Characterization of robotics parallel algorithms and mapping onto a reconfigurable SIMD machine

NASA Technical Reports Server (NTRS)

Lee, C. S. G.; Lin, C. T.

1989-01-01

The kinematics, dynamics, Jacobian, and their corresponding inverse computations are six essential problems in the control of robot manipulators. Efficient parallel algorithms for these computations are discussed and analyzed. Their characteristics are identified and a scheme on the mapping of these algorithms to a reconfigurable parallel architecture is presented. Based on the characteristics including type of parallelism, degree of parallelism, uniformity of the operations, fundamental operations, data dependencies, and communication requirement, it is shown that most of the algorithms for robotic computations possess highly regular properties and some common structures, especially the linear recursive structure. Moreover, they are well-suited to be implemented on a single-instruction-stream multiple-data-stream (SIMD) computer with reconfigurable interconnection network. The model of a reconfigurable dual network SIMD machine with internal direct feedback is introduced. A systematic procedure internal direct feedback is introduced. A systematic procedure to map these computations to the proposed machine is presented. A new scheduling problem for SIMD machines is investigated and a heuristic algorithm, called neighborhood scheduling, that reorders the processing sequence of subtasks to reduce the communication time is described. Mapping results of a benchmark algorithm are illustrated and discussed.

The Best of Two Worlds: ALMA + IRAM30M Observations of the Orion Integral Shape Filament

NASA Astrophysics Data System (ADS)

Hacar Gonzalez, Alvaro

2018-01-01

We have investigated the internal gas structure of the Orion Integral Shape filament using two large-scale, 150-pointing ALMA-12m mosaics and previous IRAM30m single-dish (SD) observations. From the combination of both single-dish and interferometric data we have produced a high-dynamic range and high-sensitivity map describing the internal gas structure of this filament at scales between 2 pc and 2000 AU (Hacar et al, submitted to A&A). In a series of individual CASA reductions (w/o SD data + w/o feathering), we have investigated the impact of the different uv-coverages on both the total flux and line velocity structure of our ALMA maps. Our analysis highlights the critical role played by the zero-spacing data at the different stages of the cleaning process. The results of these ALMA+IRAM30m experiments emphasize the need of high-sensitivity SD observations for the analysis of large-scale interferometric maps. During my talk, I will discuss the implications of these experiments on the dawn of the ALMA era and in the context of the new AtLAST telescope.

Cross-Cultural Adaptation of the Profile Fitness Mapping Neck Questionnaire to Brazilian Portuguese: Internal Consistency, Reliability, and Construct and Structural Validity.

PubMed

Ferreira, Mariana Cândido; Björklund, Martin; Dach, Fabiola; Chaves, Thais Cristina

The purpose of this study was to adapt and evaluate the psychometric properties of the ProFitMap-neck to Brazilian Portuguese. The cross-cultural adaptation consisted of 5 stages, and 180 female patients with chronic neck pain participated in the study. A subsample (n = 30) answered the pretest, and another subsample (n = 100) answered the questionnaire a second time. Internal consistency, test-retest reliability, and construct validity (hypothesis testing and structural validity) were estimated. For construct validity, the scores of the questionnaire were correlated with the Neck Disability Index (NDI), and the Hospital Anxiety and Depression Scale (HADS), the Tampa Scale of Kinesiophobia (TSK), and the 36-item Short-Form Health Survey (SF-36). Internal consistency was determined by adequate Cronbach's α values (α > 0.70). Strong reliability was identified by high intraclass correlation coefficients (ICC > 0.75). Construct validity was identified by moderate and strong correlations of the Br-ProFitMap-neck with total NDI score (-0.56 50%, Kaiser-Meyer-Olkin index > 0.50, eigenvalue > 1, and factor loadings > 0.2. Br-ProFitMap-neck had adequate psychometric properties and can be used in clinical settings, as well as research, in patients with chronic neck pain. Copyright © 2017. Published by Elsevier Inc.

Computational prediction of atomic structures of helical membrane proteins aided by EM maps.

PubMed

Kovacs, Julio A; Yeager, Mark; Abagyan, Ruben

2007-09-15

Integral membrane proteins pose a major challenge for protein-structure prediction because only approximately 100 high-resolution structures are available currently, thereby impeding the development of rules or empirical potentials to predict the packing of transmembrane alpha-helices. However, when an intermediate-resolution electron microscopy (EM) map is available, it can be used to provide restraints which, in combination with a suitable computational protocol, make structure prediction feasible. In this work we present such a protocol, which proceeds in three stages: 1), generation of an ensemble of alpha-helices by flexible fitting into each of the density rods in the low-resolution EM map, spanning a range of rotational angles around the main helical axes and translational shifts along the density rods; 2), fast optimization of side chains and scoring of the resulting conformations; and 3), refinement of the lowest-scoring conformations with internal coordinate mechanics, by optimizing the van der Waals, electrostatics, hydrogen bonding, torsional, and solvation energy contributions. In addition, our method implements a penalty term through a so-called tethering map, derived from the EM map, which restrains the positions of the alpha-helices. The protocol was validated on three test cases: GpA, KcsA, and MscL.

Echoes on the motor network: how internal motor control structures afford sensory experience.

PubMed

Burgess, Jed D; Lum, Jarrad A G; Hohwy, Jakob; Enticott, Peter G

2017-12-01

Often, during daily experiences, hearing peers' actions can activate motor regions of the CNS. This activation is termed auditory-motor resonance (AMR) and is thought to represent an internal simulation of one's motor memories. Currently, AMR is demonstrated at the neuronal level in the Macaque and songbird, in conjunction with evidence on a systems level in humans. Here, we review evidence of AMR development from a motor control perspective. In the context of internal modelling, we consider data that demonstrates sensory-guided motor learning and action maintenance, particularly the notion of sensory comparison seen during songbird vocalisation. We suggest that these comparisons generate accurate sensory-to-motor inverse mappings. Furthermore, given reports of mapping decay after songbird learning, we highlight the proposal that the maintenance of these sensorimotor maps potentially explains why frontoparietal regions are activated upon hearing known sounds (i.e., AMR). In addition, we also recommend that activation of these types of internal models outside of action execution may provide an ecological advantage when encountering known stimuli in ambiguous conditions.

International Tectonic Map of the Circumpolar Arctic and its Significance for Geodynamic Interpretations

NASA Astrophysics Data System (ADS)

Petrov, O. V.; Morozov, A.; Shokalsky, S.; Leonov, Y.; Grikurov, G.; Poselov, V.; Pospelov, I.; Kashubin, S.

2011-12-01

In 2003 geological surveys of circum-arctic states initiated the international project "Atlas of Geological Maps of Circumpolar Arctic at 1:5 000000 scale". The project received active support of the UNESCO Commission for the Geological Map of the World (CGMW) and engaged a number of scientists from national academies of sciences and universities. Magnetic and gravity maps were prepared and printed by the Norwegian Geological Survey, and geological map was produced by the Geological Survey of Canada. Completion of these maps made possible compilation of a new Tectonic Map of the Arctic (TeMAr), and this work is now in progress with Russian Geological Research Institute (VSEGEI) in the lead of joint international activities. The map area (north of 60o N) includes three distinct roughly concentric zones. The outer onshore rim is composed of predominantly mature continental crust whose structure and history are illustrated on the map by the age of consolidation of craton basements and orogenic belts. The zone of offshore shelf basins is unique in dimensions with respect to other continental margins of the world. Its deep structure can in most cases be positively related to thinning and rifting of consolidated crust, sometimes to the extent of disruption of its upper layer, whereas the pre-rift evolution can be inferred from geophysical data and extrapolation of geological evidence from the mainland and island archipelagoes. The central Arctic core is occupied by abyssal deeps and intervening bathymetric highs. The Eurasia basin is commonly recognized as a typical oceanic opening separating the Barents-Kara and Lomonosov Ridge passive margins, but geodynamic evolution of Amerasia basin are subject to much controversy, despite significant intensification of earth science researchin the recent years. A growing support to the concept of predominance in the Amerasia basin of continental crust, particularly in the area concealed under High Arctic Large Igneous Province, is based on two lines of evidence: (1) seismic studies and gravity modeling of deep structure of the Earth's crust suggesting a continuity of its main layers from Central Arctic bathymetric highs to the adjoining shelves, and (2) geochrolology and isotope geochemistry of bottom rocks in the central Arctic Ocean indicating the likely occurrence here of Paleozoic supracrustal bedrock possibly resting on a Precambrian basement. In the process of compilation activities all possible effort will be made to reflect in the new international tectonic map our current understanding of present-day distribution of crust types in the Arctic. It will be illustrated by smaller-scale insets depicting, along with the crust types, additional information used for their recognition (e.g. depth to Moho, total sediment thickness, geotransects, etc. This will help to integrate geological history of Central Arctic Ocean with its continental rim and provide a sound basis for testing various paleogeodynamic models.

New "Risk-Targeted" Seismic Maps Introduced into Building Codes

USGS Publications Warehouse

Luco, Nicholas; Garrett, B.; Hayes, J.

2012-01-01

Throughout most municipalities of the United States, structural engineers design new buildings using the U.S.-focused International Building Code (IBC). Updated editions of the IBC are published every 3 years. The latest edition (2012) contains new "risk-targeted maximum considered earthquake" (MCER) ground motion maps, which are enabling engineers to incorporate a more consistent and better defined level of seismic safety into their building designs.

The extinction and dust-to-gas structure of the planetary nebula NGC 7009 observed with MUSE

NASA Astrophysics Data System (ADS)

Walsh, J. R.; Monreal-Ibero, A.; Barlow, M. J.; Ueta, T.; Wesson, R.; Zijlstra, A. A.

2016-04-01

Context. Dust plays a significant role in planetary nebulae. Dust ejected with the gas in the asymptotic giant branch (AGB) phase is subject to the harsh environment of the planetary nebula (PN) while the star is evolving towards a white dwarf. Dust surviving the PN phase contributes to the dust content of the interstellar medium. Aims: The morphology of the internal dust extinction has been mapped for the first time in a PN, the bright nearby Galactic nebula NGC 7009. The morphologies of the gas, dust extinction and dust-to-gas ratio are compared to the structural features of the nebula. Methods: Emission line maps in H Balmer and Paschen lines were formed from analysis of MUSE cubes of NGC 7009 observed during science verification of the instrument. The measured electron temperature and density from the same cube were employed to predict the theoretical H line ratios and derive the extinction distribution across the nebula. After correction for the interstellar extinction to NGC 7009, the internal AV/NH has been mapped for the first time in a PN. Results: The extinction map of NGC 7009 has considerable structure, broadly corresponding to the morphological features of the nebula. The dust-to-gas ratio, AV/NH, increases from 0.7 times the interstellar value to >5 times from the centre towards the periphery of the ionized nebula. The integrated AV/NH is about 2× the mean ISM value. A large-scale feature in the extinction map is a wave, consisting of a crest and trough, at the rim of the inner shell. The nature of this feature is investigated and instrumental and physical causes considered; no convincing mechanisms were identified to produce this feature, other than AGB mass loss variations. Conclusions: Extinction mapping from H emission line imaging of PNe with MUSE provides a powerful tool for revealing the properties of internal dust and the dust-to-gas ratio. Based on observations collected at the European Organisation for Astronomical Research in the Southern Hemisphere under ESO programme 060.A-9347(A).

Damped-Dynamics Flexible Fitting

PubMed Central

Kovacs, Julio A.; Yeager, Mark; Abagyan, Ruben

2008-01-01

In fitting atomic structures into EM maps, it often happens that the map corresponds to a different conformation of the structure. We have developed a new methodology to handle these situations that preserves the covalent geometry of the structure and allows the modeling of large deformations. The first goal is achieved by working in generalized coordinates (positional and internal coordinates), and the second by avoiding harmonic potentials. Instead, we use dampers (shock absorbers) between every pair of atoms, combined with a force field that attracts the atomic structure toward incompletely occupied regions of the EM map. The trajectory obtained by integrating the resulting equations of motion converges to a conformation that, in our validation cases, was very close to the target atomic structure. Compared to current methods, our approach is more efficient and robust against wrong solutions and to overfitting, and does not require user intervention or subjective decisions. Applications to the computation of transition pathways between known conformers, homology and loop modeling, as well as protein docking, are also discussed. PMID:18586844

Damped-dynamics flexible fitting.

PubMed

Kovacs, Julio A; Yeager, Mark; Abagyan, Ruben

2008-10-01

In fitting atomic structures into EM maps, it often happens that the map corresponds to a different conformation of the structure. We have developed a new methodology to handle these situations that preserves the covalent geometry of the structure and allows the modeling of large deformations. The first goal is achieved by working in generalized coordinates (positional and internal coordinates), and the second by avoiding harmonic potentials. Instead, we use dampers (shock absorbers) between every pair of atoms, combined with a force field that attracts the atomic structure toward incompletely occupied regions of the EM map. The trajectory obtained by integrating the resulting equations of motion converges to a conformation that, in our validation cases, was very close to the target atomic structure. Compared to current methods, our approach is more efficient and robust against wrong solutions and to overfitting, and does not require user intervention or subjective decisions. Applications to the computation of transition pathways between known conformers, homology and loop modeling, as well as protein docking, are also discussed.

Three-Dimensional Gene Map of Cancer Cell Types: Structural Entropy Minimisation Principle for Defining Tumour Subtypes

PubMed Central

Li, Angsheng; Yin, Xianchen; Pan, Yicheng

2016-01-01

In this study, we propose a method for constructing cell sample networks from gene expression profiles, and a structural entropy minimisation principle for detecting natural structure of networks and for identifying cancer cell subtypes. Our method establishes a three-dimensional gene map of cancer cell types and subtypes. The identified subtypes are defined by a unique gene expression pattern, and a three-dimensional gene map is established by defining the unique gene expression pattern for each identified subtype for cancers, including acute leukaemia, lymphoma, multi-tissue, lung cancer and healthy tissue. Our three-dimensional gene map demonstrates that a true tumour type may be divided into subtypes, each defined by a unique gene expression pattern. Clinical data analyses demonstrate that most cell samples of an identified subtype share similar survival times, survival indicators and International Prognostic Index (IPI) scores and indicate that distinct subtypes identified by our algorithms exhibit different overall survival times, survival ratios and IPI scores. Our three-dimensional gene map establishes a high-definition, one-to-one map between the biologically and medically meaningful tumour subtypes and the gene expression patterns, and identifies remarkable cells that form singleton submodules. PMID:26842724

Multiseasonal Tree Crown Structure Mapping with Point Clouds from OTS Quadrocopter Systems

NASA Astrophysics Data System (ADS)

Hese, S.; Behrendt, F.

2017-08-01

OTF (Off The Shelf) quadro copter systems provide a cost effective (below 2000 Euro), flexible and mobile platform for high resolution point cloud mapping. Various studies showed the full potential of these small and flexible platforms. Especially in very tight and complex 3D environments the automatic obstacle avoidance, low copter weight, long flight times and precise maneuvering are important advantages of these small OTS systems in comparison with larger octocopter systems. This study examines the potential of the DJI Phantom 4 pro series and the Phantom 3A series for within-stand and forest tree crown 3D point cloud mapping using both within stand oblique imaging in different altitude levels and data captured from a nadir perspective. On a test site in Brandenburg/Germany a beach crown was selected and measured with 3 different altitude levels in Point Of Interest (POI) mode with oblique data capturing and deriving one nadir mosaic created with 85/85 % overlap using Drone Deploy automatic mapping software. Three different flight campaigns were performed, one in September 2016 (leaf-on), one in March 2017 (leaf-off) and one in May 2017 (leaf-on) to derive point clouds from different crown structure and phenological situations - covering the leaf-on and leafoff status of the tree crown. After height correction, the point clouds where used with GPS geo referencing to calculate voxel based densities on 50 × 10 × 10 cm voxel definitions using a topological network of chessboard image objects in 0,5 m height steps in an object based image processing environment. Comparison between leaf-off and leaf-on status was done on volume pixel definitions comparing the attributed point densities per volume and plotting the resulting values as a function of distance to the crown center. In the leaf-off status SFM (structure from motion) algorithms clearly identified the central stem and also secondary branch systems. While the penetration into the crown structure is limited in the leaf-on status (the point cloud is a mainly a description of the interpolated crown surface) - the visibility of the internal crown structure in leaf-off status allows to map also the internal tree structure up to and stopping at the secondary branch level system. When combined the leaf-on and leaf-off point clouds generate a comprehensive tree crown structure description that allows a low cost and detailed 3D crown structure mapping and potentially precise biomass mapping and/or internal structural differentiation of deciduous tree species types. Compared to TLS (Terrestrial Laser Scanning) based measurements the costs are neglectable and in the range of 1500-2500 €. This suggests the approach for low cost but fine scale in-situ applications and/or projects where TLS measurements cannot be derived and for less dense forest stands where POI flights can be performed. This study used the in-copter GPS measurements for geo referencing. Better absolute geo referencing results will be obtained with DGPS reference points. The study however clearly demonstrates the potential of OTS very low cost copter systems and the image attributed GPS measurements of the copter for the automatic calculation of complex 3D point clouds in a multi temporal tree crown mapping context.

Internet-based information system of digital geological data providing

NASA Astrophysics Data System (ADS)

Yuon, Egor; Soukhanov, Mikhail; Markov, Kirill

2015-04-01

One of the Russian Federal аgency of mineral resources problems is to provide the geological information which was delivered during the field operation for the means of federal budget. This information should be present in the current, conditional form. Before, the leading way of presenting geological information were paper geological maps, slices, borehole diagrams reports etc. Technologies of database construction, including distributed databases, technologies of construction of distributed information-analytical systems and Internet-technologies are intensively developing nowadays. Most of geological organizations create their own information systems without any possibility of integration into other systems of the same orientation. In 2012, specialists of VNIIgeosystem together with specialists of VSEGEI started the large project - creating the system of providing digital geological materials with using modern and perspective internet-technologies. The system is based on the web-server and the set of special programs, which allows users to efficiently get rasterized and vectorised geological materials. These materials are: geological maps of scale 1:1M, geological maps of scale 1:200 000 and 1:2 500 000, the fragments of seamless geological 1:1M maps, structural zoning maps inside the seamless fragments, the legends for State geological maps 1:200 000 and 1:1 000 000, full author's set of maps and also current materials for international projects «Atlas of geological maps for Circumpolar Arctic scale 1:5 000 000» and «Atlas of Geologic maps of central Asia and adjacent areas scale 1:2 500 000». The most interesting and functional block of the system - is the block of providing structured and well-formalized geological vector materials, based on Gosgeolkart database (NGKIS), managed by Oracle and the Internet-access is supported by web-subsystem NGKIS, which is currently based on MGS-Framework platform, developed by VNIIgeosystem. One of the leading elements is the web-service, which realizes the interaction of all parts of the system and controls whole the way of the request from the user to the database and back, adopted to the GeoSciML and EarthResourceML view. The experience of creation the Internet-based information system of digital geological data providing, and also previous works, including the developing of web-service of NGKIS-system, allows to tell, that technological realization of presenting Russian geological-cartographical data with using of international standards is possible. While realizing, it could be some difficulties, associated with geological material depth. Russian informational geological model is more deep and wide, than foreign. This means the main problem of using international standards and formats: Russian geological data presentation is possible only with decreasing the data detalisation. But, such a problem becomes not very important, if the service publishes also Russian vocabularies, not associated with international vocabularies. In this case, the international format could be the interchange format to change data between Russian users. The integration into the international projects reaches developing of the correlation schemes between Russian and foreign classificators and vocabularies.

Integrating prior information into microwave tomography Part 1: Impact of detail on image quality.

PubMed

Kurrant, Douglas; Baran, Anastasia; LoVetri, Joe; Fear, Elise

2017-12-01

The authors investigate the impact that incremental increases in the level of detail of patient-specific prior information have on image quality and the convergence behavior of an inversion algorithm in the context of near-field microwave breast imaging. A methodology is presented that uses image quality measures to characterize the ability of the algorithm to reconstruct both internal structures and lesions embedded in fibroglandular tissue. The approach permits key aspects that impact the quality of reconstruction of these structures to be identified and quantified. This provides insight into opportunities to improve image reconstruction performance. Patient-specific information is acquired using radar-based methods that form a regional map of the breast. This map is then incorporated into a microwave tomography algorithm. Previous investigations have demonstrated the effectiveness of this approach to improve image quality when applied to data generated with two-dimensional (2D) numerical models. The present study extends this work by generating prior information that is customized to vary the degree of structural detail to facilitate the investigation of the role of prior information in image formation. Numerical 2D breast models constructed from magnetic resonance (MR) scans, and reconstructions formed with a three-dimensional (3D) numerical breast model are used to assess if trends observed for the 2D results can be extended to 3D scenarios. For the blind reconstruction scenario (i.e., no prior information), the breast surface is not accurately identified and internal structures are not clearly resolved. A substantial improvement in image quality is achieved by incorporating the skin surface map and constraining the imaging domain to the breast. Internal features within the breast appear in the reconstructed image. However, it is challenging to discriminate between adipose and glandular regions and there are inaccuracies in both the structural properties of the glandular region and the dielectric properties reconstructed within this structure. Using a regional map with a skin layer only marginally improves this situation. Increasing the structural detail in the prior information to include internal features leads to reconstructions for which the interface that delineates the fat and gland regions can be inferred. Different features within the glandular region corresponding to tissues with varying relative permittivity values, such as a lesion embedded within glandular structure, emerge in the reconstructed images. Including knowledge of the breast surface and skin layer leads to a substantial improvement in image quality compared to the blind case, but the images have limited diagnostic utility for applications such as tumor response tracking. The diagnostic utility of the reconstruction technique is improved considerably when patient-specific structural information is used. This qualitative observation is supported quantitatively with image metrics. © 2017 American Association of Physicists in Medicine.

High-Resolution Mapping of Thermal History in Polymer Nanocomposites: Gold Nanorods as Microscale Temperature Sensors.

PubMed

Kennedy, W Joshua; Slinker, Keith A; Volk, Brent L; Koerner, Hilmar; Godar, Trenton J; Ehlert, Gregory J; Baur, Jeffery W

2015-12-23

A technique is reported for measuring and mapping the maximum internal temperature of a structural epoxy resin with high spatial resolution via the optically detected shape transformation of embedded gold nanorods (AuNRs). Spatially resolved absorption spectra of the nanocomposites are used to determine the frequencies of surface plasmon resonances. From these frequencies the AuNR aspect ratio is calculated using a new analytical approximation for the Mie-Gans scattering theory, which takes into account coincident changes in the local dielectric. Despite changes in the chemical environment, the calculated aspect ratio of the embedded nanorods is found to decrease over time to a steady-state value that depends linearly on the temperature over the range of 100-200 °C. Thus, the optical absorption can be used to determine the maximum temperature experienced at a particular location when exposure times exceed the temperature-dependent relaxation time. The usefulness of this approach is demonstrated by mapping the temperature of an internally heated structural epoxy resin with 10 μm lateral spatial resolution.

International Maps | Geospatial Data Science | NREL

Science.gov Websites

International Maps International Maps This map collection provides examples of how geographic information system modeling is used in international resource analysis. The images below are samples of

Autonomous exploration and mapping of unknown environments

NASA Astrophysics Data System (ADS)

Owens, Jason; Osteen, Phil; Fields, MaryAnne

2012-06-01

Autonomous exploration and mapping is a vital capability for future robotic systems expected to function in arbitrary complex environments. In this paper, we describe an end-to-end robotic solution for remotely mapping buildings. For a typical mapping system, an unmanned system is directed to enter an unknown building at a distance, sense the internal structure, and, barring additional tasks, while in situ, create a 2-D map of the building. This map provides a useful and intuitive representation of the environment for the remote operator. We have integrated a robust mapping and exploration system utilizing laser range scanners and RGB-D cameras, and we demonstrate an exploration and metacognition algorithm on a robotic platform. The algorithm allows the robot to safely navigate the building, explore the interior, report significant features to the operator, and generate a consistent map - all while maintaining localization.

Imaging and elemental mapping of biological specimens with a dual-EDS dedicated scanning transmission electron microscope

PubMed Central

Wu, J.S.; Kim, A. M.; Bleher, R.; Myers, B.D.; Marvin, R. G.; Inada, H.; Nakamura, K.; Zhang, X.F.; Roth, E.; Li, S.Y.; Woodruff, T. K.; O'Halloran, T. V.; Dravid, Vinayak P.

2013-01-01

A dedicated analytical scanning transmission electron microscope (STEM) with dual energy dispersive spectroscopy (EDS) detectors has been designed for complementary high performance imaging as well as high sensitivity elemental analysis and mapping of biological structures. The performance of this new design, based on a Hitachi HD-2300A model, was evaluated using a variety of biological specimens. With three imaging detectors, both the surface and internal structure of cells can be examined simultaneously. The whole-cell elemental mapping, especially of heavier metal species that have low cross-section for electron energy loss spectroscopy (EELS), can be faithfully obtained. Optimization of STEM imaging conditions is applied to thick sections as well as thin sections of biological cells under low-dose conditions at room- and cryogenic temperatures. Such multimodal capabilities applied to soft/biological structures usher a new era for analytical studies in biological systems. PMID:23500508

Topological defects in electric double layers of ionic liquids at carbon interfaces

DOE PAGES

Black, Jennifer M.; Okatan, Mahmut Baris; Feng, Guang; ...

2015-06-07

The structure and properties of the electrical double layer in ionic liquids is of interest in a wide range of areas including energy storage, catalysis, lubrication, and many more. Theories describing the electrical double layer for ionic liquids have been proposed, however a full molecular level description of the double layer is lacking. To date, studies have been predominantly focused on ion distributions normal to the surface, however the 3D nature of the electrical double layer in ionic liquids requires a full picture of the double layer structure not only normal to the surface, but also in plane. Here wemore » utilize 3D force mapping to probe the in plane structure of an ionic liquid at a graphite interface and report the direct observation of the structure and properties of topological defects. The observation of ion layering at structural defects such as step-edges, reinforced by molecular dynamics simulations, defines the spatial resolution of the method. Observation of defects allows for the establishment of the universality of ionic liquid behavior vs. separation from the carbon surface and to map internal defect structure. In conclusion, these studies offer a universal pathway for probing the internal structure of topological defects in soft condensed matter on the nanometer level in three dimensions.« less

Computational Prediction of Atomic Structures of Helical Membrane Proteins Aided by EM Maps

PubMed Central

Kovacs, Julio A.; Yeager, Mark; Abagyan, Ruben

2007-01-01

Integral membrane proteins pose a major challenge for protein-structure prediction because only ≈100 high-resolution structures are available currently, thereby impeding the development of rules or empirical potentials to predict the packing of transmembrane α-helices. However, when an intermediate-resolution electron microscopy (EM) map is available, it can be used to provide restraints which, in combination with a suitable computational protocol, make structure prediction feasible. In this work we present such a protocol, which proceeds in three stages: 1), generation of an ensemble of α-helices by flexible fitting into each of the density rods in the low-resolution EM map, spanning a range of rotational angles around the main helical axes and translational shifts along the density rods; 2), fast optimization of side chains and scoring of the resulting conformations; and 3), refinement of the lowest-scoring conformations with internal coordinate mechanics, by optimizing the van der Waals, electrostatics, hydrogen bonding, torsional, and solvation energy contributions. In addition, our method implements a penalty term through a so-called tethering map, derived from the EM map, which restrains the positions of the α-helices. The protocol was validated on three test cases: GpA, KcsA, and MscL. PMID:17496035

Role of internal demagnetizing field for the dynamics of a surface-modulated magnonic crystal

NASA Astrophysics Data System (ADS)

Langer, M.; Röder, F.; Gallardo, R. A.; Schneider, T.; Stienen, S.; Gatel, C.; Hübner, R.; Bischoff, L.; Lenz, K.; Lindner, J.; Landeros, P.; Fassbender, J.

2017-05-01

This work aims to demonstrate and understand the key role of local demagnetizing fields in hybrid structures consisting of a continuous thin film with a stripe modulation on top. To understand the complex spin dynamics of these structures, the magnonic crystal was reconstructed in two different ways—performing micromagnetic simulations based on the structural shape as well as based on the internal demagnetizing field, which both are mapped on the nanoscale using electron holography. The simulations yield the frequency-field dependence as well as the angular dependence revealing the governing role of the internal field landscape around the backward-volume geometry. Simple rules for the propagation vector and the mode localization are formulated in order to explain the calculated mode profiles. Treating internal demagnetizing fields equivalent to anisotropies, the complex angle-dependent spin-wave behavior is described for an in-plane rotation of the external field.

Current trends in satellite based emergency mapping - the need for harmonisation

NASA Astrophysics Data System (ADS)

Voigt, Stefan

2013-04-01

During the past years, the availability and use of satellite image data to support disaster management and humanitarian relief organisations has largely increased. The automation and data processing techniques are greatly improving as well as the capacity in accessing and processing satellite imagery in getting better globally. More and more global activities via the internet and through global organisations like the United Nations or the International Charter Space and Major Disaster engage in the topic, while at the same time, more and more national or local centres engage rapid mapping operations and activities. In order to make even more effective use of this very positive increase of capacity, for the sake of operational provision of analysis results, for fast validation of satellite derived damage assessments, for better cooperation in the joint inter agency generation of rapid mapping products and for general scientific use, rapid mapping results in general need to be better harmonized, if not even standardized. In this presentation, experiences from various years of rapid mapping gained by the DLR Center for satellite based Crisis Information (ZKI) within the context of the national activities, the International Charter Space and Major Disasters, GMES/Copernicus etc. are reported. Furthermore, an overview on how automation, quality assurance and optimization can be achieved through standard operation procedures within a rapid mapping workflow is given. Building on this long term rapid mapping experience, and building on the DLR initiative to set in pace an "International Working Group on Satellite Based Emergency Mapping" current trends in rapid mapping are discussed and thoughts on how the sharing of rapid mapping information can be optimized by harmonizing analysis results and data structures are presented. Such an harmonization of analysis procedures, nomenclatures and representations of data as well as meta data are the basis to better cooperate within the global rapid mapping community throughout local/national, regional/supranational and global scales

Mapping the MMPI-2-RF Specific Problems Scales Onto Extant Psychopathology Structures.

PubMed

Sellbom, Martin

2017-01-01

A main objective in developing the Minnesota Multiphasic Personality Inventory-2-Restructured Form (MMPI-2-RF; Ben-Porath & Tellegen, 2008 ) was to link the hierarchical structure of the instrument's scales to contemporary psychopathology and personality models for greater enhancement of construct validity. Initial evidence published with the Restructured Clinical scales has indicated promising results in that the higher order structure of these measures maps onto those reported in the extant psychopathology literature. This study focused on evaluating the internal structure of the Specific Problems and Interest scales, which have not yet been examined in this manner. Two large, mixed-gender outpatient and correctional samples were used. Exploratory factor analyses revealed consistent evidence for a 4-factor structure representing somatization, negative affect, externalizing, and social detachment. Convergent and discriminant validity analyses in the outpatient sample yielded a pattern of results consistent with expectations. These findings add further evidence to indicate that the MMPI-2-RF hierarchy of scales map onto extant psychopathology literature, and also add support to the notion that somatization and detachment should be considered important higher order domains in the psychopathology literature.

Mapping uncharted territory in ice from zeolite networks to ice structures.

PubMed

Engel, Edgar A; Anelli, Andrea; Ceriotti, Michele; Pickard, Chris J; Needs, Richard J

2018-06-05

Ice is one of the most extensively studied condensed matter systems. Yet, both experimentally and theoretically several new phases have been discovered over the last years. Here we report a large-scale density-functional-theory study of the configuration space of water ice. We geometry optimise 74,963 ice structures, which are selected and constructed from over five million tetrahedral networks listed in the databases of Treacy, Deem, and the International Zeolite Association. All prior knowledge of ice is set aside and we introduce "generalised convex hulls" to identify configurations stabilised by appropriate thermodynamic constraints. We thereby rediscover all known phases (I-XVII, i, 0 and the quartz phase) except the metastable ice IV. Crucially, we also find promising candidates for ices XVIII through LI. Using the "sketch-map" dimensionality-reduction algorithm we construct an a priori, navigable map of configuration space, which reproduces similarity relations between structures and highlights the novel candidates. By relating the known phases to the tractably small, yet structurally diverse set of synthesisable candidate structures, we provide an excellent starting point for identifying formation pathways.

Consistent global structures of complex RNA states through multidimensional chemical mapping

PubMed Central

Cheng, Clarence Yu; Chou, Fang-Chieh; Kladwang, Wipapat; Tian, Siqi; Cordero, Pablo; Das, Rhiju

2015-01-01

Accelerating discoveries of non-coding RNA (ncRNA) in myriad biological processes pose major challenges to structural and functional analysis. Despite progress in secondary structure modeling, high-throughput methods have generally failed to determine ncRNA tertiary structures, even at the 1-nm resolution that enables visualization of how helices and functional motifs are positioned in three dimensions. We report that integrating a new method called MOHCA-seq (Multiplexed •OH Cleavage Analysis with paired-end sequencing) with mutate-and-map secondary structure inference guides Rosetta 3D modeling to consistent 1-nm accuracy for intricately folded ncRNAs with lengths up to 188 nucleotides, including a blind RNA-puzzle challenge, the lariat-capping ribozyme. This multidimensional chemical mapping (MCM) pipeline resolves unexpected tertiary proximities for cyclic-di-GMP, glycine, and adenosylcobalamin riboswitch aptamers without their ligands and a loose structure for the recently discovered human HoxA9D internal ribosome entry site regulon. MCM offers a sequencing-based route to uncovering ncRNA 3D structure, applicable to functionally important but potentially heterogeneous states. DOI: http://dx.doi.org/10.7554/eLife.07600.001 PMID:26035425

Integrating prior information into microwave tomography part 2: Impact of errors in prior information on microwave tomography image quality.

PubMed

Kurrant, Douglas; Fear, Elise; Baran, Anastasia; LoVetri, Joe

2017-12-01

The authors have developed a method to combine a patient-specific map of tissue structure and average dielectric properties with microwave tomography. The patient-specific map is acquired with radar-based techniques and serves as prior information for microwave tomography. The impact that the degree of structural detail included in this prior information has on image quality was reported in a previous investigation. The aim of the present study is to extend this previous work by identifying and quantifying the impact that errors in the prior information have on image quality, including the reconstruction of internal structures and lesions embedded in fibroglandular tissue. This study also extends the work of others reported in literature by emulating a clinical setting with a set of experiments that incorporate heterogeneity into both the breast interior and glandular region, as well as prior information related to both fat and glandular structures. Patient-specific structural information is acquired using radar-based methods that form a regional map of the breast. Errors are introduced to create a discrepancy in the geometry and electrical properties between the regional map and the model used to generate the data. This permits the impact that errors in the prior information have on image quality to be evaluated. Image quality is quantitatively assessed by measuring the ability of the algorithm to reconstruct both internal structures and lesions embedded in fibroglandular tissue. The study is conducted using both 2D and 3D numerical breast models constructed from MRI scans. The reconstruction results demonstrate robustness of the method relative to errors in the dielectric properties of the background regional map, and to misalignment errors. These errors do not significantly influence the reconstruction accuracy of the underlying structures, or the ability of the algorithm to reconstruct malignant tissue. Although misalignment errors do not significantly impact the quality of the reconstructed fat and glandular structures for the 3D scenarios, the dielectric properties are reconstructed less accurately within the glandular structure for these cases relative to the 2D cases. However, general agreement between the 2D and 3D results was found. A key contribution of this paper is the detailed analysis of the impact of prior information errors on the reconstruction accuracy and ability to detect tumors. The results support the utility of acquiring patient-specific information with radar-based techniques and incorporating this information into MWT. The method is robust to errors in the dielectric properties of the background regional map, and to misalignment errors. Completion of this analysis is an important step toward developing the method into a practical diagnostic tool. © 2017 American Association of Physicists in Medicine.

Imaging and elemental mapping of biological specimens with a dual-EDS dedicated scanning transmission electron microscope.

PubMed

Wu, J S; Kim, A M; Bleher, R; Myers, B D; Marvin, R G; Inada, H; Nakamura, K; Zhang, X F; Roth, E; Li, S Y; Woodruff, T K; O'Halloran, T V; Dravid, Vinayak P

2013-05-01

A dedicated analytical scanning transmission electron microscope (STEM) with dual energy dispersive spectroscopy (EDS) detectors has been designed for complementary high performance imaging as well as high sensitivity elemental analysis and mapping of biological structures. The performance of this new design, based on a Hitachi HD-2300A model, was evaluated using a variety of biological specimens. With three imaging detectors, both the surface and internal structure of cells can be examined simultaneously. The whole-cell elemental mapping, especially of heavier metal species that have low cross-section for electron energy loss spectroscopy (EELS), can be faithfully obtained. Optimization of STEM imaging conditions is applied to thick sections as well as thin sections of biological cells under low-dose conditions at room and cryogenic temperatures. Such multimodal capabilities applied to soft/biological structures usher a new era for analytical studies in biological systems. Copyright © 2013 Elsevier B.V. All rights reserved.

Mapping of traditional settlements by unmanned airborne vehicles towards architectural restoration

NASA Astrophysics Data System (ADS)

Partsinevelos, Panagiotis; Skoutelis, Nikolaos; Tripolitsiotis, Achilleas; Tsatsarounos, Stelios; Tsitonaki, Anna; Zervos, Panagiotis

2015-06-01

Conservation and restoration of traditional settlements are amongst the actions that international directives proclaim in order to protect our cultural heritage. Towards this end, a mandatory base step in all archaeological and historical practices includes the surveying and mapping of the study area. Often, new, unexplored or abandoned settlements are considered, where dense vegetation, damaged structures and ruins, incorporation of newer structures and renovation characteristics make the precise surveying procedure a labor intensive and time consuming procedure. Unmanned airborne vehicles (UAVs) have been effectively incorporated into several cultural heritage projects mainly for mapping archeological sites. However, the majority of relevant publications lack of quantitative evaluation of their results and when such a validation is provided it is rather a procedural error estimation readily available from the software used, without independent ground truth verification. In this study, a low-cost custom-built hexacopter prototype was employed to deliver accurate mapping of the traditional settlement of Kamariotis in east Crete, Greece. The case of Kamariotis settlement included highly dense urban structures with continuous building forms, curved walls and missing terraces, while wild vegetation made classic geodetic surveying unfeasible. The resulting maps were qualitatively compared against the ones derived using Google Earth and the Greek Cadastral Orthophoto Viewing platforms to evaluate their applicability for architectural mapping. Moreover, the overall precision of the photogrammetric procedure was compared against geodetic surveying.

Quantitative susceptibility mapping: Report from the 2016 reconstruction challenge.

PubMed

Langkammer, Christian; Schweser, Ferdinand; Shmueli, Karin; Kames, Christian; Li, Xu; Guo, Li; Milovic, Carlos; Kim, Jinsuh; Wei, Hongjiang; Bredies, Kristian; Buch, Sagar; Guo, Yihao; Liu, Zhe; Meineke, Jakob; Rauscher, Alexander; Marques, José P; Bilgic, Berkin

2018-03-01

The aim of the 2016 quantitative susceptibility mapping (QSM) reconstruction challenge was to test the ability of various QSM algorithms to recover the underlying susceptibility from phase data faithfully. Gradient-echo images of a healthy volunteer acquired at 3T in a single orientation with 1.06 mm isotropic resolution. A reference susceptibility map was provided, which was computed using the susceptibility tensor imaging algorithm on data acquired at 12 head orientations. Susceptibility maps calculated from the single orientation data were compared against the reference susceptibility map. Deviations were quantified using the following metrics: root mean squared error (RMSE), structure similarity index (SSIM), high-frequency error norm (HFEN), and the error in selected white and gray matter regions. Twenty-seven submissions were evaluated. Most of the best scoring approaches estimated the spatial frequency content in the ill-conditioned domain of the dipole kernel using compressed sensing strategies. The top 10 maps in each category had similar error metrics but substantially different visual appearance. Because QSM algorithms were optimized to minimize error metrics, the resulting susceptibility maps suffered from over-smoothing and conspicuity loss in fine features such as vessels. As such, the challenge highlighted the need for better numerical image quality criteria. Magn Reson Med 79:1661-1673, 2018. © 2017 International Society for Magnetic Resonance in Medicine. © 2017 International Society for Magnetic Resonance in Medicine.

Spaceborne imaging radar - Geologic and oceanographic applications

NASA Technical Reports Server (NTRS)

Elachi, C.

1980-01-01

Synoptic, large-area radar images of the earth's land and ocean surface, obtained from the Seasat orbiting spacecraft, show the potential for geologic mapping and for monitoring of ocean surface patterns. Structural and topographic features such as lineaments, anticlines, folds and domes, drainage patterns, stratification, and roughness units can be mapped. Ocean surface waves, internal waves, current boundaries, and large-scale eddies have been observed in numerous images taken by the Seasat imaging radar. This article gives an illustrated overview of these applications.

Geologic and Fossil Locality Maps of the West-Central Part of the Howard Pass Quadrangle and Part of the Adjacent Misheguk Mountain Quadrangle, Western Brooks Range, Alaska

USGS Publications Warehouse

Dover, James H.; Tailleur, Irvin L.; Dumoulin, Julie A.

2004-01-01

The map depicts the field distribution and contact relations between stratigraphic units, the tectonic relations between major stratigraphic sequences, and the detailed internal structure of these sequences. The stratigraphic sequences formed in a variety of continental margin depositional environments, and subsequently underwent a complexde formational history of imbricate thrust faulting and folding. A compilation of micro and macro fossil identifications is included in this data set.

Diffuse ultrasound monitoring of stress and damage development on a 15-ton concrete beam.

PubMed

Zhang, Yuxiang; Planès, Thomas; Larose, Eric; Obermann, Anne; Rospars, Claude; Moreau, Gautier

2016-04-01

This paper describes the use of an ultrasonic imaging technique (Locadiff) for the Non-Destructive Testing & Evaluation of a concrete structure. By combining coda wave interferometry and a sensitivity kernel for diffuse waves, Locadiff can monitor the elastic and structural properties of a heterogeneous material with a high sensitivity, and can map changes of these properties over time when a perturbation occurs in the bulk of the material. The applicability of the technique to life-size concrete structures is demonstrated through the monitoring of a 15-ton reinforced concrete beam subject to a four-point bending test causing cracking. The experimental results show that Locadiff achieved to (1) detect and locate the cracking zones in the core of the concrete beam at an early stage by mapping the changes in the concrete's micro-structure; (2) monitor the internal stress level in both temporal and spatial domains by mapping the variation in velocity caused by the acousto-elastic effect. The mechanical behavior of the concrete structure is also studied using conventional techniques such as acoustic emission, vibrating wire extensometers, and digital image correlation. The performances of the Locadiff technique in the detection of early stage cracking are assessed and discussed.

Ultra-high resolution, polarization sensitive transversal optical coherence tomography for structural analysis and strain mapping

NASA Astrophysics Data System (ADS)

Wiesauer, Karin; Pircher, Michael; Goetzinger, Erich; Hitzenberger, Christoph K.; Engelke, Rainer; Ahrens, Gisela; Pfeiffer, Karl; Ostrzinski, Ute; Gruetzner, Gabi; Oster, Reinhold; Stifter, David

2006-02-01

Optical coherence tomography (OCT) is a contactless and non-invasive technique nearly exclusively applied for bio-medical imaging of tissues. Besides the internal structure, additionally strains within the sample can be mapped when OCT is performed in a polarization sensitive (PS) way. In this work, we demonstrate the benefits of PS-OCT imaging for non-biological applications. We have developed the OCT technique beyond the state-of-the-art: based on transversal ultra-high resolution (UHR-)OCT, where an axial resolution below 2 μm within materials is obtained using a femtosecond laser as light source, we have modified the setup for polarization sensitive measurements (transversal UHR-PS-OCT). We perform structural analysis and strain mapping for different types of samples: for a highly strained elastomer specimen we demonstrate the necessity of UHR-imaging. Furthermore, we investigate epoxy waveguide structures, photoresist moulds for the fabrication of micro-electromechanical parts (MEMS), and the glass-fibre composite outer shell of helicopter rotor blades where cracks are present. For these examples, transversal scanning UHR-PS-OCT is shown to provide important information about the structural properties and the strain distribution within the samples.

Mapping healthcare systems: a policy relevant analytic tool

PubMed Central

Sekhri Feachem, Neelam; Afshar, Ariana; Pruett, Cristina; Avanceña, Anton L.V.

2017-01-01

Abstract Background In the past decade, an international consensus on the value of well-functioning systems has driven considerable health systems research. This research falls into two broad categories. The first provides conceptual frameworks that take complex healthcare systems and create simplified constructs of interactions and functions. The second focuses on granular inputs and outputs. This paper presents a novel translational mapping tool – the University of California, San Francisco mapping tool (the Tool) - which bridges the gap between these two areas of research, creating a platform for multi-country comparative analysis. Methods Using the Murray-Frenk framework, we create a macro-level representation of a country's structure, focusing on how it finances and delivers healthcare. The map visually depicts the fundamental policy questions in healthcare system design: funding sources and amount spent through each source, purchasers, populations covered, provider categories; and the relationship between these entities. Results We use the Tool to provide a macro-level comparative analysis of the structure of India's and Thailand's healthcare systems. Conclusions As part of the systems strengthening arsenal, the Tool can stimulate debate about the merits and consequences of different healthcare systems structural designs, using a common framework that fosters multi-country comparative analyses. PMID:28541518

A dynamical system view of cerebellar function

NASA Astrophysics Data System (ADS)

Keeler, James D.

1990-06-01

First some previous theories of cerebellar function are reviewed, and deficiencies in how they map onto the neurophysiological structure are pointed out. I hypothesize that the cerebellar cortex builds an internal model, or prediction, of the dynamics of the animal. A class of algorithms for doing prediction based on local reconstruction of attractors are described, and it is shown how this class maps very well onto the structure of the cerebellar cortex. I hypothesize that the climbing fibers multiplex between different trajectories corresponding to different modes of operation. Then the vestibulo-ocular reflex is examined, and experiments to test the proposed model are suggested. The purpose of the presentation here is twofold: (1) To enlighten physiologists to the mathematics of a class of prediction algorithms that map well onto cerebellar architecture. (2) To enlighten dynamical system theorists to the physiological and anatomical details of the cerebellum.

Typicality Shift in Semantic Categories as a Result of Cultural Transition: Evidence from Jewish Argentine Immigrants in Israel.

ERIC Educational Resources Information Center

Shimron, Joseph; Chernitsky, Roberto

1995-01-01

Investigates changes in the internal structure of semantic categories as a result of cultural transition. Examines typicality shifts in semantic categories of Jewish Argentine immigrants in Israel. Presents a model mapping typicality shift patterns onto acculturation patterns. (HB)

3D optical phase reconstruction within PMMA samples using a spectral OCT system

NASA Astrophysics Data System (ADS)

Briones-R., Manuel d. J.; De La Torre-Ibarra, Manuel H.; Mendoza Santoyo, Fernando

2015-08-01

The optical coherence tomography (OCT) technique has proved to be a useful method in biomedical areas such as ophthalmology, dentistry, dermatology, among many others. In all these applications the main target is to reconstruct the internal structure of the samples from which the physician's expertise may recognize and diagnose the existence of a disease. Nowadays OCT has been applied one step further and is used to study the mechanics of some particular type of materials, where the resulting information involves more than just their internal structure and the measurement of parameters such as displacements, stress and strain. Here we report on a spectral OCT system used to image the internal 3D microstructure and displacement maps from a PMMA (Poly-methyl-methacrylate) sample, subjected to a deformation by a controlled three point bending and tilting. The internal mechanical response of the polymer is shown as consecutive 2D images.

The Comet Radar Explorer Mission

NASA Astrophysics Data System (ADS)

Asphaug, Erik; Belton, Mike; Bockelee-Morvan, Dominique; Chesley, Steve; Delbo, Marco; Farnham, Tony; Gim, Yonggyu; Grimm, Robert; Herique, Alain; Kofman, Wlodek; Oberst, Juergen; Orosei, Roberto; Piqueux, Sylvain; Plaut, Jeff; Robinson, Mark; Sava, Paul; Heggy, Essam; Kurth, William; Scheeres, Dan; Denevi, Brett; Turtle, Elizabeth; Weissman, Paul

2014-11-01

Missions to cometary nuclei have revealed major geological surprises: (1) Global scale layers - do these persist through to the interior? Are they a record of primary accretion? (2) Smooth regions - are they landslides originating on the surface? Are they cryovolcanic? (3) Pits - are they impact craters or sublimation pits, or rooted in the interior? Unambiguous answers to these and other questions can be obtained by high definition 3D radar reflection imaging (RRI) of internal structure. RRI can answer many of the great unknowns in planetary science: How do primitive bodies accrete? Are cometary nuclei mostly ice? What drives their spectacular activity and evolution? The Comet Radar Explorer (CORE) mission will image the detailed internal structure of the nucleus of 10P/Tempel 2. This ~16 x 8 x 7 km Jupiter Family Comet (JFC), or its parent body, originated in the outer planets region possibly millions of years before planet formation. CORE arrives post-perihelion and observes the comet’s waning activity from safe distance. Once the nucleus is largely dormant, the spacecraft enters a ~20-km dedicated Radar Mapping Orbit (RMO). The exacting design of the RRI experiment and the precise navigation of RMO will achieve a highly focused 3D radar reflection image of internal structure, to tens of meters resolution, and tomographic images of velocity and attenuation to hundreds of meters resolution, tied to the gravity model and shape. Visible imagers will produce maps of the surface morphology, albedo, color, texture, and photometric response, and images for navigation and shape determination. The cameras will also monitor the structure and dynamics of the coma, and its dusty jets, allowing their correlation in 3D with deep interior structures and surface features. Repeated global high-resolution thermal images will probe the near-surface layers heated by the Sun. Derived maps of thermal inertia will be correlated with the radar boundary response, and photometry and texture, probing surface materials attainable by future robotic excavation missions. Thermal images will reveal areas of sublimation cooling around vents and pits, and the secular response of the outer meters as the nucleus moves farther from the Sun.

Palinspastic reconstruction of structure maps: an automated finite element approach with heterogeneous strain

NASA Astrophysics Data System (ADS)

Dunbar, John A.; Cook, Richard W.

2003-07-01

Existing methods for the palinspastic reconstruction of structure maps do not adequately account for heterogeneous rock strain and hence cannot accurately treat features such as fault terminations and non-cylindrical folds. We propose a new finite element formulation of the map reconstruction problem that treats such features explicitly. In this approach, a model of the map surface, with internal openings that honor the topology of the fault-gap network, is constructed of triangular finite elements. Both model building and reconstruction algorithms are guided by rules relating fault-gap topology to the kinematics of fault motion and are fully automated. We represent the total strain as the sum of a prescribed component of locally homogeneous simple shear and a minimum amount of heterogeneous residual strain. The region within which a particular orientation of simple shear is treated as homogenous can be as small as an individual element or as large as the entire map. For residual strain calculations, we treat the map surface as a hyperelastic membrane. A globally optimum reconstruction is found that unfolds the map while faithfully honoring assigned strain mechanisms, closes fault gaps without overlap or gap and imparts the least possible residual strain in the restored surface. The amount and distribution of the residual strain serves as a diagnostic tool for identifying mapping errors. The method can be used to reconstruct maps offset by any number of faults that terminate, branch and offset each other in arbitrarily complex ways.

75 FR 3959 - Noise Exposure Map Notice for Kona International Airport at Keahole, Keahole, North Kona, HI

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-25

... International Airport at Keahole, Keahole, North Kona, HI AGENCY: Federal Aviation Administration, DOT. ACTION... exposure maps submitted by the State of Hawaii for Kona International Airport at Keahole under the... FAA finds that the noise exposure maps submitted for Kona International Airport at Keahole are in...

Fine-Scale Map of Encyclopedia of DNA Elements Regions in the Korean Population

PubMed Central

Yoo, Yeon-Kyeong; Ke, Xiayi; Hong, Sungwoo; Jang, Hye-Yoon; Park, Kyunghee; Kim, Sook; Ahn, TaeJin; Lee, Yeun-Du; Song, Okryeol; Rho, Na-Young; Lee, Moon Sue; Lee, Yeon-Su; Kim, Jaeheup; Kim, Young J.; Yang, Jun-Mo; Song, Kyuyoung; Kimm, Kyuchan; Weir, Bruce; Cardon, Lon R.; Lee, Jong-Eun; Hwang, Jung-Joo

2006-01-01

The International HapMap Project aims to generate detailed human genome variation maps by densely genotyping single-nucleotide polymorphisms (SNPs) in CEPH, Chinese, Japanese, and Yoruba samples. This will undoubtedly become an important facility for genetic studies of diseases and complex traits in the four populations. To address how the genetic information contained in such variation maps is transferable to other populations, the Korean government, industries, and academics have launched the Korean HapMap project to genotype high-density Encyclopedia of DNA Elements (ENCODE) regions in 90 Korean individuals. Here we show that the LD pattern, block structure, haplotype diversity, and recombination rate are highly concordant between Korean and the two HapMap Asian samples, particularly Japanese. The availability of information from both Chinese and Japanese samples helps to predict more accurately the possible performance of HapMap markers in Korean disease-gene studies. Tagging SNPs selected from the two HapMap Asian maps, especially the Japanese map, were shown to be very effective for Korean samples. These results demonstrate that the HapMap variation maps are robust in related populations and will serve as an important resource for the studies of the Korean population in particular. PMID:16702437

Progress towards mapping the universe of protein folds

PubMed Central

Grant, Alastair; Lee, David; Orengo, Christine

2004-01-01

Although the precise aims differ between the various international structural genomics initiatives currently aiming to illuminate the universe of protein folds, many selectively target protein families for which the fold is unknown. How well can the current set of known protein families and folds be used to estimate the total number of folds in nature, and will structural genomics initiatives yield representatives for all the major protein families within a reasonable time scale? PMID:15128436

The shadow map: a general contact definition for capturing the dynamics of biomolecular folding and function.

PubMed

Noel, Jeffrey K; Whitford, Paul C; Onuchic, José N

2012-07-26

Structure-based models (SBMs) are simplified models of the biomolecular dynamics that arise from funneled energy landscapes. We recently introduced an all-atom SBM that explicitly represents the atomic geometry of a biomolecule. While this initial study showed the robustness of the all-atom SBM Hamiltonian to changes in many of the energetic parameters, an important aspect, which has not been explored previously, is the definition of native interactions. In this study, we propose a general definition for generating atomically grained contact maps called "Shadow". The Shadow algorithm initially considers all atoms within a cutoff distance and then, controlled by a screening parameter, discards the occluded contacts. We show that this choice of contact map is not only well behaved for protein folding, since it produces consistently cooperative folding behavior in SBMs but also desirable for exploring the dynamics of macromolecular assemblies since, it distributes energy similarly between RNAs and proteins despite their disparate internal packing. All-atom structure-based models employing Shadow contact maps provide a general framework for exploring the geometrical features of biomolecules, especially the connections between folding and function.

Multi-temporal mapping of a large, slow-moving earth flow for kinematic interpretation

USGS Publications Warehouse

Guerriero, Luigi; Coe, Jeffrey A.; Revellino, Paola; Guadagno, Francesco M.

2014-01-01

Periodic movement of large, thick landslides on discrete basal surfaces produces modifications of the topographic surface, creates faults and folds, and influences the locations of springs, ponds, and streams (Baum, et al., 1993; Coe et al., 2009). The geometry of the basal-slip surface, which can be controlled by geological structures (e.g., fold axes, faults, etc.; Revellino et al., 2010; Grelle et al., 2011), and spatial variation in the rate of displacement, are responsible for differential deformation and kinematic segmentation of the landslide body. Thus, large landslides are often composed of several distinct kinematic elements. Each element represents a discrete kinematic domain within the main landslide that is broadly characterized by stretching (extension) of the upper part of the landslide and shortening (compression) near the landslide toe (Baum and Fleming, 1991; Guerriero et al., in review). On the basis of this knowledge, we used photo interpretive and GPS field mapping methods to map structures on the surface of the Montaguto earth flow in the Apennine Mountains of southern Italy at a scale of 1:6,000. (Guerriero et al., 2013a; Fig.1). The earth flow has been periodically active since at least 1954. The most extensive and destructive period of activity began on April 26, 2006, when an estimated 6 million m3 of material mobilized, covering and closing Italian National Road SS90, and damaging residential structures (Guerriero et al., 2013b). Our maps show the distribution and evolution of normal faults, thrust faults, strike-slip faults, flank ridges, and hydrological features at nine different dates (October, 1954; June, 1976; June, 1991; June, 2003; June, 2005; May, 2006; October, 2007; July, 2009; and March , 2010) between 1954 and 2010. Within the earth flow we recognized several kinematic elements and associated structures (Fig.2a). Within each kinematic element (e.g. the earth flow neck; Fig.2b), the flow velocity was highest in the middle, and lowest in the upper and lower parts. As the velocity of movement initiated and increased, stretching of the earth flow body induced the formation of normal faults. Conversely, decreasing velocity and shortening of the earth flow induced the formation of thrust faults. A zone with relatively few structures, bounded by strike-slip faults, was located between stretching and shortening areas. These kinematic elements indicate that the overall earth flow was actually composed of numerous linked internal earth flows, with each internal flow having a distinct pattern of structures representative of stretching and shortening (Guerriero et al., in review). These observations indicated that the spatial variation in movement velocity associated with each internal earth flow, mimicked the pattern of movement for the overall earth flow. That is, the earth flow displayed a self-similar pattern at different scales. Furthermore, the presence of other structures such as back-tilted surfaces, flank-ridges, and hydrological elements provide specific information about the shape of the basal topographic surface. Our multi-temporal maps provided a basis for interpretation of the long-term kinematic evolution of the earth flow and the influence of the basal-slip surface on the earth flow movement. Our maps showed that main faults remained stationary through time, despite extensive mobilization and movement of material. This observation indicated that the slip-surface has remained relatively stationary since at least 1954.

Mapping the knowledge utilization field in nursing from 1945 to 2004: a bibliometric analysis.

PubMed

Scott, Shannon D; Profetto-McGrath, Joanne; Estabrooks, Carole A; Winther, Connie; Wallin, Lars; Lavis, John N

2010-12-01

The field of knowledge utilization has been hampered by several issues including: the synonymous use of multiple terms with little attempt at definition precision; an overexamination of knowledge utilization as product, rather than a process; and a lack of progress to cross disciplinary boundaries to advance knowledge development. In order to address the challenges and current knowledge gaps in the knowledge utilization field in nursing, a comprehensive picture of the current state of the field is required. Bibliometric analyses were used to map knowledge utilization literature in nursing as an international field of study, and to identify the structure of its scientific community. Analyses of bibliographic data for 433 articles from the period 1945-2004 demonstrated three trends: (1) there has been significant recent growth and interest in this field, (2) the structure of the scientific knowledge utilization community is evolving, and (3) the Web of Science does not index the majority of journals where this literature is published. In order to enhance the accessibility and profile of this literature, and nursing's scientific literature at large, we encourage the International Academy of Nursing Editors to work collaboratively to increase the number of journals indexed in the Web of Science. ©2010 Sigma Theta Tau International.

Ancestry informative markers for distinguishing between Thai populations based on genome-wide association datasets

PubMed Central

Vongpaisarnsin, Kornkiat; Listman, Jennifer Beth; Malison, Robert T; Gelernter, Joel

2015-01-01

The main purpose of this work was to identify a set of AIMs that stratify the genetic structure and diversity of the Thai population from a high-throughput autosomal genome-wide association study. In this study, more than one million SNPs from the International HapMap database and the Thai depression genome-wide association study have been examined to identify ancestry informative markers (AIMs) that distinguish between Thai populations. An efficient strategy is proposed to identify and characterize such SNPs and to test high-resolution SNP data from international HapMap populations. The best AIMs are identified to stratify the population and to infer genetic ancestry structure. A total of 124 AIMs were clearly clustered geographically across the continent, whereas only 89 AIMs stratified the Thai population from East Asian populations. Finally, a set of 273 AIMs was able to distinguish northern from southern Thai subpopulations. These markers will be of particular value in identifying the ethnic origins in regions where matching by self-reports is unavailable or unreliable, which usually occurs in real forensic cases. PMID:25759192

Ancestry informative markers for distinguishing between Thai populations based on genome-wide association datasets.

PubMed

Vongpaisarnsin, Kornkiat; Listman, Jennifer Beth; Malison, Robert T; Gelernter, Joel

2015-07-01

The main purpose of this work was to identify a set of AIMs that stratify the genetic structure and diversity of the Thai population from a high-throughput autosomal genome-wide association study. In this study, more than one million SNPs from the international HapMap database and the Thai depression genome-wide association study have been examined to identify ancestry informative markers (AIMs) that distinguish between Thai populations. An efficient strategy is proposed to identify and characterize such SNPs and to test high-resolution SNP data from international HapMap populations. The best AIMs are identified to stratify the population and to infer genetic ancestry structure. A total of 124 AIMs were clearly clustered geographically across the continent, whereas only 89 AIMs stratified the Thai population from East Asian populations. Finally, a set of 273 AIMs was able to distinguish northern from southern Thai subpopulations. These markers will be of particular value in identifying the ethnic origins in regions where matching by self-reports is unavailable or unreliable, which usually occurs in real forensic cases. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Mapping healthcare systems: a policy relevant analytic tool.

PubMed

Sekhri Feachem, Neelam; Afshar, Ariana; Pruett, Cristina; Avanceña, Anton L V

2017-07-01

In the past decade, an international consensus on the value of well-functioning systems has driven considerable health systems research. This research falls into two broad categories. The first provides conceptual frameworks that take complex healthcare systems and create simplified constructs of interactions and functions. The second focuses on granular inputs and outputs. This paper presents a novel translational mapping tool - the University of California, San Francisco mapping tool (the Tool) - which bridges the gap between these two areas of research, creating a platform for multi-country comparative analysis. Using the Murray-Frenk framework, we create a macro-level representation of a country's structure, focusing on how it finances and delivers healthcare. The map visually depicts the fundamental policy questions in healthcare system design: funding sources and amount spent through each source, purchasers, populations covered, provider categories; and the relationship between these entities. We use the Tool to provide a macro-level comparative analysis of the structure of India's and Thailand's healthcare systems. As part of the systems strengthening arsenal, the Tool can stimulate debate about the merits and consequences of different healthcare systems structural designs, using a common framework that fosters multi-country comparative analyses. © The Author 2017. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene.

Intensity Mapping Foreground Cleaning with Generalized Needlet Internal Linear Combination

NASA Astrophysics Data System (ADS)

Olivari, L. C.; Remazeilles, M.; Dickinson, C.

2018-05-01

Intensity mapping (IM) is a new observational technique to survey the large-scale structure of matter using spectral emission lines. IM observations are contaminated by instrumental noise and astrophysical foregrounds. The foregrounds are at least three orders of magnitude larger than the searched signals. In this work, we apply the Generalized Needlet Internal Linear Combination (GNILC) method to subtract radio foregrounds and to recover the cosmological HI and CO signals within the IM context. For the HI IM case, we find that GNILC can reconstruct the HI plus noise power spectra with 7.0% accuracy for z = 0.13 - 0.48 (960 - 1260 MHz) and l <~ 400, while for the CO IM case, we find that it can reconstruct the CO plus noise power spectra with 6.7% accuracy for z = 2.4 - 3.4 (26 - 34 GHz) and l <~ 3000.

VNTR internal structure mapping at the {alpha}-globin 3{prime}HVR locus reveals a hierachy of related lineages in oceania

DOE Office of Scientific and Technical Information (OSTI.GOV)

Martinson, J.J.; Clegg, J.B.; Boyce, A.J.

1994-09-01

Analysis of the {alpha}-globin gene complex in Oceania has revealed many different rearrangements which remove one of the adult globin genes. Frequencies of these deletion chromosomes are elevated by malarial resistance conferred by the resulting {alpha}-thalassaemia. One particular deletion chromosome, designated -{alpha}{sup 3.7}III, is found at high levels in Melanesia and Polynesia: RFLP haplotype analysis shows that this deletion is always found on chromosomes bearing the IIIa haplotype and is likely to be the product of one single rearrangement event. A subset of the -{alpha}{sup 3.7}III chromosomes carries a more recent mutation which generates the haemoglobin variant HbJ{sup Tongariki}. Wemore » have characterized the allelic variation at the 3{prime}HVR VNTR locus located 6 kb from the globin genes in each of these groups of chromosomes. We have determined the internal structure of these alleles by RFLP mapping of PCR-amplified DNA: within each group, the allelic diversity results from the insertion and/or deletion of small {open_quotes}motifs{close_quotes} of up to 6 adjacent repeats. Mapping of 3{prime}HVR alleles associated with other haplotypes reveals that these are composed of repeat arrays that are substantially different to those derived from IIIa chromosomes, indicating that interchromosomal recombination between heterologous haplotypes does not account for any of the diversity seen to date. We have recently shown that allelic size variation at the two VNTR loci flanking the {alpha}-globin complex is very closely linked to the haplotypes known to be present at this locus. Here we show that, within a haplotype, VNTR alleles are very closely related to each other on the basis of internal structure and demonstrate that intrachromosomal mutation processes involving small numbers of tandem repeats are the main cause of variation at this locus.« less

Integrating aeromagnetic and Landsat™ 8 data into subsurface structural mapping of Precambrian basement complex

NASA Astrophysics Data System (ADS)

Kayode, John Stephen; Nawawi, M. N. M.; Abdullah, Khiruddin B.; Khalil, Amin E.

2017-01-01

The integration of Aeromagnetic data and remotely sensed imagery with the intents of mapping the subsurface geological structures in part of the South-western basement complex of Nigeria was developed using the PCI Geomatica Software. 2013. The data obtained from the Nigerian Geological Survey Agency; was corrected using Regional Residual Separation of the Total Magnetic field anomalies enhanced, and International Geomagnetic Reference Field removed. The principal objective of this study is, therefore, to introduce a rapid and efficient method of subsurface structural depth estimate and structural index evaluation through the incorporation of the Euler Deconvolution technique into PCI Geomatica 2013 to prospect for subsurface geological structures. The shape and depth of burial helped to define these structures from the regional aeromagnetic map. The method enabled various structural indices to be automatically delineated for an index of between 0.5 SI and 3.0 SI at a maximum depth of 1.1 km that clearly showed the best depths estimate for all the structural indices. The results delineate two major magnetic belts in the area; the first belt shows an elongated ridge-like structure trending mostly along the NorthNortheast-SouthSouthwest and the other anomalies trends primarily in the Northeast, Northwest, Northeast-Southwest parts of the study area that could be attributed to basement complex granitic intrusions from the tectonic history of the area. The majority of the second structures showed various linear structures different from the first structure. Basically, a significant offset was delineated at the core segment of the study area, suggesting a major subsurface geological feature that controls mineralisation in this area.

Deletion of internal structured repeats increases the stability of a leucine-rich repeat protein, YopM

PubMed Central

Barrick, Doug

2011-01-01

Mapping the stability distributions of proteins in their native folded states provides a critical link between structure, thermodynamics, and function. Linear repeat proteins have proven more amenable to this kind of mapping than globular proteins. C-terminal deletion studies of YopM, a large, linear leucine-rich repeat (LRR) protein, show that stability is distributed quite heterogeneously, yet a high level of cooperativity is maintained [1]. Key components of this distribution are three interfaces that strongly stabilize adjacent sequences, thereby maintaining structural integrity and promoting cooperativity. To better understand the distribution of interaction energy around these critical interfaces, we studied internal (rather than terminal) deletions of three LRRs in this region, including one of these stabilizing interfaces. Contrary to our expectation that deletion of structured repeats should be destabilizing, we find that internal deletion of folded repeats can actually stabilize the native state, suggesting that these repeats are destabilizing, although paradoxically, they are folded in the native state. We identified two residues within this destabilizing segment that deviate from the consensus sequence at a position that normally forms a stacked leucine ladder in the hydrophobic core. Replacement of these nonconsensus residues with leucine is stabilizing. This stability enhancement can be reproduced in the context of nonnative interfaces, but it requires an extended hydrophobic core. Our results demonstrate that different LRRs vary widely in their contribution to stability, and that this variation is context-dependent. These two factors are likely to determine the types of rearrangements that lead to folded, functional proteins, and in turn, are likely to restrict the pathways available for the evolution of linear repeat proteins. PMID:21764506

Use of the concept mapping in teaching during a medical rotation of interns: an exploratory study.

PubMed

Kwas, Hamida; Ghédira, Habib

2017-12-01

Concept mapping is an excellent learning toolallowing to stimulate active learning.For this reason, the concept mapping is currently used increasingly in the medical and paramedical field. The aim of our study is to determine the contribution of teaching of medical interns by the concept mapping. Fourteen students enrolled at the same time in a medical rotation in Pulmonology were recruited for this exploratory study. Interns are divided into two groups (A and B).Both groups are taught by the clinical case method, illustrated by a concept mapping for group A interns. The evolution of the knowledge accuracy at post-testing has been greater in the group taught by the method of concept mapping: the number of correct responses increased in all participants of group A versus only 4 of group B. All students taught by concept mapping had at the post-test a note higher than or equal to 10/20 versus only three of the group taught by the method without concept map. The average score was 13 (11-15) in group A versus 10.28 (6-14) in group B. We emphasize the use of concept mapping in teaching especially in the faculty of medicine and we encourage clinicians to use this method in teaching interns in the hospital.

Map Reading beyond Information Given: The Expert Orienteers' Internal Knowledge about Terrain.

ERIC Educational Resources Information Center

Murakoshi, Shin

1990-01-01

Compares novice and expert orienteers' map interpretation skills. Subjects asked to judge terrain from maps, including conditions inferable without corresponding map symbols. Experts' interpretation of identical symbols implies use of experiential knowledge. Internal knowledge characteristics discussed in terms of episodic-semantic memory…

The Molecular Structure of Te146 and Its Derivatives in Drosophila Melanogaster

PubMed Central

Lovering, R.; Harden, N.; Ashburner, M.

1991-01-01

TE146 is a giant transposon of Drosophila melanogaster. It carries two copies of the white and roughest genes, normally found on the X chromosome. The structure of this transposon has been studied at the molecular level. TE146 may transpose to new chromosome positions, excise and be lost from the genome or undergo internal rearrangements. The termini of TE146 are foldback DNA elements (FB); the transposon also carries two internal FB elements. Loss or internal rearrangement of TE146 involves recombination between different FB elements. These events have been mapped molecularly, by taking advantage of the fact that the FB sequences are composed largely of a regular 155-bp repeat sequence that is cut by the restriction enzyme TaqI, and are shown to be nonrandom. We suggest that these FB-FB exchange events occur by mitotic sister-chromatid exchange in the premeiotic germ line. PMID:1649070

A comparison of the International Classification of Functioning, Disability, and Health to the disability tax credit.

PubMed

Conti-Becker, Angela; Doralp, Samantha; Fayed, Nora; Kean, Crystal; Lencucha, Raphael; Leyshon, Rhysa; Mersich, Jackie; Robbins, Shawn; Doyle, Phillip C

2007-01-01

The Disability Tax Credit (DTC) Certification is an assessment tool used to provide Canadians with disability tax relief The International Classification of Functioning, Disability and Health (ICF) provides a universal framework for defining disability. The purpose of this study was to evaluate the DTC and familiarize occupational therapists with the process of mapping measures to the ICF classification system. Concepts within the DTC were identified and mapped to appropriate ICF codes (Cieza et al., 2005). The DTC was linked to 45 unique ICF codes (16 Body Functions, 19 Activities and Participation, and 8 Environmental Factors). The DTC encompasses various domains of the ICF; however, there is no consideration of Personal Factors, Body Structures, and key aspects of Activities and Participation. Refining the DTC to address these aspects will provide an opportunity for fair and just determinations for those who experience disability.

OneGeology: Making the World’s Geological Map Data Accessible Online

NASA Astrophysics Data System (ADS)

Broome, H.; Jackson, I.; Robida, F.; Thorleifson, H.

2009-12-01

OneGeology (http://onegeology.org) is a successful international initiative of the geological surveys of the world and the flagship project of the ‘International Year of Planet Earth’. Its aim is to provide dynamic web access to geological map data covering the world, creating a focus for accessing geological information for everyone. Thanks to the enthusiasm and support of participating nations the initiative has progressed rapidly and geological surveys and the many users of their data are excited about this ground-breaking project. Currently 10 international geoscience organizations have endorsed the initiative and more than 109 countries have agreed to participate. OneGeology works with whatever digital format is available in each country. The target scale is 1:1 million, but the project is pragmatic and accepts a range of scales and the best available data. The initiative recognizes that different nations have differing abilities to participate and transfer of know-how to those who need it is a key aspect of the approach. A key contributor to the success of OneGeology has been its utilization of the latest new web technology and an emerging data exchange standard for geological map data called GeoSciML. GeoSciML (GeoScience Markup Language) is a schema written in GML (Geography Markup Language) for geological data. GeoSciML has the ability to represent both the geography (geometries e.g. polygons, lines and points) and geological attribution in a clear and structured format. OneGeology was launched March 2007 at the inaugural workshop in Brighton England. At that workshop the 43 participating nations developed a declaration of a common objective and principles called the “Brighton Accord” (http://onegeology.org/what_is/accord.html) . Work was initiated immediately and the resulting OneGeology Portal was launched at the International Geological Congress in Oslo in August 2008 by Simon Winchester, author of “The Map that Changed the World”. Since the successful launch, OneGeology participants have continued working both to increase national participation and content, and to put in place a more formal governance structure to oversee the long term evolution of the initiative. OneGeology is an example of collaboration in action and is both multilateral and multinational. In 2007, a group of motivated geoscientists and data managers identified an opportunity and took the initiative to engage their peers to work in concert to achieve a shared objective. OneGeology has facilitated collaborative development of an Internet site that provides unprecedented online access to global geological map data.

Mapping the categories of the Swedish primary health care version of ICD-10 to SNOMED CT concepts: Rule development and intercoder reliability in a mapping trial

PubMed Central

Vikström, Anna; Skånér, Ylva; Strender, Lars-Erik; Nilsson, Gunnar H

2007-01-01

Background Terminologies and classifications are used for different purposes and have different structures and content. Linking or mapping terminologies and classifications has been pointed out as a possible way to achieve various aims as well as to attain additional advantages in describing and documenting health care data. The objectives of this study were: • to explore and develop rules to be used in a mapping process • to evaluate intercoder reliability and the assessed degree of concordance when the 'Swedish primary health care version of the International Classification of Diseases version 10' (ICD-10) is matched to the Systematized Nomenclature of Medicine, Clinical Terms (SNOMED CT) • to describe characteristics in the coding systems that are related to obstacles to high quality mapping. Methods Mapping (interpretation, matching, assessment and rule development) was done by two coders. The Swedish primary health care version of ICD-10 with 972 codes was randomly divided into an allotment of three sets of categories, used in three mapping sequences, A, B and C. Mapping was done independently by the coders and new rules were developed between the sequences. Intercoder reliability was measured by comparing the results after each set. The extent of matching was assessed as either 'partly' or 'completely concordant' Results General principles for mapping were outlined before the first sequence, A. New mapping rules had significant impact on the results between sequences A - B (p < 0.01) and A - C (p < 0.001). The intercoder reliability in our study reached 83%. Obstacles to high quality mapping were mainly a lack of agreement by the coders due to structural and content factors in SNOMED CT and in the current ICD-10 version. The predominant reasons for this were difficulties in interpreting the meaning of the categories in the current ICD-10 version, and the presence of many related concepts in SNOMED CT. Conclusion Mapping from ICD-10-categories to SNOMED CT needs clear and extensive rules. It is possible to reach high intercoder reliability in mapping from ICD-10-categories to SNOMED CT. However, several obstacles to high quality mapping remain due to structure and content characteristics in both coding systems. PMID:17472757

A novel approach to internal crown characterization for coniferous tree species classification

NASA Astrophysics Data System (ADS)

Harikumar, A.; Bovolo, F.; Bruzzone, L.

2016-10-01

The knowledge about individual trees in forest is highly beneficial in forest management. High density small foot- print multi-return airborne Light Detection and Ranging (LiDAR) data can provide a very accurate information about the structural properties of individual trees in forests. Every tree species has a unique set of crown structural characteristics that can be used for tree species classification. In this paper, we use both the internal and external crown structural information of a conifer tree crown, derived from a high density small foot-print multi-return LiDAR data acquisition for species classification. Considering the fact that branches are the major building blocks of a conifer tree crown, we obtain the internal crown structural information using a branch level analysis. The structure of each conifer branch is represented using clusters in the LiDAR point cloud. We propose the joint use of the k-means clustering and geometric shape fitting, on the LiDAR data projected onto a novel 3-dimensional space, to identify branch clusters. After mapping the identified clusters back to the original space, six internal geometric features are estimated using a branch-level analysis. The external crown characteristics are modeled by using six least correlated features based on cone fitting and convex hull. Species classification is performed using a sparse Support Vector Machines (sparse SVM) classifier.

