Cocoa bean quality assessment by using hyperspectral images and fuzzy logic techniques

NASA Astrophysics Data System (ADS)

Soto, Juan; Granda, Guillermo; Prieto, Flavio; Ipanaque, William; Machacuay, Jorge

2015-04-01

Nowadays, cocoa bean exportation from Piura-Peru is having a positive international market response due to their inherent high quality. Nevertheless, when using subjective techniques for quality assessment, such as the cut test, a wastefulness of grains is generated, additional to a restriction in the selection as well as improvement approaches in earlier stages for optimizing the quality. Thus, in an attempt to standardize the internal features analyzed by the cut test, for instance, crack formation and internal color changes during the fermentation, this research is submitted as an approach which aims to make use of hyperspectral images, with the purpose of having a quick and accurate analysis. Hyperspectral cube size was reduced by using Principal Component Analysis (PCA). The image generated by principal component PC1 provides enough information to clearly distinguish the internal cracks of the cocoa bean, since the zones where these cracks are, have a negative correlation with PC1. The features taken were processed through a fuzzy block, which is able to describe the cocoa bean quality. Three membership functions were defined in the output: unfermented, partly fermented and well fermented, by using trapezoidal-shaped and triangular-shaped functions. A total of twelve rules were propounded. Furthermore, the bisector method was chosen for the defuzzification. Begin the abstract two lines below author names and addresses.

Planning activity for internally generated reward goals in monkey amygdala neurons

PubMed Central

Schultz, Wolfram

2015-01-01

The best rewards are often distant and can only be achieved by planning and decision-making over several steps. We designed a multi-step choice task in which monkeys followed internal plans to save rewards towards self-defined goals. During this self-controlled behavior, amygdala neurons showed future-oriented activity that reflected the animal’s plan to obtain specific rewards several trials ahead. This prospective activity encoded crucial components of the animal’s plan, including value and length of the planned choice sequence. It began on initial trials when a plan would be formed, reappeared step-by-step until reward receipt, and readily updated with a new sequence. It predicted performance, including errors, and typically disappeared during instructed behavior. Such prospective activity could underlie the formation and pursuit of internal plans characteristic for goal-directed behavior. The existence of neuronal planning activity in the amygdala suggests an important role for this structure in guiding behavior towards internally generated, distant goals. PMID:25622146

Characterizing and Modeling the Cost of Rework in a Library of Reusable Software Components

NASA Technical Reports Server (NTRS)

Basili, Victor R.; Condon, Steven E.; ElEmam, Khaled; Hendrick, Robert B.; Melo, Walcelio

1997-01-01

In this paper we characterize and model the cost of rework in a Component Factory (CF) organization. A CF is responsible for developing and packaging reusable software components. Data was collected on corrective maintenance activities for the Generalized Support Software reuse asset library located at the Flight Dynamics Division of NASA's GSFC. We then constructed a predictive model of the cost of rework using the C4.5 system for generating a logical classification model. The predictor variables for the model are measures of internal software product attributes. The model demonstrates good prediction accuracy, and can be used by managers to allocate resources for corrective maintenance activities. Furthermore, we used the model to generate proscriptive coding guidelines to improve programming, practices so that the cost of rework can be reduced in the future. The general approach we have used is applicable to other environments.

International Test Program for Synergistic Atomic Oxygen and VUV Exposure of Spacecraft Materials

NASA Technical Reports Server (NTRS)

Rutledge, Sharon; Banks, Bruce; Dever, Joyce; Savage, William

2000-01-01

Spacecraft in low Earth orbit (LEO) are subject to degradation in thermal and optical performance of components and materials through interaction with atomic oxygen and vacuum ultraviolet radiation which are predominant in LEO. Due to the importance of LEO durability and performance to manufacturers and users, an international test program for assessing the durability of spacecraft materials and components was initiated. Initial tests consisted of exposure of samples representing a variety of thermal control paints and multilayer insulation materials that have been used in space. Materials donated from various international sources were tested alongside a material whose performance is well known such as Teflon FEP or Kapton H for multilayer insulation, or Z-93-P for white thermal control paints. The optical, thermal or mass loss data generated during the test was then provided to the participating material supplier. Data was not published unless the participant donating the material consented to publication. This paper presents a description of the types of tests and facilities that have been used for the test program as well as some examples of data that have been generated. The test program is intended to give spacecraft builders and users a better understanding of degradation processes and effects to enable improved prediction of spacecraft performance.

Innovation and Idea Flow at U.S. International Campuses

ERIC Educational Resources Information Center

Martin, Justin D.

2014-01-01

This article explores some of the components of innovation that U.S. universities abroad can seize, or in some cases have seized, upon to maximize information flow, productivity, and idea generation at their overseas institutions. Using research in psychology, education, economics, and other fields, the article identifies the following as among…

Analysis of On-Board Oxygen and Nitrogen Generation Systems for Surface Vessels.

DTIC Science & Technology

1983-06-01

and Pressure Vessel Code SAE AIR 822 Oxygen for General Aviation Aircraft SAE AIR 825 Oxygen for Aircrafts SAE AIR 1059 Transportation and Maintenance...OF THE TITLE MIL-T-27730 Threaded Components MIL-P-27401 A 40 Micron Filter For Nitrogen MIL-V-33650 Internal Straight Threads ASME Code VIII Boiler

A novel method for determining the phase-noise behavior of resonator-oscillators

NASA Astrophysics Data System (ADS)

Hoffmann, Michael H. W.

2005-05-01

A novel approach to the theory of phase-noise in resonator-oscillators will be given that is based on a combination of a large-signal-small-signal method, harmonic balance, and a modified Rice-model of signals plus noise. The method will be explained using a simple example. Since the type of oscillator under consideration not only de-attenuates eigen-oscillations but also noise in the spectral vicinity of the eigen-frequency, a signal is generated that is quasi-harmonic, and that might be described by means of a pseudo-Fourier-series expansion. Due to the specific description of the internal noise-sources, it is possible to use a time-domain description that at the same time reveals information about the spectral components of the signal. By comparison of these components, the spectrum of the oscillation might be determined. Relations between the spectrum of internal noise sources and the generated oscillator-signal will be recognized. The novel method will thus enable the designer to predict the phase-noise behavior of a specific oscillator-design.

MIS High-Purity Plutonium Oxide Hydride Product 5501579 (SSR124): Final Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Veirs, Douglas Kirk; Stroud, Mary Ann; Berg, John M.

A high-purity plutonium dioxide material from the Material Identification and Surveillance (MIS) Program inventory has been studied with regard to gas generation and corrosion in a storage environment. Sample 5501579 represents process plutonium oxides from hydride oxide from Rocky Flats that are currently stored in 3013 containers. After calcination to 950°C, the material contained 87.42% plutonium with no major impurities. This study followed over time, the gas pressure of a sample with nominally 0.5 wt% water in a sealed container with an internal volume scaled to 1/500th of the volume of a 3013 container. Gas compositions were measured periodically overmore » a six year period. The maximum observed gas pressure was 124 kPa. The increase over the initial pressure of 70 kPa was primarily due to generation of nitrogen and carbon dioxide gas. Hydrogen and oxygen were minor components of the headspace gas. At the completion of the study, the internal components of the sealed container showed signs of corrosion.« less

Wigner functions for evanescent waves.

PubMed

Petruccelli, Jonathan C; Tian, Lei; Oh, Se Baek; Barbastathis, George

2012-09-01

We propose phase space distributions, based on an extension of the Wigner distribution function, to describe fields of any state of coherence that contain evanescent components emitted into a half-space. The evanescent components of the field are described in an optical phase space of spatial position and complex-valued angle. Behavior of these distributions upon propagation is also considered, where the rapid decay of the evanescent components is associated with the exponential decay of the associated phase space distributions. To demonstrate the structure and behavior of these distributions, we consider the fields generated from total internal reflection of a Gaussian Schell-model beam at a planar interface.

Clustering and negative feedback by endocytosis in planar cell polarity signaling is modulated by ubiquitinylation of prickle.

PubMed

Cho, Bomsoo; Pierre-Louis, Gandhy; Sagner, Andreas; Eaton, Suzanne; Axelrod, Jeffrey D

2015-05-01

The core components of the planar cell polarity (PCP) signaling system, including both transmembrane and peripheral membrane associated proteins, form asymmetric complexes that bridge apical intercellular junctions. While these can assemble in either orientation, coordinated cell polarization requires the enrichment of complexes of a given orientation at specific junctions. This might occur by both positive and negative feedback between oppositely oriented complexes, and requires the peripheral membrane associated PCP components. However, the molecular mechanisms underlying feedback are not understood. We find that the E3 ubiquitin ligase complex Cullin1(Cul1)/SkpA/Supernumerary limbs(Slimb) regulates the stability of one of the peripheral membrane components, Prickle (Pk). Excess Pk disrupts PCP feedback and prevents asymmetry. We show that Pk participates in negative feedback by mediating internalization of PCP complexes containing the transmembrane components Van Gogh (Vang) and Flamingo (Fmi), and that internalization is activated by oppositely oriented complexes within clusters. Pk also participates in positive feedback through an unknown mechanism promoting clustering. Our results therefore identify a molecular mechanism underlying generation of asymmetry in PCP signaling.

Reductive amination derivatization for the quantification of garlic components by isotope dilution analysis.

PubMed

Lin, Yi-Reng; Huang, Mei-Fang; Wu, You-Ying; Liu, Meng-Chieh; Huang, Jing-Heng; Chen, Ziyu; Shiue, Yow-Ling; Wu, Chia-En; Liang, Shih-Shin

2017-09-01

In this work, we synthesized internal standards for four garlic organosulfur compounds (OSCs) by reductive amination with 13 C, D 2 -formaldehyde, and developed an isotope dilution analysis method to quantitate these organosulfur components in garlic samples. Internal standards were synthesized for internal absolute quantification of S-allylcysteine (SAC), S-allylcysteine sulfoxide (alliin), S-methylcysteine (SMC), and S-ethylcysteine (SEC). We used a multiple reaction monitoring (MRM) to detect 13 C, D 2 -formaldehyde-modified OSCs by ultrahigh-performance liquid phase chromatography coupled with tandem mass spectrometry (UHPLC-MS/MS) and obtained MS spectra showing different ratios of 13 C, D 2 -formaldehyde-modified and H 2 -formaldehyde-modified compounds. The resulting labeled and unlabeled OSCs were exhibited correlation coefficient (R 2 ) ranged from 0.9989 to 0.9994, respectively. The average recoveries for four OSCs at three concentration levels ranged from 89% to 105%. By 13 C, D 2 -formaldehyde and sodium cyanoborohydride, the reductive amination-based method can be utilized to generate novel internal standard for isotope dilution and to extend the quantitative application. Copyright © 2017 Elsevier Ltd. All rights reserved.

Anatomical influences on internally coupled ears in reptiles.

PubMed

Young, Bruce A

2016-10-01

Many reptiles, and other vertebrates, have internally coupled ears in which a patent anatomical connection allows pressure waves generated by the displacement of one tympanic membrane to propagate (internally) through the head and, ultimately, influence the displacement of the contralateral tympanic membrane. The pattern of tympanic displacement caused by this internal coupling can give rise to novel sensory cues. The auditory mechanics of reptiles exhibit more anatomical variation than in any other vertebrate group. This variation includes structural features such as diverticula and septa, as well as coverings of the tympanic membrane. Many of these anatomical features would likely influence the functional significance of the internal coupling between the tympanic membranes. Several of the anatomical components of the reptilian internally coupled ear are under active motor control, suggesting that in some reptiles the auditory system may be more dynamic than previously recognized.

Development of an International Electric Cooperative Initiative on Energy Efficiency

DOE Office of Scientific and Technical Information (OSTI.GOV)

Paul Clark; David South

NRECA conceived of the International Electric Cooperative Initiative on Energy Efficiency (IECIEE) in order to provide an ongoing means of contributing voluntary actions on greenhouse gas emissions mitigation as an integral component of its international programs and projects. This required designing the IECIEE to be integrated directly with the core interests and attributes of participating cooperatives in the U.S. and Latin America, which was the initial focus area selected for the IECIEE. In the case of NRECA International, the core interests related to promoting and strengthening the electric cooperative model, which has proved highly successful in maximizing operational efficiencies inmore » electric power generation, distribution and retailing, as compared to government-owned entities. The approach involved three basic components: (i) establishing the IECIEE mechanism, which involved setting up a functioning organizational vehicle providing for investment, management, and emissions credit accounting; (ii) developing a portfolio of projects in countries where NRECA International could effectively implement the broader mandate of cooperative development as energy efficient suppliers and distributors of electrical energy; and (iii) conducting outreach to obtain the commitment of participants and resources from U.S. and Latin American cooperatives and partnering agencies in the development financing community.« less

Hygroscopic properties of internally mixed particles composed of NaCl and water-soluble organic acids.

PubMed

Ghorai, Suman; Wang, Bingbing; Tivanski, Alexei; Laskin, Alexander

2014-02-18

Atmospheric aging of naturally emitted marine aerosol often leads to formation of internally mixed particles composed of sea salts and water-soluble organic compounds of anthropogenic origin. Mixing of sea salt and organic components has profound effects on the evolving chemical composition and hygroscopic properties of the resulted particles, which are poorly understood. Here, we have studied chemical composition and hygroscopic properties of laboratory generated NaCl particles mixed with malonic acid (MA) and glutaric acid (GA) at different molar ratios using micro-FTIR spectroscopy, atomic force microscopy, and X-ray elemental microanalysis. Hygroscopic properties of internally mixed NaCl and organic acid particles were distinctly different from pure components and varied significantly with the type and amount of organic compound present. Experimental results were in a good agreement with the AIM modeling calculations of gas/liquid/solid partitioning in studied systems. X-ray elemental microanalysis of particles showed that Cl/Na ratio decreased with increasing organic acid component in the particles with MA yielding lower ratios relative to GA. We attribute the depletion of chloride to the formation of sodium malonate and sodium glutarate salts resulted by HCl evaporation from dehydrating particles.

Thermal-hydraulics of internally heated molten salts and application to the Molten Salt Fast Reactor

NASA Astrophysics Data System (ADS)

Fiorina, Carlo; Cammi, Antonio; Luzzi, Lelio; Mikityuk, Konstantin; Ninokata, Hisashi; Ricotti, Marco E.

2014-04-01

The Molten Salt Reactors (MSR) are an innovative kind of nuclear reactors and are presently considered in the framework of the Generation IV International Forum (GIF-IV) for their promising performances in terms of low resource utilization, waste minimization and enhanced safety. A unique feature of MSRs is that molten fluoride salts play the distinctive role of both fuel (heat source) and coolant. The presence of an internal heat generation perturbs the temperature field and consequences are to be expected on the heat transfer characteristics of the molten salts. In this paper, the problem of heat transfer for internally heated fluids in a straight circular channel is first faced on a theoretical ground. The effect of internal heat generation is demonstrated to be described by a corrective factor applied to traditional correlations for the Nusselt number. It is shown that the corrective factor can be fully characterized by making explicit the dependency on Reynolds and Prandtl numbers. On this basis, a preliminary correlation is proposed for the case of molten fluoride salts by interpolating the results provided by an analytic approach previously developed at the Politecnico di Milano. The experimental facility and the related measuring procedure for testing the proposed correlation are then presented. Finally, the developed correlation is used to carry out a parametric investigation on the effect of internal heat generation on the main out-of-core components of the Molten Salt Fast Reactor (MSFR), the reference circulating-fuel MSR design in the GIF-IV. The volumetric power determines higher temperatures at the channel wall, but the effect is significant only in case of large diameters and/or low velocities.

Boiling-Water Reactor internals aging degradation study. Phase 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Luk, K.H.

1993-09-01

This report documents the results of an aging assessment study for boiling water reactor (BWR) internals. Major stressors for BWR internals are related to unsteady hydrodynamic forces generated by the primary coolant flow in the reactor vessel. Welding and cold-working, dissolved oxygen and impurities in the coolant, applied loads and exposures to fast neutron fluxes are other important stressors. Based on results of a component failure information survey, stress corrosion cracking (SCC) and fatigue are identified as the two major aging-related degradation mechanisms for BWR internals. Significant reported failures include SCC in jet-pump holddown beams, in-core neutron flux monitor drymore » tubes and core spray spargers. Fatigue failures were detected in feedwater spargers. The implementation of a plant Hydrogen Water Chemistry (HWC) program is considered as a promising method for controlling SCC problems in BWR. More operating data are needed to evaluate its effectiveness for internal components. Long-term fast neutron irradiation effects and high-cycle fatigue in a corrosive environment are uncertainty factors in the aging assessment process. BWR internals are examined by visual inspections and the method is access limited. The presence of a large water gap and an absence of ex-core neutron flux monitors may handicap the use of advanced inspection methods, such as neutron noise vibration measurements, for BWR.« less

Physicochemical assessment criteria for high-voltage pulse capacitors

NASA Astrophysics Data System (ADS)

Darian, L. A.; Lam, L. Kh.

2016-12-01

In the paper, the applicability of decomposition products of internal insulation of high-voltage pulse capacitors is considered (aging is the reason for decomposition products of internal insulation). Decomposition products of internal insulation of high-voltage pulse capacitors can be used to evaluate their quality when in operation and in service. There have been three generations of markers of aging of insulation as in the case with power transformers. The area of applicability of markers of aging of insulation for power transformers has been studied and the area can be extended to high-voltage pulse capacitors. The research reveals that there is a correlation between the components and quantities of markers of aging of the first generation (gaseous decomposition products of insulation) dissolved in insulating liquid and the remaining life of high-voltage pulse capacitors. The application of markers of aging to evaluate the remaining service life of high-voltage pulse capacitor is a promising direction of research, because the design of high-voltage pulse capacitors keeps stability of markers of aging of insulation in high-voltage pulse capacitors. It is necessary to continue gathering statistical data concerning development of markers of aging of the first generation. One should also carry out research aimed at estimation of the remaining life of capacitors using markers of the second and the third generation.

Episodic and semantic components of autobiographical memories and imagined future events in post-traumatic stress disorder.

PubMed

Brown, Adam D; Addis, Donna Rose; Romano, Tracy A; Marmar, Charles R; Bryant, Richard A; Hirst, William; Schacter, Daniel L

2014-01-01

Individuals with post-traumatic stress disorder (PTSD) tend to retrieve autobiographical memories with less episodic specificity, referred to as overgeneralised autobiographical memory. In line with evidence that autobiographical memory overlaps with one's capacity to imagine the future, recent work has also shown that individuals with PTSD also imagine themselves in the future with less episodic specificity. To date most studies quantify episodic specificity by the presence of a distinct event. However, this method does not distinguish between the numbers of internal (episodic) and external (semantic) details, which can provide additional insights into remembering the past and imagining the future. This study employed the Autobiographical Interview (AI) coding scheme to the autobiographical memory and imagined future event narratives generated by combat veterans with and without PTSD. Responses were coded for the number of internal and external details. Compared to combat veterans without PTSD, those with PTSD generated more external than internal details when recalling past or imagining future events, and fewer internal details were associated with greater symptom severity. The potential mechanisms underlying these bidirectional deficits and clinical implications are discussed.

Thermal reactor for afterburning automotive internal combustion engine exhaust gases

DOE Office of Scientific and Technical Information (OSTI.GOV)

Masaki, K.; Nagaishi, H.

1974-08-08

A thermal reactor for burning unburned components in exhaust gases of an internal combustion engine before emission to the atmosphere is described. An outer casing has an exhaust gas inlet connected to the exhaust ports, and an inner casing divides the reactor into an outer chamber and an inner chamber. The inner casing has an inlet from the outer chamber, an outlet to the atmosphere, and perforations opening to the outer chamber. An oxidation catalyst in the inner chamber promotes oxidation of the unburned components in the exhaust gases to generate oxidation reaction heat. A first secondary air injection nozzlemore » in the inner chamber between the oxidation catalyst and the outlet and a second secondary air injection nozzle in a portion upstream of the oxidation catalyst inject secondary air into oxidation catalyst.« less

Active uptake of sodium in the gills of the hyperregulating shore crab Carcinus maenas

NASA Astrophysics Data System (ADS)

Siebers, D.; Lucu, Č.; Winkler, A.; Dalla Venezia, L.; Wille, H.

1986-03-01

Isolated posterior gills of shore crabs, Carcinus maenas, previously acclimated for at least 1 month to brackish water of 10 ‰ S, were connected with an artificial hemolymph circulation by means of thin polyethylene tubings. Gills were symmetrically perfused and bathed with 50 % sea water. Transepithelial potential differences (PDs) and fluxes of sodium between medium and blood were measured under control conditions and following reductions of PDs by means of 5 mM internal (blood side) ouabain, 0.5 mM internal and external (bathing medium) NaCN or by exhaustion of energy reserves along with a prolonged perfusion period of more than 9 h. In these experiments22Na was used as tracer. Each of the three modes of reducing transepithelial potential differences resulted in a decrease in sodium influxes from 500 1000 µmoles g-1 h-1 to 250 400 µmoles g-1 h-1. The findings suggest that sodium influx, which normally greatly exceeds efflux, was diminished by its active component. The remaining non-inhibitable influx equals efflux values. Our findings thus indicate that efflux is completely passive, while influx has — beside a passive component of efflux magnitudes — an additional active portion which is much larger than the passive component. Since ouabain is a specific inhibitor of the Na-K-ATPase, our results confirm previous findings (Siebers et al., 1985) that the basolaterally located Na-K-ATPase generates the transepithelial potential difference in the gills, which is inside negative by about 6 12 mV. Inhibition of the active portion of sodium influx by internal ouabain along with reduced PDs suggests that transepithelial PDs generated by the branchial sodium pump are the driving force for active sodium uptake in hyperregulating brackish water crabs.

Aging management program of the reactor building concrete at Point Lepreau Generating Station

NASA Astrophysics Data System (ADS)

Aldea, C.-M.; Shenton, B.; Demerchant, M. M.; Gendron, T.

2011-04-01

In order for New Brunswick Power Nuclear (NBPN) to control the risks of degradation of the concrete reactor building at the Point Lepreau Generating Station (PLGS) the development of an aging management plan (AMP) was initiated. The intention of this plan was to determine the requirements for specific structural components of concrete of the reactor building that require regular inspection and maintenance to ensure the safe and reliable operation of the plant. The document is currently in draft form and presents an integrated methodology for the application of an AMP for the concrete of the reactor building. The current AMP addresses the reactor building structure and various components, such as joint sealant and liners that are integral to the structure. It does not include internal components housed within the structure. This paper provides background information regarding the document developed and the strategy developed to manage potential degradation of the concrete of the reactor building, as well as specific programs and preventive and corrective maintenance activities initiated.

Development of the Second Generation International Space Station (ISS) Total Organic Carbon Analyzer (TOCA)

NASA Technical Reports Server (NTRS)

Clements, Anna L.; Stinson, Richard G.; VanWie, Michael; Warren, Eric

2009-01-01

The second generation International Space Station (ISS) Total Organic Carbon Analyzer s (TOCA) function is to monitor concentrations of Total Organic Carbon (TOC) in ISS water samples. TOC is one measurement that provides a general indication of overall water quality by indicating the potential presence of hazardous chemicals. The data generated from the TOCA is used as a hazard control to assess the quality of the reclaimed and stored water supplies on-orbit and their suitability for crew consumption. This paper details the unique ISS Program requirements, the design of the ISS TOCA, and a brief description of the on-orbit concept-of-operations. The TOCA schematic will be discussed in detail along with specific information regarding key components. The ISS TOCA was designed as a non-toxic TOC analyzer that could be deployed in a flight ready package. This basic concept was developed through laboratory component level testing, two moderate fidelity integrated system breadboard prototypes, a flight-like full scale prototype, as well as lessons learned from the inadequacies of the first unit. The result: a new TOCA unit that is robust in design and includes special considerations to microgravity and the on-orbit ISS environment. TOCA meets the accuracy needs of the ISS Program with a 1,000 to 25,000 g/L range, accurate to within +/-25%.

MIS High-Purity Plutonium Oxide Metal Oxidation Product TS707001 (SSR123): Final Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Veirs, Douglas Kirk; Stroud, Mary Ann; Berg, John M.

A high-purity plutonium dioxide material from the Material Identification and Surveillance (MIS) Program inventory has been studied with regard to gas generation and corrosion in a storage environment. Sample TS707001 represents process plutonium oxides from several metal oxidation operations as well as impure and scrap plutonium from Hanford that are currently stored in 3013 containers. After calcination to 950°C, the material contained 86.98% plutonium with no major impurities. This study followed over time, the gas pressure of a sample with nominally 0.5 wt% water in a sealed container with an internal volume scaled to 1/500th of the volume of amore » 3013 container. Gas compositions were measured periodically over a six year period. The maximum observed gas pressure was 138 kPa. The increase over the initial pressure of 80 kPa was primarily due to generation of nitrogen and carbon dioxide gas in the first six months. Hydrogen and oxygen were minor components of the headspace gas. At the completion of the study, the internal components of the sealed container showed signs of corrosion, including pitting.« less

Synchronized voltage contrast display analysis system

NASA Technical Reports Server (NTRS)

Johnston, M. F.; Shumka, A.; Miller, E.; Evans, K. C. (Inventor)

1982-01-01

An apparatus and method for comparing internal voltage potentials of first and second operating electronic components such as large scale integrated circuits (LSI's) in which voltage differentials are visually identified via an appropriate display means are described. More particularly, in a first embodiment of the invention a first and second scanning electron microscope (SEM) are configured to scan a first and second operating electronic component respectively. The scan pattern of the second SEM is synchronized to that of the first SEM so that both simultaneously scan corresponding portions of the two operating electronic components. Video signals from each SEM corresponding to secondary electron signals generated as a result of a primary electron beam intersecting each operating electronic component in accordance with a predetermined scan pattern are provided to a video mixer and color encoder.

SMART Structures User's Guide - Version 3.0

NASA Technical Reports Server (NTRS)

Spangler, Jan L.

1996-01-01

Version 3.0 of the Solid Modeling Aerospace Research Tool (SMART Structures) is used to generate structural models for conceptual and preliminary-level aerospace designs. Features include the generation of structural elements for wings and fuselages, the integration of wing and fuselage structural assemblies, and the integration of fuselage and tail structural assemblies. The highly interactive nature of this software allows the structural engineer to move quickly from a geometry that defines a vehicle's external shape to one that has both external components and internal components which may include ribs, spars, longerons, variable depth ringframes, a floor, a keel, and fuel tanks. The geometry that is output is consistent with FEA requirements and includes integrated wing and empennage carry-through and frame attachments. This report provides a comprehensive description of SMART Structures and how to use it.

Computed tomography (CT) as a nondestructive test method used for composite helicopter components

NASA Astrophysics Data System (ADS)

Oster, Reinhold

1991-09-01

The first components of primary helicopter structures to be made of glass fiber reinforced plastics were the main and tail rotor blades of the Bo105 and BK 117 helicopters. These blades are now successfully produced in series. New developments in rotor components, e.g., the rotor blade technology of the Bo108 and PAH2 programs, make use of very complex fiber reinforced structures to achieve simplicity and strength. Computer tomography was found to be an outstanding nondestructive test method for examining the internal structure of components. A CT scanner generates x-ray attenuation measurements which are used to produce computer reconstructed images of any desired part of an object. The system images a range of flaws in composites in a number of views and planes. Several CT investigations and their results are reported taking composite helicopter components as an example.

Computed Tomography (CT) as a nondestructive test method used for composite helicopter components

NASA Astrophysics Data System (ADS)

Oster, Reinhold

The first components of primary helicopter structures to be made of glass fiber reinforced plastics were the main and tail rotor blades of the Bo105 and BK117 helicopters. These blades are now successfully produced in series. New developments in rotor components, e.g. the rotor blade technology of the Bo108 and PAH2 programs, make use of very complex fiber reinforced structures to achieve simplicity and strength. Computer tomography was found to be an outstanding nondestructive test method for examining the internal structure of components. A CT scanner generates x-ray attenuation measurements which are used to produce computer reconstructed images of any desired part of an object. The system images a range of flaws in composites in a number of views and planes. Several CT investigations and their results are reported taking composite helicopter components as an example.

Automated extraction of knowledge for model-based diagnostics

NASA Technical Reports Server (NTRS)

Gonzalez, Avelino J.; Myler, Harley R.; Towhidnejad, Massood; Mckenzie, Frederic D.; Kladke, Robin R.

1990-01-01

The concept of accessing computer aided design (CAD) design databases and extracting a process model automatically is investigated as a possible source for the generation of knowledge bases for model-based reasoning systems. The resulting system, referred to as automated knowledge generation (AKG), uses an object-oriented programming structure and constraint techniques as well as internal database of component descriptions to generate a frame-based structure that describes the model. The procedure has been designed to be general enough to be easily coupled to CAD systems that feature a database capable of providing label and connectivity data from the drawn system. The AKG system is capable of defining knowledge bases in formats required by various model-based reasoning tools.

The rise and fall of the Pacific Northwest log export market.

Treesearch

Jean M. Daniels

2005-01-01

For decades, softwood log exports were an important component of international wood products trade from the Pacific Northwest (PNW) region of the United States. Log exports to the Pacific Rim began in earnest after the Columbus Day Storm of 1962 generated billions of board feet of salvaged timber. This market was maintained and expanded owing to Japan’s demand for high...

Physicochemical assessment criteria for high-voltage pulse capacitors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Darian, L. A., E-mail: LDarian@rambler.ru; Lam, L. Kh.

In the paper, the applicability of decomposition products of internal insulation of high-voltage pulse capacitors is considered (aging is the reason for decomposition products of internal insulation). Decomposition products of internal insulation of high-voltage pulse capacitors can be used to evaluate their quality when in operation and in service. There have been three generations of markers of aging of insulation as in the case with power transformers. The area of applicability of markers of aging of insulation for power transformers has been studied and the area can be extended to high-voltage pulse capacitors. The research reveals that there is amore » correlation between the components and quantities of markers of aging of the first generation (gaseous decomposition products of insulation) dissolved in insulating liquid and the remaining life of high-voltage pulse capacitors. The application of markers of aging to evaluate the remaining service life of high-voltage pulse capacitor is a promising direction of research, because the design of high-voltage pulse capacitors keeps stability of markers of aging of insulation in high-voltage pulse capacitors. It is necessary to continue gathering statistical data concerning development of markers of aging of the first generation. One should also carry out research aimed at estimation of the remaining life of capacitors using markers of the second and the third generation.« less

Development of performance criteria for advanced Viking seismic experiments

NASA Technical Reports Server (NTRS)

1972-01-01

The characteristics and requirements of the seismic instrument for mapping the internal structure of the planet Mars are briefly described. The types of signals expected to exist are microseismic background generated by wind and pressure variations and thermal effects, disturbances of or in the landed vehicle, signals caused by faulting and volcanic activity, and signals due to meteoritic impacts. The advanced instrument package should include a short-period vertical component system, a long-period or wide-band 3-component system, a high frequency vertical component system, and a system for detection and rejection of lander noises. The Viking '75, Surveyor, and Apollo systems are briefly described as potential instruments to be considered for modification. Data processing and control systems are also summarized.

Systems and methods for imaging using radiation from laser produced plasmas

DOEpatents

Renard-Le Galloudec, Nathalie; Cowan, Thomas E.; Sentoku, Yasuhiko; Rassuchine, Jennifer

2009-06-30

In particular embodiments, the present disclosure provides systems and methods for imaging a subject using radiation emitted from a laser produced plasma generating by irradiating a target with a laser. In particular examples, the target includes at least one radiation enhancing component, such as a fluor, cap, or wire. In further examples, the target has a metal layer and an internal surface defining an internal apex, the internal apex of less than about 15 .mu.m, such as less than about 1 .mu.m. The targets may take a variety of shapes, including cones, pyramids, and hemispheres. Certain aspects of the present disclosure provide improved imaging of a subject, such as improved medical images of a radiation dose than typical conventional methods and systems.

International Test Program for Synergistic Atomic Oxygen and Vacuum Ultraviolet Radiation Exposure of Spacecraft Materials

NASA Technical Reports Server (NTRS)

Miller, Sharon K.

2001-01-01

The components and materials of spacecraft in low Earth orbit can degrade in thermal and optical performance through interaction with atomic oxygen and vacuum ultraviolet (VUV) radiation, which are predominant in low Earth orbit. Because of the importance of low Earth orbit durability and performance to manufacturers and users, an international test program for assessing the durability of spacecraft materials and components was initiated. Initial tests at the NASA Glenn Research Center consisted of exposure of samples representing a variety of thermal control paints, multilayer insulation materials, and Sun sensors that have been used in space. Materials donated from various international sources were tested alongside materials whose performance is well known, such as Teflon FEP, Kapton H, or Z-93-P white paint. The optical, thermal, or mass loss data generated during the tests were then provided to the participating material suppliers. Data were not published unless the participant donating the material consented to publication. The test program is intended to give spacecraft builders and users a better understanding of degradation processes and effects so that they can improve their predictions of spacecraft performance.

Polarization-resolved second-harmonic generation microscopy as a method to visualize protein-crystal domains

PubMed Central

DeWalt, Emma L.; Begue, Victoria J.; Ronau, Judith A.; Sullivan, Shane Z.; Das, Chittaranjan; Simpson, Garth J.

2013-01-01

Polarization-resolved second-harmonic generation (PR-SHG) microscopy is described and applied to identify the presence of multiple crystallographic domains within protein-crystal conglomerates, which was confirmed by synchrotron X-ray diffraction. Principal component analysis (PCA) of PR-SHG images resulted in principal component 2 (PC2) images with areas of contrasting negative and positive values for conglomerated crystals and PC2 images exhibiting uniformly positive or uniformly negative values for single crystals. Qualitative assessment of PC2 images allowed the identification of domains of different internal ordering within protein-crystal samples as well as differentiation between multi-domain conglomerated crystals and single crystals. PR-SHG assessments of crystalline domains were in good agreement with spatially resolved synchrotron X-ray diffraction measurements. These results have implications for improving the productive throughput of protein structure determination through early identification of multi-domain crystals. PMID:23275165

An overview of ALARA considerations during Yankee Atomic`s Component Removal Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Granados, B.; Babineau, G.; Colby, B.

1995-03-01

In Februrary 1992, Yankee Atomic Electric Company (YAEC) permanently shutdown Yankee Nuclear Power Station in Rowe, Massachusetts, after thirty-two years of efficient operation. Yankee`s plan decommissioning is to defer dismantlement until a low level radioactive waste (LLRW) disposal facility is available. The plant will be maintained in a safe storage condition until a firm contract for the disposal of LLRW generated during decommissioning can be secured. Limited access to a LLRW disposal facility may occur during the safe storage period. Yankee intends to use these opportunities to remove components and structures. A Component Removal Project (CRP) was initiated in 1993more » to take advantage of one of these opportunities. A Componenet Removal Project (CRP) was initiated in 1993 to take advantage of one of these opportunities. The CRP includes removal of four steam generators, the pressurizer, and segmentation of reactor vessel internals and preparation of LLRW for shipment and disposal at Chem-Nuclear`s Barnwell, South Carolina facility. The CRP is projected to be completed by June 1994 at an estimated total worker exposure of less than 160 person-rem.« less

A summary of sodium-cooled fast reactor development

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aoto, Kazumi; Dufour, Philippe; Hongyi, Yang

Much of the basic technology for the Sodium-cooled fast Reactor (SFR) has been established through long term development experience with former fast reactor programs, and is being confirmed by the Phénix end-of-life tests in France, the restart of Monju in Japan, the lifetime extension of BN-600 in Russia, and the startup of the China Experimental Fast Reactor in China. Planned startup in 2014 for new SFRs: BN-800 in Russia and PFBR in India, will further enhance the confirmation of the SFR basic technology. Nowadays, the SFR development has advanced to aiming at establishment of the Generation-IV system which is dedicatedmore » to sustainable energy generation and actinide management, and several advanced SFR concepts are under development such as PRISM, JSFR, ASTRID, PGSFR, BN-1200, and CFR-600. Generation-IV International Forum is an international collaboration framework where various R&D activities are progressing on design of system and component, safety and operation, advanced fuel, and actinide cycle for the Generation-IV SFR development, and will play a beneficial role of promoting them thorough providing an opportunity to share the past experience and the latest data of design and R&D among countries developing SFR.« less

Gyrofluid Simulations of Intrinsic Rotation Generation in Reversed Shear Plasmas with Internal Transport Barriers

NASA Astrophysics Data System (ADS)

Jhang, Hogun; Kim, S. S.; Kwon, J. M.; Terzolo, L.; Kim, J. Y.; Diamond, P. H.

2010-11-01

It is accepted that the intrinsic rotation is generated via the residual stress, which is non-diffusive components of the turbulent Reynolds stress, without external momentum input. The physics leading to the onset of intrinsic rotation in L- and H- mode plasmas have been elucidated elsewhere. However, the physics responsible for the generation and transport of the intrinsic rotation and its relationship to the formation of internal transport barriers (ITBs) in reversed shear (RS) plasmas have not been explored in detail, which is the main subject in the present work. The revised version of the global gyrofluid code TRB is used for this study. It is found that the large intrinsic rotation (˜10-30% of the ion sound speed depending on ITB characteristics) is generated near the ITB region and propagates into the core. The intrinsic rotation increases linearly as the temperature gradient at ITB position increases, albeit not indefinitely. Key parameters related to the symmetry breaking, such as turbulent intensity and its gradient, the flux surface averaged parallel wavenumber are evaluated dynamically during the ITB formation. In particular, the role of reversed shear and the q-profile curvature is presented in relation to the symmetry breaking in RS plasmas.

DOE Office of Scientific and Technical Information (OSTI.GOV)

R.A. Wigeland

Abstract: The proposed Global Nuclear Energy Partnership (GNEP) Program, which is part of the President’s Advanced Energy Initiative, is intended to support a safe, secure, and sustainable expansion of nuclear energy, both domestically and internationally. Domestically, the GNEP Program would promote technologies that support economic, sustained production of nuclear-generated electricity, while reducing the impacts associated with spent nuclear fuel disposal and reducing proliferation risks. The Department of Energy (DOE) proposed action envisions changing the United States nuclear energy fuel cycle from an open (or once-through) fuel cycle—in which nuclear fuel is used in a power plant one time and themore » resulting spent nuclear fuel is stored for eventual disposal in a geologic repository—to a closed fuel cycle in which spent nuclear fuel would be recycled to recover energy-bearing components for use in new nuclear fuel. At this time, DOE has no specific proposed actions for the international component of the GNEP Program. Rather, the United States, through the GNEP Program, is considering various initiatives to work cooperatively with other nations. Such initiatives include the development of grid-appropriate reactors and the development of reliable fuel services (to provide an assured supply of fresh nuclear fuel and assist with the management of the used fuel) for nations who agree to employ nuclear energy only for peaceful purposes, such as electricity generation.« less

Concept of Draft International Standard for a Unified Approach to Space Program Quality Assurance

NASA Astrophysics Data System (ADS)

Stryzhak, Y.; Vasilina, V.; Kurbatov, V.

2002-01-01

For want of the unified approach to guaranteed space project and product quality assurance, implementation of many international space programs has become a challenge. Globalization of aerospace industry and participation of various international ventures with diverse quality assurance requirements in big international space programs requires for urgent generation of unified international standards related to this field. To ensure successful fulfillment of space missions, aerospace companies should design and process reliable and safe products with properties complying or bettering User's (or Customer's) requirements. Quality of the products designed or processed by subcontractors (or other suppliers) should also be in compliance with the main user (customer)'s requirements. Implementation of this involved set of unified requirements will be made possible by creating and approving a system (series) of international standards under a generic title Space Product Quality Assurance based on a system consensus principle. Conceptual features of the baseline standard in this system (series) should comprise: - Procedures for ISO 9000, CEN and ECSS requirements adaptation and introduction into space product creation, design, manufacture, testing and operation; - Procedures for quality assurance at initial (design) phases of space programs, with a decision on the end product made based on the principle of independence; - Procedures to arrange incoming inspection of products delivered by subcontractors (including testing, audit of supplier's procedures, review of supplier's documentation), and space product certification; - Procedures to identify materials and primary products applied; - Procedures for quality system audit at the component part, primary product and materials supplier facilities; - Unified procedures to form a list of basic performances to be under configuration management; - Unified procedures to form a list of critical space product components, and unified procedures to define risks related to the specific component application and evaluate safety for the entire program implementation. In the eyes of the authors, those features together with a number of other conceptual proposals should constitute a unified standard-technical basis for implementing international space programs.

Axial-Stereo 3-D Optical Metrology for Inner Profile of Pipes Using a Scanning Laser Endoscope

NASA Astrophysics Data System (ADS)

Gong, Yuanzheng; Johnston, Richard S.; Melville, C. David; Seibel, Eric J.

2015-07-01

As the rapid progress in the development of optoelectronic components and computational power, 3-D optical metrology becomes more and more popular in manufacturing and quality control due to its flexibility and high speed. However, most of the optical metrology methods are limited to external surfaces. This article proposed a new approach to measure tiny internal 3-D surfaces with a scanning fiber endoscope and axial-stereo vision algorithm. A dense, accurate point cloud of internally machined threads was generated to compare with its corresponding X-ray 3-D data as ground truth, and the quantification was analyzed by Iterative Closest Points algorithm.

Utilization of Additive Manufacturing in Evaluating the Performance of Internally Defected Materials

NASA Astrophysics Data System (ADS)

Mourad, A.-H. I.; Ghazal, A. M.; Syam, M. M.; Qadi, O. D. Al; Jassmi, H. Al

2018-05-01

The elimination of internal defects in a material present in the raw material or generated during the manufacturing or service is difficult. The inclusions of the defects have an adverse effect on the load bearing capacity. The presence of the cracks subjected to a specific orientation in materials or machinery can cause devastating unexpected failure during operation. Analysis of the failure in the components with cracks is more confined to analytical and numerical evaluation. The experimental evaluation has been tedious due to the complexity of replicating the actual defected component. The potential of additive manufacturing in developing user-defined components with cracks for the experimental evaluation is explored in this research. The present research investigated the effect of the internal elliptical cracks aligned at different orientations on the mechanical performance of polylactic acid (Green filament). The Fusion Deposition Method was utilized for the development of the standard tensile specimens with internal elliptical crack oriented at 0°, 45° and 90° using UltiMaker 2. The results proved that there is a considerable reduction in the load bearing capacity due to the presence of the cracks. The maximum load bearing capacity decreased by 15.01% for the specimen with crack inclined at 0° to the lateral axis compared to crack- free specimen. The nature of the fracture and the stress-strain graph evidently showcase the brittle nature of the material. The SEM image of the fractured region proved the phenomenal characteristics such as strong adhesion between the layers and the proper material flow. In the light of the results of this work, it can be concluded that the 3-D printing methodology is effective for evaluating the mechanical performance of the internally defected material.

Health literacy and disability: differences between generations of Canadian immigrants.

PubMed

Omariba, D Walter Rasugu; Ng, Edward

2015-03-01

To determine whether there are differences in disability by immigrant generation and region of origin and recency of arrival in Canada, and the role of health literacy in this relationship. A secondary analysis of the Canadian component of the 2003 International Adult Literacy and Skills Survey (IALSS) was undertaken. Compared to the third-plus generation, first-generation immigrants were less likely to report disability; these differences remained even after adjustment for sociodemographic and socioeconomic factors. No differences in disability were observed between the second- and third-plus generations. Among first-generation immigrants, those not from Europe or USA were less likely to report disability regardless of their duration in Canada. Health literacy was negatively associated with disability only in the analysis comparing generations of Canadians. However, its effect was largely accounted for by education, employment status and income. First-generation immigrants were less likely to be disabled than the other generations. Education, employment and income provide important avenues through which individuals develop health literacy. Health literacy was not associated with disability among first-generation immigrants perhaps because health literacy is low in this group.

Bistable (latching) solenoid actuated propellant isolation valve

NASA Technical Reports Server (NTRS)

Wichmann, H.; Deboi, H. H.

1979-01-01

The design, fabrication, assembly and test of a development configuration bistable (latching) solenoid actuated propellant isolation valve suitable for the control hydrazine and liquid fluorine to an 800 pound thrust rocket engine is described. The valve features a balanced poppet, utilizing metal bellows, a hard poppet/seat interface and a flexure support system for the internal moving components. This support system eliminates sliding surfaces, thereby rendering the valve free of self generated particles.

Heat exchange equipment and valve design and operability improvement. NE-Volume 14

DOE Office of Scientific and Technical Information (OSTI.GOV)

Singh, K.P; Niyogi, K.K.

1994-12-31

The papers contained in this volume were presented at the Maurice Holtz Memorial Sessions on Heat Exchanger Equipment and Valve Design and Operability Improvement, as part of the 1994 International Joint Power Generation Conference and Exhibition, October 2--6, in Phoenix, Arizona. These eight papers deal with two types of components--heat exchangers and valves, both of which are used in practically all sensors of the nuclear industry.

