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Sample records for intermediate qatari school

  1. Factors that Impact Student Usage of the Learning Management System in Qatari Schools

    ERIC Educational Resources Information Center

    Nasser, Ramzi; Cherif, Maha; Romanowski, Michael

    2011-01-01

    In an attempt to enhance teacher and student performance in school, a learning management system (LMS) known as Knowledge-Net (K-Net) was introduced in Qatari independent schools. (All public schools in Qatar have transformed to independent schools; the independent schools model is similar to the charter school system in North America.) An LMS is…

  2. Technology Integration in EFL Classrooms: A Study of Qatari Independent Schools

    ERIC Educational Resources Information Center

    Chaaban, Youmen; Ellili-Cherif, Maha

    2017-01-01

    The purpose of this study was to examine the impact of teachers' individual characteristics and perceptions of environmental factors on the extent of technology integration into EFL (English as a Foreign Language) classrooms. To this end, a national survey examining EFL teachers' perceptions was conducted at Qatari Independent Schools. A total of…

  3. Social motivation in Qatari schools and their relation to school achievement.

    PubMed

    Nasser, Ramzi

    2014-10-01

    This study assessed the relation between school-social motivation and student academic achievement. A factor analysis was performed on a set of school-social items selected a priori from three measures of school motivation: the Inventory of School Motivation, the General Achievement Goals Orientation Scale, and the Facilitating Conditions Scale. Three factors with fewer items represented Global Motivation, Peer Help, and Social Power. Hierarchical regression analysis showed social motivation measures were weak predictors of achievement scores in the various content areas. Findings are discussed in the context of Qatari education and culture.

  4. Achievement-Oriented Beliefs and Their Relation to Academic Expectations and School Achievement among Qatari Students

    ERIC Educational Resources Information Center

    Nasser, Ramzi; McInerney, Dennis

    2016-01-01

    This study investigated the relation between motivational goals and university intentions, school valuing and school achievement. The premise of this study is that motivational goals play a key role in academic values and achievement. Confirmatory factor analysis was conducted to establish the construct validity of the motivational measures drawn…

  5. Achievement-Oriented Beliefs and Their Relation to Academic Expectations and School Achievement among Qatari Students

    ERIC Educational Resources Information Center

    Nasser, Ramzi; McInerney, Dennis

    2016-01-01

    This study investigated the relation between motivational goals and university intentions, school valuing and school achievement. The premise of this study is that motivational goals play a key role in academic values and achievement. Confirmatory factor analysis was conducted to establish the construct validity of the motivational measures drawn…

  6. Dee-Mack Intermediate School

    ERIC Educational Resources Information Center

    Northwest Evaluation Association, 2012

    2012-01-01

    Frank Reliford, the Principal at Dee-Mack Intermediate since 2005, is familiar to almost every child in the community. 260 Students attend Reliford's school, and their status is a point of pride: Dee-Mack Intermediate is consistently one of the highest performing schools in the state. The change in student performance correlates to the…

  7. Teacher Education for the Intermediate School Staff.

    ERIC Educational Resources Information Center

    Stainbrook, James R., Jr.

    The aim of this 1970 investigation was to analyze the professional education of Indiana's intermediate school teachers. This analysis involved a comparison of the data collected from middle and junior high school teachers. Results obtained from the junior high school teachers were also utilized in a second comparison with the findings from a…

  8. Giano Intermediate School: The Parent Factor

    ERIC Educational Resources Information Center

    Rourke, James; Hartzman, Marlene

    2009-01-01

    On a Wednesday morning at Giano Intermediate School in West Covina, California, 25 mothers and fathers sit in rapt attention, many taking notes, as a school counselor outlines the morning's Parent Chat. The session is devoted to exploring how well the parents know their children. Parents complete a questionnaire that asks them to answer such…

  9. Giano Intermediate School: The Parent Factor

    ERIC Educational Resources Information Center

    Rourke, James; Hartzman, Marlene

    2009-01-01

    On a Wednesday morning at Giano Intermediate School in West Covina, California, 25 mothers and fathers sit in rapt attention, many taking notes, as a school counselor outlines the morning's Parent Chat. The session is devoted to exploring how well the parents know their children. Parents complete a questionnaire that asks them to answer such…

  10. Validation of the General Self-Efficacy Scale among Qatari young women.

    PubMed

    Crandall, A; Rahim, H F Abdul; Yount, K M

    2016-03-15

    The General Self-Efficacy Scale (GSES) is a measure of people's beliefs about their capacity to cope with life's demands. Self-efficacy may be particularly relevant in transitional stages such as in late adolescence, when young people make decisions that will impact their adult lives. In the present study, we aimed to validate an Arabic version of GSES among 355 Qatari young women aged 18+ years and finishing their final year of high school. We conducted exploratory and confirmatory factor analyses to assess the scale dimensionality. The final model fit was adequate (root mean square error of approximation = 0.07, comparative fit index = 1.00, Tucker-Lewis index = 0.99), confirming a unidimensional self-efficacy measure. The Qatari Standard Arabic GSES is a reliable tool for measuring general self-efficacy among young Qatari women.

  11. Renne Intermediate School Features Personalized Instruction.

    ERIC Educational Resources Information Center

    Profiles, Programs & Products, 1983

    1983-01-01

    Renne (Oregon) Intermediate School offers an innovative program of personalized instruction to students in grades 6-8. Teachers work closely with individual students, following a continuous progress curriculum which allows cross-grade-level placement in the core areas of math, reading, and language arts. Based on cooperative district planning, the…

  12. How Do Qataris Source Health Information?

    PubMed Central

    Choudhury, Sopna M.; Arora, Teresa; Alebbi, Seham; Ahmed, Lina; Aden, Abdi; Omar, Omar; Taheri, Shahrad

    2016-01-01

    Background Qatar is experiencing rapid population expansion with increasing demands on healthcare services for both acute and chronic conditions. Sourcing accurate information about health conditions is crucial, yet the methods used for sourcing health information in Qatar are currently unknown. Gaining a better understanding of the sources the Qatari population use to recognize and manage health and/or disease will help to develop strategies to educate individuals about existing and emerging health problems. Objective To investigate the methods used by the Qatari population to source health information. We hypothesized that the Internet would be a key service used to access health information by the Qatari population. Methods A researcher-led questionnaire was used to collect information from Qatari adults, aged 18–85 years. Participants were approached in shopping centers and public places in Doha, the capital city of Qatar. The questionnaire was used to ascertain information concerning demographics, health status, and utilization of health care services during the past year as well as sources of health information used. Results Data from a total of 394 eligible participants were included. The Internet was widely used for seeking health information among the Qatari population (71.1%). A greater proportion of Qatari females (78.7%) reported searching for health-related information using the Internet compared to Qatari males (60.8%). Other commonly used sources were family and friends (37.8%) and Primary Health Care Centers (31.2%). Google was the most commonly used search engine (94.8%). Gender, age and education levels were all significant predictors of Internet use for heath information (P<0.001 for all predictors). Females were 2.9 times more likely than males (P<0.001) and people educated to university or college level were 3.03 times more likely (P<0.001) to use the Internet for heath information. Conclusions The Internet is a widely used source to obtain

  13. What Motivates and Engages Students in the Education Process--An Examination of Qatari Students' Mindset and Attitudes toward Going to School, Learning, and Future Aspirations

    ERIC Educational Resources Information Center

    Lee, Seungah

    2016-01-01

    This paper examines student attitudes towards school and learning among students in Qatar's public schools. Drawing upon student surveys administered to 1091 grade 7 and 8 students in 11 independent preparatory schools, the paper observes patterns of attitudes and behavior towards learning, school, and future aspirations. Findings show that…

  14. The Molecular Basis of α-Thalassemia in the Qatari Pediatric Population.

    PubMed

    Kamal, Madeeha; Abu-Sirriya, Shaza; Abu-Dayya, Aseel; Al-Khatib, Hebah; Abu-Ramadan, Hadeel; Petrou, Miranda; Amer, Aliaa; Badii, Ramin; Kleanthous, Marina

    2015-01-01

    α-Thalassemia (α-thal) is widely reported in the Arabian Peninsula as one of the main causes of asymptomatic microcytic hypochromic red blood cells with or without anemia in the pediatric population. This is the first study that provides information about the molecular basis of α-thal in the Qatari population. Qatari school children between the ages of 5 and 15, exhibiting laboratory findings suggestive of microcytic anemia were pooled, and those with a mean corpuscular volume (MCV) of <80.0 fL and a hemoglobin (Hb) electropherogram that ruled out β-thalassemia (β-thal), were narrowed down to a group of 127. This group was screened for the -α(3.7) (rightward) deletion, and the α(-5 nt), α(polyA1) (α(T-Saudi)), α(polyA2) mutations. A second group of randomly selected Qatari individuals was also screened in order to determine the population's allele frequency for the -α(3.7) deletion. Thirty-nine point four percent of the individuals with microcytic hypochromic anemia were positive for the -α(3.7) deletion (heterozygotes 30.0%, homozygotes 9.4%), 2.6% were positive for the α(polyA1) deletion and 0.8% positive for the α(-5 nt) mutation. None of the children exhibited changes in α(polyA2). Analysis of the random samples determined that 26.4% were heterozygous and 4.5% homozygous for the -α(3.7) deletion with a 17.7% allele frequency. Our results suggest that a significant number of the Qatari pediatric population with microcytic hypochromic anemia are carriers of α-thal mutations. However, 45.6% of the children failed to exhibit any of the above four mutations tested. This suggests the possibility of other mutations in the Qatari pediatric population that are yet to be elicited.

  15. The Intermediate School Principal: An In-Basket Simulation Exercise.

    ERIC Educational Resources Information Center

    Musella, Donald F.; Joyce, H. Donald

    The materials in this booklet simulate some of the problems that intermediate (junior high, middle, and senior elementary) school principals could face under actual working conditions. Taken from the real-life problems of some intermediate school principals, the exercises are presented in the form of in-basket items -- letters, memos, phone…

  16. Kent Intermediate School District: From Invisible Agency to Power Player

    ERIC Educational Resources Information Center

    Koehler, Ronald

    2009-01-01

    Michigan's intermediate school districts were created by constitutional convention in 1962. Between their inception and 2000, few units of government were less visible and less understood. This article chronicles the emergence of one intermediate school district as an aggressive force for change in education and a locus of activity for community…

  17. Exemplary Dissemination Programs for Intermediate Units Serving Rural Schools.

    ERIC Educational Resources Information Center

    Edington, Everett; Hays, Leonard

    Utilizing information derived from documents, site visits, correspondence, and personal interviews re: 6 intermediate education units serving rural schools which were initially identified via a mail survey, this report describes intermediate education units with exemplary information dissemination programs. Varying considerably, each program is…

  18. Causal explanations of miscarriage amongst Qataris.

    PubMed

    Kilshaw, Susie; Omar, Nadia; Major, Stella; Mohsen, Mona; El Taher, Faten; Al Tamimi, Halima; Sole, Kristina; Miller, Daniel

    2017-07-27

    Despite its commonality, there is a paucity of literature on miscarriage in non-Western societies. In particular, there is little understanding of how people ascribe cause to miscarriage. This research sought to gain an in-depth understanding of notions of miscarriage causality and risk amongst Qataris. The study adopted an exploratory descriptive qualitative approach and collected data during 18 months of ethnographic research in Qatar, including semi-structured interviews. The sample includes 60 primary participants (20 pregnant women and 40 women who had recently miscarried), and 55 secondary participants including family members, health care providers, religious scholars and traditional healers. Informed consent was obtained from all participants. Primary participants were interviewed in Arabic. The interviews were audio recorded, transcribed and translated into English. Data was analysed using an inductive thematic approach, which involved identification and application of multiple codes to different text segments. Data were encoded manually and examined for recurrences across the data set. Similar quotations were grouped into subcategories and further categorized into main themes. A number of key themes emerged, revealing Qatari women attributed miscarriages to a number of factors including: supernatural forces, such as God's will and evil eye; lifestyle, such as physical activities and consuming particular substances; medical conditions, such as diabetes; and emotional state, such as stress, and emotional upset. Resting, avoiding stress and upset, maintaining healthy diet, and spiritual healing (ruqyah) are seen as a means to avoid miscarriage. Practices and beliefs around miscarriage are embedded in social, cultural, religious and medical frameworks. Understanding the socio-cultural context and understandings of explanatory theories can enhance health care providers' understandings, resulting in improved communication and care.

  19. Bullying during the Intermediate School Phase: A South African Study

    ERIC Educational Resources Information Center

    Greeff, P.; Grobler, A. A.

    2008-01-01

    Bullying in the intermediate school phase was studied, using the Revised Olweus Bully/Victim Questionnaire (R-OBVQ). The total sample comprised 360 grade 4 to 6 pupils from English-medium, single-sex schools in Bloemfontein, South Africa. To ensure a more homogeneous sample, the grade (grades 4 to 6) and race (black and white) of the participants…

  20. Cyberbullying in a Rural Intermediate School: An Exploratory Study

    ERIC Educational Resources Information Center

    Bauman, Sheri

    2010-01-01

    Students (N = 221) in an intermediate school (grades 5-8) in a rural area of the Southwestern United States completed a survey regarding their familiarity with technology and their experiences with cyberbullying during the school year. Initial evidence of survey reliability is presented. In the sample, 1.5% of participants were classified as…

  1. Vertical Integration at Junior and Intermediate Levels. School Research Newsletter.

    ERIC Educational Resources Information Center

    Marklund, Inger, Ed.; Hanse, Mona-Britt, Ed.

    1984-01-01

    In recent years, there has been a rapid growth of interest in Sweden in vertically integrated classes in compulsory schools, especially at junior high school and intermediate grade levels. This development is supported in various ways by the curriculum, partly because it puts more emphasis than previous curricula on the occurrence of teaching…

  2. Type 2 Diabetes Risk Allele Loci in the Qatari Population

    PubMed Central

    Abi Khalil, Charbel; Fakhro, Khalid A.; Robay, Amal; Ramstetter, Monica D.; Al-Azwani, Iman K.; Malek, Joel A.; Zirie, Mahmoud; Jayyousi, Amin; Badii, Ramin; Al-Nabet Al-Marri, Ajayeb; Chiuchiolo, Maria J.; Al-Shakaki, Alya; Chidiac, Omar; Gharbiah, Maey; Bener, Abdulbari; Stadler, Dora; Hackett, Neil R.; Mezey, Jason G.; Crystal, Ronald G.

    2016-01-01

    Background The prevalence of type 2 diabetes (T2D) is increasing in the Middle East. However, the genetic risk factors for T2D in the Middle Eastern populations are not known, as the majority of studies of genetic risk for T2D are in Europeans and Asians. Methods All subjects were ≥3 generation Qataris. Cases with T2D (n = 1,124) and controls (n = 590) were randomly recruited and assigned to the 3 known Qatari genetic subpopulations [Bedouin (Q1), Persian/South Asian (Q2) and African (Q3)]. Subjects underwent genotyping for 37 single nucleotide polymorphisms (SNPs) in 29 genes known to be associated with T2D in Europeans and/or Asian populations, and an additional 27 tag SNPs related to these susceptibility loci. Pre-study power analysis suggested that with the known incidence of T2D in adult Qataris (22%), the study population size would be sufficient to detect significant differences if the SNPs were risk factors among Qataris, assuming that the odds ratio (OR) for T2D SNPs in Qatari’s is greater than or equal to the SNP with highest known OR in other populations. Results Haplotype analysis demonstrated that Qatari haplotypes in the region of known T2D risk alleles in Q1 and Q2 genetic subpopulations were similar to European haplotypes. After Benjamini-Hochberg adjustment for multiple testing, only two SNPs (rs7903146 and rs4506565), both associated with transcription factor 7-like 2 (TCF7L2), achieved statistical significance in the whole study population. When T2D subjects and control subjects were assigned to the known 3 Qatari subpopulations, and analyzed individually and with the Q1 and Q2 genetic subpopulations combined, one of these SNPs (rs4506565) was also significant in the admixed group. No other SNPs associated with T2D in all Qataris or individual genetic subpopulations. Conclusions With the caveats of the power analysis, the European/Asian T2D SNPs do not contribute significantly to the high prevalence of T2D in the Qatari population, suggesting

  3. Microbial Characterization of Qatari Barchan Sand Dunes.

    PubMed

    Abdul Majid, Sara; Graw, Michael F; Chatziefthimiou, Aspassia D; Nguyen, Hanh; Richer, Renee; Louge, Michel; Sultan, Ali A; Schloss, Patrick; Hay, Anthony G

    This study represents the first characterization of sand microbiota in migrating barchan sand dunes. Bacterial communities were studied through direct counts and cultivation, as well as 16S rRNA gene and metagenomic sequence analysis to gain an understanding of microbial abundance, diversity, and potential metabolic capabilities. Direct on-grain cell counts gave an average of 5.3 ± 0.4 x 105 cells g-1 of sand. Cultured isolates (N = 64) selected for 16S rRNA gene sequencing belonged to the phyla Actinobacteria (58%), Firmicutes (27%) and Proteobacteria (15%). Deep-sequencing of 16S rRNA gene amplicons from 18 dunes demonstrated a high relative abundance of Proteobacteria, particularly enteric bacteria, and a dune-specific-pattern of bacterial community composition that correlated with dune size. Shotgun metagenome sequences of two representative dunes were analyzed and found to have similar relative bacterial abundance, though the relative abundances of eukaryotic, viral and enterobacterial sequences were greater in sand from the dune closer to a camel-pen. Functional analysis revealed patterns similar to those observed in desert soils; however, the increased relative abundance of genes encoding sporulation and dormancy are consistent with the dune microbiome being well-adapted to the exceptionally hyper-arid Qatari desert.

  4. Microbial Characterization of Qatari Barchan Sand Dunes

    PubMed Central

    Chatziefthimiou, Aspassia D.; Nguyen, Hanh; Richer, Renee; Louge, Michel; Sultan, Ali A.; Schloss, Patrick; Hay, Anthony G.

    2016-01-01

    This study represents the first characterization of sand microbiota in migrating barchan sand dunes. Bacterial communities were studied through direct counts and cultivation, as well as 16S rRNA gene and metagenomic sequence analysis to gain an understanding of microbial abundance, diversity, and potential metabolic capabilities. Direct on-grain cell counts gave an average of 5.3 ± 0.4 x 105 cells g-1 of sand. Cultured isolates (N = 64) selected for 16S rRNA gene sequencing belonged to the phyla Actinobacteria (58%), Firmicutes (27%) and Proteobacteria (15%). Deep-sequencing of 16S rRNA gene amplicons from 18 dunes demonstrated a high relative abundance of Proteobacteria, particularly enteric bacteria, and a dune-specific-pattern of bacterial community composition that correlated with dune size. Shotgun metagenome sequences of two representative dunes were analyzed and found to have similar relative bacterial abundance, though the relative abundances of eukaryotic, viral and enterobacterial sequences were greater in sand from the dune closer to a camel-pen. Functional analysis revealed patterns similar to those observed in desert soils; however, the increased relative abundance of genes encoding sporulation and dormancy are consistent with the dune microbiome being well-adapted to the exceptionally hyper-arid Qatari desert. PMID:27655399

  5. The Development and Implementation of an Articulation Model Between the Intermediate School and Feeder Elementary Schools.

    ERIC Educational Resources Information Center

    Kilpatrick, John W.

    This practicum developed a model of vertical articulation between elementary feeder schools and an intermediate school. The program and model were developed after a formal needs assessment was carried out to determine articulation problems. After problems were determined, objectives were formulated and strategies developed. Objectives that…

  6. Fossil Ridge School Intermediate: Restructure the Culture--Transform the School

    ERIC Educational Resources Information Center

    Principal Leadership, 2013

    2013-01-01

    Ask a room full of sixth and seventh graders at Fossil Ridge Intermediate School in St. George, UT, to name their favorite part of the day and the answer is, in unison, always the same: REAL (respect, explore, achieve, lead) Time. This 35-minute block embedded into the school's schedule three days each week provides immediate, specific…

  7. Fossil Ridge School Intermediate: Restructure the Culture--Transform the School

    ERIC Educational Resources Information Center

    Principal Leadership, 2013

    2013-01-01

    Ask a room full of sixth and seventh graders at Fossil Ridge Intermediate School in St. George, UT, to name their favorite part of the day and the answer is, in unison, always the same: REAL (respect, explore, achieve, lead) Time. This 35-minute block embedded into the school's schedule three days each week provides immediate, specific…

  8. Physical Education Policies and Practices in Qatari Preschools: A Cross-Cultural Study

    ERIC Educational Resources Information Center

    Al-Thani, Tamader; Semmar, Yassir

    2016-01-01

    Anecdotal evidence and empirical research point out to the low physical activity levels at preschools as well as the global rise in childhood obesity rates. Placing a high premium on sports and healthy well-being of its citizens by the Qatari government, taking into account the increasing prevalence of overweight and obesity among Qatari children,…

  9. Pattern of benign ovarian cysts in Qatari women

    PubMed Central

    Zahra, Fatimah

    2016-01-01

    Objective: To study the age distribution, histopathological types, lateral distribution and surgical interventions performed for benign ovarian cysts in Qatari women undergoing surgical intervention for an ovarian cyst. Design: A retrospective descriptive study. Setting: Obstetrics and Gynecology Department, Al-Ahli Hospital, Doha, Qatar. Patients and methods: Data were collected retrospectively from clinical records of Qatari women who underwent surgical intervention from 1 January 2013 to 31 December 2015 at Al-Ahli Hospital for an ovarian or paraovarian cyst. The age distribution, frequencies and percentages were calculated for each type of ovarian cyst and the side of the ovary involved was recorded. Results were statistically analysed by IBM SPSS, version 23. Results: A total of 81 women had an ovarian or paraovarian cyst. Age ranged from 16 to 58 years. The maximum number of women were in the 21–30-year-old age group. Benign epithelial cysts were found to be most common (32; 39.5%), of which the majority were for endometriotic cysts (15; 18.5%), serous cystadenoma (13; 16%) and mucinous cystadenoma (4; 4.9%). This was followed by physiological cysts (26; 32.1%), which included corpus luteal cysts (15; 18.5%) and simple follicular cysts (11; 13.6%). The other categories of ovarian tumours were for mature cystic teratoma (14; 17.3%), benign sex cord–stromal tumours (1; 1.2%) which included stromal cell tumours (1; 1.2%), borderline ovarian tumour (1; 1.2%) and paraovarian cysts (7; 8.6%). There was bilateral ovarian involvement in 9 cases (11.1%) and unilateral involvement in 72 (88.9%). The right ovary was involved in more cases (39; 48.1%), than for the left ovary (33; 40.7%). Conclusion: Benign epithelial tumours were found to be the most common type of ovarian tumour in Qatari women. Endometriotic cysts followed by serous cystadenomas were the most common types of benign epithelial tumours. The right ovary was found to be involved in more cases than the

  10. Findings from the 2013 NZCER Primary and Intermediate Schools National Survey

    ERIC Educational Resources Information Center

    New Zealand Council for Educational Research, 2014

    2014-01-01

    The New Zealand Council for Educational Research (NZCER) primary and intermediate schools national survey was carried out in July-August 2013. NZCER questioned principals, teachers and trustees at a representative sample of schools, and sought the views of a random sample of 1 in 4 parents in 36 of these schools. In all, the survey gathered data…

  11. Native American Curriculum: Primary, Intermediate, Junior High, High School.

    ERIC Educational Resources Information Center

    Fox, Sandra J.

    These four books provide curricular materials for the study of North Dakota Indians at primary through high school levels. Issued on the occasion of the North Dakota centennial, they provide information about Indians that can be integrated into the school curriculum. The books at all levels begin with study of the centennial logo, pictured on the…

  12. Native American Curriculum: Primary, Intermediate, Junior High, High School.

    ERIC Educational Resources Information Center

    Fox, Sandra J.

    These four books provide curricular materials for the study of North Dakota Indians at primary through high school levels. Issued on the occasion of the North Dakota centennial, they provide information about Indians that can be integrated into the school curriculum. The books at all levels begin with study of the centennial logo, pictured on the…

  13. Van Buren Intermediate School District. Common Threads for the Future. Michigan Exemplary Career Guidance Programs.

    ERIC Educational Resources Information Center

    Van Buren Intermediate School District, Lawrence, MI.

    The Van Buren Intermediate School District in Michigan has developed a comprehensive guidance program that has been adopted by a number of school districts in the state. The Van Buren model is designed to teach all youth and adults the career development skills of information gathering, decision making, planning, and placement. This document…

  14. Are New Zealand schools smoke-free? Results from a national survey of primary and intermediate school principals.

    PubMed

    Reeder, A; Glasgow, H

    2000-02-25

    To document policies and practices developed by primary and intermediate schools in response to the Smoke-free Environments Act 1990 and estimate levels of staff support for legislation requiring totally smoke-free schools. Questionnaires were mailed to a random national sample of 10% of principals of all primary and intermediate schools. There were 209 questionnaires returned, a response rate of 87%. While 97% of principals reported that their school had a written policy for smoking, only 58% provided a copy. Only 49% of principals said that their school smoking policy was prominently displayed. Most (82 %) claimed that school buildings were smoke-free, but only 44% said that this applied to buildings and grounds. Overall, 62% considered that school staff would support legislation that required schools to be totally smoke-free in buildings and grounds. School policies ranged from total prohibition of smoking in school buildings and grounds to the provision of designated smoking areas for staff. Compliance with current smoke-free legislation appears to be variable. Consistency in the meaning of smoke-free status in schools is lacking. There appears to be good staff and parent support for making all schools totally smoke-free. The best way to achieve universal, permanent and totally smoke-free status for New Zealand schools would be to amend current legislation to include specific requirements for all school premises.

  15. Manual for Interpreting Intermediate School Reports, Grade 9.

    ERIC Educational Resources Information Center

    Burson, William W.

    This manual is designed to aid the school administrator and staff in the interpretation of Pennsylvania's Educational Quality Assessment Report for Grade Nine. General background information is presented on the ten goals of quality education which were assessed. These goals include: self esteem; understanding others; basic verbal and math skills;…

  16. The prevalence and distribution of nonsyndromic hyperdontia in a group of Qatari orthodontic and pediatric patients

    PubMed Central

    Alhashimi, Najah; Abed Al Jawad, Feras H.; Al Sheeb, Muneera; Al Emadi, Buthaina; Al-Abdulla, Jamal; Al Yafei, Hanan

    2016-01-01

    Objective: There is no data specific to the Qatari population on the prevalence and distribution of hyperdontia. The aim of this study was to investigate the prevalence and distribution of hyperdontia in the permanent teeth among a group of Qatari sample and to compare the present results with findings from other populations. Materials and Methods: Records of 1269 Qatari patients (674 females; mean age 11.8 ± 2.3 and 595 males; mean age 11.4 ± 2.2 years) which included panoramic radiographs were examined to identify hyperdontia in the permanent dentition. Supernumerary teeth were assessed for their location, morphology, number, and whether impacted or not. Results: The prevalence of hyperdontia was 1.6% (females 0.7% and males 0.9%; P < 0169). The most common type of supernumerary teeth was the supplemental (45.5%), followed by the conical (40%). Of the supplemental teeth, the mandibular incisor was the most prevalent (60%), followed by the premolar (20%). No significant difference in the prevalence was found between the maxilla and mandible. More than half of supernumerary teeth identified were impacted (54.5%). Conclusions: The prevalence of hyperdontia in a group of Qatari population was within the normal range of the majority of published studies in the literature. Although not significant, hyperdontia cases were more prevalent in male patients. PMID:27403060

  17. Orsomucoid: A new variant and additional duplicated ORM1 gene in Qatari population

    SciTech Connect

    Sebetan, I.M.; Alali, K.A.; Alzaman, A.

    1994-09-01

    A new genetically determined ORM2 variant and additional duplicated ORM1 gene were observed in Qatari population using isoelectric focusing in ultra thin layer polyacrylamide gels. The studied population samples indicate occurence of six ORM1 alleles and three ORM2 ones. A simple reliable method for separation of orsomucoid variations with comparison of different reported methods will be presented.

  18. Qatari Women in a Corporatized Higher Education Setting: International Reforms and Their Local Bearings

    ERIC Educational Resources Information Center

    Al-Muftah, Esraa

    2017-01-01

    Discussions of the difficulties Qatari women experience in higher educational settings are unlikely to be found in international organization or government reports on the State of Qatar. Instead, recent reports have tended to gloss over gender inequalities raising a "successful girl discourse." Drawing on my own teaching experience at…

  19. Raising Reading Achievement in an "At Risk", Low Socioeconomic, Multicultural Intermediate School

    ERIC Educational Resources Information Center

    Fletcher, Jo; Grimley, Michael; Greenwood, Janinka; Parkhill, Faye

    2013-01-01

    This article focuses on a multicultural, low socioeconomic, intermediate school that over the 4 years of this longitudinal, qualitative, case study made substantial positive shifts in developing a more effective learning environment and improving students' reading achievement. The study found that the factors appearing to have the most influence…

  20. Low Income African Americans' Parental Involvement in Intermediate Schools: Perceptions, Practices, and Influences

    ERIC Educational Resources Information Center

    Petty, Benjamin

    2012-01-01

    Purpose: The purpose of this study was to examine how the parental involvement perceptions, practices, and influences of low-income African Americans in an intermediate school setting are affected by low-incomes. Although involving African American parents in the educational process is a difficult task for educators (Alldred & Edwards, 2000;…

  1. A Curriculum Guide for Primary and Intermediate Special Education in the Opelika City Schools. Revised Edition.

    ERIC Educational Resources Information Center

    Opelika City Schools, AL.

    Presented is a curriculum guide for primary and intermediate special education in the areas of communication skills, arithmetic, science, and physical education. The guide, prepared by the Opelika (Alabama) schools, is said to be based on assumptions such as the values of structured individualized learning, use of materials which do not require…

  2. Low Income African Americans' Parental Involvement in Intermediate Schools: Perceptions, Practices, and Influences

    ERIC Educational Resources Information Center

    Petty, Benjamin

    2012-01-01

    Purpose: The purpose of this study was to examine how the parental involvement perceptions, practices, and influences of low-income African Americans in an intermediate school setting are affected by low-incomes. Although involving African American parents in the educational process is a difficult task for educators (Alldred & Edwards, 2000;…

  3. The prevalence and metabolic characteristics of polycystic ovary syndrome in the Qatari population.

    PubMed

    Dargham, Soha R; Ahmed, Lina; Kilpatrick, Eric S; Atkin, Stephen L

    2017-01-01

    The prevalence of polycystic ovary syndrome (PCOS) in the Qatari population is unknown and hence the estimated impact on the local population cannot be determined. The purpose of this study was to estimate the prevalence and metabolic features of PCOS among Qatari women. Cross sectional analysis. 3,017 Qatari subjects volunteered to be phenotyped and genotyped for the Qatar Biobank from which all women between the ages of 18-40 years were identified (750). 720 women had testosterone and sex hormone binding globulin (SHBG) measurements. PCOS was diagnosed according the National Institute of Health (NIH) Guidelines of a raised androgen level (free androgen index >4.5 or a raised total testosterone) and menstrual irregularity after the exclusion of other conditions. All results are reported as mean value of PCOS versus control. 87 of 720 women fulfilled the NIH guidelines (12.1%) for PCOS specifically using a free androgen index greater than 4.5 or a total testosterone greater than 2.7nmol/l and menstrual irregularity. Subjects were heavier with a more metabolic profile of a greater systolic and diastolic blood pressure, higher levels of C reactive protein, insulin (p<0.01) and HbA1c (P<0.02), and decreased HDL levels (p<0.01). Pulse wave velocity as a marker of arterial stiffness was also increased (p<0.05). By NIH guidelines the prevalence of PCOS in this Qatari cohort was 12.1% that would likely reflect 20% by Rotterdam criteria, with a markedly more metabolic phenotype than Qatari controls.

  4. Bolton tooth size ratio among qatari population sample: An odontometric study

    PubMed Central

    Hashim, Hayder A; AL-Sayed, Najah; AL-Hussain, Hashim

    2017-01-01

    Objectives: To establish the overall and anterior Bolton ratio among a sample of Qatari population and to investigate whether there is a difference between males and females, as well as to compare the result obtained by Bolton. Materials and Methods: The current study consisted of 100 orthodontic study participants (50 males and 50 females) with different malocclusions and age ranging between 15 and 20 years. An electronic digital caliper was used to measure the mesiodistal tooth width of all maxillary and mandibular permanent teeth except second and third molars. The Student's t-test was used to compare tooth-size ratios between males and females and between the results of the present study and Bolton's result. Results: The anterior and overall ratio in Qatari individuals were 78.6 ± 3.4 and 91.8 ± 3.1, respectively. The tooth size ratios were slightly greater in males than that in females, however, the differences were not statistically significant (P > 0.05). There were no significant differences in the overall ratio between Qatari individuals and Bolton's results (P > 0.05), whereas statistical significant differences were observed in anterior ratio (P = 0.007). Conclusions: Within the limitation of the limitations of the present study, definite conclusion was difficult to establish. Thus, a further study with a large sample in each malocclusion group is required. PMID:28197399

  5. The prevalence and distribution of hypodontia in a sample of Qatari patients

    PubMed Central

    Hashim, Hayder Abdalla; Al-Said, Sozan

    2016-01-01

    Objective: The aims of this study were to determine the prevalence of hypodontia in the permanent dentition in a sample of Qatari patients attending a dental center and to compare the results with the reported findings of other populations. Materials and Methods: Orthodontic files including orthopantomographs of 1000 patients (655 females and 345 males, 11–36-year-old) were examined and inspected for evidence of hypodontia. Results: The prevalence of hypodontia in the present Qatari sample was 7.8%; 6.9% was in males and 8.2% in females. Hypodontia was found more frequently in the maxilla than in the mandible. The distribution of missing teeth was noticed in the left side more than the right side. The most frequently missing teeth were the maxillary lateral incisors followed by the mandibular second premolars, maxillary second premolars, and mandibular left lateral incisor. The majority of patients with hypodontia had one or two teeth missing, but rarely more than four teeth were missing in the same patient. Bilateral missing teeth in the current study was commonly seen in the maxillary lateral incisor (14.1%) followed by mandibular second premolar (12.8%) and maxillary second premolar (6.4%). Conclusions: The prevalence of hypodontia in a sample of Qatari individuals was within the range reported in the literature for other populations. The incidence of hypodontia in the anterior segment requires multidisciplinary team approach (orthodontic and prosthodontic) to restore the esthetic and function and improve patient self-esteem. PMID:26998470

  6. Limited English Proficient Students in Intermediate Schools and in High Schools.A Concern About...

    ERIC Educational Resources Information Center

    Concerns, 1993

    1993-01-01

    The typical public school classroom is more diverse, linguistically and ethnically, than 20 years ago, with a dramatic increase in the proportion of limited-English-proficient (LEP) students. This pattern is reflected in secondary as well as elementary schools. Research indicates many of these students are at risk of failure or dropping out. A…

  7. Improving Finance for Qatari Education Reform. Research Brief

    ERIC Educational Resources Information Center

    Guarino, Cassandra M.; Galama, Titus; Constant, Louay; Gonzalez, Gabriella; Tanner, Jeffery C.; Goldman, Charles A.

    2009-01-01

    Qatar's education reform, which included implementation of a new finance system, appears to be providing schools with adequate funding but is still struggling with issues of transparency and swift policy shifts that have been difficult to accommodate. [For full report, "Developing a School Finance System for K-12 Reform in Qatar", see…

  8. Improving Finance for Qatari Education Reform. Research Brief

    ERIC Educational Resources Information Center

    Guarino, Cassandra M.; Galama, Titus; Constant, Louay; Gonzalez, Gabriella; Tanner, Jeffery C.; Goldman, Charles A.

    2009-01-01

    Qatar's education reform, which included implementation of a new finance system, appears to be providing schools with adequate funding but is still struggling with issues of transparency and swift policy shifts that have been difficult to accommodate. [For full report, "Developing a School Finance System for K-12 Reform in Qatar", see…

  9. Formative, Process, and Intermediate Outcome Evaluation of a Pilot School-based 5 A Day for Better Health Project.

    ERIC Educational Resources Information Center

    Harris, Kari Jo; Richter, Kimber P.; Schultz, Jerry; Johnston, Judy

    1998-01-01

    Examines formative, process, and intermediate outcome results of a school-based project linked to the National 5 A Day for Better Health campaign to increase fruit and vegetable consumption. Three elementary schools conducted the local campaign. Activity logs, redeemed coupons, and focus groups indicated that the project was implemented as planned…

  10. First premarital screening of thalassaemia carriers in intermediate schools in Latium.

    PubMed

    Silvestroni, E; Bianco, I; Graziani, B; Carboni, C; D'Arca, S U

    1978-06-01

    In the 1975 to 1976 school year, under the auspices of the Health Authorities of the Latium Region, the Rome Microcythaemia Centre carried out for the first time a partial screening survey of thalassaemia carriers among the students of the compulsory intermediate school in Latium. This work was the beginning of a new preventive school health service aimed at the prophylaxis of Cooley's disease. In 23 places investigated in Latium, 17724 students were examined, 13354 of whom were in Rome and 4370 elsewhere. The mean percentage of co-operation was 70% and the mean percentage of thalassaemia 2.42%. Thalassaemic students were invited to attend the centre for a check-up along with their families: about half had already come in by the end of June 1976. All students examined, whether normal or thalassaemic, have received written results of the tests. The screening survey aroused notable interest and obtained wide approval both at school and at home. The news of being thalassaemia carriers, even if not welcome, was never the cause of family tragedy.

  11. First premarital screening of thalassaemia carriers in intermediate schools in Latium.

    PubMed Central

    Silvestroni, E; Bianco, I; Graziani, B; Carboni, C; D'Arca, S U

    1978-01-01

    In the 1975 to 1976 school year, under the auspices of the Health Authorities of the Latium Region, the Rome Microcythaemia Centre carried out for the first time a partial screening survey of thalassaemia carriers among the students of the compulsory intermediate school in Latium. This work was the beginning of a new preventive school health service aimed at the prophylaxis of Cooley's disease. In 23 places investigated in Latium, 17724 students were examined, 13354 of whom were in Rome and 4370 elsewhere. The mean percentage of co-operation was 70% and the mean percentage of thalassaemia 2.42%. Thalassaemic students were invited to attend the centre for a check-up along with their families: about half had already come in by the end of June 1976. All students examined, whether normal or thalassaemic, have received written results of the tests. The screening survey aroused notable interest and obtained wide approval both at school and at home. The news of being thalassaemia carriers, even if not welcome, was never the cause of family tragedy. PMID:671484

  12. Spanish Books for Elementary, Intermediate and Advanced Studies: Elementary Schools, High Schools, Colleges, Libraries.

    ERIC Educational Resources Information Center

    1967

    An enumerated, selected, 2,480-item bibliography of publications and records on Spanish culture and literature with prices is offered primarily for school and library use. Subject entry in this work is alphabetical in each of the major divisions. Broadly grouped classifications include: (1) fiction, (2) essays, (3) individual author collections,…

  13. Screening of thalassaemia carriers in intermediate school of Latium: results of four years' work.

    PubMed

    Silvestroni, E; Bianco, I; Graziani, B; Carboni, C; Valente, M; Lerone, M; D'Arca, S U

    1980-06-01

    From 1975 to 1979 the Rome Microcythaemia Centre carried out four health education campaigns and thalassaemia screenings among students of the intermediate schools throughout Latium, under the auspices and with the financial support of the Health Authorities of the Latium region. This project is aimed at avoiding reproduction by pairs of thalassaemia carriers and the birth of homozygous children. During the four campaigns 138 501 students were examined, that is, 70 to 76% of those enrolled. Of these 3343 were found to be thalassaemic. Thus the overall prevalence of thalassaemia in Latium is 2.41%, with minor fluctuations from one province to another and, above all, a slight, though definite, trend towards higher values in the southern part of Latium bordering on Campania. The screening was welcomed by the population and the thalassaemic families, there were no detectable negative side-effects, and it resulted in an increased awareness of the problem of the thalassaemias.

  14. Targeted sequencing identifies novel variants involved in autosomal recessive hereditary hearing loss in Qatari families.

    PubMed

    Alkowari, Moza K; Vozzi, Diego; Bhagat, Shruti; Krishnamoorthy, Navaneethakrishnan; Morgan, Anna; Hayder, Yousra; Logendra, Barathy; Najjar, Nehal; Gandin, Ilaria; Gasparini, Paolo; Badii, Ramin; Girotto, Giorgia; Abdulhadi, Khalid

    2017-05-04

    Hereditary hearing loss is characterized by a very high genetic heterogeneity. In the Qatari population the role of GJB2, the worldwide HHL major player, seems to be quite limited compared to Caucasian populations. In this study we analysed 18 Qatari families affected by non-syndromic hearing loss using a targeted sequencing approach that allowed us to analyse 81 genes simultaneously. Thanks to this approach, 50% of these families (9 out of 18) resulted positive for the presence of likely causative alleles in 6 different genes: CDH23, MYO6, GJB6, OTOF, TMC1 and OTOA. In particular, 4 novel alleles were detected while the remaining ones were already described to be associated to HHL in other ethnic groups. Molecular modelling has been used to further investigate the role of novel alleles identified in CDH23 and TMC1 genes demonstrating their crucial role in Ca2+ binding and therefore possible functional role in proteins. Present study showed that an accurate molecular diagnosis based on next generation sequencing technologies might largely improve molecular diagnostics outcome leading to benefits for both genetic counseling and definition of recurrence risk. Copyright © 2017 Elsevier B.V. All rights reserved.

  15. Sociodemographic Factors Associated with Tobacco Smoking among Intermediate and Secondary School Students in Jazan Region of Saudi Arabia

    ERIC Educational Resources Information Center

    Gaffar, Abdelrahim Mutwakel; Alsanosy, Rashad Mohammed; Mahfouz, Mohamed Salih

    2013-01-01

    Background: The objectives of this study were to (i) determine the prevalence of and characteristics associated with tobacco smoking; (ii) identify the factors associated with tobacco smoking; and (iii) evaluate the association between tobacco smoking and khat chewing among intermediate and secondary school students in Jazan Region, Saudi Arabia.…

  16. "I Feel I'm Important": Successful Collaborative Teaching and Learning in a New Zealand Intermediate School

    ERIC Educational Resources Information Center

    Martin, Rachel; Williams, Judy

    2012-01-01

    The investigation examined a collaborative teaching and learning house structure at a New Zealand intermediate (or middle) school. Using observations, questionnaires, and interviews, we explored the perceptions of staff, children, and parents about the educational value of such a model and whether it meets the principles of good education for the…

  17. The Development of Ontario Schools: Intermediate and Senior Divisions--1984 (OSIS) and the Initial Phase of Its Implementation.

    ERIC Educational Resources Information Center

    Leithwood, K.; And Others

    This case study examines the development and implementation of secondary education policy in Ontario as defined in "Ontario Schools: Intermediate and Senior Divisions (OSIS)--1984." Data were gathered for the period from 1980 when the Secondary Education Review Project (SERP) was initiated, to 1984 when the policy outlined in OSIS was to…

  18. Sociodemographic Factors Associated with Tobacco Smoking among Intermediate and Secondary School Students in Jazan Region of Saudi Arabia

    ERIC Educational Resources Information Center

    Gaffar, Abdelrahim Mutwakel; Alsanosy, Rashad Mohammed; Mahfouz, Mohamed Salih

    2013-01-01

    Background: The objectives of this study were to (i) determine the prevalence of and characteristics associated with tobacco smoking; (ii) identify the factors associated with tobacco smoking; and (iii) evaluate the association between tobacco smoking and khat chewing among intermediate and secondary school students in Jazan Region, Saudi Arabia.…

  19. A Comparative Study of EFL Teachers' and Intermediate High School Students' Perceptions of Written Corrective Feedback on Grammatical Errors

    ERIC Educational Resources Information Center

    Jodaie, Mina; Farrokhi, Farahman; Zoghi, Masoud

    2011-01-01

    This study was an attempt to compare EFL teachers' and intermediate high school students' perceptions of written corrective feedback on grammatical errors and also to specify their reasons for choosing comprehensive or selective feedback and some feedback strategies over some others. To collect the required data, the student version of…

  20. A Qatari perspective on women in the engineering pipeline: an exploratory study

    NASA Astrophysics Data System (ADS)

    Fauziah Sulaiman, Noor; AlMuftah, Hend

    2010-10-01

    Under-representation of women in engineering has received a great deal of attention, but remained limited largely to a Western context. Thus, this article aims to unveil the barriers to progress, tracking the performance and the emerging trend of success at the undergraduate level of women in engineering in a different cultural dimension. Secondary research, particularly statistical data of female undergraduate engineering students at Qatar University (QU), is used in this study. Findings show that the booming economic development and access to modern education are the key drivers that change the position of women in Qatari society. A shift away from a masculine-dominated society to a more balance masculine/feminine society was identified as the impetus for better enrolment and achievement of female engineering students in Qatar. Similar to the trend in the USA, recruitment and not retention was the reason behind the under-representation of female undergraduate engineering students at QU.