Investigating the Link between Self Directed Learning Readiness and Project-Based Learning Outcomes: The Case of International Masters Students in an Engineering Management Course

ERIC Educational Resources Information Center

Stewart, Rodney A.

2007-01-01

Modern learning approaches increasingly have fewer structured learning activities and more self-directed learning tasks guided through consultation with academics. Such tasks are predominately project-/problem-based where the student is required to follow a freely guided road map to self discovery while simultaneously achieving desired learning…

Proceedings of the international conference on cybernetics and societ

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1985-01-01

This book presents the papers given at a conference on artificial intelligence, expert systems and knowledge bases. Topics considered at the conference included automating expert system development, modeling expert systems, causal maps, data covariances, robot vision, image processing, multiprocessors, parallel processing, VLSI structures, man-machine systems, human factors engineering, cognitive decision analysis, natural language, computerized control systems, and cybernetics.

Examining Neural Correlates of Psychopathology Using a Lesion-Based Approach.

PubMed

Calamia, Matthew; Markon, Kristian E; Sutterer, Matthew J; Tranel, Daniel

2018-06-22

Studies of individuals with focal brain damage have long been used to expand understanding of the neural basis of psychopathology. However, most previous studies were conducted using small sample sizes and relatively coarse methods for measuring psychopathology or mapping brain-behavior relationships. Here, we examined the factor structure and neural correlates of psychopathology in 232 individuals with focal brain damage, using their responses to the Minnesota Multiphasic Personality Inventory-2-Restructured Form (MMPI-2-RF). Factor analysis and voxel-based lesion symptom mapping were used to examine the structure and neural correlates of psychopathology in this sample. Consistent with existing MMPI-2-RF literature, separate internalizing, externalizing, and psychotic symptom dimensions were found. In addition, a somatic dimension likely reflecting neurological symptoms was identified. Damage to the medial temporal lobe, including the hippocampus, was associated with scales related to both internalizing problems and psychoticism. Damage to the medial temporal lobe and orbitofrontal cortex was associated with both a general distrust of others and beliefs that one is being personally targeted by others. These findings provide evidence for the critical role of dysfunction in specific frontal and temporal regions in the development of psychopathology. Copyright © 2018. Published by Elsevier Ltd.

Three-dimensional structure and function of the Paramecium bursaria chlorella virus capsid.

PubMed

Zhang, Xinzheng; Xiang, Ye; Dunigan, David D; Klose, Thomas; Chipman, Paul R; Van Etten, James L; Rossmann, Michael G

2011-09-06

A cryoelectron microscopy 8.5 Å resolution map of the 1,900 Å diameter, icosahedral, internally enveloped Paramecium bursaria chlorella virus was used to interpret structures of the virus at initial stages of cell infection. A fivefold averaged map demonstrated that two minor capsid proteins involved in stabilizing the capsid are missing in the vicinity of the unique vertex. Reconstruction of the virus in the presence of host chlorella cell walls established that the spike at the unique vertex initiates binding to the cell wall, which results in the enveloped nucleocapsid moving closer to the cell. This process is concurrent with the release of the internal viral membrane that was linked to the capsid by many copies of a viral membrane protein in the mature infectous virus. Simultaneously, part of the trisymmetrons around the unique vertex disassemble, probably in part because two minor capsid proteins are absent, causing Paramecium bursaria chlorella virus and the cellular contents to merge, possibly as a result of enzyme(s) within the spike assembly. This may be one of only a few recordings of successive stages of a virus while infecting a eukaryotic host in pseudoatomic detail in three dimensions.

Three-dimensional structure and function of the Paramecium bursaria chlorella virus capsid

PubMed Central

Zhang, Xinzheng; Xiang, Ye; Dunigan, David D.; Klose, Thomas; Chipman, Paul R.; Van Etten, James L.; Rossmann, Michael G.

2011-01-01

A cryoelectron microscopy 8.5 Å resolution map of the 1,900 Å diameter, icosahedral, internally enveloped Paramecium bursaria chlorella virus was used to interpret structures of the virus at initial stages of cell infection. A fivefold averaged map demonstrated that two minor capsid proteins involved in stabilizing the capsid are missing in the vicinity of the unique vertex. Reconstruction of the virus in the presence of host chlorella cell walls established that the spike at the unique vertex initiates binding to the cell wall, which results in the enveloped nucleocapsid moving closer to the cell. This process is concurrent with the release of the internal viral membrane that was linked to the capsid by many copies of a viral membrane protein in the mature infectous virus. Simultaneously, part of the trisymmetrons around the unique vertex disassemble, probably in part because two minor capsid proteins are absent, causing Paramecium bursaria chlorella virus and the cellular contents to merge, possibly as a result of enzyme(s) within the spike assembly. This may be one of only a few recordings of successive stages of a virus while infecting a eukaryotic host in pseudoatomic detail in three dimensions. PMID:21873222

Mapping the Content of the Patient Reported Outcomes Measurement Information System (PROMIS®) Using the International Classification of Functioning, Health and Disability

PubMed Central

Tucker, Carole A; Escorpizo, Reuben; Cieza, Alarcos; Lai, Jin Shei; Stucki, Gerold; Ustun, T. Bedirhan; Kostanjsek, Nenad; Cella, David; Forrest, Christopher B.

2014-01-01

Background The Patient Reported Outcomes Measurement Information System (PROMIS®) is a U.S. National Institutes of Health initiative that has produced self-reported item banks for physical, mental, and social health. Objective To describe the content of PROMIS at the item level using the World Health Organization’s International Classification of Functioning, Disability and Health (ICF). Methods All PROMIS adult items (publicly available as of 2012) were assigned to relevant ICF concepts. The content of the PROMIS adult item banks were then described using the mapped ICF code descriptors. Results The 1006 items in the PROMIS instruments could all be mapped to ICF concepts at the second level of classification, with the exception of 3 items of global or general health that mapped across the first-level classification of ICF activity and participation component (d categories). Individual PROMIS item banks mapped from 1 to 5 separate ICF codes indicating one-to-one, one-to-many and many-to-one mappings between PROMIS item banks and ICF second level classification codes. PROMIS supports measurement of the majority of major concepts in the ICF Body Functions (b) and Activity & Participation (d) components using PROMIS item banks or subsets of PROMIS items that could, with care, be used to develop customized instruments. Given the focus of PROMIS is on measurement of person health outcomes, concepts in body structures (s) and some body functions (b), as well as many ICF environmental factor have minimal coverage in PROMIS. Discussion The PROMIS-ICF mapped items provide a basis for users to evaluate the ICF related content of specific PROMIS instruments, and to select PROMIS instruments in ICF based measurement applications. PMID:24760532

Improved liver R2* mapping by pixel-wise curve fitting with adaptive neighborhood regularization.

PubMed

Wang, Changqing; Zhang, Xinyuan; Liu, Xiaoyun; He, Taigang; Chen, Wufan; Feng, Qianjin; Feng, Yanqiu

2018-08-01

To improve liver R2* mapping by incorporating adaptive neighborhood regularization into pixel-wise curve fitting. Magnetic resonance imaging R2* mapping remains challenging because of the serial images with low signal-to-noise ratio. In this study, we proposed to exploit the neighboring pixels as regularization terms and adaptively determine the regularization parameters according to the interpixel signal similarity. The proposed algorithm, called the pixel-wise curve fitting with adaptive neighborhood regularization (PCANR), was compared with the conventional nonlinear least squares (NLS) and nonlocal means filter-based NLS algorithms on simulated, phantom, and in vivo data. Visually, the PCANR algorithm generates R2* maps with significantly reduced noise and well-preserved tiny structures. Quantitatively, the PCANR algorithm produces R2* maps with lower root mean square errors at varying R2* values and signal-to-noise-ratio levels compared with the NLS and nonlocal means filter-based NLS algorithms. For the high R2* values under low signal-to-noise-ratio levels, the PCANR algorithm outperforms the NLS and nonlocal means filter-based NLS algorithms in the accuracy and precision, in terms of mean and standard deviation of R2* measurements in selected region of interests, respectively. The PCANR algorithm can reduce the effect of noise on liver R2* mapping, and the improved measurement precision will benefit the assessment of hepatic iron in clinical practice. Magn Reson Med 80:792-801, 2018. © 2018 International Society for Magnetic Resonance in Medicine. © 2018 International Society for Magnetic Resonance in Medicine.

Linking of the quality of life in neurological disorders (Neuro-QoL) to the international classification of functioning, disability and health.

PubMed

Wong, Alex W K; Lau, Stephen C L; Cella, David; Lai, Jin-Shei; Xie, Guanli; Chen, Lidian; Chan, Chetwyn C H; Heinemann, Allen W

2017-09-01

The quality of life in neurological disorders (Neuro-QoL) is a U.S. National Institutes of Health initiative that produced a set of self-report measures of physical, mental, and social health experienced by adults or children who have a neurological condition or disorder. To describe the content of the Neuro-QoL at the item level using the World Health Organization's international classification of functioning, disability and health (ICF). We assessed the Neuro-QoL for its content coverage of functioning and disability relative to each of the four ICF domains (i.e., body functions, body structures, activities and participation, and environment). We used second-level ICF three-digit codes to classify items into categories within each ICF domain and computed the percentage of categories within each ICF domain that were represented in the Neuro-QoL items. All items of Neuro-QoL could be mapped to the ICF categories at the second-level classification codes. The activities and participation domain and the mental functions category of the body functions domain were the areas most often represented by Neuro-QoL. Neuro-QoL provides limited coverage of the environmental factors and body structure domains. Neuro-QoL measures map well to the ICF. The Neuro-QoL-ICF-mapped items provide a blueprint for users to select appropriate measures in ICF-based measurement applications.

Eulusmap: An international land resources map utilizing satellite imagery

NASA Technical Reports Server (NTRS)

Paludan, T.; Csati, E.

1978-01-01

In 1972, the International Geographical Union's Commission on World Land Use Survey adopted a project for a land-use map of Europe. Such a map, under the name Eulusmap was started earlier under sponsorship of several government offices in Hungary. Although there was great response from a number of contributors in many countries, it became evident by mid-1974 that the map would contain gaps and some inaccuracies unless additional data sources were utilized. By then, the satellite Landsat-1 had obtained imagery of most of Europe. Using theme extraction techniques, the map was completed in draft form and portions of it displayed at the 23d International Geographical Congress in Moscow during July 1976. Printing of the completed map was accomplished in May 1978.

Dark-field X-ray microscopy for multiscale structural characterization

NASA Astrophysics Data System (ADS)

Simons, H.; King, A.; Ludwig, W.; Detlefs, C.; Pantleon, W.; Schmidt, S.; Snigireva, I.; Snigirev, A.; Poulsen, H. F.

2015-01-01

Many physical and mechanical properties of crystalline materials depend strongly on their internal structure, which is typically organized into grains and domains on several length scales. Here we present dark-field X-ray microscopy; a non-destructive microscopy technique for the three-dimensional mapping of orientations and stresses on lengths scales from 100 nm to 1 mm within embedded sampling volumes. The technique, which allows ‘zooming’ in and out in both direct and angular space, is demonstrated by an annealing study of plastically deformed aluminium. Facilitating the direct study of the interactions between crystalline elements is a key step towards the formulation and validation of multiscale models that account for the entire heterogeneity of a material. Furthermore, dark-field X-ray microscopy is well suited to applied topics, where the structural evolution of internal nanoscale elements (for example, positioned at interfaces) is crucial to the performance and lifetime of macro-scale devices and components thereof.

Fourth international circumpolar arctic vegetation mapping workshop

USGS Publications Warehouse

Raynolds, Martha K.; Markon, C.J.

2002-01-01

During the week of April 10, 2001, the Fourth International Circumpolar Arctic Vegetation Mapping Workshop was held in Moscow, Russia. The purpose of this meeting was to bring together the vegetation scientists working on the Circumpolar Arctic Vegetation Map (CAVM) to (1) review the progress of current mapping activities, (2) discuss and agree upon a standard set of arctic tundra subzones, (3) plan for the production and dissemination of a draft map, and (4) begin work on a legend for the final map.

Spacetime representation of topological phononics

NASA Astrophysics Data System (ADS)

Deymier, Pierre A.; Runge, Keith; Lucas, Pierre; Vasseur, Jérôme O.

2018-05-01

Non-conventional topology of elastic waves arises from breaking symmetry of phononic structures either intrinsically through internal resonances or extrinsically via application of external stimuli. We develop a spacetime representation based on twistor theory of an intrinsic topological elastic structure composed of a harmonic chain attached to a rigid substrate. Elastic waves in this structure obey the Klein–Gordon and Dirac equations and possesses spinorial character. We demonstrate the mapping between straight line trajectories of these elastic waves in spacetime and the twistor complex space. The twistor representation of these Dirac phonons is related to their topological and fermion-like properties. The second topological phononic structure is an extrinsic structure composed of a one-dimensional elastic medium subjected to a moving superlattice. We report an analogy between the elastic behavior of this time-dependent superlattice, the scalar quantum field theory and general relativity of two types of exotic particle excitations, namely temporal Dirac phonons and temporal ghost (tachyonic) phonons. These phonons live on separate sides of a two-dimensional frequency space and are delimited by ghost lines reminiscent of the conventional light cone. Both phonon types exhibit spinorial amplitudes that can be measured by mapping the particle behavior to the band structure of elastic waves.

The large scale structures of the Late Permian Zechstein 3 intra-salt stringer, northern Netherlands

NASA Astrophysics Data System (ADS)

van Gent, H.; Strozyk, F.; Urai, J. L.; de Keijzer, M.; Kukla, P. A.

2012-04-01

The three dimensional study of the internal structure of salt structures on the several different scales is of fundamental importance to understand mechanisms of salt tectonics, for intra-salt storage cavern stability, and for drilling in salt-prone petroleum systems with associated problems like borehole instability and overpressured fluids. While most salt-related studies depict salt as structureless bodies, detailed field-, well- and mining gallery mapping have shown an amazing spectrum of brittle, complexly folded, faulted and boudinaged intra-salt layers ("stringers"), but mostly on a very local scale. First detailed insights into these three-dimensionally heterogeneous and very complex structures of the layered evaporites were provided by observations in modern high-resolution 3D seismic data, such as across the Late Permian Zechstein in the Southern Permian Basin (SPB). In the northern Dutch onshore part of the SPB, the Z2 and Z3 halite interface is characterized by the seismically visible reflections of the 30-150 m thick Z3 anhydrite-carbonate layer that clearly resolves the complex intra-salt structure. This stringer shows a high fragmentation into blocks of several tens of meters to kilometres diameter with complexly folded and faulted structures that correlate to the regionally varying deformation stages of the Zechstein, as it is implied by the shape of Top Salt. After an extensive seismic mapping over the entire northern Netherlands, structures observed include an extensive network of thicker zones, inferred to result from early karstification. Later, this template of relatively strong zones was deformed into large scale folds and boudins as the result of salt tectonics. Non-plane-strain salt flow produced complex fold and boudin geometries that overprint each other. There are some indications of a feedback between the early internal evolution of this salt giant and the position of later salt structures. The stringer has a higher density then the surrounding halite, and in the literature there is some controversy concerning the sinking rates of single stringer fragments. We observed no structures indicative of sinking, but conclude that the present-day position of the blocks can be explained by internal folding of the entire salt section. In the end, this study aims at (i) improving the understanding of the development and dynamics of Zechstein halokinesis, (ii) gaining new insights into the 3D internal deformation in salt, and (iii) a linkage of processes in the layered evaporites with the deformation of the enclosing sub- and supra-salt sediments.

Development and Evaluation of the Telephone Crisis Support Skills Scale.

PubMed

Kitchingman, Taneile A; Wilson, Coralie J; Caputi, Peter; Woodward, Alan; Hunt, Tara

2015-01-01

Although telephone services continue to play an important role in the delivery of front-line crisis support, published evidence of the standardized assessment of such services does not exist to date. To describe the development of the Telephone Crisis Support Skills Scale (TCSSS), an instrument to assess workers' intentions to use recommended skills with callers, and to evaluate its factor structure and reliability. TCSSS items were mapped to a national telephone crisis support practice model. A national sample of workers (n = 210) completed the TCSSS as part of a larger online survey. Principal axis factoring was used to evaluate the structure of the instrument. Internal consistency was assessed by Cronbach's α values. A single factor accounted for more than 40% of the variance within TCSSS ratings, indicating unidimensional structure. Cronbach's α coefficients suggested adequate internal consistency. Results indicate that the TCSSS is an internally consistent, unidimensional scale, sufficiently sensitive to detect workers' skill priorities for different caller problem types. Further study is required to confirm the factor structure and reliability of the TCSSS using workers from different organizations. Following further evaluation, the TCSSS may be applied to assessing readiness for and quality of service delivery.

Updates to building-code maps for the 2015 NEHRP recommended seismic provisions

USGS Publications Warehouse

Luco, Nicolas; Bachman, Robert; Crouse, C.B; Harris, James R.; Hooper, John D.; Kircher, Charles A.; Caldwell, Phillp; Rukstales, Kenneth S.

2015-01-01

With the 2014 update of the U.S. Geological Survey (USGS) National Seismic Hazard Model (NSHM) as a basis, the Building Seismic Safety Council (BSSC) has updated the earthquake ground motion maps in the National Earthquake Hazards Reduction Program (NEHRP) Recommended Seismic Provisions for New Buildings and Other Structures, with partial funding from the Federal Emergency Management Agency. Anticipated adoption of the updated maps into the American Society of Civil Engineers Minimum Design Loads for Building and Other Structures and the International Building and Residential Codes is underway. Relative to the ground motions in the prior edition of each of these documents, most of the updated values are within a ±20% change. The larger changes are, in most cases, due to the USGS NSHM updates, reasons for which are given in companion publications. In some cases, the larger changes are partly due to a BSSC update of the slope of the fragility curve that is used to calculate the risk-targeted ground motions, and/or the introduction by BSSC of a quantitative definition of “active faults” used to calculate deterministic ground motions.

Mapping Optimal Charge Density and Length of ROMP-Based PTDMs for siRNA Internalization.

PubMed

Caffrey, Leah M; deRonde, Brittany M; Minter, Lisa M; Tew, Gregory N

2016-10-10

A fundamental understanding of how polymer structure impacts internalization and delivery of biologically relevant cargoes, particularly small interfering ribonucleic acid (siRNA), is of critical importance to the successful design of improved delivery reagents. Herein we report the use of ring-opening metathesis polymerization (ROMP) methods to synthesize two series of guanidinium-rich protein transduction domain mimics (PTDMs): one based on an imide scaffold that contains one guanidinium moiety per repeat unit, and another based on a diester scaffold that contains two guanidinium moieties per repeat unit. By varying both the degree of polymerization and, in effect, the relative number of cationic charges in each PTDM, the performances of the two ROMP backbones for siRNA internalization were evaluated and compared. Internalization of fluorescently labeled siRNA into Jurkat T cells demonstrated that fluorescein isothiocyanate (FITC)-siRNA internalization had a charge content dependence, with PTDMs containing approximately 40 to 60 cationic charges facilitating the most internalization. Despite this charge content dependence, the imide scaffold yielded much lower viabilities in Jurkat T cells than the corresponding diester PTDMs with similar numbers of cationic charges, suggesting that the diester scaffold is preferred for siRNA internalization and delivery applications. These developments will not only improve our understanding of the structural factors necessary for optimal siRNA internalization, but will also guide the future development of optimized PTDMs for siRNA internalization and delivery.

Air Vehicle Integration and Technology Research (AVIATR). Task Order 0023: Predictive Capability for Hypersonic Structural Response and Life Prediction: Phase 2 - Detailed Design of Hypersonic Cruise Vehicle Hot-Structure

DTIC Science & Technology

2012-02-01

x Approved for public release; distribution unlimited. I-DEAS/ TMG Thermal analysis software IR Initial Review ITAR International Traffic in Arms...the finite element code I- DEAS/ TMG . A mesh refinement study was conducted on the first panel to determine the mesh density required to accurately...ng neer ng, pera ons ec no ogy oe ng esearc ec no ogy • heat transfer analysis conducted with I-DEAS/ TMG exercises mapping of temperatures to

Winter in Northern Europe (WINE). The project Winter in Northern Europe (MAP/WINE): Introduction and outlook

NASA Technical Reports Server (NTRS)

Vonzahn, U.

1989-01-01

The project Winter in Northern Europe (WINE) of the international Middle Atmosphere Program (MAP) comprised a multinational study of the structure, dynamics and composition of the middle atmosphere in winter at high latitudes. Coordinated field measurements were performed during the winter 1983 to 1984 by a large number of ground-based, air-borne, rocket-borne and satellite-borne instruments. Many of the individual experiments were performed in the European sector of the high latitude and polar atmosphere. Studies of the stratosphere, were, in addition, expanded to hemispheric scales by the use of data obtained from remotely sensing satellites. Beyond its direct scientific results, which are reviewed, MAP/WINE has stimulated quite a number of follow-on experiments and projects which address the aeronomy of the middle atmosphere at high and polar latitudes.

Pf1 bacteriophage hydration by magic angle spinning solid-state NMR

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sergeyev, Ivan V.; Bahri, Salima; McDermott, Ann E., E-mail: aem5@columbia.edu

2014-12-14

High resolution two- and three-dimensional heteronuclear correlation spectroscopy ({sup 1}H–{sup 13}C, {sup 1}H–{sup 15}N, and {sup 1}H–{sup 13}C–{sup 13}C HETCOR) has provided a detailed characterization of the internal and external hydration water of the Pf1 virion. This long and slender virion (2000 nm × 7 nm) contains highly stretched DNA within a capsid of small protein subunits, each only 46 amino acid residues. HETCOR cross-peaks have been unambiguously assigned to 25 amino acids, including most external residues 1–21 as well as residues 39–40 and 43–46 deep inside the virion. In addition, the deoxyribose rings of the DNA near the virionmore » axis are in contact with water. The sets of cross-peaks to the DNA and to all 25 amino acid residues were from the same hydration water {sup 1}H resonance; some of the assigned residues do not have exchangeable side-chain protons. A mapping of the contacts onto structural models indicates the presence of water “tunnels” through a highly hydrophobic region of the capsid. The present results significantly extend and modify results from a lower resolution study, and yield a comprehensive hydration surface map of Pf1. In addition, the internal water could be distinguished from external hydration water by means of paramagnetic relaxation enhancement. The internal water population may serve as a conveniently localized magnetization reservoir for structural studies.« less

Transition to international classification of disease version 10, clinical modification: the impact on internal medicine and internal medicine subspecialties.

PubMed

Caskey, Rachel N; Abutahoun, Angelos; Polick, Anne; Barnes, Michelle; Srivastava, Pavan; Boyd, Andrew D

2018-05-04

The US health care system uses diagnostic codes for billing and reimbursement as well as quality assessment and measuring clinical outcomes. The US transitioned to the International Classification of Diseases, 10th Revision, Clinical Modification (ICD-10-CM) on October, 2015. Little is known about the impact of ICD-10-CM on internal medicine and medicine subspecialists. We used a state-wide data set from Illinois Medicaid specified for Internal Medicine providers and subspecialists. A total of 3191 ICD-9-CM codes were used for 51,078 patient encounters, for a total cost of US $26,022,022 for all internal medicine. We categorized all of the ICD-9-CM codes based on the complexity of mapping to ICD-10-CM as codes with complex mapping could result in billing or administrative errors during the transition. Codes found to have complex mapping and frequently used codes (n = 295) were analyzed for clinical accuracy of mapping to ICD-10-CM. Each subspecialty was analyzed for complexity of codes used and proportion of reimbursement associated with complex codes. Twenty-five percent of internal medicine codes have convoluted mapping to ICD-10-CM, which represent 22% of Illinois Medicaid patients, and 30% of reimbursements. Rheumatology and Endocrinology had the greatest proportion of visits and reimbursement associated with complex codes. We found 14.5% of ICD-9-CM codes used by internists, when mapped to ICD-10-CM, resulted in potential clinical inaccuracies. We identified that 43% of diagnostic codes evaluated and used by internists and that account for 14% of internal medicine reimbursements are associated with codes which could result in administrative errors.

Playing Linear Number Board Games Improves Children's Mathematical Knowledge

ERIC Educational Resources Information Center

Siegler, Robert S.; Ramani, Geetha

2009-01-01

The present study focused on two main goals. One was to test the "representational mapping hypothesis": The greater the transparency of the mapping between physical materials and desired internal representations, the greater the learning of the desired internal representation. The implication of the representational mapping hypothesis in the…

The StreamCat Dataset: Accumulated Attributes for NHDPlusV2 Catchments (Version 2.1) for the Conterminous United States: Surficial Lithology in Watershed

EPA Pesticide Factsheets

This dataset represents the density of 18 USGS lithology classes within individual, local NHDPlusV2 catchments and upstream, contributing watersheds(see Data Sources for links to NHDPlusV2 data and USGS). Attributes were calculated for every local NHDPlusV2 catchment and then accumulated to provide watershed-level metrics for USGS lithology data. This data set is derived from the USGS raster map of 18 lithology classes (categorical data type) for the conterminous USA. The map was produced based on texture, internal structure, thickness, and environment of deposition or formation of materials. These 18 lithology classes were summarized by local catchment and by watershed to produce 18 local catchment-level and watershed-level metrics as a categorical data type (see Data Structure and Attribute Information for a description of each metric).

Structural and stratigraphic framework and spatial distribution of permeability of the Atlantic coastal plain, North Carolina to New York

USGS Publications Warehouse

Brown, Philip Monroe; Miller, James A.; Swain, Frederick Morrill

1972-01-01

This report describes and interprets the results of a detailed subsurface mapping program undertaken in that part of the Atlantic Coastal Plain which extends from the South Carolina and North Carolina border through Long Island, N.Y. Data obtained from more than 2,200 wells are analyzed. Seventeen chronostratigraphic units are mapped in the subsurface. They range in age from Jurassic(?) to post-Miocene. The purpose of the mapping program was to determine the external and internal geometry of mappable chronostratigraphic units and to derive and construct a permeability-distribution network for each unit based upon contrasts in the textures and compositions of its contained sediments. The report contains a structure map and a combined isopach, lithofacies, and permeability-distribution map for each of the chronostratigraphic units delineated in the subsurface. In addition, it contains a map of the top of the basement surface. These maps, together with 36 stratigraphic cross sections, present a three-dimensional view of the regional subsurface hydrogeology. They provide focal points of reference for a discussion of regional tectonics, structure, stratigraphy, and permeability distribution. Taken together and in chronologic sequence, the maps constitute a detailed sedimentary model, the first such model to be constructed for the middle Atlantic Coastal Plain. The chronostratigraphic units mapped record a structural history dominated by lateral and vertical movement along a system of intersecting hinge zones. Taphrogeny, related to transcurrent faulting, is the dominant type of deformation that controlled the geometry of the sedimentary model. Twelve of the seventeen chronostratigraphic units mapped have depositional alinements and thickening trends that are independent of the present-day configuration of the underlying basement surface. These 12 units, classified as genetically unrooted units, are assigned to a first-order tectonic stage. A structural model is proposed whose alinements of positive and negative structural features are accordant with the depositional geometry of the chronostratigraphic units assigned to this tectonic stage. The dominant features of the structural model are northeast-plunging half grabens arranged en echelon and bordered by northeast-plunging fault-block anticlines. Tension-type hinge zones that strike north lie athwart the half grabens. Five of the seventeen chronostratigraphic units mapped have depositional alinements and thickening trends that are accordant with the present-day configuration of the underlying basement surface. These five units, classified as genetically rooted units, are assigned to a second-order tectonic stage. A structural model is proposed whose alinements of positive and negative features are accordant with the depositional geometry of the chronostratigraphic units assigned to this tectonic stage. The dominant feature of this model is a graben that stands tangential to southeast-plunging asymmetrical anticlines. Tension-type hinge zones that strike northeast lie athwart the graben. To account for the semiperiodic realinement of structural features that has characterized the history of the region and as a working hypothesis, we propose that the dominant tectonic element, which is present in the area between north Florida and Long Island, N.Y., is a unit-structural block, a ?basement? block, bounded by wrench-fault zones. We propose that forces derived principally from the rotation and precession of the earth act on the unit-structural block and deform it. Two tectonic models are proposed. One model is compatible with the structural and sedimentary geometries that are associated with chronostratigraphic units assigned to a first-order tectonic stage. It features tension-type hinge zones that strike north and shear-type hinge zones that strike northeast. The other model is compatible with the structural and sedimentary geometries associated with chronostratigraphi

New tectonic concept of the Arctic region evolution

NASA Astrophysics Data System (ADS)

Petrov, O. V.; Morozov, A.; Grikurov, G.; Shokalsky, S.; Kashubin, S.; Sobolev, N. V.; Petrov, E.

2012-12-01

The international project "Atlas of Geological Maps of Circumpolar Arctic at 1:5 million scale" was launched in 2003. It was initiated by geological surveys of Circum-Arctic states with active support from the UNESCO Commission for the Geological Map of the World (CGMW). This work engages a number of scientists from national academies of sciences and universities. As of today, international working groups have accomplished the compilation of geological, magnetic and gravity maps at 1:5 million scale. Upon completion of those basic maps, it became possible to undertake the compilation of the Tectonic Map of the Arctic - TeMAr. The final draft of this map is being demonstrated at GeoExpo here in Brisbane. Analysis of the new tectonic map clearly shows the Neoproterozoic - Paleozoic - late Mesozoic Paleoasian oceanic structures. Among those structures are the Neoproterozoic Timan Orogen, the Baikalian fold basement in the Pre-Yenisey zone and the collisional systems of Uralides and Kimmerides whose age becomes successively younger northward from Late Carboniferous - Early Permian to Triassic - Jurassic. Seismic and isotope-geochemistry data recently obtained on Lomonosov Ridge and Mendeleev Rise suggest the possibility that Neoproterozoic-Mesozoic orogenic structures of the High Arctic may incorporate isolated blocks of Early Precambrian continental crust. The north-directed decrease of age refers not only to orogenies caused by gradual closing of the Asian paleo-ocean but also to post-orogenic rift-related processes superposed on continental crust and reflected in the first place in the formation of LIPs. This is well exemplified by transition from the Early Triassic Siberian trap province to Triassic West Siberian province and then to Late Jurassic - Cretaceous, locally Cenozoic basaltic province of the High Arctic. The center of the Canadian Basin so far remains enigmatic: it was probably formed by seafloor spreading that could follow intensive Jurassic-Early Cretaceous continental rifting and volcanic activity. Reactivation of rifting in the Central Arctic at the beginning of Cenozoic led to the onset of spreading 56 million years ago along the emerging Gakkel Ridge and to the subsequent formation of the Eurasian Basin. Approximately 33 million years ago, the newly formed Eurasian oceanic basin connected with the Norwegian-Greenland Basin of the North Atlantic. Combined interpretation of seismostratigraphic data and drilling results suggests that during the Paleogene shallow-water sedimentation in the Central Arctic occurred, which indicates the high-standing sea level. Only in the Early Miocene (about 20 million years ago) the sea bottom sank sharply reaching its present-day depth and causing transition to deep-water deposition. This essential tectonic event is recorded throughout the Central Arctic elevations by a regional unconformity in seismostratigraphic sections. The Cenozoic expansion of the North Atlantic into the Central Arctic occurred across the structural assemblages whose formation was controlled by the preceding evolution of the Asian paleo-ocean.

Mapping Global Research on International Higher Education

ERIC Educational Resources Information Center

Kuzhabekova, Aliya; Hendel, Darwin D.; Chapman, David W.

2015-01-01

The purpose of the study is to map global research in international higher education. Specifically, the study uses bibliometric and social network analysis methods to identify key individuals, institutions, countries, and disciplines contributing to research in international higher education and to investigate patterns of connectivity among…

High-energy x-ray scattering quantification of in-situ-loading-related strain gradients spanning the dentinoenamel junction (DEJ) in bovine tooth specimens.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Almer, J. D.; Stock, S. R.; Northeastern Univ.

2010-08-26

High energy X-ray scattering (80.7keV photons) at station 1-ID of the Advanced Photon Source quantified internal strains as a function of applied stress in mature bovine tooth. These strains were mapped from dentin through the dentinoenamel junction (DEJ) into enamel as a function of applied compressive stress in two small parallelepiped specimens. One specimen was loaded perpendicular to the DEJ and the second parallel to the DEJ. Internal strains in enamel and dentin increased and, as expected from the relative values of the Young's modulus, the observed strains were much higher in dentin than in enamel. Large strain gradients weremore » observed across the DEJ, and the data suggest that the mantle dentin-DEJ-aprismatic enamel structure may shield the near-surface volume of the enamel from large strains. In the enamel, drops in internal strain for applied stresses above 40MPa also suggest that this structure had cracked.« less

Surfing the Pacific Island chains: linking internal wave energetics to coral reef benthic community patterns.

NASA Astrophysics Data System (ADS)

Painter Jones, Matilda; Green, Mattias; Gove, Jamison; Williams, Gareth

2017-04-01

The ocean is saturated with internal waves at tidal frequency. The energy associated with conversion from barotropic to baroclinic can enhance mixing and upwelling at sites of generation and dissipation, which in turn can drive primary production. Hotspots of internal wave generation are located at sudden changes in topography with the Hawaiian archipelago identified as an area of intense internal wave activity. The role of internal waves as a driver of benthic reef community is unexplored and could be key to coral reefs survival in the unknown future. Using a Pacific wide map of internal wave flux and barotropic-to-baroclinic conversion at an unprecedented 1/30th degree resolution, energy budgets were developed for four islands to evaluate dissipation and generation of internal waves. Spatiotemporal variations in benthic community structure were plotted around each island and related to changes in internal wave energetics using a boosted regression tree. Contrasting spatial patterns and species assemblages were seen around islands with distinct internal wave regimes. The relative importance and influence of internal waves on coral reef ecosystems is evaluated.

In search of patient characteristics that may guide empirically based treatment selection for personality disorder patients-a concept map approach.

PubMed

van Manen, J G; Kamphuis, J H; Goossensen, A; Timman, R; Busschbach, J J V; Verheul, R

2012-08-01

Using the concept map method, this study aimed to summarize and describe patient characteristics pertinent to treatment selection for patients with personality disorders (PDs). Initial patient characteristics were derived from the research literature and a survey among Dutch expert clinicians. Concept mapping is a formalized conceptualization procedure that describes the underlying cognitive structures people use in complex tasks, such as treatment allocation. Based on expert opinions of 29 Dutch clinicians, a concept map was generated that yielded eight domains of patient characteristics, i.e., Severity of symptoms, Severity of personality pathology, Ego-adaptive capacities, Motivation and working alliance, Social context, Social demographic characteristics, Trauma, and Treatment history and medical condition. These domains can be ordered along two bipolar axes, running from internal to external concepts and from vulnerability to strength concepts, respectively. Our findings may serve as input for the delineation of algorithms for patient-treatment matching research in PD.

Three-dimensional analysis of magnetometer array data

NASA Technical Reports Server (NTRS)

Richmond, A. D.; Baumjohann, W.

1984-01-01

A technique is developed for mapping magnetic variation fields in three dimensions using data from an array of magnetometers, based on the theory of optimal linear estimation. The technique is applied to data from the Scandinavian Magnetometer Array. Estimates of the spatial power spectra for the internal and external magnetic variations are derived, which in turn provide estimates of the spatial autocorrelation functions of the three magnetic variation components. Statistical errors involved in mapping the external and internal fields are quantified and displayed over the mapping region. Examples of field mapping and of separation into external and internal components are presented. A comparison between the three-dimensional field separation and a two-dimensional separation from a single chain of stations shows that significant differences can arise in the inferred internal component.

Internal gravity wave contributions to global sea surface variability

NASA Astrophysics Data System (ADS)

Savage, A.; Arbic, B. K.; Richman, J. G.; Shriver, J. F.; Buijsman, M. C.; Zamudio, L.; Wallcraft, A. J.; Sharma, H.

2016-02-01

High-resolution (1/12th and 1/25th degree) 41-layer simulations of the HYbrid Coordinate Ocean Model (HYCOM), forced by both atmospheric fields and the astronomical tidal potential, are used to construct global maps of sea-surface height (SSH). The HYCOM output has been separated into steric, non-steric, and total sea-surface height and the maps display variance in subtidal, tidal, and supertidal bands. Two of the global maps are of particular interest in planning for the upcoming Surface Water and Ocean Topography (SWOT) wide-swath satellite altimeter mission; (1) a map of the nonstationary tidal signal (estimated after removing the stationary tidal signal via harmonic analysis), and (2) a map of the steric supertidal contributions, which are dominated by the internal gravity wave continuum. Both of these maps display signals of order 1 cm2, the target accuracy for the SWOT mission. Therefore, both non-stationary internal tides and non-tidal internal gravity waves are likely to be important sources of "noise" that must be accurately removed before examination of lower-frequency phenomena can take place.

Vegetation map for the Hakalau Forest Unit of the Big Island National Wildlife Refuge Complex on the island of Hawai‘i

USGS Publications Warehouse

Jacobi, James D.

2017-01-01

This vegetation map was produced to serve as an updated habitat base for management of natural resources of the Hakalau Forest Unit (HFU) of the Big Island National Wildlife Refuge Complex (Refuge) on the island of Hawai‘i. The map is based on a vegetation map originally produced as part of the U.S. Fish and Wildlife Service’s Hawai‘i Forest Bird Survey to depict the distribution, structure, and composition of plant communities on the island of Hawai‘i as they existed in 1977. The current map has been updated to represent current conditions of plant communities in the HFU, based on WorldView 2 imagery taken in 2012 and very-high-resolution imagery collected by Pictometry International from 2010 to 2014. Thirty-one detailed plant communities are identified on this map, and fourteen of these units are found within the boundaries of HFU. Additionally, the mapped units can be displayed as five tree canopy cover units, three moisture zones units, eight dominant tree species units, and four habitat status units by choosing the various fields to group the units from the map attribute table. This updated map will provide a foundation for the refinement and tracking of management actions on the Refuge for the near future, particularly as the habitats in this area are subject to projected climate change.

2007 International Brain Mapping and Intraoperative Surgical Planning Society’s (IBMISPS) Annual World Congress

DTIC Science & Technology

2008-02-01

and Stroke Two Long Term Consequences of Penetrating Head Injuries : Exacerbated Decline and Post-Traumatic Stress Disorder Key Note speaker: Michael L...an intuitively obvious first principle that if modern medicine hopes to repair adult brains (damaged by war injuries , automobile accidents, stroke ...Imaging Animal Models of Brain Disease Background and Animal Model Quantization of Structure Cerebral Blood Flow Mini- Strokes Cancer Future

The State of WAC/WID in 2010: Methods and Results of the U.S. Survey of the International WAC/WID Mapping Project

ERIC Educational Resources Information Center

Thaiss, Chris; Porter, Tara

2010-01-01

As writing across the curriculum (WAC) has matured and diversified as a concept and as an organizational structure in U.S. higher education, there has arisen a need for accurate, up-to-date information on the presence and characteristics of WAC and writing-in-the-disciplines (WID) programs. Following on the only previous nationwide survey of…

Development of Solar Research

NASA Astrophysics Data System (ADS)

Wittmann, Axel D.; Wolfschmidt, Gudrun; Duerbeck, Hilmar W.

Originally based on a workshop on “Development of Solar Research”, held in Freiburg/Breisgau, this book contains articles on megalithic structures, the Nebra sky-disk, ancient sun cults, the observation of sunspots, the photography of the sun during eclipses, eclipse maps and expeditions, solar telescopes, solar physics during the Nazi era, archives of solar observations, scientific ballooning for solar research, site-testing on the Canary Islands, as well as on international cooperation.

Cross-mapping the ICNP with NANDA, HHCC, Omaha System and NIC for unified nursing language system development. International Classification for Nursing Practice. International Council of Nurses. North American Nursing Diagnosis Association. Home Health Care Classification. Nursing Interventions Classification.

PubMed

Hyun, S; Park, H A

2002-06-01

Nursing language plays an important role in describing and defining nursing phenomena and nursing actions. There are numerous vocabularies describing nursing diagnoses, interventions and outcomes in nursing. However, the lack of a standardized unified nursing language is considered a problem for further development of the discipline of nursing. In an effort to unify the nursing languages, the International Council of Nurses (ICN) has proposed the International Classification for Nursing Practice (ICNP) as a unified nursing language system. The purpose of this study was to evaluate the inclusiveness and expressiveness of the ICNP terms by cross-mapping them with the existing nursing terminologies, specifically the North American Nursing Diagnosis Association (NANDA) taxonomy I, the Omaha System, the Home Health Care Classification (HHCC) and the Nursing Interventions Classification (NIC). Nine hundred and seventy-four terms from these four classifications were cross-mapped with the ICNP terms. This was performed in accordance with the Guidelines for Composing a Nursing Diagnosis and Guidelines for Composing a Nursing Intervention, which were suggested by the ICNP development team. An expert group verified the results. The ICNP Phenomena Classification described 87.5% of the NANDA diagnoses, 89.7% of the HHCC diagnoses and 72.7% of the Omaha System problem classification scheme. The ICNP Action Classification described 79.4% of the NIC interventions, 80.6% of the HHCC interventions and 71.4% of the Omaha System intervention scheme. The results of this study suggest that the ICNP has a sound starting structure for a unified nursing language system and can be used to describe most of the existing terminologies. Recommendations for the addition of terms to the ICNP are provided.

Swath sonar mapping of Earth's submarine plate boundaries

NASA Astrophysics Data System (ADS)

Carbotte, S. M.; Ferrini, V. L.; Celnick, M.; Nitsche, F. O.; Ryan, W. B. F.

2014-12-01

The recent loss of Malaysia Airlines flight MH370 in an area of the Indian Ocean where less than 5% of the seafloor is mapped with depth sounding data (Smith and Marks, EOS 2014) highlights the striking lack of detailed knowledge of the topography of the seabed for much of the worlds' oceans. Advances in swath sonar mapping technology over the past 30 years have led to dramatic improvements in our capability to map the seabed. However, the oceans are vast and only an estimated 10% of the seafloor has been mapped with these systems. Furthermore, the available coverage is highly heterogeneous and focused within areas of national strategic priority and community scientific interest. The major plate boundaries that encircle the globe, most of which are located in the submarine environment, have been a significant focus of marine geoscience research since the advent of swath sonar mapping. While the location of these plate boundaries are well defined from satellite-derived bathymetry, significant regions remain unmapped at the high-resolutions provided by swath sonars and that are needed to study active volcanic and tectonic plate boundary processes. Within the plate interiors, some fossil plate boundary zones, major hotspot volcanoes, and other volcanic provinces have been the focus of dedicated research programs. Away from these major tectonic structures, swath mapping coverage is limited to sparse ocean transit lines which often reveal previously unknown deep-sea channels and other little studied sedimentary structures not resolvable in existing low-resolution global compilations, highlighting the value of these data even in the tectonically quiet plate interiors. Here, we give an overview of multibeam swath sonar mapping of the major plate boundaries of the globe as extracted from public archives. Significant quantities of swath sonar data acquired from deep-sea regions are in restricted-access international archives. Open access to more of these data sets would enable global comparisons of plate boundary structures and processes and could facilitate a more coordinated approach to optimizing the future acquisition of these high-value data by the global research community.

Northward extension of Carolina slate belt stratigraphy and structure, South-Central Virginia: Results from geologic mapping

USGS Publications Warehouse

Hackley, P.C.; Peper, J.D.; Burton, W.C.; Horton, J. Wright

2007-01-01

Geologic mapping in south-central Virginia demonstrates that the stratigraphy and structure of the Carolina slate belt extend northward across a steep thermal gradient into upper amphibolite-facies correlative gneiss and schist. The Neoproterozoic greenschist-facies Hyco, Aaron, and Virgilina Formations were traced northward from their type localities near Virgilina, Virginia, along a simple, upright, northeast-trending isoclinal syncline. This syncline is called the Dryburg syncline and is a northern extension of the more complex Virgilina synclinorium. Progressively higher-grade equivalents of the Hyco and Aaron Formations were mapped northward along the axial trace of the refolded and westwardly-overturned Dryburg syncline through the Keysville and Green Bay 7.5-minute quadrangles, and across the northern end of the Carolina slate belt as interpreted on previous geologic maps. Hyco rocks, including felsic metatuff, metawacke, and amphibolite, become gneisses upgrade with areas of local anatexis and the segregation of granitic melt into leucosomes with biotite selvages. Phyllite of the Aaron Formation becomes garnet-bearing mica schist. Aaron Formation rocks disconformably overlie the primarily felsic volcanic and volcaniclastic rocks of the Hyco Formation as evidenced by repeated truncation of internal contacts within the Hyco on both limbs of the Dryburg syncline at the Aaron-Hyco contact. East-northeast-trending isograds, defined successively by the first appearance of garnet, then kyanite ?? staurolite in sufficiently aluminous rocks, are superposed on the stratigraphic units and synclinal structure at moderate to high angles to strike. The textural distinction between gneisses and identifiable sedimentary structures occurs near the kyanite ?? staurolite-in isograd. Development of the steep thermal gradient and regional penetrative fabric is interpreted to result from emplacement of the Goochland terrane adjacent to the northern end of the slate belt during Alleghanian orogenesis. This mapping study indicates that the Carolina slate belt does not terminate on the north against through-going faults or rest on higher-grade basement as previously suggested.

Mapping nuclear craters on Enewetak Atoll, Marshall Islands

USGS Publications Warehouse

Hampson, John C., Jr.

1986-01-01

In 1984, the U.S. Geological Survey conducted a detailed geologic analysis of two nuclear test craters at Enewetak Atoll, Marshall Islands, on behalf of the Defense Nuclear Agency. A multidisciplinary task force mapped the morphology, surface character, and subsurface structure of two craters, OAK and KOA. The field mapping techniques include echo sounding, sidescan sonar imaging, single-channel and multichannel seismic reflection profiling, a seismic refraction survey, and scuba and submersible operations. All operations had to be navigated precisely and correlatable with subsequent drilling and sampling operations. Mapping with a high degree of precision at scales as large as 1:1500 required corrections that often are not considered in marine mapping. Corrections were applied to the bathymetric data for location of the echo- sounding transducer relative to the navigation transponder on the ship and for transducer depth, speed of sound, and tidal variations. Sidescan sonar, single-channel seismic reflection, and scuba and submersible data were correlated in depth and map position with the bathymetric data to provide a precise, internally consistent data set. The multichannel and refraction surveys were conducted independently but compared well with bathymetry. Examples drawn from processing the bathymetric, sidescan sonar, and single- channel reflection data help illustrate problems and procedures in precision mapping.

Terrestrial Ecosystems-Surficial Lithology of the Conterminous United States

USGS Publications Warehouse

Cress, Jill; Soller, David; Sayre, Roger G.; Comer, Patrick; Warner, Harumi

2010-01-01

As part of an effort to map terrestrial ecosystems, the U.S. Geological Survey (USGS) has generated a new classification of the lithology of surficial materials to be used in creating maps depicting standardized, terrestrial ecosystem models for the conterminous United States. The ecosystems classification used in this effort was developed by NatureServe. A biophysical stratification approach, developed for South America and now being implemented globally, was used to model the ecosystem distributions. This ecosystem mapping methodology is transparent, replicable, and rigorous. Surficial lithology strongly influences the differentiation and distribution of terrestrial ecosystems, and is one of the key input layers in this biophysical stratification. These surficial lithology classes were derived from the USGS map 'Surficial Materials in the Conterminous United States,' which was based on texture, internal structure, thickness, and environment of deposition or formation of materials. This original map was produced from a compilation of regional surficial and bedrock geology source maps using broadly defined common map units for the purpose of providing an overview of the existing data and knowledge. For the terrestrial ecosystem effort, the 28 lithology classes of Soller and Reheis (2004) were generalized and then reclassified into a set of 17 lithologies that typically control or influence the distribution of vegetation types.

Release of the World Digital Magnetic Anomaly Map version 2 (WDMAM v2) scheduled

NASA Astrophysics Data System (ADS)

Dyment, Jérôme; Lesur, Vincent; Choi, Yujin; Hamoudi, Mohamed; Thébault, Erwan; Catalan, Manuel

2015-04-01

The World Digital Magnetic Anomaly Map is an international initiative carried out under the auspices of the International Association of Geomagnetism and Aeronomy (IAGA) and the Commission for the Geological Map of the World (CGMW). A first version of the map has been published and distributed eight years ago (WDMAM v1; Korhonen et al., 2007). After a call for an improved second version of the map in 2011, the slow process of data compilation, map preparation, evaluation and finalization is near completion, and the WDMAM v2 will be released at the International Union of Geophysics and Geodesy (IUGG) meeting to be held in Prag in June-July 2015. In this presentation we display several shortcomings of the WDMAM v1, both on continental and oceanic areas, that are hopefully alleviated in the WDMAM v2, and discuss the process leading to the new map. We reiterate a long-standing call for aeromagnetic and marine magnetic data contribution, and explore future directions to pursue the effort toward a more complete, higher resolution magnetic anomaly map of the World.

Observation of stable Néel skyrmions in cobalt/palladium multilayers with Lorentz transmission electron microscopy

DOE PAGES

Pollard, Shawn D.; Garlow, Joseph A.; Yu, Jiawei; ...

2017-03-10

Néel skyrmions are of high interest due to their potential applications in a variety of spintronic devices, currently accessible in ultrathin heavy metal/ferromagnetic bilayers and multilayers with a strong Dzyaloshinskii–Moriya interaction. Here in this paper we report on the direct imaging of chiral spin structures including skyrmions in an exchange-coupled cobalt/palladium multilayer at room temperature with Lorentz transmission electron microscopy, a high-resolution technique previously suggested to exhibit no Néel skyrmion contrast. Phase retrieval methods allow us to map the internal spin structure of the skyrmion core, identifying a 25 nm central region of uniform magnetization followed by a larger regionmore » characterized by rotation from in- to out-of-plane. The formation and resolution of the internal spin structure of room temperature skyrmions without a stabilizing out-of-plane field in thick magnetic multilayers opens up a new set of tools and materials to study the physics and device applications associated with chiral ordering and skyrmions.« less

Nanoscale Imaging of Buried Structures via Scanning Near-Field Ultrasound Holography

NASA Astrophysics Data System (ADS)

Shekhawat, Gajendra S.; Dravid, Vinayak P.

2005-10-01

A nondestructive imaging method, scanning near-field ultrasound holography (SNFUH), has been developed that provides depth information as well as spatial resolution at the 10- to 100-nanometer scale. In SNFUH, the phase and amplitude of the scattered specimen ultrasound wave, reflected in perturbation to the surface acoustic standing wave, are mapped with a scanning probe microscopy platform to provide nanoscale-resolution images of the internal substructure of diverse materials. We have used SNFUH to image buried nanostructures, to perform subsurface metrology in microelectronic structures, and to image malaria parasites in red blood cells.

Time Resolved Digital PIV Measurements of Flow Field Cyclic Variation in an Optical IC Engine

NASA Astrophysics Data System (ADS)

Jarvis, S.; Justham, T.; Clarke, A.; Garner, C. P.; Hargrave, G. K.; Halliwell, N. A.

2006-07-01

Time resolved digital particle image velocimetry (DPIV) experimental data is presented for the in-cylinder flow field development of a motored four stroke spark ignition (SI) optical internal combustion (IC) engine. A high speed DPIV system was employed to quantify the velocity field development during the intake and compression stroke at an engine speed of 1500 rpm. The results map the spatial and temporal development of the in-cylinder flow field structure allowing comparison between traditional ensemble average and cycle average flow field structures. Conclusions are drawn with respect to engine flow field cyclic variations.

The rotational order-disorder structure of the reversibly photoswitchable red fluorescent protein rsTagRFP.

PubMed

Pletnev, Sergei; Subach, Fedor V; Verkhusha, Vladislav V; Dauter, Zbigniew

2014-01-01

The rotational order-disorder (OD) structure of the reversibly photoswitchable fluorescent protein rsTagRFP is discussed in detail. The structure is composed of tetramers of 222 symmetry incorporated into the lattice in two different orientations rotated 90° with respect to each other around the crystal c axis and with tetramer axes coinciding with the crystallographic twofold axes. The random distribution of alternatively oriented tetramers in the crystal creates the rotational OD structure with statistically averaged I422 symmetry. Despite order-disorder pathology, the structure of rsTagRFP has electron-density maps of good quality for both non-overlapping and overlapping parts of the model. The crystal contacts, crystal internal architecture and a possible mechanism of rotational OD crystal formation are discussed.

Analysis

NASA Astrophysics Data System (ADS)

Abdelazeem, Maha; El-Sawy, El-Sawy K.; Gobashy, Mohamed M.

2013-06-01

Ar Rika fault zone constitutes one of the two major parts of the NW-SE Najd fault system (NFS), which is one of the most prominent structural features located in the east of the center of the Arabian Shield, Saudi Arabia. By using Enhancement Thematic Mapper data (ETM+) and Principle Component Analysis (PCA), surface geological characteristics, distribution of rock types, and the different trends of linear features and faults are determined in the study area. First and second order magnetic gradients of the geomagnetic field at the North East of Wadi Ar Rika have been calculated in the frequency domain to map both surface and subsurface lineaments and faults. Lineaments as deduced from previous studies, suggest an extension of the NFS beneath the cover rocks in the study area. In the present study, integration of magnetic gradients and remote sensing analysis that resulted in different valuable derivative maps confirm the subsurface extension of some of the surface features. The 3D Euler deconvolution, the total gradient, and the tilt angle maps have been utilized to determine accurately the distribution of shear zones, the tectonic implications, and the internal structures of the terranes in the Ar Rika quadrangle in three dimensions.

Motivation, emotion regulation, and the latent structure of psychopathology: An integrative and convergent historical perspective.

PubMed

Beauchaine, Theodore P; Zisner, Aimee

2017-09-01

Motivational models of psychopathology have long been advanced by psychophysiologists, and have provided key insights into neurobiological mechanisms of a wide range of psychiatric disorders. These accounts emphasize individual differences in activity and reactivity of bottom-up, subcortical neural systems of approach and avoidance in affecting behavior. Largely independent literatures emphasize the roles of top-down, cortical deficits in emotion regulation and executive function in conferring vulnerability to psychopathology. To date however, few models effectively integrate functions performed by bottom-up emotion generation system with those performed by top-down emotion regulation systems in accounting for alternative expressions of psychopathology. In this article, we present such a model, and describe how it accommodates the well replicated bifactor structure of psychopathology. We describe how excessive approach motivation maps directly into externalizing liability, how excessive passive avoidance motivation maps directly into internalizing liability, and how emotion dysregulation and executive function map onto general liability. This approach is consistent with the Research Domain Criteria initiative, which assumes that a limited number of brain systems interact to confer vulnerability to many if not most forms of psychopathology. Copyright © 2017 Elsevier B.V. All rights reserved.

Deconstructing the shallow internal structure of the Moon using GRAIL gravity and LOLA topography

NASA Astrophysics Data System (ADS)

Zuber, M. T.

2015-12-01

Globally-distributed, high-resolution gravity and topography observations of the Moon from the Gravity Recovery and Interior Laboratory (GRAIL) mission and Lunar Orbiter Laser Altimeter (LOLA) instrument aboard the Lunar Reconnaissance Orbiter (LRO) spacecraft afford the unprecedented opportunity to explore the shallow internal structure of the Moon. Gravity and topography can be combined to produce Bouguer gravity that reveals the distribution of mass in the subsurface, with high degrees in the spherical harmonic expansion of the Bouguer anomalies sensitive to shallowest structure. For isolated regions of the lunar highlands and several basins we have deconstructed the gravity field and mapped the subsurface distribution of density anomalies. While specified spherical harmonic degree ranges can be used to estimate contributions at different depths, such analyses require considerable caution in interpretation. A comparison of filtered Bouguer gravity with forward models of disk masses with plausible densities illustrates the interdependencies of the gravitational power of density anomalies with depth and spatial scale. The results have implications regarding the limits of interpretation of lunar subsurface structure.

Structure of the Pseudomonas aeruginosa Type IVa Pilus Secretin at 7.4 Å.

PubMed

Koo, Jason; Lamers, Ryan P; Rubinstein, John L; Burrows, Lori L; Howell, P Lynne

2016-10-04

Type IVa pili (T4aP) function as bacterial virulence factors. T4aP pass through the outer membranes of Gram-negative bacteria via homo-oligomeric secretins. We present a 7.4 Å cryoelectron microscopy structure of the Pseudomonas aeruginosa PilQ secretin. Peripheral and internal features show that the secretin is composed of 14 subunits with C7 symmetry. The channel is a ribbed cylinder with central peripheral spokes and a central gate closed on the periplasmic side. The structure suggests that during pilus extrusion, the central gate is displaced to the interior walls and that no additional conformational changes are required, as the internal diameter can accommodate the pilus. The N1 domain was resolved, while the N0 and the N-terminal β-domains proposed to bind peptidoglycan were absent in class average images and the final 3D map, indicating a high flexibility. These data provide the highest-resolution structure to date of a T4aP secretin. Copyright © 2016 Elsevier Ltd. All rights reserved.

Usable, Real-Time, Interactive Spoken Language Systems

DTIC Science & Technology

1994-09-01

Similarly, we included derivations (mostly plurals and possessives) of many open-class words in the domnain. We also added about 400 concatenated word...UueraiCe’l~ usinig a system of’ ’realization 1111C, %%. hiCh map) thle gr-aimmlatcal relation anl argumlent bears to the head onto thle semantic relatio ...syntactic categories as well. Representations of this form contain significantly more internal structure than specialized sublanguage models. This can be

Middle Atmosphere Program. Handbook for MAP. Volume 16: Atmospheric Structure and Its Variation in the Region 20 to 120 Km. Draft of a New Reference Middle Atmosphere

NASA Technical Reports Server (NTRS)

Labitzke, K. (Editor); Barnett, J. J. (Editor); Edwards, B. (Editor)

1985-01-01

A draft of a new reference atmosphere for the region between 20 and 80 km which depends largely on recent satellite experiments covering the globe from 80 deg S to 80 deg N is given. A separate international tropical reference atmosphere is given, as well as reference ozone models for the middle atmosphere.

Modeling Chinese ionospheric layer parameters based on EOF analysis

NASA Astrophysics Data System (ADS)

Yu, You; Wan, Weixing; Xiong, Bo; Ren, Zhipeng; Zhao, Biqiang; Zhang, Yun; Ning, Baiqi; Liu, Libo

2015-05-01

Using 24-ionosonde observations in and around China during the 20th solar cycle, an assimilative model is constructed to map the ionospheric layer parameters (foF2, hmF2, M(3000)F2, and foE) over China based on empirical orthogonal function (EOF) analysis. First, we decompose the background maps from the International Reference Ionosphere model 2007 (IRI-07) into different EOF modes. The obtained EOF modes consist of two factors: the EOF patterns and the corresponding EOF amplitudes. These two factors individually reflect the spatial distributions (e.g., the latitudinal dependence such as the equatorial ionization anomaly structure and the longitude structure with east-west difference) and temporal variations on different time scales (e.g., solar cycle, annual, semiannual, and diurnal variations) of the layer parameters. Then, the EOF patterns and long-term observations of ionosondes are assimilated to get the observed EOF amplitudes, which are further used to construct the Chinese Ionospheric Maps (CIMs) of the layer parameters. In contrast with the IRI-07 model, the mapped CIMs successfully capture the inherent temporal and spatial variations of the ionospheric layer parameters. Finally, comparison of the modeled (EOF and IRI-07 model) and observed values reveals that the EOF model reproduces the observation with smaller root-mean-square errors and higher linear correlation coefficients. In addition, IRI discrepancy at the low latitude especially for foF2 is effectively removed by EOF model.

Modeling Chinese ionospheric layer parameters based on EOF analysis

NASA Astrophysics Data System (ADS)

Yu, You; Wan, Weixing

2016-04-01

Using 24-ionosonde observations in and around China during the 20th solar cycle, an assimilative model is constructed to map the ionospheric layer parameters (foF2, hmF2, M(3000)F2, and foE) over China based on empirical orthogonal function (EOF) analysis. First, we decompose the background maps from the International Reference Ionosphere model 2007 (IRI-07) into different EOF modes. The obtained EOF modes consist of two factors: the EOF patterns and the corresponding EOF amplitudes. These two factors individually reflect the spatial distributions (e.g., the latitudinal dependence such as the equatorial ionization anomaly structure and the longitude structure with east-west difference) and temporal variations on different time scales (e.g., solar cycle, annual, semiannual, and diurnal variations) of the layer parameters. Then, the EOF patterns and long-term observations of ionosondes are assimilated to get the observed EOF amplitudes, which are further used to construct the Chinese Ionospheric Maps (CIMs) of the layer parameters. In contrast with the IRI-07 model, the mapped CIMs successfully capture the inherent temporal and spatial variations of the ionospheric layer parameters. Finally, comparison of the modeled (EOF and IRI-07 model) and observed values reveals that the EOF model reproduces the observation with smaller root-mean-square errors and higher linear correlation co- efficients. In addition, IRI discrepancy at the low latitude especially for foF2 is effectively removed by EOF model.

A triangular prism solid and shell interactive mapping element for electromagnetic sheet metal forming process

NASA Astrophysics Data System (ADS)

Cui, Xiangyang; Li, She; Feng, Hui; Li, Guangyao

2017-05-01

In this paper, a novel triangular prism solid and shell interactive mapping element is proposed to solve the coupled magnetic-mechanical formulation in electromagnetic sheet metal forming process. A linear six-node "Triprism" element is firstly proposed for transient eddy current analysis in electromagnetic field. In present "Triprism" element, shape functions are given explicitly, and a cell-wise gradient smoothing operation is used to obtain the gradient matrices without evaluating derivatives of shape functions. In mechanical field analysis, a shear locking free triangular shell element is employed in internal force computation, and a data mapping method is developed to transfer the Lorentz force on solid into the external forces suffered by shell structure for dynamic elasto-plasticity deformation analysis. Based on the deformed triangular shell structure, a "Triprism" element generation rule is established for updated electromagnetic analysis, which means inter-transformation of meshes between the coupled fields can be performed automatically. In addition, the dynamic moving mesh is adopted for air mesh updating based on the deformation of sheet metal. A benchmark problem is carried out for confirming the accuracy of the proposed "Triprism" element in predicting flux density in electromagnetic field. Solutions of several EMF problems obtained by present work are compared with experiment results and those of traditional method, which are showing excellent performances of present interactive mapping element.

High spatial resolution mapping of folds and fractures using Unmanned Aerial Vehicle (UAV) photogrammetry

NASA Astrophysics Data System (ADS)

Cruden, A. R.; Vollgger, S.

2016-12-01

The emerging capability of UAV photogrammetry combines a simple and cost-effective method to acquire digital aerial images with advanced computer vision algorithms that compute spatial datasets from a sequence of overlapping digital photographs from various viewpoints. Depending on flight altitude and camera setup, sub-centimeter spatial resolution orthophotographs and textured dense point clouds can be achieved. Orientation data can be collected for detailed structural analysis by digitally mapping such high-resolution spatial datasets in a fraction of time and with higher fidelity compared to traditional mapping techniques. Here we describe a photogrammetric workflow applied to a structural study of folds and fractures within alternating layers of sandstone and mudstone at a coastal outcrop in SE Australia. We surveyed this location using a downward looking digital camera mounted on commercially available multi-rotor UAV that autonomously followed waypoints at a set altitude and speed to ensure sufficient image overlap, minimum motion blur and an appropriate resolution. The use of surveyed ground control points allowed us to produce a geo-referenced 3D point cloud and an orthophotograph from hundreds of digital images at a spatial resolution < 10 mm per pixel, and cm-scale location accuracy. Orientation data of brittle and ductile structures were semi-automatically extracted from these high-resolution datasets using open-source software. This resulted in an extensive and statistically relevant orientation dataset that was used to 1) interpret the progressive development of folds and faults in the region, and 2) to generate a 3D structural model that underlines the complex internal structure of the outcrop and quantifies spatial variations in fold geometries. Overall, our work highlights how UAV photogrammetry can contribute to new insights in structural analysis.

The velocity characteristics of dusty filaments in the JCMT GBS clouds

NASA Astrophysics Data System (ADS)

Buckle, J. V.; Salji, C.; Richer, J. S.

2013-07-01

Large scale, high resolution spectral and continuum imaging maps have revealed, to an unprecedented extent, the characteristics of filamentary structure in star-forming molecular clouds, and their close association with star-forming cores. The filaments are associated with the formation of dense molecular cores where star formation occurs, and recent models highlight the important relationship between filaments and star-forming clusters. Velocity-coherent filaments have been proposed as the parent structures of star forming cores in Taurus. In Serpens, accretion flows along filaments have been proposed as the continuous source of mass for the star forming cluster. An evolutionary scenario for filaments based on velocity dispersion and column density measurements has recently been proposed, which we test with large scale molecular line and dust continuum maps. The JCMT Gould Belt Survey with SCUBA-2 and HARP provides dust continuum observations at 850 and 450 micron, and 12CO/13CO/C18O J=3-2 spectral line mapping of several nearby molecular clouds, covering large angular scales at high resolution. Velocities and linewidths of optically thin species, such as C18O which traces the warm, dense gas associated with star formation, are critical for an estimate of the virial stability of filamentary structures. The data and analyses that we present provide robust statistics over a large range of starless and protostellar evolutionary states. We present the velocity characteristics of dusty filaments in Orion, probing the physics at the boundary of filamentary structure and star formation. Using C18O, we investigate the internal structure of filaments, based on fragmentation and velocity coherence in the molecular line data. Through velocity dispersion measurements, we determine whether the filamentary structures are bound, and compare results between clouds of different star formation characteristics.

Hydrology of the Helena area bedrock, west-central Montana, 1993-98; with a section on geologic setting and a generalized bedrock geologic map

USGS Publications Warehouse

Thamke, Joanna N.; Reynolds, Mitchell W.

2000-01-01

The Generalized Bedrock Geologic Map of the Helena Area, West-Central Montana (plate 1 in the report) provides an intermediate-scale overview of bedrock in the Helena area. The geologic map has been compiled at a scale of 1:100,000 from the most widely available sources of geologic map information (see index to geologic mapping on pl. 1). That information has been updated by M.W. Reynolds for this report with more recent geologic mapping and field revision of published maps. All well locations and all bedrock units penetrated during drilling have been confirmed on geologic maps at the largest scale available. Source geologic maps are all at scales larger than 1:100,000 scale. Care has been taken to ensure accurate representation of the original geology at the compilation scale. However, positional accuracy of some features might be somewhat diminished at the smaller scale of the base map when compared with the original data source. Also, line thicknesses for contacts and faults necessarily assume a greater width, relative to the real geologic feature, at the scale of the generalized map than on any original map. The map is not intended for large-scale, site-specific detailed planning. Bedrock units throughout the Helena area are generally covered by young surficial deposits such as alluvium, colluvium, glacial debris, or windblown sediment. Thickness of such deposits varies from veneers through which the underlying bedrock is clearly discernible to major thicknesses that conceal all underlying bedrock and structure. Boundaries of major accumulations of surficial deposits are attributed separately from bedrock contacts. These boundaries should not be considered precise at the map scale or at larger scales. Boundaries shown may be less accurate positionally than bedrock contacts and faults because (1) surficial deposits commonly thin to a knife edge; (2) different mappers will interpret the edge differently when drawing a boundary; or (3) the original geologic map maker was concerned principally with bedrock units and structure and thus overlooked, or did not originally map as consistently, some surficial deposits. Veneers of surficial sediment, when saturated, can be local sources of recharge to underlying bedrock. Use of the generalized map to define their distribution does not substitute for site specific mapping of such deposits. Specific knowledge is needed to determine the water-bearing properties of the geologic units at and surrounding a site because the units, including the igneous and metamorphic rocks, have internal differences in stratigraphy, composition, mineralogy and grain size or crystallinity. These differences, together with structural imprints such as faults, folds, and the spacing, orientation, degree of openness of fractures, and extent and type of mineral filling in fractures and faults, all affect the ability of rocks to store and transmit water.

Tracking lava flow emplacement on the east rift zone of Kilauea, Hawai’i with synthetic aperture radar (SAR) coherence

USGS Publications Warehouse

Dietterich, Hannah R.; Poland, Michael P.; Schmidt, David; Cashman, Katharine V.; Sherrod, David R.; Espinosa, Arkin Tapia

2012-01-01

Lava flow mapping is both an essential component of volcano monitoring and a valuable tool for investigating lava flow behavior. Although maps are traditionally created through field surveys, remote sensing allows an extraordinary view of active lava flows while avoiding the difficulties of mapping on location. Synthetic aperture radar (SAR) imagery, in particular, can detect changes in a flow field by comparing two images collected at different times with SAR coherence. New lava flows radically alter the scattering properties of the surface, making the radar signal decorrelated in SAR coherence images. We describe a new technique, SAR Coherence Mapping (SCM), to map lava flows automatically from coherence images independent of look angle or satellite path. We use this approach to map lava flow emplacement during the Pu‘u ‘Ō‘ō-Kupaianaha eruption at Kīlauea, Hawai‘i. The resulting flow maps correspond well with field mapping and better resolve the internal structure of surface flows, as well as the locations of active flow paths. However, the SCM technique is only moderately successful at mapping flows that enter vegetation, which is also often decorrelated between successive SAR images. Along with measurements of planform morphology, we are able to show that the length of time a flow stays decorrelated after initial emplacement is linearly related to the flow thickness. Finally, we use interferograms obtained after flow surfaces become correlated to show that persistent decorrelation is caused by post-emplacement flow subsidence.

Tracking lava flow emplacement on the east rift zone of Kīlauea, Hawai‘i, with synthetic aperture radar coherence

NASA Astrophysics Data System (ADS)

Dietterich, Hannah R.; Poland, Michael P.; Schmidt, David A.; Cashman, Katharine V.; Sherrod, David R.; Espinosa, Arkin Tapia

2012-05-01

Lava flow mapping is both an essential component of volcano monitoring and a valuable tool for investigating lava flow behavior. Although maps are traditionally created through field surveys, remote sensing allows an extraordinary view of active lava flows while avoiding the difficulties of mapping on location. Synthetic aperture radar (SAR) imagery, in particular, can detect changes in a flow field by comparing two images collected at different times with SAR coherence. New lava flows radically alter the scattering properties of the surface, making the radar signal decorrelated in SAR coherence images. We describe a new technique, SAR Coherence Mapping (SCM), to map lava flows automatically from coherence images independent of look angle or satellite path. We use this approach to map lava flow emplacement during the Pu`u `Ō`ō-Kupaianaha eruption at Kīlauea, Hawai`i. The resulting flow maps correspond well with field mapping and better resolve the internal structure of surface flows, as well as the locations of active flow paths. However, the SCM technique is only moderately successful at mapping flows that enter vegetation, which is also often decorrelated between successive SAR images. Along with measurements of planform morphology, we are able to show that the length of time a flow stays decorrelated after initial emplacement is linearly related to the flow thickness. Finally, we use interferograms obtained after flow surfaces become correlated to show that persistent decorrelation is caused by post-emplacement flow subsidence.

Sequence stratigraphy, structural style, and age of deformation of the Malaita accretionary prism (Solomon arc-Ontong Java Plateau convergent zone)

NASA Astrophysics Data System (ADS)

Phinney, Eric J.; Mann, Paul; Coffin, Millard F.; Shipley, Thomas H.

2004-10-01

Possibilities for the fate of oceanic plateaus at subduction zones range from complete subduction of the plateau beneath the arc to complete plateau-arc accretion and resulting collisional orogenesis. Deep penetration, multi-channel seismic reflection (MCS) data from the northern flank of the Solomon Islands reveal the sequence stratigraphy, structural style, and age of deformation of an accretionary prism formed during late Neogene (5-0 Ma) convergence between the ˜33-km-thick crust of the Ontong Java oceanic plateau and the ˜15-km-thick Solomon island arc. Correlation of MCS data with the satellite-derived, free-air gravity field defines the tectonic boundaries and internal structure of the 800-km-long, 140-km-wide accretionary prism. We name this prism the "Malaita accretionary prism" or "MAP" after Malaita, the largest and best-studied island exposure of the accretionary prism in the Solomon Islands. MCS data, gravity data, and stratigraphic correlations to islands and ODP sites on the Ontong Java Plateau (OJP) reveal that the offshore MAP is composed of folded and thrust faulted sedimentary rocks and upper crystalline crust offscraped from the Solomon the subducting Ontong Java Plateau (Pacific plate) and transferred to the Solomon arc. With the exception of an upper, sequence of Quaternary? island-derived terrigenous sediments, the deformed stratigraphy of the MAP is identical to that of the incoming Ontong Java Plateau in the North Solomon trench. We divide the MAP into four distinct, folded and thrust fault-bounded structural domains interpreted to have formed by diachronous, southeast-to-northwest, and highly oblique entry of the Ontong Java Plateau into a former trench now marked by the Kia-Kaipito-Korigole (KKK) left-lateral strike-slip fault zone along the suture between the Solomon arc and the MAP. The structural style within each of the four structural domains consists of a parallel series of three to four fault propagation folds formed by the seaward propagation of thrust faults roughly parallel to sub-horizontal layering in the upper crystalline part of the OJP. Thrust fault offsets, spacing between thrusts, and the amplitude of related fault propagation folds progressively decrease to the west in the youngest zone of active MAP accretion (Choiseul structural domain). Surficial faulting and folding in the most recently deformed, northwestern domain show active accretion of greater than 1 km of sedimentary rock and 6 km, or about 20%, of the upper crystalline part of the OJP. The eastern MAP (Malaita and Ulawa domains) underwent an earlier, similar style of partial plateau accretion. A pre-late Pliocene age of accretion (˜3.4 Ma) is constrained by an onshore and offshore major angular unconformity separating Pliocene reefal limestone and conglomerate from folded and faulted pelagic limestone of Cretaceous to Miocene age. The lower 80% of the Ontong Java Plateau crust beneath the MAP thrust decollement appears unfaulted and unfolded and is continuous with a southwestward-dipping subducted slab of presumably denser plateau material beneath most of the MAP, and is traceable to depths >200 km in the mantle beneath the Solomon Islands.

Seafloor 2030 - Building a Global Ocean Map through International Collaboration

NASA Astrophysics Data System (ADS)

Ferrini, V. L.; Wigley, R. A.; Falconer, R. K. H.; Jakobsson, M.; Allen, G.; Mayer, L. A.; Schmitt, T.; Rovere, M.; Weatherall, P.; Marks, K. M.

2016-12-01

With more than 85% of the ocean floor unmapped, a huge proportion of our planet remains unexplored. Creating a comprehensive map of seafloor bathymetry remains a true global challenge that can only be accomplished through collaboration and partnership between governments, industry, academia, research organizations and non-government organizations. The objective of Seafloor 2030 is to comprehensively map the global ocean floor to resolutions that enable exploration and improved understanding of ocean processes, while informing maritime policy and supporting the management of natural marine resources for a sustainable Blue Economy. Seafloor 2030 is the outcome of the Forum for Future of Ocean Floor Mapping held in Monaco in June 2016, which was held under the auspices of GEBCO and the Nippon Foundation of Japan. GEBCO is the only international organization mandated to map the global ocean floor and is guided by the International Hydrographic Organization (IHO) and the Intergovernmental Oceanographic Commission of UNESCO. The task of completely mapping the ocean floor will require new global coordination to ensure that both existing data are identified and that new mapping efforts are coordinated to help efficiently "map the gaps." Fundamental to achieving Seafloor 2030 will be greater access to data, tools and technology, particularly for developing and coastal nations. This includes bathymetric post-processing and analysis software, database technology, computing infrastructure and gridding techniques as well as the latest developments in seafloor mapping methods and emerging crowd-sourced bathymetry initiatives. The key to achieving this global bathymetric map is capacity building and education - including greater coordination between scientific research and industry and the effective engagement of international organizations such as the United Nations.

Eastern Denali Fault surface trace map, eastern Alaska and Yukon, Canada

USGS Publications Warehouse

Bender, Adrian M.; Haeussler, Peter J.