Downhole Data Transmission System

DOEpatents

Hall, David R.; Hall, Jr., H. Tracy; Pixton, David; Dahlgren, Scott; Fox, Joe

2004-04-06

A system for transmitting data through a string of down-hole components. In accordance with one aspect, the system includes a plurality of downhole components, such as sections of pipe in a drill string. Each downhole component includes a pin end and a box end, with the pin end of one downhole component being adapted to be connected to the box end of another. Each pin end includes external threads and an internal pin face distal to the external threads. Each box end includes an internal shoulder face with internal threads distal to the internal shoulder face. The internal pin face and the internal shoulder face are aligned with and proximate each other when the pin end of the one component is threaded into a box end of the other component.

The Association of Polar Early Career Scientists (APECS): A Model for the Professional Development of Scientists (Invited)

NASA Astrophysics Data System (ADS)

Baeseman, J. L.; Apecs Leadership Team

2010-12-01

Efforts like the International Polar Year 2007-2008 (IPY) have helped to increase research efforts as well as enhancing the integration of education and outreach into research projects and developing the next generation of researchers. One of the major legacies of the IPY was the creation of the Association of Polar Early Career Scientists (APECS), which was developed in 2006 by young researchers and focuses on helping each other develop the skills needed for successful careers in research by working with senior mentors. APECS is an international and interdisciplinary organization of over 2000 early career researchers and educators with interests in the Polar Regions and the wider cryosphere from 45 countries. APECS aims to stimulate interdisciplinary and international research collaborations, and develop effective future leaders in polar research, education and outreach. This is achieved by - Facilitating international and interdisciplinary networking opportunities to share ideas and experiences and to develop new research directions and collaborations, - Providing opportunities for professional career development for both academic and alternative research professions, and - Promoting education and outreach as an integral component of polar research and to stimulate future generations of polar researchers. Since its inception, APECS has strived to develop a strong network of partnerships with senior international organizations and scientific bodies to provide career development opportunities for young researchers. These partnerships have led to early-career representation on science planning bodies at an international level, the mandate of early career researchers serving as co-chairs at science conferences, the development of a mentorship program, field schools and techniques workshops, mentor panel discussions at conferences and increased funding for young researchers to attend conferences. APECS has also worked with an international teachers network to develop “Polar Science and Global Climate: An International Resource Guide for Teachers and Researchers” which includes tips and tricks for scientists in communicating their research effectively. Because of its international membership, APECS used the internet as an effective tool to develop skills through a career development webinar series, literature discussion forum, and a virtual poster session where researchers can continue to present their research long after a conference poster session ends. These programs not only serve as ways for young researchers to develop their research, they also serve to provide leadership training to the many individuals who plan these activities and creates a strong sense of community across disciplinary and national boarders. The tools APECS has developed can be used to train the next generation of researchers in any field. But perhaps what is more important are the lessons learned from nurturing the organization to create a strong community of early career and senior researchers helping and motivating each other to improve and stay connected to research careers. This presentation will demonstrate how a young researcher driven effort can become an important and crucial component of any field of research on both the national and international level.

Internal reforming of methane in solid oxide fuel cell systems

NASA Astrophysics Data System (ADS)

Peters, R.; Dahl, R.; Klüttgen, U.; Palm, C.; Stolten, D.

Internal reforming is an attractive option offering a significant cost reduction, higher efficiencies and faster load response of a solid oxide fuel cell (SOFC) power plant. However, complete internal reforming may lead to several problems which can be avoided with partial pre-reforming of natural gas. In order to achieve high total plant efficiency associated with low energy consumption and low investment costs, a process concept has been developed based on all the components of the SOFC system. In the case of anode gas recycling an internal steam circuit exists. This has the advantage that there is no need for an external steam generator and the steam concentration in the anode gas is reduced. However, anode gas recycling has to be proven by experiments in a pre-reformer and for internal reforming. The addition of carbon dioxide clearly shows a decrease in catalyst activity, while for temperatures higher than 1000 K hydrogen leads to an increase of the measured methane conversion rates.

Does Humeral Component Lateralization in Reverse Shoulder Arthroplasty Affect Rotator Cuff Torque? Evaluation in a Cadaver Model.

PubMed

Chan, Kevin; Langohr, G Daniel G; Mahaffy, Matthew; Johnson, James A; Athwal, George S

2017-10-01

Humeral component lateralization in reverse total shoulder arthroplasty (RTSA) may improve the biomechanical advantage of the rotator cuff, which could improve the torque generated by the rotator cuff and increase internal and external rotation of the shoulder. The purpose of this in vitro biomechanical study was to evaluate the effect of humeral component lateralization (or lateral offset) on the torque of the anterior and posterior rotator cuff. Eight fresh-frozen cadaveric shoulders from eight separate donors (74 ± 8 years; six males, two females) were tested using an in vitro simulator. All shoulders were prescreened for soft tissue deficit and/or deformity before testing. A custom RTSA prosthesis was implanted that allowed five levels of humeral component lateralization (15, 20, 25, 30, 35 mm), which avoided restrictions imposed by commercially available designs. The torques exerted by the anterior and posterior rotator cuff were measured three times and then averaged for varying humeral lateralization, abduction angle (0°, 45°, 90°), and internal and external rotation (-60°, -30°, 0°, 30°, 60°). A three-way repeated measures ANOVA (abduction angle, humeral lateralization, internal rotation and external rotation angles) with a significance level of α = 0.05 was used for statistical analysis. Humeral lateralization only affected posterior rotator cuff torque at 0° abduction, where increasing humeral lateralization from 15 to 35 mm at 60° internal rotation decreased external rotation torque by 1.6 ± 0.4 Nm (95% CI, -0.07 -1.56 Nm; p = 0.06) from 4.0 ± 0.3 Nm to 2.4 ± 0.6 Nm, respectively, but at 60° external rotation increased external rotation torque by 2.2 ± 0.5 Nm (95% CI, -4.2 to -0.2 Nm; p = 0.029) from 6.2 ± 0.5 Nm to 8.3 ± 0.5 Nm, respectively. Anterior cuff torque was affected by humeral lateralization in more arm positions than the posterior cuff, where increasing humeral lateralization from 15 to 35 mm when at 60° internal rotation increased internal rotation torque at 0°, 45°, and 90° abduction by 3.2 ± 0.5 Nm (95% CI, 1.1-5.2 Nm; p = 0.004) from 6.6 ± 0.6 Nm to 9.7 ± 0.6 Nm, 4.0 ± 0.3 Nm (95% CI, 2.8-5.0 Nm; p < 0.001) from 1.7 ± 1.0 Nm to 5.6 ± 0.9 Nm, and 2.2 ± 0.2 Nm (95% CI, 1.4-2.9 Nm; p < 0.001) from 0.6 ± 0.6 Nm to 2.8 ± 0.6 Nm, respectively. In neutral internal and external rotation, increasing humeral lateral offset from 15 to 35 mm increased the internal rotation torque at 45˚ and 90˚ abduction by 1.5 ± 0.3 Nm (95% CI, 0.2-2.7 Nm; p = 0.02) and 1.3 ± 0.2 Nm (95% CI, 0.4-2.3 Nm; p < 0.001), respectively. Humeral component lateralization improves rotator cuff torque. The results of this preliminary in vitro cadaveric study suggest that the lateral offset of the RTSA humeral component plays an important role in the torque generated by the anterior and posterior rotator cuff. However, further studies are needed before clinical application of these results. Increasing humeral offset may have adverse effects, such as the increased risk of implant modularity, increasing tension of the cuff and soft tissues, increased costs often associated with design modifications, and other possible as yet unforeseen negative consequences.

Hygroscopic Properties of Internally Mixed Particles Composed of NaCl and Water-Soluble Organic Acids

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ghorai, Suman; Wang, Bingbing; Tivanski, Alexei V.

Atmospheric aging of naturally emitted marine aerosol often leads to formation of internally mixed particles composed of sea salts and water soluble organic compounds of anthropogenic origin. Mixing of sea salt and organic components has profound effects on the evolving chemical composition and hygroscopic properties of the resulted particles, which are poorly understood. Here, we have studied chemical composition and hygroscopic properties of laboratory generated NaCl particles mixed with malonic acid (MA) and glutaric acid (GA) at different molar ratios using micro-FTIR spectroscopy and X-ray elemental microanalysis.Hygroscopic properties of inte rnally mixed NaCl and organic acid particles were distinctly differentmore » from pure components and varied significantly with the type and amount of organic compound present. Experimental results were in a good agreement with the AIM modeling calculations of gas/liquid/solid partitioning in studied systems. X-ray elemental microanalysis of particles showed that Cl/Na ratio decreased with increasing organic acid component in the particles with MA yielding lower ratios relative to GA. We attribute the depletion of chloride to the formation of Na-malonate and Na-glutarate salts resulted by HCl evaporation from dehydrating particles.« less

Supersonic gas-liquid cleaning system

NASA Technical Reports Server (NTRS)

Caimi, Raoul E. B.; Thaxton, Eric A.

1994-01-01

A system to perform cleaning and cleanliness verification is being developed to replace solvent flush methods using CFC 113 for fluid system components. The system is designed for two purposes: internal and external cleaning and verification. External cleaning is performed with the nozzle mounted at the end of a wand similar to a conventional pressure washer. Internal cleaning is performed with a variety of fixtures designed for specific applications. Internal cleaning includes tubes, pipes, flex hoses, and active fluid components such as valves and regulators. The system uses gas-liquid supersonic nozzles to generate high impingement velocities at the surface of the object to be cleaned. Compressed air or any inert gas may be used to provide the conveying medium for the liquid. The converging-diverging nozzles accelerate the gas-liquid mixture to supersonic velocities. The liquid being accelerated may be any solvent including water. This system may be used commercially to replace CFC and other solvent cleaning methods widely used to remove dust, dirt, flux, and lubricants. In addition, cleanliness verification can be performed without the solvents which are typically involved. This paper will present the technical details of the system, the results achieved during testing at KSC, and future applications for this system.

Supersonic gas-liquid cleaning system

NASA Astrophysics Data System (ADS)

Caimi, Raoul E. B.; Thaxton, Eric A.

1994-02-01

A system to perform cleaning and cleanliness verification is being developed to replace solvent flush methods using CFC 113 for fluid system components. The system is designed for two purposes: internal and external cleaning and verification. External cleaning is performed with the nozzle mounted at the end of a wand similar to a conventional pressure washer. Internal cleaning is performed with a variety of fixtures designed for specific applications. Internal cleaning includes tubes, pipes, flex hoses, and active fluid components such as valves and regulators. The system uses gas-liquid supersonic nozzles to generate high impingement velocities at the surface of the object to be cleaned. Compressed air or any inert gas may be used to provide the conveying medium for the liquid. The converging-diverging nozzles accelerate the gas-liquid mixture to supersonic velocities. The liquid being accelerated may be any solvent including water. This system may be used commercially to replace CFC and other solvent cleaning methods widely used to remove dust, dirt, flux, and lubricants. In addition, cleanliness verification can be performed without the solvents which are typically involved. This paper will present the technical details of the system, the results achieved during testing at KSC, and future applications for this system.

Study of internal gravity waves in the meteor zone

NASA Technical Reports Server (NTRS)

Gavrilov, N. M.

1987-01-01

An important component of the dynamical regime of the atmosphere at heights near 100 km are internal gravity waves (IGW) with periods from about 5 min to about 17.5 hrs which propagate from the lower atmospheric layers and are generated in the uppermost region of the atmosphere. As IGW propagate upwards, their amplitudes increase and they have a considerable effect on upper atmospheric processes: (1) they provide heat flux divergences comparable with solar heating; (2) they influence the gaseous composition and produce wave variations of the concentrations of gaseous components and emissions of the upper atmosphere; and (3) they cause considerable acceleration of the mean stream. It was concluded that the periods, wavelengths, amplitudes and velocities of IGW propagation in the meteor zone are now measured quite reliably. However, for estimating the influence of IGW on the thermal regime and the circulation of the upper atmosphere these parameters are not as important as the values of wave fluxes of energy, heat, moment and mass.

Generating grids directly on CAD database surfaces using a parametric evaluator approach

NASA Technical Reports Server (NTRS)

Gatzhe, Timothy D.; Melson, Thomas G.

1995-01-01

A very important, but often overlooked step in grid generation is acquiring a suitable geometry definition of the vehicle to be analyzed. In the past, geometry was usually obtained by generating a number of cross-sections of each component. A number of recent efforts have focussed on non-uniform rational B-spline surfaces (NURBS) to provide as single type of analytic surface to deal with inside the grid generator. This approach has required the development of tools to read other types of surfaces and convert them, either exactly or by approximation, into a NURBS surface. This paper describes a more generic parametric evaluator approach, which does not rely on a particular surface type internal to the grid generation system and is less restrictive in the number of surface types that can be represented exactly. This approach has been implemented in the McDonnell Douglas grid generation system, MACGS, and offers direct access to all types of surfaces from a Unigraphics part file.

A Simulink Library of cryogenic components to automatically generate control schemes for large Cryorefrigerators

NASA Astrophysics Data System (ADS)

Bonne, François; Alamir, Mazen; Hoa, Christine; Bonnay, Patrick; Bon-Mardion, Michel; Monteiro, Lionel

2015-12-01

In this article, we present a new Simulink library of cryogenics components (such as valve, phase separator, mixer, heat exchanger...) to assemble to generate model-based control schemes. Every component is described by its algebraic or differential equation and can be assembled with others to build the dynamical model of a complete refrigerator or the model of a subpart of it. The obtained model can be used to automatically design advanced model based control scheme. It also can be used to design a model based PI controller. Advanced control schemes aim to replace classical user experience designed approaches usually based on many independent PI controllers. This is particularly useful in the case where cryoplants are submitted to large pulsed thermal loads, expected to take place in future fusion reactors such as those expected in the cryogenic cooling systems of the International Thermonuclear Experimental Reactor (ITER) or the Japan Torus-60 Super Advanced Fusion Experiment (JT- 60SA). The paper gives the example of the generation of the dynamical model of the 400W@1.8K refrigerator and shows how to build a Constrained Model Predictive Control for it. Based on the scheme, experimental results will be given. This work is being supported by the French national research agency (ANR) through the ANR-13-SEED-0005 CRYOGREEN program.

CRBRP modular steam generator tube-to-tubesheet and shell-closure welding

DOE Office of Scientific and Technical Information (OSTI.GOV)

Viri, D.P.

1982-01-01

The original Modular Steam Generator (MSG), whiand inh was designed, built, and tested by the Energy Systems Group (ESG) of Rockwell International, was a departure from conventional boilers or heat exchangers. The design was a hockeystick concept - the upper section of the generator is curved 90/sup 0/. Factors affecting operating parameters were considered and incorporated in the original MSG design. The MSG was fully instrumented and functionally tested at the Energy Technology Engineering Center at Rockwell. The MSG steamed continuously for over 4000 h, and at the conclusion of the 9000-h test cycle, it was systematically dismantled and examinedmore » for wear to critical components. This paper explains the solutions to several manufacturing challenges presented by the unique design of the MSG.« less

Shuttle/ISS EMU Failure History and the Impact on Advanced EMU Portable Life Support System (PLSS) Design

NASA Technical Reports Server (NTRS)

Campbell, Colin

2015-01-01

As the Shuttle/ISS EMU Program exceeds 35 years in duration and is still supporting the needs of the International Space Station (ISS), a critical benefit of such a long running program with thorough documentation of system and component failures is the ability to study and learn from those failures when considering the design of the next generation space suit. Study of the subject failure history leads to changes in the Advanced EMU Portable Life Support System (PLSS) schematic, selected component technologies, as well as the planned manner of ground testing. This paper reviews the Shuttle/ISS EMU failure history and discusses the implications to the AEMU PLSS.

Shuttle/ISS EMU Failure History and the Impact on Advanced EMU PLSS Design

NASA Technical Reports Server (NTRS)

Campbell, Colin

2011-01-01

As the Shuttle/ISS EMU Program exceeds 30 years in duration and is still successfully supporting the needs of the International Space Station (ISS), a critical benefit of such a long running program with thorough documentation of system and component failures is the ability to study and learn from those failures when considering the design of the next generation space suit. Study of the subject failure history leads to changes in the Advanced EMU Portable Life Support System (PLSS) schematic, selected component technologies, as well as the planned manner of ground testing. This paper reviews the Shuttle/ISS EMU failure history and discusses the implications to the AEMU PLSS.

Shuttle/ISS EMU Failure History and the Impact on Advanced EMU PLSS Design

NASA Technical Reports Server (NTRS)

Campbell, Colin

2015-01-01

As the Shuttle/ISS EMU Program exceeds 30 years in duration and is still supporting the needs of the International Space Station (ISS), a critical benefit of such a long running program with thorough documentation of system and component failures is the ability to study and learn from those failures when considering the design of the next generation space suit. Study of the subject failure history leads to changes in the Advanced EMU Portable Life Support System (PLSS) schematic, selected component technologies, as well as the planned manner of ground testing. This paper reviews the Shuttle/ISS EMU failure history and discusses the implications to the AEMU PLSS.

Improved spin squeezing of an atomic ensemble through internal state control

NASA Astrophysics Data System (ADS)

Hemmer, Daniel; Montano, Enrique; Deutsch, Ivan; Jessen, Poul

2016-05-01

Squeezing of collective atomic spins is typically generated by quantum backaction from a QND measurement of the relevant spin component. In this scenario the degree of squeezing is determined by the measurement resolution relative to the quantum projection noise (QPN) of a spin coherent state (SCS). Greater squeezing can be achieved through optimization of the 3D geometry of probe and atom cloud, or by placing the atoms in an optical cavity. We explore here a complementary strategy that relies on quantum control of the large internal spin available in alkali atoms such as Cs. Using a combination of rf and uw magnetic fields, we coherently map the internal spins in our ensemble from the SCS (| f = 4, m = 4>) to a ``cat'' state which is an equal superposition of | f = 4, m = 4>and | f = 4, m = -4>. This increases QPN by a factor of 2 f = 8 relative to the SCS, and therefore the amount of backaction and spin-spin entanglement produced by our QND measurement. In a final step, squeezing generated in the cat state basis can be mapped back to the SCS basis, where it corresponds to increased squeezing of the physical spin. Our experiments suggest that up to 8dB of metrologically useful squeezing can be generated in this way, compared to ~ 3 dB in an otherwise identical experiment starting from a SCS.

Interactive Light Stimulus Generation with High Performance Real-Time Image Processing and Simple Scripting.

PubMed

Szécsi, László; Kacsó, Ágota; Zeck, Günther; Hantz, Péter

2017-01-01

Light stimulation with precise and complex spatial and temporal modulation is demanded by a series of research fields like visual neuroscience, optogenetics, ophthalmology, and visual psychophysics. We developed a user-friendly and flexible stimulus generating framework (GEARS GPU-based Eye And Retina Stimulation Software), which offers access to GPU computing power, and allows interactive modification of stimulus parameters during experiments. Furthermore, it has built-in support for driving external equipment, as well as for synchronization tasks, via USB ports. The use of GEARS does not require elaborate programming skills. The necessary scripting is visually aided by an intuitive interface, while the details of the underlying software and hardware components remain hidden. Internally, the software is a C++/Python hybrid using OpenGL graphics. Computations are performed on the GPU, and are defined in the GLSL shading language. However, all GPU settings, including the GPU shader programs, are automatically generated by GEARS. This is configured through a method encountered in game programming, which allows high flexibility: stimuli are straightforwardly composed using a broad library of basic components. Stimulus rendering is implemented solely in C++, therefore intermediary libraries for interfacing could be omitted. This enables the program to perform computationally demanding tasks like en-masse random number generation or real-time image processing by local and global operations.

Generation of tunable infrared radiation by stimulated Raman scattering on hydrogen in a prism-lens optical delay line

NASA Astrophysics Data System (ADS)

Andreev, R. B.; Butylkin, V. S.; Evtiushkin, V. A.; Fisher, P. S.; Khabarov, V. V.

1983-03-01

The threshold of stimulated Raman scattering was lowered by filling an optical delay line with hydrogen. Pumping was by a tunable neodymium laser. Lens-prism combinations were used as phase correctors in the delay line. The dependences of the energy of the Stokes component on the pump energy determined experimentally for different numbers of transits through the delay line were compared with the results of a calculation allowing for the losses in the components of this line. When the frequency conversion was by a factor of at least 2 and the tuning range was wide (tens of percent), the optimal performance was obtained from the optical delay line when total-internal-reflection prisms and lenses were combined in a single component and oriented at the Brewster angle.

BRIEF COMMUNICATIONS: Generation of tunable infrared radiation by stimulated Raman scattering on hydrogen in a prism-lens optical delay line

NASA Astrophysics Data System (ADS)

Andreev, R. B.; Butylkin, V. S.; Evtyushkin, V. A.; Fisher, P. S.; Khabarov, V. V.

1983-03-01

The threshold of stimulated Raman scattering was lowered by filling an optical delay line with hydrogen. Pumping was by a tunable neodymium laser. Lens-prism combinations were used as phase correctors in the delay line. The dependences of the energy of the Stokes component on the pump energy determined experimentally for different numbers of transits through the delay line were compared with the results of a calculation allowing for the losses in the components of this line. When the frequency conversion was by a factor of at least 2 and the tuning range was wide (tens of percent), the optimal performance was obtained from the optical delay line when total-internal-reflection prisms and lenses were combined in a single component and oriented at the Brewster angle.

Membrane Assembly during the Infection Cycle of the Giant Mimivirus

PubMed Central

Mutsafi, Yael; Shimoni, Eyal; Shimon, Amir; Minsky, Abraham

2013-01-01

Although extensively studied, the structure, cellular origin and assembly mechanism of internal membranes during viral infection remain unclear. By combining diverse imaging techniques, including the novel Scanning-Transmission Electron Microscopy tomography, we elucidate the structural stages of membrane biogenesis during the assembly of the giant DNA virus Mimivirus. We show that this elaborate multistage process occurs at a well-defined zone localized at the periphery of large viral factories that are generated in the host cytoplasm. Membrane biogenesis is initiated by fusion of multiple vesicles, ∼70 nm in diameter, that apparently derive from the host ER network and enable continuous supply of lipid components to the membrane-assembly zone. The resulting multivesicular bodies subsequently rupture to form large open single-layered membrane sheets from which viral membranes are generated. Membrane generation is accompanied by the assembly of icosahedral viral capsids in a process involving the hypothetical major capsid protein L425 that acts as a scaffolding protein. The assembly model proposed here reveals how multiple Mimivirus progeny can be continuously and efficiently generated and underscores the similarity between the infection cycles of Mimivirus and Vaccinia virus. Moreover, the membrane biogenesis process indicated by our findings provides new insights into the pathways that might mediate assembly of internal viral membranes in general. PMID:23737745

Efficient nonlinear optical conversion of 1.319-micron laser radiation

NASA Astrophysics Data System (ADS)

Byer, Robert L.; Eckardt, Robert C.

1993-01-01

The accomplishments of this program are in the development and application of periodically poled nonlinear optical materials for nonlinear frequency-conversion. We have demonstrated the use of periodically poled lithium niobate (PPLN) as a bulk material for external resonant cavity second-harmonic generation with continuous-wave (cw) output power of 1.7 W. Work that is following this investigation is showing that planar waveguides of PPLN may well be the most satisfactory method of generation of 10's of mW of the 659-nm harmonic of the 1.32-micrometer Nd:YAG laser. We encountered major obstacles obtaining multilayer dielectric coatings necessary to pursue our proposed design of monolithic bulk optical harmonic generators. Additional alternative approaches such as discrete component resonant second harmonic generation employing single domain and periodically poled bulk crystals and monolithic single domain resonators formed by total internal reflection remain under investigation.

Numerical analysis of internal solitary wave generation around a Island in Kuroshio Current using MITgcm.

NASA Astrophysics Data System (ADS)

Kodaira, Tsubasa; Waseda, Takuji

2013-04-01

We have conducted ADCP and CTD measurements from 31/8/2010 to 2/9/2010 at the Miyake Island, located approximately 180 km south of Tokyo. The Kuroshio Current approached the island in this period, and the PALSAR image showed parabolic bright line upstream of the island. This bright line may be a surface signature of large amplitude internal solitary wave. Although our measurements did not explicitly show evidence of the internal solitary wave, critical condition might have been satisfied because of the Kuroshio Current and strong seasonal thermocline. To discover the generation mechanism of the large amplitude internal solitary wave at the Miyake Island, we have conducted non-hydrostatic numerical simulation with the MITgcm. A simple box domain, with open boundaries at all sides, is used. The island is simplified to circular cylinder or Gaussian Bell whose radius is 3km at ocean surface level. The size of the domain is 40kmx40kmx500m for circular cylinder cases and 80kmx80kmx500m for Gaussian bell cases. By looking at our CTD data, we have chosen for initial and boundary conditions a tanh function for vertical temperature profile. Salinity was kept constant for simplicity. Vertical density profile is also described by tanh function because we adopt linear type of equation of state. Vertical velocity profile is constant or linearly changed with depth; the vertical mean speed corresponds to the linear phase speed of the first baroclinic mode obtained by solving the eigen-value problem. With these configurations, we have conducted two series of simulations: shear flow through cylinder and uniform flow going through Gaussian Bell topography. Internal solitary waves were generated in front of the cylinder for the first series of simulations with shear flow. The generated internal waves almost purely consisted of 1st baroclinic component. Their intensities were linearly related with upstream vertical shear strength. As the internal solitary wave became larger, its width became wider compared to the KdV solution described by Grimshaw (2002). This is predicted because higher order analytical solution for 2-layer fluids, i.e. the eKdV solution, gives broader solitary wave shape than that of the KdV solution because of the cubic nonlinear term. When we look at the surface velocity distribution, a parabolic shape corresponding to internal solitary wave is clearly seen. According to the fully nonlinear theoretical model for internal wave between two fluids having background linear shear flow profiles (Choi and Camassa1999), the shape of internal wave is influenced by the velocity shear as well. However, we could not clarify the effect of vertical shear because there is no fully nonlinear analytical solution for large amplitude internal wave in continuously stratified fluid. Second series of simulations with uniform flow going through Gaussian Bell topography show that internal solitary wave shows up from sides of the topography. This generation is similar to the one developed in lee side of sill topography by tidal flow. With broader bell topography, generated internal waves become larger. This makes sense because forcing region is wider. A horizontal shape of the internal solitary wave is not parabolic but the two bending line forms from the sides of the island. However, no solitary wave in front of the island develops. Our results imply that vertical shear profile is needed for the formation of the depression type internal solitary, and explains the parabolic bright line observed in the SAR image

International standards in mitigating trade risks.

PubMed

Thiermann, A B

2011-04-01

This paper describes the role of the World Organisation for Animal Health (OIE), as a science-based and democratic standard-setting organisation that provides guidance on preventing the spread of animal diseases, including zoonoses, in international trade. The World Trade Organization is identified as the international institution with the legal power to encourage adherence to international standards and mediate trade disputes. The importance of assuring good governance and the credibility of national Veterinary Services through a process of official certification is identified as an essential component in the safety of trade. Private-public partnerships and the evolution of responsibilities are also identified as essential for the implementation of health guarantees such as compartmentalisation. The rapid emergence of private standards is described as a potential complement to the implementation of sanitary standards, as long as they are applied globally and in support of the OIE standards. Ultimately, the biggest challenge is for the international community to create the incentives and generate the political will for fair trade and for the universal recognition and application of the established international sanitary standards.

Effect of EHR user interface changes on internal prescription discrepancies.

PubMed

Turchin, A; Sawarkar, A; Dementieva, Y A; Breydo, E; Ramelson, H

2014-01-01

To determine whether specific design interventions (changes in the user interface (UI)) of an electronic health record (EHR) medication module are associated with an increase or decrease in the incidence of contradictions between the structured and narrative components of electronic prescriptions (internal prescription discrepancies). We performed a retrospective analysis of 960,000 randomly selected electronic prescriptions generated in a single EHR between 01/2004 and 12/2011. Internal prescription discrepancies were identified using a validated natural language processing tool with recall of 76% and precision of 84%. A multivariable autoregressive integrated moving average (ARIMA) model was used to evaluate the effect of five UI changes in the EHR medication module on incidence of internal prescription discrepancies. Over the study period 175,725 (18.4%) prescriptions were found to have internal discrepancies. The highest rate of prescription discrepancies was observed in March 2006 (22.5%) and the lowest in March 2009 (15.0%). Addition of "as directed" option to the dropdown decreased prescription discrepancies by 195 / month (p = 0.0004). An non-interruptive alert that reminded providers to ensure that structured and narrative components did not contradict each other decreased prescription discrepancies by 145 / month (p = 0.03). Addition of a "Renew / Sign" button to the Medication module (a negative control) did not have an effect in prescription discrepancies. Several UI changes in the electronic medication module were effective in reducing the incidence of internal prescription discrepancies. Further research is needed to identify interventions that can completely eliminate this type of prescription error and their effects on patient outcomes.

FFT-enhanced IHS transform method for fusing high-resolution satellite images

USGS Publications Warehouse

Ling, Y.; Ehlers, M.; Usery, E.L.; Madden, M.

2007-01-01

Existing image fusion techniques such as the intensity-hue-saturation (IHS) transform and principal components analysis (PCA) methods may not be optimal for fusing the new generation commercial high-resolution satellite images such as Ikonos and QuickBird. One problem is color distortion in the fused image, which causes visual changes as well as spectral differences between the original and fused images. In this paper, a fast Fourier transform (FFT)-enhanced IHS method is developed for fusing new generation high-resolution satellite images. This method combines a standard IHS transform with FFT filtering of both the panchromatic image and the intensity component of the original multispectral image. Ikonos and QuickBird data are used to assess the FFT-enhanced IHS transform method. Experimental results indicate that the FFT-enhanced IHS transform method may improve upon the standard IHS transform and the PCA methods in preserving spectral and spatial information. ?? 2006 International Society for Photogrammetry and Remote Sensing, Inc. (ISPRS).

Dynamic Analysis and Test Results for an STC Stirling Generator

NASA Astrophysics Data System (ADS)

Qiu, Songgang; Peterson, Allen A.

2004-02-01

Long-life, high-efficiency generators based on free-piston Stirling machines are a future energy-conversion solution for both space and commercial applications. To aid in design and system integration efforts, Stirling Technology Company (STC) has developed dynamic simulation models for the internal moving subassemblies and for complete Stirling convertor assemblies. These dynamic models have been validated using test data from operating prototypes. Simplified versions of these models are presented to help explain the operating characteristics of the Stirling convertor. Power spectrum analysis is presented for the test data for casing acceleration, piston motion, displacer motion, and controller current/voltage during full power operation. The harmonics of a Stirling convertor and its moving components are identified for the STC zener-diode control scheme. The dynamic behavior of each moving component and its contribution to the system dynamics and resultant vibration forces are discussed. Additionally, the effects of a passive balancer and external suspension are predicted by another simplified system model.

Scanning of the internal structure part with laser ultrasonic in aviation industry.

PubMed

Swornowski, Pawel J

2011-01-01

The detection of internal defects is a major production and safety issue for the newest generations of aircraft. New materials and manufacturing processes in the aircraft industry demand efficient quality assurance in manufacturing and inspection in maintenance. Advanced metallic material processes (titanium) are used or developed for the production of heavily loaded flying components (in fan blade construction). The inspection of these parts mainly made out of titanium (or CFRP) requires the determination of the percentage of bonded grain sizes around 10-30 µm. This is primarily due to the advantages of a high signal-to-noise ratio and good detection sensitivity. In this article, a diagnosing method of the blade interior by means of the laser ultrasonic is presented. Identification of small fatigue cracks presents a challenging problem during nondestructive testing of fatigue-damaged structures. Laser ultrasonic is a technique that uses two laser beams; one with a short pulse for the generation of ultrasound and another with a long pulse or continuous coupled to an optical interferometer for detection. The results of research of the internal blade structure are presented. Copyright © 2011 Wiley Periodicals, Inc.

A Data Management System for International Space Station Simulation Tools

NASA Technical Reports Server (NTRS)

Betts, Bradley J.; DelMundo, Rommel; Elcott, Sharif; McIntosh, Dawn; Niehaus, Brian; Papasin, Richard; Mah, Robert W.; Clancy, Daniel (Technical Monitor)

2002-01-01

Groups associated with the design, operational, and training aspects of the International Space Station make extensive use of modeling and simulation tools. Users of these tools often need to access and manipulate large quantities of data associated with the station, ranging from design documents to wiring diagrams. Retrieving and manipulating this data directly within the simulation and modeling environment can provide substantial benefit to users. An approach for providing these kinds of data management services, including a database schema and class structure, is presented. Implementation details are also provided as a data management system is integrated into the Intelligent Virtual Station, a modeling and simulation tool developed by the NASA Ames Smart Systems Research Laboratory. One use of the Intelligent Virtual Station is generating station-related training procedures in a virtual environment, The data management component allows users to quickly and easily retrieve information related to objects on the station, enhancing their ability to generate accurate procedures. Users can associate new information with objects and have that information stored in a database.

A principal component analysis of the relationship between the external body shape and internal skeleton for the upper body.

PubMed

Nerot, A; Skalli, W; Wang, X

2016-10-03

Recent progress in 3D scanning technologies allows easy access to 3D human body envelope. To create personalized human models with an articulated linkage for realistic re-posturing and motion analyses, an accurate estimation of internal skeleton points, including joint centers, from the external envelope is required. For this research project, 3D reconstructions of both internal skeleton and external envelope from low dose biplanar X-rays of 40 male adults were obtained. Using principal component analysis technique (PCA), a low-dimensional dataset was used to predict internal points of the upper body from the trunk envelope. A least squares method was used to find PC scores that fit the PCA-based model to the envelope of a new subject. To validate the proposed approach, estimated internal points were evaluated using a leave-one-out (LOO) procedure, i.e. successively considering each individual from our dataset as an extra-subject. In addition, different methods were proposed to reduce the variability in data and improve the performance of the PCA-based prediction. The best method was considered as the one providing the smallest errors between estimated and reference internal points with an average error of 8.3mm anterior-posteriorly, 6.7mm laterally and 6.5mm vertically. As the proposed approach relies on few or no bony landmarks, it could be easily applicable and generalizable to surface scans from any devices. Combined with automatic body scanning techniques, this study could potentially constitute a new step towards automatic generation of external/internal subject-specific manikins. Copyright © 2016 Elsevier Ltd. All rights reserved.

Oxygen Generation System Laptop Bus Controller Flight Software

NASA Technical Reports Server (NTRS)

Rowe, Chad; Panter, Donna

2009-01-01

The Oxygen Generation System Laptop Bus Controller Flight Software was developed to allow the International Space Station (ISS) program to activate specific components of the Oxygen Generation System (OGS) to perform a checkout of key hardware operation in a microgravity environment, as well as to perform preventative maintenance operations of system valves during a long period of what would otherwise be hardware dormancy. The software provides direct connectivity to the OGS Firmware Controller with pre-programmed tasks operated by on-orbit astronauts to exercise OGS valves and motors. The software is used to manipulate the pump, separator, and valves to alleviate the concerns of hardware problems due to long-term inactivity and to allow for operational verification of microgravity-sensitive components early enough so that, if problems are found, they can be addressed before the hardware is required for operation on-orbit. The decision was made to use existing on-orbit IBM ThinkPad A31p laptops and MIL-STD-1553B interface cards as the hardware configuration. The software at the time of this reporting was developed and tested for use under the Windows 2000 Professional operating system to ensure compatibility with the existing on-orbit computer systems.

Advanced Space Transportation Program (ASTP)

NASA Image and Video Library

2002-10-01

NASA's Marshall Space Flight Center in Huntsville, Alabama, manages the Space Launch Initiative (SLI), NASA's priority developmental program focused on empowering America's leadership in space. SLI includes commercial, higher education, and Defense partnerships and contracts to offer widespread participation in both the risk and success of developing our nation's next-generation reusable launch vehicle. This photo depicts an artist's concept of a future second-generation launch vehicle enroute to the International Space Station. For the SLI, architecture definition includes all components of the next-generation reusable launch system: Earth-to-orbit vehicles (the Space Shuttle is the first generation earth-to-orbit vehicle), crew transfer vehicles, transfer stages, ground processing systems, flight operations systems, and development of business case strategies. Three contractor teams have each been funded to develop potential second-generation reusable launch system architectures: The Boeing Company of Seal Beach, California; Lockheed Martin Corporation of Denver, Colorado along with a team including Northrop Grumman of El Segundo, California; and Orbital Sciences Corporation of Dulles, Virginia.

A two-channel action-potential generator for testing neurophysiologic data acquisition/analysis systems.

PubMed

Lisiecki, R S; Voigt, H F

1995-08-01

A 2-channel action-potential generator system was designed for use in testing neurophysiologic data acquisition/analysis systems. The system consists of a personal computer controlling an external hardware unit. This system is capable of generating 2 channels of simulated action potential (AP) waveshapes. The AP waveforms are generated from the linear combination of 2 principal-component template functions. Each channel generates randomly occurring APs with a specified rate ranging from 1 to 200 events per second. The 2 trains may be independent of one another or the second channel may be made to be excited or inhibited by the events from the first channel with user-specified probabilities. A third internal channel may be made to excite or inhibit events in both of the 2 output channels with user-specified rate parameters and probabilities. The system produces voltage waveforms that may be used to test neurophysiologic data acquisition systems for recording from 2 spike trains simultaneously and for testing multispike-train analysis (e.g., cross-correlation) software.

SLI Artist's Concept-Vehicle Enroute to Space Station

NASA Technical Reports Server (NTRS)

2002-01-01

NASA's Marshall Space Flight Center in Huntsville, Alabama, manages the Space Launch Initiative (SLI), NASA's priority developmental program focused on empowering America's leadership in space. SLI includes commercial, higher education, and Defense partnerships and contracts to offer widespread participation in both the risk and success of developing our nation's next-generation reusable launch vehicle. This photo depicts an artist's concept of a future second-generation launch vehicle enroute to the International Space Station. For the SLI, architecture definition includes all components of the next-generation reusable launch system: Earth-to-orbit vehicles (the Space Shuttle is the first generation earth-to-orbit vehicle), crew transfer vehicles, transfer stages, ground processing systems, flight operations systems, and development of business case strategies. Three contractor teams have each been funded to develop potential second-generation reusable launch system architectures: The Boeing Company of Seal Beach, California; Lockheed Martin Corporation of Denver, Colorado along with a team including Northrop Grumman of El Segundo, California; and Orbital Sciences Corporation of Dulles, Virginia.

Motion at the Tibial and Polyethylene Component Interface in a Mobile-Bearing Total Ankle Replacement.

PubMed

Lundeen, Gregory A; Clanton, Thomas O; Dunaway, Linda J; Lu, Minggen

2016-08-01

Normal biomechanics of the ankle joint includes sagittal as well as axial rotation. Current understanding of mobile-bearing motion at the tibial-polyethylene interface in total ankle arthroplasty (TAA) is limited to anterior-posterior (AP) motion of the polyethylene component. The purpose of our study was to define the motion of the polyethylene component in relation to the tibial component in a mobile-bearing TAA in both the sagittal and axial planes in postoperative patients. Patients who were a minimum of 12 months postoperative from a third-generation mobile-bearing TAA were identified. AP images were saved at maximum internal and external rotation, and the lateral images were saved in maximum plantarflexion and dorsiflexion. Sagittal range of motion and AP translation of the polyethylene component were measured from the lateral images. Axial rotation was determined by measuring the relative position of the 2 wires within the polyethylene component on AP internal and external rotation imaging. This relationship was compared to a table developed from fluoroscopic images taken at standardized degrees of axial rotation of a nonimplanted polyethylene with the associated length relationship of the 2 imbedded wires. Sixteen patients were included in this investigation, 9 (56%) were male and average age was 68 (range, 49-80) years. Time from surgery averaged 25 (range, 12-38) months. Total sagittal range of motion averaged 23±9 (range, 9-33) degrees. Axial motion for total internal and external rotation of the polyethylene component on the tibial component averaged 6±5 (range, 0-18) degrees. AP translation of the polyethylene component relative to the tibial component averaged 1±1 (range, 0-3) mm. There was no relationship between axial rotation or AP translation of the polyethylene component and ankle joint range of motion (P > .05). To our knowledge, this is the first investigation to measure axial and sagittal motion of the polyethylene component at the tibial implant interface in patients following a mobile-bearing TAA. Based on outcome scores and range-of-motion measurements, we believe the patients in this study are a representative cross section of subjects compared to other TAA research results. The results from this investigation indicate the potential for a mobile-bearing TAA to fall within the parameters of normal polyaxial ankle motion. The multiplanar articulation in a mobile-bearing TAA may reduce excessively high peak pressures during the complex dynamic tibial and talar motion, which may have a positive influence on gait pattern, polyethylene wear, and implant longevity. Level IV, case series. © The Author(s) 2016.

Computer-Aided Design of Low-Noise Microwave Circuits

NASA Astrophysics Data System (ADS)

Wedge, Scott William

1991-02-01

Devoid of most natural and manmade noise, microwave frequencies have detection sensitivities limited by internally generated receiver noise. Low-noise amplifiers are therefore critical components in radio astronomical antennas, communications links, radar systems, and even home satellite dishes. A general technique to accurately predict the noise performance of microwave circuits has been lacking. Current noise analysis methods have been limited to specific circuit topologies or neglect correlation, a strong effect in microwave devices. Presented here are generalized methods, developed for computer-aided design implementation, for the analysis of linear noisy microwave circuits comprised of arbitrarily interconnected components. Included are descriptions of efficient algorithms for the simultaneous analysis of noisy and deterministic circuit parameters based on a wave variable approach. The methods are therefore particularly suited to microwave and millimeter-wave circuits. Noise contributions from lossy passive components and active components with electronic noise are considered. Also presented is a new technique for the measurement of device noise characteristics that offers several advantages over current measurement methods.

Perspectives on Permanent Magnetic Materials for Energy Conversion and Power Generation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lewis, LH; Jimenez-Villacorta, F

2012-07-18

Permanent magnet development has historically been driven by the need to supply larger magnetic energy in ever smaller volumes for incorporation in an enormous variety of applications that include consumer products, transportation components, military hardware, and clean energy technologies such as wind turbine generators and hybrid vehicle regenerative motors. Since the 1960s, the so-called rare-earth "supermagnets," composed of iron, cobalt, and rare-earth elements such as Nd, Pr, and Sm, have accounted for the majority of global sales of high-energy-product permanent magnets for advanced applications. In rare-earth magnets, the transition-metal components provide high magnetization, and the rare-earth components contribute a verymore » large magnetocrystalline anisotropy that donates high resistance to demagnetization. However, at the end of 2009, geopolitical influences created a worldwide strategic shortage of rare-earth elements that may be addressed, among other actions, through the development of rare-earth-free magnetic materials harnessing sources of magnetic anisotropy other than that provided by the rare-earth components. Materials engineering at the micron scale, nanoscale, and Angstrom scales, accompanied by improvements in the understanding and characterization of nanoscale magnetic phenomena, is anticipated to result in new types of permanent magnetic materials with superior performance. DOI: 10.1007/s11661-012-1278-2 (C) The Minerals, Metals & Materials Society and ASM International 2012« less

Grid-independent residential power systems

NASA Astrophysics Data System (ADS)

Nelson, Robert E.

1996-02-01

A self-powered, gas-fired, warm air furnace is evaluated as a candidate for the autonomous generation of electrical power. A popular, commercial residential furnace is analyzed for electrical power requirements. Available energy conversion concepts are considered for this application, and the thermophotovoltaic (TPV) option is selected due to reliability and cost. The design and the internal components peculiar to the TPV converter will be covered. Operating results, including NOx emission, will be summarized. This work was sponsored by the Basic Research Group, Gas Research Institute, Chicago, IL.

Proceedings of the International Conference on High-Power Particle Beams (12th) Held in Haifa, Israel on June 7-12, 1998. Volume 1

DTIC Science & Technology

1998-06-12

Bucharest, Romania 257 TO THE THEORY OF A PLASMA FILLED ION DIODE L.I. Rudakov, RRC Kurchatov Institute, Moscow, Russia, A.S. Chuvatin, Ecole...B. Moosman, S.J. Stephanakis, Naval Research Laboratory, Washington DC, USA 306 -XVII- PLASMA EVOLUTION OF A POS: COMPARISON OF THEORY AND...POSs. INTRODUCTION The POS is a critical component of the multi-module DECADE generator.’ At present, maximum bremsstrahlung is produced on DECADE Module

IEEE International Symposium Information Theory, held at Santa Monica California, February 9-12, 1981.