  1. A pilot study on metabolic syndrome and its associated features among Qatari schoolchildren

    PubMed Central

    Rizk, Nasser; Amin, Mona; Yousef, Mervat

    2011-01-01

    Aim: This pilot study aimed to evaluate the individual features of the metabolic syndrome (MeS) and its frequency in Qatari schoolchildren aged 6–12 years. Background: MeS has a strong future risk for development of diabetes and cardiovascular diseases. Childhood obesity is increasing the likelihood of MeS in children. Methods: The associated features of MeS were assessed in 67 children. They were recruited from the outpatient pediatric clinic at Hamad Medical Corporation, Qatar. Height, weight, and waist circumference were measured and body mass index was calculated for each child. Fasting blood glucose, total cholesterol, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol and triglycerides (TG) were measured. MeS was defined according to the National Cholesterol Education Program Adult Treatment Panel III (NCEP-III) which was modified by Cook with adjustment for fasting glucose to ≥5.6 mM according to recommendations from the American Diabetes Association. Results: The overall prevalence of MeS according to NCEP-III criteria was 3.0% in children aged 6–12 years. Overweight and obesity was 31.3% in children aged 6–12 years, according to the International Obesity Task Force criteria. The prevalence of MeS was 9.5% in overweight and obese subjects. Increased TG levels represented the most frequent abnormality (28.4%) in metabolic syndrome features in all subjects, followed by HDL-C (19.4%) in all subjects. Conclusion: Increased TG levels and low HDL-C were the most frequent components of this syndrome. This study showed a significant prevalence of MeS and associated features among overweight and obese children. The overall prevalence of MeS in Qatari children is in accordance with data from several other countries. PMID:21845059

  2. Hypodontia prevalence and distribution pattern in a group of Qatari orthodontic and pediatric patients: A retrospective study

    PubMed Central

    Abed Al Jawad, Feras H.; Al Yafei, Hanan; Al Sheeb, Muneera; Al Emadi, Buthaina; Al hashimi, Najah

    2015-01-01

    Objectives: The aim of this study was to investigate the prevalence and distribution of hypodontia in the permanent teeth among a group of the Qatari sample and to compare the present results with findings from other populations. Materials and Methods: Records of 1269 Qatari patients (674 females; mean age 11.8 ± 2.3 and 595 males; mean age 11.4 ± 2.2) which included panoramic radiographs were examined to identify hypodontia. All permanent teeth were investigated except third molars. Results: The prevalence of hypodontia was 6.2% (females 8% and males 4.2%; P < 0.05). The majority of patients had one or two missing teeth. There were no significant differences between right and left sides for any particular tooth. The most frequently missing teeth were maxillary lateral incisors (36.2%), followed by mandibular second premolar (32.6%) and maxillary second premolar (20.2%). Hypodontia was more commonly found unilaterally than bilaterally (63.2% and 44.3%; respectively). Conclusions: The prevalence of hypodontia in a group of the Qatari population was within the average value of the majority of published studies in the literature. Hypodontia was significantly more prevalent in females. Although less prevalent, considerable cases of bilateral missing were found in the present study, which necessitates the urgent need for intervention and multi-disciplinary team approach for management. PMID:26038662

  3. The present status of geography education in boys' intermediate schools of Riyadh, Saudi Arabia

    NASA Astrophysics Data System (ADS)

    Al-Gahtany, Abdulrahman Mohammed

    The purpose of this study was to describe the present status of geography education in boys' intermediate schools in Riyadh, Saudi Arabia as perceived by geography teachers and supervisors; that is, to investigate the objectives, content, methods of teaching, tools and resources that are available and used in classrooms, evaluation techniques, and problems encountered in the teaching of geography. To collect data from this representative sample population, a questionnaire was developed by the researcher specifically for this study. Questionnaire data was collected from 19 social studies supervisors and 213 geography teachers. Percentages, frequencies, means, and standard deviations were computed for each questionnaire item. Chi Square tests were applied to determine if any significant differences could be identified between the observed and expected responses of supervisors and teachers. Major findings of the study indicated that both supervisors and teachers tend to strongly support the identified geography objectives. Most teachers and supervisors also indicated that the current geography curriculum contains enough information about Saudi Arabia, the Arabic world, and the Islamic world. In addition, the also indicated that geography content promotes a sense of patriotism and cultural pride. Responses indicated that educators see deficiencies in the content: it does not focus sufficiently on current events nor on developing student skills such as research and technical skills like drawing maps. Lecture and discussion are the most commonly used strategies in the teaching of geography. Field trips, role-playing, scientific competitions, scientific games, solving problems, and individual learning are less commonly used. Teaching tools most commonly used are wall maps and earth globes, whereas the use of geographical transparencies, models, and instruments is not common. Most of the teachers do lot use computers in their teaching. Evaluation techniques depend

  4. Maternal knowledge, attitude and practice on folic acid intake among Arabian Qatari women.

    PubMed

    Bener, Abdulbari; Al Maadid, Mohammed G A; Al-Bast, Daoud A E; Al-Marri, Saleh

    2006-01-01

    Periconceptional folic acid supplementation is effective in preventing primary and secondary neural tube defects (NTDs) and other congenital defects. It is important to estimate folate intake and knowledge in women of child-bearing age, in relation to risk of congenital anomalies. The aim of this study was to determine the level of knowledge about the usefulness of periconceptional folic acid supplementation in a sample of women in the child-bearing age. This is a cross-sectional survey. Eleven primary health care centers and women's hospital in Qatar. A multistage sampling design was used and a representative sample of 1,800 Qatari women aged between 18 and 45 years were surveyed during the period June to November 2004. One thousand four hundred and eighty women (82.2%) expressed their consent to participate in this study. A confidential, anonymous questionnaire was completed by the selected subjects assessing folic acid awareness. Questionnaires were administered to women who were seeking routine antenatal care at health centers and Women's Hospital. Questions covered knowledge and use of folic acid supplements, pregnancy intention, and demographic and socioeconomic characteristics. Factors affecting study outcomes were examined individually by computing crude odd ratios and adjusted for other covariates using unconditional logistic regression. Out of 1480 women surveyed, 53.7% of them reported that they heard of folate. Of these, only half of the subjects knew that folate was something important. Overall, 20.3% of the respondents took folic acid. The most common information sources on folate were physicians (63.4%), and newspapers/magazine/books (21.7%). From those who heard of folate, only 14% knew that it can prevent birth defects. 40.6% of the subjects who heard folate were aware that green leafy vegetables were fortified with folic acid. In univariate analysis, awareness of folic acid was significantly associated with education of mother. Again, higher

  5. Saudi Intermediate School EFL Teachers' Views in the Kingdom of Saudi Arabia of the Multiple Intelligences Theory as an Inclusive Pedagogy

    ERIC Educational Resources Information Center

    Kentab, Mohammad Yousef

    2016-01-01

    In this study, the researcher attempted to shed light on Saudi intermediate school EFL teachers' views of the multiple intelligences theory as an inclusive pedagogy. The purpose of this study was to investigate the impact of multiple intelligences on Saudi intermediate students' learning of EFL. The study also tried to illustrate the main…

  6. A Behavior Change Program To De-Escalate Fighting in Intermediate Grades of an Elementary School.

    ERIC Educational Resources Information Center

    Sthair, Vincent L.

    A plan to de-escalate fighting behaviors at an inner-city elementary school was implemented. It is believed that factors contributing to the problem were: low socio-economic status; a lack of parental supervision at home; a lack of parental involvement at school; a high level of criminal activity surrounding the schools; overcrowded class areas;…

  7. Applying Literature in the Elementary School: Shakespeare in the Intermediate Grades.

    ERIC Educational Resources Information Center

    Halkitis, Perry N.; Hoffman, Mala

    1992-01-01

    This program, which applies William Shakespeare's works for gifted intermediate level students, involves student reading of plays, students and teachers reading together and discussing scenes, individual students rereading the plays, student projects applying their knowledge of the play, and evaluation of play productions. (JDD)

  8. Applying Literature in the Elementary School: Shakespeare in the Intermediate Grades.

    ERIC Educational Resources Information Center

    Halkitis, Perry N.; Hoffman, Mala

    1992-01-01

    This program, which applies William Shakespeare's works for gifted intermediate level students, involves student reading of plays, students and teachers reading together and discussing scenes, individual students rereading the plays, student projects applying their knowledge of the play, and evaluation of play productions. (JDD)

  9. Enrich the Physics Curriculum Scheduled for Students of Intermediate School E-Learning and Its Effectiveness in Scientific Thinking and Their Attitude towards the Development of Physics

    ERIC Educational Resources Information Center

    Hameed, Saddam Mohammed; Mohammed, Essam Mahmoud

    2016-01-01

    The current research aims know the effectiveness of enriching the physics curriculum for students in middle school electronic learning in the development of their thinking and scientific their direction towards physics, sample formed from second grade students in Sinae intermediate school 64 students (32) student as experimental group & (32)…

  10. Bases para el Curriculum del Primer Ciclo de las Escuelas de Nivel Intermedio (Bases for the First Term Curriculum in Intermediate Schools).

    ERIC Educational Resources Information Center

    Fermin Mignone, Emilio; And Others

    This curriculum guide for intermediate schools in Argentina begins with a discussion of the historical development of such schools and of their place in the overall educational scheme. The section on the curriculum provides detailed information on objectives, content, and activities; philosophical, political, sociological, methodological, and…

  11. Medical Advice for Sick-reported Students (MASS) in intermediate vocational education schools: design of a controlled before-and-after study.

    PubMed

    Van der Vlis, Madelon K; Lugtenberg, Marjolein; Vanneste, Yvonne T M; Berends, Wenda; Mulder, Wico; Bannink, Rienke; Van Grieken, Amy; Raat, Hein; de Kroon, Marlou L A

    2017-06-29

    School absenteeism, including medical absenteeism, is associated with early school dropout and may result in physical, mental, social and work-related problems in later life. Especially at intermediate vocational education schools, high rates of medical absenteeism are found. In 2012 the Dutch intervention 'Medical Advice for Sick-reported Students' (MASS), previously developed for pre-vocational secondary education, was adjusted for intermediate vocational education schools. The aim of the study outlined in this paper is to evaluate the effectiveness of the MASS intervention at intermediate vocational education schools in terms of reducing students' medical absenteeism and early dropping out of school. Additionally, the extent to which biopsychosocial and other factors moderate the effectiveness of the intervention will be assessed. A controlled before-and-after study will be conducted within Intermediate Vocational Education schools. Schools are allocated to be an intervention or control school based on whether the schools have implemented the MASS intervention (intervention schools) or not (control schools). Intervention schools apply the MASS intervention consisting of active support for students with medical absenteeism provided by the school including a consultation with the Youth Health Care (YHC) professional if needed. Control schools provide care as usual. Data will be collected by questionnaires among students in both groups meeting the criteria for extensive medical absenteeism (i.e. 'reported sick four times in 12 school weeks or for more than six consecutive school days' at baseline and at 6 months follow-up). Additionally, in the intervention group a questionnaire is completed after each consultation with a YHC professional, by both the student and the YHC professional. Primary outcome measures are duration and cumulative incidence of absenteeism and academic performances. Secondary outcome measures are biopsychosocial outcomes of the students. It

  12. The Trace Element Composition of Plankton and Dust in the Qatari EEZ

    NASA Astrophysics Data System (ADS)

    Turner, J.; Murray, J. W.; Yigiterhan, O.; Al-Ansari, I. S.; Al-Ansi, M.; Abdel-Moati, M.; Paul, B.; Nelson, A.

    2015-12-01

    We present data on elemental concentrations of plankton net tow samples from the Exclusive Economic Zone (EEZ) of Qatar in the Arabian Gulf as part of a broader study of biogenic and lithogenic influences on particulate trace metal concentrations in the surface ocean. There are relatively few analyses of planktonic trace metals and their associated role in the biogeochemical system. We had the opportunity to investigate the composition of plankton in a region heavily affected by dust, a significant factor for phytoplankton growth. Our samples were collected from 2012 to 2015 using trace metal clean net tows with mesh sizes of 50 and 200 microns for measurements of phytoplankton and zooplankton, respectively. Samples were totally digested and analyzed by inductively coupled plasma-mass spectroscopy (ICP-MS). The biogenic portion was determined by subtracting the lithogenic portion from the total concentration. The lithogenic fraction was defined as the concentration of aluminum in the sample multiplied by a [Me]/Al ratio. Using average Qatari dust for these ratios generated a significant amount of overcorrection, so ratios were established using average upper continental crust (UCC). This method still caused some overcorrection for the lithogenic portion resulting in negative excess values for barium, molybdenum, and lead. These same elements showed the least consistency between measurements. For the other elements, a relative stoichiometry for plankton was determined as Fe > Cu ≈ Zn > As ≈ Cr ≈ Mn ≈ Ni ≈ V > Cd ≈ Co. We also found a significant near shore enrichment for 9 out of 13 elements analyzed, indicative of a possible influence of coastal processes.

  13. Knowledge, attitude and practices of Qatari patients with type 2 diabetes mellitus.

    PubMed

    Kheir, Nadir; Greer, William; Yousif, Adil; Al Geed, Hajer; Al Okkah, Randa

    2011-06-01

    Patient compliance with their medications and their ability for self-management in type 2 diabetes mellitus (T2DM) is a growing cause of concern to healthcare providers. Knowledge about diabetes, attitude towards the condition and time management with respect to the condition (practice), collectively known as KAP, are known to affect compliance and play an important part in diabetes management. We aimed to describe the knowledge, attitude, practice and psychological status of adult Qatari patients with T2DM, and to explore the interaction between these and other patient-related factors which could impact on the ability of the patients to manage their diabetes and to achieve desirable health outcomes. A questionnaire (the Diabetes Habits and Beliefs Questionnaire, DHBQ) was used to investigate the level and relationship between knowledge, attitude, general practice and psychological status of patients with T2DM. The data was collected in face-to-face interviews with patients visiting the diabetic clinic at a tertiary hospital in Qatar during the period January 2008 to March 2009. There were significant differences in attitude and knowledge between educational levels. Knowledge and attitude were highly correlated and the psychological status of the patient was positively associated with both knowledge and attitude. There was generally poor practice of regularly inspecting feet to detect signs of neuropathy, taking medication in relation to meals, modifying doses when necessary and setting goals for therapy. The data provided can assist pharmacists and other healthcare practitioners in tailoring educational programmes aimed at improving diabetes control. © 2011 The Authors. IJPP © 2011 Royal Pharmaceutical Society.

  14. Metabolic syndrome among obese Qataris attending primary health care centers in Doha, 2010.

    PubMed

    Ismail, Mansoura F S

    2012-01-01

    To determine the prevalence of metabolic syndrome among obese patients using the IDF definition and to identify factors that are associated with it. A cross-sectional randomized study was conducted at four primary care centers inside Doha, Qatar. One hundred and thirty-six Adults, ≥ 18 Qatari obese patients, were chosen by systematic random sampling. They were interviewed and screened for the presence of metabolic syndrome, which was diagnosed according to the International Diabetes Federation criteria: An abdominal circumference ≥ 94 cm in males or ≥ 80 cm in females, plus any two of the following: HDL cholesterol < 1.03 mmol / mL (< 40 mg / dL) [males] or < 1.3 mmol / mL (< 50 mg / dL) [females], Triglycerides ≥ 1.7 mmol / mL (≥150 mg / dL), Blood pressure ≥ 130 / 85 mmHg or the patient receiving antihypertensive treatment and baseline glycemia > 5.6 mmol / mL (> 100 mg / dL), or previously-diagnosed type 2 diabetes mellitus. The overall prevalence of the metabolic syndrome among obese patients was 46.3%. The prevalence was higher in females (50%) than in males (42.4%). It was seen to increase with increasing body mass index class, from class 1 to class 2. The prevalence of metabolic comorbidities of abnormal waist circumference, raised blood pressure, raised fasting blood glucose, high triglycerides, and reduced high density lipoprotein was 88.2, 42.6, 32.4, 31.6, and 27.9%, respectively. Based on the logistic regression multivariable analysis, increasing age and being diabetic were the only significant associated factors that influenced the risk of having the metabolic syndrome. The prevalence of the metabolic syndrome was high, and the highest comorbidities were abnormal waist circumference and high blood pressure. Diabetes and increasing age were the only significant risk factors of having this syndrome.

  15. Lifestyle Patterns Are Associated with Elevated Blood Pressure among Qatari Women of Reproductive Age: A Cross-Sectional National Study

    PubMed Central

    Al Thani, Mohammed; Al Thani, Al Anoud; Al-Chetachi, Walaa; Al Malki, Badria; Khalifa, Shamseldin A. H.; Bakri, Ahmad Haj; Hwalla, Nahla; Nasreddine, Lara; Naja, Farah

    2015-01-01

    Women of childbearing age are particularly vulnerable to the adverse effects of elevated blood pressure (BP), with dietary and lifestyle habits being increasingly recognized as important modifiable environmental risk factors for this condition. Using data from the National STEPwise survey conducted in Qatar in year 2012, we aimed to examine lifestyle patterns and their association with elevated BP among Qatari women of childbearing age (18–45 years). Socio-demographic, lifestyle, dietary, anthropometric and BP data were used (n = 747). Principal component factor analysis was applied to identify the patterns using the frequency of consumption of 13 foods/food groups, physical activity level, and smoking status. Multivariate logistic regression analyses were used to evaluate the association of the identified lifestyle patterns with elevated BP and to examine the socio-demographic correlates of these patterns. Three lifestyle patterns were identified: a “healthy” pattern characterized by intake of fruits, natural juices, and vegetables; a “fast food & smoking” pattern characterized by fast foods, sweetened beverages, and sweets, in addition to smoking; and a “traditional sedentary” pattern which consisted of refined grains, dairy products, and meat in addition to low physical activity. The fast food & smoking and the traditional & sedentary patterns were associated with an approximately 2-fold increase in the risk of elevated BP in the study population. The findings of this study highlight the synergistic effect that diet, smoking and physical inactivity may have on the risk of elevated BP among Qatari women. PMID:26371041

  16. Lifestyle Patterns Are Associated with Elevated Blood Pressure among Qatari Women of Reproductive Age: A Cross-Sectional National Study.

    PubMed

    Al Thani, Mohammed; Al Thani, Al Anoud; Al-Chetachi, Walaa; Al Malki, Badria; Khalifa, Shamseldin A H; Bakri, Ahmad Haj; Hwalla, Nahla; Nasreddine, Lara; Naja, Farah

    2015-09-09

    Women of childbearing age are particularly vulnerable to the adverse effects of elevated blood pressure (BP), with dietary and lifestyle habits being increasingly recognized as important modifiable environmental risk factors for this condition. Using data from the National STEPwise survey conducted in Qatar in year 2012, we aimed to examine lifestyle patterns and their association with elevated BP among Qatari women of childbearing age (18-45 years). Socio-demographic, lifestyle, dietary, anthropometric and BP data were used (n = 747). Principal component factor analysis was applied to identify the patterns using the frequency of consumption of 13 foods/food groups, physical activity level, and smoking status. Multivariate logistic regression analyses were used to evaluate the association of the identified lifestyle patterns with elevated BP and to examine the socio-demographic correlates of these patterns. Three lifestyle patterns were identified: a "healthy" pattern characterized by intake of fruits, natural juices, and vegetables; a "fast food & smoking" pattern characterized by fast foods, sweetened beverages, and sweets, in addition to smoking; and a "traditional sedentary" pattern which consisted of refined grains, dairy products, and meat in addition to low physical activity. The fast food & smoking and the traditional & sedentary patterns were associated with an approximately 2-fold increase in the risk of elevated BP in the study population. The findings of this study highlight the synergistic effect that diet, smoking and physical inactivity may have on the risk of elevated BP among Qatari women.

  17. Introducing Students to the Competing Schools of Thought in Intermediate Macroeconomics.

    ERIC Educational Resources Information Center

    Smith, Harlan M., II

    1997-01-01

    Illustrates how, using introductory-level microeconomic models, an instructor can show various economic theorists' explanations of short run employment and output fluctuations. Identifies the competing schools of thought as old Keynesian, new Keynesian, and new Classical (which includes real business cycle theorists). Includes illustrative graphs…

  18. Introducing Students to the Competing Schools of Thought in Intermediate Macroeconomics.

    ERIC Educational Resources Information Center

    Smith, Harlan M., II

    1997-01-01

    Illustrates how, using introductory-level microeconomic models, an instructor can show various economic theorists' explanations of short run employment and output fluctuations. Identifies the competing schools of thought as old Keynesian, new Keynesian, and new Classical (which includes real business cycle theorists). Includes illustrative graphs…

  19. Positive Behavior Supports: A Study of Implementation at the Intermediate School Level

    ERIC Educational Resources Information Center

    Hasson, Robert C., Jr.

    2011-01-01

    Public schools are faced with the ever-increasing pressure of maintaining a safe learning environment while continuously improving student performance. Also, there has been a growing concern among administrators and teachers for implementing an effective discipline plan that will keep students in class and engaged in learning as much as possible.…

  20. A Mixed Methods Explanatory Study of Intermediate School Collaboration and Inclusion

    ERIC Educational Resources Information Center

    Sanchez, Sandra J.

    2012-01-01

    This mixed methods explanatory study addressed the problem of continuing disparity in achievement between students with special needs and their peers in the educational setting, despite mandates requiring schools to educate these students in the least restrictive environment. The purpose of this study was to determine the types and extent of…

  1. Integrated Language and Content Instruction in Qatar Independent Schools: Teachers' Perspectives

    ERIC Educational Resources Information Center

    Ellili-Cherif, Maha

    2014-01-01

    The aim of this study is to explore teachers' attitudes towards the shift to English as a medium of instruction in Qatari Independent schools. It focuses on the advantages and disadvantages of this approach for teachers and students, and the challenges they face in the process of its implementation. Data for the study were collected by means of a…

  2. Intermediate photovoltaic system application experiment operational performance report. Volume 4: Beverly High School, Beverly, Mass.

    NASA Astrophysics Data System (ADS)

    1982-01-01

    Performance data are presented for the months of November and December, 1981 for a photovoltaic power supply at a Massachusetts school building. The ata include: monthly and daily electrical energy produced; monthly and daily solar energy received; monthly and daily array efficiency; energy produced as a function of power level, voltage, cell temperature, and hour of the day; input, output, and efficiency of two power conditioner units and for the total power conditioning system; energy supplied by the photovoltaic system to the load during each day and month; photovoltaic system efficiency; capacity factor; daily system availability; monthly and hourly insolation; heating and cooling degree days; number of freeze-thaw cycles per month; monthly and hourly ambient temperature; monthly and hourly wind speed; wind direction distribution; hourly cell temperature; and data acquisition mode and recording interval plot.

  3. Intermediate photovoltaic system application experiment operational performance report. Volume 4, for Beverly High School, Beverly, MA

    SciTech Connect

    Not Available

    1982-01-01

    Performance data are presented for the months of November and December, 1981 for a photovoltaic power supply at a Massachusetts school building. The data include: monthly and daily electrical energy produced; monthly and daily solar energy received; monthly and daily array efficiency; energy produced as a function of power level, voltage, cell temperature, and hour of the day; input, output, and efficiency of two power conditioner units and for the total power conditioning system; energy supplied by the photovoltaic system to the load during each day and month; photovoltaic system efficiency; capacity factor; daily system availability; monthly and hourly insolation; heating and cooling degree days; number of freeze/thaw cycles per month; monthly and hourly ambient temperature; monthly and hourly wind speed; wind direction distribution; hourly cell temperature; and data acquisition mode and recording interval plot. (LEW)

  4. Intermediate treatments

    Treesearch

    John R. Jones; Wayne D. Shepperd

    1985-01-01

    Intermediate treatments are those applied after a new stand is successfully established and before the final harvest. These include not only intermediate cuttings - primarily thinning - but also fertilization, irrigation, and protection of the stand from damaging agents.

  5. A PROJECT TO PROVIDE TEACHER-SUPERVISOR TRAINING NEEDED TO IMPLEMENT IN 12 SCHOOLS SERVICING DISADVANTAGED PUPILS THE PHILOSOPHY, OBJECTIVES, CURRICULUM, BEING DEVELOPED FOR DISADVANTAGED PUPILS IN THE NEW TYPE OF INTERMEDIATE (MIDDLE)SCHOOL.

    ERIC Educational Resources Information Center

    TYREE, MARSHALL

    TWO OF THE 10 SESSIONS OF A TEACHER AND SUPERVISOR TRAINING PROGRAM IN PREPARATION FOR THE OPENING OF SOME OF THE NEW YORK CITY PILOT INTERMEDIATE SCHOOLS WERE EVALUATED. DATA CONSISTED OF OBSERVER REPORTS AND PARTICIPANTS' RESPONSES TO QUESTIONNAIRES. THE PARTICIPANTS MAINTAINED A HIGH LEVEL OF ACHIEVEMENT AND COOPERATION DURING BOTH SESSIONS.…

  6. International note: Prediction of mathematics work ethic and performance from behavioral, normative, and control beliefs among Qatari adolescents.

    PubMed

    Areepattamannil, Shaljan; Abdelfattah, Faisal; Mahasneh, Randa Ali; Khine, Myint Swe; Welch, Anita G; Melkonian, Michael; Al Nuaimi, Samira Ahmed

    2016-01-01

    Over half-a-million adolescents take part in each cycle of the Program for International Student Assessment (PISA). Yet often, researchers and policy makers across the globe tend to focus their attention primarily on the academic trajectories of adolescents hailing from highly successful education systems. Hence, a vast majority of the adolescent population who regionally and globally constitute the 'long tail of underachievement' often remain unnoticed and underrepresented in the growing literature on adolescents' academic trajectories. The present study, therefore, explored the relations of dispositions toward mathematics, subjective norms in mathematics, and perceived control of success in mathematics to mathematics work ethic as well as mathematics performance; and the mediational role of mathematics work ethic in the association between dispositional, normative, and control beliefs and mathematics performance among adolescents in one of the lowest performing education systems, Qatar. Structural equation modeling (SEM) analyses revealed that Qatari adolescents' dispositional, normative, and control beliefs about mathematics were significantly associated with their mathematics work ethic and mathematics performance, and mathematics work ethic significantly mediated the relationship between dispositional, normative, and control beliefs about mathematics and mathematics performance. However, multi-group SEM analyses indicated that these relationships were not invariant across the gender and the SES groups. Copyright © 2015 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

  7. Prevalence of Virulence/Stress Genes in Campylobacter jejuni from Chicken Meat Sold in Qatari Retail Outlets.

    PubMed

    Abu-Madi, Marawan; Behnke, Jerzy M; Sharma, Aarti; Bearden, Rebecca; Al-Banna, Nadia

    2016-01-01

    Chicken meat from the shelves of supermarkets in Qatar was tested for the presence of Campylobacter spp. and the presence of five virulence genes (htrB, cdtB, clpP, cadF and ciaB) was assessed in isolates. Forty eight percent of the chickens provided for supermarkets by Saudi (53%) and Qatari (45.9%) producers were found to be contaminated and the most important factor affecting the overall prevalence of contaminated chickens was the store from which chicken samples originated. Variation in prevalence of Campylobacter in chicken meat from different stores was evident even when the same producer supplied the three stores in our survey. Differences in the prevalence and in the combinations of virulence genes in isolates that can and cannot grow in a classic maintenance medium (Karmali) were identified, providing a starting point for linking presence/absence of particular virulence genes with actual in vivo virulence and pathogenicity. Because of the relatively low infective doses of Campylobacter that are required to initiate infection in humans, it will be important to explore further the relationships we identified between certain Campylobacter virulence genes and their capacity for survival in poultry meat, and hence their contribution to the incidence of campylobacteriosis.

  8. Hispanic American Heritage, Intermediate.

    ERIC Educational Resources Information Center

    Shepherd, Mike

    This resource book features the cultural heritage of Hispanics living within the United States and includes ideas, materials, and activities to be used with students in the intermediate grades and middle school. This book explores the definition of the term "Hispanic Americans" and suggests a multilayered population with a variety of cultural…

  9. Hispanic American Heritage, Intermediate.

    ERIC Educational Resources Information Center

    Shepherd, Mike

    This resource book features the cultural heritage of Hispanics living within the United States and includes ideas, materials, and activities to be used with students in the intermediate grades and middle school. This book explores the definition of the term "Hispanic Americans" and suggests a multilayered population with a variety of cultural…

  10. A ‘High Risk’ Lifestyle Pattern Is Associated with Metabolic Syndrome among Qatari Women of Reproductive Age: A Cross-Sectional National Study

    PubMed Central

    Al Thani, Mohammed; Al Thani, Al Anoud; Al-Chetachi, Walaa; Al Malki, Badria; Khalifa, Shamseldin A. H.; Haj Bakri, Ahmad; Hwalla, Nahla; Nasreddine, Lara; Naja, Farah

    2016-01-01

    This study investigated the effect of lifestyle patterns, as a combination of diet, physical activity and smoking, on Metabolic Syndrome (MetS) among Qatari women of childbearing age (n = 418), a population group particularly vulnerable to the health sequela of this syndrome. Using data from the National WHO STEPwise survey conducted in Qatar in 2012, Principal Component Factor Analysis was performed to derive lifestyle patterns with survey variables related to the frequency of consumption of 13 foods/food groups, physical activity levels, and smoking status. MetS was diagnosed using ATPIII criteria. Three lifestyle patterns were identified: ‘High Risk’ pattern, characterized by intakes of fast foods, sweets and sugar sweetened beverages, in addition to lower levels of physical activity and higher smoking prevalence; ‘Prudent’ pattern, driven mainly by higher intakes of fruits, vegetables, fish, and whole grains; and ‘Traditional’ pattern which included beans, meat, dairy products, and a low prevalence of smoking. Among these three lifestyle patterns, only the ‘High Risk’ was associated with MetS, whereby subjects belonging to the third tertile of this pattern’s score had 2.5 times the odds of MetS compared to those belonging to the first tertile. The findings of this study demonstrated the synergy among high risk behaviors among Qatari women in increasing the odds of MetS; the latter being a major risk factor for cardiovascular diseases. PMID:27271596

  11. A 'High Risk' Lifestyle Pattern Is Associated with Metabolic Syndrome among Qatari Women of Reproductive Age: A Cross-Sectional National Study.

    PubMed

    Al Thani, Mohammed; Al Thani, Al Anoud; Al-Chetachi, Walaa; Al Malki, Badria; Khalifa, Shamseldin A H; Haj Bakri, Ahmad; Hwalla, Nahla; Nasreddine, Lara; Naja, Farah

    2016-06-02

    This study investigated the effect of lifestyle patterns, as a combination of diet, physical activity and smoking, on Metabolic Syndrome (MetS) among Qatari women of childbearing age (n = 418), a population group particularly vulnerable to the health sequela of this syndrome. Using data from the National WHO STEPwise survey conducted in Qatar in 2012, Principal Component Factor Analysis was performed to derive lifestyle patterns with survey variables related to the frequency of consumption of 13 foods/food groups, physical activity levels, and smoking status. MetS was diagnosed using ATPIII criteria. Three lifestyle patterns were identified: 'High Risk' pattern, characterized by intakes of fast foods, sweets and sugar sweetened beverages, in addition to lower levels of physical activity and higher smoking prevalence; 'Prudent' pattern, driven mainly by higher intakes of fruits, vegetables, fish, and whole grains; and 'Traditional' pattern which included beans, meat, dairy products, and a low prevalence of smoking. Among these three lifestyle patterns, only the 'High Risk' was associated with MetS, whereby subjects belonging to the third tertile of this pattern's score had 2.5 times the odds of MetS compared to those belonging to the first tertile. The findings of this study demonstrated the synergy among high risk behaviors among Qatari women in increasing the odds of MetS; the latter being a major risk factor for cardiovascular diseases.

  12. Mathematics Instruction in Inner-City Intermediate Schools: An Inductive Approach to Identifying Problems and Crafting Solutions. Research Report #8.

    ERIC Educational Resources Information Center

    Manning, Philip; Matthews, Sarah H.

    An exploration of sources of gang activity in an urban area used ethnographic research with researchers posing as mathematics tutors for 1 year in a school comprising seventh and eighth grades. The "tutors" attended six eighth grade mathematics classes and acted as assistants to the teacher. The classes of 25 to 30 students lasted 40 minutes and…

  13. The Relationship between the Boehm and AIMSweb on Kindergarten Student Achievement in One Northern Michigan Intermediate School District

    ERIC Educational Resources Information Center

    O'Hearn, Emily

    2013-01-01

    Kindergarten students are asked to perform at a level formerly expected of first grade students and are expected to be well on their way to reading (Bassard & Boehm, 2007). With tight school budgets, site leaders must choose wisely about allocation of resources and determine the most effective means of helping students, especially those…

  14. Narrowing the Achievement Gap: Factors That Support English Learner and Hispanic Student Academic Achievement in an Urban Intermediate School

    ERIC Educational Resources Information Center

    Flores, Patricia Arleen

    2010-01-01

    A persistent and pervasive disparity in academic achievement exists between ethnic minority and English Learner students and their White and Asian peers. This qualitative single-case study of a high-poverty, high-performing middle school focused on the cultural norms, practices, and programs that were perceived to be contributing to narrowing the…

  15. The Effectiveness of a School-Wide Positive Behavior Support Plan on Office Discipline Referrals at the Primary, Intermediate, and Middle School Level

    ERIC Educational Resources Information Center

    Jones, Quincy L.

    2013-01-01

    Schools across the nation are facing the challenge of addressing behavioral issues with students. Traditional approaches to discipline have been ineffective in improving student behavior. The passing of the No Child Left Behind Act (NCLB) of 2001 and revisions of the Individual Disabilities Education Improvement Act (IDEIA) of 2004 require schools…

  16. Project on Academic Striving: The Moderation of Stress in the Lives of the Students of an Urban Intermediate School. A Project To Coordinate Research and Environmental Intervention. Final Report to the William T. Grant Foundation. Volume One [and] Volume Two.

    ERIC Educational Resources Information Center

    Grannis, Joseph C.; Fahs, Mary Ellen

    This report evaluates a project that studied social, physical, and academic stress in the lives of students in an inner-city intermediate school and developed interventions to reduce that stress. Over 242 students, most of whom were from low-income families and almost all of whom were black, participated in the project. The following findings are…

  17. Association of PPARγ2 gene variant Pro12Ala polymorphism with hypertension and obesity in the aboriginal Qatari population known for being consanguineous.

    PubMed

    Bener, Abdulbari; Darwish, Sarah; Al-Hamaq, Abdulla Oaa; Mohammad, Ramzi M; Yousafzai, Mohammad T

    2013-01-01

    The aim of this study was to investigate the association of the Pro12Ala polymorphism of the human peroxisome proliferator-activated receptor gamma 2 (PPARγ2) gene with hypertension and obesity in a highly consanguineous aboriginal Qatari population. A cross-sectional survey conducted from January 2011-December 2012. Primary health care clinics. A random sample of 1,528 Qatari male and female population older than 20 years of age. Data on age, sex, income, level of education, occupation status, body mass index, and blood pressure and lipid profile were obtained. The Pro12Ala in the PPARγ2 gene was detected on the LightCycler® using two specific probes: (Sensor [G] 5'-CTC CTA TTG ACG CAG AAA GCG-FL and PPAR Anchor 5' LC Red 640- TCC TTC ACT GAT ACA CTG TCT GCA AAC ATA TC-PH). Univariate and multivariate logistic regression were performed. Out of a total 1,528 participants, 220 were diagnosed with essential hypertension, and 420 were obese. Participants with consanguinity were significantly higher among hypertensive than normotensive (41.9% versus 30.8%; P=0.001). Altogether, more than three-fourths (89%) of the participants had a wild genotype (Pro12Pro), 9.8% were heterozygous with Pro12Ala, and only 1.2% was homozygous with the Ala12Ala genotype. The frequency of the Pro allele was 94.5% in normotensive versus 90.5% in hypertensive, while the distribution of the Ala allele was 5.5% in normotensive versus 9.5% in the hypertensive group (P=0.001). The odds of hypertension were 1.7 times higher among the participants with the Ala allele as compared to those with the Pro, while adjusting for other potential confounders (adjusted odds ratio 1.69; 95% confidence interval 1.12-2.55; P=0.012). There was no association between the PPARγ2Ala allele and obesity (P=0.740). The current study revealed an association between the PPARγ2Ala allele and hypertension in Qatar's population. On the other hand, this study found no association between the Ala allele and obesity.

  18. Association of PPARγ2 gene variant Pro12Ala polymorphism with hypertension and obesity in the aboriginal Qatari population known for being consanguineous

    PubMed Central

    Bener, Abdulbari; Darwish, Sarah; Al-Hamaq, Abdulla OAA; Mohammad, Ramzi M; Yousafzai, Mohammad T

    2013-01-01

    Aim The aim of this study was to investigate the association of the Pro12Ala polymorphism of the human peroxisome proliferator-activated receptor gamma 2 (PPARγ2) gene with hypertension and obesity in a highly consanguineous aboriginal Qatari population. Design A cross-sectional survey conducted from January 2011–December 2012. Setting Primary health care clinics. Subjects A random sample of 1,528 Qatari male and female population older than 20 years of age. Materials and methods Data on age, sex, income, level of education, occupation status, body mass index, and blood pressure and lipid profile were obtained. The Pro12Ala in the PPARγ2 gene was detected on the LightCycler® using two specific probes: (Sensor [G] 5′-CTC CTA TTG ACG CAG AAA GCG-FL and PPAR Anchor 5′ LC Red 640- TCC TTC ACT GAT ACA CTG TCT GCA AAC ATA TC-PH). Univariate and multivariate logistic regression were performed. Result Out of a total 1,528 participants, 220 were diagnosed with essential hypertension, and 420 were obese. Participants with consanguinity were significantly higher among hypertensive than normotensive (41.9% versus 30.8%; P=0.001). Altogether, more than three-fourths (89%) of the participants had a wild genotype (Pro12Pro), 9.8% were heterozygous with Pro12Ala, and only 1.2% was homozygous with the Ala12Ala genotype. The frequency of the Pro allele was 94.5% in normotensive versus 90.5% in hypertensive, while the distribution of the Ala allele was 5.5% in normotensive versus 9.5% in the hypertensive group (P=0.001). The odds of hypertension were 1.7 times higher among the participants with the Ala allele as compared to those with the Pro, while adjusting for other potential confounders (adjusted odds ratio 1.69; 95% confidence interval 1.12–2.55; P=0.012). There was no association between the PPARγ2Ala allele and obesity (P=0.740). Conclusion The current study revealed an association between the PPARγ2Ala allele and hypertension in Qatar’s population. On the other

  19. Diesel Mechanics. Performance Objectives. Intermediate Course.

    ERIC Educational Resources Information Center

    Tidwell, Joseph

    Several intermediate performance objectives and corresponding criterion measures are listed for each of six terminal objectives for an intermediate diesel mechanics course (two semesters, 3 hours daily) designed for high school students who upon completion would be ready for an on-the-job training experience in diesel service and repair. Through…

  20. Relationship between Perceived and Observed Student-Centred Learning Environments in Qatari Elementary Mathematics and Science Classrooms

    ERIC Educational Resources Information Center

    Knight, Stephanie L.; Parker, Dawn; Zimmerman, Whitney; Ikhlief, Atman

    2014-01-01

    Recently, Qatar established educational reform in charter (independent) schools focusing on curriculum standards, student-centred teaching, standards-based assessment, English as the language of instruction, and extensive professional development. A primary area of emphasis was the creation of student-centred mathematics and science classrooms…

  1. Relationship between Perceived and Observed Student-Centred Learning Environments in Qatari Elementary Mathematics and Science Classrooms

    ERIC Educational Resources Information Center

    Knight, Stephanie L.; Parker, Dawn; Zimmerman, Whitney; Ikhlief, Atman

    2014-01-01

    Recently, Qatar established educational reform in charter (independent) schools focusing on curriculum standards, student-centred teaching, standards-based assessment, English as the language of instruction, and extensive professional development. A primary area of emphasis was the creation of student-centred mathematics and science classrooms…

  2. The Importance of Identifying Levels in Multilevel Analysis: An Illustration of the Effects of Ignoring the Top or Intermediate Levels in school Effectiveness Research.

    ERIC Educational Resources Information Center

    Opdenakker, Marie-Christine; van Damme, Jan

    2000-01-01

    Explores effects of ignoring one or more levels of variation in hierarchical linear regression analysis, using a model with four hierarchical levels. Ignoring the top or intermediate levels influences fixed coefficients, variance components, and their corresponding standard error and can lead to different research conclusions. (Contains 16…

  3. Master Curriculum Guide in Economics for the Nation's Schools. Part II, Strategies for Teaching Economics. Intermediate Level (Grades 4-6).

    ERIC Educational Resources Information Center

    Joint Council on Economic Education, New York, NY.

    This guide contains concept based lessons and activities in economics for use with students in grades 4-6. One component of a two-part publication, the guide demonstrates how the conceptual structure of the economics discipline presented in the first publication (ED 148 648) can be used to help students at the intermediate grade level make more…

  4. Establishing the Intermediate Unit.

    ERIC Educational Resources Information Center

    Pennsylvania State Dept. of Education, Harrisburg.

    The State of Pennsylvania Act 102 establishes a system of 29 intermediate units, creates intermediate unit boards of directors, spells out their duties and functions, and provides a system of financing their operations. This handbook has been prepared by the Pennsylvania Department of Education to provide intermediate unit boards of directors,…

  5. Reading Resource Manual for Intermediate Grade Levels.

    ERIC Educational Resources Information Center

    Conforti, Diane; Feeley, Dot

    This guide describes where specific skills are emphasized in the three reading texts (published by Ginn, Holt, and Lyons and Carnhan) used in the intermediate grades in the Stoneham (Massachusetts) Public School System. The four major sections of the book are color-coded and include phonetic and structural analysis, vocabulary development, study…

  6. Measuring. USMES Intermediate "How To" Set.

    ERIC Educational Resources Information Center

    Agro, Sally; And Others

    In this set of five booklets on measuring, intermediate grade students learn how to use a stopwatch, choose the right tool to measure distance, use a trundle wheel, make a scale drawing, and find the speed of things. The major emphasis in all Unified Sciences and Mathematics for Elementary Schools (USMES) units is on open-ended, long-range…

  7. The Intermediate Unit as a Change Agent.

    ERIC Educational Resources Information Center

    Stout, Jerry B.

    Major benefits are to be derived from the establishment of a middle echelon agency functioning as a link between the State department of education and local school districts. Such an intermediate unit is the ideal agency not only to provide services in high cost, low pupil incidence areas, but also to be the needed change agent for education. It…

  8. Law Enforcement Careers. Performance Objectives. Intermediate Course.

    ERIC Educational Resources Information Center

    Adams, John F.S.

    Intermediate performance objectives and corresponding criterion measures are presented for each of six terminal objectives for a two-semester (3 hours daily) course designed to provide high school juniors and seniors with basic law enforcement skills and knowledge. Titles of the six terminal objectives are State Criminal Code, Patrol Methods and…

  9. Teaching about "Intermediate Forms."

    ERIC Educational Resources Information Center

    Hazard, Evan B.

    1998-01-01

    Argues that the common assumption about the lack of intermediate forms in evolutionary history is inaccurate and misleading. Points out that there are many transitional forms, although special creationists refuse to recognize them as such. (DDR)

  10. Machine Shop. Performance Objectives. Intermediate Course. Career Education.

    ERIC Educational Resources Information Center

    Hilton, Arthur; Lambert, George

    Several intermediate performance objectives and corresponding criterion measures are listed for each of eight terminal objectives for a high school intermediate machine shop course. The materials were developed for a 36-week course (3 hours daily) designed to enable students to become familiar with the operation of machine shop equipment, to…

  11. Commercial and Advertising Art. Performance Objectives. Intermediate Course.

    ERIC Educational Resources Information Center

    Atkinson, Floyd

    Several intermediate performance objectives and corresponding criterion measures are listed for each of eight terminal objectives for an intermediate commercial and advertising art course for high school vocational students. The materials were developed for a two-semester (3 hours daily) course involving specialized classroom, shop, and practical…

  12. Commercial and Advertising Art. Performance Objectives. Intermediate Course.

    ERIC Educational Resources Information Center

    Atkinson, Floyd

    Several intermediate performance objectives and corresponding criterion measures are listed for each of eight terminal objectives for an intermediate commercial and advertising art course for high school vocational students. The materials were developed for a two-semester (3 hours daily) course involving specialized classroom, shop, and practical…

  13. MATERIALS FOR INTERMEDIATE TELUGU.

    ERIC Educational Resources Information Center

    KELLEY, GERALD B.

    ONE OF THE FOUR DRAVIDIAN LANGUAGES RECOGNIZED BY THE INDIAN CONSTITUTION OF 1950 AS OFFICIAL LANGUAGES OF THE COUNTRY, TELUGU IS SPOKEN BY 42 MILLION PEOPLE IN ANDHRA PRADESH. THESE INSTRUCTIONAL MATERIALS ARE DESIGNED FOR THE INTERMEDIATE STUDENT OF TELUGU AND ARE DIVIDED INTO NEWSPAPER READINGS AND DIALOGUES OF EVERYDAY CONVERSATION. SUBJECTS…

  14. SPACE: Intermediate Level Modules.

    ERIC Educational Resources Information Center

    Indiana State Dept. of Education, Indianapolis. Center for School Improvement and Performance.

    These modules were developed to assist teachers at the intermediate level to move away from extensive skill practice and toward more meaningful interdisciplinary learning. This packet, to be used by teachers in the summer Extended Learning Program, provides detailed thematic lesson plans matched to the Indiana Curriculum Proficiency Guide. The…

  15. MATERIALS FOR INTERMEDIATE TELUGU.

    ERIC Educational Resources Information Center

    KELLEY, GERALD B.

    ONE OF THE FOUR DRAVIDIAN LANGUAGES RECOGNIZED BY THE INDIAN CONSTITUTION OF 1950 AS OFFICIAL LANGUAGES OF THE COUNTRY, TELUGU IS SPOKEN BY 42 MILLION PEOPLE IN ANDHRA PRADESH. THESE INSTRUCTIONAL MATERIALS ARE DESIGNED FOR THE INTERMEDIATE STUDENT OF TELUGU AND ARE DIVIDED INTO NEWSPAPER READINGS AND DIALOGUES OF EVERYDAY CONVERSATION. SUBJECTS…

  16. SPACE: Intermediate Level Modules.

    ERIC Educational Resources Information Center

    Indiana State Dept. of Education, Indianapolis. Center for School Improvement and Performance.

    These modules were developed to assist teachers at the intermediate level to move away from extensive skill practice and toward more meaningful interdisciplinary learning. This packet, to be used by teachers in the summer Extended Learning Program, provides detailed thematic lesson plans matched to the Indiana Curriculum Proficiency Guide. The…

  17. Sara Intermediate Course.

    ERIC Educational Resources Information Center

    Thayer, James E.; Maraby, Julien

    This volume consists of an intermediate course in Sara, a language of the Chad Republic of Africa. It is designed for native speakers of English and includes forty reading selections in Sara and an English translation of each selection. The readings are followed by a corresponding set of dialogues in Sara, accompanied by an English translation.…

  18. Intermediate Pashto. Textbook.

    ERIC Educational Resources Information Center

    Tegey, Habibullah; Robson, Barbara

    The textbook for intermediate level Pashto instruction consists of 14 units (15-28) on a variety of cultural topics and linguistic structures. Cultural topics include engagement and marriage, children's education, agriculture and related subjects, the family, Pashtun history, genealogies of major Pashtun tribes, the Pashtun code of behavior,…

  19. The Intermediate Neutrino Program

    SciTech Connect

    Adams, C.; et al.

    2015-03-23

    The US neutrino community gathered at the Workshop on the Intermediate Neutrino Program (WINP) at Brookhaven National Laboratory February 4-6, 2015 to explore opportunities in neutrino physics over the next five to ten years. Scientists from particle, astroparticle and nuclear physics participated in the workshop. The workshop examined promising opportunities for neutrino physics in the intermediate term, including possible new small to mid-scale experiments, US contributions to large experiments, upgrades to existing experiments, R&D plans and theory. The workshop was organized into two sets of parallel working group sessions, divided by physics topics and technology. Physics working groups covered topics on Sterile Neutrinos, Neutrino Mixing, Neutrino Interactions, Neutrino Properties and Astrophysical Neutrinos. Technology sessions were organized into Theory, Short-Baseline Accelerator Neutrinos, Reactor Neutrinos, Detector R&D and Source, Cyclotron and Meson Decay at Rest sessions.This report summarizes discussion and conclusions from the workshop.

  20. Intermediate water recovery system

    NASA Technical Reports Server (NTRS)

    Deckman, G.; Anderson, A. R. (Editor)

    1973-01-01

    A water recovery system for collecting, storing, and processing urine, wash water, and humidity condensates from a crew of three aboard a spacecraft is described. The results of a 30-day test performed on a breadboard system are presented. The intermediate water recovery system produced clear, sterile, water with a 96.4 percent recovery rate from the processed urine. Recommendations for improving the system are included.

  1. Modeling DNA Replication Intermediates

    SciTech Connect

    Broyde, S.; Roy, D.; Shapiro, R.

    1997-06-01

    While there is now available a great deal of information on double stranded DNA from X-ray crystallography, high resolution NMR and computer modeling, very little is known about structures that are representative of the DNA core of replication intermediates. DNA replication occurs at a single strand/double strand junction and bulged out intermediates near the junction can lead to frameshift mutations. The single stranded domains are particularly challenging. Our interest is focused on strategies for modeling the DNA of these types of replication intermediates. Modeling such structures presents special problems in addressing the multiple minimum problem and in treating the electrostatic component of the force field. We are testing a number of search strategies for locating low energy structures of these types and we are also investigating two different distance dependent dielectric functions in the coulombic term of the force field. We are studying both unmodified DNA and DNA damaged by aromatic amines, carcinogens present in the environment in tobacco smoke, barbecued meats and automobile exhaust. The nature of the structure adopted by the carcinogen modified DNA at the replication fork plays a key role in determining whether the carcinogen will cause a mutation during replication that can initiate the carcinogenic process. In the present work results are presented for unmodified DNA.

  2. Environmental Education, Intermediate Division, Boalsburg School.

    ERIC Educational Resources Information Center

    State College Area School District, PA.

    Presented is an eight-week environmental education unit for third- and fourth-grade students. Three major concepts are developed: Independence, survival adaptation, and recyclement. Each concept is used to construct a section of activities that contribute to the student's development of that concept. A large appendix section lists many additional…

  3. Discoveries: Fiction for Intermediate School Years.

    ERIC Educational Resources Information Center

    Library of Congress, Washington, DC. National Library Service for the Blind and Physically Handicapped.