2017-05-04

We map the 385-kilometer (km) long surface trace of the right-lateral, strike-slip Denali Fault between the Totschunda-Denali Fault intersection in Alaska, United States and the village of Haines Junction, Yukon, Canada. In Alaska, digital elevation models based on light detection and ranging and interferometric synthetic aperture radar data enabled our fault mapping at scales of 1:2,000 and 1:10,000, respectively. Lacking such resources in Yukon, we developed new structure-from-motion digital photogrammetry products from legacy aerial photos to map the fault surface trace at a scale of 1:10,000 east of the international border. The section of the fault that we map, referred to as the Eastern Denali Fault, did not rupture during the 2002 Denali Fault earthquake (moment magnitude 7.9). Seismologic, geodetic, and geomorphic evidence, along with a paleoseismic record of past ground-rupturing earthquakes, demonstrate Holocene and contemporary activity on the fault, however. This map of the Eastern Denali Fault surface trace complements other data sets by providing an openly accessible digital interpretation of the location, length, and continuity of the fault’s surface trace based on the accompanying digital topography dataset. Additionally, the digitized fault trace may provide geometric constraints useful for modeling earthquake scenarios and related seismic hazard.

Impact of cell size on inventory and mapping errors in a cellular geographic information system

NASA Technical Reports Server (NTRS)

Wehde, M. E. (Principal Investigator)

1979-01-01

The author has identified the following significant results. The effect of grid position was found insignificant for maps but highly significant for isolated mapping units. A modelable relationship between mapping error and cell size was observed for the map segment analyzed. Map data structure was also analyzed with an interboundary distance distribution approach. Map data structure and the impact of cell size on that structure were observed. The existence of a model allowing prediction of mapping error based on map structure was hypothesized and two generations of models were tested under simplifying assumptions.

Democratizing LGBTQ History Online: Digitizing Public History in "U.S. Homophile Internationalism".

PubMed

de Szegheo Lang, Tamara

2017-01-01

This article argues that the online archive and exhibit "U.S. Homophile Internationalism" effectively contributes to the democratizing effects that digital archives and online initiatives are having on the practice of history. "U.S. Homophile Internationalism" is an online archive of over 800 digitized articles, letters, advertisements, and other materials from the U.S. homophile press that reference six non-U.S. regions of the world. It also provides visitors with introductory regional essays, annotated bibliographies, and an interactive map feature. This essay weaves "U.S. Homophile Internationalism" into the debates in community-run LGBTQ archives regarding the digitization of archival materials and the possibilities presented by digital public history. In doing so, it outlines the structure and content of "U.S. Homophile Internationalism," highlighting how it increases the public accessibility of primary sources, encourages historical research on regions of the world that have not been adequately represented in LGBTQ history writing, and creates interactive components to support public engagements with the Web site.

Variability of Protein Structure Models from Electron Microscopy.

PubMed

Monroe, Lyman; Terashi, Genki; Kihara, Daisuke

2017-04-04

An increasing number of biomolecular structures are solved by electron microscopy (EM). However, the quality of structure models determined from EM maps vary substantially. To understand to what extent structure models are supported by information embedded in EM maps, we used two computational structure refinement methods to examine how much structures can be refined using a dataset of 49 maps with accompanying structure models. The extent of structure modification as well as the disagreement between refinement models produced by the two computational methods scaled inversely with the global and the local map resolutions. A general quantitative estimation of deviations of structures for particular map resolutions are provided. Our results indicate that the observed discrepancy between the deposited map and the refined models is due to the lack of structural information present in EM maps and thus these annotations must be used with caution for further applications. Copyright © 2017 Elsevier Ltd. All rights reserved.

International News Flows in the Post-Cold War World: Mapping the News and the News Producers.

ERIC Educational Resources Information Center

Sreberny-Mohammadi, Annabelle

1995-01-01

Reviews the global political environment, major global news providers, and technologies of global news production. Argues for a multinational comparative mapping of international news representation in the 1990s. Outlines a major international venture to update and elaborate the 1979 UNESCO/IAMCR study of foreign news in the media of 29 countries,…

Singapore Genome Variation Project: a haplotype map of three Southeast Asian populations.

PubMed

Teo, Yik-Ying; Sim, Xueling; Ong, Rick T H; Tan, Adrian K S; Chen, Jieming; Tantoso, Erwin; Small, Kerrin S; Ku, Chee-Seng; Lee, Edmund J D; Seielstad, Mark; Chia, Kee-Seng

2009-11-01

The Singapore Genome Variation Project (SGVP) provides a publicly available resource of 1.6 million single nucleotide polymorphisms (SNPs) genotyped in 268 individuals from the Chinese, Malay, and Indian population groups in Southeast Asia. This online database catalogs information and summaries on genotype and phased haplotype data, including allele frequencies, assessment of linkage disequilibrium (LD), and recombination rates in a format similar to the International HapMap Project. Here, we introduce this resource and describe the analysis of human genomic variation upon agglomerating data from the HapMap and the Human Genome Diversity Project, providing useful insights into the population structure of the three major population groups in Asia. In addition, this resource also surveyed across the genome for variation in regional patterns of LD between the HapMap and SGVP populations, and for signatures of positive natural selection using two well-established metrics: iHS and XP-EHH. The raw and processed genetic data, together with all population genetic summaries, are publicly available for download and browsing through a web browser modeled with the Generic Genome Browser.

Singapore Genome Variation Project: A haplotype map of three Southeast Asian populations

PubMed Central

Teo, Yik-Ying; Sim, Xueling; Ong, Rick T.H.; Tan, Adrian K.S.; Chen, Jieming; Tantoso, Erwin; Small, Kerrin S.; Ku, Chee-Seng; Lee, Edmund J.D.; Seielstad, Mark; Chia, Kee-Seng

2009-01-01

The Singapore Genome Variation Project (SGVP) provides a publicly available resource of 1.6 million single nucleotide polymorphisms (SNPs) genotyped in 268 individuals from the Chinese, Malay, and Indian population groups in Southeast Asia. This online database catalogs information and summaries on genotype and phased haplotype data, including allele frequencies, assessment of linkage disequilibrium (LD), and recombination rates in a format similar to the International HapMap Project. Here, we introduce this resource and describe the analysis of human genomic variation upon agglomerating data from the HapMap and the Human Genome Diversity Project, providing useful insights into the population structure of the three major population groups in Asia. In addition, this resource also surveyed across the genome for variation in regional patterns of LD between the HapMap and SGVP populations, and for signatures of positive natural selection using two well-established metrics: iHS and XP-EHH. The raw and processed genetic data, together with all population genetic summaries, are publicly available for download and browsing through a web browser modeled with the Generic Genome Browser. PMID:19700652

Diagnostic Reasoning across the Medical Education Continuum.

PubMed

Smith, C Scott; Hill, William; Francovich, Chris; Morris, Magdalena; Robbins, Bruce; Robins, Lynne; Turner, Andrew

2014-07-15

We aimed to study linguistic and non-linguistic elements of diagnostic reasoning across the continuum of medical education. We performed semi-structured interviews of premedical students, first year medical students, third year medical students, second year internal medicine residents, and experienced faculty (ten each) as they diagnosed three common causes of dyspnea. A second observer recorded emotional tone. All interviews were digitally recorded and blinded transcripts were created. Propositional analysis and concept mapping were performed. Grounded theory was used to identify salient categories and transcripts were scored with these categories. Transcripts were then unblinded. Systematic differences in propositional structure, number of concept connections, distribution of grounded theory categories, episodic and semantic memories, and emotional tone were identified. Summary concept maps were created and grounded theory concepts were explored for each learning level. We identified three major findings: (1) The "apprentice effect" in novices (high stress and low narrative competence); (2) logistic concept growth in intermediates; and (3) a cognitive state transition (between analytical and intuitive approaches) in experts. These findings warrant further study and comparison.

Functional interactions at the interface between voltage-sensing and pore domains in the Shaker K(v) channel.

PubMed

Soler-Llavina, Gilberto J; Chang, Tsg-Hui; Swartz, Kenton J

2006-11-22

Voltage-activated potassium (K(v)) channels contain a central pore domain that is partially surrounded by four voltage-sensing domains. Recent X-ray structures suggest that the two domains lack extensive protein-protein contacts within presumed transmembrane regions, but whether this is the case for functional channels embedded in lipid membranes remains to be tested. We investigated domain interactions in the Shaker K(v) channel by systematically mutating the pore domain and assessing tolerance by examining channel maturation, S4 gating charge movement, and channel opening. When mapped onto the X-ray structure of the K(v)1.2 channel the large number of permissive mutations support the notion of relatively independent domains, consistent with crystallographic studies. Inspection of the maps also identifies portions of the interface where residues are sensitive to mutation, an external cluster where mutations hinder voltage sensor activation, and an internal cluster where domain interactions between S4 and S5 helices from adjacent subunits appear crucial for the concerted opening transition.

Mapping Vesta Mid-Latitude Quadrangle V-12EW: Mapping the Edge of the South Polar Structure

NASA Astrophysics Data System (ADS)

Hoogenboom, T.; Schenk, P.; Williams, D. A.; Hiesinger, H.; Garry, W. B.; Yingst, R.; Buczkowski, D.; McCord, T. B.; Jaumann, R.; Pieters, C. M.; Gaskell, R. W.; Neukum, G.; Schmedemann, N.; Marchi, S.; Nathues, A.; Le Corre, L.; Roatsch, T.; Preusker, F.; White, O. L.; DeSanctis, C.; Filacchione, G.; Raymond, C. A.; Russell, C. T.

2011-12-01

NASA's Dawn spacecraft arrived at the asteroid 4Vesta on July 15, 2011, and is now collecting imaging, spectroscopic, and elemental abundance data during its one-year orbital mission. As part of the geological analysis of the surface, a series of 15 quadrangle maps are being produced based on Framing Camera images (FC: spatial resolution: ~65 m/pixel) along with Visible & Infrared Spectrometer data (VIR: spatial resolution: ~180 m/pixel) obtained during the High-Altitude Mapping Orbit (HAMO). This poster presentation concentrates on our geologic analysis and mapping of quadrangle V-12EW. This quadrangle is dominated by the arcuate edge of the large 460+ km diameter south polar topographic feature first observed by HST (Thomas et al., 1997). Sparsely cratered, the portion of this feature covered in V-12EW is characterized by arcuate ridges and troughs forming a generalized arcuate pattern. Mapping of this terrain and the transition to areas to the north will be used to test whether this feature has an impact or other (e.g., internal) origin. We are also using FC stereo and VIR images to assess whether their are any compositional differences between this terrain and areas further to the north, and image data to evaluate the distribution and age of young impact craters within the map area. The authors acknowledge the support of the Dawn Science, Instrument and Operations Teams.

Creating affordable Internet map server applications for regional scale applications.

PubMed

Lembo, Arthur J; Wagenet, Linda P; Schusler, Tania; DeGloria, Stephen D

2007-12-01

This paper presents an overview and process for developing an Internet Map Server (IMS) application for a local volunteer watershed group using an Internal Internet Map Server (IIMS) strategy. The paper illustrates that modern GIS architectures utilizing an internal Internet map server coupled with a spatial SQL command language allow for rapid development of IMS applications. The implication of this approach means that powerful IMS applications can be rapidly and affordably developed for volunteer organizations that lack significant funds or a full time information technology staff.

Geologic and Mineral Resource Map of Afghanistan

USGS Publications Warehouse

Doebrich, Jeff L.; Wahl, Ronald R.; With Contributions by Ludington, Stephen D.; Chirico, Peter G.; Wandrey, Craig J.; Bohannon, Robert G.; Orris, Greta J.; Bliss, James D.; Wasy, Abdul; Younusi, Mohammad O.

2006-01-01

Data Summary The geologic and mineral resource information shown on this map is derived from digitization of the original data from Abdullah and Chmyriov (1977) and Abdullah and others (1977). The U.S. Geological Survey (USGS) has made no attempt to modify original geologic map-unit boundaries and faults as presented in Abdullah and Chmyriov (1977); however, modifications to map-unit symbology, and minor modifications to map-unit descriptions, have been made to clarify lithostratigraphy and to modernize terminology. Labeling of map units has not been attempted where they are small or narrow, in order to maintain legibility and to preserve the map's utility in illustrating regional geologic and structural relations. Users are encouraged to refer to the series of USGS/AGS (Afghan Geological Survey) 1:250,000-scale geologic quadrangle maps of Afghanistan that are being released concurrently as open-file reports. The classification of mineral deposit types is based on the authors' interpretation of existing descriptive information (Abdullah and others, 1977; Bowersox and Chamberlin, 1995; Orris and Bliss, 2002) and on limited field investigations by the authors. Deposit-type nomenclature used for nonfuel minerals is modified from published USGS deposit-model classifications, as compiled in Stoeser and Heran (2000). New petroleum localities are based on research of archival data by the authors. The shaded-relief base is derived from Shuttle Radar Topography Mission (SRTM) digital elevation model (DEM) data having 85-meter resolution. Gaps in the original SRTM DEM dataset were filled with data digitized from contours on 1:200,000-scale Soviet General Staff Sheets (1978-1997). The marginal extent of geologic units corresponds to the position of the international boundary as defined by Abdullah and Chmyriov (1977), and the international boundary as shown on this map was acquired from the Afghanistan Information Management Service (AIMS) Web site (http://www.aims.org.af) in September 2005. Non-coincidence of these boundaries is due to differences in the respective data sources and to inexact registration of the geologic data to the DEM base. Province boundaries, province capital locations, and political names were also acquired from the AIMS Web site in September 2005. The AIMS data were originally derived from maps produced by the Afghanistan Geodesy and Cartography Head Office (AGCHO). Version 2 differs from Version 1 in that (1) map units are colored according to the color scheme of the Commission for the Geological Map of the World (CGMW) (http://www.ccgm.org), (2) the minerals database has been updated, and (3) all data presented on the map are also available in GIS format.

Velocity and Structure Estimation of a Moving Object Using a Moving Monocular Camera

DTIC Science & Technology

2006-01-01

map the Euclidean position of static landmarks or visual features in the environment . Recent applications of this technique include aerial...From Motion in a Piecewise Planar Environment ,” International Journal of Pattern Recognition and Artificial Intelligence, Vol. 2, No. 3, pp. 485-508...1988. [9] J. M. Ferryman, S. J. Maybank , and A. D. Worrall, “Visual Surveil- lance for Moving Vehicles,” Intl. Journal of Computer Vision, Vol. 37, No

Climate Change Impact on the Southeastern Europe Security Environment and the Increasing Role of the Bulgarian Army as the World Warms

DTIC Science & Technology

2016-06-10

expected risks posed by climate change will reshape the Bulgarian Army structure and capabilities if the Army is to develop the proficiency to face...thousands of local timber based manufacturers and small scaled industries, and a few big and international oriented pulp, paper and board producers...prevention, social timber supply, etc.55 54 Union of Concerned Scientists, “Climate Hot Map,” accessed 20

Looking Into and Through the Ross Ice Shelf - ROSETTA-ICE

NASA Astrophysics Data System (ADS)

Bell, R. E.

2015-12-01

Our current understanding of the structure and stability of the Ross Ice Shelf is based on satellite studies of the ice surface and the 1970's RIGGS program. The study of the flowlines evident in the MODIS imagery combined with surface geophysics has revealed a complex history with ice streams Mercer, Whillans and Kamb changing velocity over the past 1000 years. Here, we present preliminary IcePod and IceBridge radar data acquired in December 2014 and November 2013 across the Ross Ice Shelf that show clearly, for the first time, the structure of the ice shelf and provide insights into ice-ocean interaction. The three major layers of the ice shelf are (1) the continental meteoric ice layer), ice formed on the grounded ice sheet that entered the ice shelf where ice streams and outlet glaciers crossed the grounding line (2) the locally accumulating meteoric ice layer, ice and snow that forms from snowfall on the floating ice shelf and (3) a basal marine ice layer. The locally accumulating meteoric ice layer contains well-defined internal layers that are generally parallel to the ice surface and thickens away from the grounding line and reaches a maximum thickness of 220m along the line crossing Roosevelt Island. The continental meteoric layer is located below a broad irregular internal reflector, and is characterized by irregular internal layers. These internal layers are often folded, likely a result of deformation as the ice flowed across the grounding line. The basal marine ice layer, up to 50m thick, is best resolved in locations where basal crevasses are present, and appears to thicken along the flow at rates of decimeters per year. Each individual flowband of the ice shelf contains layers that are distinct in their structure. For example, the thickness of the locally accumulated layer is a function of both the time since crossing the grounding line and the thickness of the incoming ice. Features in the meteoric ice, such as distinct folds, can be traced between the two IceBridge lines located 47 km apart. The ROSETTA-ICE program will begin a systematic mapping of the Ross Ice Shelf and sub-ice topography using the IcePod system beginning in 2015. Together the new gravity-derived bathymetry and the mapping of the ice shelf structure will provide key insights into the stability of the ice shelf.

Integration of magnetometric, gpr and geoelectric measurements applied to the study of the new Viggiano archaeological site (Southern Italy).

NASA Astrophysics Data System (ADS)

Rizzo, E.; Chianese, D.; Lapenna, V.; Piscitelli, S.

2003-04-01

In the frame of a collaboration with the Archaeological Superintendence of the Basilicata Region (Southern Italy), the Geophysical Lab of IMAA-CNR planned a multidisciplinary investigation in the archaeological site of Viggiano, integrating magnetic mapping, Ground Penetrating Radar profiling and 3D electrical resistivity imaging. The archaeological site, located in Agri Valley (Southern Italy, Basilicata), is an ancient structure developed in successive phases between IV and III century B.C. In this area during some shovel tests archaeological remnants have been identified in the western part. Successively the archaeologists hypothesized the presence of buried structures in the eastern part too, where we performed a geophysical survey. In particular, a magnetic map by means of a caesium vapour magnetometer G-858 GEOMETRICS has been carried to find the external perimeter; more than 50 Georadar profiles using SIR 2000 instrument have been performed to delineate the internal buried structures and the electrical resistivity method has been applied to estimate the depth of buried structures. According to the archaeological hypothesis significant wall structures have been identified in the eastern part. In conclusion, the integration of different geophysical techniques allows us to obtain very intriguing information about the shape, the dimension and the depth of the oriental buried wall structures giving a contribute to better develop a new hypothesis about the history of the archaeological site of Viggiano.

Complex deformation associated with anhydrite layers in the Tromsø Basin, SW Barents Sea.

NASA Astrophysics Data System (ADS)

Marfo, George; Olakunle Omosanya, Kamaldeen; Johansen, Ståle Emil; Zervas, Ioannis

2017-04-01

Internal and external deformation associated with salt structures is of prime interest due to their economic importance as hydrocarbon seals, reservoirs, repositories for chemical waste and their implication on drilling. Salt structures are often associated with anhydrites, which may 'cap' or are enclosed within the allochthonous salt structures. Despite their economic importance, the internal and external structures of evaporites remain poorly studied from field and seismic data due to the sparse outcrops of evaporites and poor seismic imaging. The zero-phased, normal polarity, high resolution multiple 2D seismic data, in combination with detailed interpretation of wireline logs provide an excellent study into the salt structures, and offers a good opportunity to investigate the dynamics, geometries and mechanisms driving deformation of internal and external salt layers associated with the Late Carboniferous to Early Permian Salt structures in the Tromsø Basin. The methods include seismic interpretation and the application of multiple seismic attributes to map stratigraphic units and discontinuities. Our results show that the anhydrite layers are marked by high amplitude reflections at the crests and flanks or fully enclosed within the salt diapirs. Crestal and lateral anhydrite caprocks represent external salt structures whilst the entrained anhydrites or stringers are intrasalt structures. Anhydrite caprocks generally show structural styles such as faults and large-scale folds which are harmonic to the top salt structure. In contrast, anhydrite stringers show folds of varying scale, which are harmonic to disharmonic to the top salt structure. Boudins and steeply dipping stringer fragments are also interpreted within the stringers. Caprock deformation is attributed to salt upwelling. Folding and boudinaging of originally horizontal and continuous stringer layers formed from a multiphase superimposed sequence of ductile and brittle deformation in response to complex multi-dimensional salt flow. Internal salt flow involves radial and tangential compression, which leads to dominant fold structures near the margins. Boudins on the lower flanks of the diapir formed due radial extension. Our study further demonstrates that differential geometries exhibited by the different anhydrite groups imply that the mechanisms deforming internal and external salt structures are different. The results from this study are comparable to observations from salt mines, field exposures, scaled physical and numerical models.

Using Concept Maps to Monitor Knowledge Structure Changes in a Science Classroom

NASA Astrophysics Data System (ADS)

Cook, Leah J.

The aim of this research is to determine what differences may exist in students' structural knowledge while using a variety of concept mapping assessments. A concept map can be used as an assessment which connects concepts in a knowledge domain. A single assessment may not be powerful enough to establish how students' new knowledge relates to prior knowledge. More research is needed to establish how various aspects of the concept mapping task influence the output of map creation by students. Using multiple concept maps and pre-instruction and post-instruction VNOS instruments during a 16-week semester, this study was designed to investigate the impact of concept map training and the impact of assessment design on the created maps. Also, this study was designed to determine what differences can be observed between expert and novice maps and if similarities and differences exist between concept maps and an open-ended assessment. Participants created individual maps and the maps were analyzed for structural complexity, overall structure, and content. The concept maps were then compared by their timing, design, and scores. The results indicate that concept mapping training does significantly impact the shape and structure complexity of the map created by students. Additionally, these data support that students should be frequently reminded of appropriate concept mapping skills and opportunities so that good mapping skills will be utilized. Changing the assessment design does appear to be able to impact the overall structure and complexity of created maps, while narrowing the content focus of the map does not necessarily restrict the overall structure or the complexity. Furthermore, significant differences in structural complexity were observed between novice and expert mappers. The fluctuations of NOS concepts identified in student created maps may suggest why some students were still confused or had incorrect conceptions of NOS, despite explicit and reflective instruction throughout the semester.

Geophysical imaging of karst features in Missouri

NASA Astrophysics Data System (ADS)

Obi, Jeremiah Chukwunonso

Automated electrical resistivity tomography (ERT) supported with multichannel analysis of surface waves (MASW) and boring data were used to map karst related features in Missouri in order to understand karst processes better in Missouri. Previous works on karst in Missouri were mostly surficial mapping of bedrock outcrops and joints, which are not enough to define the internal structure of karst system, since most critical processes in karst occur underground. To understand these processes better, the density, placement and pattern of karst related features like solution-widened joints and voids, as well as top of bedrock were mapped. In the course of the study, six study sites were visited in Missouri. The sites were in Nixa, Gasconade River Bridge in Lebanon, Battlefield, Aurora, Protem and Richland. The case studies reflect to a large extent some of the problems inherent in karst terrain, ranging from environmental problems to structural problems especially sinkhole collapses. The result of the study showed that karst in Missouri is mostly formed as a result of piping of sediments through solution-widened joints, with a pattern showing that the joints/fractures are mostly filled with moist clay-sized materials of low resistivity values. The highest density of mapped solution-widened joints was one in every one hundred and fifty feet, and these areas are where intense dissolution is taking place, and bedrock pervasively fractured. The study also showed that interpreted solution-widened joints trend in different directions, and often times conform with known structural lineaments in the area. About 40% of sinkhole collapses in the study areas are anthropogenic. Karst in Missouri varies, and can be classified as a combination of kI (juvenile), kIII (mature) and kIV (complex) karsts.

In situ synchrotron X-ray diffraction study on epitaxial-growth dynamics of III–V semiconductors

NASA Astrophysics Data System (ADS)

Takahasi, Masamitu

2018-05-01

The application of in situ synchrotron X-ray diffraction (XRD) to the molecular-beam epitaxial (MBE) growth of III–V semiconductors is overviewed along with backgrounds of the diffraction theory and instrumentation. X-rays are sensitive not only to the surface of growing films but also to buried interfacial structures because of their large penetration depth. Moreover, a spatial coherence length up to µm order makes X-rays widely applicable to the characterization of low-dimensional structures, such as quantum dots and wires. In situ XRD studies during growth were performed using an X-ray diffractometer, which was combined with an MBE chamber. X-ray reciprocal space mapping at a speed matching a typical growth rate was achieved using intense X-rays available from a synchrotron light source and an area detector. The importance of measuring the three-dimensional distribution of XRD intensity in a reciprocal space map is demonstrated for the MBE growth of two-, one-, and zero-dimensional structures. A large amount of information about the growth process of two-dimensional InGaAs/GaAs(001) epitaxial films has been provided by three-dimensional X-ray reciprocal mappings, including the anisotropic strain relaxation, the compositional inhomogeneity, and the evolution of surface and interfacial roughness. For one-dimensional GaAs nanowires grown in a Au-catalyzed vapor-liquid–solid mode, the relationship between the diameter of the nanowires and the formation of polytypes has been suggested on the basis of in situ XRD measurements. In situ three-dimensional X-ray reciprocal space mapping is also shown to be useful for determining the lateral and vertical sizes of self-assembled InAs/GaAs(001) quantum dots as well as their internal strain distributions during growth.

Risk-targeted versus current seismic design maps for the conterminous United States

USGS Publications Warehouse

Luco, Nicolas; Ellingwood, Bruce R.; Hamburger, Ronald O.; Hooper, John D.; Kimball, Jeffrey K.; Kircher, Charles A.

2007-01-01

The probabilistic portions of the seismic design maps in the NEHRP Provisions (FEMA, 2003/2000/1997), and in the International Building Code (ICC, 2006/2003/2000) and ASCE Standard 7-05 (ASCE, 2005a), provide ground motion values from the USGS that have a 2% probability of being exceeded in 50 years. Under the assumption that the capacity against collapse of structures designed for these "uniformhazard" ground motions is equal to, without uncertainty, the corresponding mapped value at the location of the structure, the probability of its collapse in 50 years is also uniform. This is not the case however, when it is recognized that there is, in fact, uncertainty in the structural capacity. In that case, siteto-site variability in the shape of ground motion hazard curves results in a lack of uniformity. This paper explains the basis for proposed adjustments to the uniform-hazard portions of the seismic design maps currently in the NEHRP Provisions that result in uniform estimated collapse probability. For seismic design of nuclear facilities, analogous but specialized adjustments have recently been defined in ASCE Standard 43-05 (ASCE, 2005b). In support of the 2009 update of the NEHRP Provisions currently being conducted by the Building Seismic Safety Council (BSSC), herein we provide examples of the adjusted ground motions for a selected target collapse probability (or target risk). Relative to the probabilistic MCE ground motions currently in the NEHRP Provisions, the risk-targeted ground motions for design are smaller (by as much as about 30%) in the New Madrid Seismic Zone, near Charleston, South Carolina, and in the coastal region of Oregon, with relatively little (<15%) change almost everywhere else in the conterminous U.S.

Report of the Second International Workshop on Human Chromosome 5 Mapping

DOE Office of Scientific and Technical Information (OSTI.GOV)

Westbrook, C.A.; Neuman, W.L.; McPherson, J.

This report describes the accomplishments of the Second International Workshop on Human Chromosome 5 as was held May 11--13,1992 at the University of Chicago. Included in the report are abstract of individual presentations and a consensus map of the chromosome.

Computational methods for constructing protein structure models from 3D electron microscopy maps.

PubMed

Esquivel-Rodríguez, Juan; Kihara, Daisuke

2013-10-01

Protein structure determination by cryo-electron microscopy (EM) has made significant progress in the past decades. Resolutions of EM maps have been improving as evidenced by recently reported structures that are solved at high resolutions close to 3Å. Computational methods play a key role in interpreting EM data. Among many computational procedures applied to an EM map to obtain protein structure information, in this article we focus on reviewing computational methods that model protein three-dimensional (3D) structures from a 3D EM density map that is constructed from two-dimensional (2D) maps. The computational methods we discuss range from de novo methods, which identify structural elements in an EM map, to structure fitting methods, where known high resolution structures are fit into a low-resolution EM map. A list of available computational tools is also provided. Copyright © 2013 Elsevier Inc. All rights reserved.

Combining geomorphological mapping and near surface geophysics (GPR and ERT) to study piping systems

NASA Astrophysics Data System (ADS)

Bernatek-Jakiel, Anita; Kondracka, Marta

2016-12-01

This paper aims to provide a more comprehensive characterization of piping systems in mountainous areas under a temperate climate using geomorphological mapping and geophysical methods (electrical resistivity tomography - ERT and ground penetrating radar - GPR). The significance of piping in gully formation and hillslope hydrology has been discussed for many years, and most of the studies are based on surface investigations. However, it seems that most surface investigations underestimate this subsurface process. Therefore, our purpose was to estimate the scale of piping activity based on both surface and subsurface investigations. We used geophysical methods to detect the boundary of lateral water movement fostering pipe development and recognize the internal structure of the underlying materials. The survey was carried out in the Bereźnica Wyżna catchment, in the Bieszczady Mountains. (Eastern Carpathians, Poland), where pipes develop in Cambisols at a mean depth of about 0.7-0.8 m. The geophysical techniques that were used are shown to be successful in identifying pipes. GPR data suggest that the density of piping systems is much larger than that detectible from surface observations alone. Pipe length can be > 6.5-9.2% (maximum = 49%) higher than what surface mapping suggests. Thus, the significance of piping in hillslope hydrology and gully formation can be greater than previously assumed. These results also draw attention to the scale of piping activity in the Carpathians, where this process has been neglected for many years. The ERT profiles reveal areas affected by piping as places of higher resistivity values, which are an effect of a higher content of air-filled pores (due to higher soil porosity, intense biological activity, and well-developed soil structure). In addition, the ERT profiles show that the pipes in the study area develop at the soil-bedrock interface, probably above the layers of shales or mudstones which create a water restrictive layer. Our results illustrate the suitability and limitations of GPR and ERT to study soil piping. In general, geophysical surveying is useful for gathering more information on pipe density, potential pipe detection, and recognition of the internal structure of materials underlying the pipes. However, the interpretation of radargrams and ERT profiles should be always accompanied by detailed terrain mapping due to potential disturbances affecting geophysical profiles.

Development of Maximum Considered Earthquake Ground Motion Maps

USGS Publications Warehouse

Leyendecker, E.V.; Hunt, R.J.; Frankel, A.D.; Rukstales, K.S.

2000-01-01

The 1997 NEHRP Recommended Provisions for Seismic Regulations for New Buildings use a design procedure that is based on spectral response acceleration rather than the traditional peak ground acceleration, peak ground velocity, or zone factors. The spectral response accelerations are obtained from maps prepared following the recommendations of the Building Seismic Safety Council's (BSSC) Seismic Design Procedures Group (SDPG). The SDPG-recommended maps, the Maximum Considered Earthquake (MCE) Ground Motion Maps, are based on the U.S. Geological Survey (USGS) probabilistic hazard maps with additional modifications incorporating deterministic ground motions in selected areas and the application of engineering judgement. The MCE ground motion maps included with the 1997 NEHRP Provisions also serve as the basis for the ground motion maps used in the seismic design portions of the 2000 International Building Code and the 2000 International Residential Code. Additionally the design maps prepared for the 1997 NEHRP Provisions, combined with selected USGS probabilistic maps, are used with the 1997 NEHRP Guidelines for the Seismic Rehabilitation of Buildings.

The International Permafrost Association: current initiatives for cryospheric research

NASA Astrophysics Data System (ADS)

Schollaen, Karina; Lewkowicz, Antoni G.; Christiansen, Hanne H.; Romanovsky, Vladimir E.; Lantuit, Hugues; Schrott, Lothar; Sergeev, Dimitry; Wei, Ma

2015-04-01

The International Permafrost Association (IPA), founded in 1983, has as its objectives to foster the dissemination of knowledge concerning permafrost and to promote cooperation among persons and national or international organizations engaged in scientific investigation and engineering work on permafrost. The IPA's primary responsibilities are convening International Permafrost Conferences, undertaking special projects such as preparing databases, maps, bibliographies, and glossaries, and coordinating international field programs and networks. Membership is through adhering national or multinational organizations or as individuals in countries where no Adhering Body exists. The IPA is governed by its Executive Committee and a Council consisting of representatives from 26 Adhering Bodies having interests in some aspect of theoretical, basic and applied frozen ground research, including permafrost, seasonal frost, artificial freezing and periglacial phenomena. This presentation details the IPA core products, achievements and activities as well as current projects in cryospheric research. One of the most important core products is the circumpolar permafrost map. The IPA also fosters and supports the activities of the Global Terrestrial Network on Permafrost (GTN-P) sponsored by the Global Terrestrial Observing System, GTOS, and the Global Climate Observing System, GCOS, whose long-term goal is to obtain a comprehensive view of the spatial structure, trends, and variability of changes in the active layer thickness and permafrost temperature. A further important initiative of the IPA are the biannually competitively-funded Action Groups which work towards the production of well-defined products over a period of two years. Current IPA Action Groups are working on highly topical and interdisciplinary issues, such as the development of a regional Palaeo-map of Permafrost in Eurasia, the integration of multidisciplinary knowledge about the use of thermokarst and permafrost landscapes, and defining permafrost research priorities - a roadmap for the future. The latter project is a joint effort with the Climate and Cryosphere initiative (CliC) and a contribution to the upcoming International Conference on Arctic Research Planning III (ICARP III). The product stemming from the effort will consist of a journal publication listing permafrost research priorities and putting them into context. In all of these activities, the IPA emphasizes the involvement of young researchers (especially through the Permafrost Young Researchers Network and APECS) as well as its collaboration with international partner organizations such as IASC, SCAR, CliC, IACS, IUGS and WMO.

Toward a periodic table of personality: Mapping personality scales between the five-factor model and the circumplex model.

PubMed

Woods, Stephen A; Anderson, Neil R

2016-04-01

In this study, we examine the structures of 10 personality inventories (PIs) widely used for personnel assessment by mapping the scales of PIs to the lexical Big Five circumplex model resulting in a Periodic Table of Personality. Correlations between 273 scales from 10 internationally popular PIs with independent markers of the lexical Big Five are reported, based on data from samples in 2 countries (United Kingdom, N = 286; United States, N = 1,046), permitting us to map these scales onto the Abridged Big Five Dimensional Circumplex model (Hofstee, de Raad, & Goldberg, 1992). Emerging from our findings we propose a common facet framework derived from the scales of the PIs in our study. These results provide important insights into the literature on criterion-related validity of personality traits, and enable researchers and practitioners to understand how different PI scales converge and diverge and how compound PI scales may be constructed or replicated. Implications for research and practice are considered. (c) 2016 APA, all rights reserved).

Regional anatomy of the pedunculopontine nucleus: relevance for deep brain stimulation.

PubMed

Fournier-Gosselin, Marie-Pierre; Lipsman, Nir; Saint-Cyr, Jean A; Hamani, Clement; Lozano, Andres M

2013-09-01

The pedunculopontine nucleus (PPN) is currently being investigated as a potential deep brain stimulation target to improve gait and posture in Parkinson's disease. This review examines the complex anatomy of the PPN region and suggests a functional mapping of the surrounding nuclei and fiber tracts that may serve as a guide to a more accurate placement of electrodes while avoiding potentially adverse effects. The relationships of the PPN were examined in different human brain atlases. Schematic representations of those structures in the vicinity of the PPN were generated and correlated with their potential stimulation effects. By providing a functional map and representative schematics of the PPN region, we hope to optimize the placement of deep brain stimulation electrodes, thereby maximizing safety and clinical efficacy. © 2013 International Parkinson and Movement Disorder Society.

Digital holographic microtomography of fusion spliced optical fibers

NASA Astrophysics Data System (ADS)

Deng, Yating; Xiao, Wen; Ma, Xichao; Pan, Feng

2017-03-01

In this paper, we report three-dimensional(3D) measurement results of structural parameters of fusion spliced optical fibers using digital holographic microtomography. A holographic setup in microscopy configuration with the sample-fixed and setup-rotating scheme is established. A series of holograms is recorded from various incident angles. Then the filtered backprojection algorithm is applied to reconstruct the 3D refractive index (RI) distributions of the fusion spliced optical fibers inserted in the index-matching liquid. Experimental results exhibit the internal and external shapes of three kinds of fusion splices between different fibers, including a single-mode fiber(SMF) and a multimode fiber, an SMF and a panda polarization maintaining fiber (Panda PMF), and an SMF and a bow-tie polarization maintaining fiber (Bow-Tie PMF). With 3D maps of RI, it is intuitive to observe internal structural details of fused fibers and evaluate the splicing quality. This paper describes a powerful method for non-invasive microscopic measurement of fiber splicing. Furthermore, it provides the possibility of detecting fiber splicing loss by 3D structures.

Glimpsing Colour in a World of Black and White

DOE Office of Scientific and Technical Information (OSTI.GOV)

Michael Pennington

2012-09-01

The past 40 years have taught us that nucleons are built of constituents that carry colour charges with interactions governed by Quantum Chromodynamics (QCD). How experiments (past, present and future) at Jefferson Lab probe colourless nuclei to map out these internal colour degrees of freedom is presented. When combined with theoretical calculations, these will paint a picture of how the confinement of quarks and gluons, and the structure of the QCD vacuum, determine the properties of all (light) strongly interacting states.

Competing Intramolecular vs. Intermolecular Hydrogen Bonds in Solution

PubMed Central

Nagy, Peter I.

2014-01-01

A hydrogen bond for a local-minimum-energy structure can be identified according to the definition of the International Union of Pure and Applied Chemistry (IUPAC recommendation 2011) or by finding a special bond critical point on the density map of the structure in the framework of the atoms-in-molecules theory. Nonetheless, a given structural conformation may be simply favored by electrostatic interactions. The present review surveys the in-solution competition of the conformations with intramolecular vs. intermolecular hydrogen bonds for different types of small organic molecules. In their most stable gas-phase structure, an intramolecular hydrogen bond is possible. In a protic solution, the intramolecular hydrogen bond may disrupt in favor of two solute-solvent intermolecular hydrogen bonds. The balance of the increased internal energy and the stabilizing effect of the solute-solvent interactions regulates the new conformer composition in the liquid phase. The review additionally considers the solvent effects on the stability of simple dimeric systems as revealed from molecular dynamics simulations or on the basis of the calculated potential of mean force curves. Finally, studies of the solvent effects on the type of the intermolecular hydrogen bond (neutral or ionic) in acid-base complexes have been surveyed. PMID:25353178

Direct Bio-printing with Heterogeneous Topology Design.

PubMed

Ahsan, Amm Nazmul; Xie, Ruinan; Khoda, Bashir

2017-01-01

Bio-additive manufacturing is a promising tool to fabricate porous scaffold structures for expediting the tissue regeneration processes. Unlike the most traditional bulk material objects, the microstructures of tissue and organs are mostly highly anisotropic, heterogeneous, and porous in nature. However, modelling the internal heterogeneity of tissues/organs structures in the traditional CAD environment is difficult and oftentimes inaccurate. Besides, the de facto STL conversion of bio-models introduces loss of information and piles up more errors in each subsequent step (build orientation, slicing, tool-path planning) of the bio-printing process plan. We are proposing a topology based scaffold design methodology to accurately represent the heterogeneous internal architecture of tissues/organs. An image analysis technique is used that digitizes the topology information contained in medical images of tissues/organs. A weighted topology reconstruction algorithm is implemented to represent the heterogeneity with parametric functions. The parametric functions are then used to map the spatial material distribution. The generated information is directly transferred to the 3D bio-printer and heterogeneous porous tissue scaffold structure is manufactured without STL file. The proposed methodology is implemented to verify the effectiveness of the approach and the designed example structure is bio-fabricated with a deposition based bio-additive manufacturing system.

In-cell RNA structure probing with SHAPE-MaP.

PubMed

Smola, Matthew J; Weeks, Kevin M

2018-06-01

This protocol is an extension to: Nat. Protoc. 10, 1643-1669 (2015); doi:10.1038/nprot.2015.103; published online 01 October 2015RNAs play key roles in many cellular processes. The underlying structure of RNA is an important determinant of how transcripts function, are processed, and interact with RNA-binding proteins and ligands. RNA structure analysis by selective 2'-hydroxyl acylation analyzed by primer extension (SHAPE) takes advantage of the reactivity of small electrophilic chemical probes that react with the 2'-hydroxyl group to assess RNA structure at nucleotide resolution. When coupled with mutational profiling (MaP), in which modified nucleotides are detected as internal miscodings during reverse transcription and then read out by massively parallel sequencing, SHAPE yields quantitative per-nucleotide measurements of RNA structure. Here, we provide an extension to our previous in vitro SHAPE-MaP protocol with detailed guidance for undertaking and analyzing SHAPE-MaP probing experiments in live cells. The MaP strategy works for both abundant-transcriptome experiments and for cellular RNAs of low to moderate abundance, which are not well examined by whole-transcriptome methods. In-cell SHAPE-MaP, performed in roughly 3 d, can be applied in cell types ranging from bacteria to cultured mammalian cells and is compatible with a variety of structure-probing reagents. We detail several strategies by which in-cell SHAPE-MaP can inform new biological hypotheses and emphasize downstream analyses that reveal sequence or structure motifs important for RNA interactions in cells.

Community Detection in Signed Networks: the Role of Negative ties in Different Scales

PubMed Central

Esmailian, Pouya; Jalili, Mahdi

2015-01-01

Extracting community structure of complex network systems has many applications from engineering to biology and social sciences. There exist many algorithms to discover community structure of networks. However, it has been significantly under-explored for networks with positive and negative links as compared to unsigned ones. Trying to fill this gap, we measured the quality of partitions by introducing a Map Equation for signed networks. It is based on the assumption that negative relations weaken positive flow from a node towards a community, and thus, external (internal) negative ties increase the probability of staying inside (escaping from) a community. We further extended the Constant Potts Model, providing a map spectrum for signed networks. Accordingly, a partition is selected through balancing between abridgment and expatiation of a signed network. Most importantly, multi-scale spectrum of signed networks revealed how informative are negative ties in different scales, and quantified the topological placement of negative ties between dense positive ones. Moreover, an inconsistency was found in the signed Modularity: as the number of negative ties increases, the density of positive ties is neglected more. These results shed lights on the community structure of signed networks. PMID:26395815

GTX Reference Vehicle Structural Verification Methods and Weight Summary

NASA Technical Reports Server (NTRS)

Hunter, J. E.; McCurdy, D. R.; Dunn, P. W.

2002-01-01

The design of a single-stage-to-orbit air breathing propulsion system requires the simultaneous development of a reference launch vehicle in order to achieve the optimal mission performance. Accordingly, for the GTX study a 300-lb payload reference vehicle was preliminary sized to a gross liftoff weight (GLOW) of 238,000 lb. A finite element model of the integrated vehicle/propulsion system was subjected to the trajectory environment and subsequently optimized for structural efficiency. This study involved the development of aerodynamic loads mapped to finite element models of the integrated system in order to assess vehicle margins of safety. Commercially available analysis codes were used in the process along with some internally developed spread-sheets and FORTRAN codes specific to the GTX geometry for mapping of thermal and pressure loads. A mass fraction of 0.20 for the integrated system dry weight has been the driver for a vehicle design consisting of state-of-the-art composite materials in order to meet the rigid weight requirements. This paper summarizes the methodology used for preliminary analyses and presents the current status of the weight optimization for the structural components of the integrated system.

GTX Reference Vehicle Structural Verification Methods and Weight Summary

NASA Technical Reports Server (NTRS)

Hunter, J. E.; McCurdy, D. R.; Dunn, P. W.

2002-01-01

The design of a single-stage-to-orbit air breathing propulsion system requires the simultaneous development of a reference launch vehicle in order to achieve the optimal mission performance. Accordingly, for the GTX study a 300-lb payload reference vehicle was preliminarily sized to a gross liftoff weight (GLOW) of 238,000 lb. A finite element model of the integrated vehicle/propulsion system was subjected to the trajectory environment and subsequently optimized for structural efficiency. This study involved the development of aerodynamic loads mapped to finite element models of the integrated system in order to assess vehicle margins of safety. Commercially available analysis codes were used in the process along with some internally developed spreadsheets and FORTRAN codes specific to the GTX geometry for mapping of thermal and pressure loads. A mass fraction of 0.20 for the integrated system dry weight has been the driver for a vehicle design consisting of state-of-the-art composite materials in order to meet the rigid weight requirements. This paper summarizes the methodology used for preliminary analyses and presents the current status of the weight optimization for the structural components of the integrated system.

75 FR 54695 - Noise Exposure Map Notice; Brownsville South Padre Island International Airport, Brownsville, TX

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-08

... Island International Airport under the provisions of 49 U.S.C. 47501 et seq. (Aviation Safety and Noise... of the Aviation Safety and Noise Abatement Act (hereinafter referred to as ``the Act''), an airport... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Noise Exposure Map Notice...

Data Immersion for CCNY Undergraduate Summer Interns at the IEDA Geoinformatics Facility

NASA Astrophysics Data System (ADS)

Uribe, R.; Van Wert, T.; Alabi, T.

2016-12-01

National Science Foundation (NSF) funded programs that provide grants and resources to enhance undergraduate learning and provide a pathway to future career opportunities in the geosciences by increasing retention and broadening participation. In an increasingly digital world, geoinformatics and the importance of large data storage and accessibility is a rapidly expanding field in the geosciences. The NSF-funded Interdisciplinary Earth Data Alliance (IEDA) - City College of New York (CCNY) summer internship program aims to provide diverse undergraduates from CCNY with data processing experience within the IEDA facility at Columbia University's Lamont-Doherty Earth Observatory (LDEO). CCNY interns worked alongside IEDA mentors and were immersed in the day-to-day operations of the IEDA facility. Skills necessary to work with geoscience data were developed throughout the internship and participation with the broader cohort of Lamont summer interns was promoted. Summer lectures delivered by researchers at LDEO provided interns with cutting-edge geoscience content from experts across a wide range of fields in the Earth sciences. CCNY undergraduate interns undertook two data compilation projects. First, interns compiled LiDAR land elevation data to enhance the land-ocean base map used across IEDA map-based resources. For that, the interns downloaded and classified one- and three-meter resolution LiDAR topographic data from the USGS The National Mapfor the lower 48 states. Second, computer-derived regional and global seismic tomography models from the Incorporated Research Institutions for Seismology (IRIS) were compiled and processed for integration with GeoMapApp, a free mapping application developed at LDEO (www.geomapapp.org). Interns established a data processing workflow to extract tomographic depth slices from dozens of tomographic grids. Executing LINUX commands and shell scripts, the native format binary netCDF files were resampled and reformatted and compared to the published figures to check for consistency. The extracted tomographic slices will be included in GeoMapApp's user friendly map-based interface. The IEDA-CCNY internship encouraged students to develop and build basic skills necessary for the rigors of graduate study and real world geoscience career exposure.

Data without Frontiers - the International Quaternary Map of Europe (IQUAME 2500)

NASA Astrophysics Data System (ADS)

Asch, Kristine

2017-04-01

The Federal German Geological Survey (Bundesanstalt für Geowissenschaften und Rohstoffe, BGR) is leading the review of the International Quaternary Map of Europe (IQUAME 2500) and its transformation into a geographical information system (GIS) under the umbrella of the CGMW and INQUA. It is a long-standing policy of BGR to lead international cooperation of European geological survey mapping projects. These particularly include projects under the umbrella of organisations including CGMW, UNESCO, INQUA, EGU and IUGS. The aim of IQUAME 2500 is to build a geological information system (GIS) of Europe's Quaternary geology where relevant information can be retrieved, combined and applied across international boundaries. Cross-border mapping poses specific challenges, in particular data harmonisation, for the presentation of regional geology. Overcoming these obstacles demands international cooperation with national geological survey organisations. Based on the previous BGR & UNESCO co-produced International Quaternary Map of Europe (at a 1 : 2,5 million scale; completed in 1995), revision was begun by BGR in 2011 to review the information available from an international group of experts from European geological survey organisations. This group is supported by an international academic Advisory Board. The work requires re-evaluation and digitization of the 14 paper sheets. For this purpose BGR developed a pragmatic procedure to classify, deliver and combine the reviewed Quaternary data in a harmonized and uniform manner. The project is applying the vocabularies and data model of the EC Directive INSPIRE Directive and is creating additional vocabularies and definitions for necessary features such as geomorphology (with the EMODnet project) and glaciogenic elements. An academic scientific advisory board is overseeing the process. Subjects of the map include: geological boundaries and classifications of Quaternary rocks, extension and boundaries of permafrost, last glacial maximum, genetic descriptions of the rocks, faults, key localities (geologically and palaeontologically significant sites, anthropological sites, impact craters, etc.) and more detailed off-shore geology (in cooperation with the EMODnet project). Ultimately, the IQUAME project will summarise the current status quo of European Quaternary geological research in a digitally available GIS synthesis and introduce practically applicable new vocabularies to describe the results and share those with the science community.

Use of Pressure Sensitive Paint for Diagnostics in Turbomachinery Flows With Shocks

NASA Technical Reports Server (NTRS)

Lepicovsky, Jan; Bencic, Timothy J.

2001-01-01

The technology of pressure sensitive paint (PSP) is well established in external aerodynamics. In internal flows in narrow channels and in turbomachinery cascades, however, there are still unresolved problems. In particular, the internal flows with complex shock structures inside highly curved channels present a challenge. It is not always easy and straightforward to distinguish between true signals and "ghost" images due to multiple internal reflections in narrow channels. To address some of the problems, investigations were first carried out in a narrow supersonic channel of Mach number 2.5. A single wedge or a combination of two wedges were used to generate a complex shock wave structure in the flow. The experience gained in a small supersonic channel was used for surface pressure measurements on the stator vane of a supersonic throughflow fan. The experimental results for several fan operating conditions are shown in a concise form, including performance map points, midspan static tap pressure distributions, and vane suction side pressure fields. Finally, the PSP technique was used in the NASA transonic flutter cascade to compliment flow visualization data and to acquire backwall pressure fields to assess the cascade flow periodicity. A summary of shortcomings of the pressure sensitive paint technology for internal flow application and lessons learned are presented in the conclusion of the paper.

Use of pressure-sensitive paint for diagnostics in turbomachinery flows with shocks

NASA Astrophysics Data System (ADS)

Lepicovsky, J.; Bencic, T. J.

2002-07-01

The technology of pressure-sensitive paint (PSP) is well established in external aerodynamics. In internal flows in narrow channels and in turbomachinery cascades, however, there are still unresolved problems. In particular, the internal flows with complex shock structures inside highly curved channels present a challenge. It is not always easy and straightforward to distinguish between true signals and 'ghost' images due to multiple internal reflections in narrow channels. To address some of the problems, investigations were first carried out in a narrow supersonic channel of Mach number 2.5. A single wedge or a combination of two wedges was used to generate a complex shock wave structure in the flow. The experience gained in a small supersonic channel was used for surface pressure measurements on the stator vane of a supersonic throughflow fan. The experimental results for several fan operating conditions are shown in a concise form, including performance map test points, midspan static tap pressure distributions, and vane suction side pressure fields. Finally, the PSP technique was used in the NASA transonic flutter cascade to compliment flow visualization data and to acquire backwall pressure fields to assess the cascade flow periodicity. Lessons learned from this investigation and shortcomings of the PSP technology for internal flow application are presented in the conclusion of the paper.

Noninvasive 3D Visualization of Defects and Crack Propagation in Layered Foam Structures by Phase Contrast Microimaging

NASA Technical Reports Server (NTRS)

Hu, Z. W.; DeCarlo, F.

2006-01-01

Applications of polymeric foams in our modern society continue to grow because of their light weight, high strength, excellent thermal and mechanical insulation, and the ease of engineering. Among others, closed-cell foam has been structurally used for thermally insulating the shuttle external tank. However, internal defects of the foams were difficult to observe non-invasively due to limited sensitivity to the low-density structures possessed by traditional imaging tools such as computed X-ray tomography By combining phase contrast X-ray imaging with pressure loading, we succeeded in precisely mapping intact cellular structure and defects inside the bulk of layered foam and visualizing its subsequent response to the pressure in three-dimensional space. The work demonstrated a powerfir1 approach for yielding insight into underlying problems in lightweight cellular materials otherwise unobtainable.

Cross-correlating 2D and 3D galaxy surveys

DOE PAGES

Passaglia, Samuel; Manzotti, Alessandro; Dodelson, Scott

2017-06-08

Galaxy surveys probe both structure formation and the expansion rate, making them promising avenues for understanding the dark universe. Photometric surveys accurately map the 2D distribution of galaxy positions and shapes in a given redshift range, while spectroscopic surveys provide sparser 3D maps of the galaxy distribution. We present a way to analyse overlapping 2D and 3D maps jointly and without loss of information. We represent 3D maps using spherical Fourier-Bessel (sFB) modes, which preserve radial coverage while accounting for the spherical sky geometry, and we decompose 2D maps in a spherical harmonic basis. In these bases, a simple expression exists for the cross-correlation of the two fields. One very powerful application is the ability to simultaneously constrain the redshift distribution of the photometric sample, the sample biases, and cosmological parameters. We use our framework to show that combined analysis of DESI and LSST can improve cosmological constraints by factors ofmore » $${\\sim}1.2$$ to $${\\sim}1.8$$ on the region where they overlap relative to identically sized disjoint regions. We also show that in the overlap of DES and SDSS-III in Stripe 82, cross-correlating improves photo-$z$ parameter constraints by factors of $${\\sim}2$$ to $${\\sim}12$$ over internal photo-$z$ reconstructions.« less

Cross-correlating 2D and 3D galaxy surveys

DOE Office of Scientific and Technical Information (OSTI.GOV)

Passaglia, Samuel; Manzotti, Alessandro; Dodelson, Scott

Galaxy surveys probe both structure formation and the expansion rate, making them promising avenues for understanding the dark universe. Photometric surveys accurately map the 2D distribution of galaxy positions and shapes in a given redshift range, while spectroscopic surveys provide sparser 3D maps of the galaxy distribution. We present a way to analyse overlapping 2D and 3D maps jointly and without loss of information. We represent 3D maps using spherical Fourier-Bessel (sFB) modes, which preserve radial coverage while accounting for the spherical sky geometry, and we decompose 2D maps in a spherical harmonic basis. In these bases, a simple expression exists for the cross-correlation of the two fields. One very powerful application is the ability to simultaneously constrain the redshift distribution of the photometric sample, the sample biases, and cosmological parameters. We use our framework to show that combined analysis of DESI and LSST can improve cosmological constraints by factors ofmore » $${\\sim}1.2$$ to $${\\sim}1.8$$ on the region where they overlap relative to identically sized disjoint regions. We also show that in the overlap of DES and SDSS-III in Stripe 82, cross-correlating improves photo-$z$ parameter constraints by factors of $${\\sim}2$$ to $${\\sim}12$$ over internal photo-$z$ reconstructions.« less

Study of Structure and Small-Scale Fragmentation in TMC-1

NASA Technical Reports Server (NTRS)

Langer, W. D.; Velusamy, T.; Kuiper, T. B.; Levin, S.; Olsen, E.; Migenes, V.

1995-01-01

Large-scale C(sup 18)O maps show that the Taurus molecular cloud 1 (TMC-1) has numerous cores located along a ridge which extends about 12 minutes by at least 35 minutes. The cores traced by C(sup 18)O are about a few arcminutes (0.1-0.2 pc) in extent, typically contain about 0.5-3 solar mass, and are probably gravitationally bound. We present a detailed study of the small-scale fragmentary structure of one of these cores, called core D, within TMC-1 using very high spectral and spatial resolution maps of CCS and CS. The CCS lines are excellent tracers for investigating the density, temperature, and velocity structure in dense cores. The high spectral resolution, 0.008 km /s, data consist mainly of single-dish, Nyquist-sampled maps of CCS at 22 GHz with 45 sec spatial resolution taken with NASA's 70 m DSN antenna at Goldstone. The high spatial resolution spectral line maps were made with the Very Large Array (9 sec resolution) at 22 GHz and with the OVRO millimeter array in CCS and CS at 93 GHz and 98 GHz, respectively, with 6 sec resolution. These maps are supplemented with single-dish observations of CCS and CC(sup 34)S spectra at 33 GHz using a NASA 34 m DSN antenna, CCS 93 GHz, C(sup 34)S (2-1), and C(sup 18)O (1-0) single-dish observations made with the AT&T Bell Laboratories 7 m antenna. Our high spectral and spatial CCS and CS maps show that core D is highly fragmented. The single-dish CCS observations map out several clumps which range in size from approx. 45 sec to 90 sec (0.03-0.06 pc). These clumps have very narrow intrinsic line widths, 0.11-0.25 km/s, slightly larger than the thermal line width for CCS at 10 K, and masses about 0.03-0.2 solar mass. Interferometer observations of some of these clumps show that they have considerable additional internal structure, consisting of several condensations ranging in size from approx. 10 sec- 30 sec (0.007-0.021 pc), also with narrow line widths. The mass of these smallest fragments is of order 0.01 solar mass. These small-scale structures traced by CCS appear to be gravitationally unbound by a large factor. Most of these objects have masses that fall below those of the putative proto-brown dwarfs (approx. less than 0.1 solar mass). The presence of many small gravitationally unbound clumps suggests that fragmentation mechanisms other than a purely Jeans gravitational instability may be important for the dynamics of these cold dense cores.

An integrative theory of prefrontal cortex function.

PubMed

Miller, E K; Cohen, J D

2001-01-01

The prefrontal cortex has long been suspected to play an important role in cognitive control, in the ability to orchestrate thought and action in accordance with internal goals. Its neural basis, however, has remained a mystery. Here, we propose that cognitive control stems from the active maintenance of patterns of activity in the prefrontal cortex that represent goals and the means to achieve them. They provide bias signals to other brain structures whose net effect is to guide the flow of activity along neural pathways that establish the proper mappings between inputs, internal states, and outputs needed to perform a given task. We review neurophysiological, neurobiological, neuroimaging, and computational studies that support this theory and discuss its implications as well as further issues to be addressed

Constructing a strategy map for banking institutions with key performance indicators of the balanced scorecard.

PubMed

Wu, Hung-Yi

2012-08-01

This study presents a structural evaluation methodology to link key performance indicators (KPIs) into a strategy map of the balanced scorecard (BSC) for banking institutions. Corresponding with the four BSC perspectives (finance, customer, internal business process, and learning and growth), the most important evaluation indicators of banking performance are synthesized from the relevant literature and screened by a committee of experts. The Decision Making Trial and Evaluation Laboratory (DEMATEL) method, a multiple criteria analysis tool, is then employed to determine the causal relationships between the KPIs, to identify the critical central and influential factors, and to establish a visualized strategy map with logical links to improve banking performance. An empirical application is provided as an example. According to the expert evaluations, the three most essential KPIs for banking performance are customer satisfaction, sales performance, and customer retention rate. The DEMATEL results demonstrate a clear road map to assist management in prioritizing the performance indicators and in focusing attention on the strategy-related activities of the crucial indicators. According to the constructed strategy map, management could better invest limited resources in the areas that need improvement most. Although these strategy maps of the BSC are not universal, the research results show that the presented approach is an objective and feasible way to construct strategy maps more justifiably. The proposed framework can be applicable to institutions in other industries as well. Copyright © 2011 Elsevier Ltd. All rights reserved.

The dynamical environment of asteroid 21 Lutetia according to different internal models

NASA Astrophysics Data System (ADS)

Aljbaae, S.; Chanut, T. G. G.; Carruba, V.; Souchay, J.; Prado, A. F. B. A.; Amarante, A.

2017-01-01

One of the most accurate models currently used to represent the gravity field of irregular bodies is the polyhedral approach. In this model, the mass of the body is assumed to be homogeneous, which may not be true for a real object. The main goal of the this paper is to study the dynamical effects induced by three different internal structures (uniform, three- and four-layered) of asteroid (21) Lutetia, an object that recent results from space probe suggest being at least partially differentiated. The Mascon gravity approach used in the this work consists of dividing each tetrahedron into eight parts to calculate the gravitational field around the asteroid. The zero-velocity curves show that the greatest displacement of the equilibrium points occurs in the position of the E4 point for the four-layered structure and the smallest one occurs in the position of the E3 point for the three-layered structure. Moreover, stability against impact shows that the planar limit gets slightly closer to the body with the four-layered structure. We then investigated the stability of orbital motion in the equatorial plane of (21) Lutetia and propose numerical stability criteria to map the region of stable motions. Layered structures could stabilize orbits that were unstable in the homogeneous model.

PDBe: Protein Data Bank in Europe

PubMed Central

Velankar, Sameer; Alhroub, Younes; Alili, Anaëlle; Best, Christoph; Boutselakis, Harry C.; Caboche, Ségolène; Conroy, Matthew J.; Dana, Jose M.; van Ginkel, Glen; Golovin, Adel; Gore, Swanand P.; Gutmanas, Aleksandras; Haslam, Pauline; Hirshberg, Miriam; John, Melford; Lagerstedt, Ingvar; Mir, Saqib; Newman, Laurence E.; Oldfield, Tom J.; Penkett, Chris J.; Pineda-Castillo, Jorge; Rinaldi, Luana; Sahni, Gaurav; Sawka, Grégoire; Sen, Sanchayita; Slowley, Robert; Sousa da Silva, Alan Wilter; Suarez-Uruena, Antonio; Swaminathan, G. Jawahar; Symmons, Martyn F.; Vranken, Wim F.; Wainwright, Michael; Kleywegt, Gerard J.

2011-01-01

The Protein Data Bank in Europe (PDBe; pdbe.org) is actively involved in managing the international archive of biomacromolecular structure data as one of the partners in the Worldwide Protein Data Bank (wwPDB; wwpdb.org). PDBe also develops new tools to make structural data more widely and more easily available to the biomedical community. PDBe has developed a browser to access and analyze the structural archive using classification systems that are familiar to chemists and biologists. The PDBe web pages that describe individual PDB entries have been enhanced through the introduction of plain-English summary pages and iconic representations of the contents of an entry (PDBprints). In addition, the information available for structures determined by means of NMR spectroscopy has been expanded. Finally, the entire web site has been redesigned to make it substantially easier to use for expert and novice users alike. PDBe works closely with other teams at the European Bioinformatics Institute (EBI) and in the international scientific community to develop new resources with value-added information. The SIFTS initiative is an example of such a collaboration—it provides extensive mapping data between proteins whose structures are available from the PDB and a host of other biomedical databases. SIFTS is widely used by major bioinformatics resources. PMID:21045060

Analysis of mechanical behavior of implant-supported prostheses in the anterior maxilla: analysis by speckle pattern interferometry

NASA Astrophysics Data System (ADS)

Corrêa, Cássia B.; Ramos, Nuno V.; Monteiro, Jaime; Vaz, Luis G.; Vaz, Mario A. P.

2012-10-01

The use of implants to rehabilitation of total edentulous, partial edentulous or single tooth is increasing, it is due to the high rate of success that this type of treatment present. The objective of this study was to analyze the mechanical behavior of different positions of two dental implants in a rehabilitation of 4 teeth in the region of maxilla anterior. The groups studied were divided according the positioning of the implants. The Group 1: Internal Hexagonal implant in position of lateral incisors and pontic in region of central incisors; Group 2: Internal Hexagonal implant in position of central incisors and cantilever of the lateral incisors and Group3 - : Internal Hexagonal implants alternate with suspended elements. The Electronic Speckle Pattern Interferometry (ESPI) technique was selected for the mechanical evaluation of the 3 groups performance. The results are shown in interferometric phase maps representing the displacement field of the prosthetic structure.

High-Resolution Forest Carbon Monitoring and Modeling: Continued Prototype Development and Deployment Across The Tri-state Area (MD, PA, DE), USA

NASA Astrophysics Data System (ADS)

Hurtt, G. C.; Birdsey, R.; Campbell, E.; Dolan, K. A.; Dubayah, R.; Escobar, V. M.; Finley, A. O.; Flanagan, S.; Huang, W.; Johnson, K.; Lister, A.; ONeil-Dunne, J.; Sepulveda Carlo, E.; Zhao, M.

2017-12-01

Local, national and international programs have increasing need for precise and accurate estimates of forest carbon and structure to support greenhouse gas reduction plans, climate initiatives, and other international climate treaty frameworks. In 2010 Congress directed NASA to initiate research towards the development of Carbon Monitoring Systems (CMS). In response, our team has worked to develop a robust, replicable framework to produce maps of high-resolution carbon stocks and future carbon sequestration potential. High-resolution (30m) maps of carbon stocks and uncertainty were produced by linking national 1m-resolution imagery and existing wall-to-wall airborne lidar to spatially explicit in-situ field observations such as the USFS Forest Inventory and Analysis (FIA) network. These same data, characterizing forest extent and vertical structure, were used to drive a prognostic ecosystem model to predict carbon fluxes and carbon sequestration potential at unprecedented spatial resolution and scale (90m), more than 100,000 times the spatial resolution of standard global models. Through project development, the domain of this research has expanded from two counties in MD (2,181 km2), to the entire state (32,133 km2), to the tri-state region of MD, PA, and DE (157,868 km2), covering forests in four major USDA ecological providences (Eastern Broadleaf, Northeastern Mixed, Outer Coastal Plain, and Central Appalachian). Across the region, we estimate 694 Tg C (14 DE, 113 MD, 567 PA) in above ground biomass, and estimate a carbon sequestration potential more than twice that amount. Empirical biomass products enhance existing approaches though high resolution accounting for trees outside traditional forest maps. Modeling products move beyond traditional MRV, and map future afforestation and reforestation potential for carbon at local actionable spatial scales. These products are relevant to multiple stakeholder needs in the region as discussed through the Tri-sate Working Group, and are actively being used to inform the state of MD's Greenhouse Gas Reduction Act. The approach is scalable, and provides a protoype framework for application in other domains and for future spaceborne lidar missions.

Modeling and Mapping Personal Learning Environment of Thai International Higher Education Students

ERIC Educational Resources Information Center

Sharafuddin, Mohamed Ali; Sawad, Buncha Panacharoen; Wongwai, Sarun

2018-01-01

This research article is part of a periodic study conducted to understand, model, map and to develop an integrated approach for effective and interactive self-learning phases of Thai International Hospitality and Tourism higher education students. Questionnaire containing both qualitative and quantitative questions was distributed at the beginning…

Automatic public access to documents and maps stored on and internal secure system.

NASA Astrophysics Data System (ADS)

Trench, James; Carter, Mary

2013-04-01

The Geological Survey of Ireland operates a Document Management System for providing documents and maps stored internally in high resolution and in a high level secure environment, to an external service where the documents are automatically presented in a lower resolution to members of the public. Security is devised through roles and Individual Users where role level and folder level can be set. The application is an electronic document/data management (EDM) system which has a Geographical Information System (GIS) component integrated to allow users to query an interactive map of Ireland for data that relates to a particular area of interest. The data stored in the database consists of Bedrock Field Sheets, Bedrock Notebooks, Bedrock Maps, Geophysical Surveys, Geotechnical Maps & Reports, Groundwater, GSI Publications, Marine, Mine Records, Mineral Localities, Open File, Quaternary and Unpublished Reports. The Konfig application Tool is both an internal and public facing application. It acts as a tool for high resolution data entry which are stored in a high resolution vault. The public facing application is a mirror of the internal application and differs only in that the application furnishes high resolution data into low resolution format which is stored in a low resolution vault thus, making the data web friendly to the end user for download.

Initial constructs for patient-centered outcome measures to evaluate brain-computer interfaces

PubMed Central

Andresen, Elena M.; Fried-Oken, Melanie; Peters, Betts; Patrick, Donald L.

2016-01-01

Purpose The authors describe preliminary work toward the creation of patient-centered outcome (PCO) measures to evaluate brain-computer interface (BCI) as an assistive technology for individuals with severe speech and physical impairments (SSPI). Method In Phase 1, 591 items from 15 existing measures were mapped to the International Classification of Functioning, Disability and Health (ICF). In Phase 2, qualitative interviews were conducted with eight people with SSPI and seven caregivers. Resulting text data were coded in an iterative analysis. Results Most items (79%) mapped to the ICF environmental domain; over half (53%) mapped to more than one domain. The ICF framework was well suited for mapping items related to body functions and structures, but less so for items in other areas, including personal factors. Two constructs emerged from qualitative data: Quality of Life (QOL) and Assistive Technology. Component domains and themes were identified for each. Conclusions Preliminary constructs, domains, and themes were generated for future PCO measures relevant to BCI. Existing instruments are sufficient for initial items but do not adequately match the values of people with SSPI and their caregivers. Field methods for interviewing people with SSPI were successful, and support the inclusion of these individuals in PCO research. PMID:25806719

Decoupling local mechanics from large-scale structure in modular metamaterials.

PubMed

Yang, Nan; Silverberg, Jesse L

2017-04-04

A defining feature of mechanical metamaterials is that their properties are determined by the organization of internal structure instead of the raw fabrication materials. This shift of attention to engineering internal degrees of freedom has coaxed relatively simple materials into exhibiting a wide range of remarkable mechanical properties. For practical applications to be realized, however, this nascent understanding of metamaterial design must be translated into a capacity for engineering large-scale structures with prescribed mechanical functionality. Thus, the challenge is to systematically map desired functionality of large-scale structures backward into a design scheme while using finite parameter domains. Such "inverse design" is often complicated by the deep coupling between large-scale structure and local mechanical function, which limits the available design space. Here, we introduce a design strategy for constructing 1D, 2D, and 3D mechanical metamaterials inspired by modular origami and kirigami. Our approach is to assemble a number of modules into a voxelized large-scale structure, where the module's design has a greater number of mechanical design parameters than the number of constraints imposed by bulk assembly. This inequality allows each voxel in the bulk structure to be uniquely assigned mechanical properties independent from its ability to connect and deform with its neighbors. In studying specific examples of large-scale metamaterial structures we show that a decoupling of global structure from local mechanical function allows for a variety of mechanically and topologically complex designs.

Decoupling local mechanics from large-scale structure in modular metamaterials

NASA Astrophysics Data System (ADS)

Yang, Nan; Silverberg, Jesse L.

2017-04-01

A defining feature of mechanical metamaterials is that their properties are determined by the organization of internal structure instead of the raw fabrication materials. This shift of attention to engineering internal degrees of freedom has coaxed relatively simple materials into exhibiting a wide range of remarkable mechanical properties. For practical applications to be realized, however, this nascent understanding of metamaterial design must be translated into a capacity for engineering large-scale structures with prescribed mechanical functionality. Thus, the challenge is to systematically map desired functionality of large-scale structures backward into a design scheme while using finite parameter domains. Such “inverse design” is often complicated by the deep coupling between large-scale structure and local mechanical function, which limits the available design space. Here, we introduce a design strategy for constructing 1D, 2D, and 3D mechanical metamaterials inspired by modular origami and kirigami. Our approach is to assemble a number of modules into a voxelized large-scale structure, where the module’s design has a greater number of mechanical design parameters than the number of constraints imposed by bulk assembly. This inequality allows each voxel in the bulk structure to be uniquely assigned mechanical properties independent from its ability to connect and deform with its neighbors. In studying specific examples of large-scale metamaterial structures we show that a decoupling of global structure from local mechanical function allows for a variety of mechanically and topologically complex designs.

A Comparative Analysis of the Magnetic Field Signals over Impact Structures on the Earth, Mars and the Moon

NASA Technical Reports Server (NTRS)

Isac, Anca; Mandea, Mioara; Purucker, Michael; Langlais, Benoit

2015-01-01

An improved description of magnetic fields of terrestrial bodies has been obtained from recent space missions, leading to a better characterization of the internal fields including those of crustal origin. One of the striking differences in their crustal magnetic field is the signature of large impact craters. A comparative analysis of the magnetic characteristics of these structures can shed light on the history of their respective planetary-scale magnetic dynamos. This has motivated us to identify impact craters and basins, first by their quasi-circular features from the most recent and detailed topographic maps and then from available global magnetic field maps. We have examined the magnetic field observed above 27 complex craters on the Earth, 34 impact basins on Mars and 37 impact basins on the Moon. For the first time, systematic trends in the amplitude and frequency of the magnetic patterns, inside and outside of these structures are observed for all three bodies. The demagnetization effects due to the impact shock wave and excavation processes have been evaluated applying the Equivalent Source Dipole forward modeling approach. The main characteristics of the selected impact craters are shown. The trends in their magnetic signatures are indicated, which are related to the presence or absence of a planetary-scale dynamo at the time of their formation and to impact processes. The low magnetic field intensity at center can be accepted as the prime characteristic of a hypervelocity impact and strongly associated with the mechanics of impact crater formation. In the presence of an active internal field, the process of demagnetization due to the shock impact is associated with post-impact remagnetization processes, generating a more complex magnetic signature.

Microgravity

NASA Image and Video Library

1999-04-21

University of Alabama engineer Stacey Giles briefs NASA astronaut Dr. Bornie Dunbar about the design and capabilities of the X-ray Crystallography Facility under development at the Center for Macromolecular Crystallography of the University of Alabama at Birmingham, AL, April 21, 1999. The X-ray Crystallography Facility is designed to speed the collection of protein structure information from crystals grown aboard the International Space Station. By measuring and mapping the protein crystal structure in space, researchers will avoid exposing the delicate crystals to the rigors of space travel and make important research data available to scientists much faster. The X-ray Crystallography facility is being designed and developed by the Center for Macromolecular Crystallography of the University of Alabama at Birmingham, a NASA Commercial Space Center.

Microgravity

NASA Image and Video Library

1999-04-21

University of Alabama engineer Lance Weiss briefs NASA astronaut Dr. Bornie Dunbar about the design and capabilities of the X-ray Crystallography Facility under development at the Center for Macromolecular Crystallography of the University of Alabama at Birmingham, AL, April 21, 1999. The X-ray Crystallography Facility is designed to speed the collection of protein structure information from crystals grown aboard the International Space Station. By measuring and mapping the protein crystal structure in space, researchers will avoid exposing the delicate crystals to the rigors of space travel and make important research data available to scientists much faster. The X-ray Crystallography facility is being designed and developed by the Center for Macromolecular Crystallography of the University of Alabama at Birmingham, a NASA Commercial Space Center.

A novel visual pipework inspection system

NASA Astrophysics Data System (ADS)

Summan, Rahul; Jackson, William; Dobie, Gordon; MacLeod, Charles; Mineo, Carmelo; West, Graeme; Offin, Douglas; Bolton, Gary; Marshall, Stephen; Lille, Alexandre

2018-04-01

The interior visual inspection of pipelines in the nuclear industry is a safety critical activity conducted during outages to ensure the continued safe and reliable operation of plant. Typically, the video output by a manually deployed probe is viewed by an operator looking to identify and localize surface defects such as corrosion, erosion and pitting. However, it is very challenging to estimate the nature and extent of defects by viewing a large structure through a relatively small field of view. This work describes a new visual inspection system employing photogrammetry using a fisheye camera and a structured light system to map the internal geometry of pipelines by generating a photorealistic, geometrically accurate surface model. The error of the system output was evaluated through comparison to a ground truth laser scan (ATOS GOM Triple Scan) of a nuclear grade split pipe sample (stainless steel 304L, 80mm internal diameter) containing defects representative of the application - the error was found to be submillimeter across the sample.

Outreach Programmes for Education and Training: Contributions from the International Cartographic Association

NASA Astrophysics Data System (ADS)

Cartwright, W. E.; Fairbairn, D.

2012-07-01

Organisations like the International Cartographic Association champion programmes that develop and deliver education and training to cartographers and geospatial scientists, globally. This can be in the form of traditional university and training college programmes, short courses for professional and technical members of mapping agencies and as outreach initiatives to transfer knowledge about the discipline and its contemporary practices. Through its international community, the ICA undertakes the transfer of knowledge about cartography and GI Science by publishing books and special editions of journals and running workshops. Colleagues from the ICA community conduct these workshops on a volunteer basis, generally with the support of the national member organisation of ICA or the national mapping body. For example, the ICA promotes the generation of extensive publications, generally through its Commissions and Working Groups. The publications include books, journals and the ICA Newsletter. Outreach activities are especially pertinent to up skill colleagues from developing countries. Specialist programmes can be offered for professional and 'everyday' map users (from adults to children). The ICA can assist with its current programmes, designed to embrace professional and non-professional cartographers alike. This paper will address how education and outreach programmes can be supported by international associations, by offering programmes independently, or in partnership with sister associations and national and regional organisations and societies. As well, the paper will address the need to deliver education and outreach programmes not to just the professional international community, but also to map users and citizen map publishers.

MC EMiNEM maps the interaction landscape of the Mediator.

PubMed

Niederberger, Theresa; Etzold, Stefanie; Lidschreiber, Michael; Maier, Kerstin C; Martin, Dietmar E; Fröhlich, Holger; Cramer, Patrick; Tresch, Achim

2012-01-01

The Mediator is a highly conserved, large multiprotein complex that is involved essentially in the regulation of eukaryotic mRNA transcription. It acts as a general transcription factor by integrating regulatory signals from gene-specific activators or repressors to the RNA Polymerase II. The internal network of interactions between Mediator subunits that conveys these signals is largely unknown. Here, we introduce MC EMiNEM, a novel method for the retrieval of functional dependencies between proteins that have pleiotropic effects on mRNA transcription. MC EMiNEM is based on Nested Effects Models (NEMs), a class of probabilistic graphical models that extends the idea of hierarchical clustering. It combines mode-hopping Monte Carlo (MC) sampling with an Expectation-Maximization (EM) algorithm for NEMs to increase sensitivity compared to existing methods. A meta-analysis of four Mediator perturbation studies in Saccharomyces cerevisiae, three of which are unpublished, provides new insight into the Mediator signaling network. In addition to the known modular organization of the Mediator subunits, MC EMiNEM reveals a hierarchical ordering of its internal information flow, which is putatively transmitted through structural changes within the complex. We identify the N-terminus of Med7 as a peripheral entity, entailing only local structural changes upon perturbation, while the C-terminus of Med7 and Med19 appear to play a central role. MC EMiNEM associates Mediator subunits to most directly affected genes, which, in conjunction with gene set enrichment analysis, allows us to construct an interaction map of Mediator subunits and transcription factors.