DTIC Science & Technology

1981-01-01

Channel and study permutation codes as a special case. ,uch a code is generated by an initial vector x, a group G of orthogonal n by n matrices, and a...random-access components, is introduced and studied . Under this scheme, the network stations are divided into groups , each of which is assigned a...IEEE INFORMATION THEORY GROUP CO-SPONSORED BY: UNION RADIO SCIENTIFIQUE INTERNATIONALE IEEE Catalog Number 81 CH 1609-7 IT 𔃻. 81 ~20 04Q SECURITY

A Design Basis for Spacecraft Cabin Trace Contaminant Control

NASA Technical Reports Server (NTRS)

Perry, Jay L.

2009-01-01

Successful trace chemical contamination control is one of the components necessary for achieving good cabin atmospheric quality. While employing seemingly simple process technologies, sizing the active contamination control equipment must employ a reliable design basis for the trace chemical load in the cabin atmosphere. A simplified design basis that draws on experience gained from the International Space Station program is presented. The trace chemical contamination control design load refines generation source magnitudes and includes key chemical functional groups representing both engineering and toxicology challenges.

Structural mechanics simulations

NASA Technical Reports Server (NTRS)

Biffle, Johnny H.

1992-01-01

Sandia National Laboratory has a very broad structural capability. Work has been performed in support of reentry vehicles, nuclear reactor safety, weapons systems and components, nuclear waste transport, strategic petroleum reserve, nuclear waste storage, wind and solar energy, drilling technology, and submarine programs. The analysis environment contains both commercial and internally developed software. Included are mesh generation capabilities, structural simulation codes, and visual codes for examining simulation results. To effectively simulate a wide variety of physical phenomena, a large number of constitutive models have been developed.

Point process models for localization and interdependence of punctate cellular structures.

PubMed

Li, Ying; Majarian, Timothy D; Naik, Armaghan W; Johnson, Gregory R; Murphy, Robert F

2016-07-01

Accurate representations of cellular organization for multiple eukaryotic cell types are required for creating predictive models of dynamic cellular function. To this end, we have previously developed the CellOrganizer platform, an open source system for generative modeling of cellular components from microscopy images. CellOrganizer models capture the inherent heterogeneity in the spatial distribution, size, and quantity of different components among a cell population. Furthermore, CellOrganizer can generate quantitatively realistic synthetic images that reflect the underlying cell population. A current focus of the project is to model the complex, interdependent nature of organelle localization. We built upon previous work on developing multiple non-parametric models of organelles or structures that show punctate patterns. The previous models described the relationships between the subcellular localization of puncta and the positions of cell and nuclear membranes and microtubules. We extend these models to consider the relationship to the endoplasmic reticulum (ER), and to consider the relationship between the positions of different puncta of the same type. Our results do not suggest that the punctate patterns we examined are dependent on ER position or inter- and intra-class proximity. With these results, we built classifiers to update previous assignments of proteins to one of 11 patterns in three distinct cell lines. Our generative models demonstrate the ability to construct statistically accurate representations of puncta localization from simple cellular markers in distinct cell types, capturing the complex phenomena of cellular structure interaction with little human input. This protocol represents a novel approach to vesicular protein annotation, a field that is often neglected in high-throughput microscopy. These results suggest that spatial point process models provide useful insight with respect to the spatial dependence between cellular structures. © 2016 International Society for Advancement of Cytometry. © 2016 International Society for Advancement of Cytometry.

Assuring long-term reliability of concentrator PV systems

NASA Astrophysics Data System (ADS)

McConnell, R.; Garboushian, V.; Brown, J.; Crawford, C.; Darban, K.; Dutra, D.; Geer, S.; Ghassemian, V.; Gordon, R.; Kinsey, G.; Stone, K.; Turner, G.

2009-08-01

Concentrator PV (CPV) systems have attracted significant interest because these systems incorporate the world's highest efficiency solar cells and they are targeting the lowest cost production of solar electricity for the world's utility markets. Because these systems are just entering solar markets, manufacturers and customers need to assure their reliability for many years of operation. There are three general approaches for assuring CPV reliability: 1) field testing and development over many years leading to improved product designs, 2) testing to internationally accepted qualification standards (especially for new products) and 3) extended reliability tests to identify critical weaknesses in a new component or design. Amonix has been a pioneer in all three of these approaches. Amonix has an internal library of field failure data spanning over 15 years that serves as the basis for its seven generations of CPV systems. An Amonix product served as the test CPV module for the development of the world's first qualification standard completed in March 2001. Amonix staff has served on international standards development committees, such as the International Electrotechnical Commission (IEC), in support of developing CPV standards needed in today's rapidly expanding solar markets. Recently Amonix employed extended reliability test procedures to assure reliability of multijunction solar cell operation in its seventh generation high concentration PV system. This paper will discuss how these three approaches have all contributed to assuring reliability of the Amonix systems.

International Space Station (ISS)

NASA Image and Video Library

2000-01-01

This diagram shows the flow of recyclable resources in the International Space Station (ISS). The Environmental Control and Life Support System (ECLSS) Group of the Flight Projects Directorate at the Marshall Space Flight Center is responsible for the regenerative ECLSS hardware, as well as providing technical support for the rest of the system. The regenerative ECLSS, whose main components are the Water Recovery System (WRS), and the Oxygen Generation System (OGS), reclaims and recycles water and oxygen. The ECLSS maintains a pressurized habitation environment, provides water recovery and storage, maintains and provides fire detection / suppression, and provides breathable air and a comfortable atmosphere in which to live and work within the ISS. The ECLSS hardware will be located in the Node 3 module of the ISS.

International Space Station (ISS)

NASA Image and Video Library

2000-01-01

This diagram shows the flow of water recovery and management in the International Space Station (ISS). The Environmental Control and Life Support System (ECLSS) Group of the Flight Projects Directorate at the Marshall Space Flight Center is responsible for the regenerative ECLSS hardware, as well as providing technical support for the rest of the system. The regenerative ECLSS, whose main components are the Water Recovery System (WRS), and the Oxygen Generation System (OGS), reclaims and recycles water oxygen. The ECLSS maintains a pressurized habitation environment, provides water recovery and storage, maintains and provides fire detection/ suppression, and provides breathable air and a comfortable atmosphere in which to live and work within the ISS. The ECLSS hardware will be located in the Node 3 module of the ISS.

Ethical challenges for international collaborative research partnerships in the context of the Zika outbreak in the Dominican Republic: a qualitative case study.

PubMed

Canario Guzmán, Julio Arturo; Espinal, Roberto; Báez, Jeannette; Melgen, Ricardo Elias; Rosario, Patricia Antonia Pérez; Mendoza, Eddys Rafael

2017-09-25

The establishment of international collaborative research partnerships in times of infectious disease outbreaks of international importance has been considered an ethical imperative. Frail health research systems in low- and middle-income countries can be an obstacle to achieve the goal of knowledge generation and the search for health equity before, during and after infectious disease outbreaks. A qualitative case study was conducted to identify the challenges and opportunities facing the Dominican Republic with regards to developing international collaborative research partnerships in the context of the Zika outbreak and its ethical implications. Researchers conducted 34 interviews (n = 30 individual; n = 4 group) with 39 participants (n = 23 males; n = 16 females) representing the government, universities, international donor agencies, non-governmental organisations, community-based organisations and medical societies, in two metropolitan cities. Five international collaborative research projects related to the Zika virus were identified. Major ethical challenges were linked to the governance of health research, training of human resources, the institutionalisation of scientific activity, access to research funds and cultural aspects. Capacity-building was not necessarily a component of some partnership agreements. With few exceptions, local researchers were merely participating in data collection and less on defining the problem. Opportunities for collaborative work included the possibility of participation in international research consortiums through calls for proposals. The Dominican government and research stakeholders can contribute to the international response to the Zika virus through active participation in international collaborative research partnerships; however, public recognition of the need to embrace health research as part of public policy efforts is warranted. A working group led by the government and formed by national and international research stakeholders will be key to identify ways in which the country could respond to the ethical demand of generating new knowledge in times of outbreaks.

International Heliophysical Year

NASA Technical Reports Server (NTRS)

Davila, Joseph, M.

2005-01-01

The International Heliophysical Year (IHY), an international program of scientific collaboration to understand the external drivers of planetary environments, will be conducted in 2007. This will be a major international event of great interest to the member States. The M Y will involve the deployment of new instrumentation, new observations from the ground and in space, and an education component. The IHY 2007 will coincide with the fiftieth anniversary of the International Geophysical Year (IGY) in 1957. The IGY was organized to study global phenomena of the Earth and Geospace involving about 60,000 scientists from 66 nations, working at thousands of stations, around the world to obtain simultaneous, global observations from the ground and space. Building on results obtained during IGY 1957, the IHY will expand to the study of universal processes in the solar system that affect the interplanetary and terrestrial environments. The study of energetic events in the solar system will pave the way for safe human space travel to the Moon and planets in the future, and it will serve to inspire the next generation of space physicists.

Plans for the International Heliophysical Year (IHY)

NASA Technical Reports Server (NTRS)

Davila, Joseph M.; Thompson, Barbara J.; Gopalswamy, Nat

2005-01-01

The International Heliophysical Year (IHY), an international program of scientific collaboration to understand the external drivers of planetary environments, will be conducted in 2007. This will be a major international event of great interest to the member States. The IHY will involve the deployment of new instrumentation, new observations from the ground and in space, and an education component. The IHY 2007 will coincide with the fiftieth anniversary of the International Geophysical Year (IGY) in 1957. The IGY was organized to study global phenomena of the Earth and Geospace involving about thousands of scientists from many nations, working at thousands of stations, around the world to obtain simultaneous, global observations from the ground and space. Building on results obtained during IGY 1957, the IHY will expand to the study of universal processes in the solar system that affect the interplanetary and terrestrial environments. The study of energetic events in the solar system will pave the way for safe human space travel to the Moon and planets in the future, and it will serve to inspire the next generation of space physicists.

DNA-histone complexes as ligands amplify cell penetration and nuclear targeting of anti-DNA antibodies via energy-independent mechanisms.

PubMed

Zannikou, Markella; Bellou, Sofia; Eliades, Petros; Hatzioannou, Aikaterini; Mantzaris, Michael D; Carayanniotis, George; Avrameas, Stratis; Lymberi, Peggy

2016-01-01

We have generated three monoclonal cell-penetrating antibodies (CPAbs) from a non-immunized lupus-prone (NZB × NZW)F1 mouse that exhibited high anti-DNA serum titres. These CPAbs are polyreactive because they bind to DNA and other cellular components, and localize mainly in the nucleus of HeLa cells, albeit with a distinct nuclear labelling profile. Herein, we have examined whether DNA-histone complexes (DHC) binding to CPAbs, before cell entry, could modify the cell penetration of CPAbs or their nuclear staining properties. By applying confocal microscopy and image analysis, we found that extracellular binding of purified CPAbs to DHC significantly enhanced their subsequent cell-entry, both in terms of percentages of positively labelled cells and fluorescence intensity (internalized CPAb amount), whereas there was a variable effect on their nuclear staining profile. Internalization of CPAbs, either alone or bound to DHC, remained unaltered after the addition of endocytosis-specific inhibitors at 37° or assay performance at 4°, suggesting the involvement of energy-independent mechanisms in the internalization process. These findings assign to CPAbs a more complex pathogenetic role in systemic lupus erythematosus where both CPAbs and nuclear components are abundant. © 2015 John Wiley & Sons Ltd.

Virtual reality for intelligent and interactive operating, training, and visualization systems

NASA Astrophysics Data System (ADS)

Freund, Eckhard; Rossmann, Juergen; Schluse, Michael

2000-10-01

Virtual Reality Methods allow a new and intuitive way of communication between man and machine. The basic idea of Virtual Reality (VR) is the generation of artificial computer simulated worlds, which the user not only can look at but also can interact with actively using data glove and data helmet. The main emphasis for the use of such techniques at the IRF is the development of a new generation of operator interfaces for the control of robots and other automation components and for intelligent training systems for complex tasks. The basic idea of the methods developed at the IRF for the realization of Projective Virtual Reality is to let the user work in the virtual world as he would act in reality. The user actions are recognized by the Virtual reality System and by means of new and intelligent control software projected onto the automation components like robots which afterwards perform the necessary actions in reality to execute the users task. In this operation mode the user no longer has to be a robot expert to generate tasks for robots or to program them, because intelligent control software recognizes the users intention and generated automatically the commands for nearly every automation component. Now, Virtual Reality Methods are ideally suited for universal man-machine-interfaces for the control and supervision of a big class of automation components, interactive training and visualization systems. The Virtual Reality System of the IRF-COSIMIR/VR- forms the basis for different projects starting with the control of space automation systems in the projects CIROS, VITAL and GETEX, the realization of a comprehensive development tool for the International Space Station and last but not least with the realistic simulation fire extinguishing, forest machines and excavators which will be presented in the final paper in addition to the key ideas of this Virtual Reality System.

Small, modular, low-cost coal-fired power plants for the international market

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zauderer, B.; Frain, B.; Borck, B.

1997-12-31

This paper presents recent operating results of Coal Tech`s second generation, air cooled, slagging coal combustor, and its application to power plants in the 1 to 20 MW range. This 20 MMBtu/hour combustor was installed in a new demonstration plant in Philadelphia, PA in 1995. It contains the combustion components of a 1 MWe coal fired power plant, a 17,500 lb/hour steam boiler, coal storage and feed components, and stack gas cleanup components. The plant`s design incorporates improvements resulting from 2,000 hours of testing between 1987 and 1993 on a first generation, commercial scale, air cooled combustor of equal thermalmore » rating. Since operations began in early 1996, a total of 51 days of testing have been successfully completed. Major results include durability of the combustor`s refractory wall, excellent combustion with high ash concentration in the fuel, removal of 95% to 100% of the slag in the combustor, very little ash deposition in the boiler, major reduction of in-plant parasitic power, and simplified power system control through the use of modular designs of sub-systems and computer control. Rapid fuel switching between oil, gas, and coal and turndown of up to a factor of three was accomplished. All these features have been incorporated in advanced coal fired plant designs in the 1 to 20 MWe range. Incremental capital costs are only $100 to $200/kW higher than comparable rated gas or oil fired steam generating systems. Most of its components and subsystems can be factory assembled for very rapid field installation. The low capital, low operating costs, fuel flexibility, and compatibility with very high ash fuels, make this power system very attractive in regions of the world having domestic supplies of these fuels.« less

A Timer for Synchronous Digital Systems

NASA Technical Reports Server (NTRS)

McKenney, Elizabeth; Irwin, Philip

2003-01-01

The Real-Time Interferometer Control Systems Testbed (RICST) timing board is a VersaModule Eurocard (VME)-based board that can generate up to 16 simultaneous, phase-locked timing signals at a rate defined by the user. It can also generate all seven VME interrupt requests (IRQs). The RICST timing board is suitable mainly for robotic, aerospace, and real-time applications. Several circuit boards on the market are capable of generating periodic IRQs. Most are associated with Global Positioning System (GPS) receivers and Inter Range Instrumentation Group (IRIG) time-code generators, whereas this board uses either an internal VME clock or an externally generated clock signal to synchronize multiple components of the system. The primary advantage of this board is that there is no discernible jitter in the output clock waveforms because the signals are divided down from a high-frequency clock signal instead of being phase-locked from a lower frequency. The primary disadvantage to this board, relative to other periodic-IRQ-generating boards, is that it is more difficult to synchronize the system to wall clock time.

Effect of EHR User Interface Changes on Internal Prescription Discrepancies

PubMed Central

Sawarkar, A.; Dementieva, Y.A.; Breydo, E.; Ramelson, H.

2014-01-01

Summary Objective To determine whether specific design interventions (changes in the user interface (UI)) of an electronic health record (EHR) medication module are associated with an increase or decrease in the incidence of contradictions between the structured and narrative components of electronic prescriptions (internal prescription discrepancies). Materials and Methods We performed a retrospective analysis of 960,000 randomly selected electronic prescriptions generated in a single EHR between 01/2004 and 12/2011. Internal prescription discrepancies were identified using a validated natural language processing tool with recall of 76% and precision of 84%. A multivariable autoregressive integrated moving average (ARIMA) model was used to evaluate the effect of five UI changes in the EHR medication module on incidence of internal prescription discrepancies. Results Over the study period 175,725 (18.4%) prescriptions were found to have internal discrepancies. The highest rate of prescription discrepancies was observed in March 2006 (22.5%) and the lowest in March 2009 (15.0%). Addition of „as directed“ option to the dropdown decreased prescription discrepancies by 195 / month (p = 0.0004). An non-interruptive alert that reminded providers to ensure that structured and narrative components did not contradict each other decreased prescription discrepancies by 145 / month (p = 0.03). Addition of a „Renew / Sign“ button to the Medication module (a negative control) did not have an effect in prescription discrepancies. Conclusions Several UI changes in the electronic medication module were effective in reducing the incidence of internal prescription discrepancies. Further research is needed to identify interventions that can completely eliminate this type of prescription error and their effects on patient outcomes. PMID:25298811

Interactive Light Stimulus Generation with High Performance Real-Time Image Processing and Simple Scripting

PubMed Central

Szécsi, László; Kacsó, Ágota; Zeck, Günther; Hantz, Péter

2017-01-01

Light stimulation with precise and complex spatial and temporal modulation is demanded by a series of research fields like visual neuroscience, optogenetics, ophthalmology, and visual psychophysics. We developed a user-friendly and flexible stimulus generating framework (GEARS GPU-based Eye And Retina Stimulation Software), which offers access to GPU computing power, and allows interactive modification of stimulus parameters during experiments. Furthermore, it has built-in support for driving external equipment, as well as for synchronization tasks, via USB ports. The use of GEARS does not require elaborate programming skills. The necessary scripting is visually aided by an intuitive interface, while the details of the underlying software and hardware components remain hidden. Internally, the software is a C++/Python hybrid using OpenGL graphics. Computations are performed on the GPU, and are defined in the GLSL shading language. However, all GPU settings, including the GPU shader programs, are automatically generated by GEARS. This is configured through a method encountered in game programming, which allows high flexibility: stimuli are straightforwardly composed using a broad library of basic components. Stimulus rendering is implemented solely in C++, therefore intermediary libraries for interfacing could be omitted. This enables the program to perform computationally demanding tasks like en-masse random number generation or real-time image processing by local and global operations. PMID:29326579

77 FR 16270 - Updated Aging Management Criteria for Reactor Vessel Internal Components of Pressurized Water...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-20

... NUCLEAR REGULATORY COMMISSION [NRC-2012-0070] Updated Aging Management Criteria for Reactor Vessel Internal Components of Pressurized Water Reactors AGENCY: Nuclear Regulatory Commission. ACTION: Draft..., ``Updated Aging Management Criteria for PWR Reactor Vessel Internal Components.'' This draft LR-ISG revises...

77 FR 23513 - Updated Aging Management Criteria for Reactor Vessel Internal Components of Pressurized Water...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-19

... NUCLEAR REGULATORY COMMISSION [NRC-2012-0070] Updated Aging Management Criteria for Reactor Vessel Internal Components of Pressurized Water Reactors AGENCY: Nuclear Regulatory Commission. ACTION: Draft...-ISG), LR-ISG-2011-04, ``Updated Aging Management Criteria for PWR Reactor Vessel Internal Components...

Performance Evaluation of the International Space Station Flow Boiling and Condensation Experiment (FBCE) Test Facility

NASA Technical Reports Server (NTRS)

Hasan, Mohammad; Balasubramaniam, R.; Nahra, Henry; Mackey, Jeff; Hall, Nancy; Frankenfield, Bruce; Harpster, George; May, Rochelle; Mudawar, Issam; Kharangate, Chirag R.;

Software design and code generation for the engineering graphical user interface of the ASTRI SST-2M prototype for the Cherenkov Telescope Array

NASA Astrophysics Data System (ADS)

Tanci, Claudio; Tosti, Gino; Antolini, Elisa; Gambini, Giorgio F.; Bruno, Pietro; Canestrari, Rodolfo; Conforti, Vito; Lombardi, Saverio; Russo, Federico; Sangiorgi, Pierluca; Scuderi, Salvatore

2016-08-01

ASTRI is an on-going project developed in the framework of the Cherenkov Telescope Array (CTA). An end- to-end prototype of a dual-mirror small-size telescope (SST-2M) has been installed at the INAF observing station on Mt. Etna, Italy. The next step is the development of the ASTRI mini-array composed of nine ASTRI SST-2M telescopes proposed to be installed at the CTA southern site. The ASTRI mini-array is a collaborative and international effort carried on by Italy, Brazil and South-Africa and led by the Italian National Institute of Astrophysics, INAF. To control the ASTRI telescopes, a specific ASTRI Mini-Array Software System (MASS) was designed using a scalable and distributed architecture to monitor all the hardware devices for the telescopes. Using code generation we built automatically from the ASTRI Interface Control Documents a set of communication libraries and extensive Graphical User Interfaces that provide full access to the capabilities offered by the telescope hardware subsystems for testing and maintenance. Leveraging these generated libraries and components we then implemented a human designed, integrated, Engineering GUI for MASS to perform the verification of the whole prototype and test shared services such as the alarms, configurations, control systems, and scientific on-line outcomes. In our experience the use of code generation dramatically reduced the amount of effort in development, integration and testing of the more basic software components and resulted in a fast software release life cycle. This approach could be valuable for the whole CTA project, characterized by a large diversity of hardware components.

One way Doppler Extractor. Volume 2: Digital VCO technique

NASA Technical Reports Server (NTRS)

Nossen, E. J.; Starner, E. R.

1974-01-01

A feasibility analysis and trade-offs for a one-way Doppler extractor using digital VCO techniques is presented. The method of Doppler measurement involves the use of a digital phase lock loop; once this loop is locked to the incoming signal, the precise frequency and hence the Doppler component can be determined directly from the contents of the digital control register. The only serious error source is due to internally generated noise. Techniques are presented for minimizing this error source and achieving an accuracy of 0.01 Hz in a one second averaging period. A number of digitally controlled oscillators were analyzed from a performance and complexity point of view. The most promising technique uses an arithmetic synthesizer as a digital waveform generator.

Development of a Versatile Ultrasonic Internal Pipe/Vessel Component Monitor for In-Service Inspection of Nuclear Reactor Components

DOE Office of Scientific and Technical Information (OSTI.GOV)

Searfass, Clifford T.; Malinowski, Owen M.; Van Velsor, Jason K.

2015-03-22

The stated goal of this work was to develop a versatile system which could accurately measure vessel and valve internal vibrations and cavitation formation under in-service conditions in nuclear power plants, ultrasonically. The developed technology will benefit the nuclear power generation industry by allowing plant operators to monitor valve and vessel internals during operation. This will help reduce planned outages and plant component failures. During the course of this work, Structural Integrity Associates, Inc. gathered information from industry experts that target vibration amplitudes to be detected should be in the range of 0.001-in to 0.005-in (0.025-mm to 0.127-mm) and targetmore » vibration frequency ranges which should be detected were found to be between 0-Hz and 300-Hz. During the performed work, an ultrasonic measuring system was developed which utilized ultrasonic pulse-echo time-of-flight measurements to measure vibration frequency and amplitude. The developed system has been shown to be able to measure vibration amplitudes as low as 0.0008-in (0.020-mm) with vibration frequencies in the range of 17-Hz to 1000-Hz. Therefore, the developed system was able to meet the industry needs for vibration measurement. The developed ultrasonic system was also to be able to measure cavitation formation by monitoring the received ultrasonic time- and frequency-domain signals. This work also demonstrated the survivability of commercially available probes at temperatures up to 300-F for several weeks.« less

The dynamics of contract plasma fractionation.

PubMed

Farrugia, Albert; Scaramuccia, Daniela

2017-03-01

Plasma Derived Medicinal Products (PMDPs) are an essential component of the modern therapeutic armamentarium. They are differentiated from most other medicines in several ways, particularly the unique nature of the raw material used for their manufacture. Human plasma has been fractionated to PDMPs for the past 75 years, and the economics of manufacturing requires currently that as many products are harvested from each litre as is feasible and reflective of clinical needs. PDMPs may be purchased on the open market from the various commercial and not-for-profit (NFP) manufacturers. They may also be manufactured under contract (CM) from plasma supplied by government and similar agencies as a product of blood transfusion services. Clients for CM aspire to make full use of donated plasma, hence maximizing the donors' gift after the standard components of transfusion have been harvested. Many such countries also aspire to making their national clinical needs self-sufficient in PDMPs, attempting to acquire strategic independence from the vagaries of the commercial open market. The increasing commercial imperatives operating in the PMDP sector generate a tension with such ethical aspirations which are not easily resolved. In particular, the need to harvest as many proteins as possible may generate products which are surplus to national needs, necessitating an ethical paradigm for the optimal provision of such products. In addition, traditional relationships between blood services and domestic fractionation agencies may come under stress as a result of the competitive processes underpinning such transactions, which are now subject to international norms of free trade. Blood services engaged in the supply of hospital transfusion components are detached from the pharmaceutical Good Manufacturing Practices (GMP) culture needed for the production of plasma for CM, while the generation of such plasma through extraction from whole blood donations deflects the focus from that of a dedicated raw material for CM to a byproduct of the donation process. We review the field of CM, assess the current tensions within the sector, and offer suggestions for the strategic positioning of governments and other clients to ensure optimal outcomes for all the stakeholders involved. Copyright © 2017 International Alliance for Biological Standardization. Published by Elsevier Ltd. All rights reserved.

Light Microscopy Module Fan Disturbance Characterized Through Microgravity Emissions Laboratory Testing

NASA Technical Reports Server (NTRS)

McNelis, Anne M.; Motil, Susan M.

2003-01-01

A Light Microscopy Module (LMM) is being engineered, designed, and developed at the NASA Glenn Research Center. The LMM is planned as a remotely controllable on-orbit microscope subrack facility, allowing flexible scheduling and control of physical science and biological science experiments within Glenn s Fluids Integrated Rack on the International Space Station. The LMM concept is a modified commercial research imaging light microscope with powerful laser-diagnostic hardware and interfaces, creating a one-of-a-kind, state-of-the-art microscopic research facility. The microscope will house several different objectives, corresponding to magnifications of 10, 40, 50, 63, and 100. Features of the LMM include high-resolution color video microscopy, brightfield, darkfield, phase contrast, differential interference contrast, spectrophotometry, and confocal microscopy combined in a single configuration. Also, laser tweezers are integrated with the diagnostics as a sample manipulation technique. As part of the development phase of the LMM, it was necessary to quantify the microgravity disturbances generated by the control box fan. Isolating the fan was deemed necessary to reduce the fan speed harmonic amplitudes and to eliminate any broadband disturbances across the 60- to 70-Hz and 160- to 170-Hz frequency ranges. The accelerations generated by a control box fan component of the LMM were measured in the Microgravity Emissions Laboratory (MEL). The MEL is a low-frequency measurement system developed to simulate and verify the on-orbit International Space Station (ISS) microgravity environment. The accelerations generated by various operating components of the ISS, if too large, could hinder the science performed onboard by disturbing the microgravity environment. The MEL facility gives customers a test-verified way of measuring their compliance with ISS limitations on vibratory disturbance levels. The facility is unique in that inertial forces in 6 degrees of freedom can be characterized simultaneously for an operating test article. Vibratory disturbance levels are measured for engineering or flight-level hardware following development from component to subassembly through the rack-level configuration. The MEL can measure accelerations as small as 10-7g, the accuracy needed to confirm compliance with ISS requirements.

Modal Survey of ETM-3, A 5-Segment Derivative of the Space Shuttle Solid Rocket Booster

NASA Technical Reports Server (NTRS)

Nielsen, D.; Townsend, J.; Kappus, K.; Driskill, T.; Torres, I.; Parks, R.

2005-01-01

The complex interactions between internal motor generated pressure oscillations and motor structural vibration modes associated with the static test configuration of a Reusable Solid Rocket Motor have potential to generate significant dynamic thrust loads in the 5-segment configuration (Engineering Test Motor 3). Finite element model load predictions for worst-case conditions were generated based on extrapolation of a previously correlated 4-segment motor model. A modal survey was performed on the largest rocket motor to date, Engineering Test Motor #3 (ETM-3), to provide data for finite element model correlation and validation of model generated design loads. The modal survey preparation included pretest analyses to determine an efficient analysis set selection using the Effective Independence Method and test simulations to assure critical test stand component loads did not exceed design limits. Historical Reusable Solid Rocket Motor modal testing, ETM-3 test analysis model development and pre-test loads analyses, as well as test execution, and a comparison of results to pre-test predictions are discussed.

77 FR 17093 - Certain Food Waste Disposers and Components and Packaging Thereof: Notice of Receipt of Complaint...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-23

... INTERNATIONAL TRADE COMMISSION [DN 2886] Certain Food Waste Disposers and Components and Packaging...: U.S. International Trade Commission. ACTION: Notice. SUMMARY: Notice is hereby given that the U.S. International Trade Commission has received a complaint entitled Certain Food Waste Disposers and Components and...

Elongated Nanoparticle Aggregates in Cancer Cells for Mechanical Destruction with Low Frequency Rotating Magnetic Field.

PubMed

Shen, Yajing; Wu, Congyu; Uyeda, Taro Q P; Plaza, Gustavo R; Liu, Bin; Han, Yu; Lesniak, Maciej S; Cheng, Yu

2017-01-01

Magnetic nanoparticles (MNPs) functionalized with targeting moieties can recognize specific cell components and induce mechanical actuation under magnetic field. Their size is adequate for reaching tumors and targeting cancer cells. However, due to the nanometric size, the force generated by MNPs is smaller than the force required for largely disrupting key components of cells. Here, we show the magnetic assembly process of the nanoparticles inside the cells, to form elongated aggregates with the size required to produce elevated mechanical forces. We synthesized iron oxide nanoparticles doped with zinc, to obtain high magnetization, and functionalized with the epidermal growth factor (EGF) peptide for targeting cancer cells. Under a low frequency rotating magnetic field at 15 Hz and 40 mT, the internalized EGF-MNPs formed elongated aggregates and generated hundreds of pN to dramatically damage the plasma and lysosomal membranes. The physical disruption, including leakage of lysosomal hydrolases into the cytosol, led to programmed cell death and necrosis. Our work provides a novel strategy of designing magnetic nanomedicines for mechanical destruction of cancer cells.

An evaluation of the nursing practice environment and successful change management using the new generation Magnet Model.

PubMed

Grant, Bettyanne; Colello, Sandra; Riehle, Martha; Dende, Denise

2010-04-01

To discuss the new Magnet Model as it relates to the successful implementation of a practice change. There is growing international interest in the Magnet Recognition Programme. The latest generation of the Magnet Model has been designed not only as a road map for organizations seeking to achieve Magnet recognition but also as a framework for nursing practice and research in the future. The Magnet Model was used to identify success factors related to a practice change and to evaluate the nursing practice environment. Even when proposed changes to practice are evidence based and thoughtfully considered, the nurses' work environment must be supportive and empowering in order to yield successful and sustainable implementation of new practice. Success factors for implementation of a practice change can be illuminated by aligning environmental characteristics to the components of the new Magnet Model. The Magnet Model provides an exceptional framework for building an agile and dynamic work force. Thoughtful consideration of the components and inter-relationships represented in the new model can help to both predict and ensure organizational vitality.

Elongated Nanoparticle Aggregates in Cancer Cells for Mechanical Destruction with Low Frequency Rotating Magnetic Field

PubMed Central

Shen, Yajing; Wu, Congyu; Uyeda, Taro Q. P.; Plaza, Gustavo R.; Liu, Bin; Han, Yu; Lesniak, Maciej S.; Cheng, Yu

2017-01-01

Magnetic nanoparticles (MNPs) functionalized with targeting moieties can recognize specific cell components and induce mechanical actuation under magnetic field. Their size is adequate for reaching tumors and targeting cancer cells. However, due to the nanometric size, the force generated by MNPs is smaller than the force required for largely disrupting key components of cells. Here, we show the magnetic assembly process of the nanoparticles inside the cells, to form elongated aggregates with the size required to produce elevated mechanical forces. We synthesized iron oxide nanoparticles doped with zinc, to obtain high magnetization, and functionalized with the epidermal growth factor (EGF) peptide for targeting cancer cells. Under a low frequency rotating magnetic field at 15 Hz and 40 mT, the internalized EGF-MNPs formed elongated aggregates and generated hundreds of pN to dramatically damage the plasma and lysosomal membranes. The physical disruption, including leakage of lysosomal hydrolases into the cytosol, led to programmed cell death and necrosis. Our work provides a novel strategy of designing magnetic nanomedicines for mechanical destruction of cancer cells. PMID:28529648

Characteristics of the Swirling Flow Generated by an Axial Swirler

NASA Technical Reports Server (NTRS)

Fu, Yongqiang; Jeng, San-Mou; Tacina, Robert

2005-01-01

An experimental investigation was conducted to study the aerodynamic characteristics of the confined, non-reacting, swirling flow field. The flow was generated by a helicoidal axial-vaned swirler with a short internal convergent-divergent venturi, which was confined within 2-inch square test section. A series of helicoidal axial-vaned swirlers have been designed with tip vane angles of 40 deg., 45 deg., 50 deg., 55 deg., 60 deg. and 65 deg.. The swirler with the tip vane angle of 60 deg. was combined with several simulated fuel nozzle insertions of varying lengths. A two-component Laser Doppler Velocimetry (LDV) system was employed to measure the three-component mean velocities and Reynolds stresses. Detailed data are provided to enhance understanding swirling flow with different swirl degrees and geometries and to support the development of more accurate physicaVnumerica1 models. The data indicated that the degree of swirl had a clear impact on the mean and turbulent flow fields. The swirling flow fields changed significantly with the addition of a variety of simulated fuel nozzle insertion lengths

HiMoP: A three-component architecture to create more human-acceptable social-assistive robots : Motivational architecture for assistive robots.

PubMed

Rodríguez-Lera, Francisco J; Matellán-Olivera, Vicente; Conde-González, Miguel Á; Martín-Rico, Francisco

2018-05-01

Generation of autonomous behavior for robots is a general unsolved problem. Users perceive robots as repetitive tools that do not respond to dynamic situations. This research deals with the generation of natural behaviors in assistive service robots for dynamic domestic environments, particularly, a motivational-oriented cognitive architecture to generate more natural behaviors in autonomous robots. The proposed architecture, called HiMoP, is based on three elements: a Hierarchy of needs to define robot drives; a set of Motivational variables connected to robot needs; and a Pool of finite-state machines to run robot behaviors. The first element is inspired in Alderfer's hierarchy of needs, which specifies the variables defined in the motivational component. The pool of finite-state machine implements the available robot actions, and those actions are dynamically selected taking into account the motivational variables and the external stimuli. Thus, the robot is able to exhibit different behaviors even under similar conditions. A customized version of the "Speech Recognition and Audio Detection Test," proposed by the RoboCup Federation, has been used to illustrate how the architecture works and how it dynamically adapts and activates robots behaviors taking into account internal variables and external stimuli.

Next Generation Trusted Radiation Identification System (NG-TRIS).

DOE Office of Scientific and Technical Information (OSTI.GOV)

Flynn, Adam J.; Amai, Wendy A.; Merkle, Peter Benedict

2010-05-01

The original Trusted Radiation Identification System (TRIS) was developed from 1999-2001, featuring information barrier technology to collect gamma radiation template measurements useful for arms control regime operations. The first TRIS design relied upon a multichannel analyzer (MCA) that was external to the protected volume of the system enclosure, undesirable from a system security perspective. An internal complex programmable logic device (CPLD) contained data which was not subject to software authentication. Physical authentication of the TRIS instrument case was performed by a sensitive but slow eddy-current inspection method. This paper describes progress to date for the Next Generation TRIS (NG-TRIS), whichmore » improves the TRIS design. We have incorporated the MCA internal to the trusted system volume, achieved full authentication of CPLD data, and have devised rapid methods to authenticate the system enclosure and weld seals of the NG-TRIS enclosure. For a complete discussion of the TRIS system and components upon which NG-TRIS is based, the reader is directed to the comprehensive user's manual and system reference of Seager, et al.« less

Energy input and response from prompt and early optical afterglow emission in gamma-ray bursts.

PubMed

Vestrand, W T; Wren, J A; Wozniak, P R; Aptekar, R; Golentskii, S; Pal'shin, V; Sakamoto, T; White, R R; Evans, S; Casperson, D; Fenimore, E

2006-07-13

The taxonomy of optical emission detected during the critical first few minutes after the onset of a gamma-ray burst (GRB) defines two broad classes: prompt optical emission correlated with prompt gamma-ray emission, and early optical afterglow emission uncorrelated with the gamma-ray emission. The standard theoretical interpretation attributes prompt emission to internal shocks in the ultra-relativistic outflow generated by the internal engine; early afterglow emission is attributed to shocks generated by interaction with the surrounding medium. Here we report on observations of a bright GRB that, for the first time, clearly show the temporal relationship and relative strength of the two optical components. The observations indicate that early afterglow emission can be understood as reverberation of the energy input measured by prompt emission. Measurements of the early afterglow reverberations therefore probe the structure of the environment around the burst, whereas the subsequent response to late-time impulsive energy releases reveals how earlier flaring episodes have altered the jet and environment parameters. Many GRBs are generated by the death of massive stars that were born and died before the Universe was ten per cent of its current age, so GRB afterglow reverberations provide clues about the environments around some of the first stars.

Using diagnostic experiences in experience-based innovative design

NASA Astrophysics Data System (ADS)

Prabhakar, Sattiraju; Goel, Ashok K.

1992-03-01

Designing a novel class of devices requires innovation. Often, the design knowledge of these devices does not identify and address the constraints that are required for their performance in the real world operating environment. So any new design adapted from these devices tend to be similarly sketchy. In order to address this problem, we propose a case-based reasoning method called performance driven innovation (PDI). We model the design as a dynamic process, arrive at a design by adaptation from the known designs, generate failures for this design for some new constraints, and then use this failure knowledge to generate the required design knowledge for the new constraints. In this paper, we discuss two aspects of PDI: the representation of PDI cases and the translation of the failure knowledge into design knowledge for a constraint. Each case in PDI has two components: design and failure knowledge. Both of them are represented using a substance-behavior-function model. Failure knowledge has internal device failure behaviors and external environmental behaviors. The environmental behavior, for a constraint, interacting with the design behaviors, results in the failure internal behavior. The failure adaptation strategy generates functions, from the failure knowledge, which can be addressed using the routine design methods. These ideas are illustrated using a coffee-maker example.

Toward Development of a Stochastic Wake Model: Validation Using LES and Turbine Loads

DOE PAGES

Moon, Jae; Manuel, Lance; Churchfield, Matthew; ...

2017-12-28

Wind turbines within an array do not experience free-stream undisturbed flow fields. Rather, the flow fields on internal turbines are influenced by wakes generated by upwind unit and exhibit different dynamic characteristics relative to the free stream. The International Electrotechnical Commission (IEC) standard 61400-1 for the design of wind turbines only considers a deterministic wake model for the design of a wind plant. This study is focused on the development of a stochastic model for waked wind fields. First, high-fidelity physics-based waked wind velocity fields are generated using Large-Eddy Simulation (LES). Stochastic characteristics of these LES waked wind velocity field,more » including mean and turbulence components, are analyzed. Wake-related mean and turbulence field-related parameters are then estimated for use with a stochastic model, using Multivariate Multiple Linear Regression (MMLR) with the LES data. To validate the simulated wind fields based on the stochastic model, wind turbine tower and blade loads are generated using aeroelastic simulation for utility-scale wind turbine models and compared with those based directly on the LES inflow. The study's overall objective is to offer efficient and validated stochastic approaches that are computationally tractable for assessing the performance and loads of turbines operating in wakes.« less

Toward Development of a Stochastic Wake Model: Validation Using LES and Turbine Loads

DOE Office of Scientific and Technical Information (OSTI.GOV)

Moon, Jae; Manuel, Lance; Churchfield, Matthew

Wind turbines within an array do not experience free-stream undisturbed flow fields. Rather, the flow fields on internal turbines are influenced by wakes generated by upwind unit and exhibit different dynamic characteristics relative to the free stream. The International Electrotechnical Commission (IEC) standard 61400-1 for the design of wind turbines only considers a deterministic wake model for the design of a wind plant. This study is focused on the development of a stochastic model for waked wind fields. First, high-fidelity physics-based waked wind velocity fields are generated using Large-Eddy Simulation (LES). Stochastic characteristics of these LES waked wind velocity field,more » including mean and turbulence components, are analyzed. Wake-related mean and turbulence field-related parameters are then estimated for use with a stochastic model, using Multivariate Multiple Linear Regression (MMLR) with the LES data. To validate the simulated wind fields based on the stochastic model, wind turbine tower and blade loads are generated using aeroelastic simulation for utility-scale wind turbine models and compared with those based directly on the LES inflow. The study's overall objective is to offer efficient and validated stochastic approaches that are computationally tractable for assessing the performance and loads of turbines operating in wakes.« less

2nd & 3rd Generation Vehicle Subsystems

NASA Technical Reports Server (NTRS)

2000-01-01

This paper contains viewgraph presentation on the "2nd & 3rd Generation Vehicle Subsystems" project. The objective behind this project is to design, develop and test advanced avionics, power systems, power control and distribution components and subsystems for insertion into a highly reliable and low-cost system for a Reusable Launch Vehicles (RLV). The project is divided into two sections: 3rd Generation Vehicle Subsystems and 2nd Generation Vehicle Subsystems. The following topics are discussed under the first section, 3rd Generation Vehicle Subsystems: supporting the NASA RLV program; high-performance guidance & control adaptation for future RLVs; Evolvable Hardware (EHW) for 3rd generation avionics description; Scaleable, Fault-tolerant Intelligent Network or X(trans)ducers (SFINIX); advance electric actuation devices and subsystem technology; hybrid power sources and regeneration technology for electric actuators; and intelligent internal thermal control. Topics discussed in the 2nd Generation Vehicle Subsystems program include: design, development and test of a robust, low-maintenance avionics with no active cooling requirements and autonomous rendezvous and docking systems; design and development of a low maintenance, high reliability, intelligent power systems (fuel cells and battery); and design of a low cost, low maintenance high horsepower actuation systems (actuators).

Diagram of the Water Recovery and Management for the International Space Station

NASA Technical Reports Server (NTRS)

2000-01-01

This diagram shows the flow of water recovery and management in the International Space Station (ISS). The Environmental Control and Life Support System (ECLSS) Group of the Flight Projects Directorate at the Marshall Space Flight Center is responsible for the regenerative ECLSS hardware, as well as providing technical support for the rest of the system. The regenerative ECLSS, whose main components are the Water Recovery System (WRS), and the Oxygen Generation System (OGS), reclaims and recycles water oxygen. The ECLSS maintains a pressurized habitation environment, provides water recovery and storage, maintains and provides fire detection/ suppression, and provides breathable air and a comfortable atmosphere in which to live and work within the ISS. The ECLSS hardware will be located in the Node 3 module of the ISS.

Laboratory information management system: an example of international cooperation in Namibia.

PubMed

Colangeli, Patrizia; Ferrilli, Monica; Quaranta, Fabrizio; Malizia, Elio; Mbulu, Rosa-Stella; Mukete, Esther; Iipumbu, Lukas; Kamhulu, Anna; Tjipura-Zaire, Georgina; Di Francesco, Cesare; Lelli, Rossella; Scacchia, Massimo

2012-01-01

The authors describe the project undertaken by the Istituto G. Caporale to provide a laboratory information management system (LIMS) to the Central Veterinary Laboratory (CVL) in Windhoek, Namibia. This robust laboratory management tool satisfies Namibia's information obligations under international quality standard ISO 17025:2005. The Laboratory Information Management System (LIMS) for Africa was designed to collect and manage all necessary information on samples, tests and test results. The system involves the entry of sample data on arrival, as required by Namibian sampling plans, the tracking of samples through the various sections of the CVL, the collection of test results, generation of test reports and monitoring of outbreaks through data interrogation functions, eliminating multiple registrations of the same data on paper records. It is a fundamental component of the Namibian veterinary information system.

Fusion Materials Research at Oak Ridge National Laboratory in Fiscal Year 2014

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wiffen, Frederick W.; Noe, Susan P.; Snead, Lance Lewis

2014-10-01

The realization of fusion energy is a formidable challenge with significant achievements resulting from close integration of the plasma physics and applied technology disciplines. Presently, the most significant technological challenge for the near-term experiments such as ITER, and next generation fusion power systems, is the inability of current materials and components to withstand the harsh fusion nuclear environment. The overarching goal of the ORNL fusion materials program is to provide the applied materials science support and understanding to underpin the ongoing DOE Office of Science fusion energy program while developing materials for fusion power systems. In doing so the programmore » continues to be integrated both with the larger U.S. and international fusion materials communities, and with the international fusion design and technology communities.« less

Evidence from numerical experiments for a feedback dynamo generating Mercury's magnetic field.