    This bibliography of selected fiction books is designed to reinforce creative growth, expand experience, and promote understanding and personal development for visually or physically disabled students between grade 4 and grade 6. All the books listed are available on disc, on cassette, or in braille in network library collections provided by the…

  4. Computer Literacy: Intermediate and Secondary Grades, Second Edition.

    ERIC Educational Resources Information Center

    New York City Board of Education, Brooklyn, NY.

    This curriculum guide outlines a course on computer literacy for junior or senior high school students reflecting the technology of the early 1980s. A chart shows computer literacy scope and sequence for students in kindergarten, grades 1-2, grades 3-6, and grades 7-9. Forty lessons for the intermediate grades and high school are then presented,…

  5. Computer Literacy: Intermediate and Secondary Grades, Second Edition.

    ERIC Educational Resources Information Center

    New York City Board of Education, Brooklyn, NY.

    This curriculum guide outlines a course on computer literacy for junior or senior high school students reflecting the technology of the early 1980s. A chart shows computer literacy scope and sequence for students in kindergarten, grades 1-2, grades 3-6, and grades 7-9. Forty lessons for the intermediate grades and high school are then presented,…

  6. Heterophobia: Subverting Heterosexual Hegemony through Intermedial Applied Performance for Young People

    ERIC Educational Resources Information Center

    Phillips, Hannah

    2016-01-01

    This article responds to intermediality through a case study of an intermedial applied performance for young people. "Heterophobia," a hybrid fusion of live performance, digital technology, social media and urban street art, aimed to challenge homophobia in schools and online. Intermediality was used as a tool to enhance young people's…

  7. Heterophobia: Subverting Heterosexual Hegemony through Intermedial Applied Performance for Young People

    ERIC Educational Resources Information Center

    Phillips, Hannah

    2016-01-01

    This article responds to intermediality through a case study of an intermedial applied performance for young people. "Heterophobia," a hybrid fusion of live performance, digital technology, social media and urban street art, aimed to challenge homophobia in schools and online. Intermediality was used as a tool to enhance young people's…

  8. Intermediate inputs and economic productivity.

    PubMed

    Baptist, Simon; Hepburn, Cameron

    2013-03-13

    Many models of economic growth exclude materials, energy and other intermediate inputs from the production function. Growing environmental pressures and resource prices suggest that this may be increasingly inappropriate. This paper explores the relationship between intermediate input intensity, productivity and national accounts using a panel dataset of manufacturing subsectors in the USA over 47 years. The first contribution is to identify sectoral production functions that incorporate intermediate inputs, while allowing for heterogeneity in both technology and productivity. The second contribution is that the paper finds a negative correlation between intermediate input intensity and total factor productivity (TFP)--sectors that are less intensive in their use of intermediate inputs have higher productivity. This finding is replicated at the firm level. We propose tentative hypotheses to explain this association, but testing and further disaggregation of intermediate inputs is left for further work. Further work could also explore more directly the relationship between material inputs and economic growth--given the high proportion of materials in intermediate inputs, the results in this paper are suggestive of further work on material efficiency. Depending upon the nature of the mechanism linking a reduction in intermediate input intensity to an increase in TFP, the implications could be significant. A third contribution is to suggest that an empirical bias in productivity, as measured in national accounts, may arise due to the exclusion of intermediate inputs. Current conventions of measuring productivity in national accounts may overstate the productivity of resource-intensive sectors relative to other sectors.

  9. [Intermediate endpoints in clinical research].

    PubMed

    Peters, Sanne A E; Groenwold, Rolf H H; Bots, Michiel L

    2013-01-01

    An intermediate variable such as blood pressure is part of the causal pathway of mechanisms to a clinical outcome, e.g. myocardial infarction. An intervention affects a clinical outcome through its effect on that intermediate variable. In studies designed to assess the effects of interventions an intermediate variable may be used as surrogate for clinical outcomes. Such an endpoint is also known as an intermediate endpoint. Intervention studies with intermediate endpoints are commonly performed in medical research to evaluate the effects of an intervention on clinical outcomes. Intervention studies with an intermediate endpoint are conducted in a smaller study population and with a shorter duration of follow-up than studies using clinical outcomes. An intermediate variable is not eligible as an intermediate endpoint when the intervention also affects other biological mechanisms that subsequently affect the clinical endpoint. Due to a smaller sample size and shorter study duration, side effects of intervention are more difficult to evaluate in studies with an intermediate endpoint than in studies with clinical endpoints.

  10. Intermediate BL Lac objects

    NASA Astrophysics Data System (ADS)

    Bondi, M.; Marchã, M. J. M.; Dallacasa, D.; Stanghellini, C.

    2001-08-01

    The 200-mJy sample, defined by Marchã et al., contains about 60 nearby, northern, flat-spectrum radio sources. In particular, the sample has proved effective at finding nearby radio-selected BL Lac objects with radio luminosities comparable to those of X-ray-selected objects, and low-luminosity flat-spectrum weak emission-line radio galaxies (WLRGs). The 200-mJy sample contains 23 BL Lac objects (including 6 BL Lac candidates) and 19 WLRGs. We will refer to these subsamples as the 200-mJy BL Lac sample and the 200-mJy WLRG sample, respectively. We have started a systematic analysis of the morphological pc-scale properties of the 200-mJy radio sources using VLBI observations. This paper presents VLBI observations at 5 and 1.6GHz of 14 BL Lac objects and WLRGs selected from the 200-mJy sample. The pc-scale morphology of these objects is briefly discussed. We derive the radio beaming parameters of the 200-mJy BL Lac objects and WLRGs and compare them with those of other BL Lac samples and with a sample of FR I radio galaxies. The overall broad-band radio, optical and X-ray properties of the 200-mJy BL Lac sample are discussed and compared with those of other BL Lac samples, radio- and X-ray-selected. We find that the 200-mJy BL Lac objects fill the gap between HBL and LBL objects in the colour-colour plot, and have intermediate αXOX as expected in the spectral energy distribution unification scenario. Finally, we briefly discuss the role of the WLRGs.

  11. Printing. Performance Objectives. Intermediate Course.

    ERIC Educational Resources Information Center

    Seivert, Chester

    Several intermediate performance objectives and corresponding criterion measures are listed for each of 13 terminal objectives for an intermediate printing course. The materials were developed for a two-semester (3 hours daily) course with specialized classroom, shop, and practical experiences designed to enable the student to develop proficiency…

  12. Masonry. Performance Objectives. Intermediate Course.

    ERIC Educational Resources Information Center

    Thompson, Moses

    Several intermediate performance objectives and corresponding criterion measures are listed for each of 13 terminal objectives for an intermediate masonry course. These materials, developed for a two-semester (3 hours daily) course, are designed to provide the student with the skills and knowledge necessary for entry level employment in the field…

  13. Welding. Performance Objectives. Intermediate Course.

    ERIC Educational Resources Information Center

    Vincent, Kenneth

    Several intermediate performance objectives and corresponding criterion measures are listed for each of nine terminal objectives for an intermediate welding course. The materials were developed for a 36-week (3 hours daily) course designed to prepare the student for employment in the field of welding. Electric welding and specialized (TIG & MIG)…

  14. Printing. Performance Objectives. Intermediate Course.

    ERIC Educational Resources Information Center

    Seivert, Chester

    Several intermediate performance objectives and corresponding criterion measures are listed for each of 13 terminal objectives for an intermediate printing course. The materials were developed for a two-semester (3 hours daily) course with specialized classroom, shop, and practical experiences designed to enable the student to develop proficiency…

  15. Intermediate dosimetric quantities.

    PubMed

    Kellerer, A M; Hahn, K; Rossi, H H

    1992-04-01

    The transfer of energy from ionizing radiation to matter involves a series of steps. In wide ranges of their energy spectra photons and neutrons transfer energy to an irradiated medium almost exclusively by the production of charged particles which ionize and thereby produce electrons that can ionize in turn. The examination of these processes leads to a series of intermediate quantities. One of these is kerma, which has long been employed as a measure of the energy imparted in the first of the interactions. It depends only on the fluence of uncharged particles and is therefore--unlike absorbed dose and electron fluence--insensitive to local differences of receptor geometry and composition. An analogous quantity for charged-particle fields, cema (converted energy per unit mass), is defined, which quantifies the energy imparted in terms of the interactions of charged particles, disregarding energy dissipation by secondary electrons. Cema can be expressed as an integral over the fluence of ions times their stopping power. However, complications arise when the charged particles are electrons, and when their fluence cannot be separated from that of the secondaries. The resulting difficulty can be circumvented by the definition of reduced cema. This quantity corresponds largely to the concept employed in the cavity theory of Spencer and Attix. In reduced cema not all secondary electrons but all electrons below a chosen cutoff energy, delta, are considered to be absorbed locally. When the cutoff energy is reduced, cema approaches absorbed dose and thereby becomes sensitive to highly local differences in geometry or composition. With larger values of delta, reduced cema is a useful parameter to specify the dose-generating potential of a charged-particle field 'free in air' or in vacuo. It is nearly equal to the mean absorbed dose in a sphere with radius equal to the range of electrons of energy delta. Reduced cema is a function of the fluence at the specified location at

  16. Intermediate-statistics spin waves

    NASA Astrophysics Data System (ADS)

    Dai, Wu-Sheng; Xie, Mi

    2009-04-01

    In this paper, we show that spin waves, the elementary excitation of the Heisenberg magnetic system, obey a kind of intermediate statistics with a finite maximum occupation number n. We construct an operator realization for the intermediate statistics obeyed by magnons, the quantized spin waves, and then construct a corresponding intermediate-statistics realization for the angular momentum algebra in terms of the creation and annihilation operators of the magnons. In other words, instead of the Holstein-Primakoff representation, a bosonic representation subject to a constraint on the occupation number, we present an intermediate-statistics representation with no constraints. In this realization, the maximum occupation number is naturally embodied in the commutation relation of creation and annihilation operators, while the Holstein-Primakoff representation is a bosonic operator relation with an additional putting-in-by-hand restriction on the occupation number. We deduce the intermediate-statistics distribution function for magnons from the intermediate-statistics commutation relation of the creation and annihilation operators directly, which is a modified Bose-Einstein distribution. On the basis of these results, we calculate the dispersion relations for ferromagnetic and antiferromagnetic spin waves. The relations between the intermediate statistics that magnons obey and the other two important kinds of intermediate statistics, Haldane-Wu statistics and the fractional statistics of anyons, are discussed. We also compare the spectrum of the intermediate-statistics spin wave with the exact solution of the one-dimensional s = 1/2 Heisenberg model, which is obtained by the Bethe ansatz method. For ferromagnets, we take the contributions from the interaction between magnons (the quartic contribution), the next-to-nearest-neighbor interaction, and the dipolar interaction into account for comparison with the experiment.

  17. On the Use of Writing Assignments in Intermediate Microeconomic Theory

    ERIC Educational Resources Information Center

    O'Neill, Patrick B.

    2009-01-01

    A typical writing assignment in upper level required courses is a term paper. However many economics majors, particularly those in business schools, need to develop skill at writing shorter pieces. In this paper I describe numerous examples of shorter writing assignments that I have incorporated into an Intermediate Microeconomic Theory course.…

  18. TLC for Growing Minds. Microcomputer Projects. Elementary Intermediate Microcomputer Projects.

    ERIC Educational Resources Information Center

    Buxton, Marilyn

    Designed to improve students' thinking, learning, and creative skills while they learn to program a microcomputer in BASIC programing language, this book for intermediate learners at the elementary school level provides a variety of microcomputer activities designed to extend the concepts learned in accompanying instructional manuals (Volumes 3…

  19. Curriculum Guide for Intermediate Band--First Year.

    ERIC Educational Resources Information Center

    Bazar, W. Gayre

    This program for intermediate band classes in the Vermilion Parish Schools bridges the gap between the beginning stages of instrumental music and the advanced level of performance. Grade levels are 6 through 9. In this guide, written by teachers, administrators, and supervisors, suggestions are given for scheduling, band method books, concert…

  20. Tachyon field in intermediate inflation

    SciTech Connect

    Campo, Sergio del; Herrera, Ramon; Toloza, Adolfo

    2009-04-15

    The tachyonic inflationary universe model in the context of intermediate inflation is studied. General conditions for this model to be realizable are discussed. In the slow-roll approximation, we describe in great detail the characteristics of this model.

  1. Intermediate care for older people.

    PubMed

    Logan, Pip; Stoner-Hobbs, Val; McCloughry, Helen; Foster, Carol; Fitzsimmons, Dwane; Williams, Jo; Spencer, Pamela; Robertson, Kate; Gladman, John

    2007-06-01

    Up to 40 per cent of older people do not go to hospital after calling an emergency ambulance and until recently were not referred on to any other community services. This article describes how a multidisciplinary working group developed and evaluated a protocol to enable older people to be referred to intermediate care services after calling an emergency ambulance. A total of 54 patients were monitored after referral to intermediate care to assess adherence to the protocol and outcomes.

  2. An Evaluation of the Second Intermediate Saudi English Language Textbook from the Teachers' Point of View

    ERIC Educational Resources Information Center

    BinObaid, Reem

    2016-01-01

    The study evaluates the quality of the second intermediate grade English language textbook for Saudi girls' schools "from the teachers point of view" which was introduced at the intermediate stage by the Ministry of Education in 2004. This research project evaluates a new textbook that is considered to be the foundation stone in the…

  3. Reactions of stabilized Criegee Intermediates

    NASA Astrophysics Data System (ADS)

    Vereecken, Luc; Harder, Hartwig; Novelli, Anna

    2014-05-01

    Carbonyl oxides (Criegee intermediates) were proposed as key intermediates in the gas phase ozonolysis of alkenes in 1975 by Rudolf Criegee. Despite the importance of ozonolysis in atmospheric chemistry, direct observation of these intermediates remained elusive, with only indirect experimental evidence for their role in the oxidation of hydrocarbons, e.g. through scavenging experiments. Direct experimental observation of stabilized CI has only been achieved since 2008. Since then, a concerted effort using experimental and theoretical means is in motion to characterize the chemistry and kinetics of these reactive intermediates. We present the results of theoretical investigations of the chemistry of Criegee intermediates with a series of coreactants which may be of importance in the atmosphere, in experimental setups, or both. This includes the CI+CI cross-reaction, which proceeds with a rate coefficient near the collision limit and can be important in experimental conditions. The CI + alkene reactions show strong dependence of the rate coefficient depending on the coreactants, but is generally found to be rather slow. The CI + ozone reaction is sufficiently fast to occur both in experiment and the free troposphere, and acts as a sink for CI. The reaction of CI with hydroperoxides, ROOH, is complex, and leads both to the formation of oligomers, as to the formation of reactive etheroxides, with a moderately fast rate coefficient. The importance of these reactions is placed in the context of the reaction conditions in different atmospheric environments ranging from unpolluted to highly polluted.

  4. The Great School Swap.

    ERIC Educational Resources Information Center

    Chesto, Jon

    1997-01-01

    Examines how the New Milford (Connecticut) School District avoided failing accreditation by creating a plan to convert the deteriorating high school building into an intermediate school for grades four to six. Planning concerns and accomplishments are discussed, including overcoming parental objections, the importance of the cafeteria's location,…

  5. Intermediate tax sanctions: an overview.

    PubMed

    Peregrine, M W

    1997-07-01

    New federal tax law applies intermediate tax sanctions when tax-exempt organizations enter into so-called excess benefit transactions with corporate insiders. The sanctions take the form of a two-tiered penalty excise tax, which is assessed not on the tax-exempt organization itself but on the insider who receives the excess benefit and the organizational managers and board members who knowingly participate in an improper transaction. The intermediate tax sanctions, therefore, present tax-planning challenges for tax-exempt hospitals and integrated delivery systems as well as for 501(c)(4) HMOs. Forthcoming treasury regulations are expected to add clarity to the new law.

  6. Compact intermediates in RNA folding

    SciTech Connect

    Woodson, S.A.

    2011-12-14

    Large noncoding RNAs fold into their biologically functional structures via compact yet disordered intermediates, which couple the stable secondary structure of the RNA with the emerging tertiary fold. The specificity of the collapse transition, which coincides with the assembly of helical domains, depends on RNA sequence and counterions. It determines the specificity of the folding pathways and the magnitude of the free energy barriers to the ensuing search for the native conformation. By coupling helix assembly with nascent tertiary interactions, compact folding intermediates in RNA also play a crucial role in ligand binding and RNA-protein recognition.

  7. Intermediate and Definitive Cleft Rhinoplasty.

    PubMed

    Gary, Celeste; Sykes, Jonathan M

    2016-11-01

    Intermediate and definitive cleft rhinoplasties are a challenging part of definitive cleft care. The anatomy of the cleft nose is severely affected by the structural deficits associated with congenital orofacial clefting. A comprehensive understanding of the related anatomy is crucial for understanding how to improve the appearance and function in patients with secondary cleft nasal deformities. Timing of intermediate and definitive rhinoplasty should be carefully considered. A thorough understanding of advanced rhinoplasty techniques is an important part of providing adequate care for patients with these deformities.

  8. Mi Quinto Libro de Maquinas Simples: El Plano Inclinado. Escuela Intermedia Grados 7, 8 y 9 (My Fifth Book of Simple Machines: The Inclined Plane. Intermediate School Grades 7, 8, and 9).

    ERIC Educational Resources Information Center

    Alvarado, Patricio R.; Montalvo, Luis

    This is the fifth book in a five-book physical science series on simple machines. The books are designed for Spanish-speaking junior high school students. This volume explains the principles and some of the uses of inclined planes, as they appear in simple machines, by suggesting experiments and posing questions concerning drawings in the book…

  9. Mi Cuarto Libro de Maquinas Simples: Otras Modificaciones de la Rueda. Escuela Intermedia Grados 7, 8 y 9 (My Fourth Book of Simple Machines: Other Modifications of the Wheel. Intermediate School Grades 7, 8, and 9).

    ERIC Educational Resources Information Center

    Alvarado, Patricio R.; Montalvo, Luis

    This is the fourth book in a five-book physical science series on simple machines. The books are designed for Spanish-speaking junior high school students. This volume explains further refinements of the wheel which is introduced in volume three. The fourth volume explains principles behind gears and the relationship between velocity and force by…

  10. Mi Tercer Libro de Maquinas Simples: La Rueda y la Polea. Escuela Intermedia Grados 7, 8 y 9 (My Third Book of Simple Machines: The Wheel and the Pulley. Intermediate School Grades 7, 8, and 9).

    ERIC Educational Resources Information Center

    Alvarado, Patricio R.; Montalvo, Luis

    This is the third book in a five-book physical science series on simple machines. The books are designed for Spanish-speaking junior high school students. This volume explains principles governing wheels and pulleys by suggesting experiments and posing questions concerning drawings in the book which illustrate the scientific principles. Friction…

  11. Mi Primer Libro de Maquinas Simples: Trabajo y Fuerza. Escuela Intermedia Grados 7, 8 y 9 (My First Book of Simple Machines: Work and Force. Intermediate School Grades 7, 8, and 9).

    ERIC Educational Resources Information Center

    Alvarado, Patricio R.; Montalvo, Luis

    This is the first book in a five-book physical science series on simple machines. The books are designed for Spanish-speaking junior high school students. This volume defines force and work by suggesting experiments and posing questions concerning drawings in the book which illustrate scientific principles. Answers to the questions are provided;…

  12. Mi Segundo Libro de Maquinas Simples: Las Palancas. Escuela Intermedia Grados 7, 8 y 9 (My Second Book of Simple Machines: Levers. Intermediate School Grades 7, 8, and 9).

    ERIC Educational Resources Information Center

    Alvarado, Patricio R.; Montalvo, Luis

    This is the second book in a five-book physical science series on simple machines. The books are designed for Spanish-speaking junior high school students. By suggesting experiments and posing questions concerning drawings in the book which illustrate the scientific principles, this book explains the workings of three types of levers. Resistance…

  13. Conversation at the Intermediate Level

    ERIC Educational Resources Information Center

    Dunlop, Ian

    1975-01-01

    Discusses the use of free conversation, especially with regard to vocabulary. Recommends group discussion in the FL, using, at the intermediate level, limited, familiar vocabulary. At a higher level, words from a special technical vocabulary may be introduced, aurally and visually. A teaching example ("Traffic") is given with thorough…

  14. AIDS Elementary/Intermediate Curriculum.

    ERIC Educational Resources Information Center

    Kellogg, Nancy Rader

    This Acquired Immune Deficiency Syndrome (AIDS) Curriculum was developed for intermediate elementary (5th, 6th, and 7th grade) students. It is an integrated unit that encompasses health, science, social studies, math, and language arts. The curriculum is comprised of nine class activities designed to meet the following objectives: (1) to determine…

  15. Material Voices: Intermediality and Autism

    ERIC Educational Resources Information Center

    Trimingham, Melissa; Shaughnessy, Nicola

    2016-01-01

    Autism continues to be regarded enigmatically; a community that is difficult to access due to perceived disruptions of interpersonal connectedness. Through detailed observations of two children participating in the Arts and Humanities Research Council funded project "Imagining Autism: Drama, Performance and Intermediality as Interventions for…

  16. Learning through Literature: Geography, Intermediate.

    ERIC Educational Resources Information Center

    Sterling, Mary Ellen

    This resource book provides specific strategies and activities for integrating the intermediate geography curriculum with related children's literature selections. The book includes the following sections: (1) "World Geography Overview"; (2) "Oceans"; (3) "Polar Regions"; (4) "Islands"; (5) "Rain Forests"; (6) "Mountains"; (7) "Forests"; (8)…

  17. Intermediality and the Child Performer

    ERIC Educational Resources Information Center

    Budd, Natasha

    2016-01-01

    This report details examples of praxis in the creation and presentation of "Joy Fear and Poetry": an intermedial theatre performance in which children aged 7-12 years generated aesthetic gestures using a range of new media forms. The impetus for the work's development was a desire to make an intervention into habituated patterns of…

  18. Material Voices: Intermediality and Autism

    ERIC Educational Resources Information Center

    Trimingham, Melissa; Shaughnessy, Nicola

    2016-01-01

    Autism continues to be regarded enigmatically; a community that is difficult to access due to perceived disruptions of interpersonal connectedness. Through detailed observations of two children participating in the Arts and Humanities Research Council funded project "Imagining Autism: Drama, Performance and Intermediality as Interventions for…

  19. Learning through Literature: Geography, Intermediate.

    ERIC Educational Resources Information Center

    Sterling, Mary Ellen

    This resource book provides specific strategies and activities for integrating the intermediate geography curriculum with related children's literature selections. The book includes the following sections: (1) "World Geography Overview"; (2) "Oceans"; (3) "Polar Regions"; (4) "Islands"; (5) "Rain Forests"; (6) "Mountains"; (7) "Forests"; (8)…

  20. Intermediality and the Child Performer

    ERIC Educational Resources Information Center

    Budd, Natasha

    2016-01-01

    This report details examples of praxis in the creation and presentation of "Joy Fear and Poetry": an intermedial theatre performance in which children aged 7-12 years generated aesthetic gestures using a range of new media forms. The impetus for the work's development was a desire to make an intervention into habituated patterns of…

  1. Partners to invite bids for Qatari plant

    SciTech Connect

    Alperowicz, N.

    1994-05-18

    Qasenco, a joint venture planning to build a methanol plant at Umm Said, Qatar, will issue prequalification documents to contractors in early July. Partnership agreements to form the joint venture are expected to be concluded at the beginning of June. Qatar General Petroleum Corp. (Doha) will hold 50%. The remaining share will be split between Petronas (Kuala Lumpur) and Penspen (London). Other shareholders may also join. Market studies for the 2,500-m.t./day plant were based on ICI`s technology, but the partners want to look at other available processes-including Mitsubishi Gas Chemical`s-before committing to the $400-million venture. Schroder Wagg (London) has been appointed as the project`s financial adviser. About 30% of the financing is expected to come from equity and the rest as longterm credit. Petronas, the Malaysian state-owned energy company, already owns a 2,000-m.t./day methanol plant at Labuan but needs more product for its customers in the Far East. The company is interested in taking at least 50% of the output from the Umm Said plant.

  2. Hot Topics in School Public Relations.

    ERIC Educational Resources Information Center

    Lange, Lois, Ed.; Young, Jay, Ed.

    This document examines the public relations activities occurring in K-12 and intermediate school districts, needs for other activities, and how Michigan School Public Relations Association (MSPRA) can assist. Written surveys were mailed to 394 K-12 and Intermediate School District (ISD) superintendents. Analysis showed that very few school…

  3. Mechanics of vimentin intermediate filaments

    NASA Technical Reports Server (NTRS)

    Wang, Ning; Stamenovic, Dimitrijie

    2002-01-01

    It is increasingly evident that the cytoskeleton of living cells plays important roles in mechanical and biological functions of the cells. Here we focus on the contribution of intermediate filaments (IFs) to the mechanical behaviors of living cells. Vimentin, a major structural component of IFs in many cell types, is shown to play an important role in vital mechanical and biological functions such as cell contractility, migration, stiffness, stiffening, and proliferation.

  4. PERIPHERAL RETINOSCHISIS IN INTERMEDIATE UVEITIS.

    PubMed

    Pichi, Francesco; Srivastava, Sunil K; Nucci, Paolo; Baynes, Kimberly; Neri, Piergiorgio; Lowder, Careen Y

    2017-01-11

    To examine cases of intermediate uveitis complicated by retinoschisis and review the pathogenetic hypothesis. A retrospective chart review of patients with intermediate uveitis. Data were collected at three uveitis referral centers on sex, age, best-corrected visual acuity, degree of vitritis, extent and location of snowbanking, presence of hard exudates, neovascularization, vitreous hemorrhage, and extent and nature of retinal elevations. A series of 23 eyes of 20 patients were examined; patient's age ranged from 10 years to 70 years and follow-up period from 8 months to 6 years. Twenty-two eyes had retinoschisis (95.6%), and 1 had retinoschisis associated with serous retinal detachment (4.3%). Extensive inferior pars plana exudates with snowbanking were present in 12 eyes (52.2%), whereas 3 eyes had inferior snowballs over the elevated retina. Neovascularization of the vitreous base accompanied by vitreous hemorrhage occurred in one eye. There was no coexisting macular pathology in 16 eyes, whereas 4 eyes had cystoid macular edema. The appearance of peripheral retinoschisis in this series of uncontrolled intermediate uveitis patients seems to be secondary to a complex balance between the persistent fluorescein leakage, a subclinical peripheral ischemia, and the constant low-grade vitreous inflammation that causes vitreous shrinkage and traction. The results of this study suggest that the absence of macroscopic changes in the retina does not preclude ischemic peripheral abnormalities, and the detection of a peripheral retinoschisis in an intermediate uveitis patient with active fluorescein leakage must suggest the need for a more aggressive form of treatment despite the good visual acuity.

  5. Mechanics of vimentin intermediate filaments

    NASA Technical Reports Server (NTRS)

    Wang, Ning; Stamenovic, Dimitrijie

    2002-01-01

    It is increasingly evident that the cytoskeleton of living cells plays important roles in mechanical and biological functions of the cells. Here we focus on the contribution of intermediate filaments (IFs) to the mechanical behaviors of living cells. Vimentin, a major structural component of IFs in many cell types, is shown to play an important role in vital mechanical and biological functions such as cell contractility, migration, stiffness, stiffening, and proliferation.

  6. Branching of keratin intermediate filaments.

    PubMed

    Nafeey, Soufi; Martin, Ines; Felder, Tatiana; Walther, Paul; Felder, Edward

    2016-06-01

    Keratin intermediate filaments (IFs) are crucial to maintain mechanical stability in epithelial cells. Since little is known about the network architecture that provides this stiffness and especially about branching properties of filaments, we addressed this question with different electron microscopic (EM) methods. Using EM tomography of high pressure frozen keratinocytes, we investigated the course of several filaments in a branching of a filament bundle. Moreover we found several putative bifurcations in individual filaments. To verify our observation we also visualized the keratin network in detergent extracted keratinocytes with scanning EM. Here bifurcations of individual filaments could unambiguously be identified additionally to bundle branchings. Interestingly, identical filament bifurcations were also found in purified keratin 8/18 filaments expressed in Escherichia coli which were reassembled in vitro. This excludes that an accessory protein contributes to the branch formation. Measurements of the filament cross sectional areas showed various ratios between the three bifurcation arms. This demonstrates that intermediate filament furcation is very different from actin furcation where an entire new filament is attached to an existing filament. Instead, the architecture of intermediate filament bifurcations is less predetermined and hence consistent with the general concept of IF formation. Copyright © 2016 Elsevier Inc. All rights reserved.

  7. Planning-Programming-Budgeting System. Intermediate Unit Planning Study. Final Report.

    ERIC Educational Resources Information Center

    Montgomery County School Board, Norristown, PA.

    In 1965-66 most local school districts in Pennsylvania completed reorganization by consolidating 67 county school offices into 25 or 30 intermediate administrative units. This document presents the results of various task group activities and projected activities to develop a "generalized" educational planning, programing, budgeting…

  8. Increasing Constructive Behavior of Intermediate Grade Students through the Use of The Response Cost Strategy

    ERIC Educational Resources Information Center

    Bauer, Heather; Burno, Carolyn; Millstone, Teresa

    2009-01-01

    The purpose of this research project was to increase constructive behavior of intermediate grade students through the use of the response cost strategy. Approximately 70 students participated in this study. Three teacher researchers conducted the research in an elementary school and two middle schools in different counties near a major mid-western…

  9. Public Schools: Support Personnel, 2003-04.

    ERIC Educational Resources Information Center

    Wenger, Cheryl L., Comp.

    2004-01-01

    This listing contains numerical/statistical data on support personnel in Pennsylvania for 2003-04 as reported by school districts, intermediate units, area vocational-technical schools, charter schools, and consortium-operated alternative high schools that employ staff (e.g., Washington County Alternative School). Support personnel are grouped…

  10. Role of Intermediate Filaments in Vesicular Traffic

    PubMed Central

    Margiotta, Azzurra; Bucci, Cecilia

    2016-01-01

    Intermediate filaments are an important component of the cellular cytoskeleton. The first established role attributed to intermediate filaments was the mechanical support to cells. However, it is now clear that intermediate filaments have many different roles affecting a variety of other biological functions, such as the organization of microtubules and microfilaments, the regulation of nuclear structure and activity, the control of cell cycle and the regulation of signal transduction pathways. Furthermore, a number of intermediate filament proteins have been involved in the acquisition of tumorigenic properties. Over the last years, a strong involvement of intermediate filament proteins in the regulation of several aspects of intracellular trafficking has strongly emerged. Here, we review the functions of intermediate filaments proteins focusing mainly on the recent knowledge gained from the discovery that intermediate filaments associate with key proteins of the vesicular membrane transport machinery. In particular, we analyze the current understanding of the contribution of intermediate filaments to the endocytic pathway. PMID:27120621

  11. Role of physical anthropology in intermediate and secondary education.

    PubMed

    Ashmore, Pamela C

    2005-01-01

    The role of physical anthropology in precollegiate education has been limited, but has the potential to play a vital and integral role in promoting students' understanding of themselves and others. This study describes the development, implementation, and results of a program constructed on an inquiry-based learning model that introduces middle and high school students to the content of physical anthropology. Demonstrated student learning indicates that intermediate and secondary students are capable of acquiring and applying complex content about human evolution and diversity. Program findings indicate that students frequently had previous knowledge about the hominid fossil record but little information about the significance of human biological diversity. Teaching intermediate and high school students about our common evolutionary heritage and the fact that humans exhibit clinal variation were found to be both powerful and effective content material. The fact that program participants lacked previous knowledge about the relationship between human biological diversity (illustrated in this program by light and dark skin color) and the erroneous sociocultural construction of this diversity confirmed the suspicion that this content is not being addressed in precollegiate education. Traditionally, intermediate and secondary students are taught about human variation within the context of social studies, reading, communication, and fine-arts classes. This program identifies a new paradigm for teaching about human variation. Providing students with scientific knowledge about human origins and diversity provides a constructive starting point, creating a common platform and knowledge base on which to then frame discussions about cultural variation. (c) 2005 Wiley-Liss, Inc.

  12. The Effect of Form versus Meaning-Focused Tasks on the Development of Collocations among Iranian Intermediate EFL Learners

    ERIC Educational Resources Information Center

    Pishghadam, Reza; Khodadady, Ebrahim; Rad, Naeemeh Daliry

    2011-01-01

    This study attempts comprehensively to investigate the effect of form versus meaning-focused tasks on the development of collocations among Iranian Intermediate EFL learners. To this end, 65 students of Mashhad High schools in Iran were selected as the participants. A general language proficiency test of Nelson (book 2, Intermediate 200A) was used…

  13. Kinetic Intermediates in RNA Folding

    NASA Astrophysics Data System (ADS)

    Zarrinkar, Patrick P.; Williamson, James R.

    1994-08-01

    The folding pathways of large, highly structured RNA molecules are largely unexplored. Insight into both the kinetics of folding and the presence of intermediates was provided in a study of the Mg2+-induced folding of the Tetrahymena ribozyme by hybridization of complementary oligodeoxynucleotide probes. This RNA folds via a complex mechanism involving both Mg2+-dependent and Mg2+-independent steps. A hierarchical model for the folding pathway is proposed in which formation of one helical domain (P4-P6) precedes that of a second helical domain (P3-P7). The overall rate-limiting step is formation of P3-P7, and takes place with an observed rate constant of 0.72 ± 0.14 minute-1. The folding mechanism of large RNAs appears similar to that of many multidomain proteins in that formation of independently stable substructures precedes their association into the final conformation.

  14. Intermediate Filaments in Caenorhabditis elegans.

    PubMed

    Zuela, Noam; Gruenbaum, Yosef

    2016-01-01

    More than 70 different genes in humans and 12 different genes in Caenorhabditis elegans encode the superfamily of intermediate filament (IF) proteins. In C. elegans, similar to humans, these proteins are expressed in a cell- and tissue-specific manner, can assemble into heteropolymers and into 5-10nm wide filaments that account for the principal structural elements at the nuclear periphery, nucleoplasm, and cytoplasm. At least 5 of the 11 cytoplasmic IFs, as well as the nuclear IF, lamin, are essential. In this chapter, we will include a short review of our current knowledge of both cytoplasmic and nuclear IFs in C. elegans and will describe techniques used for their analyses. Copyright © 2016 Elsevier Inc. All rights reserved.

  15. INTERMEDIATE FILAMENTS IN SMOOTH MUSCLE

    PubMed Central

    Tang, Dale D.

    2008-01-01

    The intermediate filament (IF) network is one of the three cytoskeletal systems in smooth muscle. The type III IF proteins vimentin and desmin are major constituents of the network in smooth muscle cells and tissues. Lack of vimentin or desmin impairs contractile ability of various smooth muscle preparations, implying their important role for smooth muscle force development. The IF framework has long been viewed as a fixed cytostructure that solely provides mechanical integrity for the cell. However, recent studies suggest that the IF cytoskeleton is dynamic in mammalian cells in response to various external stimulation. In this review, the structure and biological properties of IF proteins in smooth muscle are summarized. The role of IF proteins in the modulation of smooth muscle force development and redistribution/translocation of signaling partners (such as p130 Crk-associated substrate, CAS) is depicted. This review also summarizes our latest understanding on how the IF network may be regulated in smooth muscle. PMID:18256275

  16. Intermediate superconductive magnetic energy storage

    SciTech Connect

    Masuda, M.; Fujino, H.; Iwamoto, M.; Murakomi, M.; Shintomi, T.; Veda, K.

    1983-05-01

    In the past decade, the superconducting magnetic energy storage (SMES) for application to peak shaving in utility has been investigated in a manner to construct the huge superconducting coil in bed rock. To confine the strong electromagnetic forces accompanied with the high magnetic field, megaton structures, no matter how they will be constructed in a liquid helium temperature, are needed. To meet such a requirement, the revolutionary idea was proposed that the superconducting coil would be constructed on the underground bed rock. Here presented is a 10 MWh unit as an intermediate SMES that is a milestone along the distant way of RandD of SMES against 1,000 - 10,000 MWh unit which advocate the replacement of the hydro-pumped station. Therefore, even if the 10 MWh unit would not function as a storage in the utility network, its design should also consider the same situation.

  17. Displays for future intermediate UAV

    NASA Astrophysics Data System (ADS)

    Desjardins, Daniel; Metzler, James; Blakesley, David; Rister, Courtney; Nuhu, Abdul-Razak

    2008-04-01

    The Dedicated Autonomous Extended Duration Airborne Long-range Utility System (DAEDALUS) is a prototype Unmanned Aerial Vehicle (UAV) that won the 2007 AFRL Commander's Challenge. The purpose of the Commander's Challenge was to find an innovative solution to urgent warfighter needs by designing a UAV with increased persistence for tactical employment of sensors and communication systems. DAEDALUS was chosen as a winning prototype by AFRL, AFMC and SECAF. Follow-on units are intended to fill an intermediate role between currently fielded Tier I and Tier II UAV's. The UAV design discussed in this paper, including sensors and displays, will enter Phase II for Rapid Prototype Development with the intent of developing the design for eventual production. This paper will discuss the DAEDALUS UAV prototype system, with particular focus on its communications, to include the infrared sensor and electro-optical camera, but also displays, specifically man-portable.

  18. Microleakage of intermediate restorative materials.

    PubMed

    Lim, K C

    1990-03-01

    This study compares the microleakage of a glass ionomer cement, Ketac Fil, used without cavity conditioning, with the established intermediate restorative materials, Cavit-W, and a reinforced zinc oxide-eugenol cement, Kalzinol. Microleakage was assessed using an electrochemical technique. At the end of 30 days, the materials tested, listed in decreasing order of microleakage, were Cavit-W, Ketac Fil inserted without cavity conditioning, Kalzinol, and the control group of Ketac Fil inserted into conditioned cavities. There was no significant difference in the microleakage observed in Ketac Fil restorations inserted without cavity conditioning and Kalzinol (p = 0.450), while the differences between the other groups were highly significant (p less than 0.001).

  19. A School Divided: One Elementary School's Response to Education Policy

    ERIC Educational Resources Information Center

    Zoch, Melody

    2017-01-01

    This article examines how one elementary school was divided into two schools--a primary and an intermediate school--because of how policies were interpreted and enacted with regard to high-stakes testing. The grades in which students took high-stakes tests were privileged in terms of receiving monetary resources and support from staff. An emphasis…

  20. A School Divided: One Elementary School's Response to Education Policy

    ERIC Educational Resources Information Center

    Zoch, Melody

    2017-01-01

    This article examines how one elementary school was divided into two schools--a primary and an intermediate school--because of how policies were interpreted and enacted with regard to high-stakes testing. The grades in which students took high-stakes tests were privileged in terms of receiving monetary resources and support from staff. An emphasis…

  1. Intermediate energy heavy ion reactions

    NASA Astrophysics Data System (ADS)

    Grégoire, C.; Tamain, B.

    The intermediate energy heavy ion induced reactions are extensively studied for several years. In this paper, we try to summarize the present knowledge. The peripheral reactions appear to be intermediate between the fragmentation and the deep inelastic regimes. Many questions remain open concerning the energy relaxation mechanisms and an eventual participant zone creation. In the case of central collisions, it has been shown that very hot nuclei can be built. The fusion limits are discussed and the very hot nuclei properties are considered. In some cases, hot spot formation or compression effects could play a role. Multifragmentation is discussed as a possible decay channel. In all these aspects, a difficult question concerns the validity of the temperature concept and more generally of collective thermodynamical variables. Such collective effects have been investigated in pion production experiments. Les réactions induites par ions lourds d'énergie intermédiaire sont très étudiées depuis quelques années. Dans cet article, nous essayons de résumer l'état actuel des connaissances. Les mécanismes mis en jeu dans les collisions périphériques sont intermédiaires entre les collisions très inélastiques et la fragmentation. La cible joue clairement un rôle déterminant et des effets importants de champ moyen demeurent. De nombreuses questions restent sans réponse comme par exemple les mécanismes de relaxation d'énergie ou l'existence d'une éventuelle zone participante. Dans le cas des collisions centrales, il a pu être montré que des noyaux très chauds sont fabriqués. Les limites au processus de fusion et les propriétés des noyaux très chauds sont discutées. Dans certains cas, des effets de compression ou de points chauds peuvent être envisagés. La multifragmentation est une voie de désexcitation possible. Une importante question concerne la validité du concept de température et plus généralement la notion de variable collective

  2. Protein vivisection reveals elusive intermediates in folding

    PubMed Central

    Zheng, Zhongzhou; Sosnick, Tobin R.

    2010-01-01

    Although most folding intermediates escape detection, their characterization is crucial to the elucidation of folding mechanisms. Here we outline a powerful strategy to populate partially unfolded intermediates: A buried aliphatic residue is substituted with a charged residue (e.g., Leu→Glu−) to destabilize and unfold a specific region of the protein. We apply this strategy to Ubiquitin, reversibly trapping a folding intermediate in which the β5 strand is unfolded. The intermediate refolds to a native-like structure upon charge neutralization under mildly acidic conditions. Characterization of the trapped intermediate using NMR and hydrogen exchange methods identifies a second folding intermediate and reveals the order and free energies of the two major folding events on the native side of the rate-limiting step. This general strategy may be combined with other methods and have broad applications in the study of protein folding and other reactions that require trapping of high energy states. PMID:20144618

  3. Experiments in intermediate energy physics

    SciTech Connect

    Dehnhard, D.

    2003-02-28

    Research in experimental nuclear physics was done from 1979 to 2002 primarily at intermediate energy facilities that provide pion, proton, and kaon beams. Particularly successful has been the work at the Los Alamos Meson Physics Facility (LAMPF) on unraveling the neutron and proton contributions to nuclear ground state and transition densities. This work was done on a wide variety of nuclei and with great detail on the carbon, oxygen, and helium isotopes. Some of the investigations involved the use of polarized targets which allowed the extraction of information on the spin-dependent part of the triangle-nucleon interaction. At the Indiana University Cyclotron Facility (IUCF) we studied proton-induced charge exchange reactions with results of importance to astrophysics and the nuclear few-body problem. During the first few years, the analysis of heavy-ion nucleus scattering data that had been taken prior to 1979 was completed. During the last few years we created hypernuclei by use of a kaon beam at Brookhaven National Laboratory (BNL) and an electron beam at Jefferson Laboratory (JLab). The data taken at BNL for a study of the non-mesonic weak decay of the A particle in a nucleus are still under analysis by our collaborators. The work at JLab resulted in the best resolution hypernuclear spectra measured thus far with magnetic spectrometers.

  4. Chromospheric Activity at Intermediate Ages

    NASA Astrophysics Data System (ADS)

    Giampapa, Mark; Stauffer, John; Deliyannis, Constantine; Sherry, William

    2005-08-01

    The calibration of the empirical relation between Ca II chromospheric strength and stellar age between 0.6 Gyr (Hyades) and 4.0 - 5 Gyr (M67 and the Sun) relies on the uncertain determination of ages for individual field stars in the solar neighborhood. We therefore propose to obtain WIYN/Hydra spectra of ~ 100 solar-type dwarf stars in the 1.8 Gyr old open cluster, NGC 752. This cluster contains a sample of solar-type dwarfs that is homogeneous in age and chemical composition. Furthermore, NGC 752 is the nearest-and hence brightest- cluster at an age ~ 2 Gyr. The results will yield an improved calibration of the age-activity relation at intermediate ages. In addition, we will determine if the chromospheric Ca II strengths for the solar-type stars in NGC 752 lie in the so-called "Vaughan-Preston Gap''- an apparent discontinuity in the Ca II H& K strength-(B-V) diagram found for field stars in the solar neighborhood. Our data will yield insight on the two proposed origins for the gap, namely, that it is a result of two different modes of dynamo action or that it is actually an artifact of a discontinuity in the local star formation rate. This is a resubmission of a previously approved proposal that was allocated two nights in 2004 November. The time was lost to instrument problems (Hydra gripper malfunctions) and weather. No usable data were obtained.

  5. Intermediate Filaments: Structure and Assembly.

    PubMed

    Herrmann, Harald; Aebi, Ueli

    2016-11-01

    Proteins of the intermediate filament (IF) supergene family are ubiquitous structural components that comprise, in a cell type-specific manner, the cytoskeleton proper in animal tissues. All IF proteins show a distinctly organized, extended α-helical conformation prone to form two-stranded coiled coils, which are the basic building blocks of these highly flexible, stress-resistant cytoskeletal filaments. IF proteins are highly charged, thus representing versatile polyampholytes with multiple functions. Taking vimentin, keratins, and the nuclear lamins as our prime examples, we present an overview of their molecular and structural parameters. These, in turn, document the ability of IF proteins to form distinct, highly diverse supramolecular assemblies and biomaterials found, for example, at the inner nuclear membrane, throughout the cytoplasm, and in highly complex extracellular appendages, such as hair and nails, of vertebrate organisms. Ultimately, our aim is to set the stage for a more rational understanding of the immediate effects that missense mutations in IF genes have on cellular functions and for their far-reaching impact on the development of the numerous IF diseases caused by them.

  6. Enhancement of entropic transport by intermediates.

    PubMed

    Mondal, Debasish

    2011-07-01

    Brownian particles confined in a two-dimensional enclosure that give rise to a bistable entropic potential are considered. With the introduction of an intermediate lobe, the mean first passage time from one lobe to another through the intermediate shows a turnover behavior with the variation of the stability of the entropic intermediate. The mean escape time shows a minimum for an optimal value of the barrier height of the intermediate state. A three-state model is proposed to explain the nonmonotonic behavior of the entropic transport.

  7. Intermediate filaments in nervous tissues

    PubMed Central

    Liem, RKH; Yen, S; Salomon, GD; Shelanski, ML

    1978-01-01

    Intermediate filaments have been isolated from rabbit intradural spinal nerve roots by the axonal flotation method. This method was modified to avoid exposure of axons to low ionic strength medium. The purified filaments are morphologically 75-80 percent pure. The gel electrophoretogram shows four major bands migrating at 200,000, 145,000, 68,000, and 60,000 daltons, respectively. A similar preparation from rabbit brain shows four major polypeptides with mol wt of 200,000 145,000, 68,000, and 51,000 daltons. These results indicate that the neurofilament is composed of a triplet of polypepetides with mol wt of 200,000, 145,000, and 68,000 daltons. The 51,000-dalton band that appears in brain filament preparations as the major polypeptide seems to be of glial origin. The significance of the 60,000- dalton band in the nerve root filament preparation is unclear at this time. Antibodies raised against two of the triplet proteins isolated from calf brain localize by immunofluorescence to neurons in central and peripheral nerve. On the other hand, an antibody to the 51,000-dalton polypeptide gives only glial staining in the brain, and very weak peripheral nerve staining. Prolonged exposure of axons to low ionic strength medium solubilizes almost all of the triplet polypeptides, leaving behind only the 51,000- dalton component. This would indicate that the neurofilament is soluble at low ionic strength, whereas the glial filament is not. These results indicate that neurofilaments and glial filaments are composed of different polypeptides and have different solubility characteristics. PMID:83322

  8. Nuclear structure at intermediate energies

    SciTech Connect

    Bonner, B.E.; Mutchler, G.S.

    1991-09-30

    The theme that unites the sometimes seemingly disparate experiments undertaken by the Bonner Lab Medium Energy Group is a determination to understand in detail the many facets and manifestations of the strong interaction, that which is now referred to as nonperturbative QCD. Whether we are investigating the question of just what does carry the spin of baryons, or the extent of the validity of the SU(6) wavefunctions for the excited hyperons (as will be measured in their radiative decays in our CEBAF experiment), or questions associated with the formation of a new state of matter predicted by QCD (the subject of our BNL experiments E810, E854, as well as our approved experiment at RHIC), -- all these projects share this common goal. Our other experiments represent different approaches to the same broad undertaking. LAMPF E1097 will provide definitive answers to the question of the spin dependence of the inelastic channel of pion production in the n-p interaction. FNAL E683 may well open a new field of investigation in nuclear physics: that of just how quarks and gluons interact with nuclear matter as they transverse nuclei of different sizes. In most all of the experiments mentioned above, the Bonner Lab Group is playing major leadership roles as well as doing a big fraction of the hard work that such experiments require. We use many of the facilities that are unavailable to the intermediate energy physics community and we use our expertise to design and fabricate the detectors and instrumentation that are required to perform the measurements which we decide to do.