"MASSIVE" brain dataset: Multiple acquisitions for standardization of structural imaging validation and evaluation.

PubMed

Froeling, Martijn; Tax, Chantal M W; Vos, Sjoerd B; Luijten, Peter R; Leemans, Alexander

2017-05-01

In this work, we present the MASSIVE (Multiple Acquisitions for Standardization of Structural Imaging Validation and Evaluation) brain dataset of a single healthy subject, which is intended to facilitate diffusion MRI (dMRI) modeling and methodology development. MRI data of one healthy subject (female, 25 years) were acquired on a clinical 3 Tesla system (Philips Achieva) with an eight-channel head coil. In total, the subject was scanned on 18 different occasions with a total acquisition time of 22.5 h. The dMRI data were acquired with an isotropic resolution of 2.5 mm 3 and distributed over five shells with b-values up to 4000 s/mm 2 and two Cartesian grids with b-values up to 9000 s/mm 2 . The final dataset consists of 8000 dMRI volumes, corresponding B 0 field maps and noise maps for subsets of the dMRI scans, and ten three-dimensional FLAIR, T 1 -, and T 2 -weighted scans. The average signal-to-noise-ratio of the non-diffusion-weighted images was roughly 35. This unique set of in vivo MRI data will provide a robust framework to evaluate novel diffusion processing techniques and to reliably compare different approaches for diffusion modeling. The MASSIVE dataset is made publically available (both unprocessed and processed) on www.massive-data.org. Magn Reson Med 77:1797-1809, 2017. © 2016 International Society for Magnetic Resonance in Medicine. © 2016 International Society for Magnetic Resonance in Medicine.

Mediastinal lymph node detection and station mapping on chest CT using spatial priors and random forest

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, Jiamin; Hoffman, Joanne; Zhao, Jocelyn

2016-07-15

Purpose: To develop an automated system for mediastinal lymph node detection and station mapping for chest CT. Methods: The contextual organs, trachea, lungs, and spine are first automatically identified to locate the region of interest (ROI) (mediastinum). The authors employ shape features derived from Hessian analysis, local object scale, and circular transformation that are computed per voxel in the ROI. Eight more anatomical structures are simultaneously segmented by multiatlas label fusion. Spatial priors are defined as the relative multidimensional distance vectors corresponding to each structure. Intensity, shape, and spatial prior features are integrated and parsed by a random forest classifiermore » for lymph node detection. The detected candidates are then segmented by the following curve evolution process. Texture features are computed on the segmented lymph nodes and a support vector machine committee is used for final classification. For lymph node station labeling, based on the segmentation results of the above anatomical structures, the textual definitions of mediastinal lymph node map according to the International Association for the Study of Lung Cancer are converted into patient-specific color-coded CT image, where the lymph node station can be automatically assigned for each detected node. Results: The chest CT volumes from 70 patients with 316 enlarged mediastinal lymph nodes are used for validation. For lymph node detection, their system achieves 88% sensitivity at eight false positives per patient. For lymph node station labeling, 84.5% of lymph nodes are correctly assigned to their stations. Conclusions: Multiple-channel shape, intensity, and spatial prior features aggregated by a random forest classifier improve mediastinal lymph node detection on chest CT. Using the location information of segmented anatomic structures from the multiatlas formulation enables accurate identification of lymph node stations.« less

Geologic Map of the Mount Trumbull 30' X 60' Quadrangle, Mohave and Coconino Counties, Northwestern Arizona

USGS Publications Warehouse

Billingsley, George H.; Wellmeyer, Jessica L.

2003-01-01

The geologic map of the Mount Trumbull 30' x 60' quadrangle is a cooperative product of the U.S. Geological Survey, the National Park Service, and the Bureau of Land Management that provides geologic map coverage and regional geologic information for visitor services and resource management of Grand Canyon National Park, Lake Mead Recreational Area, and Grand Canyon Parashant National Monument, Arizona. This map is a compilation of previous and new geologic mapping that encompasses the Mount Trumbull 30' x 60' quadrangle of Arizona. This digital database, a compilation of previous and new geologic mapping, contains geologic data used to produce the 100,000-scale Geologic Map of the Mount Trumbull 30' x 60' Quadrangle, Mohave and Coconino Counties, Northwestern Arizona. The geologic features that were mapped as part of this project include: geologic contacts and faults, bedrock and surficial geologic units, structural data, fold axes, karst features, mines, and volcanic features. This map was produced using 1:24,000-scale 1976 infrared aerial photographs followed by extensive field checking. Volcanic rocks were mapped as separate units when identified on aerial photographs as mappable and distinctly separate units associated with one or more pyroclastic cones and flows. Many of the Quaternary alluvial deposits that have similar lithology but different geomorphic characteristics were mapped almost entirely by photogeologic methods. Stratigraphic position and amount of erosional degradation were used to determine relative ages of alluvial deposits having similar lithologies. Each map unit and structure was investigated in detail in the field to ensure accuracy of description. Punch-registered mylar sheets were scanned at the Flagstaff Field Center using an Optronics 5040 raster scanner at a resolution of 50 microns (508 dpi). The scans were output in .rle format, converted to .rlc, and then converted to ARC/INFO grids. A tic file was created in geographic coordinates and projected into the base map projection (Polyconic) using a central meridian of -113.500. The tic file was used to transform the grid into Universal Transverse Mercator projection. The linework was vectorized using gridline. Scanned lines were edited interactively in ArcEdit. Polygons were attributed in ArcEdit and all artifacts and scanning errors visible at 1:100,000 were removed. Point data were digitized onscreen. Due to the discovery of digital and geologic errors on the original files, the ARC/INFO coverages were converted to a personal geodatabase and corrected in ArcMap. The feature classes which define the geologic units, lines and polygons, are topologically related and maintained in the geodatabase by a set of validation rules. The internal database structure and feature attributes were then modified to match other geologic map databases being created for the Grand Canyon region. Faults were edited with the downthrown block, if known, on the 'right side' of the line. The 'right' and 'left' sides of a line are determined from 'starting' at the line's 'from node' and moving to the line's end or 'to node'.

World Digital Magnetic Anomaly Map version 2 (WDMAM v.2) - released for research and education

NASA Astrophysics Data System (ADS)

CHOI-Dyment, Y.; Lesur, V.; Dyment, J.; Hamoudi, M.; Thebault, E.; Catalan, M.

2015-12-01

The World Digital Magnetic Anomaly Map is an international initiative carried out under the auspices of the International Association of Geomagnetism and Aeronomy (IAGA) and the Commission for the Geological Map of the World (CGMW). A first version of the map has been published and distributed eight years ago (WDMAM v1; Korhonen et al., 2007). We have produced a candidate which has been accepted as the second version of this map (WDMAM v2) at the International Union of Geophysics and Geodesy in Prag, in June 2015. On land, we adopted an alternative approach avoiding any unnecessary processing on existing aeromagnetic compilations. When available, we used the original aeromagnetic data. As a result the final compilation remains an acceptable representation of the national and international data grids. Over oceanic areas the marine data have been extended. In areas of insufficient data coverage, a model has been computed based on a modified digital grid of the oceanic lithosphere age, considering plate motions in the determination of magnetization vector directions. This model has been further adjusted to the available data, resulting in a better representation of the anomalies. The final grid will be periodically upgraded. Version 2.0 has been released and is available at wdmam.org to support both research and education projects. Colleagues willing to contribute data for future releases (and become a co-author of the map) should contact any of the authors or Jerome Dyment (chair of the WDMAM Task Force) at jdy@ipgp.fr .

Oil Exploration Mapping

NASA Technical Reports Server (NTRS)

1994-01-01

After concluding an oil exploration agreement with the Republic of Yemen, Chevron International needed detailed geologic and topographic maps of the area. Chevron's remote sensing team used imagery from Landsat and SPOT, combining images into composite views. The project was successfully concluded and resulted in greatly improved base maps and unique topographic maps.

Mapping of the Lassa virus LAMP1 binding site reveals unique determinants not shared by other old world arenaviruses.

PubMed

Israeli, Hadar; Cohen-Dvashi, Hadas; Shulman, Anastasiya; Shimon, Amir; Diskin, Ron

2017-04-01

Cell entry of many enveloped viruses occurs by engagement with cellular receptors, followed by internalization into endocytic compartments and pH-induced membrane fusion. A previously unnoticed step of receptor switching was found to be critical during cell entry of two devastating human pathogens: Ebola and Lassa viruses. Our recent studies revealed the functional role of receptor switching to LAMP1 for triggering membrane fusion by Lassa virus and showed the involvement of conserved histidines in this switching, suggesting that other viruses from this family may also switch to LAMP1. However, when we investigated viruses that are genetically close to Lassa virus, we discovered that they cannot bind LAMP1. A crystal structure of the receptor-binding module from Morogoro virus revealed structural differences that allowed mapping of the LAMP1 binding site to a unique set of Lassa residues not shared by other viruses in its family, illustrating a key difference in the cell-entry mechanism of Lassa virus that may contribute to its pathogenicity.

KSC-2011-6782

NASA Image and Video Library

2011-09-08

CAPE CANAVERAL, Fla. -- At Space Launch Complex 17B on Cape Canaveral Air Force Station, the United Launch Alliance Delta II rocket that will launch NASA's Gravity Recovery and Interior Laboratory mission towers over the U.S. flag painted on the pad's structure. The mobile service tower has been rolled away from the vehicle for launch. The "rollback" began at about 11:20 p.m. EDT Sept. 7. GRAIL will fly twin spacecraft in tandem around the moon to precisely measure and map variations in the moon's gravitational field. The mission will provide the most accurate global gravity field to date for any planet, including Earth. This detailed information will reveal differences in the density of the moon's crust and mantle and will help answer fundamental questions about the moon's internal structure, thermal evolution, and history of collisions with asteroids. The aim is to map the moon's gravity field so completely that future lunar vehicles can safely navigate anywhere on the moon’s surface. Launch is scheduled for 8:37:06 a.m. EDT Sept. 8. For more information, visit http://www.nasa.gov/grail. Photo credit: NASA/Kim Shiflett

Template‐based field map prediction for rapid whole brain B0 shimming

PubMed Central

Shi, Yuhang; Vannesjo, S. Johanna; Miller, Karla L.

2017-01-01

Purpose In typical MRI protocols, time is spent acquiring a field map to calculate the shim settings for best image quality. We propose a fast template‐based field map prediction method that yields near‐optimal shims without measuring the field. Methods The template‐based prediction method uses prior knowledge of the B0 distribution in the human brain, based on a large database of field maps acquired from different subjects, together with subject‐specific structural information from a quick localizer scan. The shimming performance of using the template‐based prediction is evaluated in comparison to a range of potential fast shimming methods. Results Static B0 shimming based on predicted field maps performed almost as well as shimming based on individually measured field maps. In experimental evaluations at 7 T, the proposed approach yielded a residual field standard deviation in the brain of on average 59 Hz, compared with 50 Hz using measured field maps and 176 Hz using no subject‐specific shim. Conclusions This work demonstrates that shimming based on predicted field maps is feasible. The field map prediction accuracy could potentially be further improved by generating the template from a subset of subjects, based on parameters such as head rotation and body mass index. Magn Reson Med 80:171–180, 2018. © 2017 The Authors Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. PMID:29193340

Crystallographic and Computational Analyses of AUUCU Repeating RNA That Causes Spinocerebellar Ataxia Type 10 (SCA10).

PubMed

Park, HaJeung; González, Àlex L; Yildirim, Ilyas; Tran, Tuan; Lohman, Jeremy R; Fang, Pengfei; Guo, Min; Disney, Matthew D

2015-06-23

Spinocerebellar ataxia type 10 (SCA10) is caused by a pentanucleotide repeat expansion of r(AUUCU) within intron 9 of the ATXN10 pre-mRNA. The RNA causes disease by a gain-of-function mechanism in which it inactivates proteins involved in RNA biogenesis. Spectroscopic studies showed that r(AUUCU) repeats form a hairpin structure; however, there were no high-resolution structural models prior to this work. Herein, we report the first crystal structure of model r(AUUCU) repeats refined to 2.8 Å and analysis of the structure via molecular dynamics simulations. The r(AUUCU) tracts adopt an overall A-form geometry in which 3 × 3 nucleotide (5')UCU(3')/(3')UCU(5') internal loops are closed by AU pairs. Helical parameters of the refined structure as well as the corresponding electron density map on the crystallographic model reflect dynamic features of the internal loop. The computational analyses captured dynamic motion of the loop closing pairs, which can form single-stranded conformations with relatively low energies. Overall, the results presented here suggest the possibility for r(AUUCU) repeats to form metastable A-from structures, which can rearrange into single-stranded conformations and attract proteins such as heterogeneous nuclear ribonucleoprotein K (hnRNP K). The information presented here may aid in the rational design of therapeutics targeting this RNA.

Crystallographic and Computational Analyses of AUUCU Repeating RNA That Causes Spinocerebellar Ataxia Type 10 (SCA10)

PubMed Central

Park, HaJeung; González, Àlex L.; Yildirim, Ilyas; Tran, Tuan; Lohman, Jeremy R.; Fang, Pengfei; Guo, Min; Disney, Matthew D.

2016-01-01

Spinocerebellar ataxia type 10 (SCA10) is caused by a pentanucleotide repeat expansion of r(AUUCU) within intron 9 of the ATXN10 pre-mRNA. The RNA causes disease by a gain-of-function mechanism in which it inactivates proteins involved in RNA biogenesis. Spectroscopic studies showed that r(AUUCU) repeats form a hairpin structure; however, there were no high-resolution structural models prior to this work. Herein, we report the first crystal structure of model r(AUUCU) repeats refined to 2.8 Å and analysis of the structure via molecular dynamics simulations. The r(AUUCU) tracts adopt an overall A-form geometry in which 3 × 3 nucleotide 5′UCU3′/3′UCU5′ internal loops are closed by AU pairs. Helical parameters of the refined structure as well as the corresponding electron density map on the crystallographic model reflect dynamic features of the internal loop. The computational analyses captured dynamic motion of the loop closing pairs, which can form single-stranded conformations with relatively low energies. Overall, the results presented here suggest the possibility for r(AUUCU) repeats to form metastable A-from structures, which can rearrange into single-stranded conformations and attract proteins such as heterogeneous nuclear ribonucleoprotein K (hnRNP K). The information presented here may aid in the rational design of therapeutics targeting this RNA. PMID:26039897

Spectral flow as a map between N = (2 , 0)-models

NASA Astrophysics Data System (ADS)

Athanasopoulos, P.; Faraggi, A. E.; Gepner, D.

2014-07-01

The space of (2 , 0) models is of particular interest among all heterotic-string models because it includes the models with the minimal SO (10) unification structure, which is well motivated by the Standard Model of particle physics data. The fermionic Z2 ×Z2 heterotic-string models revealed the existence of a new symmetry in the space of string configurations under the exchange of spinors and vectors of the SO (10) GUT group, dubbed spinor-vector duality. In this paper we generalize this idea to arbitrary internal rational conformal field theories (RCFTs). We explain how the spectral flow operator normally acting within a general (2 , 2) theory can be used as a map between (2 , 0) models. We describe the details, give an example and propose more simple currents that can be used in a similar way.

Aeroelastic Flutter Behavior of Cantilever within a Nozzle-Diffuser Geometry

NASA Astrophysics Data System (ADS)

Tosi, Luis Phillipe; Colonius, Tim; Sherrit, Stewart; Lee, Hyeong Jae

2015-11-01

Aeroelastic flutter arises when the motion of a structure and its surrounding flowing fluid are coupled in a constructive manner, causing large amplitudes of vibration in the immersed solid. A cantilevered beam in axial flow within a nozzle-diffuser geometry exhibits interesting resonance behavior that presents good prospects for internal flow energy harvesting. Different modes can be excited as a function of throat velocity, nozzle geometry, fluid and cantilever material parameters. This work explores the relationship between the aeroelastic flutter instability boundaries and relevant non-dimensional parameters via experiments. Results suggest that for a linear expansion diffuser geometry, a non-dimensional stiffness, non-dimensional mass, and non-dimensional throat size are the critical parameters in mapping the instability. This map can serve as a guide to future work concerning possible electrical output and failure prediction in energy harvesters.

Noninvasive Assessment of Oxygen Extraction Fraction in Chronic Ischemia Using Quantitative Susceptibility Mapping at 7 Tesla.

PubMed

Uwano, Ikuko; Kudo, Kohsuke; Sato, Ryota; Ogasawara, Kuniaki; Kameda, Hiroyuki; Nomura, Jun-Ichi; Mori, Futoshi; Yamashita, Fumio; Ito, Kenji; Yoshioka, Kunihiro; Sasaki, Makoto

2017-08-01

The oxygen extraction fraction (OEF) is an effective metric to evaluate metabolic reserve in chronic ischemia. However, OEF is considered to be accurately measured only when using positron emission tomography (PET). Thus, we investigated whether OEF maps generated by magnetic resonance quantitative susceptibility mapping (QSM) at 7 Tesla enabled detection of OEF changes when compared with those obtained with PET. Forty-one patients with chronic stenosis/occlusion of the unilateral internal carotid artery or middle cerebral artery were examined using 7 Tesla-MRI and PET scanners. QSM images were obtained from 3-dimensional T2*-weighted images, using a multiple dipole-inversion algorithm. OEF maps were generated based on susceptibility differences between venous structures and brain tissues on QSM images. OEF ratios of the ipsilateral middle cerebral artery territory against the contralateral side were calculated on the QSM-OEF and PET-OEF images, using an anatomic template. The OEF ratio in the middle cerebral artery territory showed significant correlations between QSM-OEF and PET-OEF maps ( r =0.69; P <0.001), especially in patients with a substantial increase in the PET-OEF ratio of 1.09 ( r =0.79; P =0.004), although showing significant systematic biases for the agreements. An increased QSM-OEF ratio of >1.09, as determined by receiver operating characteristic analysis, showed a sensitivity and specificity of 0.82 and 0.86, respectively, for the substantial increase in the PET-OEF ratio. Absolute QSM-OEF values were significantly correlated with PET-OEF values in the patients with increased PET-OEF. OEF ratios on QSM-OEF images at 7 Tesla showed a good correlation with those on PET-OEF images in patients with unilateral steno-occlusive internal carotid artery/middle cerebral artery lesions, suggesting that noninvasive OEF measurement by MRI can be a substitute for PET. © 2017 American Heart Association, Inc.

76 FR 21939 - Noise Exposure Map; Receipt of Noise Compatibility Program and Request for Review; Lambert-St...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-19

... Compatibility Program and Request for Review; Lambert-St. Louis International Airport, St. Louis, MO AGENCY...) announces its determination that the noise exposure maps submitted by the St. Louis Airport Authority for the Lambert-St. Louis International Airport under the provisions of 49 U.S.C. 47501 et seq. (Aviation...

76 FR 60962 - Noise Exposure Map Update for Buffalo Niagara International Airport, Buffalo, NY

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-30

... International Airport, under the provisions of 49 U.S.C. 47501 et seq. (Aviation Safety and Noise Abatement Act...''), effective September 20, 2011. Under 49 U.S.C. section 47503 of the Aviation Safety and Noise Abatement Act... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Noise Exposure Map Update for Buffalo...

NOAA Office of Exploration and Research > About OER > Organization > Map of

Science.gov Websites

About OER Overview Organization Guiding Documents Organizational Structure Map of Staff and Affiliate Overview Website & Social Media News Room OER Symposium Guiding Documents Organizational Structure Map About OER Overview Organization Guiding Documents Organizational Structure Map of Staff and Affiliate

International Map Year: Results and Implications

NASA Astrophysics Data System (ADS)

Rystedt, Bengt; Ormeling, Ferjan; Buckley, Aileen; Coetzee, Serena; Voženilek, Vit; Fairbairn, David; Kagawa, Ayako

2018-05-01

IMY was a worldwide celebration of maps and their unique role in our world. Supported by the United Nations, IMY provides opportunities to demonstrate, follow, and get involved in the art, science, and technology of making and using maps and geographic information. International Map Year (IMY) started in Paris 2011 when the General Assembly of the International Cartographic Association (ICA) asked the ICA Executive Committee (EC) to follow up on the proposal given in a motion from the Swedish Cartographic Society. An IMY Working Group (WG) was constituted - it defined the IMY goals and the activities required to reach them, and it proposed a suitable time period for the IMY to the ICA EC. IMY commenced in August 2015 and ended in December 2016. The success of IMY was dependent on all member nations of the ICA participating in an effort to broaden the knowledge of cartography and geographic information in society in general, especially among citizens and school children. Member nations of the ICA were responsible for organizing IMY activities, such as a national Map Day, through national IMY committees tasked to engage national organizations and spearheading collaboration. The IMY WG set up an IMY web site with general information on IMY, guidelines for how to organize Map Days, suggestions relating to activities aimed at general map awareness, and more. The web site also provides access to the electronic book The World of Maps, which has been translated from English into five other languages.

Optimal contact definition for reconstruction of contact maps.

PubMed

Duarte, Jose M; Sathyapriya, Rajagopal; Stehr, Henning; Filippis, Ioannis; Lappe, Michael

2010-05-27

Contact maps have been extensively used as a simplified representation of protein structures. They capture most important features of a protein's fold, being preferred by a number of researchers for the description and study of protein structures. Inspired by the model's simplicity many groups have dedicated a considerable amount of effort towards contact prediction as a proxy for protein structure prediction. However a contact map's biological interest is subject to the availability of reliable methods for the 3-dimensional reconstruction of the structure. We use an implementation of the well-known distance geometry protocol to build realistic protein 3-dimensional models from contact maps, performing an extensive exploration of many of the parameters involved in the reconstruction process. We try to address the questions: a) to what accuracy does a contact map represent its corresponding 3D structure, b) what is the best contact map representation with regard to reconstructability and c) what is the effect of partial or inaccurate contact information on the 3D structure recovery. Our results suggest that contact maps derived from the application of a distance cutoff of 9 to 11A around the Cbeta atoms constitute the most accurate representation of the 3D structure. The reconstruction process does not provide a single solution to the problem but rather an ensemble of conformations that are within 2A RMSD of the crystal structure and with lower values for the pairwise average ensemble RMSD. Interestingly it is still possible to recover a structure with partial contact information, although wrong contacts can lead to dramatic loss in reconstruction fidelity. Thus contact maps represent a valid approximation to the structures with an accuracy comparable to that of experimental methods. The optimal contact definitions constitute key guidelines for methods based on contact maps such as structure prediction through contacts and structural alignments based on maximum contact map overlap.

Optimal contact definition for reconstruction of Contact Maps

PubMed Central

2010-01-01

Background Contact maps have been extensively used as a simplified representation of protein structures. They capture most important features of a protein's fold, being preferred by a number of researchers for the description and study of protein structures. Inspired by the model's simplicity many groups have dedicated a considerable amount of effort towards contact prediction as a proxy for protein structure prediction. However a contact map's biological interest is subject to the availability of reliable methods for the 3-dimensional reconstruction of the structure. Results We use an implementation of the well-known distance geometry protocol to build realistic protein 3-dimensional models from contact maps, performing an extensive exploration of many of the parameters involved in the reconstruction process. We try to address the questions: a) to what accuracy does a contact map represent its corresponding 3D structure, b) what is the best contact map representation with regard to reconstructability and c) what is the effect of partial or inaccurate contact information on the 3D structure recovery. Our results suggest that contact maps derived from the application of a distance cutoff of 9 to 11Å around the Cβ atoms constitute the most accurate representation of the 3D structure. The reconstruction process does not provide a single solution to the problem but rather an ensemble of conformations that are within 2Å RMSD of the crystal structure and with lower values for the pairwise average ensemble RMSD. Interestingly it is still possible to recover a structure with partial contact information, although wrong contacts can lead to dramatic loss in reconstruction fidelity. Conclusions Thus contact maps represent a valid approximation to the structures with an accuracy comparable to that of experimental methods. The optimal contact definitions constitute key guidelines for methods based on contact maps such as structure prediction through contacts and structural alignments based on maximum contact map overlap. PMID:20507547

Development and validation of a Housing First fidelity survey.

PubMed

Gilmer, Todd P; Stefancic, Ana; Sklar, Marisa; Tsemberis, Sam

2013-09-01

Programs that use the Housing First model are being implemented throughout the United States and internationally. The authors describe the development and validation of a Housing First fidelity survey. A 46-item survey was developed to measure fidelity across five domains: housing process and structure, separation of housing and services, service philosophy, service array, and team structure. The survey was administered to staff and clients of 93 supported-housing programs in California. Exploratory and confirmatory factor analyses were used to identify the items and model structure that best fit the data. Sixteen items were retained in a two-factor model, one related to approach to housing, separation of housing and services, and service philosophy and one related to service array and team structure. Our survey mapped program practices by using a common metric that captured variation in fidelity to Housing First across a large-scale implementation of supported-housing programs.

The structure of Escherichia coli signal recognition particle revealed by scanning transmission electron microscopy.

PubMed

Mainprize, Iain L; Beniac, Daniel R; Falkovskaia, Elena; Cleverley, Robert M; Gierasch, Lila M; Ottensmeyer, F Peter; Andrews, David W

2006-12-01

Structural studies on various domains of the ribonucleoprotein signal recognition particle (SRP) have not converged on a single complete structure of bacterial SRP consistent with the biochemistry of the particle. We obtained a three-dimensional structure for Escherichia coli SRP by cryoscanning transmission electron microscopy and mapped the internal RNA by electron spectroscopic imaging. Crystallographic data were fit into the SRP reconstruction, and although the resulting model differed from previous models, they could be rationalized by movement through an interdomain linker of Ffh, the protein component of SRP. Fluorescence resonance energy transfer experiments determined interdomain distances that were consistent with our model of SRP. Docking our model onto the bacterial ribosome suggests a mechanism for signal recognition involving interdomain movement of Ffh into and out of the nascent chain exit site and suggests how SRP could interact and/or compete with the ribosome-bound chaperone, trigger factor, for a nascent chain during translation.

Report of the Fourth International Workshop on human X chromosome mapping 1993

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schlessinger, D.; Mandel, J.L.; Monaco, A.P.

1993-12-31

Vigorous interactive efforts by the X chromosome community have led to accelerated mapping in the last six months. Seventy-five participants from 12 countries around the globe contributed progress reports to the Fourth International X Chromosome Workshop, at St. Louis, MO, May 9-12, 1993. It became clear that well over half the chromosome is now covered by YAC contigs that are being extended, verified, and aligned by their content of STSs and other markers placed by cytogenetic or linkage mapping techniques. The major aim of the workshop was to assemble the consensus map that appears in this report, summarizing both consensusmore » order and YAC contig information.« less

Structure contour map of the greater Green River basin, Wyoming, Colorado, and Utah

USGS Publications Warehouse

Lickus, M.R.; Law, B.E.

1988-01-01

The Greater Green River basin of Wyoming, Colorado, and Utah contains five basins and associated major uplifts (fig. 1). Published structure maps of the region have commonly used the top of the Lower Cretaceous Dakota Sandstone as a structural datum (Petroleum Ownership Map Company (POMCO), 1984; Rocky Mountain Association of Geologists, 1972). However, because relatively few wells in this area penetrate the Dakota, the Dakota structural datum has to be constructed by projecting down from shallower wells. Extrapolating in this manner may produce errors in the map. The primary purpose of this report is to present a more reliable structure contour map of the Greater Green River basin based on datums that are penetrated by many wells. The final map shows the large- to small-scale structures present in the Greater Green River basin. The availability of subsurface control and the map scale determined whether or not a structural feature was included on the map. In general, large structures such as the Moxa arch, Pinedale anticline, and other large folds were placed on the map based solely on the structure contours. In comparison, smaller folds and some faults were placed on the map based on structure contours and other reports (Bader 1987; Bradley 1961; Love and Christiansen, 1985; McDonald, 1975; Roehler, 1979; Wyoming Geological Association Oil and Gas Symposium Committee, 1979). State geologic maps and other reports were used to position basin margin faults (Bryant, 1985; Gries, 1983a, b; Hansen 1986; Hintze, 1980; Love and Christiansen, 1985; Tweto, 1979, 1983). In addition, an interpreted east-west-trending regional seismic line by Garing and Tainter (1985), which shows the basin configuration in cross-section, was helpful in locating buried faults, such as the high-angle reverse or thrust fault along the west flank of the Rock Springs uplift.

Internal structure, fault rocks, and inferences regarding deformation, fluid flow, and mineralization in the seismogenic Stillwater normal fault, Dixie Valley, Nevada

USGS Publications Warehouse

Caine, Jonathan S.; Bruhn, R.L.; Forster, C.B.

2010-01-01

Outcrop mapping and fault-rock characterization of the Stillwater normal fault zone in Dixie Valley, Nevada are used to document and interpret ancient hydrothermal fluid flow and its possible relationship to seismic deformation. The fault zone is composed of distinct structural and hydrogeological components. Previous work on the fault rocks is extended to the map scale where a distinctive fault core shows a spectrum of different fault-related breccias. These include predominantly clast-supported breccias with angular clasts that are cut by zones containing breccias with rounded clasts that are also clast supported. These are further cut by breccias that are predominantly matrix supported with angular and rounded clasts. The fault-core breccias are surrounded by a heterogeneously fractured damage zone. Breccias are bounded between major, silicified slip surfaces, forming large pod-like structures, systematically oriented with long axes parallel to slip. Matrix-supported breccias have multiply brecciated, angular and rounded clasts revealing episodic deformation and fluid flow. These breccias have a quartz-rich matrix with microcrystalline anhedral, equant, and pervasively conformable mosaic texture. The breccia pods are interpreted to have formed by decompression boiling and rapid precipitation of hydrothermal fluids whose flow was induced by coseismic, hybrid dilatant-shear deformation and hydraulic connection to a geothermal reservoir. The addition of hydrothermal silica cement localized in the core at the map scale causes fault-zone widening, local sealing, and mechanical heterogeneities that impact the evolution of the fault zone throughout the seismic cycle. ?? 2010.

NREL: International Activities - Afghanistan Resource Maps

Science.gov Websites

facilities, load centers, terrain conditions, and land use. The high-resolution (1-km) annual wind power maps . The high-resolution (10-km) annual and seasonal solar resource maps were developed using weather -km Resolution Annual Maps (Direct) Low-Res (JPG 104 KB) | High-Res (ZIP 330 KB) 40-km Resolution

Frequency content of sea surface height variability from internal gravity waves to mesoscale eddies

NASA Astrophysics Data System (ADS)

Savage, Anna C.; Arbic, Brian K.; Richman, James G.; Shriver, Jay F.; Alford, Matthew H.; Buijsman, Maarten C.; Thomas Farrar, J.; Sharma, Hari; Voet, Gunnar; Wallcraft, Alan J.; Zamudio, Luis

2017-03-01

High horizontal-resolution (1/12.5° and 1/25°) 41-layer global simulations of the HYbrid Coordinate Ocean Model (HYCOM), forced by both atmospheric fields and the astronomical tidal potential, are used to construct global maps of sea surface height (SSH) variability. The HYCOM output is separated into steric and nonsteric and into subtidal, diurnal, semidiurnal, and supertidal frequency bands. The model SSH output is compared to two data sets that offer some geographical coverage and that also cover a wide range of frequencies—a set of 351 tide gauges that measure full SSH and a set of 14 in situ vertical profilers from which steric SSH can be calculated. Three of the global maps are of interest in planning for the upcoming Surface Water and Ocean Topography (SWOT) two-dimensional swath altimeter mission: (1) maps of the total and (2) nonstationary internal tidal signal (the latter calculated after removing the stationary internal tidal signal via harmonic analysis), with an average variance of 1.05 and 0.43 cm2, respectively, for the semidiurnal band, and (3) a map of the steric supertidal contributions, which are dominated by the internal gravity wave continuum, with an average variance of 0.15 cm2. Stationary internal tides (which are predictable), nonstationary internal tides (which will be harder to predict), and nontidal internal gravity waves (which will be very difficult to predict) may all be important sources of high-frequency "noise" that could mask lower frequency phenomena in SSH measurements made by the SWOT mission.

Coming To Know: The Role of the Concept Map--Mirror, Assistant, Master?

ERIC Educational Resources Information Center

McAleese, Ray

This paper explains the process of creating and managing concept maps, using reflection as a focus for its argument. Section 1, What is a Concept Map?, highlights the background and definition of concept mapping, explains how maps signify virtual conceptual structures, looks at structural knowledge, provides an example of a concept map, and…

Concept Map Structure, Gender and Teaching Methods: An Investigation of Students' Science Learning

ERIC Educational Resources Information Center

Gerstner, Sabine; Bogner, Franz X.

2009-01-01

Background: This study deals with the application of concept mapping to the teaching and learning of a science topic with secondary school students in Germany. Purpose: The main research questions were: (1) Do different teaching approaches affect concept map structure or students' learning success? (2) Is the structure of concept maps influenced…

Iconicity as structure mapping

PubMed Central

Emmorey, Karen

2014-01-01

Linguistic and psycholinguistic evidence is presented to support the use of structure-mapping theory as a framework for understanding effects of iconicity on sign language grammar and processing. The existence of structured mappings between phonological form and semantic mental representations has been shown to explain the nature of metaphor and pronominal anaphora in sign languages. With respect to processing, it is argued that psycholinguistic effects of iconicity may only be observed when the task specifically taps into such structured mappings. In addition, language acquisition effects may only be observed when the relevant cognitive abilities are in place (e.g. the ability to make structural comparisons) and when the relevant conceptual knowledge has been acquired (i.e. information key to processing the iconic mapping). Finally, it is suggested that iconicity is better understood as a structured mapping between two mental representations than as a link between linguistic form and human experience. PMID:25092669

GRAIL TCM-5 Go/No-Go: Developing Lunar Orbit Insertion (LOI) Criteria

NASA Technical Reports Server (NTRS)

Chung, Min-Kun J.

2013-01-01

The Gravity Recovery and Interior Laboratory (GRAIL) mission successfully completed mapping the Moon's gravity field to an unprecedented level for a better understanding of the internal structure and thermal evolution of the Moon. The mission success was critically dependent on the success of the Lunar Orbit Insertion (LOI). In this paper we establish a set of LOI criteria to meet all the requirements and we use these criteria to establish Go/No-Go boundaries of the last, statistical Trajectory Correction Maneuvers (TCM-5s) for operations.

A study of morphology, provenance, and movement of desert sand seas in Africa, Asia, and Australia

NASA Technical Reports Server (NTRS)

Mckee, E. D.; Breed, C. S.

1973-01-01

A description and classification of major types of sand seas on the basis of morphological pattern and lineation are discussed. The steps involved in analyzing the patterns of deposits on ERTS-1 imagery, where the visible forms are mostly dune complexes rather than individual dunes are outlined. After completion of thematic maps portraying the pattern and lineation of the sand bodies, data on directions and intensity of prevailing and other winds are plotted on corresponding bases, as a preliminary to determination of internal structures through ground truth.

Zombie projects, negative networks, and multigenerational science: The temporality of the International Map of the World.

PubMed

Rankin, William

2017-06-01

The International Map of the World was a hugely ambitious scheme to create standardized maps of the entire world. It was first proposed in 1891 and remained a going concern until 1986. Over the course of the project's official life, nearly every country in the world took part, and map sheets were published showing all but a few areas of the planet. But the project ended quite unceremoniously, repudiated by cartographers and mapping institutions alike, and it is now remembered as a 'sad story' of network failure. How can we evaluate this kind of sprawling, multigenerational project? In order to move beyond practitioners' (and historians') habit of summarizing the entire endeavor using the blunt categories of success and failure, I propose a more temporally aware reading, one that both disaggregates the (persistent) project from the (always changing) network and sees project and network as invertible, with the possibility of zombie projects and negative networks that can remain robust even when disconnected from their original goals. I therefore see the abandonment of the International Map of the World as resulting from vigorous collaboration and new norms in cartography, not from lack of cooperation or other resources. New categories are required for analyzing science over the long durée.

Implementing Dementia Care Mapping to develop person-centred care: results of a process evaluation within the Leben-QD II trial.

PubMed

Quasdorf, Tina; Riesner, Christine; Dichter, Martin Nikolaus; Dortmann, Olga; Bartholomeyczik, Sabine; Halek, Margareta

2017-03-01

To evaluate Dementia Care Mapping implementation in nursing homes. Dementia Care Mapping, an internationally applied method for supporting and enhancing person-centred care for people with dementia, must be successfully implemented into care practice for its effective use. Various factors influence the implementation of complex interventions such as Dementia Care Mapping; few studies have examined the specific factors influencing Dementia Care Mapping implementation. A convergent parallel mixed-methods design embedded in a quasi-experimental trial was used to assess Dementia Care Mapping implementation success and influential factors. From 2011-2013, nine nursing units in nine different nursing homes implemented either Dementia Care Mapping (n = 6) or a periodic quality of life measurement using the dementia-specific instrument QUALIDEM (n = 3). Diverse data (interviews, n = 27; questionnaires, n = 112; resident records, n = 81; and process documents) were collected. Each data set was separately analysed and then merged to comprehensively portray the implementation process. Four nursing units implemented the particular intervention without deviating from the preplanned intervention. Translating Dementia Care Mapping results into practice was challenging. Necessary organisational preconditions for Dementia Care Mapping implementation included well-functioning networks, a dementia-friendly culture and flexible organisational structures. Involved individuals' positive attitudes towards Dementia Care Mapping also facilitated implementation. Precisely planning the intervention and its implementation, recruiting champions who supported Dementia Care Mapping implementation and having well-qualified, experienced project coordinators were essential to the implementation process. For successful Dementia Care Mapping implementation, it must be embedded in a systematic implementation strategy considering the specific setting. Organisational preconditions may need to be developed before Dementia Care Mapping implementation. Necessary steps may include team building, developing and realising a person-centred care-based mission statement or educating staff regarding general dementia care. The implementation strategy may include attracting and involving individuals on different hierarchical levels in Dementia Care Mapping implementation and supporting staff to translate Dementia Care Mapping results into practice. The identified facilitating factors can guide Dementia Care Mapping implementation strategy development. © 2016 John Wiley & Sons Ltd.

Likelihood-based modification of experimental crystal structure electron density maps

DOEpatents

Terwilliger, Thomas C [Sante Fe, NM

2005-04-16

A maximum-likelihood method for improves an electron density map of an experimental crystal structure. A likelihood of a set of structure factors {F.sub.h } is formed for the experimental crystal structure as (1) the likelihood of having obtained an observed set of structure factors {F.sub.h.sup.OBS } if structure factor set {F.sub.h } was correct, and (2) the likelihood that an electron density map resulting from {F.sub.h } is consistent with selected prior knowledge about the experimental crystal structure. The set of structure factors {F.sub.h } is then adjusted to maximize the likelihood of {F.sub.h } for the experimental crystal structure. An improved electron density map is constructed with the maximized structure factors.

An evolving effective stress approach to anisotropic distortional hardening

DOE PAGES

Lester, B. T.; Scherzinger, W. M.

2018-03-11

A new yield surface with an evolving effective stress definition is proposed for consistently and efficiently describing anisotropic distortional hardening. Specifically, a new internal state variable is introduced to capture the thermodynamic evolution between different effective stress definitions. The corresponding yield surface and evolution equations of the internal variables are derived from thermodynamic considerations enabling satisfaction of the second law. A closest point projection return mapping algorithm for the proposed model is formulated and implemented for use in finite element analyses. Finally, select constitutive and larger scale boundary value problems are solved to explore the capabilities of the model andmore » examine the impact of distortional hardening on constitutive and structural responses. Importantly, these simulations demonstrate the tractability of the proposed formulation in investigating large-scale problems of interest.« less

An evolving effective stress approach to anisotropic distortional hardening

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lester, B. T.; Scherzinger, W. M.

A new yield surface with an evolving effective stress definition is proposed for consistently and efficiently describing anisotropic distortional hardening. Specifically, a new internal state variable is introduced to capture the thermodynamic evolution between different effective stress definitions. The corresponding yield surface and evolution equations of the internal variables are derived from thermodynamic considerations enabling satisfaction of the second law. A closest point projection return mapping algorithm for the proposed model is formulated and implemented for use in finite element analyses. Finally, select constitutive and larger scale boundary value problems are solved to explore the capabilities of the model andmore » examine the impact of distortional hardening on constitutive and structural responses. Importantly, these simulations demonstrate the tractability of the proposed formulation in investigating large-scale problems of interest.« less

Mapping Future Research in Disabilities--Research Initiatives in Intellectual Disabilities in India: Report of a National Interdisciplinary Meeting

ERIC Educational Resources Information Center

Cohen, Libby; Brown, Roy I.

2012-01-01

A meeting organized under the auspices of the International Association for the Scientific Study of Intellectual Disabilities (IASSID) Academy on Education, Teaching and Research was held in March 2011 at the India International Centre in New Delhi, India, with the explicit purpose of helping establish a road map for future research in…

Sequence-structure mapping errors in the PDB: OB-fold domains

PubMed Central

Venclovas, Česlovas; Ginalski, Krzysztof; Kang, Chulhee

2004-01-01

The Protein Data Bank (PDB) is the single most important repository of structural data for proteins and other biologically relevant molecules. Therefore, it is critically important to keep the PDB data, as much as possible, error-free. In this study, we have analyzed PDB crystal structures possessing oligonucleotide/oligosaccharide binding (OB)-fold, one of the highly populated folds, for the presence of sequence-structure mapping errors. Using energy-based structure quality assessment coupled with sequence analyses, we have found that there are at least five OB-structures in the PDB that have regions where sequences have been incorrectly mapped onto the structure. We have demonstrated that the combination of these computation techniques is effective not only in detecting sequence-structure mapping errors, but also in providing guidance to correct them. Namely, we have used results of computational analysis to direct a revision of X-ray data for one of the PDB entries containing a fairly inconspicuous sequence-structure mapping error. The revised structure has been deposited with the PDB. We suggest use of computational energy assessment and sequence analysis techniques to facilitate structure determination when homologs having known structure are available to use as a reference. Such computational analysis may be useful in either guiding the sequence-structure assignment process or verifying the sequence mapping within poorly defined regions. PMID:15133161

Documentation for the Southeast Asia seismic hazard maps

USGS Publications Warehouse

Petersen, Mark; Harmsen, Stephen; Mueller, Charles; Haller, Kathleen; Dewey, James; Luco, Nicolas; Crone, Anthony; Lidke, David; Rukstales, Kenneth

2007-01-01

The U.S. Geological Survey (USGS) Southeast Asia Seismic Hazard Project originated in response to the 26 December 2004 Sumatra earthquake (M9.2) and the resulting tsunami that caused significant casualties and economic losses in Indonesia, Thailand, Malaysia, India, Sri Lanka, and the Maldives. During the course of this project, several great earthquakes ruptured subduction zones along the southern coast of Indonesia (fig. 1) causing additional structural damage and casualties in nearby communities. Future structural damage and societal losses from large earthquakes can be mitigated by providing an advance warning of tsunamis and introducing seismic hazard provisions in building codes that allow buildings and structures to withstand strong ground shaking associated with anticipated earthquakes. The Southeast Asia Seismic Hazard Project was funded through a United States Agency for International Development (USAID)—Indian Ocean Tsunami Warning System to develop seismic hazard maps that would assist engineers in designing buildings that will resist earthquake strong ground shaking. An important objective of this project was to discuss regional hazard issues with building code officials, scientists, and engineers in Thailand, Malaysia, and Indonesia. The code communities have been receptive to these discussions and are considering updating the Thailand and Indonesia building codes to incorporate new information (for example, see notes from Professor Panitan Lukkunaprasit, Chulalongkorn University in Appendix A).

Aeromagnetic map compilation: Procedures for merging and an example from Washington

USGS Publications Warehouse

Finn, C.

1999-01-01

Rocks in Antarctica and offshore have widely diverse magnetic properties. Consequently, aeromagnetic data collected there can improve knowledge of the geologic, tectonic and geothermal characteristics of the region. Aeromagnetic data can map concealed structures such as faults, folds and dikes, ascertain basin thickness and locate buried volcanic, as well as some intrusive and metamorphic rocks. Gridded, composite data sets allow a view of continental-scale trends that individual data sets do not provide and link widely-separated areas of outcrop and disparate geologic studies. Individual magnetic surveys must be processed so that they match adjacent surveys prior to merging. A consistent representation of the Earth's magnetic field (International Geomagnetic Reference Field (IGRF)) must be removed from each data set. All data sets need to be analytically continued to the same flight elevation with their datums shifted to match adjacent data. I advocate minimal processing to best represent the individual surveys in the merged compilation. An example of a compilation of aeromagnetic surveys from Washington illustrates the utility of aeromagnetic maps for providing synoptic views of regional tectonic features.

Utilization of Google enterprise tools to georeference survey data among hard-to-reach groups: strategic application in international settings.

PubMed

Beletsky, Leo; Arredondo, Jaime; Werb, Dan; Vera, Alicia; Abramovitz, Daniela; Amon, Joseph J; Brouwer, Kimberly C; Strathdee, Steffanie A; Gaines, Tommi L

2016-07-28

As geospatial data have become increasingly integral to health and human rights research, their collection using formal address designations or paper maps has been complicated by numerous factors, including poor cartographic literacy, nomenclature imprecision, and human error. As part of a longitudinal study of people who inject drugs in Tijuana, Mexico, respondents were prompted to georeference specific experiences. At baseline, only about one third of the 737 participants were native to Tijuana, underscoring prevalence of migration/deportation experience. Areas frequented typically represented locations with no street address (e.g. informal encampments). Through web-based cartographic technology and participatory mapping, this study was able to overcome the use of vernacular names and difficulties mapping liminal spaces in generating georeferenced data points that were subsequently analyzed in other research. Integrating low-threshold virtual navigation as part of data collection can enhance investigations of mobile populations, informal settlements, and other locations in research into structural production of health at low- or no cost. However, further research into user experience is warranted.

Hydrogeological Characterization of the Upper Camp Bird III Rock Glacier in the San Juan Mountains, Colorado Using Electromagnetic Induction

NASA Astrophysics Data System (ADS)

Granados-Aguilar, R.; Giardino, J. R.; Everett, M. E.; Pondthai, P.; Ramsey, C. E.; Mmasa, D.; Witek, M.; Rodriguez, R.

2017-12-01

Global change is the set of variations in environmental conditions that significantly impact the Earth systems. Climate, sea level, land-use/land-cover, and atmospheric composition changes are the most recognized environmental global changes. Impacts of climatic variability can include decreased rainfall, snowpack, shorter snow seasons, and changes in the timing, frequency, and intensity of precipitation events in some areas of the world, whereas other regions can suffer from the opposite effects leading to events such as landslides, flooding and extraordinary snowfall. The proposed research intends to provide a characterization of the internal structure, including water storages, pathways, and thresholds, as well as an estimation of the volume of ice stored within a rock glacier to evaluate its potential as a freshwater resources. The area of study corresponds to the third level of Camp Bird Mine in Ouray, Colorado. The tongue-shaped active rock glacier of interest, Upper Camp Bird III, has not been previously studied in detail. The predominant lithologies in the study area are Mesozoic and Cenozoic. Orogenic events caused alteration of sedimentary and intrusive igneous rock as mineral rich, hydrothermal fluids deposited economically valuable minerals in the region. Traditional geological and geomorphological mapping techniques will be complemented with the use of unmanned aerial vehicles (UAV). To obtain a detailed representation of the internal structure and determine the boundaries between resistive (rocks, sediment, and ice) and conductive materials (water and ore deposits) of the rock glacier, time-domain and frequency-domain methods will be implemented. The G-TEM by Geonics Ltd. is an innovative controlled-source time-domain electromagnetic induction system. Using the G-TEM, the distribution of electrical conductivity in the subsurface can be mapped in order to characterize the internal structure of the rock glacier from 5-10 m depth and below. The EM Profiler is a frequency-domain electromagnetic induction system that will be used for the investigation of the uppermost layers of the rock glacier. For the proposed research, the use of two different systems will provide continuity across the data sets and will help validate the measurements recorded with the new equipment.

Relationship of geological and geothermal field properties: Midcontinent area, USA, an example

USGS Publications Warehouse

Forster, A.; Merriam, D.F.; Brower, J.C.

1993-01-01

Quantitative approaches to data analysis in the last decade have become important in basin modeling and mineral-resource estimation. The interrelation of geological, geophysical, geochemical, and geohydrological variables is important in adjusting a model to a real-world situation. Revealing the interdependences of variables can contribute in understanding the processes interacting in sedimentary basins. It is reasonably simple to compare spatial data of the same type but more difficult if different properties are involved. Statistical techniques, such as cluster analysis or principal components analysis, or some algebraic approaches can be used to ascertain the relations of standardized spatial data. In this example, structural configuration on five different stratigraphic horizons, one total sediment thickness map, and four maps of geothermal data were copared. As expected, the structural maps are highly related because all had undergone about the same deformation with differing degrees of intensity. The temperature gradients derived (1) from shallow borehole logging measurements under equilibrium conditions with the surrounding rock, and (2) from non-equilibrium bottom-hole temperatures (BHT) from deeper depths are mainly independent of each other. This was expected and confirmed also for the two temperature maps at 1000 ft which were constructed using both types of gradient values. Thus, it is evident that the use of a 2-point (BHT and surface temperature) straightline calculation of a mean temperature gradient gives different information about the geothermal regime than using gradients from temperatures logged under equilibrium conditions. Nevertheless, it is useful to determine to what a degree the larger dataset of nonequilibrium temperatures could reflect quantitative relationships to geologic conditions. Comparing all maps of geothermal information vs. the structural and the sediment thickness maps, it was determined that all correlations are moderately negative or slightly positive. These results are clearly shown by the cluster analysis and the principal components. Considering a close relationship between temperature and thermal conductivity of the sediments as observed for most of the Midcontinent area and relatively homogeneous heat-flow density conditions for the study area these results support the following assumptions: (1) undifferentiated geothermal gradients, computed from temperatures of different depth intervals and differing sediment properties, cannot contribute to an improved understanding of the temperature structure and its controls within the sedimentary cover, and (2) the quantitative approach of revealing such relations needs refined datasets of temperature information valid for the different depth levels or stratigraphic units. ?? 1993 International Association for Mathematical Geology.

Navigating 3D electron microscopy maps with EM-SURFER.

PubMed

Esquivel-Rodríguez, Juan; Xiong, Yi; Han, Xusi; Guang, Shuomeng; Christoffer, Charles; Kihara, Daisuke

2015-05-30

The Electron Microscopy DataBank (EMDB) is growing rapidly, accumulating biological structural data obtained mainly by electron microscopy and tomography, which are emerging techniques for determining large biomolecular complex and subcellular structures. Together with the Protein Data Bank (PDB), EMDB is becoming a fundamental resource of the tertiary structures of biological macromolecules. To take full advantage of this indispensable resource, the ability to search the database by structural similarity is essential. However, unlike high-resolution structures stored in PDB, methods for comparing low-resolution electron microscopy (EM) density maps in EMDB are not well established. We developed a computational method for efficiently searching low-resolution EM maps. The method uses a compact fingerprint representation of EM maps based on the 3D Zernike descriptor, which is derived from a mathematical series expansion for EM maps that are considered as 3D functions. The method is implemented in a web server named EM-SURFER, which allows users to search against the entire EMDB in real-time. EM-SURFER compares the global shapes of EM maps. Examples of search results from different types of query structures are discussed. We developed EM-SURFER, which retrieves structurally relevant matches for query EM maps from EMDB within seconds. The unique capability of EM-SURFER to detect 3D shape similarity of low-resolution EM maps should prove invaluable in structural biology.

Planck intermediate results. XLVIII. Disentangling Galactic dust emission and cosmic infrared background anisotropies

NASA Astrophysics Data System (ADS)

Planck Collaboration; Aghanim, N.; Ashdown, M.; Aumont, J.; Baccigalupi, C.; Ballardini, M.; Banday, A. J.; Barreiro, R. B.; Bartolo, N.; Basak, S.; Benabed, K.; Bernard, J.-P.; Bersanelli, M.; Bielewicz, P.; Bonavera, L.; Bond, J. R.; Borrill, J.; Bouchet, F. R.; Boulanger, F.; Burigana, C.; Calabrese, E.; Cardoso, J.-F.; Carron, J.; Chiang, H. C.; Colombo, L. P. L.; Comis, B.; Couchot, F.; Coulais, A.; Crill, B. P.; Curto, A.; Cuttaia, F.; de Bernardis, P.; de Zotti, G.; Delabrouille, J.; Di Valentino, E.; Dickinson, C.; Diego, J. M.; Doré, O.; Douspis, M.; Ducout, A.; Dupac, X.; Dusini, S.; Elsner, F.; Enßlin, T. A.; Eriksen, H. K.; Falgarone, E.; Fantaye, Y.; Finelli, F.; Forastieri, F.; Frailis, M.; Fraisse, A. A.; Franceschi, E.; Frolov, A.; Galeotta, S.; Galli, S.; Ganga, K.; Génova-Santos, R. T.; Gerbino, M.; Ghosh, T.; Giraud-Héraud, Y.; González-Nuevo, J.; Górski, K. M.; Gruppuso, A.; Gudmundsson, J. E.; Hansen, F. K.; Helou, G.; Henrot-Versillé, S.; Herranz, D.; Hivon, E.; Huang, Z.; Jaffe, A. H.; Jones, W. C.; Keihänen, E.; Keskitalo, R.; Kiiveri, K.; Kisner, T. S.; Krachmalnicoff, N.; Kunz, M.; Kurki-Suonio, H.; Lamarre, J.-M.; Langer, M.; Lasenby, A.; Lattanzi, M.; Lawrence, C. R.; Le Jeune, M.; Levrier, F.; Lilje, P. B.; Lilley, M.; Lindholm, V.; López-Caniego, M.; Ma, Y.-Z.; Macías-Pérez, J. F.; Maggio, G.; Maino, D.; Mandolesi, N.; Mangilli, A.; Maris, M.; Martin, P. G.; Martínez-González, E.; Matarrese, S.; Mauri, N.; McEwen, J. D.; Melchiorri, A.; Mennella, A.; Migliaccio, M.; Miville-Deschênes, M.-A.; Molinari, D.; Moneti, A.; Montier, L.; Morgante, G.; Moss, A.; Natoli, P.; Oxborrow, C. A.; Pagano, L.; Paoletti, D.; Patanchon, G.; Perdereau, O.; Perotto, L.; Pettorino, V.; Piacentini, F.; Plaszczynski, S.; Polastri, L.; Polenta, G.; Puget, J.-L.; Rachen, J. P.; Racine, B.; Reinecke, M.; Remazeilles, M.; Renzi, A.; Rocha, G.; Rosset, C.; Rossetti, M.; Roudier, G.; Rubiño-Martín, J. A.; Ruiz-Granados, B.; Salvati, L.; Sandri, M.; Savelainen, M.; Scott, D.; Sirignano, C.; Sirri, G.; Soler, J. D.; Spencer, L. D.; Suur-Uski, A.-S.; Tauber, J. A.; Tavagnacco, D.; Tenti, M.; Toffolatti, L.; Tomasi, M.; Tristram, M.; Trombetti, T.; Valiviita, J.; Van Tent, F.; Vielva, P.; Villa, F.; Vittorio, N.; Wandelt, B. D.; Wehus, I. K.; Zacchei, A.; Zonca, A.

2016-12-01

Using the Planck 2015 data release (PR2) temperature maps, we separate Galactic thermal dust emission from cosmic infrared background (CIB) anisotropies. For this purpose, we implement a specifically tailored component-separation method, the so-called generalized needlet internal linear combination (GNILC) method, which uses spatial information (the angular powerspectra) to disentangle the Galactic dust emission and CIB anisotropies. We produce significantly improved all-sky maps of Planck thermal dust emission, with reduced CIB contamination, at 353, 545, and 857 GHz. By reducing the CIB contamination of the thermal dust maps, we provide more accurate estimates of the local dust temperature and dust spectral index over the sky with reduced dispersion, especially at high Galactic latitudes above b = ±20°. We find that the dust temperature is T = (19.4 ± 1.3) K and the dust spectral index is β = 1.6 ± 0.1 averaged over the whole sky, while T = (19.4 ± 1.5) K and β = 1.6 ± 0.2 on 21% of the sky at high latitudes. Moreover, subtracting the new CIB-removed thermal dust maps from the CMB-removed Planck maps gives access to the CIB anisotropies over 60% of the sky at Galactic latitudes |b| > 20°. Because they are a significant improvement over previous Planck products, the GNILC maps are recommended for thermal dust science. The new CIB maps can be regarded as indirect tracers of the dark matter and they are recommended for exploring cross-correlations with lensing and large-scale structure optical surveys. The reconstructed GNILC thermal dust and CIB maps are delivered as Planck products.

Planck intermediate results: XLVIII. Disentangling Galactic dust emission and cosmic infrared background anisotropies

DOE PAGES

Aghanim, N.; Ashdown, M.; Aumont, J.; ...

2016-12-12

Using the Planck 2015 data release (PR2) temperature maps, we separate Galactic thermal dust emission from cosmic infrared background (CIB) anisotropies. For this purpose, we implement a specifically tailored component-separation method, the so-called generalized needlet internal linear combination (GNILC) method, which uses spatial information (the angular powerspectra) to disentangle the Galactic dust emission and CIB anisotropies. We produce significantly improved all-sky maps of Planck thermal dust emission, with reduced CIB contamination, at 353, 545, and 857 GHz. By reducing the CIB contamination of the thermal dust maps, we provide more accurate estimates of the local dust temperature and dust spectralmore » index over the sky with reduced dispersion, especially at high Galactic latitudes above b = ±20°. We find that the dust temperature is T = (19.4 ± 1.3) K and the dust spectral index is β = 1.6 ± 0.1 averaged over the whole sky, while T = (19.4 ± 1.5) K and β = 1.6 ± 0.2 on 21% of the sky at high latitudes. Moreover, subtracting the new CIB-removed thermal dust maps from the CMB-removed Planck maps gives access to the CIB anisotropies over 60% of the sky at Galactic latitudes |b| > 20°. Because they are a significant improvement over previous Planck products, the GNILC maps are recommended for thermal dust science. The new CIB maps can be regarded as indirect tracers of the dark matter and they are recommended for exploring cross-correlations with lensing and large-scale structure optical surveys. The reconstructed GNILC thermal dust and CIB maps are delivered as Planck products.« less

Planck intermediate results: XLVIII. Disentangling Galactic dust emission and cosmic infrared background anisotropies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aghanim, N.; Ashdown, M.; Aumont, J.

Using the Planck 2015 data release (PR2) temperature maps, we separate Galactic thermal dust emission from cosmic infrared background (CIB) anisotropies. For this purpose, we implement a specifically tailored component-separation method, the so-called generalized needlet internal linear combination (GNILC) method, which uses spatial information (the angular powerspectra) to disentangle the Galactic dust emission and CIB anisotropies. We produce significantly improved all-sky maps of Planck thermal dust emission, with reduced CIB contamination, at 353, 545, and 857 GHz. By reducing the CIB contamination of the thermal dust maps, we provide more accurate estimates of the local dust temperature and dust spectralmore » index over the sky with reduced dispersion, especially at high Galactic latitudes above b = ±20°. We find that the dust temperature is T = (19.4 ± 1.3) K and the dust spectral index is β = 1.6 ± 0.1 averaged over the whole sky, while T = (19.4 ± 1.5) K and β = 1.6 ± 0.2 on 21% of the sky at high latitudes. Moreover, subtracting the new CIB-removed thermal dust maps from the CMB-removed Planck maps gives access to the CIB anisotropies over 60% of the sky at Galactic latitudes |b| > 20°. Because they are a significant improvement over previous Planck products, the GNILC maps are recommended for thermal dust science. The new CIB maps can be regarded as indirect tracers of the dark matter and they are recommended for exploring cross-correlations with lensing and large-scale structure optical surveys. The reconstructed GNILC thermal dust and CIB maps are delivered as Planck products.« less

Promoting Diversity in STEM through Active Recruiting and Mentoring: The Pre-Major in Astronomy Program (Pre-MAP) at the University of Washington

NASA Astrophysics Data System (ADS)

Schwieterman, Edward; Binder, Breanna; Tremmel, Michael; Garofali, Kristen; Agol, Eric; Meadows, Victoria

2015-11-01

The Pre-Major in Astronomy Program (Pre-MAP) is a research and mentoring program for underclassmen and transfer students offered by the University of Washington Astronomy Department since 2005. The primary goal of Pre-MAP is to recruit and retain students from groups traditionally underrepresented in science, technology, engineering, and mathematics (STEM) through early exposure to research. The Pre-MAP seminar is the core component of the program and offers instruction in computing skills, data manipulation, science writing, statistical analysis, and scientific speaking and presentation skills. Students choose research projects proposed by faculty, post-docs and graduate students in areas related to astrophysics, planetary science, and astrobiology. Pre-MAP has been successful in retaining underrepresented students in STEM fields relative to the broader UW population, and we've found these students are more likely to graduate and excel academically than their peers. As of spring 2015, more than one hundred students have taken the Pre-MAP seminar, and both internal and external evaluations have shown that all groups of participating students report an increased interest in astronomy and science careers at the end of the seminar. Several former Pre-MAP students have obtained or are pursuing doctoral and master’s degrees in STEM fields; many more work at NASA centers, teaching colleges, or as engineers or data analysts. Pre- MAP student research has produced dozens of publications in peer-reviewed research journals. This talk will provide an overview of the program: the structure of the seminar, examples of projects completed by students, cohort-building activities outside the seminar, funding sources, recruitment strategies, and the aggregate demographic and achievement data of our students. It is our hope that similar programs may be adopted successfully at other institutions.

1831: the map that launched the idea of global health.

PubMed

Koch, Tom

2014-08-01

Today we take for granted the idea of global health, of disease as an international event. Increasingly, we assume as well that the international spread of disease can be traced to human travel patterns as well as to recurring environmental conditions. Perversely, the idea of ‘global health’ and its inverse, global disease, owes little to the three-dimensional imaging of the planet and almost everything to the two-dimensional plane of the map. Here the idea of global disease is traced from its beginnings in the 18th century to its 19th-century introduction in maps of the first cholera pandemic. This global perspective, and the responsibilities it promoted among civil officials, can be seen in modern studies of cancer, influenza and other conditions with both environmental foundations and international presence.

Reducing Future International Chemical and Biological Dangers.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Haddal, Chad; Bull, Diana L.; Hernandez, Patricia Marie

The International Biological and Chemical Threat Reduction Program at Sandia National Laboratories is developing a 15 - year technology road map in support the United States Government efforts to reduce international chemical and biological dangers . In 2017, the program leadership chartered an analysis team to explore dangers in the future international chemical and biological landscape through engagements with national security experts within and beyond Sandia to gain a multidisciplinary perspective on the future . This report offers a hi gh level landscape of future chemical and biological dangers based upon analysis of those engagements and provides support for furthermore » technology road map development.« less

Three-dimensional radar imaging of structures and craters in the Martian polar caps.

PubMed

Putzig, Nathaniel E; Smith, Isaac B; Perry, Matthew R; Foss, Frederick J; Campbell, Bruce A; Phillips, Roger J; Seu, Roberto

2018-07-01

Over the last decade, observations acquired by the Shallow Radar (SHARAD) sounder on individual passes of the Mars Reconnaissance Orbiter have revealed the internal structure of the Martian polar caps and provided new insights into the formation of the icy layers within and their relationship to climate. However, a complete picture of the cap interiors has been hampered by interfering reflections from off-nadir surface features and signal losses associated with sloping structures and scattering. Foss et al. (2017) addressed these limitations by assembling three-dimensional data volumes of SHARAD observations from thousands of orbital passes over each polar region and applying geometric corrections simultaneously. The radar volumes provide unprecedented views of subsurface features, readily imaging structures previously inferred from time-intensive manual analysis of single-orbit data (e.g., trough-bounding surfaces, a buried chasma, and a basal unit in the north, massive carbon-dioxide ice deposits and discontinuous layered sequences in the south). Our new mapping of the carbon-dioxide deposits yields a volume of 16,500 km 3 , 11% larger than the prior estimate. In addition, the radar volumes newly reveal other structures, including what appear to be buried impact craters with no surface expression. Our first assessment of 21 apparent craters at the base of the north polar layered deposits suggests a Hesperian age for the substrate, consistent with that of the surrounding plains as determined from statistics of surface cratering rates. Planned mapping of similar features throughout both polar volumes may provide new constraints on the age of the icy layered deposits. The radar volumes also provide new topographic data between the highest latitudes observed by the Mars Orbiter Laser Altimeter and those observed by SHARAD. In general, mapping of features in these radar volumes is placing new constraints on the nature and evolution of the polar deposits and associated climate changes.

Three-dimensional radar imaging of structures and craters in the Martian polar caps

NASA Astrophysics Data System (ADS)

Putzig, Nathaniel E.; Smith, Isaac B.; Perry, Matthew R.; Foss, Frederick J.; Campbell, Bruce A.; Phillips, Roger J.; Seu, Roberto

2018-07-01

Over the last decade, observations acquired by the Shallow Radar (SHARAD) sounder on individual passes of the Mars Reconnaissance Orbiter have revealed the internal structure of the Martian polar caps and provided new insights into the formation of the icy layers within and their relationship to climate. However, a complete picture of the cap interiors has been hampered by interfering reflections from off-nadir surface features and signal losses associated with sloping structures and scattering. Foss et al. (The Leading Edge 36, 43-57, 2017, https://doi.org/10.1190/tle36010043.1) addressed these limitations by assembling three-dimensional data volumes of SHARAD observations from thousands of orbital passes over each polar region and applying geometric corrections simultaneously. The radar volumes provide unprecedented views of subsurface features, readily imaging structures previously inferred from time-intensive manual analysis of single-orbit data (e.g., trough-bounding surfaces, a buried chasma, and a basal unit in the north, massive carbon-dioxide ice deposits and discontinuous layered sequences in the south). Our new mapping of the carbon-dioxide deposits yields a volume of 16,500 km3, 11% larger than the prior estimate. In addition, the radar volumes newly reveal other structures, including what appear to be buried impact craters with no surface expression. Our first assessment of 21 apparent craters at the base of the north polar layered deposits suggests a Hesperian age for the substrate, consistent with that of the surrounding plains as determined from statistics of surface cratering rates. Planned mapping of similar features throughout both polar volumes may provide new constraints on the age of the icy layered deposits. The radar volumes also provide new topographic data between the highest latitudes observed by the Mars Orbiter Laser Altimeter and those observed by SHARAD. In general, mapping of features in these radar volumes is placing new constraints on the nature and evolution of the polar deposits and associated climate changes.

Building Map Skills: The Other Energy Crisis.

ERIC Educational Resources Information Center

Branson, Margaret S.

1983-01-01

People in the developing world worry about the shrinkage of forests and the scarcity of firewood. An international team of geographers assessed desertification and prepared a map. Students can analyze a simplified map and answer questions that will help them understand desertification. (AM)

The 1973 dust storm on Mars: Maps from hourly photographs

NASA Technical Reports Server (NTRS)

Martin, L. J.

1975-01-01

The hourly progress of the 1973 major Martian storm was mapped using photographic images from the International Planetary Patrol. Two series of 20 daily maps show the semi-hourly positions of the storm brightenings in red light and blue light. The maps indicate that the 1973 storm had many similarities to the 1971 storm.

IFLA General Conference, 1986. Special Libraries Division. Section: Geography and Map Library. Papers.

ERIC Educational Resources Information Center

International Federation of Library Associations and Institutions, The Hague (Netherlands).

Four papers on geography and map libraries were presented at the 1986 International Federation of Library Associations (IFLA) conference. "Generation and Utilization of Maps and Atlases in Japan," by Takashi Morita of Japan, presents an overview of the making and uses of maps and atlases in Japan and concludes that a comprehensive…

Brain structural plasticity with spaceflight.

PubMed

Koppelmans, Vincent; Bloomberg, Jacob J; Mulavara, Ajitkumar P; Seidler, Rachael D

2016-01-01

Humans undergo extensive sensorimotor adaptation during spaceflight due to altered vestibular inputs and body unloading. No studies have yet evaluated the effects of spaceflight on human brain structure despite the fact that recently reported optic nerve structural changes are hypothesized to occur due to increased intracranial pressure occurring with microgravity. This is the first report on human brain structural changes with spaceflight. We evaluated retrospective longitudinal T2-weighted MRI scans and balance data from 27 astronauts (thirteen ~2-week shuttle crew members and fourteen ~6-month International Space Station crew members) to determine spaceflight effects on brain structure, and whether any pre to postflight brain changes are associated with balance changes. Data were obtained from the NASA Lifetime Surveillance of Astronaut Health. Brain scans were segmented into gray matter maps and normalized into MNI space using a stepwise approach through subject specific templates. Non-parametric permutation testing was used to analyze pre to postflight volumetric gray matter changes. We found extensive volumetric gray matter decreases, including large areas covering the temporal and frontal poles and around the orbits. This effect was larger in International Space Station versus shuttle crew members in some regions. There were bilateral focal gray matter increases within the medial primary somatosensory and motor cortex; i.e., the cerebral areas where the lower limbs are represented. These intriguing findings are observed in a retrospective data set; future prospective studies should probe the underlying mechanisms and behavioral consequences.

X-ray Crystallography Facility

NASA Technical Reports Server (NTRS)

1999-01-01

University of Alabama engineer Lance Weiss briefs NASA astronaut Dr. Bornie Dunbar about the design and capabilities of the X-ray Crystallography Facility under development at the Center for Macromolecular Crystallography of the University of Alabama at Birmingham, AL, April 21, 1999. The X-ray Crystallography Facility is designed to speed the collection of protein structure information from crystals grown aboard the International Space Station. By measuring and mapping the protein crystal structure in space, researchers will avoid exposing the delicate crystals to the rigors of space travel and make important research data available to scientists much faster. The X-ray Crystallography facility is being designed and developed by the Center for Macromolecular Crystallography of the University of Alabama at Birmingham, a NASA Commercial Space Center.

X-ray Crystallography Facility

NASA Technical Reports Server (NTRS)

1999-01-01

University of Alabama engineer Stacey Giles briefs NASA astronaut Dr. Bornie Dunbar about the design and capabilities of the X-ray Crystallography Facility under development at the Center for Macromolecular Crystallography of the University of Alabama at Birmingham, AL, April 21, 1999. The X-ray Crystallography Facility is designed to speed the collection of protein structure information from crystals grown aboard the International Space Station. By measuring and mapping the protein crystal structure in space, researchers will avoid exposing the delicate crystals to the rigors of space travel and make important research data available to scientists much faster. The X-ray Crystallography facility is being designed and developed by the Center for Macromolecular Crystallography of the University of Alabama at Birmingham, a NASA Commercial Space Center.

Genetic Mapping

MedlinePlus

... Sheets A Brief Guide to Genomics About NHGRI Research About the International HapMap Project Biological Pathways Chromosome Abnormalities Chromosomes Cloning Comparative Genomics DNA Microarray Technology DNA Sequencing Deoxyribonucleic Acid ( ...

Averaged kick maps: less noise, more signal…and probably less bias

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pražnikar, Jure; Afonine, Pavel V.; Gunčar, Gregor

2009-09-01

Averaged kick maps are the sum of a series of individual kick maps, where each map is calculated from atomic coordinates modified by random shifts. These maps offer the possibility of an improved and less model-biased map interpretation. Use of reliable density maps is crucial for rapid and successful crystal structure determination. Here, the averaged kick (AK) map approach is investigated, its application is generalized and it is compared with other map-calculation methods. AK maps are the sum of a series of kick maps, where each kick map is calculated from atomic coordinates modified by random shifts. As such, theymore » are a numerical analogue of maximum-likelihood maps. AK maps can be unweighted or maximum-likelihood (σ{sub A}) weighted. Analysis shows that they are comparable and correspond better to the final model than σ{sub A} and simulated-annealing maps. The AK maps were challenged by a difficult structure-validation case, in which they were able to clarify the problematic region in the density without the need for model rebuilding. The conclusion is that AK maps can be useful throughout the entire progress of crystal structure determination, offering the possibility of improved map interpretation.« less

Global Mapping Project - Applications and Development of Version 2 Dataset

NASA Astrophysics Data System (ADS)

Ubukawa, T.; Nakamura, T.; Otsuka, T.; Iimura, T.; Kishimoto, N.; Nakaminami, K.; Motojima, Y.; Suga, M.; Yatabe, Y.; Koarai, M.; Okatani, T.

2012-07-01

The Global Mapping Project aims to develop basic geospatial information of the whole land area of the globe, named Global Map, through the cooperation of National Mapping Organizations (NMOs) around the world. The Global Map data can be a base of global geospatial infrastructure and is composed of eight layers: Boundaries, Drainage, Transportation, Population Centers, Elevation, Land Use, Land Cover and Vegetation. The Global Map Version 1 was released in 2008, and the Version 2 will be released in 2013 as the data are to be updated every five years. In 2009, the International Steering Committee for Global Mapping (ISCGM) adopted new Specifications to develop the Global Map Version 2 with a change of its format so that it is compatible with the international standards, namely ISO 19136 and ISO 19115. With the support of the secretariat of ISCGM, the project participating countries are accelerating their data development toward the completion of the global coverage in 2013, while some countries have already released their Global Map version 2 datasets since 2010. Global Map data are available from the Internet free of charge for non-commercial purposes, which can be used to predict, assess, prepare for and cope with global issues by combining with other spatial data. There are a lot of Global Map applications in various fields, and further utilization of Global Map is expected. This paper summarises the activities toward the development of the Global Map Version 2 as well as some examples of the Global Map applications in various fields.

Potential Energy Surface-Based Automatic Deduction of Conformational Transition Networks and Its Application on Quantum Mechanical Landscapes of d-Glucose Conformers.

PubMed

Satoh, Hiroko; Oda, Tomohiro; Nakakoji, Kumiyo; Uno, Takeaki; Tanaka, Hiroaki; Iwata, Satoru; Ohno, Koichi

2016-11-08

This paper describes our approach that is built upon the potential energy surface (PES)-based conformational analysis. This approach automatically deduces a conformational transition network, called a conformational reaction route map (r-map), by using the Scaled Hypersphere Search of the Anharmonic Downward Distortion Following method (SHS-ADDF). The PES-based conformational search has been achieved by using large ADDF, which makes it possible to trace only low transition state (TS) barriers while restraining bond lengths and structures with high free energy. It automatically performs sampling the minima and TS structures by simply taking into account the mathematical feature of PES without requiring any a priori specification of variable internal coordinates. An obtained r-map is composed of equilibrium (EQ) conformers connected by reaction routes via TS conformers, where all of the reaction routes are already confirmed during the process of the deduction using the intrinsic reaction coordinate (IRC) method. The postcalculation analysis of the deduced r-map is interactively carried out using the RMapViewer software we have developed. This paper presents computational details of the PES-based conformational analysis and its application to d-glucose. The calculations have been performed for an isolated glucose molecule in the gas phase at the RHF/6-31G level. The obtained conformational r-map for α-d-glucose is composed of 201 EQ and 435 TS conformers and that for β-d-glucose is composed of 202 EQ and 371 TS conformers. For the postcalculation analysis of the conformational r-maps by using the RMapViewer software program we have found multiple minimum energy paths (MEPs) between global minima of 1 C 4 and 4 C 1 chair conformations. The analysis using RMapViewer allows us to confirm the thermodynamic and kinetic predominance of 4 C 1 conformations; that is, the potential energy of the global minimum of 4 C 1 is lower than that of 1 C 4 (thermodynamic predominance) and that the highest energy of those of all the TS structures along a route from 4 C 1 to 1 C 4 is lower than that of 1 C 4 to 4 C 1 (kinetic predominance).

Neuroarchitecture and neuroanatomy of the Drosophila central complex: A GAL4-based dissection of protocerebral bridge neurons and circuits.

