dimensional motion correction using speckle and phase for in vivo computed optical interferometric tomography

    PubMed Central

    Shemonski, Nathan D.; Ahn, Shawn S.; Liu, Yuan-Zhi; South, Fredrick A.; Carney, P. Scott; Boppart, Stephen A.

    2014-01-01

    Over the years, many computed optical interferometric techniques have been developed to perform high-resolution volumetric tomography. By utilizing the phase and amplitude information provided with interferometric detection, post-acquisition corrections for defocus and optical aberrations can be performed. The introduction of the phase, though, can dramatically increase the sensitivity to motion (most prominently along the optical axis). In this paper, we present two algorithms which, together, can correct for motion in all three dimensions with enough accuracy for defocus and aberration correction in computed optical interferometric tomography. The first algorithm utilizes phase differences within the acquired data to correct for motion along the optical axis. The second algorithm utilizes the addition of a speckle tracking system using temporally- and spatially-coherent illumination to measure motion orthogonal to the optical axis. The use of coherent illumination allows for high-contrast speckle patterns even when imaging apparently uniform samples or when highly aberrated beams cannot be avoided. PMID:25574426

  15. Robust image modeling techniques with an image restoration application

    NASA Astrophysics Data System (ADS)

    Kashyap, Rangasami L.; Eom, Kie-Bum

    1988-08-01

    A robust parameter-estimation algorithm for a nonsymmetric half-plane (NSHP) autoregressive model, where the driving noise is a mixture of a Gaussian and an outlier process, is presented. The convergence of the estimation algorithm is proved. An algorithm to estimate parameters and original image intensity simultaneously from the impulse-noise-corrupted image, where the model governing the image is not available, is also presented. The robustness of the parameter estimates is demonstrated by simulation. Finally, an algorithm to restore realistic images is presented. The entire image generally does not obey a simple image model, but a small portion (e.g., 8 x 8) of the image is assumed to obey an NSHP model. The original image is divided into windows and the robust estimation algorithm is applied for each window. The restoration algorithm is tested by comparing it to traditional methods on several different images.

  16. Near-infrared spectroscopic tissue imaging for medical applications

    DOEpatents

    Demos, Stavros; Staggs, Michael C.

    2006-12-12

    Near infrared imaging using elastic light scattering and tissue autofluorescence are explored for medical applications. The approach involves imaging using cross-polarized elastic light scattering and tissue autofluorescence in the Near Infra-Red (NIR) coupled with image processing and inter-image operations to differentiate human tissue components.

  17. Near-infrared spectroscopic tissue imaging for medical applications

    DOEpatents

    Demos; Stavros , Staggs; Michael C.

    2006-03-21

    Near infrared imaging using elastic light scattering and tissue autofluorescence are explored for medical applications. The approach involves imaging using cross-polarized elastic light scattering and tissue autofluorescence in the Near Infra-Red (NIR) coupled with image processing and inter-image operations to differentiate human tissue components.

  18. Application Of Zone Plates In Interferometric Positioning

    NASA Astrophysics Data System (ADS)

    Jaroszewicz, Zbigniew; Moreno, Vincente; Bara Vinas, Salvador

    1990-04-01

    The usefullness of the zone plates (ZP) to the optical alignment and displacements measurement is discussed basing on examples of parabolic (PZP) and equilateral hyperbolic ZP (EHZP). Any displacement of the ZP from the position occupied during its recording creates the interference patterns between diffracted beam and its undiffracted counterpart. The shape of this pattern is explicitly determined by the kind and range of the misalignment. The PZP enables the accurate measurement of the linear motion in the direction parallel to the foci line with the control of undesired deviations in perpendicular directions. EHZP offers a possibility of strict point positioning for all possible degrees of movement freedom (including in-plane rotations), in contrary to the commonly used spherical ZP. Simple experiments supporting the analysis are presented.

  19. Applications of high-resolution remote sensing image data

    NASA Technical Reports Server (NTRS)

    Strome, W. M.; Leckie, D.; Miller, J.; Buxton, R.

    1990-01-01

    There are many situations in which the image resolution of satellite data is insufficient to provide the detail required for resource management and environmental monitoring. This paper will focus on applications of high-resolution (0.4 to 10 m) airborne multispectral and imaging spectrometer data acquired in Canada using the MEIS II multispectral line imager and the PMI imaging spectrometer. Applications discussed will include forestry, mapping, and geobotany.

  20. Development of image mappers for hyperspectral biomedical imaging applications

    PubMed Central

    Kester, Robert T.; Gao, Liang; Tkaczyk, Tomasz S.

    2010-01-01

    A new design and fabrication method is presented for creating large-format (>100 mirror facets) image mappers for a snapshot hyperspectral biomedical imaging system called an image mapping spectrometer (IMS). To verify this approach a 250 facet image mapper with 25 multiple-tilt angles is designed for a compact IMS that groups the 25 subpupils in a 5 × 5 matrix residing within a single collecting objective's pupil. The image mapper is fabricated by precision diamond raster fly cutting using surface-shaped tools. The individual mirror facets have minimal edge eating, tilt errors of <1 mrad, and an average roughness of 5.4 nm. PMID:20357875

  1. Imaging terahertz radar for security applications

    NASA Astrophysics Data System (ADS)

    Semenov, Alexei; Richter, Heiko; Böttger, Ute; Hübers, Heinz-Wilhelm

    2008-04-01

    Detection of concealed threats is a key issue in public security. In short range applications, passive imagers operating at millimeter wavelengths fulfill this task. However, for larger distances, they will suffer from limited spatial resolution. We will describe the design and performance of 0.8-THz imaging radar that is capable to detect concealed objects at a distance of more than 20 meter. The radar highlights the target with the built-in cw transmitter and analyses the returned signal making use of a heterodyne receiver with a single superconducting hot-electron bolometric mixer. With an integration time of 0.3 sec, the receiver distinguishes a temperature difference of 2 K at the 20 m distance. Both the transmitter and the receiver use the same modified Gregorian telescope consisting from two offset elliptic mirrors. The primary mirror defines limits the lateral resolution of the radar to 2 cm at 20 m distance. At this distance, the field of view of the radar has the diameter 0.5 m. It is sampled with a high-speed conical scanner that allows for a frame time less than 5 sec. The transmitter delivers to the target power with a density less than ten microwatt per squared centimeter, which is harmless for human beings. The radar implements a sensor fusion technique that greatly improves the ability to identify concealed objects.

  2. Wavelet Technique Applications in Planetary Nebulae Images

    NASA Astrophysics Data System (ADS)

    Leal Ferreira, M. L.; Rabaça, C. R.; Cuisinier, F.; Epitácio Pereira, D. N.

    2009-05-01

    Through the application of the wavelet technique to a planetary nebulae image, we are able to identify different scale sizes structures present in its wavelet coefficient decompositions. In a multiscale vision model, an object is defined as a hierarchical set of these structures. We can then use this model to independently reconstruct the different objects that compose the nebulae. The result is the separation and identification of superposed objects, some of them with very low surface brightness, what makes them, in general, very difficult to be seen in the original images due to the presence of noise. This allows us to make a more detailed analysis of brightness distribution in these sources. In this project, we use this method to perform a detailed morphological study of some planetary nebulae and to investigate whether one of them indeed shows internal temperature fluctuations. We have also conducted a series of tests concerning the reliability of the method and the confidence level of the objects detected. The wavelet code used in this project is called OV_WAV and was developed by the UFRJ's Astronomy Departament team.

  3. Note: Near infrared interferometric silicon wafer metrology.

    PubMed

    Choi, M S; Park, H M; Joo, K N

    2016-04-01

    In this investigation, two near infrared (NIR) interferometric techniques for silicon wafer metrology are described and verified with experimental results. Based on the transparent characteristic of NIR light to a silicon wafer, the fiber based spectrally resolved interferometry can measure the optical thickness of the wafer and stitching low coherence scanning interferometry can reconstruct entire surfaces of the wafer. PMID:27131722

  4. Quantum Limits in Interferometric GW Antennas

    NASA Technical Reports Server (NTRS)

    Romano, R.; Barone, F.; Maddalena, P.; Solimeno, S.; Zaccaria, F.; Manko, M. A.; Manko, V. I.

    1996-01-01

    We discuss a model for interferometric GW antennas illuminated by a laser beam and a vacuum squeezed field. The sensitivity of the antenna will depend on the properties of the radiation entering the two ports and on the optical characteristics of the interferometer components, e.g. mirrors, beam-splitter, lenses.

  5. Stability in computed optical interferometric tomography (Part I): Stability requirements

    PubMed Central

    Shemonski, Nathan D.; Adie, Steven G.; Liu, Yuan-Zhi; South, Fredrick A.; Carney, P. Scott; Boppart, Stephen A.

    2014-01-01

    As imaging systems become more advanced and acquire data at faster rates, increasingly dynamic samples can be imaged without concern of motion artifacts. For optical interferometric techniques such as optical coherence tomography, it often follows that initially, only amplitude-based data are utilized due to unstable or unreliable phase measurements. As systems progress, stable phase maps can also be acquired, enabling more advanced, phase-dependent post-processing techniques. Here we report an investigation of the stability requirements for a class of phase-dependent post-processing techniques – numerical defocus and aberration correction with further extensions to techniques such as Doppler, phase-variance, and optical coherence elastography. Mathematical analyses and numerical simulations over a variety of instabilities are supported by experimental investigations. PMID:25321004

  6. Damage Assessment Map from Interferometric Coherence

    NASA Astrophysics Data System (ADS)

    Yun, S.; Fielding, E. J.; Simons, M.; Rosen, P. A.; Owen, S. E.; Webb, F.

    2010-12-01

    Large earthquakes cause buildings to collapse, which often claims the lives of many. For example, 2010 Haiti earthquake killed about 230,000 people, with about 280,000 buildings collapsed or severely damaged. When a major earthquake hits an urban area, one of the most critical information for rescue operations is rapid and accurate assessment of building-collapse areas. From a study on 2003 Bam earthquake in Iran, interferometric coherence was proved useful for earthquake damage assessment (Fielding et al., 2005) when similar perpendicular baselines can be found for pre- and coseismic interferometric pairs and when there is little temporal and volume decorrelation. In this study we develop a new algorithm to create a more robust and accurate damage assessment map using interferometric coherence despite different interferometric baselines and with other decorrelation sources. We test the algorithm on a building block that recently underwent demolition, which is a proxy for building collapse due to earthquakes, for new construction in the City of Pasadena, California. The size of the building block is about 150 m E-W and 300 m N-S, and the demolition project started on April 23, 2007 and continued until January 22, 2008. After we process Japanese L-band ALOS PALSAR data with ROI_PAC, an interferometric coherence map that spans the demolition period is registered to a coherence map before the demolition, and the relative bias of the coherence values are removed, then a causality constraint is applied to enhance the change due to demolition. The results show clear change in coherence at the demolition site. We improve the signal-to-noise ratio of the coherence change at the demolition site from 17.3 (for simple difference) to 44.6 (with the new algorithm). The damage assessment map algorithm will become more useful with the emergence of InSAR missions with more frequent data acquisition, such as Sentinel-1 and DESDynI.

  7. An Innovative Transponder-Based Interferometric Radar for Vibration Measurements

    SciTech Connect

    Coppi, F.; Cerutti, A.; Farina, P.; De Pasquale, G.; Novembrini, G.

    2010-05-28

    Ground-based radar interferometry has recently emerged as an innovative technology of remote sensing, able to accurately measure the static or dynamic displacement of several points of a structure. This technique in the last couple of years has been applied to different types of structures, such as bridges, towers and chimneys. This paper presents a prototype system developed by IDS, originally aimed at measuring the structural vibrations of helicopter rotor blades, based on an interferometric technique and constituted by combination of a radar sensor and a series of transponders installed on the target structure. The main advantages of this solution with respect to conventional interferometric radars, are related to the increased spatial resolution of the system, provided by the possibility to discriminate different transponders installed within the same resolution cell of the radar sensor, and to the reduction of the ambient noise (e.g. multi-path) on the radar measurement. The first feature allows the use of the microwave technology even on target areas with limited dimensions, such as industrial facilities, while the second aspect may extend the use of radar interferometric systems to complex scenarios, where multi-reflections are expected due to the presence of natural targets with high reflectivity to the radar signal. In the paper, the system and its major characteristics are first described; subsequently, application to the measurement of ambient vibration response of a lab set-up is summarized. Then the data acquired on a rotating mock-up are reported and analyzed to identify natural frequencies and mode shapes of the investigated structure.

  8. An Innovative Transponder-Based Interferometric Radar for Vibration Measurements

    NASA Astrophysics Data System (ADS)

    Coppi, F.; Cerutti, A.; Farina, P.; De Pasquale, G.; Novembrini, G.

    2010-05-01

    Ground-based radar interferometry has recently emerged as an innovative technology of remote sensing, able to accurately measure the static or dynamic displacement of several points of a structure. This technique in the last couple of years has been applied to different types of structures, such as bridges, towers and chimneys. This paper presents a prototype system developed by IDS, originally aimed at measuring the structural vibrations of helicopter rotor blades, based on an interferometric technique and constituted by combination of a radar sensor and a series of transponders installed on the target structure. The main advantages of this solution with respect to conventional interferometric radars, are related to the increased spatial resolution of the system, provided by the possibility to discriminate different transponders installed within the same resolution cell of the radar sensor, and to the reduction of the ambient noise (e.g. multi-path) on the radar measurement. The first feature allows the use of the microwave technology even on target areas with limited dimensions, such as industrial facilities, while the second aspect may extend the use of radar interferometric systems to complex scenarios, where multi-reflections are expected due to the presence of natural targets with high reflectivity to the radar signal. In the paper, the system and its major characteristics are first described; subsequently, application to the measurement of ambient vibration response of a lab set-up is summarized. Then the data acquired on a rotating mock-up are reported and analyzed to identify natural frequencies and mode shapes of the investigated structure.

  9. Advances in Clinical and Biomedical Applications of Photoacoustic Imaging

    PubMed Central

    Su, Jimmy L.; Wang, Bo; Wilson, Katheryne E.; Bayer, Carolyn L.; Chen, Yun-Sheng; Kim, Seungsoo; Homan, Kimberly A.; Emelianov, Stanislav Y.

    2010-01-01

    Importance of the field Photoacoustic imaging is an imaging modality that derives image contrast from the optical absorption coefficient of the tissue being imaged. The imaging technique is able to differentiate between healthy and diseased tissue with either deeper penetration or higher resolution than other functional imaging modalities currently available. From a clinical standpoint, photoacoustic imaging has demonstrated safety and effectiveness in diagnosing diseased tissue regions using either endogenous tissue contrast or exogenous contrast agents. Furthermore, the potential of photoacoustic imaging has been demonstrated in various therapeutic interventions ranging from drug delivery and release to image-guided therapy and monitoring. Areas covered in this review This article reviews the current state of photoacoustic imaging in biomedicine from a technological perspective, highlights various biomedical and clinical applications of photoacoustic imaging, and gives insights on future directions. What the reader will gain Readers will learn about the various applications of photoacoustic imaging, as well as the various contrast agents that can be used to assist photoacoustic imaging. This review will highlight both pre-clinical and clinical uses for photoacoustic imaging, as well as discuss some of the challenges that must be addressed to move photoacoustic imaging into the clinical realm. Take home message Photoacoustic imaging offers unique advantages over existing imaging modalities. The imaging field is broad with many exciting applications for detecting and diagnosing diseased tissue or processes. Photoacoustics is also used in therapeutic applications to identify and characterize the pathology and then to monitor the treatment. Although the technology is still in its infancy, much work has been done in the pre-clinical arena, and photoacoustic imaging is fast approaching the clinical setting. PMID:21344060

  10. System for interferometric distortion measurements that define an optical path

    DOEpatents

    Bokor, Jeffrey; Naulleau, Patrick

    2003-05-06

    An improved phase-shifting point diffraction interferometer can measure both distortion and wavefront aberration. In the preferred embodiment, the interferometer employs an object-plane pinhole array comprising a plurality of object pinholes located between the test optic and the source of electromagnetic radiation and an image-plane mask array that is positioned in the image plane of the test optic. The image-plane mask array comprises a plurality of test windows and corresponding reference pinholes, wherein the positions of the plurality of pinholes in the object-plane pinhole array register with those of the plurality of test windows in image-plane mask array. Electromagnetic radiation that is directed into a first pinhole of object-plane pinhole array thereby creating a first corresponding test beam image on the image-plane mask array. Where distortion is relatively small, it can be directly measured interferometrically by measuring the separation distance between and the orientation of the test beam and reference-beam pinhole and repeating this process for at least one other pinhole of the plurality of pinholes of the object-plane pinhole array. Where the distortion is relative large, it can be measured by using interferometry to direct the stage motion, of a stage supporting the image-plane mask array, and then use the final stage motion as a measure of the distortion.

  11. New impedance and electrochemical image techniques for biological applications

    NASA Astrophysics Data System (ADS)

    Tao, N. J.

    2010-03-01

    A method to image local surface impedance and electrochemical current optically is developed for biological applications. The principle of the impedance imaging is based on sensitive dependence of surface plasmon resonance (SPR) on local surface charge density. The technique can image local surface impedance and charge while providing simultaneously a conventional surface plasmon resonance (SPR) image. By applying a potential modulation to a sensor surface, it is possible to obtain an image of the DC component, and the amplitude and phase images of the AC component. The DC image provides local molecular binding, as found in the conventional SPR imaging technique. The AC images are directly related to the local impedance of the surface. This imaging capability may be used as a new detection platform for DNA and protein microarrays, a new method for analyzing local molecular binding and interfacial processes and a new tool for imaging cells and tissues.

  12. Detection of weak seismic waves in sea-ground interface by fiber-optic interferometric seismometer

    NASA Astrophysics Data System (ADS)

    Kamenev, O. T.; Petrov, Yu S.; Khiznyak, R. V.; Romashko, R. V.

    2016-08-01

    The possibility of detection of weak seismic waves in sea-ground interface by fiberoptic interferometric seismometer is experimentally demonstrated. High sensitivity of the seismometer to acceleration 10-7 m/s2 is provided by application of original multiturn fiber- optical sensing element. Long term stability of the seismometer operation is provided by feedback control of the interferometer working point.

  13. A microwave imaging spectrometer for security applications

    NASA Astrophysics Data System (ADS)

    Jirousek, Matthias; Peichl, Markus; Suess, Helmut

    2010-04-01

    In recent years the security of people and critical infrastructures is of increasing interest. Passive microwave sensors in the range of 1 - 100 GHz are suitable for the detection of concealed objects and wide-area surveillance through poor weather and at day and night time. The enhanced extraction of significant information about an observed object is enabled by the use of a spectral sensitive system. For such a spectral radiometer in the microwave range also some depth information can be extracted. The usable frequency range is thereby dependent on the application. For through-wall imaging or detection of covert objects such as for example landmines, the lower microwave range is best suited. On the other hand a high spatial resolution requires higher frequencies or instruments with larger physical dimensions. The drawback of a large system is the required movement of a mirror or a deflecting plate in the case of a mechanical scanner system, or a huge amount of receivers in a fully-electronic instrument like a focal plane array. An innovative technique to overcome these problems is the application of aperture synthesis using a highly thinned array. The combination of spectral radiometric measurements within a wide frequency band, at a high resolution, and requiring a minimum of receivers and only minor moving parts led to the development of the ANSAS instrument (Abbildendes Niederfrequenz-Spektrometer mit Apertursynthese). ANSAS is a very flexible aperture synthesis technology demonstrator for the analysis of main features and interactions concerning high spatial resolution and spectral sensing within a wide frequency range. It consists of a rotated linear thinned array and thus the spatial frequency spectrum is measured on concentric circles. Hence the number of receivers and correlators is reduced considerably compared to a fully two-dimensional array, and measurements still can be done in a reasonable time. In this paper the basic idea of ANSAS and its setup

  14. Interferometric Views of Star Formation

    NASA Astrophysics Data System (ADS)

    Plambeck, R. L.; Wright, M. C. H.

    1999-10-01

    Many studies of molecular clouds require quantitative comparisons of images at widely different wavelengths. For example, one may map dust spectral index variations to search for evidence of grain growth in protostellar cores, or use 3-2/2-1/1-0 C18O line ratios to derive gas kinetic temperatures, or search for chemical abundance anomalies caused by shocks or MHD waves. ALMA will dramatically improve the accuracy of these measurements because it will provide almost complete sampling of visibilities across the u,v plane, allowing one to synthesize mathematically perfect, matched beams at different wavelengths. The reliability of such comparisons will be limited by the difficulty in measuring the flux from extended structures. For a homogeneous array such as ALMA, visibilities on spacings smaller than the antenna diameter are recovered by mosaicing. Pointing and surface errors lead to errors in these data, limiting the image fidelity (Cornwell, Holdaway, & Uson 1993), particularly at submillimeter wavelengths. One could improve the image fidelity by measuring the short spacing visibilities directly with an auxiliary array of smaller antennas.

  15. Application of Uncooled Monolithic Thermoelectric Linear Arrays to Imaging Radiometers

    NASA Astrophysics Data System (ADS)

    Kruse, Paul W.

    Introduction Identification of Incipient Failure of Railcar Wheels Technical Description of the Model IR 1000 Imaging Radiometer Performance of the Model IR 1000 Imaging Radiometer Initial Application Summary Imaging Radiometer for Predictive and Preventive Maintenance Description Operation Specifications Summary References INDEX CONTENTS OF VOLUMES IN THIS SERIES

  16. Interferometric synthetic aperture radar: building tomorrow's tools today

    USGS Publications Warehouse

    Lu, Zhong

    2006-01-01

    A synthetic aperture radar (SAR) system transmits electromagnetic (EM) waves at a wavelength that can range from a few millimeters to tens of centimeters. The radar wave propagates through the atmosphere and interacts with the Earth’s surface. Part of the energy is reflected back to the SAR system and recorded. Using a sophisticated image processing technique, called SAR processing (Curlander and McDonough, 1991), both the intensity and phase of the reflected (or backscattered) signal of each ground resolution element (a few meters to tens of meters) can be calculated in the form of a complex-valued SAR image representing the reflectivity of the ground surface. The amplitude or intensity of the SAR image is determined primarily by terrain slope, surface roughness, and dielectric constants, whereas the phase of the SAR image is determined primarily by the distance between the satellite antenna and the ground targets, slowing of the signal by the atmosphere, and the interaction of EM waves with ground surface. Interferometric SAR (InSAR) imaging, a recently developed remote sensing technique, utilizes the interaction of EM waves, referred to as interference, to measure precise distances. Very simply, InSAR involves the use of two or more SAR images of the same area to extract landscape topography and its deformation patterns.

  17. New medium wave infrared stimulable phosphor for image intensifier applications

    NASA Astrophysics Data System (ADS)

    Soltani, Peter K.; Pierce, Gregory; Storti, George M.; Wrigley, Charles Y.

    1990-07-01

    A great deal of effort is presently being focused on developing high resolution, high sensitivity medium wavelength IR (MWIR) imaging systems for a variety of applications. These range from thermal imaging for industrial applications to military applications for detecting vehicles, missiles, etc. The present state-of-the-art method for MWIR imaging consists of fabricating linear and two-dimensional arrays of semiconductor detectors, such as HgCdTe, InSb, etc., and incorporating these into an appropriate optical imaging system. However, such devices are difficult to make and are very expensive. A new detector medium is described which can be fabricated at low cost for use in MWIR imaging. Specifically, the new medium is an electron trapping material capable of up-converting MWIR to visible wavelengths, which can be easily detected with a commercial camera system. This paper will describe the specific performance characteristics of the new phosphor material and its application in MWIR imaging.

  18. Robust image modeling technique with a bioluminescence image segmentation application

    NASA Astrophysics Data System (ADS)

    Zhong, Jianghong; Wang, Ruiping; Tian, Jie

    2009-02-01

    A robust pattern classifier algorithm for the variable symmetric plane model, where the driving noise is a mixture of a Gaussian and an outlier process, is developed. The veracity and high-speed performance of the pattern recognition algorithm is proved. Bioluminescence tomography (BLT) has recently gained wide acceptance in the field of in vivo small animal molecular imaging. So that it is very important for BLT to how to acquire the highprecision region of interest in a bioluminescence image (BLI) in order to decrease loss of the customers because of inaccuracy in quantitative analysis. An algorithm in the mode is developed to improve operation speed, which estimates parameters and original image intensity simultaneously from the noise corrupted image derived from the BLT optical hardware system. The focus pixel value is obtained from the symmetric plane according to a more realistic assumption for the noise sequence in the restored image. The size of neighborhood is adaptive and small. What's more, the classifier function is base on the statistic features. If the qualifications for the classifier are satisfied, the focus pixel intensity is setup as the largest value in the neighborhood.Otherwise, it will be zeros.Finally,pseudo-color is added up to the result of the bioluminescence segmented image. The whole process has been implemented in our 2D BLT optical system platform and the model is proved.

  19. Perceived Image Quality Improvements from the Application of Image Deconvolution to Retinal Images from an Adaptive Optics Fundus Imager

    NASA Astrophysics Data System (ADS)

    Soliz, P.; Nemeth, S. C.; Erry, G. R. G.; Otten, L. J.; Yang, S. Y.

    Aim: The objective of this project was to apply an image restoration methodology based on wavefront measurements obtained with a Shack-Hartmann sensor and evaluating the restored image quality based on medical criteria.Methods: Implementing an adaptive optics (AO) technique, a fundus imager was used to achieve low-order correction to images of the retina. The high-order correction was provided by deconvolution. A Shack-Hartmann wavefront sensor measures aberrations. The wavefront measurement is the basis for activating a deformable mirror. Image restoration to remove remaining aberrations is achieved by direct deconvolution using the point spread function (PSF) or a blind deconvolution. The PSF is estimated using measured wavefront aberrations. Direct application of classical deconvolution methods such as inverse filtering, Wiener filtering or iterative blind deconvolution (IBD) to the AO retinal images obtained from the adaptive optical imaging system is not satisfactory because of the very large image size, dificulty in modeling the system noise, and inaccuracy in PSF estimation. Our approach combines direct and blind deconvolution to exploit available system information, avoid non-convergence, and time-consuming iterative processes. Results: The deconvolution was applied to human subject data and resulting restored images compared by a trained ophthalmic researcher. Qualitative analysis showed significant improvements. Neovascularization can be visualized with the adaptive optics device that cannot be resolved with the standard fundus camera. The individual nerve fiber bundles are easily resolved as are melanin structures in the choroid. Conclusion: This project demonstrated that computer-enhanced, adaptive optic images have greater detail of anatomical and pathological structures.

  20. MEASURING THE DIRECTION AND ANGULAR VELOCITY OF A BLACK HOLE ACCRETION DISK VIA LAGGED INTERFEROMETRIC COVARIANCE

    SciTech Connect

    Johnson, Michael D.; Loeb, Abraham; Shiokawa, Hotaka; Chael, Andrew A.; Doeleman, Sheperd S.

    2015-11-10

    We show that interferometry can be applied to study irregular, rapidly rotating structures, as are expected in the turbulent accretion flow near a black hole. Specifically, we analyze the lagged covariance between interferometric baselines of similar lengths but slightly different orientations. For a flow viewed close to face-on, we demonstrate that the peak in the lagged covariance indicates the direction and angular velocity of the emission pattern from the flow. Even for moderately inclined flows, the covariance robustly estimates the flow direction, although the estimated angular velocity can be significantly biased. Importantly, measuring the direction of the flow as clockwise or counterclockwise on the sky breaks a degeneracy in accretion disk inclinations when analyzing time-averaged images alone. We explore the potential efficacy of our technique using three-dimensional, general relativistic magnetohydrodynamic simulations, and we highlight several baseline pairs for the Event Horizon Telescope (EHT) that are well-suited to this application. These results indicate that the EHT may be capable of estimating the direction and angular velocity of the emitting material near Sgr A*, and they suggest that a rotating flow may even be utilized to improve imaging capabilities.

  1. Interferometric estimation of ice sheet motion and topography

    NASA Technical Reports Server (NTRS)

    Joughlin, Ian; Kwok, Ron; Fahnestock, Mark; Winebrenner, Dale; Tulaczyk, Slawek; Gogenini, Prasad

    1997-01-01

    With ERS-1/2 satellite radar interferometry, it is possible to make measurements of glacier motion with high accuracy and fine spatial resolution. Interferometric techniques were applied to map velocity and topography for several outlet glaciers in Greenland. For the Humboldt and Petermann glaciers, data from several adjacent tracks were combined to make a wide-area map that includes the enhanced flow regions of both glaciers. The discharge flux of the Petermann glacier upstream of the grounding line was estimated, thereby establishing the potential use of ERS-1/2 interferometric data for monitoring ice-sheet discharge. Interferograms collected along a single track are sensitive to only one component of motion. By utilizing data from ascending and descending passes and by making a surface-parallel flow assumption, it is possible to measure the full three-dimensional vector flow field. The application of this technique for an area on the Ryder glacier is demonstrated. Finally, ERS-1/2 interferograms were used to observe a mini-surge on the Ryder glacier that occurred in autumn of 1995.

  2. Focused-laser interferometric position sensor

    SciTech Connect

    Friedman, Stephen J.; Barwick, Brett; Batelaan, Herman

    2005-12-15

    We describe a simple method to measure the position shifts of an object with a range of tens of micrometers using a focused-laser (FL) interferometric position sensor. In this article we examine the effects of mechanical vibration on FL and Michelson interferometers. We tested both interferometers using vibration amplitudes ranging from 0 to 20 {mu}m. Our FL interferometer has a resolution much better than the diffraction grating periodicities of 10 and 14 {mu}m used in our experiments. A FL interferometer provides improved mechanical stability at the expense of spatial resolution. Our experimental results show that Michelson interferometers cannot be used when the vibration amplitude is more than an optical wavelength. The main purpose of this article is to demonstrate that a focused-laser interferometric position sensor can be used to measure the position shifts of an object on a less sensitive, micrometer scale when the vibration amplitude is too large to use a Michelson interferometer.

  3. An image denoising application using shearlets

    NASA Astrophysics Data System (ADS)

    Sevindir, Hulya Kodal; Yazici, Cuneyt

    2013-10-01

    Medical imaging is a multidisciplinary field related to computer science, electrical/electronic engineering, physics, mathematics and medicine. There has been dramatic increase in variety, availability and resolution of medical imaging devices for the last half century. For proper medical imaging highly trained technicians and clinicians are needed to pull out clinically pertinent information from medical data correctly. Artificial systems must be designed to analyze medical data sets either in a partially or even a fully automatic manner to fulfil the need. For this purpose there has been numerous ongoing research for finding optimal representations in image processing and computer vision [1, 18]. Medical images almost always contain artefacts and it is crucial to remove these artefacts to obtain healthy results. Out of many methods for denoising images, in this paper, two denoising methods, wavelets and shearlets, have been applied to mammography images. Comparing these two methods, shearlets give better results for denoising such data.

  4. Novel multispectral imaging microscope with applications to biomedicine

    NASA Astrophysics Data System (ADS)

    Zeng, Libo; Wu, Qiongshui; Ke, Hengyu; Zheng, Hong; Hu, Yaojun; Ding, Yi

    2005-03-01

    This paper describes a novel multispectral imaging microscope that can simultaneously record both spectral and spatial information of a sample, which can take advantage of spatial image processing and spectroscopic analysis techniques. A Liquid Crystal Tunable Filter device is used for fast wavelength selection and a cooled two-dimensional monochrome CCD for image detection. In order to acquire images that are not so dependent on imaging devices, a clever CCD exposure time control and a software based spectral and spatial calibration process is performed to diminish the influence of illumination, optic ununiformity, CCD"s spectral response curve and optic throughput property. A set of multispectral image processing and analysis software package is developed, which covers not only general image processing and analysis functions, and also provides powerful analysis tools for multispectral image data, including multispectral image acquisition, illumination and system response calibration, spectral analysis and etc. The combination of spatial and spectral analysis makes it an ideal tool for the applications to biomedicine. In this paper, two applications in biomedicine are also presented. One is medical image segmentation. Using multispectral imaging techniques, a mass of experiments on both marrow bone and cervical cell images showed that our segmentation results are highly satisfactory while with low computational cost. Another is biological imaging spectroscopic analysis in the study of pollen grains in rice. The results showed that the transmittance analysis of multispectral pollen images can accurately identify the pollen abortion stage of male-sterile rice, and can easily distinguish a variety of male sterile cytoplasm.

  5. Interferometric observations of an artificial satellite.

    NASA Technical Reports Server (NTRS)

    Preston, R. A.; Ergas, R.; Hinteregger, H. F.; Knight, C. A.; Robertson, D. S.; Shapiro, I. I.; Whitney, A. R.; Rogers, A. E. E.; Clark, T. A.

    1972-01-01

    Very-long-baseline interferometric observations of radio signals from the TACSAT synchronous satellite, even though extending over only 7 hours, have enabled an excellent orbit to be deduced. Precision in differential delay and delay-rate measurements reached 0.15 nanosecond and 0.05 picosecond per second, respectively. The results from this initial three-station experiment demonstrate the feasibility of using the method for accurate satellite tracking and for geodesy.

  6. Analysis of the interferometric Ronchi test.

    PubMed

    Malacara, D

    1990-09-01

    It is well known that the Ronchi test has two equivalent interpretations, Physical, as an interferometer, or geometrical, as if the fringes were just shadows from the fringes on the ruling. The second interpretation is nearly always used in practice because it is simpler. However, the disadvantage is that the irradiance profile of the fringes cannot be calculated with this theory. Here, the interferometric interpretation of the test will be used to obtain the irradiance profile and the sharpness of the fringes.

  7. Applications of energy filtered imaging in biology.

    PubMed

    Shuman, H; Somlyo, A V; Safer, D; Frey, T; Somlyo, A P

    1983-01-01

    We describe the use of a magnetic sector spectrometer positioned below the projection chamber of an electron microscope for energy filtered transmission imaging. The spectrometer used has circular pole face edges and is corrected for second order aberrations. A round EM lens is placed after the sector to form a real image of the virtual achromatic image produced by the spectrometer. A slit placed in the dispersion plane allows the passage of electrons in a selected energy range. The filtered image is projected onto a transmission phosphor and acquired with a silicon intensified TV camera and stored in digital form on computer disk. Filtered images are taken at two energies, one immediately preceding (pre-edge) and one on the characteristic energy loss (edge). To obtain images showing the distribution of elements, background subtraction is performed by either subtraction or division of edge and pre-edge images. The optical properties of the imaging system are described and the results are illustrated by energy filtered images of single ferritin molecules (Fe M2,3 and C k), the phosphorus distribution in ribosomes (PL2,3) and the localization of calcium in muscle (Ca L2, 3). The major advantage of the system, compared to other energy filtered imaging methods, is that it can be readily adapted to existing high vacuum microscopes without the necessity of modifying the column to insert a spectrometer. PMID:6635570

  8. A null-steering viewpoint of interferometric SAR

    SciTech Connect

    BICKEL,DOUGLAS L.

    2000-05-02

    Interferometric synthetic aperture radar (IFSAR) extends the two-dimensional imaging capability of traditional synthetic aperture radar to three-dimensions by using an aperture in the elevation plane to estimate the 3-D structure of the target. The operation of this additional aperture can be viewed from a null-steering point of view, rather than the traditional phase determination point of view. Knowing that IFSAR can be viewed from the null-steering perspective allows one to take advantage of the mathematical foundation developed for null-steering arrays. In addition, in some problems of interest in IFSAR the null-steering perspective provides better intuition and suggests alternative solutions. One example is the problem of estimating building height where layover is present.

  9. Interferometric Radio Transient Reconstruction in Compressed Sensing Framework

    NASA Astrophysics Data System (ADS)

    Jiang, M.; Girard, J. N.; Starck, J.-L.; Corbel, S.; Tasse, C.