  9. Marine Engine Mechanics. Performance Objectives. Intermediate Course.

    ERIC Educational Resources Information Center

    Jones, Marion

    Several intermediate performance objectives and corresponding criterion measures are presented for each of ten terminal objectives for a two-semester course (3 hours daily). This 540-hour intermediate course includes advanced troubleshooting techniques on outboard marine engines, inboard-outboard marine engines, inboard marine engines, boat…

  10. Some Intermediate-Level Violin Concertos.

    ERIC Educational Resources Information Center

    Abramson, Michael

    1997-01-01

    Contends that many violin students attempt difficult concertos before they are technically or musically prepared. Identifies a variety of concertos at the intermediate and advanced intermediate-level for students to study and master before attempting the advanced works by Bach and Mozart. Includes concertos by Vivaldi, Leclair, Viotti, Haydn,…

  11. Radio and Television Servicing. Intermediate Course.

    ERIC Educational Resources Information Center

    Campbell, Guy; And Others

    Several intermediate performance objectives and corresponding criterion measures are listed for each of 32 terminal objectives for an intermediate (second year) radio/TV servicing course. This 1-year course (3 hours daily) was designed to provide the student with the basic skills and knowledges necessary for entry level employment in the Radio/TV…

  12. [Intermediate phenotype studies in psychiatric disorder].

    PubMed

    Hashimoto, Ryota

    2016-02-01

    The concept of intermediate phenotype was proposed by Dr. Weinberger of the National Institute of Mental Health (NIMH). The risk genes for mental disorders define intermediate phenotypes, neurobiological characteristics observed in psychiatric disorders, and intermediate phenotypes increase the risk of mental disorders. The author worked at Dr. Weinberger's laboratory, and after returning home, introduced the concept to Japan, creating a term "Chukanhyogengata" to translate "intermediate phenotype". Intermediate phenotype has been proposed as a tool for the identification of risk genes for mental disorders, spreading the concept as a biomarker for the bridging between genes and behaviors. Intermediate phenotype studies later became one of the main pillars of psychiatric research. As a large number of data and samples are needed for intermediate phenotype research, we built a research resource database that combines the brain phenotype and bioresources. We performed genome-wide association analysis of cognitive decline in schizophrenia and identified the DEGS2 gene using this sample. This research resource database was developed for a multicenter study by COCORO (Cognitive Genetics Collaborative Research Organization). COCORO carried out genome-wide association analysis of the gray matter volume of the superior temporal gyrus and identified genome-wide significant loci. In this paper, we introduce the concept and history of intermediate phenotype study of mental illness and the latest trends. We hope to contribute to the future development of mental illness research through translational research.

  13. Some Intermediate-Level Violin Concertos.

    ERIC Educational Resources Information Center

    Abramson, Michael

    1997-01-01

    Contends that many violin students attempt difficult concertos before they are technically or musically prepared. Identifies a variety of concertos at the intermediate and advanced intermediate-level for students to study and master before attempting the advanced works by Bach and Mozart. Includes concertos by Vivaldi, Leclair, Viotti, Haydn,…

  14. Air Conditioning. Performance Objectives. Intermediate Course.

    ERIC Educational Resources Information Center

    Long, William

    Several intermediate performance objectives and corresponding criterion measures are listed for each of seven terminal objectives for an intermediate air conditioning course. The titles of the seven terminal objectives are Refrigeration Cycle, Job Requirement Skills, Air Conditioning, Trouble Shooting, Performance Test, Shop Management, and S.I.E.…

  15. Liver resection for intermediate hepatocellular carcinoma

    PubMed Central

    Yi, Peng-Sheng; Zhang, Ming; Zhao, Ji-Tong; Xu, Ming-Qing

    2016-01-01

    Hepatocellular carcinoma (HCC) is one of the most common malignant tumors in China. The Barcelona Clinic Liver Cancer (BCLC) staging system is regarded as the gold standard staging system for HCC, classifying HCC as early, intermediate, or advanced. For intermediate HCC, trans-catheter arterial chemoembolization (TACE) is recommended as the optimal strategy by the BCLC guideline. This review investigates whether liver resection is better than TACE for intermediate HCC. Based on published studies, we compare the survival benefits and complications of liver resection and TACE for intermediate HCC. We also compare the survival benefits of liver resection in early and intermediate HCC. We find that liver resection can achieve better or at least comparable survival outcomes compared with TACE for intermediate HCC; however, we do not observe a significant difference between liver resection and TACE in terms of safety and morbidity. We conclude that liver resection may improve the short- and long-term survival of carefully selected intermediate HCC patients, and the procedure may be safely performed in the management of intermediate HCC. PMID:27190577

  16. Business Machine Maintenance. Performance Objectives. Intermediate Course.

    ERIC Educational Resources Information Center

    McMinn, Robert

    Several intermediate performance objectives and corresponding criterion measures are listed for each of 28 terminal objectives presented in this guide for an intermediate business machine maintenance course at the secondary level. (For the basic course guide see CE 010 949.) Titles of the 28 terminal objective sections are Career Opportunities,…

  17. 19 CFR 122.84 - Intermediate airport.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 1 2011-04-01 2011-04-01 false Intermediate airport. 122.84 Section 122.84... Intermediate airport. (a) Application. The provisions of this section apply at any U.S. airport to which an... aircraft arrives at the next airport, the aircraft commander or agent shall make entry by filing the:...

  18. 19 CFR 122.84 - Intermediate airport.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Intermediate airport. 122.84 Section 122.84... Intermediate airport. (a) Application. The provisions of this section apply at any U.S. airport to which an... aircraft arrives at the next airport, the aircraft commander or agent shall make entry by filing the:...

  19. 19 CFR 122.84 - Intermediate airport.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 19 Customs Duties 1 2013-04-01 2013-04-01 false Intermediate airport. 122.84 Section 122.84... Intermediate airport. (a) Application. The provisions of this section apply at any U.S. airport to which an... aircraft arrives at the next airport, the aircraft commander or agent shall make entry by filing the: (1...

  20. 19 CFR 122.84 - Intermediate airport.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 19 Customs Duties 1 2014-04-01 2014-04-01 false Intermediate airport. 122.84 Section 122.84... Intermediate airport. (a) Application. The provisions of this section apply at any U.S. airport to which an... aircraft arrives at the next airport, the aircraft commander or agent shall make entry by filing the: (1...

  1. 19 CFR 122.84 - Intermediate airport.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 19 Customs Duties 1 2012-04-01 2012-04-01 false Intermediate airport. 122.84 Section 122.84... Intermediate airport. (a) Application. The provisions of this section apply at any U.S. airport to which an... aircraft arrives at the next airport, the aircraft commander or agent shall make entry by filing the: (1...

  2. Teaching Pronunciation in the Standard Intermediate Curriculum.

    ERIC Educational Resources Information Center

    Lunn, Patricia V.

    Rationales and approaches for teaching pronunciation in the intermediate foreign language classroom are discussed. Pronunciation should be taught regularly and overtly because perfecting pronunciation is an essential part of learning to communicate, and because intermediate students have enough vocabulary to generalize pronunciation rules to new…

  3. Automotive Body Repair. Performance Objectives. Intermediate Course.

    ERIC Educational Resources Information Center

    Lang, Thomas

    Several intermediate performance objectives and corresponding criterion measures are listed for each of 10 terminal objectives for an intermediate automotive body repair and refinishing course. The materials were developed for a two-semester (3 hours daily) course for specialized classrooms, shop, and practical experiences designed to enable the…

  4. Automotive Body Repair. Performance Objectives. Intermediate Course.

    ERIC Educational Resources Information Center

    Lang, Thomas

    Several intermediate performance objectives and corresponding criterion measures are listed for each of 10 terminal objectives for an intermediate automotive body repair and refinishing course. The materials were developed for a two-semester (3 hours daily) course for specialized classrooms, shop, and practical experiences designed to enable the…

  5. Air Conditioning. Performance Objectives. Intermediate Course.

    ERIC Educational Resources Information Center

    Long, William

    Several intermediate performance objectives and corresponding criterion measures are listed for each of seven terminal objectives for an intermediate air conditioning course. The titles of the seven terminal objectives are Refrigeration Cycle, Job Requirement Skills, Air Conditioning, Trouble Shooting, Performance Test, Shop Management, and S.I.E.…

  6. Gasoline Engine Mechanics. Performance Objectives. Intermediate Course.

    ERIC Educational Resources Information Center

    Jones, Marion

    Several intermediate performance objectives and corresponding criterion measures are listed for each of six terminal objectives presented in this curriculum guide for an intermediate gasoline engine mechanics course at the secondary level. (For the beginning course guide see CE 010 947.) The materials were developed for a two-semester (2 hour…

  7. Appliance Services. Intermediate Course. Career Education.

    ERIC Educational Resources Information Center

    Killough, Joseph

    Several intermediate performance objectives and corresponding criterion measures are listed for each of 16 terminal objectives for an intermediate appliance repair course. The materials were developed for a 36-week course (3 hours daily) covering the areas of refrigeration, maintenance, repair, and troubleshooting of refrigerators and air…

  8. Epithelial Intermediate Filaments: Guardians against Microbial Infection?

    PubMed Central

    Geisler, Florian; Leube, Rudolf E.

    2016-01-01

    Intermediate filaments are abundant cytoskeletal components of epithelial tissues. They have been implicated in overall stress protection. A hitherto poorly investigated area of research is the function of intermediate filaments as a barrier to microbial infection. This review summarizes the accumulating knowledge about this interaction. It first emphasizes the unique spatial organization of the keratin intermediate filament cytoskeleton in different epithelial tissues to protect the organism against microbial insults. We then present examples of direct interaction between viral, bacterial, and parasitic proteins and the intermediate filament system and describe how this affects the microbe-host interaction by modulating the epithelial cytoskeleton, the progression of infection, and host response. These observations not only provide novel insights into the dynamics and function of intermediate filaments but also indicate future avenues to combat microbial infection. PMID:27355965

  9. Effect of Intermediate Hosts on Emerging Zoonoses.

    PubMed

    Cui, Jing-An; Chen, Fangyuan; Fan, Shengjie

    2017-08-01

    Most emerging zoonotic pathogens originate from animals. They can directly infect humans through natural reservoirs or indirectly through intermediate hosts. As a bridge, an intermediate host plays different roles in the transmission of zoonotic pathogens. In this study, we present three types of pathogen transmission to evaluate the effect of intermediate hosts on emerging zoonotic diseases in human epidemics. These types are identified as follows: TYPE 1, pathogen transmission without an intermediate host for comparison; TYPE 2, pathogen transmission with an intermediate host as an amplifier; and TYPE 3, pathogen transmission with an intermediate host as a vessel for genetic variation. In addition, we established three mathematical models to elucidate the mechanisms underlying zoonotic disease transmission according to these three types. Stability analysis indicated that the existence of intermediate hosts increased the difficulty of controlling zoonotic diseases because of more difficult conditions to satisfy for the disease to die out. The human epidemic would die out under the following conditions: TYPE 1: [Formula: see text] and [Formula: see text]; TYPE 2: [Formula: see text], [Formula: see text], and [Formula: see text]; and TYPE 3: [Formula: see text], [Formula: see text], [Formula: see text], and [Formula: see text] Simulation with similar parameters demonstrated that intermediate hosts could change the peak time and number of infected humans during a human epidemic; intermediate hosts also exerted different effects on controlling the prevalence of a human epidemic with natural reservoirs in different periods, which is important in addressing problems in public health. Monitoring and controlling the number of natural reservoirs and intermediate hosts at the right time would successfully manage and prevent the prevalence of emerging zoonoses in humans.

  10. Electricity Electronics for Intermediate and Junior High Schools.

    ERIC Educational Resources Information Center

    New York City Board of Education, Brooklyn, NY. Bureau of Curriculum Development.

    This manual has been developed to aid the industrial arts teacher of electricity or electronics in implementing his course. It has been designed for beginning teachers and experienced instructors as a source for planning the term's work. Although programmed at the seventh or eighth grade level, course work is brought out in detail and could serve…

  11. SCIENCE FOR GEORGIA SCHOOLS, VOLUME II, INTERMEDIATE MANUAL.

    ERIC Educational Resources Information Center

    NIX, JACK P.

    SUGGESTIONS FOR THE TEACHING OF SCIENCE IN GRADES 4-6 ARE INCLUDED IN THIS GUIDE FOR ELEMENTARY TEACHERS. INTRODUCTORY SECTIONS ARE DEVOTED TO (1) BASIC CONCEPTS AND UNDERSTANDINGS, (2) AN EXPLANATION OF THE STEPS INVOLVED IN PROBLEM-SOLVING, (3) A FORMAT FOR THE DEVELOPMENT OF TEACHING UNITS, (4) THE APPLICATION OF PROBLEM-SOLVING TECHNIQUES TO…

  12. Number Frequency in L1 Differentially Affects Immediate Serial Recall of Numbers in L2 between Beginning and Intermediate Learners

    ERIC Educational Resources Information Center

    Sumioka, Norihiko; Williams, Atsuko; Yamada, Jun

    2016-01-01

    A list number recall test in English (L2) was administered to both Japanese (L1) students with beginning-level English proficiency who attended evening high school and Japanese college students with intermediate-level English proficiency. The major findings were that, only for the high school group, the small numbers 1 and 2 in middle positions of…

  13. Number Frequency in L1 Differentially Affects Immediate Serial Recall of Numbers in L2 between Beginning and Intermediate Learners

    ERIC Educational Resources Information Center

    Sumioka, Norihiko; Williams, Atsuko; Yamada, Jun

    2016-01-01

    A list number recall test in English (L2) was administered to both Japanese (L1) students with beginning-level English proficiency who attended evening high school and Japanese college students with intermediate-level English proficiency. The major findings were that, only for the high school group, the small numbers 1 and 2 in middle positions of…

  14. Science and Practice of Coaching a Strength Training Program for Novice and Intermediate-Level Athletes.

    ERIC Educational Resources Information Center

    Baker, Daniel

    2001-01-01

    Addresses various aspects of the athletic coaching process in strength training, including: teaching and coaching exercises to novice and intermediate level athletes (typical high school and younger college aged athletes); technical analysis and modification of student technique; student motivation; goal setting; reinforcement; and the overall…

  15. Red House 1969-1972: The Case for "Intermediate" Educational Institutions

    ERIC Educational Resources Information Center

    Williams, Keith

    2012-01-01

    In October 2010 the government confirmed it would introduce a "pupil premium" payable to schools with disadvantaged pupils. This shift towards resourcing by group rather than area may mark the closing of another chapter in efforts to produce a more meritocratic education system utilising what might be termed "intermediate"…

  16. Writing Process Products in Intermediate-Grade Children with and without Language-Based Learning Disabilities

    ERIC Educational Resources Information Center

    Koutsoftas, Anthony D.

    2016-01-01

    Purpose: Difficulties with written expression are an important consideration in the assessment and treatment of school-age children. This study evaluated how intermediate-grade children with and without written language difficulties fared on a writing task housed within the Hayes and Berninger (2014) writing process framework. Method: Sixty-four…

  17. Red House 1969-1972: The Case for "Intermediate" Educational Institutions

    ERIC Educational Resources Information Center

    Williams, Keith

    2012-01-01

    In October 2010 the government confirmed it would introduce a "pupil premium" payable to schools with disadvantaged pupils. This shift towards resourcing by group rather than area may mark the closing of another chapter in efforts to produce a more meritocratic education system utilising what might be termed "intermediate"…

  18. Intermediate Mathematics, Student's Text, Part II, Unit No. 18. Revised Edition.

    ERIC Educational Resources Information Center

    Allen, Frank B.; And Others

    This is part two of a two-part SMSG intermediate mathematics text for high school students. The aim of the text is to focus attention on mathematical ideas which are appropriate for study by college-capable students in the eleventh grade. Chapter topics include number systems, an introduction to coordinate geometry in the plane, the function…

  19. Industrial Arts--Metals Technology: A Curriculum Guide for Intermediate and Secondary Level Programs.

    ERIC Educational Resources Information Center

    Missouri Council for Industrial Arts Education.

    The curriculum outline is designed to aid the instructor in developing a more complete course of study, for intermediate and secondary school students, to give the student an understanding of some of the tools, materials, processes, products, occupational opportunities, requirements, and working conditions associated with the metal and metal…

  20. Ecologia: Spanish Ecology Packet Resource Units and Materials for Intermediate and Advanced Spanish Classes.

    ERIC Educational Resources Information Center

    Bell, Mozelle Sawyer; Arribas, E. Jaime

    This Spanish ecology packet contains resource units and materials for intermediate and advanced Spanish classes. It is designed to be used for individual and small-group instruction in the senior high school to supplement the Spanish language curriculum. Included are articles, pictures, and cartoons from Spanish-language newspapers and magazines…

  1. An Interdisciplinary Program Incorporating Population Studies for Intermediate Grades. Sedro-Woolley Project Report No. 13.

    ERIC Educational Resources Information Center

    Jungblom, Edwin N.

    The publication contains exercises on population education which can be used in social studies and science classes in grades 4-7. Although the language of the material is geared to the intermediate grades, the exercises can easily be adapted for primary, high school, and adult education. The publication's major objective is to change the lifestyle…

  2. Missouri Assessment Program (MAP), Spring 2000: Intermediate Communication Arts, Released Items, Grade 7.

    ERIC Educational Resources Information Center

    Missouri State Dept. of Elementary and Secondary Education, Jefferson City.

    This document deals with testing in intermediate communication arts for seventh graders in Missouri public schools. The document contains the following items from the Session 1 Test Booklet: "Swimming in Snow" (Diana C. Conway) (Items 1, 2, and 5); "Discovery" (Marion Dane Bauer) (Item 13); writing prompt; and a writer's…

  3. Linking Laptops to Learning: Analysis of a 1:1 Environment with Intermediate Learners

    ERIC Educational Resources Information Center

    Cottone, Mark Anthony

    2013-01-01

    The purpose of this study is to examine how the 1:1 laptop initiative impacted student achievement for the students at a single intermediate school (grades 4-6) in Mooresville, North Carolina. Researchers Dunleavy, Dexter, & Heinecke, 2007; Mouza, 2008; O'Dwyer, Russell, Bebell & Tucker-Seeley, 2005 have called for additional research…

  4. Stimulating Creative Writing Through Literature: A Guide for Teachers of the Intermediate Grades.

    ERIC Educational Resources Information Center

    Pilon, Alice Barbara Cummings

    A structured writing program for the intermediate grades was designed, utilizing such children's literature as poems, legends, fairy tales, tall tales, and books to stimulate elementary school children to write creatively. Chapters in the teacher's guide for the program present many specific suggestions and activities to help children (1) use…

  5. Science and Practice of Coaching a Strength Training Program for Novice and Intermediate-Level Athletes.

    ERIC Educational Resources Information Center

    Baker, Daniel

    2001-01-01

    Addresses various aspects of the athletic coaching process in strength training, including: teaching and coaching exercises to novice and intermediate level athletes (typical high school and younger college aged athletes); technical analysis and modification of student technique; student motivation; goal setting; reinforcement; and the overall…

  6. Missouri Assessment Program (MAP), Spring 1999: Intermediate Communication Arts, Released Items, Grade 7.

    ERIC Educational Resources Information Center

    Missouri State Dept. of Elementary and Secondary Education, Jefferson City.

    This document deals with testing in intermediate communication arts for seventh graders in Missouri public schools. The document contains the following items from the Test Booklet: "Under the Rice Moon" (Rhiannon Puck); "Dogspirit" (Gary Paulsen) (Session 1, Items 4, 5, 6, and 8); a writing prompt; and a writer's checklist. It…

  7. Industrial Arts--Woods and Wood Technology: A Curriculum Guide for Intermediate and Secondary Level Programs.

    ERIC Educational Resources Information Center

    Missouri Council for Industrial Arts Education.

    The curriculum outline is designed to aid the instructor in developing a more complete course of study in woods and wood technology for intermediate and secondary school students. The guide is introduced by a discussion of objectives fundamental to a sound program of industrial arts education, followed by an outline and objectives for the content…

  8. Linking Laptops to Learning: Analysis of a 1:1 Environment with Intermediate Learners

    ERIC Educational Resources Information Center

    Cottone, Mark Anthony

    2013-01-01

    The purpose of this study is to examine how the 1:1 laptop initiative impacted student achievement for the students at a single intermediate school (grades 4-6) in Mooresville, North Carolina. Researchers Dunleavy, Dexter, & Heinecke, 2007; Mouza, 2008; O'Dwyer, Russell, Bebell & Tucker-Seeley, 2005 have called for additional research…

  9. Writing Process Products in Intermediate-Grade Children with and without Language-Based Learning Disabilities

    ERIC Educational Resources Information Center

    Koutsoftas, Anthony D.

    2016-01-01

    Purpose: Difficulties with written expression are an important consideration in the assessment and treatment of school-age children. This study evaluated how intermediate-grade children with and without written language difficulties fared on a writing task housed within the Hayes and Berninger (2014) writing process framework. Method: Sixty-four…

  10. Biocatalysis: synthesis of chiral intermediates for drugs.

    PubMed

    Patel, Ramesh N

    2006-11-01

    Chirality is a key factor in the safety and efficacy of many drug products and thus the production of single enantiomers of drug intermediates has become increasingly important in the pharmaceutical industry. Chiral intermediates and fine chemicals are in high demand for the bulk preparation of drug substances and agricultural products. There has been an increasing awareness of the enormous potential of the use of microorganisms and microorganism-derived enzymes for the transformation of synthetic chemicals with high chemo-, regio- and enantioselectivities. In this article, biocatalytic processes are described for the synthesis of chiral intermediates for drugs.

  11. Ethnic Studies: Elective Resource Bulletin. Junior High School, Intermediate School, High School.

    ERIC Educational Resources Information Center

    Fisher, Norman; Kobliner, Richard

    The five month course of study for grades 9 through 12 offers activity guidelines and a variety of resource materials on American ethnic groups of Chinese, Irish, Italian, and Jewish persons. Focus is upon the cultural diversity of the American people, and the adjustments and contributions of the ethnic groups. The aim of the course is for…

  12. The deterioration of intermediate moisture foods

    NASA Technical Reports Server (NTRS)

    Labruza, T. P.

    1971-01-01

    Deteriorative reactions are low and food quality high if intermediate moisture content of a food is held at a water activity of 0.6 to 0.75. Information is of interest to food processing and packaging industry.

  13. Intermediate/Advanced Research Design and Statistics

    NASA Technical Reports Server (NTRS)

    Ploutz-Snyder, Robert

    2009-01-01

    The purpose of this module is To provide Institutional Researchers (IRs) with an understanding of the principles of advanced research design and the intermediate/advanced statistical procedures consistent with such designs

  14. Data requirements for intermediate energy nuclear applications

    SciTech Connect

    Pearlstein, S.

    1990-01-01

    Several applications that include spallation neutron sources, space radiation effects, biomedical isotope production, accelerator shielding and radiation therapy make use of intermediate energy nuclear data extending to several GeV. The overlapping data needs of these applications are discussed in terms of what projectiles, targets and reactions are of interest. Included is a discussion of what is generally known about these data and what is needed to facilitate their use in intermediate energy applications. 40 refs., 2 figs., 2 tabs.

  15. Intermediate Temperature Brittleness in Metallic Glasses.

    PubMed

    Wang, Chao; Cao, Qing Ping; Wang, Xiao Dong; Zhang, Dong Xian; Ramamurty, Upadrasta; Narayan, Ramasubramanian Lakshmi; Jiang, Jian-Zhong

    2017-04-01

    All metallic glasses (MGs), irrespective of their compositions, become brittle in the intermediate temperature range of 0.6-0.7 Tg However, most materials are expected to carry higher strains during deformation with increasing temperature. This behavior of MGs is explained by describing the competition between shear banding and diffusive relaxation processes, and is reminiscent of the "intermediate temperature ductility minimum" observed in polycrystalline metals. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  16. 29 CFR 452.123 - Elections of intermediate body officers.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 2 2011-07-01 2011-07-01 false Elections of intermediate body officers. 452.123 Section... intermediate body officers. Section 401(d) states that officers of intermediate bodies shall be elected either... intermediate bodies. Such delegates may therefore participate in the election of officers of intermediate...

  17. 29 CFR 452.123 - Elections of intermediate body officers.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 2 2012-07-01 2012-07-01 false Elections of intermediate body officers. 452.123 Section... intermediate body officers. Section 401(d) states that officers of intermediate bodies shall be elected either... intermediate bodies. Such delegates may therefore participate in the election of officers of intermediate...

  18. 29 CFR 452.123 - Elections of intermediate body officers.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 2 2010-07-01 2010-07-01 false Elections of intermediate body officers. 452.123 Section... intermediate body officers. Section 401(d) states that officers of intermediate bodies shall be elected either... intermediate bodies. Such delegates may therefore participate in the election of officers of intermediate...

  19. 29 CFR 452.123 - Elections of intermediate body officers.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 2 2013-07-01 2013-07-01 false Elections of intermediate body officers. 452.123 Section... intermediate body officers. Section 401(d) states that officers of intermediate bodies shall be elected either... intermediate bodies. Such delegates may therefore participate in the election of officers of intermediate...

  20. 29 CFR 452.123 - Elections of intermediate body officers.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 2 2014-07-01 2014-07-01 false Elections of intermediate body officers. 452.123 Section... intermediate body officers. Section 401(d) states that officers of intermediate bodies shall be elected either... intermediate bodies. Such delegates may therefore participate in the election of officers of intermediate...

  1. Cytoplasmic peptidoglycan intermediate levels in Staphylococcus aureus.

    PubMed

    Vemula, Harika; Ayon, Navid J; Gutheil, William G

    2016-02-01

    Intracellular cytoplasmic peptidoglycan (PG) intermediate levels were determined in Staphylococcus aureus during log-phase growth in enriched media. Levels of UDP-linked intermediates were quantitatively determined using ion pairing LC-MS/MS in negative mode, and amine intermediates were quantitatively determined stereospecifically as their Marfey's reagent derivatives in positive mode. Levels of UDP-linked intermediates in S. aureus varied from 1.4 μM for UDP-GlcNAc-Enolpyruvyate to 1200 μM for UDP-MurNAc. Levels of amine intermediates (L-Ala, D-Ala, D-Ala-D-Ala, L-Glu, D-Glu, and L-Lys) varied over a range of from 860 μM for D-Ala-D-Ala to 30-260 mM for the others. Total PG was determined from the D-Glu content of isolated PG, and used to estimate the rate of PG synthesis (in terms of cytoplasmic metabolite flux) as 690 μM/min. The total UDP-linked intermediates pool (2490 μM) is therefore sufficient to sustain growth for 3.6 min. Comparison of UDP-linked metabolite levels with published pathway enzyme characteristics demonstrates that enzymes on the UDP-branch range from >80% saturation for MurA, Z, and C, to <5% saturation for MurB. Metabolite levels were compared with literature values for Escherichia coli, with the major difference in UDP-intermediates being the level of UDP-MurNAc, which was high in S. aureus (1200 μM) and low in E. coli (45 μM).

  2. School Social Capital and Secondary Education Plans

    ERIC Educational Resources Information Center

    Schuchart, Claudia

    2013-01-01

    This article intends to identify the effects of school social capital on the educational plans of students, particularly those staying in school and obtaining an intermediate certificate. It is hypothesised that social capital helps to explain individual educational plans and differences between schools regarding the amount of students with…

  3. School Social Capital and Secondary Education Plans

    ERIC Educational Resources Information Center

    Schuchart, Claudia

    2013-01-01

    This article intends to identify the effects of school social capital on the educational plans of students, particularly those staying in school and obtaining an intermediate certificate. It is hypothesised that social capital helps to explain individual educational plans and differences between schools regarding the amount of students with…

  4. Hydroxyacetone production from C3 Criegee intermediates

    DOE PAGES

    Taatjes, Craig A.; Liu, Fang; Rotavera, Brandon; ...

    2016-12-21

    Hydroxyacetone (CH3C(O)CH2OH) is observed as a stable end product from reactions of the (CH3)2COO Criegee intermediate, acetone oxide, in a flow tube coupled with multiplexed photoionization mass spectrometer detection. In the experiment, the isomers at m/z = 74 are distinguished by their different photoionization spectra and reaction times. Hydroxyacetone is observed as a persistent signal at longer reaction times at a higher photoionization threshold of ca. 9.7 eV than Criegee intermediate and definitively identified by comparison with the known photoionization spectrum. Complementary electronic structure calculations reveal multiple possible reaction pathways for hydroxyacetone formation, including unimolecular isomerization via hydrogen atom transfermore » and –OH group migration as well as self-reaction of Criegee intermediates. Varying the concentration of Criegee intermediates suggests contributions from both unimolecular and self-reaction pathways to hydroxyacetone. As a result, the hydroxyacetone end product can provide an effective, stable marker for the production of transient Criegee intermediates in future studies of alkene ozonolysis.« less

  5. Hydroxyacetone Production From C3 Criegee Intermediates.

    PubMed

    Taatjes, Craig A; Liu, Fang; Rotavera, Brandon; Kumar, Manoj; Caravan, Rebecca; Osborn, David L; Thompson, Ward H; Lester, Marsha I

    2017-01-12

    Hydroxyacetone (CH3C(O)CH2OH) is observed as a stable end product from reactions of the (CH3)2COO Criegee intermediate, acetone oxide, in a flow tube coupled with multiplexed photoionization mass spectrometer detection. In the experiment, the isomers at m/z = 74 are distinguished by their different photoionization spectra and reaction times. Hydroxyacetone is observed as a persistent signal at longer reaction times at a higher photoionization threshold of ca. 9.7 eV than Criegee intermediate and definitively identified by comparison with the known photoionization spectrum. Complementary electronic structure calculations reveal multiple possible reaction pathways for hydroxyacetone formation, including unimolecular isomerization via hydrogen atom transfer and -OH group migration as well as self-reaction of Criegee intermediates. Varying the concentration of Criegee intermediates suggests contributions from both unimolecular and self-reaction pathways to hydroxyacetone. The hydroxyacetone end product can provide an effective, stable marker for the production of transient Criegee intermediates in future studies of alkene ozonolysis.

  6. Photon ratchet intermediate band solar cells

    NASA Astrophysics Data System (ADS)

    Yoshida, M.; Ekins-Daukes, N. J.; Farrell, D. J.; Phillips, C. C.

    2012-06-01

    In this paper, we propose an innovative concept for solar power conversion—the "photon ratchet" intermediate band solar cell (IBSC)—which may increase the photovoltaic energy conversion efficiency of IBSCs by increasing the lifetime of charge carriers in the intermediate state. The limiting efficiency calculation for this concept shows that the efficiency can be increased by introducing a fast thermal transition of carriers into a non-emissive state. At 1 sun, the introduction of a "ratchet band" results in an increase of efficiency from 46.8% to 48.5%, due to suppression of entropy generation.

  7. Intermediate load-center photovoltaic application experiments

    SciTech Connect

    Burgess, E. L.

    1980-01-01

    A total of nine intermediate load-center photovoltaic systems were carried into the construction phase this year. These nine systems range in size from 20 to 225 kW/sub p/ electrical output and total almost 1 MW/sub p/. They are being installed in a diverse set of applications and locations and represent the bulk of the photovoltaic initial system evaluation experiments (ISEE) for the intermediate load-center sector. Each of these experiments are briefly described and the status of the construction phase is given for each project.

  8. Intermediate-energy nuclear chemistry workshop

    SciTech Connect

    Butler, G.W.; Giesler, G.C.; Liu, L.C.; Dropesky, B.J.; Knight, J.D.; Lucero, F.; Orth, C.J.

    1981-05-01

    This report contains the proceedings of the LAMPF Intermediate-Energy Nuclear Chemistry Workshop held in Los Alamos, New Mexico, June 23-27, 1980. The first two days of the Workshop were devoted to invited review talks highlighting current experimental and theoretical research activities in intermediate-energy nuclear chemistry and physics. Working panels representing major topic areas carried out indepth appraisals of present research and formulated recommendations for future research directions. The major topic areas were Pion-Nucleus Reactions, Nucleon-Nucleus Reactions and Nuclei Far from Stability, Mesonic Atoms, Exotic Interactions, New Theoretical Approaches, and New Experimental Techniques and New Nuclear Chemistry Facilities.

  9. Genetics of alcoholism using intermediate phenotypes.

    PubMed

    Enoch, Mary-Anne; Schuckit, Marc A; Johnson, Bankole A; Goldman, David

    2003-02-01

    This article represents the proceedings of a symposium at the 2002 meeting of the Research Society on Alcoholism in San Francisco, CA. It was organized by Mary-Anne Enoch and David Goldman and chaired by David Goldman. The presentations were (1) Two functional polymorphisms and their intermediate phenotypes in complex behaviors: COMT/executive cognition and anxiety and HTT/anxiety, by David Goldman; (2) Role of the EEG in determining genetic risk for alcoholism and anxiety disorders, by Mary-Anne Enoch; (3) The response to alcohol as an intermediate phenotype for alcoholism, by Marc A. Schuckit; and (4) Pharmacogenomic approaches to alcoholism treatment: toward a hypothesis, by Bankole A. Johnson.

  10. Nucleation via an unstable intermediate phase.

    PubMed

    Sear, Richard P

    2009-08-21

    The pathway for crystallization from dilute vapors and solutions is often observed to take a detour via a liquid or concentrated-solution phase. For example, in moist subzero air, droplets of liquid water form, which then freeze. In this example and in many others, an intermediate phase (here liquid water) is dramatically accelerating the kinetics of a phase transition between two other phases (water vapor and ice). Here we study this phenomenon via exact computer simulations of a simple lattice model. Surprisingly, we find that the rate of nucleation of the new equilibrium phase is actually fastest when the intermediate phase is slightly unstable in the bulk, i.e., has a slightly higher free energy than the phase we start in. Nucleation occurs at a concave part of the surface and microscopic amounts of the intermediate phase can form there even before the phase is stable in the bulk. As the nucleus of the equilibrium phase is microscopic, this allows nucleation to occur effectively in the intermediate phase before it is stable in the bulk.

  11. NTTC Course 215: Intermediate Water Examination.

    ERIC Educational Resources Information Center

    Department of the Navy, Washington, DC.

    This publication is the examination booklet used for a home study course in water treatment. This course is the intermediate part of a series produced by the Department of the Navy. This publication is designed to be used in conjunction with a textbook. Each of the two examinations contained in this document are referenced to a section of the…

  12. What Should be Taught in Intermediate Macroeconomics?

    ERIC Educational Resources Information Center

    de Araujo, Pedro; O'Sullivan, Roisin; Simpson, Nicole B.

    2013-01-01

    A lack of consensus remains on what should form the theoretical core of the undergraduate intermediate macroeconomic course. In determining how to deal with the Keynesian/classical divide, instructors must decide whether to follow the modern approach of building macroeconomic relationships from micro foundations, or to use the traditional approach…

  13. Teaching Vocabulary and Morphology in Intermediate Grades

    ERIC Educational Resources Information Center

    Palumbo, Anthony; Kramer-Vida, Louisa; Hunt, Carolyn V.

    2015-01-01

    Direct vocabulary instruction of Tier 2 and Tier 3 words in intermediate-grade curricula is an important tool of literacy instruction because English is a language grafted from many roots and has not developed a one-to-one phoneme-grapheme correspondence. In addition to knowing graphemes and phonemes, students must formally learn words that cross…

  14. Bridge: Intelligent Tutoring with Intermediate Representations

    DTIC Science & Technology

    1988-05-01

    Research and Development Center and Psychology Department University of Pittsburgh Pittsburgh, PA. 15260 The Artificial Intelligence and Psychology...problem never introduces more than one unfamiliar plan. Inteligent Tutoring With Intermediate Representations - Bonar and Cunniigbam 4 You must have a... Inteligent Tutoring With ntermediate Representations - Bonar and Cunningham 7 The requirements are specified at four differcnt levels, corresponding to

  15. Fostering teamwork in an intermediate care unit.

    PubMed

    Spence, Heather; Cappleman, Julia

    2011-06-01

    The government has emphasised that, to deliver high quality, integrated care, staff must work across organisational boundaries using a team approach so that everyone works towards the same goals. This article describes how one NHS-managed intermediate care unit has integrated care staff employed by the independent sector.

  16. NTTC Course 215: Intermediate Water Examination.

    ERIC Educational Resources Information Center

    Department of the Navy, Washington, DC.

    This publication is the examination booklet used for a home study course in water treatment. This course is the intermediate part of a series produced by the Department of the Navy. This publication is designed to be used in conjunction with a textbook. Each of the two examinations contained in this document are referenced to a section of the…

  17. Intermediate Amharic Cultural Reader. Final Report.

    ERIC Educational Resources Information Center

    Leslau, Wolf

    This reader is intended to provide material for the intermediate-level student of Amharic, as well as to introduce the student to the cultural and social life of Ethiopia. The 39 texts were each prepared by a different student at Haile Selassie I University, thus providing the reader with a variety of language styles. The Amharic texts are…

  18. What Should be Taught in Intermediate Macroeconomics?

    ERIC Educational Resources Information Center

    de Araujo, Pedro; O'Sullivan, Roisin; Simpson, Nicole B.

    2013-01-01

    A lack of consensus remains on what should form the theoretical core of the undergraduate intermediate macroeconomic course. In determining how to deal with the Keynesian/classical divide, instructors must decide whether to follow the modern approach of building macroeconomic relationships from micro foundations, or to use the traditional approach…

  19. Using Drosophila for Studies of Intermediate Filaments.

    PubMed

    Bohnekamp, Jens; Cryderman, Diane E; Thiemann, Dylan A; Magin, Thomas M; Wallrath, Lori L

    2016-01-01

    Drosophila melanogaster is a useful organism for determining protein function and modeling human disease. Drosophila offers a rapid generation time and an abundance of genomic resources and genetic tools. Conservation in protein structure, signaling pathways, and developmental processes make studies performed in Drosophila relevant to other species, including humans. Drosophila models have been generated for neurodegenerative diseases, muscular dystrophy, cancer, and many other disorders. Recently, intermediate filament protein diseases have been modeled in Drosophila. These models have revealed novel mechanisms of pathology, illuminated potential new routes of therapy, and make whole organism compound screens feasible. The goal of this chapter is to outline steps to study intermediate filament function and model intermediate filament-associated diseases in Drosophila. The steps are general and can be applied to study the function of almost any protein. The protocols outlined here are for both the novice and experienced Drosophila researcher, allowing the rich developmental and cell biology that Drosophila offers to be applied to studies of intermediate filaments. Copyright © 2016 Elsevier Inc. All rights reserved.

  20. Membrane Fission: Model for Intermediate Structures

    PubMed Central

    Kozlovsky, Yonathan; Kozlov, Michael M.

    2003-01-01

    Membrane budding-fission is a fundamental process generating intracellular carriers of proteins. Earlier works were focused only on formation of coated buds connected to the initial membrane by narrow membrane necks. We present the theoretical analysis of the whole pathway of budding-fission, including the crucial stage where the membrane neck undergoes fission and the carrier separates from the donor membrane. We consider two successive intermediates of the reaction: 1), a constricted membrane neck coming out of aperture of the assembling protein coat, and 2), hemifission intermediate resulting from self-fusion of the inner monolayer of the neck, while its outer monolayer remains continuous. Transformation of the constricted neck into the hemifission intermediate is driven by the membrane stress produced in the neck by the protein coat. Although apparently similar to hemifusion, the fission is predicted to have an opposite dependence on the monolayer spontaneous curvature. Analysis of the further stages of the process demonstrates that in all practically important cases the hemifission intermediate decays spontaneously into two separate membranes, thereby completing the fission process. We formulate the “job description” for fission proteins by calculating the energy they have to deliver and the radii of the protein coat aperture which have to be reached to drive the fission process. PMID:12829467

  1. A Concurrent Support Course for Intermediate Algebra

    ERIC Educational Resources Information Center

    Cooper, Cameron I.

    2011-01-01

    This article summarizes the creation and implementation of a concurrent support class for TRS 92--Intermediate Algebra, a developmental mathematics course at Fort Lewis College in Durango, Colorado. The concurrent course outlined in this article demonstrates a statistically significant increase in student success rates since its inception.…

  2. Capabilities of proprietary intermediate telehealth devices.

    PubMed

    Adeogun, Oluseun; Tiwari, Ashutosh; Alcock, Jeffrey R

    2011-11-01

    Proprietary intermediate telehealth devices are those which are specifically designed as connectors between the entities of telehealth systems. This article seeks to understand what are the capabilities of such devices and then to investigate how these are clustered on the current generation of devices. Fourteen current-generation devices available from 12 device providers were selected and analyzed. Four categories of questions were composed to evaluate the devices: setup/configuration, available features, inputs, and outputs. Data were collected and synthesized on the following capabilities: availability from suppliers, setup, environments of use, multiple-condition monitoring, multiuser capabilities, prompts, reminders and alerts, interaction with the health professional, access to historical data, device inputs, and their transfer technology. There are three main roles for proprietary intermediate devices in telehealth systems: displaying information to the patient; receiving data manually/automatically; forwarding results and questionnaire responses to another entity. Provider Perspective: Intermediate devices are usually part of closed proprietary systems. Providers produce disease-customisable devices. Connectivity is considerably ahead of the current generation of point-of-care devices. However, little data are available on connection to rest of the proprietary system. Patient Perspective: It shows clear benefit that one intermediate device can be potentially used with several chronic conditions. Simple setup, authentication procedures, and automatic data transfer are key design aspects. Health Professional Perspective: Little direct interaction with the health professional was observed. Payer Perspective: Details of costs of devices are generally unavailable; system providers indicate that cost variability is based on "user requirements."

  3. Teaching Vocabulary and Morphology in Intermediate Grades

    ERIC Educational Resources Information Center

    Palumbo, Anthony; Kramer-Vida, Louisa; Hunt, Carolyn V.

    2015-01-01

    Direct vocabulary instruction of Tier 2 and Tier 3 words in intermediate-grade curricula is an important tool of literacy instruction because English is a language grafted from many roots and has not developed a one-to-one phoneme-grapheme correspondence. In addition to knowing graphemes and phonemes, students must formally learn words that cross…

  4. The intermediate anomaly. [satellite orbit integration

    NASA Technical Reports Server (NTRS)

    Nacozy, P.

    1977-01-01

    Time transformations of the equation dt = cr to the n ds, where s is a variable called the intermediate anomaly, are known to reduce global error in the solution of gravitational systems obtained by numerical integration. Attention is given to the Sundman time transformation, and its relation to equations of Keplerian elliptical motion.

  5. Intermediate Tamil: A Self-Instructional Method.

    ERIC Educational Resources Information Center

    Schiffman, Harold

    This self-instructional method for learning an intermediate level of Tamil is designed to follow an elementary level such as "Conversational Tamil." The material in this text concentrates on grammatical constructions not covered in that elementary text, particularly negatives of all kinds; in addition, this text uses the same transcription and the…

  6. Predicting Student Success in Intermediate Accounting I.

    ERIC Educational Resources Information Center

    Morgan, Robert G.; And Others

    1985-01-01

    A study was conducted to find some quantitative predictors of student success in Intermediate Accounting I that an advisor can use as an aid in student counseling. The AICPA Level I Form C test and the average grade in principles courses proved to be reasonable predictors of success. (CT)

  7. Intermediate filaments: a role in epithelial polarity

    PubMed Central

    Oriolo, Andrea S.; Wald, Flavia A.; Ramsauer, Victoria P.; Salas, Pedro J.I.

    2007-01-01

    Intermediate filaments have long been considered mechanical components of the cell that provide resistance to deformation stress. Practical experimental problems, including insolubility, lack of good pharmacological antagonists, and the paucity of powerful genetic models, have handicapped the research of other functions. In single-layered epithelial cells, keratin intermediate filaments are cortical, either apically polarized or apico-lateral. This review analyzes phenotypes of genetic manipulations of simple epithelial cell keratins in mice and C. elegans that strongly suggest a role of keratins in apico-basal polarization and membrane traffic. Published evidence that intermediate filaments can act as scaffolds for proteins involved in membrane traffic and signaling is also discussed. Such a scaffolding function would generate a highly polarized compartment within the cytoplasm of simple epithelial cells. While in most cases mechanistic explanations for the keratin-null or overexpression phenotypes are still missing, it is hoped investigators will be encouraged to study these as yet poorly understood functions of intermediate filaments. PMID:17425955

  8. A Concurrent Support Course for Intermediate Algebra

    ERIC Educational Resources Information Center

    Cooper, Cameron I.

    2011-01-01

    This article summarizes the creation and implementation of a concurrent support class for TRS 92--Intermediate Algebra, a developmental mathematics course at Fort Lewis College in Durango, Colorado. The concurrent course outlined in this article demonstrates a statistically significant increase in student success rates since its inception.…

  9. Health Education for Special Children: Intermediate EMR.

    ERIC Educational Resources Information Center

    Brodie, Patrick; And Others

    Intended for teachers and administrators in special education, the curriculum guide offers information on planning a health education program for educable mentally retarded children in intermediate grades. Sections preceding the actual guide include information on specific goals of and elements necessary for a successful health education program,…

  10. Health Education for Special Children: Intermediate TMR.

    ERIC Educational Resources Information Center

    Brodie, Patrick; And Others

    Intended for teachers and administrators in special education, the curriculum guide offers information on planning a health education program for trainable mentally handicapped children in intermediate grades. Sections preceding the actual guide include information on specific goals of and elements necessary for a successful health education…

  11. Korean Intermediate Course. Selected Newspaper Articles.

    ERIC Educational Resources Information Center

    Defense Language Inst., Washington, DC.

    The purpose of this material is to provide reading matter for the last phase of the Defense Language Institute's extended and intermediate courses in Korean. (See ED 024 943 for the Korean Basic Course, Lesson Units 1-112.) The content of this volume is current, introduces important vocabulary not encountered elsewhere in the courses, and calls…

  12. Changes to the Intermediate Accounting Course Sequence

    ERIC Educational Resources Information Center

    Davidson, Lesley H.; Francisco, William H.

    2009-01-01

    There is an ever-growing amount of information that must be covered in Intermediate Accounting courses. Due to recent accounting standards and the implementation of IFRS this trend is likely to continue. This report incorporates the results of a recent survey to examine the trend of spending more course time to cover this additional material.…

  13. 49 CFR 568.5 - Requirements for intermediate manufacturers.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 6 2010-10-01 2010-10-01 false Requirements for intermediate manufacturers. 568.5...-ALL INCOMPLETE, INTERMEDIATE AND FINAL-STAGE MANUFACTURERS OF VEHICLES MANUFACTURED IN TWO OR MORE STAGES § 568.5 Requirements for intermediate manufacturers. Each intermediate manufacturer of a...