PubMed

Wolff, Tanya; Iyer, Nirmala A; Rubin, Gerald M

2015-05-01

Insects exhibit an elaborate repertoire of behaviors in response to environmental stimuli. The central complex plays a key role in combining various modalities of sensory information with an insect's internal state and past experience to select appropriate responses. Progress has been made in understanding the broad spectrum of outputs from the central complex neuropils and circuits involved in numerous behaviors. Many resident neurons have also been identified. However, the specific roles of these intricate structures and the functional connections between them remain largely obscure. Significant gains rely on obtaining a comprehensive catalog of the neurons and associated GAL4 lines that arborize within these brain regions, and on mapping neuronal pathways connecting these structures. To this end, small populations of neurons in the Drosophila melanogaster central complex were stochastically labeled using the multicolor flip-out technique and a catalog was created of the neurons, their morphologies, trajectories, relative arrangements, and corresponding GAL4 lines. This report focuses on one structure of the central complex, the protocerebral bridge, and identifies just 17 morphologically distinct cell types that arborize in this structure. This work also provides new insights into the anatomical structure of the four components of the central complex and its accessory neuropils. Most strikingly, we found that the protocerebral bridge contains 18 glomeruli, not 16, as previously believed. Revised wiring diagrams that take into account this updated architectural design are presented. This updated map of the Drosophila central complex will facilitate a deeper behavioral and physiological dissection of this sophisticated set of structures. © 2014 Wiley Periodicals, Inc.

Incorporating Mind Maps into Teaching and Learning in Higher Education: My Experience as an International University Lecturer

ERIC Educational Resources Information Center

Guo, Xin

2014-01-01

This article seeks to share the author's teaching experience as an international lecturer in a UK university and in particular promote the use of Mind Maps (MM) in teaching and learning in higher education. The audience to whom the article could be beneficial is university lecturers who either are in their early teaching career or face challenges…

Mapping adaptation opportunities and activities in an interactive atlas.

PubMed

Morris, Daniel F; Krishnan, Nisha

2012-01-01

The need for transparency is taking more prominence in international climate negotiations as developed countries pledge large sums of money to foster adaptation efforts in developing countries. Tools that provide accurate and up-to-date spatial information that can be easily used and vetted by local practitioners may provide effective and affordable ways to improve transparency. The Global Adaptation Atlas is such a tool, combining vetted, publicly available climate impact data with timely maps of on the ground adaptation projects to highlight confluences of effects of climate change with actions taken to address those effects. Here, we describe the structure and general functions of the Global Adaptation Atlas and explain how it may be utilized to track short-term investments in adaptation. Over longer time scales, it may also help gauge the effectiveness of specific adaptation investments as well as reveal how different climate impacts affect long-term investment in differing regions.

KSC-2011-6804

NASA Image and Video Library

2011-09-08

CAPE CANAVERAL, Fla. -- NASA's Gravity Recovery and Interior Laboratory mission is readied for liftoff aboard a United Launch Alliance Delta II Heavy rocket from Space Launch Complex 17B on Cape Canaveral Air Force Station. GRAIL will fly twin spacecraft in tandem around the moon to precisely measure and map variations in the moon's gravitational field. The mission will provide the most accurate global gravity field to date for any planet, including Earth. This detailed information will reveal differences in the density of the moon's crust and mantle and will help answer fundamental questions about the moon's internal structure, thermal evolution, and history of collisions with asteroids. The aim is to map the moon's gravity field so completely that future lunar vehicles can safely navigate anywhere on the moon’s surface. Launch is scheduled for 8:37:06 a.m. EDT Sept. 8. For more information, visit http://www.nasa.gov/grail. Photo credit: NASA

KSC-2011-6871

NASA Image and Video Library

2011-09-10

CAPE CANAVERAL, Fla. – The United Launch Alliance Delta II Heavy rocket lifted off at 9:08 a.m. EDT Sept. 10 from Space Launch Complex 17B on Cape Canaveral Air Force Station in Florida carrying NASA’s twin Gravity Recovery and Interior Laboratory (GRAIL) mission to the moon. GRAIL will fly twin spacecraft in tandem around the moon to precisely measure and map variations in the moon's gravitational field. The mission will provide the most accurate global gravity field to date for any planet, including Earth. This detailed information will reveal differences in the density of the moon's crust and mantle and will help answer fundamental questions about the moon's internal structure, thermal evolution, and history of collisions with asteroids. The aim is to map the moon's gravity field so completely that future moon vehicles can safely navigate anywhere on the moon’s surface. For more information, visit http://www.nasa.gov/grail. Photo credit: NASA/Kim Shiflett

KSC-2011-6869

NASA Image and Video Library

2011-09-10

CAPE CANAVERAL, Fla. – Surrounded by an early morning sky, the United Launch Alliance Delta II Heavy rocket sits on Space Launch Complex 17B on Cape Canaveral Air Force Station in Florida as it waits to launch NASA’s twin Gravity Recovery and Interior Laboratory (GRAIL) mission to the moon. GRAIL will fly twin spacecraft in tandem around the moon to precisely measure and map variations in the moon's gravitational field. The mission will provide the most accurate global gravity field to date for any planet, including Earth. This detailed information will reveal differences in the density of the moon's crust and mantle and will help answer fundamental questions about the moon's internal structure, thermal evolution, and history of collisions with asteroids. The aim is to map the moon's gravity field so completely that future moon vehicles can safely navigate anywhere on the moon’s surface. For more information, visit http://www.nasa.gov/grail. Photo credit: NASA/Kim Shiflett

KSC-2011-6807

NASA Image and Video Library

2011-09-08

CAPE CANAVERAL, Fla. -- Media representatives prepare to photograph the launch of NASA's Gravity Recovery and Interior Laboratory mission at Press Site 1 near Space Launch Complex 17B on Cape Canaveral Air Force Station. Liftoff aboard a United Launch Alliance Delta II Heavy rocket is scheduled for 8:37:06 a.m. EDT. GRAIL will fly twin spacecraft in tandem around the moon to precisely measure and map variations in the moon's gravitational field. The mission will provide the most accurate global gravity field to date for any planet, including Earth. This detailed information will reveal differences in the density of the moon's crust and mantle and will help answer fundamental questions about the moon's internal structure, thermal evolution, and history of collisions with asteroids. The aim is to map the moon's gravity field so completely that future lunar vehicles can safely navigate anywhere on the moon’s surface. For more information, visit http://www.nasa.gov/grail. Photo credit: NASA/Ken Thornsley

KSC-2011-6812

NASA Image and Video Library

2011-09-08

CAPE CANAVERAL, Fla. -- The countdown to launch of the United Launch Alliance Delta II Heavy rocket for NASA's Gravity Recovery and Interior Laboratory mission nears T-0 at Space Launch Complex 17B on Cape Canaveral Air Force Station. Liftoff is scheduled for 8:37:06 a.m. EDT. GRAIL will fly twin spacecraft in tandem around the moon to precisely measure and map variations in the moon's gravitational field. The mission will provide the most accurate global gravity field to date for any planet, including Earth. This detailed information will reveal differences in the density of the moon's crust and mantle and will help answer fundamental questions about the moon's internal structure, thermal evolution, and history of collisions with asteroids. The aim is to map the moon's gravity field so completely that future lunar vehicles can safely navigate anywhere on the moon’s surface. For more information, visit http://www.nasa.gov/grail. Photo credit: NASA/Ken Thornsley

KSC-2011-6802

NASA Image and Video Library

2011-09-08

CAPE CANAVERAL, Fla. -- Launch preparations are under way as dawn breaks at Space Launch Complex 17B on Cape Canaveral Air Force Station for NASA's Gravity Recovery and Interior Laboratory mission aboard a United Launch Alliance Delta II Heavy rocket. GRAIL will fly twin spacecraft in tandem around the moon to precisely measure and map variations in the moon's gravitational field. The mission will provide the most accurate global gravity field to date for any planet, including Earth. This detailed information will reveal differences in the density of the moon's crust and mantle and will help answer fundamental questions about the moon's internal structure, thermal evolution, and history of collisions with asteroids. The aim is to map the moon's gravity field so completely that future lunar vehicles can safely navigate anywhere on the moon’s surface. Launch is scheduled for 8:37:06 a.m. EDT Sept. 8. For more information, visit http://www.nasa.gov/grail. Photo credit: NASA

KSC-2011-6867

NASA Image and Video Library

2011-09-10

CAPE CANAVERAL, Fla. – Surrounded by an early morning sky, the United Launch Alliance Delta II Heavy rocket sits on Space Launch Complex 17B on Cape Canaveral Air Force Station in Florida as it waits to launch NASA’s twin Gravity Recovery and Interior Laboratory (GRAIL) mission to the moon. GRAIL will fly twin spacecraft in tandem around the moon to precisely measure and map variations in the moon's gravitational field. The mission will provide the most accurate global gravity field to date for any planet, including Earth. This detailed information will reveal differences in the density of the moon's crust and mantle and will help answer fundamental questions about the moon's internal structure, thermal evolution, and history of collisions with asteroids. The aim is to map the moon's gravity field so completely that future moon vehicles can safely navigate anywhere on the moon’s surface. For more information, visit http://www.nasa.gov/grail. Photo credit: NASA/Kim Shiflett

KSC-2011-6868

NASA Image and Video Library

2011-09-10

CAPE CANAVERAL, Fla. – Bathed in light against an early morning sky, the United Launch Alliance Delta II Heavy rocket sits on Space Launch Complex 17B on Cape Canaveral Air Force Station in Florida as it waits to launch NASA’s twin Gravity Recovery and Interior Laboratory (GRAIL) mission to the moon. GRAIL will fly twin spacecraft in tandem around the moon to precisely measure and map variations in the moon's gravitational field. The mission will provide the most accurate global gravity field to date for any planet, including Earth. This detailed information will reveal differences in the density of the moon's crust and mantle and will help answer fundamental questions about the moon's internal structure, thermal evolution, and history of collisions with asteroids. The aim is to map the moon's gravity field so completely that future moon vehicles can safely navigate anywhere on the moon’s surface. For more information, visit http://www.nasa.gov/grail. Photo credit: NASA/Kim Shiflett

KSC-2011-6870

NASA Image and Video Library

2011-09-10

CAPE CANAVERAL, Fla. – A U.S. Air Force helicopter flies overhead as the United Launch Alliance Delta II Heavy rocket sits on Space Launch Complex 17B on Cape Canaveral Air Force Station in Florida waiting to launch NASA’s twin Gravity Recovery and Interior Laboratory (GRAIL) mission to the moon. GRAIL will fly twin spacecraft in tandem around the moon to precisely measure and map variations in the moon's gravitational field. The mission will provide the most accurate global gravity field to date for any planet, including Earth. This detailed information will reveal differences in the density of the moon's crust and mantle and will help answer fundamental questions about the moon's internal structure, thermal evolution, and history of collisions with asteroids. The aim is to map the moon's gravity field so completely that future moon vehicles can safely navigate anywhere on the moon’s surface. For more information, visit http://www.nasa.gov/grail. Photo credit: NASA/Kim Shiflett

KSC-2011-6805

NASA Image and Video Library

2011-09-08

CAPE CANAVERAL, Fla. -- The countdown to launch of the United Launch Alliance Delta II Heavy rocket for NASA's Gravity Recovery and Interior Laboratory mission is winding down at Space Launch Complex 17B on Cape Canaveral Air Force Station. Liftoff is scheduled for 8:37:06 a.m. EDT. GRAIL will fly twin spacecraft in tandem around the moon to precisely measure and map variations in the moon's gravitational field. The mission will provide the most accurate global gravity field to date for any planet, including Earth. This detailed information will reveal differences in the density of the moon's crust and mantle and will help answer fundamental questions about the moon's internal structure, thermal evolution, and history of collisions with asteroids. The aim is to map the moon's gravity field so completely that future lunar vehicles can safely navigate anywhere on the moon’s surface. For more information, visit http://www.nasa.gov/grail. Photo credit: NASA/Ken Thornsley

Developing Land Surface Type Map with Biome Classification Scheme Using Suomi NPP/JPSS VIIRS Data

NASA Astrophysics Data System (ADS)

Zhang, Rui; Huang, Chengquan; Zhan, Xiwu; Jin, Huiran

2016-08-01

Accurate representation of actual terrestrial surface types at regional to global scales is an important element for a wide range of applications, such as land surface parameterization, modeling of biogeochemical cycles, and carbon cycle studies. In this study, in order to meet the requirement of the retrieval of global leaf area index (LAI) and fraction of photosynthetically active radiation absorbed by the vegetation (fPAR) and other studies, a global map generated from Suomi National Polar- orbiting Partnership (S-NPP) Visible Infrared Imaging Radiometer Suite (VIIRS) surface reflectance data in six major biome classes based on their canopy structures, which include: Grass/Cereal Crops, Shrubs, Broadleaf Crops, Savannas, Broadleaf Forests, and Needleleaf Forests, was created. The primary biome classes were converted from an International Geosphere-Biosphere Program (IGBP) legend global surface type data that was created in previous study, and the separation of two crop types are based on a secondary classification.

A financial market model with two discontinuities: Bifurcation structures in the chaotic domain

NASA Astrophysics Data System (ADS)

Panchuk, Anastasiia; Sushko, Iryna; Westerhoff, Frank

2018-05-01

We continue the investigation of a one-dimensional piecewise linear map with two discontinuity points. Such a map may arise from a simple asset-pricing model with heterogeneous speculators, which can help us to explain the intricate bull and bear behavior of financial markets. Our focus is on bifurcation structures observed in the chaotic domain of the map's parameter space, which is associated with robust multiband chaotic attractors. Such structures, related to the map with two discontinuities, have been not studied before. We show that besides the standard bandcount adding and bandcount incrementing bifurcation structures, associated with two partitions, there exist peculiar bandcount adding and bandcount incrementing structures involving all three partitions. Moreover, the map's three partitions may generate intriguing bistability phenomena.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Willard, H.F.; Cremers, F.; Mandel, J.L.

A high-quality integrated genetic and physical map of the X chromosome from telomere to telomere, based primarily on YACs formatted with probes and STSs, is increasingly close to reality. At the Fifth International X Chromosome Workshop, organized by A.M. Poustka and D. Schlessinger in Heidelberg, Germany, April 24--27, 1994, substantial progress was recorded on extension and refinement of the physical map, on the integration of genetic and cytogenetic data, on attempts to use the map to direct gene searches, and on nascent large-scale sequencing efforts. This report summarizes physical and genetic mapping information presented at the workshop and/or published sincemore » the reports of the fourth International X Chromosome Workshop. The principle aim of the workshop was to derive a consensus map of the chromosome, in terms of physical contigs emphasizing the location of genes and microsatellite markers. The resulting map is presented and updates previous versions. This report also updates the list of highly informative microsatellites. The text highlights the working state of the map, the genes known to reside on the X, and the progress toward integration of various types of data.« less

A structured policy review of the principles of professional self-regulation.

PubMed

Benton, D C; González-Jurado, M A; Beneit-Montesinos, J V

2013-03-01

The International Council of Nurses (ICN) has, for many years, based its work on professional self-regulation on a set of 12 principles. These principles are research based and were identified nearly three decades ago. ICN has conducted a number of reviews of the principles; however, changes have been minimal. In the past 5-10 years, a number of authors and governments, often as part of the review of regulatory systems, have started to propose principles to guide the way regulatory frameworks are designed and implemented. These principles vary in number and content. This study examines the current policy literature on principle-based regulation and compares this with the set of principles advocated by the ICN. A systematic search of the literature on principle-based regulation is used as the basis for a qualitative thematic analysis to compare and contrast the 12 principles of self-regulation with more recently published work. A mapping of terms based on a detailed description of the principles used in the various research and policy documents was generated. This mapping forms the basis of a critique of the current ICN principles. A professional self-regulation advocated by the ICN were identified. A revised and extended set of 13 principles is needed if contemporary developments in the field of regulatory frameworks are to be accommodated. These revised principles should be considered for adoption by the ICN to underpin their advocacy work on professional self-regulation. © 2013 The Authors. International Nursing Review © 2013 International Council of Nurses.

Longitudinal analysis on human cervical tissue using optical coherence tomography (Conference Presentation)

NASA Astrophysics Data System (ADS)

Gan, Yu; Yao, Wang; Myers, Kristin M.; Vink, Joy-Sarah Y.; Wapner, Ronald J.; Hendon, Christine P.

2017-02-01

Uterine cervical collagen fiber network is vital to the normal cervical function in pregnancy. Previously, we presented an orientation estimation method to enable dispersion analysis on a single axial slice of human cervical tissue obtained from the upper half of cervix using optical coherence tomography (OCT). How the collagen fiber network structure changes from the internal os (top of the cervix which meets the uterus) to external os (bottom of cervix which extends into the vagina), remains unknown due to depth penetration limitations of OCT. To establish a collagen fiber directionality "map" of the entire cervix, we imaged serial axial slices of human NP (n=11) and PG (n=2) cervical tissue obtained from the internal to external os using Institutional Review Board approved protocols at Columbia University Medical Center. Each slice was divided into four quadrants. In each quadrant, we stitched multiple overlapped OCT volumes and analyzed the en face images that were parallel to the surface. A pixel-wise directionality map was generated. We analyzed fiber trend by measuring the mean angles and quantified dispersion by calculating the standard deviation of the fiber direction over a region of 400 μm × 400 μm. For the initial four samples, our analysis confirms a circumferential fiber pattern in the outer region of slices at all depths. We found that the standard deviation close to internal os showed no significance to the standard deviation close to external os (p>0.05), indicating comparable dispersion.

The role of discrete intrabasement shear zones during multiphase continental rifting

NASA Astrophysics Data System (ADS)

Phillips, Thomas B.; Jackson, Christopher A.-L.; Bell, Rebecca E.; Duffy, Oliver B.; Fossen, Haakon

2016-04-01

Rift systems form within areas of relatively weak, heterogeneous lithosphere, containing a range of pre-existing structures imparted from previous tectonic events. The extent to which these structures may reactivate during later rift phases, and therefore affect the geometry and evolution of superposed rift systems, is poorly understood. The greatest obstacle to understanding how intrabasement structures influence the overlying rift is obtaining detailed constraints on the origin and 3D geometry of structures within crystalline basement. Such structures are often deeply buried beneath rift systems and therefore rarely sampled directly. In addition, due to relatively low internal acoustic impedance contrasts and large burial depths, crystalline basement typically appears acoustically transparent on seismic reflection data showing no resolvable internal structure. However, offshore SW Norway, beneath the Egersund Basin, intrabasement structures are exceptionally well-imaged due to large impedance contrasts within a highly heterogeneous and shallow basement. We use borehole-constrained 2D and 3D seismic reflection data to constrain the 3D geometry of these intrabasement reflections, and examine their interactions with the overlying rift system. Two types of intrabasement structure are observed: (i) thin (c. 100 m) reflections displaying a characteristic trough-peak-trough wavetrain; and (ii) thick (c. 1 km), sub-parallel reflection packages dipping at c. 30°. Through 1D waveform modelling we show that these reflection patterns arise from a layered sequence as opposed to a single interface. Integrating this with our seismic mapping we correlate these structures to the established onshore geology; specifically layered mylonites associated with the Caledonian thrust belt and cross-cutting extensional Devonian shear zones. We observe multiple phases of reactivation along these structures throughout multiple rift events, in addition to a range of interactions with overlying rift-related faults: (i) Faults exploit planes of weakness internally within the shear zones; (ii) faults initiate within the hangingwall and subsequently merge along the intrabasement structure at depth; and (iii) faults initiate independently from and cross-cut intrabasement structure. We find that reactivation preferentially occurs along the thicker, steeper intrabasement structures, the Devonian Shear Zones, with individual faults exploiting internal mylonite layers. Using a detailed 3D interpretation of intrabasement structures, correlated with the onshore geology, we show that large-scale Devonian shear zones act as a long-lived structural template for fault initiation throughout multiple rift phases. Rift-related faults inherit the orientation and location of underlying intrabasement structures.

Enhancing the usability and performance of structured association mapping algorithms using automation, parallelization, and visualization in the GenAMap software system

PubMed Central

2012-01-01

Background Structured association mapping is proving to be a powerful strategy to find genetic polymorphisms associated with disease. However, these algorithms are often distributed as command line implementations that require expertise and effort to customize and put into practice. Because of the difficulty required to use these cutting-edge techniques, geneticists often revert to simpler, less powerful methods. Results To make structured association mapping more accessible to geneticists, we have developed an automatic processing system called Auto-SAM. Auto-SAM enables geneticists to run structured association mapping algorithms automatically, using parallelization. Auto-SAM includes algorithms to discover gene-networks and find population structure. Auto-SAM can also run popular association mapping algorithms, in addition to five structured association mapping algorithms. Conclusions Auto-SAM is available through GenAMap, a front-end desktop visualization tool. GenAMap and Auto-SAM are implemented in JAVA; binaries for GenAMap can be downloaded from http://sailing.cs.cmu.edu/genamap. PMID:22471660

Method for removing atomic-model bias in macromolecular crystallography

DOEpatents

Terwilliger, Thomas C [Santa Fe, NM

2006-08-01

Structure factor bias in an electron density map for an unknown crystallographic structure is minimized by using information in a first electron density map to elicit expected structure factor information. Observed structure factor amplitudes are combined with a starting set of crystallographic phases to form a first set of structure factors. A first electron density map is then derived and features of the first electron density map are identified to obtain expected distributions of electron density. Crystallographic phase probability distributions are established for possible crystallographic phases of reflection k, and the process is repeated as k is indexed through all of the plurality of reflections. An updated electron density map is derived from the crystallographic phase probability distributions for each one of the reflections. The entire process is then iterated to obtain a final set of crystallographic phases with minimum bias from known electron density maps.

Selected satellite data on snow and ice in the Great Lakes basin 1972-73 /IFYGL/. [International Field Year for Great Lakes

NASA Technical Reports Server (NTRS)

Wiesnet, D. R.; Mcginnis, D. F.; Forsyth, D. G.

1974-01-01

Three snow-extent maps of the Lake Ontario drainage basin were prepared from NOAA-2 satellite visible band images during the International Field Year for the Great Lakes. These maps are discussed and the satellite data are evaluated for snow-extent mapping. The value of ERTS-1 imagery and digital data is also discussed in relation to the Lake Ontario basin studies. ERTS-1 MSS data are excellent for ice identification and analysis but are not useful for forecasting where timely receipt of data is imperative. NOAA-2 VHRR data are timely but the lower resolution of the VHRR makes identification of certain ice features difficult. NOAA-2 VHRR is well suited for snow-extent maps and thermal maps of large areas such as the 19,000 sq-km Lake Ontario basin.

Map and database of Quaternary faults and folds in Colombia and its offshore regions

USGS Publications Warehouse

Paris, Gabriel; Machette, Michael N.; Dart, Richard L.; Haller, Kathleen M.

2000-01-01

As part of the International Lithosphere Program’s “World Map of Major Active Faults,” the U.S. Geological Survey (USGS) is assisting in the compilation of a series of digital maps of Quaternary faults and folds in Western Hemisphere countries. The maps show the locations, ages, and activity rates of major earthquake-related features such as faults and fault-related folds. They are accompanied by databases that describe these features and document current information on their activity in the Quaternary. Top date, the project has published fault and fold maps for Costa Rica (Montero and others, 1998), Panama (Cowan and others, 1998), Venezuela (Audemard and others, 2000), Bolovia/Chile (Lavenu, and others, 2000), and Argentina (Costa and others, 2000). The project is a key part of the Global Seismic Hazards Assessment Program (ILP Project II-0) for the International Decade for Natural Hazard Disaster Reduction.

MC EMiNEM Maps the Interaction Landscape of the Mediator

PubMed Central

Niederberger, Theresa; Etzold, Stefanie; Lidschreiber, Michael; Maier, Kerstin C.; Martin, Dietmar E.; Fröhlich, Holger; Cramer, Patrick; Tresch, Achim

2012-01-01

The Mediator is a highly conserved, large multiprotein complex that is involved essentially in the regulation of eukaryotic mRNA transcription. It acts as a general transcription factor by integrating regulatory signals from gene-specific activators or repressors to the RNA Polymerase II. The internal network of interactions between Mediator subunits that conveys these signals is largely unknown. Here, we introduce MC EMiNEM, a novel method for the retrieval of functional dependencies between proteins that have pleiotropic effects on mRNA transcription. MC EMiNEM is based on Nested Effects Models (NEMs), a class of probabilistic graphical models that extends the idea of hierarchical clustering. It combines mode-hopping Monte Carlo (MC) sampling with an Expectation-Maximization (EM) algorithm for NEMs to increase sensitivity compared to existing methods. A meta-analysis of four Mediator perturbation studies in Saccharomyces cerevisiae, three of which are unpublished, provides new insight into the Mediator signaling network. In addition to the known modular organization of the Mediator subunits, MC EMiNEM reveals a hierarchical ordering of its internal information flow, which is putatively transmitted through structural changes within the complex. We identify the N-terminus of Med7 as a peripheral entity, entailing only local structural changes upon perturbation, while the C-terminus of Med7 and Med19 appear to play a central role. MC EMiNEM associates Mediator subunits to most directly affected genes, which, in conjunction with gene set enrichment analysis, allows us to construct an interaction map of Mediator subunits and transcription factors. PMID:22737066

Mid-Tertiary Isopach and Lithofacies Maps for the Los Angeles Region, California: Templates for Palinspastic Reconstruction to 17.4 Ma

USGS Publications Warehouse

McCulloh, Thane H.; Beyer, Larry A.

2004-01-01

Opening of the Neogene Los Angeles Basin began abruptly about 17.4 Ma. Extensional rifting, with local basaltic volcanism, began the process and accompanied its early stages. Crustal detachment, followed by clockwise tectonic rotation and translation of large crustal blocks has been shown by previous paleomagnetic declination measurements in the western Transverse Ranges Province northwest of the basin and by large strike-slip and dip-slip separations on several major faults transecting it. Successful palinspastic reconstruction of the region to its arrangement before 17.4 Ma depends on understanding and integration of many stratigraphic and structural components. Before 17.4 Ma, fluviatile, alluvial and floodplain deposits, interstratified in the younger part with shallow marine to deeper shelf transgressive equivalents, accumulated to thicknesses as great as several kilometers. This report maps the surface and subsurface extents, thickness variations, and facies patterns of these strata, the Sespe plus Vaqueros and Trancas Formations or equivalents. Separate southeast and northwest sectors are revealed, each with distinctive internal thickness and facies patterns, which must have been related before rifting and transrotation. Terrestrial vertebrate and marine molluscan and foraminiferal fossils, plus magnetostratigraphic profiles of other workers and a few dates of igneous rocks, provide timing for key depositional and structural events. Our preliminary reconstruction of the region brings the internal patterns of the northwest and southeast sectors toward congruity but leaves unsatisfied discrepancies that suggest important information is missing. The reconstruction focuses attention on critical elements, specific uncertainties, and deficiencies of prior reconstructions. It also provides a new foundation for further work

PREFACE: 3rd International Workshop on Materials Analysis and Processing in Magnetic Fields (MAP3)

NASA Astrophysics Data System (ADS)

Sakka, Yoshio; Hirota, Noriyuki; Horii, Shigeru; Ando, Tsutomu

2009-07-01

The 3rd International Workshop on Materials Analysis and Processing in Materials Fields (MAP3) was held on 14-16 May 2008 at the University of Tokyo, Japan. The first was held in March 2004 at the National High Magnetic Field Laboratory in Tallahassee, USA. Two years later the second took place in Grenoble, France. MAP3 was held at The University of Tokyo International Symposium, and jointly with MANA Workshop on Materials Processing by External Stimulation, and JSPS CORE Program of Construction of the World Center on Electromagnetic Processing of Materials. At the end of MAP3 it was decided that the next MAP4 will be held in Atlanta, USA in 2010. Processing in magnetic fields is a rapidly expanding research area with a wide range of promising applications in materials science. MAP3 focused on the magnetic field interactions involved in the study and processing of materials in all disciplines ranging from physics to chemistry and biology: Magnetic field effects on chemical, physical, and biological phenomena Magnetic field effects on electrochemical phenomena Magnetic field effects on thermodynamic phenomena Magnetic field effects on hydrodynamic phenomena Magnetic field effects on crystal growth Magnetic processing of materials Diamagnetic levitation Magneto-Archimedes effect Spin chemistry Application of magnetic fields to analytical chemistry Magnetic orientation Control of structure by magnetic fields Magnetic separation and purification Magnetic field-induced phase transitions Materials properties in high magnetic fields Development of NMR and MRI Medical application of magnetic fields Novel magnetic phenomena Physical property measurement by Magnetic fields High magnetic field generation> MAP3 consisted of 84 presentations including 16 invited talks. This volume of Journal of Physics: Conference Series contains the proceeding of MAP3 with 34 papers that provide a scientific record of the topics covered by the conference with the special topics (13 papers) in the journal Science and Technology of Advanced Materials. All articles have been refereed by experts in the field. Both of these journals are fully accessible electronically and can be cited and referenced in the usual way. It is our hope that the reader will enjoy and profit from the MAP3 Proceedings. Hitoshi Wada (Kashiwa, Japan) Chair Eric Beaugon (Grenoble, France) Hans J Schneider-Muntau (Tallahassee, USA) Co-chair Advisory Board Shigeo Asai (Nagoya, Japan) Koichi Kitazawa (Tokyo, Japan) Mitsuhiro Motokawa (Sendai, Japan) Shoogo Ueno (Fukuoka, Japan) Robert Tournier (Grenoble, France) Justin Schwartz (Tallahassee, USA) J C Maan (Nijmegen, Netherland) Scientific Committee Yoshifumi Tanimoto (Hiroshima, Japan) Masuhiro Yamaguchi (Yokohama, Japan) Tsunehisa Kimura (Kyoto, Japan) Yoshio Sakka (Tsukuba Japan) Ryoichi Aogaki (Tokyo, Japan) Jyunji Miyakoshi (Hirosaki, Japan) Kazuo Watanabe (Sendai, Japan) James M Valles Jr. (Providence, USA) Joon Pyo Park (Pohang, Korea) Qiang Wang (Shenyang, China) Nicole Pamme (Hull, UK) Sophie Rivoirard (Grenoble, France) P C M Christianen (Nijmegen, Netherland) Local Organizing Committee Isao Yamamoto Masafumi Yamato Shigeru Horii Norihito Sogoshi Masateru Ikehata Noriyuki Hirota Tsutomu Ando Proceedings Editorial Board Yoshio Sakka Noriyuki Hirota Shigeru Horii Tsutomu Ando Conference photograph

Structure and shale gas production patterns from eastern Kentucky field

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shumaker, R.C.

Computer-derived subsurface structure, isopach, and gas-flow maps, based on 4000 drillers logs, have been generated for eastern Kentucky under a project sponsored by the Gas Research Institute. Structure maps show low-relief flextures related to basement structure. Some structures have been mapped at the surface, others have not. Highest final open-flow (fof) of shale gas from wells in Martin County follow a structural low between (basement) anticlines. From there, elevated gas flows (fof) extend westward along the Warfield monocline to Floyd County where the high flow (fof) trend extends southward along the Floyd County channel. In Knott County, the number ofmore » wells with high gas flow (fof) decreases abruptly. The center of highest gas flow (fof) in Floyd County spreads eastward to Pike County, forming a triangular shaped area of high production (fof). The center of highest gas flow (fof) is in an area where possible (basement) structure trends intersect and where low-relief surface folds (probably detached structure) were mapped and shown on the 1922 version of the Floyd County structure map. Modern regional maps, based on geophysical logs from widely spaced wells, do not define the low-relief structures that have been useful in predicting gas flow trends. Detailed maps based on drillers logs can be misleading unless carefully edited. Comparative analysis of high gas flows (fof) and 10-year cumulative production figures in a small area confirms that there is a relationship between gas flow (fof) values and long-term cumulative production.« less

Geology of the Cape Mendocino, Eureka, Garberville, and Southwestern Part of the Hayfork 30 x 60 Minute Quadrangles and Adjacent Offshore Area, Northern California

USGS Publications Warehouse

McLaughlin, Robert J.; Ellen, S.D.; Blake, M.C.; Jayko, Angela S.; Irwin, W.P.; Aalto, K.R.; Carver, G.A.; Clarke, S.H.; Barnes, J.B.; Cecil, J.D.; Cyr, K.A.

2000-01-01

Introduction These geologic maps and accompanying structure sections depict the geology and structure of much of northwestern California and the adjacent continental margin. The map area includes the Mendocino triple junction, which is the juncture of the North American continental plate with two plates of the Pacific ocean basin. The map area also encompasses major geographic and geologic provinces of northwestern California. The maps incorporate much previously unpublished geologic mapping done between 1980 and 1995, as well as published mapping done between about 1950 and 1978. To construct structure sections to mid-crustal depths, we integrate the surface geology with interpretations of crustal structure based on seismicity, gravity and aeromagnetic data, offshore structure, and seismic reflection and refraction data. In addition to describing major geologic and structural features of northwestern California, the geologic maps have the potential to address a number of societally relevant issues, including hazards from earthquakes, landslides, and floods and problems related to timber harvest, wildlife habitat, and changing land use. All of these topics will continue to be of interest in the region, as changing land uses and population density interact with natural conditions. In these interactions, it is critical that the policies and practices affecting man and the environment integrate an adequate understanding of the geology. This digital map database, compiled from previously published and unpublished data, and new mapping by the authors, represents the general distribution of bedrock and surficial deposits in the mapped area. Together with the accompanying text file (ceghmf.ps, ceghmf.pdf, ceghmf.txt), it provides current information on the geologic structure and stratigraphy of the area covered. The database delineates map units that are identified by general age and lithology following the stratigraphic nomenclature of the U.S. Geological Survey. The scale of the source maps limits the spatial resolution (scale) of the database to 1:100,000 or smaller.

Minerals yearbook: Mineral industries of Europe and central Eurasia. Volume 3. 1992 international review

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1992-01-01

Volume III, Minerals Yearbook -- International Review contains the latest available mineral data on more than 175 foreign countries and discusses the importance of minerals to the economies of these nations. Since the 1989 International Review, the volume has been presented as six reports. The report presents the Mineral Industries of Europe and Central Eurasia. The report incorporates location maps, industry structure tables, and an outlook section previously incorporated in the authors' Minerals Perspectives Series quinquennial regional books, which are being discontinued. This section of the Minerals Yearbook reviews the minerals industries of 45 countries: the 12 nations of themore » European Community (EC); 6 of the 7 nations of the European Free Trade Association (EFTA); Malta; the 11 Eastern European economies in transition (Albania, Bosnia and Hercegovina, Bulgaria, Croatia, Czechoslovakia, Hungary, Macedonia, Poland, Romania, Serbia and Montenegro, and Slovenia); and the countries of Central Eurasia (Armenia, Azerbaijan, Belarus, Estonia, Georgia, Kazakhstan, Kyrgystan, Latvia, Lithuania, Moldova, Russia, Tajikistan, Turkmenistan, Ukraine, and Uzbekistan).« less

LMSD: LIPID MAPS structure database

PubMed Central

Sud, Manish; Fahy, Eoin; Cotter, Dawn; Brown, Alex; Dennis, Edward A.; Glass, Christopher K.; Merrill, Alfred H.; Murphy, Robert C.; Raetz, Christian R. H.; Russell, David W.; Subramaniam, Shankar

2007-01-01

The LIPID MAPS Structure Database (LMSD) is a relational database encompassing structures and annotations of biologically relevant lipids. Structures of lipids in the database come from four sources: (i) LIPID MAPS Consortium's core laboratories and partners; (ii) lipids identified by LIPID MAPS experiments; (iii) computationally generated structures for appropriate lipid classes; (iv) biologically relevant lipids manually curated from LIPID BANK, LIPIDAT and other public sources. All the lipid structures in LMSD are drawn in a consistent fashion. In addition to a classification-based retrieval of lipids, users can search LMSD using either text-based or structure-based search options. The text-based search implementation supports data retrieval by any combination of these data fields: LIPID MAPS ID, systematic or common name, mass, formula, category, main class, and subclass data fields. The structure-based search, in conjunction with optional data fields, provides the capability to perform a substructure search or exact match for the structure drawn by the user. Search results, in addition to structure and annotations, also include relevant links to external databases. The LMSD is publicly available at PMID:17098933

Using concept mapping to evaluate knowledge structure in problem-based learning.

PubMed

Hung, Chia-Hui; Lin, Chen-Yung

2015-11-27

Many educational programs incorporate problem-based learning (PBL) to promote students' learning; however, the knowledge structure developed in PBL remains unclear. The aim of this study was to use concept mapping to generate an understanding of the use of PBL in the development of knowledge structures. Using a quasi-experimental study design, we employed concept mapping to illustrate the effects of PBL by examining the patterns of concepts and differences in the knowledge structures of students taught with and without a PBL approach. Fifty-two occupational therapy undergraduates were involved in the study and were randomly divided into PBL and control groups. The PBL group was given two case scenarios for small group discussion, while the control group continued with ordinary teaching and learning. Students were asked to make concept maps after being taught about knowledge structure. A descriptive analysis of the morphology of concept maps was conducted in order to compare the integration of the students' knowledge structures, and statistical analyses were done to understand the differences between groups. Three categories of concept maps were identified as follows: isolated, departmental, and integrated. The students in the control group constructed more isolated maps, while the students in the PBL group tended toward integrated mapping. Concept Relationships, Hierarchy Levels, and Cross Linkages in the concept maps were significantly greater in the PBL group; however, examples of concept maps did not differ significantly between the two groups. The data indicated that PBL had a strong effect on the acquisition and integration of knowledge. The important properties of PBL, including situational learning, problem spaces, and small group interactions, can help students to acquire more concepts, achieve an integrated knowledge structure, and enhance clinical reasoning.

Characterization and fine mapping of qkc7.03: a major locus for kernel cracking in maize.

PubMed

Yang, Mingtao; Chen, Lin; Wu, Xun; Gao, Xing; Li, Chunhui; Song, Yanchun; Zhang, Dengfeng; Shi, Yunsu; Li, Yu; Li, Yong-Xiang; Wang, Tianyu

2018-02-01

A major locus conferring kernel cracking in maize was characterized and fine mapped to an interval of 416.27 kb. Meanwhile, combining the results of transcriptomic analysis, the candidate gene was inferred. Seed development requires a proper structural and physiological balance between the maternal tissues and the internal structures of the seeds. In maize, kernel cracking is a disorder in this balance that seriously limits quality and yield and is characterized by a cracked pericarp at the kernel top and endosperm everting. This study elucidated the genetic basis and characterization of kernel cracking. Primarily, a near isogenic line (NIL) with a B73 background exhibited steady kernel cracking across environments. Therefore, deprived mapping populations were developed from this NIL and its recurrent parent B73. A major locus on chromosome 7, qkc7.03, was identified to be associated with the cracking performance. According to a progeny test of recombination events, qkc7.03 was fine mapped to a physical interval of 416.27 kb. In addition, obvious differences were observed in embryo development and starch granule arrangement within the endosperm between the NIL and its recurrent parent upon the occurrence of kernel cracking. Moreover, compared to its recurrent parent, the transcriptome of the NIL showed a significantly down-regulated expression of genes related to zeins, carbohydrate synthesis and MADS-domain transcription factors. The transcriptomic analysis revealed ten annotated genes within the target region of qkc7.03, and only GRMZM5G899476 was differently expressed between the NIL and its recurrent parent, indicating that this gene might be a candidate gene for kernel cracking. The results of this study facilitate the understanding of the potential mechanism underlying kernel cracking in maize.

Computation of statistical secondary structure of nucleic acids.

PubMed Central

Yamamoto, K; Kitamura, Y; Yoshikura, H

1984-01-01

This paper presents a computer analysis of statistical secondary structure of nucleic acids. For a given single stranded nucleic acid, we generated "structure map" which included all the annealing structures in the sequence. The map was transformed into "energy map" by rough approximation; here, the energy level of every pairing structure consisting of more than 2 successive nucleic acid pairs was calculated. By using the "energy map", the probability of occurrence of each annealed structure was computed, i.e., the structure was computed statistically. The basis of computation was the 8-queen problem in the chess game. The validity of our computer programme was checked by computing tRNA structure which has been well established. Successful application of this programme to small nuclear RNAs of various origins is demonstrated. PMID:6198622

The Structure-Mapping Engine: Algorithm and Examples.

ERIC Educational Resources Information Center

Falkenhainer, Brian; And Others

This description of the Structure-Mapping Engine (SME), a flexible, cognitive simulation program for studying analogical processing which is based on Gentner's Structure-Mapping theory of analogy, points out that the SME provides a "tool kit" for constructing matching algorithms consistent with this theory. This report provides: (1) a…

Mapping forest structure, species gradients and growth in an urban area using lidar and hyperspectral imagery

NASA Astrophysics Data System (ADS)

Gu, Huan

Urban forests play an important role in the urban ecosystem by providing a range of ecosystem services. Characterization of forest structure, species variation and growth in urban forests is critical for understanding the status, function and process of urban ecosystems, and helping maximize the benefits of urban ecosystems through management. The development of methods and applications to quantify urban forests using remote sensing data has lagged the study of natural forests due to the heterogeneity and complexity of urban ecosystems. In this dissertation, I quantify and map forest structure, species gradients and forest growth in an urban area using discrete-return lidar, airborne imaging spectroscopy and thermal infrared data. Specific objectives are: (1) to demonstrate the utility of leaf-off lidar originally collected for topographic mapping to characterize and map forest structure and associated uncertainties, including aboveground biomass, basal area, diameter, height and crown size; (2) to map species gradients using forest structural variables estimated from lidar and foliar functional traits, vegetation indices derived from AVIRIS hyperspectral imagery in conjunction with field-measured species data; and (3) to identify factors related to relative growth rates in aboveground biomass in the urban forests, and assess forest growth patterns across areas with varying degree of human interactions. The findings from this dissertation are: (1) leaf-off lidar originally acquired for topographic mapping provides a robust, potentially low-cost approach to quantify spatial patterns of forest structure and carbon stock in urban areas; (2) foliar functional traits and vegetation indices from hyperspectral data capture gradients of species distributions in the heterogeneous urban landscape; (3) species gradients, stand structure, foliar functional traits and temperature are strongly related to forest growth in the urban forests; and (4) high uncertainties in our ability to map forest structure, species gradient and growth rate occur in residential neighborhoods and along forest edges. Maps generated from this dissertation provide estimates of broad-scale spatial variations in forest structure, species distributions and growth to the city forest managers. The associated maps of uncertainty help managers understand the limitations of the maps and identify locations where the maps are more reliable and where more data are needed.

Nondestructive Evaluation of Advanced Materials with X-ray Phase Mapping

NASA Technical Reports Server (NTRS)

Hu, Zhengwei

2005-01-01

X-ray radiation has been widely used for imaging applications since Rontgen first discovered X-rays over a century ago. Its large penetration depth makes it ideal for the nondestructive visualization of the internal structure and/or defects of materials unobtainable otherwise. Currently used nondestructive evaluation (NDE) tools, X-ray radiography and tomography, are absorption-based, and work well in heavy-element materials where density or composition variations due to internal structure or defects are high enough to produce appreciable absorption contrast. However, in many cases where materials are light-weight and/or composites that have similar mass absorption coefficients, the conventional absorption-based X-ray methods for NDE become less useful. Indeed, the light-weight and ultra-high-strength requirements for the most advanced materials used or developed for current flight mission and future space exploration pose a great challenge to the standard NDE tools in that the absorption contrast arising from the internal structure of these materials is often too weak to be resolved. In this presentation, a solution to the problem, the use of phase information of X-rays for phase contrast X-ray imaging, will be discussed, along with a comparison between the absorption-based and phase-contrast imaging methods. Latest results on phase contrast X-ray imaging of lightweight Space Shuttle foam in 2D and 3D will be presented, demonstrating new opportunities to solve the challenging issues encountered in advanced materials development and processing.

Mapping International Cancer Activities – Global Cancer Project Map Launch

Cancer.gov

CGH’s Dr. Sudha Sivaram, Dr. Makeda Williams, and Ms. Kalina Duncan have partnered with Drs. Ami Bhatt and Franklin Huang at Global Oncology, Inc. (GO) to develop the Global Cancer Project Map - a web-based tool designed to facilitate cancer research and control activity planning.

Assessing Geographic Knowledge with Sketch Maps.

ERIC Educational Resources Information Center

Wise, Naomi; Kon, Jane Heckley

1990-01-01

Maintains that comparison of students' sketch maps at the beginning and end of the year can provide information on how student's representations of the world changes. Describes a study from the California International Studies Project (CISP) that provides an easy method for sorting and summarizing sketch map data. Illustrates the method with…

The Potential of Spaceborne Remote Sensing for Deriving Canopy Structure Metrics and Informing Biodiversity and Habitat Mapping

NASA Astrophysics Data System (ADS)

Goetz, S. J.; Dubayah, R.

2016-12-01

Research on characterization of canopy structure with remote sensing has exploded as airborne data sets have become more widely available to the biodiversity science and habitat management communities. While these advances are important in the context of increasing pressure on both habitat and wildlife, airborne data acquisitions are necessarily limited in geographic scope and thus in their general applicability to biome-scale biodiversity research initiatives, including international programs striving to implement the United Nations Convention on Biological Diversity (CBD) and the associated Aichi Biodiversity Targets. The lack of systematic metrics of canopy structure across large geographic domains also makes it difficult to implement the CBD Strategic Plan systematically across nations, as outlined in National Biodiversity Strategies and Action Plans. The Group on Earth Observations, Biodiversity Observation Network (GEO BON) has proposed a set of Essential Biodiversity Variables (EBVs) that could be used as a global-scale basis for biodiversity monitoring, but several of those EBVs are still limited by the availability of data on habitat 3D structure. Those limitations will be overcome in the near future with a suite of satellite missions that will provide an unprecedented level of active remote sensing measurements useful for deriving structure information, including Tandem-X, ICESat-2, BIOMASS and the Global Ecosystem Dynamics Investigation (GEDI). We will provide a brief overview of the rapid advance of measurements of canopy structure and the applications that have evolved in recent years in terms of 3D habitat characterization, species-specific habitat utilization, and the potential of these new space-based measurements. In this talk we will focus primarily on GEDI, a lidar mission to be installed on the International Space Station that is optimized for retrieving 3D canopy structure. GEDI and the other new missions will provide long-desired consistent and systematic information on EBVs from space, and thereby facilitate the implementation of international biodiversity policy objectives.

Does Size Matter? The Multipolar International Landscape of Nanoscience

PubMed Central

Jensen, Pablo; Kreimer, Pablo

2016-01-01

How do different countries tackle nanoscience research? Are all countries similar except for a trivial size effect, as science is often assumed to be universal? Or does size dictate large differences, as large countries are able to develop activities in all directions of research, while small countries have to specialize in some specific niches? Alternatively, is size irrelevant, as all countries have followed different historical paths, leading to different patterns of specialisation? Here, we develop an original method that uses a bottom-up definition of scientific subfields to map the international structure of any scientific field. Our analysis shows that nanoscience research does not show a universal pattern of specialisation, homothetic of that of a single global leader (e.g., the United States). Instead, we find a multipolar world, with four main ways of doing nanosciences. PMID:27992439

Does Size Matter? The Multipolar International Landscape of Nanoscience.

PubMed

Levin, Luciano; Jensen, Pablo; Kreimer, Pablo

2016-01-01

How do different countries tackle nanoscience research? Are all countries similar except for a trivial size effect, as science is often assumed to be universal? Or does size dictate large differences, as large countries are able to develop activities in all directions of research, while small countries have to specialize in some specific niches? Alternatively, is size irrelevant, as all countries have followed different historical paths, leading to different patterns of specialisation? Here, we develop an original method that uses a bottom-up definition of scientific subfields to map the international structure of any scientific field. Our analysis shows that nanoscience research does not show a universal pattern of specialisation, homothetic of that of a single global leader (e.g., the United States). Instead, we find a multipolar world, with four main ways of doing nanosciences.

Mapping Risks of Indonesian Tuna Supply Chain

NASA Astrophysics Data System (ADS)

Karningsih, P. D.; Anggrahini, D.; Kurniati, N.; Suef, M.; Fachrur, A. R.; Syahroni, N.

2018-04-01

Due to its high economic value and is produced by many countries, Tuna is considered as one of the world’s popular fish. Demand for Tuna species are very high and it usually sells in three form: fresh, frozen or canned. Competition in Tuna trading is challengin with the potential risk of price and supply fluctuations. With recent focus of Indonesia government that see the future of Indonesia civilization depend on the oceans and as the three biggest Tuna producing country, Ministry of Marine Affairs and Fisheries should ensure sustainability and competitiveness of Indonesian tuna. Therefore, there is a great need to develop a proper and effective strategy to manage potential risks in Indonesian Tuna supply chain. This paper is aimed at identifying and mapping potential Tuna supply chain risks and its interrelationships that would assist government in determining proper strategies to manage Indonesian Tuna. A framework for identifying Tuna supply chain risks is proposed. Generic risk structure of Supply Chain Risk Identification System is adopted and modified to match with particular object, which is Indonesian Tuna. The proposed model consists of hierarchical and causal structure that encompass potential risks of Tuna supply chain operations from fishing, trading, processing and distribution. The causal structure consist of risk events and its risk agents which is the cause of risk events. To ensure the root cause of risk events are identified properly, five why’s analysis is utilized to obtain risk agents. This proposed model also captures risk interrelationship between internal and external environment of Tuna supply chain. Preliminary result of this study identifies 15 risk events and 13 risk factors on fishing and trading operations and maps their interrelationships.

Magnetic map of the Irish Hills and surrounding areas, San Luis Obispo County, central California

USGS Publications Warehouse

Langenheim, V.E.; Watt, J.T.; Denton, K.M.

2012-01-01

A magnetic map of the Irish Hills and surrounding areas was created as part of a cooperative research and development agreement with the Pacific Gas and Electric Company and is intended to promote further understanding of the areal geology and structure by serving as a basis for geophysical interpretations and by supporting geological mapping, mineral and water resource investigations, and other topical studies. Local spatial variations in the Earth's magnetic field (evident as anomalies on magnetic maps) reflect the distribution of magnetic minerals, primarily magnetite, in the underlying rocks. In many cases the volume content of magnetic minerals can be related to rock type, and abrupt spatial changes in the amount of magnetic minerals can be related to either lithologic or structural boundaries. Magnetic susceptibility measurements from the area indicate that bodies of serpentinite and other mafic and ultramafic rocks tend to produce the most intense magnetic anomalies, but such generalizations must be applied with caution because some sedimentary units also can produce measurable magnetic anomalies. Remanent magnetization does not appear to be a significant source for magnetic anomalies because it is an order of magnitude less than the induced magnetization. The map is a mosaic of three separate surveys collected by (1) fixed-wing aircraft at a nominal height of 305 m, (2) by boat with the sensor at sea level, and (3) by helicopter. The helicopter survey was flown by New-Sense Geophysics in October 2009 along flight lines spaced 150-m apart and at a nominal terrain clearance of 50 to 100 m. Tie lines were flown 1,500-m apart. Data were adjusted for lag error and diurnal field variations. Further processing included microleveling using the tie lines and subtraction of the reference field defined by International Geomagnetic Reference Field (IGRF) 2005 extrapolated to August 1, 2008.

The nappes of the Lepontine dome: the influence of tectonic inheritance on their deformation style

NASA Astrophysics Data System (ADS)

Schenker, Filippo Luca; Ambrosi, Christian; Scapozza, Cristian; Czerki, Dorota; Castelletti, Claudio; Maino, Matteo; Gouffon, Yves

2017-04-01

The Lepontine dome exposes the tectonostratigraphy of the Central Alps, from bottom-to-top, the subpenninic gneissic nappes of the Leventina, Simano, Adula/Cima-Lunga and Maggia. These units were part of a post-Variscan gneissic crust, which was intensely intruded by several generations of granitoids forming laccoliths and dikes of different shapes and sizes within paragneisses, augengneisses and amphibolites. During the Alpine orogenic cycle this initial and complex geological architecture was reshaped into a fold and thrust belt. We present the effect of these initial rheological anomalies along the Leventina, Simano and Adula/Cima-Lunga units through the geological map of the Osogna sheet (Swiss National Map no. 1293,1:25'000) together with structural and metamorphic data. The geological map shows that the Simano and Adula/Cima-Lunga units have an internal and lateral lithological variation at different scales as illustrated by the geological cross-sections. All lithologies present a penetrative amphibolite-facies foliation, which can vary in intensity among the rock-types. On the foliation plane a mineral and stretching lineation is visible dipping NW or SE, depending on the plane dip direction. The kinematic analysis indicates a top-to-the NW shearing. Despite this consistent structural data showing a regional dominant fabric, the folds (generally with a fold-axis parallel to the lineation) show different styles, depending on the thickness and the rock-type of the folded horizon and matrix, do not form laterally continuous structures and often are not cylindrical. As a consequence, such structures are interpreted as local perturbation rather than structures of regional importance. Furthermore, the Leventina and the Simano boundary is locally incongruent with the tectonic contact of the published maps. The amphibolite and paragneisses, used in the past as nappe divider, result to be deformed magmatic xenoliths. Therefore we present evidence (i) of a bottom-to-top top-to-the-foreland deformation gradient between the Leventina and Adula/Cima-Lunga units, (ii) within this shearing, the inherited rheological heterogeneities in the units lead to non-coaxial ductile deformation complicating the tectonic understanding and (iii) the boundary between the Leventina and the Simano units was a magmatic contact, questioning the allochthonous character of the Simano unit.

Volcanic hazard management in dispersed volcanism areas

NASA Astrophysics Data System (ADS)

Marrero, Jose Manuel; Garcia, Alicia; Ortiz, Ramon

2014-05-01

Traditional volcanic hazard methodologies were developed mainly to deal with the big stratovolcanoes. In such type of volcanoes, the hazard map is an important tool for decision-makers not only during a volcanic crisis but also for territorial planning. According to the past and recent eruptions of a volcano, all possible volcanic hazards are modelled and included in the hazard map. Combining the hazard map with the Event Tree the impact area can be zoned and defining the likely eruptive scenarios that will be used during a real volcanic crisis. But in areas of disperse volcanism is very complex to apply the same volcanic hazard methodologies. The event tree do not take into account unknown vents, because the spatial concepts included in it are only related with the distance reached by volcanic hazards. The volcanic hazard simulation is also difficult because the vent scatter modifies the results. The volcanic susceptibility try to solve this problem, calculating the most likely areas to have an eruption, but the differences between low and large values obtained are often very small. In these conditions the traditional hazard map effectiveness could be questioned, making necessary a change in the concept of hazard map. Instead to delimit the potential impact areas, the hazard map should show the expected behaviour of the volcanic activity and how the differences in the landscape and internal geo-structures could condition such behaviour. This approach has been carried out in La Palma (Canary Islands), combining the concept of long-term hazard map with the short-term volcanic scenario to show the expected volcanic activity behaviour. The objective is the decision-makers understand how a volcanic crisis could be and what kind of mitigation measurement and strategy could be used.

Map and database of Quaternary faults in Venezuela and its offshore regions

USGS Publications Warehouse

Audemard, F.A.; Machette, M.N.; Cox, J.W.; Dart, R.L.; Haller, K.M.

2000-01-01

As part of the International Lithosphere Program’s “World Map of Major Active Faults,” the U.S. Geological Survey is assisting in the compilation of a series of digital maps of Quaternary faults and folds in Western Hemisphere countries. The maps show the locations, ages, and activity rates of major earthquake-related features such as faults and fault-related folds. They are accompanied by databases that describe these features and document current information on their activity in the Quaternary. The project is a key part of the Global Seismic Hazards Assessment Program (ILP Project II-0) for the International Decade for Natural Hazard Disaster Reduction.The project is sponsored by the International Lithosphere Program and funded by the USGS’s National Earthquake Hazards Reduction Program. The primary elements of the project are general supervision and interpretation of geologic/tectonic information, data compilation and entry for fault catalog, database design and management, and digitization and manipulation of data in †ARCINFO. For the compilation of data, we engaged experts in Quaternary faulting, neotectonics, paleoseismology, and seismology.

Timed activity performance in persons with upper limb amputation: A preliminary study.

PubMed

Resnik, Linda; Borgia, Mathew; Acluche, Frantzy

55 subjects with upper limb amputation were administered the T-MAP twice within one week. To develop a timed measure of activity performance for persons with upper limb amputation (T-MAP); examine the measure's internal consistency, test-retest reliability and validity; and compare scores by prosthesis use. Measures of activity performance for persons with upper limb amputation are needed The time required to perform daily activities is a meaningful metric that implication for participation in life roles. Internal consistency and test-retest reliability were evaluated. Construct validity was examined by comparing scores by amputation level. Exploratory analyses compared sub-group scores, and examined correlations with other measures. Scale alpha was 0.77, ICC was 0.93. Timed scores differed by amputation level. Subjects using a prosthesis took longer to perform all tasks. T-MAP was not correlated with other measures of dexterity or activity, but was correlated with pain for non-prosthesis users. The timed scale had adequate internal consistency and excellent test-retest reliability. Analyses support reliability and construct validity of the T-MAP. 2c "outcomes" research. Published by Elsevier Inc.

The Receptor-Binding Domain in the VP1u Region of Parvovirus B19.

PubMed

Leisi, Remo; Di Tommaso, Chiarina; Kempf, Christoph; Ros, Carlos

2016-02-24

Parvovirus B19 (B19V) is known as the human pathogen causing the mild childhood disease erythema infectiosum. B19V shows an extraordinary narrow tissue tropism for erythroid progenitor cells in the bone marrow, which is determined by a highly restricted uptake. We have previously shown that the specific internalization is mediated by the interaction of the viral protein 1 unique region (VP1u) with a yet unknown cellular receptor. To locate the receptor-binding domain (RBD) within the VP1u, we analyzed the effect of truncations and mutations on the internalization capacity of the recombinant protein into UT7/Epo cells. Here we report that the N-terminal amino acids 5-80 of the VP1u are necessary and sufficient for cellular binding and internalization; thus, this N-terminal region represents the RBD required for B19V uptake. Using site-directed mutagenesis, we further identified a cluster of important amino acids playing a critical role in VP1u internalization. In silico predictions and experimental results suggest that the RBD is structured as a rigid fold of three α-helices. Finally, we found that dimerization of the VP1u leads to a considerably enhanced cellular binding and internalization. Taken together, we identified the RBD that mediates B19V uptake and mapped functional and structural motifs within this sequence. The findings reveal insights into the uptake process of B19V, which contribute to understand the pathogenesis of the infection and the neutralization of the virus by the immune system.

The Receptor-Binding Domain in the VP1u Region of Parvovirus B19

PubMed Central

Leisi, Remo; Di Tommaso, Chiarina; Kempf, Christoph; Ros, Carlos

2016-01-01

Parvovirus B19 (B19V) is known as the human pathogen causing the mild childhood disease erythema infectiosum. B19V shows an extraordinary narrow tissue tropism for erythroid progenitor cells in the bone marrow, which is determined by a highly restricted uptake. We have previously shown that the specific internalization is mediated by the interaction of the viral protein 1 unique region (VP1u) with a yet unknown cellular receptor. To locate the receptor-binding domain (RBD) within the VP1u, we analyzed the effect of truncations and mutations on the internalization capacity of the recombinant protein into UT7/Epo cells. Here we report that the N-terminal amino acids 5–80 of the VP1u are necessary and sufficient for cellular binding and internalization; thus, this N-terminal region represents the RBD required for B19V uptake. Using site-directed mutagenesis, we further identified a cluster of important amino acids playing a critical role in VP1u internalization. In silico predictions and experimental results suggest that the RBD is structured as a rigid fold of three α-helices. Finally, we found that dimerization of the VP1u leads to a considerably enhanced cellular binding and internalization. Taken together, we identified the RBD that mediates B19V uptake and mapped functional and structural motifs within this sequence. The findings reveal insights into the uptake process of B19V, which contribute to understand the pathogenesis of the infection and the neutralization of the virus by the immune system. PMID:26927158

2D and 3D visualization methods of endoscopic panoramic bladder images

NASA Astrophysics Data System (ADS)

Behrens, Alexander; Heisterklaus, Iris; Müller, Yannick; Stehle, Thomas; Gross, Sebastian; Aach, Til

2011-03-01

While several mosaicking algorithms have been developed to compose endoscopic images of the internal urinary bladder wall into panoramic images, the quantitative evaluation of these output images in terms of geometrical distortions have often not been discussed. However, the visualization of the distortion level is highly desired for an objective image-based medical diagnosis. Thus, we present in this paper a method to create quality maps from the characteristics of transformation parameters, which were applied to the endoscopic images during the registration process of the mosaicking algorithm. For a global first view impression, the quality maps are laid over the panoramic image and highlight image regions in pseudo-colors according to their local distortions. This illustration supports then surgeons to identify geometrically distorted structures easily in the panoramic image, which allow more objective medical interpretations of tumor tissue in shape and size. Aside from introducing quality maps in 2-D, we also discuss a visualization method to map panoramic images onto a 3-D spherical bladder model. Reference points are manually selected by the surgeon in the panoramic image and the 3-D model. Then the panoramic image is mapped by the Hammer-Aitoff equal-area projection onto the 3-D surface using texture mapping. Finally the textured bladder model can be freely moved in a virtual environment for inspection. Using a two-hemisphere bladder representation, references between panoramic image regions and their corresponding space coordinates within the bladder model are reconstructed. This additional spatial 3-D information thus assists the surgeon in navigation, documentation, as well as surgical planning.

Mapping Biomass for REDD in the Largest Forest of Central Africa: the Democratic Republic of Congo

NASA Astrophysics Data System (ADS)

Shapiro, Aurelie; Saatchi, Sassan

2014-05-01

With the support of the International Climate Initiative (ICI) of the Federal Ministry of the Environment, Conservation, and Nuclear Security, the implementation of the German Development Bank KfW, the World Wide Fund for Nature (WWF) Germany, the University of California Los Angeles (UCLA) and local DRC partners will produce a national scale biomass map for the entire forest coverage of the Democratic Republic of Congo (DRC) along with feasibility assessments of different forest protection measures within a framework of a REDD+ model project. The « Carbon Map and Model (CO2M&M) » project will produce a national forest biomass map for the DRC, which will enable quantitative assessments of carbon stocks and emissions in the largest forest of the Congo Basin. This effort will support the national REDD (Reducing Emissions from Deforestation and Degradation) program in DRC, which plays a major role in sustainable development and poverty alleviation. This map will be developed from field data, complemented by airborne LiDAR (Light Detection and Ranging) and aerial photos, systematically sampled throughout the forests of the DRC and up-scaled to satellite images to accurately estimate carbon content in all forested areas. The second component of the project is to develop specific approaches for model REDD projects in key landscapes. This project represents the largest LiDAR-derived mapping effort in Africa, under unprecedented logistical constraints, which will provide one of the poorest nations in the world with the richest airborne and satellites derived datasets for analyzing forest structure, biomass and biodiversity.

Promoting Inclusivity in STEM through Active Recruiting and Mentoring: The Pre-Major in Astronomy Program (Pre-MAP) at the University of Washington

NASA Astrophysics Data System (ADS)

Schwieterman, Edward; Binder, Breanna A.; Pre-Major in Astronomy Program

2016-01-01

The Pre-Major in Astronomy Program (Pre-MAP) is a research and mentoring program for entering undergraduate students offered by the University of Washington Astronomy Department since 2005. The primary goal of Pre-MAP is to recruit and retain students from groups traditionally underrepresented in science, technology, engineering, and mathematics (STEM) through early exposure to guided research projects. The Pre-MAP seminar is the core component of the program and offers instruction in computing skills, data manipulation, science writing, statistical analysis, and scientific speaking and presentation skills. Students choose research projects proposed by faculty, post-docs and graduate students in areas related to astrophysics, planetary science, and astrobiology. Pre-MAP has been successful in retaining underrepresented students in STEM fields relative to the broader UW population, and we've found these students are more likely to graduate and excel academically than their peers. As of fall 2015, more than one hundred students have taken the Pre-MAP seminar, and both internal and external evaluations have shown that all groups of participating students report an increased interest in astronomy and science careers at the end of the seminar. This talk will provide an overview of the program and the structure of the core seminar. In particular, the talk will focus on additions and revisions to the seminar course over the last few years, such as the introduction of a public speaking coach, career and internship modules, and the formalization of external lab tours.

Mapping transiently formed and sparsely populated conformations on a complex energy landscape.

PubMed

Wang, Yong; Papaleo, Elena; Lindorff-Larsen, Kresten

2016-08-23

Determining the structures, kinetics, thermodynamics and mechanisms that underlie conformational exchange processes in proteins remains extremely difficult. Only in favourable cases is it possible to provide atomic-level descriptions of sparsely populated and transiently formed alternative conformations. Here we benchmark the ability of enhanced-sampling molecular dynamics simulations to determine the free energy landscape of the L99A cavity mutant of T4 lysozyme. We find that the simulations capture key properties previously measured by NMR relaxation dispersion methods including the structure of a minor conformation, the kinetics and thermodynamics of conformational exchange, and the effect of mutations. We discover a new tunnel that involves the transient exposure towards the solvent of an internal cavity, and show it to be relevant for ligand escape. Together, our results provide a comprehensive view of the structural landscape of a protein, and point forward to studies of conformational exchange in systems that are less characterized experimentally.

Report on the Second International Workshop on Human Chromosome 9

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kwiatkowski, D.J.; Armour, J.; Bale, A.E.

The Second International Workshop on Human Chromosome 9 was held in Chatham, Massachusetts on April 18--20, 1993. Fifty-three abstracts were received and the data presented on posters. The purpose of the meeting was to bring together all interested investigators working on the map of chromosome 9, many of whom had disease-specific interests. After a brief presentation of interests and highlighted results, the meeting broke up into the following subgroups for production of consensus maps: 9p; 9cen-q32; 9q32 ter. A global mapping group also met. Reports of each of these working groups is presented in the summary.

Semi-automatic mapping of geological Structures using UAV-based photogrammetric data: An image analysis approach

NASA Astrophysics Data System (ADS)

Vasuki, Yathunanthan; Holden, Eun-Jung; Kovesi, Peter; Micklethwaite, Steven

2014-08-01

Recent advances in data acquisition technologies, such as Unmanned Aerial Vehicles (UAVs), have led to a growing interest in capturing high-resolution rock surface images. However, due to the large volumes of data that can be captured in a short flight, efficient analysis of this data brings new challenges, especially the time it takes to digitise maps and extract orientation data. We outline a semi-automated method that allows efficient mapping of geological faults using photogrammetric data of rock surfaces, which was generated from aerial photographs collected by a UAV. Our method harnesses advanced automated image analysis techniques and human data interaction to rapidly map structures and then calculate their dip and dip directions. Geological structures (faults, joints and fractures) are first detected from the primary photographic dataset and the equivalent three dimensional (3D) structures are then identified within a 3D surface model generated by structure from motion (SfM). From this information the location, dip and dip direction of the geological structures are calculated. A structure map generated by our semi-automated method obtained a recall rate of 79.8% when compared against a fault map produced using expert manual digitising and interpretation methods. The semi-automated structure map was produced in 10 min whereas the manual method took approximately 7 h. In addition, the dip and dip direction calculation, using our automated method, shows a mean±standard error of 1.9°±2.2° and 4.4°±2.6° respectively with field measurements. This shows the potential of using our semi-automated method for accurate and efficient mapping of geological structures, particularly from remote, inaccessible or hazardous sites.

Evidence for large inversion polymorphisms in the human genome from HapMap data

PubMed Central

Bansal, Vikas; Bashir, Ali; Bafna, Vineet

2007-01-01

Knowledge about structural variation in the human genome has grown tremendously in the past few years. However, inversions represent a class of structural variation that remains difficult to detect. We present a statistical method to identify large inversion polymorphisms using unusual Linkage Disequilibrium (LD) patterns from high-density SNP data. The method is designed to detect chromosomal segments that are inverted (in a majority of the chromosomes) in a population with respect to the reference human genome sequence. We demonstrate the power of this method to detect such inversion polymorphisms through simulations done using the HapMap data. Application of this method to the data from the first phase of the International HapMap project resulted in 176 candidate inversions ranging from 200 kb to several megabases in length. Our predicted inversions include an 800-kb polymorphic inversion at 7p22, a 1.1-Mb inversion at 16p12, and a novel 1.2-Mb inversion on chromosome 10 that is supported by the presence of two discordant fosmids. Analysis of the genomic sequence around inversion breakpoints showed that 11 predicted inversions are flanked by pairs of highly homologous repeats in the inverted orientation. In addition, for three candidate inversions, the inverted orientation is represented in the Celera genome assembly. Although the power of our method to detect inversions is restricted because of inherently noisy LD patterns in population data, inversions predicted by our method represent strong candidates for experimental validation and analysis. PMID:17185644

The Structure of Solar Active Regions

NASA Astrophysics Data System (ADS)

Vourlidas, A.; Bastian, T. S.

1992-05-01

In past years, x-ray observations of solar active regions have lead to the expectation of greater brightness temperatures at radio wavelengths than those typically observed. It has been suggested that cool plasma in the corona along the line of sight attenuates radio emission via free-free absorption. If such plasma is present, it has consequences for both the microwave spectrum and its polarization properties. In order to test these ideas, high quality radio and x-ray maps are required. We present a comprehensive set of observations of a large solar active region (NOAO/USAF number 5131) made during the IAU sanctioned International Solar Month in September, 1988. The VLA was used to image the Sun in the 90, 20, 6 and 3.6 cm bands between 1--4 September. To improve the image quality we used the technique of frequency synthesis at 3.6, 6 and 20 cm. The final maps are among the best in dynamic range yet obtained. In addition to the radio maps, the data base includes images from the SMM XRP in Fe XVII, magnetograms, and Hα observations. We reconcile the x-ray and radio observations with a simple model which differs somewhat from past models. Rather than relying on a screen of cool plasma between the source and the observer, we take explicit account of the highly inhomogeneous structure of solar active regions. We briefly compare and contrast the consequences of this model with existing models.

NOAA Office of Exploration and Research > About OER > Strategic Plan

Science.gov Websites

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NOAA Office of Exploration and Research > About OER > Overview

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NOAA Office of Exploration and Research > About OER > Contact Us

Science.gov Websites

Organization Guiding Documents Organizational Structure Map of Staff and Affiliate Locations Strategic Plan Media News Room OER Symposium Overview Organization Guiding Documents Organizational Structure Map of Contact Us Home About OER Overview Organization Guiding Documents Organizational Structure Map of Staff

NOAA Office of Exploration and Research > About OER > Program Review

Science.gov Websites

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Implementation of structure-mapping inference by event-file binding and action planning: a model of tool-improvisation analogies.

PubMed

Fields, Chris

2011-03-01

Structure-mapping inferences are generally regarded as dependent upon relational concepts that are understood and expressible in language by subjects capable of analogical reasoning. However, tool-improvisation inferences are executed by members of a variety of non-human primate and other species. Tool improvisation requires correctly inferring the motion and force-transfer affordances of an object; hence tool improvisation requires structure mapping driven by relational properties. Observational and experimental evidence can be interpreted to indicate that structure-mapping analogies in tool improvisation are implemented by multi-step manipulation of event files by binding and action-planning mechanisms that act in a language-independent manner. A functional model of language-independent event-file manipulations that implement structure mapping in the tool-improvisation domain is developed. This model provides a mechanism by which motion and force representations commonly employed in tool-improvisation structure mappings may be sufficiently reinforced to be available to inwardly directed attention and hence conceptualization. Predictions and potential experimental tests of this model are outlined.

Mapping edge-based traffic measurements onto the internal links in MPLS network

NASA Astrophysics Data System (ADS)

Zhao, Guofeng; Tang, Hong; Zhang, Yi

2004-09-01

Applying multi-protocol label switching techniques to IP-based backbone for traffic engineering goals has shown advantageous. Obtaining a volume of load on each internal link of the network is crucial for traffic engineering applying. Though collecting can be available for each link, such as applying traditional SNMP scheme, the approach may cause heavy processing load and sharply degrade the throughput of the core routers. Then monitoring merely at the edge of the network and mapping the measurements onto the core provides a good alternative way. In this paper, we explore a scheme for traffic mapping with edge-based measurements in MPLS network. It is supposed that the volume of traffic on each internal link over the domain would be mapped onto by measurements available only at ingress nodes. We apply path-based measurements at ingress nodes without enabling measurements in the core of the network. We propose a method that can infer a path from the ingress to the egress node using label distribution protocol without collecting routing data from core routers. Based on flow theory and queuing theory, we prove that our approach is effective and present the algorithm for traffic mapping. We also show performance simulation results that indicate potential of our approach.

Diffraction Contrast Tomography: A Novel 3D Polycrystalline Grain Imaging Technique

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kuettner, Lindsey Ann

2017-06-06

Diffraction contrast tomography (DCT) is a non-destructive way of imaging microstructures of polycrystalline materials such as metals or crystalline organics. It is a useful technique to map 3D grain structures as well as providing crystallographic information such as crystal orientation, grain shape, and strain. Understanding the internal microstructure of a material is important in understanding the bulk material properties. This report gives a general overview of the similar techniques, DCT data acquisition, and analysis processes. Following the short literature review, potential work and research at Los Alamos National Laboratory (LANL) is discussed.

Structure-function analysis of the extracellular domain of the pneumococcal cell division site positioning protein MapZ

NASA Astrophysics Data System (ADS)

Manuse, Sylvie; Jean, Nicolas L.; Guinot, Mégane; Lavergne, Jean-Pierre; Laguri, Cédric; Bougault, Catherine M.; Vannieuwenhze, Michael S.; Grangeasse, Christophe; Simorre, Jean-Pierre

2016-06-01

Accurate placement of the bacterial division site is a prerequisite for the generation of two viable and identical daughter cells. In Streptococcus pneumoniae, the positive regulatory mechanism involving the membrane protein MapZ positions precisely the conserved cell division protein FtsZ at the cell centre. Here we characterize the structure of the extracellular domain of MapZ and show that it displays a bi-modular structure composed of two subdomains separated by a flexible serine-rich linker. We further demonstrate in vivo that the N-terminal subdomain serves as a pedestal for the C-terminal subdomain, which determines the ability of MapZ to mark the division site. The C-terminal subdomain displays a patch of conserved amino acids and we show that this patch defines a structural motif crucial for MapZ function. Altogether, this structure-function analysis of MapZ provides the first molecular characterization of a positive regulatory process of bacterial cell division.

An unbiased adaptive sampling algorithm for the exploration of RNA mutational landscapes under evolutionary pressure.

PubMed

Waldispühl, Jérôme; Ponty, Yann

2011-11-01

The analysis of the relationship between sequences and structures (i.e., how mutations affect structures and reciprocally how structures influence mutations) is essential to decipher the principles driving molecular evolution, to infer the origins of genetic diseases, and to develop bioengineering applications such as the design of artificial molecules. Because their structures can be predicted from the sequence data only, RNA molecules provide a good framework to study this sequence-structure relationship. We recently introduced a suite of algorithms called RNAmutants which allows a complete exploration of RNA sequence-structure maps in polynomial time and space. Formally, RNAmutants takes an input sequence (or seed) to compute the Boltzmann-weighted ensembles of mutants with exactly k mutations, and sample mutations from these ensembles. However, this approach suffers from major limitations. Indeed, since the Boltzmann probabilities of the mutations depend of the free energy of the structures, RNAmutants has difficulties to sample mutant sequences with low G+C-contents. In this article, we introduce an unbiased adaptive sampling algorithm that enables RNAmutants to sample regions of the mutational landscape poorly covered by classical algorithms. We applied these methods to sample mutations with low G+C-contents. These adaptive sampling techniques can be easily adapted to explore other regions of the sequence and structural landscapes which are difficult to sample. Importantly, these algorithms come at a minimal computational cost. We demonstrate the insights offered by these techniques on studies of complete RNA sequence structures maps of sizes up to 40 nucleotides. Our results indicate that the G+C-content has a strong influence on the size and shape of the evolutionary accessible sequence and structural spaces. In particular, we show that low G+C-contents favor the apparition of internal loops and thus possibly the synthesis of tertiary structure motifs. On the other hand, high G+C-contents significantly reduce the size of the evolutionary accessible mutational landscapes.

Cross-correlation between the 170 GHz survey map and the COBE differential microwave radiometer first-year maps

NASA Technical Reports Server (NTRS)

Ganga, Ken; Cheng, ED; Meyer, Stephan; Page, Lyman

1993-01-01

This letter describes results of a cross-correlation between the 170 GHz partial-sky survey, made with a 3.8 deg beam balloon-borne instrument, and the COBE DMR 'Fit Technique' reduced galaxy all-sky map with a beam of 7 deg. The strong correlation between the data sets implies that the observed structure is consistent with thermal variations in a 2.7 K emitter. A chi-square analysis applied to the correlation function rules out the assumption that there is no structure in either of the two maps. A second test shows that if the DMR map has structure but the 170 GHz map does not, the probability of obtaining the observed correlation is small. Further analyses support the assumption that both maps have structure and that the 170 GHz-DMR cross-correlation is consistent with the analogous DMR correlation function. Maps containing various combinations of noise and Harrison-Zel'dovich power spectra are simulated and correlated to reinforce the result. The correlation provides compelling evidence that both instruments have observed fluctuations consistent with anisotropies in the cosmic microwave background.