    2015-12-01

    Imaging by aperture synthesis from interferometric data is a well-known, but strong ill-posed inverse problem. Strong and faint radio sources can be imaged unambiguously using time and frequency integration to gather more Fourier samples of the sky. , However, these imagers assumes a steady sky and the complexity of the problem increases when transients radio sources are also present in the data. Hopefully, in the context of transient imaging, the spatial and temporal information are separable which enable extension of an imager fit for a steady sky. We introduce independent spatial and temporal wavelet dictionaries to sparsely represent the transient in both spatial domain and temporal domain. These dictionaries intervenes in a new reconstruction method developed in the Compressed Sensing (CS) framework and using a primal-dual splitting algorithm. According to the preliminary tests in different noise regimes, this new ``Time-agile'' (or 2D-1D) method seems to be efficient in detecting and reconstructing the transients temporal dependence.

  10. Infrared active polarimetric imaging system controlled by image segmentation algorithms: application to decamouflage

    NASA Astrophysics Data System (ADS)

    Vannier, Nicolas; Goudail, François; Plassart, Corentin; Boffety, Matthieu; Feneyrou, Patrick; Leviandier, Luc; Galland, Frédéric; Bertaux, Nicolas

    2016-05-01

    We describe an active polarimetric imager with laser illumination at 1.5 µm that can generate any illumination and analysis polarization state on the Poincar sphere. Thanks to its full polarization agility and to image analysis of the scene with an ultrafast active-contour based segmentation algorithm, it can perform adaptive polarimetric contrast optimization. We demonstrate the capacity of this imager to detect manufactured objects in different types of environments for such applications as decamouflage and hazardous object detection. We compare two imaging modes having different number of polarimetric degrees of freedom and underline the characteristics that a polarimetric imager aimed at this type of applications should possess.

  11. Sparse multipass 3D SAR imaging: applications to the GOTCHA data set

    NASA Astrophysics Data System (ADS)

    Austin, Christian D.; Ertin, Emre; Moses, Randolph L.

    2009-05-01

    Typically in SAR imaging, there is insufficient data to form well-resolved three-dimensional (3D) images using traditional Fourier image reconstruction; furthermore, scattering centers do not persist over wide-angles. In this work, we examine 3D non-coherent wide-angle imaging on the GOTCHA Air Force Research Laboratory (AFRL) data set; this data set consists of multipass complete circular aperture radar data from a scene at AFRL, with each pass varying in elevation as a result of aircraft flight dynamics . We compare two algorithms capable of forming well-resolved 3D images over this data set: regularized lp least-squares inversion, and non-uniform multipass interferometric SAR (IFSAR).

  12. Spectroscopy and terahertz imaging for sigillography applications

    NASA Astrophysics Data System (ADS)

    Mounaix, P.; Younus, A.; Delagnes, J. C.; Abraham, E.; Canioni, L.; Fabre, M.

    2011-02-01

    Sigillography is the science that studies the manifold aspects of the seals. A seal can be defined as an imprint obtained on a malleable medium by imprinting an incised matrix, which transfers on it the characteristic signs of a person or an institution. We use THz spectroscopy and imaging for non-destructive evaluation of natural seals. Using a time domain THz spectroscopy and imaging system, THz transmission images are generated in the 0.1-3 THz range.

  13. Versatile architecture for image recognition applications

    NASA Astrophysics Data System (ADS)

    Sacramone, Anthony; Scola, Joseph; Shazeer, Dov J.

    1992-03-01

    Architectures for the development of image recognition algorithms must support the implementation of systematic procedures for solving image recognition problems. All too often, designers develop image recognition architectures in an ad hoc fashion which lacks the structure to meet long term needs. Vendors typically supply customers with standard image processing libraries and display tools. Combining these tools and formulating development strategies have remained stumbling blocks in the design of complete image recognition algorithm development environments. In this paper, an architecture is presented which provides a well defined framework, and at the same time is sufficiently flexible to accommodate images of multiple sensor and data types. The primary components of the architecture are: ground-truthing, preprocessing (which includes image processing and segmentation), feature extraction, classification, and performance analysis. Powerful and well defined data structures are exploited for each of the primary components. Groups of programs called tasks manipulate one or more of these data structures, each task belonging to one of the primary components. Multiple tasks can be executed in an unsupervised mode over an entire database of images. Results are then subjected to performance analysis and feedback. A description of the primary components and how they are integrated to facilitate the rapid prototyping and development of image recognition algorithms is presented.

  14. BOOK REVIEW: Infrared Thermal Imaging: Fundamentals, Research and Applications Infrared Thermal Imaging: Fundamentals, Research and Applications

    NASA Astrophysics Data System (ADS)

    Planinsic, Gorazd

    2011-09-01

    Ten years ago, a book with a title like this would be interesting only to a narrow circle of specialists. Thanks to rapid advances in technology, the price of thermal imaging devices has dropped sharply, so they have, almost overnight, become accessible to a wide range of users. As the authors point out in the preface, the growth of this area has led to a paradoxical situation: now there are probably more infrared (IR) cameras sold worldwide than there are people who understand the basic physics behind them and know how to correctly interpret the colourful images that are obtained with these devices. My experience confirms this. When I started using the IR camera during lectures on the didactics of physics, I soon realized that I needed more knowledge, which I later found in this book. A wide range of potential readers and topical areas provides a good motive for writing a book such as this one, but it also represents a major challenge for authors, as compromises in the style of writing and choice of topics are required. The authors of this book have successfully achieved this, and indeed done an excellent job. This book addresses a wide range of readers, from engineers, technicians, and physics and science teachers in schools and universities, to researchers and specialists who are professionally active in the field. As technology in this area has made great progress in recent times, this book is also a valuable guide for those who opt to purchase an infrared camera. Chapters in this book could be divided into three areas: the fundamentals of IR thermal imaging and related physics (two chapters); IR imaging systems and methods (two chapters) and applications, including six chapters on pedagogical applications; IR imaging of buildings and infrastructure, industrial applications, microsystems, selected topics in research and industry, and selected applications from other fields. All chapters contain numerous colour pictures and diagrams, and a rich list of relevant

  15. Emerging applications of conjugated polymers in molecular imaging.

    PubMed

    Li, Junwei; Liu, Jie; Wei, Chen-Wei; Liu, Bin; O'Donnell, Matthew; Gao, Xiaohu

    2013-10-28

    In recent years, conjugated polymers have attracted considerable attention from the imaging community as a new class of contrast agent due to their intriguing structural, chemical, and optical properties. Their size and emission wavelength tunability, brightness, photostability, and low toxicity have been demonstrated in a wide range of in vitro sensing and cellular imaging applications, and have just begun to show impact in in vivo settings. In this Perspective, we summarize recent advances in engineering conjugated polymers as imaging contrast agents, their emerging applications in molecular imaging (referred to as in vivo uses in this paper), as well as our perspectives on future research.

  16. Magnetic resonance imaging: present and future applications

    PubMed Central

    Johnston, Donald L.; Liu, Peter; Wismer, Gary L.; Rosen, Bruce R.; Stark, David D.; New, Paul F.J.; Okada, Robert D.; Brady, Thomas J.

    1985-01-01

    Magnetic resonance (MR) imaging has created considerable excitement in the medical community, largely because of its great potential to diagnose and characterize many different disease processes. However, it is becoming increasingly evident that, because MR imaging is similar to computed tomography (CT) scanning in identifying structural disorders and because it is more costly and difficult to use, this highly useful technique must be judged against CT before it can become an accepted investigative tool. At present MR imaging has demonstrated diagnostic superiority over CT in a limited number of important, mostly neurologic, disorders and is complementary to CT in the diagnosis of certain other disorders. For most of the remaining organ systems its usefulness is not clear, but the lack of ionizing radiation and MR's ability to produce images in any tomographic plane may eventually prove to be advantageous. The potential of MR imaging to display in-vivo spectra, multinuclear images and blood-flow data makes it an exciting investigative technique. At present, however, MR imaging units should be installed only in medical centres equipped with the clinical and basic research facilities that are essential to evaluate the ultimate role of this technique in the care of patients. ImagesFig. 5Fig. 6Fig. 7Fig. 8Fig. 9Fig. 10Fig. 11Fig. 12Fig. 13Fig. 14 PMID:3884120

  17. Application of coherent 10 micron imaging lidar

    SciTech Connect

    Simpson, M.L.; Hutchinson, D.P.; Richards, R.K.; Bennett, C.A.

    1997-04-01

    With the continuing progress in mid-IR array detector technology and high bandwidth fan-outs, i.f. electronics, high speed digitizers, and processing capability, true coherent imaging lidar is becoming a reality. In this paper experimental results are described using a 10 micron coherent imaging lidar.

  18. Imaging-Genetics Applications in Child Psychiatry

    ERIC Educational Resources Information Center

    Pine, Daniel S.; Ernst, Monique; Leibenluft, Ellen

    2010-01-01

    Objective: To place imaging-genetics research in the context of child psychiatry. Method: A conceptual overview is provided, followed by discussion of specific research examples. Results: Imaging-genetics research is described linking brain function to two specific genes, for the serotonin-reuptake-transporter protein and a monoamine oxidase…

  19. Photoacoustic tomography: applications for atherosclerosis imaging

    NASA Astrophysics Data System (ADS)

    Sangha, Gurneet S.; Goergen, Craig J.

    2016-08-01

    Atherosclerosis is a debilitating condition that increases a patient’s risk for intermittent claudication, limb amputation, myocardial infarction, and stroke, thereby causing approximately 50% of deaths in the western world. Current diagnostic imaging techniques, such as ultrasound, digital subtraction angiography, computed tomography angiography, magnetic resonance angiography, and optical imaging remain suboptimal for detecting development of early stage plaques. This is largely due to the lack of compositional information, penetration depth, and/or clinical efficiency of these traditional imaging techniques. Photoacoustic imaging has emerged as a promising modality that could address some of these limitations to improve the diagnosis and characterization of atherosclerosis-related diseases. Photoacoustic imaging uses near-infrared light to induce acoustic waves, which can be used to recreate compositional images of tissue. Recent developments in photoacoustic techniques show its potential in noninvasively characterizing atherosclerotic plaques deeper than traditional optical imaging approaches. In this review, we discuss the significance and development of atherosclerosis, current and novel clinical diagnostic methods, and recent works that highlight the potential of photoacoustic imaging for both experimental and clinical studies of atherosclerosis.

  20. Improving terrain height estimates from RADARSAT interferometric measurements

    SciTech Connect

    Thompson, P.A.; Eichel, P.H.; Calloway, T.M.

    1998-03-01

    The authors describe two methods of combining two-pass RADAR-SAT interferometric phase maps with existing DTED (digital terrain elevation data) to produce improved terrain height estimates. The first is a least-squares estimation procedure that fits the unwrapped phase data to a phase map computed from the DTED. The second is a filtering technique that combines the interferometric height map with the DTED map based on spatial frequency content. Both methods preserve the high fidelity of the interferometric data.

  1. Mathematical Morphology Techniques For Image Processing Applications In Biomedical Imaging

    NASA Astrophysics Data System (ADS)

    Bartoo, Grace T.; Kim, Yongmin; Haralick, Robert M.; Nochlin, David; Sumi, Shuzo M.

    1988-06-01

    Mathematical morphology operations allow object identification based on shape and are useful for grouping a cluster of small objects into one object. Because of these capabilities, we have implemented and evaluated this technique for our study of Alzheimer's disease. The microscopic hallmark of Alzheimer's disease is the presence of brain lesions known as neurofibrillary tangles and senile plaques. These lesions have distinct shapes compared to normal brain tissue. Neurofibrillary tangles appear as flame-shaped structures, whereas senile plaques appear as circular clusters of small objects. In order to quantitatively analyze the distribution of these lesions, we have developed and applied the tools of mathematical morphology on the Pixar Image Computer. As a preliminary test of the accuracy of the automatic detection algorithm, a study comparing computer and human detection of senile plaques was performed by evaluating 50 images from 5 different patients. The results of this comparison demonstrates that the computer counts correlate very well with the human counts (correlation coefficient = .81). Now that the basic algorithm has been shown to work, optimization of the software will be performed to improve its speed. Also future improvements such as local adaptive thresholding will be made to the image analysis routine to further improve the systems accuracy.

  2. Measurement of non-common path static aberrations in an interferometric camera by phase diversity

    NASA Astrophysics Data System (ADS)

    Yan, Zhaojun; Herbst, Thomas M.; Yang, Pengqian; Bizenberger, Peter; Zhang, Xianyu; Conrad, Albert R.; Bertram, Thomas; Kuerster, Martin; Rix, Hans-Walter; Li, Xinyang; Rao, Changhui

    2012-10-01

    LINC-NIRVANA (LN) is a near-infrared image-plane beam combiner with advanced, multi-conjugated adaptive optics for the Large Binocular Telescope. Non-common path aberrations (NCPAs) between the near-infrared science camera and the wave-front sensor (WFS) are unseen by the WFS and therefore are not corrected in closed loop. This would prevent LN from achieving its ultimate performance. We use a modified phase diversity technique to measure the internal optical static aberrations and hence the NCPAs. Phase diversity is a methodology for estimating wave-front aberrations by solving an unconstrained optimization problem from multiple images whose pupil phases differ from one another by a known amount. We conduct computer simulations of the reconstruction of aberrations of an optical system with the phase diversity method. In the reconstruction, we fit the wave-front to Zernike polynomials to reduce the number of variables. The limited-memory Broyden-Fletcher-Goldfarb-Shanno (L-BFGS) algorithm is very well suited to phase diversity (PD) due to its good performance in solving large scale optimization problems. The main constraint for the implementation of PD for LN is that we cannot add extra components to the internal interferometric camera imaging system to obtain infocus and defocus images. In this paper, we introduce a new method, namely shifting the focal plane source, not the detector, to overcome this constraint. Some experiments were done to test and verify this method and the results are presented and discussed. The study shows that the method is very flexible and the paper gives practical guidelines for the application of phase diversity methods to characterize adaptive optics systems.

  3. Stability in computed optical interferometric tomography (Part II): in vivo stability assessment

    PubMed Central

    Shemonski, Nathan D.; Ahmad, Adeel; Adie, Steven G.; Liu, Yuan-Zhi; South, Fredrick A.; Carney, P. Scott; Boppart, Stephen A.

    2014-01-01

    Stability is of utmost importance to a wide range of phase-sensitive processing techniques. In Doppler optical coherence tomography and optical coherence elastography, in addition to defocus and aberration correction techniques such as interferometric synthetic aperture microscopy and computational/digital adaptive optics, a precise understanding of the system and sample stability helps to guide the system design and choice of imaging parameters. This article focuses on methods to accurately and quantitatively measure the stability of an imaging configuration in vivo. These methods are capable of partially decoupling axial from transverse motion and are compared against the stability requirements for computed optical interferometric tomography laid out in the first part of this article. PMID:25321016

  4. Shack-Hartmann wavefront sensing using interferometric focusing of light onto guide-stars.

    PubMed

    Tao, Xiaodong; Dean, Ziah; Chien, Christopher; Azucena, Oscar; Bodington, Dare; Kubby, Joel

    2013-12-16

    Optical microscopy provides noninvasive imaging of biological tissues at subcellular level. The optical aberrations induced by the inhomogeneous refractive index of biological samples limits the resolution and can decrease the penetration depth. To compensate refractive aberrations, adaptive optics with Shack-Hartmann wavefront sensing has been used in microscopes. Wavefront measurement requires light from a guide-star inside of the sample. The scattering effect limits the intensity of the guide-star, hence reducing the signal to noise ratio of the wavefront measurement. In this paper, we demonstrate the use of interferometric focusing of excitation light onto a guide-star embedded deeply in tissue to increase its fluorescent intensity, thus overcoming the excitation signal loss caused by scattering. With interferometric focusing, we more than doubled the signal to noise ratio of the laser guide-star through scattering tissue as well as potentially extend the imaging depth through using AO microscopy.

  5. Multimodality Image Fusion-Guided Procedures: Technique, Accuracy, and Applications

    SciTech Connect

    Abi-Jaoudeh, Nadine; Kruecker, Jochen; Kadoury, Samuel; Kobeiter, Hicham; Venkatesan, Aradhana M. Levy, Elliot Wood, Bradford J.

    2012-10-15

    Personalized therapies play an increasingly critical role in cancer care: Image guidance with multimodality image fusion facilitates the targeting of specific tissue for tissue characterization and plays a role in drug discovery and optimization of tailored therapies. Positron-emission tomography (PET), magnetic resonance imaging (MRI), and contrast-enhanced computed tomography (CT) may offer additional information not otherwise available to the operator during minimally invasive image-guided procedures, such as biopsy and ablation. With use of multimodality image fusion for image-guided interventions, navigation with advanced modalities does not require the physical presence of the PET, MRI, or CT imaging system. Several commercially available methods of image-fusion and device navigation are reviewed along with an explanation of common tracking hardware and software. An overview of current clinical applications for multimodality navigation is provided.

  6. Laser applications and system considerations in ocular imaging

    PubMed Central

    Elsner, Ann E.; Muller, Matthew S.

    2009-01-01

    We review laser applications for primarily in vivo ocular imaging techniques, describing their constraints based on biological tissue properties, safety, and the performance of the imaging system. We discuss the need for cost effective sources with practical wavelength tuning capabilities for spectral studies. Techniques to probe the pathological changes of layers beneath the highly scattering retina and diagnose the onset of various eye diseases are described. The recent development of several optical coherence tomography based systems for functional ocular imaging is reviewed, as well as linear and nonlinear ocular imaging techniques performed with ultrafast lasers, emphasizing recent source developments and methods to enhance imaging contrast. PMID:21052482

  7. In vivo Coherent Raman Imaging for Neuroscience Applications

    NASA Astrophysics Data System (ADS)

    Cote, Daniel

    2010-08-01

    The use of coherent Raman imaging is described for applications in neuroscience. Myelin imaging of the spinal cord can be performed with Raman imaging through the use of the vibration in carbon-hydrogen bonds, dominant in lipids. First, we demonstrate in vivo histomorphometry in live animal for characterization of myelin-related nervous system pathologies. This is used to characterize spinal cord health during multiple sclerosis. Second, Raman spectroscopy of tissue is discussed. We discuss the challenges that live animal imaging brings, together with important aspects of coherent Raman imaging in tissue.

  8. Application of optical coherence tomography based microangiography for cerebral imaging

    NASA Astrophysics Data System (ADS)

    Baran, Utku; Wang, Ruikang K.

    2016-03-01

    Requirements of in vivo rodent brain imaging are hard to satisfy using traditional technologies such as magnetic resonance imaging and two-photon microscopy. Optical coherence tomography (OCT) is an emerging tool that can easily reach at high speeds and provide high resolution volumetric images with a relatively large field of view for rodent brain imaging. Here, we provide the overview of recent developments of functional OCT based imaging techniques for neuroscience applications on rodents. Moreover, a summary of OCT-based microangiography (OMAG) studies for stroke and traumatic brain injury cases on rodents are provided.

  9. Application of ASAP in integral imaging

    NASA Astrophysics Data System (ADS)

    Wang, Hong-xia; Xu, Zhi-li; Wen, Shao-jie; Wu, Chun-hong

    2012-10-01

    Integral imaging (II) is a technique that is capable of displaying 3D images with continuous parallax in full natural color. At present Integral Imaging is a popular three-dimensional imaging technology. It is becoming the most perspective technique in developing next generation three-dimensional TV (3DTV) and visualization field due to its outstanding advantages. The micro-lens array is used in recording and replaying 3D scene information in this technique with true color, simply reconstruction and non-relevant light source. In order to research really many precision instrument are required. But the price is too high to set up a complicated authentic imaging system. In the same time the imaging condition is very difficult to satisfy. ASAP (Advanced System Analysis Program) is an advanced imitates optical software to solve reality optical questions. It is used in many research territories. In this paper the ASAP software is proposed to simulate and model the micro-lens array sheet. The ray tracing and energy distribution is completed. According to the study results we can optimum lens designing through modifying the focal length, aperture size and imaging position. We hope the study cost can be reduced and the efficiency can be improved through the use of simulation method to optical design software ASAP.

  10. Deconvolution of interferometric data using interior point iterative algorithms

    NASA Astrophysics Data System (ADS)

    Theys, C.; Lantéri, H.; Aime, C.

    2016-09-01

    We address the problem of deconvolution of astronomical images that could be obtained with future large interferometers in space. The presentation is made in two complementary parts. The first part gives an introduction to the image deconvolution with linear and nonlinear algorithms. The emphasis is made on nonlinear iterative algorithms that verify the constraints of non-negativity and constant flux. The Richardson-Lucy algorithm appears there as a special case for photon counting conditions. More generally, the algorithm published recently by Lanteri et al. (2015) is based on scale invariant divergences without assumption on the statistic model of the data. The two proposed algorithms are interior-point algorithms, the latter being more efficient in terms of speed of calculation. These algorithms are applied to the deconvolution of simulated images corresponding to an interferometric system of 16 diluted telescopes in space. Two non-redundant configurations, one disposed around a circle and the other on an hexagonal lattice, are compared for their effectiveness on a simple astronomical object. The comparison is made in the direct and Fourier spaces. Raw "dirty" images have many artifacts due to replicas of the original object. Linear methods cannot remove these replicas while iterative methods clearly show their efficacy in these examples.

  11. Image Processing Application for Cognition (IPAC) - Traditional and Emerging Topics in Image Processing in Astronomy (Invited)

    NASA Astrophysics Data System (ADS)

    Pesenson, M.; Roby, W.; Helou, G.; McCollum, B.; Ly, L.; Wu, X.; Laine, S.; Hartley, B.

    2008-08-01

    A new application framework for advanced image processing for astronomy is presented. It implements standard two-dimensional operators, and recent developments in the field of non-astronomical image processing (IP), as well as original algorithms based on nonlinear partial differential equations (PDE). These algorithms are especially well suited for multi-scale astronomical images since they increase signal to noise ratio without smearing localized and diffuse objects. The visualization component is based on the extensive tools that we developed for Spitzer Space Telescope's observation planning tool Spot and archive retrieval tool Leopard. It contains many common features, combines images in new and unique ways and interfaces with many astronomy data archives. Both interactive and batch mode processing are incorporated. In the interactive mode, the user can set up simple processing pipelines, and monitor and visualize the resulting images from each step of the processing stream. The system is platform-independent and has an open architecture that allows extensibility by addition of plug-ins. This presentation addresses astronomical applications of traditional topics of IP (image enhancement, image segmentation) as well as emerging new topics like automated image quality assessment (QA) and feature extraction, which have potential for shaping future developments in the field. Our application framework embodies a novel synergistic approach based on integration of image processing, image visualization and image QA (iQA).

  12. High-energy proton imaging for biomedical applications

    DOE PAGES

    Prall, Matthias; Durante, Marco; Berger, Thomas; Przybyla, B.; Graeff, C.; Lang, Phillipp M.; LaTessa, Ciara; Shestov, Less; Simoniello, P.; Danly, Christopher R.; et al

    2016-06-10

    The charged particle community is looking for techniques exploiting proton interactions instead of X-ray absorption for creating images of human tissue. Due to multiple Coulomb scattering inside the measured object it has shown to be highly non-trivial to achieve sufficient spatial resolution. We present imaging of biological tissue with a proton microscope. This device relies on magnetic optics, distinguishing it from most published proton imaging methods. For these methods reducing the data acquisition time to a clinically acceptable level has turned out to be challenging. In a proton microscope, data acquisition and processing are much simpler. This device even allowsmore » imaging in real time. The primary medical application will be image guidance in proton radiosurgery. Proton images demonstrating the potential for this application are presented. As a result, tomographic reconstructions are included to raise awareness of the possibility of high-resolution proton tomography using magneto-optics.« less

  13. High-energy proton imaging for biomedical applications.

    PubMed

    Prall, M; Durante, M; Berger, T; Przybyla, B; Graeff, C; Lang, P M; LaTessa, C; Shestov, L; Simoniello, P; Danly, C; Mariam, F; Merrill, F; Nedrow, P; Wilde, C; Varentsov, D

    2016-01-01

    The charged particle community is looking for techniques exploiting proton interactions instead of X-ray absorption for creating images of human tissue. Due to multiple Coulomb scattering inside the measured object it has shown to be highly non-trivial to achieve sufficient spatial resolution. We present imaging of biological tissue with a proton microscope. This device relies on magnetic optics, distinguishing it from most published proton imaging methods. For these methods reducing the data acquisition time to a clinically acceptable level has turned out to be challenging. In a proton microscope, data acquisition and processing are much simpler. This device even allows imaging in real time. The primary medical application will be image guidance in proton radiosurgery. Proton images demonstrating the potential for this application are presented. Tomographic reconstructions are included to raise awareness of the possibility of high-resolution proton tomography using magneto-optics. PMID:27282667

  14. High-energy proton imaging for biomedical applications

    NASA Astrophysics Data System (ADS)

    Prall, M.; Durante, M.; Berger, T.; Przybyla, B.; Graeff, C.; Lang, P. M.; Latessa, C.; Shestov, L.; Simoniello, P.; Danly, C.; Mariam, F.; Merrill, F.; Nedrow, P.; Wilde, C.; Varentsov, D.

    2016-06-01

    The charged particle community is looking for techniques exploiting proton interactions instead of X-ray absorption for creating images of human tissue. Due to multiple Coulomb scattering inside the measured object it has shown to be highly non-trivial to achieve sufficient spatial resolution. We present imaging of biological tissue with a proton microscope. This device relies on magnetic optics, distinguishing it from most published proton imaging methods. For these methods reducing the data acquisition time to a clinically acceptable level has turned out to be challenging. In a proton microscope, data acquisition and processing are much simpler. This device even allows imaging in real time. The primary medical application will be image guidance in proton radiosurgery. Proton images demonstrating the potential for this application are presented. Tomographic reconstructions are included to raise awareness of the possibility of high-resolution proton tomography using magneto-optics.

  15. Radionuclide Imaging Applications in Cardiomyopathies and Heart Failure.

    PubMed

    Harinstein, Matthew E; Soman, Prem

    2016-03-01

    Multiple epidemiological factors including population aging and improved survival after acute coronary syndromes have contributed to a heart failure (HF) prevalence in the USA in epidemic proportions. In the absence of transplantation, HF remains a progressive disease with poor prognosis. The structural and functional abnormalities of the myocardium in HF can be assessed by various radionuclide imaging techniques. Radionuclide imaging may be uniquely suited to address several important clinical questions in HF such as identifying etiology and guiding the selection of patients for coronary revascularization. Newer approaches such as autonomic innervation imaging, phase analysis for synchrony assessment, and other molecular imaging techniques continue to expand the applications of radionuclide imaging in HF. In this manuscript, we review established and evolving applications of radionuclide imaging for the diagnosis, risk stratification, and management of HF. PMID:26841785

  16. High-energy proton imaging for biomedical applications

    PubMed Central

    Prall, M.; Durante, M.; Berger, T.; Przybyla, B.; Graeff, C.; Lang, P. M.; LaTessa, C.; Shestov, L.; Simoniello, P.; Danly, C.; Mariam, F.; Merrill, F.; Nedrow, P.; Wilde, C.; Varentsov, D.

    2016-01-01

    The charged particle community is looking for techniques exploiting proton interactions instead of X-ray absorption for creating images of human tissue. Due to multiple Coulomb scattering inside the measured object it has shown to be highly non-trivial to achieve sufficient spatial resolution. We present imaging of biological tissue with a proton microscope. This device relies on magnetic optics, distinguishing it from most published proton imaging methods. For these methods reducing the data acquisition time to a clinically acceptable level has turned out to be challenging. In a proton microscope, data acquisition and processing are much simpler. This device even allows imaging in real time. The primary medical application will be image guidance in proton radiosurgery. Proton images demonstrating the potential for this application are presented. Tomographic reconstructions are included to raise awareness of the possibility of high-resolution proton tomography using magneto-optics. PMID:27282667

  17. Mineral mapping and applications of imaging spectroscopy

    USGS Publications Warehouse

    Clark, R.N.; Boardman, J.; Mustard, J.; Kruse, F.; Ong, C.; Pieters, C.; Swayze, G.A.

    2006-01-01

    Spectroscopy is a tool that has been used for decades to identify, understand, and quantify solid, liquid, or gaseous materials, especially in the laboratory. In disciplines ranging from astronomy to chemistry, spectroscopic measurements are used to detect absorption and emission features due to specific chemical bonds, and detailed analyses are used to determine the abundance and physical state of the detected absorbing/emitting species. Spectroscopic measurements have a long history in the study of the Earth and planets. Up to the 1990s remote spectroscopic measurements of Earth and planets were dominated by multispectral imaging experiments that collect high-quality images in a few, usually broad, spectral bands or with point spectrometers that obtained good spectral resolution but at only a few spatial positions. However, a new generation of sensors is now available that combines imaging with spectroscopy to create the new discipline of imaging spectroscopy. Imaging spectrometers acquire data with enough spectral range, resolution, and sampling at every pixel in a raster image so that individual absorption features can be identified and spatially mapped (Goetz et al., 1985).

  18. Application of infrared imaging in ferrocyanide tanks

    SciTech Connect

    Morris, K.L.; Mailhot, R.B. Jr.; McLaren, J.M.; Morris, K.L.

    1994-09-28

    This report analyzes the feasibility of using infrared imaging techniques and scanning equipment to detect potential hot spots within ferrocyanide waste tanks at the Hanford Site. A hot spot is defined as a volumetric region within a waste tank with an excessively warm temperature that is generated by radioactive isotopes. The thermal image of a hot spot was modeled by computer. this model determined the image an IR system must detect. Laboratory and field tests of the imaging system are described, and conclusions based on laboratory and field data are presented. The report shows that infrared imaging is capable of detecting hot spots in ferrocyanide waste tanks with depths of up to 3.94 m (155 in.). The infrared imaging system is a useful technology for initial evaluation and assessment of hot spots in the majority of ferrocyanide waste tanks at the Hanford Site. The system will not allow an exact hot spot and temperature determination, but it will provide the necessary information to determine the worst-case hot spot detected in temperature patterns. Ferrocyanide tanks are one type of storage tank on the Watch List. These tanks are identified as priority 1 Hanford Site Tank farm Safety Issues.

  19. Using stereoscopic imaging for visualization applications

    SciTech Connect

    Adelson, S.J.

    1994-02-01

    The purpose of scientific visualization is to simplify the analysis of numerical data by rendering the information as an image. Even when the image is familiar, as in the case of terrain data, preconceptions about what the image should look like and deceptive image artifacts can create misconceptions about what information is actually contained in the scene. One way of aiding the development of unambiguous visualizations is to add stereoscopic depth to the image. Despite the recent proliferation of affordable stereoscopic viewing equipment, few researchers are at this time taking advantage of stereo in their visualizations. It is generally perceived that the rendering time will have to be doubled in order to generate the pair, and so stereoscopic viewing is sacrificed in the name of expedient rendering. We show that this perception is often invalid. The second half of a stereoscopic image can be generated from the first half for a fraction of the computational cost of complete rendering, usually no more than 50% of the cost and in many cases as little as 5%. Using the techniques presented here, the benefits of stereoscopy can be added to existing visualization systems for only a small cost over current single-frame rendering methods.

  20. Laser interferometric system for six-axis motion measurement

    SciTech Connect

    Zhang Zhipeng; Menq, C.-H.

    2007-08-15

    This article presents the development of a precision laser interferometric system, which is designed to achieve six-axis motion measurement for real-time applications. By combining the advantage of the interferometer with a retroreflector and that of the interferometer with a plane mirror reflector, the system is capable of simultaneously measuring large transverse motions along and large rotational motions about three orthogonal axes. Based on optical path analysis along with the designed kinematics of the system, a closed form relationship between the six-axis motion parameters of the object being measured and the readings of the six laser interferometers is established. It can be employed as a real-time motion sensor for various six-axis motion control stages. A prototype is implemented and integrated with a six-axis magnetic levitation stage to illustrate its resolution and measurement range.

  1. Development and Evaluation of Science and Technology Education Program Using Interferometric SAR

    NASA Astrophysics Data System (ADS)

    Ito, Y.; Ikemitsu, H.; Nango, K.

    2016-06-01

    This paper proposes a science and technology education program to teach junior high school students to measure terrain changes by using interferometric synthetic aperture radar (SAR). The objectives of the proposed program are to evaluate and use information technology by performing SAR data processing in order to measure ground deformation, and to incorporate an understanding of Earth sciences by analyzing interferometric SAR processing results. To draft the teaching guidance plan for the developed education program, this study considers both science and technology education. The education program was used in a Japanese junior high school. An educational SAR processor developed by the authors and the customized Delft object-oriented radar interferometric software package were employed. Earthquakes as diastrophism events were chosen as practical teaching materials. The selected events indicate clear ground deformation in differential interferograms with high coherence levels. The learners were able to investigate the ground deformations and disasters caused by the events. They interactively used computers and became skilled at recognizing the knowledge and techniques of information technology, and then they evaluated the technology. Based on the results of pre- and post-questionnaire surveys and self-evaluation by the learners, it was clarified that the proposed program was applicable for junior high school education, and the learners recognized the usefulness of Earth observation technology by using interferometric SAR. The usefulness of the teaching materials in the learning activities was also shown through the practical teaching experience.

  2. Fluorescence and Cerenkov luminescence imaging. Applications in small animal research.

    PubMed

    Schwenck, J; Fuchs, K; Eilenberger, S H L; Rolle, A-M; Castaneda Vega, S; Thaiss, W M; Maier, F C

    2016-01-01

    This review addresses small animal optical imaging (OI) applications in diverse fields of basic research. In the past, OI has proven to be cost- and time-effective, allows real-time imaging as well as high-throughput analysis and does not imply the usage of ionizing radiation (with the exception of Cerenkov imaging applications). Therefore, this technique is widely spread - not only geographically, but also among very different fields of basic research - and is represented by a large body of publications. Originally used in oncology research, OI is nowadays emerging in further areas like inflammation and infectious disease as well as neurology. Besides fluorescent probe-based contrast, the feasibility of Cerenkov luminescence imaging (CLI) has been recently shown in small animals and thus represents a new route for future applications. Thus, this review will focus on examples for OI applications in inflammation, infectious disease, cell tracking as well as neurology, and provides an overview over CLI. PMID:27067794

  3. Compressive sampling for time critical microwave imaging applications

    PubMed Central

    O'Halloran, Martin; McGinley, Brian; Conceicao, Raquel C.; Kilmartin, Liam; Jones, Edward; Glavin, Martin

    2014-01-01

    Across all biomedical imaging applications, there is a growing emphasis placed on reducing data acquisition and imaging times. This research explores the use of a technique, known as compressive sampling or compressed sensing (CS), as an efficient technique to minimise the data acquisition time for time critical microwave imaging (MWI) applications. Where a signal exhibits sparsity in the time domain, the proposed CS implementation allows for sub-sampling acquisition in the frequency domain and consequently shorter imaging times, albeit at the expense of a slight degradation in reconstruction quality of the signals as the compression increases. This Letter focuses on ultra wideband (UWB) radar MWI applications where reducing acquisition is of critical importance therefore a slight degradation in reconstruction quality may be acceptable. The analysis demonstrates the effectiveness and suitability of CS with UWB applications. PMID:26609368

  4. Optimizing signal and image processing applications using Intel libraries

    NASA Astrophysics Data System (ADS)

    Landré, Jérôme; Truchetet, Frédéric

    2007-01-01

    This paper presents optimized signal and image processing libraries from Intel Corporation. Intel Performance Primitives (IPP) is a low-level signal and image processing library developed by Intel Corporation to optimize code on Intel processors. Open Computer Vision library (OpenCV) is a high-level library dedicated to computer vision tasks. This article describes the use of both libraries to build flexible and efficient signal and image processing applications.

  5. Real-time hyperspectral imaging for food safety applications

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Multispectral imaging systems with selected bands can commonly be used for real-time applications of food processing. Recent research has demonstrated several image processing methods including binning, noise removal filter, and appropriate morphological analysis in real-time mode can remove most fa...