PubMed

Heyner, Daniel; Wicht, Johannes; Gómez-Pérez, Natalia; Schmitt, Dieter; Auster, Hans-Ulrich; Glassmeier, Karl-Heinz

2011-12-23

The observed weakness of Mercury's magnetic field poses a long-standing puzzle to dynamo theory. Using numerical dynamo simulations, we show that it could be explained by a negative feedback between the magnetospheric and the internal magnetic fields. Without feedback, a small internal field was amplified by the dynamo process up to Earth-like values. With feedback, the field strength saturated at a much lower level, compatible with the observations at Mercury. The classical saturation mechanism via the Lorentz force was replaced by the external field impact. The resulting surface field was dominated by uneven harmonic components. This will allow the feedback model to be distinguished from other models once a more accurate field model is constructed from MErcury Surface, Space ENvironment, GEochemistry, and Ranging (MESSENGER) and BepiColombo data.

Influence of Component Rotation in Total Knee Arthroplasty on Tibiofemoral Kinematics-A Cadaveric Investigation.

PubMed

Maderbacher, Guenther; Keshmiri, Armin; Springorum, Hans R; Maderbacher, Hermann; Grifka, Joachim; Baier, Clemens

2017-09-01

Physiological tibiofemoral kinematics have been shown to be important for good knee function after total knee arthroplasty (TKA). The purpose of the present study was to investigate the influence of component rotation on tibiofemoral kinematics during knee flexion. We asked which axial component alignment best reconstructs physiological tibiofemoral kinematics and which combinations should be avoided. Ten healthy cadaveric knees were examined. By means of a navigational device, tibiofemoral kinematics between 0° and 90° of flexion were assessed before and after TKA using the following different rotational component alignment: femoral components: ligament balanced, 6° internal, 3° external rotation, and 6° external rotation in relation to the posterior condylar line; tibial components: self-adapted, 6° internal rotation, and 6° external rotation. Physiological tibiofemoral kinematics could be partly reconstructed by TKA. Ligament-balanced femoral rotation and 6° femoral external rotation both in combination with 6° tibial component external rotation, and 3° femoral external rotation in combination with 6° tibial component internal rotation or self-aligning tibial component were able to restore tibial longitudinal rotation. Largest kinematical differences were found for the combination femoral component internal and tibial component external rotations. From a kinematic-based view, surgeons should avoid internal rotation of femoral components. However, even often recommended combinations of rotational component alignment (3° femoral external and tibial external rotation) significantly change tibiofemoral kinematics. Self-aligning tibial components solely restored tibiofemoral kinematics with the combination of 3° femoral component of external rotation. For the future, navigational devices might help to axially align components to restore patient-specific and natural tibiofemoral kinematics. Copyright © 2017 Elsevier Inc. All rights reserved.

Computational Fluid Dynamics Symposium on Aeropropulsion

NASA Technical Reports Server (NTRS)

1991-01-01

Recognizing the considerable advances that have been made in computational fluid dynamics, the Internal Fluid Mechanics Division of NASA Lewis Research Center sponsored this symposium with the objective of providing a forum for exchanging information regarding recent developments in numerical methods, physical and chemical modeling, and applications. This conference publication is a compilation of 4 invited and 34 contributed papers presented in six sessions: algorithms one and two, turbomachinery, turbulence, components application, and combustors. Topics include numerical methods, grid generation, chemically reacting flows, turbulence modeling, inlets, nozzles, and unsteady flows.

A transient thermal model of a neutral buoyancy cryogenic fluid delivery system

NASA Astrophysics Data System (ADS)

Bue, Grant C.; Conger, Bruce S.

A thermal-performance model is presently used to evaluate a preliminary Neutral Buoyancy Cryogenic fluid-delivery system for underwater EVA training. Attention is given to the modeling of positional transients generated from the moving of internal components, including the control of cycling artifacts, as well as to the convection and boiling characteristics of the cryofluid, 250-psi N2/O2 gas, and water contained in the tank. Two piston designs are considered according to performance criteria; temperature and heat-transfer rate profiles are presented.

Public health systems research: the state of the field.

PubMed

Bagley, Prue; Lin, Vivian

2008-11-01

Public health infrastructure provides the building blocks required for the system to achieve public health goals. A systems approach to public health has been suggested as a means to tackle persistent and emerging problems. Systems and infrastructure are attracting increased research attention. A review of the Australian and international literature suggests an absence of empirical evidence about how the system and its component parts does, or should, work and highlights some of the difficulties associated with generating such evidence. It also indicates there is significant scope for further research.

Numerical study on static component generation from the primary Lamb waves propagating in a plate with nonlinearity

NASA Astrophysics Data System (ADS)

Wan, Xiang; Tse, Peter W.; Zhang, Xuhui; Xu, Guanghua; Zhang, Qing; Fan, Hongwei; Mao, Qinghua; Dong, Ming; Wang, Chuanwei; Ma, Hongwei

2018-04-01

Under the discipline of nonlinear ultrasonics, in addition to second harmonic generation, static component generation is another frequently used nonlinear ultrasonic behavior in non-destructive testing (NDT) and structural health monitoring (SHM) communities. However, most previous studies on static component generation are mainly based on using longitudinal waves. It is desirable to extend static component generation from primary longitudinal waves to primary Lamb waves. In this paper, static component generation from the primary Lamb waves is studied. Two major issues are numerically investigated. First, the mode of static displacement component generated from different primary Lamb wave modes is identified. Second, cumulative effect of static displacement component from different primary Lamb wave modes is also discussed. Our study results show that the static component wave packets generated from the primary S0, A0 and S1 modes share the almost same group velocity equal to the phase velocity of S0 mode tending to zero frequency c plate . The finding indicates that whether the primary mode is S0, A0 or S1, the static components generated from these primary modes always share the nature of S0 mode. This conclusion is also verified by the displacement filed of these static components that the horizontal displacement field is almost uniform and the vertical displacement filed is antisymmetric across the thickness of the plate. The uniform distribution of horizontal displacement filed enables the static component, regardless of the primary Lamb modes, to be a promising technique for evaluating microstructural damages buried in the interior of a structure. Our study also illustrates that the static components are cumulative regardless of whether the phase velocity of the primary and secondary waves is matched or not. This observation indicates that the static component overcomes the limitations of the traditional nonlinear Lamb waves satisfying phase velocity matching condition to achieve cumulative second harmonic generation. This nature also enables the primary Lamb waves excited at a low center frequency to generate static component used for inspecting large-scale structures with micro-scale damages.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kirk, Bernadette Lugue; Eipeldauer, Mary D; Whitaker, J Michael

In 2007, the Department of Energy's National Nuclear Security Administration (DOE/NNSA) Office of Nonproliferation and International Security (NA-24) completed a comprehensive review of the current and potential future challenges facing the international safeguards system. The review examined trends and events impacting the mission of international safeguards and the implications of expanding and evolving mission requirements on the legal authorities and institutions that serve as the foundation of the international safeguards system, as well as the technological, financial, and human resources required for effective safeguards implementation. The review's findings and recommendations were summarized in the report, 'International Safeguards: Challenges and Opportunitiesmore » for the 21st Century (October 2007)'. One of the report's key recommendations was for DOE/NNSA to launch a major new program to revitalize the international safeguards technology and human resource base. In 2007, at the International Atomic Energy Agency's General Conference, then Secretary of Energy Samuel W. Bodman announced the newly created Next Generation Safeguards Initiative (NGSI). NGSI consists of five program elements: (1) Policy development and outreach; (2) Concepts and approaches; (3) Technology and analytical methodologies; (4) Human resource development; and (5) Infrastructure development. The ensuing report addresses the 'Human Resource Development (HRD)' component of NGSI. The goal of the HRD as defined in the NNSA Program Plan (November 2008) is 'to revitalize and expand the international safeguards human capital base by attracting and training a new generation of talent.' One of the major objectives listed in the HRD goal includes education and training, outreach to universities, professional societies, postdoctoral appointments, and summer internships at national laboratories. ORNL is a participant in the NGSI program, together with several DOE laboratories such as Pacific Northwest National Laboratory (PNNL), Lawrence Livermore National Laboratory (LLNL), Brookhaven National Laboratory (BNL), and Los Alamos National Laboratory (LANL). In particular, ORNL's participation encompasses student internships, postdoctoral appointments, collaboration with universities in safeguards curriculum development, workshops, and outreach to professional societies through career fairs.« less

The PartnerWeb Project: a component-based approach to enterprise-wide information integration and dissemination.

PubMed Central

Karson, T. H.; Perkins, C.; Dixon, C.; Ehresman, J. P.; Mammone, G. L.; Sato, L.; Schaffer, J. L.; Greenes, R. A.

1997-01-01

A component-based health information resource, delivered on an intranet and the Internet, utilizing World Wide Web (WWW) technology, has been built to meet the needs of a large integrated delivery network (IDN). Called PartnerWeb, this resource is intended to provide a variety of health care and reference information to both practitioners and consumers/patients. The initial target audience has been providers. Content management for the numerous departments, divisions, and other organizational entities within the IDN is accomplished by a distributed authoring and editing environment. Structured entry using a set of form tools into databases facilitates consistency of information presentation, while empowering designated authors and editors in the various entities to be responsible for their own materials, but not requiring them to be technically skilled. Each form tool manages an encapsulated component. The output of each component can be a dynamically generated display on WWW platforms, or an appropriate interface to other presentation environments. The PartnerWeb project lays the foundation for both an internal and external communication infrastructure for the enterprise that can facilitate information dissemination. PMID:9357648

Path Analysis of Acculturative Stress Components and Their Relationship with Depression Among International Students in China.

PubMed

Liu, Yang; Chen, Xinguang; Li, Shiyue; Yu, Bin; Wang, Yan; Yan, Hong

2016-12-01

Acculturative stress prevents international students from adapting to the host culture, increasing their risk for depression. International students in China are a growing and at-risk population for acculturative stress and depression. With data from the International Student Health and Behaviour Survey (Yu et al., ) in China, seven acculturative stress components were detected in a previous study (Yu et al., ), including a central component (self-confidence), three distal components (value conflict, identity threat and rejection) and three proximal components (poor cultural competence, opportunity deprivation and homesickness). The current study extended the previous study to investigate the relationship between these components and depression with data also from International Student Health and Behaviour Survey. Participants were 567 students (59% male, 40.4% African, mean age = 22.75, SD = 4.11) recruited in Wuhan, China. The sample scored high on the Acculturative Stress Scale for International Students (M = 92.81, SD = 23.93) and Center for Epidemiologic Studies Short Depression Scale (M = 0.97, SD = 0.53). Acculturative stress was positively associated with depression; the association between the three distal stress components and depression was fully mediated through self-confidence, while the three proximal components had a direct effect and a self-confidence-mediated indirect effect. These findings extended the value of the previous study, highlighted the central role of self-confidence in understanding acculturative stress and depression and provided new data supporting more effective counselling for international students in China. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

Reactor plasma facing component designs based on liquid metal concepts supported in porous systems

NASA Astrophysics Data System (ADS)

Tabarés, F. L.; Oyarzabal, E.; Martin-Rojo, A. B.; Tafalla, D.; de Castro, A.; Soleto, A.

2017-01-01

The use of liquid metals (LMs) as plasma facing components in fusion devices was proposed as early as 1970 for a field reversed concept and inertial fusion reactors. The idea was extensively developed during the APEX Project, at the turn of the century, and it is the subject at present of the biennial International Symposium on Lithium Applications (ISLA), whose fourth meeting took place in Granada, Spain at the end of September 2015. While liquid metal flowing concepts were specially addressed in USA research projects, the idea of embedding the metal in a capillary porous system (CPS) was put forwards by Russian teams in the 1990s, thus opening the possibility of static concepts. Since then, many ideas and accompanying experimental tests in fusion devices and laboratories have been produced, involving a large fraction of countries within the international fusion community. Within the EUROFusion Roadmap, these activities are encompassed into the working programs of the plasma facing components (PFC) and divertor tokamak test (DTT) packages. In this paper, a review of the state of the art in concepts based on the CPS set-up for a fusion reactor divertor target, aimed at preventing the ejection of the liquid metal by electro-magnetic (EM) forces generated under plasma operation, is described and required R+D activities on the topic, including ongoing work at CIEMAT specifically oriented to filling the remaining gaps, are stressed.

78 FR 2281 - Certain Robotic Toys and Components Thereof; Notice of Receipt of Complaint; Solicitation of...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-10

... INTERNATIONAL TRADE COMMISSION [Docket No. 2930] Certain Robotic Toys and Components Thereof.... International Trade Commission. ACTION: Notice. SUMMARY: Notice is hereby given that the U.S. International.... International Trade Commission, 500 E Street SW., Washington, DC 20436, telephone (202) 205-2000. The public...

Applications of Neutron Radiography for the Nuclear Power Industry

NASA Astrophysics Data System (ADS)

Craft, Aaron E.; Barton, John P.

The World Conference on Neutron Radiography (WCNR) and International Topical Meeting on Neutron Radiography (ITMNR) series have been running over 35 years. The most recent event, ITMNR-8, focused on industrial applications and was the first time this series was hosted in China. In China, more than twenty new nuclear power plants are under construction and plans have been announced to increase the nuclear capacity by a factor of three within fifteen years. There are additional prospects in many other nations. Neutron tests were vital during previous developments of materials and components for nuclear power applications, as reported in the WCNR and ITMNR conference series. For example a majority of the 140 papers in the Proceedings of the First WCNR are for the benefit of the nuclear power industry. Many of those techniques are being utilized and advanced to the present time. Neutron radiography of irradiated nuclear fuel provides more comprehensive information about the internal condition of irradiated nuclear fuel than any other non-destructive technique to date. Applications include examination of nuclear waste, nuclear fuels, cladding, control elements, and other critical components. In this paper, applications of neutron radiography techniques developed and applied internationally for the nuclear power industry since the earliest years are reviewed, and the question is asked whether neutron test techniques, in general, can be of value in development of the present and future generations of nuclear power plants world-wide.

Predicting the velocity and azimuth of fragments generated by the range destruction or random failure of rocket casings and tankage

NASA Technical Reports Server (NTRS)

Eck, Marshall; Mukunda, Meera

1988-01-01

A calculational method is described which provides a powerful tool for predicting solid rocket motor (SRM) casing and liquid rocket tankage fragmentation response. The approach properly partitions the available impulse to each major system-mass component. It uses the Pisces code developed by Physics International to couple the forces generated by an Eulerian-modeled gas flow field to a Lagrangian-modeled fuel and casing system. The details of the predictive analytical modeling process and the development of normalized relations for momentum partition as a function of SRM burn time and initial geometry are discussed. Methods for applying similar modeling techniques to liquid-tankage-overpressure failures are also discussed. Good agreement between predictions and observations are obtained for five specific events.

Components of a Measure to Describe Organizational Culture in Academic Pharmacy.

PubMed

Desselle, Shane; Rosenthal, Meagen; Holmes, Erin R; Andrews, Brienna; Lui, Julia; Raja, Leela

2017-12-01

Objective. To develop a measure of organizational culture in academic pharmacy and identify characteristics of an academic pharmacy program that would be impactful for internal (eg, students, employees) and external (eg, preceptors, practitioners) clients of the program. Methods. A three-round Delphi procedure of 24 panelists from pharmacy schools in the U.S. and Canada generated items based on the Organizational Culture Profile (OCP), which were then evaluated and refined for inclusion in subsequent rounds. Items were assessed for appropriateness and impact. Results. The panel produced 35 items across six domains that measured organizational culture in academic pharmacy: competitiveness, performance orientation, social responsibility, innovation, emphasis on collegial support, and stability. Conclusion. The items generated require testing for validation and reliability in a large sample to finalize this measure of organizational culture.

MO-F-CAMPUS-J-03: Sorting 2D Dynamic MR Images Using Internal Respiratory Signal for 4D MRI

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wen, Z; Hui, C; Beddar, S

Purpose: To develop a novel algorithm to extract internal respiratory signal (IRS) for sorting dynamic magnetic resonance (MR) images in order to achieve four-dimensional (4D) MR imaging. Methods: Dynamic MR images were obtained with the balanced steady state free precession by acquiring each two-dimensional sagittal slice repeatedly for more than one breathing cycle. To generate a robust IRS, we used 5 different representative internal respiratory surrogates in both the image space (body area) and the Fourier space (the first two low-frequency phase components in the anterior-posterior direction, and the first two low-frequency phase components in the superior-inferior direction). A clusteringmore » algorithm was then used to search for a group of similar individual internal signals, which was then used to formulate the final IRS. A phantom study and a volunteer study were performed to demonstrate the effectiveness of this algorithm. The IRS was compared to the signal from the respiratory bellows. Results: The IRS computed by our algorithm matched well with the bellows signal in both the phantom and the volunteer studies. On average, the normalized cross correlation between the IRS and the bellows signal was 0.97 in the phantom study and 0.87 in the volunteer study, respectively. The average difference between the end inspiration times in the IRS and bellows signal was 0.18 s in the phantom study and 0.14 s in the volunteer study, respectively. 4D images sorted based on the IRS showed minimal mismatched artifacts, and the motion of the anatomy was coherent with the respiratory phases. Conclusion: A novel algorithm was developed to generate IRS from dynamic MR images to achieve 4D MR imaging. The performance of the IRS was comparable to that of the bellows signal. It can be easily implemented into the clinic and potentially could replace the use of external respiratory surrogates. This research was partially funded by the the Center for Radiation Oncology Research from UT MD Anderson Cancer Center.« less

The N2-P3 complex of the evoked potential and human performance

NASA Technical Reports Server (NTRS)

Odonnell, Brian F.; Cohen, Ronald A.

1988-01-01

The N2-P3 complex and other endogenous components of human evoked potential provide a set of tools for the investigation of human perceptual and cognitive processes. These multidimensional measures of central nervous system bioelectrical activity respond to a variety of environmental and internal factors which have been experimentally characterized. Their application to the analysis of human performance in naturalistic task environments is just beginning. Converging evidence suggests that the N2-P3 complex reflects processes of stimulus evaluation, perceptual resource allocation, and decision making that proceed in parallel, rather than in series, with response generation. Utilization of these EP components may provide insights into the central nervous system mechanisms modulating task performance unavailable from behavioral measures alone. The sensitivity of the N2-P3 complex to neuropathology, psychopathology, and pharmacological manipulation suggests that these components might provide sensitive markers for the effects of environmental stressors on the human central nervous system.

Tailoring International Pressure Ulcer Prevention Guidelines for Nigeria: A Knowledge Translation Study Protocol.

PubMed

Ilesanmi, Rose Ekama; Gillespie, Brigid M; Adejumo, Prisca Olabisi; Chaboyer, Wendy

2015-07-28

The 2014 International Pressure Ulcer Prevention (PUP) Clinical Practice Guidelines (CPG) provides the most current evidence based strategies to prevent Pressure Ulcer (PU). The evidence upon which these guidelines have been developed has predominantly been generated from research conducted in developed countries. Some of these guidelines may not be feasible in developing countries due to structural and resource issues; therefore there is a need to adapt these guidelines to the context thus making it culturally acceptable. To present a protocol detailing the tailoring of international PUPCPG into a care bundle for the Nigerian context. Guided by the Knowledge to Action (KTA) framework, a two phased study will be undertaken. In Phase 1, the Delphi technique with stakeholder leaders will be used to review the current PUPCPG, identifying core strategies that are feasible to be adopted in Nigeria. These core strategies will become components of a PUP care bundle. In Phase 2, key stakeholder interviews will be used to identify the barriers, facilitators and potential implementation strategies to promote uptake of the PUP care bundle. A PUP care bundle, with three to eight components is expected to be developed from Phase 1. Implementation strategies to promote adoption of the PUP care bundle into clinical practice in selected Nigerian hospitals, is expected to result from Phase 2. Engagement of key stakeholders and consumers in the project should promote successful implementation and translate into better patient care. Using KTA, a knowledge translation framework, to guide the implementation of PUPCPG will enhance the likelihood of successful adoption in clinical practice. In implementing a PUP care bundle, developing countries face a number of challenges such as the feasibility of its components and the required resources.

Summary Report of Summer 2009 NGSI Human Capital Development Efforts at Lawrence Livermore National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dougan, A; Dreicer, M; Essner, J

2009-11-16

In 2009, Lawrence Livermore National Laboratory (LLNL) engaged in several activities to support NA-24's Next Generation Safeguards Initiative (NGSI). This report outlines LLNL's efforts to support Human Capital Development (HCD), one of five key components of NGSI managed by Dunbar Lockwood in the Office of International Regimes and Agreements (NA-243). There were five main LLNL summer safeguards HCD efforts sponsored by NGSI: (1) A joint Monterey Institute of International Studies/Center for Nonproliferation Studies-LLNL International Safeguards Policy and Information Analysis Course; (2) A Summer Safeguards Policy Internship Program at LLNL; (3) A Training in Environmental Sample Analysis for IAEA Safeguards Internship;more » (4) Safeguards Technology Internships; and (5) A joint LLNL-INL Summer Safeguards Lecture Series. In this report, we provide an overview of these five initiatives, an analysis of lessons learned, an update on the NGSI FY09 post-doc, and an update on students who participated in previous NGSI-sponsored LLNL safeguards HCD efforts.« less

Performance of Water Recirculation Loop Maintenance Components for the Advanced Spacesuit Water Membrane Evaporator

NASA Technical Reports Server (NTRS)

Rector, Tony; Peyton, Barbara M.; Steele, John W.; Makinen, Janice; Bue, Grant C.; Campbell, Colin

2014-01-01

Water loop maintenance components to maintain the water quality of the Advanced Spacesuit Water Membrane Evaporation (SWME) water recirculation loop have undergone a comparative performance evaluation with a second SWME water recirculation loop with no water quality maintenance. Results show the benefits of periodic water maintenance. The SWME is a heat rejection device under development at the NASA Johnson Space Center to perform thermal control for advanced spacesuits. One advantage to this technology is the potential for a significantly greater degree of tolerance to contamination when compared to the existing Sublimator technology. The driver for the evaluation of water recirculation maintenance components was to further enhance this advantage through the leveraging of fluid loop management lessons learned from the International Space Station (ISS). A bed design that was developed for a UTAS military application, and considered for a potential ISS application with the Urine Processor Assembly, provided a low pressure drop means for water maintenance in a recirculation loop. The bed design is coupled with high capacity ion exchange resins, organic adsorbents, and a cyclic methodology developed for the Extravehicular Mobility Unit (EMU) Transport Water loop. The maintenance cycle included the use of a biocide delivery component developed for ISS to introduce a biocide in a microgravity compatible manner for the Internal Active Thermal Control System (IATCS). The leveraging of these water maintenance technologies to the SWME recirculation loop is a unique demonstration of applying the valuable lessons learned on the ISS to the next generation of manned spaceflight Environmental Control and Life Support System (ECLSS) hardware.

Performance of Water Recirculation Loop Maintenance Components for the Advanced Spacesuit Water Membrane Evaporator

NASA Technical Reports Server (NTRS)

Rector, Tony; Peyton, Barbara M.; Steele, John W.; Makinen, Janice; Bue, Grant C.; Campbell, Colin

2014-01-01

Water loop maintenance components to maintain the water quality of the Advanced Spacesuit Water Membrane Evaporation (SWME) water recirculation loop have undergone a comparative performance evaluation with a recirculating control loop which had no water quality maintenance. Results show that periodic water maintenance can improve performance of the SWME. The SWME is a heat rejection device under development at the NASA Johnson Space Center to perform thermal control for advanced spacesuits. One advantage of this technology is the potential for a significantly greater degree of tolerance to contamination when compared to the existing sublimator technology. The driver for the evaluation of water recirculation maintenance components was to enhance the robustness of the SWME through the leveraging of fluid loop management lessons learned from the International Space Station (ISS). A patented bed design that was developed for a United Technologies Aerospace System military application provided a low pressure drop means for water maintenance in the SWME recirculation loop. The bed design is coupled with high capacity ion exchange resins, organic adsorbents, and a cyclic methodology developed for the Extravehicular Mobility Unit (EMU) Transport Water loop. The maintenance cycle included the use of a biocide delivery component developed for the ISS to introduce a biocide in a microgravity compatible manner for the Internal Active Thermal Control System (IATCS). The leveraging of these water maintenance technologies to the SWME recirculation loop is a unique demonstration of applying the valuable lessons learned on the ISS to the next generation of manned spaceflight Environmental Control and Life Support System (ECLSS) hardware.

Performance of Water Recirculation Loop Maintentance Components for the Advanced Spacesuit Water Membrane Evaporator

NASA Technical Reports Server (NTRS)

Rector, Tony; Peyton, Barbara; Steele, John W.; Bue, Grant C.; Campbell, Colin; Makinen, Janice

2014-01-01

Water loop maintenance components to maintain the water quality of the Advanced Spacesuit Water Membrane Evaporation (SWME) water recirculation loop have undergone a comparative performance evaluation with a second SWME water recirculation loop with no water quality maintenance. Results show the benefits of periodic water maintenance. The SWME is a heat rejection device under development at the NASA Johnson Space Center to perform thermal control for advanced spacesuits. One advantage to this technology is the potential for a significantly greater degree of tolerance to contamination when compared to the existing Sublimator technology. The driver for the evaluation of water recirculation maintenance components was to further enhance this advantage through the leveraging of fluid loop management lessonslearned from the International Space Station (ISS). A bed design that was developed for a UTAS military application, and considered for a potential ISS application with the Urine Processor Assembly, provided a low pressure drop means for water maintenance in a recirculation loop. The bed design is coupled with high capacity ion exchange resins, organic adsorbents, and a cyclic methodology developed for the Extravehicular Mobility Unit (EMU) Transport Water loop. The maintenance cycle included the use of a biocide delivery component developed for ISS to introduce a biocide in a microgravity-compatible manner for the Internal Active Thermal Control System (IATCS). The leveraging of these water maintenance technologies to the SWME recirculation loop is a unique demonstration of applying the valuable lessons learned on the ISS to the next generation of manned spaceflight Environmental Control and Life Support System (ECLSS) hardware.

Psychometric properties of the International Classification of Functioning, Disability and Health set for spinal cord injury nursing based on Rasch analysis.

PubMed

Li, Kun; Yan, Tiebin; You, Liming; Xie, Sumei; Li, Yun; Tang, Jie; Wang, Yingmin; Gao, Yan

2018-02-01

To examine the psychometric properties of the International Classification of Functioning, Disability and Health (ICF) set for spinal cord injury nursing (ICF-SCIN) using Rasch analysis. A total of 140 spinal cord injury patients were recruited between December 2013 and March 2014 through convenience sampling. Nurses used the components body functions (BF), body structures (BS), and activities and participation (AP) of the ICF-SCIN to rate the patients' functioning. Rasch analysis was performed using RUMM 2030 software. In each component, categories were rescored from 01234 to 01112 because of reversed thresholds. Nine testlets were created to overcome local dependency. Four categories which fit to the Rasch model poorly were deleted. After modification, the components BF, BS, and AP showed good fit to the Rasch model with a Bonferroni-adjusted significant level (χ 2  =   86.29, p = 0.006; χ 2  =   22.44, p = 0.130; χ 2  =   39.92, p = 0.159). The person separation indices (PSIs) for the three components were 0.80, 0.54, and 0.97, respectively. No differential item functioning (DIF) was detected across age, gender, or educational level. The fit properties of the ICF set were satisfactory after modifications. The ICF-SCIN has the potential as a nursing assessment instrument for measuring the functioning of patients with spinal cord injury. Implications for rehabilitation The International Classification of Functioning, Disability and Health (ICF) set for spinal cord injury nursing contains a group of categories which can reflect the functioning of spinal cord injury patients from the perspective of nurses. The components body functions (BF), body structures (BS), and activities and participation (AP) of the ICF set for spinal cord injury achieved the fit to the Rasch model through rescoring, generating testlets, and deleting categories with poor fit. The ICF set for spinal cord injury nursing (ICF-SCIN) has the potential to be used as a clinical nursing assessment tool in measuring the functioning of patients with spinal cord injury.

On the characterization of ultra-precise X-ray optical components: advances and challenges in ex situ metrology

PubMed Central

Siewert, F.; Buchheim, J.; Zeschke, T.; Störmer, M.; Falkenberg, G.; Sankari, R.

2014-01-01

To fully exploit the ultimate source properties of the next-generation light sources, such as free-electron lasers (FELs) and diffraction-limited storage rings (DLSRs), the quality requirements for gratings and reflective synchrotron optics, especially mirrors, have significantly increased. These coherence-preserving optical components for high-brightness sources will feature nanoscopic shape accuracies over macroscopic length scales up to 1000 mm. To enable high efficiency in terms of photon flux, such optics will be coated with application-tailored single or multilayer coatings. Advanced thin-film fabrication of today enables the synthesis of layers on the sub-nanometre precision level over a deposition length of up to 1500 mm. Specifically dedicated metrology instrumentation of comparable accuracy has been developed to characterize such optical elements. Second-generation slope-measuring profilers like the nanometre optical component measuring machine (NOM) at the BESSY-II Optics laboratory allow the inspection of up to 1500 mm-long reflective optical components with an accuracy better than 50 nrad r.m.s. Besides measuring the shape on top of the coated mirror, it is of particular interest to characterize the internal material properties of the mirror coating, which is the domain of X-rays. Layer thickness, density and interface roughness of single and multilayer coatings are investigated by means of X-ray reflectometry. In this publication recent achievements in the field of slope measuring metrology are shown and the characterization of different types of mirror coating demonstrated. Furthermore, upcoming challenges to the inspection of ultra-precise optical components designed to be used in future FEL and DLSR beamlines are discussed. PMID:25177985

Effects of Internal Waves on Sound Propagation in the Shallow Waters of the Continental Shelves

DTIC Science & Technology

2016-09-01

experiment area were largely generated by tidal forcing. Compared to simulations without internal waves , simulations accounting for the effects of...internal waves in the experiment area were largely generated by tidal forcing. Compared to simulations without internal waves , simulations accounting for...IN THE SHALLOW WATERS OF THE CONTINENTAL SHELVES ..................................4  1.  Internal Tides—Internal Waves Generated by Tidal Forcing

Calculation of periodic flows in a continuously stratified fluid

NASA Astrophysics Data System (ADS)

Vasiliev, A.

2012-04-01

Analytic theory of disturbances generated by an oscillating compact source in a viscous continuously stratified fluid was constructed. Exact solution of the internal waves generation problem was constructed taking into account diffusivity effects. This analysis is based on set of fundamental equations of incompressible flows. The linearized problem of periodic flows in a continuously stratified fluid, generated by an oscillating part of the inclined plane was solved by methods of singular perturbation theory. A rectangular or disc placed on a sloping plane and oscillating linearly in an arbitrary direction was selected as a source of disturbances. The solutions include regularly perturbed on dissipative component functions describing internal waves and a family of singularly perturbed functions. One of the functions from the singular components family has an analogue in a homogeneous fluid that is a periodic or Stokes' flow. Its thickness is defined by a universal micro scale depending on kinematics viscosity coefficient and a buoyancy frequency with a factor depending on the wave slope. Other singular perturbed functions are specific for stratified flows. Their thickness are defined the diffusion coefficient, kinematic viscosity and additional factor depending on geometry of the problem. Fields of fluid density, velocity, vorticity, pressure, energy density and flux as well as forces acting on the source are calculated for different types of the sources. It is shown that most effective source of waves is the bi-piston. Complete 3D problem is transformed in various limiting cases that are into 2D problem for source in stratified or homogeneous fluid and the Stokes problem for an oscillating infinite plane. The case of the "critical" angle that is equality of the emitting surface and the wave cone slope angles needs in separate investigations. In this case, the number of singular component is saved. Patterns of velocity and density fields were constructed and analyzed by methods of computational mathematics. Singular components of the solution affect the flow pattern of the inhomogeneous stratified fluid, not only near the source of the waves, but at a large distance. Analytical calculations of the structure of wave beams are matched with laboratory experiments. Some deviations at large distances from the source are formed due to the contribution of background wave field associated with seiches in the laboratory tank. In number of the experiments vortices with closed contours were observed on some distances from the disk. The work was supported by Ministry of Education and Science RF (Goscontract No. 16.518.11.7059), experiments were performed on set up USU "HPC IPMec RAS".

Relational and item-specific influences on generate-recognize processes in recall.

PubMed

Guynn, Melissa J; McDaniel, Mark A; Strosser, Garrett L; Ramirez, Juan M; Castleberry, Erica H; Arnett, Kristen H

2014-02-01

The generate-recognize model and the relational-item-specific distinction are two approaches to explaining recall. In this study, we consider the two approaches in concert. Following Jacoby and Hollingshead (Journal of Memory and Language 29:433-454, 1990), we implemented a production task and a recognition task following production (1) to evaluate whether generation and recognition components were evident in cued recall and (2) to gauge the effects of relational and item-specific processing on these components. An encoding task designed to augment item-specific processing (anagram-transposition) produced a benefit on the recognition component (Experiments 1-3) but no significant benefit on the generation component (Experiments 1-3), in the context of a significant benefit to cued recall. By contrast, an encoding task designed to augment relational processing (category-sorting) did produce a benefit on the generation component (Experiment 3). These results converge on the idea that in recall, item-specific processing impacts a recognition component, whereas relational processing impacts a generation component.

A technical review of cellular radio and analysis of a possible protocol

NASA Astrophysics Data System (ADS)

Reese, William D.

1992-09-01

Radio and television technology made the field of cellular radio possible. This thesis shows the development of radio and television technology from both a historical and technical aspect. A review of the important researchers and their contributions is followed by a technical explanation of the theories behind electromagnetic radiation of radio and television signals and the technology which was developed to implement such transmissions. The evolution of development which the paper outlines begins with some of the first theories about electricity and magnetism and the subsequent mathematical foundation developed to explain them. This is followed by a number of experimental and developmental researchers and their contributions. The bulk of the paper is concentrated on explaining the earliest generations of radio and all generations of television. The major components of both radio and television are described in detail along with an explanation of what they do and how they work. Such components, in many cases, found important uses in fields outside those for which they were developed. A brief overview of the regulatory environment of each technology and the U.S. and international standardization efforts is also included. Finally, the paper illustrates a modern-day application of radio technology--the cellular radio industry. A description of the components and their functions is followed by a possible cellular radio protocol and analysis.

Neutron Characterization for Additive Manufacturing

NASA Technical Reports Server (NTRS)

Watkins, Thomas; Bilheux, Hassina; An, Ke; Payzant, Andrew; DeHoff, Ryan; Duty, Chad; Peter, William; Blue, Craig; Brice, Craig A.

2013-01-01

Oak Ridge National Laboratory (ORNL) is leveraging decades of experience in neutron characterization of advanced materials together with resources such as the Spallation Neutron Source (SNS) and the High Flux Isotope Reactor (HFIR) shown in Fig. 1 to solve challenging problems in additive manufacturing (AM). Additive manufacturing, or three-dimensional (3-D) printing, is a rapidly maturing technology wherein components are built by selectively adding feedstock material at locations specified by a computer model. The majority of these technologies use thermally driven phase change mechanisms to convert the feedstock into functioning material. As the molten material cools and solidifies, the component is subjected to significant thermal gradients, generating significant internal stresses throughout the part (Fig. 2). As layers are added, inherent residual stresses cause warping and distortions that lead to geometrical differences between the final part and the original computer generated design. This effect also limits geometries that can be fabricated using AM, such as thin-walled, high-aspect- ratio, and overhanging structures. Distortion may be minimized by intelligent toolpath planning or strategic placement of support structures, but these approaches are not well understood and often "Edisonian" in nature. Residual stresses can also impact component performance during operation. For example, in a thermally cycled environment such as a high-pressure turbine engine, residual stresses can cause components to distort unpredictably. Different thermal treatments on as-fabricated AM components have been used to minimize residual stress, but components still retain a nonhomogeneous stress state and/or demonstrate a relaxation-derived geometric distortion. Industry, federal laboratory, and university collaboration is needed to address these challenges and enable the U.S. to compete in the global market. Work is currently being conducted on AM technologies at the ORNL Manufacturing Demonstration Facility (MDF) sponsored by the DOE's Advanced Manufacturing Office. The MDF is focusing on R&D of both metal and polymer AM pertaining to in-situ process monitoring and closed-loop controls; implementation of advanced materials in AM technologies; and demonstration, characterization, and optimization of next-generation technologies. ORNL is working directly with industry partners to leverage world-leading facilities in fields such as high performance computing, advanced materials characterization, and neutron sciences to solve fundamental challenges in advanced manufacturing. Specifically, MDF is leveraging two of the world's most advanced neutron facilities, the HFIR and SNS, to characterize additive manufactured components.

Crash Models for Advanced Automotive Batteries: A Review of the Current State of the Art

DOE Office of Scientific and Technical Information (OSTI.GOV)

Turner, John A.; Allu, Srikanth; Gorti, Sarma B.

Safety is a critical aspect of lithium-ion (Li-ion) battery design. Impact/crash conditions can trigger a complex interplay of mechanical contact, heat generation and electrical discharge, which can result in adverse thermal events. The cause of these thermal events has been linked to internal contact between the opposite electrodes, i.e. internal short circuit. The severity of the outcome is influenced by the configuration of the internal short circuit and the battery state. Different loading conditions and battery states may lead to micro (soft) shorts where material burnout due to generated heat eliminates contact between the electrodes, or persistent (hard) shorts whichmore » can lead to more significant thermal events and potentially damage the entire battery system and beyond. Experimental characterization of individual battery components for the onset of internal shorts is limited, since it is impractical to canvas all possible variations in battery state of charge, operating conditions, and impact loading in a timely manner. This report provides a survey of modeling and simulation approaches and documents a project initiated and funded by DOT/NHTSA to improve modeling and simulation capabilities in order to design tests that provide leading indicators of failure in batteries. In this project, ORNL has demonstrated a computational infrastructure to conduct impact simulations of Li-ion batteries using models that resolve internal structures and electro-thermo-chemical and mechanical conditions. Initial comparisons to abuse experiments on cells and cell strings conducted at ORNL and Naval Surface Warfare Center (NSWC) at Carderock MD for parameter estimation and model validation have been performed. This research has provided insight into the mechanisms of deformation in batteries (both at cell and electrode level) and their relationship to the safety of batteries.« less

International Laser Ranging Service (ILRS) 1999 Annual Report

NASA Technical Reports Server (NTRS)

Pearlman, Michael (Editor); Taggert, Linda (Editor)

2000-01-01

This 1999 Annual Report of the International Laser Ranging Service (ILRS) is comprised of individual contributions from ILRS components within the international geodetic community. This report documents the work of the ILRS components from the inception of the Service through December 31,1999. Since the service has only recently been established, the ILRS associates decided to publish this Annual report as a reference to our organization and its components.

Cabin Air Quality On Board Mir and the International Space Station: A Comparison

NASA Technical Reports Server (NTRS)

Macatangay, Ariel; Perry, Jay L.

2007-01-01

The maintenance of the cabin atmosphere aboard spacecraft is critical not only to its habitability but also to its function. Ideally, air quality can be maintained by striking a proper balance between the generation and removal of contaminants. Both very dynamic processes, the balance between generation and removal can be difficult to maintain and control because the state of the cabin atmosphere is in constant evolution responding to different perturbations. Typically, maintaining a clean cabin environment on board crewed spacecraft and space habitats is the central function of the environmental control and life support (ECLS) system. While active air quality control equipment is deployed on board every vehicle to remove carbon dioxide, water vapor, and trace chemical components from the cabin atmosphere, perturbations associated with logistics, vehicle construction and maintenance, and ECLS system configuration influence the resulting cabin atmospheric quality. The air-quality data obtained from the International Space Station (ISS) and NASA-Mir programs provides a wealth of information regarding the maintenance of the cabin atmosphere aboard long-lived space habitats. A comparison of the composition of the trace chemical contaminant load is presented. Correlations between ground-based and in-flight operations that influence cabin atmospheric quality are identified and discussed, and observations on cabin atmospheric quality during the NASA-Mir expeditions and the International Space Station are explored.

Generation of nano-voids inside polylactide using femtosecond laser radiation

NASA Astrophysics Data System (ADS)

Viertel, Tina; Pabst, Linda; Olbrich, Markus; Ebert, Robby; Horn, Alexander; Exner, Horst

2017-12-01

The arrangement of nanometer-sized voids, induced by focusing intense laser radiation within transparent material can allow the generation of transparent components with dimensions in the micrometer to nanometre range due to internal contour cut and thus satisfy the progressive miniaturization of products in micro-optics and medical technologies. For further improvements in the precision of those components, a deep understanding of the involved processes during the interaction of laser radiation within the material is necessary. In this work, voids inside bulk polylactide (PLA), a bioabsorbable polymer, were generated using a femtosecond laser ( λ = 1030 nm, τH = 180 fs) with single and multiple pulse irradiation. The dependence of the spot size was examined by the use of four microscope objectives with focus radii of 4.9, 3.3, 2 and 1.2 µm. For the experiments, the pulse energy and focusing depth into the material were varied. The dimensions of the voids were experimentally determined as function of the intensity. Differences in the lateral and axial extents of the voids were obtained for different focus radii and focusing depths at same intensities. Furthermore, the intensity distribution of the laser radiation inside the material for the different focus radii and focusing depths, and their dependence on the lateral and axial sizes of the voids was simulated and compared with the experimental results.

User-driven generation of standard data services

NASA Astrophysics Data System (ADS)

Díaz, Laura; Granell, Carlos; Gould, Michael; Huerta, Joaquín.

2010-05-01

Geospatial Information systems are experiencing the shift from monolithic to distributed environments (Bernard, 2003). Current research trends for discover and access of geospatial resources, in these distributed environments, are being addressed by deployment of interconnected Spatial Data Infrastructure (SDI) nodes at different scales to build a global spatial information infrastructure (Masser et al., 2008; Rajabifard et al., 2002). One of the challenges for implementing these global and multiscale SDIs is to agree with common standards in consideration with heterogeneity of various stakeholders [Masser 2005]. In Europe, the European Commission took the INSPIRE initiative to monitor the development of European SDIs. INSPIRE Directive addresses the need for web services to discover, view, transform, invoke, and download geospatial resources, which enable various stakeholders to share resources in an interoperable manner [INSPIRE 2007]. Such web services require technical specifications for the interoperability and harmonization of their SDIs [INSPIRE 2007]. Moreover, interoperability is ensured by a number of specification efforts, in the geo domain most prominently by ISO/TC 211 and the OpenGIS Consortium (OGC) (Bernard, 2003). Other research challenges regarding SDI are on one hand how to handle complexity by users in charge of maintaining SDIs as they grow, and on the other hand the fact the SDI maintenance and evolution should be guided (Bejar et al, 2009). So there is a motivation to improve the complex deployment mechanisms in SDI since there is a need of expertise and time to deploy resources and integrate them by means of standard services. In this context we present an architecture following the INSPIRE technical guidelines and therefore based on SDI principles. This architecture supports distributed applications and provides components to assist users in deploying and updating SDI resources. Therefore mechanisms and components for the automatic generation and publication of standard geospatial are proposed. These mechanisms deal with the fact of hiding the underlying technology and let stakeholders wrap resources as standard services to share these resources in a transparent manner. These components are integrated in our architecture within the Service Framework node (module). PIC Figure 1: Figure 1. Architecture components diagram Figure 1 shows the components of the architecture: The Application Node provides the entry point for users to run distributed applications. This software component has the user interface and the application logic. The Service Connector component provides the ability to connect to the services available in the middleware layer of SDI. This node acts as a socket to OGC Web Services. For instance we appreciate the WMS component implementing the OGC WMS specification as it is the standard recommended by the INSPIRE implementation rules as View Service Type.The Service Framework node contains several components. The Service Framework main functionality is to assist users in wrapping and sharing geospatial resources. It implements the proposed mechanisms to improve the availability and visibility of geospatial resources. The main components of this framework are the Data wrapper, the Process Wrapper and the Service Publisher. The Data Wrapper and Process Wrapper components guide users to wrap data and tools as standard services according with INSPIRE implementing rules (availability). The Service Publisher component aims at creating service metadata and publishing them in catalogues (visibility). Roughly speaking, all of these components are concerned with the idea of acting as a service generator and publisher, i.e., they get a resource (data or process) and return an INSPIRE service that will be published in catalogue services. References Béjar, R., Latre, M. Á., Nogueras-Iso, J., Muro-Medrano, P. R., Zarazaga-Soria, F. J. 2009. International Journal of Geographical Information Science, 23(3), 271-294. Bernard, L, U Einspanier, M Lutz & C Portele. Interoperability in GI Service Chains The Way Forward. In: M. Gould, R. Laurini & S. Coulondre (Eds.). 6th AGILE Conference on Geographic Information Science 2003, Lyon: 179-188. INSPIRE. Directive 2007/2/EC of the European Parliament and of the Council of 14 March 2007 establishing an Infrastructure for Spatial Information in the European Community. (2007) Masser, I. GIS Worlds: Creating Spatial Data Infrastructures. Redlands, California. ESRI Press. (2005) Masser, I., Rajabifard, A., Williamson, I. 2008. Spatially enabling governments through SDI implementation. International Journal of Geographical Information Science. Vol. 22, No. 1, (2008) 5-20 Rajabifard, A., Feeney, M-E. F., Williamson, I. P. 2002. Future directions for SDI development. International Journal of Applied Earth Observation and Geoinformation 4 (2002) 11-22

Faculty as Bridges to Co-Curricular Engagement and Community for First-Generation International Students

ERIC Educational Resources Information Center

Glass, Chris R.; Gesing, Peggy; Hales, Angela; Cong, Cong

2017-01-01

The proportion of first-generation international students at US institutions ranges from one-tenth to one-half of the total international student body. First-generation status is an underexplored, and potentially significant, demographic factor in international students' adaptation to college. Researchers used structural equation modelling (SEM)…

Method and apparatus for monitoring aircraft components

DOEpatents

Dickens, Larry M.; Haynes, Howard D.; Ayers, Curtis W.