  14. Association of lipid profile and waist circumference as cardiovascular risk factors for overweight and obesity among school children in Qatar

    PubMed Central

    Rizk, Nasser M; Yousef, Mervat

    2012-01-01

    Background Childhood obesity is a national as well as worldwide problem. The aim of this study was to evaluate the association of overweight and obesity among Qatari children with lipid profile and waist circumference as adverse cardiovascular risk factors in children aged 6–11 years. International Obesity Task Force reference values were used to screen for overweight and obesity. Methods A cross-sectional study in a randomly selected sample was conducted in 315 Qatari primary school students aged 6–11 years. Anthropometric measurements, including body weight, height, waist circumference, and body mass index were calculated for 151 girls and 164 boys. Weight categories were based on International Obesity Task Force reference values. Fasting blood glucose, total cholesterol, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglycerides were measured, and atherogenic index was calculated. Results In total, 31.71% of boys and 32.78% of girls were overweight or obese. Overweight and obese children screened against International Obesity Task Force reference values had a significantly increased risk of high waist circumference (P < 0.0001), hypertriglyceridemia (P = 0.002), low HDL-C (P = 0.017), and atherogenic index (P = 0.021) compared with children who were not overweight or obese. The partial correlation coefficient for the cardiovascular risk marker of waist circumference indicated a positive significant association with total cholesterol (r = 0.465, P = 0.003), triglycerides (r = 0.563, P < 0.001), and LDL-C (r = 0.267, P = 0.003), and a significant negative association with HDL-C (r = −0.361, P = 0.004). Overweight and obesity significantly increase the odds ratios (ORs) and 95% confidence interval (CIs) of cardiovascular risk factors as follows: hypertriglyceridemia (OR 6.34, CI 2.49–13.44, P < 0.0001); LDL-C (OR 3.18, CI 1.04–9.75, P = 0.043); hypercholesterolemia (OR 1.88, CI 1.10–3.19, P = 0.020); and

  15. [Elementary Career Education Units: Intermediate Educable.

    ERIC Educational Resources Information Center

    Radford City Schools, VA.

    The guide is one of a series developed in a pilot project to integrate career education concepts with traditional subject matter and topics in elementary grades K-7 and in special education. Developed by teachers in the Radford, Virginia, schools, the units make use of resource persons from outside the school, occupational information,…

  16. Intermediates and kinetics of membrane fusion.

    PubMed Central

    Bentz, J

    1992-01-01

    Recently, it has become clear that the influenza virus fusion protein, hemagglutinin (HA), produces membrane destabilization and fusion by a multistep process, which involves the aggregation of the HAs to form a fusion site. While the details of this process are under debate, it is important to recognize that proposing any sequence of "microscopic" fusion intermediates encumbers general "macroscopic" kinetic consequences, i.e., with respect to membrane mixing rates. Using a kinetic scheme which incorporates the essential elements of several recently proposed models, some of these measurable properties have been elucidated. First, a rigorous mathematical relationship between fusion intermediates and the fusion event itself is defined. Second, it is shown that what is measured as the macroscopic "fusion rate constant" is a simple function of all of the rate constants governing the transitions between intermediates, whether or not one of the microscopic steps is rate limiting. Third, while this kinetic scheme predicts a delay (or lag) time for fusion, as has been observed, it will be very difficult to extract reliable microscopic information from these data. Furthermore, it is predicted that the delay time can depend upon HA surface density even when the HA aggregation step is very rapid compared with fusion, i.e., the delay time need not be due to HA aggregation. Fourth, the inactivation process observed for influenza virions at low pH can be described within this kinetic scheme simply, yet rigorously, via the loss of the fusion intermediates. Fifth, predicted Arrhenius plots of fusion rates can be linear for this multistep scheme, even though there is no single rate-determining step and even when a branched step is introduced, i.e., where one pathway predominates at low temperature and the other pathway predominates at high temperature. Furthermore, the apparent activation energies obtained from these plots bear little or no quantitative resemblance to the

  17. Isoporphyrin Intermediate in Heme Oxygenase Catalysis

    PubMed Central

    Evans, John P.; Niemevz, Fernando; Buldain, Graciela; de Montellano, Paul Ortiz

    2008-01-01

    Human heme oxygenase-1 (hHO-1) catalyzes the O2- and NADPH-dependent oxidation of heme to biliverdin, CO, and free iron. The first step involves regiospecific insertion of an oxygen atom at the α-meso carbon by a ferric hydroperoxide and is predicted to proceed via an isoporphyrin π-cation intermediate. Here we report spectroscopic detection of a transient intermediate during oxidation by hHO-1 of α-meso-phenylheme-IX, α-meso-(p-methylphenyl)-mesoheme-III, and α-meso-(p-trifluoromethylphenyl)-mesoheme-III. In agreement with previous experiments (Wang, J., Niemevz, F., Lad, L., Huang, L., Alvarez, D. E., Buldain, G., Poulos, T. L., and Ortiz de Montellano, P. R. (2004) J. Biol. Chem. 279, 42593–42604), only the α-biliverdin isomer is produced with concomitant formation of the corresponding benzoic acid. The transient intermediate observed in the NADPH-P450 reductase-catalyzed reaction accumulated when the reaction was supported by H2O2 and exhibited the absorption maxima at 435 and 930 nm characteristic of an isoporphyrin. Product analysis by reversed phase high performance liquid chromatography and liquid chromatography electrospray ionization mass spectrometry of the product generated with H2O2 identified it as an isoporphyrin that, on quenching, decayed to benzoylbiliverdin. In the presence of H218O2, one labeled oxygen atom was incorporated into these products. The hHO-1-isoporphyrin complexes were found to have half-lives of 1.7 and 2.4 h for the p-trifluoromethyl- and p-methyl-substituted phenylhemes, respectively. The addition of NADPH-P450 reductase to the H2O2-generated hHO-1-isoporphyrin complex produced α-biliverdin, confirming its role as a reaction intermediate. Identification of an isoporphyrin intermediate in the catalytic sequence of hHO-1, the first such intermediate observed in hemoprotein catalysis, completes our understanding of the critical first step of heme oxidation. PMID:18487208

  18. The intermediate disturbance hypothesis should be abandoned.

    PubMed

    Fox, Jeremy W

    2013-02-01

    A leading idea about how disturbances and other environmental fluctuations affect species diversity is the intermediate disturbance hypothesis (IDH). The IDH states that diversity of competing species is, or should be expected to be, maximized at intermediate frequencies and/or intensities of disturbance or environmental change. I argue that the IDH has been refuted on both empirical and theoretical grounds, and so should be abandoned. Empirical studies only rarely find the predicted humped diversity-disturbance relationship. Theoretically, the three major mechanisms thought to produce humped diversity-disturbance relationships are logically invalid and do not actually predict what they are thought to predict. Disturbances and other environmental fluctuations can affect diversity, but for different reasons than are commonly recognized. Copyright © 2012 Elsevier Ltd. All rights reserved.

  19. Substrate Activation by Iron Superoxo Intermediates

    PubMed Central

    van der Donk, Wilfred A.; Krebs, Carsten; Bollinger, J. Martin

    2010-01-01

    A growing number of non-heme-iron oxygenases and oxidases catalyze reactions for which the well-established mechanistic paradigm involving a single C-H-bond cleaving intermediate of the Fe(IV)-oxo (ferryl) type [1] is insufficient to explain the chemistry. It is becoming clear that, in several of these cases, Fe(III)-superoxide complexes formed by simple addition of O2 to the reduced [Fe(II)] cofactor initiate substrate oxidation by abstracting hydrogen [2]. This substrate-oxidizing entry route into high-valent-iron intermediates makes possible an array of complex and elegant oxidation reactions without consumption of valuable reducing equivalents. Examples of this novel mechanistic strategy are discussed with the goal of bringing forth unifying principles. PMID:20951572

  20. Colloidal Nanoparticles for Intermediate Band Solar Cells

    SciTech Connect

    Vörös, Márton; Galli, Giulia; Zimanyi, Gergely T.

    2015-07-28

    The Intermediate Band (IB) solar cell concept is a promising idea to transcend the Shockley–Queisser limit. Using the results of first-principles calculations, we propose that colloidal nanoparticles (CNPs) are a viable and efficient platform for the implementation of the IB solar cell concept. We focused on CdSe CNPs and we showed that intragap states present in the isolated CNPs with reconstructed surfaces combine to form an IB in arrays of CNPs, which is well separated from the valence and conduction band edges. We demonstrated that optical transitions to and from the IB are active. We also showed that the IB can be electron doped in a solution, e.g., by decamethylcobaltocene, thus activating an IB-induced absorption process. Our results, together with the recent report of a nearly 10% efficient CNP solar cell, indicate that colloidal nanoparticle intermediate band solar cells are a promising platform to overcome the Shockley–Queisser limit.

  1. Intermediate Temperature Water Heat Pipe Tests

    NASA Technical Reports Server (NTRS)

    Devarakonda, Angirasa; Xiong, Daxi; Beach, Duane E.

    2004-01-01

    Heat pipes are among the most promising technologies for space radiator systems. Water heat pipes are explored in the intermediate temperature range of 400 to above 500 K. The thermodynamic and thermo-physical properties of water are reviewed in this temperature range. Test Data are reported for a copper-water heat pipe. The heat pipe was tested under different orientations. Water heat pipes show promise in this temperature range.Fabrication and testing issues are being addressed.

  2. Intermediate Temperature Water Heat Pipe Tests

    NASA Technical Reports Server (NTRS)

    Devarakonda, Angirasa; Xiong, Da-Xi; Beach, Duane E.

    2005-01-01

    Heat pipes are among the most promising technologies for space radiator systems. Water heat pipes are explored in the intermediate temperature range of 400 to above 500 K. The thermodynamic and thermo-physical properties of water are reviewed in this temperature range. Test data are reported for a copper-water heat pipe. The heat pipe was tested under different orientations. Water heat pipes show promise in this temperature range. Fabrication and testing issues are being addressed.

  3. Dwarf nova outbursts in intermediate polars

    NASA Astrophysics Data System (ADS)

    Hameury, J.-M.; Lasota, J.-P.

    2017-06-01

    Context. The disc instability model (DIM) has been very successful in explaining the dwarf nova outbursts observed in cataclysmic variables. When, as in intermediate polars, the accreting white dwarf is magnetised, the disc is truncated at the magnetospheric radius, but for mass-transfer rates corresponding to the thermal-viscous instability such systems should still exhibit dwarf-nova outbursts. Yet, the majority of intermediate polars, in which the magnetic field is not large enough to completely disrupt the accretion disc, seem to be stable, and the rare observed outbursts, in particular in systems with long orbital periods, are much shorter than normal dwarf-nova outbursts. Aims: We investigate the predictions of the disc instability model for intermediate polars in order to determine which of the observed properties of these systems can be explained by the DIM. Methods: We use our numerical code for the time evolution of accretion discs, modified to include the effects of the magnetic field, with constant or variable mass transfer from the secondary star. Results: We show that intermediate polars have mass transfer low enough and magnetic fields large enough to keep the accretion disc stable on the cold equilibrium branch. We show that the infrequent and short outbursts observed in long-period systems, such as, for example, TV Col, cannot be attributed to the thermal-viscous instability of the accretion disc, but instead have to be triggered by an enhanced mass-transfer from the secondary, or, more likely, by some instability coupling the white dwarf magnetic field with that generated by the magnetorotational instability operating in the accretion disc. Longer outbursts (a few days) could result from the disc instability.

  4. Warm-intermediate inflationary universe model

    SciTech Connect

    Campo, Sergio del; Herrera, Ramon E-mail: ramon.herrera@ucv.cl

    2009-04-15

    Warm inflationary universe models in the context of intermediate expansion, between power law and exponential, are studied. General conditions required for these models to be realizable are derived and discussed. This study is done in the weak and strong dissipative regimes. The inflaton potentials considered in this study are negative-power-law and powers of logarithms, respectively. The parameters of our models are constrained from the WMAP three and five year data.

  5. Radicals: Reactive Intermediates with Translational Potential

    PubMed Central

    2016-01-01

    This Perspective illustrates the defining characteristics of free radical chemistry, beginning with its rich and storied history. Studies from our laboratory are discussed along with recent developments emanating from others in this burgeoning area. The practicality and chemoselectivity of radical reactions enable rapid access to molecules of relevance to drug discovery, agrochemistry, material science, and other disciplines. Thus, these reactive intermediates possess inherent translational potential, as they can be widely used to expedite scientific endeavors for the betterment of humankind. PMID:27631602

  6. The Influence of Soviet and American Political Culture on Negotiating Positions: The Intermediate-Range Nuclear Force Case.

    DTIC Science & Technology

    1984-03-01

    AD-Ri42 990 THE INFLUENCE OF SOVIET AND AMERICAN POLITICAL CULTURE 1/2 ON~ NEGOTIATING POS..(U) NAVAL POSTGRADUATE SCHOOL MONTEREY CA W R BLACKBURN...SCHOOL Monterey, California DTIC 0f JUL1 3ŕ H THESIS THE INFLUENCE OF SOVIET AND AMERICAN POLITICA CULTURE ON NEGOTIATING POSITIONS: THE INTERMEDIATE...4. TITL.E (and Sublto) S. TYPE[ OF REPORT & PERIOD COVERED The Influence of Soviet and American Master’s Thesis Political Culture on Negotiating

  7. The middle of the road: perceiving intermediates.

    PubMed

    Bianchi, Ivana; Burro, Roberto; Torquati, Stefania; Savardi, Ugo

    2013-09-01

    This article aims to study the extension and immediacy of the perception of intermediates during the observation of images showing a variation in a spatial property from one extreme (e.g. at the top of a mountain) to the opposite extreme (e.g. at the bottom of a mountain). Three experiments were carried out: rating tasks were used in studies 1 and 3 and a classification task in study 2. Three main results emerged. The first result (concerning extension) is that people consistently recognize some instances of a dimension as intermediates (neither a… nor b) rather than as one or the other opposite pole (a, b). The number of these cases ranges from one to most of the experiences in between the two extremes, depending on the type of opposite considered. The second result (concerning immediacy) is that recognizing and rating intermediates did not take longer in most cases than recognizing and rating the two poles. The third result (concerning task influence) is that there were differences due to the type of task, i.e. rating and classification. The implications of these results are discussed within the framework of theories grounding cognition in perception.

  8. Reactive Nitrogen Intermediates in Giant Cell Arteritis

    PubMed Central

    Borkowski, Astrid; Younge, Brian R.; Szweda, Luke; Mock, Bettina; Björnsson, Johannes; Moeller, Kerstin; Goronzy, Jörg J.; Weyand, Cornelia M.

    2002-01-01

    Arterial wall damage in giant cell arteritis (GCA) is mediated by several different macrophage effector functions, including the production of metalloproteinases and lipid peroxidation. Tissue-invading macrophages also express nitric oxide synthase (NOS)-2, but it is not known whether nitric oxide-related mechanisms contribute to the disease process. Nitric oxide can form nitrating agents, including peroxynitrite, a nitric oxide congener formed in the presence of reactive oxygen intermediates. Protein nitration selectively targets tyrosine residues and can result in a gain, as well as a loss, of protein function. Nitrated tyrosine residues in GCA arteries were detected almost exclusively on endothelial cells of newly formed microcapillaries in the media, whereas microvessels in the adventitia and the intima were spared. Nitration correlated with endothelial NOS-3 expression and not with NOS-2-producing macrophages, which preferentially homed to the hyperplastic intima. The restriction of nitration to the media coincided with the production of reactive oxygen intermediates as demonstrated by the presence of the toxic aldehyde, 4-hydroxynonenal. Depletion of tissue-infiltrating macrophages in human temporal artery-SCID mouse chimeras disrupted nitrotyrosine generation, demonstrating a critical role of macrophages in the nitration process that targeted medial microvessels. Thus, protein nitration in GCA is highly compartmentalized, reflecting the production of reactive oxygen and reactive nitrogen intermediates in the inflamed arterial wall. Heterogeneity of microvessels in NOS-3 regulation may be an additional determinant contributing to this compartmentalization and could explain the preferential targeting of newly generated capillary beds. PMID:12107096

  9. Diffraction of electrons at intermediate energies

    NASA Astrophysics Data System (ADS)

    Ascolani, H.; Barrachina, R. O.; Guraya, M. M.; Zampieri, G.

    1992-08-01

    We present a theory of the elastic scattering of electrons from crystalline surfaces that contains both low-energy-electron-diffraction (LEED) effects at low energies and x-ray-photoelectron- and Auger-electron-diffraction (XPD/AED) effects at intermediate energies. The theory is based on a cluster-type approach to the scattering problem and includes temperature effects. The transition from one regime to the other may be explained as follows: At low energies all the scattered waves add coherently, and the intensity is dominated by LEED effects. At intermediate energies the thermal vibration of the atoms destroys the long-range coherency responsible for the LEED peaks, but affects little the interference of those waves that share parts of their paths inside the solid. Thus, the interference of these waves comes to dominate the intensity, giving rise to structures similar to those observed in XPD/AED experiments. We perform a calculation of the elastic reflection of electrons from Cu(001) that is in good agreement with the experiment in the range 200-1500 eV. At low energies the intensity is dominated by LEED peaks; at 400 eV LEED peaks and XPD/AED structures coexist; and above this energy the intensity is dominated by the latter. We analyze the contributions to the intensity at intermediate energies of the interferences in the incoming and outgoing parts of the electron path.

  10. Epigenetic regulation of transcription in intermediate heterochromatin.

    PubMed

    Habu, Yoshiki; Mathieu, Olivier; Tariq, Muhammad; Probst, Aline V; Smathajitt, Chotika; Zhu, Tong; Paszkowski, Jerzy

    2006-12-01

    Constitutive heterochromatin is a compact, transcriptionally inert structure formed in gene-poor and repeat- and transposon-rich regions. In Arabidopsis, constitutive heterochromatin is characterized by hypermethylated DNA and histone H3 dimethylated at lysine (K) 9 (H3K9me2) together with depletion of histone H3 dimethylated at lysine 4 (H3K4me2). Here, we describe loci with intermediate properties of heterochromatin in which transcription downregulation is inherited in a manner similar to constitutive heterochromatin, although the loci are associated with opposing histone marks--H3K4me2 and H3K9me2. In the ddm1 (decrease in DNA methylation 1) mutants, their transcriptional activation is accompanied by the expected shift in the H3 modifications--depletion of H3K9me2 and enrichment in H3K4me2. In mom1 (Morpheus' molecule 1) mutants, however, a marked increase in transcription is not accompanied by detectable changes in the levels of H3K4me2 and H3K9me2. Therefore, transcriptional regulation in the intermediate heterochromatin involves two distinct epigenetic mechanisms. Interestingly, silent transgenic inserts seem to acquire properties characteristic of the intermediate heterochromatin.

  11. Report to the Vincent Astor Foundation; New York/London Middle School Conference.

    ERIC Educational Resources Information Center

    New York Urban Coalition, NY.

    The New York-London Middle Schools Project of 1976 provided an opportunity for a representative group of London educators to study New York City's public school system in terms of school community relations, school based planning and staff development at the junior high/intermediate school level. In this report, British educators provide a brief…

  12. Determining the Demographic Profiles of Middle School Students Receiving Two Counseling Services

    ERIC Educational Resources Information Center

    Pechersky, Kara

    2009-01-01

    This study investigated the demographic profiles of middle school students receiving either singular school-based mental health services or bundled school-based mental health services in conjunction with school counseling services. Demographic variables collected for this study characterize students attending six intermediate or middle-schools,…

  13. 34 CFR 200.17 - Intermediate goals.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... by the timeline under § 200.15 as follows: (a) The first incremental increase must take effect not later than the 2004-2005 school year. (b) Each following incremental increase must occur in not more...

  14. Synthetic mononuclear nonheme iron-oxygen intermediates.

    PubMed

    Nam, Wonwoo

    2015-08-18

    Mononuclear nonheme iron-oxygen species, such as iron-superoxo, -peroxo, -hydroperoxo, and -oxo, are key intermediates involved in dioxygen activation and oxidation reactions catalyzed by nonheme iron enzymes. Because these iron-oxygen intermediates are short-lived due to their thermal instability and high reactivity, it is challenging to investigate their structural and spectroscopic properties and reactivity in the catalytic cycles of the enzymatic reactions themselves. One way to approach such problems is to synthesize biomimetic iron-oxygen complexes and to tune their geometric and electronic structures for structural characterization and reactivity studies. Indeed, a number of biologically important iron-oxygen species, such as mononuclear nonheme iron(III)-superoxo, iron(III)-peroxo, iron(III)-hydroperoxo, iron(IV)-oxo, and iron(V)-oxo complexes, were synthesized recently, and the first X-ray crystal structures of iron(III)-superoxo, iron(III)-peroxo, and iron(IV)-oxo complexes in nonheme iron models were successfully obtained. Thus, our understanding of iron-oxygen intermediates in biological reactions has been aided greatly from the studies of the structural and spectroscopic properties and the reactivities of the synthetic biomimetic analogues. In this Account, we describe our recent results on the synthesis and characterization of mononuclear nonheme iron-oxygen complexes bearing simple macrocyclic ligands, such as N-tetramethylated cyclam ligand (TMC) and tetraamido macrocyclic ligand (TAML). In the case of iron-superoxo complexes, an iron(III)-superoxo complex, [(TAML)Fe(III)(O2)](2-), is described, including its crystal structure and reactivities in electrophilic and nucleophilic oxidative reactions, and its properties are compared with those of a chromium(III)-superoxo complex, [(TMC)Cr(III)(O2)(Cl)](+), with respect to its reactivities in hydrogen atom transfer (HAT) and oxygen atom transfer (OAT) reactions. In the case of iron-peroxo intermediates

  15. Intermediate DNA methylation is a conserved signature of genome regulation

    PubMed Central

    Elliott, GiNell; Hong, Chibo; Xing, Xiaoyun; Zhou, Xin; Li, Daofeng; Coarfa, Cristian; Bell, Robert J.A.; Maire, Cecile L.; Ligon, Keith L.; Sigaroudinia, Mahvash; Gascard, Philippe; Tlsty, Thea D.; Harris, R. Alan; Schalkwyk, Leonard C.; Bilenky, Misha; Mill, Jonathan; Farnham, Peggy J.; Kellis, Manolis; Marra, Marco A.; Milosavljevic, Aleksandar; Hirst, Martin; Stormo, Gary D.; Wang, Ting; Costello, Joseph F.

    2015-01-01

    The role of intermediate methylation states in DNA is unclear. Here, to comprehensively identify regions of intermediate methylation and their quantitative relationship with gene activity, we apply integrative and comparative epigenomics to 25 human primary cell and tissue samples. We report 18,452 intermediate methylation regions located near 36% of genes and enriched at enhancers, exons and DNase I hypersensitivity sites. Intermediate methylation regions average 57% methylation, are predominantly allele-independent and are conserved across individuals and between mouse and human, suggesting a conserved function. These regions have an intermediate level of active chromatin marks and their associated genes have intermediate transcriptional activity. Exonic intermediate methylation correlates with exon inclusion at a level between that of fully methylated and unmethylated exons, highlighting gene context-dependent functions. We conclude that intermediate DNA methylation is a conserved signature of gene regulation and exon usage. PMID:25691127

  16. A new intermediate for the production of flexible stable polymers

    NASA Technical Reports Server (NTRS)

    Webster, J. A.

    1973-01-01

    Method of incorporating ether linkages into perfluoroalkylene segment of a dianydride intermediate yields intermediate that may be used in synthesis of flexible, stable polyimides for use as high-temperature, solvent-resistant sealants.

  17. Extrasolar planets around intermediate mass stars

    NASA Astrophysics Data System (ADS)

    Hatzes, A. P.

    2008-08-01

    One of the earliest hints for extrasolar planets came with the discovery almost 15 years ago of low amplitude, long period radial velocity (RV) variations in several K giant stars, β Gem, α Tau (Aldebaran) and α Boo. Since then it has been confirmed that for β Gem (stellar mass =1.7 Modot) these RV variations are due to a planetary companion. Aldebaran is another K giant star showing long-lived (>26 years) and coherent RV variations. These are most likely due to a planetary companion having a mass of 9 MJup using an estimated mass of 2.5 Modot for the star. Giant stars like α Tau and β Gem offer us the possibility of studying the process of planet formation around stars more massive than the sun. The main sequence stars with masses >1.2 Modot are ill-suited for RV surveys as there are few spectral lines for measuring the RV and these are often broadened by high rates of stellar rotation. Currently over 20 intermediate mass giant stars are known to host extrasolar planets. This sample is sufficiently large that we can begin to look at the overall properties of planets around intermediate mass stars. These suggest that more massive stars may have more massive planets that the orbital eccentricities for their extrasolar planets show the wide range of eccentricities seen for main sequence, solar mass stars, and that unlike for main sequence stars there seems to be no preference for metal rich intermediate mass stars to host extrasolar planets.

  18. Intermediate temperature solid oxide fuel cells.

    PubMed

    Brett, Daniel J L; Atkinson, Alan; Brandon, Nigel P; Skinner, Stephen J

    2008-08-01

    High temperature solid oxide fuel cells (SOFCs), typified by developers such as Siemens Westinghouse and Rolls-Royce, operate in the temperature region of 850-1000 degrees C. For such systems, very high efficiencies can be achieved from integration with gas turbines for large-scale stationary applications. However, high temperature operation means that the components of the stack need to be predominantly ceramic and high temperature metal alloys are needed for many balance-of-plant components. For smaller scale applications, where integration with a heat engine is not appropriate, there is a trend to move to lower temperatures of operation, into the so-called intermediate temperature (IT) range of 500-750 degrees C. This expands the choice of materials and stack geometries that can be used, offering reduced system cost and, in principle, reducing the corrosion rate of stack and system components. This review introduces the IT-SOFC and explains the advantages of operation in this temperature regime. The main advances made in materials chemistry that have made IT operation possible are described and some of the engineering issues and the new opportunities that reduced temperature operation affords are discussed. This tutorial review examines the advances being made in materials and engineering that are allowing solid oxide fuel cells to operate at lower temperature. The challenges and advantages of operating in the so-called 'intermediate temperature' range of 500-750 degrees C are discussed and the opportunities for applications not traditionally associated with solid oxide fuel cells are highlighted. This article serves as an introduction for scientists and engineers interested in intermediate temperature solid oxide fuel cells and the challenges and opportunities of reduced temperature operation.

  19. Intermediate Temperature Solid Oxide Fuel Cell Development

    SciTech Connect

    S. Elangovan; Scott Barnett; Sossina Haile

    2008-06-30

    Solid oxide fuel cells (SOFCs) are high efficiency energy conversion devices. Present materials set, using yttria stabilized zirconia (YSZ) electrolyte, limit the cell operating temperatures to 800 C or higher. It has become increasingly evident however that lowering the operating temperature would provide a more expeditious route to commercialization. The advantages of intermediate temperature (600 to 800 C) operation are related to both economic and materials issues. Lower operating temperature allows the use of low cost materials for the balance of plant and limits degradation arising from materials interactions. When the SOFC operating temperature is in the range of 600 to 700 C, it is also possible to partially reform hydrocarbon fuels within the stack providing additional system cost savings by reducing the air preheat heat-exchanger and blower size. The promise of Sr and Mg doped lanthanum gallate (LSGM) electrolyte materials, based on their high ionic conductivity and oxygen transference number at the intermediate temperature is well recognized. The focus of the present project was two-fold: (a) Identify a cell fabrication technique to achieve the benefits of lanthanum gallate material, and (b) Investigate alternative cathode materials that demonstrate low cathode polarization losses at the intermediate temperature. A porous matrix supported, thin film cell configuration was fabricated. The electrode material precursor was infiltrated into the porous matrix and the counter electrode was screen printed. Both anode and cathode infiltration produced high performance cells. Comparison of the two approaches showed that an infiltrated cathode cells may have advantages in high fuel utilization operations. Two new cathode materials were evaluated. Northwestern University investigated LSGM-ceria composite cathode while Caltech evaluated Ba-Sr-Co-Fe (BSCF) based pervoskite cathode. Both cathode materials showed lower polarization losses at temperatures as low as 600

  20. Nitrene Radical Intermediates in Catalytic Synthesis.

    PubMed

    Kuijpers, Petrus; van der Vlugt, Jarl Ivar; Schneider, Sven; de Bruin, Bas

    2017-07-04

    Nitrene radical complexes are reactive intermediates with discrete spin density at the nitrogen-atom of the nitrene moiety. These species have become important intermediates for organic synthesis, being invoked in a broad range of C-H functionalization and aziridination reactions. Nitrene radical complexes have intriguing electronic structures, and are best described as one-electron reduced Fischer-type nitrenes. They can be generated by intramolecular single electron transfer to the 'redox non-innocent' nitrene moiety at the metal. Nitrene radicals generated at open-shell cobalt(II) have thus far received most attention in terms of spectroscopic characterization, reactivity screening, catalytic application and (computational and experimental) mechanistic studies, but some interesting iron and precious metal catalysts have also been employed in related reactions involving nitrene radicals. In some cases, redox-active ligands are used to facilitate intramolecular single electron transfer from the complex to the nitrene moiety. Organic azides are among the most attractive nitrene precursors in this field, typically requiring pre-activated organic azides (e.g. RSO2N3, (RO)2P(=O)N3, ROC(=O)N3 and alike) to achieve efficient and selective catalysis. Challenging, non-activated aliphatic organic azides were recently added to the palette of synthetically useful reactions proceeding via nitrene radical intermediates. This concept article describes the electronic structure of nitrene radical complexes, emphasizes on their usefulness in the catalytic synthesis of various organic products, and highlights the important developments in the field. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  1. Intermediate filaments: from cell architecture to nanomechanics.

    PubMed

    Herrmann, Harald; Bär, Harald; Kreplak, Laurent; Strelkov, Sergei V; Aebi, Ueli

    2007-07-01

    Intermediate filaments (IFs) constitute a major structural element of animal cells. They build two distinct systems, one in the nucleus and one in the cytoplasm. In both cases, their major function is assumed to be that of a mechanical stress absorber and an integrating device for the entire cytoskeleton. In line with this, recent disease mutations in human IF proteins indicate that the nanomechanical properties of cell-type-specific IFs are central to the pathogenesis of diseases as diverse as muscular dystrophy and premature ageing. However, the analysis of these various diseases suggests that IFs also have an important role in cell-type-specific physiological functions.

  2. Reactive intermediates in cytochrome p450 catalysis.

    PubMed

    Krest, Courtney M; Onderko, Elizabeth L; Yosca, Timothy H; Calixto, Julio C; Karp, Richard F; Livada, Jovan; Rittle, Jonathan; Green, Michael T

    2013-06-14

    Recently, we reported the spectroscopic and kinetic characterizations of cytochrome P450 compound I in CYP119A1, effectively closing the catalytic cycle of cytochrome P450-mediated hydroxylations. In this minireview, we focus on the developments that made this breakthrough possible. We examine the importance of enzyme purification in the quest for reactive intermediates and report the preparation of compound I in a second P450 (P450ST). In an effort to bring clarity to the field, we also examine the validity of controversial reports claiming the production of P450 compound I through the use of peroxynitrite and laser flash photolysis.

  3. Intermediate Bandgap Solar Cells From Nanostructured Silicon

    SciTech Connect

    Black, Marcie

    2014-10-30

    This project aimed to demonstrate increased electronic coupling in silicon nanostructures relative to bulk silicon for the purpose of making high efficiency intermediate bandgap solar cells using silicon. To this end, we formed nanowires with controlled crystallographic orientation, small diameter, <111> sidewall faceting, and passivated surfaces to modify the electronic band structure in silicon by breaking down the symmetry of the crystal lattice. We grew and tested these silicon nanowires with <110>-growth axes, which is an orientation that should produce the coupling enhancement.

  4. Thermoelectric power generator with intermediate loop

    SciTech Connect

    Bell, Lon E; Crane, Douglas Todd

    2013-05-21

    A thermoelectric power generator is disclosed for use to generate electrical power from heat, typically waste heat. An intermediate heat transfer loop forms a part of the system to permit added control and adjustability in the system. This allows the thermoelectric power generator to more effectively and efficiently generate power in the face of dynamically varying temperatures and heat flux conditions, such as where the heat source is the exhaust of an automobile, or any other heat source with dynamic temperature and heat flux conditions.

  5. Thermoelectric power generator with intermediate loop

    DOEpatents

    Bel,; Lon, E [Altadena, CA; Crane, Douglas Todd [Pasadena, CA

    2009-10-27

    A thermoelectric power generator is disclosed for use to generate electrical power from heat, typically waste heat. An intermediate heat transfer loop forms a part of the system to permit added control and adjustability in the system. This allows the thermoelectric power generator to more effectively and efficiently generate power in the face of dynamically varying temperatures and heat flux conditions, such as where the heat source is the exhaust of an automobile, or any other heat source with dynamic temperature and heat flux conditions.

  6. Ligand Intermediates in Metal-Catalyzed Reactions

    SciTech Connect

    Gladysz, John A.

    1999-07-31

    The longest-running goal of this project has been the synthesis, isolation, and physical chemical characterization of homogeneous transition metal complexes containing ligand types believed to be intermediates in the metal-catalyzed conversion of CO/H{sub 2}, CO{sub 2}, CH{sub 4}, and similar raw materials to organic fuels, feedstocks, etc. In the current project period, complexes that contain unusual new types of C{sub x}(carbide) and C{sub x}O{sub y} (carbon oxide) ligands have been emphasized. A new program in homogeneous fluorous phase catalysis has been launched as described in the final report.

  7. Order and disorder in intermediate filament proteins.

    PubMed

    Kornreich, Micha; Avinery, Ram; Malka-Gibor, Eti; Laser-Azogui, Adi; Beck, Roy

    2015-09-14

    Intermediate filaments (IFs), important components of the cytoskeleton, provide a versatile, tunable network of self-assembled proteins. IF proteins contain three distinct domains: an α-helical structured rod domain, flanked by intrinsically disordered head and tail domains. Recent studies demonstrated the functional importance of the disordered domains, which differ in length and amino-acid sequence among the 70 different human IF genes. Here, we investigate the biophysical properties of the disordered domains, and review recent findings on the interactions between them. Our analysis highlights key components governing IF functional roles in the cytoskeleton, where the intrinsically disordered domains dictate protein-protein interactions, supramolecular assembly, and macro-scale order.

  8. MHD oxidant intermediate temperature ceramic heater study

    NASA Technical Reports Server (NTRS)

    Carlson, A. W.; Chait, I. L.; Saari, D. P.; Marksberry, C. L.

    1981-01-01

    The use of three types of directly fired ceramic heaters for preheating oxygen enriched air to an intermediate temperature of 1144K was investigated. The three types of ceramic heaters are: (1) a fixed bed, periodic flow ceramic brick regenerative heater; (2) a ceramic pebble regenerative heater. The heater design, performance and operating characteristics under conditions in which the particulate matter is not solidified are evaluated. A comparison and overall evaluation of the three types of ceramic heaters and temperature range determination at which the particulate matter in the MHD exhaust gas is estimated to be a dry powder are presented.

  9. Reactive Intermediates in Cytochrome P450 Catalysis*

    PubMed Central

    Krest, Courtney M.; Onderko, Elizabeth L.; Yosca, Timothy H.; Calixto, Julio C.; Karp, Richard F.; Livada, Jovan; Rittle, Jonathan; Green, Michael T.

    2013-01-01

    Recently, we reported the spectroscopic and kinetic characterizations of cytochrome P450 compound I in CYP119A1, effectively closing the catalytic cycle of cytochrome P450-mediated hydroxylations. In this minireview, we focus on the developments that made this breakthrough possible. We examine the importance of enzyme purification in the quest for reactive intermediates and report the preparation of compound I in a second P450 (P450ST). In an effort to bring clarity to the field, we also examine the validity of controversial reports claiming the production of P450 compound I through the use of peroxynitrite and laser flash photolysis. PMID:23632017

  10. 29 CFR 452.81 - Rights in intermediate body elections.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 2 2013-07-01 2013-07-01 false Rights in intermediate body elections. 452.81 Section 452... REPORTING AND DISCLOSURE ACT OF 1959 Campaign Safeguards § 452.81 Rights in intermediate body elections... apply to intermediate bodies. 42 The Department of Labor considers these rulings to be consistent with...

  11. Institutionalized Crucible Experiences within Intermediate-Level Education

    DTIC Science & Technology

    2015-06-12

    INSTITUTIONALIZED CRUCIBLE EXPERIENCES WITHIN INTERMEDIATE-LEVEL EDUCATION A thesis presented to the Faculty of the U.S...TITLE AND SUBTITLE Institutionalized Crucible Experiences within Intermediate-Level Education 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c...effects, both positive and negative, of implementing a crucible experience within Intermediate-Level Education across all military services within the

  12. 14 CFR 398.8 - Number of intermediate stops.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Number of intermediate stops. 398.8 Section 398.8 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION... Number of intermediate stops. (a) Except in Alaska, no more than one intermediate stop is permitted in...

  13. 40 CFR 86.246-94 - Intermediate temperature testing.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 19 2012-07-01 2012-07-01 false Intermediate temperature testing. 86... New Medium-Duty Passenger Vehicles; Cold Temperature Test Procedures § 86.246-94 Intermediate temperature testing. (a) This section is applicable to tests which are conducted at an intermediate...

  14. 40 CFR 86.246-94 - Intermediate temperature testing.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 19 2013-07-01 2013-07-01 false Intermediate temperature testing. 86... New Medium-Duty Passenger Vehicles; Cold Temperature Test Procedures § 86.246-94 Intermediate temperature testing. (a) This section is applicable to tests which are conducted at an intermediate...

  15. 40 CFR 86.246-94 - Intermediate temperature testing.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 18 2011-07-01 2011-07-01 false Intermediate temperature testing. 86... New Medium-Duty Passenger Vehicles; Cold Temperature Test Procedures § 86.246-94 Intermediate temperature testing. (a) This section is applicable to tests which are conducted at an intermediate...

  16. 40 CFR 86.246-94 - Intermediate temperature testing.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 18 2010-07-01 2010-07-01 false Intermediate temperature testing. 86... New Medium-Duty Passenger Vehicles; Cold Temperature Test Procedures § 86.246-94 Intermediate temperature testing. (a) This section is applicable to tests which are conducted at an intermediate...

  17. 22 CFR 140.10 - Intermediate credit institutions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Intermediate credit institutions. 140.10... TRAFFICKERS Enforcement § 140.10 Intermediate credit institutions. (a) Treatment as non-governmental entity or as a foreign government entity. Intermediate credit institutions (“ICIs”) shall be subject to either...

  18. Physics of intermediate shocks: A review

    NASA Technical Reports Server (NTRS)

    Karimabadi, H.

    1995-01-01

    Intermediate shocks (ISs) lead to a transition from super-Alfvenic to sub-Alfvenic flow and are different from slow and fast shocks in that an IS rotates the component of the magnetic field tangent to the shock plane by 180 deg. Another peculiarity of ISs is that for the same upstream conditions an IS can have two different downstream states. There also exist a second class of ISs which rotate the magnetic field by an angle other than 180 deg. Due to their noncoplanar nature they cannot be time-stationary and are referred to as time-dependent intermediate shocks (TDIS). The existence of ISs has been the subject of much controversy over the years. Early studies questioned the physical reality of ISs. However, the studies of ISs found a new impetus when C.C. Wu showed that ISs do exist and are stable within the resistive MHD framework. In this paper, after a brief historical overview of the subject, we will review the latest developments in the study of ISs. In particular, we will address the questions of stability and structure of ISs and the relationship between ISs and other discontinuities. One of the recent developments has been the finding that ISs can be unsteady, reforming in time. Details of this process will be discussed. Finally, we examine the effect of anisotropy on the resolutions and discuss the relevance of ISs to the observed field rotations at the Earth's magnetopause.

  19. Intermediate GRBs observed by various satellite experiments

    NASA Astrophysics Data System (ADS)

    Arkhangelskaja, I. V.

    2017-01-01

    Firstly GRB duration distribution was analyzed on data of BATSE experiment onboard the Compton Gamma Ray Observatory (CGRO) operated from April 1991 until to June 2000. Usually two GRBs groups separated in duration distribution: short and long. These types of events are classified due to analysis of duration of interval where integrated counts from the GRB raising from 5% to 95% (t90). The value t90 ∼ 2s is used as boundary between short and long events. However, in 1999 third burst subgroup (intermediate GRBs) was found due to GRBs duration and duration-hardness distributions analysis of 4B current BATSE catalogue (recently available as 5B one) in time interval of 0.8 s ≤ t90≤ 50 s. Since CGRO operation has finished, two satellite experiments GRBs catalogues BAT/Swift and GBM/Fermi contain the amount of bursts comparable with 4B current BATSE catalogue and it is sufficient for duration distribution precision investigation. The results of these distributions analysis are discussed. It allows concluding the appearance of intermediate GRB subgroup on data of three experiments: BATSE/CGRO, BAT/Swift and GBM/Fermi.

  20. X-rays from intermediate mass stars

    NASA Astrophysics Data System (ADS)

    Robrade, Jan

    I will review the X-ray properties of intermediate mass stars and discuss possible X-ray generating mechanisms. Main-sequence stars of spectral type mid B to mid A neither drive sufficiently strong winds to produce shock generated X-rays, nor possess an outer convection zone to generate dynamo driven magnetic activity and coronae. Consequently they should be virtually X-ray dark and occasionally detected X-ray emission was usually attributed to undetected low-mass companions. However, in magnetic intermediate mass stars, the Ap/Bp stars, a different X-ray production mechanism may operate. It is termed the magnetically channeled wind-shock model, where the stellar wind from both hemispheres is channelled towards the equatorial plane, collides and forms a rigidly rotating disk around the star. The strong shocks of the nearly head-on wind collision as well as the existence of magnetically confined plasma in a dynamic circumstellar disk can lead to diverse X-ray phenomena. In this sense Ap/Bp stars bridge the 'classical' X-ray regimes of cool and hot stars.

  1. Advanced intermediate temperature sodium copper chloride battery

    NASA Astrophysics Data System (ADS)

    Yang, Li-Ping; Liu, Xiao-Min; Zhang, Yi-Wei; Yang, Hui; Shen, Xiao-Dong

    2014-12-01

    Sodium metal chloride batteries, also called as ZEBRA batteries, possess many merits such as low cost, high energy density and high safety, but their high operation temperature (270-350 °C) may cause several issues and limit their applications. Therefore, decreasing the operation temperature is of great importance in order to broaden their usage. Using a room temperature ionic liquid (RTIL) catholyte composed of sodium chloride buffered 1-ethyl-3-methylimidazolium chloride-aluminum chloride and a dense β″-aluminates solid electrolyte film with 500 micron thickness, we report an intermediate temperature sodium copper chloride battery which can be operated at only 150 °C, therefore alleviating the corrosion issues, improving the material compatibilities and reducing the operating complexities associated with the conventional ZEBRA batteries. The RTIL presents a high ionic conductivity (0.247 S cm-1) at 150 °C and a wide electrochemical window (-2.6 to 2.18 vs. Al3+/Al). With the discharge plateau at 2.64 V toward sodium and the specific capacity of 285 mAh g-1, this intermediate temperature battery exhibits an energy density (750 mWh g-1) comparable to the conventional ZEBRA batteries (728-785 mWh g-1) and superior to commercialized Li-ion batteries (550-680 mWh g-1), making it very attractive for renewable energy integration and other grid related applications.

  2. Keto-Enol Thermodynamics of Breslow Intermediates.

    PubMed

    Paul, Mathias; Breugst, Martin; Neudörfl, Jörg-Martin; Sunoj, Raghavan B; Berkessel, Albrecht

    2016-04-20

    Breslow intermediates, first postulated in 1958, are pivotal intermediates in carbene-catalyzed umpolung. Attempts to isolate and characterize these fleeting amino enol species first met with success in 2012 when we found that saturated bis-Dipp/Mes imidazolidinylidenes readily form isolable, though reactive diamino enols with aldehydes and enals. In contrast, triazolylidenes, upon stoichiometric reaction with aldehydes, gave exclusively the keto tautomer, and no isolable enol. Herein, we present the synthesis of the "missing" keto tautomers of imidazolidinylidene-derived diamino enols, and computational thermodynamic data for 15 enol-ketone pairs derived from various carbenes/aldehydes. Electron-withdrawing substituents on the aldehyde favor enol formation, the same holds for N,N'-Dipp [2,6-di(2-propyl)phenyl] and N,N'-Mes [2,4,6-trimethylphenyl] substitution on the carbene component. The latter effect rests on stabilization of the diamino enol tautomer by Dipp substitution, and could be attributed to dispersive interaction of the 2-propyl groups with the enol moiety. For three enol-ketone pairs, equilibration of the thermodynamically disfavored tautomer was attempted with acids and bases but could not be effected, indicating kinetic inhibition of proton transfer.

  3. Intermediate energy neutron beams from the MURR.

    PubMed

    Brugger, R M; Herleth, W H

    1990-01-01

    Several reactors in the United States are potential candidates to deliver beams of intermediate energy neutrons for NCT. At this time, moderators, as compared to filters, appear to be the more effective means of tailoring the flux of these reactors. The objective is to sufficiently reduce the flux of fast neutrons while producing enough intermediate energy neutrons for treatments. At the University of Missouri Research Reactor (MURR), the code MCNP has recently been used to calculate doses in a phantom. First, "ideal" beams of 1, 35, and 1000 eV neutrons were analyzed to determine doses and advantage depths in the phantom. Second, a high quality beam that had been designed to fit in the thermal column of the MURR, was reanalyzed. MCNP calculations of the dose in phantom in this beam confirmed previous calculations and showed that this beam would be a nearly ideal one with neutrons of the desired energy and also a high neutron current. However, installation of this beam will require a significant modification of the thermal column of the MURR. Therefore, a second beam that is less difficult to build and install, but of lower neutron current, has been designed to fit in MURR port F. This beam is designed using inexpensive A1, S, and Pb. The doses calculated in the phantom placed in this beam show that it will be satisfactory for sample tests, animal tests, and possible initial patient trials. Producing this beam will require only modest modifications of the existing tube.

  4. Excitation of the M intermediates of bacteriorhodopsin.

    PubMed

    Tóth-Boconádi, Rudolf; Dér, András; Fábián, László; Taneva, Stefka Germanova; Keszthelyi, Lajos

    2009-01-01

    Protein electric response signals (PERS) of the M intermediates of wild-type bacteriorhodopsin (bR) were recorded. Contrary to earlier findings reporting on a single-phase response upon excitation of the M intermediates, a kinetic analysis of the signals revealed the existence of three components, the fastest and the slowest ones of negative, while the middle one of positive sign with respect to the normal direction of proton pumping. Based on proton motion indicator experiments and molecular dipole calculations, the components were assigned to proton transfer steps and conformational changes driving the bR molecule back from the M to the ground state upon blue light excitation. The fastest, negative pump component was assigned to the proton transfer from D85 to the Schiff base. The subsequent positive component was attributed to rearrangements in the protein core (in the vicinity of the retinal molecule), triggered by the primary proton transfer process. The slowest component was established to reflect charge rearrangements associated with proton uptake by the protein from the bulk.

  5. Spanish Books for Elementary, Intermediate and Advanced Studies: Elementary Schools, High Schools, Colleges, Libraries. Supplement.

    ERIC Educational Resources Information Center

    1968

    This bibliography, a supplement to the 1967 catalog of 2,400 items of Spanish culture and language, includes 4,165 listings and additional categories in: (1) Spanish and Latin American authors, (2) Spanish translations of international authors, (3) fiction-library selections, (4) anthologies-complete works, (5) individual author collections, (6)…

  6. Spanish Books for Elementary, Intermediate and Advanced Studies: Elementary Schools, High Schools, Colleges, Libraries. Supplement.

    ERIC Educational Resources Information Center

    1968

    This bibliography, a supplement to the 1967 catalog of 2,400 items of Spanish culture and language, includes 4,165 listings and additional categories in: (1) Spanish and Latin American authors, (2) Spanish translations of international authors, (3) fiction-library selections, (4) anthologies-complete works, (5) individual author collections, (6)…

  7. INTERMEDIATE CHINESE. YALE LINGUISTIC SERIES, 7.

    ERIC Educational Resources Information Center

    DE FRANCIS, JOHN; TENG, CHIA-YEE

    THIS TEXT IS THE SECOND IN A SERIES OF THREE CLOSELY INTEGRATED VOLUMES FOR TEACHING SPOKEN CHINESE TO SPEAKERS OF ENGLISH AT THE HIGH SCHOOL OR COLLEGE LEVEL. THE TWENTY DIALOGS WHICH FORM THE CORE MATERIAL OF THIS BOOK WERE FIRST RECORDED AND THEN TRANSCRIBED AND EDITED IN PINYIN ROMANIZATION. THUS, THESE CONVERSATIONS ABOUT EVERYDAY TOPICS ARE…

  8. Extra Stimulation in Intermediate Grade Reading.

    ERIC Educational Resources Information Center

    Mason, George E.