  6. Interferometric Radar Observations of Glaciar San Rafael, Chile

    NASA Technical Reports Server (NTRS)

    Rignot, Eric; Forster, Richard; Isacks, Bryan

    1996-01-01

    Interferometric radar observations of Glaciar San Rafael, Chile, were collected in October 1994 by NASA's Spaceborne Imaging Radar C (SIR-C) at both L- (24cm) and C-band frequency (5.6cm), with vertical transmit and receive polarization. The C-band data did not yield good geophysical products, because the temporal coherence of the signal was significantly reduced after 24h. The L-band data were, however, successfully employed to map the surface topography of the icefield with a 10m uncertainty in height, and measure ice velocity with a precision of 4 mm/d or 1.4 m/a. The corresponding error in strain rates is 0.05/a at a 30 m horizontal spacing. The one-dimensional interferometric velocities were subsequently converted to horizontal displacements by assuming a flow direction and complemented by feature-tracking results near the calving front. The results provide a comprehensive view of the ice-flow dynamics of Glaciar San Rafael. The glacier has a core of rapid flow, 4.5 km in width and 3.5 degrees in average slope,surrounded by slower moving ice, not by rock. Ice velocity is 2.6 m/d or 0.95 km/a near the equilibrium line altitude (1200m), increasing rapidly before the glacier enters the narrower terminal valley, to reach 17.5 m/d or 6.4 km/a at the calving front. Strain rates are dominated by lateral shearing at the glacier margins (0.4-0.7/a), except for the terminal-valley section, where longitudinal strain rates average close to 1/a. This spectacular longitudinal increase in ice velocity in the last few kilometers may be a fundamental feature of tidewater glaciers.

  7. Interferometric observations of an artificial satellite.

    PubMed

    Preston, R A; Ergas, R; Hinteregger, H F; Knight, C A; Robertson, D S; Shapiro, I I; Whitney, A R; Rogers, A E; Clark, T A

    1972-10-27

    Very-long-baseline interferometric observations of radio signals from the TACSAT synchronous satellite, even though extending over only 7 hours, have enabled an excellent orbit to be deduced. Precision in differenced delay and delay-rate measurements reached 0.15 nanosecond ( approximately 5 centimeters in equivalent differenced distance) and 0.05 picosecond per second ( approximately 0.002 centimeter per second in equivalent differenced velocity), respectively. The results from this initial three-station experiment demonstrate the feasibility of using the method for accurate satellite tracking and for geodesy. Comparisons are made with other techniques.

  8. Light-pulse atom interferometric device

    DOEpatents

    Biedermann, Grant; McGuinness, Hayden James Evans; Rakholia, Akash; Jau, Yuan-Yu; Schwindt, Peter; Wheeler, David R.

    2016-03-22

    An atomic interferometric device useful, e.g., for measuring acceleration or rotation is provided. The device comprises at least one vapor cell containing a Raman-active chemical species, an optical system, and at least one detector. The optical system is conformed to implement a Raman pulse interferometer in which Raman transitions are stimulated in a warm vapor of the Raman-active chemical species. The detector is conformed to detect changes in the populations of different internal states of atoms that have been irradiated by the optical system.

  9. Imaging Systems For Application In Harsh Environments

    NASA Astrophysics Data System (ADS)

    Grothues, H.-G.; Michaelis, H.; Behnke, T.; Bresch, W.; Koldewey, E.; Lichopoj, A.; Tschentscher, M.; Alicke, P.

    Imaging systems operating in the wavelength domain between the near UV and the mid IR (about 300 nm to > 5 (m) play a crucial role in remote sensing from orbiters and in-situ lander measurements of planetary exploration space missions. Wide-angle and high-resolution cameras, IR imagers, and imaging spectrographs provide carto- graphic information on the morphology and topography of planetary surfaces, serve to characterize landing sites with their geological features like soils and rocks, de- liver data on the spectrophotometric characteristics of minerals, and contribute to at- mospheric reasearch. Moreover, imaging systems have the important task to present scientific missions to the general public. As resources during planetary missions are usually very limited imaging payloads have to be designed to have low mass and size, low power consumption, and to effectively handle the imaging data taking into ac- count the limited computing powers, mass memories and telemetry data rates (image data compression). Furthermore, the design has to cope with extremely harsh environ- ments such as, for example, high and very low temperatures, large temperature varia- tions and gradients, high mechanical loads (shocks), e.g. during landing on a planetary surface, a hostile particle radiation environment, and dusty or chemically aggressive atmospheres. The presentation discusses the requirements to be set up for planetary mission imaging systems, and gives an overview of the most important design mea- sures to be taken in order to be compliant with these requirements (e.g. miniatur- ization of electronics, light-weight materials, athermal and radiation tolerant design). The discussion comprises all subunits of imaging systems starting with the optics / the spectrograph and the detector unit, continuing with the data processing unit, and ending with peripheral equipment like e.g. drives, deployable booms, and illumina- tion devices for lander cameras. Examples are given of already

  10. Magnetic resonance imaging. Application to family practice.

    PubMed Central

    Goh, R. H.; Somers, S.; Jurriaans, E.; Yu, J.

    1999-01-01

    OBJECTIVE: To review indications, contraindications, and risks of using magnetic resonance imaging (MRI) in order to help primary care physicians refer patients appropriately for MRI, screen for contraindications to using MRI, and educate patients about MRI. QUALITY OF EVIDENCE: Recommendations are based on classic textbooks, the policies of our MRI group, and a literature search using MEDLINE with the MeSH headings magnetic resonance imaging, brain, musculoskeletal, and spine. The search was limited to human, English-language, and review articles. Evidence in favour of using MRI for imaging the head, spine, and joints is well established. For cardiac, abdominal, and pelvic conditions, MRI has been shown useful for certain indications, usually to complement other modalities. MAIN MESSAGE: For demonstrating soft tissue conditions, MRI is better than computed tomography (CT), but CT shows bone and acute bleeding better. Therefore, patients with trauma or suspected intracranial bleeding should have CT. Tumours, congenital abnormalities, vascular structures, and the cervical or thoracic spine show better on MRI. Either modality can be used for lower back pain. Cardiac, abdominal, and pelvic abnormalities should be imaged with ultrasound or CT before MRI. Contraindications for MRI are mainly metallic implants or shrapnel, severe claustrophobia, or obesity. CONCLUSIONS: With the increasing availability of MRI scanners in Canada, better understanding of the indications, contraindications, and risks will be helpful for family physicians and their patients. Images Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Figure 6 Figure 7 Figure 8 Figure 9 Figure 10 PMID:10509224

  11. Neural networks: Application to medical imaging

    NASA Technical Reports Server (NTRS)

    Clarke, Laurence P.

    1994-01-01

    The research mission is the development of computer assisted diagnostic (CAD) methods for improved diagnosis of medical images including digital x-ray sensors and tomographic imaging modalities. The CAD algorithms include advanced methods for adaptive nonlinear filters for image noise suppression, hybrid wavelet methods for feature segmentation and enhancement, and high convergence neural networks for feature detection and VLSI implementation of neural networks for real time analysis. Other missions include (1) implementation of CAD methods on hospital based picture archiving computer systems (PACS) and information networks for central and remote diagnosis and (2) collaboration with defense and medical industry, NASA, and federal laboratories in the area of dual use technology conversion from defense or aerospace to medicine.

  12. Electromagnetic inverse applications for functional brain imaging

    SciTech Connect

    Wood, C.C.

    1997-10-01

    This is the final report of a one-year, Laboratory Directed Research and Development (LDRD) project at Los Alamos National Laboratory (LANL). This project addresses an important mathematical and computational problem in functional brain imaging, namely the electromagnetic {open_quotes}inverse problem.{close_quotes} Electromagnetic brain imaging techniques, magnetoencephalography (MEG) and electroencephalography (EEG), are based on measurements of electrical potentials and magnetic fields at hundreds of locations outside the human head. The inverse problem is the estimation of the locations, magnitudes, and time-sources of electrical currents in the brain from surface measurements. This project extends recent progress on the inverse problem by combining the use of anatomical constraints derived from magnetic resonance imaging (MRI) with Bayesian and other novel algorithmic approaches. The results suggest that we can achieve significant improvements in the accuracy and robustness of inverse solutions by these two approaches.

  13. CCD imaging instruments for planetary spacecraft applications

    NASA Technical Reports Server (NTRS)

    Reilly, T. H.; Herring, M.

    1975-01-01

    The development of new spacecraft camera systems to be used in conjunction with CCD sensors is reported. A brief overview of the science objectives and engineering constraints which influence the design of cameras for deep space is followed by a review of two current development programs, one leading to a line scan imager and the other to an area array frame camera. For each of these, a general description of the imager is given. It is evident that currently available CCDs fall short of requirements in some respects.

  14. Real Time Fast Ultrasound Imaging Technology and Possible Applications

    NASA Astrophysics Data System (ADS)

    Cruza, J. F.; Perez, M.; Moreno, J. M.; Fritsch, C.

    In this work, a novel hardware architecture for fast ultrasound imaging based on FPGA devices is proposed. A key difference over other approaches is the unlimited scalability in terms of active channels without performance losses. Acquisition and processing tasks share the same hardware, eliminating communication bottlenecks with smaller size and power losses. These features make this system suitable to implement the most demanding imaging applications, like 3D Phased Array, Total Focusing Method, Vector Doppler, Image Compounding, High Speed Part Scanning and advanced elastographic techniques. A single medium sized FPGA allows beamforming up to 200 scan lines simultaneously, which is enough to perform most of the above mentioned applications in strict real time.

  15. Uncooled thermal imaging sensors for unattended sensor applications

    NASA Astrophysics Data System (ADS)

    Kohin, Margaret; Figler, Burton D.; Blackwell, Richard J.; Butler, Neal R.; Backer, Brian S.; Gurnee, Mark N.; Murphy, Bob H.

    2002-08-01

    320×240 and 640×480 small pixel uncooled microbolometer focal plane arrays have been developed that reduce overall sensor size, weight, power consumption, and cost. At the same time, these sensors still provide the high quality image resolution needed for target recognition and identification. These newly developed small uncooled thermal imaging sensors are being demonstrated in several attended and unattended sensor applications that include Unattended Ground Sensors, Micro Air Vehicles, and Infrared Helmet Sights. This paper describes recent developments at BAE SYSTEMS in uncooled microbolometer sensor technology for unattended sensor applications and presents the latest performance and image data for our 2nd generation systems.

  16. Infrared scanning images: An archeological application

    USGS Publications Warehouse

    Schaber, G.G.; Gumerman, G.J.

    1969-01-01

    Aerial infrared scanner images of an area near the Little Colorado River in north-central Arizona disclosed the existence of scattered clusters of parallel linear features in the ashfall area of Sunset Crater. The features are not obvious in conventional aerial photographs, and only one cluster could be recognized on the ground. Soil and pollen analyses reveal that they are prehistoric agricultural plots.

  17. Image analysis: Applications in materials engineering

    SciTech Connect

    Wojnar, L.

    1999-07-01

    This new practical book describes the basic principles of image acquisition, enhancement, measurement, and interpretation in very simple nonmathematical terms. it also provides solution-oriented algorithms and examples and case histories from industry and research, along with quick reference information on various specific problems. Included are numerous tables, graphs, charts, and working examples in detection of grain boundaries, pores, and chain structures.

  18. Comparison of mouse mammary gland imaging techniques and applications: Reflectance confocal microscopy, GFP Imaging, and ultrasound

    PubMed Central

    Tilli, Maddalena T; Parrish, Angela R; Cotarla, Ion; Jones, Laundette P; Johnson, Michael D; Furth, Priscilla A

    2008-01-01

    Background Genetically engineered mouse models of mammary gland cancer enable the in vivo study of molecular mechanisms and signaling during development and cancer pathophysiology. However, traditional whole mount and histological imaging modalities are only applicable to non-viable tissue. Methods We evaluated three techniques that can be quickly applied to living tissue for imaging normal and cancerous mammary gland: reflectance confocal microscopy, green fluorescent protein imaging, and ultrasound imaging. Results In the current study, reflectance confocal imaging offered the highest resolution and was used to optically section mammary ductal structures in the whole mammary gland. Glands remained viable in mammary gland whole organ culture when 1% acetic acid was used as a contrast agent. Our application of using green fluorescent protein expressing transgenic mice in our study allowed for whole mammary gland ductal structures imaging and enabled straightforward serial imaging of mammary gland ducts in whole organ culture to visualize the growth and differentiation process. Ultrasound imaging showed the lowest resolution. However, ultrasound was able to detect mammary preneoplastic lesions 0.2 mm in size and was used to follow cancer growth with serial imaging in living mice. Conclusion In conclusion, each technique enabled serial imaging of living mammary tissue and visualization of growth and development, quickly and with minimal tissue preparation. The use of the higher resolution reflectance confocal and green fluorescent protein imaging techniques and lower resolution ultrasound were complementary. PMID:18215290

  19. NMR imaging of components and materials for DOE application

    SciTech Connect

    Richardson, B.R.

    1993-12-01

    The suitability for using NMR imaging to characterize liquid, polymeric, and solid materials was reviewed. The most attractive applications for NMR imaging appear to be liquid-filled porous samples, partially cured polymers, adhesives, and potting compounds, and composite polymers/high explosives containing components with widely varying thermal properties. Solid-state NMR line-narrowing and signal-enhancing markedly improve the imaging possibilities of true solid and materials. These techniques provide unique elemental and chemical shift information for highly complex materials and complement images with similar spatial resolution, such as X-ray computed tomography (CT).

  20. Applications of magnetic resonance image segmentation in neurology

    NASA Astrophysics Data System (ADS)

    Heinonen, Tomi; Lahtinen, Antti J.; Dastidar, Prasun; Ryymin, Pertti; Laarne, Paeivi; Malmivuo, Jaakko; Laasonen, Erkki; Frey, Harry; Eskola, Hannu

    1999-05-01

    After the introduction of digital imagin devices in medicine computerized tissue recognition and classification have become important in research and clinical applications. Segmented data can be applied among numerous research fields including volumetric analysis of particular tissues and structures, construction of anatomical modes, 3D visualization, and multimodal visualization, hence making segmentation essential in modern image analysis. In this research project several PC based software were developed in order to segment medical images, to visualize raw and segmented images in 3D, and to produce EEG brain maps in which MR images and EEG signals were integrated. The software package was tested and validated in numerous clinical research projects in hospital environment.

  1. New imaging applications in the evaluation of pediatric renal disease.

    PubMed

    Norton, Karen I

    2003-04-01

    Continued improvements in imaging technology have changed many of the traditional diagnostic algorithms for evaluating pediatric renal disease. Newer imaging modalities offer more accurate, specific, and early diagnoses, but can be time consuming and costly. Less invasive modalities, such as ultrasound, computed tomography, and magnetic resonance imaging have widespread applications in pediatric practice. The risks of radiation exposure, contrast toxicity, and sedation or anesthesia versus the potential benefits of obtaining precise diagnostic information should always be considerations before electing any imaging procedure in children.

  2. Invited review article: Interferometric gravity wave detectors.

    PubMed

    Cella, G; Giazotto, A

    2011-10-01

    A direct detection of gravitational waves is still lacking today. A network of several earthbound interferometric detectors is currently operating with a continuously improving sensitivity. The window of interest for observation has a lower cut off in the frequency domain below some tens of hertz, determined by the effect of seismic motion. For larger frequencies, the sensitivity is limited by thermal effects below few hundreds of hertz and by the quantum nature of light above that value. Each of these sources of noise pose a big technological challenge to experimentalists, and there are big expectations for the next generation of detectors. A reduction of thermal effects by at least one order of magnitude will be obtained with new and carefully designed materials. At that point the quantum nature of light will become an issue, and the use of quantum non-demolition techniques will become mandatory. In this review, we discuss interferometric detection of gravitational waves from an instrumental point of view. We try to address conceptually important issues with an audience of non-experts in mind. A particular emphasis is given to the description of the current limitations and to the perspectives of beating them. PMID:22047273

  3. Invited review article: Interferometric gravity wave detectors.

    PubMed

    Cella, G; Giazotto, A

    2011-10-01

    A direct detection of gravitational waves is still lacking today. A network of several earthbound interferometric detectors is currently operating with a continuously improving sensitivity. The window of interest for observation has a lower cut off in the frequency domain below some tens of hertz, determined by the effect of seismic motion. For larger frequencies, the sensitivity is limited by thermal effects below few hundreds of hertz and by the quantum nature of light above that value. Each of these sources of noise pose a big technological challenge to experimentalists, and there are big expectations for the next generation of detectors. A reduction of thermal effects by at least one order of magnitude will be obtained with new and carefully designed materials. At that point the quantum nature of light will become an issue, and the use of quantum non-demolition techniques will become mandatory. In this review, we discuss interferometric detection of gravitational waves from an instrumental point of view. We try to address conceptually important issues with an audience of non-experts in mind. A particular emphasis is given to the description of the current limitations and to the perspectives of beating them.

  4. Computation of morphological texture features for medical imaging applications

    NASA Astrophysics Data System (ADS)

    Patel, Manish J.; Kehtarnavaz, Nasser; Dougherty, Edward R.; Batman, Sinan; Sivakumar, Krishnamoorthy; Popov, Antony T.

    1998-06-01

    Texture is an important attribute which is widely used in various image analysis applications. Among texture features, morphological texture features are least utilized in medical image analysis. From a computational standpoint, extracting morphological texture features from an image is a challenging task. The computational problem is made even greater in medical imaging applications where large images such as mammograms are to be analyzed. This paper discusses an efficient method to compute morphological texture features for any geometry of a structuring element corresponding to a texture type. A benchmarking of the code on three machines (Sun SPARC 20, Pentium II based Dell 400 workstation, and SGI Power Challenge 10000XL) as well as a parallel processing implementation was performed to obtain an optimum processing configuration. A sample processed mammogram is shown to illustrate the code outcome.

  5. Continuous-terahertz-wave molecular imaging system for biomedical applications

    NASA Astrophysics Data System (ADS)

    Zhang, Rui; Zhang, Liangliang; Wu, Tong; Wang, Ruixue; Zuo, Shasha; Wu, Dong; Zhang, Cunlin; Zhang, Jue; Fang, Jing

    2016-07-01

    Molecular imaging techniques are becoming increasingly important in biomedical research and potentially in clinical practice. We present a continuous-terahertz (THz)-wave molecular imaging system for biomedical applications, in which an infrared (IR) laser is integrated into a 0.2-THz reflection-mode continuous-THz-wave imaging system to induce surface plasmon polaritons on the nanoparticles and further improve the intensity of the reflected signal from the water around the nanoparticles. A strong and rapid increment of the reflected THz signal in the nanoparticle solution upon the IR laser irradiation is demonstrated, using either gold or silver nanoparticles. This low-cost, simple, and stable continuous-THz-wave molecular imaging system is suitable for miniaturization and practical imaging applications; in particular, it shows great promise for cancer diagnosis and nanoparticle drug-delivery monitoring.

  6. Recent applications of thermal imagers for security assessment

    SciTech Connect

    Bisbee, T.L.

    1997-06-01

    This paper discusses recent applications by Sandia National Laboratories of cooled and uncooled thermal infrared imagers to wide-area security assessment systems. Thermal imagers can solve many security assessment problems associated with the protection of high-value assets at military bases, secure installations, and commercial facilities. Thermal imagers can provide surveillance video from security areas or perimeters both day and night without expensive security lighting. Until fairly recently, thermal imagers required open-loop cryogenic cooling to operate. The high cost of these systems and associated maintenance requirements restricted their widespread use. However, recent developments in reliable, closed-loop, linear drive cryogenic coolers and uncooled infrared imagers have dramatically reduced maintenance requirements, extended MTBF, and are leading to reduced system cost. These technology developments are resulting in greater availability and practicality for military as well as civilian security applications.

  7. Image 100 procedures manual development: Applications system library definition and Image 100 software definition

    NASA Technical Reports Server (NTRS)

    Guseman, L. F., Jr.; Decell, H. P., Jr.

    1975-01-01

    An outline for an Image 100 procedures manual for Earth Resources Program image analysis was developed which sets forth guidelines that provide a basis for the preparation and updating of an Image 100 Procedures Manual. The scope of the outline was limited to definition of general features of a procedures manual together with special features of an interactive system. Computer programs were identified which should be implemented as part of an applications oriented library for the system.

  8. A High Performance Image Data Compression Technique for Space Applications

    NASA Technical Reports Server (NTRS)

    Yeh, Pen-Shu; Venbrux, Jack

    2003-01-01

    A highly performing image data compression technique is currently being developed for space science applications under the requirement of high-speed and pushbroom scanning. The technique is also applicable to frame based imaging data. The algorithm combines a two-dimensional transform with a bitplane encoding; this results in an embedded bit string with exact desirable compression rate specified by the user. The compression scheme performs well on a suite of test images acquired from spacecraft instruments. It can also be applied to three-dimensional data cube resulting from hyper-spectral imaging instrument. Flight qualifiable hardware implementations are in development. The implementation is being designed to compress data in excess of 20 Msampledsec and support quantization from 2 to 16 bits. This paper presents the algorithm, its applications and status of development.

  9. Advanced interferometric profile measurements through refractive media

    SciTech Connect

    Koev, Stephan T.; Ghodssi, Reza

    2008-09-15

    Optical profilers are valuable tools for the characterization of microelectromechanical systems (MEMSs). They use phase sifting interferometry (PSI) or vertical scanning interferometry to measure the topography of microscale structures with nanometer resolution. However, for many emerging MEMS applications, the sample needs to be imaged while placed in a liquid or in a package with a glass window. The increased refractive index of the transparent medium degrades the interference image contrast and prevents any measurement of the sample. We report on the modification of a Veeco NT1100 optical profiler to enable PSI measurements through refractive media. This approach can be applied to any other optical profiler with PSI capability. The modification consists in replacing the original illumination source with a custom-built narrow linewidth source, which increases the coherence length of the light and the contrast of the interference image. We present measurements taken with the modified configuration on samples covered with 3 mm water or 500 {mu}m glass, and we compare them to measurements of uncovered samples. We show that the measurement precision is only slightly reduced by the water and glass, and that it is still sufficiently high for typical MEMS applications. The described method can be readily used for measuring through other types and thicknesses of refractive materials.

  10. Aliphatic polyesters for medical imaging and theranostic applications.

    PubMed

    Nottelet, Benjamin; Darcos, Vincent; Coudane, Jean

    2015-11-01

    Medical imaging is a cornerstone of modern medicine. In that context the development of innovative imaging systems combining biomaterials and contrast agents (CAs)/imaging probes (IPs) for improved diagnostic and theranostic applications focuses intense research efforts. In particular, the classical aliphatic (co)polyesters poly(lactide) (PLA), poly(lactide-co-glycolide) (PLGA) and poly(ɛ-caprolactone) (PCL), attract much attention due to their long track record in the medical field. This review aims therefore at providing a state-of-the-art of polyester-based imaging systems. In a first section a rapid description of the various imaging modalities, including magnetic resonance imaging (MRI), optical imaging, computed tomography (CT), ultrasound (US) and radionuclide imaging (SPECT, PET) will be given. Then, the two main strategies used to combine the CAs/IPs and the polyesters will be discussed. In more detail we will first present the strategies relying on CAs/IPs encapsulation in nanoparticles, micelles, dendrimers or capsules. We will then present chemical modifications of polyesters backbones and/or polyester surfaces to yield macromolecular imaging agents. Finally, opportunities offered by these innovative systems will be illustrated with some recent examples in the fields of cell labeling, diagnostic or theranostic applications and medical devices.

  11. [The application of X-ray imaging in forensic medicine].

    PubMed

    Kučerová, Stěpánka; Safr, Miroslav; Ublová, Michaela; Urbanová, Petra; Hejna, Petr

    2014-07-01

    X-ray is the most common, basic and essential imaging method used in forensic medicine. It serves to display and localize the foreign objects in the body and helps to detect various traumatic and pathological changes. X-ray imaging is valuable in anthropological assessment of an individual. X-ray allows non-invasive evaluation of important findings before the autopsy and thus selection of the optimal strategy for dissection. Basic indications for postmortem X-ray imaging in forensic medicine include gunshot and explosive fatalities (identification and localization of projectiles or other components of ammunition, visualization of secondary missiles), sharp force injuries (air embolism, identification of the weapon) and motor vehicle related deaths. The method is also helpful for complex injury evaluation in abused victims or in persons where abuse is suspected. Finally, X-ray imaging still remains the gold standard method for identification of unknown deceased. With time modern imaging methods, especially computed tomography and magnetic resonance imaging, are more and more applied in forensic medicine. Their application extends possibilities of the visualization the bony structures toward a more detailed imaging of soft tissues and internal organs. The application of modern imaging methods in postmortem body investigation is known as digital or virtual autopsy. At present digital postmortem imaging is considered as a bloodless alternative to the conventional autopsy.

  12. Detecting content adaptive scaling of images for forensic applications

    NASA Astrophysics Data System (ADS)

    Fillion, Claude; Sharma, Gaurav

    2010-01-01

    Content-aware resizing methods have recently been developed, among which, seam-carving has achieved the most widespread use. Seam-carving's versatility enables deliberate object removal and benign image resizing, in which perceptually important content is preserved. Both types of modifications compromise the utility and validity of the modified images as evidence in legal and journalistic applications. It is therefore desirable that image forensic techniques detect the presence of seam-carving. In this paper we address detection of seam-carving for forensic purposes. As in other forensic applications, we pose the problem of seam-carving detection as the problem of classifying a test image in either of two classes: a) seam-carved or b) non-seam-carved. We adopt a pattern recognition approach in which a set of features is extracted from the test image and then a Support Vector Machine based classifier, trained over a set of images, is utilized to estimate which of the two classes the test image lies in. Based on our study of the seam-carving algorithm, we propose a set of intuitively motivated features for the detection of seam-carving. Our methodology for detection of seam-carving is then evaluated over a test database of images. We demonstrate that the proposed method provides the capability for detecting seam-carving with high accuracy. For images which have been reduced 30% by benign seam-carving, our method provides a classification accuracy of 91%.

  13. Study of x-ray CCD image sensor and application

    NASA Astrophysics Data System (ADS)

    Wang, Shuyun; Li, Tianze

    2008-12-01

    In this paper, we expounded the composing, specialty, parameter, its working process, key techniques and methods for charge coupled devices (CCD) twice value treatment. Disposal process for CCD video signal quantification was expatiated; X-ray image intensifier's constitutes, function of constitutes, coupling technique of X-ray image intensifier and CCD were analyzed. We analyzed two effective methods to reduce the harm to human beings when X-ray was used in the medical image. One was to reduce X-ray's radiation and adopt to intensify the image penetrated by X-ray to gain the same effect. The other was to use the image sensor to transfer the images to the safe area for observation. On this base, a new method was presented that CCD image sensor and X-ray image intensifier were combined organically. A practical medical X-ray photo electricity system was designed which can be used in the records and time of the human's penetrating images. The system was mainly made up with the medical X-ray, X-ray image intensifier, CCD vidicon with high resolution, image processor, display and so on. Its characteristics are: change the invisible X-ray into the visible light image; output the vivid images; short image recording time etc. At the same time we analyzed the main aspects which affect the system's resolution. Medical photo electricity system using X-ray image sensor can reduce the X-ray harm to human sharply when it is used in the medical diagnoses. At last we analyzed and looked forward the system's application in medical engineering and the related fields.

  14. Interferometric Quantum-Nondemolition Single-Photon Detectors

    NASA Technical Reports Server (NTRS)

    Kok, Peter; Lee, Hwang; Dowling, Jonathan

    2007-01-01

    Two interferometric quantum-nondemolition (QND) devices have been proposed: (1) a polarization-independent device and (2) a polarization-preserving device. The prolarization-independent device works on an input state of up to two photons, whereas the polarization-preserving device works on a superposition of vacuum and single- photon states. The overall function of the device would be to probabilistically generate a unique detector output only when its input electromagnetic mode was populated by a single photon, in which case its output mode would also be populated by a single photon. Like other QND devices, the proposed devices are potentially useful for a variety of applications, including such areas of NASA interest as quantum computing, quantum communication, detection of gravity waves, as well as pedagogical demonstrations of the quantum nature of light. Many protocols in quantum computation and quantum communication require the possibility of detecting a photon without destroying it. The only prior single- photon-detecting QND device is based on quantum electrodynamics in a resonant cavity and, as such, it depends on the photon frequency. Moreover, the prior device can distinguish only between one photon and no photon. The proposed interferometric QND devices would not depend on frequency and could distinguish between (a) one photon and (b) zero or two photons. The first proposed device is depicted schematically in Figure 1. The input electromagnetic mode would be a superposition of a zero-, a one-, and a two-photon quantum state. The overall function of the device would be to probabilistically generate a unique detector output only when its input electromagnetic mode was populated by a single photon, in which case its output mode also would be populated by a single photon.

  15. Bayesian image reconstruction: Application to emission tomography

    SciTech Connect

    Nunez, J.; Llacer, J.

    1989-02-01

    In this paper we propose a Maximum a Posteriori (MAP) method of image reconstruction in the Bayesian framework for the Poisson noise case. We use entropy to define the prior probability and likelihood to define the conditional probability. The method uses sharpness parameters which can be theoretically computed or adjusted, allowing us to obtain MAP reconstructions without the problem of the grey'' reconstructions associated with the pre Bayesian reconstructions. We have developed several ways to solve the reconstruction problem and propose a new iterative algorithm which is stable, maintains positivity and converges to feasible images faster than the Maximum Likelihood Estimate method. We have successfully applied the new method to the case of Emission Tomography, both with simulated and real data. 41 refs., 4 figs., 1 tab.

  16. Mass spectrometry imaging: applications to food science.

    PubMed

    Taira, Shu; Uematsu, Kohei; Kaneko, Daisaku; Katano, Hajime

    2014-01-01

    Two-dimensional mass spectrometry (MS) analysis of biological samples by means of what is called MS imaging (MSI) is now being used to analyze analyte distribution because it facilitates determination of the existence (what is it?) and localization (where is it?) of biomolecules. Reconstruction of mass image by target signal is given after two-dimensional MS measurements on a sample section. From only one section, we can understand the existence and localization of many molecules without the need of an antibody or fluorescent reagent. In this review, we introduce the analysis of localization of functional constituents and nutrients in herbal medicine products via MSI. The ginsenosides were mainly distributed in the periderm and the tip region of the root of Panax ginseng. The capsaicin was found to be more dominantly localized in the placenta than the pericarp and seed in Capsicum fruits. We expect MSI will be a useful technique for optical quality assurance.

  17. X-ray imaging for security applications

    NASA Astrophysics Data System (ADS)

    Evans, J. Paul

    2004-01-01

    The X-ray screening of luggage by aviation security personnel may be badly hindered by the lack of visual cues to depth in an image that has been produced by transmitted radiation. Two-dimensional "shadowgraphs" with "organic" and "metallic" objects encoded using two different colors (usually orange and blue) are still in common use. In the context of luggage screening there are no reliable cues to depth present in individual shadowgraph X-ray images. Therefore, the screener is required to convert the 'zero depth resolution' shadowgraph into a three-dimensional mental picture to be able to interpret the relative spatial relationship of the objects under inspection. Consequently, additional cognitive processing is required e.g. integration, inference and memory. However, these processes can lead to serious misinterpretations of the actual physical structure being examined. This paper describes the development of a stereoscopic imaging technique enabling the screener to utilise binocular stereopsis and kinetic depth to enhance their interpretation of the actual nature of the objects under examination. Further work has led to the development of a technique to combine parallax data (to calculate the thickness of a target material) with the results of a basis material subtraction technique to approximate the target's effective atomic number and density. This has been achieved in preliminary experiments with a novel spatially interleaved dual-energy sensor which reduces the number of scintillation elements required by 50% in comparison to conventional sensor configurations.

  18. Global shutter imagers for industrial applications

    NASA Astrophysics Data System (ADS)

    Meynants, G.

    2014-05-01

    Global shutter image sensors offer significant advantages over rolling shutter imagers but their implementation needs careful consideration. Each pixel needs a storage element on which the signal is stored after the exposure period. To cope with low read noise requirements, it is essential that the pixel can still perform correlated double sampling or CDS. This requires a second memory element in the pixel, so that the reset reference level of the sense amplifier can be read before the charge is dumped onto the sense node. An important specification is the parasitic light sensitivity or shutter efficiency of the pixel. This is a measure how insensitive the memory cell in the pixel is to light. Depending on the pixel architecture, this may be especially difficult in combination with backside illumination. Other important pixel performance parameters related to pixel architecture are read noise and dark current. In this paper we will review global shutter pixel architectures, compare their performances and discuss future developments. We discuss the issues related to global shutter pixels for high dynamic range and backside illumination, and how the most advanced CMOS image sensor process technologies can offer new approaches.

  19. Imaging sonar development for mine countermeasure applications

    NASA Astrophysics Data System (ADS)

    Johnson, Bruce

    2002-05-01

    Over the past decade the Office of Naval Research (ONR) has sponsored research to improve the mine countermeasures (MCM) community's ability to detect, classify, reacquire, and identify mines. In the first stage of wide area detection and classification, the single biggest problem is the ability to distinguish mines from clutter with side-scan sonar assets. In the reacquire-identify stage, divers employ a single-beam aural sonar for guidance to close proximity for visual identification of targets. Current sonar research efforts in wide-area search focus on clutter rejection through high-resolution imaging by synthetic aperture processing and cuing from broadband response characteristics. For reacquisition and identification, research has focused on compact, multibeam imagers. ONR's focus on transition from towbodies and divers to numbers of small, unmanned underwater vehicles (UUVs) to improve MCM clearance rates has had a major impact on sensor development as well. The presentation will provide an introduction to the session by providing a brief history of the development of navy imaging sonars, how they are employed, and an overview of the current thrusts that will lead to the next generation of Navy MCM sonars.

  20. Molecular Imaging with MRI: Potential Application in Pancreatic Cancer

    PubMed Central

    Chen, Chen; Wu, Chang Qiang; Chen, Tian Wu; Tang, Meng Yue; Zhang, Xiao Ming

    2015-01-01

    Despite the variety of approaches that have been improved to achieve a good understanding of pancreatic cancer (PC), the prognosis of PC remains poor, and the survival rates are dismal. The lack of early detection and effective interventions is the main reason. Therefore, considerable ongoing efforts aimed at identifying early PC are currently being pursued using a variety of methods. In recent years, the development of molecular imaging has made the specific targeting of PC in the early stage possible. Molecular imaging seeks to directly visualize, characterize, and measure biological processes at the molecular and cellular levels. Among different imaging technologies, the magnetic resonance (MR) molecular imaging has potential in this regard because it facilitates noninvasive, target-specific imaging of PC. This topic is reviewed in terms of the contrast agents for MR molecular imaging, the biomarkers related to PC, targeted molecular probes for MRI, and the application of MRI in the diagnosis of PC. PMID:26579537

  1. Applications of dual energy computed tomography in abdominal imaging.

    PubMed

    Lestra, T; Mulé, S; Millet, I; Carsin-Vu, A; Taourel, P; Hoeffel, C

    2016-06-01

    Dual energy computed tomography (CT) is an imaging technique based on data acquisition at two different energy settings. Recent advances in CT have allowed data acquisition and almost simultaneously analysis of two spectra of X-rays at different energy levels resulting in novel developments in the field of abdominal imaging. This technique is widely used in cardiovascular imaging, especially for pulmonary embolism work-up but is now also increasingly developed in the field of abdominal imaging. With dual-energy CT it is possible to obtain virtual unenhanced images from monochromatic reconstructions as well as attenuation maps of different elements, thereby improving detection and characterization of a variety of renal, adrenal, hepatic and pancreatic abnormalities. Also, dual-energy CT can provide information regarding urinary calculi composition. This article reviews and illustrates the different applications of dual-energy CT in routine abdominal imaging.