1996-01-01

Operability of aircraft mechanical components is monitored by analyzing the voltage output of an electrical generator of the aircraft. Alternative generators, for a turbine-driven rotor aircraft, include the gas producer turbine tachometer generator, the power turbine tachometer generator, and the aircraft systems power producing starter/generator. Changes in the peak amplitudes of the fundamental frequency and its harmonics are correlated to changes in condition of the mechanical components.

Method and apparatus for monitoring aircraft components

DOEpatents

Dickens, L.M.; Haynes, H.D.; Ayers, C.W.

1996-01-16

Operability of aircraft mechanical components is monitored by analyzing the voltage output of an electrical generator of the aircraft. Alternative generators, for a turbine-driven rotor aircraft, include the gas producer turbine tachometer generator, the power turbine tachometer generator, and the aircraft systems power producing starter/generator. Changes in the peak amplitudes of the fundamental frequency and its harmonics are correlated to changes in condition of the mechanical components. 14 figs.

Probing the internal structure of the asteriod Didymoon with a passive seismic investigation

NASA Astrophysics Data System (ADS)

Murdoch, N.; Hempel, S.; Pou, L.; Cadu, A.; Garcia, R. F.; Mimoun, D.; Margerin, L.; Karatekin, O.

2017-09-01

Understanding the internal structure of an asteroid has important implications for interpreting its evolutionary history, for understanding its continuing geological evolution, and also for asteroid deflection and in-situ space resource utilisation. Given the strong evidence that asteroids are seismically active, an in-situ passive seismic experiment could provide information about the asteroid surface and interior properties. Here, we discuss the natural seismic activity that may be present on Didymoon, the secondary component of asteroid (65803) Didymos. Our analysis of the tidal stresses in Didymoon shows that tidal quakes are likely to occur if the secondary has an eccentric orbit. Failure occurs most easily at the asteroid poles and close to the surface for both homogeneous and layered internal structures. Simulations of seismic wave propagation in Didymoon show that the seismic moment of even small meteoroid impacts can generate clearly observable body and surface waves if the asteroid's internal structure is homogeneous. The presence of a regolith layer over a consolidated core can result in the seismic energy becoming trapped in the regolith due to the strong impedance contrast at the regolith-core boundary. The inclusion of macro-porosity (voids) further complexifies the wavefield due to increased scattering. The most prominent seismic waves are always found to be those traveling along the surface of the asteroid and those focusing in the antipodal point of the seismic source. We find also that the waveforms and ground acceleration spectra allow discrimination between the different internal structure models. Although the science return of a passive seismic experiment would be enhanced by having multiple seismic stations, one single seismic station can already vastly improve our knowledge about the seismic environment and sub-surface structure of an asteroid. We describe several seismic measurement techniques that could be applied in order to study the asteroid internal structure with one three-component seismic station.

Bias and robustness of uncertainty components estimates in transient climate projections

NASA Astrophysics Data System (ADS)

Hingray, Benoit; Blanchet, Juliette; Jean-Philippe, Vidal

2016-04-01

A critical issue in climate change studies is the estimation of uncertainties in projections along with the contribution of the different uncertainty sources, including scenario uncertainty, the different components of model uncertainty and internal variability. Quantifying the different uncertainty sources faces actually different problems. For instance and for the sake of simplicity, an estimate of model uncertainty is classically obtained from the empirical variance of the climate responses obtained for the different modeling chains. These estimates are however biased. Another difficulty arises from the limited number of members that are classically available for most modeling chains. In this case, the climate response of one given chain and the effect of its internal variability may be actually difficult if not impossible to separate. The estimate of scenario uncertainty, model uncertainty and internal variability components are thus likely to be not really robust. We explore the importance of the bias and the robustness of the estimates for two classical Analysis of Variance (ANOVA) approaches: a Single Time approach (STANOVA), based on the only data available for the considered projection lead time and a time series based approach (QEANOVA), which assumes quasi-ergodicity of climate outputs over the whole available climate simulation period (Hingray and Saïd, 2014). We explore both issues for a simple but classical configuration where uncertainties in projections are composed of two single sources: model uncertainty and internal climate variability. The bias in model uncertainty estimates is explored from theoretical expressions of unbiased estimators developed for both ANOVA approaches. The robustness of uncertainty estimates is explored for multiple synthetic ensembles of time series projections generated with MonteCarlo simulations. For both ANOVA approaches, when the empirical variance of climate responses is used to estimate model uncertainty, the bias is always positive. It can be especially high with STANOVA. In the most critical configurations, when the number of members available for each modeling chain is small (< 3) and when internal variability explains most of total uncertainty variance (75% or more), the overestimation is higher than 100% of the true model uncertainty variance. The bias can be considerably reduced with a time series ANOVA approach, owing to the multiple time steps accounted for. The longer the transient time period used for the analysis, the larger the reduction. When a quasi-ergodic ANOVA approach is applied to decadal data for the whole 1980-2100 period, the bias is reduced by a factor 2.5 to 20 depending on the projection lead time. In all cases, the bias is likely to be not negligible for a large number of climate impact studies resulting in a likely large overestimation of the contribution of model uncertainty to total variance. For both approaches, the robustness of all uncertainty estimates is higher when more members are available, when internal variability is smaller and/or the response-to-uncertainty ratio is higher. QEANOVA estimates are much more robust than STANOVA ones: QEANOVA simulated confidence intervals are roughly 3 to 5 times smaller than STANOVA ones. Excepted for STANOVA when less than 3 members is available, the robustness is rather high for total uncertainty and moderate for internal variability estimates. For model uncertainty or response-to-uncertainty ratio estimates, the robustness is conversely low for QEANOVA to very low for STANOVA. In the most critical configurations (small number of member, large internal variability), large over- or underestimation of uncertainty components is very thus likely. To propose relevant uncertainty analyses and avoid misleading interpretations, estimates of uncertainty components should be therefore bias corrected and ideally come with estimates of their robustness. This work is part of the COMPLEX Project (European Collaborative Project FP7-ENV-2012 number: 308601; http://www.complex.ac.uk/). Hingray, B., Saïd, M., 2014. Partitioning internal variability and model uncertainty components in a multimodel multireplicate ensemble of climate projections. J.Climate. doi:10.1175/JCLI-D-13-00629.1 Hingray, B., Blanchet, J. (revision) Unbiased estimators for uncertainty components in transient climate projections. J. Climate Hingray, B., Blanchet, J., Vidal, J.P. (revision) Robustness of uncertainty components estimates in climate projections. J.Climate

Chance vs. necessity in living systems: a false antinomy.

PubMed

Buiatti, Marcello; Buiatti, Marco

2008-01-01

The concepts of order and randomness are crucial to understand 'living systems' structural and dynamical rules. In the history of biology, they lay behind the everlasting debate on the relative roles of chance and determinism in evolution. Jacques Monod [1970] built a theory where chance (randomness) and determinism (order) were considered as two complementary aspects of life. In the present paper, we will give an up to date version of the problem going beyond the dichotomy between chance and determinism. To this end, we will first see how the view on living systems has evolved from the mechanistic one of the 19th century to the one stemming from the most recent literature, where they emerge as complex systems continuously evolving through multiple interactions among their components and with the surrounding environment. We will then report on the ever increasing evidence of "friendly" co-existence in living beings between a number of "variability generators", fixed by evolution, and the "spontaneous order" derived from interactions between components. We will propose that the "disorder" generated is "benevolent" because it allows living systems to rapidly adapt to changes in the environment by continuously changing, while keeping their internal harmony.

Project Summary Report

NASA Technical Reports Server (NTRS)

Upchurch, Christopher

2011-01-01

The project, being the development of resource management applications, consisted entirely of my own effort. From deliverable requirements provided by my mentor, and some functional requirement additions generated through design reviews, It was my responsibility to implement the requested features as well as possible, given the resources available. For the most part development work consisted of database programming and functional testing using real resource data. Additional projects I worked on included some firing room console training, configuring the new NE-A microcontroller development lab network, mentoring high school CubeSat students, and managing the NE interns' component of the mentor appreciation ceremony.

Visuo-spatialWorking Memory as a Limited Resource of Cognitive Processing

NASA Astrophysics Data System (ADS)

Zimmer, Hubert D.; Münzer, Stefan; Umla-Runge, Katja

Working memory is considered a cognitive component that mainly serves two functions. It temporarily maintains information that was either perceived but is no longer present in the environment, or that was internally generated, and it supplies a work space for transforming and manipulating elements of perception and thinking. Both functions are relevant for a successful interaction with the environment and it is therefore not surprising that WM is a central topic of research in the field of general psychology. This interest is further increased by the fact that WM is seen as a limited resource that constrains cognitive performances.

Entropy Generation/Availability Energy Loss Analysis Inside MIT Gas Spring and "Two Space" Test Rigs

NASA Technical Reports Server (NTRS)

Ebiana, Asuquo B.; Savadekar, Rupesh T.; Patel, Kaushal V.

2006-01-01

The results of the entropy generation and availability energy loss analysis under conditions of oscillating pressure and oscillating helium gas flow in two Massachusetts Institute of Technology (MIT) test rigs piston-cylinder and piston-cylinder-heat exchanger are presented. Two solution domains, the gas spring (single-space) in the piston-cylinder test rig and the gas spring + heat exchanger (two-space) in the piston-cylinder-heat exchanger test rig are of interest. Sage and CFD-ACE+ commercial numerical codes are used to obtain 1-D and 2-D computer models, respectively, of each of the two solution domains and to simulate the oscillating gas flow and heat transfer effects in these domains. Second law analysis is used to characterize the entropy generation and availability energy losses inside the two solution domains. Internal and external entropy generation and availability energy loss results predicted by Sage and CFD-ACE+ are compared. Thermodynamic loss analysis of simple systems such as the MIT test rigs are often useful to understand some important features of complex pattern forming processes in more complex systems like the Stirling engine. This study is aimed at improving numerical codes for the prediction of thermodynamic losses via the development of a loss post-processor. The incorporation of loss post-processors in Stirling engine numerical codes will facilitate Stirling engine performance optimization. Loss analysis using entropy-generation rates due to heat and fluid flow is a relatively new technique for assessing component performance. It offers a deep insight into the flow phenomena, allows a more exact calculation of losses than is possible with traditional means involving the application of loss correlations and provides an effective tool for improving component and overall system performance.

76 FR 66750 - Certain Automotive GPS Navigation Systems, Components Thereof, and Products Containing Same...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-27

... INTERNATIONAL TRADE COMMISSION [DN 2850] Certain Automotive GPS Navigation Systems, Components... given that the U.S. International Trade Commission has received a complaint entitled In Re Certain Automotive GPS Navigation Systems, Components Thereof, And Products Containing Same, DN 2850; the Commission...

Components of a Measure to Describe Organizational Culture in Academic Pharmacy

PubMed Central

Rosenthal, Meagen; Holmes, Erin R.; Andrews, Brienna; Lui, Julia; Raja, Leela

2017-01-01

Objective. To develop a measure of organizational culture in academic pharmacy and identify characteristics of an academic pharmacy program that would be impactful for internal (eg, students, employees) and external (eg, preceptors, practitioners) clients of the program. Methods. A three-round Delphi procedure of 24 panelists from pharmacy schools in the U.S. and Canada generated items based on the Organizational Culture Profile (OCP), which were then evaluated and refined for inclusion in subsequent rounds. Items were assessed for appropriateness and impact. Results. The panel produced 35 items across six domains that measured organizational culture in academic pharmacy: competitiveness, performance orientation, social responsibility, innovation, emphasis on collegial support, and stability. Conclusion. The items generated require testing for validation and reliability in a large sample to finalize this measure of organizational culture. PMID:29367768

Investigation of the Makeup, Source, and Removal Strategies for Total Organic Carbon in the Oxygen Generation System Recirculation Loop

NASA Technical Reports Server (NTRS)

Bowman, Elizabeth M.; Carpenter, Joyce; Roy, Robert J.; Van Keuren, Steve; Wilson, Mark E.

2015-01-01

Since 2007, the Oxygen Generation System (OGS) on board the International Space Station (ISS) has been producing oxygen for crew respiration via water electrolysis. As water is consumed in the OGS recirculating water loop, make-up water is furnished by the ISS potable water bus. A rise in Total Organic Carbon (TOC) was observed beginning in February, 2011, which continues through the present date. Increasing TOC is of concern because the organic constituents responsible for the TOC were unknown and had not been identified; hence their impacts on the operation of the electrolytic cell stack components and on microorganism growth rates and types are unknown. Identification of the compounds responsible for the TOC increase, their sources, and estimates of their loadings in the OGA as well as possible mitigation strategies are presented.

Propulsion System Advances that Enable a Reusable Liquid Fly Back Booster (LFBB)

NASA Technical Reports Server (NTRS)

Keith, Edward L.; Rothschild, William J.

1998-01-01

This paper provides an overview of the booster propulsion system for the Liquid Fly Back Booster (LFBB). This includes, system requirements, design approach, concept of operations, reliability, safety and cost assumptions. The paper summarizes the findings of the Boeing propulsion team that has been studying the LFBB feasibility as a booster replacement for the Space Shuttle. This paper will discuss recent advances including a new generation of kerosene and oxygen rich pre-burner staged combustion cycle main rocket engines. The engine reliability and safety is expected to be much higher than current standards by adding extra operating margins into the design and normally operating the engines at 75% of engine rated power. This allows for engine out capability. The new generation of main engines operates at significantly higher chamber pressure than the prior generation of gas generator cycle engines. The oxygen rich pre-burner engine cycle, unlike the fuel rich gas generator cycle, results in internally self-cleaning firings which facilitates reusability. Maintenance is further enhanced with integrated health monitoring to improve safety and turn-around efficiency. The maintainability of the LFBB LOX / kerosene engines is being improved by designing the vehicle/engine interfaces for easy access to key engine components.

Propulsion system advances that enable a reusable Liquid Fly Back Booster (LFBB)

NASA Technical Reports Server (NTRS)

Keith, E. L.; Rothschild, W. J.

1998-01-01

This paper provides an overview of the booster propulsion system for the Liquid Fly Back Booster (LFBB). This includes, system requirements, design approach, concept of operations, reliability, safety and cost assumptions. The paper summarizes the findings of the Boeing propulsion team that has been studying the LFBB feasibility as a booster replacement for the Space Shuttle. This paper will discuss recent advances including a new generation of kerosene and oxygen rich pre-burner staged combustion cycle main rocket engines. The engine reliability and safety is expected to be much higher than current standards by adding extra operating margins into the design and normally operating the engines at 75% of engine rated power. This allows for engine out capability. The new generation of main engines operates at significantly higher chamber pressure than the prior generation of gas generator cycle engines. The oxygen rich pre-burner engine cycle, unlike the fuel rich gas generator cycle, results in internally self-cleaning firings which facilitates reusability. Maintenance is further enhanced with integrated health monitoring to improve safety and turn-around efficiency. The maintainability of the LFBB LOX/kerosene engines is being improved by designing the vehicle/engine interfaces for easy access to key engine components.

Concerning the Motion and Orientation of Flux Transfer Events Produced by Component and Antiparallel Reconnection

NASA Technical Reports Server (NTRS)

Sibeck, D. G.; Lin, R.-Q.

2011-01-01

We employ the Cooling et al. (2001) model to predict the location, orientation, motion, and signatures of flux transfer events (FTEs) generated at the solstices and equinoxes along extended subsolar component and high ]latitude antiparallel reconnection curves for typical solar wind plasma conditions and various interplanetary magnetic field (IMF) strengths and directions. In general, events generated by the two mechanisms maintain the strikingly different orientations they begin with as they move toward the terminator in opposite pairs of magnetopause quadrants. The curves along which events generated by component reconnection form bow toward the winter cusp. Events generated by antiparallel reconnection form on the equatorial magnetopause during intervals of strongly southward IMF orientation during the equinoxes, form in the winter hemisphere and only reach the dayside equatorial magnetopause during the solstices when the IMF strength is very large and the IMF points strongly southward, never reach the equatorial dayside magnetopause when the IMF has a substantial dawnward or duskward component, and never reach the equatorial flank magnetopause during intervals of northward and dawnward or duskward IMF orientation. Magnetosheath magnetic fields typically have strong components transverse to events generated by component reconnection but only weak components transverse to the axes of events generated by antiparallel reconnection. As a result, much stronger bipolar magnetic field signatures normal to the nominal magnetopause should accompany events generated by component reconnection. The results presented in this paper suggest that events generated by component reconnection predominate on the dayside equatorial and flank magnetopause for most solar wind conditions.

Location, location & size: defects close to surfaces dominate fatigue crack initiation

NASA Astrophysics Data System (ADS)

Serrano-Munoz, Itziar; Buffiere, Jean-Yves; Mokso, Rajmund; Verdu, Catherine; Nadot, Yves

2017-03-01

Metallic cast components inevitably contain defects such as shrinkage cavities which are inherent to the solidification process. Those defects are known to significantly alter the fatigue life of components. Yet very little is known, quantitatively, on the dangerosity of internal casting defects compared to surface ones. In this study, fatigue specimens containing controlled internal defects (shrinkage pores) are used to foster internal cracking. In situ fatigue tests monitored by X ray synchrotron tomography revealed that the internal nucleation and propagation of cracks was systematically overran by surface cracking initiated at castings defects up to ten times smaller than the internal ones. These findings indicate that the presence of internal defects in cast components can be tolerated to a larger extent than is allowed by nowadays standards

Location, location &size: defects close to surfaces dominate fatigue crack initiation.

PubMed

Serrano-Munoz, Itziar; Buffiere, Jean-Yves; Mokso, Rajmund; Verdu, Catherine; Nadot, Yves

2017-03-27

Metallic cast components inevitably contain defects such as shrinkage cavities which are inherent to the solidification process. Those defects are known to significantly alter the fatigue life of components. Yet very little is known, quantitatively, on the dangerosity of internal casting defects compared to surface ones. In this study, fatigue specimens containing controlled internal defects (shrinkage pores) are used to foster internal cracking. In situ fatigue tests monitored by X ray synchrotron tomography revealed that the internal nucleation and propagation of cracks was systematically overran by surface cracking initiated at castings defects up to ten times smaller than the internal ones. These findings indicate that the presence of internal defects in cast components can be tolerated to a larger extent than is allowed by nowadays standards.

Location, location & size: defects close to surfaces dominate fatigue crack initiation

PubMed Central

Serrano-Munoz, Itziar; Buffiere, Jean-Yves; Mokso, Rajmund; Verdu, Catherine; Nadot, Yves

2017-01-01

Metallic cast components inevitably contain defects such as shrinkage cavities which are inherent to the solidification process. Those defects are known to significantly alter the fatigue life of components. Yet very little is known, quantitatively, on the dangerosity of internal casting defects compared to surface ones. In this study, fatigue specimens containing controlled internal defects (shrinkage pores) are used to foster internal cracking. In situ fatigue tests monitored by X ray synchrotron tomography revealed that the internal nucleation and propagation of cracks was systematically overran by surface cracking initiated at castings defects up to ten times smaller than the internal ones. These findings indicate that the presence of internal defects in cast components can be tolerated to a larger extent than is allowed by nowadays standards PMID:28345599

Environmental and resource burdens associated with world biofuel production out to 2050: footprint components from carbon emissions and land use to waste arisings and water consumption.

PubMed

Hammond, Geoffrey P; Li, Bo

2016-09-01

Environmental or 'ecological' footprints have been widely used in recent years as indicators of resource consumption and waste absorption presented in terms of biologically productive land area [in global hectares (gha)] required per capita with prevailing technology. In contrast, 'carbon footprints' are the amount of carbon (or carbon dioxide equivalent) emissions for such activities in units of mass or weight (like kilograms per functional unit), but can be translated into a component of the environmental footprint (on a gha basis). The carbon and environmental footprints associated with the world production of liquid biofuels have been computed for the period 2010-2050. Estimates of future global biofuel production were adopted from the 2011 International Energy Agency (IEA) 'technology roadmap' for transport biofuels. This suggests that, although first generation biofuels will dominate the market up to 2020, advanced or second generation biofuels might constitute some 75% of biofuel production by 2050. The overall environmental footprint was estimated to be 0.29 billion (bn) gha in 2010 and is likely to grow to around 2.57 bn gha by 2050. It was then disaggregated into various components: bioproductive land, built land, carbon emissions, embodied energy, materials and waste, transport, and water consumption. This component-based approach has enabled the examination of the Manufactured and Natural Capital elements of the 'four capitals' model of sustainability quite broadly, along with specific issues (such as the linkages associated with the so-called energy-land-water nexus). Bioproductive land use was found to exhibit the largest footprint component (a 48% share in 2050), followed by the carbon footprint (23%), embodied energy (16%), and then the water footprint (9%). Footprint components related to built land, transport and waste arisings were all found to account for an insignificant proportion to the overall environmental footprint, together amounting to only about 2.

76 FR 12994 - In the Matter of Certain Digital Televisions and Components Thereof, and Certain Electronic...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-09

... INTERNATIONAL TRADE COMMISSION [Inv. No. 337-TA-764] In the Matter of Certain Digital Televisions and Components Thereof, and Certain Electronic Devices Having a Blu-Ray Disc Player and Components Thereof; Notice of Investigation AGENCY: U.S. International Trade Commission. ACTION: Institution of...

76 FR 13928 - Amendment to the International Traffic in Arms Regulations: Replacement Parts/Components and...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-15

... International Traffic in Arms Regulations: Replacement Parts/Components and Incorporated Articles AGENCY... incorporated articles. DATES: The Department of State will accept comments on this proposed rule until April 14... Controls Policy, Attn: Regulatory Changes--Replacement Parts/Components and Incorporated Articles, Bureau...

Failing to retain a new generation of doctors: qualitative insights from a high-income country.

PubMed

Humphries, Niamh; Crowe, Sophie; Brugha, Ruairí

2018-02-27

The failure of high-income countries, such as Ireland, to achieve a self-sufficient medical workforce has global implications, particularly for low-income, source countries. In the past decade, Ireland has doubled the number of doctors it trains annually, but because of its failure to retain doctors, it remains heavily reliant on internationally trained doctors to staff its health system. To halve its dependence on internationally trained doctors by 2030, in line with World Health Organisation (WHO) recommendations, Ireland must become more adept at retaining doctors. This paper presents findings from in-depth interviews conducted with 50 early career doctors between May and July 2015. The paper explores the generational component of Ireland's failure to retain doctors and makes recommendations for retention policy and practice. Interviews revealed that a new generation of doctors differ from previous generations in several distinct ways. Their early experiences of training and practice have been in an over-stretched, under-staffed health system and this shapes their decision to remain in Ireland, or to leave. Perhaps as a result of the distinct challenges they have faced in an austerity-constrained health system and their awareness of the working conditions available globally, they challenge the traditional view of medicine as a vocation that should be prioritised before family and other commitments. A new generation of doctors have career options that are also strongly shaped by globalisation and by the opportunities presented by emigration. Understanding the medical workforce from a generational perspective requires that the health system address the issues of concern to a new generation of doctors, in terms of working conditions and training structures and also in terms of their desire for a more acceptable balance between work and life. This will be an important step towards future-proofing the medical workforce and is essential to achieving medical workforce self-sufficiency.

Component Design Report: International Transportation Energy Demand Determinants Model

EIA Publications

2017-01-01

This Component Design Report discusses working design elements for a new model to replace the International Transportation Model (ITran) in the World Energy Projection System Plus (WEPS ) that is maintained by the U.S. Energy Information Administration. The key objective of the new International Transportation Energy Demand Determinants (ITEDD) model is to enable more rigorous, quantitative research related to energy consumption in the international transportation sectors.

Applications of neutron radiography for the nuclear power industry

DOE Office of Scientific and Technical Information (OSTI.GOV)

Craft, Aaron E.; Barton, John P.

The World Conference on Neutron Radiography (WCNR) and International Topical Meeting on Neutron Radiography (ITMNR) series have been running over 35 years. The most recent event, ITMNR-8, focused on industrial applications and was the first time this series was hosted in China. In China, more than twenty new nuclear power plants are in construction and plans have been announced to increase the nuclear capacity further by a factor of three within fifteen years. There are additional prospects in many other nations. Neutron tests were vital during previous developments of materials and components for nuclear power applications, as reported in thismore » conference series. For example a majority of the 140 papers in the Proceedings of the First WCNR are for the benefit of the nuclear power industry. Included are reviews of the diverse techniques being applied in Europe, Japan, the United States, and at many other centers. Many of those techniques are being utilized and advanced to the present time. Neutron radiography of irradiated nuclear fuel provides more comprehensive information about the internal condition of irradiated nuclear fuel than any other non-destructive technique to date. Applications include examination of nuclear waste, nuclear fuels, cladding, control elements, and other critical components. In this paper, the techniques developed and applied internationally for the nuclear power industry since the earliest years are reviewed, and the question is asked whether neutron test techniques can be of value in development of the present and future generations of nuclear power plants world-wide.« less

Interface Generation and Compositional Verification in JavaPathfinder

NASA Technical Reports Server (NTRS)

Giannakopoulou, Dimitra; Pasareanu, Corina

2009-01-01

We present a novel algorithm for interface generation of software components. Given a component, our algorithm uses learning techniques to compute a permissive interface representing legal usage of the component. Unlike our previous work, this algorithm does not require knowledge about the component s environment. Furthermore, in contrast to other related approaches, our algorithm computes permissive interfaces even in the presence of non-determinism in the component. Our algorithm is implemented in the JavaPathfinder model checking framework for UML statechart components. We have also added support for automated assume-guarantee style compositional verification in JavaPathfinder, using component interfaces. We report on the application of the presented approach to the generation of interfaces for flight software components.

Area-efficient physically unclonable function circuit architecture

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gurrieri, Thomas; Hamlet, Jason; Bauer, Todd

Generating a physically a physically unclonable function ("PUF") circuit value includes comparing each of first identification components in a first bank to each of second identification components in a second bank. A given first identification component in the first bank is not compared to another first identification component in the first bank and a given second identification component in the second bank is not compared to another second identification component in the second bank. A digital bit value is generated for each comparison made while comparing each of the first identification components to each of the second identification components. Amore » PUF circuit value is generated from the digital bit values from each comparison made.« less

Semiautomatic segmentation and follow-up of multicomponent low-grade tumors in longitudinal brain MRI studies

PubMed Central

Weizman, Lior; Sira, Liat Ben; Joskowicz, Leo; Rubin, Daniel L.; Yeom, Kristen W.; Constantini, Shlomi; Shofty, Ben; Bashat, Dafna Ben

2014-01-01

Purpose: Tracking the progression of low grade tumors (LGTs) is a challenging task, due to their slow growth rate and associated complex internal tumor components, such as heterogeneous enhancement, hemorrhage, and cysts. In this paper, the authors show a semiautomatic method to reliably track the volume of LGTs and the evolution of their internal components in longitudinal MRI scans. Methods: The authors' method utilizes a spatiotemporal evolution modeling of the tumor and its internal components. Tumor components gray level parameters are estimated from the follow-up scan itself, obviating temporal normalization of gray levels. The tumor delineation procedure effectively incorporates internal classification of the baseline scan in the time-series as prior data to segment and classify a series of follow-up scans. The authors applied their method to 40 MRI scans of ten patients, acquired at two different institutions. Two types of LGTs were included: Optic pathway gliomas and thalamic astrocytomas. For each scan, a “gold standard” was obtained manually by experienced radiologists. The method is evaluated versus the gold standard with three measures: gross total volume error, total surface distance, and reliability of tracking tumor components evolution. Results: Compared to the gold standard the authors' method exhibits a mean Dice similarity volumetric measure of 86.58% and a mean surface distance error of 0.25 mm. In terms of its reliability in tracking the evolution of the internal components, the method exhibits strong positive correlation with the gold standard. Conclusions: The authors' method provides accurate and repeatable delineation of the tumor and its internal components, which is essential for therapy assessment of LGTs. Reliable tracking of internal tumor components over time is novel and potentially will be useful to streamline and improve follow-up of brain tumors, with indolent growth and behavior. PMID:24784396

On the coupled evolution of oceanic internal waves and quasi-geostrophic flow

NASA Astrophysics Data System (ADS)

Wagner, Gregory LeClaire

Oceanic motion outside thin boundary layers is primarily a mixture of quasi-geostrophic flow and internal waves with either near-inertial frequencies or the frequency of the semidiurnal lunar tide. This dissertation seeks a deeper understanding of waves and flow through reduced models that isolate their nonlinear and coupled evolution from the Boussinesq equations. Three physical-space models are developed: an equation that describes quasi-geostrophic evolution in an arbitrary and prescribed field of hydrostatic internal waves; a three-component model that couples quasi-geostrophic flow to both near-inertial waves and the near-inertial second harmonic; and a model for the slow evolution of hydrostatic internal tides in quasi-geostrophic flow of near-arbitrary scale. This slow internal tide equation opens the path to a coupled model for the energetic interaction of quasi-geostrophic flow and oceanic internal tides. Four results emerge. First, the wave-averaged quasi-geostrophic equation reveals that finite-amplitude waves give rise to a mean flow that advects quasi-geostrophic potential vorticity. Second is the definition of a new material invariant: Available Potential Vorticity, or APV. APV isolates the part of Ertel potential vorticity available for balanced-flow evolution in Eulerian frames and proves necessary in the separating waves and quasi-geostrophic flow. The third result, hashed out for near-inertial waves and quasi-geostrophic flow, is that wave-flow interaction leads to energy exchange even under conditions of weak nonlinearity. For storm-forced oceanic near-inertial waves the interaction often energizes waves at the expense of flow. We call this extraction of balanced quasi-geostrophic energy 'stimulated generation' since it requires externally-forced rather than spontaneously-generated waves. The fourth result is that quasi-geostrophic flow can encourage or 'catalyze' a nonlinear interaction between a near-inertial wave field and its second harmonic that transfers energy to the small near-inertial vertical scales of wave breaking and mixing.

High gliding fluid power generation system with fluid component separation and multiple condensers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mahmoud, Ahmad M; Lee, Jaeseon; Radcliff, Thomas D

2014-10-14

An example power generation system includes a vapor generator, a turbine, a separator and a pump. In the separator, the multiple components of the working fluid are separated from each other and sent to separate condensers. Each of the separate condensers is configured for condensing a single component of the working fluid. Once each of the components condense back into a liquid form they are recombined and exhausted to a pump that in turn drives the working fluid back to the vapor generator.

Transport Properties of Bulk Thermoelectrics—An International Round-Robin Study, Part I: Seebeck Coefficient and Electrical Resistivity

NASA Astrophysics Data System (ADS)

Wang, Hsin; Porter, Wallace D.; Böttner, Harald; König, Jan; Chen, Lidong; Bai, Shengqiang; Tritt, Terry M.; Mayolet, Alex; Senawiratne, Jayantha; Smith, Charlene; Harris, Fred; Gilbert, Patricia; Sharp, Jeff W.; Lo, Jason; Kleinke, Holger; Kiss, Laszlo

2013-04-01

Recent research and development of high-temperature thermoelectric materials has demonstrated great potential for converting automobile exhaust heat directly into electricity. Thermoelectrics based on classic bismuth telluride have also started to impact the automotive industry by enhancing air-conditioning efficiency and integrated cabin climate control. In addition to engineering challenges of making reliable and efficient devices to withstand thermal and mechanical cycling, the remaining issues in thermoelectric power generation and refrigeration are mostly materials related. The dimensionless figure of merit, ZT, still needs to be improved from the current value of 1.0 to 1.5 to above 2.0 to be competitive with other alternative technologies. In the meantime, the thermoelectric community could greatly benefit from the development of international test standards, improved test methods, and better characterization tools. Internationally, thermoelectrics have been recognized by many countries as a key component for improving energy efficiency. The International Energy Agency (IEA) group under the Implementing Agreement for Advanced Materials for Transportation (AMT) identified thermoelectric materials as an important area in 2009. This paper is part I of the international round-robin testing of transport properties of bulk thermoelectrics. The main foci in part I are the measurement of two electronic transport properties: Seebeck coefficient and electrical resistivity.

Use of individualized learning plans among fourth-year sub-interns in pediatrics and internal medicine.

PubMed

Shepard, Michelle E; Sastre, Elizabeth A; Davidson, Mario A; Fleming, Amy E

2012-01-01

Individualized Learning Plans (ILPs) are an effective tool for promoting self-directed learning among residents. However, no literature details ILP use among medical students. Fifty fourth-year sub-interns in pediatrics and internal medicine created ILPs, including a self-assessment of strengths and weaknesses based on ACGME core competencies and the setting of learning objectives. During weekly follow-up meetings with faculty mentors and peers, students discussed challenges and revised goals. Upon completion of the rotation, students completed a survey of Likert-scale questions addressing satisfaction with and perceived utility of ILP components. Students most often self-identified strengths in the areas of Professionalism and Interpersonal and Communication Skills and weaknesses in Patient Care and Systems-Based Practice. Eighty-two percent set at least one learning objective in an identified area of weakness. Students expressed high confidence in their abilities to create achievable learning objectives and to generate strategies to meet those objectives. Students agreed that discussions during group meetings were meaningful, and they identified the setting learning objectives and weekly meetings as the most important elements of the exercise. Fourth-year sub-interns reported that ILPs helped them to accomplish rotation goals, with the setting of learning objectives and weekly discussions being the most useful elements.

[Discomfort associated with dental extraction surgery and development of a questionnaire (QCirDental). Part I: Impacts and internal consistency].

PubMed

Bortoluzzi, Marcelo Carlos; Martins, Luciana Dorochenko; Takahashi, André; Ribeiro, Bianca; Martins, Ligiane; Pinto, Marcia Helena Baldani

2018-01-01

The scope of this study was to develop and validate a questionnaire (QCirDental) to measure the impacts associated with dental extraction surgery. The QCirDental questionnaire was developed in two steps; (1) question and item generation and selection, and (2) pretest of the questionnaire with evaluation of the its measurement properties (internal consistency and responsiveness). The sample was composed of 123 patients. None of the patients had any difficulty in understanding the QCirDental. The instrument was found to have excellent internal consistency with Cronbach's alpha reliability coefficient of 0.83. The principal component analysis (Kaiser-Meyer-Olkin Measure of Sampling Adequacy 0,72 and Bartlett's Test of Sphericity with p < 0.001) showed six (6) dimensions explaining 67.5% of the variance. The QCirDental presented excellent internal consistency, being a questionnaire that is easy to read and understand with adequate semantic and content validity. More than 80% of the patients who underwent dental extraction reported some degree of discomfort within the perioperative period which highlights the necessity to assess the quality of care and impacts of dental extraction surgery.

EMMA—mouse mutant resources for the international scientific community

PubMed Central

Wilkinson, Phil; Sengerova, Jitka; Matteoni, Raffaele; Chen, Chao-Kung; Soulat, Gaetan; Ureta-Vidal, Abel; Fessele, Sabine; Hagn, Michael; Massimi, Marzia; Pickford, Karen; Butler, Richard H.; Marschall, Susan; Mallon, Ann-Marie; Pickard, Amanda; Raspa, Marcello; Scavizzi, Ferdinando; Fray, Martin; Larrigaldie, Vanessa; Leyritz, Johan; Birney, Ewan; Tocchini-Valentini, Glauco P.; Brown, Steve; Herault, Yann; Montoliu, Lluis; de Angelis, Martin Hrabé; Smedley, Damian

2010-01-01

The laboratory mouse is the premier animal model for studying human disease and thousands of mutants have been identified or produced, most recently through gene-specific mutagenesis approaches. High throughput strategies by the International Knockout Mouse Consortium (IKMC) are producing mutants for all protein coding genes. Generating a knock-out line involves huge monetary and time costs so capture of both the data describing each mutant alongside archiving of the line for distribution to future researchers is critical. The European Mouse Mutant Archive (EMMA) is a leading international network infrastructure for archiving and worldwide provision of mouse mutant strains. It operates in collaboration with the other members of the Federation of International Mouse Resources (FIMRe), EMMA being the European component. Additionally EMMA is one of four repositories involved in the IKMC, and therefore the current figure of 1700 archived lines will rise markedly. The EMMA database gathers and curates extensive data on each line and presents it through a user-friendly website. A BioMart interface allows advanced searching including integrated querying with other resources e.g. Ensembl. Other resources are able to display EMMA data by accessing our Distributed Annotation System server. EMMA database access is publicly available at http://www.emmanet.org. PMID:19783817

Interpersonal synergies: static prehension tasks performed by two actors.

PubMed

Solnik, Stanislaw; Reschechtko, Sasha; Wu, Yen-Hsun; Zatsiorsky, Vladimir M; Latash, Mark L

2016-08-01

We investigated multidigit synergies stabilizing components of the resultant force vector during joint performance of a static prehension task by two persons as compared to similar tasks performed by a single person using both hands. Subjects transferred the instrumented handle from the right hand to the left hand (one-person condition) or passed that handle to another person (two-person condition) while keeping the handle's position and orientation stationary. Only three digits were involved per hand, the thumb, the index finger, and the middle finger; the forces and moments produced by the digits were measured by six-component sensors. We estimated the performance-stabilizing synergies within the uncontrolled manifold framework by quantifying the intertrial variance structure of digit forces and moments. The analysis was performed at three levels: between hands, between virtual finger and virtual thumb (imagined digits producing the same mechanical variables as the corresponding actual digits combined) produced by the two hands (in both interpersonal and intrapersonal conditions), and between the thumb and virtual finger for one hand only. Additionally, we performed correlation and phase synchronization analyses of resultant tangential forces and internal normal forces. Overall, the one-person conditions were characterized by higher amount of intertrial variance that did not affect resultant normal force components, higher internal components of normal forces, and stronger synchronization of the normal forces generated by the hands. Our observations suggest that in two-person tasks, when participants try to achieve a common mechanical outcome, the performance-stabilizing synergies depend on non-visual information exchange, possibly via the haptic and proprioceptive systems. Therefore, synergies quantified in tasks using visual feedback only may not be generalizable to more natural tasks.

The representational dynamics of remembered projectile locations.

PubMed

De Sá Teixeira, Nuno Alexandre; Hecht, Heiko; Oliveira, Armando Mónica

2013-12-01

When people are instructed to locate the vanishing location of a moving target, systematic errors forward in the direction of motion (M-displacement) and downward in the direction of gravity (O-displacement) are found. These phenomena came to be linked with the notion that physical invariants are embedded in the dynamic representations generated by the perceptual system. We explore the nature of these invariants that determine the representational mechanics of projectiles. By manipulating the retention intervals between the target's disappearance and the participant's responses, while measuring both M- and O-displacements, we were able to uncover a representational analogue of the trajectory of a projectile. The outcomes of three experiments revealed that the shape of this trajectory is discontinuous. Although the horizontal component of such trajectory can be accounted for by perceptual and oculomotor factors, its vertical component cannot. Taken together, the outcomes support an internalization of gravity in the visual representation of projectiles.

Migration of cemented femoral components after THR. Roentgen stereophotogrammetric analysis.

PubMed

Kiss, J; Murray, D W; Turner-Smith, A R; Bithell, J; Bulstrode, C J

1996-09-01

We studied the migration of 58 cemented Hinek femoral components for total hip replacement, using roentgen stereophotogrammetric analysis over four years. The implants migrated faster during the first year than subsequently, and the pattern of migration in the second period was very different. During the first year they subsided, tilted into varus and internally rotated. After this there was slow distal migration with no change in orientation. None of the prostheses has yet failed. The early migration is probably caused by resorption of bone damaged by surgical trauma or the heat generated by the polymerisation of bone cement. Later migration may be due to creep in the bone cement or the surrounding fibrous membrane. The prosthesis which we studied allows the preservation of some of the femoral neck, and comparison with published migration studies of the Charnley stem suggests that this decreases rotation and may help to prevent loosening.

Skylab extravehicular mobility unit thermal simulator

NASA Technical Reports Server (NTRS)

Hixon, C. W.; Phillips, M. A.

1974-01-01

The analytical methods, thermal model, and user's instructions for the Skylab Extravehicular Mobility Unit (SEMU) routine are presented. This digital computer program was developed for detailed thermal performance predictions of the SEMU on the NASA-JSC Univac 1108 computer system. It accounts for conductive, convective, and radiant heat transfer as well as fluid flow and special component characterization. The program provides thermal performance predictions for a 967 node thermal model in one thirty-sixth (1/36) of mission time when operated at a calculating interval of three minutes (mission time). The program has the operational flexibility to: (1) accept card or magnetic tape data input for the thermal model describing the SEMU structure, fluid systems, crewman and component performance, (2) accept card and/or magnetic tape input of internally generated heat and heat influx from the space environment, and (3) output tabular or plotted histories of temperature, flow rates, and other parameters describing system operating modes.

Beryllium processing technology review for applications in plasma-facing components

DOE Office of Scientific and Technical Information (OSTI.GOV)

Castro, R.G.; Jacobson, L.A.; Stanek, P.W.

1993-07-01

Materials research and development activities for the International Thermonuclear Experimental Reactor (ITER), i.e., the next generation fusion reactor, are investigating beryllium as the first-wall containment material for the reactor. Important in the selection of beryllium is the ability to process, fabricate and repair beryllium first-wall components using existing technologies. Two issues that will need to be addressed during the engineering design activity will be the bonding of beryllium tiles in high-heat-flux areas of the reactor, and the in situ repair of damaged beryllium tiles. The following review summarizes the current technology associated with welding and joining of beryllium to itselfmore » and other materials, and the state-of-the-art in plasma-spray technology as an in situ repair technique for damaged beryllium tiles. In addition, a review of the current status of beryllium technology in the former Soviet Union is also included.« less

The Coach-Athlete Relationship Questionnaire (CART-Q): development and initial validation.

PubMed

Jowett, Sophia; Ntoumanis, Nikos

2004-08-01

The purpose of the present study was to develop and validate a self-report instrument that measures the nature of the coach-athlete relationship. Jowett et al.'s (Jowett & Meek, 2000; Jowett, in press) qualitative case studies and relevant literature were used to generate items for an instrument that measures affective, cognitive, and behavioral aspects of the coach-athlete relationship. Two studies were carried out in an attempt to assess content, predictive, and construct validity, as well as internal consistency, of the Coach-Athlete Relationship Questionnaire (CART-Q), using two independent British samples. Principal component analysis and confirmatory factor analysis were used to reduce the number of items, identify principal components, and confirm the latent structure of the CART-Q. Results supported the multidimensional nature of the coach-athlete relationship. The latent structure of the CART-Q was underlined by the latent variables of coaches' and athletes' Closeness (emotions), Commitment (cognitions), and Complementarity (behaviors).

Characterization of the powertrain components for a hybrid quadricycle

NASA Astrophysics Data System (ADS)

De Santis, M.; Agnelli, S.; Silvestri, L.; Di Ilio, G.; Giannini, O.

2016-06-01

This paper presents the experimental characterization of a prototyping hybrid electric quadricycle, which is equipped with two independently actuated hub (in-wheel) motors and powered by a 51 V 132 Ah LiFeYPO4 battery pack. Such a vehicle employs two hub motors located in the rear axles in order to independently drive/brake the rear wheels; such architecture allows to implement a torque vectoring system to improve the vehicle dynamics. Due to its actuation flexibility, energy efficiency and performance potentials, this architecture is one of the promising powertrain design for electric quadricycle. Experimental data obtained from measurements on the vehicle powertrain components going from the battery pack to the inverter and to the in-wheel motor were employed to generate the hub motor torque response and power efficiency maps in both driving and regenerative braking modes. Furthermore, the vehicle is equipped with a gasoline internal combustion engine as range extender whose efficiency was also characterized.

Aerosol generation and characterization of multi-walled carbon nanotubes exposed to cells cultured at the air-liquid interface.