Paleostress Analysis with Reflection Seismic Data: Example from the Songliao Basin, Northeast China

NASA Astrophysics Data System (ADS)

Liu, G.; Persaud, P.; Zhang, Y.

2017-12-01

Currently paleostress inversion using fault-slip data is a well established approach. However, the deformation history contained in folds has not yet been fully utilized to determine the paleostress field. By applying a 2D FFT-based algorithm to a structure or isopach map derived from reflection seismic data, we find a new way of exploiting the information preserved in folds to determine the paleostress. Our method requires that the strata have a large areal extent and are well preserved. After pre-processing the maps, we find that in the frequency-wavenumber (F-K) domain, folds with similar strikes are grouped into spectrum belts. Each belt parallels the short axis of the fold group and can therefore indicate the direction of the associated maximum horizontal stress. Some information on the relative chronology of stresses can be deduced by comparing the structure and isopach spectrum maps, e.g., if the structure spectrum map has one more spectrum belt than that of the isopach map (an approximate paleo-structure map of the corresponding stratum), we can conclude that the indicated stress postdated the deposition of the stratum. We selected three Late Cretaceous strata from a 3D seismic survey located in the intracontinental Songliao Basin, northeast China. The Songliao has experienced four episodes of deformation: mantle upwelling, rifting, postrift thermal subsidence and structural inversion (Feng et al., 2009). The selected strata were deposited during the third stage. Three structure and two isopach maps were decomposed in the F-K domain. Spectral analysis of the lower isopach map shows eight paleostress directions. We also identify a ninth paleostress in addition to the previous eight from the structure maps and the upper isopach map. The eight stress directions that exist in both the isopach and structure maps may have been active throughout the time period spanned by the strata. We interpret the ninth paleostress as being active after the deposition of the lower stratum. The derived paleostress field fits well with the interpretations of other workers and provides more accurate stress directions and chronology. We further apply this technique to the Central Sichuan basin, southwest China, and confirm the multi-directional compressional tectonics of that basin.

NREL: International Activities - Pakistan Resource Maps

Science.gov Websites

. The high-resolution (1-km) annual wind power maps were developed using a numerical modeling approach along with NREL's empirical validation methodology. The high-resolution (10-km) annual and seasonal KB) | High-Res (ZIP 281 KB) 40-km Resolution Annual Maps (Direct) Low-Res (JPG 156 KB) | High-Res

Estimating missing hourly climatic data using artificial neural network for energy balance based ET mapping applications

USDA-ARS?s Scientific Manuscript database

Remote sensing based evapotranspiration (ET) mapping has become an important tool for water resources management at a regional scale. Accurate hourly climatic data and reference ET are crucial input for successfully implementing remote sensing based ET models such as Mapping ET with internal calibra...

Pest risk maps for invasive alien species: a roadmap for improvement

Treesearch

Robert C. Venette; Darren J. Kriticos; Roger D. Magarey; Frank H. Koch; Richard H.A. Baker; Susan P. Worner; Nadilia N. Gomez Raboteaux; Daniel W. McKenney; Erhard J. Dobesberger; Denys Yemshanov; Paul J. De Barro; William D. Hutchison; Glenn Fowler; Tom M. Kalaris; John Pedlar

2010-01-01

Pest risk maps are powerful visual communication tools to describe where invasive alien species might arrive, establish, spread, or cause harmful impacts. These maps inform strategic and tactical pest management decisions, such as potential restrictions on international trade or the design of pest surveys and domestic quarantines. Diverse methods are available to...

Mapping Participation in Situated Language Learning

ERIC Educational Resources Information Center

Groves, Olivia; Verenikina, Irina; Chen, Honglin

2016-01-01

Research on the international student experience in Australia has highlighted the challenges that international students face when obtaining tertiary qualifications in an Australian university [AEI. (2012). "Student voices: Enhancing the experience of international students in Australia." Canberra, Australia: Australian Education…

Assortative mating and fragmentation within dog breeds.

PubMed

Björnerfeldt, Susanne; Hailer, Frank; Nord, Maria; Vilà, Carles

2008-01-28

There are around 400 internationally recognized dog breeds in the world today, with a remarkable diversity in size, shape, color and behavior. Breeds are considered to be uniform groups with similar physical characteristics, shaped by selection rooted in human preferences. This has led to a large genetic difference between breeds and a large extent of linkage disequilibrium within breeds. These characteristics are important for association mapping of candidate genes for diseases and therefore make dogs ideal models for gene mapping of human disorders. However, genetic uniformity within breeds may not always be the case. We studied patterns of genetic diversity within 164 poodles and compared it to 133 dogs from eight other breeds. Our analyses revealed strong population structure within poodles, with differences among some poodle groups as pronounced as those among other well-recognized breeds. Pedigree analysis going three generations back in time confirmed that subgroups within poodles result from assortative mating imposed by breed standards as well as breeder preferences. Matings have not taken place at random or within traditionally identified size classes in poodles. Instead, a novel set of five poodle groups was identified, defined by combinations of size and color, which is not officially recognized by the kennel clubs. Patterns of genetic diversity in other breeds suggest that assortative mating leading to fragmentation may be a common feature within many dog breeds. The genetic structure observed in poodles is the result of local mating patterns, implying that breed fragmentation may be different in different countries. Such pronounced structuring within dog breeds can increase the power of association mapping studies, but also represents a serious problem if ignored. In dog breeding, individuals are selected on the basis of morphology, behaviour, working or show purposes, as well as geographic population structure. The same processes which have historically created dog breeds are still ongoing, and create further subdivision within current dog breeds.

Assortative mating and fragmentation within dog breeds

PubMed Central

2008-01-01

Background There are around 400 internationally recognized dog breeds in the world today, with a remarkable diversity in size, shape, color and behavior. Breeds are considered to be uniform groups with similar physical characteristics, shaped by selection rooted in human preferences. This has led to a large genetic difference between breeds and a large extent of linkage disequilibrium within breeds. These characteristics are important for association mapping of candidate genes for diseases and therefore make dogs ideal models for gene mapping of human disorders. However, genetic uniformity within breeds may not always be the case. We studied patterns of genetic diversity within 164 poodles and compared it to 133 dogs from eight other breeds. Results Our analyses revealed strong population structure within poodles, with differences among some poodle groups as pronounced as those among other well-recognized breeds. Pedigree analysis going three generations back in time confirmed that subgroups within poodles result from assortative mating imposed by breed standards as well as breeder preferences. Matings have not taken place at random or within traditionally identified size classes in poodles. Instead, a novel set of five poodle groups was identified, defined by combinations of size and color, which is not officially recognized by the kennel clubs. Patterns of genetic diversity in other breeds suggest that assortative mating leading to fragmentation may be a common feature within many dog breeds. Conclusion The genetic structure observed in poodles is the result of local mating patterns, implying that breed fragmentation may be different in different countries. Such pronounced structuring within dog breeds can increase the power of association mapping studies, but also represents a serious problem if ignored. In dog breeding, individuals are selected on the basis of morphology, behaviour, working or show purposes, as well as geographic population structure. The same processes which have historically created dog breeds are still ongoing, and create further subdivision within current dog breeds. PMID:18226210

Functional connectivity of visual cortex in the blind follows retinotopic organization principles

PubMed Central

Ovadia-Caro, Smadar; Caramazza, Alfonso; Margulies, Daniel S.; Villringer, Arno

2015-01-01

Is visual input during critical periods of development crucial for the emergence of the fundamental topographical mapping of the visual cortex? And would this structure be retained throughout life-long blindness or would it fade as a result of plastic, use-based reorganization? We used functional connectivity magnetic resonance imaging based on intrinsic blood oxygen level-dependent fluctuations to investigate whether significant traces of topographical mapping of the visual scene in the form of retinotopic organization, could be found in congenitally blind adults. A group of 11 fully and congenitally blind subjects and 18 sighted controls were studied. The blind demonstrated an intact functional connectivity network structural organization of the three main retinotopic mapping axes: eccentricity (centre-periphery), laterality (left-right), and elevation (upper-lower) throughout the retinotopic cortex extending to high-level ventral and dorsal streams, including characteristic eccentricity biases in face- and house-selective areas. Functional connectivity-based topographic organization in the visual cortex was indistinguishable from the normally sighted retinotopic functional connectivity structure as indicated by clustering analysis, and was found even in participants who did not have a typical retinal development in utero (microphthalmics). While the internal structural organization of the visual cortex was strikingly similar, the blind exhibited profound differences in functional connectivity to other (non-visual) brain regions as compared to the sighted, which were specific to portions of V1. Central V1 was more connected to language areas but peripheral V1 to spatial attention and control networks. These findings suggest that current accounts of critical periods and experience-dependent development should be revisited even for primary sensory areas, in that the connectivity basis for visual cortex large-scale topographical organization can develop without any visual experience and be retained through life-long experience-dependent plasticity. Furthermore, retinotopic divisions of labour, such as that between the visual cortex regions normally representing the fovea and periphery, also form the basis for topographically-unique plastic changes in the blind. PMID:25869851

Highly Coarse-Grained Representations of Transmembrane Proteins

PubMed Central

2017-01-01

Numerous biomolecules and biomolecular complexes, including transmembrane proteins (TMPs), are symmetric or at least have approximate symmetries. Highly coarse-grained models of such biomolecules, aiming at capturing the essential structural and dynamical properties on resolution levels coarser than the residue scale, must preserve the underlying symmetry. However, making these models obey the correct physics is in general not straightforward, especially at the highly coarse-grained resolution where multiple (∼3–30 in the current study) amino acid residues are represented by a single coarse-grained site. In this paper, we propose a simple and fast method of coarse-graining TMPs obeying this condition. The procedure involves partitioning transmembrane domains into contiguous segments of equal length along the primary sequence. For the coarsest (lowest-resolution) mappings, it turns out to be most important to satisfy the symmetry in a coarse-grained model. As the resolution is increased to capture more detail, however, it becomes gradually more important to match modular repeats in the secondary structure (such as helix-loop repeats) instead. A set of eight TMPs of various complexity, functionality, structural topology, and internal symmetry, representing different classes of TMPs (ion channels, transporters, receptors, adhesion, and invasion proteins), has been examined. The present approach can be generalized to other systems possessing exact or approximate symmetry, allowing for reliable and fast creation of multiscale, highly coarse-grained mappings of large biomolecular assemblies. PMID:28043122

Bifurcation structure of successive torus doubling

NASA Astrophysics Data System (ADS)

Sekikawa, Munehisa; Inaba, Naohiko; Yoshinaga, Tetsuya; Tsubouchi, Takashi

2006-01-01

The authors discuss the “embryology” of successive torus doubling via the bifurcation theory, and assert that the coupled map of a logistic map and a circle map has a structure capable of generating infinite number of torus doublings.

Staufen1 senses overall transcript secondary structure to regulate translation

PubMed Central

Ricci, Emiliano P; Kucukural, Alper; Cenik, Can; Mercier, Blandine C; Singh, Guramrit; Heyer, Erin E; Ashar-Patel, Ami; Peng, Lingtao; Moore, Melissa J

2015-01-01

Human Staufen1 (Stau1) is a double-stranded RNA (dsRNA)-binding protein implicated in multiple post-transcriptional gene-regulatory processes. Here we combined RNA immunoprecipitation in tandem (RIPiT) with RNase footprinting, formaldehyde cross-linking, sonication-mediated RNA fragmentation and deep sequencing to map Staufen1-binding sites transcriptome wide. We find that Stau1 binds complex secondary structures containing multiple short helices, many of which are formed by inverted Alu elements in annotated 3′ untranslated regions (UTRs) or in ‘strongly distal’ 3′ UTRs. Stau1 also interacts with actively translating ribosomes and with mRNA coding sequences (CDSs) and 3′ UTRs in proportion to their GC content and propensity to form internal secondary structure. On mRNAs with high CDS GC content, higher Stau1 levels lead to greater ribosome densities, thus suggesting a general role for Stau1 in modulating translation elongation through structured CDS regions. Our results also indicate that Stau1 regulates translation of transcription-regulatory proteins. PMID:24336223

Structural determinants of arrestin functions.

PubMed

Gurevich, Vsevolod V; Gurevich, Eugenia V

2013-01-01

Arrestins are a small protein family with only four members in mammals. Arrestins demonstrate an amazing versatility, interacting with hundreds of different G protein-coupled receptor (GPCR) subtypes, numerous nonreceptor signaling proteins, and components of the internalization machinery, as well as cytoskeletal elements, including regular microtubules and centrosomes. Here, we focus on the structural determinants that mediate various arrestin functions. The receptor-binding elements in arrestins were mapped fairly comprehensively, which set the stage for the construction of mutants targeting particular GPCRs. The elements engaged by other binding partners are only now being elucidated and in most cases we have more questions than answers. Interestingly, even very limited and imprecise identification of structural requirements for the interaction with very few other proteins has enabled the development of signaling-biased arrestin mutants. More comprehensive understanding of the structural underpinning of different arrestin functions will pave the way for the construction of arrestins that can link the receptor we want to the signaling pathway of our choosing. Copyright © 2013 Elsevier Inc. All rights reserved.

Structural Determinants of Arrestin Functions

PubMed Central

Gurevich, Vsevolod V.; Gurevich, Eugenia V.

2015-01-01

Arrestins are a small protein family with only four members in mammals. Arrestins demonstrate an amazing versatility, interacting with hundreds of different G protein-coupled receptor (GPCR) subtypes, numerous nonreceptor signaling proteins, and components of the internalization machinery, as well as cytoskeletal elements, including regular microtubules and centrosomes. Here, we focus on the structural determinants that mediate various arrestin functions. The receptor-binding elements in arrestins were mapped fairly comprehensively, which set the stage for the construction of mutants targeting particular GPCRs. The elements engaged by other binding partners are only now being elucidated and in most cases we have more questions than answers. Interestingly, even very limited and imprecise identification of structural requirements for the interaction with very few other proteins has enabled the development of signaling-biased arrestin mutants. More comprehensive understanding of the structural underpinning of different arrestin functions will pave the way for the construction of arrestins that can link the receptor we want to the signaling pathway of our choosing. PMID:23764050

ADMAP-2: The next-generation Antarctic magnetic anomaly map

NASA Astrophysics Data System (ADS)

Golynsky, Alexander; Golynsky, Dmitry; Ferraccioli, Fausto; Jordan, Tom; Damaske, Detlef; Blankenship, Don; Holt, Jack; Young, Duncan; Ivanov, Sergey; Kiselev, Alexander; Jokat, Wilfried; Gohl, Karsten; Eagles, Graeme; Bell, Robin; Armadillo, Egidio; Bozzo, Emanuelle; Caneva, Giorgio; Finn, Carol; Forsberg, Rene; Aitken, Alan

2017-04-01

The Antarctic Digital Magnetic Anomaly Project compiled the first international magnetic anomaly map of the Antarctic region south of 60°S (ADMAP-1) some six years after its 1995 launch (Golynsky et al., 2001; Golynsky et al., 2007; von Frese et al., 2007). This magnetic anomaly compilation provided new insights into the structure and evolution of Antarctica, including its Proterozoic-Archaean cratons, Proterozoic-Palaeozoic orogens, Palaeozoic-Cenozoic magmatic arc systems, continental rift systems and rifted margins, large igneous provinces and the surrounding oceanic gateways. The international working group produced the ADMAP-1 database from more than 1.5 million line-kilometres of terrestrial, airborne, marine and satellite magnetic observations collected during the IGY 1957-58 through 1999. Since the publication of the first magnetic anomaly map, the international geomagnetic community has acquired more than 1.9 million line-km of new airborne and marine data. This implies that the amount of magnetic anomaly data over the Antarctic continent has more than doubled. These new data provide important constraints on the geology of the enigmatic Gamburtsev Subglacial Mountains and Prince Charles Mountains, Wilkes Land, Dronning Maud Land, and other largely unexplored Antarctic areas (Ferraccioli et al., 2011, Aitken et al., 2014¸ Mieth & Jokat, 2014, Golynsky et al., 2013). The processing of the recently acquired data involved quality assessments by careful statistical analysis of the crossover errors. All magnetic data used in the ADMAP-2 compilation were delivered as profiles, although several of them were in raw form. Some datasets were decimated or upward continued to altitudes of 4 km or higher with the higher frequency geological signals smoothed out. The line data used for the ADMAP-1 compilation were reprocessed for obvious errors and residual corrugations. The new near-surface magnetic data were corrected for the international geomagnetic reference field and diurnal effects, edited for high-frequency errors, and levelled to minimize line-correlated noise. The magnetic anomaly data collected mainly in the 21-st century clearly cannot be simply stitched together with the previous surveys. Thus, mutual levelling adjustments were required to accommodate overlaps in these surveys. The final compilation merged all the available aeromagnetic and marine grids to create the new composite grid of the Antarctic with minimal mismatch along the boundaries between the datasets. Regional coverage gaps in the composite grid will be filled with anomaly estimates constrained by both the near-surface data and satellite magnetic observations taken mainly from the CHAMP and Swarm missions. Magnetic data compilations are providing tantalizing new views into regional-scale subglacial geology and crustal architecture in interior of East and West Antarctica. The ADMAP-2 map provides a new geophysical foundation to better understand the geological structure and tectonic history of Antarctica and surrounding marine areas. In particular, it will provide improved constraints on the lithospheric transition of Antarctica to its oceanic basins, and thus enable improved interpretation of the geodynamic evolution of the Antarctic lithosphere that was a key component in the assembly and break-up of the Rodinia and Gondwana supercontinents. This work was supported by the Korea Polar Research Institute.

Mapping the Mayo-Portland adaptability inventory to the international classification of functioning, disability and health.

PubMed

Lexell, Jan; Malec, James F; Jacobsson, Lars J

2012-01-01

To examine the contents of the Mayo-Portland Adaptability Inventory (MPAI-4) by mapping it to the International Classification of Functioning, Disability and Health (ICF). Each of the 30 scoreable items in the MPAI-4 was mapped to the most precise ICF categories. All 30 items could be mapped to components and categories in the ICF. A total of 88 meaningful concepts were identified. There were, on average, 2.9 meaningful concepts per item, and 65% of all concepts could be mapped. Items in the Ability and Adjustment subscales mapped to categories in both the Body Functions and Activity/Participation components of the ICF, whereas all except 1 in the Participation subscale were to categories in the Activity/Participation component. The items could also be mapped to 34 (13%) of the 258 Environmental Factors in the ICF. This mapping provides better definition through more concrete examples (as listed in the ICF) of the types of body functions, activities, and participation indicators that are represented by the 30 scoreable MPAI-4 items. This may assist users throughout the world in understanding the intent of each item, and support further development and the possibility to report results in the form of an ICF categorical profile, making it universally interpretable.

International Psychometric Validation of an EORTC Quality of Life Module Measuring Cancer Related Fatigue (EORTC QLQ-FA12).

PubMed

Weis, Joachim; Tomaszewski, Krzysztof A; Hammerlid, Eva; Ignacio Arraras, Juan; Conroy, Thierry; Lanceley, Anne; Schmidt, Heike; Wirtz, Markus; Singer, Susanne; Pinto, Monica; Alm El-Din, Mohamed; Compter, Inge; Holzner, Bernhard; Hofmeister, Dirk; Chie, Wei-Chu; Czeladzki, Marek; Harle, Amelie; Jones, Louise; Ritter, Sabrina; Flechtner, Hans-Henning; Bottomley, Andrew

2017-05-01

The European Organisation for Research and Treatment of Cancer (EORTC) Group has developed a new multidimensional instrument measuring cancer-related fatigue to be used in conjunction with the quality of life core questionnaire (EORTC QLQ-C30). The module EORTC QLQ-FA13 assesses physical, cognitive, and emotional aspects of cancer-related fatigue. The methodology follows the EORTC guidelines for phase IV validation of modules. This paper focuses on the results of the psychometric validation of the factorial structure of the module. For validation and cross-validation confirmatory factor analysis (maximum likelihood estimation), intraclass correlation and Cronbach alpha for internal consistency were employed. The study involved an international multicenter collaboration of 11 European and non-European countries. A total of 946 patients with various tumor diagnoses were enrolled. Based on the confirmatory factor analysis, we could approve the three-dimensional structure of the module. Removing one item and reassigning the factorial mapping of another item resulted in the EORTC QLQ-FA12. For the revised scale, we found evidence supporting good local (indicator reliability ≥ 0.60, factor reliability ≥ 0.82) and global model fit (GFI t1|t2 = 0.965/0.957, CFI t1|t2 = 0.976/0.972, RMSEA t1|t2 = 0.060/0.069) for both measurement points. For each scale, test-retest reliability proved to be very good (intraclass correlation: R t1-t2 = 0.905-0.921) and internal consistency proved to be good to high (Cronbach alpha = .79-.90). Based on the former phase III module, the multidimensional structure was revised as a phase IV module (EORTC FA12) with an improved scale structure. For a comprehensive validation of the EORTC FA12, further aspects of convergent and divergent validity as well as sensitivity to change should be determined. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Multiscale analysis of the fracture pattern in granite, example of Tamariu's granite, Catalunya.

NASA Astrophysics Data System (ADS)

Bertrand, L.; LeGarzic, E.; Géraud, Y.; Diraison, M.

2012-04-01

Crystalline rocks can be the host of important fluid flow and therefore they can provide a good reservoir potential. In this kind of rocks, the matrice porosity is in general low and a large part of the permeability is governed by the fracture pattern. Thus, they are the first interest of studies in order to characterize and model the fluid flows. Actual reservoirs are underground, and the only access to the fracture pattern is with boreholes and seismic lines. Those methods are investigating different scales and dimensions: seismic is in 3D at a global scale whereas boreholes are 1D at a localized scale. To make the link between the different data, it is necessary to study field analogues where such fractured rocks are outcropping. Tamariu's granite, in Catalunya, has recently been studied as a field analogue of a fractured reservoir. The previous studies have lead to define structural blocks at different scales, linked to the regional deformation. This study's aim is to characterize the internal fracturation of a single structural block with a statistical analysis. We used one dimension scan lines at the scale of a block and 2 dimensions mapping at a more precise scale until the grain scale. The data highlighted that the fracture and fault lengths have a power law relation in 8 orders of scales. So this power law is stretching between seismic and borehole scales. Therefore, the data fit with a very good trust in the power law exponent, which is very well defined. The link between the reservoir scale faults and the internal block fracturation has also been defined in term of the structures orientation. Finally, a comparison between the 1D and 2D measurement could be done. The 1D scan lines show correctly the different fractures families but samples incompletely a part the fracture pattern, whereas the 2D maps which show more the global trends of the fractures and could lose some minor trends orientations.

Extracting Leading Nonlinear Modes of Changing Climate From Global SST Time Series

NASA Astrophysics Data System (ADS)

Mukhin, D.; Gavrilov, A.; Loskutov, E. M.; Feigin, A. M.; Kurths, J.

2017-12-01

Data-driven modeling of climate requires adequate principal variables extracted from observed high-dimensional data. For constructing such variables it is needed to find spatial-temporal patterns explaining a substantial part of the variability and comprising all dynamically related time series from the data. The difficulties of this task rise from the nonlinearity and non-stationarity of the climate dynamical system. The nonlinearity leads to insufficiency of linear methods of data decomposition for separating different processes entangled in the observed time series. On the other hand, various forcings, both anthropogenic and natural, make the dynamics non-stationary, and we should be able to describe the response of the system to such forcings in order to separate the modes explaining the internal variability. The method we present is aimed to overcome both these problems. The method is based on the Nonlinear Dynamical Mode (NDM) decomposition [1,2], but takes into account external forcing signals. An each mode depends on hidden, unknown a priori, time series which, together with external forcing time series, are mapped onto data space. Finding both the hidden signals and the mapping allows us to study the evolution of the modes' structure in changing external conditions and to compare the roles of the internal variability and forcing in the observed behavior. The method is used for extracting of the principal modes of SST variability on inter-annual and multidecadal time scales accounting the external forcings such as CO2, variations of the solar activity and volcanic activity. The structure of the revealed teleconnection patterns as well as their forecast under different CO2 emission scenarios are discussed.[1] Mukhin, D., Gavrilov, A., Feigin, A., Loskutov, E., & Kurths, J. (2015). Principal nonlinear dynamical modes of climate variability. Scientific Reports, 5, 15510. [2] Gavrilov, A., Mukhin, D., Loskutov, E., Volodin, E., Feigin, A., & Kurths, J. (2016). Method for reconstructing nonlinear modes with adaptive structure from multidimensional data. Chaos: An Interdisciplinary Journal of Nonlinear Science, 26(12), 123101.

Developing a scientific procedure for community based hazard mapping and risk mitigation

NASA Astrophysics Data System (ADS)

Verrier, M.

2011-12-01

As an international exchange student from the Geological Sciences Department at San Diego State University (SDSU), I joined the KKN-PPM program at Universitas Gadjah Mada (UGM), Yogyakarta, Indonesia, in July 2011 for 12 days (July 4th to July 16th) of its two month duration (July 4th to August 25th). The KKN-PPM group I was attached was designated 154 and was focused in Plosorejo Village, Karanganyar, Kerjo, Central Java, Indonesia. The mission of KKN-PPM 154 was to survey Plosorejo village for existing landslides, to generate a simple hazard susceptibility map that can be understood by local villagers, and then to begin dissemination of that map into the community. To generate our susceptibility map we first conducted a geological survey of the existing landslides in the field study area, with a focus on determining landslide triggers and gauging areas for susceptibility for future landslides. The methods for gauging susceptibility included lithological observation, the presence of linear cracking, visible loss of structural integrity in structures such as villager homes, as well as collaboration with local residents and with the local rescue and response team. There were three color distinctions used in representing susceptibility which were green, where there is no immediate danger of landslide damage; orange, where transportation routes are at risk of being disrupted by landslides; and red, where imminent landslide potential puts a home in direct danger. The landslide inventory and susceptibility data was compiled into digital mediums such as CorelDraw, ArcGIS and Google Earth. Once a technical map was generated, we presented it to the village leadership for confirmation and modification based on their experience. Finally, we began to use the technical susceptibility map to draft evacuation routes and meeting points in the event of landslides, as well as simple susceptibility maps that can be understood and utilized by local villagers. Landslide mitigation projects that are being conducted alongside the community hazard map include marking evacuation routes with painted bamboo signs, creating a meaningful landslide awareness mural, and installing simple early warning systems that detect land movement and alert residents that evacuation routes should be used. KKN-PPM is scheduled to continue until August 25th, 2011. In the future, research will be done into using the model for community based hazard mapping outlined here in the Geological Sciences Department at SDSU to increase georisk awareness and improve mitigation of landslides in local areas of need such as Tijuana, Mexico.

Neuroarchitecture and neuroanatomy of the Drosophila central complex: A GAL4-based dissection of protocerebral bridge neurons and circuits

PubMed Central

Wolff, Tanya; Iyer, Nirmala A; Rubin, Gerald M

2015-01-01

Insects exhibit an elaborate repertoire of behaviors in response to environmental stimuli. The central complex plays a key role in combining various modalities of sensory information with an insect's internal state and past experience to select appropriate responses. Progress has been made in understanding the broad spectrum of outputs from the central complex neuropils and circuits involved in numerous behaviors. Many resident neurons have also been identified. However, the specific roles of these intricate structures and the functional connections between them remain largely obscure. Significant gains rely on obtaining a comprehensive catalog of the neurons and associated GAL4 lines that arborize within these brain regions, and on mapping neuronal pathways connecting these structures. To this end, small populations of neurons in the Drosophila melanogaster central complex were stochastically labeled using the multicolor flip-out technique and a catalog was created of the neurons, their morphologies, trajectories, relative arrangements, and corresponding GAL4 lines. This report focuses on one structure of the central complex, the protocerebral bridge, and identifies just 17 morphologically distinct cell types that arborize in this structure. This work also provides new insights into the anatomical structure of the four components of the central complex and its accessory neuropils. Most strikingly, we found that the protocerebral bridge contains 18 glomeruli, not 16, as previously believed. Revised wiring diagrams that take into account this updated architectural design are presented. This updated map of the Drosophila central complex will facilitate a deeper behavioral and physiological dissection of this sophisticated set of structures. J. Comp. Neurol. 523:997–1037, 2015. © 2014 Wiley Periodicals, Inc. PMID:25380328

Internal structure of the San Jacinto fault zone in the trifurcation area southeast of Anza, California, from data of dense seismic arrays

NASA Astrophysics Data System (ADS)

Qin, L.; Ben-Zion, Y.; Qiu, H.; Share, P.-E.; Ross, Z. E.; Vernon, F. L.

2018-04-01

We image the internal structure of the San Jacinto fault zone (SJFZ) in the trifurcation area southeast of Anza, California, with seismic records from dense linear and rectangular arrays. The examined data include recordings from more than 20 000 local earthquakes and nine teleseismic events. Automatic detection algorithms and visual inspection are used to identify P and S body waves, along with P- and S-types fault zone trapped waves (FZTW). The location at depth of the main branch of the SJFZ, the Clark fault, is identified from systematic waveform changes across lines of sensors within the dense rectangular array. Delay times of P arrivals from teleseismic and local events indicate damage asymmetry across the fault, with higher damage to the NE, producing a local reversal of the velocity contrast in the shallow crust with respect to the large-scale structure. A portion of the damage zone between the main fault and a second mapped surface trace to the NE generates P- and S-types FZTW. Inversions of high-quality S-type FZTW indicate that the most likely parameters of the trapping structure are width of ˜70 m, S-wave velocity reduction of 60 per cent, Q value of 60 and depth of ˜2 km. The local reversal of the shallow velocity contrast across the fault with respect to large-scale structure is consistent with preferred propagation of earthquake ruptures in the area to the NW.

Structures Within the South Polar Cap of Mars from Three-dimensional Radar Imaging

NASA Astrophysics Data System (ADS)

Putzig, N. E.; Foss, F. J., II; Campbell, B. A.; Phillips, R. J.; Smith, I. B.

2016-12-01

We used Shallow Radar (SHARAD) observations on 2093 orbital passes by the Mars Reconnaissance Orbiter over Planum Australe to construct a 3-D data volume encompassing the entirety of the Martian south polar layered deposits (SPLD) and their surroundings. Efforts are underway to apply 3-D migration processing, an imaging process that will correct off-nadir returns (clutter) and properly position internal structures while improving the overall signal-to-noise ratio (SNR). Clutter mitigation and the structural corrections that migration provides have been particularly effective for a 3-D SHARAD volume over Planum Boreum, notably supporting the mapping of a shallow unconformity linked to the most recent retreat of mid-latitude glaciation (Smith et al., 2016, Science 352) and revealing what appear to be impact craters fully buried within the ice (Putzig et al., 2015, AGU Fall Meeting, Abs. P53G-05). In the preliminary Planum Australe volume, many crater-like structures are also present, adding to the evidence from surface age dating that the SPLD may be an order of magnitude or more older that the 4-Ma-old north polar layered deposits. Migration processing will sharpen this view, and the expected improvement in SNR is likely to reveal structures that are missing or very faint in single-orbit 2-D profiles, such as the deeper sequences within the layered deposits that are often obfuscated by shallow or internal scattering. The clarified views of the polar-cap interiors emerging from each SHARAD 3-D volume advance our ability to map out the interior structures and infer the history of their emplacement. A full assessment of likely buried craters may provide a means to date the deposits that is independent of climate models and goes beyond estimating a surface age. Achieving these objectives would be a major advancement toward the overarching goal of linking the geologic history of the polar layered deposits to climate processes and their history. Figure provides a cut-away view into the SHARAD 3-D volume over Planum Australe looking toward 315°E and showing radar return power (blue high, red low). No migration processing has been applied. The circular no-data zone above 87°S is 310 km across and the vertical dimension shows 17 µs of delay time ( 2.5 km).

Radiation Heat Transfer Between Diffuse-Gray Surfaces Using Higher Order Finite Elements

NASA Technical Reports Server (NTRS)

Gould, Dana C.

2000-01-01

This paper presents recent work on developing methods for analyzing radiation heat transfer between diffuse-gray surfaces using p-version finite elements. The work was motivated by a thermal analysis of a High Speed Civil Transport (HSCT) wing structure which showed the importance of radiation heat transfer throughout the structure. The analysis also showed that refining the finite element mesh to accurately capture the temperature distribution on the internal structure led to very large meshes with unacceptably long execution times. Traditional methods for calculating surface-to-surface radiation are based on assumptions that are not appropriate for p-version finite elements. Two methods for determining internal radiation heat transfer are developed for one and two-dimensional p-version finite elements. In the first method, higher-order elements are divided into a number of sub-elements. Traditional methods are used to determine radiation heat flux along each sub-element and then mapped back to the parent element. In the second method, the radiation heat transfer equations are numerically integrated over the higher-order element. Comparisons with analytical solutions show that the integration scheme is generally more accurate than the sub-element method. Comparison to results from traditional finite elements shows that significant reduction in the number of elements in the mesh is possible using higher-order (p-version) finite elements.

Seismic and structural characterization of the fluid bypass system using 3D and partial stack seismic from passive margin: inside the plumbing system.

NASA Astrophysics Data System (ADS)

Iacopini, David; Maestrelli, Daniele; Jihad, Ali; Bond, Clare; Bonini, Marco

2017-04-01

In recent years enormous attention has been paid to the understanding of the process and mechanism controlling the gas seepage and more generally the fluid expulsion affecting the earth system from onshore to offshore environment. This is because of their demonstrated impact to our environment, climate change and during subsea drilling operation. Several example from active and paleo system has been so far characterized and proposed using subsurface exploration, geophysical and geochemical monitoring technology approaches with the aims to explore what trigger and drive the overpressure necessary maintain the fluid/gas/material expulsion and what are the structure that act as a gateway for gaseous fluid and unconsolidated rock. In this contribution we explore a series of fluid escape structure (ranging from seepage pipes to large blowout pipes structure of km length) using 3D and partial stack seismic data from two distinctive passive margin from the north sea (Loyal field, West Shetland) and the Equatorial Brazil (Ceara' Basin). We will focuses on the characterization of the plumbing system internal architecture and, for selected example, exploring the AVO response (using partial stack) of the internal fluid/unconsolidated rock. The detailed seismic mapping and seismic attributes analysis of the conduit system helped us to recover some detail from the signal response of the chimney internal structures. We observed: (1) small to medium seeps and pipes following structural or sedimentary discontinuities (2) large pipes (probably incipient mud volcanoes) and blowup structures propagating upward irrespective of pre-existing fault by hydraulic fracturing and assisted by the buoyancy of a fluidised and mobilised mud-hydrocarbon mixture. The reflector termination observed inside the main conduits, the distribution of stacked bright reflectors and the AVO analysis suggests an evolution of mechanisms (involving mixture of gas, fluid and probably mud) during pipe birth and development, cycling through classical fluid escape pipes evoking non-Darcy flow to Darcy flow exploiting surrounding permeable bodies (during low fluid recharge period). Limit and uncertainty of the seismic data imaging the internal structure are still controlled by illumination factor, the lateral and vertical resolution (Fresnel. Tuning thickness) and scattering/noise effect of seismic wave when they interact with the plumbing system.

Data-driven mapping of hypoxia-related tumor heterogeneity using DCE-MRI and OE-MRI.

PubMed

Featherstone, Adam K; O'Connor, James P B; Little, Ross A; Watson, Yvonne; Cheung, Sue; Babur, Muhammad; Williams, Kaye J; Matthews, Julian C; Parker, Geoff J M

2018-04-01

Previous work has shown that combining dynamic contrast-enhanced (DCE)-MRI and oxygen-enhanced (OE)-MRI binary enhancement maps can identify tumor hypoxia. The current work proposes a novel, data-driven method for mapping tissue oxygenation and perfusion heterogeneity, based on clustering DCE/OE-MRI data. DCE-MRI and OE-MRI were performed on nine U87 (glioblastoma) and seven Calu6 (non-small cell lung cancer) murine xenograft tumors. Area under the curve and principal component analysis features were calculated and clustered separately using Gaussian mixture modelling. Evaluation metrics were calculated to determine the optimum feature set and cluster number. Outputs were quantitatively compared with a previous non data-driven approach. The optimum method located six robustly identifiable clusters in the data, yielding tumor region maps with spatially contiguous regions in a rim-core structure, suggesting a biological basis. Mean within-cluster enhancement curves showed physiologically distinct, intuitive kinetics of enhancement. Regions of DCE/OE-MRI enhancement mismatch were located, and voxel categorization agreed well with the previous non data-driven approach (Cohen's kappa = 0.61, proportional agreement = 0.75). The proposed method locates similar regions to the previous published method of binarization of DCE/OE-MRI enhancement, but renders a finer segmentation of intra-tumoral oxygenation and perfusion. This could aid in understanding the tumor microenvironment and its heterogeneity. Magn Reson Med 79:2236-2245, 2018. © 2017 The Authors Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. © 2017 The Authors Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine.

Remote sensing strategies for global resource exploration and environmental management

NASA Astrophysics Data System (ADS)

Henderson, Frederick B.

Since 1972, satellite remote sensing, when integrated with other exploration techniques, has demonstrated operational exploration and engineering cost savings and reduced exploration risks through improved geological mapping. Land and ocean remote sensing satellite systems under development for the 1990's by the United States, France, Japan, Canada, ESA, Russia, China, and others, will significantly increase our ability to explore for, develop, and manage energy and mineral resources worldwide. A major difference between these systems is the "Open Skies" and "Non-Discriminatory Access to Data" policies as have been practiced by the U.S. and France and the restrictive nationalistic data policies as have been practiced by Russia and India. Global exploration will use satellite remote sensing to better map regional structural and basin-like features that control the distribution of energy and mineral resources. Improved sensors will better map lithologic and stratigraphic units and identify alteration effects in rocks, soils, and vegetation cover indicative of undiscovered subsurface resources. These same sensors will also map and monitor resource development. The use of satellite remote sensing data will grow substantially through increasing integration with other geophysical, geochemical, and geologic data using improved geographic information systems (GIS). International exploration will focus on underdeveloped countries rather than on mature exploration areas such as the United States, Europe, and Japan. Energy and mineral companies and government agencies in these countries and others will utilize available remote sensing data to acquire economic intelligence on global resources. If the "Non-Discriminatory Access to Data" principle is observed by satellite producing countries, exploration will remain competitive "on the ground". In this manner, remote sensing technology will continue to be developed to better explore for and manage the world's needed resources. If, however, satellite producing countries follow the Russian and Indian lead and restrict civil satellite data as tools of their national security and economic policies, remote sensing technology may become internationally competitive in space, redundant, prohibitively expensive, and generally unavailable to the world community.

Combining 3D structure of real video and synthetic objects

NASA Astrophysics Data System (ADS)

Kim, Man-Bae; Song, Mun-Sup; Kim, Do-Kyoon

1998-04-01

This paper presents a new approach of combining real video and synthetic objects. The purpose of this work is to use the proposed technology in the fields of advanced animation, virtual reality, games, and so forth. Computer graphics has been used in the fields previously mentioned. Recently, some applications have added real video to graphic scenes for the purpose of augmenting the realism that the computer graphics lacks in. This approach called augmented or mixed reality can produce more realistic environment that the entire use of computer graphics. Our approach differs from the virtual reality and augmented reality in the manner that computer- generated graphic objects are combined to 3D structure extracted from monocular image sequences. The extraction of the 3D structure requires the estimation of 3D depth followed by the construction of a height map. Graphic objects are then combined to the height map. The realization of our proposed approach is carried out in the following steps: (1) We derive 3D structure from test image sequences. The extraction of the 3D structure requires the estimation of depth and the construction of a height map. Due to the contents of the test sequence, the height map represents the 3D structure. (2) The height map is modeled by Delaunay triangulation or Bezier surface and each planar surface is texture-mapped. (3) Finally, graphic objects are combined to the height map. Because 3D structure of the height map is already known, Step (3) is easily manipulated. Following this procedure, we produced an animation video demonstrating the combination of the 3D structure and graphic models. Users can navigate the realistic 3D world whose associated image is rendered on the display monitor.

Low Cost and Efficient 3d Indoor Mapping Using Multiple Consumer Rgb-D Cameras

NASA Astrophysics Data System (ADS)

Chen, C.; Yang, B. S.; Song, S.

2016-06-01

Driven by the miniaturization, lightweight of positioning and remote sensing sensors as well as the urgent needs for fusing indoor and outdoor maps for next generation navigation, 3D indoor mapping from mobile scanning is a hot research and application topic. The point clouds with auxiliary data such as colour, infrared images derived from 3D indoor mobile mapping suite can be used in a variety of novel applications, including indoor scene visualization, automated floorplan generation, gaming, reverse engineering, navigation, simulation and etc. State-of-the-art 3D indoor mapping systems equipped with multiple laser scanners product accurate point clouds of building interiors containing billions of points. However, these laser scanner based systems are mostly expensive and not portable. Low cost consumer RGB-D Cameras provides an alternative way to solve the core challenge of indoor mapping that is capturing detailed underlying geometry of the building interiors. Nevertheless, RGB-D Cameras have a very limited field of view resulting in low efficiency in the data collecting stage and incomplete dataset that missing major building structures (e.g. ceilings, walls). Endeavour to collect a complete scene without data blanks using single RGB-D Camera is not technic sound because of the large amount of human labour and position parameters need to be solved. To find an efficient and low cost way to solve the 3D indoor mapping, in this paper, we present an indoor mapping suite prototype that is built upon a novel calibration method which calibrates internal parameters and external parameters of multiple RGB-D Cameras. Three Kinect sensors are mounted on a rig with different view direction to form a large field of view. The calibration procedure is three folds: 1, the internal parameters of the colour and infrared camera inside each Kinect are calibrated using a chess board pattern, respectively; 2, the external parameters between the colour and infrared camera inside each Kinect are calibrated using a chess board pattern; 3, the external parameters between every Kinect are firstly calculated using a pre-set calibration field and further refined by an iterative closet point algorithm. Experiments are carried out to validate the proposed method upon RGB-D datasets collected by the indoor mapping suite prototype. The effectiveness and accuracy of the proposed method is evaluated by comparing the point clouds derived from the prototype with ground truth data collected by commercial terrestrial laser scanner at ultra-high density. The overall analysis of the results shows that the proposed method achieves seamless integration of multiple point clouds form different RGB-D cameras collected at 30 frame per second.

High resolution Ceres HAMO atlas derived from Dawn FC images

NASA Astrophysics Data System (ADS)

Roatsch, Thomas; Kersten, Elke; Matz, Klaus-Dieter; Preusker, Frank; Scholten, Frank; Jaumann, Ralf; Raymond, Carol A.; Russell, Chris T.

2016-04-01

Introduction: NASA's Dawn spacecraft entered the orbit of dwarf planet Ceres in March 2015, and will characterize the geology, elemental and mineralogical composition, topography, shape, and internal structure of Ceres. One of the major goals of the mission is a global mapping of Ceres. Data: The Dawn mission was mapping Ceres in HAMO (High Altitude Mapping Orbit, 1475 km altitude) between August and October 2015. The framing camera took about 2,600 clear filter images with a resolution of about 140 m/pixel during these cycles. The images were taken with different viewing angles and different illumination conditions. We selected images from one cycle (cycle #1) for the mosaicking process to have similar viewing and illumination conditions. Very minor gaps in the coverage were filled with a few images from cycle #2. Data Processing: The first step of the processing chain towards the cartographic products is to ortho-rectify the images to the proper scale and map projec-tion type. This process requires detailed information of the Dawn orbit and attitude data and of the topography of the targets. Both, improved orientation and a high-resolution shape model, are provided by stereo processing (bundle block adjustment) of the HAMO stereo image dataset [3]. Ceres's HAMO shape model was used for the calculation of the ray intersection points while the map projection itself was done onto the reference sphere of Ceres with a radius of 470 km. The final step is the controlled mosaicking) of all images to a global mosaic of Ceres, the so-called basemap. Ceres map tiles: The Ceres atlas was produced in a scale of 1:750,000 and consists of 15 tiles that conform to the quadrangle scheme proposed by Greeley and Batson [4]. A map scale of 1:750,000 guarantees a mapping at the highest available Dawn resolution in HAMO. The individual tiles were extracted from the global mosaic and reprojected. Nomenclature: The Dawn team proposed 81 names for geological features. By international agreement, craters must be named after gods and goddesses of agriculture and vegetation from world mythology, whereas other geological features must be named after agricultural festivals of the world. The nomenclature proposed by the Dawn team was approved by the IAU [http://planetarynames.wr.usgs.gov/] and is shown in Fig. 1. The entire Ceres HAMO atlas will be available to the public through the Dawn GIS web page [http://dawngis.dlr.de/atlas]. References: [1] Russell, C.T. and Raymond, C.A., Space Sci. Rev., 163, DOI 10.1007/s11214-011-9836-2; [2] Sierks, et al., 2011, Space Sci. Rev., 163, DOI 10.1007/s11214-011-9745-4; [3] Preusker, F. et al., this session; [4] Greeley, R. and Batson, G., 1990, Planetary Mapping, Cambridge University Press.

A reference genetic map of C. clementina hort. ex Tan.; citrus evolution inferences from comparative mapping

PubMed Central

2012-01-01

Background Most modern citrus cultivars have an interspecific origin. As a foundational step towards deciphering the interspecific genome structures, a reference whole genome sequence was produced by the International Citrus Genome Consortium from a haploid derived from Clementine mandarin. The availability of a saturated genetic map of Clementine was identified as an essential prerequisite to assist the whole genome sequence assembly. Clementine is believed to be a ‘Mediterranean’ mandarin × sweet orange hybrid, and sweet orange likely arose from interspecific hybridizations between mandarin and pummelo gene pools. The primary goals of the present study were to establish a Clementine reference map using codominant markers, and to perform comparative mapping of pummelo, sweet orange, and Clementine. Results Five parental genetic maps were established from three segregating populations, which were genotyped with Single Nucleotide Polymorphism (SNP), Simple Sequence Repeats (SSR) and Insertion-Deletion (Indel) markers. An initial medium density reference map (961 markers for 1084.1 cM) of the Clementine was established by combining male and female Clementine segregation data. This Clementine map was compared with two pummelo maps and a sweet orange map. The linear order of markers was highly conserved in the different species. However, significant differences in map size were observed, which suggests a variation in the recombination rates. Skewed segregations were much higher in the male than female Clementine mapping data. The mapping data confirmed that Clementine arose from hybridization between ‘Mediterranean’ mandarin and sweet orange. The results identified nine recombination break points for the sweet orange gamete that contributed to the Clementine genome. Conclusions A reference genetic map of citrus, used to facilitate the chromosome assembly of the first citrus reference genome sequence, was established. The high conservation of marker order observed at the interspecific level should allow reasonable inferences of most citrus genome sequences by mapping next-generation sequencing (NGS) data in the reference genome sequence. The genome of the haploid Clementine used to establish the citrus reference genome sequence appears to have been inherited primarily from the ‘Mediterranean’ mandarin. The high frequency of skewed allelic segregations in the male Clementine data underline the probable extent of deviation from Mendelian segregation for characters controlled by heterozygous loci in male parents. PMID:23126659

A Perfect View of Vesta: Creating Pointing Observations for the Dawn Spacecraft on Asteroid 4 Vesta

NASA Technical Reports Server (NTRS)

Hay, Katrina M.

2005-01-01

The Dawn spacecraft has a timely and clever assignment in store. It will take a close look at two intact survivors from the dawn of the solar system (asteroids 4 Vesta and 1 Ceres) to understand more about solar system origin and evolution. To optimize science return, Dawn must make carefully designed observations on approach and in survey orbit, high altitude mapping orbit, and low altitude mapping orbit at each body. In this report, observations outlined in the science plan are modeled using the science opportunity analyzer program for the Vesta encounter. Specifically, I encoded Dawn's flight rules into the program, modeled pointing profiles of the optical instruments (framing camera, visible infrared spectrometer) and mapped their fields of view onto Vesta's surface. Visualization of coverage will provide the science team with information necessary to assess feasibility of alternative observation plans. Dawn launches in summer 2006 and ends its journey in 2016. Instrument observations on Vesta in 2011 will supply detailed information about Vesta's surface and internal structure. These data will be used to analyze the formation and history of the protoplanet and, therefore, complete an important step in understanding the development of our solar system.

International Federation of Library Associations Annual Conference. Papers of the Special Libraries Division: Geographical and Map, Science and Technology and Social Science Libraries Sections (47th, Leipzig, East Germany, August 17-22, 1981).

ERIC Educational Resources Information Center

Sprudzs, Adolf; And Others

This set of eight papers includes papers presented by participants from the United States, France, East Germany, the United Kingdom, West Germany, and the USSR: "Problems with Sources of Information in International Law and Relations: The Case of the World-Wide Treaty Jungle," by Adolf Sprudzs; "French Map Libraries and National and…

Longitudinal structure of the equatorial ionosphere: Time evolution of the four-peaked EIA structure

NASA Astrophysics Data System (ADS)

Lin, C. H.; Hsiao, C. C.; Liu, J. Y.; Liu, C. H.

2007-12-01

Longitudinal structure of the equatorial ionosphere during the 24 h local time period is observed by the FORMOSAT-3/COSMIC (F3/C) satellite constellation. By binning the F3/C radio occultation observations during September and October 2006, global ionospheric total electron content (TEC) maps at a constant local time map (local time TEC map, referred as LT map) can be obtained to monitor the development and subsidence of the four-peaked longitudinal structure of the equatorial ionosphere. From LT maps, the four-peaked structure starts to develop at 0800-1000 LT and becomes most prominent at 1200-1600 LT. The longitudinal structure starts to subside after 2200-2400 LT and becomes indiscernible after 0400-0600 LT. In addition to TEC, ionospheric peak altitude also shows a four-peaked longitudinal structure with variation very similar to TEC during daytime. The four-peaked structure of the ionospheric peak altitude is indiscernible at night. With global local time maps of ionospheric TEC and peak altitude, we compare temporal variations of the longitudinal structure with variations of E × B drift from the empirical model. Our results indicate that the observations are consistent with the hypothesis that the four-peaked longitudinal structure is caused by the equatorial plasma fountain modulated by the E3 nonmigrating tide. Additionally, the four maximum regions show a tendency of moving eastward with propagation velocity of several 10 s m/s.

Lymphatic drainage in renal cell carcinoma: back to the basics.

PubMed

Karmali, Riaz J; Suami, Hiroo; Wood, Christopher G; Karam, Jose A

2014-12-01

Lymphatic drainage in renal cell carcinoma (RCC) is unpredictable, however, basic patterns can be observed in cadaveric and sentinel lymph node mapping studies in patients with RCC. The existence of peripheral lymphovenous communications at the level of the renal vein has been shown in mammals but remains unknown in humans. The sentinel lymph node biopsy technique can be safely applied to map lymphatic drainage patterns in patients with RCC. Further standardisation of sentinel node biopsy techniques is required to improve the clinical significance of mapping studies. Understanding lymphatic drainage in RCC may lead to an evidence-based consensus on the surgical management of retroperitoneal lymph nodes. © 2014 The Authors. BJU International © 2014 BJU International.

NREL: International Activities - Bhutan Resource Maps

Science.gov Websites

modeling approach along with NREL's empirical validation methodology. The high-resolution (10-km) annual -time specific solar mapping approach developed at the U.S. State University of New York at Albany. Data

GIO-EMS and International Collaboration in Satellite based Emergency Mapping

NASA Astrophysics Data System (ADS)

Kucera, Jan; Lemoine, Guido; Broglia, Marco

2013-04-01

During the last decade, satellite based emergency mapping has developed into a mature operational stage. The European Union's GMES Initial Operations - Emergency Management Service (GIO-EMS), is operational since April 2012. It's set up differs from other mechanisms (for example from the International Charter "Space and Major Disasters"), as it extends fast satellite tasking and delivery with the value adding map production as a single service, which is available, free of charge, to the authorized users of the service. Maps and vector datasets with standard characteristics and formats ranging from post-disaster damage assessment to recovery and disaster prevention are covered by this initiative. Main users of the service are European civil protection authorities and international organizations active in humanitarian aid. All non-sensitive outputs of the service are accessible to the public. The European Commission's in-house science service Joint Research Centre (JRC) is the technical and administrative supervisor of the GIO-EMS. The EC's DG ECHO Monitoring and Information Centre acts as the service's focal point and DG ENTR is responsible for overall service governance. GIO-EMS also aims to contribute to the synergy with similar existing mechanisms at national and international level. The usage of satellite data for emergency mapping has increased during the last years and this trend is expected to continue because of easier accessibility to suitable satellite and other relevant data in the near future. Furthermore, the data and analyses coming from volunteer emergency mapping communities are expected to further enrich the content of such cartographic products. In the case of major disasters the parallel activity of more providers is likely to generate non-optimal use of resources, e.g. unnecessary duplication; whereas coordination may lead to reduced time needed to cover the disaster area. Furthermore the abundant number of geospatial products of different characteristics and quality can become confusing for users. The urgent need for a better coordination has led to establishment of the International Working Group on Satellite Based Emergency Mapping (IWG-SEM). Members of the IWG-SEM, which include JRC, USGS, DLR-ZKI, SERVIR, Sentinel Asia, UNOSAT, UN-SPIDER, GEO, ITHACA and SERTIT have recognized the need to establish the best practice between operational satellite-based emergency mapping programs. The group intends to: • work with the appropriate organizations on definition of professional standards for emergency mapping, guidelines for product generation and reviewing relevant technical standards and protocols • facilitate communication and collaboration during the major emergencies • stimulate coordination of expertise and capacities. The existence of the group and the cooperation among members already brought benefits during recent disasters in Africa and Europe in 2012 in terms of faster and effective satellite data provision and better product generation.

Mapping neurotransmitter networks with PET: an example on serotonin and opioid systems.

PubMed

Tuominen, Lauri; Nummenmaa, Lauri; Keltikangas-Järvinen, Liisa; Raitakari, Olli; Hietala, Jarmo

2014-05-01

All functions of the human brain are consequences of altered activity of specific neural pathways and neurotransmitter systems. Although the knowledge of "system level" connectivity in the brain is increasing rapidly, we lack "molecular level" information on brain networks and connectivity patterns. We introduce novel voxel-based positron emission tomography (PET) methods for studying internal neurotransmitter network structure and intercorrelations of different neurotransmitter systems in the human brain. We chose serotonin transporter and μ-opioid receptor for this analysis because of their functional interaction at the cellular level and similar regional distribution in the brain. Twenty-one healthy subjects underwent two consecutive PET scans using [(11)C]MADAM, a serotonin transporter tracer, and [(11)C]carfentanil, a μ-opioid receptor tracer. First, voxel-by-voxel "intracorrelations" (hub and seed analyses) were used to study the internal structure of opioid and serotonin systems. Second, voxel-level opioid-serotonin intercorrelations (between neurotransmitters) were computed. Regional μ-opioid receptor binding potentials were uniformly correlated throughout the brain. However, our analyses revealed nonuniformity in the serotonin transporter intracorrelations and identified a highly connected local network (midbrain-striatum-thalamus-amygdala). Regionally specific intercorrelations between the opioid and serotonin tracers were found in anteromedial thalamus, amygdala, anterior cingulate cortex, dorsolateral prefrontal cortex, and left parietal cortex, i.e., in areas relevant for several neuropsychiatric disorders, especially affective disorders. This methodology enables in vivo mapping of connectivity patterns within and between neurotransmitter systems. Quantification of functional neurotransmitter balances may be a useful approach in etiological studies of neuropsychiatric disorders and also in drug development as a biomarker-based rationale for targeted modulation of neurotransmitter networks. Copyright © 2013 Wiley Periodicals, Inc.

Investigation of dissimilar metal welds by energy-resolved neutron imaging.

PubMed

Tremsin, Anton S; Ganguly, Supriyo; Meco, Sonia M; Pardal, Goncalo R; Shinohara, Takenao; Feller, W Bruce

2016-08-01

A nondestructive study of the internal structure and compositional gradient of dissimilar metal-alloy welds through energy-resolved neutron imaging is described in this paper. The ability of neutrons to penetrate thick metal objects (up to several cm) provides a unique possibility to examine samples which are opaque to other conventional techniques. The presence of Bragg edges in the measured neutron transmission spectra can be used to characterize the internal residual strain within the samples and some microstructural features, e.g. texture within the grains, while neutron resonance absorption provides the possibility to map the degree of uniformity in mixing of the participating alloys and intermetallic formation within the welds. In addition, voids and other defects can be revealed by the variation of neutron attenuation across the samples. This paper demonstrates the potential of neutron energy-resolved imaging to measure all these characteristics simultaneously in a single experiment with sub-mm spatial resolution. Two dissimilar alloy welds are used in this study: Al autogenously laser welded to steel, and Ti gas metal arc welded (GMAW) to stainless steel using Cu as a filler alloy. The cold metal transfer variant of the GMAW process was used in joining the Ti to the stainless steel in order to minimize the heat input. The distributions of the lattice parameter and texture variation in these welds as well as the presence of voids and defects in the melt region are mapped across the welds. The depth of the thermal front in the Al-steel weld is clearly resolved and could be used to optimize the welding process. A highly textured structure is revealed in the Ti to stainless steel joint where copper was used as a filler wire. The limited diffusion of Ti into the weld region is also verified by the resonance absorption.

Communicating infectious disease prevalence through graphics: Results from an international survey.

PubMed

Fagerlin, Angela; Valley, Thomas S; Scherer, Aaron M; Knaus, Megan; Das, Enny; Zikmund-Fisher, Brian J

2017-07-13

Graphics are increasingly used to represent the spread of infectious diseases (e.g., influenza, Zika, Ebola); however, the impact of using graphics to adequately inform the general population is unknown. To examine whether three ways of visually presenting data (heat map, dot map, or picto-trendline)-all depicting the same information regarding the spread of a hypothetical outbreak of influenza-influence intent to vaccinate, risk perception, and knowledge. Survey with participants randomized to receive a simulated news article accompanied by one of the three graphics that communicated prevalence of influenza and number of influenza-related deaths. International online survey. 16,510 adults living in 11 countries selected using stratified random sampling based on age and gender. After reading the article and viewing the presented graphic, participants completed a survey that measured interest in vaccination, perceived risk of contracting disease, knowledge gained, interest in additional information about the disease, and perception of the graphic. Heat maps and picto-trendlines were evaluated more positively than dot maps. Heat maps were more effective than picto-trendlines and no different from dot maps at increasing interest in vaccination, perceived risk of contracting disease, and interest in additional information about the disease. Heat maps and picto-trendlines were more successful at conveying knowledge than dot maps. Overall, heat maps were the only graphic to be superior in every outcome. Results are based on a hypothetical scenario. Heat maps are a viable option to promote interest in and concern about infectious diseases. Published by Elsevier Ltd.

SSMap: a new UniProt-PDB mapping resource for the curation of structural-related information in the UniProt/Swiss-Prot Knowledgebase.

PubMed

David, Fabrice P A; Yip, Yum L

2008-09-23

Sequences and structures provide valuable complementary information on protein features and functions. However, it is not always straightforward for users to gather information concurrently from the sequence and structure levels. The UniProt knowledgebase (UniProtKB) strives to help users on this undertaking by providing complete cross-references to Protein Data Bank (PDB) as well as coherent feature annotation using available structural information. In this study, SSMap - a new UniProt-PDB residue-residue level mapping - was generated. The primary objective of this mapping is not only to facilitate the two tasks mentioned above, but also to palliate a number of shortcomings of existent mappings. SSMap is the first isoform sequence-specific mapping resource and is up-to-date for UniProtKB annotation tasks. The method employed by SSMap differs from the other mapping resources in that it stresses on the correct reconstruction of the PDB sequence from structures, and on the correct attribution of a UniProtKB entry to each PDB chain by using a series of post-processing steps. SSMap was compared to other existing mapping resources in terms of the correctness of the attribution of PDB chains to UniProtKB entries, and of the quality of the pairwise alignments supporting the residue-residue mapping. It was found that SSMap shared about 80% of the mappings with other mapping sources. New and alternative mappings proposed by SSMap were mostly good as assessed by manual verification of data subsets. As for local pairwise alignments, it was shown that major discrepancies (both in terms of alignment lengths and boundaries), when present, were often due to differences in methodologies used for the mappings. SSMap provides an independent, good quality UniProt-PDB mapping. The systematic comparison conducted in this study allows the further identification of general problems in UniProt-PDB mappings so that both the coverage and the quality of the mappings can be systematically improved for the benefit of the scientific community. SSMap mapping is currently used to provide PDB cross-references in UniProtKB.

Differential Globalization of Industry- and Non-Industry-Sponsored Clinical Trials.

PubMed

Atal, Ignacio; Trinquart, Ludovic; Porcher, Raphaël; Ravaud, Philippe

2015-01-01

Mapping the international landscape of clinical trials may inform global health research governance, but no large-scale data are available. Industry or non-industry sponsorship may have a major influence in this mapping. We aimed to map the global landscape of industry- and non-industry-sponsored clinical trials and its evolution over time. We analyzed clinical trials initiated between 2006 and 2013 and registered in the WHO International Clinical Trials Registry Platform (ICTRP). We mapped single-country and international trials by World Bank's income groups and by sponsorship (industry- vs. non- industry), including its evolution over time from 2006 to 2012. We identified clusters of countries that collaborated significantly more than expected in industry- and non-industry-sponsored international trials. 119,679 clinical trials conducted in 177 countries were analysed. The median number of trials per million inhabitants in high-income countries was 100 times that in low-income countries (116.0 vs. 1.1). Industry sponsors were involved in three times more trials per million inhabitants than non-industry sponsors in high-income countries (75.0 vs. 24.5) and in ten times fewer trials in low- income countries (0.08 vs. 1.08). Among industry- and non-industry-sponsored trials, 30.3% and 3.2% were international, respectively. In the industry-sponsored network of collaboration, Eastern European and South American countries collaborated more than expected; in the non-industry-sponsored network, collaboration among Scandinavian countries was overrepresented. Industry-sponsored international trials became more inter-continental with time between 2006 and 2012 (from 54.8% to 67.3%) as compared with non-industry-sponsored trials (from 42.4% to 37.2%). Based on trials registered in the WHO ICTRP we documented a substantial gap between the globalization of industry- and non-industry-sponsored clinical research. Only 3% of academic trials but 30% of industry trials are international. The latter appeared to be conducted in preferentially selected countries.

Differential Globalization of Industry- and Non-Industry–Sponsored Clinical Trials

PubMed Central

Atal, Ignacio; Trinquart, Ludovic; Porcher, Raphaël; Ravaud, Philippe

2015-01-01

Background Mapping the international landscape of clinical trials may inform global health research governance, but no large-scale data are available. Industry or non-industry sponsorship may have a major influence in this mapping. We aimed to map the global landscape of industry- and non-industry–sponsored clinical trials and its evolution over time. Methods We analyzed clinical trials initiated between 2006 and 2013 and registered in the WHO International Clinical Trials Registry Platform (ICTRP). We mapped single-country and international trials by World Bank's income groups and by sponsorship (industry- vs. non- industry), including its evolution over time from 2006 to 2012. We identified clusters of countries that collaborated significantly more than expected in industry- and non-industry–sponsored international trials. Results 119,679 clinical trials conducted in 177 countries were analysed. The median number of trials per million inhabitants in high-income countries was 100 times that in low-income countries (116.0 vs. 1.1). Industry sponsors were involved in three times more trials per million inhabitants than non-industry sponsors in high-income countries (75.0 vs. 24.5) and in ten times fewer trials in low- income countries (0.08 vs. 1.08). Among industry- and non-industry–sponsored trials, 30.3% and 3.2% were international, respectively. In the industry-sponsored network of collaboration, Eastern European and South American countries collaborated more than expected; in the non-industry–sponsored network, collaboration among Scandinavian countries was overrepresented. Industry-sponsored international trials became more inter-continental with time between 2006 and 2012 (from 54.8% to 67.3%) as compared with non-industry–sponsored trials (from 42.4% to 37.2%). Conclusions Based on trials registered in the WHO ICTRP we documented a substantial gap between the globalization of industry- and non-industry–sponsored clinical research. Only 3% of academic trials but 30% of industry trials are international. The latter appeared to be conducted in preferentially selected countries. PMID:26658791

Use of Concept Maps as an Assessment Tool in Mechanical Engineering Education

ERIC Educational Resources Information Center

Tembe, B. L.; Kamble, S. K.

2013-01-01

The purpose of this study to investigate, how third year mechanical engineering students are able to use their knowledge of concept maps in their study of the topic of "Introduction to the Internal Combustion Engines (IICE)". 41 students participated in this study. Firstly, the students were taught about concept maps and then asked to…

Concept Map Engineering: Methods and Tools Based on the Semantic Relation Approach

ERIC Educational Resources Information Center

Kim, Minkyu

2013-01-01

The purpose of this study is to develop a better understanding of technologies that use natural language as the basis for concept map construction. In particular, this study focuses on the semantic relation (SR) approach to drawing rich and authentic concept maps that reflect students' internal representations of a problem situation. The…

Pest risk maps for invasive alien species: a roadmap for improvement

Treesearch

Robert C. Venette; Darren J. Kriticos; Roger D. Magarey; Frank H. Koch; Richard H. A. Baker; Susan P. Worner; Nadila N. Gomez Raboteaux; Daniel W. McKenney; Erhard J. Dobesberger; Denys Yemshanov; Paul J. De Barro; William D. Hutchinson; Glenn Fowler; Tom M. Kalaris; John Pedlar

2010-01-01

Pest risk maps are powerful visual communication tools to describe where invasive alien species might arrive, establish, spread, or cause harmful impacts. These maps inform strategic and tactical pest management decisions, such as potential restrictions on international trade or the design of pest surveys and domestic quarantines. Diverse methods are available to...

Yetter-Drinfeld modules for Hom-bialgebras

DOE Office of Scientific and Technical Information (OSTI.GOV)

Makhlouf, Abdenacer, E-mail: Abdenacer.Makhlouf@uha.fr; Panaite, Florin, E-mail: Florin.Panaite@imar.ro

The aim of this paper is to define and study Yetter-Drinfeld modules over Hom-bialgebras, a generalized version of bialgebras obtained by modifying the algebra and coalgebra structures by a homomorphism. Yetter-Drinfeld modules over a Hom-bialgebra with bijective structure map provide solutions of the Hom-Yang-Baxter equation. The category H/HYD of Yetter-Drinfeld modules with bijective structure maps over a Hom-bialgebra H with bijective structure map can be organized, in two different ways, as a quasi-braided pre-tensor category. If H is quasitriangular (respectively, coquasitriangular) the first (respectively, second) quasi-braided pre-tensor category H/HYD contains, as a quasi-braided pre-tensor subcategory, the category of modules (respectively,more » comodules) with bijective structure maps over H.« less

Geologic map of the Gbanka Quadrangle, Liberia

USGS Publications Warehouse

Force, E.R.; Dunbar, J.D.N.

1974-01-01

As part of a program undertaken cooperatively by the Liberian Geological Survey (LGS) and the U. S. Geological Survey (USGS), under the sponsorship of the Government of Liberia and the Agency for International Development, U. S. Department of State, Liberia was mapped by geologic and geophysical methods during the period 1965 to 1972. The resulting geologic and geophysical maps are published in ten folios, each covering one quadrangle (see index map). 

Towards 3D crystal orientation reconstruction using automated crystal orientation mapping transmission electron microscopy (ACOM-TEM).

PubMed

Kobler, Aaron; Kübel, Christian

2018-01-01

To relate the internal structure of a volume (crystallite and phase boundaries) to properties (electrical, magnetic, mechanical, thermal), a full 3D reconstruction in combination with in situ testing is desirable. In situ testing allows the crystallographic changes in a material to be followed by tracking and comparing the individual crystals and phases. Standard transmission electron microscopy (TEM) delivers a projection image through the 3D volume of an electron-transparent TEM sample lamella. Only with the help of a dedicated TEM tomography sample holder is an accurate 3D reconstruction of the TEM lamella currently possible. 2D crystal orientation mapping has become a standard method for crystal orientation and phase determination while 3D crystal orientation mapping have been reported only a few times. The combination of in situ testing with 3D crystal orientation mapping remains a challenge in terms of stability and accuracy. Here, we outline a method to 3D reconstruct the crystal orientation from a superimposed diffraction pattern of overlapping crystals without sample tilt. Avoiding the typically required tilt series for 3D reconstruction enables not only faster in situ tests but also opens the possibility for more stable and more accurate in situ mechanical testing. The approach laid out here should serve as an inspiration for further research and does not make a claim to be complete.

High-resolution diapycnal mixing map of the Alboran Sea thermocline from seismic reflection images

NASA Astrophysics Data System (ADS)

Mojica, Jhon F.; Sallarès, Valentí; Biescas, Berta

2018-06-01

The Alboran Sea is a dynamically active region where the salty and warm Mediterranean water first encounters the incoming milder and cooler Atlantic water. The interaction between these two water masses originates a set of sub-mesoscale structures and a complex sequence of processes that entail mixing close to the thermocline. Here we present a high-resolution map of the diapycnal diffusivity around the thermocline depth obtained using acoustic data recorded with a high-resolution multichannel seismic system. The map reveals a patchy thermocline, with spots of strong diapycnal mixing juxtaposed with areas of weaker mixing. The patch size is of a few kilometers in the horizontal scale and of 10-15 m in the vertical one. The comparison of the obtained maps with the original acoustic images shows that mixing tends to concentrate in areas where internal waves, which are ubiquitous in the surveyed area, become unstable and shear instabilities develop, enhancing energy transfer towards the turbulent regime. These results are also compared with others obtained using more conventional oceanographic probes. The values estimated based on the seismic data are within the ranges of values obtained from oceanographic data analysis, and they are also consistent with reference theoretical values. Overall, our results demonstrate that high-resolution seismic systems allow the remote quantification of mixing at the thermocline depth with unprecedented resolution.

Modeling adsorption properties of structurally deformed metal–organic frameworks using structure–property map

PubMed Central

Lim, Dae-Woon; Kim, Sungjune; Harale, Aadesh; Yoon, Minyoung; Suh, Myunghyun Paik; Kim, Jihan

2017-01-01

Structural deformation and collapse in metal-organic frameworks (MOFs) can lead to loss of long-range order, making it a challenge to model these amorphous materials using conventional computational methods. In this work, we show that a structure–property map consisting of simulated data for crystalline MOFs can be used to indirectly obtain adsorption properties of structurally deformed MOFs. The structure–property map (with dimensions such as Henry coefficient, heat of adsorption, and pore volume) was constructed using a large data set of over 12000 crystalline MOFs from molecular simulations. By mapping the experimental data points of deformed SNU-200, MOF-5, and Ni-MOF-74 onto this structure–property map, we show that the experimentally deformed MOFs share similar adsorption properties with their nearest neighbor crystalline structures. Once the nearest neighbor crystalline MOFs for a deformed MOF are selected from a structure–property map at a specific condition, then the adsorption properties of these MOFs can be successfully transformed onto the degraded MOFs, leading to a new way to obtain properties of materials whose structural information is lost. PMID:28696307

The Development of Clinical Document Standards for Semantic Interoperability in China

PubMed Central

Yang, Peng; Pan, Feng; Wan, Yi; Tu, Haibo; Tang, Xuejun; Hu, Jianping

2011-01-01

Objectives This study is aimed at developing a set of data groups (DGs) to be employed as reusable building blocks for the construction of the eight most common clinical documents used in China's general hospitals in order to achieve their structural and semantic standardization. Methods The Diagnostics knowledge framework, the related approaches taken from the Health Level Seven (HL7), the Integrating the Healthcare Enterprise (IHE), and the Healthcare Information Technology Standards Panel (HITSP) and 1,487 original clinical records were considered together to form the DG architecture and data sets. The internal structure, content, and semantics of each DG were then defined by mapping each DG data set to a corresponding Clinical Document Architecture data element and matching each DG data set to the metadata in the Chinese National Health Data Dictionary. By using the DGs as reusable building blocks, standardized structures and semantics regarding the clinical documents for semantic interoperability were able to be constructed. Results Altogether, 5 header DGs, 48 section DGs, and 17 entry DGs were developed. Several issues regarding the DGs, including their internal structure, identifiers, data set names, definitions, length and format, data types, and value sets, were further defined. Standardized structures and semantics regarding the eight clinical documents were structured by the DGs. Conclusions This approach of constructing clinical document standards using DGs is a feasible standard-driven solution useful in preparing documents possessing semantic interoperability among the disparate information systems in China. These standards need to be validated and refined through further study. PMID:22259722

Land cover mapping for development planning in Eastern and Southern Africa

NASA Astrophysics Data System (ADS)

Oduor, P.; Flores Cordova, A. I.; Wakhayanga, J. A.; Kiema, J.; Farah, H.; Mugo, R. M.; Wahome, A.; Limaye, A. S.; Irwin, D.

2016-12-01

Africa continues to experience intensification of land use, driven by competition for resources and a growing population. Land cover maps are some of the fundamental datasets required by numerous stakeholders to inform a number of development decisions. For instance, they can be integrated with other datasets to create value added products such as vulnerability impact assessment maps, and natural capital accounting products. In addition, land cover maps are used as inputs into Greenhouse Gas (GHG) inventories to inform the Agriculture, Forestry and other Land Use (AFOLU) sector. However, the processes and methodologies of creating land cover maps consistent with international and national land cover classification schemes can be challenging, especially in developing countries where skills, hardware and software resources can be limiting. To meet this need, SERVIR Eastern and Southern Africa developed methodologies and stakeholder engagement processes that led to a successful initiative in which land cover maps for 9 countries (Malawi, Rwanda, Namibia, Botswana, Lesotho, Ethiopia, Uganda, Zambia and Tanzania) were developed, using 2 major classification schemes. The first sets of maps were developed based on an internationally acceptable classification system, while the second sets of maps were based on a nationally defined classification system. The mapping process benefited from reviews from national experts and also from technical advisory groups. The maps have found diverse uses, among them the definition of the Forest Reference Levels in Zambia. In Ethiopia, the maps have been endorsed by the national mapping agency as part of national data. The data for Rwanda is being used to inform the Natural Capital Accounting process, through the WAVES program, a World Bank Initiative. This work illustrates the methodologies and stakeholder engagement processes that brought success to this land cover mapping initiative.

Translation from the collaborative OSM database to cartography

NASA Astrophysics Data System (ADS)

Hayat, Flora

2018-05-01

The OpenStreetMap (OSM) database includes original items very useful for geographical analysis and for creating thematic maps. Contributors record in the open database various themes regarding amenities, leisure, transports, buildings and boundaries. The Michelin mapping department develops map prototypes to test the feasibility of mapping based on OSM. To translate the OSM database structure into a database structure fitted with Michelin graphic guidelines a research project is in development. It aims at defining the right structure for the Michelin uses. The research project relies on the analysis of semantic and geometric heterogeneities in OSM data. In that order, Michelin implements methods to transform the input geographical database into a cartographic image dedicated for specific uses (routing and tourist maps). The paper focuses on the mapping tools available to produce a personalised spatial database. Based on processed data, paper and Web maps can be displayed. Two prototypes are described in this article: a vector tile web map and a mapping method to produce paper maps on a regional scale. The vector tile mapping method offers an easy navigation within the map and within graphic and thematic guide- lines. Paper maps can be partly automatically drawn. The drawing automation and data management are part of the mapping creation as well as the final hand-drawing phase. Both prototypes have been set up using the OSM technical ecosystem.

The Voronoi spatio-temporal data structure

NASA Astrophysics Data System (ADS)

Mioc, Darka

2002-04-01

Current GIS models cannot integrate the temporal dimension of spatial data easily. Indeed, current GISs do not support incremental (local) addition and deletion of spatial objects, and they can not support the temporal evolution of spatial data. Spatio-temporal facilities would be very useful in many GIS applications: harvesting and forest planning, cadastre, urban and regional planning, and emergency planning. The spatio-temporal model that can overcome these problems is based on a topological model---the Voronoi data structure. Voronoi diagrams are irregular tessellations of space, that adapt to spatial objects and therefore they are a synthesis of raster and vector spatial data models. The main advantage of the Voronoi data structure is its local and sequential map updates, which allows us to automatically record each event and performed map updates within the system. These map updates are executed through map construction commands that are composed of atomic actions (geometric algorithms for addition, deletion, and motion of spatial objects) on the dynamic Voronoi data structure. The formalization of map commands led to the development of a spatial language comprising a set of atomic operations or constructs on spatial primitives (points and lines), powerful enough to define the complex operations. This resulted in a new formal model for spatio-temporal change representation, where each update is uniquely characterized by the numbers of newly created and inactivated Voronoi regions. This is used for the extension of the model towards the hierarchical Voronoi data structure. In this model, spatio-temporal changes induced by map updates are preserved in a hierarchical data structure that combines events and corresponding changes in topology. This hierarchical Voronoi data structure has an implicit time ordering of events visible through changes in topology, and it is equivalent to an event structure that can support temporal data without precise temporal information. This formal model of spatio-temporal change representation is currently applied to retroactive map updates and visualization of map evolution. It offers new possibilities in the domains of temporal GIS, transaction processing, spatio-temporal queries, spatio-temporal analysis, map animation and map visualization.