  2. Spatial-scanning hyperspectral imaging probe for bio-imaging applications

    NASA Astrophysics Data System (ADS)

    Lim, Hoong-Ta; Murukeshan, Vadakke Matham

    2016-03-01

    The three common methods to perform hyperspectral imaging are the spatial-scanning, spectral-scanning, and snapshot methods. However, only the spectral-scanning and snapshot methods have been configured to a hyperspectral imaging probe as of today. This paper presents a spatial-scanning (pushbroom) hyperspectral imaging probe, which is realized by integrating a pushbroom hyperspectral imager with an imaging probe. The proposed hyperspectral imaging probe can also function as an endoscopic probe by integrating a custom fabricated image fiber bundle unit. The imaging probe is configured by incorporating a gradient-index lens at the end face of an image fiber bundle that consists of about 50 000 individual fiberlets. The necessary simulations, methodology, and detailed instrumentation aspects that are carried out are explained followed by assessing the developed probe's performance. Resolution test targets such as United States Air Force chart as well as bio-samples such as chicken breast tissue with blood clot are used as test samples for resolution analysis and for performance validation. This system is built on a pushbroom hyperspectral imaging system with a video camera and has the advantage of acquiring information from a large number of spectral bands with selectable region of interest. The advantages of this spatial-scanning hyperspectral imaging probe can be extended to test samples or tissues residing in regions that are difficult to access with potential diagnostic bio-imaging applications.

  3. Surface imaging microscope

    NASA Astrophysics Data System (ADS)

    Rogala, Eric W.; Bankman, Isaac N.

    2008-04-01

    The three-dimensional shapes of microscopic objects are becoming increasingly important for battlespace CBRNE sensing. Potential applications of microscopic 3D shape observations include characterization of biological weapon particles and manufacturing of micromechanical components. Aerosol signatures of stand-off lidar systems, using elastic backscatter or polarization, are dictated by the aerosol particle shapes and sizes that must be well characterized in the lab. A low-cost, fast instrument for 3D surface shape microscopy will be a valuable point sensor for biological particle sensing applications. Both the cost and imaging durations of traditional techniques such as confocal microscopes, atomic force microscopes, and electron scanning microscopes are too high. We investigated the feasibility of a low-cost, fast interferometric technique for imaging the 3D surface shape of microscopic objects at frame rates limited only by the camera in the system. The system operates at two laser wavelengths producing two fringe images collected simultaneously by a digital camera, and a specialized algorithm we developed reconstructs the surface map of the microscopic object. The current implementation assembled to test the concept and develop the new 3D reconstruction algorithm has 0.25 micron resolution in the x and y directions, and about 0.1 micron accuracy in the z direction, as tested on a microscopic glass test object manufactured with etching techniques. We describe the interferometric instrument, present the reconstruction algorithm, and discuss further development.

  4. Focal-Plane Imaging of Crossed Beams in Nonlinear Optics Experiments

    NASA Technical Reports Server (NTRS)

    Bivolaru, Daniel; Herring, G. C.

    2007-01-01

    An application of focal-plane imaging that can be used as a real time diagnostic of beam crossing in various optical techniques is reported. We discuss two specific versions and demonstrate the capability of maximizing system performance with an example in a combined dual-pump coherent anti-Stokes Raman scattering interferometric Rayleigh scattering experiment (CARS-IRS). We find that this imaging diagnostic significantly reduces beam alignment time and loss of CARS-IRS signals due to inadvertent misalignments.

  5. Three-dimensional hydrodynamical simulations of red giant stars: semi-global models for interpreting interferometric observations

    NASA Astrophysics Data System (ADS)

    Chiavassa, A.; Collet, R.; Casagrande, L.; Asplund, M.

    2010-12-01

    Context. Theoretical predictions from models of red giant branch stars are a valuable tool for various applications in astrophysics ranging from galactic chemical evolution to studies of exoplanetary systems. Aims: We use the radiative transfer code Optim3D and realistic 3D radiative-hydrodynamical (RHD) surface convection simulations of red giants to explore the impact of granulation on interferometric observables. We assess how 3D simulations of surface convection can be validated against observations. Methods: We computed intensity maps for the 3D simulation snapshots in two filters, the optical at 5000 ± 300 Å and the K band 2.14 ± 0.26 μm FLUOR filter, corresponding to the wavelength-range of instruments mounted on the CHARA interferometer. From the intensity maps, we constructed images of the stellar disks and account for center-to-limb variations. We then derived interferometric visibility amplitudes and phases. We study their behavior with position angle and wavelength, and compare them with CHARA observations of the red giant star HD 214868. Results: We provide average limb darkening coefficients for different metallicities and wavelengths ranges. We explain prospects for detecting and characterizing granulation and center-to-limb variations of red giant stars with today's interferometers. Regarding interferometric observables, we find that the effect of convective-related surface structures depends on metallicity and surface gravity. We provide theoretical closure-phases that should be incorporated into the analysis of red giant planet companion closure phase signals. We estimate 3D-1D corrections to stellar radii determination: 3D models are ~3.5% smaller to ~1% larger in the optical than 1D, and roughly 0.5 to 1.5% smaller in the infrared. Even if these corrections are small, they are needed to properly set the zero point of effective temperature scale derived by interferometry and to strengthen the confidence of existing red giant catalogs of

  6. Interferometric coupling of the Keck telescopes with single-mode fibers.

    PubMed

    Perrin, G; Woillez, J; Lai, O; Guérin, J; Kotani, T; Wizinowich, P L; Le Mignant, D; Hrynevych, M; Gathright, J; Léna, P; Chaffee, F; Vergnole, S; Delage, L; Reynaud, F; Adamson, A J; Berthod, C; Brient, B; Collin, C; Crétenet, J; Dauny, F; Deléglise, C; Fédou, P; Goeltzenlichter, T; Guyon, O; Hulin, R; Marlot, C; Marteaud, M; Melse, B-T; Nishikawa, J; Reess, J-M; Ridgway, S T; Rigaut, F; Roth, K; Tokunaga, A T; Ziegler, D

    2006-01-13

    Here we report successful interferometric coupling of two large telescopes with single-mode fibers. Interference fringes were obtained in the 2- to 2.3-micrometer wavelength range on the star 107 Herculis by using the two Keck 10-meter telescopes, each feeding their common interferometric focus with 300 meters of single-mode fibers. This experiment demonstrates the potential of fibers for future kilometric arrays of telescopes and is the first step toward the 'OHANA (Optical Hawaiian Array for Nanoradian Astronomy) interferometer at the Mauna Kea observatory in Hawaii. It opens the way to sensitive optical imagers with resolutions below 1 milli-arc second. Our experimental setup can be directly extended to large telescopes separated by many hundreds of meters. PMID:16410516

  7. HD139614: the Interferometric Case for a Group-Ib Pre-Transitional Young Disk

    NASA Technical Reports Server (NTRS)

    Labadie, Lucas; Matter, Alexis; Kreplin, Alexander; Lopez, Bruno; Wolf, Sebastian; Weigelt, Gerd; Ertel, Steve; Berger, Jean-Philippe; Pott, Jorg-Uwe; Danchi, William C.

    2014-01-01

    The Herbig Ae star HD139614 is a group-Ib object, which featureless SED indicates disk flaring and a possible pre-transitional evolutionary stage. We present mid- and near-IR interferometric results collected with MIDI, AMBER and PIONIER with the aim of constraining the spatial structure of the 0.1-10 AU disk region and assess its possible multi-component structure. A two-component disk model composed of an optically thin 2-AU wide inner disk and an outer temperature-gradient disk starting at 5.6 AU reproduces well the observations. This is an additional argument to the idea that group-I HAeBe inner disks could be already in the disk-clearing transient stage. HD139614 will become a prime target for mid-IR interferometric imaging with the second-generation instrument MATISSE of the VLTI.

  8. The Age of Planet Host κ Andromedae Based on Interferometric Observations

    NASA Astrophysics Data System (ADS)

    Jones, Jeremy; White, Russel J.; Quinn, Samuel N.; Baines, Ellyn K.; Boyajian, Tabetha S.; Ireland, Michael; CHARA Team

    2016-01-01

    We present CHARA Array interferometric observations, obtained with the PAVO beam combiner in the optical (~750 nm), of κ Andromedae. This nearby (51.6 pc) B9/A0V star hosts a directly-imaged low mass companion. Observations made at multiple orientations show the star to be oblate (~15%), consistent with its large projected rotational velocity (vsini = 161.6 ± 22.2 km s-1). The interferometric observations, combined with photometry and the vsini are used to constrain an oblate star model of κ And, enabling us to determine its fundamental properties (e.g., average radius, bolometric luminosity, and equatorial velocity). These stellar properties are compared to the predictions of MESA evolution models to determine an age and mass for the star. The best fit model favors a young age for the system (< 100 Myr), which implies that κ And b has a mass around the limit separating planets and brown dwarfs.

  9. BAYESIAN INFERENCE OF POLARIZED COSMIC MICROWAVE BACKGROUND POWER SPECTRA FROM INTERFEROMETRIC DATA

    SciTech Connect

    Karakci, Ata; Korotkov, Andrei; Tucker, Gregory S.; Sutter, P. M.; Wandelt, Benjamin D.; Zhang, Le; Timbie, Peter; Bunn, Emory F.

    2013-01-15

    Detection of B-mode polarization of the cosmic microwave background (CMB) radiation is one of the frontiers of observational cosmology. Because they are an order of magnitude fainter than E-modes, it is quite a challenge to detect B-modes. Having more manageable systematics, interferometers prove to have a substantial advantage over imagers in detecting such faint signals. Here, we present a method for Bayesian inference of power spectra and signal reconstruction from interferometric data of the CMB polarization signal by using the technique of Gibbs sampling. We demonstrate the validity of the method in the flat-sky approximation for a simulation of an interferometric observation on a finite patch with incomplete uv-plane coverage, a finite beam size, and a realistic noise model. With a computational complexity of O(n {sup 3/2}), n being the data size, Gibbs sampling provides an efficient method for analyzing upcoming cosmology observations.

  10. Computational adaptive optics for broadband interferometric tomography of tissues and cells

    NASA Astrophysics Data System (ADS)

    Adie, Steven G.; Mulligan, Jeffrey A.

    2016-03-01

    Adaptive optics (AO) can shape aberrated optical wavefronts to physically restore the constructive interference needed for high-resolution imaging. With access to the complex optical field, however, many functions of optical hardware can be achieved computationally, including focusing and the compensation of optical aberrations to restore the constructive interference required for diffraction-limited imaging performance. Holography, which employs interferometric detection of the complex optical field, was developed based on this connection between hardware and computational image formation, although this link has only recently been exploited for 3D tomographic imaging in scattering biological tissues. This talk will present the underlying imaging science behind computational image formation with optical coherence tomography (OCT) -- a beam-scanned version of broadband digital holography. Analogous to hardware AO (HAO), we demonstrate computational adaptive optics (CAO) and optimization of the computed pupil correction in 'sensorless mode' (Zernike polynomial corrections with feedback from image metrics) or with the use of 'guide-stars' in the sample. We discuss the concept of an 'isotomic volume' as the volumetric extension of the 'isoplanatic patch' introduced in astronomical AO. Recent CAO results and ongoing work is highlighted to point to the potential biomedical impact of computed broadband interferometric tomography. We also discuss the advantages and disadvantages of HAO vs. CAO for the effective shaping of optical wavefronts, and highlight opportunities for hybrid approaches that synergistically combine the unique advantages of hardware and computational methods for rapid volumetric tomography with cellular resolution.

  11. Dual-channel low-coherence interferometry and its application to quantitative phase imaging of fingerprints.

    PubMed

    Gabai, Haniel; Shaked, Natan T

    2012-11-19

    We introduce an off-axis, wide-field, low-coherence and dual-channel interferometric imaging system, which is based on a simple-to-align, common-path interferometer. The system requires no optical-path-difference matching between the interferometric arms in order to obtain interference with low-coherence light source, and is capable of achieving two channels of off-axis interference with high spatial frequency. The two 180°-phase-shifted interferograms are acquired simultaneously using a single digital camera, and processed into a single, noise-reduced and DC-suppressed interferogram. We demonstrate using the proposed system for phase imaging of fingerprint templates. Due to the fact that conventional phase unwrapping algorithms cannot handle the complex and deep surface topography imposed by fingerprint templates, we experimentally implemented two-wavelength phase unwrapping using a supercontinuum laser coupled to acousto-optical tunable filter, together functioning as a low-coherence tunable light source. From the unwrapped phase map, we produced high quality depth profiles of fingerprint templates.

  12. High speed global shutter image sensors for professional applications

    NASA Astrophysics Data System (ADS)

    Wu, Xu; Meynants, Guy

    2015-04-01

    Global shutter imagers expand the use to miscellaneous applications, such as machine vision, 3D imaging, medical imaging, space etc. to eliminate motion artifacts in rolling shutter imagers. A low noise global shutter pixel requires more than one non-light sensitive memory to reduce the read noise. But larger memory area reduces the fill-factor of the pixels. Modern micro-lenses technology can compensate this fill-factor loss. Backside illumination (BSI) is another popular technique to improve the pixel fill-factor. But some pixel architecture may not reach sufficient shutter efficiency with backside illumination. Non-light sensitive memory elements make the fabrication with BSI possible. Machine vision like fast inspection system, medical imaging like 3D medical or scientific applications always ask for high frame rate global shutter image sensors. Thanks to the CMOS technology, fast Analog-to-digital converters (ADCs) can be integrated on chip. Dual correlated double sampling (CDS) on chip ADC with high interface digital data rate reduces the read noise and makes more on-chip operation control. As a result, a global shutter imager with digital interface is a very popular solution for applications with high performance and high frame rate requirements. In this paper we will review the global shutter architectures developed in CMOSIS, discuss their optimization process and compare their performances after fabrication.

  13. Technique of diffusion weighted imaging and its application in stroke

    NASA Astrophysics Data System (ADS)

    Li, Enzhong; Tian, Jie; Han, Ying; Wang, Huifang; Li, Wu; He, Huiguang

    2003-05-01

    To study the application of diffusion weighted imaging and image post processing in the diagnosis of stroke, especially in acute stroke, 205 patients were examined by 1.5 T or 1.0 T MRI scanner and the images such as T1, T2 and diffusion weighted images were obtained. Image post processing was done with "3D Med System" developed by our lab to analyze data and acquire the apparent diffusion coefficient (ADC) map. In acute and subacute stage of stroke, the signal in cerebral infarction areas changed to hyperintensity in T2- and diffusion-weighted images, normal or hypointensity in T1-weighted images. In hyperacute stage, however, the signal was hyperintense just in the diffusion weighted imaes; others were normal. In the chronic stage, the signal in T1- and diffusion-weighted imaging showed hypointensity and hyperintensity in T2 weighted imaging. Because ADC declined obviously in acute and subacute stage of stroke, the lesion area was hypointensity in ADC map. With the development of the disease, ADC gradually recovered and then changed to hyperintensity in ADC map in chronic stage. Using diffusion weighted imaging and ADC mapping can make a diagnosis of stroke, especially in the hyperacute stage of stroke, and can differentiate acute and chronic stroke.

  14. Lateral organic photodetectors for imaging applications

    NASA Astrophysics Data System (ADS)

    Shafique, Umar; Karim, Karim S.

    2011-03-01

    Organic semiconductor detectors have always been in active research interest of researchers due to its low fabrication cost. Vertical organic detectors have been studied in the past but not much of the works have been done on lateral organic detectors. The lateral design has an advantage over the vertical design that it is easy to fabricate and can be easily integrated with the backplane TFT imager circuit. Integrating an organic photodetectors with TFT imager can improve the over all sensitivity of the imager. However the lateral design limits the fill-factor. Here in our work we propose a new bilayered lateral organic photodetectors with Copper-Phthalocyanine (CUPC) as top and Perylene- Tetracarboxylic Bis- Benzimidazole (PTCBI) as the bottom layer organic material. The bottom organic semiconductor layer work as both, charge transport layer and photon absorption layer. The top and bottom layer provides and heterojunction a potential gradient enough to separate the photo generated excitons in to electrons and holes. The incident photons are absorbed in the two layers active layers giving an exciton. These excitons see a potential barrier at the CUPC-PTCBI heterojunction and separated into holes and electrons. The separated electrons are directed by the external applied electric field and thus give a increase in photocurrent. Lateral organic photodetectors are simple to design and have low dark current. The photo-response of these photo detectors is observed approximately three orders higher in magnitude compare able to its dark response. The dual layer has an advantage of tuning the devices for different absorption wavelengths and were observed more stable comparable to vertical devices.

  15. Time-division multiplexing of polarization-insensitive fiber-optic Michelson interferometric sensors

    NASA Astrophysics Data System (ADS)

    Huang, S. C.; Lin, W. W.; Chen, M. H.

    1995-06-01

    A system of time-division multiplexing of polarization-insensitive fiber-optic Michelson interferometric sensors that uses Faraday rotator mirror elements is demonstrated. This system is constructed with conventional low-birefringence single-mode fiber and is able to solve the polarization-fading problem by a combination of Faraday rotator mirrors with unbalanced Michelson interferometers. The system is lead-fiber insensitive and has potentials for practical field applications.

  16. Applications Of Digital Image Acquisition In Anthropometry

    NASA Astrophysics Data System (ADS)

    Woolford, Barbara; Lewis, James L.

    1981-10-01

    Anthropometric data on reach and mobility have traditionally been collected by time consuming and relatively inaccurate manual methods. Three dimensional digital image acquisition promises to radically increase the speed and ease of data collection and analysis. A three-camera video anthropometric system for collecting position, velocity, and force data in real time is under development for the Anthropometric Measurement Laboratory at NASA's Johnson Space Center. The use of a prototype of this system for collecting data on reach capabilities and on lateral stability is described. Two extensions of this system are planned.

  17. Performance assessment of 3D surface imaging technique for medical imaging applications

    NASA Astrophysics Data System (ADS)

    Li, Tuotuo; Geng, Jason; Li, Shidong

    2013-03-01

    Recent development in optical 3D surface imaging technologies provide better ways to digitalize the 3D surface and its motion in real-time. The non-invasive 3D surface imaging approach has great potential for many medical imaging applications, such as motion monitoring of radiotherapy, pre/post evaluation of plastic surgery and dermatology, to name a few. Various commercial 3D surface imaging systems have appeared on the market with different dimension, speed and accuracy. For clinical applications, the accuracy, reproducibility and robustness across the widely heterogeneous skin color, tone, texture, shape properties, and ambient lighting is very crucial. Till now, a systematic approach for evaluating the performance of different 3D surface imaging systems still yet exist. In this paper, we present a systematic performance assessment approach to 3D surface imaging system assessment for medical applications. We use this assessment approach to exam a new real-time surface imaging system we developed, dubbed "Neo3D Camera", for image-guided radiotherapy (IGRT). The assessments include accuracy, field of view, coverage, repeatability, speed and sensitivity to environment, texture and color.

  18. Passive shortwave infrared technology and hyperspectral imaging for maritime applications

    NASA Astrophysics Data System (ADS)

    Judd, K. Peter; Waterman, James R.; Nichols, J. M.

    2010-04-01

    We present image data and discuss naval sensing applications of SWIR and Hyperspectral SWIR imaging in littoral and marine environments under various light conditions. These environments prove to be challenging for persistent surveillance applications as light levels may vary over several orders of magnitude within and from scene to scene. Additional difficulties include imaging over long water paths where marine haze and turbulence tend to degrade radiation transmission, and discrimination of low contrast objects under low-light and night imaging. Image data obtained from two separate passive sensor systems, both of which are built around an RVS large format (1280 x 1024) InGaAs FPA with high dynamic range and low noise electronics, are presented. The SWIR camera imager is equipped with a custom 300 mm focal length f/2 narrow field-of-view (6° diagonal) refractive telescope. The Hyperspectral imager has a custom selectable 900/1800 mm focal length telescope with corresponding 1.55°/0.79° field-of-view and fnumbers of 3/6 respectively. The sensor uses 1280 pixels in the spatial direction and a window of 192 are used for the spectral and operates at a nominal frame rate of 120 Hz. To assess field performance of the SWIR/Hyperspectral imagers, comparison is made to output from a scientific grade VNIR camera and two state-of-the-art low-light sensors.

  19. Research on interferometric photonic crystal fiber hydrophone

    NASA Astrophysics Data System (ADS)

    Luo, Hong; Zhang, Zhen-hui; Wang, Fu-yin; Xiong, Shui-dong

    2013-08-01

    Current research on photonic crystal fiber (PCF) for acoustic sensing was focused on the PCF's pressure sensitivity enhancement. However, whether the enhancement of the PCF's pressure sensitivity can be actually realized is still controversial. Practical hydrophone, utilizing PCFs, to manifest its superior sensitivity to normal single mode fibers (SMFs) for acoustic sensing, should be made. Account to this point of view, actual hydrophone was fabricated. Index guiding PCF was used, the fiber core is solid silicon dioxide (SiO2), and the cladding is SiO2 filled with lots of periodical transverse circular air hollows. The PCF, mounted on an air-backed mandrel for structural sensitivity enhancement, was used as a sensing arm of the fiber Michelson interferometer. The other arm, so called reference arm, was made of SMF. Faraday rotator mirrors (FRM) were spliced in the end of each interferometric arm account for polarization induced phase fading, which is a common scheme in fiber interferometric sensing systems. A similar hydrophone, with all the same structure except that the PCF was exchanged into SMF, was also fabrication to make the contrast. The narrowlinewidth and frequency-tunable optical fiber laser was used to achieve high accuracy optical interferometric measurement. Meanwhile, the phase generated carrier (PGC) modulation-demodulation scheme was adopted to interrogate the measurand signal. Experiment was done by using acoustic standing-wave test apparatus. Linearity characteristics of the two hydrophones were measured at frequency 100Hz, 500Hz, and 1000Hz, experimental results showed that the maximum error of the linearity was 10%, a little larger than the theoretical results. Pressure sensitivities of the PCF hydrophone and the SMF hydrophone were measured using a reference standard PZT hydrophone in the frequency range from 20 Hz to 1600 Hz, the measurement data showed that the sensitivity of the PCF hydrophone was about -162.8 dB re. rad/μPa, with a

  20. Electronic terahertz imaging for security applications

    NASA Astrophysics Data System (ADS)

    Trontelj, J.; Sešek, A.

    2016-02-01

    A sophisticated THz system with 3D imaging and narrow band spectroscopy capability is presented in the paper. The key system components are the THz source, THz detector/mixer array, scanning optics, and the signal processing unit. The system is all electronic and is portable. A battery operation option allows several hours of autonomy. The most important parameters of the THz source are output power, illumination beam size and directivity, frequency modulation range, and maximal modulation frequency. The low phase noise is also a very important parameter. Optimization of these parameters is discussed in the paper. The THz source is all solid state, composed of a phase-locked oscillator, an amplifier, and frequency multipliers. The most important element of the THz system is its sensor, which performs both signal detection and at the same time mixing of the LO signal and received signal from the target. The sensor is antenna coupled nanobolometer fabricated in a linear array of eight pixels. The sensors are suspended in the vacuum to achieve an excellent signal-to-noise ratio. The quadratic characteristic of the nano-bolometer extends over six decades allowing a large dynamic range and very high LO signal levels. The scanning mirror integrated into the system allows imaging of 1024 to 8162 pixels in the x and y dimensions that are expanded to the third dimension with a resolution of few micrometers.

  1. The application of similar image retrieval in electronic commerce.

    PubMed

    Hu, YuPing; Yin, Hua; Han, Dezhi; Yu, Fei

    2014-01-01

    Traditional online shopping platform (OSP), which searches product information by keywords, faces three problems: indirect search mode, large search space, and inaccuracy in search results. For solving these problems, we discuss and research the application of similar image retrieval in electronic commerce. Aiming at improving the network customers' experience and providing merchants with the accuracy of advertising, we design a reasonable and extensive electronic commerce application system, which includes three subsystems: image search display subsystem, image search subsystem, and product information collecting subsystem. This system can provide seamless connection between information platform and OSP, on which consumers can automatically and directly search similar images according to the pictures from information platform. At the same time, it can be used to provide accuracy of internet marketing for enterprises. The experiment shows the efficiency of constructing the system.

  2. The application of similar image retrieval in electronic commerce.

    PubMed

    Hu, YuPing; Yin, Hua; Han, Dezhi; Yu, Fei

    2014-01-01

    Traditional online shopping platform (OSP), which searches product information by keywords, faces three problems: indirect search mode, large search space, and inaccuracy in search results. For solving these problems, we discuss and research the application of similar image retrieval in electronic commerce. Aiming at improving the network customers' experience and providing merchants with the accuracy of advertising, we design a reasonable and extensive electronic commerce application system, which includes three subsystems: image search display subsystem, image search subsystem, and product information collecting subsystem. This system can provide seamless connection between information platform and OSP, on which consumers can automatically and directly search similar images according to the pictures from information platform. At the same time, it can be used to provide accuracy of internet marketing for enterprises. The experiment shows the efficiency of constructing the system. PMID:24883411

  3. The Application of Similar Image Retrieval in Electronic Commerce

    PubMed Central

    Hu, YuPing; Yin, Hua; Han, Dezhi; Yu, Fei

    2014-01-01

    Traditional online shopping platform (OSP), which searches product information by keywords, faces three problems: indirect search mode, large search space, and inaccuracy in search results. For solving these problems, we discuss and research the application of similar image retrieval in electronic commerce. Aiming at improving the network customers' experience and providing merchants with the accuracy of advertising, we design a reasonable and extensive electronic commerce application system, which includes three subsystems: image search display subsystem, image search subsystem, and product information collecting subsystem. This system can provide seamless connection between information platform and OSP, on which consumers can automatically and directly search similar images according to the pictures from information platform. At the same time, it can be used to provide accuracy of internet marketing for enterprises. The experiment shows the efficiency of constructing the system. PMID:24883411

  4. A hyperspectral image analysis workbench for environmental science applications

    SciTech Connect

    Christiansen, J.H.; Zawada, D.G.; Simunich, K.L.; Slater, J.C.

    1992-10-01

    A significant challenge to the information sciences is to provide more powerful and accessible means to exploit the enormous wealth of data available from high-resolution imaging spectrometry, or ``hyperspectral`` imagery, for analysis, for mapping purposes, and for input to environmental modeling applications. As an initial response to this challenge, Argonne`s Advanced Computer Applications Center has developed a workstation-based prototype software workbench which employs Al techniques and other advanced approaches to deduce surface characteristics and extract features from the hyperspectral images. Among its current capabilities, the prototype system can classify pixels by abstract surface type. The classification process employs neural network analysis of inputs which include pixel spectra and a variety of processed image metrics, including image ``texture spectra`` derived from fractal signatures computed for subimage tiles at each wavelength.

  5. A hyperspectral image analysis workbench for environmental science applications

    SciTech Connect

    Christiansen, J.H.; Zawada, D.G.; Simunich, K.L.; Slater, J.C.

    1992-01-01

    A significant challenge to the information sciences is to provide more powerful and accessible means to exploit the enormous wealth of data available from high-resolution imaging spectrometry, or hyperspectral'' imagery, for analysis, for mapping purposes, and for input to environmental modeling applications. As an initial response to this challenge, Argonne's Advanced Computer Applications Center has developed a workstation-based prototype software workbench which employs Al techniques and other advanced approaches to deduce surface characteristics and extract features from the hyperspectral images. Among its current capabilities, the prototype system can classify pixels by abstract surface type. The classification process employs neural network analysis of inputs which include pixel spectra and a variety of processed image metrics, including image texture spectra'' derived from fractal signatures computed for subimage tiles at each wavelength.

  6. Interferometric processing of C-band SAR data for the improvement of stand age estimation in rubber plantation

    NASA Astrophysics Data System (ADS)

    Trisasongko, Bambang H.; Paull, David J.; Panuju, Dyah R.

    2015-01-01

    Rubber ranks the second largest plantation in Indonesia after oil palm. While oil palm plantations have been exploited mainly by large companies, many rubber plantations are still managed by peasant farmers who maintain its biodiversity. Due to its broad and scattered location, monitoring tropical rubber plantation is a crucial application of active remote sensing. In this paper, the backscatter coefficient of Envisat Advanced Synthetic Aperture Radar (ASAR) is compared to interferometric coherence to study the relationship between stand age and SAR parameters. It is shown that VV polarized C-band SAR achieves its saturation level in plantations aged about 5-10 years. Extension of saturation level can be achieved by processing an interferometric pair of ASAR data, which results in interferometric coherence. In this paper, coherence can take up to 20 years stand age to achieve prior to saturation. Since stand age is highly related to biomass, this finding argues that the biomass can be best estimated using coherence.

  7. VCSELs for interferometric readout of MEMS sensors

    NASA Astrophysics Data System (ADS)

    Serkland, Darwin K.; Geib, Kent M.; Peake, Gregory M.; Keeler, Gordon A.; Shaw, Michael J.; Baker, Michael S.; Okandan, Murat

    2016-03-01

    We report on the development of single-frequency VCSELs (vertical-cavity surface-emitting lasers) for sensing the position of a moving MEMS (micro-electro-mechanical system) object with resolution much less than 1nm. Position measurement is the basis of many different types of MEMS sensors, including accelerometers, gyroscopes, and pressure sensors. Typically, by switching from a traditional capacitive electronic readout to an interferometric optical readout, the resolution can be improved by an order of magnitude with a corresponding improvement in MEMS sensor performance. Because the VCSEL wavelength determines the scale of the position measurement, laser wavelength (frequency) stability is desirable. This paper discusses the impact of VCSEL amplitude and frequency noise on the position measurement.

  8. Four Station Interferometric Radar Observations of Mars

    NASA Technical Reports Server (NTRS)

    Larsen, K. W.; Jurgens, R. F.; Arvidson, R. E.; Slade, M. A.; Haldemann, A. F.

    2002-01-01

    Planetary targets have been observed with radar since the late 1950s when it was first used for ranging experiments with the Moon. As telescope size and power increased, it became possible to observe more distant targets (Venus, Mars, and the outer satellites). Inherent to radar observations is the uncertainty as to the source of the reflection, there being two points where range and Doppler rings intersect on a sphere. The use of interferometric methods, first used on the moon with two stations and later on Venus and Mars, solved this problem. We extend the method through the addition of a fourth receiving telescope (thus doubling the number of projected baselines) and integration of the newly available Mars Orbiter Laser Altimeter (MOLA) topographic datasets.

  9. The Space Infrared Interferometric Telescope (SPIRIT)

    NASA Technical Reports Server (NTRS)

    Rinehart, Stephen

    2007-01-01

    The Space Infrared Interferometric Telescope (SPIRIT) is a candidate NASA Origins Probe Mission. SPIRIT is a two-telescope Michelson interferometer covering wavelengths from 25-400 microns, providing simultaneously high spectral resolution and high angular resolution. With comparable sensitivity to Spitzer, but two orders of magnitude improvement in angular resolution, SPIRIT will enable us to address a wide array of compelling scientific questions, including how planetary systems form in disks and how new planets interact with the disk. Further, SPIRIT will lay the technological groundwork for an array of future interferometry missions with ambitious scientific goals, including the Terrestrial Planet Finder Interferometer / Darwin, and the Submillimeter Probe of the Evolution of Cosmic Structure.

  10. A comparison of interferometric SAR antenna options

    NASA Astrophysics Data System (ADS)

    Doerry, A. W.; Bickel, D. L.

    2013-05-01

    Interferometric Synthetic Aperture Radar (IFSAR or InSAR) uses multiple antenna phase centers to ultimately measure target scene elevation. Its ability to do so depends on the antenna configuration, and how the multiple phase centers are employed. We examine several different dual-phase-center antenna configurations and modalities, including a conventional arrangement where a dedicated antenna is used to transmit and receive with another to receive only, a configuration where transmit and receive operations are ping-ponged between phase centers, a monopulse configuration, and an orthogonal waveform configuration. Our figure of merit is the RMS height noise in the elevation estimation. We show that a monopulse configuration is equivalent to the ping-pong scheme, and both offer an advantage over the conventional arrangement. The orthogonal waveform offers the best potential performance, if sufficient isolation can be achieved.

  11. Interferometric atmospheric refractive-index environmental monitor.

    PubMed

    Ludman, J E; Ludman, J J; Callahan, H; Caulfield, H J; Watt, D; Sampson, J L; Robinson, J; Davis, S; Hunt, A

    1995-06-20

    Long, open-path, outdoor interferometric measurement of the index of refraction as a function of wavelength (spectral refractivity) requires a number of innovations. These include active compensation for vibration and turbulence. The use of electronic compensation produces an electronic signal that is ideal for extracting data. This allows the appropriate interpretation of those data and the systematic and fast scanning of the spectrum by the use of bandwidths that are intermediate between lasers (narrow bandwidth) and white light (broad bandwidth). An Environmental Interferometer that incorporates these features should be extremely valuable in both pollutant detection and pollutant identification. Spectral refractivity measurements complement the information available from spectral absorption instruments (e.g., a Fourier-transform infrared spectrometer). The Environmental Interferometer currently uses an electronic compensating device with a 1-kHz response time, and therefore rapid spectral scans are feasibe so that it is possible to monitor the time evolution of pollutant events.

  12. Tangential velocity measurement using interferometric MTI radar

    DOEpatents

    Doerry, Armin W.; Mileshosky, Brian P.; Bickel, Douglas L.

    2006-01-03

    Radar systems use time delay measurements between a transmitted signal and its echo to calculate range to a target. Ranges that change with time cause a Doppler offset in phase and frequency of the echo. Consequently, the closing velocity between target and radar can be measured by measuring the Doppler offset of the echo. The closing velocity is also known as radial velocity, or line-of-sight velocity. Doppler frequency is measured in a pulse-Doppler radar as a linear phase shift over a set of radar pulses during some Coherent Processing Interval (CPI). An Interferometric Moving Target Indicator (MTI) radar can be used to measure the tangential velocity component of a moving target. Multiple baselines, along with the conventional radial velocity measurement, allow estimating the true 3-D velocity of a target.

  13. 3D Winding Number: Theory and Application to Medical Imaging

    PubMed Central

    Becciu, Alessandro; Fuster, Andrea; Pottek, Mark; van den Heuvel, Bart; ter Haar Romeny, Bart; van Assen, Hans

    2011-01-01

    We develop a new formulation, mathematically elegant, to detect critical points of 3D scalar images. It is based on a topological number, which is the generalization to three dimensions of the 2D winding number. We illustrate our method by considering three different biomedical applications, namely, detection and counting of ovarian follicles and neuronal cells and estimation of cardiac motion from tagged MR images. Qualitative and quantitative evaluation emphasizes the reliability of the results. PMID:21317978

  14. Advanced technologies for remote sensing imaging applications

    SciTech Connect

    Wood, L.L.

    1993-06-07

    Generating and returning imagery from great distances has been generally associated with national security activities, with emphasis on reliability of system operation. (While the introduction of such capabilities was usually characterized by high levels of innovation, the evolution of such systems has followed the classical track of proliferation of ``standardized items`` expressing ever more incremental technological advances.) Recent focusing of interest on the use of remote imaging systems for commercial and scientific purposes can be expected to induce comparatively rapid advances along the axes of efficiency and technological sophistication, respectively. This paper reviews the most basic reasons for expecting the next decade of advances to dwarf the impressive accomplishments of the past ten years. The impact of these advances clearly will be felt in all major areas of large-scale human endeavor, commercial, military and scientific.

  15. An imaging spectrometer for microgravity application

    NASA Technical Reports Server (NTRS)

    Wong, Wallace K.

    1995-01-01

    Flame structure is the result of complex interaction of mechanisms operating in both unwanted fires and controlled combustion systems. The scientific study of gas-jet diffusion flames in reduced-gravity environment is of interest because the effects of buoyancy on flow entrainment and acceleration are lessened. Measurements of flames have been restricted to cinematography, thermocouples, and radiometers. SSG, Inc. is developing an MWIR imaging spectrometer (MIS) for microgravity flame measurements. The device will be delivered to NASA Lewis at the end of this project to demonstrate flame measurements in the laboratory. With proper modifications, the MIS can be used to monitor a gas-jet flame under microgravity on a NASA Learjet or DC-9.