PubMed

Polk, William W; Sharma, Monita; Sayes, Christie M; Hotchkiss, Jon A; Clippinger, Amy J

2016-04-23

Aerosol generation and characterization are critical components in the assessment of the inhalation hazards of engineered nanomaterials (NMs). An extensive review was conducted on aerosol generation and exposure apparatus as part of an international expert workshop convened to discuss the design of an in vitro testing strategy to assess pulmonary toxicity following exposure to aerosolized particles. More specifically, this workshop focused on the design of an in vitro method to predict the development of pulmonary fibrosis in humans following exposure to multi-walled carbon nanotubes (MWCNTs). Aerosol generators, for dry or liquid particle suspension aerosolization, and exposure chambers, including both commercially available systems and those developed by independent researchers, were evaluated. Additionally, characterization methods that can be used and the time points at which characterization can be conducted in order to interpret in vitro exposure results were assessed. Summarized below is the information presented and discussed regarding the relevance of various aerosol generation and characterization techniques specific to aerosolized MWCNTs exposed to cells cultured at the air-liquid interface (ALI). The generation of MWCNT aerosols relevant to human exposures and their characterization throughout exposure in an ALI system is critical for extrapolation of in vitro results to toxicological outcomes in humans.

Electronics and Software Engineer for Robotics Project Intern

NASA Technical Reports Server (NTRS)

Teijeiro, Antonio

2017-01-01

I was assigned to mentor high school students for the 2017 First Robotics Competition. Using a team based approach, I worked with the students to program the robot and applied my electrical background to build the robot from start to finish. I worked with students who had an interest in electrical engineering to teach them about voltage, current, pulse width modulation, solenoids, electromagnets, relays, DC motors, DC motor controllers, crimping and soldering electrical components, Java programming, and robotic simulation. For the simulation, we worked together to generate graphics files, write simulator description format code, operate Linux, and operate SOLIDWORKS. Upon completion of the FRC season, I transitioned over to providing full time support for the LCS hardware team. During this phase of my internship I helped my co-intern write test steps for two networking hardware DVTs , as well as run cables and update cable running lists.

Stability of silk and collagen protein materials in space.

PubMed

Hu, Xiao; Raja, Waseem K; An, Bo; Tokareva, Olena; Cebe, Peggy; Kaplan, David L

2013-12-05

Collagen and silk materials, in neat forms and as silica composites, were flown for 18 months on the International Space Station [Materials International Space Station Experiment (MISSE)-6] to assess the impact of space radiation on structure and function. As natural biomaterials, the impact of the space environment on films of these proteins was investigated to understand fundamental changes in structure and function related to the future utility in materials and medicine in space environments. About 15% of the film surfaces were etched by heavy ionizing particles such as atomic oxygen, the major component of the low-Earth orbit space environment. Unexpectedly, more than 80% of the silk and collagen materials were chemically crosslinked by space radiation. These findings are critical for designing next-generation biocompatible materials for contact with living systems in space environments, where the effects of heavy ionizing particles and other cosmic radiation need to be considered.

Stability of Silk and Collagen Protein Materials in Space

PubMed Central

Hu, Xiao; Raja, Waseem K.; An, Bo; Tokareva, Olena; Cebe, Peggy; Kaplan, David L.

2013-01-01

Collagen and silk materials, in neat forms and as silica composites, were flown for 18 months on the International Space Station [Materials International Space Station Experiment (MISSE)-6] to assess the impact of space radiation on structure and function. As natural biomaterials, the impact of the space environment on films of these proteins was investigated to understand fundamental changes in structure and function related to the future utility in materials and medicine in space environments. About 15% of the film surfaces were etched by heavy ionizing particles such as atomic oxygen, the major component of the low-Earth orbit space environment. Unexpectedly, more than 80% of the silk and collagen materials were chemically crosslinked by space radiation. These findings are critical for designing next-generation biocompatible materials for contact with living systems in space environments, where the effects of heavy ionizing particles and other cosmic radiation need to be considered. PMID:24305951

Dual-phase-shift spherical Fizeau interferometer for reduction of noise due to internally scattered light

NASA Astrophysics Data System (ADS)

Kumagai, Toshiki; Hibino, Kenichi; Nagaike, Yasunari

2017-03-01

Internally scattered light in a Fizeau interferometer is generated from dust, defects, imperfect coating of the optical components, and multiple reflections inside the collimator lens. It produces additional noise fringes in the observed interference image and degrades the repeatability of the phase measurement. A method to reduce the phase measurement error is proposed, in which the test surface is mechanically translated between each phase measurement in addition to an ordinary phase shift of the reference surface. It is shown that a linear combination of several measured phases at different test surface positions can reduce the phase errors caused by the scattered light. The combination can also compensate for the nonuniformity of the phase shift that occurs in spherical tests. A symmetric sampling of the phase measurements can cancel the additional primary spherical aberrations that occur when the test surface is out of the null position of the confocal configuration.

77 FR 5275 - Certain Ink Application Devices and Components Thereof and Methods of Using the Same; Receipt of...

Federal Register 2010, 2011, 2012, 2013, 2014

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... INTERNATIONAL TRADE COMMISSION [Inv. No. 337-TA-751] In the Matter of Certain Turbomachinery Blades, Engines and Components Thereof; Notice of Investigation AGENCY: U.S. International Trade... that a complaint was filed with the U.S. International Trade Commission on November 5, 2010, under...

On generation and evolution of seaward propagating internal solitary waves in the northwestern South China Sea

NASA Astrophysics Data System (ADS)

Xu, Jiexin; Chen, Zhiwu; Xie, Jieshuo; Cai, Shuqun

2016-03-01

In this paper, the generation and evolution of seaward propagating internal solitary waves (ISWs) detected by satellite image in the northwestern South China Sea (SCS) are investigated by a fully nonlinear, non-hydrostatic, three-dimensional Massachusetts Institute of Technology general circulation model (MITgcm). The three-dimensional (3D) modeled ISWs agree favorably with those by satellite image, indicating that the observed seaward propagating ISWs may be generated by the interaction of barotropic tidal flow with the arc-like continental slope south of Hainan Island. Though the tidal current is basically in east-west direction, different types of internal waves are generated by tidal currents flowing over the slopes with different shaped shorelines. Over the slope where the shoreline is straight, only weak internal tides are generated; over the slope where the shoreline is seaward concave, large-amplitude internal bores are generated, and since the concave isobaths of the arc-like continental slope tend to focus the baroclinic tidal energy which is conveyed to the internal bores, the internal bores can efficiently disintegrate into a train of rank-ordered ISWs during their propagation away from the slope; while over the slope where the shoreline is seaward convex, no distinct internal tides are generated. It is also implied that the internal waves over the slope are generated due to mixed lee wave mechanism. Furthermore, the effects of 3D model, continental slope curvature, stratification, rotation and tidal forcing on the generation of ISWs are discussed, respectively. It is shown that, the amplitude and phase speed of ISWs derived from a two-dimensional (2D) model are smaller than those from the 3D one, and the 3D model has an advantage over 2D one in simulating the ISWs generated by the interaction between tidal currents and 3D curved continental slope; the reduced continental slope curvature hinders the extension of ISW crestline; both weaker stratification and rotation suppress the generation of ISWs; and the width of ISW crestline generated by K1 tidal harmonic is longer than that by M2 tidal harmonic.

Numerical investigation of wake-collapse internal waves generated by a submerged moving body

NASA Astrophysics Data System (ADS)

Liang, Jianjun; Du, Tao; Huang, Weigen; He, Mingxia

2017-07-01

The state-of-the-art OpenFOAM technology is used to develop a numerical model that can be devoted to numerically investigating wake-collapse internal waves generated by a submerged moving body. The model incorporates body geometry, propeller forcing, and stratification magnitude of seawater. The generation mechanism and wave properties are discussed based on model results. It was found that the generation of the wave and its properties depend greatly on the body speed. Only when that speed exceeds some critical value, between 1.5 and 4.5 m/s, can the moving body generate wake-collapse internal waves, and with increases of this speed, the time of generation advances and wave amplitude increases. The generated wake-collapse internal waves are confirmed to have characteristics of the second baroclinic mode. As the body speed increases, wave amplitude and length increase and its waveform tends to take on a regular sinusoidal shape. For three linearly temperature-stratified profiles examined, the weaker the stratification, the stronger the wake-collapse internal wave.

Are maternal mitochondria the selfish entities that are masters of the cells of eukaryotic multicellular organisms?

PubMed Central

Barlow, Peter W; Baldelli, E; Baluška, Frantisek

2009-01-01

The Energide concept, as well as the endosymbiotic theory of eukaryotic cell organization and evolution, proposes that present-day cells of eukaryotic organisms are mosaics of specialized and cooperating units, or organelles. Some of these units were originally free-living prokaryotes, which were engulfed during evolutionary time. Mitochondria represent one of these types of previously independent organisms, the Energide, is another type. This new perspective on the organization of the cell has been further expanded to reveal the concept of a public milieu, the cytosol, in which Energides and mitochondria live, each with their own private internal milieu. The present paper discusses how the endosymbiotic theory implicates a new hypothesis about the hierarchical and communicational organization of the integrated prokaryotic components of the eukaryotic cell and provides a new angle from which to consider the theory of evolution and its bearing upon cellular complexity. Thus, it is proposed that the “selfish gene” hypothesis of Dawkins1 is not the only possible perspective for comprehending genomic and cellular evolution. Our proposal is that maternal mitochondria are the selfish “master” entities of the eukaryotic cell with respect not only to their propagation from cell-to-cell and from generation-to-generation but also to their regulation of all other cellular functions. However, it should be recognized that the concept of “master” and “servant” cell components is a metaphor; in present-day living organisms their organellar components are considered to be interdependent and inseparable. PMID:19513277

Low Cost Manufacturing Approach of High Temperature PMC Components

NASA Technical Reports Server (NTRS)

Kannmacher, Kevin

1997-01-01

The overall objective is to develop a satisfactory sheet molding compound (SMC) of a high temperature polyimide, such as PMR-11-50, VCAP-75, or NB2-76, and to develop compression molding processing parameters for a random, chopped fiber, high temperature, sheet molding compound that will be more affordable than the traditional hand lay-up fabrication methods. Compression molding will reduce manufacturing costs of composites by: (1) minimizing the conventional machining required after fabrication due to the use of full 360 deg matched tooling, (2) reducing fabrication time by minimizing the intensive hand lay-up operations associated with individual ply fabrication techniques, such as ply orientation and ply count and (3) possibly reducing component mold time by advanced B-staging prior to molding. This program is an integral part of Allison's T406/AE engine family's growth plan, which will utilize technologies developed under NASA's Sub-sonic Transport (AST) programs, UHPTET initiatives, and internally through Allison's IR&D projects. Allison is aggressively pursuing this next generation of engines, with both commercial and military applications, by reducing the overall weight of the engine through the incorporation of advanced, lightweight, high temperature materials, such as polymer matrix composites. This infusion of new materials into the engine is also a major factor in reducing engine cost because it permits the use of physically smaller structural components to achieve the same thrust levels as the generation that it replaced. A lighter, more efficient propulsion system translates to a substantial cost and weight savings to an airframe's structure.

Viewing ISS Data in Real Time via the Internet

NASA Technical Reports Server (NTRS)

Myers, Gerry; Chamberlain, Jim

2004-01-01

EZStream is a computer program that enables authorized users at diverse terrestrial locations to view, in real time, data generated by scientific payloads aboard the International Space Station (ISS). The only computation/communication resource needed for use of EZStream is a computer equipped with standard Web-browser software and a connection to the Internet. EZStream runs in conjunction with the TReK software, described in a prior NASA Tech Briefs article, that coordinates multiple streams of data for the ground communication system of the ISS. EZStream includes server components that interact with TReK within the ISS ground communication system and client components that reside in the users' remote computers. Once an authorized client has logged in, a server component of EZStream pulls the requested data from a TReK application-program interface and sends the data to the client. Future EZStream enhancements will include (1) extensions that enable the server to receive and process arbitrary data streams on its own and (2) a Web-based graphical-user-interface-building subprogram that enables a client who lacks programming expertise to create customized display Web pages.

US Integrated Ocean Observing System (IOOS°): Delivering Benefits to Science and Society

NASA Astrophysics Data System (ADS)

Willis, Z. S.

2011-12-01

The United States Integrated Ocean Observing System (IOOS°) is a user-driven, coordinated network of people, organizations, and technology that generate and disseminate continuous data about our coastal waters, Great Lakes, and oceans supported by strong research and development activities. IOOS° is our Eyes on our Oceans, Coasts and Great Lakes that enable the United States to track, predict, manage, and adapt to changes in our marine environment and deliver critical information to decision makers to improve safety, enhance our economy and protect our environment. IOOS provides a major shift in the approach to ocean observing by drawing together the vast network of disparate federal and non-federal observing systems to produce a cohesive suite of data, information, and products on a sufficient geographic and temporal scale to support decision-making. Two interdependent components constitute the U.S. IOOS: (1) the global ocean component, and (2) the coastal component. The strength of IOOS is in its partnerships, starting with the federal agencies, the partnerships extend internationally for the global component and to the local level for the coastal component. The coastal component includes the national set of observations for the U.S. Ocean, Coasts and Great Lakes, a network of Regional Associations that are establishing Regional Coastal Ocean Observing Systems (RCOOS) and the Alliance for Coastal Technologies (ACT). The U.S. IOOS is our nation's contribution to the Global Ocean Observing System (GOOS) - the ocean component of the Global Earth Observation System of Systems (GEOSS).

All-solid-state, synchronously pumped, ultrafast BaWO4 Raman laser with long and short Raman shifts generating at 1180, 1225, and 1323 nm

NASA Astrophysics Data System (ADS)

Frank, Milan; Jelínek, Michal; Kubeček, Václav; Ivleva, Lyudmila I.; Zverev, Petr G.; Smetanin, Sergei

2017-12-01

A lot of attention is currently focused on synchronously pumped, extra-cavity crystalline Raman lasers generating one or two Stokes Raman components in KGW or diamond Raman-active crystals, and also generating additional components of stimulated polariton scattering in lithium niobate crystal having both cubic and quadratic nonlinearities. In this contribution we report on generation of more than two Stokes components of stimulated Raman scattering with different Raman shifts in the all-solid-state, synchronously pumped, extra-cavity Raman laser based on the Raman-active a-cut BaWO4 crystal excited by a mode-locked, 220 nJ, 36 ps, 150 MHz diode sidepumped Nd:GdVO4 laser generating at the wavelength of 1063 nm. Excitation by the pumping radiation polarized along the BaWO4 crystal optical axis resulted in the Raman generation with not only usual (925cm - 1), but also additional (332cm - 1) Raman shift. Besides the 1180-nm first and 1323 nm second Stokes components with the Raman shift of 925cm - 1 from the 1063nm fundamental laser wavelength, we have achieved generation of the additional 1227 nm Raman component with different Raman shift of 332cm - 1 from the 1180nm component. At the 1227 nm component the strongest 12-times pulse shortening from 36ps down to 3ps was obtained due to shorter dephasing time of this additional Raman line (3ps for the 332-cm - 1 line instead of 6.5ps for the 925cm - 1 line). It has to be also noted that the 1225 nm generation is intracavity pumped by the 1179 nm first Stokes component resulting in the strongest pulse shortening close to the 332cm -1 line dephasing time (3ps). Slope efficiency of three Stokes components generation exceeded 20%.

International Cooperation. The Next Generation. Report of the DSMC 1990 - 1991 Military Research Fellows

DTIC Science & Technology

1991-09-01

Maintaining Goal Congruence International Cooperation-the Next Generation ENDNOTES 1. Wolfgang Flume and David Swa, "British Aerospace-Leading...Program Management Questionnaire Report. Michael G. Krause , DSMC internal document, May 1989- 10. Bonn Seminar on Armaments cooperation, proceedings, w...Appendix K 154 International Cooperation-the Next Generation Dudney, Robert S., "The Electronics Industry Flume, Wolfgang , "Electronics for the Ger- Is

An Exemplary Case of Promotion Activities and Taste Panels from the Perspective of Tobacco Control

PubMed Central

Mutlu, Erdem İlker; Seydioğulları, Mustafa; Aslan, Dilek

2015-01-01

The Framework Convention on Tobacco Control is a multilateral international agreement which has been generated to protect the health of nationals and nations against the hazards/risks of tobacco and its products. All high contracting parties to the Convention undertake the international responsibility to fulfill all the requirements of the Convention’s articles in national legal systems. The Framework Convention on Tobacco Control has a considerable place among other international conventions on health. Within the self-executing desing/system of the Convention, a vital regulation focuses on banning the advertisement, promotion, and sponsorship of tobacco products. Because they are one of the various components of tobacco advertisement, promotion, and sponsorship, taste panels should be assessed within the content of the Convention. Thus, banning taste panel activities is an important step in tobacco control and it is one of the basic areas where medical and law sciences should collaborate. In this article, a comprehensive frame has been drawn to the issue and recommendations have been developed for the future. PMID:29404102

On the generation and evolution of internal solitary waves in the southern Red Sea

NASA Astrophysics Data System (ADS)

Guo, Daquan; Zhan, Peng; Kartadikaria, Aditya; Akylas, Triantaphyllos; Hoteit, Ibrahim

2015-04-01

Satellite observations recently revealed the existence of trains of internal solitary waves in the southern Red Sea between 16.0°N and 16.5°N, propagating from the centre of the domain toward the continental shelf [Da silva et al., 2012]. Given the relatively weak tidal velocity in this area and their generation in the central of the domain, Da Silva suggested three possible mechanisms behind the generation of the waves, namely Resonance and disintegration of interfacial tides, Generation of interfacial tides by impinging, remotely generated internal tidal beams and for geometrically focused and amplified internal tidal beams. Tide analysis based on tide stations data and barotropic tide model in the Red Sea shows that tide is indeed very weak in the centre part of the Red Sea, but it is relatively strong in the northern and southern parts (reaching up to 66 cm/s). Together with extreme steep slopes along the deep trench, it provides favourable conditions for the generation of internal solitary in the southern Red Sea. To investigate the generation mechanisms and study the evolution of the internal waves in the off-shelf region of the southern Red Sea we have implemented a 2-D, high-resolution and non-hydrostatic configuration of the MIT general circulation model (MITgcm). Our simulations reproduce well that the generation process of the internal solitary waves. Analysis of the model's output suggests that the interaction between the topography and tidal flow with the nonlinear effect is the main mechanism behind the generation of the internal solitary waves. Sensitivity experiments suggest that neither tidal beam nor the resonance effect of the topography is important factor in this process.

Click-evoked auditory brainstem responses and autism spectrum disorder: A meta-analytic review.

PubMed

Talge, Nicole M; Tudor, Brooke M; Kileny, Paul R

2018-06-01

Behavior does not differentiate ASD risk prior to 12 months of age, but biomarkers may inform risk before symptoms emerge. Click-evoked auditory brainstem responses (ABRs) may be worth consideration due to their measurement properties (noninvasiveness; reliability) and conceptual features (well-characterized neural generators), but participant characteristics and assessment protocols vary considerably across studies. Our goal is to perform a meta-analysis of the association between ABRs and ASD. Following an electronic database search (PubMed, Medline, PsycInfo, PsycArticles), we included papers that were written in English, included ASD and typically-developing (TD) groups, and reported the information needed to calculate standardized mean differences (Hedges's g) for at least one ABR latency component (I, III, V, I-III, III-V, I-V). We weighted and averaged effect sizes across conditions and subsets of participants to yield one estimate per component per study. We then performed random-effects regressions to generate component-specific estimates. ASD was associated with longer ABR latencies for Waves III (g = 0.5, 95% CI 0.1, 0.9), V (g = 0.7, 95% CI 0.3, 1.1), I-III (g = 0.7, 95% CI 0.2, 1.2), and I-V (g = 0.6, 95% CI 0.2, 1.0). All components showed significant heterogeneity. Associations were strongest among participants ≤8 years of age and those without middle ear abnormalities or elevated auditory thresholds. In sum, associations between ABRs and ASD are medium-to-large in size, but exhibit heterogeneity. Identifying sources of heterogeneity is challenging, however, due to power limitations and co-occurrence of sample/design characteristics across studies. Research addressing the above limitations is crucial to determining the etiologic and/or prognostic value of ABRs for ASD. Autism Res 2018, 11: 916-927. © 2018 International Society for Autism Research, Wiley Periodicals, Inc. Auditory brainstem responses (ABR) may be associated with ASD, but participant characteristics and assessment protocols vary considerably across individual studies. Our goal is to combine the results across these studies to facilitate clarity on the topic. Doing so represents a first step in evaluating whether ABRs yield potential for informing the etiology of ASD risk and/or ASD symptom profiles. © 2018 International Society for Autism Research, Wiley Periodicals, Inc.

Propulsion and Energetics Panel Working Group 14 on Suitable Averaging Techniques in Non-Uniform Internal Flows

DTIC Science & Technology

1983-06-01

PANEL WORKING GROUP 14 on SUITABLE AVERAGING TECHNIQUES IN NON-UNIFORM INTERNAL FLOWS Edited by M.Pianko Office National d’Etudes et de...d’Etudes et de Recherches Aerospatiales Pratt and Whitney Government Products Division Rocketdyne Division of Rockwell International , Inc. Teledyne CAE...actions exerted by individual components on the gas flow must be known. These specific component effects are distributed internally within the

Sloshing response of a reactor tank with internals

NASA Astrophysics Data System (ADS)

Ma, D. C.; Gvildys, J.; Chang, Y. W.

The sloshing response of a large reactor tank with in tank components is presented. It is indicated that the presence of the internal components can significantly change the dynamic characteristics of the sloshing motion. The sloshing frequency of a tank with internals is considerably higher than that of a tank without internal. The higher sloshing frequency reduces the sloshing wave height on the free surface but increases the dynamic pressure in the fluid.

The Social Value of Knowledge and the Responsiveness Requirement for International Research.

PubMed

Wenner, Danielle M

2017-02-01

Ethicists have long recognized that two necessary features of ethical research are scientific validity and social value. Yet despite a significant literature surrounding the validity component of this dictate, until recently there has been little attention paid to unpacking what the social value component might require. This article introduces a framework for assessing the social value of research, and in particular, for determining whether a given research program is likely to have significant social value of the kind necessary to fulfill the social value requirement. The article goes on to illustrate how this framework can provide a clearer account of the responsiveness requirement, an ethical dictum that is oft-repeated but whose content and value as a guideline in international research remains contested. Although I introduce this conception of social value in the context of the responsiveness requirement, the account offered can, and is intended to, stand alone as a tool for the assessment of the social value of research. As such it can be usefully applied to discussions about the value of comparative effectiveness trials, the assessment of the continued proliferation of me-too drugs and the research done to develop them, the demand for public access to study-generated data, and persistent deficits in the publication of negative results. © 2017 John Wiley & Sons Ltd.

75 FR 41889 - In the Matter of Certain Collaborative System Products and Components Thereof (II); Notice of...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-19

... INTERNATIONAL TRADE COMMISSION [Inv. No. 337-TA-728] In the Matter of Certain Collaborative System Products and Components Thereof (II); Notice of Investigation AGENCY: U.S. International Trade Commission... complaint was filed with the U.S. International Trade Commission on June 15, 2010, under section 337 of the...

The role of internal waves in larval fish interactions with potential predators and prey

NASA Astrophysics Data System (ADS)

Greer, Adam T.; Cowen, Robert K.; Guigand, Cedric M.; Hare, Jonathan A.; Tang, Dorothy

2014-09-01

Tidally driven internal wave packets in coastal environments have the potential to influence patchiness of larval fishes, prey, and gelatinous predators. We used the In Situ Ichthyoplankton Imaging System (ISIIS) to synoptically sample larval fishes, copepods, and planktonic predators (ctenophores, hydromedusae, chaetognaths, and polychaetes) across these predictable features in the summer near Stellwagen Bank, Massachusetts, USA. Full water column profiles and fixed depth transects (∼10 m depth) were used to quantify vertical and horizontal components of the fish and invertebrate distributions during stable and vertically mixed conditions associated with tidally generated internal waves. Larval fishes, consisting mostly of Urophycis spp., Merluccius bilinearis, and Labridae, were concentrated near the surface, with larger sizes generally occupying greater depths. During stable water column conditions, copepods formed a near surface thin layer several meters above the chlorophyll-a maximum that was absent when internal waves were propagating. In contrast, ctenophores and other predators were much more abundant at depth, but concentrations near 10 m increased immediately after the internal hydraulic jump mixed the water column. During the propagation of internal waves, the fine-scale abundance of larval fishes was more correlated with the abundance of gelatinous predators and less correlated with copepods compared to the stable conditions. Vertical oscillations caused by the internal hydraulic jump can disperse patches of zooplankton and force surface dwelling larval fishes into deeper water where probability of predator contact is increased, creating conditions potentially less favorable for larval fish growth and survival on short time scales.

Method of operating a thermoelectric generator

DOEpatents

Reynolds, Michael G; Cowgill, Joshua D

2013-11-05

A method for operating a thermoelectric generator supplying a variable-load component includes commanding the variable-load component to operate at a first output and determining a first load current and a first load voltage to the variable-load component while operating at the commanded first output. The method also includes commanding the variable-load component to operate at a second output and determining a second load current and a second load voltage to the variable-load component while operating at the commanded second output. The method includes calculating a maximum power output of the thermoelectric generator from the determined first load current and voltage and the determined second load current and voltage, and commanding the variable-load component to operate at a third output. The commanded third output is configured to draw the calculated maximum power output from the thermoelectric generator.

The making of an instrument: from concept to market.

PubMed

Christoudias, G C

1998-01-01

This is an account of the steps one goes through in the development of a new device or instrument. It starts with the conditions that generate the need and then the concept of a new instrument and goes through the process of designing it and protecting it with a patent; it then proceeds through the development of a working prototype and a final refined product. It provides an outline of the steps needed to get the device into the national or international market by selling or licensing it to a company willing to develop it. To be able to demonstrate this process of invention and give real life to the steps involved in the making of an instrument as mentioned above, I describe the circumstances that generated the idea and the development of the Christoudias Tissue Approximator Grasper. The patent is published as issued to demonstrate its different components.

Hybrid Correlation Energy (HyCE): An Approach Based on Separate Evaluations of Internal and External Components.

PubMed

Ivanic, Joseph; Schmidt, Michael W

2018-06-04

A novel hybrid correlation energy (HyCE) approach is proposed that determines the total correlation energy via distinct computation of its internal and external components. This approach evolved from two related studies. First, rigorous assessment of the accuracies and size extensivities of a number of electron correlation methods, that include perturbation theory (PT2), coupled-cluster (CC), configuration interaction (CI), and coupled electron pair approximation (CEPA), shows that the CEPA(0) variant of the latter and triples-corrected CC methods consistently perform very similarly. These findings were obtained by comparison to near full CI results for four small molecules and by charting recovered correlation energies for six steadily growing chain systems. Second, by generating valence virtual orbitals (VVOs) and utilizing the CEPA(0) method, we were able to partition total correlation energies into internal (or nondynamic) and external (or dynamic) parts for the aforementioned six chain systems and a benchmark test bed of 36 molecules. When using triple-ζ basis sets it was found that per orbital internal correlation energies were appreciably larger than per orbital external energies and that the former showed far more chemical variation than the latter. Additionally, accumulations of external correlation energies were seen to proceed smoothly, and somewhat linearly, as the virtual space is gradually increased. Combination of these two studies led to development of the HyCE approach, whereby the internal and external correlation energies are determined separately by CEPA(0)/VVO and PT2/external calculations, respectively. When applied to the six chain systems and the 36-molecule benchmark test set it was found that HyCE energies followed closely those of triples-corrected CC and CEPA(0) while easily outperforming MP2 and CCSD. The success of the HyCE approach is more notable when considering that its cost is only slightly more than MP2 and significantly cheaper than the CC approaches.

26 CFR 26.6081-1 - Automatic extension of time for filing generation-skipping transfer tax returns.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 26 Internal Revenue 14 2011-04-01 2010-04-01 true Automatic extension of time for filing generation-skipping transfer tax returns. 26.6081-1 Section 26.6081-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) ESTATE AND GIFT TAXES GENERATION-SKIPPING TRANSFER TAX...

26 CFR 26.6081-1 - Automatic extension of time for filing generation-skipping transfer tax returns.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 26 Internal Revenue 14 2010-04-01 2010-04-01 false Automatic extension of time for filing generation-skipping transfer tax returns. 26.6081-1 Section 26.6081-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) ESTATE AND GIFT TAXES GENERATION-SKIPPING TRANSFER TAX...

26 CFR 26.6081-1 - Automatic extension of time for filing generation-skipping transfer tax returns.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 26 Internal Revenue 14 2013-04-01 2013-04-01 false Automatic extension of time for filing generation-skipping transfer tax returns. 26.6081-1 Section 26.6081-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) ESTATE AND GIFT TAXES GENERATION-SKIPPING TRANSFER TAX...

26 CFR 26.6081-1 - Automatic extension of time for filing generation-skipping transfer tax returns.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 26 Internal Revenue 14 2014-04-01 2013-04-01 true Automatic extension of time for filing generation-skipping transfer tax returns. 26.6081-1 Section 26.6081-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) ESTATE AND GIFT TAXES GENERATION-SKIPPING TRANSFER TAX...

26 CFR 26.6081-1 - Automatic extension of time for filing generation-skipping transfer tax returns.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 26 Internal Revenue 14 2012-04-01 2012-04-01 false Automatic extension of time for filing generation-skipping transfer tax returns. 26.6081-1 Section 26.6081-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) ESTATE AND GIFT TAXES GENERATION-SKIPPING TRANSFER TAX...

Effects of thermal and moisture cycling on the internal structure of stitched RTM laminates

NASA Technical Reports Server (NTRS)

Walker, Jeff; Roundy, Lance; Goering, Jon

1993-01-01

Conventional aerospace composites are strong and stiff in the directions parallel to the carbon fibers, but they are prone to delaminations and damage in the through-the-thickness directions. Recent research has shown that substantial improvements in damage tolerance are obtained from textile composites with Z-direction reinforcement provided by stitching, weaving, or braiding. Because of the mismatch in thermal and moisture expansion properties of the various material components, there is a potential for microcracks to develop in the resin matrix. These cracks can form to relieve the mechanical stresses that are generated during curing or in-service temperature cycles.

Functional Performance of an Enabling Atmosphere Revitalization Subsystem Architecture for Deep Space Exploration Missions

NASA Technical Reports Server (NTRS)

Perry, Jay L.; Abney, Morgan B.; Frederick, Kenneth R.; Greenwood, Zachary W.; Kayatin, Matthew J.; Newton, Robert L.; Parrish, Keith J.; Roman, Monsi C.; Takada, Kevin C.; Miller, Lee A.;

Comparison of implant component fractures in external and internal type: A 12-year retrospective study.

PubMed

Yi, Yuseung; Koak, Jai-Young; Kim, Seong-Kyun; Lee, Shin-Jae; Heo, Seong-Joo

2018-04-01

The aim of this study was to compare the fracture of implant component behavior of external and internal type of implants to suggest directions for successful implant treatment. Data were collected from the clinical records of all patients who received WARANTEC implants at Seoul National University Dental Hospital from February 2002 to January 2014 for 12 years. Total number of implants was 1,289 and an average of 3.2 implants was installed per patient. Information about abutment connection type, implant locations, platform sizes was collected with presence of implant component fractures and their managements. SPSS statistics software (version 24.0, IBM) was used for the statistical analysis. Overall fracture was significantly more frequent in internal type. The most frequently fractured component was abutment in internal type implants, and screw fracture occurred most frequently in external type. Analyzing by fractured components, screw fracture was the most frequent in the maxillary anterior region and the most abutment fracture occurred in the maxillary posterior region and screw fractures occurred more frequently in NP (narrow platform) and abutment fractures occurred more frequently in RP (regular platform). In external type, screw fracture occurred most frequently, especially in the maxillary anterior region, and in internal type, abutment fracture occurred frequently in the posterior region. placement of an external type implant rather than an internal type is recommended for the posterior region where abutment fractures frequently occur.

A Study on Components of Internal Control-Based Administrative System in Secondary Schools

ERIC Educational Resources Information Center

Montri, Paitoon; Sirisuth, Chaiyuth; Lammana, Preeda

2015-01-01

The aim of this study was to study the components of the internal control-based administrative system in secondary schools, and make a Confirmatory Factor Analysis (CFA) to confirm the goodness of fit of empirical data and component model that resulted from the CFA. The study consisted of three steps: 1) studying of principles, ideas, and theories…

Looking for ideas: Eye behavior during goal-directed internally focused cognition☆

PubMed Central

Walcher, Sonja; Körner, Christof; Benedek, Mathias

2017-01-01

Humans have a highly developed visual system, yet we spend a high proportion of our time awake ignoring the visual world and attending to our own thoughts. The present study examined eye movement characteristics of goal-directed internally focused cognition. Deliberate internally focused cognition was induced by an idea generation task. A letter-by-letter reading task served as external task. Idea generation (vs. reading) was associated with more and longer blinks and fewer microsaccades indicating an attenuation of visual input. Idea generation was further associated with more and shorter fixations, more saccades and saccades with higher amplitudes as well as heightened stimulus-independent variation of eye vergence. The latter results suggest a coupling of eye behavior to internally generated information and associated cognitive processes, i.e. searching for ideas. Our results support eye behavior patterns as indicators of goal-directed internally focused cognition through mechanisms of attenuation of visual input and coupling of eye behavior to internally generated information. PMID:28689088

Field research internships: Why they impact students' decisions to major in the geosciences

NASA Astrophysics Data System (ADS)

Kortz, K. M.; Cardace, D.; Savage, B.; Rieger, D.

2017-12-01

Although internships have been shown to retain geoscience students, little research has been done on what components of research or field experiences during an internship impact students' decisions to major in the geosciences. We created and led a short, two-week field-based internship for 5 introductory-level students to conduct research and create a poster to present their results. In addition to the two professors leading the internship and the 5 interns, there were 2 masters students and 1 community college student who were returning to the field area to collect data for their own projects. These students also helped to guide and mentor the interns. The interns were diverse in many aspects: 3 were female, 2 were non-white, 3 were community college students (1 4YC student was a transfer), 2 were first-generation college students, and their ages ranged from 18 to 33. Based on our evaluation, we found that the research experience increased students' self-efficacy in the geosciences through various means, increased their connection with mentors and other individuals who could serve as resources, gave them a sense of belonging to the geoscience culture, increased their knowledge of geoscience career paths and expectations, helped them make connections with Earth, and maintained their interest. These factors have been described in the literature as leading to retention, and we propose that field-based internships are successful for recruitment or retention in the geosciences because they influence so many of these affective and cognitive components at once. In particular, the social aspect of internships plays a fundamental role in their success because many of these factors require close and sustained interactions with other people. An implication of this research is that these affective components, including social ones, should be explicitly considered in the design and implementation of internships to best serve as a recruitment and retention strategy.

Internal Motion Estimation by Internal-external Motion Modeling for Lung Cancer Radiotherapy.

PubMed

Chen, Haibin; Zhong, Zichun; Yang, Yiwei; Chen, Jiawei; Zhou, Linghong; Zhen, Xin; Gu, Xuejun

2018-02-27

The aim of this study is to develop an internal-external correlation model for internal motion estimation for lung cancer radiotherapy. Deformation vector fields that characterize the internal-external motion are obtained by respectively registering the internal organ meshes and external surface meshes from the 4DCT images via a recently developed local topology preserved non-rigid point matching algorithm. A composite matrix is constructed by combing the estimated internal phasic DVFs with external phasic and directional DVFs. Principle component analysis is then applied to the composite matrix to extract principal motion characteristics, and generate model parameters to correlate the internal-external motion. The proposed model is evaluated on a 4D NURBS-based cardiac-torso (NCAT) synthetic phantom and 4DCT images from five lung cancer patients. For tumor tracking, the center of mass errors of the tracked tumor are 0.8(±0.5)mm/0.8(±0.4)mm for synthetic data, and 1.3(±1.0)mm/1.2(±1.2)mm for patient data in the intra-fraction/inter-fraction tracking, respectively. For lung tracking, the percent errors of the tracked contours are 0.06(±0.02)/0.07(±0.03) for synthetic data, and 0.06(±0.02)/0.06(±0.02) for patient data in the intra-fraction/inter-fraction tracking, respectively. The extensive validations have demonstrated the effectiveness and reliability of the proposed model in motion tracking for both the tumor and the lung in lung cancer radiotherapy.

Exact and near backscattering measurements of the linear depolarisation ratio of various ice crystal habits generated in a laboratory cloud chamber

NASA Astrophysics Data System (ADS)

Smith, Helen R.; Connolly, Paul J.; Webb, Ann R.; Baran, Anthony J.

2016-07-01

Ice clouds were generated in the Manchester Ice Cloud Chamber (MICC), and the backscattering linear depolarisation ratio, δ, was measured for a variety of habits. To create an assortment of particle morphologies, the humidity in the chamber was varied throughout each experiment, resulting in a range of habits from the pristine to the complex. This technique was repeated at three temperatures: -7 °C, -15 °C and -30 °C, in order to produce both solid and hollow columns, plates, sectored plates and dendrites. A linearly polarised 532 nm continuous wave diode laser was directed through a section of the cloud using a non-polarising 50:50 beam splitter. Measurements of the scattered light were taken at 178°, 179° and 180°, using a Glan-Taylor prism to separate the co- and cross-polarised components. The intensities of these components were measured using two amplified photodetectors and the ratio of the cross- to co-polarised intensities was measured to find the linear depolarisation ratio. In general, it was found that Ray Tracing over-predicts the linear depolarisation ratio. However, by creating more accurate particle models which better represent the internal structure of ice particles, discrepancies between measured and modelled results (based on Ray Tracing) were reduced.

Performance characterization of a permanent-magnet helicon plasma thruster

NASA Astrophysics Data System (ADS)

Takahashi, Kazunori; Charles, Christine; Boswell, Rod

2012-10-01

Helicon plasma thrusters operated at a few kWs of rf power is an active area of an international research. Recent experiments have clarified part of the thrust-generation mechanisms. Thrust components which have been identified include an electron pressure inside the source region and a Lorentz force due to an electron diamagnetic drift current and a radial component of the applied magnetic field. The use of permanent magnets (PMs) instead of solenoids is one of the solutions for improving the thruster efficiency because it does not require electricity for the magnetic nozzle formation. Here the thrust imparted from a permanent-magnet helicon plasma thruster is directly measured using a pendulum thrust balance. The source consists of permanent magnet (PM) arrays, a double turn rf loop antenna powered by a 13.56 MHz rf generator and a glass source tube. The PM arrays provide a magnetic nozzle near the open exit of the source and two configurations, which have maximum field strengths of about 100 and 270 G, are tested. A thrust of 15 mN, specific impulse of 2000 sec and a thrust efficiency of 8 percent are presently obtained for 2 kW of input power, 24 sccm flow rate of argon and the stronger magnetic field configuration.

Simulation of vehicle acoustics in support of netted sensor research and development

NASA Astrophysics Data System (ADS)

Christou, Carol T.; Jacyna, Garry M.

2005-05-01

The MITRE Corporation has initiated a three-year internally-funded research program in netted sensors, the first-year effort focusing on vehicle detection for border monitoring. An important component is developing an understanding of the complex acoustic structure of vehicle noise to aid in netted sensor-based detection and classification. This presentation will discuss the design of a high-fidelity vehicle acoustic simulator to model the generation and transmission of acoustic energy from a moving vehicle to a collection of sensor nodes. Realistic spatially-dependent automobile sounds are generated from models of the engine cylinder firing rates, muffler and manifold resonances, and speed-dependent tire whine noise. Tire noise is the dominant noise source for vehicle speeds in excess of 30 miles per hour (MPH). As a result, we have developed detailed models that successfully predict the tire noise spectrum as a function of speed, road surface wave-number spectrum, tire geometry, and tire tread pattern. We have also included realistic descriptions of the spatial directivity patterns for the engine harmonics, muffler, and tire whine noise components. The acoustic waveforms are propagated to each sensor node using a simple phase-dispersive multi-path model. A brief description of the models and their corresponding outputs is provided.

A deep dynamo generating Mercury's magnetic field.

PubMed

Christensen, Ulrich R

2006-12-21

Mercury has a global magnetic field of internal origin and it is thought that a dynamo operating in the fluid part of Mercury's large iron core is the most probable cause. However, the low intensity of Mercury's magnetic field--about 1% the strength of the Earth's field--cannot be reconciled with an Earth-like dynamo. With the common assumption that Coriolis and Lorentz forces balance in planetary dynamos, a field thirty times stronger is expected. Here I present a numerical model of a dynamo driven by thermo-compositional convection associated with inner core solidification. The thermal gradient at the core-mantle boundary is subadiabatic, and hence the outer region of the liquid core is stably stratified with the dynamo operating only at depth, where a strong field is generated. Because of the planet's slow rotation the resulting magnetic field is dominated by small-scale components that fluctuate rapidly with time. The dynamo field diffuses through the stable conducting region, where rapidly varying parts are strongly attenuated by the skin effect, while the slowly varying dipole and quadrupole components pass to some degree. The model explains the observed structure and strength of Mercury's surface magnetic field and makes predictions that are testable with space missions both presently flying and planned.

Utilizing Radioisotope Power System Waste Heat for Spacecraft Thermal Management

NASA Technical Reports Server (NTRS)

Pantano, David R.; Dottore, Frank; Geng, Steven M.; Schrieber, Jeffrey G.; Tobery, E. Wayne; Palko, Joseph L.

2005-01-01

One of the advantages of using a Radioisotope Power System (RPS) for deep space or planetary surface missions is the readily available waste heat, which can be used to maintain electronic components within a controlled temperature range, to warm propulsion tanks and mobility actuators, and to gasify liquid propellants. Previous missions using Radioisotope Thermoelectric Generators (RTGs) dissipated a very large quantity of waste heat due to the relatively low efficiency of the thermoelectric conversion technology. The next generation RPSs, such as the 110-watt Stirling Radioisotope Generator (SRG110) will have much higher conversion efficiencies than their predecessors and therefore may require alternate approaches to transferring waste heat to the spacecraft. RTGs, with efficiencies of approx. 6 to 7% and 200 C housing surface temperatures, would need to use large and heavy radiator heat exchangers to transfer the waste heat to the internal spacecraft components. At the same time, sensitive spacecraft instruments must be shielded from the thermal radiation by using the heat exchangers or additional shields. The SRG110, with an efficiency around 22% and 50 C nominal housing surface temperature, can use the available waste heat more efficiently by more direct heat transfer methods such as heat pipes, thermal straps, or fluid loops. The lower temperatures allow the SRG110 much more flexibility to the spacecraft designers in configuring the generator without concern of overheating nearby scientific instruments, thereby eliminating the need for thermal shields. This paper will investigate using a high efficiency SRG110 for spacecraft thermal management and outline potential methods in several conceptual missions (Lunar Rover, Mars Rover, and Titan Lander) to illustrate the advantages with regard to ease of assembly, less complex interfaces, and overall mass savings.

Core-Noise Research

NASA Technical Reports Server (NTRS)

Hultgren, Lennart S.

2012-01-01

This presentation is a technical summary of and outlook for NASA-internal and NASA-sponsored external research on core noise funded by the Fundamental Aeronautics Program Subsonic Fixed Wing (SFW) Project. Sections of the presentation cover: the SFW system-level noise metrics for the 2015 (N+1), 2020 (N+2), and 2025 (N+3) timeframes; SFW strategic thrusts and technical challenges; SFW advanced subsystems that are broadly applicable to N+3 vehicle concepts, with an indication where further noise research is needed; the components of core noise (compressor, combustor and turbine noise) and a rationale for NASA's current emphasis on the combustor-noise component; the increase in the relative importance of core noise due to turbofan design trends; the need to understand and mitigate core-noise sources for high-efficiency small gas generators; and the current research activities in the core-noise area, with additional details given about forthcoming updates to NASA's Aircraft Noise Prediction Program (ANOPP) core-noise prediction capabilities, two NRA efforts (Honeywell International, Phoenix, AZ and University of Illinois at Urbana-Champaign, respectively) to improve the understanding of core-noise sources and noise propagation through the engine core, and an effort to develop oxide/oxide ceramic-matrix-composite (CMC) liners for broadband noise attenuation suitable for turbofan-core application. Core noise must be addressed to ensure that the N+3 noise goals are met. Focused, but long-term, core-noise research is carried out to enable the advanced high-efficiency small gas-generator subsystem, common to several N+3 conceptual designs, needed to meet NASA's technical challenges. Intermediate updates to prediction tools are implemented as the understanding of the source structure and engine-internal propagation effects is improved. The NASA Fundamental Aeronautics Program has the principal objective of overcoming today's national challenges in air transportation. The SFW Quiet-Aircraft Subproject aims to develop concepts and technologies to reduce perceived community noise attributable to aircraft with minimal impact on weight and performance. This reduction of aircraft noise is critical to enabling the anticipated large increase in future air traffic.