Understanding National Models for Climate Assessments

NASA Astrophysics Data System (ADS)

Dave, A.; Weingartner, K.

2017-12-01

National-level climate assessments have been produced or are underway in a number of countries. These efforts showcase a variety of approaches to mapping climate impacts onto human and natural systems, and involve a variety of development processes, organizational structures, and intended purposes. This presentation will provide a comparative overview of national `models' for climate assessments worldwide, drawing from a geographically diverse group of nations with varying capacities to conduct such assessments. Using an illustrative sampling of assessment models, the presentation will highlight the range of assessment mandates and requirements that drive this work, methodologies employed, focal areas, and the degree to which international dimensions are included for each nation's assessment. This not only allows the U.S. National Climate Assessment to be better understood within an international context, but provides the user with an entry point into other national climate assessments around the world, enabling a better understanding of the risks and vulnerabilities societies face.

Mapping forces in a 3D elastic assembly of grains

NASA Astrophysics Data System (ADS)

Saadatfar, Mohammad; Sheppard, Adrian P.; Senden, Tim J.; Kabla, Alexandre J.

2012-01-01

Our understanding of the elasticity and rheology of disordered materials, such as granular piles, foams, emulsions or dense suspensions relies on improving experimental tools to characterise their behaviour at the particle scale. While 2D observations are now routinely carried out in laboratories, 3D measurements remain a challenge. In this paper, we use a simple model system, a packing of soft elastic spheres, to illustrate the capability of X-ray microtomography to characterise the internal structure and local behaviour of granular systems. Image analysis techniques can resolve grain positions, shapes and contact areas; this is used to investigate the material's microstructure and its evolution upon strain. In addition to morphological measurements, we develop a technique to quantify contact forces and estimate the internal stress tensor. As will be illustrated in this paper, this opens the door to a broad array of static and dynamical measurements in 3D disordered systems.

MAG3D and its application to internal flowfield analysis

NASA Technical Reports Server (NTRS)

Lee, K. D.; Henderson, T. L.; Choo, Y. K.

1992-01-01

MAG3D (multiblock adaptive grid, 3D) is a 3D solution-adaptive grid generation code which redistributes grid points to improve the accuracy of a flow solution without increasing the number of grid points. The code is applicable to structured grids with a multiblock topology. It is independent of the original grid generator and the flow solver. The code uses the coordinates of an initial grid and the flow solution interpolated onto the new grid. MAG3D uses a numerical mapping and potential theory to modify the grid distribution based on properties of the flow solution on the initial grid. The adaptation technique is discussed, and the capability of MAG3D is demonstrated with several internal flow examples. Advantages of using solution-adaptive grids are also shown by comparing flow solutions on adaptive grids with those on initial grids.

Enlightening intracellular complexity of living cells with quantitative phase microscopy

NASA Astrophysics Data System (ADS)

Martinez Torres, C.; Laperrousaz, B.; Berguiga, L.; Boyer Provera, E.; Elezgaray, J.; Nicolini, F. E.; Maguer-Satta, V.; Arneodo, A.; Argoul, F.

2016-03-01

The internal distribution of refractive indices (RIs) of a living cell is much more complex than usually admitted in multi-shell models. The reconstruction of RI maps from single phase images has rarely been achieved for several reasons: (i) we still have very little knowledge of the impact of internal macromolecular complexes on the local RI and (ii) phase changes produced by light propagation through the sample are mixed with diffraction effects by internal cell bodies. We propose the implementation a 2D wavelet-based contour chain detection method to distinguish internal boundaries thanks to their greatest optical path difference gradients. These contour chains correspond to the highest image phase contrast and follow the local RI inhomogeneities linked to the intracellular structural intricacy. Their statistics and spatial distribution are morphological indicators for distinguishing cells of different origins and to follow their transformation in pathologic situations. We use this method to compare non adherent blood cells from primary and laboratory culture origins, in healthy and pathological situations (chronic myelogenous leukaemia). In a second part of this presentation, we concentrate on the temporal dynamics of the phase contour chains and we discuss the spectral decomposition of their dynamics in both health and disease.

Disentangling interoception: insights from focal strokes affecting the perception of external and internal milieus

PubMed Central

Couto, Blas; Adolfi, Federico; Sedeño, Lucas; Salles, Alejo; Canales-Johnson, Andrés; Alvarez-Abut, Pablo; Garcia-Cordero, Indira; Pietto, Marcos; Bekinschtein, Tristan; Sigman, Mariano; Manes, Facundo; Ibanez, Agustin

2015-01-01

Interoception is the moment-to-moment sensing of the physiological condition of the body. The multimodal sources of interoception can be classified into two different streams of afferents: an internal pathway of signals arising from core structures (i.e., heart, blood vessels, and bronchi) and an external pathway of body-mapped sensations (i.e., chemosensation and pain) arising from peripersonal space. This study examines differential processing along these streams within the insular cortex (IC) and their subcortical tracts connecting frontotemporal networks. Two rare patients presenting focal lesions of the IC (insular lesion, IL) or its subcortical tracts (subcortical lesion, SL) were tested. Internally generated interoceptive streams were assessed through a heartbeat detection (HBD) task, while those externally triggered were tapped via taste, smell, and pain recognition tasks. A differential pattern was observed. The IC patient showed impaired internal signal processing while the SL patient exhibited external perception deficits. Such selective deficits remained even when comparing each patient with a group of healthy controls and a group of brain-damaged patients. These outcomes suggest the existence of distinguishable interoceptive streams. Results are discussed in relation with neuroanatomical substrates, involving a fronto-insulo-temporal network for interoceptive and cognitive contextual integration. PMID:25983697

Brain-mapping projects using the common marmoset.

PubMed

Okano, Hideyuki; Mitra, Partha

2015-04-01

Globally, there is an increasing interest in brain-mapping projects, including the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative project in the USA, the Human Brain Project (HBP) in Europe, and the Brain Mapping by Integrated Neurotechnologies for Disease Studies (Brain/MINDS) project in Japan. These projects aim to map the structure and function of neuronal circuits to ultimately understand the vast complexity of the human brain. Brain/MINDS is focused on structural and functional mapping of the common marmoset (Callithrix jacchus) brain. This non-human primate has numerous advantages for brain mapping, including a well-developed frontal cortex and a compact brain size, as well as the availability of transgenic technologies. In the present review article, we discuss strategies for structural and functional mapping of the marmoset brain and the relation of the common marmoset to other animals models. Copyright © 2014 The Authors. Published by Elsevier Ireland Ltd.. All rights reserved.

New type of chimera and mutual synchronization of spatiotemporal structures in two coupled ensembles of nonlocally interacting chaotic maps

NASA Astrophysics Data System (ADS)

Bukh, Andrei; Rybalova, Elena; Semenova, Nadezhda; Strelkova, Galina; Anishchenko, Vadim

2017-11-01

We study numerically the dynamics of a network made of two coupled one-dimensional ensembles of discrete-time systems. The first ensemble is represented by a ring of nonlocally coupled Henon maps and the second one by a ring of nonlocally coupled Lozi maps. We find that the network of coupled ensembles can realize all the spatio-temporal structures which are observed both in the Henon map ensemble and in the Lozi map ensemble while uncoupled. Moreover, we reveal a new type of spatiotemporal structure, a solitary state chimera, in the considered network. We also establish and describe the effect of mutual synchronization of various complex spatiotemporal patterns in the system of two coupled ensembles of Henon and Lozi maps.

World Digital Magnetic Anomaly Map, development towards the Second Edition. (Invited)

NASA Astrophysics Data System (ADS)

Korhonen, J. V.

2009-12-01

Magnetic anomalies are small deviations in the Earth’s main magnetic field, caused by variation of magnetization in the uppermost lithosphere. Magnetic anomalies provide spatial key information for understanding the structure and evolution of the Earths crust. In practice these anomalies are used e.g. for assessment and prospecting of geological natural resources and planning of land use. A common way to calculate a magnetic anomaly value has been to subtract International Geomagnetic Reference Field (IGRF) from a total field measurement that is cleaned from short term variation of the Earth's magnetic field. World Digital Magnetic Anomaly Map (WDMAM) is a collaborative project between member organizations of International Association of Geomagnetism and Aeronomy (IAGA) and the Commission for Geological Map of the World (CGMW). The First Edition of the map was published in 2007. It consisted of a paper map 1:50 Million and a 3 minutes global grid of total field anomalies at an altitude of 5 km above the geoid. The First Edition was aimed to compile as much as possible available land and sea magnetic data, and homogenize it by comparing anomalies with a satellite magnetic lithospheric field model. This first version was prepared in a tight schedule, to show the usefulness of the map to the community and to form a basis for later development and future editions of the map. Hence, much was left to be improved for the second edition, including sparse coverage in two continents and all southern seas. The satellite models were understood to gain more detail in near future when the CHAMP-satellite would reach lower orbits, and hence higher resolution. The SWARM-satellite constellation was seen to produce even more suitable data in a few years thereafter. Ocean magnetic data sets required careful processing and leveling. The method of homogenization of anomalies included replacing long wavelength information by satellite model spectral data, and hence rejecting corresponding measurements. A challenge was left to include high quality anomaly levels of near ground measurements in global magnetic anomaly grid, where available. For these purposes WDMAM task force calls for both new and improved old data sets, advanced methods for data processing and compilation, and improved anomaly definition schemes. All these would be put together and submitted as candidate grids in 2010, and finally released as WDMAM 2011 (Second Edition) at IUGG 2011, in Australia. All contributions towards this purpose are solicited.

Flow field topology of transient mixing driven by buoyancy

NASA Technical Reports Server (NTRS)

Duval, Walter M B.

2004-01-01

Transient mixing driven by buoyancy occurs through the birth of a symmetric Rayleigh-Taylor morphology (RTM) structure for large length scales. Beyond its critical bifurcation the RTM structure exhibits self-similarity and occurs on smaller and smaller length scales. The dynamics of the RTM structure, its nonlinear growth and internal collision, show that its genesis occurs from an explosive bifurcation which leads to the overlap of resonance regions in phase space. This event shows the coexistence of regular and chaotic regions in phase space which is corroborated with the existence of horseshoe maps. A measure of local chaos given by the topological entropy indicates that as the system evolves there is growth of uncertainty. Breakdown of the dissipative RTM structure occurs during the transition from explosive to catastrophic bifurcation; this event gives rise to annihilation of the separatrices which drives overlap of resonance regions. The global bifurcation of explosive and catastrophic events in phase space for the large length scale of the RTM structure serves as a template for which mixing occurs on smaller and smaller length scales. Copyright 2004 American Institute of Physics.

Mimas: Tectonic structure and geologic history

NASA Technical Reports Server (NTRS)

Croft, Steven K.

1991-01-01

Mimas, the innermost of the major saturnian satellites, occupies an important place in comparative studies of icy satellites. It is the smallest icy satellite known to have a mostly spherical shape. Smaller icy objects like Hyperion and Puck are generally irregular in shape, while larger ones like Miranda and Enceladus are spherical. Thus Mimas is near the diameter where the combination of increasing surface gravity and internal heating begin to have a significant effect on global structure. The nature and extent of endogenic surface features provide important constraints on the interior structure and history of this transitional body. The major landforms on Mimas are impact craters. Mimas has one of the most heavily cratered surfaces in the solar system. The most prominent single feature on Mimas is Herschel, an unrelaxed complex crater 130 km in diameter. The only other recognized landforms on Mimas are tectonic grooves and lineaments. Groove locations were mapped by Schenk, but without analysis of groove structures or superposition relationships. Mimas' tectonic structures are remapped here in more detail than previously has been done, as part of a general study of tectonic features on icy satellites.

A GIS based method for soil mapping in Sardinia, Italy: a geomatic approach.

PubMed

Vacca, A; Loddo, S; Melis, M T; Funedda, A; Puddu, R; Verona, M; Fanni, S; Fantola, F; Madrau, S; Marrone, V A; Serra, G; Tore, C; Manca, D; Pasci, S; Puddu, M R; Schirru, P

2014-06-01

A new project was recently initiated for the realization of the "Land Unit and Soil Capability Map of Sardinia" at a scale of 1:50,000 to support land use planning. In this study, we outline the general structure of the project and the methods used in the activities that have been thus far conducted. A GIS approach was used. We used the soil-landscape paradigm for the prediction of soil classes and their spatial distribution or the prediction of soil properties based on landscape features. The work is divided into two main phases. In the first phase, the available digital data on land cover, geology and topography were processed and classified according to their influence on weathering processes and soil properties. The methods used in the interpretation are based on consolidated and generalized knowledge about the influence of geology, topography and land cover on soil properties. The existing soil data (areal and point data) were collected, reviewed, validated and standardized according to international and national guidelines. Point data considered to be usable were input into a specific database created for the project. Using expert interpretation, all digital data were merged to produce a first draft of the Land Unit Map. During the second phase, this map will be implemented with the existing soil data and verified in the field if also needed with new soil data collection, and the final Land Unit Map will be produced. The Land Unit and Soil Capability Map will be produced by classifying the land units using a reference matching table of land capability classes created for this project. Copyright © 2013 Elsevier Ltd. All rights reserved.

When GIS zooms in: spatio-genetic maps of multipaternity in Armadillidium vulgare.

PubMed

Bech, Nicolas; Depeux, Charlotte; Durand, Sylvine; Debenest, Catherine; Lafitte, Alexandra; Beltran-Bech, Sophie

2017-12-01

Geographic information system (GIS) tools are designed to illustrate, analyse and integrate geographic or spatial data, usually on a macroscopic scale. By contrast, genetic tools focus on a microscopic scale. Because in reality, landscapes have no predefined scale, our original study aims to develop a new approach, combining both cartographic and genetic approaches to explore microscopic landscapes. For this, we focused on Armadillidium vulgare, a terrestrial isopod model in which evolutionary pressures imposed by terrestrial life have led to the development of internal fertilisation and, consequently, to associated physiological changes. Among these, the emergence of internal receptacles, found in many taxa ranging from mammals to arthropods, allowed females to store sperm from several partners, enabling multipaternity. Among arthropods, terrestrial isopods like the polygynandrous A. vulgare present a female structure, the marsupium, in which fertilised eggs migrate and develop into mancae (larval stage). To test our innovative combined approach, we proposed different males to four independent females, and at the end of incubation in the marsupium, we mapped (using GIS methods) and genotyped (using 12 microsatellite markers) all the incubated mancae. This methodology permitted to obtain spatio-genetic maps describing heterozygosity and spatial distribution of mancae and of multipaternity within the marsupial landscape. We discussed the interest of this kind of multidisciplinary approach which could improve in this case our understanding of sexual selection mechanisms in this terrestrial crustacean. Beyond the interesting model-focused insights, the main challenge of this study was the transfer of GIS techniques to a microscopic scale and our results appear so as pioneers rendering GIS tools available for studies involving imagery whatever their study scale.

Functional materials discovery using energy-structure-function maps

NASA Astrophysics Data System (ADS)

Pulido, Angeles; Chen, Linjiang; Kaczorowski, Tomasz; Holden, Daniel; Little, Marc A.; Chong, Samantha Y.; Slater, Benjamin J.; McMahon, David P.; Bonillo, Baltasar; Stackhouse, Chloe J.; Stephenson, Andrew; Kane, Christopher M.; Clowes, Rob; Hasell, Tom; Cooper, Andrew I.; Day, Graeme M.

2017-03-01

Molecular crystals cannot be designed in the same manner as macroscopic objects, because they do not assemble according to simple, intuitive rules. Their structures result from the balance of many weak interactions, rather than from the strong and predictable bonding patterns found in metal-organic frameworks and covalent organic frameworks. Hence, design strategies that assume a topology or other structural blueprint will often fail. Here we combine computational crystal structure prediction and property prediction to build energy-structure-function maps that describe the possible structures and properties that are available to a candidate molecule. Using these maps, we identify a highly porous solid, which has the lowest density reported for a molecular crystal so far. Both the structure of the crystal and its physical properties, such as methane storage capacity and guest-molecule selectivity, are predicted using the molecular structure as the only input. More generally, energy-structure-function maps could be used to guide the experimental discovery of materials with any target function that can be calculated from predicted crystal structures, such as electronic structure or mechanical properties.

Functional materials discovery using energy-structure-function maps.

PubMed

Pulido, Angeles; Chen, Linjiang; Kaczorowski, Tomasz; Holden, Daniel; Little, Marc A; Chong, Samantha Y; Slater, Benjamin J; McMahon, David P; Bonillo, Baltasar; Stackhouse, Chloe J; Stephenson, Andrew; Kane, Christopher M; Clowes, Rob; Hasell, Tom; Cooper, Andrew I; Day, Graeme M

2017-03-30

Molecular crystals cannot be designed in the same manner as macroscopic objects, because they do not assemble according to simple, intuitive rules. Their structures result from the balance of many weak interactions, rather than from the strong and predictable bonding patterns found in metal-organic frameworks and covalent organic frameworks. Hence, design strategies that assume a topology or other structural blueprint will often fail. Here we combine computational crystal structure prediction and property prediction to build energy-structure-function maps that describe the possible structures and properties that are available to a candidate molecule. Using these maps, we identify a highly porous solid, which has the lowest density reported for a molecular crystal so far. Both the structure of the crystal and its physical properties, such as methane storage capacity and guest-molecule selectivity, are predicted using the molecular structure as the only input. More generally, energy-structure-function maps could be used to guide the experimental discovery of materials with any target function that can be calculated from predicted crystal structures, such as electronic structure or mechanical properties.

The sensory equipment of a spider - A morphological survey of different types of sensillum in both sexes of Argiope bruennichi (Araneae, Araneidae).

PubMed

Ganske, Anne-Sarah; Uhl, Gabriele

2018-03-01

Spiders show a wide range of sensory capabilities as evidenced by behavioural observations. Accordingly, spiders possess diverse sensory structures like mechano-, hygro-, thermo- or chemoreceptive sensilla. As to chemoreceptive structures, only trichoid tip-pore sensilla were found so far that were tested for gustation. That spiders are also able to receive airborne signals is corroborated by numerous behavioural experiments but the responsible structures have not been determined yet. Here, we provide sensilla distribution maps of pedipalps and walking legs of both sexes of the wasp spider Argiope bruennichi whose biology and mating system is well explored. By means of scanning electron microscopy, we scrutinized whether there is in fact only one type of trichoid pore sensillum and if so, if there are deviations in the outer structure of the tip-pore sensilla depending on their position on the body. We also describe the external structure and distribution of slit sense organs, trichobothria and tarsal organs. Our study shows that all four sensillum types occur on pedipalps and walking legs of both sexes. As to chemosensory organs, only tip-pore sensilla were found, suggesting that this sensillum type is used for both gustation and olfaction. The highest numbers of tip-pore sensilla were observed on metatarsi and tarsi of the first two walking legs. Mechanosensitive slit sense organs occur as single slit sensilla in rows along all podomers or as lyriform organs next to the joints. The mechanosensitive trichobothria occur on the basal part of tibiae and metatarsi. Tarsal organs occur on the dorsal side of all tarsi and the male cymbium. The distribution maps of the sensilla are the starting point for further exploration of internal, morphological differences of the sensilla from different regions on the body. Cryptic anatomical differences might be linked to functional differences that can be explored in combination with electrophysiological analyses. Consequently, the maps will help to elucidate the sensory world of spiders. Copyright © 2018 Elsevier Ltd. All rights reserved.

Fitting Multimeric Protein Complexes into Electron Microscopy Maps Using 3D Zernike Descriptors

PubMed Central

Esquivel-Rodríguez, Juan; Kihara, Daisuke

2012-01-01

A novel computational method for fitting high-resolution structures of multiple proteins into a cryoelectron microscopy map is presented. The method named EMLZerD generates a pool of candidate multiple protein docking conformations of component proteins, which are later compared with a provided electron microscopy (EM) density map to select the ones that fit well into the EM map. The comparison of docking conformations and the EM map is performed using the 3D Zernike descriptor (3DZD), a mathematical series expansion of three-dimensional functions. The 3DZD provides a unified representation of the surface shape of multimeric protein complex models and EM maps, which allows a convenient, fast quantitative comparison of the three dimensional structural data. Out of 19 multimeric complexes tested, near native complex structures with a root mean square deviation of less than 2.5 Å were obtained for 14 cases while medium range resolution structures with correct topology were computed for the additional 5 cases. PMID:22417139

Fitting multimeric protein complexes into electron microscopy maps using 3D Zernike descriptors.

PubMed

Esquivel-Rodríguez, Juan; Kihara, Daisuke

2012-06-14

A novel computational method for fitting high-resolution structures of multiple proteins into a cryoelectron microscopy map is presented. The method named EMLZerD generates a pool of candidate multiple protein docking conformations of component proteins, which are later compared with a provided electron microscopy (EM) density map to select the ones that fit well into the EM map. The comparison of docking conformations and the EM map is performed using the 3D Zernike descriptor (3DZD), a mathematical series expansion of three-dimensional functions. The 3DZD provides a unified representation of the surface shape of multimeric protein complex models and EM maps, which allows a convenient, fast quantitative comparison of the three-dimensional structural data. Out of 19 multimeric complexes tested, near native complex structures with a root-mean-square deviation of less than 2.5 Å were obtained for 14 cases while medium range resolution structures with correct topology were computed for the additional 5 cases.

Progress in national-scale landslide susceptibility mapping in Romania using a combined statistical-heuristical approach

NASA Astrophysics Data System (ADS)

Bălteanu, Dan; Micu, Mihai; Malet, Jean-Philippe; Jurchescu, Marta; Sima, Mihaela; Kucsicsa, Gheorghe; Dumitrică, Cristina; Petrea, Dănuţ; Mărgărint, Ciprian; Bilaşco, Ştefan; Văcăreanu, Radu; Georgescu, Sever; Senzaconi, Francisc

2017-04-01

Landslide processes represent a very widespread geohazard in Romania, affecting mainly the hilly and plateau regions as well as the mountain sectors developed on flysch formations. Two main projects provided the framework for improving the existing national landslide susceptibility map (Bălteanu et al. 2010): the ELSUS (Pan-European and nation-wide landslide susceptibility assessment, EC-CERG) and the RO-RISK (Disaster Risk Evaluation at National Level, ESF-POCA) projects. The latter one, a flagship project aiming at strengthening risk prevention and management in Romania, focused on a national-level evaluation of the main risks in the country including landslides. The strategy for modeling landslide susceptibility was designed based on the experience gained from continental and national level assessments conducted in the frame of the International Programme on Landslides (IPL) project IPL-162, the European Landslides Expert Group - JRC and the ELSUS project. The newly proposed landslide susceptibility model used as input a reduced set of landslide conditioning factor maps available at scales of 1:100,000 - 1:200,000 and consisting of lithology, slope angle and land cover. The input data was further differentiated for specific natural environments, defined here as morpho-structural units in order to incorporate differences induced by elevation (vertical climatic zonation), morpho-structure as well as neotectonic features. In order to best discern the specific landslide conditioning elements, the analysis has been carried out for one single process category, namely slides. The existence of a landslide inventory covering the whole country's territory ( 30,000 records, Micu et al. 2014), although affected by incompleteness and lack of homogeneity, allowed for the application of a semi-quantitative, mixed statistical-heuristical approach having the advantage of combining the objectivity of statistics with expert-knowledge in calibrating class and factor weights. The maps obtained for the different units were subjected to evaluation and validation using both expert judgment and two additional landslide inventories with national coverage. Expert evaluations were provided for several parts of the country, where possible also using available regional zonations, and derived knowledge was subsequently used for map improvements. The external landslide datasets allowed for validation of the maps through prediction-rate curves (PRC). An improved national landslide susceptibility map of Romania (100 m resolution) resulted from merging the various unit maps and classifying them according to the PRC-thresholds. The final map reveals good performance for most areas. Finally, improvements compared to the previous version of the national map as well as model limitations and possible enhancement requirements are discussed. This study is part of the RO-RISK project (2016) coordinated by the Romanian General Inspectorate for Emergency Situations (IGSU) and supported by the European Social Fund through the Operational Programme for Administrative Capacity (POCA).

Internalization of the human N-formyl peptide and C5a chemoattractant receptors occurs via clathrin-independent mechanisms.

PubMed

Gilbert, T L; Bennett, T A; Maestas, D C; Cimino, D F; Prossnitz, E R

2001-03-27

After stimulation by ligand, most G protein-coupled receptors (GPCRs) undergo rapid phosphorylation, followed by desensitization and internalization. In the case of the N-formyl peptide receptor (FPR), these latter two processing steps have been shown to be entirely dependent on phosphorylation of the receptor's carboxy terminus. We have previously demonstrated that FPR internalization can occur in the absence of receptor desensitization, indicating that FPR desensitization and internalization are regulated differentially. In this study, we have investigated whether human chemoattractant receptors internalize via clathrin-coated pits. Internalization of the FPR transiently expressed in HEK 293 cells was shown to be dependent upon receptor phosphorylation. Despite this, internalization of the FPR, as well as the C5a receptor, was demonstrated to be independent of the actions of arrestin, dynamin, and clathrin. In addition, we utilized fluorescence microscopy to visualize the FPR and beta(2)-adrenergic receptor as they internalized in the same cell, revealing distinct sites of internalization. Last, we found that a nonphosphorylatable mutant of the FPR, unable to internalize, was competent to activate p44/42 MAP kinase. Together, these results demonstrate not only that the FPR internalizes via an arrestin-, dynamin-, and clathrin-independent pathway but also that signal transduction to MAP kinases occurs in an internalization-independent manner.

Intensive Training Course on Microplanning and School Mapping (Arusha, United Republic of Tanzania, March 8-26, 1982). Report.

ERIC Educational Resources Information Center

Caillods, F.; Heyman, S.

This manual contains documentation of a 3-week course conducted jointly in March 1982 by the Tanzanian Ministry of Education and the International Institute for Educational Planning on the subject of the school map (or micro-plan). Prepared at the regional or subregional level, the school map aims at equalizing educational opportunities and…

9. international mouse genome conference

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

This conference was held November 12--16, 1995 in Ann Arbor, Michigan. The purpose of this conference was to provide a multidisciplinary forum for exchange of state-of-the-art information on genetic mapping in mice. This report contains abstracts of presentations, focusing on the following areas: mutation identification; comparative mapping; informatics and complex traits; mutagenesis; gene identification and new technology; and genetic and physical mapping.

Stalking Higher Energy Conformers on the Potential Energy Surface of Charged Species.

PubMed

Brites, Vincent; Cimas, Alvaro; Spezia, Riccardo; Sieffert, Nicolas; Lisy, James M; Gaigeot, Marie-Pierre

2015-03-10

Combined theoretical DFT-MD and RRKM methodologies and experimental spectroscopic infrared predissociation (IRPD) strategies to map potential energy surfaces (PES) of complex ionic clusters are presented, providing lowest and high energy conformers, thresholds to isomerization, and cluster formation pathways. We believe this association not only represents a significant advance in the field of mapping minima and transition states on the PES but also directly measures dynamical pathways for the formation of structural conformers and isomers. Pathways are unraveled over picosecond (DFT-MD) and microsecond (RRKM) time scales while changing the amount of internal energy is experimentally achieved by changing the loss channel for the IRPD measurements, thus directly probing different kinetic and isomerization pathways. Demonstration is provided for Li(+)(H2O)3,4 ionic clusters. Nonstatistical formation of these ionic clusters by both direct and cascade processes, involving isomerization processes that can lead to trapping of high energy conformers along the paths due to evaporative cooling, has been unraveled.

Ultrafast imaging of cell elasticity with optical microelastography

PubMed Central

Grasland-Mongrain, Pol; Zorgani, Ali; Nakagawa, Shoma; Bernard, Simon; Paim, Lia Gomes; Fitzharris, Greg; Catheline, Stefan

2018-01-01

Elasticity is a fundamental cellular property that is related to the anatomy, functionality, and pathological state of cells and tissues. However, current techniques based on cell deformation, atomic force microscopy, or Brillouin scattering are rather slow and do not always accurately represent cell elasticity. Here, we have developed an alternative technique by applying shear wave elastography to the micrometer scale. Elastic waves were mechanically induced in live mammalian oocytes using a vibrating micropipette. These audible frequency waves were observed optically at 200,000 frames per second and tracked with an optical flow algorithm. Whole-cell elasticity was then mapped using an elastography method inspired by the seismology field. Using this approach we show that the elasticity of mouse oocytes is decreased when the oocyte cytoskeleton is disrupted with cytochalasin B. The technique is fast (less than 1 ms for data acquisition), precise (spatial resolution of a few micrometers), able to map internal cell structures, and robust and thus represents a tractable option for interrogating biomechanical properties of diverse cell types. PMID:29339488

KSC-2011-6765

NASA Image and Video Library

2011-09-07

CAPE CANAVERAL, Fla. – – Maria Zuber, GRAIL principal investigator with the Massachusetts Institute of Technology, participates in the Gravity Recovery and Interior Laboratory (GRAIL) mission science briefing in the NASA Press Site auditorium at NASA's Kennedy Space Center in Florida. GRAIL is scheduled to launch Sept. 8 aboard a United Launch Alliance Delta II Heavy rocket from Cape Canaveral Air Force Station in Florida. GRAIL will fly twin spacecraft in tandem around the moon to precisely measure and map variations in the moon's gravitational field. The mission will provide the most accurate global gravity field to date for any planet, including Earth. This detailed information will reveal differences in the density of the moon's crust and mantle and will help answer fundamental questions about the moon's internal structure, thermal evolution, and history of collisions with asteroids. The aim is to map the moon's gravity field so completely that future moon vehicles can safely navigate anywhere on the moon’s surface. For more information, visit http://www.nasa.gov/grail. Photo credit: NASA/Kim Shiflett

Nanoscale mapping of the three-dimensional deformation field within commercial nanodiamonds

DOE PAGES

Maqbool, Muhammad Salman; Hoxley, David; Phillips, Nicholas W.; ...

2017-02-21

Here, the unique properties of nanodiamonds make them suitable for use in a wide range of applications, including as biomarkers for cellular tracking in vivo at the molecular level. The sustained fluorescence of nanodiamonds containing nitrogen-vacancy (N-V) centres is related to their internal structure and strain state. Theoretical studies predict that the location of the N-V centre and the nanodiamonds' residual elastic strain state have a major influence on their photoluminescence properties. However, to date there have been no direct measurements made of their spatially resolved deformation fields owing to the challenges that such measurements present. Here we apply themore » recently developed technique of Bragg coherent diffractive imaging (BCDI) to map the three-dimensional deformation field within a single nanodiamond of approximately 0.5 µm diameter. The results indicate that there are high levels of residual elastic strain present in the nanodiamond which could have a critical influence on its optical and electronic properties.« less

Nanoscale mapping of the three-dimensional deformation field within commercial nanodiamonds

DOE Office of Scientific and Technical Information (OSTI.GOV)

Maqbool, Muhammad Salman; Hoxley, David; Phillips, Nicholas W.

2017-01-01

The unique properties of nanodiamonds make them suitable for use in a wide range of applications, including as biomarkers for cellular tracking in vivo at the molecular level. The sustained fluorescence of nanodiamonds containing nitrogen-vacancy (N-V) centres is related to their internal structure and strain state. Theoretical studies predict that the location of the N-V centre and the nanodiamonds' residual elastic strain state have a major influence on their photoluminescence properties. However, to date there have been no direct measurements made of their spatially resolved deformation fields owing to the challenges that such measurements present. Here we apply the recentlymore » developed technique of Bragg coherent diffractive imaging (BCDI) to map the three-dimensional deformation field within a single nanodiamond of approximately 0.5 µm diameter. The results indicate that there are high levels of residual elastic strain present in the nanodiamond which could have a critical influence on its optical and electronic properties.« less

KSC-2011-6746

NASA Image and Video Library

2011-09-06

CAPE CANAVERAL, Fla. – Tim Dunn, NASA launch director for the agency’s Launch Services Program, participates in the Gravity Recovery and Interior Laboratory (GRAIL) prelaunch news conference in the NASA Press Site auditorium at NASA's Kennedy Space Center in Florida. GRAIL is scheduled to launch Sept. 8 aboard a United Launch Alliance Delta II Heavy rocket from Cape Canaveral Air Force Station in Florida. GRAIL will fly twin spacecraft in tandem around the moon to precisely measure and map variations in the moon's gravitational field. The mission will provide the most accurate global gravity field to date for any planet, including Earth. This detailed information will reveal differences in the density of the moon's crust and mantle and will help answer fundamental questions about the moon's internal structure, thermal evolution, and history of collisions with asteroids. The aim is to map the moon's gravity field so completely that future moon vehicles can safely navigate anywhere on the moon’s surface. For more information, visit http://www.nasa.gov/grail. Photo credit: NASA/Kim Shiflett

KSC-2011-6771

NASA Image and Video Library

2011-09-07

CAPE CANAVERAL, Fla. -- At Space Launch Complex 17B on Cape Canaveral Air Force Station, the United Launch Alliance Delta II rocket that will launch NASA's Gravity Recovery and Interior Laboratory mission is ready for launch. Preparations are under way to roll the mobile service tower away from the rocket. GRAIL will fly twin spacecraft in tandem around the moon to precisely measure and map variations in the moon's gravitational field. The mission will provide the most accurate global gravity field to date for any planet, including Earth. This detailed information will reveal differences in the density of the moon's crust and mantle and will help answer fundamental questions about the moon's internal structure, thermal evolution, and history of collisions with asteroids. The aim is to map the moon's gravity field so completely that future lunar vehicles can safely navigate anywhere on the moon’s surface. Launch is scheduled for 8:37:06 a.m. EDT Sept. 8. For more information, visit http://www.nasa.gov/grail. Photo credit: NASA/Kim Shiflett

KSC-2011-6779

NASA Image and Video Library

2011-09-07

CAPE CANAVERAL, Fla. -- At Space Launch Complex 17B on Cape Canaveral Air Force Station, view of the United Launch Alliance Delta II rocket that will launch NASA's Gravity Recovery and Interior Laboratory mission is unobstructed as the mobile service tower rolls away. The "rollback" began at about 11:20 p.m. EDT. GRAIL will fly twin spacecraft in tandem around the moon to precisely measure and map variations in the moon's gravitational field. The mission will provide the most accurate global gravity field to date for any planet, including Earth. This detailed information will reveal differences in the density of the moon's crust and mantle and will help answer fundamental questions about the moon's internal structure, thermal evolution, and history of collisions with asteroids. The aim is to map the moon's gravity field so completely that future lunar vehicles can safely navigate anywhere on the moon’s surface. Launch is scheduled for 8:37:06 a.m. EDT Sept. 8. For more information, visit http://www.nasa.gov/grail. Photo credit: NASA/Kim Shiflett

KSC-2011-6810

NASA Image and Video Library

2011-09-08

CAPE CANAVERAL, Fla. -- Media representatives check the lighting at Press Site 1 near Space Launch Complex 17B on Cape Canaveral Air Force Station during preparations to photograph the launch of NASA's Gravity Recovery and Interior Laboratory mission. Liftoff aboard a United Launch Alliance Delta II Heavy rocket is scheduled for 8:37:06 a.m. EDT. GRAIL will fly twin spacecraft in tandem around the moon to precisely measure and map variations in the moon's gravitational field. The mission will provide the most accurate global gravity field to date for any planet, including Earth. This detailed information will reveal differences in the density of the moon's crust and mantle and will help answer fundamental questions about the moon's internal structure, thermal evolution, and history of collisions with asteroids. The aim is to map the moon's gravity field so completely that future lunar vehicles can safely navigate anywhere on the moon’s surface. For more information, visit http://www.nasa.gov/grail. Photo credit: NASA/Ken Thornsley

KSC-2011-6750

NASA Image and Video Library

2011-09-06

CAPE CANAVERAL, Fla. – Joel Tumbiolo, launch weather officer, 45th Weather Squadron, Cape Canaveral Air Force Station, Fla., participates in the Gravity Recovery and Interior Laboratory (GRAIL) prelaunch news conference in the NASA Press Site auditorium at NASA's Kennedy Space Center in Florida. GRAIL is scheduled to launch Sept. 8 aboard a United Launch Alliance Delta II Heavy rocket from Cape Canaveral Air Force Station in Florida. GRAIL will fly twin spacecraft in tandem around the moon to precisely measure and map variations in the moon's gravitational field. The mission will provide the most accurate global gravity field to date for any planet, including Earth. This detailed information will reveal differences in the density of the moon's crust and mantle and will help answer fundamental questions about the moon's internal structure, thermal evolution, and history of collisions with asteroids. The aim is to map the moon's gravity field so completely that future moon vehicles can safely navigate anywhere on the moon’s surface. For more information, visit http://www.nasa.gov/grail. Photo credit: NASA/Kim Shiflett

KSC-2011-6748

NASA Image and Video Library

2011-09-06

CAPE CANAVERAL, Fla. – David Lehman, GRAIL project manager, NASA’s Jet Propulsion Laboratory, participates in the Gravity Recovery and Interior Laboratory (GRAIL) prelaunch news conference in the NASA Press Site auditorium at NASA's Kennedy Space Center in Florida. GRAIL is scheduled to launch Sept. 8 aboard a United Launch Alliance Delta II Heavy rocket from Cape Canaveral Air Force Station in Florida. GRAIL will fly twin spacecraft in tandem around the moon to precisely measure and map variations in the moon's gravitational field. The mission will provide the most accurate global gravity field to date for any planet, including Earth. This detailed information will reveal differences in the density of the moon's crust and mantle and will help answer fundamental questions about the moon's internal structure, thermal evolution, and history of collisions with asteroids. The aim is to map the moon's gravity field so completely that future moon vehicles can safely navigate anywhere on the moon’s surface. For more information, visit http://www.nasa.gov/grail. Photo credit: NASA/Kim Shiflett

KSC-2011-6786

NASA Image and Video Library

2011-09-08

CAPE CANAVERAL, Fla. -- At Space Launch Complex 17B on Cape Canaveral Air Force Station, the United Launch Alliance Delta II rocket that will launch NASA's Gravity Recovery and Interior Laboratory mission undergoes final preparations for launch. The "rollback" of the mobile service tower began at about 11:20 p.m. EDT Sept. 7. GRAIL will fly twin spacecraft in tandem around the moon to precisely measure and map variations in the moon's gravitational field. The mission will provide the most accurate global gravity field to date for any planet, including Earth. This detailed information will reveal differences in the density of the moon's crust and mantle and will help answer fundamental questions about the moon's internal structure, thermal evolution, and history of collisions with asteroids. The aim is to map the moon's gravity field so completely that future lunar vehicles can safely navigate anywhere on the moon’s surface. Launch is scheduled for 8:37:06 a.m. EDT Sept. 8. For more information, visit http://www.nasa.gov/grail. Photo credit: NASA/Kim Shiflett

KSC-2011-6764

NASA Image and Video Library

2011-09-07

CAPE CANAVERAL, Fla. – Robert Fogel, NASA’s GRAIL program scientist, participates in the Gravity Recovery and Interior Laboratory (GRAIL) mission science briefing in the NASA Press Site auditorium at NASA's Kennedy Space Center in Florida. GRAIL is scheduled to launch Sept. 8 aboard a United Launch Alliance Delta II Heavy rocket from Cape Canaveral Air Force Station in Florida. GRAIL will fly twin spacecraft in tandem around the moon to precisely measure and map variations in the moon's gravitational field. The mission will provide the most accurate global gravity field to date for any planet, including Earth. This detailed information will reveal differences in the density of the moon's crust and mantle and will help answer fundamental questions about the moon's internal structure, thermal evolution, and history of collisions with asteroids. The aim is to map the moon's gravity field so completely that future moon vehicles can safely navigate anywhere on the moon’s surface. For more information, visit http://www.nasa.gov/grail. Photo credit: NASA/Kim Shiflett

KSC-2011-6751

NASA Image and Video Library

2011-09-06

CAPE CANAVERAL, Fla. – John Henk, GRAIL program manager, Lockheed Martin Space Systems, Denver, Colo., participates in the Gravity Recovery and Interior Laboratory (GRAIL) prelaunch news conference in the NASA Press Site auditorium at NASA's Kennedy Space Center in Florida. GRAIL is scheduled to launch Sept. 8 aboard a United Launch Alliance Delta II Heavy rocket from Cape Canaveral Air Force Station in Florida. GRAIL will fly twin spacecraft in tandem around the moon to precisely measure and map variations in the moon's gravitational field. The mission will provide the most accurate global gravity field to date for any planet, including Earth. This detailed information will reveal differences in the density of the moon's crust and mantle and will help answer fundamental questions about the moon's internal structure, thermal evolution, and history of collisions with asteroids. The aim is to map the moon's gravity field so completely that future moon vehicles can safely navigate anywhere on the moon’s surface. For more information, visit http://www.nasa.gov/grail. Photo credit: NASA/Kim Shiflett

KSC-2011-6770

NASA Image and Video Library

2011-09-07

CAPE CANAVERAL, Fla. -- At Space Launch Complex 17B on Cape Canaveral Air Force Station, preparations are under way to roll the mobile service tower away from the United Launch Alliance Delta II rocket that will launch NASA's Gravity Recovery and Interior Laboratory mission. GRAIL will fly twin spacecraft in tandem around the moon to precisely measure and map variations in the moon's gravitational field. The mission will provide the most accurate global gravity field to date for any planet, including Earth. This detailed information will reveal differences in the density of the moon's crust and mantle and will help answer fundamental questions about the moon's internal structure, thermal evolution, and history of collisions with asteroids. The aim is to map the moon's gravity field so completely that future lunar vehicles can safely navigate anywhere on the moon’s surface. Launch is scheduled for 8:37:06 a.m. EDT Sept. 8. For more information, visit http://www.nasa.gov/grail. Photo credit: NASA/Kim Shiflett

KSC-2011-6878

NASA Image and Video Library

2011-09-10

CAPE CANAVERAL, Fla. – An early morning sky illuminates the United Launch Alliance Delta II Heavy rocket that will launch NASA’s twin Gravity Recovery and Interior Laboratory (GRAIL) mission from Space Launch Complex 17B on Cape Canaveral Air Force Station in Florida. Liftoff is scheduled for 9:08:52 a.m. EDT Sept.10. GRAIL will fly twin spacecraft in tandem around the moon to precisely measure and map variations in the moon's gravitational field. The mission will provide the most accurate global gravity field to date for any planet, including Earth. This detailed information will reveal differences in the density of the moon's crust and mantle and will help answer fundamental questions about the moon's internal structure, thermal evolution, and history of collisions with asteroids. The aim is to map the moon's gravity field so completely that future moon vehicles can safely navigate anywhere on the moon’s surface. For more information, visit http://www.nasa.gov/grail. Photo credit: NASA/ Kim Shiflett

KSC-2011-6749

NASA Image and Video Library

2011-09-06

CAPE CANAVERAL, Fla. – Ed Weiler, NASA associate administrator, Science Mission Directorate, participates in the Gravity Recovery and Interior Laboratory (GRAIL) prelaunch news conference in the NASA Press Site auditorium at NASA's Kennedy Space Center in Florida. GRAIL is scheduled to launch Sept. 8 aboard a United Launch Alliance Delta II Heavy rocket from Cape Canaveral Air Force Station in Florida. GRAIL will fly twin spacecraft in tandem around the moon to precisely measure and map variations in the moon's gravitational field. The mission will provide the most accurate global gravity field to date for any planet, including Earth. This detailed information will reveal differences in the density of the moon's crust and mantle and will help answer fundamental questions about the moon's internal structure, thermal evolution, and history of collisions with asteroids. The aim is to map the moon's gravity field so completely that future moon vehicles can safely navigate anywhere on the moon’s surface. For more information, visit http://www.nasa.gov/grail. Photo credit: NASA/Kim Shiflett

KSC-2011-6875

NASA Image and Video Library

2011-09-10

CAPE CANAVERAL, Fla. – With a clear blue sky for a background, the United Launch Alliance Delta II Heavy rocket is propelled skyward after lifting off at 9:08 a.m. EDT Sept. 10 from Space Launch Complex 17B on Cape Canaveral Air Force Station in Florida. The Delta II is carrying NASA’s twin Gravity Recovery and Interior Laboratory (GRAIL) mission to the moon. GRAIL will fly twin spacecraft in tandem around the moon to precisely measure and map variations in the moon's gravitational field. The mission will provide the most accurate global gravity field to date for any planet, including Earth. This detailed information will reveal differences in the density of the moon's crust and mantle and will help answer fundamental questions about the moon's internal structure, thermal evolution, and history of collisions with asteroids. The aim is to map the moon's gravity field so completely that future moon vehicles can safely navigate anywhere on the moon’s surface. For more information, visit http://www.nasa.gov/grail. Photo credit: NASA/Kim Shiflett

KSC-2011-6809

NASA Image and Video Library

2011-09-08

CAPE CANAVERAL, Fla. -- Television satellite trucks raise their antennas at Press Site 1 near Space Launch Complex 17B on Cape Canaveral Air Force Station during preparations to broadcast the launch of NASA's Gravity Recovery and Interior Laboratory mission. Liftoff aboard a United Launch Alliance Delta II Heavy rocket is scheduled for 8:37:06 a.m. EDT. GRAIL will fly twin spacecraft in tandem around the moon to precisely measure and map variations in the moon's gravitational field. The mission will provide the most accurate global gravity field to date for any planet, including Earth. This detailed information will reveal differences in the density of the moon's crust and mantle and will help answer fundamental questions about the moon's internal structure, thermal evolution, and history of collisions with asteroids. The aim is to map the moon's gravity field so completely that future lunar vehicles can safely navigate anywhere on the moon’s surface. For more information, visit http://www.nasa.gov/grail. Photo credit: NASA/Ken Thornsley

ALOS PALSAR Applications in the Tropics and Subtropics: Characterisation, Mapping and Detecting Change in Forests and Coastal Wetlands

NASA Astrophysics Data System (ADS)

Lucas, Richard; Carreiras, Joao; Proisy, Christophe; Buniting, Peter

2008-11-01

Research undertaken as part of the Japanese Space Exploration Agency (JAXA) Principal Investigator (PI) and Kyoto and Carbon (K&C) programs has focused on the regional characterization (growth stage as a function of biomass and structure) and mapping of forests across northern Australia and mangroves (including wetlands) in selected tropical regions (northern Australia, Belize, French Guiana and Brazil) using Advanced Land Observing Satellite (ALOS) Phased Array L-band SAR (PALSAR) data, either singularly or in conjunction with other remote sensing (e.g., optical) data. Comparison against existing baseline datasets has allowed these data to be used for detecting change in these tropical and subtropical regions. Regional products (e.g., forest growth stage, mangrove/wetland extent and change) generated from the K&C dual polarimetric strip data are anticipated to benefit conservation of these ecosystems and allow better assessments of carbon stocks and changes in these as a function of natural and anthropogenic drivers, thereby supporting key international conventions.

Enabling cost-effective multimodal trip planners through open transit data.

DOT National Transportation Integrated Search

2011-05-01

This study examined whether multimodal trip planners can be developed using opensource software and open data sources. : OpenStreetMap (OSM), maintained by the nonprofit OpenStreetMap Foundation, is an open, freely available international : rep...

Enabling cost-effective multimodal trip planners through open transit data.

DOT National Transportation Integrated Search

2011-05-01

This study examined whether multimodal trip planners can be developed using opensource software and open data sources. OpenStreetMap (OSM), maintained by the nonprofit OpenStreetMap Foundation, is an open, freely available international reposit...

Energy Spectral Behaviors of Communication Networks of Open-Source Communities

PubMed Central

Yang, Jianmei; Yang, Huijie; Liao, Hao; Wang, Jiangtao; Zeng, Jinqun

2015-01-01

Large-scale online collaborative production activities in open-source communities must be accompanied by large-scale communication activities. Nowadays, the production activities of open-source communities, especially their communication activities, have been more and more concerned. Take CodePlex C # community for example, this paper constructs the complex network models of 12 periods of communication structures of the community based on real data; then discusses the basic concepts of quantum mapping of complex networks, and points out that the purpose of the mapping is to study the structures of complex networks according to the idea of quantum mechanism in studying the structures of large molecules; finally, according to this idea, analyzes and compares the fractal features of the spectra in different quantum mappings of the networks, and concludes that there are multiple self-similarity and criticality in the communication structures of the community. In addition, this paper discusses the insights and application conditions of different quantum mappings in revealing the characteristics of the structures. The proposed quantum mapping method can also be applied to the structural studies of other large-scale organizations. PMID:26047331

Floral ontogeny and gene protein localization rules out euanthial interpretation of reproductive units in Lepironia (Cyperaceae, Mapanioideae, Chrysitricheae)

PubMed Central

Prychid, C. J.; Bruhl, J. J.

2013-01-01

Background and Aims In the sedge subfamily Mapanioideae there are considerable discrepancies between the standard trimerous monocot floral architecture expected and the complex floral and inflorescence morphologies seen. Decades of debate about whether the basic reproductive units are single flowers or pseudanthia have not resolved the question. This paper evaluates current knowledge about Mapaniid reproductive structures and presents an ontogenetic study of the Mapaniid genus Lepironia with the first floral protein expression maps for the family, localizing the products of the APETALA1/FRUITFULL-like (AP1/FUL) MADS-box genes with the aim of shedding light on this conundrum. Methods A range of reproductive developmental stages, from spikelet primordia through to infructescence material, were processed for anatomical and immunohistochemical analyses. Key Results The basic reproductive unit is subtended by a bract and possesses two prophyll-like structures, the first organs to be initiated on the primordium, which grow rapidly, enclosing two whorls of initiating leaf-like structures with intervening stamens and a central gynoecium, formed from an annular primordium. The subtending bract and prophyll-like structures possess very different morphologies from that of the internal leaf-like structures and do not show AP1/FUL-like protein localization, which is otherwise strongly localized in the internal leaf-like structures, stamens and gynoecia. Conclusions Results support the synanthial hypothesis as the evolutionary origin of the reproductive unit. Thus, the basic reproductive unit in Lepironia is an extremely condensed pseudanthium, of staminate flowers surrounding a central terminal pistillate female flower. Early in development the reproductive unit becomes enclosed by a split-prophyll, with the whole structure subtended by a bract. PMID:23723258

Middle Atmosphere Cooperation/Summer in Northern Europe (MAC/SINE) and MAC/Epsilon

NASA Technical Reports Server (NTRS)

Thrane, E. V.

1989-01-01

Two major international campaigns dedicated to the study of middle atmosphere dynamics in high latitudes were successfully completed in 1987. MAC/SINE (Middle Atmosphere Cooperation/Summer in Northern Europe) was carried out during the period 7 June to 19 July, whereas MAC/Epsilon took place in the period 12 October to 15 November. In both campaigns a large number of ground based and rocket techniques were used in a concerted effort to map the dynamical structure of the middle atmosphere over Northern Europe. Although the analysis of the observations has only just started, it is clear that a large and unique data set was obtained, which is believed will provide new insight into the dynamical processes in this interesting region of the atmosphere. A brief overview of the campaigns, their scientific aims, organization and structure is presented.

Elastic membranes in confinement.

PubMed

Bostwick, J B; Miksis, M J; Davis, S H

2016-07-01

An elastic membrane stretched between two walls takes a shape defined by its length and the volume of fluid it encloses. Many biological structures, such as cells, mitochondria and coiled DNA, have fine internal structure in which a membrane (or elastic member) is geometrically 'confined' by another object. Here, the two-dimensional shape of an elastic membrane in a 'confining' box is studied by introducing a repulsive confinement pressure that prevents the membrane from intersecting the wall. The stage is set by contrasting confined and unconfined solutions. Continuation methods are then used to compute response diagrams, from which we identify the particular membrane mechanics that generate mitochondria-like shapes. Large confinement pressures yield complex response diagrams with secondary bifurcations and multiple turning points where modal identities may change. Regions in parameter space where such behaviour occurs are then mapped. © 2016 The Author(s).

Internal structure visualization of flow and flame by process tomography and PLIF data fusion

NASA Astrophysics Data System (ADS)

Liu, J.; Liu, Shi; Sun, S.; Pan, X.; Schlaberg, I. H. I.

2018-02-01

To address the increasing demands on pollution control and energy saving, the study of low-emission and high-efficiency burners has been emphasized worldwide. Swirl-induced environmental burners (EV-burners), have notable features aligned with these requirements. In this study, an EV burner is investigated by both an ECT system and an OH-PLIF system. The aim is to detect the structure of a flame and obtain more information about the combustion process in an EV burner. 3D ECT sensitivity maps are generated for the measurement and OH-PLIF images are acquired in the same combustion zone as for the ECT measurements. The experimental images of a flame by ECT are in good agreement with the OH radical distribution pictures captured by OH-PLIF, which provide a mutual verification of the visualization method.

Report of the panel on plate motion and deformation, section 2

NASA Technical Reports Server (NTRS)

Bock, Yehuda; Kastens, Kim A.; Mcnutt, Marcia K.; Minster, J. Bernard; Peltzer, Gilles; Prescott, William H.; Reilinger, Robert E.; Royden, Leigh; Rundle, John B.; Sauber, Jeanne M.

1991-01-01

Given here is a panel report on the goals and objectives, requirements and recommendations for the investigation of plate motion and deformation. The goals are to refine our knowledge of plate motions, study regional and local deformation, and contribute to the solution of important societal problems. The requirements include basic space-positioning measurements, the use of global and regional data sets obtained with space-based techniques, topographic and geoid data to help characterize the internal processes that shape the planet, gravity data to study the density structure at depth and help determine the driving mechanisms for plate tectonics, and satellite images to map lithology, structure and morphology. The most important recommendation of the panel is for the implementation of a world-wide space-geodetic fiducial network to provide a systematic and uniform measure of global strain.

The symmetric quartic map for trajectories of magnetic field lines in elongated divertor tokamak plasmas

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jones, Morgin; Wadi, Hasina; Ali, Halima

The coordinates of the area-preserving map equations for integration of magnetic field line trajectories in divertor tokamaks can be any coordinates for which a transformation to ({psi}{sub t},{theta},{phi}) coordinates exists [A. Punjabi, H. Ali, T. Evans, and A. Boozer, Phys. Lett. A 364, 140 (2007)]. {psi}{sub t} is toroidal magnetic flux, {theta} is poloidal angle, and {phi} is toroidal angle. This freedom is exploited to construct the symmetric quartic map such that the only parameter that determines magnetic geometry is the elongation of the separatrix surface. The poloidal flux inside the separatrix, the safety factor as a function of normalizedmore » minor radius, and the magnetic perturbation from the symplectic discretization are all held constant, and only the elongation is {kappa} varied. The width of stochastic layer, the area, and the fractal dimension of the magnetic footprint and the average radial diffusion coefficient of magnetic field lines from the stochastic layer; and how these quantities scale with {kappa} is calculated. The symmetric quartic map gives the correct scalings which are consistent with the scalings of coordinates with {kappa}. The effects of m=1, n={+-}1 internal perturbation with the amplitude that is expected to occur in tokamaks are calculated by adding a term [H. Ali, A. Punjabi, A. H. Boozer, and T. Evans, Phys. Plasmas 11, 1908 (2004)] to the symmetric quartic map. In this case, the width of stochastic layer scales as 0.35 power of {kappa}. The area of the footprint is roughly constant. The average radial diffusion coefficient of field lines near the X-point scales linearly with {kappa}. The low mn perturbation changes the quasisymmetric structure of the footprint, and reorganizes it into a single, large scale, asymmetric structure. The symmetric quartic map is combined with the dipole map [A. Punjabi, H. Ali, and A. H. Boozer, Phys. Plasmas 10, 3992 (2003)] to calculate the effects of magnetic perturbation from a current carrying coil. The coil position and coil current coil are constant. The dipole perturbation enhances the magnetic shear. The width of the stochastic layer scales exponentially with {kappa}. The area of the footprint decreases as the {kappa} increases. The radial diffusion coefficient of field lines scales exponentially with {kappa}. The dipole perturbation changes the topology of the footprint. It breaks up the toroidally spiraling footprint into a number of separate asymmetric toroidal strips. Practical applications of the symmetric quartic map to elongated divertor tokamak plasmas are suggested.« less

The symmetric quartic map for trajectories of magnetic field lines in elongated divertor tokamak plasmas

NASA Astrophysics Data System (ADS)

Jones, Morgin; Wadi, Hasina; Ali, Halima; Punjabi, Alkesh

2009-04-01

The coordinates of the area-preserving map equations for integration of magnetic field line trajectories in divertor tokamaks can be any coordinates for which a transformation to (ψt,θ,φ) coordinates exists [A. Punjabi, H. Ali, T. Evans, and A. Boozer, Phys. Lett. A 364, 140 (2007)]. ψt is toroidal magnetic flux, θ is poloidal angle, and φ is toroidal angle. This freedom is exploited to construct the symmetric quartic map such that the only parameter that determines magnetic geometry is the elongation of the separatrix surface. The poloidal flux inside the separatrix, the safety factor as a function of normalized minor radius, and the magnetic perturbation from the symplectic discretization are all held constant, and only the elongation is κ varied. The width of stochastic layer, the area, and the fractal dimension of the magnetic footprint and the average radial diffusion coefficient of magnetic field lines from the stochastic layer; and how these quantities scale with κ is calculated. The symmetric quartic map gives the correct scalings which are consistent with the scalings of coordinates with κ. The effects of m =1, n =±1 internal perturbation with the amplitude that is expected to occur in tokamaks are calculated by adding a term [H. Ali, A. Punjabi, A. H. Boozer, and T. Evans, Phys. Plasmas 11, 1908 (2004)] to the symmetric quartic map. In this case, the width of stochastic layer scales as 0.35 power of κ. The area of the footprint is roughly constant. The average radial diffusion coefficient of field lines near the X-point scales linearly with κ. The low mn perturbation changes the quasisymmetric structure of the footprint, and reorganizes it into a single, large scale, asymmetric structure. The symmetric quartic map is combined with the dipole map [A. Punjabi, H. Ali, and A. H. Boozer, Phys. Plasmas 10, 3992 (2003)] to calculate the effects of magnetic perturbation from a current carrying coil. The coil position and coil current coil are constant. The dipole perturbation enhances the magnetic shear. The width of the stochastic layer scales exponentially with κ. The area of the footprint decreases as the κ increases. The radial diffusion coefficient of field lines scales exponentially with κ. The dipole perturbation changes the topology of the footprint. It breaks up the toroidally spiraling footprint into a number of separate asymmetric toroidal strips. Practical applications of the symmetric quartic map to elongated divertor tokamak plasmas are suggested.

Image processing for optical mapping.

PubMed

Ravindran, Prabu; Gupta, Aditya

2015-01-01

Optical Mapping is an established single-molecule, whole-genome analysis system, which has been used to gain a comprehensive understanding of genomic structure and to study structural variation of complex genomes. A critical component of Optical Mapping system is the image processing module, which extracts single molecule restriction maps from image datasets of immobilized, restriction digested and fluorescently stained large DNA molecules. In this review, we describe robust and efficient image processing techniques to process these massive datasets and extract accurate restriction maps in the presence of noise, ambiguity and confounding artifacts. We also highlight a few applications of the Optical Mapping system.

Multilevel Drivers of HIV/AIDS among Black Philadelphians: Exploration Using Community Ethnography and Geographic Information Systems

PubMed Central

Brawner, Bridgette M.; Reason, Janaiya L.; Goodman, Bridget A.; Schensul, Jean J.; Guthrie, Barbara

2014-01-01

Background Unequal HIV/AIDS distribution is influenced by certain social and structural contexts that facilitate HIV transmission and concentrate HIV in disease epicenters. Thus, one of the first steps in designing effective community-level HIV/AIDS initiatives is to disentangle the influence of individual, social, and structural factors on HIV risk. Combining ethnographic methodology with geographic information systems (GIS) mapping can allow for a complex exploration of multilevel factors within communities that facilitate HIV transmission in highly affected areas. Objectives We present the formative comparative community-based case study findings of an investigation of individual-, social- , and structural-level factors that contribute to the HIV/AIDS epidemic among Black Philadelphians. Methods Communities were defined using census tracts. The methodology included ethnographic and GIS mapping, observation, informal conversations with residents and business owners, and secondary analyses of census tract-level data in four Philadelphia neighborhoods. Results Factors such as overcrowding, disadvantage, permeability in community boundaries, and availability and accessibility of health-related resources varied significantly. Further, HIV/AIDS trended with social and structural inequities above and beyond the community’s racial composition. Discussion This study was a first step to disentangle relationships between community-level factors and potential risk for HIV in an HIV epicenter. The findings also highlight stark sociodemographic differences within and across racial groups, and further substantiate the need for comprehensive, community-level HIV prevention interventions. These findings from targeted United States urban communities have potential applicability for examining the distribution of HIV/AIDS in broader national and international geosocial contexts. PMID:25738621

Estimating Kinship in Admixed Populations

PubMed Central

Thornton, Timothy; Tang, Hua; Hoffmann, Thomas J.; Ochs-Balcom, Heather M.; Caan, Bette J.; Risch, Neil

2012-01-01

Genome-wide association studies (GWASs) are commonly used for the mapping of genetic loci that influence complex traits. A problem that is often encountered in both population-based and family-based GWASs is that of identifying cryptic relatedness and population stratification because it is well known that failure to appropriately account for both pedigree and population structure can lead to spurious association. A number of methods have been proposed for identifying relatives in samples from homogeneous populations. A strong assumption of population homogeneity, however, is often untenable, and many GWASs include samples from structured populations. Here, we consider the problem of estimating relatedness in structured populations with admixed ancestry. We propose a method, REAP (relatedness estimation in admixed populations), for robust estimation of identity by descent (IBD)-sharing probabilities and kinship coefficients in admixed populations. REAP appropriately accounts for population structure and ancestry-related assortative mating by using individual-specific allele frequencies at SNPs that are calculated on the basis of ancestry derived from whole-genome analysis. In simulation studies with related individuals and admixture from highly divergent populations, we demonstrate that REAP gives accurate IBD-sharing probabilities and kinship coefficients. We apply REAP to the Mexican Americans in Los Angeles, California (MXL) population sample of release 3 of phase III of the International Haplotype Map Project; in this sample, we identify third- and fourth-degree relatives who have not previously been reported. We also apply REAP to the African American and Hispanic samples from the Women's Health Initiative SNP Health Association Resource (WHI-SHARe) study, in which hundreds of pairs of cryptically related individuals have been identified. PMID:22748210

Consumer preferences, internal color and reduction of shigatoxigenic Escherichia coli in cooked hamburgers.

PubMed

Røssvoll, Elin; Sørheim, Oddvin; Heir, Even; Møretrø, Trond; Olsen, Nina Veflen; Langsrud, Solveig

2014-02-01

The aim of this study was to relate consumer preferences and preparation of hamburgers to color change, internal temperature and reduction of shigatoxigenic Escherichia coli (STEC) serogroups O157 and the "Big Six" (O26, O45, O103, O111, O121, O145) under two ground beef packaging scenarios: 75% O2 MAP and vacuum. 75% O2 MAP hamburgers cooked to 60 °C core temperature appeared done and showed less internal red color (lower a*) than corresponding vacuum hamburgers. Similar STEC reduction (<4 log10) was found for both hamburgers at core temperatures ≤ 66 °C. In a representative survey (N=1046) most consumers reported to judge hamburger doneness by the color and many preferred undercooked hamburgers. Premature browning of 75% O2 MAP hamburgers represents a risk of foodborne illness, when considering consumers' food handling practices. The risk is even greater if such ground beef is prepared by consumers who prefer undercooked hamburgers and judge doneness by color. © 2013.

Application of phyto-indication and radiocesium indicative methods for microrelief mapping

NASA Astrophysics Data System (ADS)

Panidi, E.; Trofimetz, L.; Sokolova, J.

2016-04-01

Remote sensing technologies are widely used for production of Digital Elevation Models (DEMs), and geomorphometry techniques are valuable tools for DEM analysis. One of the broadly used applications of these technologies and techniques is relief mapping. In the simplest case, we can identify relief structures using DEM analysis, and produce a map or map series to show the relief condition. However, traditional techniques might fail when used for mapping microrelief structures (structures below ten meters in size). In this case high microrelief dynamics lead to technological and conceptual difficulties. Moreover, erosion of microrelief structures cannot be detected at the initial evolution stage using DEM modelling and analysis only. In our study, we investigate the possibilities and specific techniques for allocation of erosion microrelief structures, and mapping techniques for the microrelief derivatives (e.g. quantitative parameters of microrelief). Our toolset includes the analysis of spatial redistribution of the soil pollutants and phyto-indication analysis, which complement the common DEM modelling and geomorphometric analysis. We use field surveys produced at the test area, which is arable territory with high erosion risks. Our main conclusion at the current stage is that the indicative methods (i.e. radiocesium and phyto-indication methods) are effective for allocation of the erosion microrelief structures. Also, these methods need to be formalized for convenient use.

Magnetic resonance studies of dissolving particulate solids.

PubMed

Johns, M L; Gladden, L F

2003-01-01

Magnetic resonance methods have been used to elucidate the internal pore structure of particulate solids, in particular detergent tablets. Such information is essential to a comprehensive understanding of the dissolution characteristics of these materials and how this property is related to processing conditions during tablet formation. In particular 3-D images of porosity are produced and 2-D self-diffusion maps are acquired as a function of observation time, which enables pore size to be quantified as a function of position via the extracted surface-to-volume ratio of the pore space. These properties are determined as a function of processing parameters, in particular the compression force used in tablet formation.

Laboratory manager's financial handbook. Cost accounting: the road map to financial success.

PubMed

Travers, E M

1996-01-01

Cost accounting is the most basic element of the laboratory's financial management structure. Historically, cost accounting in the nonmedical world referred to accumulating and assigning costs to units of production and departments, primarily for inventory valuation and income determination. In the health industry, microcost accounting is distinguishable from macrocost (management/internal) accounting and serves multiple purposes. Microcost accounting pertains to gathering and providing information for decision making. The range of decisions include managing recurring operations, making nonrecurring strategic decisions, and formulating major organizational policies. Macrocost accounting fulfills the legal requirements of reporting to stockholders, auditors, governmental agencies, and other external parties.

Implementation of a Configurable Fault Tolerant Processor (CFTP)

DTIC Science & Technology

2003-03-01

internal structure ARCHITECTURE rtl OF log_barrel IS signal sel1, sel2, sel3, sel4 : std_logic_vector ( 1 downto 0); signal buf0b, buf0c...sel3(1) <= l_or_r and shift(2); sel3(0) <= ar_or_log and shift(2); sel4 (1) <= l_or_r and shift(3); sel4 (0) <= ar_or_log and shift(3); buf0b...out_word => buf3a ); mux4: word_mux4 port map ( a => buf3a, b => buf3b, c => buf3c, d => buf3d, sel => sel4

Triple Modular Redundancy (TMR) in a Configurable Fault-Tolerant Processor (CFTP) for Space Applications

DTIC Science & Technology

2003-12-01

internal structure ARCHITECTURE rtl OF log_barrel IS signal sel1, sel2, sel3, sel4 : std_logic_vector ( 1 downto 0); signal buf0b, buf0c, buf0d...shift(2); sel3(0) <= ar_or_log and shift(2); sel4 (1) <= l_or_r and shift(3); sel4 (0) <= ar_or_log and shift(3); buf0b <= in_word(14 downto 0...mux4: word_mux4 port map ( a => buf3a, b => buf3b, c => buf3c, d => buf3d, sel => sel4 , out_word => out_word

Small-Scale Tropopause Dynamics and TOMS Total Ozone

NASA Technical Reports Server (NTRS)

Stanford, John L.

2002-01-01

This project used Earth Probe Total Ozone Mapping Spectrometer (EP TOMS) along-track ozone retrievals, in conjunction with ancillary meteorological fields and modeling studies, for high resolution investigations of upper troposphere and lower stratosphere dynamics. Specifically, high resolution along-track (Level 2) EP TOMS data were used to investigate the beautiful fine-scale structure in constituent and meteorological fields prominent in the evolution of highly non-linear baroclinic storm systems. Comparison was made with high resolution meteorological models. The analyses provide internal consistency checks and validation of the EP TOMS data which are vital for monitoring ozone depletion in both polar and midlatitude regions.

Time-slice maps showing age, distribution, and style of deformation in Alaska north of 60° N.

USGS Publications Warehouse

Moore, Thomas E.; Box, Stephen E.

2016-08-29

The structural architecture of Alaska is the product of a complex history of tectonism that occurred along the Cordilleran and Arctic margins of North America through interactions with ancient and modern ocean plates and with continental elements derived from Laurentia, Siberia, and Baltica. To unravel the tectonic history of Alaska, we constructed maps showing the age, distribution, structural style, and kinematics of contractional and penetrative extensional deformation in Alaska north of latitude 60° N. at a scale of 1:5,000,000. These maps use the Geologic Map of the Arctic (Harrison and others, 2011) as a base map and follow the guidelines in the Tectonic Map of the Arctic project (Petrov and others, 2013) for construction, including use of the International Commission on Stratigraphy time scale (Cohen and others, 2013) divided into 20 time intervals. We find evidence for deformation in 14 of the 20 time intervals and present maps showing the known or probable extent of deformation for each time interval. Maps and descriptions of deformational style, age constraints, kinematics, and information sources for each deformational episode are discussed in the text and are reported in tabular form. This report also contains maps showing the lithologies and structural geology of Alaska, a terrane map, and the distribution of tectonically important units including post-tectonic sedimentary basins, accretionary complexes, ophiolites, metamorphic rocks.These new maps show that most deformational belts in Alaska are relatively young features, having developed during the late Mesozoic and Cenozoic. The oldest episode of deformation recognized anywhere in Alaska is found in the basement of the Farewell terrane (~1.75 Ga). Paleozoic and early Mesozoic deformational events, including Devonian deformation in the Arctic Alaska terrane, Pennsylvanian deformation in the Alexander terrane, Permian deformation in the Yukon Composite (Klondike orogeny) and Farewell terranes (Browns Fork orogeny), Early and Late Jurassic deformation in the Peninsular-Wrangellia terranes, and Early Cretaceous deformation in northern Alaska (early Brookian orogeny) show that within-terrane amalgamation events occurred prior to assembly of Alaska. Widespread episodes of deformation in the Late Cretaceous and early Cenozoic, in contrast, affected multiple terranes, indicating they occurred during or following the time of assembly of most of Alaska.The primary deformational event in northern Alaska was the Late Jurassic and Early Cretaceous (early) Brookian orogeny, which affected most terranes north and west of the early Cenozoic Tintina, Victoria Creek, Kaltag, and Poorman dextral-slip faults in central Alaska. In southern Alaska, formation of the southern Alaska accretionary complex (Chugach, Prince William, Yakutat terranes) and associated magmatism in the Peninsular-Wrangellia terrane began near the Triassic-Jurassic boundary and continued episodically throughout the remainder of the Mesozoic and the Cenozoic. The collision of these terranes with the Farewell and Yukon Composite terranes in central Alaska is recorded by contractional deformation that emanated from the intervening basins in the Late Cretaceous. The boundary between northern and central Alaska is constrained to late Early Cretaceous but is enigmatic and not obviously marked by contractional deformation. Early Cenozoic shortening and transpressional deformation is the most widespread event recorded in Alaska and produced the widespread late Brookian orogenic event in northern Alaska. Middle and late Cenozoic shortening and transpression is significant in southern Alaska inboard of the underthrusting Yakutat terrane at the Pacific margin subduction zone as well as in northeastern Alaska.

High-fidelity national carbon mapping for resource management and REDD+

PubMed Central

2013-01-01

Background High fidelity carbon mapping has the potential to greatly advance national resource management and to encourage international action toward climate change mitigation. However, carbon inventories based on field plots alone cannot capture the heterogeneity of carbon stocks, and thus remote sensing-assisted approaches are critically important to carbon mapping at regional to global scales. We advanced a high-resolution, national-scale carbon mapping approach applied to the Republic of Panama – one of the first UN REDD + partner countries. Results Integrating measurements of vegetation structure collected by airborne Light Detection and Ranging (LiDAR) with field inventory plots, we report LiDAR-estimated aboveground carbon stock errors of ~10% on any 1-ha land parcel across a wide range of ecological conditions. Critically, this shows that LiDAR provides a highly reliable replacement for inventory plots in areas lacking field data, both in humid tropical forests and among drier tropical vegetation types. We then scale up a systematically aligned LiDAR sampling of Panama using satellite data on topography, rainfall, and vegetation cover to model carbon stocks at 1-ha resolution with estimated average pixel-level uncertainty of 20.5 Mg C ha-1 nationwide. Conclusions The national carbon map revealed strong abiotic and human controls over Panamanian carbon stocks, and the new level of detail with estimated uncertainties for every individual hectare in the country sets Panama at the forefront in high-resolution ecosystem management. With this repeatable approach, carbon resource decision-making can be made on a geospatially explicit basis, enhancing human welfare and environmental protection. PMID:23866822

Internal Proteins of the Procapsid and Mature Capsids of Herpes Simplex Virus 1 Mapped by Bubblegram Imaging

PubMed Central

Wu, Weimin; Newcomb, William W.; Cheng, Naiqian; Aksyuk, Anastasia; Winkler, Dennis C.

2016-01-01

ABSTRACT The herpes simplex virus 1 (HSV-1) capsid is a huge assembly, ∼1,250 Å in diameter, and is composed of thousands of protein subunits with a combined mass of ∼200 MDa, housing a 100-MDa genome. First, a procapsid is formed through coassembly of the surface shell with an inner scaffolding shell; then the procapsid matures via a major structural transformation, triggered by limited proteolysis of the scaffolding proteins. Three mature capsids are found in the nuclei of infected cells. A capsids are empty, B capsids retain a shrunken scaffolding shell, and C capsids—which develop into infectious virions—are filled with DNA and ostensibly have expelled the scaffolding shell. The possible presence of other internal proteins in C capsids has been moot as, in cryo-electron microscopy (cryo-EM), they would be camouflaged by the surrounding DNA. We have used bubblegram imaging to map internal proteins in all four capsids, aided by the discovery that the scaffolding protein is exceptionally prone to radiation-induced bubbling. We confirmed that this protein forms thick-walled inner shells in the procapsid and the B capsid. C capsids generate two classes of bubbles: one occupies positions beneath the vertices of the icosahedral surface shell, and the other is distributed throughout its interior. A likely candidate is the viral protease. A subpopulation of C capsids bubbles particularly profusely and may represent particles in which expulsion of scaffold and DNA packaging are incomplete. Based on the procapsid structure, we propose that the axial channels of hexameric capsomers afford the pathway via which the scaffolding protein is expelled. IMPORTANCE In addition to DNA, capsids of tailed bacteriophages and their distant relatives, herpesviruses, contain internal proteins. These proteins are often essential for infectivity but are difficult to locate within the virion. A novel adaptation of cryo-EM based on detecting gas bubbles generated by radiation damage was used to localize internal proteins of HSV-1, yielding insights into how capsid maturation is regulated. The scaffolding protein, which forms inner shells in the procapsid and B capsid, is exceptionally bubbling-prone. In the mature DNA-filled C capsid, a previously undetected protein was found to underlie the icosahedral vertices: this is tentatively assigned as a storage form of the viral protease. We also observed a capsid species that appears to contain substantial amounts of scaffolding protein as well as DNA, suggesting that DNA packaging and expulsion of the scaffolding protein are coupled processes. PMID:26984725

A comparison of cataloged variation between International HapMap Consortium and 1000 Genomes Project data.

PubMed

Buchanan, Carrie C; Torstenson, Eric S; Bush, William S; Ritchie, Marylyn D

2012-01-01

Since publication of the human genome in 2003, geneticists have been interested in risk variant associations to resolve the etiology of traits and complex diseases. The International HapMap Consortium undertook an effort to catalog all common variation across the genome (variants with a minor allele frequency (MAF) of at least 5% in one or more ethnic groups). HapMap along with advances in genotyping technology led to genome-wide association studies which have identified common variants associated with many traits and diseases. In 2008 the 1000 Genomes Project aimed to sequence 2500 individuals and identify rare variants and 99% of variants with a MAF of <1%. To determine whether the 1000 Genomes Project includes all the variants in HapMap, we examined the overlap between single nucleotide polymorphisms (SNPs) genotyped in the two resources using merged phase II/III HapMap data and low coverage pilot data from 1000 Genomes. Comparison of the two data sets showed that approximately 72% of HapMap SNPs were also found in 1000 Genomes Project pilot data. After filtering out HapMap variants with a MAF of <5% (separately for each population), 99% of HapMap SNPs were found in 1000 Genomes data. Not all variants cataloged in HapMap are also cataloged in 1000 Genomes. This could affect decisions about which resource to use for SNP queries, rare variant validation, or imputation. Both the HapMap and 1000 Genomes Project databases are useful resources for human genetics, but it is important to understand the assumptions made and filtering strategies employed by these projects.