    Three types of extra stimulation in reading are discussed: extra teacher time devoted to teaching reading, extra student time devoted to practice in reading, and extra motivation and reinforcement leading to greater amounts of student reading outside the school. Problems are created (1) when teaching time spent on reading is increased in the…

  9. The formation and evolution of intermediate mass black holes

    NASA Astrophysics Data System (ADS)

    Portegies Zwart, S.

    2003-12-01

    Dense star clusters may experience an early phase of core collapse driven by the most massive stars. A runaway collision process starts when the gravothermal collapse of the cluster core happens before the most massive stars explode in supernovae. During the collapse phase one single star experiences multiple (10-100) collisions, preferentially with other massive (30-50 solar mass) main-sequence stars, which also happen to have segregated to the cluster center. Star clusters with initial half-mass relaxation times <50Myr and sufficiently deep central potentials are dominated by this process. (Though alien, there are several clusters which fulfill this criterion in the Milky-way Galaxy.) The phase of runaway growth in these clusters lasts until mass loss by stellar evolution arrests core collapse. The massive object can grow to a mass of about 0.1 per cent of the mass of the entire star cluster. This massive star ultimately collapses to a black hole of intermediate mass. This work is supported by the Royal Dutch Academy of Sciences (KNAW), the Dutch Organization for Scientific Research (NWO), the Netherlands Research School for Astronomy (NOVA) and NASA ATP.

  10. Use of CAS in Secondary School: A Factor Influencing the Transition to University-Level Mathematics?

    ERIC Educational Resources Information Center

    Varsavsky, Cristina

    2012-01-01

    Australian secondary school systems offer three levels of senior (year 12) mathematics studies, none of them compulsory: elementary, intermediate and advanced. The intermediate and advanced studies prepare students for further mathematics studies at university level. In the state of Victoria, there are two versions of intermediate mathematics: one…

  11. Intermediate Pashto Textbook Revised Edition and Intermediate Pashto Workbook Revised Edition.

    ERIC Educational Resources Information Center

    Tegey, Habibullah; Robson, Barbara

    Intermediate Pashto is part of a set of materials for teaching oral and written Afghan Pashto. The transcription of a word or phrase is given only when the word or phrase is introduced, or when pronunciation is the focus. Dialogues and readings on various topics (e.g. food, shopping, weather, family, etc.) are used, with accompanying presentations…

  12. The physical chemistry of Criegee intermediates in the gas phase

    DOE PAGES

    Osborn, David L.; Taatjes, Craig A.

    2015-07-24

    Here, carbonyl oxides, also known as Criegee intermediates, are key intermediates in both gas phase ozonolysis of unsaturated hydrocarbons in the troposphere and solution phase organic synthesis via ozonolysis. Although the study of Criegee intermediates in both arenas has a long history, direct studies in the gas phase have only recently become possible through new methods of generating stabilised Criegee intermediates in sufficient quantities. This advance has catalysed a large number of new experimental and theoretical investigations of Criegee intermediate chemistry. In this article we review the physical chemistry of Criegee intermediates, focusing on their molecular structure, spectroscopy, unimolecular andmore » bimolecular reactions. These recent results have overturned conclusions from some previous studies, while confirming others, and have clarified areas of investigation that will be critical targets for future studies. In addition to expanding our fundamental understanding of Criegee intermediates, the rapidly expanding knowledge base will support increasingly predictive models of their impacts on society.« less

  13. The physical chemistry of Criegee intermediates in the gas phase

    SciTech Connect

    Osborn, David L.; Taatjes, Craig A.

    2015-07-24

    Here, carbonyl oxides, also known as Criegee intermediates, are key intermediates in both gas phase ozonolysis of unsaturated hydrocarbons in the troposphere and solution phase organic synthesis via ozonolysis. Although the study of Criegee intermediates in both arenas has a long history, direct studies in the gas phase have only recently become possible through new methods of generating stabilised Criegee intermediates in sufficient quantities. This advance has catalysed a large number of new experimental and theoretical investigations of Criegee intermediate chemistry. In this article we review the physical chemistry of Criegee intermediates, focusing on their molecular structure, spectroscopy, unimolecular and bimolecular reactions. These recent results have overturned conclusions from some previous studies, while confirming others, and have clarified areas of investigation that will be critical targets for future studies. In addition to expanding our fundamental understanding of Criegee intermediates, the rapidly expanding knowledge base will support increasingly predictive models of their impacts on society.

  14. Energy-Efficient Schools: Three Case Studies from Oregon.

    ERIC Educational Resources Information Center

    2003

    This document presents case studies of three schools or districts in Oregon that have implemented steps to promote energy efficiency. Steps taken by the schools include daylighting, energy audits, special energy loans, new ventilation design, and sustainable building practices. The facilities described are Ash Creek Intermediate School in…

  15. ICI and Penspen in Nigerian and Qatari methanol deals

    SciTech Connect

    Alperowicz, N.

    1992-03-11

    The U.K. consulting and engineering company Penspen Ltd. (London) has signed a second joint venture agreement in Qatar and has selected the ICI (London) methanol process. The technology will also be used in a world-scale methanol plant in Nigeria that Penspen is helping to set up. Under the first agreement, signed on January 1 with Qatar General Petroleum Corp. (QGPC), a 50/50 venture is being formed to build a $370-million, 2,000-m.t./day methanol plant at Umm Said. ICI will provide its low-pressure technology and help market 75% of the output. Completion is due late 1994.

  16. Intermediate range order in alkaline borate glasses

    NASA Astrophysics Data System (ADS)

    Crupi, C.; Carini, G.; Ruello, G.; D'Angelo, G.

    2016-03-01

    We describe the neutron diffraction patterns of a series of alkaline borate glasses at different metal oxide content. Strong differences are observed in the intermediate range order as a function of the specific alkaline ion and of its concentration. On these results, we propose that the first sharp diffraction peak arises from correlations of atoms of voids and show that the compositional variation of this peak intensity in alkaline borate glasses is due to changes in the distribution of void sizes within the three-dimensional network. We argue that our interpretation in terms of interstitial (empty and/or filled) voids, having different sizes, provides a general explanation for all anomalous behaviours revealed for the first sharp diffraction peak.

  17. Intermediate inflation driven by DBI scalar field

    NASA Astrophysics Data System (ADS)

    Nazavari, N.; Mohammadi, A.; Ossoulian, Z.; Saaidi, Kh.

    2016-06-01

    Picking out a DBI scalar field as inflation, the slow-rolling inflationary scenario is studied by attributing an exponential time function to scale factor, known as intermediate inflation. The perturbation parameters of the model are estimated numerically for two different cases, and the final result is compared with Planck data. The diagram of tensor-to-scalar ratio r versus scalar spectra index ns is illustrated, and it is found that they are within an acceptable range as suggested by Planck. In addition, the acquired values for amplitude of scalar perturbation reveal the ability of the model to depict a good picture of the Universe in one of its earliest stages. As a further argument, the non-Gaussianity is investigated, displaying that the model prediction stands in a 68% C.L. regime according to the latest Planck data.

  18. A traditional intermediate moisture meat: Beef cecina.

    PubMed

    Reyes-Cano, R; Dorantes-Alvarez, L; Hernandez-Sanchez, H; Gutierrez-Lopez, G F

    1994-01-01

    Cecina is an intermediate moisture meat produced and consumed to a large extent in Mexico. Four samples of cecina coming from different States of this country, were tested for water activity, colour, texture, fat, protein, moisture and chloride content. Sensory and microbiological analyses were also performed. Different fabrication methods for producing cecina were identified, involving large variations in the formulation of the product. There was a significant difference (P < 0·05) among samples regarding fat and chloride content, colour and texture. Differences in colour and saltiness were recorded through sensory analysis. Microbiological analysis showed higher counts than those recommended in the Mexican Official Standard for chopped and raw meat, due to poor sanitary conditions during production and marketing. Copyright © 1994. Published by Elsevier Ltd.

  19. [The intermediate syndrome during organophosphorus pesticide poisoning].

    PubMed

    Benslama, A; Moutaouakkil, S; Charra, B; Menebhi, L

    2004-04-01

    Acute intoxication by organophosphate pesticides is frequent in Morocco. We report two cases of malathion poisoning complicated by intermediate syndrome. The purpose of this work is to describe distinctive features of this syndrome, it arises 48-96 h after the cholinergic crisis and it is characterized by respiratory paresis with difficulties of weaning from the assisted respiratory, deficit of proximal limbs, neck flexors, and cranial nerves. This syndrome coincides with the prolonged inhibition of the acetylcholinesterase, and is not due to the necrosis of muscular fiber's necrosis. Both clinical and electromyographic features are explained by a combined pre- and postsynaptic dysfunction of the neuromuscular transmission. The difficulty of this syndrome lies in its rarity and also its severity, because of the respiratory failure, which justifies medical supervision in intensive care unit, for at least 96 h, in expectation for the respiratory distress, all the more cholinergic syndrome is intense.

  20. The intermediate comets and nongravitational effects

    NASA Technical Reports Server (NTRS)

    Yeomans, D. K.

    1986-01-01

    The motions of the intermediate-period comets Pons-Brooks, Olbers, Brorsen-Metcalf, and Westphal are investigated over their observed intervals. The three apparitions of comets Pons-Brooks and Olbers were successfully linked, using the now standard nongravitational-force model. The two apparitions of Comet Brorsen-Metcalf were successfully linked without the need for nongravitational effects. For the 1852 and 1913 apparitions of Comet Westphal, complete success was not achieved in modeling the comet's motion either with or without nongravitational effects. However, by including these effects, the comet's astrometric observations could be represented significantly better than if they were assumed inoperative. Comet Westphal's dynamic and photometric behavior suggests its complete disintegration before reaching perihelion in 1913. If the very large radial nongravitational parameter determined for Comet Westphal is due to the comet's disintegration into dust, then the resultant dust-particle size is of the order of 0.8 mm.

  1. Intermediate filaments in. cap alpha. -keratins

    SciTech Connect

    Fraser, R.D.B.; MacRae, T.P.; Parry, D.A.D.; Suzuki, E.

    1986-03-01

    Previous x-ray diffraction studies on the ..cap alpha..-keratins of hair and wool have revealed that the intermediate filaments (IF) have a helical structure rendered imperfect by a precisely defined dislocation. It has also been possible to deduce a surface lattice for the IF and to determine the number of IF molecules associated with each lattice point. In this work this information is combined with data on the ionic interactions between the coiled-coil rope segments of the IF molecules to provide a plausible model for the pattern of interactions that stabilize the framework of the IF in the hard ..cap alpha..-keratins. Similar interaction studies of the proteins from the IF in the so-called soft ..cap alpha..-keratin from the stratum corneum layer of the skin suggest that they are likely to have an essentially similar pattern.

  2. A Mechanochemical Switch to Control Radical Intermediates

    PubMed Central

    2015-01-01

    B12-dependent enzymes employ radical species with exceptional prowess to catalyze some of the most chemically challenging, thermodynamically unfavorable reactions. However, dealing with highly reactive intermediates is an extremely demanding task, requiring sophisticated control strategies to prevent unwanted side reactions. Using hybrid quantum mechanical/molecular mechanical simulations, we follow the full catalytic cycle of an AdoB12-dependent enzyme and present the details of a mechanism that utilizes a highly effective mechanochemical switch. When the switch is “off”, the 5′-deoxyadenosyl radical moiety is stabilized by releasing the internal strain of an enzyme-imposed conformation. Turning the switch “on,” the enzyme environment becomes the driving force to impose a distinct conformation of the 5′-deoxyadenosyl radical to avoid deleterious radical transfer. This mechanochemical switch illustrates the elaborate way in which enzymes attain selectivity of extremely chemically challenging reactions. PMID:24846280

  3. A mechanochemical switch to control radical intermediates.

    PubMed

    Brunk, Elizabeth; Kellett, Whitney F; Richards, Nigel G J; Rothlisberger, Ursula

    2014-06-17

    B₁₂-dependent enzymes employ radical species with exceptional prowess to catalyze some of the most chemically challenging, thermodynamically unfavorable reactions. However, dealing with highly reactive intermediates is an extremely demanding task, requiring sophisticated control strategies to prevent unwanted side reactions. Using hybrid quantum mechanical/molecular mechanical simulations, we follow the full catalytic cycle of an AdoB₁₂-dependent enzyme and present the details of a mechanism that utilizes a highly effective mechanochemical switch. When the switch is "off", the 5'-deoxyadenosyl radical moiety is stabilized by releasing the internal strain of an enzyme-imposed conformation. Turning the switch "on," the enzyme environment becomes the driving force to impose a distinct conformation of the 5'-deoxyadenosyl radical to avoid deleterious radical transfer. This mechanochemical switch illustrates the elaborate way in which enzymes attain selectivity of extremely chemically challenging reactions.

  4. The intermediate comets and nongravitational effects

    NASA Technical Reports Server (NTRS)

    Yeomans, D. K.

    1986-01-01

    The motions of the intermediate-period comets Pons-Brooks, Olbers, Brorsen-Metcalf, and Westphal are investigated over their observed intervals. The three apparitions of comets Pons-Brooks and Olbers were successfully linked, using the now standard nongravitational-force model. The two apparitions of Comet Brorsen-Metcalf were successfully linked without the need for nongravitational effects. For the 1852 and 1913 apparitions of Comet Westphal, complete success was not achieved in modeling the comet's motion either with or without nongravitational effects. However, by including these effects, the comet's astrometric observations could be represented significantly better than if they were assumed inoperative. Comet Westphal's dynamic and photometric behavior suggests its complete disintegration before reaching perihelion in 1913. If the very large radial nongravitational parameter determined for Comet Westphal is due to the comet's disintegration into dust, then the resultant dust-particle size is of the order of 0.8 mm.

  5. Kinetic advantage of controlled intermediate nuclear fusion

    SciTech Connect

    Guo Xiaoming

    2012-09-26

    The dominated process of controlled fusion is to let nuclei gain enough kinetic energy to overcome Coulomb barrier. As a result, a fusion scheme can consider two factors in its design: to increase kinetic energy of nuclei and to alter the Coulomb barrier. Cold Fusion and Hot fusion are all one-factor schemes while Intermediate Fusion is a twofactors scheme. This made CINF kinetically superior. Cold Fusion reduces deuteron-deuteron distance, addressing Coulomb barrier, and Hot Fusion heat up plasma into extreme high temperature, addressing kinetic energy. Without enough kinetic energy made Cold Fusion skeptical. Extreme high temperature made Hot Fusion very difficult to engineer. Because CIFN addresses both factors, CIFN is a more promising technique to be industrialized.

  6. Kinetic advantage of controlled intermediate nuclear fusion

    NASA Astrophysics Data System (ADS)

    Guo, Xiaoming

    2012-09-01

    The dominated process of controlled fusion is to let nuclei gain enough kinetic energy to overcome Coulomb barrier. As a result, a fusion scheme can consider two factors in its design: to increase kinetic energy of nuclei and to alter the Coulomb barrier. Cold Fusion and Hot fusion are all one-factor schemes while Intermediate Fusion is a twofactors scheme. This made CINF kinetically superior. Cold Fusion reduces deuteron-deuteron distance, addressing Coulomb barrier, and Hot Fusion heat up plasma into extreme high temperature, addressing kinetic energy. Without enough kinetic energy made Cold Fusion skeptical. Extreme high temperature made Hot Fusion very difficult to engineer. Because CIFN addresses both factors, CIFN is a more promising technique to be industrialized.

  7. Pineal parenchymal tumor of intermediate differentiation.

    PubMed

    Patil, Meena; Karandikar, Manjiri

    2015-01-01

    The 2007 World Health Organization classification of tumors of the central nervous system identified "pineal parenchymal tumor of intermediate differentiation" (PPTID) as a new pineal parenchymal neoplasm, located between pineocytoma and pineoblastoma as grade II or III. Because of the small number of reported cases, the classification of PPT is still a matter of controversy. We report a case of PPTID. A 25-year-old female patient was admitted to hospital with complaints of a headache, nausea, vomiting since 1-year. Computed tomography/magnetic resonance imaging of the brain showed well-defined, mildly enhancing lesion in the region of the pineal gland with areas of calcification. The tumor was excised. After 3 years, she presented with metastasis in thoracic and lumbosacral spinal region. This is a rare event.

  8. The intermediate distance hypothesis of biological invasions.

    PubMed

    Seebens, Hanno; Essl, Franz; Blasius, Bernd

    2017-02-01

    Biological invasions are a worldwide phenomenon, but the global flows between native and alien regions have rarely been investigated in a cross-taxonomic study. We therefore lack a thorough understanding of the global patterns of alien species spread. Using native and alien ranges of 1380 alien species, we show that the number of alien species follows a hump-shaped function of geographic distance. We observe distinct variations in the relationship between alien species exchanges and distance among taxonomic groups, which relate to the taxa-specific dispersal modes and their pathways of introduction. We formulate a simple statistical model, combining trade volume and biogeographic dissimilarity, which reproduces the observed pattern in good agreement with reported data and even captures variations among taxonomic groups. This study demonstrates the universality of the intermediate distance hypothesis of alien species spread across taxonomic groups, which will help to improve the predictability of new alien species arrivals.

  9. NN and Nd Scattering with Intermediate Dibaryons

    NASA Astrophysics Data System (ADS)

    Platonova, Maria N.

    2017-03-01

    Excitation of intermediate dibaryon resonances in hadronic processes accompanied by high momentum transfers is considered. It is shown that some basic features of NN inelastic scattering with single- or double-pion production can be effectively described by taking into account the short-range s-channel dibaryon excitation along with peripheral t-channel meson-exchange processes. In particular, isovector dibaryons with I(J^P)=1(2^+), 1(3^-) and 1(2^-) are shown to play an important role in reproducing the cross sections and especially polarization observables in the basic single-pion production reaction pp → dπ ^+, while an isoscalar I(J^P)=0(3^+) dibaryon is crucial for describing the basic double-pion production process pn → d (π π )_0. Possible generalization of resonance (dibaryon) mechanisms considered in NN scattering to Nd elastic and inelastic scattering is also discussed.

  10. Slab tears and intermediate-depth seismicity

    USGS Publications Warehouse

    Meighan, Hallie E.; Ten Brink, Uri; Pulliam, Jay

    2013-01-01

    Active tectonic regions where plate boundaries transition from subduction to strike slip can take several forms, such as triple junctions, acute, and obtuse corners. Well-documented slab tears that are associated with high rates of intermediate-depth seismicity are considered here: Gibraltar arc, the southern and northern ends of the Lesser Antilles arc, and the northern end of Tonga trench. Seismicity at each of these locations occurs, at times, in the form of swarms or clusters, and various authors have proposed that each marks an active locus of tear propagation. The swarms and clusters start at the top of the slab below the asthenospheric wedge and extend 30–60 km vertically downward within the slab. We propose that these swarms and clusters are generated by fluid-related embrittlement of mantle rocks. Focal mechanisms of these swarms generally fit the shear motion that is thought to be associated with the tearing process.

  11. Intermediate photovoltaic system/utility interface experience

    NASA Astrophysics Data System (ADS)

    Biringer, K. L.; McDowell, J. F.; Rogers, C. B.; Haskins, D. E.

    A description is given of 11 intermediate photovoltaic application projects, including the Arizona Public Service Company project, the E-Systems 27 kW photovoltaic concentrator application experiment, a 110 kW photovoltaic application experiment in Orlando, Florida, the Lea County photovoltaic flat plate photovoltaic experiment in southeastern New Mexico, the Mt. Laguna photovoltaic flat plate installation in California, the San Bernardino 35 kW photovoltaic flat plate project in California, and the Solar Power flat plate photovoltaic experiment in Massachusetts. It is pointed out that the most significant point to be made relative to the interface of photovoltaic systems with the utility grid is that it can be done successfully.

  12. EGRET sources at intermediate galactic latitude

    NASA Technical Reports Server (NTRS)

    Halpern, Jules P. (Principal Investigator)

    1996-01-01

    This paper presents the abstracts of four papers (using ROSAT data) that are submitted to refereed journals during the current reporting period. The papers are: (1) Extreme x-ray variability in the narrow-line QSO PHL 1092; (2) The Geminga pulsar (soft x-ray variability and an EUVE observation); (3) a broad-band x-ray study of the geminga pulsar; and (4) Classification of IRAS-selected x-ray galaxies in the ROSAT all-sky survey. The abstracts of these papers are given in the next four sections of this report, and their status is given in the Appendix. Finally, two new projects (De-identifying a non-AGN and EGRET sources at intermediate galactic latitude) for which ROSAT data were recently received are currently being studied under this grant. A summary of work in progress on these new projects is given in the last two sections of this report.

  13. Picornavirus uncoating intermediate captured in atomic detail

    PubMed Central

    Ren, Jingshan; Wang, Xiangxi; Hu, Zhongyu; Gao, Qiang; Sun, Yao; Li, Xuemei; Porta, Claudine; Walter, Thomas S.; Gilbert, Robert J.; Zhao, Yuguang; Axford, Danny; Williams, Mark; McAuley, Katherine; Rowlands, David J.; Yin, Weidong; Wang, Junzhi; Stuart, David I.; Rao, Zihe; Fry, Elizabeth E.

    2013-01-01

    It remains largely mysterious how the genomes of non-enveloped eukaryotic viruses are transferred across a membrane into the host cell. Picornaviruses are simple models for such viruses, and initiate this uncoating process through particle expansion, which reveals channels through which internal capsid proteins and the viral genome presumably exit the particle, although this has not been clearly seen until now. Here we present the atomic structure of an uncoating intermediate for the major human picornavirus pathogen CAV16, which reveals VP1 partly extruded from the capsid, poised to embed in the host membrane. Together with previous low-resolution results, we are able to propose a detailed hypothesis for the ordered egress of the internal proteins, using two distinct sets of channels through the capsid, and suggest a structural link to the condensed RNA within the particle, which may be involved in triggering RNA release. PMID:23728514

  14. Physical properties of cytoplasmic intermediate filaments.

    PubMed

    Block, Johanna; Schroeder, Viktor; Pawelzyk, Paul; Willenbacher, Norbert; Köster, Sarah

    2015-11-01

    Intermediate filaments (IFs) constitute a sophisticated filament system in the cytoplasm of eukaryotes. They form bundles and networks with adapted viscoelastic properties and are strongly interconnected with the other filament types, microfilaments and microtubules. IFs are cell type specific and apart from biochemical functions, they act as mechanical entities to provide stability and resilience to cells and tissues. We review the physical properties of these abundant structural proteins including both in vitro studies and cell experiments. IFs are hierarchical structures and their physical properties seem to a large part be encoded in the very specific architecture of the biopolymers. Thus, we begin our review by presenting the assembly mechanism, followed by the mechanical properties of individual filaments, network and structure formation due to electrostatic interactions, and eventually the mechanics of in vitro and cellular networks. This article is part of a Special Issue entitled: Mechanobiology.

  15. Navigating Intermediate Targets: The Nervous System Midline

    PubMed Central

    Dickson, Barry J.; Zou, Yimin

    2010-01-01

    In a bilaterally symmetric animal, the midline plays a key role in directing axon growth during wiring of the nervous system. Midline cells provide a variety of guidance cues for growing axons, to which different types of axons respond in different ways and at different times. For some axons, the midline is an intermediate target. They first seek it out, but then move on towards their final targets on the opposite side. For others, the midline is a repulsive barrier that keeps them on their own side of the midline. And for many of these axons the midline provides signals that guide them along specific lateral pathways or up and down the longitudinal axis. PMID:20534708

  16. Intermediate load modules for test and evaluation

    NASA Technical Reports Server (NTRS)

    1984-01-01

    Photovoltaic modules were tested for qualification. Tests involved the following: (1) delivery of 20 solar cells for use as reference cells; (2) module documentation and inspection plans specifying the 10 Group I modules; (3) design review of module documentation from Group I modules; (4) revise module documentation to overcome any problems of deficiencies associated with the Group I modules; (5) delivery of 10 Group II modules built to revised specifications; (6) testing of Group II modules to the criteria as outlined in qualification specification. It is found that the solarvolt MSP43E40B satisfies the design criteria of qualification specification for intermediate load modules. Design changes were made in the Group I modules to overcome the deficiencies which allowed Group II modules to pass the qualification tests.

  17. Supervising Remote Humanoids Across Intermediate Time Delay

    NASA Technical Reports Server (NTRS)

    Hambuchen, Kimberly; Bluethmann, William; Goza, Michael; Ambrose, Robert; Rabe, Kenneth; Allan, Mark

    2006-01-01

    The President's Vision for Space Exploration, laid out in 2004, relies heavily upon robotic exploration of the lunar surface in early phases of the program. Prior to the arrival of astronauts on the lunar surface, these robots will be required to be controlled across space and time, posing a considerable challenge for traditional telepresence techniques. Because time delays will be measured in seconds, not minutes as is the case for Mars Exploration, uploading the plan for a day seems excessive. An approach for controlling humanoids under intermediate time delay is presented. This approach uses software running within a ground control cockpit to predict an immersed robot supervisor's motions which the remote humanoid autonomously executes. Initial results are presented.

  18. "Intermediate" population control and comprehensive community development.

    PubMed

    Tian, X

    1993-01-01

    China's fertility rapidly declined since the 1970s. Family planning efforts and rigorous population control were recognized as having a significant influence on the 50% decline in fertility to 2.25 in 1990. Little attention was given to intermediate level research on the determinants of fertility decline. The intermediate level is the community, which is a suitable level for analysis of Chinese fertility because income is relatively homogenous at the community level. Communities have common economic interests, and multiple births by one member encroaches on the resources of other members. Community social organization links the micro with the macro birth control of national government. Cultural values shape reproductive patterns in communities. A determinant of population control is the general level of development in the community. Several models of development are apparent: the traditional agricultural topology, the modern industrial structure topology, and the transitional industrial structure topology. Communities may vary in size from small, to medium, to large. Family planning core households can be effective in educating adjacent households and responding flexibly. The medium community has close spatial connections between population management and local economy and culture. A large community corresponds to a township in rural areas and neighborhood in urban areas. Historical period influences reflect the level and structure of social economic development. In the Hainan community with population of 6.5 million, there are still backward economic conditions and a high birth rate. An experimental zone development group was established in 1991 to enhance population and economic development in five agricultural communities. Within 2 years, progress had been made in market reform and communities were modeled on "little government and big societies." The experimental program expanded knowledge about population issues, promoted education and training, and secured

  19. Intermediate Ethanol Blends Catalyst Durability Program

    SciTech Connect

    West, Brian H; Sluder, Scott; Knoll, Keith; Orban, John; Feng, Jingyu

    2012-02-01

    In the summer of 2007, the U.S. Department of Energy (DOE) initiated a test program to evaluate the potential impacts of intermediate ethanol blends (also known as mid-level blends) on legacy vehicles and other engines. The purpose of the test program was to develop information important to assessing the viability of using intermediate blends as a contributor to meeting national goals for the use of renewable fuels. Through a wide range of experimental activities, DOE is evaluating the effects of E15 and E20 - gasoline blended with 15% and 20% ethanol - on tailpipe and evaporative emissions, catalyst and engine durability, vehicle driveability, engine operability, and vehicle and engine materials. This report provides the results of the catalyst durability study, a substantial part of the overall test program. Results from additional projects will be reported separately. The principal purpose of the catalyst durability study was to investigate the effects of adding up to 20% ethanol to gasoline on the durability of catalysts and other aspects of the emissions control systems of vehicles. Section 1 provides further information about the purpose and context of the study. Section 2 describes the experimental approach for the test program, including vehicle selection, aging and emissions test cycle, fuel selection, and data handling and analysis. Section 3 summarizes the effects of the ethanol blends on emissions and fuel economy of the test vehicles. Section 4 summarizes notable unscheduled maintenance and testing issues experienced during the program. The appendixes provide additional detail about the statistical models used in the analysis, detailed statistical analyses, and detailed vehicle specifications.

  20. Covalent functionalization of graphene with reactive intermediates.

    PubMed

    Park, Jaehyeung; Yan, Mingdi

    2013-01-15

    Graphene, a material made exclusively of sp(2) carbon atoms with its π electrons delocalized over the entire 2D network, is somewhat chemically inert. Covalent functionalization can enhance graphene's properties including opening its band gap, tuning conductivity, and improving solubility and stability. Covalent functionalization of pristine graphene typically requires reactive species that can form covalent adducts with the sp(2) carbon structures in graphene. In this Account, we describe graphene functionalization reactions using reactive intermediates of radicals, nitrenes, carbenes, and arynes. These reactive species covalently modify graphene through free radical addition, CH insertion, or cycloaddition reactions. Free radical additions are among the most common reaction, and these radicals can be generated from diazonium salts and benzoyl peroxide. Electron transfer from graphene to aryl diazonium ion or photoactivation of benzoyl peroxide yields aryl radicals that subsequently add to graphene to form covalent adducts. Nitrenes, electron-deficient species generated by thermal or photochemical activation of organic azides, can functionalize graphene very efficiently. Because perfluorophenyl nitrenes show enhanced bimolecular reactions compared with alkyl or phenyl nitrenes, perfluorophenyl azides are especially effective. Carbenes are used less frequently than nitrenes, but they undergo CH insertion and C═C cycloaddition reactions with graphene. In addition, arynes can serve as a dienophile in a Diels-Alder type reaction with graphene. Further study is needed to understand and exploit the chemistry of graphene. The generation of highly reactive intermediates in these reactions leads to side products that complicate the product composition and analysis. Fundamental questions remain about the reactivity and regioselectivity of graphene. The differences in the basal plane and the undercoordinated edges of graphene and the zigzag versus arm-chair configurations

  1. Research Results and Final Report for the Dispute Management in the Schools Project. PCR Working Paper Series.

    ERIC Educational Resources Information Center

    Araki, Charles T.; And Others

    To develop and test an experimental model of dispute or conflict management through mediation in a school complex, and to examine the basic nature of conflict in schools, the Dispute Management in the Schools Project (DMSP) was conducted. The 3-year mediation project, begun in January 1986, involved an elementary school, an intermediate school, a…

  2. SUPPLEMENTING THE PROGRAMS AND SERVICES OF RURAL SCHOOL SYSTEMS BY NEW TYPE REGIONAL SERVICE AGENCIES.

    ERIC Educational Resources Information Center

    LOVELESS, JOHN E.

    THE INTERMEDIATE DISTRICT, ESTABLISHED BY LAW IN NEW YORK STATE IN 1948, IS A COOPERATIVE EDUCATIONAL VENTURE PROVIDING SMALL RURAL SCHOOLS WITH SERVICES WHICH ARE NOT USUALLY POSSIBLE, DUE TO THE SIZE AND ISOLATION OF THESE SCHOOL DISTRICTS. SEVERAL OF THESE INTERMEDIATE DISTRICTS, LABELED BOCES (BOARD OF COOPERATIVE EDUCATIONAL SERVICES), HAVE…

  3. Empowerment or Impediment? School Governance in the School-Based Management Era in Hong Kong

    ERIC Educational Resources Information Center

    Kwan, Paula; Li, Benjamin Yuet-man

    2015-01-01

    Following the international trend in education towards democracy and decentralization, the Hong Kong government introduced a school-based management (SBM) system about two decades ago. It is widely recognized in the literature that decentralization, empowering school level management and marginalizing the influence of the intermediate level of…

  4. Empowerment or Impediment? School Governance in the School-Based Management Era in Hong Kong

    ERIC Educational Resources Information Center

    Kwan, Paula; Li, Benjamin Yuet-man

    2015-01-01

    Following the international trend in education towards democracy and decentralization, the Hong Kong government introduced a school-based management (SBM) system about two decades ago. It is widely recognized in the literature that decentralization, empowering school level management and marginalizing the influence of the intermediate level of…

  5. Intergalactic stellar populations in intermediate redshift clusters

    NASA Astrophysics Data System (ADS)

    Melnick, J.; Giraud, E.; Toledo, I.; Selman, F.; Quintana, H.

    2012-11-01

    A substantial fraction of the total stellar mass in rich clusters of galaxies resides in a diffuse intergalactic component usually referred to as the intracluster light (ICL). Theoretical models indicate that these intergalactic stars originate mostly from the tidal interaction of the cluster galaxies during the assembly history of the cluster, and that a significant fraction of these stars could have formed in situ from the late infall of cold metal-poor gas clouds on to the cluster. However, these models also overpredict the fraction of stellar mass in the ICL by a substantial margin, something that is still not well understood. The models also make predictions about the age distribution of the ICL stars, which may provide additional observational constraints. Here we present population synthesis models for the ICL of an intermediate redshift (z = 0.29) X-ray cluster that we have extensively studied in previous papers. The advantage of observing intermediate redshift clusters rather than nearby ones is that the former fit the field of view of multi-object spectrographs in 8-m telescopes and therefore permit us to encompass most of the ICL with only a few well-placed slits. In this paper we show that by stacking spectra at different locations within the ICL it is possible to reach sufficiently high signal-to-noise ratios to fit population synthesis models and derive meaningful results. The models provide ages and metallicities for the dominant populations at several different locations within the ICL and the brightest cluster galaxies (BCG) halo, as well as measures of the kinematics of the stars as a function of distance from the BCG. We thus find that the ICL in our cluster is dominated by old metal-rich stars, at odds with what has been found in nearby clusters where the stars that dominate the ICL are old and metal poor. While we see weak evidence of a young, metal-poor component, if real, these young stars would amount to less than 1 per cent of the total ICL

  6. DNA packaging intermediates of bacteriophage Φ174

    PubMed Central

    Music, Cynthia L; Cheng, R Holland; Bowen, Zorina; McKenna, Robert; Rossmann, Michael G; Baker, Timothy S; Incardona, Nino L

    2014-01-01

    Background Like many viruses, bacteriophage ΦX174 packages its I)NA genome into a procapsid that is assembled from structural intermediates and scaffolding proteins. The procapsid contains the structural proteins F, G and H, as well as the scaffolding proteins B and D. Provirions are formed by packaging of DNA together with the small internal J proteins, while losing at least some of the B scaffolding proteins. Eventually, loss of the I) scaffolding proteins and the remaining B proteins leads to the formation of mature virions. Results ΦX174 108S 'procapsids' have been purified in milligram quantities by removing 114S (mature virion) and 70S (abortive capsid) particles from crude lysates by differential precipitation with polyethylene glycol. 132S 'provirions' were purified on sucrose gradients in the presence of EDTA. Cryo-electron microscopy (cryo-EM) was used to obtain reconstructions of procapsids and provirions. Although these are very similar to each other, their structures differ greatly from that of the virion. The F and G proteins, whose atomic structures in virions were previously determined from X-ray crystallography, were fitted into the cryo-EM reconstructions. This showed that the pentamer of G proteins on each five-fold vertex changes its conformation only slightly during DNA packaging and maturation, whereas major tertiary and quaternary structural changes occur in the F protein. The procapsids and provirions were found to contain 120 copies of the I) protein arranged as tetramers on the twofold axes. IDNA might enter procapsids through one of the 30 Å diameter holes on the icosahedral three-fold axes. Conclusions Combining cryo-EM image reconstruction and X-ray crystallography has revealed the major conformational changes that can occur in viral assembly. The function of the scaffolding proteins may be, in part, to support weak interactions between the structural proteins in the procapsids and to cover surfaces that are subsequently required for

  7. Energetics of intermediates in membrane fusion: comparison of stalk and inverted micellar intermediate mechanisms.

    PubMed Central

    Siegel, D P

    1993-01-01

    To understand the mechanism of membrane fusion, we have to infer the sequence of structural transformations that occurs during the process. Here, it is shown how one can estimate the lipid composition-dependent free energies of intermediate structures of different geometries. One can then infer which fusion mechanism is the best explanation of observed behavior in different systems by selecting the mechanism that requires the least energy. The treatment involves no adjustable parameters. It includes contributions to the intermediate energy resulting from the presence of hydrophobic interstices within structures formed between apposed bilayers. Results of these calculations show that a modified form of the stalk mechanism proposed by others is a likely fusion mechanism in a wide range of lipid compositions, but a mechanism based on inverted micellar intermediates (IMIs) is not. This should be true even in the vicinity of the lamellar/inverted hexagonal phase transition, where IMI formation would be most facile. Another prediction of the calculations is that traces of apolar lipids (e.g., long-chain alkanes) in membranes should have a substantial influence on fusion rates in general. The same theoretical methods can be used to generate and refine mechanisms for protein-mediated fusion. PMID:8298039

  8. A Search for the Elusive Setting Events of School Vandalism: A Correlational Study.

    ERIC Educational Resources Information Center

    Mayer, G. Roy; And Others

    1987-01-01

    The study examined 28 intermediate schools to identify factors in the school environment related to vandalism. Vandalism cost and frequency were found to be greater in schools that had lower scores on a school discipline survey. Results are discussed in terms of setting factors, punishment, and reinforcement. (Author)

  9. Structure and evolution of time-dependent intermediate shocks

    NASA Technical Reports Server (NTRS)

    Wu, C. C.; Kennel, C. F.

    1992-01-01

    A quantitative description of time-dependent intermediate shocks is formulated using the Cohen-Kulsrud-Burgers equations. In noncoplanar Riemann problems, time-dependent two-three transition intermediate shocks evolve in time as a localized self-similar structure whose strength decreases as 1/the square root of t, and whose width expands as the square root of t. Time-dependent intermediate shocks offer a way of solving the noncoplanar MHD Riemann problem.

  10. Restitution: Another Two-Way Street in School Cases?

    ERIC Educational Resources Information Center

    Zirkel, Perry A.

    2003-01-01

    Analyzes complex Minnesota case wherein the state intermediate, appellate court upheld (2-1) juvenile court's order that a high school student expelled for making a bomb threat pay the district's tutoring costs and attorney's fees. (PKP)

  11. Restitution: Another Two-Way Street in School Cases?

    ERIC Educational Resources Information Center

    Zirkel, Perry A.

    2003-01-01

    Analyzes complex Minnesota case wherein the state intermediate, appellate court upheld (2-1) juvenile court's order that a high school student expelled for making a bomb threat pay the district's tutoring costs and attorney's fees. (PKP)

  12. School/Community Involvement at the Secondary Level

    ERIC Educational Resources Information Center

    Haugen, Percy; And Others

    1977-01-01

    Discusses the development of communication between school and community. This includes several vital procedures and contributing organizational structures which provide secondary and intermediate age students with exposures to a variety of career opportunities. (Author/RK)

  13. Molecular phylogeny of metazoan intermediate filament proteins.

    PubMed

    Erber, A; Riemer, D; Bovenschulte, M; Weber, K

    1998-12-01

    We have cloned cytoplasmic intermediate filament (IF) proteins from a large number of invertebrate phyla using cDNA probes, the monoclonal antibody IFA, peptide sequence information, and various RT-PCR procedures. Novel IF protein sequences reported here include the urochordata and nine protostomic phyla, i.e., Annelida, Brachiopoda, Chaetognatha, Echiura, Nematomorpha, Nemertea, Platyhelminthes, Phoronida, and Sipuncula. Taken together with the wealth of data on IF proteins of vertebrates and the results on IF proteins of Cephalochordata, Mollusca, Annelida, and Nematoda, two IF prototypes emerge. The L-type, which includes 35 sequences from 11 protostomic phyla, shares with the nuclear lamins the long version of the coil 1b subdomain and, in most cases, a homology segment of some 120 residues in the carboxyterminal tail domain. The S-type, which includes all four subfamilies (types I to IV) of vertebrate IF proteins, lacks 42 residues in the coil 1b subdomain and the carboxyterminal lamin homology segment. Since IF proteins from all three phyla of the chordates have the 42-residue deletion, this deletion arose in a progenitor prior to the divergence of the chordates into the urochordate, cephalochordate, and vertebrate lineages, possibly already at the origin of the deuterostomic branch. Four phyla recently placed into the protostomia on grounds of their 18S rDNA sequences (Brachiopoda, Nemertea, Phoronida, and Platyhelminthes) show IF proteins of the L-type and fit by sequence identity criteria into the lophotrochozoic branch of the protostomia.

  14. Criegee Intermediates React with Levoglucosan on Water.

    PubMed

    Enami, Shinichi; Hoffmann, Michael R; Colussi, A J

    2017-08-17

    Levoglucosan (Levo), a C6-anhydrosaccharide produced in the combustion of cellulosic materials, is the major component of aerosols produced from biomass burning over vast regions worldwide. Levo has long been considered chemically inert and thus has been used as a tracer of biomass burning sources. However, we now show that sugars including Levo, glucose, arabitol, and mannitol react rapidly with Criegee intermediates (CIs) generated during the ozonolysis of sesquiterpenes on the surface of water:acetonitrile microjets. Hydrophilic Levo reacts faster with CIs than with water or surface-active 1-octanol at air-aqueous interfaces. This unexpected phenomenon is likely associated with the relatively low water density at air-aqueous interfaces coupled with a higher gas-phase acidity of the saccharide hydroxyl groups (i.e., -OH) versus n-alkanols. Results presented herein show that aerosol saccharides are in fact reactive toward CIs. Given the abundance of saccharides in the atmosphere, they may be important contributors to the growth and mass loading of secondary organic aerosols.

  15. Intermediate endpoint biomarkers for lung cancer chemoprevention

    NASA Astrophysics Data System (ADS)

    MacAulay, Calum E.; Lam, Stephen; Klein-Parker, Helga; Gazdar, Adi; Guillaud, Martial; Payne, Peter W.; Le Riche, Jean C.; Dawe, Chris; Band, Pierre; Palcic, Branko

    1998-04-01

    Given the demographics of current and ex-smoking populations in North America, lung cancer will be a major problem in the foreseeable future. Early detection and treatment of lung cancer holds great promise for the management of this disease. Unlike cervical cancer, the physical, complete removal/destruction of all dysplastic lesions in the bronchial tree is not possible; however, treatment of the lesions using a chemopreventive agent is. Intermediate biomarkers have been used to screen promising chemopreventive agents for larger population studies. We have examined the natural history of lung cancer development by following a group of subjects at high risk of developing lung cancer using fluorescence endoscopy to identify the areas of abnormality for biopsy. Approximately 900 biopsies have been collected in this fashion and graded by at least two experienced, expert pathologists. Using an interactive version of the Cyto-Savant (Oncometrics Imaging Corp.), cytometric and tissue architectural data were collected from these biopsies. Using only the data from the normal and invasive cancer biopsies, quantitative morphometric and architectural indices were generated and calculated for all the collected biopsies. These indices were compared with Loss of Heterozygosity (LOH) of ten sites commonly associated with cancer. These results and the application of these quantitative measures to two small chemoprevention studies will be reported.

  16. Mechanical properties of intermediate filament proteins

    PubMed Central

    Charrier, Elisabeth E.; Janmey, Paul A.

    2016-01-01

    Purified intermediate filament proteins can be reassembled in vitro to produce polymers closely resembling those found in cells, and these filament form viscoelastic gels. The crosslinks holding IFs together in the network include specific bonds between polypeptides extending from the filament surface and ionic interactions mediated by divalent cations. IF networks exhibit striking non-linear elasticity with stiffness, as quantified by shear modulus, increasing an order of magnitude as the networks are deformed to large stains resembling those that soft tissues undergo in vivo. Individual Ifs can be stretched to more than 2 or 3 times their resting length without breaking. At least ten different rheometric methods have been used to quantify the viscoelasticity of IF networks over a wide range of timescales and strain magnitudes. The mechanical roles of different classes of IF on mesenchymal and epithelial cells in culture have also been studied by an even wider range of microrheological methods. These studies have documented the effects on cell mechanics when IFs are genetically or pharmacologically disrupted or when normal or mutant IF proteins are exogenously expressed in cells. Consistent with in vitro rheology, the mechanical role of IFs is more apparent as cells are subjected to larger and more frequent deformations. PMID:26795466

  17. Abrasion fission reactions at intermediate energies

    NASA Astrophysics Data System (ADS)

    Bowry, Michael

    2016-09-01

    In-flight fission of 0.3-1.0 GeV A uranium beams at GSI Helmholtz Center for Heavy Ion Research and RIKEN Radioactive Isotope Beam Factory have demonstrated that the yield of fission fragments is naturally attuned to the N, Z and excitation energy of the projectile prefragments formed in peripheral nuclear collisions. Similar measurements at intermediate energies (less than 0.1 GeV A) are scarce despite the potential proximity to the threshold of limiting fragmentation proposed by Benecke et al. and may provide a sensitive probe of prefragment formation. Cross section measurements spanning 20 different isotopic chains from nickel to silver are presented following in-flight fission reactions of an 80 MeV A uranium-238 beam on a diamond active target at the National Superconducting Cyclotron Laboratory (NSCL) at Michigan State University (East Lansing, USA). Fission products were identified on an event-by-event basis by correlating time-of-flight and energy-loss measurements in the S800 spectrograph with in-flight gamma-decays reconstructed by the Gamma-Ray Energy Tracking Array (GRETINA) in the rest frame of the projectile. Transmission through the S800 has been determined using state-of-the-art simulations developed in the LISE + + code. et al. A full author list is available on request.

  18. Intermediate Redshift Galaxy Clusters from DPOSS

    NASA Astrophysics Data System (ADS)

    Lopes, P. A. A.

    2003-06-01

    In this thesis we discuss the selection of intermediate redshift galaxy cluster candidates based on the Digitized Second Palomar Observatory Sky Survey (DPOSS). Clusters are detected using the best DPOSS plates based on seeing and limiting magnitude. The search is further restricted to high galactic latitudes (|b| > 50 °), where stellar contamination is mild and nearly uniform. The input galaxy catalogs used for this search are limited to r = 21.1. The cluster selection is based on two techniques, the adaptive kernel and the voronoi tesselation methods. The final combined catalog contains ~ 10,000 candidates over ~ 2,700 square degrees, with ~ 0.30 and ~ 40 (Ngals is a richness estimate we provide). Rich clusters are detected down to z ~ 0.5. This cluster catalog is a supplement to the previous DPOSS catalogs, being the largest resource of rich clusters in this redshift range to date. In order to optimize the detection algorithms and estimate the contamination and completeness rates, we perform a large number of simulations for both catalogs. Redshift and richness estimates are also provided for all candidates in the two catalogs. As a by-product we present a comparison between the DPOSS and SDSS surveys. This comparison is used to estimate the DPOSS detection limits. Some of the projects to be developed in the future are also discussed.

  19. Tensile Properties of Single Desmin Intermediate Filaments

    PubMed Central

    Kreplak, Laurent; Herrmann, Harald; Aebi, Ueli

    2008-01-01

    Within muscle fibers, desmin intermediate filaments (IFs) are major constituents of the extrasarcomeric cytoskeleton. However, their contribution to the mechanical properties of myocytes has remained elusive. We present an experimental approach to measure the extensibility and the tensile strength of in vitro reconstituted desmin IFs adsorbed to a solid support. The tip of an atomic force microscope (AFM) was used to push on single filaments perpendicular to the filament axis. The torque of the AFM cantilever was monitored during the pushing events to yield an estimate of the lateral force necessary to bend and stretch the filaments. Desmin IFs were stretched up to 3.4-fold with a maximum force of ∼3.5 nN. Fully stretched filaments exhibited a much smaller diameter than did native IFs, i.e., ∼3.5 nm compared to 12.6 nm, both by AFM and electron microscopy. Moreover, we combined the morphological and lateral force data to compute an average stress-strain curve for a single desmin filament. The main features were a pronounced strain-hardening regime above 50% extension and a tensile strength of at least 240 MPa. Because of these nonlinear tensile properties, desmin IFs may dissipate mechanical energy and serve as a physical link between successive sarcomeres during large deformation. PMID:18178641

  20. Understanding the White Dwarfs in Intermediate Polars

    NASA Astrophysics Data System (ADS)

    Belle, Kunegunda E.; Sion, E. M.