What humankind can expect with an inversion of Earth’s magnetic field: threats real and imagined

NASA Astrophysics Data System (ADS)

Tsareva, O. O.; Zelenyi, L. M.; Malova, H. V.; Podzolko, M. V.; Popova, E. P.; Popov, V. Yu

2018-02-01

Earth’s global magnetic field generated by an internal dynamo mechanism has been continuously changing on different time scales since its formation. Paleodata indicate that relatively long periods of evolutionary changes can be replaced by quick magnetic inversions. Based on observations, Earth’s magnetic field is currently weakening and the magnetic poles are shifting, possibly indicating the beginning of the inversion process. This paper invokes Gauss coefficients to approximate the behavior of Earth’s magnetic field components over the past 100 years. Using the extrapolation method, it is estimated that the magnetic dipole component will vanish by the year 3600 and at that time the geomagnetic field will be determined by a smaller value of a quadrupole magnetic component. A numerical model is constructed which allows evaluating and comparing both galactic and solar cosmic ray fluxes in Earth’s magnetosphere and on its surface during periods of dipole or quadrupole domination. The role of the atmosphere in absorbing particles of cosmic rays is taken into account. An estimate of the radiation danger to humans is obtained for the ground level and for the International Space Station altitude of ∼ 400 km. It is shown that in the most unfavorable, minimum field interval of the inversion process, the galactic cosmic ray flux increases by no more than a factor of three, implying that the radiation danger does not exceed the maximum permissible dose. Thus, the danger of magnetic inversion periods generally should not have fatal consequences for humans and nature as a whole, despite dramatically changing the structure of Earth’s magnetosphere.

The impact of sedimentary anisotropy on solute mixing in stacked scour-pool structures

NASA Astrophysics Data System (ADS)

Bennett, Jeremy P.; Haslauer, Claus P.; Cirpka, Olaf A.

2017-04-01

The spatial variability of hydraulic conductivity is known to have a strong impact on solute spreading and mixing. In most investigations, its local anisotropy has been neglected. Recent studies have shown that spatially varying orientation in sedimentary anisotropy can lead to twisting flow enhancing transverse mixing, but most of these studies used geologically implausible geometries. We use an object-based approach to generate stacked scour-pool structures with either isotropic or anisotropic filling which are typically reported in glacial outwash deposits. We analyze how spatially variable isotropic conductivity and variation of internal anisotropy in these features impacts transverse plume deformation and both longitudinal and transverse spreading and mixing. In five test cases, either the scalar values of conductivity or the spatial orientation of its anisotropy is varied between the scour-pool structures. Based on 100 random configurations, we compare the variability of velocity components, stretching and folding metrics, advective travel-time distributions, one and two-particle statistics in advective-dispersive transport, and the flux-related dilution indices for steady state advective-dispersive transport among the five test cases. Variation in the orientation of internal anisotropy causes strong variability in the lateral velocity components, which leads to deformation in transverse directions and enhances transverse mixing, whereas it hardly affects the variability of the longitudinal velocity component and thus longitudinal spreading and mixing. The latter is controlled by the spatial variability in the scalar values of hydraulic conductivity. Our results demonstrate that sedimentary anisotropy is important for transverse mixing, whereas it may be neglected when considering longitudinal spreading and mixing.

Improvement of early detection of breast cancer through collaborative multi-country efforts: Medical physics component.

PubMed

Mora, Patricia; Faulkner, Keith; Mahmoud, Ahmed M; Gershan, Vesna; Kausik, Aruna; Zdesar, Urban; Brandan, María-Ester; Kurt, Serap; Davidović, Jasna; Salama, Dina H; Aribal, Erkin; Odio, Clara; Chaturvedi, Arvind K; Sabih, Zahida; Vujnović, Saša; Paez, Diana; Delis, Harry

2018-04-01

The International Atomic Energy Agency (IAEA) through a Coordinated Research Project on "Enhancing Capacity for Early Detection and Diagnosis of Breast Cancer through Imaging", brought together a group of mammography radiologists, medical physicists and radiographers; to investigate current practices and improve procedures for the early detection of breast cancer by strengthening both the clinical and medical physics components. This paper addresses the medical physics component. The countries that participated in the CRP were Bosnia and Herzegovina, Costa Rica, Egypt, India, Kenya, the Frmr. Yug. Rep. of Macedonia, Mexico, Nigeria, Pakistan, Philippines, Slovenia, Turkey, Uganda, United Kingdom and Zambia. Ten institutions participated using IAEA quality control protocols in 9 digital and 3 analogue mammography equipment. A spreadsheet for data collection was generated and distributed. Evaluation of image quality was done using TOR MAX and DMAM2 Gold phantoms. QC results for analogue equipment showed satisfactory results. QC tests performed on digital systems showed that improvements needed to be implemented, especially in thickness accuracy, signal difference to noise ratio (SDNR) values for achievable levels, uniformity and modulation transfer function (MTF). Mean glandular dose (MGD) was below international recommended levels for patient radiation protection. Evaluation of image quality by phantoms also indicated the need for improvement. Common activities facilitated improvement in mammography practice, including training of medical physicists in QC programs and infrastructure was improved and strengthened; networking among medical physicists and radiologists took place and was maintained over time. IAEA QC protocols provided a uniformed approach to QC measurements. Copyright © 2018 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

Thermal Analysis of Fermilab Mu2e Beamstop and Structural Analysis of Beamline Components

DOE Office of Scientific and Technical Information (OSTI.GOV)

Narug, Colin S.

The Mu2e project at Fermilab National Accelerator Laboratory aims to observe the unique conversion of muons to electrons. The success or failure of the experiment to observe this conversion will further the understanding of the standard model of physics. Using the particle accelerator, protons will be accelerated and sent to the Mu2e experiment, which will separate the muons from the beam. The muons will then be observed to determine their momentum and the particle interactions occur. At the end of the Detector Solenoid, the internal components will need to absorb the remaining particles of the experiment using polymer absorbers. Becausemore » the internal structure of the beamline is in a vacuum, the heat transfer mechanisms that can disperse the energy generated by the particle absorption is limited to conduction and radiation. To determine the extent that the absorbers will heat up over one year of operation, a transient thermal finite element analysis has been performed on the Muon Beam Stop. The levels of energy absorption were adjusted to determine the thermal limit for the current design. Structural finite element analysis has also been performed to determine the safety factors of the Axial Coupler, which connect and move segments of the beamline. The safety factor of the trunnion of the Instrument Feed Through Bulk Head has also been determined for when it is supporting the Muon Beam Stop. The results of the analysis further refine the design of the beamline components prior to testing, fabrication, and installation.« less

Infrared thermography non-destructive evaluation of lithium-ion battery

NASA Astrophysics Data System (ADS)

Wang, Zi-jun; Li, Zhi-qiang; Liu, Qiang

2011-08-01

The power lithium-ion battery with its high specific energy, high theoretical capacity and good cycle-life is a prime candidate as a power source for electric vehicles (EVs) and hybrid electric vehicles (HEVs). Safety is especially important for large-scale lithium-ion batteries, especially the thermal analysis is essential for their development and design. Thermal modeling is an effective way to understand the thermal behavior of the lithium-ion battery during charging and discharging. With the charging and discharging, the internal heat generation of the lithium-ion battery becomes large, and the temperature rises leading to an uneven temperature distribution induces partial degradation. Infrared (IR) Non-destructive Evaluation (NDE) has been well developed for decades years in materials, structures, and aircraft. Most thermographic methods need thermal excitation to the measurement structures. In NDE of battery, the thermal excitation is the heat generated from carbon and cobalt electrodes in electrolyte. A technique named "power function" has been developed to determine the heat by chemical reactions. In this paper, the simulations of the transient response of the temperature distribution in the lithium-ion battery are developed. The key to resolving the security problem lies in the thermal controlling, including the heat generation and the internal and external heat transfer. Therefore, three-dimensional modelling for capturing geometrical thermal effects on battery thermal abuse behaviour is required. The simulation model contains the heat generation during electrolyte decomposition and electrical resistance component. Oven tests are simulated by three-dimensional model and the discharge test preformed by test system. Infrared thermography of discharge is recorded in order to analyze the security of the lithium-ion power battery. Nondestructive detection is performed for thermal abuse analysis and discharge analysis.

Residual stress prediction in a powder bed fusion manufactured Ti6Al4V hip stem

NASA Astrophysics Data System (ADS)

Barrett, Richard A.; Etienne, Titouan; Duddy, Cormac; Harrison, Noel M.

2017-10-01

Powder bed fusion (PBF) is a category of additive manufacturing (AM) that is particularly suitable for the production of 3D metallic components. In PBF, only material in the current build layer is at the required melt temperature, with the previously melted and solidified layers reducing in temperature, thus generating a significant thermal gradient within the metallic component, particularly for laser based PBF components. The internal thermal stresses are subsequently relieved in a post-processing heat-treatment step. Failure to adequately remove these stresses can result in cracking and component failure. A prototype hip stem was manufactured from Ti6Al4V via laser PBF but was found to have fractured during over-seas shipping. This study examines the evolution of thermal stresses during the laser PBF manufacturing and heat treatment processes of the hip stem in a 2D finite element analysis (FEA) and compares it to an electron beam PBF process. A custom written script for the automatic conversion of a gross geometry finite element model into a thin layer- by-layer finite element model was developed. The build process, heat treatment (for laser PBF) and the subsequent cooling were simulated at the component level. The results demonstrate the effectiveness of the heat treatment in reducing PBF induced thermal stresses, and the concentration of stresses in the region that fractured.

Preserving Envelope Efficiency in Performance Based Code Compliance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thornton, Brian A.; Sullivan, Greg P.; Rosenberg, Michael I.

2015-06-20

The City of Seattle 2012 Energy Code (Seattle 2014), one of the most progressive in the country, is under revision for its 2015 edition. Additionally, city personnel participate in the development of the next generation of the Washington State Energy Code and the International Energy Code. Seattle has pledged carbon neutrality by 2050 including buildings, transportation and other sectors. The United States Department of Energy (DOE), through Pacific Northwest National Laboratory (PNNL) provided technical assistance to Seattle in order to understand the implications of one potential direction for its code development, limiting trade-offs of long-lived building envelope components less stringentmore » than the prescriptive code envelope requirements by using better-than-code but shorter-lived lighting and heating, ventilation, and air-conditioning (HVAC) components through the total building performance modeled energy compliance path. Weaker building envelopes can permanently limit building energy performance even as lighting and HVAC components are upgraded over time, because retrofitting the envelope is less likely and more expensive. Weaker building envelopes may also increase the required size, cost and complexity of HVAC systems and may adversely affect occupant comfort. This report presents the results of this technical assistance. The use of modeled energy code compliance to trade-off envelope components with shorter-lived building components is not unique to Seattle and the lessons and possible solutions described in this report have implications for other jurisdictions and energy codes.« less

A multi-dimensional functional principal components analysis of EEG data.

PubMed

Hasenstab, Kyle; Scheffler, Aaron; Telesca, Donatello; Sugar, Catherine A; Jeste, Shafali; DiStefano, Charlotte; Şentürk, Damla

2017-09-01

The electroencephalography (EEG) data created in event-related potential (ERP) experiments have a complex high-dimensional structure. Each stimulus presentation, or trial, generates an ERP waveform which is an instance of functional data. The experiments are made up of sequences of multiple trials, resulting in longitudinal functional data and moreover, responses are recorded at multiple electrodes on the scalp, adding an electrode dimension. Traditional EEG analyses involve multiple simplifications of this structure to increase the signal-to-noise ratio, effectively collapsing the functional and longitudinal components by identifying key features of the ERPs and averaging them across trials. Motivated by an implicit learning paradigm used in autism research in which the functional, longitudinal, and electrode components all have critical interpretations, we propose a multidimensional functional principal components analysis (MD-FPCA) technique which does not collapse any of the dimensions of the ERP data. The proposed decomposition is based on separation of the total variation into subject and subunit level variation which are further decomposed in a two-stage functional principal components analysis. The proposed methodology is shown to be useful for modeling longitudinal trends in the ERP functions, leading to novel insights into the learning patterns of children with Autism Spectrum Disorder (ASD) and their typically developing peers as well as comparisons between the two groups. Finite sample properties of MD-FPCA are further studied via extensive simulations. © 2017, The International Biometric Society.

Development of probabilistic internal dosimetry computer code

NASA Astrophysics Data System (ADS)

Noh, Siwan; Kwon, Tae-Eun; Lee, Jai-Ki

2017-02-01

Internal radiation dose assessment involves biokinetic models, the corresponding parameters, measured data, and many assumptions. Every component considered in the internal dose assessment has its own uncertainty, which is propagated in the intake activity and internal dose estimates. For research or scientific purposes, and for retrospective dose reconstruction for accident scenarios occurring in workplaces having a large quantity of unsealed radionuclides, such as nuclear power plants, nuclear fuel cycle facilities, and facilities in which nuclear medicine is practiced, a quantitative uncertainty assessment of the internal dose is often required. However, no calculation tools or computer codes that incorporate all the relevant processes and their corresponding uncertainties, i.e., from the measured data to the committed dose, are available. Thus, the objective of the present study is to develop an integrated probabilistic internal-dose-assessment computer code. First, the uncertainty components in internal dosimetry are identified, and quantitative uncertainty data are collected. Then, an uncertainty database is established for each component. In order to propagate these uncertainties in an internal dose assessment, a probabilistic internal-dose-assessment system that employs the Bayesian and Monte Carlo methods. Based on the developed system, we developed a probabilistic internal-dose-assessment code by using MATLAB so as to estimate the dose distributions from the measured data with uncertainty. Using the developed code, we calculated the internal dose distribution and statistical values ( e.g. the 2.5th, 5th, median, 95th, and 97.5th percentiles) for three sample scenarios. On the basis of the distributions, we performed a sensitivity analysis to determine the influence of each component on the resulting dose in order to identify the major component of the uncertainty in a bioassay. The results of this study can be applied to various situations. In cases of severe internal exposure, the causation probability of a deterministic health effect can be derived from the dose distribution, and a high statistical value ( e.g., the 95th percentile of the distribution) can be used to determine the appropriate intervention. The distribution-based sensitivity analysis can also be used to quantify the contribution of each factor to the dose uncertainty, which is essential information for reducing and optimizing the uncertainty in the internal dose assessment. Therefore, the present study can contribute to retrospective dose assessment for accidental internal exposure scenarios, as well as to internal dose monitoring optimization and uncertainty reduction.

Building energy analysis tool

DOEpatents

Brackney, Larry; Parker, Andrew; Long, Nicholas; Metzger, Ian; Dean, Jesse; Lisell, Lars

2016-04-12

A building energy analysis system includes a building component library configured to store a plurality of building components, a modeling tool configured to access the building component library and create a building model of a building under analysis using building spatial data and using selected building components of the plurality of building components stored in the building component library, a building analysis engine configured to operate the building model and generate a baseline energy model of the building under analysis and further configured to apply one or more energy conservation measures to the baseline energy model in order to generate one or more corresponding optimized energy models, and a recommendation tool configured to assess the one or more optimized energy models against the baseline energy model and generate recommendations for substitute building components or modifications.

Surface generation and editing operations applied to structural support of aerospace vehicle fuselages. M.S. Thesis

NASA Technical Reports Server (NTRS)

Schwartz, Susan K.

1992-01-01

The Solid Modeling Aerospace Research Tool (SMART) is a computer aided design tool used in aerospace vehicle design. Modeling of structural components using SMART includes the representation of the transverse or cross-wise elements of a vehicle's fuselage, ringframes, and bulkheads. Ringframes are placed along a vehicle's fuselage to provide structural support and maintain the shape of the fuselage. Bulkheads are also used to maintain shape, but are placed at locations where substantial structural support is required. Given a Bezier curve representation of a cross sectional cut through a vehicle's fuselage and/or an internal tank, this project produces a first-guess Bezier patch representation of a ringframe or bulkhead at the cross-sectional position. The grid produced is later used in the structural analysis of the vehicle. The graphical display of the generated patches allows the user to edit patch control points in real time. Constraints considered in the patch generation include maintaining 'square-like' patches and placement of longitudinal, or lengthwise along the fuselage, structural elements called longerons.

Aspects of body self-calibration

NASA Technical Reports Server (NTRS)

Lackner, J. R.; DiZio, P. A.

2000-01-01

The representation of body orientation and configuration is dependent on multiple sources of afferent and efferent information about ongoing and intended patterns of movement and posture. Under normal terrestrial conditions, we feel virtually weightless and we do not perceive the actual forces associated with movement and support of our body. It is during exposure to unusual forces and patterns of sensory feedback during locomotion that computations and mechanisms underlying the ongoing calibration of our body dimensions and movements are revealed. This review discusses the normal mechanisms of our position sense and calibration of our kinaesthetic, visual and auditory sensory systems, and then explores the adaptations that take place to transient Coriolis forces generated during passive body rotation. The latter are very rapid adaptations that allow body movements to become accurate again, even in the absence of visual feedback. Muscle spindle activity interpreted in relation to motor commands and internally modeled reafference is an important component in permitting this adaptation. During voluntary rotary movements of the body, the central nervous system automatically compensates for the Coriolis forces generated by limb movements. This allows accurate control to be maintained without our perceiving the forces generated.

Statistical Compression of Wind Speed Data

NASA Astrophysics Data System (ADS)

Tagle, F.; Castruccio, S.; Crippa, P.; Genton, M.

2017-12-01

In this work we introduce a lossy compression approach that utilizes a stochastic wind generator based on a non-Gaussian distribution to reproduce the internal climate variability of daily wind speed as represented by the CESM Large Ensemble over Saudi Arabia. Stochastic wind generators, and stochastic weather generators more generally, are statistical models that aim to match certain statistical properties of the data on which they are trained. They have been used extensively in applications ranging from agricultural models to climate impact studies. In this novel context, the parameters of the fitted model can be interpreted as encoding the information contained in the original uncompressed data. The statistical model is fit to only 3 of the 30 ensemble members and it adequately captures the variability of the ensemble in terms of seasonal internannual variability of daily wind speed. To deal with such a large spatial domain, it is partitioned into 9 region, and the model is fit independently to each of these. We further discuss a recent refinement of the model, which relaxes this assumption of regional independence, by introducing a large-scale component that interacts with the fine-scale regional effects.

Computer Software Configuration Item-Specific Flight Software Image Transfer Script Generator

NASA Technical Reports Server (NTRS)

Bolen, Kenny; Greenlaw, Ronald

2010-01-01

A K-shell UNIX script enables the International Space Station (ISS) Flight Control Team (FCT) operators in NASA s Mission Control Center (MCC) in Houston to transfer an entire or partial computer software configuration item (CSCI) from a flight software compact disk (CD) to the onboard Portable Computer System (PCS). The tool is designed to read the content stored on a flight software CD and generate individual CSCI transfer scripts that are capable of transferring the flight software content in a given subdirectory on the CD to the scratch directory on the PCS. The flight control team can then transfer the flight software from the PCS scratch directory to the Electronically Erasable Programmable Read Only Memory (EEPROM) of an ISS Multiplexer/ Demultiplexer (MDM) via the Indirect File Transfer capability. The individual CSCI scripts and the CSCI Specific Flight Software Image Transfer Script Generator (CFITSG), when executed a second time, will remove all components from their original execution. The tool will identify errors in the transfer process and create logs of the transferred software for the purposes of configuration management.

Student User Preferences for Features of Next-Generation OPACs: A Case Study of University of Sheffield International Students

ERIC Educational Resources Information Center

Tam, Winnie; Cox, Andrew M.; Bussey, Andy

2009-01-01

Purpose: The purpose of this paper is to identify the features that international student users prefer for next generation OPACs. Design/methodology/approach: A total of 16 international students of the University of Sheffield were interviewed in July 2008 to explore their preferences among potential features in next generation OPACs. A…

The Value of Science Policy Internships to Interns and Employers

NASA Astrophysics Data System (ADS)

Landau, E. A.

2014-12-01

My interns often look at me wide-eyed when I tell them to approach a Member of Congress at a congressional reception and introduce themselves. I understand their shock, as I once had the same experience. This presentation will look at the internship experience from the perspective of the intern and the employer, describing the value of the internship to each. I will detail my experience as an intern in the American Geosciences Institute Government Affairs Program, and my current position as the creator and hiring manager of the American Geophysical Union Public Affairs Department internship. This perspective will be augmented by information from recent AGU Public Affairs interns. Internships equate to experience, one critical and often underdeveloped component of a student or recent graduate's resume. Each of these internships offers the unique opportunity for students and recent graduates of geophysical science programs to immerse themselves in the science policy field, doing work alongside professionals and serving as an important part of their respective work environment. The networking opportunities and skills learned are highly valuable to those building their resumes and trying to break into the field - or simply figuring out what future career path to take. Scientific societies see value in investing in the next generation of scientific leaders and ensuring their perspective includes an understanding of science policy and the societal impacts of science. These internship experiences are often eye-opening and sometimes career-changing.

OCSEGen: Open Components and Systems Environment Generator

NASA Technical Reports Server (NTRS)

Tkachuk, Oksana

2014-01-01

To analyze a large system, one often needs to break it into smaller components.To analyze a component or unit under analysis, one needs to model its context of execution, called environment, which represents the components with which the unit interacts. Environment generation is a challenging problem, because the environment needs to be general enough to uncover unit errors, yet precise enough to make the analysis tractable. In this paper, we present a tool for automated environment generation for open components and systems. The tool, called OCSEGen, is implemented on top of the Soot framework. We present the tool's current support and discuss its possible future extensions.

Current Space Station Experiments Investigating Component Level Electronics Repair

NASA Technical Reports Server (NTRS)

Easton, John W.; Struk, Peter M.

2010-01-01

The Soldering in a Reduced Gravity Experiment (SoRGE) and Component Repair Experiment (CRE)-1 are tests performed on the International Space Station to determine the techniques, tools, and training necessary to allow future crews to perform manual electronics repairs at the component level. SoRGE provides information on the formation and internal structure of through-hole solder joints, illustrating the challenges and implications of soldering in reduced gravity. SoRGE showed a significant increase in internal void defects for joints formed in low gravity compared to normal gravity. Methods for mitigating these void defects were evaluated using a modified soldering process. CRE-1 demonstrated the removal, cleaning, and replacement of electronics components by manual means on functional circuit boards. The majority of components successful passed a post-repair functional test demonstrating the feasibility of component-level repair within the confines of a spacecraft. Together, these tasks provide information to recommend material and tool improvements, training improvements, and future work to help enable electronics repairs in future space missions.

78 FR 12354 - Certain Wireless Consumer Electronics Devices and Components Thereof; Commission Determination...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-22

... INTERNATIONAL TRADE COMMISSION [Investigation No. 337-TA-853] Certain Wireless Consumer Electronics Devices and Components Thereof; Commission Determination Concerning an Initial Determination Granting a Motion To Amend Complaint and Notice of Investigation AGENCY: U.S. International Trade...

Learning about the World.

ERIC Educational Resources Information Center

Lazer, Stephen

As a step toward acquiring international measures of geographic competence of students, an optional geography component was included in the second International Assessment of Educational Progress. Nine of the 20 countries participating in the assessment included the geography component, including 8 provinces. In each country a representative…

Internal trip capture estimator for mixed-use developments.

DOT National Transportation Integrated Search

2007-12-01

This report describes a spreadsheet tool for estimating trip generation for mixed-use developments, : accounting for internal trip capture. Internal trip capture is the portion of trips generated by a mixed-use : development that both begin and end w...

Generation and Evolution of Internal Waves in Luzon Strait

DTIC Science & Technology

2016-03-01

1 DISTRIBUTION STATEMENT A: Distribution approved for public release; distribution is unlimited. Generation and Evolution of Internal Waves in...internal tides, inertial waves , nonlinear internal waves (NLIWs), and turbulence mixing––in the ocean and thereby help develop improved parameterizations of...mixing for ocean models. Mixing within the stratified ocean is a particular focus as the complex interplay of internal waves from a variety of

Electrolyzer assembly method and system

DOEpatents

Swala, Dana Ray; Bourgeois, Richard Scott; Paraszczak, Steven; Buckley, Donald Joseph

2017-05-23

The present techniques provide a novel electrolyzer and methods for welding components of such electrolyzers. The techniques may use conductors, such as resistance wires, placed in paths around the internal structural features and edges of the components. The conductors may be incorporated into the components during manufacture by injection molding, or other molding techniques, or may be tacked or otherwise applied to the surface of the components after manufacture. When current, a field or other excitation is applied to the conductors, the plastic surrounding the wire is melted. If this plastic is in direct contact with an adjoining component, a strong, hermetic seal may be formed between the two components, including the internal structural features.

Utilizing Radioisotope Power System Waste Heat for Spacecraft Thermal Management

NASA Technical Reports Server (NTRS)

Pantano, David R.; Dottore, Frank; Tobery, E. Wayne; Geng, Steven M.; Schreiber, Jeffrey G.; Palko, Joseph L.

2005-01-01

An advantage of using a Radioisotope Power System (RPS) for deep space or planetary surface missions is the readily available waste heat, which can be used for a number of beneficial purposes including: maintaining electronic components within a controlled temperature range, warming propulsion tanks and mobility actuators, and maintaining liquid propellants above their freezing temperature. Previous missions using Radioisotope Thermoelectric Generators (RTGs) dissipated large quantities of waste heat due to the low efficiency of the thermoelectric conversion technology. The next generation RPSs, such as the 110-Watt Stirling Radioisotope Generator (SRG110) will have higher conversion efficiencies, thereby rejecting less waste heat at a lower temperature and may require alternate approaches to transferring waste heat to the spacecraft. RTGs, with efficiencies of 6 to 7 percent, reject their waste heat at the relatively high heat rejection temperature of 200 C. This is an advantage when rejecting heat to space; however, transferring heat to the internal spacecraft components requires a large and heavy radiator heat exchanger. At the same time, sensitive spacecraft instruments must be shielded from the thermal radiation of the RTG. The SRG110, with an efficiency around 22 percent and 50 C nominal housing surface temperature, can readily transfer the available waste heat directly via heat pipes, thermal straps, or fluid loops. The lower temperatures associated with the SRG110 avoid the chances of overheating other scientific components, eliminating the need for thermal shields. This provides the spacecraft designers more flexibility when locating the generator for a specific mission. A common misconception with high-efficiency systems is that there is not enough waste heat for spacecraft thermal management. This paper will dispel this misconception and investigate the use of a high-efficiency SRG110 for spacecraft thermal management and outline potential methods of waste heat utilization in several conceptual missions (Lunar Rover, Mars Rover, and Titan Lander). The advantages associated with the SRG110 as they relate to ease of assembly, less complex interfaces, and overall mass savings for a spacecraft will be highlighted.

Constitutional dynamic chemistry: bridge from supramolecular chemistry to adaptive chemistry.

PubMed

Lehn, Jean-Marie

2012-01-01

Supramolecular chemistry aims at implementing highly complex chemical systems from molecular components held together by non-covalent intermolecular forces and effecting molecular recognition, catalysis and transport processes. A further step consists in the investigation of chemical systems undergoing self-organization, i.e. systems capable of spontaneously generating well-defined functional supramolecular architectures by self-assembly from their components, thus behaving as programmed chemical systems. Supramolecular chemistry is intrinsically a dynamic chemistry in view of the lability of the interactions connecting the molecular components of a supramolecular entity and the resulting ability of supramolecular species to exchange their constituents. The same holds for molecular chemistry when the molecular entity contains covalent bonds that may form and break reversibility, so as to allow a continuous change in constitution by reorganization and exchange of building blocks. These features define a Constitutional Dynamic Chemistry (CDC) on both the molecular and supramolecular levels.CDC introduces a paradigm shift with respect to constitutionally static chemistry. The latter relies on design for the generation of a target entity, whereas CDC takes advantage of dynamic diversity to allow variation and selection. The implementation of selection in chemistry introduces a fundamental change in outlook. Whereas self-organization by design strives to achieve full control over the output molecular or supramolecular entity by explicit programming, self-organization with selection operates on dynamic constitutional diversity in response to either internal or external factors to achieve adaptation.The merging of the features: -information and programmability, -dynamics and reversibility, -constitution and structural diversity, points to the emergence of adaptive and evolutive chemistry, towards a chemistry of complex matter.

International Laser Ranging Services (ILRS) 2001 Annual Report

NASA Technical Reports Server (NTRS)

Pearlman, Michael (Editor); Torrence, Mark (Editor); Noll, Carey (Editor)

2002-01-01

This 2001 Annual Report of the International Laser Ranging Services (ILRS) is comprised of individual contributions from ILRS components within the international geodetic community. This report documents the work of the ILRS components for the year 2001. The report documents changes and progress of the ILRS. This document is also available on the ILRS Web site at http://ilrs.gsfc.nasa.gov/reports/ilrs_reports/ilrsar_2001.html.

Study on the measures to promote the use of photovoltaic power generating system overseas

NASA Astrophysics Data System (ADS)

1989-03-01

In order to understand the state of the utilizing photovoltaic power generating system, the present situation to promote its development, the actual status of the assistance for developing countries by each country or by each international organization, research was done for USA, principal western countries, UN and EC. First, development conditions of the solar cell utilizing technique were classified by each country at the standpoint of developing and promoting systems. Second, the projects and policies in each country or international organization were arranged to promote research, development and introduction. Next, the present situation of the photovoltaic power generation projects by civilian parties and the problems to assist the projects by each country were arranged. While, the present sutuation of the photovoltaic power generation projects assisted by the governments and international organizations were classified by each country and each international organizations. Finally, in view of importance in the photovoltaic power generation project, it was concluded that not only developed country governments and international organizations but also private enterprises in developed countries were required to expand the understanding about the photovoltaic power generation system.

Characteristics of Innovation in K12 International Schools in Asia

ERIC Educational Resources Information Center

Hale, Jessica A.

2017-01-01

This qualitative phenomenological study explored identifying characteristics and necessary components of educational innovation in K12 international schools in Asia. Two research questions guided the exploration of observed characteristics of innovation and global leader's perceptions of components of innovation. The findings suggested observed…

Three-dimensional analysis of magnetometer array data

NASA Technical Reports Server (NTRS)

Richmond, A. D.; Baumjohann, W.

1984-01-01

A technique is developed for mapping magnetic variation fields in three dimensions using data from an array of magnetometers, based on the theory of optimal linear estimation. The technique is applied to data from the Scandinavian Magnetometer Array. Estimates of the spatial power spectra for the internal and external magnetic variations are derived, which in turn provide estimates of the spatial autocorrelation functions of the three magnetic variation components. Statistical errors involved in mapping the external and internal fields are quantified and displayed over the mapping region. Examples of field mapping and of separation into external and internal components are presented. A comparison between the three-dimensional field separation and a two-dimensional separation from a single chain of stations shows that significant differences can arise in the inferred internal component.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Elliott, Stephen J.; Ni, Guangjian

The pressure distribution in each of the fluid chambers of the cochlea can be decomposed into a 1D, or plane wave, component and a near field component, which decays rapidly away from the excitation point. The transverse motion of the basilar membrane, BM, for example, generates both a 1D pressure field, which couples into the slow wave, and a local near field pressure, proportional to the BM acceleration, that generates an added mass on the BM due to the fluid motion. When the organ of Corti, OC, undergoes internal motion, due for example to outer hair cell activity, this motionmore » will not itself generate any 1D pressure if the OC is incompressible and the BM is constrained not to move volumetrically, and so will not directly couple into the slow wave. This motion will, however, generate a near field pressure, proportional to the OC acceleration, which will act on the OC and thus increases its effective mass. The near field pressure due to this OC motion will also act on the BM, generating a force on the BM proportional to the acceleration of the OC, and thus create a “coupling mass” effect. By reciprocity, this coupling mass is the same as that acting on the OC due to the motion of the BM. This near field fluid coupling is initially observed in a finite element model of a slice of the cochlea. These simulations suggest a simple analytical formulation for the fluid coupling, using higher order beam modes across the width of the cochlear partition. It is well known that the added mass due to the near field pressure dominates the overall mass of the BM, and thus significantly affects the micromechanical dynamics. This work not only quantifies the added mass of the OC due its own motion in the fluid, and shows that this is important, but also demonstrates that the coupling mass effect between the BM and OC significantly affects the dynamics of simple micromechanical models.« less

Developed-developing country partnerships: benefits to developed countries?

PubMed

Syed, Shamsuzzoha B; Dadwal, Viva; Rutter, Paul; Storr, Julie; Hightower, Joyce D; Gooden, Rachel; Carlet, Jean; Bagheri Nejad, Sepideh; Kelley, Edward T; Donaldson, Liam; Pittet, Didier

2012-06-18

Developing countries can generate effective solutions for today's global health challenges. This paper reviews relevant literature to construct the case for international cooperation, and in particular, developed-developing country partnerships. Standard database and web-based searches were conducted for publications in English between 1990 and 2010. Studies containing full or partial data relating to international cooperation between developed and developing countries were retained for further analysis. Of 227 articles retained through initial screening, 65 were included in the final analysis. The results were two-fold: some articles pointed to intangible benefits accrued by developed country partners, but the majority of information pointed to developing country innovations that can potentially inform health systems in developed countries. This information spanned all six WHO health system components. Ten key health areas where developed countries have the most to learn from the developing world were identified and include, rural health service delivery; skills substitution; decentralisation of management; creative problem-solving; education in communicable disease control; innovation in mobile phone use; low technology simulation training; local product manufacture; health financing; and social entrepreneurship. While there are no guarantees that innovations from developing country experiences can effectively transfer to developed countries, combined developed-developing country learning processes can potentially generate effective solutions for global health systems. However, the global pool of knowledge in this area is virgin and further work needs to be undertaken to advance understanding of health innovation diffusion. Even more urgently, a standardized method for reporting partnership benefits is needed--this is perhaps the single most immediate need in planning for, and realizing, the full potential of international cooperation between developed and developing countries.

Validity and reliability of Arabic MOS social support survey.

PubMed

Dafaalla, Mohamed; Farah, Abdulraheem; Bashir, Sheima; Khalil, Ammar; Abdulhamid, Rabab; Mokhtar, Mousab; Mahadi, Mohamed; Omer, Zulfa; Suliman, Asgad; Elkhalifa, Mohammed; Abdelgadir, Hanin; Kheir, Abdelmoneim E M; Abdalrahman, Ihab

2016-01-01

We aimed to generate a valid reliable Arabic version of MOS social support survey (MOS-SSS). We did a cross sectional study in medical students of Faculty of Medicine in Khartoum, Sudan. We did a clustered random sampling in 500 students of which 487 were suitable for analysis. We followed the standard translation process for translating the MOS-SSS. We accomplished factor analysis to assess construct validity, and generated item-scales correlations to evaluate the convergent and discriminant validity. We extracted the Cronbach's α and Spearman Brown coefficient of spit half method to determine internal consistency. We measured stability by correlation between the scores of the MOS survey taken at two different occasions with ten days apart in 252 participants. All items correlated highly (0.788 or greater) with their hypothesized scales. All items in subscales correlated higher by two standard errors with their own scale than with any other scale. Principle component analysis with varimax rotation was conducted on the 19 items and examination of scree plot graphically suggested 4 predominant factors that account for 72 % of variance. It showed high loadings, ranging from 0.720 to 0.84 for items of emotional support, 0.699-0.845 for tangible support, 0.518-0.823 for affectionate support, and 0.740-0.816 for positive social interaction. Cronbach's alpha for overall MOS scale and subscales indicated high internal consistency. The test-retest correlation showed weak correlation between the test and retest (ranges from 0.04 to 0.104). The Arabic MOS-SSS had high validity and internal consistency.

Multiple piece turbine engine airfoil with a structural spar

DOEpatents

Vance, Steven J [Orlando, FL

2011-10-11

A multiple piece turbine airfoil having an outer shell with an airfoil tip that is attached to a root with an internal structural spar is disclosed. The root may be formed from first and second sections that include an internal cavity configured to receive and secure the one or more components forming the generally elongated airfoil. The internal structural spar may be attached to an airfoil tip and place the generally elongated airfoil in compression. The configuration enables each component to be formed from different materials to reduce the cost of the materials and to optimize the choice of material for each component.

International VLBI Service for Geodesy and Astronomy

NASA Technical Reports Server (NTRS)

Vandenberg, Nancy R. (Editor); Baver, Karen D. (Editor)

2004-01-01

This volume of reports is the 2003 Annual Report of the International VLBI Service for Geodesy and Astrometry (IVS). The individual reports were contributed by VLBI groups in the international geodetic and astrometric community who constitute the permanent components of IVS. The IVS 2003 Annual Report documents the work of the IVS components for the calendar year 2003, our fifih year of existence. The reports describe changes, activities, and progress of the IVS. Many thanks to all IVS components who contributed to this Annual Report. The entire contents of this Annual Report also appear on the IVS web site at http://ivscc.gsfc.nasa.gov/publications/ar2OO3

Thermoelectric Generator Used in Fire-Alarm Temperature Sensing

NASA Astrophysics Data System (ADS)

Wu, Wenchang; Du, Zhengliang; Cui, Jiaolin; Shi, Zhongtao; Deng, Yuan

2015-06-01

Here we present a thermoelectric (TE) generator used in fire-alarm temperature sensing. The TE module, a core component of this generator, has a sandwich-like structure consisting of a Cu/Sn95Ag5/coated Ni/sprayed Ni/TE/sprayed Ni/coated Ni/Sn95Ag5/Cu multilayer that exhibits a low internal resistance of 5.5 Ω to 5.9 Ω and a contact resistance of 0.51 Ω to 0.91 Ω at room temperature (RT), enabling the TE generator to attain an open-circuit voltage ( V op) of 1.50 V at RT and 2.97 V at ~90°C. Moreover, its maximum output power ( p max) was estimated to be 11.6 mW and 428.7 mW, respectively, for a temperature difference (Δ T) of 9.3°C and 52.9°C. These values are comparable to those for the bulk TE generator developed by Thermonamic. According to these figures, we obtain corresponding power densities of ~7.25 × 103 nW/mm2 and 2.68 × 105 nW/mm2, respectively. Although there is still much room to improve the performance of the generator when the source temperature rises above 90°C, the output voltages and maximum output powers attained in the current testing conditions are large enough to drive small electronic devices such as fire-alarm systems etc. Therefore, it is believed that the fabrication technology and designed structure of the generator are appropriate for such applications.

A Second-Generation Volatile Organic Analyzer for the International Space Station

NASA Technical Reports Server (NTRS)

Limero, Thomas; Reese, Eric; Peters, Randy; James, John T.

1999-01-01

Early in the development of the Crew Health Care System (CHECS) for the International Space Station (ISS), it was recognized that detection of target volatile organic compounds would be a key component of the air monitoring strategy. Experiences during the NASA/Mir program supported the decision to include a real-time volatile organic analyzer (VOA) aboard ISS to help assess the impact of air quality events on crew health and determine the effectiveness of decontamination efforts. Toward this end, a joint development by the Toxicology Laboratory at Johnson Space Center and Graseby Dynamics produced a VOA that has been delivered and is ready for the first 5 years of ISS operation. The first-generation VOA selection criteria included minimizing size, weight, and power consumption while maintaining analytical performance. Measuring available technologies against these criteria, a VOA system based upon gas chromatography/ion mobility spectrometry (GC/IMS) was selected in the mid-90's. However, as NASA looks forward to later-stage ISS operations and to new frontiers such as human exploration of Mars, the ISS VOA (weighing 43 kg and consuming 160 watts) must be replaced by a smaller, less resource-intensive device. This paper will present a possible second-gene ration VOA based upon the same technology as the first-generation unit. Utilizing GC/IMS technology again will permit the instrumental data and experience gained during the initial phase of ISS to be applied to later ISS phases and advanced spacecraft missions. During the past 3 years, efforts to reduce the size of ion mobility spectrometers have been pursued by Graseby Dynamics, the manufacturer of the first-generation VOA. The concept of operation, expected analytical performance, and estimated size of a fully functional second-generation VOA based upon GC/mini-IMS technology will be presented. Furthermore, results of initial laboratory evaluations will be shown.

78 FR 57414 - Certain Video Game Systems and Wireless Controllers and Components Thereof, Commission...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-18

... INTERNATIONAL TRADE COMMISSION [Investigation No. 337-TA-770] Certain Video Game Systems and Wireless Controllers and Components Thereof, Commission Determination Finding No Violation of the Tariff Act of 1930 AGENCY: U.S. International Trade Commission. ACTION: Notice. SUMMARY: Notice is hereby...

78 FR 63492 - Certain Electronic Devices, Including Mobile Phones and Tablet Computers, and Components Thereof...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-24

... INTERNATIONAL TRADE COMMISSION [Investigation No. 337-TA-847] Certain Electronic Devices, Including Mobile Phones and Tablet Computers, and Components Thereof; Notice of Request for Statements on the Public Interest AGENCY: U.S. International Trade Commission. ACTION: Notice. SUMMARY: Notice is...

78 FR 77166 - Certain Optoelectronic Devices for Fiber Optic Communications, Components Thereof, and Products...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-20

... INTERNATIONAL TRADE COMMISSION [Investigation No. 337-TA-860] Certain Optoelectronic Devices for Fiber Optic Communications, Components Thereof, and Products Containing the Same; Notice of Request for Statements on the Public Interest AGENCY: U.S. International Trade Commission. ACTION: Notice. SUMMARY...

78 FR 20137 - Certain Sleep-Disordered Breathing Treatment Systems and Components Thereof; Notice of Receipt of...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-03

... INTERNATIONAL TRADE COMMISSION [Docket No. 2948] Certain Sleep-Disordered Breathing Treatment... given that the U.S. International Trade Commission has received a complaint entitled Certain Sleep... United States after importation of certain sleep- disordered breathing treatment systems and components...

RQ-21A Blackjack Small Tactical Unmanned Aircraft System (STUAS): Initial Operational Test and Evaluation Report

DTIC Science & Technology

2015-06-29

requirements for the system’s ground components to the generating capabilities of standard Marine Corps generators ). The Navy did not fully address two...dedicated generators to power the ground control stations. Recommendations The Navy and Marine Corps should consider the following recommendations in...components to the generating capabilities of standard Marine Corps generators ). The Navy did not fully address two recommendations (strengthening

Cell wall proteins of Sporothrix schenckii as immunoprotective agents.

PubMed

Alba-Fierro, Carlos A; Pérez-Torres, Armando; López-Romero, Everardo; Cuéllar-Cruz, Mayra; Ruiz-Baca, Estela

2014-01-01

Sporothrix schenckii is the etiological agent of sporotrichosis, an endemic subcutaneous mycosis in Latin America. Cell wall (CW) proteins located on the cell surface are inducers of cellular and humoral immune responses, potential candidates for diagnosis purposes and to generate vaccines to prevent fungal infections. This mini-review emphasizes the potential use of S. schenckii CW proteins as protective and therapeutic immune response inducers against sporotrichosis. A number of pathogenic fungi display CW components that have been characterized as inducers of protective cellular and humoral immune responses against the whole pathogen from which they were originally purified. The isolation and characterization of immunodominant protein components of the CW of S. schenckii have become relevant because of their potential in the development of protective and therapeutic immune responses against sporotrichosis. This manuscript is part of the series of works presented at the "V International Workshop: Molecular genetic approaches to the study of human pathogenic fungi" (Oaxaca, Mexico, 2012). Copyright © 2013 Revista Iberoamericana de Micología. Published by Elsevier Espana. All rights reserved.

Preliminary design of an auxiliary power unit for the space shuttle: Component and system configuration screening analysis

NASA Technical Reports Server (NTRS)

Binsley, R. L.; Maddox, J. P.; Marcy, R. D.; Siegler, R. S.; Spies, R.

1971-01-01

The auxiliary power unit (APU) for the space shuttle is required to provide hydraulic and electrical power on board the booster and orbiter vehicles. Five systems and their associated components, which utilize hot gas turbines to supply horsepower at gearbox output pads, were studied. Hydrogen-oxygen and storable propellants were considered for the hot gas supply. All APU's were required to be self-contained with respect to dissipating internally generated heat. These five systems were evaluated relative to a consistent criteria. The system supplied with high pressure gaseous hydrogen and oxygen was recommended as the best approach. It included a two-stage pressure-compounded partial-admission turbine, a propellant conditioning system with recuperation, a control system, and a gearbox. The gearbox output used was 240 hp. At the close of the study a 400 hp level was considered more appropriate for meeting the prime shuttle vehicle needs, and an in-depth analysis of the system at the 400 hp output level was recommended.

Pathogenesis of Systemic Sclerosis

PubMed Central

Pattanaik, Debendra; Brown, Monica; Postlethwaite, Bradley C.; Postlethwaite, Arnold E.