Communicating infectious disease prevalence through graphics: results from an international survey

PubMed Central

Fagerlin, Angela; Valley, Thomas S.; Scherer, Aaron M.; Knaus, Megan; Das, Enny; Zikmund-Fisher, Brian J.

2017-01-01

Background Graphics are increasingly used to represent the spread of infectious diseases (e.g., influenza, Zika, Ebola); however, the impact of using graphics to adequately inform the general population is unknown. Objective To examine whether three ways of visually presenting data (heat map, dot map, or picto-trendline)—all depicting the same information regarding the spread of a hypothetical outbreak of influenza—influence intent to vaccinate, risk perception, and knowledge. Design Survey with participants randomized to receive a simulated news article accompanied by one of the three graphics that communicated prevalence of influenza and number of influenza-related deaths. Setting International online survey Participants 16,510 adults living in 11 countries selected using stratified random sampling based on age and gender Measurements After reading the article and viewing the presented graphic, participants completed a survey that measured interest in vaccination, perceived risk of contracting disease, knowledge gained, interest in additional information about the disease, and perception of the graphic. Results Heat maps and picto-trendlines were evaluated more positively than dot maps. Heat maps were more effective than picto-trendlines and no different from dot maps at increasing interest in vaccination, perceived risk of contracting disease, and interest in additional information about the disease. Heat maps and picto-trendlines were more successful at conveying knowledge than dot maps. Overall, heat maps were the only graphic to be superior in every outcome. Limitations Results are based on a hypothetical scenario Conclusion Heat maps are a viable option to promote interest in and concern about infectious diseases. PMID:28647168

Gravity Maps of Antarctic Lithospheric Structure from Remote-Sensing and Seismic Data

NASA Astrophysics Data System (ADS)

Tenzer, Robert; Chen, Wenjin; Baranov, Alexey; Bagherbandi, Mohammad

2018-02-01

Remote-sensing data from altimetry and gravity satellite missions combined with seismic information have been used to investigate the Earth's interior, particularly focusing on the lithospheric structure. In this study, we use the subglacial bedrock relief BEDMAP2, the global gravitational model GOCO05S, and the ETOPO1 topographic/bathymetric data, together with a newly developed (continental-scale) seismic crustal model for Antarctica to compile the free-air, Bouguer, and mantle gravity maps over this continent and surrounding oceanic areas. We then use these gravity maps to interpret the Antarctic crustal and uppermost mantle structure. We demonstrate that most of the gravity features seen in gravity maps could be explained by known lithospheric structures. The Bouguer gravity map reveals a contrast between the oceanic and continental crust which marks the extension of the Antarctic continental margins. The isostatic signature in this gravity map confirms deep and compact orogenic roots under the Gamburtsev Subglacial Mountains and more complex orogenic structures under Dronning Maud Land in East Antarctica. Whereas the Bouguer gravity map exhibits features which are closely spatially correlated with the crustal thickness, the mantle gravity map reveals mainly the gravitational signature of the uppermost mantle, which is superposed over a weaker (long-wavelength) signature of density heterogeneities distributed deeper in the mantle. In contrast to a relatively complex and segmented uppermost mantle structure of West Antarctica, the mantle gravity map confirmed a more uniform structure of the East Antarctic Craton. The most pronounced features in this gravity map are divergent tectonic margins along mid-oceanic ridges and continental rifts. Gravity lows at these locations indicate that a broad region of the West Antarctic Rift System continuously extends between the Atlantic-Indian and Pacific-Antarctic mid-oceanic ridges and it is possibly formed by two major fault segments. Gravity lows over the Transantarctic Mountains confirms their non-collisional origin. Additionally, more localized gravity lows closely coincide with known locations of hotspots and volcanic regions (Marie Byrd Land, Balleny Islands, Mt. Erebus). Gravity lows also suggest a possible hotspot under the South Orkney Islands. However, this finding has to be further verified.

Visual representation of spatiotemporal structure

NASA Astrophysics Data System (ADS)

Schill, Kerstin; Zetzsche, Christoph; Brauer, Wilfried; Eisenkolb, A.; Musto, A.

1998-07-01

The processing and representation of motion information is addressed from an integrated perspective comprising low- level signal processing properties as well as higher-level cognitive aspects. For the low-level processing of motion information we argue that a fundamental requirement is the existence of a spatio-temporal memory. Its key feature, the provision of an orthogonal relation between external time and its internal representation, is achieved by a mapping of temporal structure into a locally distributed activity distribution accessible in parallel by higher-level processing stages. This leads to a reinterpretation of the classical concept of `iconic memory' and resolves inconsistencies on ultra-short-time processing and visual masking. The spatial-temporal memory is further investigated by experiments on the perception of spatio-temporal patterns. Results on the direction discrimination of motion paths provide evidence that information about direction and location are not processed and represented independent of each other. This suggests a unified representation on an early level, in the sense that motion information is internally available in form of a spatio-temporal compound. For the higher-level representation we have developed a formal framework for the qualitative description of courses of motion that may occur with moving objects.

Early Grade Writing Assessment: An Instrument Model.

PubMed

Jiménez, Juan E

The United Nations Educational, Scientific, and Cultural Organization promoted the creation of a model instrument for individual assessment of students' foundational writing skills in the Spanish language that was based on a literature review and existing writing tools and assessments. The purpose of the Early Grade Writing Assessment (EGWA) is to document learners' basic writing skills, mapped in composing units of increasing complexity to communicate meaning. Validation and standardization of EGWA was conducted in the Canary Islands (Spain) in 12 schools using a cross-sectional design with a sample of 1,653 Spanish-speaking students in Grades 1 through 3. The author describes EGWA's internal structure, along with the prevalence of learning disabilities (LD) in transcription and developmental differences in writing between Spanish-speaking children with LD and typical peers. Findings suggest that EGWA's psychometric characteristics are satisfactory, and its internal structure can be attributed to four factors responsible for a high percentage of the variance. The odds ratio indicated that 2 Spanish-speaking children with LD in transcription are identified out of every 100. A comparison between students with and without LD in transcription revealed statistically significant differences concerning sentence and text production across grades. Results are interpreted within current theoretical accounts of writing models.

Relocating San Miguel Volcanic Seismic Events for Receiver Functions and Tomographic Models

NASA Astrophysics Data System (ADS)

Patlan, E.; Velasco, A. A.; Konter, J.

2009-12-01

The San Miguel volcano lies near the city of San Miguel, El Salvador (13.43N and -88.26W). San Miguel volcano, an active stratovolcano, presents a significant natural hazard for the city of San Miguel. Furthermore, the internal state and activity of volcanoes remains an important component to understanding volcanic hazard. The main technology for addressing volcanic hazards and processes is through the analysis of data collected from the deployment of seismic sensors that record ground motion. Six UTEP seismic stations were deployed around San Miguel volcano from 2007-2008 to define the magma chamber and assess the seismic and volcanic hazard. We utilize these data to develop images of the earth structure beneath the volcano, studying the volcanic processes by identifying different sources, and investigating the role of earthquakes and faults in controlling the volcanic processes. We will calculate receiver functions to determine the thickness of San Miguel volcano internal structure, within the Caribbean plate. Crustal thicknesses will be modeled using calculated receiver functions from both theoretical and hand-picked P-wave arrivals. We will use this information derived from receiver functions, along with P-wave delay times, to map the location of the magma chamber.

Geologic Map and Map Database of Eastern Sonoma and Western Napa Counties, California

USGS Publications Warehouse

Graymer, R.W.; Brabb, E.E.; Jones, D.L.; Barnes, J.; Nicholson, R.S.; Stamski, R.E.

2007-01-01

Introduction This report contains a new 1:100,000-scale geologic map, derived from a set of geologic map databases (Arc-Info coverages) containing information at 1:62,500-scale resolution, and a new description of the geologic map units and structural relations in the map area. Prepared as part of the San Francisco Bay Region Mapping Project, the study area includes the north-central part of the San Francisco Bay region, and forms the final piece of the effort to generate new, digital geologic maps and map databases for an area which includes Alameda, Contra Costa, Marin, Napa, San Francisco, San Mateo, Santa Clara, Santa Cruz, Solano, and Sonoma Counties. Geologic mapping in Lake County in the north-central part of the map extent was not within the scope of the Project. The map and map database integrates both previously published reports and new geologic mapping and field checking by the authors (see Sources of Data index map on the map sheet or the Arc-Info coverage eswn-so and the textfile eswn-so.txt). This report contains new ideas about the geologic structures in the map area, including the active San Andreas Fault system, as well as the geologic units and their relations. Together, the map (or map database) and the unit descriptions in this report describe the composition, distribution, and orientation of geologic materials and structures within the study area at regional scale. Regional geologic information is important for analysis of earthquake shaking, liquifaction susceptibility, landslide susceptibility, engineering materials properties, mineral resources and hazards, as well as groundwater resources and hazards. These data also assist in answering questions about the geologic history and development of the California Coast Ranges.

Concept Mapping: A Graphical System for Understanding the Relationship between Concepts. ERIC Digest.

ERIC Educational Resources Information Center

Plotnick, Eric

This ERIC Digest discusses concept mapping, a technique for representing the structure of information visually. Concept mapping can be used to brainstorm, design complex structures, communicate complex ideas, aid learning by explicitly integrating new and old knowledge, and assess understanding or diagnose misunderstanding. Visual representation…

Comment on "How can seismic hazard around the New Madrid seismic zone be similar to that in California?" by Arthur Frankel

USGS Publications Warehouse

Wang, Z.; Shi, B.; Kiefer, J.D.

2005-01-01

PSHA is the method used most to assess seismic hazards for input into various aspects of public and financial policy. For example, PSHA was used by the U.S. Geological Survey to develop the National Seismic Hazard Maps (Frankel et al., 1996, 2002). These maps are the basis for many national, state, and local seismic safety regulations and design standards, such as the NEHRP Recommended Provisions for Seismic Regulations for New Buildings and Other Structures, the International Building Code, and the International Residential Code. Adoption and implementation of these regulations and design standards would have significant impacts on many communities in the New Madrid area, including Memphis, Tennessee and Paducah, Kentucky. Although "mitigating risks to society from earthquakes involves economic and policy issues" (Stein, 2004), seismic hazard assessment is the basis. Seismologists should provide the best information on seismic hazards and communicate them to users and policy makers. There is a lack of effort in communicating the uncertainties in seismic hazard assessment in the central U.S., however. Use of 10%, 5%, and 2% PE in 50 years causes confusion in communicating seismic hazard assessment. It would be easy to discuss and understand the design ground motions if the true meaning of the ground motion derived from PSHA were presented, i.e., the ground motion with the estimated uncertainty or the associated confidence level.

Low rank approximation methods for MR fingerprinting with large scale dictionaries.

PubMed

Yang, Mingrui; Ma, Dan; Jiang, Yun; Hamilton, Jesse; Seiberlich, Nicole; Griswold, Mark A; McGivney, Debra

2018-04-01

This work proposes new low rank approximation approaches with significant memory savings for large scale MR fingerprinting (MRF) problems. We introduce a compressed MRF with randomized singular value decomposition method to significantly reduce the memory requirement for calculating a low rank approximation of large sized MRF dictionaries. We further relax this requirement by exploiting the structures of MRF dictionaries in the randomized singular value decomposition space and fitting them to low-degree polynomials to generate high resolution MRF parameter maps. In vivo 1.5T and 3T brain scan data are used to validate the approaches. T 1 , T 2 , and off-resonance maps are in good agreement with that of the standard MRF approach. Moreover, the memory savings is up to 1000 times for the MRF-fast imaging with steady-state precession sequence and more than 15 times for the MRF-balanced, steady-state free precession sequence. The proposed compressed MRF with randomized singular value decomposition and dictionary fitting methods are memory efficient low rank approximation methods, which can benefit the usage of MRF in clinical settings. They also have great potentials in large scale MRF problems, such as problems considering multi-component MRF parameters or high resolution in the parameter space. Magn Reson Med 79:2392-2400, 2018. © 2017 International Society for Magnetic Resonance in Medicine. © 2017 International Society for Magnetic Resonance in Medicine.

Fundamental constructs in food parenting practices: a content map to guide future research.

PubMed

Vaughn, Amber E; Ward, Dianne S; Fisher, Jennifer O; Faith, Myles S; Hughes, Sheryl O; Kremers, Stef P J; Musher-Eizenman, Dara R; O'Connor, Teresia M; Patrick, Heather; Power, Thomas G

2016-02-01

Although research shows that "food parenting practices" can impact children's diet and eating habits, current understanding of the impact of specific practices has been limited by inconsistencies in terminology and definitions. This article represents a critical appraisal of food parenting practices, including clear terminology and definitions, by a working group of content experts. The result of this effort was the development of a content map for future research that presents 3 overarching, higher-order food parenting constructs--coercive control, structure, and autonomy support--as well as specific practice subconstructs. Coercive control includes restriction, pressure to eat, threats and bribes, and using food to control negative emotions. Structure includes rules and limits, limited/guided choices, monitoring, meal- and snacktime routines, modeling, food availability and accessibility, food preparation, and unstructured practices. Autonomy support includes nutrition education, child involvement, encouragement, praise, reasoning, and negotiation. Literature on each construct is reviewed, and directions for future research are offered. Clear terminology and definitions should facilitate cross-study comparisons and minimize conflicting findings resulting from previous discrepancies in construct operationalization. © The Author(s) 2016. Published by Oxford University Press on behalf of the International Life Sciences Institute. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Communication: Origin of the contributions to DNA structure in phages

PubMed Central

Myers, Christopher G.; Pettitt, B. Montgomery

2013-01-01

Cryo electron microscopy (cryo-EM) data of the interior of phages show ordering of the interior DNA that has been interpreted as a nearly perfectly ordered polymer. We show surface-induced correlations, excluded volume, and electrostatic forces are sufficient to predict most of the major features of the current structural data for DNA packaged within viral capsids without additional ordering due to elastic bending forces for the polymer. Current models assume highly-ordered, even spooled, hexagonally packed conformations based on interpretation of cryo-EM density maps. We show herein that the surface induced packing of short (6mer), unconnected DNA polymer segments is the only necessary ingredient in creating ringed densities consistent with experimental density maps. This implies the ensemble of possible conformations of polymeric DNA within the capsid that are consistent with cryo-EM data may be much larger than implied by traditional interpretations where such rings can only result from highly-ordered spool-like conformations. This opens the possibility of a more disordered, entropically-driven view of phage packaging thermodynamics. We also show the electrostatics of the DNA contributes a large portion of the internal hydrostatic and osmotic pressures of a phage virion, suggesting that nonlinear elastic anomalies might reduce the overall elastic bending enthalpy of more disordered conformations to have allowable free energies. PMID:23444988

Communication: Origin of the contributions to DNA structure in phages.

PubMed

Myers, Christopher G; Pettitt, B Montgomery

2013-02-21

Cryo electron microscopy (cryo-EM) data of the interior of phages show ordering of the interior DNA that has been interpreted as a nearly perfectly ordered polymer. We show surface-induced correlations, excluded volume, and electrostatic forces are sufficient to predict most of the major features of the current structural data for DNA packaged within viral capsids without additional ordering due to elastic bending forces for the polymer. Current models assume highly-ordered, even spooled, hexagonally packed conformations based on interpretation of cryo-EM density maps. We show herein that the surface induced packing of short (6mer), unconnected DNA polymer segments is the only necessary ingredient in creating ringed densities consistent with experimental density maps. This implies the ensemble of possible conformations of polymeric DNA within the capsid that are consistent with cryo-EM data may be much larger than implied by traditional interpretations where such rings can only result from highly-ordered spool-like conformations. This opens the possibility of a more disordered, entropically-driven view of phage packaging thermodynamics. We also show the electrostatics of the DNA contributes a large portion of the internal hydrostatic and osmotic pressures of a phage virion, suggesting that nonlinear elastic anomalies might reduce the overall elastic bending enthalpy of more disordered conformations to have allowable free energies.

Medical Image Fusion Based on Feature Extraction and Sparse Representation

PubMed Central

Wei, Gao; Zongxi, Song

2017-01-01

As a novel multiscale geometric analysis tool, sparse representation has shown many advantages over the conventional image representation methods. However, the standard sparse representation does not take intrinsic structure and its time complexity into consideration. In this paper, a new fusion mechanism for multimodal medical images based on sparse representation and decision map is proposed to deal with these problems simultaneously. Three decision maps are designed including structure information map (SM) and energy information map (EM) as well as structure and energy map (SEM) to make the results reserve more energy and edge information. SM contains the local structure feature captured by the Laplacian of a Gaussian (LOG) and EM contains the energy and energy distribution feature detected by the mean square deviation. The decision map is added to the normal sparse representation based method to improve the speed of the algorithm. Proposed approach also improves the quality of the fused results by enhancing the contrast and reserving more structure and energy information from the source images. The experiment results of 36 groups of CT/MR, MR-T1/MR-T2, and CT/PET images demonstrate that the method based on SR and SEM outperforms five state-of-the-art methods. PMID:28321246

Portability issues for a structured clinical vocabulary: mapping from Yale to the Columbia medical entities dictionary.

PubMed Central

Kannry, J L; Wright, L; Shifman, M; Silverstein, S; Miller, P L

1996-01-01

OBJECTIVE: To examine the issues involved in mapping an existing structured controlled vocabulary, the Medical Entities Dictionary (MED) developed at Columbia University, to an institutional vocabulary, the laboratory and pharmacy vocabularies of the Yale New Haven Medical Center. DESIGN: 200 Yale pharmacy terms and 200 Yale laboratory terms were randomly selected from database files containing all of the Yale laboratory and pharmacy terms. These 400 terms were then mapped to the MED in three phases: mapping terms, mapping relationships between terms, and mapping attributes that modify terms. RESULTS: 73% of the Yale pharmacy terms mapped to MED terms. 49% of the Yale laboratory terms mapped to MED terms. After certain obsolete and otherwise inappropriate laboratory terms were eliminated, the latter rate improved to 59%. 23% of the unmatched Yale laboratory terms failed to match because of differences in granularity with MED terms. The Yale and MED pharmacy terms share 12 of 30 distinct attributes. The Yale and MED laboratory terms share 14 of 23 distinct attributes. CONCLUSION: The mapping of an institutional vocabulary to a structured controlled vocabulary requires that the mapping be performed at the level of terms, relationships, and attributes. The mapping process revealed the importance of standardization of local vocabulary subsets, standardization of attribute representation, and term granularity. PMID:8750391

The Shape, Internal Structure and Dynamics of 433 Eros from the NEAR Laser Ranging Investigation

NASA Astrophysics Data System (ADS)

Zuber, M. T.; Smith, D. E.; Cheng, A. F.; Garvin, J. B.; NLR Science Team

2000-10-01

The NEAR Laser Rangefinder, an instrument on the NEAR-Shoemaker spacecraft, has been mapping the detailed shape of asteroid 433 Eros since February 29, 2000. The instrument has a range resolution of 31 cm and a surface spot size that varies between 8 to 45 m (depending on orbital altitude), yielding along-track profiles that are often contiguous or overlapping. The NLR has so far provided over 7 million valid measurements of the range from the NEAR-Shoemaker spacecraft to the surface of 433 Eros, which are converted to mass-centered radii through solutions for the spacecraft orbit from Doppler tracking. The current spherical harmonic model, produced in a joint solution between altimetry and Doppler, is to degree and order 48 and is characterized by a spatial resolution of 470 m and a vertical accuracy of a few tens of meters. The shape model has an RMS misfit of 1000 +/- 126 m to an ellipsoid, which represents a poor fit compared to other measured asteroids. Eros' complex shape was dominated by collisions but the asteroid shows no evidence of dumbbell-like structure suggestive of a contact binary bound loosely by self-gravitation. Clustered regions of high slopes on the walls of the two largest depressions represent evidence for structural competence. The offset between the asteroid's center of mass and center of figure can be explained by a density gradient of only 4.3 kg m-3 km-1. This minor deviation of internal structure from homogeneity is likely due to variations in mechanical competence (regolith distribution and variations in internal porosity) rather than composition. Regolith thicknesses of a few tens of meters are inferred from depths of topographic benches in craters. Impact crater morphology shows evidence of influence from both gravity and structural control. Small-scale topography reveals ridges and grooves likely generated by impact-related fracturing.

Recent advances in standards for collaborative Digital Anatomic Pathology

PubMed Central

2011-01-01

Context Collaborative Digital Anatomic Pathology refers to the use of information technology that supports the creation and sharing or exchange of information, including data and images, during the complex workflow performed in an Anatomic Pathology department from specimen reception to report transmission and exploitation. Collaborative Digital Anatomic Pathology can only be fully achieved using medical informatics standards. The goal of the international integrating the Healthcare Enterprise (IHE) initiative is precisely specifying how medical informatics standards should be implemented to meet specific health care needs and making systems integration more efficient and less expensive. Objective To define the best use of medical informatics standards in order to share and exchange machine-readable structured reports and their evidences (including whole slide images) within hospitals and across healthcare facilities. Methods Specific working groups dedicated to Anatomy Pathology within multiple standards organizations defined standard-based data structures for Anatomic Pathology reports and images as well as informatic transactions in order to integrate Anatomic Pathology information into the electronic healthcare enterprise. Results The DICOM supplements 122 and 145 provide flexible object information definitions dedicated respectively to specimen description and Whole Slide Image acquisition, storage and display. The content profile “Anatomic Pathology Structured Report” (APSR) provides standard templates for structured reports in which textual observations may be bound to digital images or regions of interest. Anatomic Pathology observations are encoded using an international controlled vocabulary defined by the IHE Anatomic Pathology domain that is currently being mapped to SNOMED CT concepts. Conclusion Recent advances in standards for Collaborative Digital Anatomic Pathology are a unique opportunity to share or exchange Anatomic Pathology structured reports that are interoperable at an international level. The use of machine-readable format of APSR supports the development of decision support as well as secondary use of Anatomic Pathology information for epidemiology or clinical research. PMID:21489187

Vastly accelerated linear least-squares fitting with numerical optimization for dual-input delay-compensated quantitative liver perfusion mapping.

PubMed

Jafari, Ramin; Chhabra, Shalini; Prince, Martin R; Wang, Yi; Spincemaille, Pascal

2018-04-01

To propose an efficient algorithm to perform dual input compartment modeling for generating perfusion maps in the liver. We implemented whole field-of-view linear least squares (LLS) to fit a delay-compensated dual-input single-compartment model to very high temporal resolution (four frames per second) contrast-enhanced 3D liver data, to calculate kinetic parameter maps. Using simulated data and experimental data in healthy subjects and patients, whole-field LLS was compared with the conventional voxel-wise nonlinear least-squares (NLLS) approach in terms of accuracy, performance, and computation time. Simulations showed good agreement between LLS and NLLS for a range of kinetic parameters. The whole-field LLS method allowed generating liver perfusion maps approximately 160-fold faster than voxel-wise NLLS, while obtaining similar perfusion parameters. Delay-compensated dual-input liver perfusion analysis using whole-field LLS allows generating perfusion maps with a considerable speedup compared with conventional voxel-wise NLLS fitting. Magn Reson Med 79:2415-2421, 2018. © 2017 International Society for Magnetic Resonance in Medicine. © 2017 International Society for Magnetic Resonance in Medicine.

A regional ionospheric TEC mapping technique over China and adjacent areas on the basis of data assimilation

NASA Astrophysics Data System (ADS)

Aa, Ercha; Huang, Wengeng; Yu, Shimei; Liu, Siqing; Shi, Liqin; Gong, Jiancun; Chen, Yanhong; Shen, Hua

2015-06-01

In this paper, a regional total electron content (TEC) mapping technique over China and adjacent areas (70°E-140°E and 15°N-55°N) is developed on the basis of a Kalman filter data assimilation scheme driven by Global Navigation Satellite Systems (GNSS) data from the Crustal Movement Observation Network of China and International GNSS Service. The regional TEC maps can be generated accordingly with the spatial and temporal resolution being 1°×1° and 5 min, respectively. The accuracy and quality of the TEC mapping technique have been validated through the comparison with GNSS observations, the International Reference Ionosphere model values, the global ionosphere maps from Center for Orbit Determination of Europe, and the Massachusetts Institute of Technology Automated Processing of GPS TEC data from Madrigal database. The verification results indicate that great systematic improvements can be obtained when data are assimilated into the background model, which demonstrates the effectiveness of this technique in providing accurate regional specification of the ionospheric TEC over China and adjacent areas.

Monitoring and analysis of the change process in curriculum mapping compared to the National Competency-based Learning Objective Catalogue for Undergraduate Medical Education (NKLM) at four medical faculties. Part I: Conducive resources and structures

PubMed Central

Lammerding-Koeppel, Maria; Giesler, Marianne; Gornostayeva, Maryna; Narciss, Elisabeth; Wosnik, Annette; Zipfel, Stephan; Griewatz, Jan; Fritze, Olaf

2017-01-01

Objective: After passing of the National Competency-based Learning Objectives Catalogue in Medicine (Nationaler Kompetenzbasierter Lernzielkatalog Medizin, [NKLM, retrieved on 22.03.2016]), the German medical faculties must take inventory and develop their curricula. NKLM contents are expected to be present, but not linked well or sensibly enough in locally grown curricula. Learning and examination formats must be reviewed for appropriateness and coverage of the competences. The necessary curricular transparency is best achieved by systematic curriculum mapping, combined with effective change management. Mapping a complex existing curriculum and convincing a faculty that this will have benefits is not easy. Headed by Tübingen, the faculties of Freiburg, Heidelberg, Mannheim and Tübingen take inventory by mapping their curricula in comparison to the NKLM, using the dedicated web-based MERLIN-database. This two-part article analyses and summarises how NKLM curriculum mapping could be successful in spite of resistance at the faculties. The target is conveying the widest possible overview of beneficial framework conditions, strategies and results. Part I of the article shows the beneficial resources and structures required for implementation of curriculum mapping at the faculties. Part II describes key factors relevant for motivating faculties and teachers during the mapping process. Method: The network project was systematically planned in advance according to steps of project and change management, regularly reflected on and adjusted together in workshops and semi-annual project meetings. From the beginning of the project, a grounded-theory approach was used to systematically collect detailed information on structures, measures and developments at the faculties using various sources and methods, to continually analyse them and to draw a final conclusion (sources: surveys among the project participants with questionnaires, semi-structured group interviews and discussions, guideline-supported individual interviews, informal surveys, evaluation of target agreements and protocols, openly discernible local, regional or over-regional structure-relevant events). Results: The following resources and structures support implementation of curriculum mapping at a faculty: Setting up a coordination agency (≥50% of a full position; support by student assistants), systematic project management, and development of organisation and communication structures with integration of the dean of study and teaching and pilot departments, as well as development of a user-friendly web-based mapping instrument. Acceptance of the mapping was increased particularly by visualisation of the results and early insight into indicative results relevant for the department. Conclusion: Successful NKLM curriculum mapping requires trained staff for coordination, resilient communication structures and a user-oriented mapping database. In alignment with literature, recommendations can be derived to support other faculties that want to map their curriculum. PMID:28293674

Monitoring and analysis of the change process in curriculum mapping compared to the National Competency-based Learning Objective Catalogue for Undergraduate Medical Education (NKLM) at four medical faculties. Part I: Conducive resources and structures.

PubMed

Lammerding-Koeppel, Maria; Giesler, Marianne; Gornostayeva, Maryna; Narciss, Elisabeth; Wosnik, Annette; Zipfel, Stephan; Griewatz, Jan; Fritze, Olaf

2017-01-01

Objective: After passing of the National Competency-based Learning Objectives Catalogue in Medicine (Nationaler Kompetenzbasierter Lernzielkatalog Medizin, [NKLM, retrieved on 22.03.2016]), the German medical faculties must take inventory and develop their curricula. NKLM contents are expected to be present, but not linked well or sensibly enough in locally grown curricula. Learning and examination formats must be reviewed for appropriateness and coverage of the competences. The necessary curricular transparency is best achieved by systematic curriculum mapping, combined with effective change management. Mapping a complex existing curriculum and convincing a faculty that this will have benefits is not easy. Headed by Tübingen, the faculties of Freiburg, Heidelberg, Mannheim and Tübingen take inventory by mapping their curricula in comparison to the NKLM, using the dedicated web-based MER LIN -database. This two-part article analyses and summarises how NKLM curriculum mapping could be successful in spite of resistance at the faculties. The target is conveying the widest possible overview of beneficial framework conditions, strategies and results. Part I of the article shows the beneficial resources and structures required for implementation of curriculum mapping at the faculties. Part II describes key factors relevant for motivating faculties and teachers during the mapping process. Method: The network project was systematically planned in advance according to steps of project and change management, regularly reflected on and adjusted together in workshops and semi-annual project meetings. From the beginning of the project, a grounded-theory approach was used to systematically collect detailed information on structures, measures and developments at the faculties using various sources and methods, to continually analyse them and to draw a final conclusion (sources: surveys among the project participants with questionnaires, semi-structured group interviews and discussions, guideline-supported individual interviews, informal surveys, evaluation of target agreements and protocols, openly discernible local, regional or over-regional structure-relevant events). Results: The following resources and structures support implementation of curriculum mapping at a faculty: Setting up a coordination agency (≥50% of a full position; support by student assistants), systematic project management, and development of organisation and communication structures with integration of the dean of study and teaching and pilot departments, as well as development of a user-friendly web-based mapping instrument. Acceptance of the mapping was increased particularly by visualisation of the results and early insight into indicative results relevant for the department. Conclusion: Successful NKLM curriculum mapping requires trained staff for coordination, resilient communication structures and a user-oriented mapping database. In alignment with literature, recommendations can be derived to support other faculties that want to map their curriculum.

Polder maps: Improving OMIT maps by excluding bulk solvent

DOE PAGES

Liebschner, Dorothee; Afonine, Pavel V.; Moriarty, Nigel W.; ...

2017-02-01

The crystallographic maps that are routinely used during the structure-solution workflow are almost always model-biased because model information is used for their calculation. As these maps are also used to validate the atomic models that result from model building and refinement, this constitutes an immediate problem: anything added to the model will manifest itself in the map and thus hinder the validation. OMIT maps are a common tool to verify the presence of atoms in the model. The simplest way to compute an OMIT map is to exclude the atoms in question from the structure, update the corresponding structure factorsmore » and compute a residual map. It is then expected that if these atoms are present in the crystal structure, the electron density for the omitted atoms will be seen as positive features in this map. This, however, is complicated by the flat bulk-solvent model which is almost universally used in modern crystallographic refinement programs. This model postulates constant electron density at any voxel of the unit-cell volume that is not occupied by the atomic model. Consequently, if the density arising from the omitted atoms is weak then the bulk-solvent model may obscure it further. A possible solution to this problem is to prevent bulk solvent from entering the selected OMIT regions, which may improve the interpretative power of residual maps. This approach is called a polder (OMIT) map. Polder OMIT maps can be particularly useful for displaying weak densities of ligands, solvent molecules, side chains, alternative conformations and residues both in terminal regions and in loops. As a result, the tools described in this manuscript have been implemented and are available in PHENIX.« less

Seafloor Mapping: We've Come a Long Way - But Still Have Far to Go……

NASA Astrophysics Data System (ADS)

Mayer, L. A.

2017-12-01

Our ability to map the seafloor has changed radically over the past century. For thousands of years a weight at the end of a rope (or wire) - a lead line - provided the only means to measure depth. By the end of the Second World War, single beam echo sounders had been perfected to the extent that they became common on oceanographic and other vessels providing more rapid but laterally averaged (typically over a distance commensurate with the water depth) measurements of seafloor depths. Towards the end of the 20th Century - two great advances were made in seafloor mapping - the development of techniques to use satellite altimetry to predict seafloor bathymetry and the evolution of multibeam sonar technology from classified military applications to the academic and commercial communities. Satellite-altimetry derived bathymetry provides an unprecedented view of seafloor topography and tremendous insight into tectonic-scale processes but is limited in achievable resolution. Multibeam sonars offer the potential of extremely high-resolution (a function of array size, beam footprint, and water depth), but are typically deployed from manned surface vessels that cover limited amount of seafloor at a relatively high daily cost. We have the technology to map the entire world ocean with multibeam sonar but It has been estimated that to map the world ocean deeper than about 150m (shallow water is very time-consuming and expensive because the coverage swath width is typically 3-5 times water) would take approximately 200 ship years and cost on the order of 3 billion dollars. We have demonstrated our willingness to spend billions to map other planets (e.g. Mars and the Moon) but for some reason, not our own. Recently, however, there has been growing momentum to see the entire world ocean mapped. The Nippon Foundation and GEBCO have recently announced the Seabed 2030 project with a goal of facilitating the mapping of the world ocean by 2030 and international agreements like The Galway Statement on Atlantic Cooperation are coordinating international efforts to see large portions of the seafloor mapped. Coupled with these international efforts, new technologies like autonomous mapping barges or large-scale multibeam sonar equipped Saildrones may greatly reduce costs and make the dream of mapping the world ocean at high-resolution a reality.

An ODIP effort to map R2R ocean data terms to international vocabularies

NASA Astrophysics Data System (ADS)

Ferreira, Renata; Stocks, Karen; Arko, Robert

2014-05-01

The heterogeneity of terminology used in describing data creates a barrier to the efficient discovery and re-use of data, particularly across institutional, programmatic, and disciplinary boundaries. Here we explore the outcomes of a student project to crosswalk terms between the Rolling Deck to Repository (R2R) program and other international systems, as part of the Ocean Data Interoperability Platform (ODIP). R2R is a US program developing and implementing an information management system to preserve and provide access to routine underway data collected by U.S academic research vessels. R2R participates in ODIP, an international forum for improving the interoperability and effective sharing of marine data resources through technical workshops and joint prototypes. The vocabulary mapping effort lays a foundation for future ocean data portals through which users search and access international ocean data using familiar terms. R2R describes its data with a suite of controlled vocabularies (http://www.rvdata.us/voc) some of which were developed locally or are specific to the US. The goal of this student project is to crosswalk local/national vocabularies to authoritative international vocabularies, where they exist, or to vocabularies widely used by ODIP partners. Specifically, R2R developed the following crosswalks: R2R science party names to ORCID person identifiers, UNOLS ports to SeaDataNet Ports Gazetteer, R2R Device Models to NVS SeaVoX Device Catalog, and R2R Organizations to the European Directory of Marine Organizations (EDMO). Mappings were done in simple spreadsheets using synonymy relationships only, and will be published as part of the R2R Linked Data resources. The level of success in crosswalking was variable. The majority of ports were successfully mapped. Differences in the character sets (i.e. whether diacritic marks were used) caused automated matching to fail occasionally, but the number of ports was small enough that these could be manually reviewed. Both organizations and device models have initial mappings, and R2R will propose new terms to the EDMO and SeaVoX Device vocabularies to complete coverage. Mapping to ORCID identifiers was abandoned (though R2R will still hold and expose them when supplied by the data provider). Most ORCID entries do not contain insufficient metadata to confirm potential mappings: the match of a family and given name was considered inconclusive without further support. ORCID also does not assign identifiers posthumously, which is occasionally necessary for historical data in R2R.

Facet Theory and the Mapping Sentence As Hermeneutically Consistent Structured Meta-Ontology and Structured Meta-Mereology

PubMed Central

Hackett, Paul M. W.

2016-01-01

When behavior is interpreted in a reliable manner (i.e., robustly across different situations and times) its explained meaning may be seen to possess hermeneutic consistency. In this essay I present an evaluation of the hermeneutic consistency that I propose may be present when the research tool known as the mapping sentence is used to create generic structural ontologies. I also claim that theoretical and empirical validity is a likely result of employing the mapping sentence in research design and interpretation. These claims are non-contentious within the realm of quantitative psychological and behavioral research. However, I extend the scope of both facet theory based research and claims for its structural utility, reliability and validity to philosophical and qualitative investigations. I assert that the hermeneutic consistency of a structural ontology is a product of a structural representation's ontological components and the mereological relationships between these ontological sub-units: the mapping sentence seminally allows for the depiction of such structure. PMID:27065932

G2S: a web-service for annotating genomic variants on 3D protein structures.

PubMed

Wang, Juexin; Sheridan, Robert; Sumer, S Onur; Schultz, Nikolaus; Xu, Dong; Gao, Jianjiong

2018-06-01

Accurately mapping and annotating genomic locations on 3D protein structures is a key step in structure-based analysis of genomic variants detected by recent large-scale sequencing efforts. There are several mapping resources currently available, but none of them provides a web API (Application Programming Interface) that supports programmatic access. We present G2S, a real-time web API that provides automated mapping of genomic variants on 3D protein structures. G2S can align genomic locations of variants, protein locations, or protein sequences to protein structures and retrieve the mapped residues from structures. G2S API uses REST-inspired design and it can be used by various clients such as web browsers, command terminals, programming languages and other bioinformatics tools for bringing 3D structures into genomic variant analysis. The webserver and source codes are freely available at https://g2s.genomenexus.org. g2s@genomenexus.org. Supplementary data are available at Bioinformatics online.

Bedrock and structural geologic maps of eastern Candor Sulci, western Ceti Mensa, and southeastern Ceti Mensa, Candor Chasma, Valles Marineris region of Mars

USGS Publications Warehouse

Okubo, Chris H.; Gaither, Tenielle A.

2017-05-12

This map product contains a set of three 1:18,000-scale maps showing the geology and structure of study areas in the western Candor Chasma region of Valles Marineris, Mars. These maps are part of an informal series of large-scale maps and map-based topical studies aimed at refining current understanding of the geologic history of western Candor Chasma. The map bases consist of digital elevation models and orthorectified images derived from High Resolution Imaging Science Experiment (HiRISE) data. These maps are accompanied by geologic cross sections, colorized elevation maps, and cutouts of HiRISE images showing key superposition relations. Also included in this product is a Correlation of Map Units that integrates units across all three map areas, as well as an integrated Description of Map Units and an integrated Explanation of Map Symbols. The maps were assembled using ArcGIS software produced by Environmental Systems Research Institute (http://www.esri.com). The ArcGIS projects and databases associated with each map are included online as supplemental data.

FOLD-EM: automated fold recognition in medium- and low-resolution (4-15 Å) electron density maps.

PubMed

Saha, Mitul; Morais, Marc C

2012-12-15

Owing to the size and complexity of large multi-component biological assemblies, the most tractable approach to determining their atomic structure is often to fit high-resolution radiographic or nuclear magnetic resonance structures of isolated components into lower resolution electron density maps of the larger assembly obtained using cryo-electron microscopy (cryo-EM). This hybrid approach to structure determination requires that an atomic resolution structure of each component, or a suitable homolog, is available. If neither is available, then the amount of structural information regarding that component is limited by the resolution of the cryo-EM map. However, even if a suitable homolog cannot be identified using sequence analysis, a search for structural homologs should still be performed because structural homology often persists throughout evolution even when sequence homology is undetectable, As macromolecules can often be described as a collection of independently folded domains, one way of searching for structural homologs would be to systematically fit representative domain structures from a protein domain database into the medium/low resolution cryo-EM map and return the best fits. Taken together, the best fitting non-overlapping structures would constitute a 'mosaic' backbone model of the assembly that could aid map interpretation and illuminate biological function. Using the computational principles of the Scale-Invariant Feature Transform (SIFT), we have developed FOLD-EM-a computational tool that can identify folded macromolecular domains in medium to low resolution (4-15 Å) electron density maps and return a model of the constituent polypeptides in a fully automated fashion. As a by-product, FOLD-EM can also do flexible multi-domain fitting that may provide insight into conformational changes that occur in macromolecular assemblies.

New mapping of Radlandi basin and detailed analysis of its inner plains

NASA Astrophysics Data System (ADS)

Minelli, Francesco; Giorgetti, Carolina; Mondini, Alessandro; Pauselli, Cristina; Mancinelli, Paolo

2013-04-01

NEW MAPPING OF RADITLADI BASIN AND DETAILED ANALYSIS OF ITS INNER PLAINS. Francesco Minelli 1, Carolina Giorgetti 1, Alessandro C. Mondini 2, Cristina Pauselli 1, Paolo Mancinelli1. 1 Gruppo di Geologia Strutturale e Geofisica (GSG), Dipartimento di Scienze della Terra, Università degli Studi di Perugia, 06123, Perugia, Italy . Email: minelli91@yahoo.it. 2 CNR IRPI Perugia, 06123, Perugia. Introduction: The Raditladi basin is a large peak-ring impact crater discovered during the MESSENGER (MErcury Surface, Space ENvironment, GEochemistry, and Ranging) first flyby of Mercury in January 2008 [1]. The Raditladi basin is relatively young [2], and the study of the internal structures give an indication of the processes that acted recently in Mercury's geological history. Geological mapping: We first present the geological mapping of Raditladi crater. In the map we defined different sub-units on the base of previous studies [4][5] and surface morphology and reflectance. Through a GIS software we associated a polygonal layer to each sub-unit, this allowed to distinguish nine different layers. Due to the similarities with the Rachmaninoff basin, to define sub-units mapped on Raditladi, we adopted Rachmaninoff crater's units definitions made by Marchi et al. (2011) [4]. Structures analysis : We also mapped secondary structures consisting in concentric troughs arranged in a circular pattern. We defined two different kinds of troughs: (i) structures characterized by a distinct flat floor and interpretable as grabens, and (ii) structures with linear and curvilinear segments [5]. Inner plain deposit: The analysis of the topography made possible the estimation of the deposit's thickness. The measurement of the thickness is possible thanks to the presence of two small craters, crater A and crater, located in Raditladi's Inner plain. Observing the morphology of the two small craters' rim and hummocky central floor, we distinguished two different units: the shallower consists in thin material [6] and the deeper consists in shocked surface. To estimate the deposit thickness, we realized two sections across the two craters, we considered the rim uplift due to the stratigraphic doubling [7], and the depth at which we observed the shocked surface situated below the surficial deposit. Moreover the two craters, one near the center and the other near the peak ring, allowed us to observe the variation of the deposit's thickness: tracing a section that cuts both the craters is possible to appreciate its thinning towards the basin center. On the base of impact crater experiment made by Takita & Sumita (2011) [6] we supposed that the deposit consist in a thin upper layer of material with a fine granulometry. The deposit thickness measured in the crater B, near the peak ring, is 839 m and in the crater A, near the basin center, is 846 m. In conclusion, the obtained values, differing only for 7 m, show an approximately constant thickness of the deposit from the basin center, where the values is slightly greater, to the peak ring. References: [1] Solomon S.C. et al. (2008) Science, 321, 59-62.[2] Strom R.G. et al. (2008) Science, 321, 79. [3] Hawkins S.E. et al. (2007) Space Sci. Rev., 131, 247-338[4] Marchi S. et al. (2011) Planet. Space Sci, 59, 1968-1980. [5] Prockter L.M. et al. (2009) Lunar Planet. Sci. Conf. Abstract, 40, 1758. [6] Takita H. & Sumita I. (2011) Japan Geoscience Union Meeting 2011, PPS020-P05. [7] H.J. Melosh (1989) Oxford Monographs on Geology and Geophysics Series, 11.

IBMISPS (International Brain Mapping & Intraoperative Surgical Planning Symposium)

DTIC Science & Technology

2005-12-01

they received the 2005 Excellence in R, D & E award for their contribution in the feild of prosthetics and brain imaging. Excellence in Educational...specific bipolar magnetic gradient pulses which measure the velocity vector components of motion. Presented here are the development of dynamic MR...movies of quantitative velocity vector components, 30 frames per second. The 3 velocity vector maps with tensor analysis produced maps of the

Countries of the World and International Organizations: Sources of Information

DTIC Science & Technology

2007-01-08

provides business addresses worldwide by geographical areas and by standard industrial classification (SIC) codes. Maps Map Catalog (New York, Tilden...Francisco. These offices are often excellent sources of free printed matter — brochures, maps, posters, etc. A directory of tourism offices worldwide is...Peterson’s Guides, Inc.). Published irregularly, these sources offer information by field of work (agriculture, business and industry , teaching English

From Planetary Mapping to Map Production: Planetary Cartography as integral discipline in Planetary Sciences

NASA Astrophysics Data System (ADS)

Nass, Andrea; van Gasselt, Stephan; Hargitai, Hendrik; Hare, Trent; Manaud, Nicolas; Karachevtseva, Irina; Kersten, Elke; Roatsch, Thomas; Wählisch, Marita; Kereszturi, Akos

2016-04-01

Cartography is one of the most important communication channels between users of spatial information and laymen as well as the open public alike. This applies to all known real-world objects located either here on Earth or on any other object in our Solar System. In planetary sciences, however, the main use of cartography resides in a concept called planetary mapping with all its various attached meanings: it can be (1) systematic spacecraft observation from orbit, i.e. the retrieval of physical information, (2) the interpretation of discrete planetary surface units and their abstraction, or it can be (3) planetary cartography sensu strictu, i.e., the technical and artistic creation of map products. As the concept of planetary mapping covers a wide range of different information and knowledge levels, aims associated with the concept of mapping consequently range from a technical and engineering focus to a scientific distillation process. Among others, scientific centers focusing on planetary cartography are the United State Geological Survey (USGS, Flagstaff), the Moscow State University of Geodesy and Cartography (MIIGAiK, Moscow), Eötvös Loránd University (ELTE, Hungary), and the German Aerospace Center (DLR, Berlin). The International Astronomical Union (IAU), the Commission Planetary Cartography within International Cartographic Association (ICA), the Open Geospatial Consortium (OGC), the WG IV/8 Planetary Mapping and Spatial Databases within International Society for Photogrammetry and Remote Sensing (ISPRS) and a range of other institutions contribute on definition frameworks in planetary cartography. Classical cartography is nowadays often (mis-)understood as a tool mainly rather than a scientific discipline and an art of communication. Consequently, concepts of information systems, mapping tools and cartographic frameworks are used interchangeably, and cartographic workflows and visualization of spatial information in thematic maps have often been neglected or were left to software systems to decide by some arbitrary default values. The diversity of cartography as a research discipline and its different contributions in geospatial sciences and communication of information and knowledge will be highlighted in this contribution. We invite colleagues from this and other discipline to discuss concepts and topics for joint future collaboration and research.

The International Permafrost Association: new structure and initiatives for cryospheric research

NASA Astrophysics Data System (ADS)

May, I.; Lewkowicz, A. G.; Christiansen, H.; Romanovsky, V. E.; Lantuit, H.; Schrott, L.; Sergeev, D.; Wei, M.

2012-12-01

The International Permafrost Association (IPA), founded in 1983, has as its objectives to foster the dissemination of knowledge concerning permafrost and to promote cooperation among persons and national or international organizations engaged in scientific investigation and engineering work on permafrost. The IPA's primary responsibilities are convening International Permafrost Conferences, undertaking special projects such as preparing databases, maps, bibliographies, and glossaries, and coordinating international field programs and networks. Membership is through adhering national or multinational organizations or as individuals in countries where no Adhering Body exists. The IPA is governed by its Executive Committee and a Council consisting of representatives from 26 Adhering Bodies having interests in some aspect of theoretical, basic and applied frozen ground research, including permafrost, seasonal frost, artificial freezing and periglacial phenomena. This presentation details recent and ongoing changes in the functioning of the IPA that will influence the way cryospheric research is conducted under its auspices. One of the most important is the development of competitively-funded Action Groups which work towards the production of well-defined products over a period of two years. Since the first call, four proposals have been accepted by the Executive Committee and the teams are currently working on high topical issues, such as the assessment of the deep permafrost organic carbon pools and the mapping of subsea permafrost, as well as fundamental questions such as the extent of permafrost during the Last Permafrost Maximum. The IPA also decided to put additional effort into facilitating the study of the significance of permafrost to the global climate systems, with human aspects playing a very important role. To achieve this goal, the IPA will encourage and assist the climate modeling community in improving the representation of perennially frozen ground within Global Climate Models and promote the study of the carbon cycle and other biogeochemical cycles in permafrost regions that contribute to atmospheric greenhouse gas concentrations. Within the discussion of climate change and the organic carbon stored in the frozen ground, the IPA also fosters and supports the activities of the Global Terrestrial Network on Permafrost (GTN-P) sponsored by the Global Terrestrial Observing System, GTOS, and the Global Climate Observing System, GCOS, whose long-term goal is to obtain a comprehensive view of the spatial structure, trends, and variability of changes in the active layer thickness and permafrost temperature. A further important initiative of the IPA is the new Standing Committee on Outreach and Education that is responsible for the development and implementation of new outreach products and projects on permafrost for schools, universities, and the general public. In all of these activities, the IPA emphasizes the involvement of young researchers (especially through the Permafrost Young Researchers Network) as well as its international partner organizations.

Geologic map of the Jasper Quadrangle, Newton and Boone counties, Arkansas

USGS Publications Warehouse

Hudson, M.R.; Murray, K.E.; Pezzutti, Deborah

2001-01-01

This digital geologic map compilation presents new polygon (i.e., geologic map unit contacts), line (i.e., fault, fold axis, and structure contour), and point (i.e., structural attitude, contact elevations) vector data for the Jasper 7 1/2' quadrangle in northern Arkansas. The map database, which is at 1:24,000-scale resolution, provides geologic coverage of an area of current hydrogeologic, tectonic, and stratigraphic interest. The Jasper quadrangle is located in northern Newton and southern Boone Counties about 20 km south of the town of Harrison. The map area is underlain by sedimentary rocks of Ordovician, Mississippian, and Pennsylvanian age that were mildly deformed by a series of normal and strike-slip faults and folds. The area is representative of the stratigraphic and structural setting of the southern Ozark Dome. The Jasper quadrangle map provides new geologic information for better understanding groundwater flow paths in and adjacent to the Buffalo River watershed.

Geologic map of the Hasty Quadrangle, Boone and Newton Counties, Arkansas

USGS Publications Warehouse

Hudson, Mark R.; Murray, Kyle E.

2004-01-01

This digital geologic map compilation presents new polygon (for example, geologic map unit contacts), line (for example, fault, fold axis, and structure contour), and point (for example, structural attitude, contact elevations) vector data for the Hasty 7.5-minute quadrangle in northern Arkansas. The map database, which is at 1:24,000-scale resolution, provides geologic coverage of an area of current hydrogeologic, tectonic, and stratigraphic interest. The Hasty quadrangle is located in northern Newton and southern Boone Counties about 20 km south of the town of Harrison. The map area is underlain by sedimentary rocks of Ordovician, Mississippian, and Pennsylvanian age that were mildly deformed by a series of normal and strike-slip faults and folds. The area is representative of the stratigraphic and structural setting of the southern Ozark Dome. The Hasty quadrangle map provides new geologic information for better understanding groundwater flow paths in and adjacent to the Buffalo River watershed.

Research and Practice of the News Map Compilation Service

NASA Astrophysics Data System (ADS)

Zhao, T.; Liu, W.; Ma, W.

2018-04-01

Based on the needs of the news media on the map, this paper researches on the news map compilation service, conducts demand research on the service of compiling news maps, designs and compiles the public authority base map suitable for media publication, and constructs the news base map material library. It studies the compilation of domestic and international news maps with timeliness and strong pertinence and cross-regional characteristics, constructs the hot news thematic gallery and news map customization services, conducts research on types of news maps, establish closer liaison and cooperation methods with news media, and guides news media to use correct maps. Through the practice of the news map compilation service, this paper lists two cases of news map preparation services used by different media, compares and analyses cases, summarizes the research situation of news map compilation service, and at the same time puts forward outstanding problems and development suggestions in the service of news map compilation service.

Exploring the Interconnected Trauma of Personal, Social, and Structural Stressors: Making "Sense" of Senseless Violence.

PubMed

Abo-Zena, Mona M

2017-01-02

Although violence is a timeless characteristic of human behavior and history, its prevalence and many forms are proliferated repeatedly through the media. In particular, "senseless" violence against both random and targeted victims puzzles and petrifies onlookers and survivors. Integrating developmental psychology with critical theory, this manuscript begins with a conceptual definition of senseless violence that is coupled with a mapping of the personal, social, and structural etiologies of such violence. This inquiry explores the origins, contexts, and varied manifestations of violence, helps redirect sense-making around such violence, and informs how to cope with and possibly reduce or mitigate it. Utilizing a person-centered perspective from multiple points of view, the analysis focuses primarily on the everyday or chronic experiences of stressors and their relation to internalized and externalized types of violence (i.e., mass shootings, interpersonal violence, self-injury). The manuscript concludes with ways to reduce violence and promote justice on personal, social, and structural levels.

Structural basis for DNA binding by replication initiator Mcm10

DOE Office of Scientific and Technical Information (OSTI.GOV)

Warren, Eric M.; Vaithiyalingam, Sivaraja; Haworth, Justin

2009-06-30

Mcm10 is an essential eukaryotic DNA replication protein required for assembly and progression of the replication fork. The highly conserved internal domain (Mcm10-ID) has been shown to physically interact with single-stranded (ss) DNA, DNA polymerase alpha, and proliferating cell nuclear antigen (PCNA). The crystal structure of Xenopus laevis Mcm10-ID presented here reveals a DNA binding architecture composed of an oligonucleotide/oligosaccharide-fold followed in tandem by a variant and highly basic zinc finger. NMR chemical shift perturbation and mutational studies of DNA binding activity in vitro reveal how Mcm10 uses this unique surface to engage ssDNA. Corresponding mutations in Saccharomyces cerevisiae resultmore » in increased sensitivity to replication stress, demonstrating the functional importance of DNA binding by this region of Mcm10 to replication. In addition, mapping Mcm10 mutations known to disrupt PCNA, polymerase alpha, and DNA interactions onto the crystal structure provides insight into how Mcm10 might coordinate protein and DNA binding within the replisome.« less

Mapping transiently formed and sparsely populated conformations on a complex energy landscape

PubMed Central

Wang, Yong; Papaleo, Elena; Lindorff-Larsen, Kresten

2016-01-01

Determining the structures, kinetics, thermodynamics and mechanisms that underlie conformational exchange processes in proteins remains extremely difficult. Only in favourable cases is it possible to provide atomic-level descriptions of sparsely populated and transiently formed alternative conformations. Here we benchmark the ability of enhanced-sampling molecular dynamics simulations to determine the free energy landscape of the L99A cavity mutant of T4 lysozyme. We find that the simulations capture key properties previously measured by NMR relaxation dispersion methods including the structure of a minor conformation, the kinetics and thermodynamics of conformational exchange, and the effect of mutations. We discover a new tunnel that involves the transient exposure towards the solvent of an internal cavity, and show it to be relevant for ligand escape. Together, our results provide a comprehensive view of the structural landscape of a protein, and point forward to studies of conformational exchange in systems that are less characterized experimentally. DOI: http://dx.doi.org/10.7554/eLife.17505.001 PMID:27552057

Correlative live and super-resolution imaging reveals the dynamic structure of replication domains.

PubMed

Xiang, Wanqing; Roberti, M Julia; Hériché, Jean-Karim; Huet, Sébastien; Alexander, Stephanie; Ellenberg, Jan

2018-06-04

Chromosome organization in higher eukaryotes controls gene expression, DNA replication, and DNA repair. Genome mapping has revealed the functional units of chromatin at the submegabase scale as self-interacting regions called topologically associating domains (TADs) and showed they correspond to replication domains (RDs). A quantitative structural and dynamic description of RD behavior in the nucleus is, however, missing because visualization of dynamic subdiffraction-sized RDs remains challenging. Using fluorescence labeling of RDs combined with correlative live and super-resolution microscopy in situ, we determined biophysical parameters to characterize the internal organization, spacing, and mechanical coupling of RDs. We found that RDs are typically 150 nm in size and contain four co-replicating regions spaced 60 nm apart. Spatially neighboring RDs are spaced 300 nm apart and connected by highly flexible linker regions that couple their motion only <550 nm. Our pipeline allows a robust quantitative characterization of chromosome structure in situ and provides important biophysical parameters to understand general principles of chromatin organization. © 2018 Xiang et al.

Structure-based design, synthesis, and biological evaluation of imidazo[1,2-b]pyridazine-based p38 MAP kinase inhibitors.

PubMed

Kaieda, Akira; Takahashi, Masashi; Takai, Takafumi; Goto, Masayuki; Miyazaki, Takahiro; Hori, Yuri; Unno, Satoko; Kawamoto, Tomohiro; Tanaka, Toshimasa; Itono, Sachiko; Takagi, Terufumi; Hamada, Teruki; Shirasaki, Mikio; Okada, Kengo; Snell, Gyorgy; Bragstad, Ken; Sang, Bi-Ching; Uchikawa, Osamu; Miwatashi, Seiji

2018-02-01

We identified novel potent inhibitors of p38 MAP kinase using structure-based design strategy. X-ray crystallography showed that when p38 MAP kinase is complexed with TAK-715 (1) in a co-crystal structure, Phe169 adopts two conformations, where one interacts with 1 and the other shows no interaction with 1. Our structure-based design strategy shows that these two conformations converge into one via enhanced protein-ligand hydrophobic interactions. According to the strategy, we focused on scaffold transformation to identify imidazo[1,2-b]pyridazine derivatives as potent inhibitors of p38 MAP kinase. Among the herein described and evaluated compounds, N-oxide 16 exhibited potent inhibition of p38 MAP kinase and LPS-induced TNF-α production in human monocytic THP-1 cells, and significant in vivo efficacy in rat collagen-induced arthritis models. In this article, we report the discovery of potent, selective and orally bioavailable imidazo[1,2-b]pyridazine-based p38 MAP kinase inhibitors with pyridine N-oxide group. Copyright © 2018 Elsevier Ltd. All rights reserved.

GIS applications for military operations in coastal zones

USGS Publications Warehouse

Fleming, S.; Jordan, T.; Madden, M.; Usery, E.L.; Welch, R.

2009-01-01

In order to successfully support current and future US military operations in coastal zones, geospatial information must be rapidly integrated and analyzed to meet ongoing force structure evolution and new mission directives. Coastal zones in a military-operational environment are complex regions that include sea, land and air features that demand high-volume databases of extreme detail within relatively narrow geographic corridors. Static products in the form of analog maps at varying scales traditionally have been used by military commanders and their operational planners. The rapidly changing battlefield of 21st Century warfare, however, demands dynamic mapping solutions. Commercial geographic information system (GIS) software for military-specific applications is now being developed and employed with digital databases to provide customized digital maps of variable scale, content and symbolization tailored to unique demands of military units. Research conducted by the Center for Remote Sensing and Mapping Science at the University of Georgia demonstrated the utility of GIS-based analysis and digital map creation when developing large-scale (1:10,000) products from littoral warfare databases. The methodology employed-selection of data sources (including high resolution commercial images and Lidar), establishment of analysis/modeling parameters, conduct of vehicle mobility analysis, development of models and generation of products (such as a continuous sea-land DEM and geo-visualization of changing shorelines with tidal levels)-is discussed. Based on observations and identified needs from the National Geospatial-Intelligence Agency, formerly the National Imagery and Mapping Agency, and the Department of Defense, prototype GIS models for military operations in sea, land and air environments were created from multiple data sets of a study area at US Marine Corps Base Camp Lejeune, North Carolina. Results of these models, along with methodologies for developing large-scale littoral warfare databases, aid the National Geospatial-Intelligence Agency in meeting littoral warfare analysis, modeling and map generation requirements for US military organizations. ?? 2008 International Society for Photogrammetry and Remote Sensing, Inc. (ISPRS).

Shaded relief aeromagnetic map of the Santa Clara Valley and vicinity, California

USGS Publications Warehouse

Roberts, Carter W.; Jachens, Robert C.

2003-01-01

This aeromagnetic map covers the southern portion of San Francisco Bay, the Santa Clara Valley and surrounding mountains, part of which has been modelled in threedimensions (Jachens and other, 2001). The magnetic anomaly map has been compiled from existing digital data. Data was obtained from six aeromagnetic surveys that were flown at different times, spacings and elevations. The International Geomagnetic Reference Field (IGRF) for the date of each survey had been removed in the initial processing. The resulting residual magnetic anomalies were analytically continued onto a common surface 305 m (1000 ft) above terrain. Portions of each survey were substantially above the specified flight height listed in the table. The surveys were then merged together using a commercial software package called Oasis Montage. The gray lines on the map indicate the extent of each survey. The program used these regions of overlap to determine the best fit between surveys. Black dots show probable edges of magnetic bodies defined by the maximum horizontal gradient determined using a computer program by Blakely (1995). Crystalline rocks generally contain sufficient magnetic minerals to cause variations in the Earth’s magnetic field that can be mapped by aeromagnetic surveys. Sedimentary rocks are generally weakly magnetized and consequently have a small effect on the magnetic field: thus a magnetic anomaly map can be used to “see through” the sedimentary rock cover and can convey information on lithologic contrasts and structural trends related to the underlying crystalline basement (see Nettleton,1971; Blakely, 1995). Faults often cut magnetic bodies and offset magnetic anomalies can thus be used to help determine fault motion. Serpentinite, which is highly magnetic, is often found along faults. On this map areas of low magnetic anomalies are shown in blues and green while highs are shown in reds and magentas. Faults are from Brabb and others, 1998a,1998b, Graymer and others 1996, Lienkaemper, 1992 and Wentworth and others 1998.

The Structure of Medical Informatics Journal Literature

PubMed Central

Morris, Theodore A.; McCain, Katherine W.

1998-01-01

Abstract Objective: Medical informatics is an emergent interdisciplinary field described as drawing upon and contributing to both the health sciences and information sciences. The authors elucidate the disciplinary nature and internal structure of the field. Design: To better understand the field's disciplinary nature, the authors examine the intercitation relationships of its journal literature. To determine its internal structure, they examined its journal cocitation patterns. Measurements: The authors used data from the Science Citation Index (SCI) and Social Science Citation Index (SSCI) to perform intercitation studies among productive journal titles, and software routines from SPSS to perform multivariate data analyses on cocitation data for proposed core journals. Results: Intercitation network analysis suggests that a core literature exists, one mark of a separate discipline. Multivariate analyses of cocitation data suggest that major focus areas within the field include biomedical engineering, biomedical computing, decision support, and education. The interpretable dimensions of multidimensional scaling maps differed for the SCI and SSCI data sets. Strong links to information science literature were not found. Conclusion: The authors saw indications of a core literature and of several major research fronts. The field appears to be viewed differently by authors writing in journals indexed by SCI from those writing in journals indexed by SSCI, with more emphasis placed on computers and engineering versus decision making by the former and more emphasis on theory versus application (clinical practice) by the latter. PMID:9760393

Analysis of laser radar measurements of the asteroid 433 Eros

NASA Astrophysics Data System (ADS)

Cole, Timothy D.; Zuber, Maria T.; Neuman, Greg; Cheng, Andrew F.; Reiter, R. Alan; Guo, Yanping; Smith, David E.

2001-09-01

After a 5-year mission, a 4-year transit followed by a one-year mission orbiting the asteroid 433 Eros, the Near-Earth Asteroid Rendezvous-Shoemaker (NEAR) spacecraft made a controlled landing onto the asteroid's surface on 12 February 2001. Onboard the spacecraft, the NEAR Laser Rangefinder (NLR) facility instrument had gathered over 11 million measurements, providing a spatially dense, high-resolution, topographical map of Eros. This topographic data, combined with Doppler tracking data for the spacecraft, enabled the determination of the asteroid's shape, mass, and density thereby contributing to understanding the internal structure and collisional evolution of Eros. NLR data indicate that Eros is a consolidated body with a complex shape dominated by collisions. The offset between the asteroid's center of mass and center of figure indicates a small deviation from a homogeneous internal structure that is most simply explained by variations in mechanical structure. Regional-scale relief and slope distributions show evidence for control of some topography by a competent substrate. It was found that pulse dilation was the major source of uncertainty in single-shot range measurements from the NLR, and that this uncertainty remains consistent with the overall 6-m range measurement system accuracy for NEAR. Analysis of NLR data fully quantified the geodynamic nature of this planetesimal, ergo, illustrating the utility of laser altimetry for remote sensing.

The Seismotectonic Map of Africa

NASA Astrophysics Data System (ADS)

Meghraoui, Mustapha

2015-04-01

We present the Seismotectonic Map of Africa based on a geological, geophysical and geodetic database including the instrumental seismicity and re-appraisal of large historical events with harmonization and homogenization of earthquake parameters in catalogues. Although the seismotectonic framework and mapping of the African continent is a difficult task, several previous and ongoing projects provide a wealth of data and outstanding results. The database of large and moderate earthquakes in different geological domains includes the coseismic and Quaternary faulting that reveals the complex nature of the active tectonics in Africa. The map also benefits from previous works on local and regional seismotectonic maps that needed to be integrated with the lithospheric and upper mantle structures from tomographic anisotropy and gravity anomaly into a continental framework. The synthesis of earthquake and volcanic studies with the analysis of long-term (late Quaternary) and short-term (last decades and centuries) active deformation observed with geodetic and other approaches presented along with the seismotectonic map serves as a basis for hazard calculations and the reduction of seismic risks. The map may also be very useful in the assessment of seismic hazard and mitigation of earthquake risk for significant infrastructures and their implications in the socio-economic impact in Africa. In addition, the constant population increase and infrastructure growth in the continent that exacerbate the earthquake risk justify the necessity for a continuous updating of the seismotectonic map. The database and related map are prepared in the framework of the IGC Project-601 "Seismotectonics and Seismic Hazards in Africa" of UNESCO-IUGS, funded by the Swedish International Development Agency and UNESCO-Nairobi for a period of 4 years (2011 - 2014), extended to 2016. * Mustapha Meghraoui (Coordinator) EOST - IPG Strasbourg CNRS-UMR 7516 m.meghraoui@unistra.fr corresponding author. Paulina Amponsah (AECG, Accra), Abdelhakim Ayadi (CRAAG, Algiers), Atalay Ayele (Univ. Addis Ababa), Ateba Bekoa (Bueah Univ. Yaounde), Abdunnur Bensuleman (Tripoli Univ.), Damien Delvaux (MRAC-Tervuren); Mohamed El Gabry (NRIAG, Cairo), Rui-Manuel Fernandes (Beira Univ.) ; Vunganai Midzi & Magda Roos (CGS, Pretoria), Youssef Timoulali (Univ. Mohamed V, Rabat). Website: http://eost.u-strasbg.fr/igcp601/index.html

Preliminary metallogenic belt and mineral deposit maps for northeast Asia

USGS Publications Warehouse

Obolenskiy, Alexander A.; Rodionov, Sergey M.; Dejidmaa, Gunchin; Gerel, Ochir; Hwang, Duk-Hwan; Distanov, Elimir G.; Badarch, Gombosuren; Khanchuk, Alexander I.; Ogasawara, Masatsugu; Nokleberg, Warren J.; Parfenov, Leonid M.; Prokopiev, Andrei V.; Seminskiy, Zhan V.; Smelov, Alexander P.; Yan, Hongquan; Birul'kin, Gennandiy V.; Davydov, Yuriy V.V.; Fridovskiy, Valeriy Yu.; Gamyanin, Gennandiy N.; Kostin, Alexei V.; Letunov, Sergey A.; Li, Xujun; Nikitin, Valeriy M.; Sotnikov, Sadahisa; Sudo, Vitaly I.; Spiridonov, Alexander V.; Stepanov, Vitaly A.; Sun, Fengyue; Sun, Jiapeng; Sun, Weizhi; Supletsov, Valeriy M.; Timofeev, Vladimir F.; Tyan, Oleg A.; Vetluzhskikh, Valeriy G.; Wakita, Koji; Yakovlev, Yakov V.; Zorina, Lydia M.

2003-01-01

The metallogenic belts and locations of major mineral deposits of Northeast Asia are portrayed on Sheets 1-4. Sheet 1 portrays the location of significant lode deposits and placer districts at a scale of 1:7,500,000. Sheets 2-4 portray the metallogenic belts of the region in a series of 12 time-slices from the Archean through the Quaternary at a scale of 1:15,000,000. For all four map sheets, a generalized geodynamics base map, derived from a more detailed map by Parfenov and others (2003), is used as an underlay for the metallogenic belt maps. This geodynamics map underlay permits depicts the major host geologic units and structures that host metallogenic belts. Four tables are included in this report. A hierarchial ranking of mineral deposit models is listed in Table 1. And summary features of lode deposits, placer districts, and metallogenic belts are described in Tables 2, 3, and 4, respectively. The metallogenic belts for Northeast Asia are synthesized, compiled, described, and interpreted with the use of modern concepts of plate tectonics, analysis of terranes and overlap assemblages, and synthesis of mineral deposit models. The data supporting the compilation are: (1) comprehensive descriptions of mineral deposits; (2) compilation and synthesis of a regional geodynamics map the region at 5 million scale with detailed explanations and cited references; and (3) compilation and synthesis of metallogenic belt maps at 15 million scale with detailed explanations and cited references. These studies are part of a major international collaborative study of the Mineral Resources, Metallogenesis, and Tectonics of Northeast Asia that is being conducted from 1997 through 2002 by geologists from earth science agencies and universities in Russia, Mongolia, Northeastern China, South Korea, Japan, and the USA. Companion studies and previous publications are: (1) a detailed geodynamics map of Northeast Asia (Parfenov and 2003); (2) a compilation of major mineral deposit models (Rodionov and Nokleberg, 2000; Rodionov and others, 2000; Obolenskiy and others, 2003); and (3) a database on significant metalliferous and selected nonmetalliferous lode deposits, and selected placer districts (Ariunbileg and others, 2003).

Remote sensing-based landscape indicators for the evaluation of threatened-bird habitats in a tropical forest.

PubMed

Singh, Minerva; Tokola, Timo; Hou, Zhengyang; Notarnicola, Claudia

2017-07-01

Avian species persistence in a forest patch is strongly related to the degree of isolation and size of a forest patch and the vegetation structure within a patch and its matrix are important predictors of bird habitat suitability. A combination of space-borne optical (Landsat), ALOS-PALSAR (radar), and airborne Light Detection and Ranging (LiDAR) data was used for assessing variation in forest structure across forest patches that had undergone different levels of forest degradation in a logged forest-agricultural landscape in Southern Laos. The efficacy of different remote sensing (RS) data sources in distinguishing forest patches that had different seizes, configurations, and vegetation structure was examined. These data were found to be sensitive to the varying levels of degradation of the different patch categories. Additionally, the role of local scale forest structure variables (characterized using the different RS data and patch area) and landscape variables (characterized by distance from different forest patches) in influencing habitat preferences of International Union for Conservation of Nature (IUCN) Red listed birds found in the study area was examined. A machine learning algorithm, MaxEnt, was used in conjunction with these data and field collected geographical locations of the avian species to identify the factors influencing habitat preference of the different bird species and their suitable habitats. Results show that distance from different forest patches played a more important role in influencing habitat suitability for the different avian species than local scale factors related to vegetation structure and health. In addition to distance from forest patches, LiDAR-derived forest structure and Landsat-derived spectral variables were important determinants of avian habitat preference. The models derived using MaxEnt were used to create an overall habitat suitability map (HSM) which mapped the most suitable habitat patches for sustaining all the avian species. This work also provides insight that retention of forest patches, including degraded and isolated forest patches in addition to large contiguous forest patches, can facilitate bird species retention within tropical agricultural landscapes. It also demonstrates the effective use of RS data in distinguishing between forests that have undergone varying levels of degradation and identifying the habitat preferences of different bird species. Practical conservation management planning endeavors can use such data for both landscape scale monitoring and habitat mapping.

HYTHIRM Radiance Modeling and Image Analyses in Support of STS-119, STS-125 and STS-128 Space Shuttle Hypersonic Re-entries

NASA Technical Reports Server (NTRS)

Gibson, David M.; Spisz, Thomas S.; Taylor, Jeff C.; Zalameda, Joseph N.; Horvath, Thomas J.; Tomek, Deborah M.; Tietjen, Alan B.; Tack, Steve; Bush, Brett C.

2010-01-01

We provide the first geometrically accurate (i.e., 3-D) temperature maps of the entire windward surface of the Space Shuttle during hypersonic reentry. To accomplish this task we began with estimated surface temperatures derived from CFD models at integral high Mach numbers and used them, the Shuttle's surface properties and reasonable estimates of the sensor-to-target geometry to predict the emitted spectral radiance from the surface (in units of W sr-1 m-2 nm-1). These data were converted to sensor counts using properties of the sensor (e.g. aperture, spectral band, and various efficiencies), the expected background, and the atmosphere transmission to inform the optimal settings for the near-infrared and midwave IR cameras on the Cast Glance aircraft. Once these data were collected, calibrated, edited, registered and co-added we formed both 2-D maps of the scene in the above units and 3-D maps of the bottom surface in temperature that could be compared with not only the initial inputs but also thermocouple data from the Shuttle itself. The 3-D temperature mapping process was based on the initial radiance modeling process. Here temperatures were guessed for each node in a well-resolved 3-D framework, a radiance model was produced and compared to the processed imagery, and corrections to the temperature were estimated until the iterative process converged. This process did very well in characterizing the temperature structure of the large asymmetric boundary layer transition the covered much of the starboard bottom surface of STS-119 Discovery. Both internally estimated accuracies and differences with CFD models and thermocouple measurements are at most a few percent. The technique did less well characterizing the temperature structure of the turbulent wedge behind the trip due to limitations in understanding the true sensor resolution. (Note: Those less inclined to read the entire paper are encouraged to read an Executive Summary provided at the end.)

Understanding the role of contrasting urban contexts in healthy aging: an international cohort study using wearable sensor devices (the CURHA study protocol).

PubMed

Kestens, Yan; Chaix, Basile; Gerber, Philippe; Desprès, Michel; Gauvin, Lise; Klein, Olivier; Klein, Sylvain; Köppen, Bernhard; Lord, Sébastien; Naud, Alexandre; Payette, Hélène; Richard, Lucie; Rondier, Pierre; Shareck, Martine; Sueur, Cédric; Thierry, Benoit; Vallée, Julie; Wasfi, Rania

2016-05-05

Given the challenges of aging populations, calls have been issued for more sustainable urban re-development and implementation of local solutions to address global environmental and healthy aging issues. However, few studies have considered older adults' daily mobility to better understand how local built and social environments may contribute to healthy aging. Meanwhile, wearable sensors and interactive map-based applications offer novel means for gathering information on people's mobility, levels of physical activity, or social network structure. Combining such data with classical questionnaires on well-being, physical activity, perceived environments and qualitative assessment of experience of places opens new opportunities to assess the complex interplay between individuals and environments. In line with current gaps and novel analytical capabilities, this research proposes an international research agenda to collect and analyse detailed data on daily mobility, social networks and health outcomes among older adults using interactive web-based questionnaires and wearable sensors. Our study resorts to a battery of innovative data collection methods including use of a novel multisensor device for collection of location and physical activity, interactive map-based questionnaires on regular destinations and social networks, and qualitative assessment of experience of places. This rich data will allow advanced quantitative and qualitative analyses in the aim to disentangle the complex people-environment interactions linking urban local contexts to healthy aging, with a focus on active living, social networks and participation, and well-being. This project will generate evidence about what characteristics of urban environments relate to active mobility, social participation, and well-being, three important dimensions of healthy aging. It also sets the basis for an international research agenda on built environment and healthy aging based on a shared and comprehensive data collection protocol.

The Tin Bider Impact Structure, Algeria: New Map with Field Inputs on Structural Aspect

NASA Astrophysics Data System (ADS)

Kassab, F.; Belhai, D.

2017-07-01

The Tin Bider impact structure is a complex type composed by sedimentary target rocks. We realized a geological map including new inputs on impact characters of a recent field investigation where we identify shatter cone and folds.

Maps showing geology, structure, and geophysics of the central Black Hills, South Dakota

USGS Publications Warehouse

Redden, Jack A.; DeWitt, Ed

2008-01-01

This 1:100,000-scale digital geologic map details the complex Early Proterozoic granitic rocks, Early Proterozoic supracrustal metamorphic rocks, and Archean crystalline basement of the Black Hills. The granitic rocks host pegmatite deposits renowned for their feldspar, mica, spodumene, and beryl. The supracrustal rocks host the Homestake gold mine, which produced more than 40 million ounces of gold over a 125-year lifetime. The map documents the Laramide deformation of Paleozoic and Mesozoic cover rocks; and shows the distribution of Laramide plutonic rocks associated with precious-metals deposits. Four 1:300,000-scale maps summarize Laramide structures; Early Proterozoic structures; aeromagnetic anomalies; and gravity anomalies. Three 1:500,000-scale maps show geophysical interpretations of buried Early Proterozoic to Archean rocks in western South Dakota and eastern Wyoming.