  16. Applications of cell imaging in Salmonella research.

    PubMed

    Perrett, Charlotte A; Jepson, Mark A

    2007-01-01

    Salmonella enterica is a Gram-negative enteropathogen that can cause localized infections, typically resulting in gastroenteritis, or systemic infection, e.g., typhoid fever, in both humans and warm-blooded animals. Understanding the mechanisms by which Salmonella induce disease has been the focus of intensive research. This has revealed that Salmonella invasion requires dynamic cross-talk between the microbe and host cells, in which bacterial adherence rapidly leads to a complex sequence of cellular responses initiated by proteins translocated into the host cell by a type III secretion system (T3SS). Once these Salmonella-induced responses have resulted in bacterial invasion, proteins translocated by a second T3SS initiate further modulation of cellular activities to enable survival and replication of the invading pathogen. These processes contribute to Salmonella entry into the host and the clinical symptoms of gastrointestinal and systemic infection. Elucidation of the complex and highly dynamic pathogen-host interactions ultimately requires analysis at the level of single cells and single infection events. To achieve this goal, researchers have applied a diverse range of microscopical methods to examine Salmonella infection in models ranging from whole animal to isolated cells and simple eukaryotic organisms. For example, electron microscopy and confocal microscopy can reveal the juxtaposition of Salmonella, its products, and cellular components at high resolution. Simple light microscopy (LM) can also be used to investigate the interaction of bacteria with host cells and has advantages for live cell imaging, which enables detailed analysis of the dynamics of infection and cellular responses. Here we review the use of imaging techniques in Salmonella research and compare the capabilities of different classes of microscope to address specific types of research question. We also provide protocols and notes on several LM techniques routinely used in our own

  17. Recent developments of interferometric wavefront sensing

    NASA Astrophysics Data System (ADS)

    Liu, Dong; Yang, Yongying; Chen, Xiaoyu; Ling, Tong; Zhang, Lei; Bai, Jian; Shen, Yibing

    2015-08-01

    Recent trends of interferometric wavefront sensing tend to focus on high precision, anti-vibration, compact, along with much more involved of electric and computer technology. And the optical principles employed not only limit to interference but also include diffraction, scattering, polarization, etc. In this paper, some selected examples basing on the research works in our group will be given to illustrate the trends mentioned above. To achieve extra high accuracy, phase-shifting point diffraction interferometry (PS-PDI) is believed to be a good candidate as it employs a nearly perfect point diffraction spherical wavefront as the reference and also takes advantage of the high precision of phase-shifting algorithms. Cyclic radial shearing interferometry (C-RSI) successively demonstrate the anti-vibration characteristic and can diagnose transient wavefront with only one single shot by employing a three-mirror common-path configuration and a synchronizing system. In contrast sharply with those early interferometers, interferometers with very compact configuration are more suitable to develop portable wavefront sensing instruments. Cross-grating lateral shearing interferometer (CG-LSI) is a very compact interferometer that adopts a cross-grating of millimeters to produce lateral shearing of the diffraction wave of the test wavefront. Be aware that, computer technique has been used a lot in all of the above interferometers but the non-null annual sub-aperture stitching interferometer (NASSI) for general aspheric surface testing mostly relies on the computer model of the physical interferometer setup and iterative ray-tracing optimization. The principles of the above mentioned interferometric wavefront sensing methods would be given in detail.

  18. Application of external tracking in ultrasound elasticity imaging

    NASA Astrophysics Data System (ADS)

    Foroughi, Pezhman; Hager, Gregory D.; Wacker, Frank K.; Boctor, Emad M.

    2010-03-01

    Despite the success of ultrasound elasticity imaging (USEI) in medical applications such as diagnosis and screening of breast lesions and prostate cancer, USEI has not been adopted in routine clinical procedures. This is partly caused by the difficulty in acquiring reliable images and interpreting them, the lack of consistency over time, and the dependency of image quality to the expertise of the user. We previously demonstrated the potential of exploiting an external tracker to partially alleviate these issues and enhance the quality of USEI. The tracking data enabled fast and automatic selection of pairs of RF frames used in strain calculation. Here, we expand this method by including new features. The proposed method employs image content to compensate for the limited accuracy of the tracking device. It also combines multiple strain images to improve the quality of the final image. For this purpose, It normalizes the images and determines which images can be combined relying on the tracking information. We have acquired RF frames synchronized with tracking data from livers of pig containing an ablated region and a breast phantom using two different tracking devices; an optical tracker and a less accurate electromagnetic tracker. We present the promising results of the proposed method and investigate the sensitivity of frame selection technique without using the image content to inaccuracies in tracking information.

  19. Performance and application of real-time hyperspectral imaging

    NASA Astrophysics Data System (ADS)

    Dombrowski, Mark S.; Willson, Paul D.; LaBaw, Clayton C.

    1998-10-01

    Hyperspectral imaging is the latest advent in imaging technology, providing the potential to extract information about the objects in a scene that is unavailable to panchromatic imagers. This increased utility, however, comes at the cost of tremendously increased data. The ultimate utility of hyperspectral imagery is in the information that can be gleaned from the spectral dimension, rather than in the hyperspectral imagery itself. To have the broadest range of applications, extraction of this information must occur in real-time. Attempting to produce and exploit complete cubes of hyperspectral imagery at video rates, however, present unique problems for both the imager and the processor, since data rates are scaled by the number of spectral planes in the cube. MIDIS, the Multi-band Identification and Discrimination Imaging Spectroradiometer, allows both real-time here are the major design innovations associated with producing high-speed, high-sensitivity hyperspectral imagers operating in the SWIR and LWIR, and of the electronics capable of handling data rates up to 160 megapixels per second, continuously. Discussion of real-time algorithms capable of exploiting the spectral dimension of the imagery is also included. Beyond design and performance issues associated with producing and processing hyperspectral imagery at such high speeds, this paper also discusses applications of real-time hyperspectral imaging technology. Example imagery includes such problems as detecting counterfeit money, inspecting surfaces, and countering CCD.

  20. On combining image-based and ontological semantic dissimilarities for medical image retrieval applications

    PubMed Central

    Kurtz, Camille; Depeursinge, Adrien; Napel, Sandy; Beaulieu, Christopher F.; Rubin, Daniel L.

    2014-01-01

    Computer-assisted image retrieval applications can assist radiologists by identifying similar images in archives as a means to providing decision support. In the classical case, images are described using low-level features extracted from their contents, and an appropriate distance is used to find the best matches in the feature space. However, using low-level image features to fully capture the visual appearance of diseases is challenging and the semantic gap between these features and the high-level visual concepts in radiology may impair the system performance. To deal with this issue, the use of semantic terms to provide high-level descriptions of radiological image contents has recently been advocated. Nevertheless, most of the existing semantic image retrieval strategies are limited by two factors: they require manual annotation of the images using semantic terms and they ignore the intrinsic visual and semantic relationships between these annotations during the comparison of the images. Based on these considerations, we propose an image retrieval framework based on semantic features that relies on two main strategies: (1) automatic “soft” prediction of ontological terms that describe the image contents from multi-scale Riesz wavelets and (2) retrieval of similar images by evaluating the similarity between their annotations using a new term dissimilarity measure, which takes into account both image-based and ontological term relations. The combination of these strategies provides a means of accurately retrieving similar images in databases based on image annotations and can be considered as a potential solution to the semantic gap problem. We validated this approach in the context of the retrieval of liver lesions from computed tomographic (CT) images and annotated with semantic terms of the RadLex ontology. The relevance of the retrieval results was assessed using two protocols: evaluation relative to a dissimilarity reference standard defined for pairs

  1. Image database generation using image metric constraints: an application within the CALADIOM project

    NASA Astrophysics Data System (ADS)

    Landeau, Stéphane; Dagobert, Tristan

    2006-05-01

    Performance assessment and optimization of ATR systems poses the problem of developing image databases for learning and testing purposes. An automatic IR image database generation technique is presented in this paper. The principle consists in superimposing segmented background, target and mask (bushes for example) from real images, under the constraint of predefined image characterization metrics. Each image is automatically computed according to a specification which defines the metrics levels to reach, such as the local contrast ΔT RSS (NVESD metric), the Signal to Clutter Ratio, or the masking ratio target/mask. An integrated calibrated sensor model simulates the sensor degradations by using the pre and post-filter MTF, and the 3D noise parameters of the camera. The image generation comes with the construction of a ground truth file which indicates all the parameter values defining the image scenario. A large quantity of images can be generated accordingly, leading to a meaningful statistical evaluation. A key feature is that this technique allows to build learning and testing databases with comparable difficulty, in the sense of the chosen image metrics. The theoretical interest of this technique is presented in the paper, compared to the classical ones which use real or simulated data. An application is also presented, within the CALADIOM project (terrestrial target detection with programmable artificial IR retina combined with IR ATR system). Over 38,000 images were processed by this ATR for training and testing, involving seven armored vehicles as targets.

  2. The future of imaging spectroscopy - Prospective technologies and applications

    USGS Publications Warehouse

    Schaepman, M.E.; Green, R.O.; Ungar, S.G.; Curtiss, B.; Boardman, J.; Plaza, A.J.; Gao, B.-C.; Ustin, S.; Kokaly, R.; Miller, J.R.; Jacquemoud, S.; Ben-Dor, E.; Clark, R.; Davis, C.; Dozier, J.; Goodenough, D.G.; Roberts, D.; Swayze, G.; Milton, E.J.; Goetz, A.F.H.

    2006-01-01

    Spectroscopy has existed for more than three centuries now. Nonetheless, significant scientific advances have been achieved. We discuss the history of spectroscopy in relation to emerging technologies and applications. Advanced focal plane arrays, optical design, and intelligent on-board logic are prime prospective technologies. Scalable approaches in pre-processing of imaging spectrometer data will receive additional focus. Finally, we focus on new applications monitoring transitional ecological zones, where human impact and disturbance have highest impact as well as in monitoring changes in our natural resources and environment We conclude that imaging spectroscopy enables mapping of biophysical and biochemical variables of the Earth's surface and atmospheric composition with unprecedented accuracy.

  3. [Diffusion Weighted Magnetic Resonance Imaging and its Application in Ophthalmology].

    PubMed

    Lindner, T; Langner, S; Paul, K; Pohlmann, A; Hadlich, S; Niendorf, T; Jünemann, A; Guthoff, R F; Stachs, O

    2015-12-01

    The value of diffusion-weighted magnet resonance imaging (DWI-MRI) has been demonstrated for an ever growing range of clinical indications. DWI is sensitive to the diffusion of water molecules and probes their random displacement within tissue. DWI provides both qualitative and quantitative information on tissue characteristics, e.g. tissue cellularity. This review provides an overview of diffusion-weighted imaging and its emerging applications in ophthalmology. The basic physics and technical foundations of DWI are introduced. The emerging applications of DWI are surveyed, particularly in diseases of the eye, orbit and optical nerve.

  4. The application of image processing techniques and technology for security and surveillance applications

    NASA Astrophysics Data System (ADS)

    Smith, Moira I.; Hickman, Duncan

    2007-04-01

    The range and scope of EO/IR sensor systems within security and surveillance applications is growing, and this places a corresponding demand on the image processing functionality required to meet the end-users' needs and requirements. Within this paper, the application of different image processing architectures and techniques is reviewed in terms of situational awareness criteria and is illustrated through specific system applications. The concepts and benefits of multimodal and distributed sensor systems are also considered together with the attendant data registration and fusion techniques. Finally, the exploitation of a priori information within the integrated security and surveillance picture is considered from both a processing technology and image display perspective.

  5. Applications of digital image acquisition in anthropometry

    NASA Technical Reports Server (NTRS)

    Woolford, B.; Lewis, J. L.

    1981-01-01

    A description is given of a video kinesimeter, a device for the automatic real-time collection of kinematic and dynamic data. Based on the detection of a single bright spot by three TV cameras, the system provides automatic real-time recording of three-dimensional position and force data. It comprises three cameras, two incandescent lights, a voltage comparator circuit, a central control unit, and a mass storage device. The control unit determines the signal threshold for each camera before testing, sequences the lights, synchronizes and analyzes the scan voltages from the three cameras, digitizes force from a dynamometer, and codes the data for transmission to a floppy disk for recording. Two of the three cameras face each other along the 'X' axis; the third camera, which faces the center of the line between the first two, defines the 'Y' axis. An image from the 'Y' camera and either 'X' camera is necessary for determining the three-dimensional coordinates of the point.

  6. Interferometric methods for measurement of ultrasonic wave velocity: Classification, characteristics and basic defects

    NASA Technical Reports Server (NTRS)

    Kozlowski, Z.

    1974-01-01

    Interferometric methods may be considered to include all methods in which the time necessary for a signal to pass through a medium is determined on the basis of the period of oscillation of which the signal consists, while the distance is determined by noting the coincidence between (1) interference between the measured signal and its reflection and ultrasonic interference, or between another signal serving as a reference and electrical interference in the electronic part of the device. In general, all interferometric methods are relatively simple and permit a high degree of accuracy. Theoretically 48 different variations may be distinguished, about 30 of which are capable of practical application. For liquids, where transverse waves do not exist, the number of possible variations is limited to 40, assuming that absolute velocity measurement is desired.

  7. Practical phase unwrapping of interferometric fringes based on unscented Kalman filter technique.

    PubMed

    Cheng, Zhongtao; Liu, Dong; Yang, Yongying; Ling, Tong; Chen, Xiaoyu; Zhang, Lei; Bai, Jian; Shen, Yibing; Miao, Liang; Huang, Wei

    2015-12-14

    A phase unwrapping algorithm for interferometric fringes based on the unscented Kalman filter (UKF) technique is proposed. The algorithm can bring about accurate phase unwrapping and good noise suppression simultaneously by incorporating the true phase and its derivative in the state vector estimation through the UKF process. Simulations indicate that the proposed algorithm has better accuracy than some widely employed phase unwrapping approaches in the same noise condition. Also, the time consumption of the algorithm is reasonably acceptable. Applications of the algorithm in our different optical interferometer systems are provided to demonstrate its practicability with good performance. We hope this algorithm can be a practical approach that can help to reduce the systematic errors significantly induced by phase unwrapping process for interferometric measurements such as wavefront distortion testing, surface figure testing of optics, etc.

  8. Applications of the Generalized X-ray Diffraction Enhanced Imaging in the Medical Imaging

    NASA Astrophysics Data System (ADS)

    Maksimenko, Anton; Hashimoto, Eiko; Ando, Masami; Sugiyama, Hiroshi

    2007-01-01

    The X-ray Diffraction Enhanced Imaging (DEI) is the analyzer-based X-ray imaging technique which allows extraction of the "pure refraction" and "apparent absorption" contrasts from two images taken on the opposite sides of the rocking curve of the analyzing crystal. The refraction contrast obtained by this method shows many advantages over conventional absorption contrast. It was successfully applied in medicine, technique and other fields of science. However, information provided by the method is rather qualitative than quantitative. This happens because either side of the rocking curve of the analyzer is approximated as a straight line what limits the ranges of applicability and introduces additional error. One can easily overcome this problem considering the rocking curve as is instead of it's Taylor's expansion. This report is dedicated to the application of this idea in medical imaging and especially computed tomography based on the refraction contrast. The results obtained via both methods are presented and compared.

  9. Coded access optical sensor (CAOS) imager and applications

    NASA Astrophysics Data System (ADS)

    Riza, Nabeel A.

    2016-04-01

    Starting in 2001, we proposed and extensively demonstrated (using a DMD: Digital Micromirror Device) an agile pixel Spatial Light Modulator (SLM)-based optical imager based on single pixel photo-detection (also called a single pixel camera) that is suited for operations with both coherent and incoherent light across broad spectral bands. This imager design operates with the agile pixels programmed in a limited SNR operations starring time-multiplexed mode where acquisition of image irradiance (i.e., intensity) data is done one agile pixel at a time across the SLM plane where the incident image radiation is present. Motivated by modern day advances in RF wireless, optical wired communications and electronic signal processing technologies and using our prior-art SLM-based optical imager design, described using a surprisingly simple approach is a new imager design called Coded Access Optical Sensor (CAOS) that has the ability to alleviate some of the key prior imager fundamental limitations. The agile pixel in the CAOS imager can operate in different time-frequency coding modes like Frequency Division Multiple Access (FDMA), Code-Division Multiple Access (CDMA), and Time Division Multiple Access (TDMA). Data from a first CAOS camera demonstration is described along with novel designs of CAOS-based optical instruments for various applications.

  10. PAU-SA: A Synthetic Aperture Interferometric Radiometer Test Bed for Potential Improvements in Future Missions

    PubMed Central

    Ramos-Perez, Isaac; Camps, Adriano; Bosch-Lluis, Xavi; Rodriguez-Alvarez, Nereida; Valencia-Domènech, Enric; Park, Hyuk; Forte, Giuseppe; Vall-llosera, Merce

    2012-01-01

    The Soil Moisture and Ocean Salinity (SMOS) mission is an Earth Explorer Opportunity mission from the European Space Agency (ESA). Its goal is to produce global maps of soil moisture and ocean salinity using the Microwave Imaging Radiometer by Aperture Synthesis (MIRAS). The purpose of the Passive Advanced Unit Synthetic Aperture (PAU-SA) instrument is to study and test some potential improvements that could eventually be implemented in future missions using interferometric radiometers such as the Geoestacionary Atmosferic Sounder (GAS), the Precipitation and All-weather Temperature and Humidity (PATH) and the Geostationary Interferometric Microwave Sounder (GIMS). Both MIRAS and PAU-SA are Y-shaped arrays with uniformly distributed antennas, but the receiver topology and the processing unit are quite different. The purpose of this work is to identify the elements in the MIRAS's design susceptible of improvement and apply them in the PAU-SA instrument demonstrator, to test them in view of these future interferometric radiometer missions. PMID:22969371

  11. Temporal Coherence as an Estimate of Decorrelation Time of SAR Interferometric Measurements

    NASA Astrophysics Data System (ADS)

    Foumelis, Michael

    2014-05-01

    Following a plethora of validations and demonstrations Interferometric SAR (InSAR) has been established as a mature space geodetic technique for providing valuable insights for various phenomena related to geohazards. One of the main advantages of space borne SAR systems with respect to GNSS is the continuous spatial coverage. However, the impact of temporal decorrelation especially in repeat-pass interferometry has been observed during the historical development of InSAR applications. Interferometric coherence is considered as the expression of temporal decorrelation. It is understood that interferometric coherence decreases with time between SAR acquisitions because of changes in surface reflectivity, reducing the accuracy and spatial coverage of SAR phase measurements. This is an intrinsic characteristic of the design of SAR systems that has a significant contribution at longer time scales. Since the majority of geohazards rely on long term observation scenarios, the effect of temporal decorrelation is evident as coherence becomes dominated by temporal changes. Although in the past there was not sufficient amount of SAR data to extract robust statistical metrics, in the present study it is demonstrated that tailored analysis of interferometric coherence by exploiting the large archive of SAR data available by the European Space Agency (ESA), enables the accurate quantification of temporal decorrelation. A methodology to translate the observed rate of coherence loss into decorrelation times over a volcanic landscape is the subject treated in this study. Specifically, a sensitivity analysis based on a large data stack of interferometric pairs in order to quantitatively estimate at a pixel level the time beyond which each interferometric phase becomes practically unusable is presented. The estimation and mapping of the spatial distribution of the temporal decorrelation times in an area without a necessary a priori knowledge of its surface characteristics is a

  12. Imaging requirements for medical applications of additive manufacturing.

    PubMed

    Huotilainen, Eero; Paloheimo, Markku; Salmi, Mika; Paloheimo, Kaija-Stiina; Björkstrand, Roy; Tuomi, Jukka; Markkola, Antti; Mäkitie, Antti

    2014-02-01

    Additive manufacturing (AM), formerly known as rapid prototyping, is steadily shifting its focus from industrial prototyping to medical applications as AM processes, bioadaptive materials, and medical imaging technologies develop, and the benefits of the techniques gain wider knowledge among clinicians. This article gives an overview of the main requirements for medical imaging affected by needs of AM, as well as provides a brief literature review from existing clinical cases concentrating especially on the kind of radiology they required. As an example application, a pair of CT images of the facial skull base was turned into 3D models in order to illustrate the significance of suitable imaging parameters. Additionally, the model was printed into a preoperative medical model with a popular AM device. Successful clinical cases of AM are recognized to rely heavily on efficient collaboration between various disciplines - notably operating surgeons, radiologists, and engineers. The single main requirement separating tangible model creation from traditional imaging objectives such as diagnostics and preoperative planning is the increased need for anatomical accuracy in all three spatial dimensions, but depending on the application, other specific requirements may be present as well. This article essentially intends to narrow the potential communication gap between radiologists and engineers who work with projects involving AM by showcasing the overlap between the two disciplines.

  13. Addressing the challenges of thermal imaging for firefighting applications

    NASA Astrophysics Data System (ADS)

    Kostrzewa, Joseph; Meyer, William H.; Poe, George; Terre, William A.; Salapow, Thomas M.; Raimondi, John

    2003-09-01

    By providing visibility through smoke and absolute darkness, thermal imaging has the potential to radically improve the effectiveness and safety of the modern firefighter. Some of the roles of thermal imaging are assisting in detection of victims; navigating through dark, smoke-filled structures; detecting indications of imminent flash-over/roll-over; identifying and attacking the seat and extension of a fire; and surveying for lingering hot spots after a fire is nearly extinguished. In many respects, thermal imaging is ideally suited for these functions. However, firefighting applications present the infrared community some unique and challenging design constraints, not the least of which is an operating environment that is in some ways more harsh than most aerospace applications. While many previous papers have described the benefits of thermal imaging for firefighters, this paper describes several specific engineering challenges of this application. These include large ambient temperature range, rapidly changing scene dynamics, extreme demands on AGC, and large dynamic range requirements. This paper describes these and other challenges in detail and explains how they were addressed and overcome in the design of Evolution 5000, a state-of-the-art thermal imager designed and manufactured by Mine Safety Appliances (MSA) using Indigo System"s Omega miniature uncooled camera core.

  14. Dual plasmonic gold nanoparticles for multispectral photoacoustic imaging application

    NASA Astrophysics Data System (ADS)

    Raghavan, Vijay; Subhash, Hrebesh; Breathnach, Aedán.; Leahy, Martin; Dockery, Peter; Olivo, Malini

    2014-03-01

    Nanoparticle contrast agents for molecular targeted imaging have widespread interest in diagnostic applications with cellular resolution, specificity and selectivity for visualization and assessment of various disease processes. Of particular interest is gold nanoparticle owing to its tunability of the surface plasmon resonance (SPR) and its relative inertness. Here we present the synthesis of anisotropic multi-branched star shaped gold nanoparticles exhibiting dual-band plasmon absorption peaks and its application as a contrast agent for multispectral photoacoustic imaging. The transverse plasmon absorption peak of the synthesised dual plasmonic gold nanostar (DPGNS) was around 700 nm and that of longitudinal plasmon absorption in the longer wavelength region around 1050-1150 nm. Unlike most reported PA contrast agent with surface plasmon absorption in the range of 700 to 800 nm showing moderate tissue penetration, 1050-1200 nm range lies in the farther region of the optical window of biological tissue where scattering and the intrinsic optical extinction of endogenous chromophores is at its minimum. We also present a proof of principle demonstration of DPGNS as contrast agent for multispectral photoacoustic animal imaging. Our results show that DPGNS are promising for PA imaging with extended-depth imaging applications.

  15. Research-grade CMOS image sensors for remote sensing applications

    NASA Astrophysics Data System (ADS)

    Saint-Pe, Olivier; Tulet, Michel; Davancens, Robert; Larnaudie, Franck; Magnan, Pierre; Martin-Gonthier, Philippe; Corbiere, Franck; Belliot, Pierre; Estribeau, Magali

    2004-11-01

    Imaging detectors are key elements for optical instruments and sensors on board space missions dedicated to Earth observation (high resolution imaging, atmosphere spectroscopy...), Solar System exploration (micro cameras, guidance for autonomous vehicle...) and Universe observation (space telescope focal planes, guiding sensors...). This market has been dominated by CCD technology for long. Since the mid-90s, CMOS Image Sensors (CIS) have been competing with CCDs for consumer domains (webcams, cell phones, digital cameras...). Featuring significant advantages over CCD sensors for space applications (lower power consumption, smaller system size, better radiations behaviour...), CMOS technology is also expanding in this field, justifying specific R&D and development programs funded by national and European space agencies (mainly CNES, DGA and ESA). All along the 90s and thanks to their increasingly improving performances, CIS have started to be successfully used for more and more demanding space applications, from vision and control functions requiring low-level performances to guidance applications requiring medium-level performances. Recent technology improvements have made possible the manufacturing of research-grade CIS that are able to compete with CCDs in the high-performances arena. After an introduction outlining the growing interest of optical instruments designers for CMOS image sensors, this paper will present the existing and foreseen ways to reach high-level electro-optics performances for CIS. The developments and performances of CIS prototypes built using an imaging CMOS process will be presented in the corresponding section.

  16. Research-grade CMOS image sensors for demanding space applications

    NASA Astrophysics Data System (ADS)

    Saint-Pé, Olivier; Tulet, Michel; Davancens, Robert; Larnaudie, Franck; Magnan, Pierre; Corbière, Franck; Martin-Gonthier, Philippe; Belliot, Pierre

    2004-06-01

    Imaging detectors are key elements for optical instruments and sensors on board space missions dedicated to Earth observation (high resolution imaging, atmosphere spectroscopy...), Solar System exploration (micro cameras, guidance for autonomous vehicle...) and Universe observation (space telescope focal planes, guiding sensors...). This market has been dominated by CCD technology for long. Since the mid-90s, CMOS Image Sensors (CIS) have been competing with CCDs for more and more consumer domains (webcams, cell phones, digital cameras...). Featuring significant advantages over CCD sensors for space applications (lower power consumption, smaller system size, better radiations behaviour...), CMOS technology is also expanding in this field, justifying specific R&D and development programs funded by national and European space agencies (mainly CNES, DGA, and ESA). All along the 90s and thanks to their increasingly improving performances, CIS have started to be successfully used for more and more demanding applications, from vision and control functions requiring low-level performances to guidance applications requiring medium-level performances. Recent technology improvements have made possible the manufacturing of research-grade CIS that are able to compete with CCDs in the high-performances arena. After an introduction outlining the growing interest of optical instruments designers for CMOS image sensors, this talk will present the existing and foreseen ways to reach high-level electro-optics performances for CIS. The developments of CIS prototypes built using an imaging CMOS process and of devices based on improved designs will be presented.

  17. Imaging systems for biomedical applications. Final report

    SciTech Connect

    Radparvar, M.

    1995-06-06

    Many of the activities of the human body manifest themselves by the presence of a very weak magnetic field outside the body, a field that is so weak that an ultra-sensitive magnetic sensor is needed for specific biomagnetic measurements. Superconducting QUantum Interference Devices (SQUIDs) are extremely sensitive detectors of magnetic flux and have been used extensively to detect the human magnetocardiogram, and magnetoencephalogram. and other biomagnetic signals. In order to utilize a SQUID as a magnetometer, its transfer characteristics should be linearized. This linearization requires extensive peripheral electronics, thus limiting the number of SQUID magnetometer channels in a practical system. The proposed digital SQUID integrates the processing circuitry on the same cryogenic chip as the SQUID magnetometer and eliminates the sophisticated peripheral electronics. Such a system is compact and cost effective, and requires minimal support electronics. Under a DOE-sponsored SBIR program, we designed, simulated, laid out, fabricated, evaluated, and demonstrated a digital SQUID magnetometer. This report summarizes the accomplishments under this program and clearly demonstrates that all of the tasks proposed in the phase II application were successfully completed with confirmed experimental results.

  18. a Review of Hyperspectral Imaging in Close Range Applications

    NASA Astrophysics Data System (ADS)

    Kurz, T. H.; Buckley, S. J.

    2016-06-01

    Hyperspectral imaging is an established method for material mapping, which has been conventionally applied from airborne and spaceborne platforms for a range of applications, including mineral and vegetation mapping, change detection and environmental studies. The main advantage of lightweight hyperspectral imagers lies in the flexibility to deploy them from various platforms (terrestrial imaging and from unmanned aerial vehicles; UAVs), as well as the high spectral resolution to cover an expanding wavelength range. In addition, spatial resolution allows object sampling distances from micrometres to tens of centimetres - complementary to conventional nadir-looking systems. When this new type of imaging device was initially released, few instruments were available and the applicability and potential of the method was restricted. Today, a wider range of instruments, with a range of specifications, is available, with significant improvements over the first generation of technology. In this contribution, the state-of-the-art of hyperspectral imaging will be reviewed from a close range measurement perspective, highlighting how the method supplements geometric modelling techniques. An overview of the processing workflow, adjusted to the more complex close range imaging scenario will be given. This includes the integration with 3D laser scanning and photogrammetric models to provide a geometric framework and real world coordinate system for the hyperspectral imagery.

  19. Passive interferometric symmetries of multimode Gaussian pure states

    NASA Astrophysics Data System (ADS)

    Gabay, Natasha; Menicucci, Nicolas C.

    2016-05-01

    As large-scale multimode Gaussian states begin to become accessible in the laboratory, their representation and analysis become a useful topic of research in their own right. The graphical calculus for Gaussian pure states provides powerful tools for their representation, while this work presents a useful tool for their analysis: passive interferometric (i.e., number-conserving) symmetries. Here we show that these symmetries of multimode Gaussian states simplify calculations in measurement-based quantum computing and provide constructive tools for engineering large-scale harmonic systems with specific physical properties, and we provide a general mathematical framework for deriving them. Such symmetries are generated by linear combinations of operators expressed in the Schwinger representation of U (2 ) , called nullifiers because the Gaussian state in question is a zero eigenstate of them. This general framework is shown to have applications in the noise analysis of continuous-various cluster states and is expected to have additional applications in future work with large-scale multimode Gaussian states.

  20. Techniques for Field Application of Lingual Ultrasound Imaging

    ERIC Educational Resources Information Center

    Gick, Bryan; Bird, Sonya; Wilson, Ian

    2005-01-01

    Techniques are discussed for using ultrasound for lingual imaging in field-related applications. The greatest challenges we have faced distinguishing the field setting from the laboratory setting are the lack of controlled head/transducer movement, and the related issue of tissue compression. Two experiments are reported. First, a pilot study…

  1. Perspectives on Imaging: Advanced Applications. Introduction and Overview.

    ERIC Educational Resources Information Center

    Lynch, Clifford A.; Lunin, Lois F.

    1991-01-01

    Provides an overview of six articles that address relationships between electronic imaging technology and information science. Articles discuss the areas of technology; applications in the fields of visual arts, medicine, and textile history; conceptual foundations; and future visions, including work in virtual reality and cyberspace. (LRW)

  2. Evaluation of the Pentium 4 for imaging applications

    NASA Astrophysics Data System (ADS)

    Grow, Michael S.; Kim, Yongmin

    2001-12-01

    In the past few years, programmable mediaprocessors (e.g., Hitachi/Equator Technologies MAP-CA and Texas Instruments TMS320C6x) have been replacing ASICs and other hardwired components in imaging applications (e.g., medical imaging modalities, machine vision systems, and video conferencing). Due to the high performance requirements of many imaging applications, older general-purpose processors were not suitable for these kinds of applications. For instance, in 1993 the TMS320C80 was about 50 times faster than the Intel 486 processor. However, recent advances in the architecture and instruction sets of general-purpose processors have closed the gap significantly in performance between these processors and programmable mediaprocessors. For example, the MMX, SSE, and SSE2 extensions to the Pentium 4 instruction set give the Pentium 4 a legitimate multimedia instruction set that is comparable to the instruction sets found in mediaprocessors, thus further blurring the boundary between general-purpose processors and mediaprocessors. The combination of the instruction set extensions and a new architecture that supports very high clock frequencies give the Pentium 4 performance in imaging functions comparable to high performance mediaprocessors and thereby make the Pentium 4 a candidate for applications where its large size, high cost, and high power consumption are not overriding issues.

  3. A Low-Cost Imaging System for Aerial Applicators

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Agricultural aircraft provide a readily available and versatile platform for airborne remote sensing. Although various airborne imaging systems are being used for research and commercial applications, most of these systems are either too expensive or too complex to be of practical use for aerial app...

  4. Fundamental developments in infrared spectroscopic imaging for biomedical applications.

    PubMed

    Pilling, Michael; Gardner, Peter

    2016-04-01

    Infrared chemical imaging is a rapidly emerging field with new advances in instrumentation, data acquisition and data analysis. These developments have had significant impact in biomedical applications and numerous studies have now shown that this technology offers great promise for the improved diagnosis of the diseased state. Relying on purely biochemical signatures rather than contrast from exogenous dyes and stains, infrared chemical imaging has the potential to revolutionise histopathology for improved disease diagnosis. In this review we discuss the recent advances in infrared spectroscopic imaging specifically related to spectral histopathology (SHP) and consider the current state of the field. Finally we consider the practical application of SHP for disease diagnosis and consider potential barriers to clinical translation highlighting current directions and the future outlook. PMID:26996636

  5. Applications of nuclear magnetic resonance imaging in process engineering

    NASA Astrophysics Data System (ADS)

    Gladden, Lynn F.; Alexander, Paul

    1996-03-01

    During the past decade, the application of nuclear magnetic resonance (NMR) imaging techniques to problems of relevance to the process industries has been identified. The particular strengths of NMR techniques are their ability to distinguish between different chemical species and to yield information simultaneously on the structure, concentration distribution and flow processes occurring within a given process unit. In this paper, examples of specific applications in the areas of materials and food processing, transport in reactors and two-phase flow are discussed. One specific study, that of the internal structure of a packed column, is considered in detail. This example is reported to illustrate the extent of new, quantitative information of generic importance to many processing operations that can be obtained using NMR imaging in combination with image analysis.

  6. Ultrasensitive interferometric on-chip microscopy of transparent objects.

    PubMed

    Terborg, Roland A; Pello, Josselin; Mannelli, Ilaria; Torres, Juan P; Pruneri, Valerio

    2016-06-01

    Light microscopes can detect objects through several physical processes, such as scattering, absorption, and reflection. In transparent objects, these mechanisms are often too weak, and interference effects are more suitable to observe the tiny refractive index variations that produce phase shifts. We propose an on-chip microscope design that exploits birefringence in an unconventional geometry. It makes use of two sheared and quasi-overlapped illuminating beams experiencing relative phase shifts when going through the object, and a complementary metal-oxide-semiconductor image sensor array to record the resulting interference pattern. Unlike conventional microscopes, the beams are unfocused, leading to a very large field of view (20 mm(2)) and detection volume (more than 0.5 cm(3)), at the expense of lateral resolution. The high axial sensitivity (<1 nm) achieved using a novel phase-shifting interferometric operation makes the proposed device ideal for examining transparent substrates and reading microarrays of biomarkers. This is demonstrated by detecting nanometer-thick surface modulations on glass and single and double protein layers. PMID:27386571

  7. Parallel approach to MEMS and micro-optics interferometric testing

    NASA Astrophysics Data System (ADS)

    Kujawińska, M.; Beer, S.; Gastinger, K.; Gorecki, C.; Haugholt, K. H.; Józwik, M.; Lambelet, P.; Paris, R.; Styk, A.; Zeitner, U.

    2011-08-01

    The paper presents the novel approach to an interferometric, quantitative, massive parallel inspection of MicroElectroMechanicalSystems (MEMS), MicroOptoElectroMechanical Systems (MOEMS) and microoptics arrays. The basic idea is to adapt a micro-optical probing wafer to the M(O)EMS wafer under test. The probing wafer is exchangeable and contains one of the micro-optical interferometer arrays based on: (1) a low coherent interferometer array based on a Mirau configuration or (2) a laser interferometer array based on a Twyman-Green configuration. The optical, mechanical, and electro-optical design of the system and data analysis concept based on this approach is presented. The interferometer arrays are developed and integrated at a standard test station for micro-fabrication together with the illumination and imaging modules and special mechanics which includes scanning and electrostatic excitation systems. The smart-pixel approach is applied for massive parallel electro-optical detection and data reduction. The first results of functional tests of the system are presented. The concept is discussed in reference to the future M(O)EMS and microoptics manufacturers needs and requirements.

  8. Perspective of the Interferometric MATISSE Instrument at the VLTI

    NASA Astrophysics Data System (ADS)

    Lopez, B.