    2006-12-01

    The temperature of a white dwarf (WD) in a cataclysmic variable (CV) can tell you much about the accretion history of the binary system, and hence the evolution of the system. Best seen in the ultraviolet, a white dwarf's temperature is typically measured through modeling of a UV spectrum. This approach has been taken for numerous CVs modeling the spectrum as a combination of accretion disk and WD photosphere and also for polars, the strongly magnetic (B 10-80 MG) subset of CVs that contain magnetically controlled accretion streams rather than a disk. The task of extracting information about the WD in an intermediate polar (IP, magnetic CVs with B < 5 MG) is a bit trickier as they contain both magnetically controlled accretion streams and a truncated accretion disk. The fact that there are only five IPs for which WD temperatures have been estimated is a testament to the difficulty of modeling these systems. Here we present initial results from our project of determining the temperatures of WDs in IPs. We show that traditional methods of obtaining an inner accretion disk radius via optical emission line wings is likely inaccurate for most IPs, and that in some cases, the truncation radius is so large that the accretion disk does not contribute UV flux. Finally, we show that IPs follow the general trend of magnetic CVs containing cooler WDs than non-magnetic CVs. This work is supported in part by NSF grant AST0507514 and by NASA grant NNG04GE78G.

  1. Intermediate- and long-term earthquake prediction.

    PubMed

    Sykes, L R

    1996-04-30

    Progress in long- and intermediate-term earthquake prediction is reviewed emphasizing results from California. Earthquake prediction as a scientific discipline is still in its infancy. Probabilistic estimates that segments of several faults in California will be the sites of large shocks in the next 30 years are now generally accepted and widely used. Several examples are presented of changes in rates of moderate-size earthquakes and seismic moment release on time scales of a few to 30 years that occurred prior to large shocks. A distinction is made between large earthquakes that rupture the entire downdip width of the outer brittle part of the earth's crust and small shocks that do not. Large events occur quasi-periodically in time along a fault segment and happen much more often than predicted from the rates of small shocks along that segment. I am moderately optimistic about improving predictions of large events for time scales of a few to 30 years although little work of that type is currently underway in the United States. Precursory effects, like the changes in stress they reflect, should be examined from a tensorial rather than a scalar perspective. A broad pattern of increased numbers of moderate-size shocks in southern California since 1986 resembles the pattern in the 25 years before the great 1906 earthquake. Since it may be a long-term precursor to a great event on the southern San Andreas fault, that area deserves detailed intensified study.

  2. Intermediate- and long-term earthquake prediction.

    PubMed Central

    Sykes, L R

    1996-01-01

    Progress in long- and intermediate-term earthquake prediction is reviewed emphasizing results from California. Earthquake prediction as a scientific discipline is still in its infancy. Probabilistic estimates that segments of several faults in California will be the sites of large shocks in the next 30 years are now generally accepted and widely used. Several examples are presented of changes in rates of moderate-size earthquakes and seismic moment release on time scales of a few to 30 years that occurred prior to large shocks. A distinction is made between large earthquakes that rupture the entire downdip width of the outer brittle part of the earth's crust and small shocks that do not. Large events occur quasi-periodically in time along a fault segment and happen much more often than predicted from the rates of small shocks along that segment. I am moderately optimistic about improving predictions of large events for time scales of a few to 30 years although little work of that type is currently underway in the United States. Precursory effects, like the changes in stress they reflect, should be examined from a tensorial rather than a scalar perspective. A broad pattern of increased numbers of moderate-size shocks in southern California since 1986 resembles the pattern in the 25 years before the great 1906 earthquake. Since it may be a long-term precursor to a great event on the southern San Andreas fault, that area deserves detailed intensified study. Images Fig. 1 PMID:11607658

  3. Visualizing virus assembly intermediates inside marine cyanobacteria.

    PubMed

    Dai, Wei; Fu, Caroline; Raytcheva, Desislava; Flanagan, John; Khant, Htet A; Liu, Xiangan; Rochat, Ryan H; Haase-Pettingell, Cameron; Piret, Jacqueline; Ludtke, Steve J; Nagayama, Kuniaki; Schmid, Michael F; King, Jonathan A; Chiu, Wah

    2013-10-31

    Cyanobacteria are photosynthetic organisms responsible for ∼25% of organic carbon fixation on the Earth. These bacteria began to convert solar energy and carbon dioxide into bioenergy and oxygen more than two billion years ago. Cyanophages, which infect these bacteria, have an important role in regulating the marine ecosystem by controlling cyanobacteria community organization and mediating lateral gene transfer. Here we visualize the maturation process of cyanophage Syn5 inside its host cell, Synechococcus, using Zernike phase contrast electron cryo-tomography (cryoET). This imaging modality yields dramatic enhancement of image contrast over conventional cryoET and thus facilitates the direct identification of subcellular components, including thylakoid membranes, carboxysomes and polyribosomes, as well as phages, inside the congested cytosol of the infected cell. By correlating the structural features and relative abundance of viral progeny within cells at different stages of infection, we identify distinct Syn5 assembly intermediates. Our results indicate that the procapsid releases scaffolding proteins and expands its volume at an early stage of genome packaging. Later in the assembly process, we detected full particles with a tail either with or without an additional horn. The morphogenetic pathway we describe here is highly conserved and was probably established long before that of double-stranded DNA viruses infecting more complex organisms.

  4. Nucleoprotein complex intermediates in HIV-1 integration

    PubMed Central

    Li, Min; Craigie, Robert

    2012-01-01

    Integration of retroviral DNA into the host genome is an essential step in the viral replication cycle. The viral DNA, made by reverse transcription in the cytoplasm, forms part of a large nucleoprotein complex called the preintegration complex (PIC). The viral integrase protein is the enzyme within the PIC that is responsible for integrating the viral DNA into the host genome. Integrase is tightly associated with the viral DNA within the PIC as demonstrated by functional assays. Integrase protein catalyzes the key DNA cutting and joining steps of integration in vitro with DNA substrates that mimic the ends of the viral DNA. Under most in vitro assay conditions the stringency of the reaction is relaxed; most products result from “half-site” integration in which only one viral DNA end is integrated into one strand of target DNA rather than concerted integration of pairs of DNA as occurs with PICs and in vivo. Under these relaxed conditions catalysis appears to occur without formation of the highly stable nucleoprotein complexes that is characteristic of the association of integrase with viral DNA in the PIC. Here we describe methods for the assembly of nucleoprotein complex intermediates in HIV-1 DNA integration from purified HIV-1 integrase and substrates that mimic the viral DNA ends. PMID:19232539

  5. Grand unification and intermediate scale supersymmetry

    NASA Astrophysics Data System (ADS)

    Hall, Lawrence J.; Nomura, Yasunori

    2014-02-01

    With minimal field content and for an interesting range of the supersymmetric Higgs mixing parameter, 0.5 ≲ tan2 β ≲ 2, the superpartner mass scale, , is found to be at the intermediate scale, ~ 1010±1 GeV, near where the Standard Model Higgs quartic coupling passes through zero. For any 4d supersymmetric grand unified symmetry spontaneously broken by a vacuum expectation value <Σ>, if superpotential interactions for Σ are forbidden e.g. by R symmetries, the uneaten color octet, Σ8, and weak triplet, Σ3, have masses of order m. The combination of superpartner and Σ8,3 states leads to successful gauge coupling unification, removing the disastrously high proton decay rate of minimal Standard Model unification. Proton decay could be seen in future experiments if ~ 1011 GeV,but not if it is lower. If there heating temperature after inflation, T R , is less than dark matter may be axions. If T R > , thermal LSP dark matter may lead to the environmental selection of a TeV-scale LSP, either wino or Higgsino, which could comprise all or just one component of dark matter. In the Higgsino case, the dark matter is found to behave inelastically in direct detection experiments, and gauge coupling unification occurs accurately without the need of any threshold corrections.

  6. Superphenix 1 intermediate heat exchanger fabrication

    SciTech Connect

    Noel, H.; Granito, F.; Pouderoux, P.

    1985-02-01

    The eight Superphenix 375-MW (thermal) intermediate heat exchangers (IHXs) are similar in overall design to the Phenix components. Detailed design changes had to be made during fabrication on the following grounds: Due to seismic resistance, the support area was raised as high as possible to situate the component natural frequencies well out of the resonance peak range and remove thick plate-to-shell connections from heavy thermal load areas. Integration of lessons drawn from the Phenix incidents, due mainly to secondary sodium radial temperature disparities, resulted in the design of a more adaptable outlet header, together with a sodium mixing device, and in the reduction of temperature differences by heat insulation. To avoid circumferential temperature disparities, the iron shot biological shielding plug was replaced by stacked stainless steel plates within an outer shell, which in the new design, is not a supporting structure. The thermal-hydraulic and mechanical design of the component necessitated the elaboration of sophisticated computer codes, with validation of results on mock-ups. The detailed design studies and the actual manufacturing work had to adapt to both design developments and to inherent fabrication difficulties, mainly related to the very tight tolerances imposed for these exceptionally large components and to the welding of steel with an excessive boron content. The construction of the Creys-Malville IHXs afforded valuable industrial experience, which should provide a basis for the design of simpler and less costly IHX units for the forthcoming 1500-MW (electric) breeder.

  7. Intermediate Temperature Fluids Life Tests - Theory

    NASA Technical Reports Server (NTRS)

    Tarau, Calin; Sarraf, David B.; Locci, Ivan E.; Anderson, William G.

    2008-01-01

    There are a number of different applications that could use heat pipes or loop heat pipes (LHPs) in the intermediate temperature range of 450 to 750 K, including space nuclear power system radiators, and high temperature electronics cooling. Potential working fluids include organic fluids, elements, and halides, with halides being the least understood, with only a few life tests conducted. Potential envelope materials for halide working fluids include pure aluminum, aluminum alloys, commercially pure (CP) titanium, titanium alloys, and corrosion resistant superalloys. Life tests were conducted with three halides (AlBr3, SbBr3, and TiCl4) and water in three different envelopes: two aluminum alloys (Al-5052, Al-6061) and Cp-2 titanium. The AlBr3 attacked the grain boundaries in the aluminum envelopes, and formed TiAl compounds in the titanium. The SbBr3 was incompatible with the only envelope material that it was tested with, Al-6061. TiCl4 and water were both compatible with CP2-titanium. A theoretical model was developed that uses electromotive force differences to predict the compatibility of halide working fluids with envelope materials. This theory predicts that iron, nickel, and molybdenum are good envelope materials, while aluminum and titanium halides are good working fluids. The model is in good agreement with results form previous life tests, as well as the current life tests.

  8. Substrate radical intermediates in soluble methane monooxygenase.

    PubMed

    Liu, Aimin; Jin, Yi; Zhang, Jingyan; Brazeau, Brian J; Lipscomb, John D

    2005-12-09

    EPR spin-trapping experiments were carried out using the three-component soluble methane monooxygenase (MMO). Spin-traps 5,5-dimethyl-1-pyrroline N-oxide (DMPO), alpha-4-pyridyl-1-oxide N-tert-butylnitrone (POBN), and nitrosobenzene (NOB) were used to investigate the possible formation of substrate radical intermediates during catalysis. In contrast to a previous report, the NADH-coupled oxidations of various substrates did not produce any trapped radical species when DMPO or POBN was present. However, radicals were detected by these traps when only the MMO reductase component and NADH were present. DMPO and POBN were found to be weak inhibitors of the MMO reaction. In contrast, NOB is a strong inhibitor for the MMO-catalyzed nitrobenzene oxidation reaction. When NOB was used as a spin-trap in the complete MMO system with or without substrate, EPR signals from an NOB radical were detected. We propose that a molecule of NOB acts simultaneously as a substrate and a spin-trap for MMO, yielding the long-lived radical and supporting a stepwise mechanism for MMO.

  9. Rate control based on intermediate description

    NASA Astrophysics Data System (ADS)

    Liu, Meng; Guo, Yi; Li, Houqiang

    2010-07-01

    Video adaptation has been proved to be an efficient technique in dealing with various constraints such as bandwidth limitation and user requirement in multimedia applications. However, existing methods including Scalable Video Coding and transcoding cannot get a fine performance when bandwidth constraints exist in various scenarios particularly in realtime applications. In this paper, we propose a novel rate control scheme based on intermediate description. The proposed scheme can provide fast rate control for narrow and time-varying transmission channel in scenarios such as video streaming, video sharing and video on demand. In this scheme, Discrete Cosine Transform (DCT) coefficients distribution is modeled by generalized Gaussian distribution, meanwhile the parameter information of this model is stored as side information for rate control. With the stored parameter information, encoder and transcoder can achieve the target bit-rate with low complexity. Furthermore, an initial Quantization Parameter (QP) determination method is also presented to calculate a proper QP for the Instantaneous Decoding Refresh (IDR) picture. Experimental results show that compared with JVT-G012 in H.264, the proposed rate control scheme can save more than 85% encoding time and obtain the required bit-rate more precisely, meanwhile gains a performance improvement by 0.2dB averagely.

  10. Wind Variability in Intermediate Luminosity B Supergiants

    NASA Technical Reports Server (NTRS)

    Massa, Derck

    1996-01-01

    This study used the unique spectroscopic diagnostics of intermediate luminosity B supergiants to determine the ubiquity and nature of wind variability. Specifically, (1) A detailed analysis of HD 64760 demonstrated massive ejections into its wind, provided the first clear demonstration of a 'photospheric connection' and ionization shifts in a stellar wind; (2) The international 'IUE MEGA campaign' obtained unprecedented temporal coverage of wind variability in rapidly rotating stars and demonstrated regularly repeating wind features originating in the photosphere; (3) A detailed analysis of wind variability in the rapidly rotating B1 Ib, gamma Ara demonstrated a two component wind with distinctly different mean states at different epochs; (4) A follow-on campaign to the MEGA project to study slowly rotating stars was organized and deemed a key project by ESA/NASA, and will obtain 30 days of IUE observations in May-June 1996; and (5) A global survey of archival IUE time series identified recurring spectroscopic signatures, identified with different physical phenomena. Items 4 and 5 above are still in progress and will be completed this summer in collaboration with Raman Prinja at University College, London.

  11. Intermediate Temperature Fluids Life Tests - Theory

    NASA Technical Reports Server (NTRS)

    Tarau, Calin; Sarraf, David B.; Locci, Ivan E.; Anderson, William G.

    2008-01-01

    There are a number of different applications that could use heat pipes or loop heat pipes (LHPs) in the intermediate temperature range of 450 to 750 K, including space nuclear power system radiators, and high temperature electronics cooling. Potential working fluids include organic fluids, elements, and halides, with halides being the least understood, with only a few life tests conducted. Potential envelope materials for halide working fluids include pure aluminum, aluminum alloys, commercially pure (CP) titanium, titanium alloys, and corrosion resistant superalloys. Life tests were conducted with three halides (AlBr3, SbBr3, and TiCl4) and water in three different envelopes: two aluminum alloys (Al-5052, Al-6061) and Cp-2 titanium. The AlBr3 attacked the grain boundaries in the aluminum envelopes, and formed TiAl compounds in the titanium. The SbBr3 was incompatible with the only envelope material that it was tested with, Al-6061. TiCl4 and water were both compatible with CP2-titanium. A theoretical model was developed that uses electromotive force differences to predict the compatibility of halide working fluids with envelope materials. This theory predicts that iron, nickel, and molybdenum are good envelope materials, while aluminum and titanium halides are good working fluids. The model is in good agreement with results form previous life tests, as well as the current life tests.

  12. Immunopathology of the noninfectious posterior and intermediate uveitides.

    PubMed

    Boyd, S R; Young, S; Lightman, S

    2001-01-01

    The posterior and intermediate uveitides share an underlying immune etiology; however, they can be clinically and immunopathologically distinguished. Although the initiating stimuli for posterior and intermediate uveities are not known, it is believed that an exogenous agent (such as a bacterium or a virus) or an endogenous molecule may induce disease. In either case, T-helper lymphocytes in conjunction with human leukocyte antigens are likely to be involved. This review examines the epidemiology, histology, immunopathology, and theories of pathogenesis of several posterior and intermediate uveitides, including sympathetic ophthalmia, Vogt-Koyanagi-Harada syndrome, Behçet's disease, sarcoidosis, intermediate uveitis, white dot syndromes, and birdshot retinochoroidopathy.

  13. Intermediate frequency magnetic field and chick embryotoxicity.

    PubMed

    Nishimura, Izumi; Tanaka, Keiko; Negishi, Tadashi

    2013-09-01

    Intermediate frequency magnetic fields (MFs) have widely been used in industrial machines and home appliances, such as induction heating cookers, although toxicity studies to evaluate the potential health risks of such fields are insufficient. In induction heating cookers, the MF source (i.e. hobs), is located near the abdominal position of a person cooking. Hence, developmental effects on the fetus may be a concern in case the person is a pregnant woman. Fertile White Leghorn eggs (60/group) were either exposed to 20 kHz, 1.1 mT(rms) or 60 kHz, 0.11 mT(rms) sinusoidal MFs for 19 days during embryogenesis. The same number of eggs served as a control group. In addition, a sham-sham experiment was conducted to validate the equality between exposure and control facilities. After exposure, embryos were examined for mortality rate and stage. Live embryos were evaluated for developmental stage and gross and skeletal anomalies. Length of upper beak and leg digits was also measured. Examinations were conducted in a blinded fashion to ensure quality assurance; experiments were triplicated for each frequency to confirm the outcome reproducibility. Mortality rate and stage, incidence of malformed embryos, and developmental variables in live embryos were found to be similar between the MF-exposed and corresponding control group. Incidence of gross anomalies such as mandibular edema and skeletal anomalies such as coccyx defects were low across the experiments, and no significant group differences were noted. In conclusion, exposure to 20 kHz or 60 kHz MF did not produce any significant teratogenic developmental effects in chick embryos.

  14. Intermediate Temperature Fluids Life Tests - Experiments

    NASA Technical Reports Server (NTRS)

    Anderson, William G.; Bonner, Richard W.; Dussinger, Peter M.; Hartenstine, John R.; Sarraf, David B.; Locci, Ivan E.

    2007-01-01

    There are a number of different applications that could use heat pipes or loop heat pipes (LHPs) in the intermediate temperature range of 450 to 725 K (170 to 450 C), including space nuclear power system radiators, fuel cells, and high temperature electronics cooling. Historically, water has been used in heat pipes at temperatures up to about 425 K (150 C). Recent life tests, updated below, demonstrate that titanium/water and Monel/water heat pipes can be used at temperatures up to 550 K (277 C), due to water's favorable transport properties. At temperatures above roughly 570 K (300 C), water is no longer a suitable fluid, due to high vapor pressure and low surface tension as the critical point is approached. At higher temperatures, another working fluid/envelope combination is required, either an organic or halide working fluid. An electromotive force method was used to predict the compatibility of halide working fluids with envelope materials. This procedure was used to reject aluminum and aluminum alloys as envelope materials, due to their high decomposition potential. Titanium and three corrosion resistant superalloys were chosen as envelope materials. Life tests were conducted with these envelopes and six different working fluids: AlBr3, GaCl3, SnCl4, TiCl4, TiBr4, and eutectic diphenyl/diphenyl oxide (Therminol VP-1/Dowtherm A). All of the life tests except for the GaCl3 are ongoing; the GaCl3 was incompatible. As the temperature approaches 725 K (450 C), cesium is a potential heat pipe working fluid. Life tests results are also presented for cesium/Monel 400 and cesium/70-30 copper/nickel heat pipes operating near 750 K (477 C). These materials are not suitable for long term operation, due to copper transport from the condenser to the evaporator.

  15. 19. VIEW SOUTHWEST OF INTERMEDIATE VERTICAL PENNSYLVANIA PETIT TRUSS WITH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    19. VIEW SOUTHWEST OF INTERMEDIATE VERTICAL PENNSYLVANIA PETIT TRUSS WITH CASTLE ROCK IN BACKGROUND. JUNCTION OF INTERMEDIATE VERTICAL AND TOP CHORD WITH STABILIZING LATERAL STRUT ABOVE AND SWAY STRUT BELOW. ORIGINAL PAIRED DIAGONAL EYE BARS LATER REINFORCED WITH TIE ROD - New River Bridge, Spanning New River at State Route 623, Pembroke, Giles County, VA

  16. The Needs of Intermediate Professions: Middle Engineers and Middle Managers.

    ERIC Educational Resources Information Center

    Le Nouvel, Jean

    In France, intermediate professions are jobs for holders of the professional baccalaureate plus 2-4 years of additional study. Intermediate technological education supplies a qualification that comes between secondary education and the qualified engineer. These people have a practical background that combines knowledge with skills and an ability…

  17. Possible Source of Intermediate Ions over Marine Environment

    PubMed Central

    Pawar, Sunil D.; Gopalakrishnan, V.

    2012-01-01

    Measurements of small, intermediate and large ions made onboard ORV Sagarkanya over the Arabian Sea in May-June 2003 during Arabian Sea Monsoon Experiment (ARMEX) are reported here. The daily averaged values of small-, intermediate-, and large-ion concentrations measured for 36 days during this cruise have been used for analysis. The analysis shows a weak positive correlation of 0.14 between intermediate- and large-ion concentrations, which indicates that the sources of these two types of ions are different over ocean surface. The negative correlation is observed between small- and intermediate-ion concentration for entire period of cruise. In addition, it is seen that the intermediate-ion concentration shows a very good (r = 0.58) and significant positive correlation with sea surface pressure. Based on good negative correlation between small- and intermediate-ion concentrations and good positive correlation between intermediate-ion concentration and sea surface pressure, it has been proposed that attachment of small ions to the ultrafine particles transported from upper troposphere to marine boundary layer is the main source of intermediate ions over ocean surface. This study supports the idea that the main source of ultrafine particles over marine boundary layer (MBL) is entrainment of aerosol particles from the free troposphere. PMID:22701357

  18. 9 CFR 2.77 - Records: Carriers and intermediate handlers.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Records: Carriers and intermediate handlers. 2.77 Section 2.77 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE REGULATIONS Records § 2.77 Records: Carriers and intermediate...

  19. 9 CFR 2.77 - Records: Carriers and intermediate handlers.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Records: Carriers and intermediate handlers. 2.77 Section 2.77 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE REGULATIONS Records § 2.77 Records: Carriers and intermediate...

  20. "Affective Encounters": Live Intermedial Spaces in Sites of Trauma

    ERIC Educational Resources Information Center

    Scott, Jo

    2016-01-01

    This article addresses live intermediality as a tool for creative learning in the context of workshops carried out with young people in the town of Terezin, in the Czech Republic, site of the Nazi concentration camp, Theresienstadt. Live intermediality, as a mode of live media practice, involves the real time mixing and merging of sound, image,…

  1. 27 CFR 17.154 - Spirits contained in intermediate products.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS DRAWBACK ON TAXPAID DISTILLED SPIRITS USED IN MANUFACTURING NONBEVERAGE PRODUCTS Claims for Drawback Spirits Subject to Drawback § 17.154 Spirits contained in intermediate products. Spirits contained in an intermediate product are not subject to drawback until that...

  2. Digital Intermediation: An Exploration of User and Intermediary Perspectives.

    ERIC Educational Resources Information Center

    Southwick, Silvia Barcellos

    2003-01-01

    Reports on an exploratory case study of intermediation in a hospital digital library information service. Focuses on intermediation where user-intermediary communications were conducted through an asynchronous text-based digital medium. Contributions of the study are evidenced in a descriptive framework of nine categories of factors perceived as…

  3. 27 CFR 17.126 - Formulas for intermediate products.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... which that ingredient is used, or unless the formula for the ingredient is contained in one of the... 27 Alcohol, Tobacco Products and Firearms 1 2012-04-01 2012-04-01 false Formulas for intermediate... NONBEVERAGE PRODUCTS Formulas and Samples § 17.126 Formulas for intermediate products. (a) The manufacturer...

  4. 27 CFR 17.126 - Formulas for intermediate products.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... which that ingredient is used, or unless the formula for the ingredient is contained in one of the... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Formulas for intermediate... NONBEVERAGE PRODUCTS Formulas and Samples § 17.126 Formulas for intermediate products. (a) The manufacturer...

  5. 27 CFR 17.126 - Formulas for intermediate products.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... which that ingredient is used, or unless the formula for the ingredient is contained in one of the... 27 Alcohol, Tobacco Products and Firearms 1 2014-04-01 2014-04-01 false Formulas for intermediate... NONBEVERAGE PRODUCTS Formulas and Samples § 17.126 Formulas for intermediate products. (a) The manufacturer...

  6. 29 CFR 452.81 - Rights in intermediate body elections.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 2 2010-07-01 2010-07-01 false Rights in intermediate body elections. 452.81 Section 452... REPORTING AND DISCLOSURE ACT OF 1959 Campaign Safeguards § 452.81 Rights in intermediate body elections. While the literal language in section 401(c) relating to distribution of campaign literature and to...

  7. Borderline Personality Disorder in an Intermediate Psychological Therapies Service

    ERIC Educational Resources Information Center

    Ryan, Seamus; Danquah, Adam N.; Berry, Katherine; Hopper, Mary

    2017-01-01

    The intermediate psychological therapies service is provided for individuals referred with common mental health problems within the primary care psychological therapies service, but whose difficulties are longstanding and/or complex. The prevalence of borderline personality disorder (BPD) in intermediate psychological therapy services has not been…

  8. 42 CFR 54a.12 - Treatment of intermediate organizations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Treatment of intermediate organizations. 54a.12 Section 54a.12 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS... ABUSE PREVENTION AND TREATMENT SERVICES § 54a.12 Treatment of intermediate organizations. If a...

  9. 42 CFR 54a.12 - Treatment of intermediate organizations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Treatment of intermediate organizations. 54a.12 Section 54a.12 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS... ABUSE PREVENTION AND TREATMENT SERVICES § 54a.12 Treatment of intermediate organizations. If a...

  10. 42 CFR 54a.12 - Treatment of intermediate organizations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Treatment of intermediate organizations. 54a.12 Section 54a.12 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS... ABUSE PREVENTION AND TREATMENT SERVICES § 54a.12 Treatment of intermediate organizations. If a...

  11. 29 CFR 452.81 - Rights in intermediate body elections.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 2 2014-07-01 2014-07-01 false Rights in intermediate body elections. 452.81 Section 452... REPORTING AND DISCLOSURE ACT OF 1959 Campaign Safeguards § 452.81 Rights in intermediate body elections. While the literal language in section 401(c) relating to distribution of campaign literature and to...

  12. "Intermediate" seed storage physiology: populus as a natural model system

    USDA-ARS?s Scientific Manuscript database

    “Intermediate” seeds are short lived because they are sensitive to the combined stresses of low moisture and temperature during storage. We hypothesize that intermediate seeds either 1) exhibit intermediate sensitivity to desiccation compared to orthodox and recalcitrant seeds; 2) are damaged by sub...

  13. "Affective Encounters": Live Intermedial Spaces in Sites of Trauma

    ERIC Educational Resources Information Center

    Scott, Jo

    2016-01-01

    This article addresses live intermediality as a tool for creative learning in the context of workshops carried out with young people in the town of Terezin, in the Czech Republic, site of the Nazi concentration camp, Theresienstadt. Live intermediality, as a mode of live media practice, involves the real time mixing and merging of sound, image,…

  14. 21 CFR 312.315 - Intermediate-size patient populations.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 5 2013-04-01 2013-04-01 false Intermediate-size patient populations. 312.315... for Treatment Use § 312.315 Intermediate-size patient populations. Under this section, FDA may permit an investigational drug to be used for the treatment of a patient population smaller than that...

  15. 21 CFR 312.315 - Intermediate-size patient populations.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 5 2014-04-01 2014-04-01 false Intermediate-size patient populations. 312.315... for Treatment Use § 312.315 Intermediate-size patient populations. Under this section, FDA may permit an investigational drug to be used for the treatment of a patient population smaller than that...

  16. 21 CFR 312.315 - Intermediate-size patient populations.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 5 2012-04-01 2012-04-01 false Intermediate-size patient populations. 312.315... for Treatment Use § 312.315 Intermediate-size patient populations. Under this section, FDA may permit an investigational drug to be used for the treatment of a patient population smaller than that...

  17. 21 CFR 312.315 - Intermediate-size patient populations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 5 2011-04-01 2011-04-01 false Intermediate-size patient populations. 312.315... for Treatment Use § 312.315 Intermediate-size patient populations. Under this section, FDA may permit an investigational drug to be used for the treatment of a patient population smaller than that...

  18. 21 CFR 312.315 - Intermediate-size patient populations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Intermediate-size patient populations. 312.315... for Treatment Use § 312.315 Intermediate-size patient populations. Under this section, FDA may permit an investigational drug to be used for the treatment of a patient population smaller than that...

  19. 29 CFR 452.81 - Rights in intermediate body elections.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 2 2012-07-01 2012-07-01 false Rights in intermediate body elections. 452.81 Section 452... REPORTING AND DISCLOSURE ACT OF 1959 Campaign Safeguards § 452.81 Rights in intermediate body elections. While the literal language in section 401(c) relating to distribution of campaign literature and to...

  20. 29 CFR 452.81 - Rights in intermediate body elections.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 2 2011-07-01 2011-07-01 false Rights in intermediate body elections. 452.81 Section 452... REPORTING AND DISCLOSURE ACT OF 1959 Campaign Safeguards § 452.81 Rights in intermediate body elections. While the literal language in section 401(c) relating to distribution of campaign literature and to...

  1. Incoherence in the South African Labour Market for Intermediate Skills

    ERIC Educational Resources Information Center

    Kraak, Andre

    2008-01-01

    This article is concerned with the production and employment of technically skilled labour at the intermediate level in South Africa. Three differing labour market pathways to intermediate skilling are identified. These are: the traditional apprenticeship route, the new "Learnerships" pathway (similar to the "modern…

  2. Thermolabile folding intermediates: inclusion body precursors and chaperonin substrates

    PubMed Central

    KING, JONATHAN; HAASE-PETTINGELL, CAMERON; ROBINSON, ANNE SKAJA; SPEED, MARGARET; MITRAKI, ANNA

    2007-01-01

    An unexpected aspect of the expression of cloned genes is the frequent failure of newly synthesized polypeptide chains to reach their native state, accumulating instead as insoluble inclusion bodies. Amyloid deposits represent a related state associated with a variety of human diseases. The critical folding intermediates at the juncture of productive folding and the off-pathway aggregation reaction have been identified for the phage P22 tailspike and coat proteins. Though the parallel β coil tailspike is thermostable, an early intracellular folding intermediate is thermolabile. As the temperature of intracellular folding is increased, this species partitions to inclusion bodies, a kinetic trap within the cell. The earliest intermediates along the in vitro aggregation pathway, sequential multimers of the thermolabile folding intermediates, have been directly identified by native gel electrophoresis. Temperature-sensitive folding (tsf) mutations identify sites in the β coil domain, which direct the junctional intermediate down the productive pathway. Global suppressors of tsf mutants inhibit the pathway to inclusion bodies, rescuing the mutant chains. These mutants identify sites important for avoiding aggregation. Coat folding intermediates also partition to inclusion bodies as temperature is increased. Coat tsf mutants are suppressed by overexpression of the GroE chaperonin, indicating that the thermolabile intermediate is a physiological substrate for GroE. We suggest that many proteins are likely to have thermolabile intermediates in their intracellular folding pathways, which will be precursors to inclusion body formation at elevated temperatures and therefore substrates for heat shock chaperonins. PMID:8566549

  3. 42 CFR 438.702 - Types of intermediate sanctions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Types of intermediate sanctions. 438.702 Section 438.702 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS MANAGED CARE Sanctions § 438.702 Types of intermediate...

  4. Intermediate mass fragment production in central collisions of intermediate energy heavy ions

    SciTech Connect

    Li, T.; Bauer, W.; Craig, D.; Cronqvist, M.; Gualtieri, E.; Hannuschke, S.; Lacey, R.; Llope, W.J.; Reposeur, T.; Vander Molen, A.M.; Westfall, G.D.; Wilson, W.K.; Winfield, J.S.; Yee, J.; Yennello, S.J. ); Nadasen, A. ); Tickle, R.S. ); Norbeck, E. )

    1993-03-29

    We present [ital Z] distributions for fragments with 1[le][ital Z][le]12 from central collisions of [sup 40] Ar+[sup 45]Sc at incident energies ranging from 35 to 115 MeV/nucleon. We find that the [ital Z] distributions can be described by a power law or an exponential and steepen with increasing incident energy. Over the range of incident energies studied, the average number of intermediate mass fragments decreases while the average number of particles increases. When combined with previous results for the charge distributions, a minimum is observed in the extracted power-law parameter.

  5. Healthy Schools

    MedlinePlus

    ... for Healthy Schools School Health Guidelines Data & Statistics Multimedia Infographics Podcasts Videos Professional Development & Training Professional Development 101 Professional Development 201 FAQs E-Learning Series: Training Tools for Healthy Schools Comprehensive School ...

  6. Intermediate Filaments and Polarization in the Intestinal Epithelium

    PubMed Central

    Coch, Richard A.; Leube, Rudolf E.

    2016-01-01

    The cytoplasmic intermediate filament cytoskeleton provides a tissue-specific three-dimensional scaffolding with unique context-dependent organizational features. This is particularly apparent in the intestinal epithelium, in which the intermediate filament network is localized below the apical terminal web region and is anchored to the apical junction complex. This arrangement is conserved from the nematode Caenorhabditis elegans to humans. The review summarizes compositional, morphological and functional features of the polarized intermediate filament cytoskeleton in intestinal cells of nematodes and mammals. We emphasize the cross talk of intermediate filaments with the actin- and tubulin-based cytoskeleton. Possible links of the intermediate filament system to the distribution of apical membrane proteins and the cell polarity complex are highlighted. Finally, we discuss how these properties relate to the establishment and maintenance of polarity in the intestine. PMID:27429003

  7. Regional boreal biodiversity peaks at intermediate human disturbance.

    PubMed

    Mayor, S J; Cahill, J F; He, F; Sólymos, P; Boutin, S

    2012-01-01

    The worldwide biodiversity crisis has intensified the need to better understand how biodiversity and human disturbance are related. The 'intermediate disturbance hypothesis' suggests that disturbance regimes generate predictable non-linear patterns in species richness. Evidence often contradicts intermediate disturbance hypothesis at small scales, and is generally lacking at large regional scales. Here, we present the largest extent study of human impacts on boreal plant biodiversity to date. Disturbance extent ranged from 0 to 100% disturbed in vascular plant communities, varying from intact forest to agricultural fields, forestry cut blocks and oil sands. We show for the first time that across a broad region species richness peaked in communities with intermediate anthropogenic disturbance, as predicted by intermediate disturbance hypothesis, even when accounting for many environmental covariates. Intermediate disturbance hypothesis was consistently supported across trees, shrubs, forbs and grasses, with temporary and perpetual disturbances. However, only native species fit this pattern; exotic species richness increased linearly with disturbance.

  8. Intermediate Water Radiocarbon Anomalies During the Last Deglaciation

    NASA Astrophysics Data System (ADS)

    Bryan, S. P.; Lehman, S. J.; Marchitto, T. M.; Ninnemann, U. S.

    2011-12-01

    Several recent reconstructions of intermediate water radiocarbon activities (Δ14C) have revealed intervals of very low Δ14C during the last deglaciation [Bryan et al., 2010; Marchitto et al., 2007; Thornalley et al., 2011]. Anomalously low Δ14C values coincided with increases in atmospheric CO2 and decreases in atmospheric Δ14C. As such, these Δ14C anomalies have been interpreted as the transfer of 14C-depleted carbon from the deep ocean to the upper ocean and atmosphere. An important component of this interpretation is the transport of low-Δ14C waters from the Southern Ocean, where they presumably upwelled from the deep ocean, northward to the core sites via intermediate waters. However, contrary to expectations, anomalously low Δ14C values have not been found at intermediate water sites closer to the Southern Ocean [e.g., De Pol-Holz et al., 2009; Rose et al., 2010]. In this talk, we will present new intermediate water Δ14C measurements from ~53°S along the Chile Margin, reconstructed using sediment core MD07-3128. Consistent with other intermediate water records from the Southern Hemisphere, these measurements do not show anomalously low Δ14C during the deglaciation. Instead, these results indicate lower Δ14C values during the Last Glacial Maximum and a rapid increase in Δ14C at the start of the deglaciation. We interpret this change as a shift in the boundary between Circumpolar Deep Water and Antarctic Intermediate Water. These results along with the previously published records provide strong evidence that low-Δ14C waters were not transported by an intermediate water mass analogous to modern Antarctic Intermediate Water. We synthesize the currently available deglacial intermediate water Δ14C records and discuss possible changes to Southern Ocean intermediate water formation, which could reconcile the available data.

  9. The Intermediate Complexity Atmospheric Research Model

    NASA Astrophysics Data System (ADS)

    Gutmann, Ethan; Clark, Martyn; Rasmussen, Roy; Arnold, Jeffrey; Brekke, Levi

    2015-04-01

    The high-resolution, non-hydrostatic atmospheric models often used for dynamical downscaling are extremely computationally expensive, and, for a certain class of problems, their complexity hinders our ability to ask key scientific questions, particularly those related to hydrology and climate change. For changes in precipitation in particular, an atmospheric model grid spacing capable of resolving the structure of mountain ranges is of critical importance, yet such simulations can not currently be performed with an advanced regional climate model for long time periods, over large areas, and forced by many climate models. Here we present the newly developed Intermediate Complexity Atmospheric Research model (ICAR) capable of simulating critical atmospheric processes two to three orders of magnitude faster than a state of the art regional climate model. ICAR uses a simplified dynamical formulation based off of linear theory, combined with the circulation field from a low-resolution climate model. The resulting three-dimensional wind field is used to advect heat and moisture within the domain, while sub-grid physics (e.g. microphysics) are processed by standard and simplified physics schemes from the Weather Research and Forecasting (WRF) model. ICAR is tested in comparison to WRF by downscaling a climate change scenario over the Colorado Rockies. Both atmospheric models predict increases in precipitation across the domain with a greater increase on the western half. In contrast, statistically downscaled precipitation using multiple common statistical methods predict decreases in precipitation over the western half of the domain. Finally, we apply ICAR to multiple CMIP5 climate models and scenarios with multiple parameterization options to investigate the importance of uncertainty in sub-grid physics as compared to the uncertainty in the large scale climate scenario. ICAR is a useful tool for climate change and weather forecast downscaling, particularly for orographic

  10. Intermediate coupled superconductivity in yttrium intermetallics

    NASA Astrophysics Data System (ADS)

    Sharma, Ramesh; Ahmed, Gulzar; Sharma, Yamini

    2017-09-01

    -atom in the YIn3 lattice further consolidates the superconducting nature due to increase in N(EF) and γ (electronic component of specific heat), along with lowering of the frequency of imaginary modes from 5.6 THz to 1.5-0.6 THz. Thus Tc is directly related to the valence electron concentration and ternary YIn2Sn may exhibit intermediate superconducting transition temperature.

  11. Nuclear structure at intermediate energies. Progress report

    SciTech Connect

    Bonner, B.E.; Mutchler, G.S.

    1992-07-15

    We report here oil the progress that we made for the nine months beginning October 1, 1991 for DOE Grant No. DE-FG05-87ER40309. The report covers the third year of a three year grant. Since we are submitting an accompanying Grant Renewal Proposal, we provide in this report more background information than usual for the different projects. The theme that unites the experiments undertaken by the Bonner Lab Medium Energy Group is a determination to understand in detail the many facets and manifestations of the strong interaction, that which is now referred to as nonperturbative QCD. Whether we are investigating the question of just what does carry the spin of baryons, or the extent of the validity of the SU(6) wavefunctions for the excited hyperons (as will be measured in our CEBAF experiment), or questions associated with the formation of a new state of matter predicted by QCD (the subject of AGS {bar p} experiment E854, AGS heavy ion experiment E810, as-well as the approved STAR experiment at RHIC), - all these projects share this common goal. FNAL E683 may well open a new field of investigation in nuclear physics: That of just how colored quarks and gluons interact with nuclear matter as they traverse nuclei of different-sizes. In most all of the experiments mentioned, above, the Bonner Lab Group is playing major leadership roles as well as doing a big fraction of the hard work that such experiments require. We use many of the facilities that are available to the intermediate energy physics community and we use our expertise to design and fabricate the detectors and instrumentation that are required to perform the measurements which we decide to do. The format we follow in the Progress Report is,to provide a concise, but fairly complete write-up on each project. The publications listed in Section In give much greater detail on many of the projects. The aim in this report is to focus on the physics goals, the results, and their significance.

  12. Dorsoventral patterning in the Drosophila central nervous system: the intermediate neuroblasts defective homeobox gene specifies intermediate column identity

    PubMed Central

    Weiss, Joseph B.; Von Ohlen, Tonia; Mellerick, Dervla M.; Dressler, Gregory; Doe, Chris Q.; Scott, Matthew P.

    1998-01-01

    One of the first steps in neurogenesis is the diversification of cells along the dorsoventral axis. In Drosophila the central nervous system develops from three longitudinal columns of cells: ventral cells that express the vnd/nk2 homeobox gene, intermediate cells, and dorsal cells that express the msh homeobox gene. Here we describe a new Drosophila homeobox gene, intermediate neuroblasts defective (ind), which is expressed specifically in the intermediate column cells. ind is essential for intermediate column development: Null mutants have a transformation of intermediate to dorsal column neuroectoderm fate, and only 10% of the intermediate column neuroblasts develop. The establishment of dorsoventral column identity involves negative regulation: Vnd represses ind in the ventral column, whereas ind represses msh in the intermediate column. Vertebrate genes closely related to vnd (Nkx2.1 and Nkx2.2), ind (Gsh1 and Gsh2), and msh (Msx1 and Msx3) are expressed in corresponding ventral, intermediate, and dorsal domains during vertebrate neurogenesis, raising the possibility that dorsoventral patterning within the central nervous system is evolutionarily conserved. PMID:9832510

  13. 49 CFR 222.42 - How does this rule affect Intermediate Quiet Zones and Intermediate Partial Quiet Zones?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... and Intermediate Partial Quiet Zones? 222.42 Section 222.42 Transportation Other Regulations Relating... Horns at Groups of Crossings-Quiet Zones § 222.42 How does this rule affect Intermediate Quiet Zones and..., if the public authority provides Notice of Quiet Zone Continuation, in accordance with § 222.43...

  14. Mediation Analysis With Intermediate Confounding: Structural Equation Modeling Viewed Through the Causal Inference Lens

    PubMed Central

    De Stavola, Bianca L.; Daniel, Rhian M.; Ploubidis, George B.; Micali, Nadia

    2015-01-01

    The study of mediation has a long tradition in the social sciences and a relatively more recent one in epidemiology. The first school is linked to path analysis and structural equation models (SEMs), while the second is related mostly to methods developed within the potential outcomes approach to causal inference. By giving model-free definitions of direct and indirect effects and clear assumptions for their identification, the latter school has formalized notions intuitively developed in the former and has greatly increased the flexibility of the models involved. However, through its predominant focus on nonparametric identification, the causal inference approach to effect decomposition via natural effects is limited to settings that exclude intermediate confounders. Such confounders are naturally dealt with (albeit with the caveats of informality and modeling inflexibility) in the SEM framework. Therefore, it seems pertinent to revisit SEMs with intermediate confounders, armed with the formal definitions and (parametric) identification assumptions from causal inference. Here we investigate: 1) how identification assumptions affect the specification of SEMs, 2) whether the more restrictive SEM assumptions can be relaxed, and 3) whether existing sensitivity analyses can be extended to this setting. Data from the Avon Longitudinal Study of Parents and Children (1990–2005) are used for illustration. PMID:25504026

  15. Mediation analysis with intermediate confounding: structural equation modeling viewed through the causal inference lens.

    PubMed

    De Stavola, Bianca L; Daniel, Rhian M; Ploubidis, George B; Micali, Nadia

    2015-01-01

    The study of mediation has a long tradition in the social sciences and a relatively more recent one in epidemiology. The first school is linked to path analysis and structural equation models (SEMs), while the second is related mostly to methods developed within the potential outcomes approach to causal inference. By giving model-free definitions of direct and indirect effects and clear assumptions for their identification, the latter school has formalized notions intuitively developed in the former and has greatly increased the flexibility of the models involved. However, through its predominant focus on nonparametric identification, the causal inference approach to effect decomposition via natural effects is limited to settings that exclude intermediate confounders. Such confounders are naturally dealt with (albeit with the caveats of informality and modeling inflexibility) in the SEM framework. Therefore, it seems pertinent to revisit SEMs with intermediate confounders, armed with the formal definitions and (parametric) identification assumptions from causal inference. Here we investigate: 1) how identification assumptions affect the specification of SEMs, 2) whether the more restrictive SEM assumptions can be relaxed, and 3) whether existing sensitivity analyses can be extended to this setting. Data from the Avon Longitudinal Study of Parents and Children (1990-2005) are used for illustration.

  16. Perspective: Spectroscopy and kinetics of small gaseous Criegee intermediates.

    PubMed

    Lee, Yuan-Pern

    2015-07-14

    The Criegee intermediates, carbonyl oxides proposed by Criegee in 1949 as key intermediates in the ozonolysis of alkenes, play important roles in many aspects of atmospheric chemistry. Because direct detection of these gaseous intermediates was unavailable until recently, previous understanding of their reactions, derived from indirect experimental evidence, had great uncertainties. Recent laboratory detection of the simplest Criegee intermediate CH2OO and some larger members, produced from ultraviolet irradiation of corresponding diiodoalkanes in O2, with various methods such as photoionization, ultraviolet absorption, infrared absorption, and microwave spectroscopy opens a new door to improved understanding of the roles of these Criegee intermediates. Their structures and spectral parameters have been characterized; their significant zwitterionic nature is hence confirmed. CH2OO, along with other products, has also been detected directly with microwave spectroscopy in gaseous ozonolysis reactions of ethene. The detailed kinetics of the source reaction, CH2I + O2, which is critical to laboratory studies of CH2OO, are now understood satisfactorily. The kinetic investigations using direct detection identified some important atmospheric reactions, including reactions with NO2, SO2, water dimer, carboxylic acids, and carbonyl compounds. Efforts toward the characterization of larger Criegee intermediates and the investigation of related reactions are in progress. Some reactions of CH3CHOO are found to depend on conformation. This perspective examines progress toward the direct spectral characterization of Criegee intermediates and investigations of the associated reaction kinetics, and indicates some unresolved problems and prospective challenges for this exciting field of research.

  17. Perspective: Spectroscopy and kinetics of small gaseous Criegee intermediates

    NASA Astrophysics Data System (ADS)

    Lee, Yuan-Pern

    2015-07-01

    The Criegee intermediates, carbonyl oxides proposed by Criegee in 1949 as key intermediates in the ozonolysis of alkenes, play important roles in many aspects of atmospheric chemistry. Because direct detection of these gaseous intermediates was unavailable until recently, previous understanding of their reactions, derived from indirect experimental evidence, had great uncertainties. Recent laboratory detection of the simplest Criegee intermediate CH2OO and some larger members, produced from ultraviolet irradiation of corresponding diiodoalkanes in O2, with various methods such as photoionization, ultraviolet absorption, infrared absorption, and microwave spectroscopy opens a new door to improved understanding of the roles of these Criegee intermediates. Their structures and spectral parameters have been characterized; their significant zwitterionic nature is hence confirmed. CH2OO, along with other products, has also been detected directly with microwave spectroscopy in gaseous ozonolysis reactions of ethene. The detailed kinetics of the source reaction, CH2I + O2, which is critical to laboratory studies of CH2OO, are now understood satisfactorily. The kinetic investigations using direct detection identified some important atmospheric reactions, including reactions with NO2, SO2, water dimer, carboxylic acids, and carbonyl compounds. Efforts toward the characterization of larger Criegee intermediates and the investigation of related reactions are in progress. Some reactions of CH3CHOO are found to depend on conformation. This perspective examines progress toward the direct spectral characterization of Criegee intermediates and investigations of the associated reaction kinetics, and indicates some unresolved problems and prospective challenges for this exciting field of research.