    2012-12-01

    MATISSE is a mid-infrared interferometric instrument that will operate at the VLTI in 2016 as one of the second generation instruments. One of the science case is to contribute to a better understanding of the conditions under which the planets form and evolve. Our approach consists in investigating through observation, theory and modeling the physics of proto-planetary disks by taking advantage of this new scheduled observing tool : MATISSE, that we are developing and have optimized for this scientific objective. Despite the recent advances in the observations of protoplanetary disks and in their interpretation, open questions remain in relation with the physical initial conditions giving birth to planets. The current infrared interferometers MIDI and AMBER are already used for such observations, and soon the improved spectral and imaging capabilities of the future MATISSE instrument will provide a new insight on the disc inner regions, revealing information and details about for instance the fine structures predicted by models in disks and in their inner regions (shape and size of the inner rim, curvature of the inner rim, truncature of the disk). I will present, the principle, the expected performances and the status of the MATISSE project and will give some illustrations of what kind of astrophysics is expected to be achieved.

  9. Ultrasensitive interferometric on-chip microscopy of transparent objects

    PubMed Central

    Terborg, Roland A.; Pello, Josselin; Mannelli, Ilaria; Torres, Juan P.; Pruneri, Valerio

    2016-01-01

    Light microscopes can detect objects through several physical processes, such as scattering, absorption, and reflection. In transparent objects, these mechanisms are often too weak, and interference effects are more suitable to observe the tiny refractive index variations that produce phase shifts. We propose an on-chip microscope design that exploits birefringence in an unconventional geometry. It makes use of two sheared and quasi-overlapped illuminating beams experiencing relative phase shifts when going through the object, and a complementary metal-oxide-semiconductor image sensor array to record the resulting interference pattern. Unlike conventional microscopes, the beams are unfocused, leading to a very large field of view (20 mm2) and detection volume (more than 0.5 cm3), at the expense of lateral resolution. The high axial sensitivity (<1 nm) achieved using a novel phase-shifting interferometric operation makes the proposed device ideal for examining transparent substrates and reading microarrays of biomarkers. This is demonstrated by detecting nanometer-thick surface modulations on glass and single and double protein layers. PMID:27386571

  10. Effects of luminance and spatial noise on interferometric contrast sensitivity

    NASA Astrophysics Data System (ADS)

    Coletta, Nancy J.; Sharma, Vineeta

    1995-10-01

    Optical properties of the eye contribute to the reduced visibility of spatial patterns at low luminance. To study the limits of spatial vision when optical factors are minimized, we measured contrast-sensitivity functions (CSF's) for 543.5-nm laser interference fringes imaged directly on the retina. Measurements were made in the fovea at four luminance levels, ranging from 0.3 to 300 photopic trolands (Td). At each luminance the fraction of coherent light in the stimulus pattern was varied to assess the masking effects of laser speckle, which is visible as spatial noise in fields of coherent light. Compared with published CSF's obtained under natural viewing conditions, interferometric CSF's were similar in height but broader, with the range of visibility being extended to higher spatial frequencies. The masking effects of speckle were greatest at the highest luminance and were negligible at the lowest luminance. For low coherent fractions, contrast sensitivity improved over the entire luminance range at a rate consistent with a square-root law; with purely coherent light, sensitivity tended to level off at approximately 30 Td because of speckle masking. The results indicate that the optical quality of the eye reduces the spatial bandwidth of vision even at luminances near the foveal threshold. The change in interference fringe visibility with luminance is consistent with noise-limited behavior, and the masking

  11. Spectroscopic and Interferometric Measurements of Nine K Giant Stars

    NASA Astrophysics Data System (ADS)

    Baines, Ellyn K.; Döllinger, Michaela P.; Guenther, Eike W.; Hatzes, Artie P.; Hrudkovu, Marie; van Belle, Gerard T.

    2016-09-01

    We present spectroscopic and interferometric measurements for a sample of nine K giant stars. These targets are of particular interest because they are slated for stellar oscillation observations. Our improved parameters will directly translate into reduced errors in the final masses for these stars when interferometric radii and asteroseismic densities are combined. Here, we determine each star’s limb-darkened angular diameter, physical radius, luminosity, bolometric flux, effective temperature, surface gravity, metallicity, and mass. When we compare our interferometric and spectroscopic results, we find no systematic offsets in the diameters and the values generally agree within the errors. Our interferometric temperatures for seven of the nine stars are hotter than those determined from spectroscopy with an average difference of about 380 K.

  12. An Interferometric Search for Bright Companions to 51 Pegasi

    NASA Technical Reports Server (NTRS)

    Boden, A. F.; van Belle, G. T.; Colavita, M. M.; Dumont, P. J.; Gubler, J.; Koresko, C. D.; Kulkarni, S. R.; Lane, B. F.; Mobley, D. W.; Shao, M.; Wallace, J. K.

    1998-01-01

    We report on a near-infrared, long-baseline interferometric search for luminous companions to the star 51 Pegasi conducted with the Palomar Testbed Interferometer. Our data is completely consistent with a single-star hypothesis.

  13. Intrinsic fluorescence of selenium nanoparticles for cellular imaging applications.

    PubMed

    Khalid, A; Tran, Phong A; Norello, Romina; Simpson, David A; O'Connor, Andrea J; Tomljenovic-Hanic, Snjezana

    2016-02-14

    Nanoparticles hold great potential in contributing to high-resolution bioimaging as well as for biomedical applications. Although, selenium (Se) nanoparticles (NPs) have been investigated owing to their potential roles in therapeutics, the imaging capability of these NPs has never been explored. This manuscript identifies the intrinsic fluorescence of Se NPs, which is highly beneficial for nanoscale imaging of biological structures. The emission of individual NPs and its evolution with time is explored. The photoluminescence spectra has revealed visible to near infrared emission for Se NPs. The work finally reflects on the role of this intrinsic fluorescence for in vitro imaging and tracking in fibroblast cells, without the need of any additional tags. This technique would overcome the limitations of the conventionally used methods of imaging with tagged fluorescent proteins and dyes, preventing possible adverse cellular effects or phototoxicity caused by the added fluorescent moieties. PMID:26792107

  14. A high resolution capacitive imaging sensor for manufacturing applications

    SciTech Connect

    Novak, J.L.; Wiczer, J.J.

    1990-09-06

    A high resolution capacitive image sensing technique for measuring edge and surface profiles during manufacturing processes has been invented. A prototype device utilizing this technique consists of two 0.020 in. (500 {mu}m) diameter electrodes fabricated on a printed circuit board with a 0.010 in. (250 {mu}m) gap between them. As the device is mechanically scanned over the workpiece, the spatial variations in the edge or surface to be measured interfere with an electric field imposed between the electrodes, altering the mutual capacitance. The sensor functions as a near field proximity sensor producing range images of surface imperfections. This sensor has been used in applications requiring a preview image of burrs on the edge of a machined part and other processes requiring an inspection image after automated deburring operations. 10 refs., 8 figs.

  15. Clinical applications of magnetic resonance imaging - current status

    SciTech Connect

    Cammoun, D.; Hendee, W.R.; Davis, K.A.

    1985-12-01

    Magnetic resonance imaging has far-reaching real and possible clinical applications. Its usefulness has been best explored and realized in the central nervous system, especially the posterior fossa and brain stem, where most abnormalities are better identified than with computed tomography. Its lack of ionizing radiation and extreme sensitivity to normal and abnormal patterns of myelination make magnetic resonance imaging advantageous for diagnosing many neonatal and pediatric abnormalities. New, reliable cardiac gating techniques open the way for promising studies of cardiac anatomy and function. The ability to image directly in three orthogonal planes gives us new insight into staging and follow-up of pelvic tumors and other pelvic abnormalities. Exquisite soft tissue contrast, far above that attainable by other imaging modalities, has made possible the early diagnosis of traumatic ligamentous knee injury, avascular necrosis of the hip and diagnosis, treatment planning and follow-up of musculoskeletal neoplasms. 59 references, 9 figures.

  16. Applications of terahertz (THz) technology to medical imaging

    NASA Astrophysics Data System (ADS)

    Arnone, Donald D.; Ciesla, Craig M.; Corchia, Alessandra; Egusa, S.; Pepper, Michael; Chamberlain, J. Martyn; Bezant, C.; Linfield, Edmund H.; Clothier, R.; Khammo, N.

    1999-09-01

    An imaging system has been developed based on pulses of Terahertz (THz) radiation generated and detected using all- optical effects accessed by irradiating semiconductors with ultrafast pulses of visible laser light. This technique, commonly referred to as T-Ray Imaging or THz Pulse Imaging (TPI), holds enormous promise for certain aspects of medical imaging. We have conducted an initial survey of possible medical applications of TPI and demonstrated that TPI images show good contrast between different animal tissue types. Moreover, the diagnostic power of TPI has been elicidated by the spectra available at each pixel in the image, which are markedly different for the different tissue types. This suggests that the spectral information inherent in TPI might be used to identify the type of soft and hard tissue at each pixel in an image and provide other diagnostic information not afforded by conventional imagin techniques. Preliminary TPI studies of pork skin show that 3D tomographic imaging of the skin surface and thickness is possible, and data from experiments on models of the human dermis are presented which demonstrate that different constituents of skin have different refractive indices. Lastly, we present the first THz image of human tissue, namely an extracted tooth. The time of flight of THz pulses through the tooth allows the thickness of the enamel to be determined, and is used to create an image showing the enamel and dentine regions. Absorption of THz pulses in the tooth allows the pulp cavity region to be identified. Initial evidence strongly suggests that TPI my be used to provide valuable diagnostic information pertaining to the enamel, dentine, and the pump cavity.

  17. Image Segmentation Analysis for NASA Earth Science Applications

    NASA Technical Reports Server (NTRS)

    Tilton, James C.

    2010-01-01

    NASA collects large volumes of imagery data from satellite-based Earth remote sensing sensors. Nearly all of the computerized image analysis of this data is performed pixel-by-pixel, in which an algorithm is applied directly to individual image pixels. While this analysis approach is satisfactory in many cases, it is usually not fully effective in extracting the full information content from the high spatial resolution image data that s now becoming increasingly available from these sensors. The field of object-based image analysis (OBIA) has arisen in recent years to address the need to move beyond pixel-based analysis. The Recursive Hierarchical Segmentation (RHSEG) software developed by the author is being used to facilitate moving from pixel-based image analysis to OBIA. The key unique aspect of RHSEG is that it tightly intertwines region growing segmentation, which produces spatially connected region objects, with region object classification, which groups sets of region objects together into region classes. No other practical, operational image segmentation approach has this tight integration of region growing object finding with region classification This integration is made possible by the recursive, divide-and-conquer implementation utilized by RHSEG, in which the input image data is recursively subdivided until the image data sections are small enough to successfully mitigat the combinatorial explosion caused by the need to compute the dissimilarity between each pair of image pixels. RHSEG's tight integration of region growing object finding and region classification is what enables the high spatial fidelity of the image segmentations produced by RHSEG. This presentation will provide an overview of the RHSEG algorithm and describe how it is currently being used to support OBIA or Earth Science applications such as snow/ice mapping and finding archaeological sites from remotely sensed data.

  18. Sculpting the disk around T Chamaeleontis: an interferometric view

    NASA Astrophysics Data System (ADS)

    Olofsson, J.; Benisty, M.; Le Bouquin, J.-B.; Berger, J.-P.; Lacour, S.; Ménard, F.; Henning, Th.; Crida, A.; Burtscher, L.; Meeus, G.; Ratzka, T.; Pinte, C.; Augereau, J.-C.; Malbet, F.; Lazareff, B.; Traub, W.

    2013-04-01

    Context. Circumstellar disks are believed to be the birthplace of planets and are expected to dissipate on a timescale of a few Myr. The processes responsible for the removal of the dust and gas will strongly modify the radial distribution of the circumstellar matter and consequently the spectral energy distribution. In particular, a young planet will open a gap, resulting in an inner disk dominating the near-IR emission and an outer disk emitting mostly in the far-infrared. Aims: We analyze a full set of data involving new near-infrared data obtained with the 4-telescope combiner (VLTI/PIONIER), new mid-infrared interferometric VLTI/MIDI data, literature photometric and archival data from VLT/NaCo/SAM to constrain the structure of the transition disk around T Cha. Methods: After a preliminary analysis with a simple geometric model, we used the MCFOST radiative transfer code to simultaneously model the SED and the interferometric observables from raytraced images in the H-, L'-, and N-bands. Results: We find that the dust responsible for the strong emission in excess in the near-IR must have a narrow temperature distribution with a maximum close to the silicate sublimation temperature. This translates into a narrow inner dusty disk (0.07-0.11 AU), with a significant height (H/r ~ 0.2) to increase the geometric surface illuminated by the central star. We find that the outer disk starts at about 12 AU and is partially resolved by the PIONIER, SAM, and MIDI instruments. We discuss the possibility of a self-shadowed inner disk, which can extend to distances of several AU. Finally, we show that the SAM closure phases, interpreted as the signature of a candidate companion, may actually trace the asymmetry generated by forward scattering by dust grains in the upper layers of the outer disk. These observations help constrain the inclination and position angle of the disk to about + 58° and - 70°, respectively. Conclusions: The circumstellar environment of T Cha appears

  19. Intrinsic fluorescence of selenium nanoparticles for cellular imaging applications

    NASA Astrophysics Data System (ADS)

    Khalid, A.; Tran, Phong A.; Norello, Romina; Simpson, David A.; O'Connor, Andrea J.; Tomljenovic-Hanic, Snjezana

    2016-02-01

    Nanoparticles hold great potential in contributing to high-resolution bioimaging as well as for biomedical applications. Although, selenium (Se) nanoparticles (NPs) have been investigated owing to their potential roles in therapeutics, the imaging capability of these NPs has never been explored. This manuscript identifies the intrinsic fluorescence of Se NPs, which is highly beneficial for nanoscale imaging of biological structures. The emission of individual NPs and its evolution with time is explored. The photoluminescence spectra has revealed visible to near infrared emission for Se NPs. The work finally reflects on the role of this intrinsic fluorescence for in vitro imaging and tracking in fibroblast cells, without the need of any additional tags. This technique would overcome the limitations of the conventionally used methods of imaging with tagged fluorescent proteins and dyes, preventing possible adverse cellular effects or phototoxicity caused by the added fluorescent moieties.Nanoparticles hold great potential in contributing to high-resolution bioimaging as well as for biomedical applications. Although, selenium (Se) nanoparticles (NPs) have been investigated owing to their potential roles in therapeutics, the imaging capability of these NPs has never been explored. This manuscript identifies the intrinsic fluorescence of Se NPs, which is highly beneficial for nanoscale imaging of biological structures. The emission of individual NPs and its evolution with time is explored. The photoluminescence spectra has revealed visible to near infrared emission for Se NPs. The work finally reflects on the role of this intrinsic fluorescence for in vitro imaging and tracking in fibroblast cells, without the need of any additional tags. This technique would overcome the limitations of the conventionally used methods of imaging with tagged fluorescent proteins and dyes, preventing possible adverse cellular effects or phototoxicity caused by the added fluorescent

  20. Imaging mass spectrometry with nuclear microprobes for biological applications

    NASA Astrophysics Data System (ADS)

    Nakata, Y.; Yamada, H.; Honda, Y.; Ninomiya, S.; Seki, T.; Aoki, T.; Matsuo, J.

    2009-06-01

    A mass spectrometric technique using nuclear microprobes is presented in this paper for biological applications. In recent years, imaging mass spectrometry has become an increasingly important technique for visualizing the spatial distribution of molecular species in biological tissues and cells. However, due to low yields of large molecular ions, the conventional secondary ion mass spectrometry (SIMS), that uses keV primary ion beams, is typically applied for imaging of either elements or low mass compounds. In this study, we performed imaging mass spectrometry using MeV ion beams collimated to about 10 μm, and successfully obtained molecular ion images from plant and animal cell sections. The molecular ion imaging of the pollen section showed high intensities of PO3- ions in the pollen cytoplasm, compared to the pollen wall, and indicated the heterogeneous distribution in the cytoplasm. The 3T3-L1 cell image revealed the high intensity of PO3- ions, in particular from the cell nucleus. The result showed that not only the individual cell, but also the cell nucleus could be identified with the present imaging technique.

  1. Novel Applications of Laser Doppler Vibration Measurements to Medical Imaging

    NASA Astrophysics Data System (ADS)

    Tabatabai, Habib; Oliver, David E.; Rohrbaugh, John W.; Papadopoulos, Christopher

    2013-06-01

    Laser Doppler Vibrometry (LDV) has been widely used in engineering applications involving non-contact vibration and sound measurements. This technique has also been used in some biomedical applications including hearing research. The detectable frequencies are in the range of near-DC to 1 GHz or higher. This paper reviews applications of LDV in biomedical engineering and proposes new medical imaging applications based on measuring surface vibrations of tissues and organs. Tests were conducted on human skin using single point and scanning laser vibrometers. These tests suggest that skin vibrations due to the forcing excitation from the heart can be used in imaging of blood flow. The results of these tests illustrate the potential of such vibration measurements in a variety of diagnostic medical imaging applications including blood flow/restrictions, real-time monitoring of blood pressure variations, wound healing, muscle movements, etc. The fact that the measurements can be conducted remotely (non-contact) is an important benefit that adds to the promise of this approach.

  2. Interpretation of Medical Imaging Data with a Mobile Application: A Mobile Digital Imaging Processing Environment

    PubMed Central

    Lin, Meng Kuan; Nicolini, Oliver; Waxenegger, Harald; Galloway, Graham J.; Ullmann, Jeremy F. P.; Janke, Andrew L.

    2013-01-01

    Digital Imaging Processing (DIP) requires data extraction and output from a visualization tool to be consistent. Data handling and transmission between the server and a user is a systematic process in service interpretation. The use of integrated medical services for management and viewing of imaging data in combination with a mobile visualization tool can be greatly facilitated by data analysis and interpretation. This paper presents an integrated mobile application and DIP service, called M-DIP. The objective of the system is to (1) automate the direct data tiling, conversion, pre-tiling of brain images from Medical Imaging NetCDF (MINC), Neuroimaging Informatics Technology Initiative (NIFTI) to RAW formats; (2) speed up querying of imaging measurement; and (3) display high-level of images with three dimensions in real world coordinates. In addition, M-DIP provides the ability to work on a mobile or tablet device without any software installation using web-based protocols. M-DIP implements three levels of architecture with a relational middle-layer database, a stand-alone DIP server, and a mobile application logic middle level realizing user interpretation for direct querying and communication. This imaging software has the ability to display biological imaging data at multiple zoom levels and to increase its quality to meet users’ expectations. Interpretation of bioimaging data is facilitated by an interface analogous to online mapping services using real world coordinate browsing. This allows mobile devices to display multiple datasets simultaneously from a remote site. M-DIP can be used as a measurement repository that can be accessed by any network environment, such as a portable mobile or tablet device. In addition, this system and combination with mobile applications are establishing a virtualization tool in the neuroinformatics field to speed interpretation services. PMID:23847587

  3. Image quality criteria for wide-field x-ray imaging applications

    NASA Astrophysics Data System (ADS)

    Thompson, Patrick L.; Harvey, James E.

    1999-10-01

    For staring, wide-field applications, such as a solar x-ray imager, the severe off-axis aberrations of the classical Wolter Type-I grazing incidence x-ray telescope design drastically limits the 'resolution' near the solar limb. A specification upon on-axis fractional encircled energy is thus not an appropriate image quality criterion for such wide-angle applications. A more meaningful image quality criterion would be a field-weighted-average measure of 'resolution.' Since surface scattering effects from residual optical fabrication errors are always substantial at these very short wavelengths, the field-weighted-average half- power radius is a far more appropriate measure of aerial resolution. If an ideal mosaic detector array is being used in the focal plane, the finite pixel size provides a practical limit to this system performance. Thus, the total number of aerial resolution elements enclosed by the operational field-of-view, expressed as a percentage of the n umber of ideal detector pixels, is a further improved image quality criterion. In this paper we describe the development of an image quality criterion for wide-field applications of grazing incidence x-ray telescopes which leads to a new class of grazing incidence designs described in a following companion paper.

  4. Onboard Interferometric SAR Processor for the Ka-Band Radar Interferometer (KaRIn)

    NASA Technical Reports Server (NTRS)

    Esteban-Fernandez, Daniel; Rodriquez, Ernesto; Peral, Eva; Clark, Duane I.; Wu, Xiaoqing

    2011-01-01

    An interferometric synthetic aperture radar (SAR) onboard processor concept and algorithm has been developed for the Ka-band radar interferometer (KaRIn) instrument on the Surface and Ocean Topography (SWOT) mission. This is a mission- critical subsystem that will perform interferometric SAR processing and multi-look averaging over the oceans to decrease the data rate by three orders of magnitude, and therefore enable the downlink of the radar data to the ground. The onboard processor performs demodulation, range compression, coregistration, and re-sampling, and forms nine azimuth squinted beams. For each of them, an interferogram is generated, including common-band spectral filtering to improve correlation, followed by averaging to the final 1 1-km ground resolution pixel. The onboard processor has been prototyped on a custom FPGA-based cPCI board, which will be part of the radar s digital subsystem. The level of complexity of this technology, dictated by the implementation of interferometric SAR processing at high resolution, the extremely tight level of accuracy required, and its implementation on FPGAs are unprecedented at the time of this reporting for an onboard processor for flight applications.

  5. Imaging retinal ganglion cells: enabling experimental technology for clinical application.

    PubMed

    Smith, Corey A; Chauhan, Balwantray C

    2015-01-01

    Recent advances in clinical ophthalmic imaging have enhanced patient care. However, the ability to differentiate retinal neurons, such as retinal ganglion cells (RGCs), would advance many areas within ophthalmology, including the screening and monitoring of glaucoma and other optic neuropathies. Imaging at the single cell level would take diagnostics to the next level. Experimental methods have provided techniques and insight into imaging RGCs, however no method has yet to be translated to clinical application. This review provides an overview of the importance of non-invasive imaging of RGCs and the clinically relevant capabilities. In addition, we report on experimental data from wild-type mice that received an in vivo intravitreal injection of a neuronal tracer that labelled RGCs, which in turn were monitored for up to 100 days post-injection with confocal scanning laser ophthalmoscopy. We were able to demonstrate efficient and consistent RGC labelling with this delivery method and discuss the issue of cell specificity. This type of experimental work is important in progressing towards clinically applicable methods for monitoring loss of RGCs in glaucoma and other optic neuropathies. We discuss the challenges to translating these findings to clinical application and how this method of tracking RGCs in vivo could provide valuable structural and functional information to clinicians. PMID:25448921

  6. Response of interferometric gravitational wave detectors

    SciTech Connect

    Finn, Lee Samuel

    2009-01-15

    The derivation of the response function of an interferometric gravitational wave detector is a paradigmatic calculation in the field of gravitational wave detection. Surprisingly, the standard derivation of the response wave detectors makes several unjustifiable assumptions, both conceptual and quantitative, regarding the coordinate trajectory and coordinate velocity of the null geodesic the light travels along. These errors, which appear to have remained unrecognized for at least 35 years, render the standard derivation inadequate and misleading as an archetype calculation. Here we identify the flaws in the existing derivation and provide, in full detail, a correct derivation of the response of a single-bounce Michelson interferometer to gravitational waves, following a procedure that will always yield correct results; compare it to the standard, but incorrect, derivation; show where the earlier mistakes were made; and identify the general conditions under which the standard derivation will yield correct results. By a fortuitous set of circumstances, not generally so, the final result is the same in the case of Minkowski background spacetime, synchronous coordinates, transverse-traceless gauge metric perturbations, and arm mirrors at coordinate rest.

  7. ISAS: interferometric stratospheric astrometry for solar system

    NASA Astrophysics Data System (ADS)

    Gai, M.; Fienga, A.; Lattanzi, M. G.; Riva, A.; Vecchiato, A.; Gallieni, D.; Chaillot, S.; Ligori, S.; Loreggia, D.

    2012-09-01

    The Interferometric Stratospheric Astrometry for Solar system (ISAS) project is designed for high precision astrometry on the brightest planets of the Solar System, with reference to many field stars, at the milli-arcsec (mas) level or better. The science goal is the improvement on our knowledge of the dynamics of the Solar System, complementing the Gaia observations of fainter objects. The technical goal is the validation of basic concepts for the proposed Gamma Astrometric Measurement Experiment (GAME) space mission, in particular, combination of Fizeau interferometry and coronagraphic techniques by means of pierced mirrors, intermediate angle dual field astrometry, smart focal plane management for increased dynamic range and pointing correction. We discuss the suitability of the stratospheric environment, close to space conditions, to the astrometric requirements. The instrument concept is a multiple field, multiple aperture Fizeau interferometer, observing simultaneously four fields, in order to improve on the available number of reference stars. Coronagraphic solutions are introduced to allow observation of internal planets (Mercury and Venus), as well as of external planets over a large fraction of their orbit, i.e. also close to conjunction with the Sun. We describe the science motivation, the proposed experiment profile and the expected performance.

  8. Interferometric Studies of Low-Mass Protostars

    NASA Astrophysics Data System (ADS)

    Jørgensen, Jes K.

    2011-12-01

    With the advances in high angular resolution (sub)millimeter observations of low-mass protostars, windows of opportunities are opening up for very detailed studies of the molecular structure of star forming regions on wide range of spatial scales. Deeply embedded protostars provide an important laboratory to study the chemistry of star formation - providing the link between dense regions in molecular clouds from which stars are formed, i.e., the initial conditions and the end product in terms of, e.g., disk and planet formation. High angular resolution observations at (sub)millimeter wavelengths provide an important tool for studying the chemical composition of such low-mass protostars. They for example constrain the spatial molecular abundance variations - and can thereby identify which species are useful tracers of different components of the protostars at different evolutionary stages. In this review I discuss the possibilities and limitations of using high angular resolution (sub)millimeter interferometric observations for studying the chemical evolution of low-mass protostars - with a particular keen eye toward near-future ALMA observations.

  9. Acoustic vs Interferometric Measurements of Lightning

    NASA Astrophysics Data System (ADS)

    Arechiga, R. O.; Erives, H.; Sonnenfeld, R. G.; Stanley, M. A.; Rison, W.; Thomas, R. J.; Edens, H. E.; Lapierre, J. L.; Stock, M.; Jensen, D.; Morris, K.

    2015-12-01

    During the summer of 2015 we acquired acoustic and RF data on severalflashes from thunderstorms over Fort Morgan CO. and Langmuir Laboratoryin the Magdalena mountains of central New Mexico. The acoustic arrayswere located at a distance of roughly 150 m from the interferometers.Lightning mapping array and slow antenna data were also obtained. Theacoustic arrays consist of arrays of five audio-range and six infrasoundmicrophones operating at 50 KHz and 1 KHz respectively. The lightninginterferometer at Fort Morgan CO. consists of three flat-plate, 13" diameterantennas at the vertices of an equilateral 50 m per side triangle. Theinterferometer at Langmuir Laboratory consists of three 13" dishes separatedby about 15 m. Both interferometers, operating at 180 Megasamples persecond, use the analysis software and digitizer hardware pioneered byStanley, Stock et al. The high data rate allows for excellent spatialresolution of high speed (and typically high current) processes such asK-changes, return strokes and dart-leaders. In previous studies, we haveshown the usefulness of acoustic recordings to locate thunder sources aswell as infrasound pulses from lightning. This work will present acomparison of Acoustic and Interferometric measurements from lightning,using some interesting flashes, including a positive cloud to ground,that occurred in these campaigns.

  10. Neutron Interferometric Search for Chameleon Dark Energy

    NASA Astrophysics Data System (ADS)

    Heacock, Benjamin; Index Collaboration

    2015-10-01

    The chameleon model for dark energy proposed by Khoury and Weltman is one of the only theories of dark energy which can be tested using laboratory experiments. The theory consists of a nonlinear scalar field whose range and intensity is a sensitive function of the local matter density, with the field becoming nonzero over ranges greater than 100 microns in only low density regions of space. We are searching for the induced phase shift due to a coupling of the chameleon to matter using neutron interferometry. By placing a two-chamber gas cell inside the neutron interferometer, we measure the neutron phase difference between low pressure (0.00025 torr) and higher pressure (0.1 torr) helium gas. The chameleon field is predicted to be suppressed only at the higher pressure, resulting in a phase from the chameleon on the low pressure side of the chamber. A double-difference technique is used to subtract the phase shift from the gas and chamber walls. We will discuss this experiment, ran at the NIST Center for Neutron Research, and present current constraints on the chameleon field. Interferometric Dark Energy eXperiment

  11. Photoactivatable fluorophores and techniques for biological imaging applications

    PubMed Central

    Zheng, Genhua

    2013-01-01

    Photoactivatable fluorophores (PAFs) are powerful imaging probes for tracking molecular and cellular dynamics with high spatiotemporal resolution in biological systems. Recent developments in biological microscopy have raised new demands for engineering new PAFs with improved properties such as high two photon excitation efficiency, reversibility, cellular delivery and targeting. Here we review the history and some of the recent developments in this area, emphasizing our efforts in developing a new class of caged coumarins and related imaging methods for studying dynamic cell-cell communication through gap junction channels, and in extending the application of these caged coumarins to new areas including spatiotemporal control of microRNA activity in vivo. PMID:22252510

  12. The application of image processing to satellite navigation. [considering landmarks

    NASA Technical Reports Server (NTRS)

    Hord, R. M.

    1975-01-01

    Given the locations of several landmarks on a satellite acquired image and their true geographic coordinates, the position and orientation of the satellite can be determined. Two methods for automatically locating the image coordinates of specified landmarks are described. The first, a particularly fast sequential similarity detection algorithm for template matching was originally described by Nagel and Rosenfeld. The second method involves iteratively resampling the picture function in the vicinity of the anticipated landmark. A variety of other speedup methods is also described. An application to SMS imagery is envisioned.

  13. Scope and applications of translation invariant wavelets to image registration

    NASA Technical Reports Server (NTRS)

    Chettri, Samir; LeMoigne, Jacqueline; Campbell, William

    1997-01-01

    The first part of this article introduces the notion of translation invariance in wavelets and discusses several wavelets that have this property. The second part discusses the possible applications of such wavelets to image registration. In the case of registration of affinely transformed images, we would conclude that the notion of translation invariance is not really necessary. What is needed is affine invariance and one way to do this is via the method of moment invariants. Wavelets or, in general, pyramid processing can then be combined with the method of moment invariants to reduce the computational load.

  14. Colour perfusion imaging: a new application of computed tomography.

    PubMed

    Miles, K A; Hayball, M; Dixon, A K

    1991-03-16

    We describe a new application for imaging with computed tomography (CT) in which a quantifiable map of tissue perfusion is created and displayed by means of a colour scale. A rapid sequence of images is acquired without table movement immediately after a bolus intravenous injection of radiographic contrast medium. The rate of enhancement in each pixel within the chosen slice can then be used to determine perfusion. The technique provides a quantifiable display of regional perfusion combined with the high spatial resolution afforded by CT.

  15. Application of digital image processing techniques to astronomical imagery, 1979

    NASA Technical Reports Server (NTRS)

    Lorre, J. J.

    1979-01-01

    Several areas of applications of image processing to astronomy were identified and discussed. These areas include: (1) deconvolution for atmospheric seeing compensation; a comparison between maximum entropy and conventional Wiener algorithms; (2) polarization in galaxies from photographic plates; (3) time changes in M87 and methods of displaying these changes; (4) comparing emission line images in planetary nebulae; and (5) log intensity, hue saturation intensity, and principal component color enhancements of M82. Examples are presented of these techniques applied to a variety of objects.

  16. Development of CCD imaging sensors for space applications, phase 1

    NASA Technical Reports Server (NTRS)

    Antcliffe, G. A.

    1975-01-01

    The results of an experimental investigation to develop a large area charge coupled device (CCD) imager for space photography applications are described. Details of the design and processing required to achieve 400 X 400 imagers are presented together with a discussion of the optical characterization techniques developed for this program. A discussion of several aspects of large CCD performance is given with detailed test reports. The areas covered include dark current, uniformity of optical response, square wave amplitude response, spectral responsivity and dynamic range.

  17. Real-time multispectral imaging application for poultry safety inspection

    NASA Astrophysics Data System (ADS)

    Park, Bosoon; Lawrence, Kurt C.; Windham, William R.; Snead, Matthew P.

    2006-02-01

    The ARS imaging research group in Athens, Georgia has developed a real-time multispectral imaging system for fecal and ingesta contaminant detection on broiler carcasses for poultry industry. The industrial scale system includes a common aperture camera with three visible wavelength optical trim filters. This paper demonstrates calibration of common aperture multispectral imaging hardware and real-time image processing software. The software design, especially the Unified Modeling Language (UML) design approach was used to develop real-time image processing software for on-line application. The UML models including class, object, activity, sequence, and collaboration diagram were presented. Both hardware and software for a real-time fecal and ingesta contaminant detection were tested at the pilot-scale poultry processing line. The test results of industrial sacle real-time system showed that the multispectral imaging technique performed well for detecting fecal contaminants with a commercial processing speed (currently 140 birds per minute). The accuracy for the detection of fecal and ingesta contaminates was approximately 96%.

  18. Review of biomedical Čerenkov luminescence imaging applications

    PubMed Central

    Tanha, Kaveh; Pashazadeh, Ali Mahmoud; Pogue, Brian W

    2015-01-01

    Čerenkov radiation is a fascinating optical signal, which has been exploited for unique diagnostic biological sensing and imaging, with significantly expanded use just in the last half decade. Čerenkov Luminescence Imaging (CLI) has desirable capabilities for niche applications, using specially designed measurement systems that report on radiation distributions, radiotracer and nanoparticle concentrations, and are directly applied to procedures such as medicine assessment, endoscopy, surgery, quality assurance and dosimetry. When compared to the other imaging tools such as PET and SPECT, CLI can have the key advantage of lower cost, higher throughput and lower imaging time. CLI can also provide imaging and dosimetry information from both radioisotopes and linear accelerator irradiation. The relatively short range of optical photon transport in tissue means that direct Čerenkov luminescence imaging is restricted to small animals or near surface human use. Use of Čerenkov-excitation for additional molecular probes, is now emerging as a key tool for biosensing or radiosensitization. This review evaluates these new improvements in CLI for both medical value and biological insight. PMID:26309766

  19. Retroreflective microprismatic materials in image-based control applications

    NASA Astrophysics Data System (ADS)

    Serikova, Mariya G.; Pantyushin, Anton V.; Gorbunova, Elena V.; Anisimov, Andrei G.

    2015-05-01

    This work addresses accurate position measurement of reference marks made of retroreective microprismatic materials by image-based systems. High reflection microprismatic technology implies tiny hermetically sealed pockets, which improve material reflectivity, but result in non-reflective preprinted netting pattern. The mark pattern to be used for measuring can be simply printed on the reflective material as an opaque area with predefined shape. However, the non-reflecting pattern acts as a spatial filter that affects resultant spatial reflectivity of the mark. When an image of the mark is taken, the desired mark shape can be deformed by the netting pattern. This deformational may prevent accurate estimation of the mark position in the image. In this paper experimental comparison of three image filtering approaches (median filtering, morphological close and filtering in a frequency domain) in order to minimize the affection of the netting pattern is provided. These filtering approaches were experimentally evaluated by processing of the images of the mark that was translated in a camera field of view. For that a developed experimental setup including a camera with LED backlight and the mark placed on a translation stage was used. The experiment showed that median filtering provided better netting pattern elimination and higher accuracy of key features position estimation (approximately +/-0.1 pix) in the condition of the experiment. The ways of future use of reference marks based on microprismatic material in image-based control applications are discussed.

  20. Localising fast radio bursts and other transients using interferometric arrays

    NASA Astrophysics Data System (ADS)

    Obrocka, M.; Stappers, B.; Wilkinson, P.

    2015-07-01

    A new population of sources emitting fast and bright transient radio bursts (FRBs) has recently been identified. Their observed high dispersion measures suggests an extragalactic origin, and accurately determining their positions and distances will provide an opportunity to study the magneto-ionic properties of the intergalactic medium. So far, FRBs have all been found using large dishes equipped with multi-pixel arrays. While these dishes are well-suited to discovering transient sources, they are poor at providing accurate localisations. A 2D snapshot image of the sky, made with a correlation interferometer array, can accurately localise many compact radio sources simultaneously. However, the required time resolution and the need to detect them in real time makes this currently impractical. In a beam-forming approach many narrow tied-array beams (TABs) are produced and the advantages of single dishes and interferometers can be combined. We present a proof-of-concept analysis of a new non-imaging method that utilises the additional spectral and comparative spatial information obtained from multiply overlapping TABs to estimate a transient source location with up to arcsecond accuracy in almost real time. We demonstrate this for a variety of interferometric configurations, that is LOFAR and MeerKAT, and show that the estimated angular position may be sufficient for identifying a host galaxy or other related object, without reference to other simultaneous or follow-up observations. In cases where the position is less accurately determined, we can still significantly reduce the area that needs to be searched for associated emission at other wavelengths and from potential host galaxies.

  1. Interferometric measurement of the angular velocity of moving humans

    NASA Astrophysics Data System (ADS)

    Nanzer, Jeffrey A.

    2012-06-01

    This paper presents an analysis of the measurement of the angular velocity of walking humans using a millimeter-wave correlation interferometer. Measurement of the angular velocity of moving objects is a desirable function in remote sensing applications. Doppler radar sensors are able to measure the signature of moving humans based on micro-Doppler analysis; however, a person moving with little to no radial velocity produces negligible Doppler returns. Measurement of the angular movement of humans can be done with traditional radar techniques, however the process involves either continuous tracking with narrow beamwidth or angle-of-arrival estimation algorithms. A new method of measuring the angular velocity of moving objects using interferometry has recently been developed which measures the angular velocity of an object without tracking or complex processing. The frequency of the interferometer signal response is proportional to the angular velocity of the object as it passes through the interferometer beam pattern. In this paper, the theory of the interferometric measurement of angular velocity is covered and simulations of the response of a walking human are presented. Simulations are produced using a model of a walking human to show the significant features associated with the interferometer response, which may be used in classification algorithms.

  2. Performance comparison of fiber tips in interferometric displacement mesurements

    SciTech Connect

    Moro, Erik; Grahn, Rick R; Karimi, Hussain H; Wilson, Kyle L; Puckett, Anthony D

    2011-01-24

    Fiber optic displacement sensors have many potential advantages over traditional displacement measurement techniques, including small size, immunity to electromagnetic interference, electrical isolation, and high resolution. In this report, we focus on an interferometric fiber optic sensor, where the gap between the fiber tip and the device under test forms a Fabry-Perot resonant cavity. An optical interrogator measures the reflected intensity at wavelengths ranging from 1510 to 1590 nm. The spacing between resonant frequencies allows us to determine the distance from the tip to the device under test. We consider ferrule connector angled physical contact (FC/APC), ferrule connector ultra physical contact (FC/UPC) and unpolished cleaved tips and compare their influence on sensor performance. A plane wave propagation model is proposed for predicting tip effects. Comparisons are made on the basis of sensor measurement range, resolution, and sensitivity to changes in test conditions. In this paper, we discuss the experimental setup, detail our analysis, and present test results with recommendations for the applications of each tip.

  3. Controlling interferometric properties of nanoporous anodic aluminium oxide

    NASA Astrophysics Data System (ADS)

    Kumeria, Tushar; Losic, Dusan

    2012-01-01

    A study of reflective interference spectroscopy [RIfS] properties of nanoporous anodic aluminium oxide [AAO] with the aim to develop a reliable substrate for label-free optical biosensing is presented. The influence of structural parameters of AAO including pore diameters, inter-pore distance, pore length, and surface modification by deposition of Au, Ag, Cr, Pt, Ni, and TiO2 on the RIfS signal (Fabry-Perot fringe) was explored. AAO with controlled pore dimensions was prepared by electrochemical anodization of aluminium using 0.3 M oxalic acid at different voltages (30 to 70 V) and anodization times (10 to 60 min). Results show the strong influence of pore structures and surface modifications on the interference signal and indicate the importance of optimisation of AAO pore structures for RIfS sensing. The pore length/pore diameter aspect ratio of AAO was identified as a suitable parameter to tune interferometric properties of AAO. Finally, the application of AAO with optimised pore structures for sensing of a surface binding reaction of alkanethiols (mercaptoundecanoic acid) on gold surface is demonstrated.

  4. Theoretical Design of a Depolarized Interferometric Fiber-Optic Gyroscope (IFOG) on SMF-28 Single-Mode Standard Optical Fiber Based on Closed-Loop Sinusoidal Phase Modulation with Serrodyne Feedback Phase Modulation Using Simulation Tools for Tactical and Industrial Grade Applications.

    PubMed

    Pérez, Ramón José; Álvarez, Ignacio; Enguita, José María

    2016-04-27

    This article presents, by means of computational simulation tools, a full analysis and design of an Interferometric Fiber-Optic Gyroscope (IFOG) prototype based on a closed-loop configuration with sinusoidal bias phase- modulation. The complete design of the different blocks, optical and electronic, is presented, including some novelties as the sinusoidal bias phase-modulation and the use of an integrator to generate the serrodyne phase-modulation signal. The paper includes detailed calculation of most parameter values, and the plots of the resulting signals obtained from simulation tools. The design is focused in the use of a standard single-mode optical fiber, allowing a cost competitive implementation compared to commercial IFOG, at the expense of reduced sensitivity. The design contains an IFOG model that accomplishes tactical and industrial grade applications (sensitivity ≤ 0.055 °/h). This design presents two important properties: (1) an optical subsystem with advanced conception: depolarization of the optical wave by means of Lyot depolarizers, which allows to use a sensing coil made by standard optical fiber, instead by polarization maintaining fiber, which supposes consequent cost savings and (2) a novel and simple electronic design that incorporates a linear analog integrator with reset in feedback chain, this integrator generating a serrodyne voltage-wave to apply to Phase-Modulator (PM), so that it will be obtained the interferometric phase cancellation. This particular feedback design with sawtooth-wave generated signal for a closed-loop configuration with sinusoidal bias phase modulation has not been reported till now in the scientific literature and supposes a considerable simplification with regard to previous designs based on similar configurations. The sensing coil consists of an 8 cm average diameter spool that contains 300 m of standard single-mode optical-fiber (SMF-28 type) realized by quadrupolar winding. The working wavelength will be

  5. Theoretical Design of a Depolarized Interferometric Fiber-Optic Gyroscope (IFOG) on SMF-28 Single-Mode Standard Optical Fiber Based on Closed-Loop Sinusoidal Phase Modulation with Serrodyne Feedback Phase Modulation Using Simulation Tools for Tactical and Industrial Grade Applications.

    PubMed

    Pérez, Ramón José; Álvarez, Ignacio; Enguita, José María

    2016-01-01

    This article presents, by means of computational simulation tools, a full analysis and design of an Interferometric Fiber-Optic Gyroscope (IFOG) prototype based on a closed-loop configuration with sinusoidal bias phase- modulation. The complete design of the different blocks, optical and electronic, is presented, including some novelties as the sinusoidal bias phase-modulation and the use of an integrator to generate the serrodyne phase-modulation signal. The paper includes detailed calculation of most parameter values, and the plots of the resulting signals obtained from simulation tools. The design is focused in the use of a standard single-mode optical fiber, allowing a cost competitive implementation compared to commercial IFOG, at the expense of reduced sensitivity. The design contains an IFOG model that accomplishes tactical and industrial grade applications (sensitivity ≤ 0.055 °/h). This design presents two important properties: (1) an optical subsystem with advanced conception: depolarization of the optical wave by means of Lyot depolarizers, which allows to use a sensing coil made by standard optical fiber, instead by polarization maintaining fiber, which supposes consequent cost savings and (2) a novel and simple electronic design that incorporates a linear analog integrator with reset in feedback chain, this integrator generating a serrodyne voltage-wave to apply to Phase-Modulator (PM), so that it will be obtained the interferometric phase cancellation. This particular feedback design with sawtooth-wave generated signal for a closed-loop configuration with sinusoidal bias phase modulation has not been reported till now in the scientific literature and supposes a considerable simplification with regard to previous designs based on similar configurations. The sensing coil consists of an 8 cm average diameter spool that contains 300 m of standard single-mode optical-fiber (SMF-28 type) realized by quadrupolar winding. The working wavelength will be

  6. Theoretical Design of a Depolarized Interferometric Fiber-Optic Gyroscope (IFOG) on SMF-28 Single-Mode Standard Optical Fiber Based on Closed-Loop Sinusoidal Phase Modulation with Serrodyne Feedback Phase Modulation Using Simulation Tools for Tactical and Industrial Grade Applications

    PubMed Central

    Pérez, Ramón José; Álvarez, Ignacio; Enguita, José María

    2016-01-01

    This article presents, by means of computational simulation tools, a full analysis and design of an Interferometric Fiber-Optic Gyroscope (IFOG) prototype based on a closed-loop configuration with sinusoidal bias phase- modulation. The complete design of the different blocks, optical and electronic, is presented, including some novelties as the sinusoidal bias phase-modulation and the use of an integrator to generate the serrodyne phase-modulation signal. The paper includes detailed calculation of most parameter values, and the plots of the resulting signals obtained from simulation tools. The design is focused in the use of a standard single-mode optical fiber, allowing a cost competitive implementation compared to commercial IFOG, at the expense of reduced sensitivity. The design contains an IFOG model that accomplishes tactical and industrial grade applications (sensitivity ≤ 0.055 °/h). This design presents two important properties: (1) an optical subsystem with advanced conception: depolarization of the optical wave by means of Lyot depolarizers, which allows to use a sensing coil made by standard optical fiber, instead by polarization maintaining fiber, which supposes consequent cost savings and (2) a novel and simple electronic design that incorporates a linear analog integrator with reset in feedback chain, this integrator generating a serrodyne voltage-wave to apply to Phase-Modulator (PM), so that it will be obtained the interferometric phase cancellation. This particular feedback design with sawtooth-wave generated signal for a closed-loop configuration with sinusoidal bias phase modulation has not been reported till now in the scientific literature and supposes a considerable simplification with regard to previous designs based on similar configurations. The sensing coil consists of an 8 cm average diameter spool that contains 300 m of standard single-mode optical-fiber (SMF-28 type) realized by quadrupolar winding. The working wavelength will be

  7. Tethered Formation Configurations: Meeting the Scientific Objectives of Large Aperture and Interferometric Science

    NASA Technical Reports Server (NTRS)

    Farley, Rodger E.; Quinn, David A.; Brodeur, Stephen J. (Technical Monitor)

    2001-01-01

    With the success of the Hubble Space Telescope, it has become apparent that new frontiers of science and discovery are made every time an improvement in imaging resolution is made. For the HST working primarily in the visible and near-visible spectrum, this meant designing, building, and launching a primary mirror approximately three meters in diameter. Conventional thinking tells us that accomplishing a comparable improvement in resolution at longer wavelengths for Earth and Space Science applications requires a corresponding increase in the size of the primary mirror. For wavelengths in the sub-millimeter range, a very large telescope with an effective aperture in excess of one kilometer in diameter would be needed to obtain high quality angular resolution. Realistically a single aperture this large is practically impossible. Fortunately such large apertures can be constructed synthetically. Possibly as few as three 34 meter diameter mirrors flying in precision formation could be used to collect light at these longer wavelengths permitting not only very large virtual aperture science to be carried out, but high-resolution interferometry as well. To ensure the longest possible mission duration, a system of tethered spacecraft will be needed to mitigate the need for a great deal of propellant. A spin-stabilized, tethered formation will likely meet these requirements. Several configurations have been proposed which possibly meet the needs of the Space Science community. This paper discusses two of them, weighing the relative pros and cons of each concept. The ultimate goal being to settle on a configuration which combines the best features of structure, tethers, and formation flying to meet the ambitious requirements necessary to make future large synthetic aperture and interferometric science missions successful.

  8. Tethered Formation Configurations: Meeting the Scientific Objectives of Large Aperture and Interferometric Science

    NASA Technical Reports Server (NTRS)

    Farley, Rodger E.; Quinn, David A.

    2004-01-01

    With the success of the Hubble Space Telescope, it has become apparent that new frontiers of science and discovery are made every time an improvement in imaging resolution is made. For the HST working primarily in the visible and near-visible spectrum, this meant designing, building and launching a primary mirror approximately three meters in diameter. Conventional thinking tells us that accomplishing a comparable improvement in resolution at longer wavelengths for Earth and Space Science applications requires a corresponding increase in the size of the primary mirror. For wavelengths in the sub-millimeter range, a very large telescope with an effective aperture in excess of one kilometer in diameter would be needed to obtain high quality angular resolution. Realistically a single aperture this large is practically impossible. Fortunately such large apertures can be constructed synthetically. Possibly as few as three 3 - 4 meter diameter mirrors flying in precision formation could be used to collect light at these longer wavelengths permitting not only very large virtual aperture science to be carried out, but high-resolution interferometry as well. To ensure the longest possible mission duration, a system of tethered spacecraft will be needed to mitigate the need for a great deal of propellant. A spin-stabilized, tethered formation will likely meet these requirements. Several configurations have been proposed which possibly meet the needs of the Space Science community. This paper discusses two of them, weighing the relative pros and cons of each concept. The ultimate goal being to settle on a configuration which combines the best features of structure, tethers and formation flying to meet the ambitious requirements necessary to make future large synthetic aperture and interferometric science missions successful.

  9. Millimeter-wave interferometric radiometry for the detection and geolocation of low-power signals

    NASA Astrophysics Data System (ADS)

    Dowgiallo, David J.; Twarog, Elizabeth M.; Rauen, Steve; Peters, Wendy M.; Lazio, T. Joseph; McGlothlin, Norman R.; Helmboldt, Joseph F.; Gaiser, Peter W.

    2011-05-01

    Millimeter wave detection and imaging is becoming increasingly important with the proliferation of hostile, mobile millimeter wave threats from both weapons systems and communication links. Improved force protection, surveillance, and targeting will rely increasingly on the interception, detection, geo-sorting, and the identification of sources, such as point-to point communication systems, missile seekers, precision guided munitions, and fire control radar systems. This paper describes the Naval Research Laboratory's (NRL) demonstration broadband passive millimeter wave (mmW) interferometric imaging system. This Ka-band system will provide a capability for meter-precision geolocation for imaged objects. The interferometer uses a distributed array of 12 antenna elements to synthesize a large aperture. Each antenna is packaged into an individual receiver, from which a baseband signal is recorded. The correlator is software-based, utilizing signal processing techniques for visibilities, and image formation via beamforming methods. This paper presents first results from an interferometer flight campaign.

  10. Interferometric Processing of SLC Sentinel-1 TOPS Data

    NASA Astrophysics Data System (ADS)

    Grandin, Raphael

    2015-05-01

    InSAR processing usually involves two successive steps: focusing and interferometry. Most public-domain InSAR processing toolboxes are capable of performing both operations with data acquired in the standard Stripmap mode, starting from raw SAR data (level 0). However, the focusing of burst-mode data, such as TOPS and ScanSAR, requires substantial modifications to standard focusing methods due to the particular spectral properties of these data. Anticipating on this potential difficulty for non-expert users, the European Space Agency has chosen to release Sentinel-1 TOPS data in a Single Look Complex format (level 1). The data are already focused using state-of-the-art processing techniques, with phase information preserved. Even so, the focusing method introduces an additional quadratic phase term in the azimuth direction. In case of a small misregistration error between a pair of images, this residual term leads to steep phase ramps in azimuth that are superimposed on the desired interferometric phase. Therefore, this quadratic phase term needs to be removed from the SLC data prior to interferogram calculation. Here, a pre-processing method allowing for compensating this phase term and simply feeding the corrected SLC data into a standard InSAR processing chain is described. The method consists of three steps. The first step uses the metadata in order to reconstruct a continuous image in the azimuth direction, accounting for the small overlap between adjacent bursts (“stitching”). In the second step, multiplication of the images by an appropriate phase screen is performed so as to cancel the azimuthal quadratic phase term (“deramping”). The deramping operation uses the metadata, as well as the azimuth time lag between the images deduced from sub-pixel image correlation, in order to determine small misregistration errors. Misregistration errors are compensated using a simple affine relation deduced from least-square fitting of the azimuth offsets

  11. X-ray-generated ultrasonic signals - Characteristics and imaging applications

    NASA Astrophysics Data System (ADS)

    Sachse, W.; Kim, K. Y.; Pierce, W. F.

    1986-09-01

    Experiments dealing with the characterization of X-ray-generated ultrasonic signals in materials and their application to the imaging of material inhomogeneities are described. A linear relationship is established between the X-ray photon power and the generated ultrasonic signals. The directivity of the X-ray/acoustic source was found to resemble that of other thermoelastic sources. A new double-modulation measurement technique is described in which the magnitude and phase of the modulated acoustic signals are measured. Use of the technique is explored with various materials, incident beam sizes, and inclusions. The results of preliminary imaging experiments are described which were carried out with direct and double-modulated X-ray/acoustic signals. It is shown from these results that using the images generated at two modulation frequencies, identification of the spatial inhomogeneities in a specimen is possible.

  12. Preparation of a Versatile Bifunctional Zeolite for Targeted Imaging Applications

    PubMed Central

    Ndiege, Nicholas; Raidoo, Renugan; Schultz, Michael K.; Larsen, Sarah

    2011-01-01

    Bifunctional zeolite Y was prepared for use in targeted in vivo molecular imaging applications. The strategy involved functionalization of the external surface of zeolite Y with chloropropyltriethoxysilane followed by reaction with sodium azide to form azide-functionalized NaY, which is amenable to copper(1) catalyzed click chemistry. In this study, a model alkyne (4-pentyn-1-ol) was attached to the azide-terminated surface via click chemistry to demonstrate feasibility for attachment of molecular targeting vectors (e.g., peptides, aptamers) to the zeolite surface. The modified particle efficiently incorporates the imaging radioisotope gallium-68 (68Ga) into the pores of the azide-functionalized NaY zeolite to form a stable bifunctional molecular targeting vector. The result is a versatile “clickable” zeolite platform that can be tailored for future in vivo molecular targeting and imaging modalities. PMID:21306141

  13. Applications of magnetic resonance imaging in food science.

    PubMed

    Schmidt, S J; Sun, X; Litchfield, J B

    1996-04-01

    The physical and chemical changes that occur in foods during growth, harvest, processing, storage, preparation, and consumption are often very difficult to measure and quantify. Magnetic resonance imaging (MRI) is a pioneering technology, originally developed in the medical field, that is now being used in a large number of disciplines to study a wide variety of materials and processes. In food science, MRI techniques allow the interior of foods to be imaged noninvasively and nondestructively. These images can then be quantified to yield information about several processes and material properties, such as mass and heat transfer, fat and ice crystallization, gelation, water mobidity, composition and volume changes, food stability and maturation, flow behavior, and temperature. This article introduces the fundamental principles of MRI, presents some of the recent advances in MRI technology, and reviews some of the current applications of MRI in food science research.

  14. Adaptive optics and phase diversity imaging for responsive space applications.

    SciTech Connect

    Smith, Mark William; Wick, David Victor

    2004-11-01

    The combination of phase diversity and adaptive optics offers great flexibility. Phase diverse images can be used to diagnose aberrations and then provide feedback control to the optics to correct the aberrations. Alternatively, phase diversity can be used to partially compensate for aberrations during post-detection image processing. The adaptive optic can produce simple defocus or more complex types of phase diversity. This report presents an analysis, based on numerical simulations, of the efficiency of different modes of phase diversity with respect to compensating for specific aberrations during post-processing. It also comments on the efficiency of post-processing versus direct aberration correction. The construction of a bench top optical system that uses a membrane mirror as an active optic is described. The results of characterization tests performed on the bench top optical system are presented. The work described in this report was conducted to explore the use of adaptive optics and phase diversity imaging for responsive space applications.

  15. In vivo confocal imaging: general principles and applications.

    PubMed

    Petroll, W M; Jester, J V; Cavanagh, H D

    1994-01-01

    It is well established that confocal microscopy provides higher resolution images with better rejection of out-of-focus information than conventional light microscopy. The optical sectioning ability of confocal microscopy allows images to be obtained from different depths within a thick tissue specimen, thereby eliminating the need for processing and sectioning procedures. Thus, confocal microscopy has made it possible to view biological tissues under more physiologic conditions than previously possible. The most widespread biological application of confocal microscopy has been in the localization of immunofluorescently labeled proteins in cell culture or within excised blocks of tissue. Because of its noninvasive optical sectioning capability, confocal microscopy is also ideally suited to the study of tissue in intact living animals, although the potential in vivo applications of this paradigm have received less attention. In this paper we trace the development of in vivo confocal microscopy and present examples of current capabilities for both research and clinical use.

  16. Grid Computing Application for Brain Magnetic Resonance Image Processing

    NASA Astrophysics Data System (ADS)

    Valdivia, F.; Crépeault, B.; Duchesne, S.

    2012-02-01

    This work emphasizes the use of grid computing and web technology for automatic post-processing of brain magnetic resonance images (MRI) in the context of neuropsychiatric (Alzheimer's disease) research. Post-acquisition image processing is achieved through the interconnection of several individual processes into pipelines. Each process has input and output data ports, options and execution parameters, and performs single tasks such as: a) extracting individual image attributes (e.g. dimensions, orientation, center of mass), b) performing image transformations (e.g. scaling, rotation, skewing, intensity standardization, linear and non-linear registration), c) performing image statistical analyses, and d) producing the necessary quality control images and/or files for user review. The pipelines are built to perform specific sequences of tasks on the alphanumeric data and MRIs contained in our database. The web application is coded in PHP and allows the creation of scripts to create, store and execute pipelines and their instances either on our local cluster or on high-performance computing platforms. To run an instance on an external cluster, the web application opens a communication tunnel through which it copies the necessary files, submits the execution commands and collects the results. We present result on system tests for the processing of a set of 821 brain MRIs from the Alzheimer's Disease Neuroimaging Initiative study via a nonlinear registration pipeline composed of 10 processes. Our results show successful execution on both local and external clusters, and a 4-fold increase in performance if using the external cluster. However, the latter's performance does not scale linearly as queue waiting times and execution overhead increase with the number of tasks to be executed.

  17. Application of image processing techniques to fluid flow data analysis

    NASA Technical Reports Server (NTRS)

    Giamati, C. C.

    1981-01-01

    The application of color coding techniques used in processing remote sensing imagery to analyze and display fluid flow data is discussed. A minicomputer based color film recording and color CRT display system is described. High quality, high resolution images of two-dimensional data are produced on the film recorder. Three dimensional data, in large volume, are used to generate color motion pictures in which time is used to represent the third dimension. Several applications and examples are presented. System hardware and software is described.

  18. Imaging Radar Applications in the Death Valley Region

    NASA Technical Reports Server (NTRS)

    Farr, Tom G.

    1996-01-01

    Death Valley has had a long history as a testbed for remote sensing techniques (Gillespie, this conference). Along with visible-near infrared and thermal IR sensors, imaging radars have flown and orbited over the valley since the 1970's, yielding new insights into the geologic applications of that technology. More recently, radar interferometry has been used to derive digital topographic maps of the area, supplementing the USGS 7.5' digital quadrangles currently available for nearly the entire area. As for their shorter-wavelength brethren, imaging radars were tested early in their civilian history in Death Valley because it has a variety of surface types in a small area without the confounding effects of vegetation. In one of the classic references of these early radar studies, in a semi-quantitative way the response of an imaging radar to surface roughness near the radar wavelength, which typically ranges from about 1 cm to 1 m was explained. This laid the groundwork for applications of airborne and spaceborne radars to geologic problems in and regions. Radar's main advantages over other sensors stems from its active nature- supplying its own illumination makes it independent of solar illumination and it can also control the imaging geometry more accurately. Finally, its long wavelength allows it to peer through clouds, eliminating some of the problems of optical sensors, especially in perennially cloudy and polar areas.

  19. Applications of NMR imaging on solid rocket motor materials

    NASA Astrophysics Data System (ADS)

    Vanderheiden, E. J.

    An effort has been made to ascertain the applicability of nuclear magnetic resonance imaging (NMRI) to the inspection of solid rocket motors with graphite fiber-reinforced composite casings. The spatial resolution for small samples was about 100 cu microns. The graphite fibers were found to dramatically reduce the NMRI signal intensity; this effect was partially compensated for by using a probe inserted within the motor's bore as the receiver.

  20. A hyperspectral image data exploration workbench for environmental science applications

    SciTech Connect

    Woyna, M.A.; Christiansen, J.H.; Zawada, D.G.; Simunich, K.L.

    1994-08-01

    The Hyperspectral Image Data Exploration Workbench (HIDEW) software system has been developed by Argonne National Laboratory to enable analysts at Unix workstations to conveniently access and manipulate high-resolution imagery data for analysis, mapping purposes, and input to environmental modeling applications. HIDEW is fully object-oriented, including the underlying database. This system was developed as an aid to site characterization work and atmospheric research projects.

  1. A precision interferometric optical heterogeneity mapping system

    NASA Astrophysics Data System (ADS)

    Edgar, Gerard

    The object of this work was to design and build an instrument for mapping optical heterogeneities in fused silica blocks, with a sensitivity at least an order of magnitude better than any system currently available (prompted by a requirement of the Stanford Gravity Probe B project). The sources of inhomogeneities and the environment for containing these blocks to achieve measurements at this level are discussed with the implications for the instrument design. After a review of homogeneity testing methods, it was decided to develop an instrument system for use with several measurement methods. The most sensitive of these methods was selected to be fully developed in order to realise the measurement aim, the others being facilitated in the design. The design and development of a novel mechanically scanned heterodyne interferometric mapping system is described-following an error budget driven methodology. The critical 1mK thermally stable environment required for the liquid immersion measurement method employed, was exceeded by the design and development of a large computer controlled thermal enclosure to house the whole instrument system-sub-millidegree stabiliy achieved over periods of hours. Also described is the computer integration and software for execution and co-ordination of all measurements. The developed system meets the initial aim, being capable of an optical heterogeneity measurement sensitivity of 5 x 10-8 in refractive index in a 50mm thick sample. This was calibrated indirectly in a comparison with a Talystep surface profiling instrument. Further development work suggested could enhance this sensitivity by another factor of two.

  2. Liquid refractometer based on interferometric fringe projection

    NASA Astrophysics Data System (ADS)

    de Angelis, M.; De Nicola, S.; Ferraro, P.; Finizio, A.; Pierattini, G.

    2000-03-01

    Measurement of the refractive index of liquids is of great importance in applications such as the control of adulteration of liquids and pollution monitoring. We present and discuss a fringe projection technique for measuring the index of refraction of transparent liquid materials. In the proposed technique a fringe pattern produced by a reflective grating interferometer is imaged by a lens before passing through a cell containing the liquid sample under test. The interference pattern consists of a family of parallel straight fringes that are digitized by a CCD array. The focal shift, which is induced by the liquid sample, produces changes in the spatial frequency of the projected pattern. Spatial frequency of the fringe pattern is analysed by means of a one-dimensional Fourier transform and phase demodulation procedure. The principle of the proposed fringe projection refractometer relies on a comparative measurements of the refractive index of the sample under test with respect to a reference liquid. The method is simple and can be easily interpreted geometrically.

  3. Engineered Biocompatible Nanoparticles for in Vivo Imaging Applications

    PubMed Central

    2010-01-01

    Iron−platinum alloy nanoparticles (FePt NPs) are extremely promising candidates for the next generation of contrast agents for magnetic resonance (MR) diagnostic imaging and MR-guided interventions, including hyperthermic ablation of solid cancers. FePt has high Curie temperature, saturation magnetic moment, magneto-crystalline anisotropy, and chemical stability. We describe the synthesis and characterization of a family of biocompatible FePt NPs suitable for biomedical applications, showing and discussing that FePt NPs can exhibit low cytotoxicity. The importance of engineering the interface of strongly magnetic NPs using a coating allowing free aqueous permeation is demonstrated to be an essential parameter in the design of new generations of diagnostic and therapeutic MRI contrast agents. We report effective cell internalization of FePt NPs and demonstrate that they can be used for cellular imaging and in vivo MRI applications. This opens the way for several future applications of FePt NPs, including regenerative medicine and stem cell therapy in addition to enhanced MR diagnostic imaging. PMID:20919679

  4. Application of acute stroke imaging: selecting patients for revascularization therapy.

    PubMed

    Shang, Tiesong; Yavagal, Dileep R

    2012-09-25

    Due to the dynamic and versatile characteristics of ischemic penumbra, selecting the right acute ischemic stroke (AIS) patients for revascularization therapy (RT) based on initial available imaging can be challenging. The main patient selection criterion for RT is the size of the mismatch between the potentially salvageable tissue (penumbra) and the irreversibly damaged tissue (core). The goal of revascularization RT is to "freeze" the core and prevent it from extending to the penumbral tissue. Penumbral imaging selection of AIS patients for RT, using magnetic resonance or CT-based studies, may provide more clinical benefit to the appropriate patients, although direct evidence is pending. Not all penumbra-core mismatches beyond 3 hours are equal and need treatment, and defining which mismatches to target for RT is the current goal of ongoing clinical trials. In addition to "penumbral"-based imaging, large vessel occlusion and clot length estimation based on CT angiography and noncontrasted ultrathin CT scan has been used to identify patients who are refractory to systemic thrombolysis and may be eligible for endovascular therapy. The application of various imaging modalities in selecting and triaging AIS patients for RT is discussed in this review. Larger prospective randomized trials are needed to better understand the role of various imaging modalities in selecting AIS patients for RT and to understand its influence on clinical outcome.

  5. Image Description with Local Patterns: An Application to Face Recognition

    NASA Astrophysics Data System (ADS)

    Zhou, Wei; Ahrary, Alireza; Kamata, Sei-Ichiro

    In this paper, we propose a novel approach for presenting the local features of digital image using 1D Local Patterns by Multi-Scans (1DLPMS). We also consider the extentions and simplifications of the proposed approach into facial images analysis. The proposed approach consists of three steps. At the first step, the gray values of pixels in image are represented as a vector giving the local neighborhood intensity distrubutions of the pixels. Then, multi-scans are applied to capture different spatial information on the image with advantage of less computation than other traditional ways, such as Local Binary Patterns (LBP). The second step is encoding the local features based on different encoding rules using 1D local patterns. This transformation is expected to be less sensitive to illumination variations besides preserving the appearance of images embedded in the original gray scale. At the final step, Grouped 1D Local Patterns by Multi-Scans (G1DLPMS) is applied to make the proposed approach computationally simpler and easy to extend. Next, we further formulate boosted algorithm to extract the most discriminant local features. The evaluated results demonstrate that the proposed approach outperforms the conventional approaches in terms of accuracy in applications of face recognition, gender estimation and facial expression.

  6. Application of Perona Malik anisotropic diffusion on digital radiographic image

    SciTech Connect

    Halim, Suhaila Abd; Razak, Rohayu Abdul; Ibrahim, Arsmah; Manurung, Yupiter HP

    2014-07-10

    Perona Malik Anisotropic Diffusion (PMAD) is a very useful and efficient denoising technique if the parameters are properly selected. Overestimating the parameters may cause oversmoothed and underestimating it may leave unfiltered noise. This makes the selection of parameters a crucial process. In this paper the PMAD model is solved using a finite difference scheme The discretized model is evaluated using different diffusion coefficient of exponential and quadratic on defective radiographic images in terms of quality and efficiency. In the application of the PMAD model on image data, a set of defective radiographic images of welding is used as input data. Peak Signal to Noise Ratio (PSNR), Structural Similarity Measure (SSIM) and temporal time are used to evaluate the performance of the model. The implementation of the experiment has been carried out using MATLAB R2009a. In terms of quality, results show that the Quadratic Diffusion Coefficient Function (QDCF) provides better results compared with the Exponential Diffusion Coefficient Function (EDCF). In conclusion, the denoising effect using PMAD model based on finite difference scheme shows able to improve image quality by removing noise in the defective radiographic image.

  7. Nuclear molecular imaging with nanoparticles: radiochemistry, applications and translation

    PubMed Central

    Abou, D S; Pickett, J E

    2015-01-01

    Molecular imaging provides considerable insight into biological processes for greater understanding of health and disease. Numerous advances in medical physics, chemistry and biology have driven the growth of this field in the past two decades. With exquisite sensitivity, depth of detection and potential for theranostics, radioactive imaging approaches have played a major role in the emergence of molecular imaging. At the same time, developments in materials science, characterization and synthesis have led to explosive progress in the nanoparticle (NP) sciences. NPs are generally defined as particles with a diameter in the nanometre size range. Unique physical, chemical and biological properties arise at this scale, stimulating interest for applications as diverse as energy production and storage, chemical catalysis and electronics. In biomedicine, NPs have generated perhaps the greatest attention. These materials directly interface with life at the subcellular scale of nucleic acids, membranes and proteins. In this review, we will detail the advances made in combining radioactive imaging and NPs. First, we provide an overview of the NP platforms and their properties. This is followed by a look at methods for radiolabelling NPs with gamma-emitting radionuclides for use in single photon emission CT and planar scintigraphy. Next, utilization of positron-emitting radionuclides for positron emission tomography is considered. Finally, recent advances for multimodal nuclear imaging with NPs and efforts for clinical translation and ongoing trials are discussed. PMID:26133075

  8. Applications of Aptamers in Targeted Imaging: State of the Art

    PubMed Central

    Dougherty, Casey A.; Cai, Weibo; Hong, Hao

    2015-01-01

    Aptamers are single-stranded oligonucleotides with high affinity and specificity to the target molecules or cells, thus they can serve as an important category of molecular targeting ligand. Since their discove1y, aptamers have been rapidly translated into clinical practice. The strong target affinity/selectivity, cost-effectivity, chemical versatility and safety of aptamers are superior to traditional peptides- or proteins-based ligands which make them unique choices for molecular imaging. Therefore, aptamers are considered to be extremely useful to guide various imaging contrast agents to the target tissues or cells for optical, magnetic resonance, nuclear, computed tomography, ultra sound and multimodality imaging. This review aims to provide an overview of aptamers' advantages as targeting ligands and their application in targeted imaging. Further research in synthesis of new types of aptamers and their conjugation with new categories of contrast agents is required to develop clinically translatable aptamer-based imaging agents which will eventually result in improved patient care. PMID:25866268

  9. Applicability of radio astronomy techniques to the processing and interpretation of aperture synthesis passive millimetre-wave applications

    NASA Astrophysics Data System (ADS)

    Taylor, Christopher T.; Wilkinson, Peter N.; Salmon, Neil A.; Cameron, Colin D.

    2012-06-01

    This PhD programme is contributing to the development of Passive Millimetre-Wave Imagers (PMMWI) using the principles of interferometric aperture synthesis and digital signal processing. The principal applications are security screening, all-weather flight aids and earth observation. To enhance the cost-effectiveness of PMMWI systems the number of collecting elements must be minimised whilst maintaining adequate image fidelity. A wide range of techniques have been developed by the radio astronomy community for improving the fidelity of sparse interferometric array imagery. This paper brings to the attention of readers these techniques and discusses how they may be applied to imaging using software packages publicly available from the radio astronomy community. The intention of future work is to adapt these algorithms to process experimental data from a range of realistic simulations and real-world targets.