  18. Schools within Schools. ERIC Digest.

    ERIC Educational Resources Information Center

    McAndrews, Tobin; Anderson, Wendell

    Schools within schools are large public schools that have been divided into smaller autonomous subunits to create a sense of community and cohesiveness among students and staff. This digest discusses the benefits, drawbacks, varieties, and sources of funding for schools within schools. Designers of these schools seek the advantages of both large…

  19. Multiple Case Studies of Literacy Practices Utilized by Intermediate Grade Teachers Which Enable African American Males to Become Literate Individuals--What's Going On?

    ERIC Educational Resources Information Center

    Wooten, Cynthia Brooks

    2010-01-01

    The purpose of this qualitative study was to investigate ways in which six teachers in the intermediate grades at one urban and one rural school enabled their African American male students to be successful in their literacy efforts. It was my assumption that successful teachers of African American males would also be teachers who integrated…

  20. School Memories Situating School

    ERIC Educational Resources Information Center

    Tanggaard, Lene; Nielsen, Klaus

    2013-01-01

    This paper reports the results of an interview study of 18 current and former pupils in the Danish "Folkeskole" (primary and secondary public school) from 1930 up to the present. The aim of the study is to provide a forum for usually unheard voices on the subject of everyday life in school. The study pays special attention to relational…

  1. Criegee intermediates in the indoor environment. New insights

    DOE PAGES

    Shallcross, D. E.; Taatjes, C. A.; Percival, C. J.

    2014-03-25

    Criegee intermediates are formed in the ozonolysis of alkenes and play an important role in indoor chemistry, notably as a source of OH radicals. Recent studies have shown that these Criegee intermediates react very quickly with NO2, SO2, and carbonyls, and in this study, steady-state calculations are used to inspect the potential impact of these data on indoor chemistry. It is shown that these reactions could accelerate NO3 formation and SO2 removal in the indoor environment significantly. In addition, reaction between Criegee intermediates and halogenated carbonyls could provide a significant loss process indoors, where currently one does not exist.

  2. Microbial/enzymatic synthesis of chiral pharmaceutical intermediates.

    PubMed

    Patel, Ramesh N

    2003-11-01

    Chirality is a key factor in the efficacy of many drugs; thus, the production of single enantiomers of drug intermediates has become increasingly important in the pharmaceutical industry. Chiral intermediates and fine chemicals are in high demand from the pharmaceutical and agrochemical industries for the preparation of bulk drug substances and agricultural products. There has been an increasing awareness of the enormous potential of microorganisms and enzymes for the transformation of synthetic chemicals with high chemo-, regio- and enantioselectivity. In this article, biocatalytic processes for the synthesis of chiral pharmaceutical intermediates are described.

  3. Detection of novel enzyme intermediates in PEP-utilizing enzymes.

    PubMed

    Anderson, Karen S

    2005-01-01

    This review will focus on established and newly emerging strategies for identifying and characterizing enzyme intermediates using a rapid transient kinetic approach. The merits of this methodology as well as the basics of experimental design are described. Several illustrative examples of PEP-utilizing enzymes have been chosen as they all perform unique, novel chemistries involving enzyme intermediates and have proven to be exciting pharmaceutical targets for antibiotics and herbicides. A novel application of this approach using time-resolved electrospray mass spectrometry to detect chemically labile enzyme intermediates is also discussed.

  4. Relative Risk of Violence among Department of Defense Connected Students in Hawai'i Schools: Report with Appendixes.

    ERIC Educational Resources Information Center

    Berg, Stephen R.; Berg, Kathleen F.

    This study was undertaken to determine the relative risk of violence among students attending Hawaii schools with higher proportions of children of Department of Defense (DOD) personnel. Approximately 12% of the total public school enrollment of nearly 190,000 students is DOD connected. Forty-eight schools (8 high schools, 8 intermediates, and 32…

  5. School Violence, School Differences and School Discourses

    ERIC Educational Resources Information Center

    Watkins, Chris; Mauthner, Melanie; Hewitt, Roger; Epstein, Debbie; Leonard, Diana

    2007-01-01

    This article highlights one strand of a study which investigated the concept of the violence-resilient school. In six inner-city secondary schools, data on violent incidents in school and violent crime in the neighbourhood were gathered, and compared with school practices to minimise violence, accessed through interviews. Some degree of…

  6. School Violence, School Differences and School Discourses

    ERIC Educational Resources Information Center

    Watkins, Chris; Mauthner, Melanie; Hewitt, Roger; Epstein, Debbie; Leonard, Diana

    2007-01-01

    This article highlights one strand of a study which investigated the concept of the violence-resilient school. In six inner-city secondary schools, data on violent incidents in school and violent crime in the neighbourhood were gathered, and compared with school practices to minimise violence, accessed through interviews. Some degree of…

  7. Intermediate connector for stacked organic light emitting devices

    DOEpatents

    D& #x27; Andrade, Brian

    2013-02-12

    A device is provided, having an anode, a cathode, and an intermediate connector disposed between the anode and the cathode. A first organic layer including an emissive sublayer is disposed between the anode and the intermediate connector, and a second including an emissive sublayer is disposed between the intermediate connector and the cathode. The intermediate connector includes a first metal having a work function lower than 4.0 eV and a second metal having a work function lower than 5.0 eV. The work function of the first metal is at least 0.5 eV less than the work function of the second metal. The first metal is in contact with a sublayer of the second organic layer that includes a material well adapted to receive holes from a low work function metal.

  8. The Intermediate Impossible: A Prewriting Activity for Creative Problem Solving.

    ERIC Educational Resources Information Center

    Karloff, Kenneth

    1985-01-01

    Adapts Edward de Bono's "Intermediate Impossible" strategy--for considering ideas that normally would be discarded as stepping-stones to new ideas--for use as a prewriting activity to enhance creative problem solving. (HTH)

  9. Control of nonenzymatic browning in intermediate-moisture foods

    NASA Technical Reports Server (NTRS)

    Buckle, K. A.; Labruza, T. P.; Warmbier, H. C.

    1975-01-01

    Series of compounds called humectants were found to decrease rate of browning when added to intermediate-moisture foods. Twenty percent level of humectant can increase shelf life of foods by factor of 5 or 6.

  10. 42 CFR 54a.12 - Treatment of intermediate organizations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... DISCRETIONARY FUNDING UNDER TITLE V OF THE PUBLIC HEALTH SERVICE ACT, 42 U.S.C. 290aa, ET SEQ., FOR SUBSTANCE ABUSE PREVENTION AND TREATMENT SERVICES § 54a.12 Treatment of intermediate organizations. If...

  11. 42 CFR 54a.12 - Treatment of intermediate organizations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... DISCRETIONARY FUNDING UNDER TITLE V OF THE PUBLIC HEALTH SERVICE ACT, 42 U.S.C. 290aa, ET SEQ., FOR SUBSTANCE ABUSE PREVENTION AND TREATMENT SERVICES § 54a.12 Treatment of intermediate organizations. If...

  12. 24. DETAIL VIEW OF TILE GAUGE IN INTERMEDIATE LOCK WALL, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    24. DETAIL VIEW OF TILE GAUGE IN INTERMEDIATE LOCK WALL, LOOKING NORTHEAST. NOTE STEEL WALL ARMOR EMBEDDED IN CONCRETE. - Upper Mississippi River 9-Foot Channel Project, Lock & Dam 26, Alton, Madison County, IL

  13. Functionalization of the corrole ring: the role of isocorrole intermediates.

    PubMed

    Tortora, Luca; Nardis, Sara; Fronczek, Frank R; Smith, Kevin M; Paolesse, Roberto

    2011-04-14

    Bromination of 3-nitro-5,10,15-triarylcorrole selectively provides two regioisomers, depending on the reaction pathway. An isocorrole species is the key intermediate to drive the reaction towards the 2-Br-17-nitro regioisomer.

  14. Semiannually alternating exchange of intermediate waters east of the Philippines

    NASA Astrophysics Data System (ADS)

    Song, Lina

    2017-04-01

    Intermediate water exchange in the northwest tropical Pacific is explored with the temperature, salinity, and current measurements of a mooring system deployed at 8°N, 127.05°E during 2010-2014. For the first time, prominent semiannual variability (SAV; with the maximum power at 187 days) of subthermocline meridional flow along the Mindanao coast is revealed. A significant correlation between meridional flow and salinity is found at intermediate depths. This provides direct evidence for the alternating transports of South Pacific and North Pacific Intermediate Waters by northward and southward undercurrents, respectively. Further analysis with an eddy-resolving ocean general circulation model demonstrates that the SAV is generated locally near the western boundary, manifesting as large-scale subthermocline recirculation and leading to alternating northward and southward flows near the Mindanao coast, which plays an efficient role in the intermediate water exchange of the northwest tropical Pacific. Mechanisms underlying the observed SAV are discussed

  15. 22. PIN CONNECTION AT JUNCTURE OF INTERMEDIATE VERTICAL WITH BOTTOM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    22. PIN CONNECTION AT JUNCTURE OF INTERMEDIATE VERTICAL WITH BOTTOM CHORD ON PENNSYLVANIA PETIT TRUSS. HYDRAULICALLY FORGED EYES ON ROLLED STOCK. - New River Bridge, Spanning New River at State Route 623, Pembroke, Giles County, VA

  16. 10. INTERIOR VIEW TOWARD NORTHEAST, SECOND BAY Showing intermediate doors ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. INTERIOR VIEW TOWARD NORTHEAST, SECOND BAY Showing intermediate doors cut for warehouse conversion, heating system, dormer removal repair. - U.S. Military Academy, Ice House, Mills Road at Howze Place, West Point, Orange County, NY

  17. Intermediate band solar cell with extreme broadband spectrum quantum efficiency.

    PubMed

    Datas, A; López, E; Ramiro, I; Antolín, E; Martí, A; Luque, A; Tamaki, R; Shoji, Y; Sogabe, T; Okada, Y

    2015-04-17

    We report, for the first time, about an intermediate band solar cell implemented with InAs/AlGaAs quantum dots whose photoresponse expands from 250 to ∼6000  nm. To our knowledge, this is the broadest quantum efficiency reported to date for a solar cell and demonstrates that the intermediate band solar cell is capable of producing photocurrent when illuminated with photons whose energy equals the energy of the lowest band gap. We show experimental evidence indicating that this result is in agreement with the theory of the intermediate band solar cell, according to which the generation recombination between the intermediate band and the valence band makes this photocurrent detectable.

  18. 39 CFR 3001.40 - Exceptions to intermediate decisions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... will be entertained unless the Commission, upon motion for good cause shown or on its own initiative... who fails to except or object to any part of an intermediate decision in its brief on exceptions may...

  19. 39 CFR 3001.40 - Exceptions to intermediate decisions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... will be entertained unless the Commission, upon motion for good cause shown or on its own initiative... who fails to except or object to any part of an intermediate decision in its brief on exceptions may...

  20. 39 CFR 3001.40 - Exceptions to intermediate decisions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... will be entertained unless the Commission, upon motion for good cause shown or on its own initiative... who fails to except or object to any part of an intermediate decision in its brief on exceptions may...

  1. 39 CFR 3001.40 - Exceptions to intermediate decisions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... will be entertained unless the Commission, upon motion for good cause shown or on its own initiative... who fails to except or object to any part of an intermediate decision in its brief on exceptions may...

  2. 2. GENERAL VIEW LOOKING NORTHEAST, SHOWING COKE MACHINE (CENTER), INTERMEDIATE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. GENERAL VIEW LOOKING NORTHEAST, SHOWING COKE MACHINE (CENTER), INTERMEDIATE TIPPLE (RIGHT), AND OVENS - Shoaf Mine & Coke Works, East side of Shoaf, off Township Route 472, Shoaf, Fayette County, PA

  3. Proteomics characterization of intermediate wheatgrass (Thinopyrum intermedium) flour proteins

    USDA-ARS?s Scientific Manuscript database

    Thinopyrum intermedium, commonly known as intermediate wheatgrass (IWG), is a perennial crop with favorable agronomic characteristics and nutritional benefits. IWG lines are deficient in high molecular weight glutenins (HMWG), responsible for dough strength. A detailed characterization of IWG flou...

  4. Radiation treatment for patients with intermediate-risk prostate cancer

    PubMed Central

    Mayadev, Jyoti S.; Valicenti, Richard K.

    2012-01-01

    Around 70% of men presenting with prostate cancer will have organ-confined disease, with the majority presenting with low- or intermediate-risk prostate cancer. This article reviews the evidence supporting the current standard of care in radiation oncology for the evaluation and management of men with intermediate-risk prostate cancer. Dose escalation, hormonal therapy, combined modality therapy, and modern techniques for the delivery of radiation therapy are reviewed. PMID:22654963

  5. Remission of Intermediate Uveitis: Incidence and Predictive Factors.

    PubMed

    Kempen, John H; Gewaily, Dina Y; Newcomb, Craig W; Liesegang, Teresa L; Kaçmaz, R Oktay; Levy-Clarke, Grace A; Nussenblatt, Robert B; Rosenbaum, James T; Sen, H Nida; Suhler, Eric B; Thorne, Jennifer E; Foster, C Stephen; Jabs, Douglas A; Payal, Abhishek; Fitzgerald, Tonetta D

    2016-04-01

    To evaluate the incidence of remission among patients with intermediate uveitis; to identify factors potentially predictive of remission. Retrospective cohort study. Involved eyes of patients with primary noninfectious intermediate uveitis at 4 academic ocular inflammation subspecialty practices, followed sufficiently long to meet the remission outcome definition, were studied retrospectively by standardized chart review data. Remission of intermediate uveitis was defined as a lack of inflammatory activity at ≥2 visits spanning ≥90 days in the absence of any corticosteroid or immunosuppressant medications. Factors potentially predictive of intermediate uveitis remission were evaluated using survival analysis. Among 849 eyes (of 510 patients) with intermediate uveitis followed over 1934 eye-years, the incidence of intermediate uveitis remission was 8.6/100 eye-years (95% confidence interval [CI], 7.4-10.1). Factors predictive of disease remission included prior pars plana vitrectomy (PPV) (hazard ratio [HR] [vs no PPV] = 2.39; 95% CI, 1.42-4.00), diagnosis of intermediate uveitis within the last year (HR [vs diagnosis >5 years ago] =3.82; 95% CI, 1.91-7.63), age ≥45 years (HR [vs age <45 years] = 1.79; 95% CI, 1.03-3.11), female sex (HR = 1.61; 95% CI, 1.04-2.49), and Hispanic race/ethnicity (HR [vs white race] = 2.81; 95% CI, 1.23-6.41). Presence/absence of a systemic inflammatory disease, laterality of uveitis, and smoking status were not associated with differential incidence. Our results suggest that intermediate uveitis is a chronic disease with an overall low rate of remission. Recently diagnosed patients and older, female, and Hispanic patients were more likely to remit. With regard to management, pars plana vitrectomy was associated with increased probability of remission. Copyright © 2016 Elsevier Inc. All rights reserved.

  6. Side Group Construction in High Polymeric Phosphazenes via Lithiophenoxy Intermediates.

    DTIC Science & Technology

    1980-09-22

    the lithio- C:0 derivatives of aryloxyphosphazene high polymers . These were used as C..3 intermediates for the introduction of phosphine-, organotin ...Department of Chemistry, The Pennsylvania State University University Park, Pennsylvania 16802 ABSTRACT The new lithiophenoxyphosphazene high polymers , [NP...2 ]n or [NP (OC6H4Br-i)x- (OPh) y n at -400C to -60*C. The lithio-derivatives were used as reactive intermediates for the synthesis of polymers of

  7. Membrane potential stabilizes the O intermediate in liposomes containing bacteriorhodopsin.

    PubMed

    Kalaidzidis, I V; Belevich, I N; Kalaidzidis, Y L; Kaulen, A D

    1999-10-01

    In the bacteriorhodopsin-containing proteoliposomes, a laser flash is found to induce formation of a bathointermediate decaying in several seconds, the difference spectrum being similar to the purple-blue transition. Different pH buffers do not affect the intermediate, whereas an uncoupler, gramicidin A, and lipophilic ions accelerate decay of the intermediate or inhibit its formation. In the liposomes containing E204Q bacteriorhodopsin mutant, formation of the intermediate is suppressed. In the wild-type bacteriorhodopsin liposomes, the bathointermediate formation is pH-independent within the pH 5-7 range. The efficiency of the long-lived O intermediate formation increases at a low pH. In the wild-type as well as in the E204Q mutant purple membrane, the O intermediate decay is slowed down at slightly higher pH values than that of the purple-blue transition. It is suggested that the membrane potential affects the equilibrium between the bacteriorhodopsin ground state (Glu-204 is protonated and Asp-85 is deprotonated) and the O intermediate (Asp-85 is protonated and Glu-204 is deprotonated), stabilizing the latter by changing the relative affinity of Asp-85 and Glu-204 to H(+). At a low pH, protonation of a proton-releasing group (possibly Glu-194) in the bacteriorhodopsin ground state seems to prevent deprotonation of the Glu-204 during the photocycle. Thus, all protonatable residues of the outward proton pathway should be protonated in the O intermediate. Under such conditions, membrane potential stabilization of the O intermediate in the liposomes can be attributed to the direct effect of the potential on the pK value of Asp-85.

  8. Oxygen-hydrogen sulfide intermediate layer of the Black Sea

    SciTech Connect

    Timoshchuk, V.I.; Risik, N.S.

    1980-01-01

    Spatial and vertical boundaries were studied for the oxygen-hydrogen sulfide intermediate layer in the Black Sea. The wind has a great influence on the thermohaline structure of the Danube coastal waters. It causes strong out-and-influx processes and up-welling of hydrogen sulfide waters of the intermediate layer in the north-western part of the Black Sea, which is supposed to be one of the reasons for the ecological equilibrium disturbance in this region.

  9. School Improvement through Government Agencies: Loose or Tight Coupling?

    ERIC Educational Resources Information Center

    Bush, Tony

    2017-01-01

    In seeking to improve student outcomes, governments may choose to exercise direct control over schools, as in many centralised systems, or to provide frameworks for intermediate bodies to engage in improvement activities. One such body is the National College for School Leadership (NCSL), now the National College for Teaching and Leadership (NCTL)…

  10. Principals' Perceptions of the School Counsellor Role in Saudi Arabia

    ERIC Educational Resources Information Center

    Alghamdi, Nawal G.; Riddick, Barbara

    2011-01-01

    Many factors in Saudi society have led to a need for counselling services in educational institutions. However, concerns remain that the role of school counsellors in that setting is unclear. An aim of this study was to determine the perceptions of principals concerning the actual and ideal role of intermediate girls school counsellors in Saudi…

  11. Smoking and Health Guide for Elementary and Secondary Schools.

    ERIC Educational Resources Information Center

    Washington Office of the State Superintendent of Public Instruction, Olympia.

    GRADES OR AGES: Grades 4-12. SUBJECT MATTER: Smoking. ORGANIZATION AND PHYSICAL APPEARANCE: The guide is divided into three sections, one each for intermediate grades, junior high school, and senior high school. Each section is further divided into units organized around "conceptual statements." Units are laid out in four columns across two pages.…

  12. Perspectives of Disciplinary Problems and Practices in Elementary Schools

    ERIC Educational Resources Information Center

    Huger Marsh, Darlene P.

    2012-01-01

    Ill-discipline in public schools predates compulsory education in the United States. Disciplinary policies and laws enacted to combat the problem have met with minimal success. Research and recommendations have generally focused on the indiscipline problems ubiquitous in intermediate, junior and senior high schools. However, similar misbehaviors…

  13. The Efficiency of Public Schools: The Case of Kuwait

    ERIC Educational Resources Information Center

    Burney, Nadeem A.; Johnes, Jill; Al-Enezi, Mohammed; Al-Musallam, Marwa

    2013-01-01

    This paper investigates the technical, and allocative efficiencies of public schools in Kuwait over four levels of schooling (kindergartens, primary, intermediate and secondary) and two periods (1999/2000 and 2004/2005) using data envelopment analysis. Mean pure technical efficiency varies between 0.695 and 0.852 across all levels of education;…

  14. The Efficiency of Public Schools: The Case of Kuwait

    ERIC Educational Resources Information Center

    Burney, Nadeem A.; Johnes, Jill; Al-Enezi, Mohammed; Al-Musallam, Marwa

    2013-01-01

    This paper investigates the technical, and allocative efficiencies of public schools in Kuwait over four levels of schooling (kindergartens, primary, intermediate and secondary) and two periods (1999/2000 and 2004/2005) using data envelopment analysis. Mean pure technical efficiency varies between 0.695 and 0.852 across all levels of education;…

  15. PAH Intermediates: Links between the Atmosphere and Biological Systems

    PubMed Central

    SIMONICH, STACI L. MASSEY; MOTORYKIN, OLEKSII; JARIYASOPIT, NARUMOL

    2010-01-01

    China is now the world's largest emitter of polycyclic aromatic hydrocarbons (PAHs). In addition, PAHs, and their reactive intermediates, undergo trans-Pacific atmospheric transport to the Western U.S. The objectives of our research are to predict, identify and quantify novel PAH intermediates in the atmosphere and biological systems, using computational methods, as well as laboratory and field experiments. Gaussian is used to predict the thermodynamic properties of parent structure PAHs, as well as the associated nitro-, oxy-, and hydroxy- PAH intermediates. Based on these predictions, state-of-the-art analytical chemistry techniques are used to identify and quantify these potential intermediates on Asian particulate matter before and after reaction in a continuous flow photochemical reactor. These same techniques are used to identify the relative proportion of PAH intermediates in PAH source regions (such as Beijing, China) and during long-range atmospheric transport to the Western U.S. PAH personal exposure studies in China and the Confederated Tribes of the Umatilla Indian Reservation in Oregon will be used to assess the similarities and differences in the PAH intermediates in biological systems relative to the atmosphere. PMID:20849837

  16. Non-Heme Fe(IV)-Oxo Intermediates

    PubMed Central

    Krebs, Carsten; Galonić-Fujimori, Danica P.; Walsh, Christopher T.; Bollinger, J. Martin

    2012-01-01

    High-valent non-heme iron-oxo intermediates have been proposed for decades as the key intermediates in numerous biological oxidation reactions. In the last three years, the first direct characterization of such intermediates has been provided by studies of several αKG-dependent oxygenases that catalyze either hydroxylation or halogenation of their substrates. In each case, the Fe(IV)-oxo intermediate is implicated in cleavage of the aliphatic C-H bond to initiate hydroxylation or halogenation. The observation of non-heme Fe(IV)-oxo intermediates and Fe(II)-containing product(s) complexes with almost identical spectroscopic parameters in the reactions of two distantly related αKG-dependent hydroxylases suggests that members of this sub-family follow a conserved mechanism for substrate hydroxylation. In contrast, for the αKG-dependent non-heme-iron halogenase, CytC3, two distinct Fe(IV) complexes form and decay together, suggesting that they are in rapid equilibrium. The existence of two distinct conformers of the Fe site may be the key factor accounting for the divergence of the halogenase reaction from the more usual hydroxylation pathway after C-H cleavage. Distinct transformations catalyzed by other mononuclear non-heme enzymes are likely also to involve initial C-H-cleavage by Fe(IV)-oxo complexes, followed by diverging reactivities of the resulting Fe(III)-hydroxo/substrate radical intermediates. PMID:17542550

  17. School Climate.

    ERIC Educational Resources Information Center

    Lindelow, John; Mazzarella, Jo Ann

    Chapter 7 of a volume on school leadership, this chapter defines, describes, and suggests ways to improve climate at the school building level. After citing a number of definitions of school climate, the authors conclude that school climate is the feel an individual gets from experiences within a school system, or the global summation of the…

  18. School Climate.

    ERIC Educational Resources Information Center

    Lindelow, John; And Others

    Chapter 8 of a revised volume on school leadership, this chapter defines school climate and suggests ways to improve the learning environment at the school building level. School climate is defined as the feeling an individual gets from experiences within a school system. More specifically, climate is the composite of norms, expectations, and…

  19. School Law.

    ERIC Educational Resources Information Center

    Splitt, David A.

    1983-01-01

    Discusses recent court cases in the states of Washington and Pennsylvania that mandate equal pay for equal work for school personnel and offers suggestions to school administrators for dealing with requests for censorship in public schools. (JBM)

  20. Students' Coping with Academic and Social Stress in an Inner-City Middle School.

    ERIC Educational Resources Information Center

    Fahs, Mary Ellen

    This report presents the findings of several studies designed to examine students' coping processes in relation to stressful academic and social situations in the school environment. The setting for these studies was an inner-city intermediate school with approximately 423 students in the 1984-85 school year. Over 95 percent of the students were…

  1. Perspective: Spectroscopy and kinetics of small gaseous Criegee intermediates

    SciTech Connect

    Lee, Yuan-Pern

    2015-07-14

    The Criegee intermediates, carbonyl oxides proposed by Criegee in 1949 as key intermediates in the ozonolysis of alkenes, play important roles in many aspects of atmospheric chemistry. Because direct detection of these gaseous intermediates was unavailable until recently, previous understanding of their reactions, derived from indirect experimental evidence, had great uncertainties. Recent laboratory detection of the simplest Criegee intermediate CH{sub 2}OO and some larger members, produced from ultraviolet irradiation of corresponding diiodoalkanes in O{sub 2}, with various methods such as photoionization, ultraviolet absorption, infrared absorption, and microwave spectroscopy opens a new door to improved understanding of the roles of these Criegee intermediates. Their structures and spectral parameters have been characterized; their significant zwitterionic nature is hence confirmed. CH{sub 2}OO, along with other products, has also been detected directly with microwave spectroscopy in gaseous ozonolysis reactions of ethene. The detailed kinetics of the source reaction, CH{sub 2}I + O{sub 2}, which is critical to laboratory studies of CH{sub 2}OO, are now understood satisfactorily. The kinetic investigations using direct detection identified some important atmospheric reactions, including reactions with NO{sub 2}, SO{sub 2}, water dimer, carboxylic acids, and carbonyl compounds. Efforts toward the characterization of larger Criegee intermediates and the investigation of related reactions are in progress. Some reactions of CH{sub 3}CHOO are found to depend on conformation. This perspective examines progress toward the direct spectral characterization of Criegee intermediates and investigations of the associated reaction kinetics, and indicates some unresolved problems and prospective challenges for this exciting field of research.

  2. MicroRNA profiling of human intermediate monocytes.

    PubMed

    Zawada, Adam M; Zhang, Lu; Emrich, Insa E; Rogacev, Kyrill S; Krezdorn, Nicolas; Rotter, Björn; Fliser, Danilo; Devaux, Yvan; Ziegler-Heitbrock, Loems; Heine, Gunnar H

    2017-03-01

    Among the three human monocyte subsets, intermediate CD14++CD16+ monocytes have been characterized as particularly proinflammatory cells in experimental studies and as potential biomarkers of cardiovascular risk in clinical cohorts. To further substantiate the distinct role of intermediate monocytes within human monocyte heterogeneity, we assessed subset-specific expression of miRNAs as central epigenetic regulators of gene expression. We hypothesized that intermediate monocytes have a distinct miRNA profile compared to classical and non-classical monocytes. By using small RNA-seq we analyzed 662 miRNAs in the three monocyte subsets. We identified 38 miRNAs that are differentially expressed in intermediate monocytes compared to both classical and non-classical monocytes with a p value of <10(-10), of which two miRNAs - miR-6087 (upregulated) and miR-150-5p (downregulated) - differed in their expression more than ten-fold. Pathway analysis of the 38 differentially expressed miRNAs linked intermediate monocytes to distinct biological processes such as gene regulation, cell differentiation, toll-like receptor signaling as well as antigen processing and presentation. Moreover, differentially expressed miRNAs were connected to those genes that we previously identified as markers of intermediate monocytes. In aggregation, we provide first genome-wide miRNA data in the context of monocyte heterogeneity, which substantiate the concept of monocyte trichotomy in human immunity. The identification of miRNAs that are specific for intermediate monocytes may allow to develop strategies, which particularly target this cell population while sparing the other two subsets.

  3. Thermodynamic characterization of an equilibrium folding intermediate of staphylococcal nuclease.

    PubMed Central

    Xie, D.; Fox, R.; Freire, E.

    1994-01-01

    High-sensitivity differential scanning calorimetry and CD spectroscopy have been used to probe the structural stability and measure the folding/unfolding thermodynamics of a Pro117-->Gly variant of staphylococcal nuclease. It is shown that at neutral pH the thermal denaturation of this protein is well accounted for by a 2-state mechanism and that the thermally denatured state is a fully hydrated unfolded polypeptide. At pH 3.5, thermal denaturation results in a compact denatured state in which most, if not all, of the helical structure is missing and the beta subdomain apparently remains largely intact. At pH 3.0, no thermal transition is observed and the molecule exists in the compact denatured state within the 0-100 degrees C temperature interval. At high salt concentration and pH 3.5, the thermal unfolding transition exhibits 2 cooperative peaks in the heat capacity function, the first one corresponding to the transition from the native to the intermediate state and the second one to the transition from the intermediate to the unfolded state. As is the case with other proteins, the enthalpy of the intermediate is higher than that of the unfolded state at low temperatures, indicating that, under those conditions, its stabilization must be of an entropic origin. The folding intermediate has been modeled by structural thermodynamic calculations. Structure-based thermodynamic calculations also predict that the most probable intermediate is one in which the beta subdomain is essentially intact and the rest of the molecule unfolded, in agreement with the experimental data. The structural features of the equilibrium intermediate are similar to those of a kinetic intermediate previously characterized by hydrogen exchange and NMR spectroscopy. PMID:7756977

  4. Childhood Obesity: A School-Based Program.

    ERIC Educational Resources Information Center

    Strauss, Charlotte

    This model of an eight-week childhood obesity program for intermediate elementary through junior high school students addresses the social, psychological, and physical penalties often incurred by obese children. The materials detail the program format in terms of: (1) a daily food log; (2) a discussion of proper nutrition; (3) a contract for…

  5. Childhood Obesity: A School-Based Program.

    ERIC Educational Resources Information Center

    Strauss, Charlotte

    This model of an eight-week childhood obesity program for intermediate elementary through junior high school students addresses the social, psychological, and physical penalties often incurred by obese children. The materials detail the program format in terms of: (1) a daily food log; (2) a discussion of proper nutrition; (3) a contract for…

  6. Why Are C3-C4 Intermediate Species Rare?

    NASA Astrophysics Data System (ADS)

    Johnson, J. E.; Field, C. B.; Berry, J. A.

    2014-12-01

    While C3-C4 intermediate photosynthesis is thought to represent the evolutionary bridge between C3 and C4 photosynthesis, C3-C4 intermediate species are ecologically rare in comparison to both C3 and C4 species. Here, we report results from a laboratory experiment, field observations, and model simulations that suggest a new explanation for the ecological rarity of C3-C4 intermediate species. In the laboratory experiment, we combined gas exchange and fluorescence to characterize the temperature response of photosynthesis in three closely-related species in the genus Flaveria that are representatives of the C3, C3-C4 intermediate, and C4 photosynthetic pathways. The leaf temperature that maximized the quantum yield for CO2 assimilation (Topt(ΦCO2)) was 24.9 ± 0.7°C in Flaveria robusta (C3), 29.8 ± 1.0°C in F. chloraefolia (C3-C4), and 35.7 ± 0.8°C in F. bidentis (C4), and was linearly related to the temperature sensitivity of the coupling between CO2 assimilation and electron transport (d(ΦCO2/ ΦPSII)/dT)). While F. chloraefolia does not simultaneously occur with F. robusta and F. bidentis in naturally-assembled communities, this C3-C4 intermediate species does occur with other C3 and C4 species. During the growing season in two of these mixed-photosynthetic-type communities, leaf temperatures for F. chloraefolia were similar to the Topt(ΦCO2) determined in the laboratory. A model of maximum potential carbon gain suggests that competitive coexistence of C3, C3-C4 intermediate, and C4 species could be dependent on a temperature regime that highlights the distinct relative advantages of the C3-C4 intermediate pathway. In combination, these results suggest that the relative temperature sensitivity of the C3, C3-C4 intermediate, and C4 photosynthetic pathways combined with environmental variation in temperature may help to explain why C3-C4 intermediate species are generally rare.

  7. Intermediate Filaments at the Junction of Mechanotransduction, Migration, and Development

    PubMed Central

    Sanghvi-Shah, Rucha; Weber, Gregory F.

    2017-01-01

    Mechanically induced signal transduction has an essential role in development. Cells actively transduce and respond to mechanical signals and their internal architecture must manage the associated forces while also being dynamically responsive. With unique assembly-disassembly dynamics and physical properties, cytoplasmic intermediate filaments play an important role in regulating cell shape and mechanical integrity. While this function has been recognized and appreciated for more than 30 years, continually emerging data also demonstrate important roles of intermediate filaments in cell signal transduction. In this review, with a particular focus on keratins and vimentin, the relationship between the physical state of intermediate filaments and their role in mechanotransduction signaling is illustrated through a survey of current literature. Association with adhesion receptors such as cadherins and integrins provides a critical interface through which intermediate filaments are exposed to forces from a cell's environment. As a consequence, these cytoskeletal networks are posttranslationally modified, remodeled and reorganized with direct impacts on local signal transduction events and cell migratory behaviors important to development. We propose that intermediate filaments provide an opportune platform for cells to both cope with mechanical forces and modulate signal transduction. PMID:28959689

  8. Intermediate Filaments at the Junction of Mechanotransduction, Migration, and Development.

    PubMed

    Sanghvi-Shah, Rucha; Weber, Gregory F

    2017-01-01

    Mechanically induced signal transduction has an essential role in development. Cells actively transduce and respond to mechanical signals and their internal architecture must manage the associated forces while also being dynamically responsive. With unique assembly-disassembly dynamics and physical properties, cytoplasmic intermediate filaments play an important role in regulating cell shape and mechanical integrity. While this function has been recognized and appreciated for more than 30 years, continually emerging data also demonstrate important roles of intermediate filaments in cell signal transduction. In this review, with a particular focus on keratins and vimentin, the relationship between the physical state of intermediate filaments and their role in mechanotransduction signaling is illustrated through a survey of current literature. Association with adhesion receptors such as cadherins and integrins provides a critical interface through which intermediate filaments are exposed to forces from a cell's environment. As a consequence, these cytoskeletal networks are posttranslationally modified, remodeled and reorganized with direct impacts on local signal transduction events and cell migratory behaviors important to development. We propose that intermediate filaments provide an opportune platform for cells to both cope with mechanical forces and modulate signal transduction.

  9. Mechanisms of deterioration of intermediate moisture food systems

    NASA Technical Reports Server (NTRS)

    Labuza, T. P.

    1972-01-01

    A study of shelf stability in intermediate moisture foods was made. Major efforts were made to control lipid oxidation and nonenzymatic browning. In order to determine means of preventing these reactions, model systems were developed having the same water activity content relationship of intermediate moisture foods. Models were based on a cellulose-lipid and protein-lipid system with glycerol added as the humectant. Experiments with both systems indicate that lipid oxidation is promoted significantly in the intermediate moisture range. The effect appeared to be related to increased mobility of either reactants or catalysts, since when the amount of water in the system reached a level where capillary condensation occurred and thus free water was present, the rates of oxidation increased. With added glycerol, which is water soluble and thus increases the amount of mobile phase, the increase in oxidation rate occurs at a lower relative humidity. The rates of oxidation were maximized at 61% RH and decreased again at 75% RH probably due to dilution. No significant non-enzymatic browning occurred in the protein-lipid systems. Prevention of oxidation by the use of metal chelating agents was enhanced in the cellulose system, whereas, with protein present, the lipid soluble chain terminating antioxidants (such as BHA) worked equally as well. Preliminary studies of foods adjusted to the intermediate moisture range bear out the results of oxidation in model systems. It can be concluded that for most fat containing intermediate moisture foods, rancidity will be the reaction most limiting stability.

  10. Membrane fusion machines of paramyxoviruses: capture of intermediates of fusion

    PubMed Central

    Russell, Charles J.; Jardetzky, Theodore S.; Lamb, Robert A.

    2001-01-01

    Peptides derived from heptad repeat regions adjacent to the fusion peptide and transmembrane domains of many viral fusion proteins form stable helical bundles and inhibit fusion specifically. Paramyxovirus SV5 fusion (F) protein-mediated fusion and its inhibition by the peptides N-1 and C-1 were analyzed. The temperature dependence of fusion by F suggests that thermal energy, destabilizing proline residues and receptor binding by the hemagglutinin–neuraminidase (HN) protein collectively contribute to F activation from a metastable native state. F-mediated fusion was reversibly arrested by low temperature or membrane-incorporated lipids, and the resulting F intermediates were characterized. N-1 inhibited an earlier F intermediate than C-1. Co-expression of HN with F lowered the temperature required to attain the N-1-inhibited intermediate, consistent with HN binding to its receptor stimulating a conformational change in F. C-1 bound and inhibited an intermediate of F that could be detected until a point directly preceding membrane merger. The data are consistent with C-1 binding a pre-hairpin intermediate of F and with helical bundle formation being coupled directly to membrane fusion. PMID:11483506

  11. Kinetics, mechanisms and products of reactions of Criegee intermediates

    NASA Astrophysics Data System (ADS)

    Orr-Ewing, Andrew

    The atmospheric ozonolysis of alkenes such as isoprene produces Criegee intermediates which are increasingly recognized as important contributors to oxidation chemistry in the Earth's troposphere. Stabilized Criegee intermediates are conveniently produced in the laboratory by ultraviolet photolysis of diiodoalkanes in the presence of O2, and can be detected by absorption spectroscopy using their strong electronic bands in the near ultraviolet region. We have used these techniques to study a wide range of reactions of Criegee intermediates, including their self-reactions, and reactions with carboxylic acids and various other trace atmospheric constituents. In collaboration with the Sandia National Laboratory group led by Drs C.A. Taatjes and D.L. Osborn, we have used photoionization and mass spectrometry methods, combined with electronic structure calculations, to characterize the products of several of these reactions. Our laboratory studies determine rate coefficients for the Criegee intermediate reactions, many of which prove to be fast. In the case of reactions with carboxylic acids, a correlation between the dipole moments of the reactants and the reaction rate coefficients suggests a dipole-capture controlled reaction and allows us to propose a structure-activity relationship to predict the rates of related processes. The contributions of these various Criegee intermediate reactions to the chemistry of the troposphere have been assessed using the STOCHEM-CRI global atmospheric chemistry model. This work was supported by NERC grant NE/K004905/1.

  12. Hydroxyacetone production from C3 Criegee intermediates

    SciTech Connect

    Taatjes, Craig A.; Liu, Fang; Rotavera, Brandon; Kumar, Manoj; Caravan, Rebecca; Osborn, David L.; Thompson, Ward H.; Lester, Marsha I.

    2016-12-21

    Hydroxyacetone (CH3C(O)CH2OH) is observed as a stable end product from reactions of the (CH3)2COO Criegee intermediate, acetone oxide, in a flow tube coupled with multiplexed photoionization mass spectrometer detection. In the experiment, the isomers at m/z = 74 are distinguished by their different photoionization spectra and reaction times. Hydroxyacetone is observed as a persistent signal at longer reaction times at a higher photoionization threshold of ca. 9.7 eV than Criegee intermediate and definitively identified by comparison with the known photoionization spectrum. Complementary electronic structure calculations reveal multiple possible reaction pathways for hydroxyacetone formation, including unimolecular isomerization via hydrogen atom transfer and –OH group migration as well as self-reaction of Criegee intermediates. Varying the concentration of Criegee intermediates suggests contributions from both unimolecular and self-reaction pathways to hydroxyacetone. As a result, the hydroxyacetone end product can provide an effective, stable marker for the production of transient Criegee intermediates in future studies of alkene ozonolysis.

  13. Tasman Leakage of intermediate waters as inferred from Argo floats

    NASA Astrophysics Data System (ADS)

    Rosell-Fieschi, Miquel; Rintoul, Stephen R.; Gourrion, Jeröme; Pelegrí, Josep L.

    2013-10-01

    use Argo float trajectories to infer ocean current velocity at the sea surface and 1000 dbar near Australia. The East Australian Current flows southward along the east coast of Australia at both surface and intermediate levels, but only the intermediate waters leak round the southern tip of Tasmania and cross the Great Australian Bight. We calculate the transport of Antarctic Intermediate Water (AAIW) between the southern Australian coast and the Antarctic Circumpolar Current (ACC) as the velocity at 1000 dbar times the layer thickness. Between March 2006 and December 2012, the Eulerian AAIW transport through 147°E ranges between 0 and 12.0 sverdrup (Sv). The mean Tasman Leakage of intermediate waters from the Pacific Ocean into the Indian Ocean, obtained using all Argo data until March 2013, is 3.8 ± 1.3 Sv. The mean intermediate water transport into the Indian Ocean through 115°E increases to 5.2 ± 1.8 Sv due to contributions from the westward recirculation of ACC waters.

  14. Determination of the dissociation kinetics of a transient intermediate.

    PubMed

    Asam, M R; Glish, G L

    1999-02-01

    Tandem mass spectrometry provides information on the dissociation pathways of gas-phase ions by providing a link between product ions and parent ions. However, there exists a distinct possibility that a parent ion does not dissociate directly to the observed product ion, but that the reaction proceeds through unobserved reaction intermediates. This work describes the discovery and kinetic analysis of an unobserved reaction intermediate with a quadrupole ion trap. [a4 - NH3] ions formed from [YG beta FL + H] ions dissociate to [(F*YG - NH3) - CO] ions. It is expected, however, from previous results, that [F*YG - NH3] ions should form prior to [(F*YG - NH3) - CO] ions. Double-resonance experiments are used to demonstrate the existence of intermediate [F*YG - NH3] ions. Various kinetic analyses are then performed using traditional collision-induced dissociation kinetics and double-resonance experiments. The phenomenological rates of formation and decay of peptide rearrangement ion dissociation products are determined by curve fitting decay and formation data generated with the kinetics experiments. The data generated predict an observable level of the intermediate in a time frame accessible but previously not monitored. By examining early product-ion formation, the intermediate ions, [F*YG - NH3]+, are observed.

  15. What causes hyperfluorescence: folding intermediates or conformationally flexible native states?

    PubMed Central

    Ervin, John; Larios, Edgar; Osváth, Szabolcs; Schulten, Klaus; Gruebele, Martin

    2002-01-01

    Hyperfluorescent intensity maxima during protein unfolding titrations are often taken as a sign for a thermodynamic folding intermediate. Here we explore another possibility: that hyperfluorescence could be the signature of a "pretransition" conformationally loosened native state. To model such native states, we study mutants of a fluorescent ubiquitin variant, placing cavities at various distances from the tryptophan fluorophore. We examine the correlation between protein flexibility and enhanced fluorescence intensity by using circular dichroism, fluorescence intensity unfolding titrations, fluorescence anisotropy measurements, and molecular dynamics. Based on experiment and simulation, we propose a simple model for hyperfluorescence in terms of static and dynamic conformational properties of the native state during unfolding. Apomyoglobin denaturant unfolding and phosphoglycerate kinase cold denaturation are discussed as examples. Our results do not preclude the existence of thermodynamic intermediates but do raise caution that by itself, hyperfluorescence during unfolding titrations is not conclusive proof of thermodynamic folding intermediates. PMID:12080134

  16. Transiting Sub-stellar companions of Intermediate-mass stars

    NASA Astrophysics Data System (ADS)

    Sebastian, Daniel; Guenther, Eike W.; Heber, Ulrich; Geier, Stephan; Grziwa, Sascha

    2015-09-01

    We use the CoRoT-survey to search for transiting close-in planets of intermediate-mass stars (M* = 1.3 - 2.1 M⊙). We present recent results of our survey. RV-surveys and direct imaging campaigns showed, that intermediate-mass main-sequence stars have more massive planets then solar-like stars. Even brown dwarfs have been found. In our study we concentrated on short-period planets for which a mass-determination is possible. The detection of close-in planets of intermediate-mass stars put strong constraints on the timescales of the formation and migration. We already have identified transiting Jupiter-like planet candidates with short orbital periods and observed these candidates with high-resolution echelle-spectrographs at various Telescopes.

  17. Accomplishing structural change: identifying intermediate indicators of success.

    PubMed

    Miller, Robin Lin; Reed, Sarah J; Francisco, Vincent

    2013-03-01

    Coalitions are routinely employed across the United States as a method of mobilizing communities to improve local conditions that impact on citizens' well-being. Success in achieving specific objectives for environmental or structural community change may not quickly translate into improved population outcomes in the community, posing a dilemma for coalitions that pursue changes that focus on altering community conditions. Considerable effort by communities to plan for and pursue structural change objectives, without evidence of logical and appropriate intermediate markers of success could lead to wasted effort. Yet, the current literature provides little guidance on how coalitions might select intermediate indicators of achievement to judge their progress and the utility of their effort. The current paper explores the strengths and weaknesses of various indicators of intermediate success in creating structural changes among a sample of 13 coalitions organized to prevent exposure to HIV among high-risk adolescents in their local communities.

  18. Hybrid songbirds employ intermediate routes in a migratory divide.

    PubMed

    Delmore, Kira E; Irwin, Darren E

    2014-10-01

    Migratory divides are contact zones between populations that use different routes to navigate around unsuitable areas on seasonal migration. Hybrids in divides have been predicted to employ intermediate and potentially inferior routes. We provide the first direct test of this hypothesis, using light-level geolocators to track birds breeding in a hybrid zone between Swainson's thrushes in western Canada. Compared to parental forms, hybrids exhibited increased variability in their migratory routes, with some using intermediate routes that crossed arid and mountainous regions, and some using the same routes as one parental group on fall migration and the other on spring migration. Hybrids also tended to use geographically intermediate wintering sites. Analysis of genetic variation across the hybrid zone suggests moderately strong selection against hybrids. These results indicate that seasonal migratory behaviour might be a source of selection against hybrids, supporting a possible role for migration in speciation.

  19. AmeriFlux US-Wi1 Intermediate hardwood (IHW)

    SciTech Connect

    Chen, Jiquan

    2016-01-01

    This is the AmeriFlux version of the carbon flux data for the site US-Wi1 Intermediate hardwood (IHW). Site Description - The Wisconsin Intermediate Hardwoods site is located in the Washburn Ranger District of the Chequamegon National Forest. A member of the northern coniferous-deciduous biome, surveys from the mid-19th century indicate the region consisted of a mixed stand of red, white, and jack pines. After extensive timber harvesting, wildfires, and farming activity, the region turned into a fragmented mosaic of stands of various ages and composition. The intermediate hardwoods site is one of ten sites that collectively represent the successional stages of development in the predominant stand types of a physically homogeneous landscape. In 2001, northern hardwood stands of all ages occupied 45% of the region.

  20. Replicative intermediates of maize streak virus found during leaf development.

    PubMed

    Erdmann, Julia B; Shepherd, Dionne N; Martin, Darren P; Varsani, Arvind; Rybicki, Edward P; Jeske, Holger

    2010-04-01

    Geminiviruses of the genera Begomovirus and Curtovirus utilize three replication modes: complementary-strand replication (CSR), rolling-circle replication (RCR) and recombination-dependent replication (RDR). Using two-dimensional gel electrophoresis, we now show for the first time that maize streak virus (MSV), the type member of the most divergent geminivirus genus, Mastrevirus, does the same. Although mastreviruses have fewer regulatory genes than other geminiviruses and uniquely express their replication-associated protein (Rep) from a spliced transcript, the replicative intermediates of CSR, RCR and RDR could be detected unequivocally within infected maize tissues. All replicative intermediates accumulated early and, to varying degrees, were already present in the shoot apex and leaves at different maturation stages. Relative to other replicative intermediates, those associated with RCR increased in prevalence during leaf maturation. Interestingly, in addition to RCR-associated DNA forms seen in other geminiviruses, MSV also apparently uses dimeric open circular DNA as a template for RCR.