  10. HuntIR thermal imagers for reconnaissance and targeting applications

    NASA Astrophysics Data System (ADS)

    Breiter, Rainer; Cabanski, Wolfgang A.; Ihle, Tobias; Mauk, Karl-Heinz; Rode, Werner

    2004-08-01

    A new family of light handheld military thermal imagers for reconnaissance and targeting applications was developed based on AIM's IR components like IR detection modules, command and control electronics and image processing units. Three different types of imagers provide solutions for different requirements in identification ranges of targets. The highest performance device makes use of a FPA MCT 384x288 MWIR detector with a motorized double field of view optics. An identification range up to 2400m for the NATO standard target was proven according to the FGAN-FOM TRM3 range model. The device provides a mechanical adaptation to weapon systems and provides target markers for common hand weapons of the German army. A single field of view MCT device for 1000m ranges and an uncooled device on the lower performance end complete the imager family. Electronics for intelligent power management from batteries and display electronics were developed to provide stand alone operation. The modular concept allows the use of the same image processing unit for all devices providing special features for best performance like scene-based non-uniformity correction together with an optical calibration element and dynamic reduction including automatic histogram equalization for optimized scene display and text or graphics overlay. Due to the modular concept the components like the image processing unit are already used and validated in programs like the thermal sight for the self defense gun of the reconnaissance vehicle FENNEK together with a 320x240 LWIR uncooled microbolometer detector or with the MCT 384x288 MWIR detection module in a thermal imager for the German army UAV Luna.

  11. Application of side-oblique image-motion blur correction to Kuaizhou-1 agile optical images.

    PubMed

    Sun, Tao; Long, Hui; Liu, Bao-Cheng; Li, Ying

    2016-03-21

    Given the recent development of agile optical satellites for rapid-response land observation, side-oblique image-motion (SOIM) detection and blur correction have become increasingly essential for improving the radiometric quality of side-oblique images. The Chinese small-scale agile mapping satellite Kuaizhou-1 (KZ-1) was developed by the Harbin Institute of Technology and launched for multiple emergency applications. Like other agile satellites, KZ-1 suffers from SOIM blur, particularly in captured images with large side-oblique angles. SOIM detection and blur correction are critical for improving the image radiometric accuracy. This study proposes a SOIM restoration method based on segmental point spread function detection. The segment region width is determined by satellite parameters such as speed, height, integration time, and side-oblique angle. The corresponding algorithms and a matrix form are proposed for SOIM blur correction. Radiometric objective evaluation indices are used to assess the restoration quality. Beijing regional images from KZ-1 are used as experimental data. The radiometric quality is found to increase greatly after SOIM correction. Thus, the proposed method effectively corrects image motion for KZ-1 agile optical satellites.

  12. Application of image visual characterization and soft feature selection in content-based image retrieval

    NASA Astrophysics Data System (ADS)

    Jarrah, Kambiz; Kyan, Matthew; Lee, Ivan; Guan, Ling

    2006-01-01

    Fourier descriptors (FFT) and Hu's seven moment invariants (HSMI) are among the most popular shape-based image descriptors and have been used in various applications, such as recognition, indexing, and retrieval. In this work, we propose to use the invariance properties of Hu's seven moment invariants, as shape feature descriptors, for relevance identification in content-based image retrieval (CBIR) systems. The purpose of relevance identification is to find a collection of images that are statistically similar to, or match with, an original query image from within a large visual database. An automatic relevance identification module in the search engine is structured around an unsupervised learning algorithm, the self-organizing tree map (SOTM). In this paper we also proposed a new ranking function in the structure of the SOTM that exponentially ranks the retrieved images based on their similarities with respect to the query image. Furthermore, we propose to extend our studies to optimize the contribution of individual feature descriptors for enhancing the retrieval results. The proposed CBIR system is compatible with the different architectures of other CBIR systems in terms of its ability to adapt to different similarity matching algorithms for relevance identification purposes, whilst offering flexibility of choice for alternative optimization and weight estimation techniques. Experimental results demonstrate the satisfactory performance of the proposed CBIR system.

  13. Application of side-oblique image-motion blur correction to Kuaizhou-1 agile optical images.

    PubMed

    Sun, Tao; Long, Hui; Liu, Bao-Cheng; Li, Ying

    2016-03-21

    Given the recent development of agile optical satellites for rapid-response land observation, side-oblique image-motion (SOIM) detection and blur correction have become increasingly essential for improving the radiometric quality of side-oblique images. The Chinese small-scale agile mapping satellite Kuaizhou-1 (KZ-1) was developed by the Harbin Institute of Technology and launched for multiple emergency applications. Like other agile satellites, KZ-1 suffers from SOIM blur, particularly in captured images with large side-oblique angles. SOIM detection and blur correction are critical for improving the image radiometric accuracy. This study proposes a SOIM restoration method based on segmental point spread function detection. The segment region width is determined by satellite parameters such as speed, height, integration time, and side-oblique angle. The corresponding algorithms and a matrix form are proposed for SOIM blur correction. Radiometric objective evaluation indices are used to assess the restoration quality. Beijing regional images from KZ-1 are used as experimental data. The radiometric quality is found to increase greatly after SOIM correction. Thus, the proposed method effectively corrects image motion for KZ-1 agile optical satellites. PMID:27136855

  14. Continuous monitoring of biophysical Eucalyptus sp. parameters using interferometric synthetic aperture radar data in P and X bands

    NASA Astrophysics Data System (ADS)

    Gama, Fábio Furlan; dos Santos, João Roberto; Mura, José Claudio

    2016-04-01

    This work aims to verify the applicability of models obtained using interferometric synthetic aperture radar (SAR) data for estimation of biophysical Eucalyptus saligna parameters [diameter of breast height (DBH), total height and volume], as a method of continuous forest inventory. In order to obtain different digital elevation models, and the interferometric height (Hint) to retrieve the tree heights, SAR surveying was carried out by an airborne interferometric SAR in two frequencies X and P bands. The study area, located in the Brazilian southeast region (S 22°53‧22″/W 45°26‧16″ and S 22°53‧22″/W 45°26‧16″), comprises 128.64 hectares of Eucalyptus saligna stands. The methodological procedures encompassed: forest inventory, topographic surveying, radar mapping, radar processing, and multivariable regression techniques to build Eucalyptus volume, DBH, and height models. The statistical regression pointed out Hint and interferometric coherence as the most important variables for the total height and DBH estimation; for the volume model, however, only the Hint variable was selected. The performance of the biophysical models from the second campaign, two years later (2006), were consistent and its results are very promising for updating annual inventories needed for managing Eucalyptus plantations.

  15. A review of controlled-source electromagnetic science applications and opportunities for imaging in the depth range 20 m to 1 km (Invited)

    NASA Astrophysics Data System (ADS)

    Everett, M. E.

    2009-12-01

    There are many exciting geoscience opportunities available to those who can provide three—dimensional subsurface characterization within the 20 m—1.0 km depth range. Applications include gas hydrates and permafrost; climate change proxy signatures in the stratigraphic record; shoreline shaping processes; glacier and ice—sheet mass transport; watershed—scale and coastal hydrology including seawater intrusion; fault—zone characterization; Earth’s tectonic, volcanic, and extraterrestrial impact history; landslide hazard assessment; carbon sequestration; characterization of geothermal systems. Many of the aforementioned science applications can and have been addressed using various geophysical techniques. The shallower depth range is very suitable to multi—electrode resistivity imaging, which has seen a tremendous resurgence of late thanks to newly developed instrumentation. Ground—penetrating radar signals provide high—resolution subsurface images but they attenuate rapidly with depth and hence, except in special cases, do not probe beneath 20 m. Seismic reflection and refraction studies, using artificial sources, earthquakes and ambient noise, supplemented with newer surface wave and interferometric methods, are the traditional workhorse for the 20 m - 1.0 km depth range. Gravity and magnetic techniques continue to see great improvements and have long provided valuable subsurface information, when either used alone or in conjunction with another method. Other geophysical techniques such as spontaneous potential, induced polarization, and electroseismic are also gaining in importance. Controlled—source electromagnetics occupies an important niche for 20 m -1.0 km depth investigations as a complement to seismic and as an active technique that permits both parametric (variable frequency, or time—domain equivalent) and geometric (variable source—receiver separations) soundings. Low—frequency (sub—kHz) electromagnetic induction signals

  16. Bioanalytical Applications of Real-Time ATP Imaging Via Bioluminescence

    SciTech Connect

    Jason Alan Gruenhagen

    2003-12-12

    The research discussed within involves the development of novel applications of real-time imaging of adenosine 5'-triphosphate (ATP). ATP was detected via bioluminescence and the firefly luciferase-catalyzed reaction of ATP and luciferin. The use of a microscope and an imaging detector allowed for spatially resolved quantitation of ATP release. Employing this method, applications in both biological and chemical systems were developed. First, the mechanism by which the compound 48/80 induces release of ATP from human umbilical vein endothelial cells (HUVECs) was investigated. Numerous enzyme activators and inhibitors were utilized to probe the second messenger systems involved in release. Compound 48/80 activated a G{sub q}-type protein to initiate ATP release from HUVECs. Ca{sup 2+} imaging along with ATP imaging revealed that activation of phospholipase C and induction of intracellular Ca{sup 2+} signaling were necessary for release of ATP. Furthermore, activation of protein kinase C inhibited the activity of phospholipase C and thus decreased the magnitude of ATP release. This novel release mechanism was compared to the existing theories of extracellular release of ATP. Bioluminescence imaging was also employed to examine the role of ATP in the field of neuroscience. The central nervous system (CNS) was dissected from the freshwater snail Lymnaea stagnalis. Electrophysiological experiments demonstrated that the neurons of the Lymnaea were not damaged by any of the components of the imaging solution. ATP was continuously released by the ganglia of the CNS for over eight hours and varied from ganglion to ganglion and within individual ganglia. Addition of the neurotransmitters K{sup +} and serotonin increased release of ATP in certain regions of the Lymnaea CNS. Finally, the ATP imaging technique was investigated for the study of drug release systems. MCM-41-type mesoporous nanospheres were loaded with ATP and end-capped with mercaptoethanol functionalized Cd

  17. Uncooled microbolometer thermal imaging sensors for unattended ground sensor applications

    NASA Astrophysics Data System (ADS)

    Figler, Burton D.

    2001-09-01

    Starting in the early 1990's, uncooled microbolometer thermal imaging sensor technology began to move out of the basic development laboratories of the Honeywell Corporation in Minneapolis and into applied development at several companies which have licensed the basic technology. Now, this technology is addressing military, government, and commercial applications in the real world. Today, thousands of uncooled microbolometer thermal imaging sensors are being produced and sold annually. At the same time, applied research and development on the technology continues at an unabated pace. These research and development efforts have two primary goals: 1) improving sensor performance in terms of increased resolution and greater thermal sensitivity and 2) reducing sensor cost. Success is being achieved in both areas. In this paper we will describe advances in uncooled microbolometer thermal imaging sensor technology as they apply to the modern battlefield and to unattended ground sensor applications in particular. Improvements in sensor performance include: a) reduced size, b) increased spatial resolution, c) increased thermal sensitivity, d) reduced electrical power, and e) reduced weight. For battlefield applications, unattended sensors are used not only in fixed ground locations, but also on a variety of moving platforms, including remotely operated ground vehicles, as well as Micro and Miniature Aerial Vehicles. The use of uncooled microbolometer thermal imaging sensors on these platforms will be discussed, and the results from simulations, of an uncooled microbolometer sensor flying on a Micro Aerial Vehicle will be presented. Finally, we will describe microbolometer technology advancements currently being made or planned at BAE SYSTEMS. Where possible, examples of actual improvements, in the form of real imagery and/or actual performance measurements, will be provided.

  18. Development of a hyperspectral fluorescence lifetime imaging microscope and its application to tissue imaging

    NASA Astrophysics Data System (ADS)

    Owen, Dylan M.; Manning, Hugh B.; de Beule, Pieter; Talbot, Clifford; Requejo-Isidro, Jose; Dunsby, Chris; McGinty, James; Benninger, Richard K. P.; Elson, Dan S.; Munro, Ian; Galletly, Neil P.; Lever, M. Jon; Stamp, Gordon W.; Anand, Praveen; Neil, Mark A. A.; French, Paul M. W.

    2007-02-01

    We present the design, characterization and application of a novel, rapid, optically sectioned hyperspectral fluorescence lifetime imaging (FLIM) microscope. The system is based on a line scanning confocal configuration and uses a highspeed time-gated detector to extract lifetime information from many pixels in parallel. This allows the full spectraltemporal profiles of a fluorescence decay to be obtained from every pixel in an image. Line illumination and slit detection also gives the microscope a confocal optical sectioning ability. The system is applied to test samples and unstained biological tissue. In future, this microscope will be combined with recently-developed continuously electronically tunable, pulsed light sources based on tapered, micro-structured optical fibers. This will allow hyperspectral FLIM to be combined with the advantages of excitation spectroscopy to gain further insight into complex biological specimens including tissue and live cell imaging.

  19. Application of independent component analysis in face images: a survey

    NASA Astrophysics Data System (ADS)

    Huang, Yuchi; Lu, Hanqing

    2003-09-01

    Face technologies which can be applied to access control and surveillance, are essential to intelligent vision-based human computer interaction. The research efforts in this field include face detecting, face recognition, face retrieval, etc. However, these tasks are challenging because of variability in view point, lighting, pose and expression of human faces. The ideal face representation should consider the variability so as to we can develop robust algorithms for our applications. Independent Component Analysis (ICA) as an unsupervised learning technique has been used to find such a representation and obtained good performances in some applications. In the first part of this paper, we depict the models of ICA and its extensions: Independent Subspace Analysis (ISA) and Topographic ICA (TICA).Then we summaraize the process in the applications of ICA and its extension in Face images. At last we propose a promising direction for future research.

  20. Radar image and data fusion for natural hazards characterisation

    USGS Publications Warehouse

    Lu, Zhong; Dzurisin, Daniel; Jung, Hyung-Sup; Zhang, Jixian; Zhang, Yonghong

    2010-01-01

    Fusion of synthetic aperture radar (SAR) images through interferometric, polarimetric and tomographic processing provides an all - weather imaging capability to characterise and monitor various natural hazards. This article outlines interferometric synthetic aperture radar (InSAR) processing and products and their utility for natural hazards characterisation, provides an overview of the techniques and applications related to fusion of SAR/InSAR images with optical and other images and highlights the emerging SAR fusion technologies. In addition to providing precise land - surface digital elevation maps, SAR - derived imaging products can map millimetre - scale elevation changes driven by volcanic, seismic and hydrogeologic processes, by landslides and wildfires and other natural hazards. With products derived from the fusion of SAR and other images, scientists can monitor the progress of flooding, estimate water storage changes in wetlands for improved hydrological modelling predictions and assessments of future flood impacts and map vegetation structure on a global scale and monitor its changes due to such processes as fire, volcanic eruption and deforestation. With the availability of SAR images in near real - time from multiple satellites in the near future, the fusion of SAR images with other images and data is playing an increasingly important role in understanding and forecasting natural hazards.

  1. Quantitative interferometric microscopy with improved full-field phase aberration compensation

    NASA Astrophysics Data System (ADS)

    Xue, Liang; Wang, Shouyu; Yan, Keding; Sun, Nan; Li, Zhenhua; Liu, Fei

    2014-11-01

    Single-shot quantitative interferometric microscopy (QIM) needs a high-accuracy and rapid phase retrieval algorithm. Retrieved phase distributions are often influenced by phase aberration background caused by both imaging system and phase retrieval algorithms. Here, we propose an improved phase aberration compensation (PAC) approach in order to eliminate the phase aberrations inherent in the data. With this method, sample-free parts are identified and used to calculate the background phase, reducing phase errors induced in samples and providing high-quality phase images. We now demonstrate that QIM based on this PAC approach realizes high-quality phase imaging from a single interferogram. This is of great potential for a real-time speedy diagnosis.

  2. Indocyanine Green Loaded Nanoconstructs for Optical Imaging and Phototherapeutic Applications

    NASA Astrophysics Data System (ADS)

    Bahmani, Baharak

    Development of theranostic nano-constructs may enable diagnosis and treatment of diseases at high spatial resolution. Optically active nanoparticles are widely pursued as exogenous chromophores in diagnostic imaging and phototherapeutic applications. However, the blood circulation time of nanoparticles remains limited due to the rapid clearance of the nanoparticles by reticuloendothelial system (RES). Coating with Polyethylene glycol (PEG) is a strategy to extend the circulation time of nanoparticles. Here, we report PEGylation of polymeric-based nanocapsules loaded with Indocyanine green (ICG) and effect of PEG's molecular weight on the uptake of these nanocapsules by human spleen macrophages and hepatocytes using flow cytometry. To characterize the biodistribution of the constructs, we performed in vivo quantitative fluorescence imaging in mice and subsequently analyzed the various extracted organs. Our results suggest that encapsulation of ICG in these PEGylated constructs is an effective approach to prolong the circulation time of ICG and delay its hepatic accumulation. Increased bioavailability of ICG, offers the potential of extending the clinical applications of ICG. Targeted delivery of therapeutic and imaging agents using surface modified nanovectors has been explored immensely in recent years. The growing demand for site-specific and efficient delivery of nanovectors entails stable surface conjugation of targeting moieties. Our ICG-loaded polymeric nanocapsules (ICG-NCs) have potential for covalent coupling of various targeting moieties and materials due to presence of amine groups on the surface. Here, we covalently bioconjugate PEG-coated ICG-NCs with monoclonal anti- HER2 through reductive amination-mediated procedures. The targeting abilities of HER2 functionalized ICG-NCs toward ovarian cancer was investigated in-vitro. Since these functionalized nanoconstructs have potential applications in laser-induced photodestruction of ovarian cancer cells, we

  3. Optomechanical correlations and signal self-amplification in interferometric measurements

    NASA Astrophysics Data System (ADS)

    Cohadon, P.-F.; Verlot, P.; Tavernarakis, A.; Briant, T.; Heidmann, A.

    2010-05-01

    Radiation pressure exerted by light in interferometric measurements is responsible for displacements of mirrors which appear as an additional back-action noise and limit the sensitivity of the measurement. We experimentally study these effects by monitoring in a very high-finesse optical cavity the displacements of a mirror with a sensitivity at the 10-20 m/ level. This very high sensitivity is a step towards the observation of fundamental quantum effects of radiation pressure such as the standard quantum limit in interferometric measurements. We report the observation of optomechanical correlations between two optical beams sent into the same moving mirror cavity. We also observed a self-amplification of a signal, which is a consequence of dynamical back-action of radiation pressure in a detuned cavity, and may improve the interferometric measurement sensitivity beyond the standard quantum limit.

  4. Atom-interferometric measurement of Stark level splittings

    NASA Astrophysics Data System (ADS)

    Zhao, Jianming; Raithel, Georg

    2016-05-01

    Rydberg atoms are highly sensitive to external electric fields due to their large polarizability, scaling as n7 (n is the principal quantum number). In cesium, nS Rydberg levels mix with nearby (n-4) high- l states, forming sequences of avoided crossings. Mixed adiabatic/diabatic passages through these crossings are employed as beam splitters and recombiners in an atom-interferometric measurement of energy level splittings. We subject cold cesium atoms to laser-excitation, electric-field and detection sequences that constitute an (internal-state) atom interferometer. For the read-out of the interferometer we utilize state-dependent collisions, which selectively remove atoms of one kind from the detected signal. We investigate the dependence of the interferometric signal on timing and field parameters, and find good agreement with quantum simulations of the interferometer. Fourier analysis of the interferometric signals yield coherence frequencies that agree with corresponding energy-level differences in calculated Stark maps.

  5. Gaussian interferometric power and Black box estimation of Unruh temperature

    NASA Astrophysics Data System (ADS)

    Wang, Jieci; Cao, Haixin; Jing, Jiliang

    2016-10-01

    We present a black box estimation paradigm of Unruh temperature in a relativistic bosonic continuous-variable setting. It is shown that the guaranteed precision for the estimation of Unruh temperature can be evaluated by the Gaussian interferometric power for a given probe state. We demonstrate that the amount of interferometric power is always beyond the entanglement type quantum correlations in a relativistic setting. It is found that due to the fact that Unruh radiation acts as a thermal bath on the probe system, it destroys available resources of the probe system and reduces the guaranteed precision of the estimation of Unruh temperature. We also find that the thermal noise induced by Unruh effect will generate interferometric power between accelerated Bob and his auxiliary partner anti-Bob, while it does not generate any correlation between inertial Alice and anti-Bob.

  6. Refractive index compensation in over-determined interferometric systems.

    PubMed

    Lazar, Josef; Holá, Miroslava; Číp, Ondřej; Čížek, Martin; Hrabina, Jan; Buchta, Zdeněk

    2012-10-19

    We present an interferometric technique based on a differential interferometry setup for measurement under atmospheric conditions. The key limiting factor in any interferometric dimensional measurement are fluctuations of the refractive index of air representing a dominating source of uncertainty when evaluated indirectly from the physical parameters of the atmosphere. Our proposal is based on the concept of an over-determined interferometric setup where a reference length is derived from a mechanical frame made from a material with a very low thermal coefficient. The technique allows one to track the variations of the refractive index of air on-line directly in the line of the measuring beam and to compensate for the fluctuations. The optical setup consists of three interferometers sharing the same beam path where two measure differentially the displacement while the third evaluates the changes in the measuring range, acting as a tracking refractometer. The principle is demonstrated in an experimental setup.

  7. Measurement of Pancharatnam's phase by robust interferometric and polarimetric methods

    SciTech Connect

    Loredo, J. C.; Ortiz, O.; De Zela, F.; Weingaertner, R.

    2009-07-15

    We report on theoretical calculations and experimental observations of Pancharatnam's phase originating from arbitrary SU(2) transformations applied to polarization states of light. We have implemented polarimetric and interferometric methods, which allow us to cover the full Poincare sphere. As a distinctive feature, our interferometric array is robust against mechanical and thermal disturbances, showing that the polarimetric method is not inherently superior over the interferometric one, as previously assumed. Our strategy effectively amounts to feeding an interferometer with two copropagating beams that are orthogonally polarized with respect to each other. It can be applied to different types of standard arrays, such as a Michelson, a Sagnac, or a Mach-Zehnder interferometer. We exhibit the versatility of our arrangement by performing measurements of Pancharatnam's phases and fringe visibilities that closely fit the theoretical predictions. Our approach can be easily extended to deal with mixed states and to study decoherence effects.

  8. Design and applications of a multimodality image data warehouse framework.

    PubMed

    Wong, Stephen T C; Hoo, Kent Soo; Knowlton, Robert C; Laxer, Kenneth D; Cao, Xinhau; Hawkins, Randall A; Dillon, William P; Arenson, Ronald L

    2002-01-01

    A comprehensive data warehouse framework is needed, which encompasses imaging and non-imaging information in supporting disease management and research. The authors propose such a framework, describe general design principles and system architecture, and illustrate a multimodality neuroimaging data warehouse system implemented for clinical epilepsy research. The data warehouse system is built on top of a picture archiving and communication system (PACS) environment and applies an iterative object-oriented analysis and design (OOAD) approach and recognized data interface and design standards. The implementation is based on a Java CORBA (Common Object Request Broker Architecture) and Web-based architecture that separates the graphical user interface presentation, data warehouse business services, data staging area, and backend source systems into distinct software layers. To illustrate the practicality of the data warehouse system, the authors describe two distinct biomedical applications--namely, clinical diagnostic workup of multimodality neuroimaging cases and research data analysis and decision threshold on seizure foci lateralization. The image data warehouse framework can be modified and generalized for new application domains.

  9. Modulated digital images for biometric and other security applications

    NASA Astrophysics Data System (ADS)

    McCarthy, Lawry D.; Lee, Robert A.; Swiegers, Gerhard F.

    2004-06-01

    There are, in general, two ways for an observer to deal with light that is incorrect in some way (e.g. which is partially out of focus). One approach is to correct the error (e.g. by using a lens to selectively bend the light). Another approach employs selective masking to block those portions of the light which are unwanted (e.g. out of focus). The principle of selective masking is used in a number of important industries. However it has not found widespread application in the field of optical security devices. This work describes the selective masking, or modulation, of digital images as a means of creating documents and transparent media containing overt or covert biometric and other images. In particular, we show how animation effects, flash-illumination features, color-shifting patches, information concealment devices, and biometric portraiture in various settings can be incorporated in transparent media like plastic packaging materials, credit cards, and plastic banknotes. We also demonstrate the application of modulated digital images to the preparation of optically variable diffractive foils which are readily customized to display biometric portraits and information. Selective masking is shown to be an important means of creating a diverse range of effects useful in authentication. Such effects can be readily and inexpensively produced without the need, for example, to fabricate lenses on materials which may not be conducive in this respect.

  10. Autonomous control systems: applications to remote sensing and image processing

    NASA Astrophysics Data System (ADS)

    Jamshidi, Mohammad

    2001-11-01

    One of the main challenges of any control (or image processing) paradigm is being able to handle complex systems under unforeseen uncertainties. A system may be called complex here if its dimension (order) is too high and its model (if available) is nonlinear, interconnected, and information on the system is uncertain such that classical techniques cannot easily handle the problem. Examples of complex systems are power networks, space robotic colonies, national air traffic control system, and integrated manufacturing plant, the Hubble Telescope, the International Space Station, etc. Soft computing, a consortia of methodologies such as fuzzy logic, neuro-computing, genetic algorithms and genetic programming, has proven to be powerful tools for adding autonomy and semi-autonomy to many complex systems. For such systems the size of soft computing control architecture will be nearly infinite. In this paper new paradigms using soft computing approaches are utilized to design autonomous controllers and image enhancers for a number of application areas. These applications are satellite array formations for synthetic aperture radar interferometry (InSAR) and enhancement of analog and digital images.

  11. Measurements and analysis in imaging for biomedical applications

    NASA Astrophysics Data System (ADS)

    Hoeller, Timothy L.

    2009-02-01

    A Total Quality Management (TQM) approach can be used to analyze data from biomedical optical and imaging platforms of tissues. A shift from individuals to teams, partnerships, and total participation are necessary from health care groups for improved prognostics using measurement analysis. Proprietary measurement analysis software is available for calibrated, pixel-to-pixel measurements of angles and distances in digital images. Feature size, count, and color are determinable on an absolute and comparative basis. Although changes in images of histomics are based on complex and numerous factors, the variation of changes in imaging analysis to correlations of time, extent, and progression of illness can be derived. Statistical methods are preferred. Applications of the proprietary measurement software are available for any imaging platform. Quantification of results provides improved categorization of illness towards better health. As health care practitioners try to use quantified measurement data for patient diagnosis, the techniques reported can be used to track and isolate causes better. Comparisons, norms, and trends are available from processing of measurement data which is obtained easily and quickly from Scientific Software and methods. Example results for the class actions of Preventative and Corrective Care in Ophthalmology and Dermatology, respectively, are provided. Improved and quantified diagnosis can lead to better health and lower costs associated with health care. Systems support improvements towards Lean and Six Sigma affecting all branches of biology and medicine. As an example for use of statistics, the major types of variation involving a study of Bone Mineral Density (BMD) are examined. Typically, special causes in medicine relate to illness and activities; whereas, common causes are known to be associated with gender, race, size, and genetic make-up. Such a strategy of Continuous Process Improvement (CPI) involves comparison of patient results

  12. Near-field three-dimensional radar imaging techniques and applications.

    PubMed

    Sheen, David; McMakin, Douglas; Hall, Thomas

    2010-07-01

    Three-dimensional radio frequency imaging techniques have been developed for a variety of near-field applications, including radar cross-section imaging, concealed weapon detection, ground penetrating radar imaging, through-barrier imaging, and nondestructive evaluation. These methods employ active radar transceivers that operate at various frequency ranges covering a wide range, from less than 100 MHz to in excess of 350 GHz, with the frequency range customized for each application. Computational wavefront reconstruction imaging techniques have been developed that optimize the resolution and illumination quality of the images. In this paper, rectilinear and cylindrical three-dimensional imaging techniques are described along with several application results.

  13. Near-Field Three-Dimensional Radar Imaging Techniques and Applications

    SciTech Connect

    Sheen, David M.; McMakin, Douglas L.; Hall, Thomas E.

    2010-07-01

    Three dimensional radio frequency imaging techniques have been developed for a variety of near field applications including radar cross-section imaging, concealed weapon detection, ground penetrating radar imaging, through-barrier imaging, and non-destructive evaluation. These methods employ active radar transceivers that operate at various frequency ranges covering a wide range from less than 100 MHz to in excess of 350 GHz with the frequency range customized for each application. Computational wavefront reconstruction imaging techniques have been developed that optimize the resolution and illumination quality of the images. In this paper, rectilinear and cylindrical three-dimensional imaging techniques are described along with several application results.

  14. Biological visual attention guided automatic image segmentation with application in satellite imaging

    NASA Astrophysics Data System (ADS)

    Sina, M. I.; Cretu, A.-M.; Payeur, P.

    2012-03-01

    Taking inspiration from the significantly superior performance of humans to extract and interpret visual information, the exploitation of biological visual mechanisms can contribute to the improvement of the performance of computational image processing systems. Computational models of visual attention have already been shown to significantly improve the speed of scene understanding by attending only the regions of interest, while distributing the resources where they are required. However, there are only few attention-based computational systems that have been used in practical applications dealing with real data and up to now, none of the computational attention models was demonstrated to work under a wide range of image content, characteristics and scales such as those encountered in satellite imaging. This paper outlines some of the difficulties that the current generation of visual attention-inspired models encounter when dealing with satellite images. It then proposes a novel algorithm for automatic image segmentation and regions of interest search that combines elements of human visual attention with Legendre moments applied on the probability density function of color histograms. The experimental results demonstrate that the proposed approach obtains better results than one of the most evolved current computational attention model proposed in the literature.

  15. Scaling images using their background ratio. An application in statistical comparisons of images.

    PubMed

    Kalemis, A; Binnie, D; Bailey, D L; Flower, M A; Ott, R J

    2003-06-01

    Comparison of two medical images often requires image scaling as a pre-processing step. This is usually done with the scaling-to-the-mean or scaling-to-the-maximum techniques which, under certain circumstances, in quantitative applications may contribute a significant amount of bias. In this paper, we present a simple scaling method which assumes only that the most predominant values in the corresponding images belong to their background structure. The ratio of the two images to be compared is calculated and its frequency histogram is plotted. The scaling factor is given by the position of the peak in this histogram which belongs to the background structure. The method was tested against the traditional scaling-to-the-mean technique on simulated planar gamma-camera images which were compared using pixelwise statistical parametric tests. Both sensitivity and specificity for each condition were measured over a range of different contrasts and sizes of inhomogeneity for the two scaling techniques. The new method was found to preserve sensitivity in all cases while the traditional technique resulted in significant degradation of sensitivity in certain cases.

  16. Application of thermoacoustic computed tomography to breast imaging

    NASA Astrophysics Data System (ADS)

    Kruger, Robert A.; Kiser, William L., Jr.; Reinecke, Daniel R.; Kruger, Gabe A.

    1999-05-01

    Acoustic pressure waves are induced in soft tissue whenever time-varying radiation is absorbed. By recording these time- dependent pressure waves over a sufficient number of angles surrounding the tissue being imaged, it is possible to reconstruct the pattern of radiation absorption within the tissue in three dimensions with spatial resolution that is independent of the carrier frequency of the irradiating energy. We recently constructed the world's first thermoacoustic computed tomography (TACT) scanner, which exploits this physical interaction. Initial in vivo imaging of a human breast was performed using safe levels of 434 MHz radiation. Good soft tissue differentiation with 2 - 5 mm spatial resolution to a depth of 40 mm was achieved. The absorption properties of the breast and the irradiation pattern within the breast determined the TACT image contrast. The length of the RF pulse, the size of the transducers and their frequency response, the geometry of the detector array, and the reconstruction algorithm that was used determined the spatial resolution. We conclude that TACT imaging may have application to breast cancer detection.

  17. Application of DIRI dynamic infrared imaging in reconstructive surgery

    NASA Astrophysics Data System (ADS)

    Pawlowski, Marek; Wang, Chengpu; Jin, Feng; Salvitti, Matthew; Tenorio, Xavier

    2006-04-01

    We have developed the BioScanIR System based on QWIP (Quantum Well Infrared Photodetector). Data collected by this sensor are processed using the DIRI (Dynamic Infrared Imaging) algorithms. The combination of DIRI data processing methods with the unique characteristics of the QWIP sensor permit the creation of a new imaging modality capable of detecting minute changes in temperature at the surface of the tissue and organs associated with blood perfusion due to certain diseases such as cancer, vascular disease and diabetes. The BioScanIR System has been successfully applied in reconstructive surgery to localize donor flap feeding vessels (perforators) during the pre-surgical planning stage. The device is also used in post-surgical monitoring of skin flap perfusion. Since the BioScanIR is mobile; it can be moved to the bedside for such monitoring. In comparison to other modalities, the BioScanIR can localize perforators in a single, 20 seconds scan with definitive results available in minutes. The algorithms used include (FFT) Fast Fourier Transformation, motion artifact correction, spectral analysis and thermal image scaling. The BioScanIR is completely non-invasive and non-toxic, requires no exogenous contrast agents and is free of ionizing radiation. In addition to reconstructive surgery applications, the BioScanIR has shown promise as a useful functional imaging modality in neurosurgery, drug discovery in pre-clinical animal models, wound healing and peripheral vascular disease management.

  18. Prewarping techniques in imaging: applications in nanotechnology and biotechnology

    NASA Astrophysics Data System (ADS)

    Poonawala, Amyn; Milanfar, Peyman

    2005-03-01

    In all imaging systems, the underlying process introduces undesirable distortions that cause the output signal to be a warped version of the input. When the input to such systems can be controlled, pre-warping techniques can be employed which consist of systematically modifying the input such that it cancels out (or compensates for) the process losses. In this paper, we focus on the mask (reticle) design problem for 'optical micro-lithography', a process similar to photographic printing used for transferring binary circuit patterns onto silicon wafers. We use a pixel-based mask representation and model the above process as a cascade of convolution (aerial image formation) and thresholding (high-contrast recording) operations. The pre-distorted mask is obtained by minimizing the norm of the difference between the 'desired' output image and the 'reproduced' output image. We employ the regularization framework to ensure that the resulting masks are close-to-binary as well as simple and easy to fabricate. Finally, we provide insight into two additional applications of pre-warping techniques. First is 'e-beam lithography', used for fabricating nano-scale structures, and second is 'electronic visual prosthesis' which aims at providing limited vision to the blind by using a prosthetic retinally implanted chip capable of electrically stimulating the retinal neuron cells.

  19. High Throughput Multispectral Image Processing with Applications in Food Science.

    PubMed

    Tsakanikas, Panagiotis; Pavlidis, Dimitris; Nychas, George-John

    2015-01-01

    Recently, machine vision is gaining attention in food science as well as in food industry concerning food quality assessment and monitoring. Into the framework of implementation of Process Analytical Technology (PAT) in the food industry, image processing can be used not only in estimation and even prediction of food quality but also in detection of adulteration. Towards these applications on food science, we present here a novel methodology for automated image analysis of several kinds of food products e.g. meat, vanilla crème and table olives, so as to increase objectivity, data reproducibility, low cost information extraction and faster quality assessment, without human intervention. Image processing's outcome will be propagated to the downstream analysis. The developed multispectral image processing method is based on unsupervised machine learning approach (Gaussian Mixture Models) and a novel unsupervised scheme of spectral band selection for segmentation process optimization. Through the evaluation we prove its efficiency and robustness against the currently available semi-manual software, showing that the developed method is a high throughput approach appropriate for massive data extraction from food samples. PMID:26466349

  20. High Throughput Multispectral Image Processing with Applications in Food Science.

    PubMed

    Tsakanikas, Panagiotis; Pavlidis, Dimitris; Nychas, George-John

    2015-01-01

    Recently, machine vision is gaining attention in food science as well as in food industry concerning food quality assessment and monitoring. Into the framework of implementation of Process Analytical Technology (PAT) in the food industry, image processing can be used not only in estimation and even prediction of food quality but also in detection of adulteration. Towards these applications on food science, we present here a novel methodology for automated image analysis of several kinds of food products e.g. meat, vanilla crème and table olives, so as to increase objectivity, data reproducibility, low cost information extraction and faster quality assessment, without human intervention. Image processing's outcome will be propagated to the downstream analysis. The developed multispectral image processing method is based on unsupervised machine learning approach (Gaussian Mixture Models) and a novel unsupervised scheme of spectral band selection for segmentation process optimization. Through the evaluation we prove its efficiency and robustness against the currently available semi-manual software, showing that the developed method is a high throughput approach appropriate for massive data extraction from food samples.