2015-01-01

Systemic scleroderma (SSc) is one of the most complex systemic autoimmune diseases. It targets the vasculature, connective tissue-producing cells (namely fibroblasts/myofibroblasts), and components of the innate and adaptive immune systems. Clinical and pathologic manifestations of SSc are the result of: (1) innate/adaptive immune system abnormalities leading to production of autoantibodies and cell-mediated autoimmunity, (2) microvascular endothelial cell/small vessel fibroproliferative vasculopathy, and (3) fibroblast dysfunction generating excessive accumulation of collagen and other matrix components in skin and internal organs. All three of these processes interact and affect each other. The disease is heterogeneous in its clinical presentation that likely reflects different genetic or triggering factor (i.e., infection or environmental toxin) influences on the immune system, vasculature, and connective tissue cells. The roles played by other ubiquitous molecular entities (such as lysophospholipids, endocannabinoids, and their diverse receptors and vitamin D) in influencing the immune system, vasculature, and connective tissue cells are just beginning to be realized and studied and may provide insights into new therapeutic approaches to treat SSc. PMID:26106387

Cermet coating tribological behavior in high temperature helium

DOE Office of Scientific and Technical Information (OSTI.GOV)

CACHON, Lionel; ALBALADEJO, Serge; TARAUD, Pascal

As the CEA is highly involved in the Generation IV Forum, a comprehensive research and development program has been conducted for several years, in order to establish the feasibility of Gas Cooled Reactor (GCR) technology projects using helium as a cooling fluid. Within this framework, a tribology program was launched in order to select and qualify coatings and materials, and to provide recommendations for the sliding components operating in GCRs. The purpose of this paper is to describe the CEA Helium tribology study on several GCR components (thermal barriers, control rod drive mechanisms, reactor internals, ..) requiring protection against wearmore » and bonding. Tests in helium atmosphere are necessary to be fully representative of tribological environments and to assess the material or coating candidates which can provide a reliable answer to these situations. This paper focuses on the tribology tests performed on CERMET (Cr{sub 3}C-2- NiCr) coatings within a temperature range of between 800 and 1000 deg C.« less

Low-threshold collinear parametric Raman comb generation in calcite under 532 and 1064 nm picosecond laser pumping

NASA Astrophysics Data System (ADS)

Smetanin, S. N.; Jelínek, M., Jr.; Kubeček, V.; Jelínková, H.

2015-09-01

Optimal conditions of low-threshold collinear parametric Raman comb generation in calcite (CaCO3) are experimentally investigated under 20 ps laser pulse excitation, in agreement with the theoretical study. The collinear parametric Raman generation of the highest number of Raman components in the short calcite crystals corresponding to the optimal condition of Stokes-anti-Stokes coupling was achieved. At the excitation wavelength of 1064 nm, using the optimum-length crystal resulted in the effective multi-octave frequency Raman comb generation containing up to five anti-Stokes and more than four Stokes components (from 674 nm to 1978 nm). The 532 nm pumping resulted in the frequency Raman comb generation from the 477 nm 2nd anti-Stokes up to the 692 nm 4th Stokes component. Using the crystal with a non-optimal length leads to the Stokes components generation only with higher thresholds because of the cascade-like stimulated Raman scattering with suppressed parametric coupling.

The International Haemovigilance Network Database for the Surveillance of Adverse Reactions and Events in Donors and Recipients of Blood Components: technical issues and results.

PubMed

Politis, C; Wiersum, J C; Richardson, C; Robillard, P; Jorgensen, J; Renaudier, P; Faber, J-C; Wood, E M

2016-11-01

The International Haemovigilance Network's ISTARE is an online database for surveillance of all adverse reactions (ARs) and adverse events (AEs) associated with donation of blood and transfusion of blood components, irrespective of severity or the harm caused. ISTARE aims to unify the collection and sharing of information with a view to harmonizing best practices for haemovigilance systems around the world. Adverse reactionss and adverse events are recorded by blood component, type of reaction, severity and imputability to transfusion, using internationally agreed standard definitions. From 2006 to 2012, 125 national sets of annual aggregated data were received from 25 countries, covering 132.8 million blood components issued. The incidence of all ARs was 77.5 per 100 000 components issued, of which 25% were severe (19.1 per 100 000). Of 349 deaths (0.26 per 100 000), 58% were due to the three ARs related to the respiratory system: transfusion-associated circulatory overload (TACO, 27%), transfusion-associated acute lung injury (TRALI, 19%) and transfusion-associated dyspnoea (TAD, 12%). Cumulatively, 594 477 donor complications were reported (rate 660 per 100 000), of which 2.9% were severe. ISTARE is a well-established surveillance tool offering important contributions to international efforts to maximize transfusion safety. © 2016 International Society of Blood Transfusion.

Role of nuclear grade graphite in controlling oxidation in modular HTGRs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Windes, Willaim; Strydom, G.; Kane, J.

2014-11-01

The passively safe High Temperature Gas-cooled Reactor (HTGR) design is one of the primary concepts considered for Generation IV and Small Modular Reactor (SMR) programs. The helium cooled, nuclear grade graphite moderated core achieves extremely high operating temperatures allowing either industrial process heat or electricity generation at high efficiencies. In addition to their neutron moderating properties, nuclear grade graphite core components provide excellent high temperature stability, thermal conductivity, and chemical compatibility with the high temperature nuclear fuel form. Graphite has been continuously used in nuclear reactors since the 1940’s and has performed remarkably well over a wide range of coremore » environments and operating conditions. Graphite moderated, gas-cooled reactor designs have been safely used for research and power production purposes in multiple countries since the inception of nuclear energy development. However, graphite is a carbonaceous material, and this has generated a persistent concern that the graphite components could actually burn during either normal or accident conditions [ , ]. The common assumption is that graphite, since it is ostensibly similar to charcoal and coal, will burn in a similar manner. While charcoal and coal may have the appearance of graphite, the internal microstructure and impurities within these carbonaceous materials are very different. Volatile species and trapped moisture provide a source of oxygen within coal and charcoal allowing them to burn. The fabrication process used to produce nuclear grade graphite eliminates these oxidation enhancing impurities, creating a dense, highly ordered form of carbon possessing high thermal diffusivity and strongly (covalently) bonded atoms.« less

Enhanced beam coupling modulation using the polarization properties of photorefractive GaAs

NASA Technical Reports Server (NTRS)

Partovi, Afshin; Garmire, Elsa M.; Cheng, Li-Jen

1987-01-01

Observation is reported of a rotation in the polarization of the two photorefractive recording beams in GaAs for a configuration with the internally generated space-charge field along the line 110 crystallographic orientation. This rotation is a result of simultaneous constructive and destructive beam coupling in each beam for the optical electric field components along the two electrooptically induced principal dielectric axes of the crystal. By turning one of the beams on and off, the intensity of the other beam after the crystal and a polarization analyzer can be modulated by as much as 500 percent. This result is of particular importance for optical information processing applications.

Micro-optics technology and sensor systems applications

NASA Technical Reports Server (NTRS)

Gal, George; Herman, B.; Anderson, W.; Whitney, R.; Morrow, H.

1993-01-01

The current generation of electro-optical sensors utilizing refractive and reflective optical elements require sophisticated, complex, and expensive designs. Advanced-technology-based electro-optical sensors of minimum size and weight require miniaturization of optical, electrical, and mechanical devices with an increasing trend toward integration of various components. Micro-optics technology has the potential in a number of areas to simplify optical design with improved performance. This includes internally cooled apertures, hybrid optical design, microlenses, dispersive multicolor microlenses, active dither, electronically controlled optical beam steer, and microscopic integration of micro-optics, detectors, and signal processing layers. This paper describes our approach to the development of micro-optics technology with our main emphasis for sensors applications.

Heat transfer of molten metal layers in severe accidents

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wong, Seung Kai; Walton, A.; Yang, Zhilin

1997-12-01

In some scenarios of severe accidents of light water reactors, a layer of molten metal from internal structural components of the pressure vessel is predicted to occur on top of a ceramic core debris in the lower head. The layer transfers the heat generated in the ceramic pool to the side wall of the vessel, causing the latter to melt. This problem has been investigated by Theofanous et al. for the advanced light water reactor AP600 in the context of the accident management strategy of ex-vessel cooling, and the conclusion was drawn that the melting does not seriously compromise themore » integrity of the pressure vessel.« less

Exercise countermeasures for long-duration spaceflight: muscle- and intensity-specific considerations

NASA Astrophysics Data System (ADS)

Trappe, Todd

2012-07-01

On-orbit and ground-based microgravity simulation studies have provided a wealth of information regarding the efficacy of exercise countermeasures for protecting skeletal muscle and cardiovascular function during long-duration spaceflights. While it appears that exercise will be the central component to maintaining skeletal muscle and cardiovascular health of astronauts, the current exercise prescription is not completely effective and is time consuming. This lecture will focus on recent exercise physiology studies examining high intensity, low volume exercise in relation to muscle specific and cardiovascular health. These studies provide the basis of the next generation exercise prescription currently being implemented during long-duration space missions on the International Space Station.

An Overview of Recent Phased Array Measurements at NASA Glenn

NASA Technical Reports Server (NTRS)

Podboy, Gary G.

2008-01-01

A review of measurements made at the NASA Glenn Research Center using an OptiNAV Array 48 phased array system is provided. Data were acquired on a series of round convergent and convergent-divergent nozzles using the Small Hot Jet Acoustic Rig. Tests were conducted over a range of jet operating conditions, including subsonic and supersonic and cold and hot jets. Phased array measurements were also acquired on a Williams International FJ44 engine. These measurements show how the noise generated by the engine is split between the inlet-radiated and exhaust-radiated components. The data also show inlet noise being reflected off of the inflow control device used during the test.

Early detection of sporadic pancreatic cancer: strategic map for innovation--a white paper.

PubMed

Kenner, Barbara J; Chari, Suresh T; Cleeter, Deborah F; Go, Vay Liang W

2015-07-01

Innovation leading to significant advances in research and subsequent translation to clinical practice is urgently necessary in early detection of sporadic pancreatic cancer. Addressing this need, the Early Detection of Sporadic Pancreatic Cancer Summit Conference was conducted by Kenner Family Research Fund in conjunction with the 2014 American Pancreatic Association and Japan Pancreas Society Meeting. International interdisciplinary scientific representatives engaged in strategic facilitated conversations based on distinct areas of inquiry: Case for Early Detection: Definitions, Detection, Survival, and Challenges; Biomarkers for Early Detection; Imaging; and Collaborative Studies. Ideas generated from the summit have led to the development of a Strategic Map for Innovation built upon 3 components: formation of an international collaborative effort, design of an actionable strategic plan, and implementation of operational standards, research priorities, and first-phase initiatives. Through invested and committed efforts of leading researchers and institutions, philanthropic partners, government agencies, and supportive business entities, this endeavor will change the future of the field and consequently the survival rate of those diagnosed with pancreatic cancer.

Early Detection of Sporadic Pancreatic Cancer

PubMed Central

Kenner, Barbara J.; Chari, Suresh T.; Cleeter, Deborah F.; Go, Vay Liang W.

2015-01-01

Abstract Innovation leading to significant advances in research and subsequent translation to clinical practice is urgently necessary in early detection of sporadic pancreatic cancer. Addressing this need, the Early Detection of Sporadic Pancreatic Cancer Summit Conference was conducted by Kenner Family Research Fund in conjunction with the 2014 American Pancreatic Association and Japan Pancreas Society Meeting. International interdisciplinary scientific representatives engaged in strategic facilitated conversations based on distinct areas of inquiry: Case for Early Detection: Definitions, Detection, Survival, and Challenges; Biomarkers for Early Detection; Imaging; and Collaborative Studies. Ideas generated from the summit have led to the development of a Strategic Map for Innovation built upon 3 components: formation of an international collaborative effort, design of an actionable strategic plan, and implementation of operational standards, research priorities, and first-phase initiatives. Through invested and committed efforts of leading researchers and institutions, philanthropic partners, government agencies, and supportive business entities, this endeavor will change the future of the field and consequently the survival rate of those diagnosed with pancreatic cancer. PMID:25938853

A review of human milk banking and public health policy in Australia.

PubMed

Lording, Roslyn J

2006-11-01

Breastmilk is the perfect food for human infants. It is markedly different from, and uniquely superior to, artificial baby milk. Human milk banks are services which collect, screen, process and distribute donated breastmilk. Recipients are generally ill and premature infants whose mothers are unable to breastfeed them. This review of human milk banking in Australian public health policy draws from local and international research. This history of human milk banking and contemporary Australian policies, pertaining to breastfeeding and milk banking, are examined. Human milk banking is noted to be largely invisible from national breastfeeding policies. The barriers to establishing human milk banks in the Australian context are explored. Strategies which have helped generate support for human milk banking are discussed. International research has demonstrated the cost-effectiveness of banked donor milk. It is time for human milk banking to become an integral component of Australian breastfeeding policies, viewed as one of several initiatives to protect and support breastfeeding.

Review of Potential Characterization Techniques in Approaching Energy and Sustainability

DOE PAGES

LePoire, David

2014-03-20

Societal prosperity is linked to sustainable energy and a healthy environment. But, tough global challenges include increased demand for fossil fuels, while approaching peak oil production and uncertainty in the environmental impacts of energy generation. Recently, energy use was identified as a major component of economic productivity, along with capital and labor. Furthermore, other environmental resources and impacts may be nearing environmental thresholds as indicated by nine planetary environmental boundaries, many of which are linked to energy production and use. Foresight techniques could be applied to guide future actions which include emphasis on (1) energy efficiency to bridge the transitionmore » to a renewable energy economy, (2) continued research, development, and assessment of new technologies, (3) improved understanding of environment impacts including natural capital use and degradation, (4) exploration of GDP alternative measures that include both economic production and environmental impacts, and (5) international cooperation and awareness of longer-term opportunities and their associated potential scenarios. Examples from the U.S. and the international community illustrate challenges and potential.« less

Technical Aspects of Acoustical Engineering for the ISS [International Space Station

NASA Technical Reports Server (NTRS)

Allen, Christopher S.

2009-01-01

It is important to control acoustic levels on manned space flight vehicles and habitats to protect crew-hearing, allow for voice communications, and to ensure a healthy and habitable environment in which to work and live. For the International Space Station (ISS) this is critical because of the long duration crew-stays of approximately 6-months. NASA and the JSC Acoustics Office set acoustic requirements that must be met for hardware to be certified for flight. Modules must meet the NC-50 requirement and other component hardware are given smaller allocations to meet. In order to meet these requirements many aspects of noise generation and control must be considered. This presentation has been developed to give an insight into the various technical activities performed at JSC to ensure that a suitable acoustic environment is provided for the ISS crew. Examples discussed include fan noise, acoustic flight material development, on-orbit acoustic monitoring, and a specific hardware development and acoustical design case, the ISS Crew Quarters.

Assessing sustainable remediation frameworks using sustainability principles.

PubMed

Ridsdale, D Reanne; Noble, Bram F

2016-12-15

The remediation industry has grown exponentially in recent decades. International organizations of practitioners and remediation experts have developed several frameworks for integrating sustainability into remediation projects; however, there has been limited attention to how sustainability is approached and operationalized in sustainable remediation frameworks and practices - or whether sustainability plays any meaningful role at all in sustainable remediation. This paper examines how sustainability is represented in remediation frameworks and the guidance provided for practical application. Seven broad sustainability principles and review criteria are proposed and applied to a sample of six international remediation frameworks. Not all review criteria were equally satisfied and none of the frameworks fully met all criteria; however, the best performing frameworks were those identified as sustainability remediation frameworks. Intra-generational equity was addressed by all frameworks. Integrating social, economic and biophysical components beyond triple-bottom-line indicators was explicitly addressed only by the sustainable remediation frameworks. No frameworks provided principle- or rule-based guidance for dealing with trade-offs in sustainability decisions. Copyright © 2016 Elsevier Ltd. All rights reserved.

Adjustable supercontinuum laser source with low coherence length and low timing jitter

NASA Astrophysics Data System (ADS)

Andreana, Marco; Bertrand, Anthony; Hernandez, Yves; Leproux, Philippe; Couderc, Vincent; Hilaire, Stéphane; Huss, Guillaume; Giannone, Domenico; Tonello, Alessandro; Labruyère, Alexis; Rongeat, Nelly; Nérin, Philippe

2010-04-01

This paper introduces a supercontinuum (SC) laser source emitting from 400 nm to beyond 1750 nm, with adjustable pulse repetition rate (from 250 kHz to 1 MHz) and duration (from ~200 ps to ~2 ns). This device makes use of an internally-modulated 1.06 μm semiconductor laser diode as pump source. The output radiation is then amplified through a preamplifier (based on single-mode Yb-doped fibres) followed by a booster (based on a double-clad Yb-doped fibre). The double-clad fibre output is then spliced to an air-silica microstructured optical fibre (MOF). The small core diameter of the double-clad fibre allows reducing the splice loss. The strongly nonlinear propagation regime in the MOF leads to the generation of a SC extending from the violet to the nearinfrared wavelengths. On the Stokes side of the 1.06 μm pump line, i.e., in the anomalous dispersion regime, the spectrum is composed of an incoherent distribution of quasi-solitonic components. Therefore, the SC source is characterised by a low coherence length, which can be tuned by simply modifying pulse duration, that is closely related to the number of quasi-solitonic components brought into play. Finally, the internal modulation of the laser diode permits to achieve excellent temporal stability, both in terms of average power and pulse-to-pulse period.

Tetris Is a Foldback Transposon that Provided the Building Blocks for an Emerging Satellite DNA of Drosophila virilis

PubMed Central

Dias, Guilherme B.; Svartman, Marta; Delprat, Alejandra; Ruiz, Alfredo; Kuhn, Gustavo C.S.

2014-01-01

Transposable elements (TEs) and satellite DNAs (satDNAs) are abundant components of most eukaryotic genomes studied so far and their impact on evolution has been the focus of several studies. A number of studies linked TEs with satDNAs, but the nature of their evolutionary relationships remains unclear. During in silico analyses of the Drosophila virilis assembled genome, we found a novel DNA transposon we named Tetris based on its modular structure and diversity of rearranged forms. We aimed to characterize Tetris and investigate its role in generating satDNAs. Data mining and sequence analysis showed that Tetris is apparently nonautonomous, with a structure similar to foldback elements, and present in D. virilis and D. americana. Herein, we show that Tetris shares the final portions of its terminal inverted repeats (TIRs) with DAIBAM, a previously described miniature inverted transposable element implicated in the generation of chromosome inversions. Both elements are likely to be mobilized by the same autonomous TE. Tetris TIRs contain approximately 220-bp internal tandem repeats that we have named TIR-220. We also found TIR-220 repeats making up longer (kb-size) satDNA-like arrays. Using bioinformatic, phylogenetic and cytogenomic tools, we demonstrated that Tetris has contributed to shaping the genomes of D. virilis and D. americana, providing internal tandem repeats that served as building blocks for the amplification of satDNA arrays. The β-heterochromatic genomic environment seemed to have favored such amplification. Our results imply for the first time a role for foldback elements in generating satDNAs. PMID:24858539

Salience of Somatosensory Stimulus Modulating External-to-Internal Orienting Attention.

PubMed

Peng, Jiaxin; Chan, Sam C C; Chau, Bolton K H; Yu, Qiuhua; Chan, Chetwyn C H

2017-01-01

Shifting between one's external and internal environments involves orienting attention. Studies on differentiating subprocesses associated with external-to-internal orienting attention are limited. This study aimed to reveal the characteristics of the disengagement, shifting and reengagement subprocesses by using somatosensory external stimuli and internally generated images. Study participants were to perceive nociceptive external stimuli (External Low (E L ) or External High (E H )) induced by electrical stimulations (50 ms) followed by mentally rehearsing learned subnociceptive images (Internal Low (I L ) and Internal High (I H )). Behavioral responses and EEG signals of the participants were recorded. The three significant components elicited were: fronto-central negativity (FCN; 128-180 ms), fronto-central P2 (200-260 ms), and central P3 (320-380 ms), which reflected the three subprocesses, respectively. Differences in the FCN and P2 amplitudes during the orienting to the subnociceptive images revealed only in the E H but not E L stimulus condition that are new findings. The results indicated that modulations of the disengagement and shifting processes only happened if the external nociceptive stimuli were of high salience and the external-to-internal incongruence was large. The reengaging process reflected from the amplitude of P3 correlated significantly with attenuation of the pain intensity felt from the external nociceptive stimuli. These findings suggested that the subprocesses underlying external-to-internal orienting attention serve different roles. Disengagement subprocess tends to be stimulus dependent, which is bottom-up in nature. Shifting and reengagement tend to be top-down subprocesses, which taps on cognitive control. This subprocess may account for the attenuation effects on perceived pain intensity after orienting attention.

Salience of Somatosensory Stimulus Modulating External-to-Internal Orienting Attention

PubMed Central

Peng, Jiaxin; Chan, Sam C. C.; Chau, Bolton K. H.; Yu, Qiuhua; Chan, Chetwyn C. H.

2017-01-01

Shifting between one’s external and internal environments involves orienting attention. Studies on differentiating subprocesses associated with external-to-internal orienting attention are limited. This study aimed to reveal the characteristics of the disengagement, shifting and reengagement subprocesses by using somatosensory external stimuli and internally generated images. Study participants were to perceive nociceptive external stimuli (External Low (EL) or External High (EH)) induced by electrical stimulations (50 ms) followed by mentally rehearsing learned subnociceptive images (Internal Low (IL) and Internal High (IH)). Behavioral responses and EEG signals of the participants were recorded. The three significant components elicited were: fronto-central negativity (FCN; 128–180 ms), fronto-central P2 (200–260 ms), and central P3 (320–380 ms), which reflected the three subprocesses, respectively. Differences in the FCN and P2 amplitudes during the orienting to the subnociceptive images revealed only in the EH but not EL stimulus condition that are new findings. The results indicated that modulations of the disengagement and shifting processes only happened if the external nociceptive stimuli were of high salience and the external-to-internal incongruence was large. The reengaging process reflected from the amplitude of P3 correlated significantly with attenuation of the pain intensity felt from the external nociceptive stimuli. These findings suggested that the subprocesses underlying external-to-internal orienting attention serve different roles. Disengagement subprocess tends to be stimulus dependent, which is bottom-up in nature. Shifting and reengagement tend to be top-down subprocesses, which taps on cognitive control. This subprocess may account for the attenuation effects on perceived pain intensity after orienting attention. PMID:28970787

Payload Planning for the International Space Station

NASA Technical Reports Server (NTRS)

Johnson, Tameka J.

1995-01-01

A review of the evolution of the International Space Station (ISS) was performed for the purpose of understanding the project objectives. It was requested than an analysis of the current Office of Space Access and Technology (OSAT) Partnership Utilization Plan (PUP) traffic model be completed to monitor the process through which the scientific experiments called payloads are manifested for flight to the ISS. A viewing analysis of the ISS was also proposed to identify the capability to observe the United States Laboratory (US LAB) during the assembly sequence. Observations of the Drop-Tower experiment and nondestructive testing procedures were also performed to maximize the intern's technical experience. Contributions were made to the meeting in which the 1996 OSAT or Code X PUP traffic model was generated using the software tool, Filemaker Pro. The current OSAT traffic model satisfies the requirement for manifesting and delivering the proposed payloads to station. The current viewing capability of station provides the ability to view the US LAB during station assembly sequence. The Drop Tower experiment successfully simulates the effect of microgravity and conveniently documents the results for later use. The non-destructive test proved effective in determining stress in various components tested.

Solid tags for identifying failed reactor components

DOEpatents

Bunch, Wilbur L.; Schenter, Robert E.

1987-01-01

A solid tag material which generates stable detectable, identifiable, and measurable isotopic gases on exposure to a neutron flux to be placed in a nuclear reactor component, particularly a fuel element, in order to identify the reactor component in event of its failure. Several tag materials consisting of salts which generate a multiplicity of gaseous isotopes in predetermined ratios are used to identify different reactor components.

Flight set 360L001 (STS-26) insulation component. Volume 3: Final release

NASA Technical Reports Server (NTRS)

Albrechtsen, K.; Passman, J.

1989-01-01

The postfire condition of the external and internal insulation for STS-26 is documented and the thermal safety factors of the RSRM-1A and RSRM-1B internal insulation are evaluated. The Insulation Component Program Team assessment of the observation is discussed.

77 FR 28622 - Certain Gaming and Entertainment Consoles, Related Software, and Components Thereof; Notice of...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-15

... INTERNATIONAL TRADE COMMISSION [Investigation No. 337-TA-752] Certain Gaming and Entertainment Consoles, Related Software, and Components Thereof; Notice of Request for Statements on the Public Interest AGENCY: U.S. International Trade Commission. ACTION: Notice. SUMMARY: Notice is hereby given that the...

77 FR 68829 - Certain Electronic Digital Media Devices and Components Thereof; Notice of Request for Statements...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-16

... INTERNATIONAL TRADE COMMISSION [Investigation No. 337-TA-796] Certain Electronic Digital Media... electronic digital media devices and components thereof imported by respondents Samsung Electronics Co, Ltd... Samsung. FOR FURTHER INFORMATION CONTACT: Cathy Chen, Office of the General Counsel, U.S. International...

78 FR 50445 - Certain Computers and Computer Peripheral Devices and Components Thereof and Products Containing...

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2013-08-19

... INTERNATIONAL TRADE COMMISSION [Investigation No. 337-TA-841] Certain Computers and Computer Peripheral Devices and Components Thereof and Products Containing the Same Request for Statements on the Public Interest AGENCY: U.S. International Trade Commission. ACTION: Notice. SUMMARY: Notice is hereby...

Examinations for leak tightness of actively cooled components in ITER and fusion devices

NASA Astrophysics Data System (ADS)

Hirai, T.; Barabash, V.; Carrat, R.; Chappuis, Ph; Durocher, A.; Escourbiac, F.; Merola, M.; Raffray, R.; Worth, L.; Boscary, J.; Chantant, M.; Chuilon, B.; Guilhem, D.; Hatchressian, J.-C.; Hong, S. H.; Kim, K. M.; Masuzaki, S.; Mogaki, K.; Nicolai, D.; Wilson, D.; Yao, D.

2017-12-01

Any leak in one of the ITER actively cooled components would cause significant consequences for machine operations; therefore, the risk of leak must be minimized as much as possible. In this paper, the strategy of examination to ensure leak tightness of the ITER internal components (i.e. examination of base materials, vacuum boundary joints and final components) and the hydraulic parameters for ITER internal components are summarized. The experiences of component tests, especially hot helium leak tests in recent fusion devices, were reviewed and the parameters were discussed. Through these experiences, it was confirmed that the hot He leak test was effective to detect small leak paths which were not always possible to detect by volumetric examination due to limited spatial resolution.

South Asian women: identities and conflicts.

PubMed

Inman, Arpana G

2006-04-01

This study investigated the effects of education, level of religiosity, ethnic identity (internal and external), and racial identity statuses (conformity, dissonance, resistance, and awareness) on cultural value conflict for first and second generation South Asian women (N = 193). Cultural value conflict was examined in two areas, intimate relations and sex-role expectations. Results revealed that level of religiosity was more predictive of intimate relations conflict for second generation than first generation women. Furthermore, higher ratings in internal ethnic identity predicted greater intimate relations conflict in first generation women, while both internal and external ethnic identity predicted intimate relations conflict in second generation women. Finally, higher dissonance scores in racial identity predicted greater conflicts in sex-role expectations for second generation women alone.

Inside-out: comparing internally generated and externally generated basic emotions.

PubMed

Salas, Christian E; Radovic, Darinka; Turnbull, Oliver H

2012-06-01

A considerable number of mood induction (MI) procedures have been developed to elicit emotion in normal and clinical populations. Although external procedures (e.g., film clips, pictures) are widely used, a number of experiments elicit emotion by using self-generated procedures (e.g., recalling an emotional personal episode). However, no study has directly compared the effectiveness of two types of internal versus external MI across multiple discrete emotions. In the present experiment, 40 undergraduate students watched film clips (external procedure) and recalled personal events (internal procedure) inducing 4 basic emotions (fear, anger, joy, sadness) and later completed a self-report questionnaire. Remarkably, both internal and external procedures elicited target emotions selectively, compared with nontarget emotions. When contrasting the intensity of target emotions, both techniques showed no significant differences, with the exception of Joy, which was more intensely elicited by the internal procedure. Importantly, when considering the overall level of intensity, it was always greater in the internal procedure, for each stimulus. A more detailed investigation of the data suggest that recalling personal events (a type of internal procedure) generates more negative and mixed blends of emotions, which might account for the overall higher intensity of the internal mood induction.

Research environments that promote integrity.

PubMed

Jeffers, Brenda Recchia; Whittemore, Robin

2005-01-01

The body of empirical knowledge about research integrity and the factors that promote research integrity in nursing research environments remains small. To propose an internal control model as an innovative framework for the design and structure of nursing research environments that promote integrity. An internal control model is adapted to illustrate its use for conceptualizing and designing research environments that promote integrity. The internal control model integrates both the organizational elements necessary to promote research integrity and the processes needed to assess research environments. The model provides five interrelated process components within which any number of research integrity variables and processes may be used and studied: internal control environment, risk assessment, internal control activities, monitoring, and information and communication. The components of the proposed research integrity internal control model proposed comprise an integrated conceptualization of the processes that provide reasonable assurance that research integrity will be promoted within the nursing research environment. Schools of nursing can use the model to design, implement, and evaluate systems that promote research integrity. The model process components need further exploration to substantiate the use of the model in nursing research environments.

Development of a 13 kW Hall Thruster Propulsion System Performance Model for AEPS

NASA Technical Reports Server (NTRS)

Stanley, Steven; Allen, May; Goodfellow, Keith; Chew, Gilbert; Rapetti, Ryan; Tofil, Todd; Herman, Dan; Jackson, Jerry; Myers, Roger

2017-01-01

The Advanced Electric Propulsion System (AEPS) program will develop a flight 13kW Hall thruster propulsion system based on NASA's HERMeS thruster. The AEPS system includes the Hall Thruster, the Power Processing Unit (PPU) and the Xenon Flow Controller (XFC). These three primary components must operate together to ensure that the system generates the required combinations of thrust and specific impulse at the required system efficiencies for the desired system lifetime. At the highest level, the AEPS system will be integrated into the spacecraft and will receive power, propellant, and commands from the spacecraft. Power and propellant flow rates will be determined by the throttle set points commanded by the spacecraft. Within the system, the major control loop is between the mass flow rate and thruster current, with time-dependencies required to handle all expected transients, and additional, much slower interactions between the thruster and cathode temperatures, flow controller and PPU. The internal system interactions generally occur on shorter timescales than the spacecraft interactions, though certain failure modes may require rapid responses from the spacecraft. The AEPS system performance model is designed to account for all these interactions in a way that allows evaluation of the sensitivity of the system to expected changes over the planned mission as well as to assess the impacts of normal component and assembly variability during the production phase of the program. This effort describes the plan for the system performance model development, correlation to NASA test data, and how the model will be used to evaluate the critical internal and external interactions. The results will ensure the component requirements do not unnecessarily drive the system cost or overly constrain the development program. Finally, the model will be available to quickly troubleshoot any future unforeseen development challenges.

Validation of an automated electronic algorithm and "dashboard" to identify and characterize decompensated heart failure admissions across a medical center.

PubMed

Cox, Zachary L; Lewis, Connie M; Lai, Pikki; Lenihan, Daniel J

2017-01-01

We aim to validate the diagnostic performance of the first fully automatic, electronic heart failure (HF) identification algorithm and evaluate the implementation of an HF Dashboard system with 2 components: real-time identification of decompensated HF admissions and accurate characterization of disease characteristics and medical therapy. We constructed an HF identification algorithm requiring 3 of 4 identifiers: B-type natriuretic peptide >400 pg/mL; admitting HF diagnosis; history of HF International Classification of Disease, Ninth Revision, diagnosis codes; and intravenous diuretic administration. We validated the diagnostic accuracy of the components individually (n = 366) and combined in the HF algorithm (n = 150) compared with a blinded provider panel in 2 separate cohorts. We built an HF Dashboard within the electronic medical record characterizing the disease and medical therapies of HF admissions identified by the HF algorithm. We evaluated the HF Dashboard's performance over 26 months of clinical use. Individually, the algorithm components displayed variable sensitivity and specificity, respectively: B-type natriuretic peptide >400 pg/mL (89% and 87%); diuretic (80% and 92%); and International Classification of Disease, Ninth Revision, code (56% and 95%). The HF algorithm achieved a high specificity (95%), positive predictive value (82%), and negative predictive value (85%) but achieved limited sensitivity (56%) secondary to missing provider-generated identification data. The HF Dashboard identified and characterized 3147 HF admissions over 26 months. Automated identification and characterization systems can be developed and used with a substantial degree of specificity for the diagnosis of decompensated HF, although sensitivity is limited by clinical data input. Copyright © 2016 Elsevier Inc. All rights reserved.

DPOAE generation dependence on primary frequencies ratio

NASA Astrophysics Data System (ADS)

Botti, Teresa; Sisto, Renata; Moleti, Arturo; D'Amato, Luisa; Sanjust, Filippo

2015-12-01

Two different mechanisms are responsible for the DPOAE generation. The nonlinear distortion wave-fixed mechanism generates the DPOAE Zero-Latency (ZL) component, as a backward traveling wave from the "overlap" region. Linear reflection of the forward DP wave (IDP) generates the DPOAE Long-Latency (LL) component through a place-fixed mechanism. ZL and LL components add up vectorially to generate the DPOAE recorded in the ear canal. The 2f1 - f2 and 2f2 - f1 DPOAE intensity depends on the stimulus level and on the primary frequency ratio r = f2/f1, where f1 and f2 are the primary stimuli frequencies. Here we study the behavior of the ZL and LL DPOAE components as a function of r by both numerical and laboratory experiments, measuring DPAOEs with an equal primary levels (L1 = L2) paradigm in the range [35, 75] dB SPL, with r ranging in [1.1, 1.45]. Numerical simulations of a nonlocal nonlinear model have been performed without cochlear roughness, to suppress the linear reflection mechanism. In this way the model solution at the base represents the DPOAE ZL component, and the solution at the corresponding DPOAE tonotopic place corresponds to the IDP. This technique has been not effectual to study the 2f2 - f1 DPOAE, as a consequence of its generation mechanism. While the 2f1 - f2 generation place is known to be the tonotopic place x(f2), the 2f2 - f1 DPOAE one has to be assumed basal to its corresponding reflection place. That is because ZL components generated in x(f2) cannot significantly pass through their resonant place. Moreover increasing the ratio r, 2f2 - f1 ZL and LL generation place approach each other, because the overlap region of primary tones decreases. Consequently, the distinction between the two places becomes complicated. DPOAEs have been measured in six young normal-hearing subjects. DPOAE ZL and LL components have been separated by a time-frequency filtering method based on the wavelet transform 1. due to their different phase gradient delay. Amplitude/phase vs ratio and ratio-frequency maps have been analyzed both in numerical and laboratory data. As already observed in animal studies [4], the generation of 2f1 - f2 DPOAE is around the f2 tonotopic place with a maximum around r = 1.2 for the ZL component, while the LL component shows a decreasing trend with r. Instead, 2f2 - f1 DPOAEs show a decreasing trend with r for both ZL and LL components.

Tolerance measurements on internal- and external-hexagon implants.

PubMed

Braian, Michael; De Bruyn, Hugo; Fransson, Håkan; Christersson, Cecilia; Wennerberg, Ann

2014-01-01

To measure the horizontal machining tolerances of the interface between internal- and external-hexagon implants and analogs with corresponding components after delivery from the manufacturer. These values may be a valuable tool for evaluating increasing misfit caused by fabrication, processing, and wear. Seven implants and seven analogs with external- and internal-hexagon connections (Biomet 3i) with corresponding prefabricated gold cylinders and gold screws, prefabricated cylindric plastic cylinders, and laboratory screws were studied. One set of components from the external and internal groups was measured manually and digitally. Measurements from the test subjects were compared with identical measurements from the virtual model to obtain threshold values. The virtual model was then used to obtain optimally oriented cuts. The horizontal machining tolerances for castable plastic abutments on external implants were 12 ± 89 μm, and for internal implants they were 86 ± 47 μm. Tolerance measurements on prefabricated gold abutments for external implants were 44 ± 9 μm, and for internal implants they were 58 ± 28 μm. The groups with metallic components showed the smallest tolerance at < 50 μm for the external group and < 90 μm for the internal group. The prefabricated plastic cylinder groups ranged from < 100 μm for external and < 130 μm for internal connection.

Intergenerational payoffs of education.

PubMed

Kaushal, Neeraj

2014-01-01

Better-educated parents generally have children who are themselves better educated, healthier, wealthier, and better off in almost every way than the children of the less educated. But this simple correlation does not prove that the relationship is causal. Neeraj Kaushal sifts through the evidence from economics and public policy and reviews large national and international studies to conclude that, indeed, education has large intergenerational payoffs in many areas of children's lives, and that these payoffs persist over time. Kaushal shows that, if anything, traditional measures of returns to education--which focus on income and productivity--almost certainly underestimate the beneficial effects that parents' education has on their children. She reports causal positive effects not only on children's test scores, health, and behavior, but also on mothers' behaviors that can affect their children's wellbeing, such as teenage childbearing and substance use. Her findings suggest that, as a component of two-generation programs, helping parents extend their education could go a long way toward reducing inequality across generations and promoting children's healthy development. Thus the rationale for two-generation programs that boost parents' education is compelling. However, Kaushal cautions, the U.S. education system reinforces socioeconomic inequality across generations by spending more money on educating richer children than on educating poorer children. By themselves, then, two-generation programs will not necessarily ameliorate the structural factors that perpetuate inequality in this country.

Gαs regulates Glucagon-Like Peptide 1 Receptor-mediated cyclic AMP generation at Rab5 endosomal compartment.

PubMed

Girada, Shravan Babu; Kuna, Ramya S; Bele, Shilpak; Zhu, Zhimeng; Chakravarthi, N R; DiMarchi, Richard D; Mitra, Prasenjit

2017-10-01

Upon activation, G protein coupled receptors (GPCRs) associate with heterotrimeric G proteins at the plasma membrane to initiate second messenger signaling. Subsequently, the activated receptor experiences desensitization, internalization, and recycling back to the plasma membrane, or it undergoes lysosomal degradation. Recent reports highlight specific cases of persistent cyclic AMP generation by internalized GPCRs, although the functional significance and mechanistic details remain to be defined. Cyclic AMP generation from internalized Glucagon-Like Peptide-1 Receptor (GLP-1R) has previously been reported from our laboratory. This study aimed at deciphering the molecular mechanism by which internalized GLP-R supports sustained cyclic AMP generation upon receptor activation in pancreatic beta cells. We studied the time course of cyclic AMP generation following GLP-1R activation with particular emphasis on defining the location where cyclic AMP is generated. Detection involved a novel GLP-1 conjugate coupled with immunofluorescence using specific endosomal markers. Finally, we employed co-immunoprecipitation as well as immunofluorescence to assess the protein-protein interactions that regulate GLP-1R mediated cyclic AMP generation at endosomes. Our data reveal that prolonged association of G protein α subunit Gαs with activated GLP-1R contributed to sustained cyclic AMP generation at Rab 5 endosomal compartment. The findings provide the mechanism of endosomal cyclic AMP generation following GLP-1R activation. We identified the specific compartment that serves as an organizing center to generate endosomal cyclic AMP by internalized activated receptor complex. Copyright © 2017 The Authors. Published by Elsevier GmbH.. All rights reserved.

Association of obesity and eating in the absence of hunger among college students in a Mexican-USA border city.

PubMed

Pérez-Morales, Eugenia; Jiménez-Cruz, Arturo; Alcántara-Jurado, Luis; Armendáriz-Anguiano, Ana; Bacardí-Gascón, Montserrat

2014-06-01

Few studies have examined disinhibited eating behaviors in Mexico. However eating in the absence of hunger (EAH), defined as eating in response to the presence of palatable foods in the absence of physiological hunger, is one of the more frequently examined behaviors. The purpose of this study was to assess the association between obesity and EAH among college students in a large Mexican-USA border city. Two-hundred and one sophomore college students completed the EAH questionnaire (EAH-C). Weight and height were measured. To assess reproducibility a test-retest was conducted in a subset sample (n = 20). Test-retest correlations ranged from ρ = 0.44 to 0.86, p < 0.01. Data obtained from the EAH-C were subjected to a principal components analysis with a varimax rotation. The mean age of participants was 21.0 ± 2.0 years, 52 % were female. The prevalence of overweight and obesity was 29 and 14 % respectively. The internal validity was assessed by Cronbach's alph. Internal consistency for all subscales was: external eating (α = 0.83), negative affect (α = 0.92) and fatigue/boredom (α = 0.86). Principal component analysis generated four subscales for the EAH-C: external eating, negative affect, fatigue and boredom. Comparing normal weight students versus obese students, normal weight students (57.1%) had higher scores on boredom subscale than obese students (p < 0.008). Female students had higher scores in the negative affect subscale than the males (p < 0.001). We conclude that the EAH-C had internal consistent subscales with good convergent validity. In this study population we found no association between EAH and obesity.

Defining Health Research for Development: The perspective of stakeholders from an international health research partnership in Ghana and Tanzania.

PubMed

Ward, Claire Leonie; Shaw, David; Anane-Sarpong, Evelyn; Sankoh, Osman; Tanner, Marcel; Elger, Bernice

2017-05-03

The study uses a qualitative empirical method to define Health Research for Development. This project explores the perspectives of stakeholders in an international health research partnership operating in Ghana and Tanzania. We conducted 52 key informant interviews with major stakeholders in an international multicenter partnership between GlaxoSmithKline (GSK, Vaccine Developer) and the global health nonprofit organisation PATH and its Malaria Vaccine Initiative program (PATH/MVI, Funder-Development Partner), (RTS, S) (NCT00866619). The respondents included teams from four clinical research centres (two centres in Ghana and two in Tanzania) and various collaborating partners. This paper analyses responses to the question: What is Health Research for Development? Based on the stakeholders' experience the respondents offered many ways of defining Health Research for Development. The responses fell into four broad themes: i) Equitable Partnerships; ii) System Sustainability; iii) Addressing Local Health Targets, and iv) Regional Commitment to Benefit Sharing. Through defining Health Research for Development six key learning points were generated from the four result themes: 1) Ensure there is local research leadership working with the collaborative partnership, and local healthcare system, to align the project agenda and activities with local research and health priorities; 2) Know the country-specific context - map the social, health, legislative and political setting; 3) Define an explicit development component and plan of action in a research project; 4) Address the barriers and opportunities to sustain system capacity. 5) Support decentralised health system decision-making to facilitate the translation pathway; 6) Govern, monitor and evaluate the development components of health research partnerships. Overall, equity and unity between partners are required to deliver health research for development. © 2017 John Wiley & Sons Ltd.

Mass and Reliability Source (MaRS) Database

NASA Technical Reports Server (NTRS)

Valdenegro, Wladimir

2017-01-01

The Mass and Reliability Source (MaRS) Database consolidates components mass and reliability data for all Oribital Replacement Units (ORU) on the International Space Station (ISS) into a single database. It was created to help engineers develop a parametric model that relates hardware mass and reliability. MaRS supplies relevant failure data at the lowest possible component level while providing support for risk, reliability, and logistics analysis. Random-failure data is usually linked to the ORU assembly. MaRS uses this data to identify and display the lowest possible component failure level. As seen in Figure 1, the failure point is identified to the lowest level: Component 2.1. This is useful for efficient planning of spare supplies, supporting long duration crewed missions, allowing quicker trade studies, and streamlining diagnostic processes. MaRS is composed of information from various databases: MADS (operating hours), VMDB (indentured part lists), and ISS PART (failure data). This information is organized in Microsoft Excel and accessed through a program made in Microsoft Access (Figure 2). The focus of the Fall 2017 internship tour was to identify the components that were the root cause of failure from the given random-failure data, develop a taxonomy for the database, and attach material headings to the component list. Secondary objectives included verifying the integrity of the data in MaRS, eliminating any part discrepancies, and generating documentation for future reference. Due to the nature of the random-failure data, data mining had to be done manually without the assistance of an automated program to ensure positive identification.

Scale/Analytical Analyses of Freezing and Convective Melting with Internal Heat Generation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ali S. Siahpush; John Crepeau; Piyush Sabharwall

2013-07-01

Using a scale/analytical analysis approach, we model phase change (melting) for pure materials which generate constant internal heat generation for small Stefan numbers (approximately one). The analysis considers conduction in the solid phase and natural convection, driven by internal heat generation, in the liquid regime. The model is applied for a constant surface temperature boundary condition where the melting temperature is greater than the surface temperature in a cylindrical geometry. The analysis also consider constant heat flux (in a cylindrical geometry).We show the time scales in which conduction and convection heat transfer dominate.

Environmental Cracking and Irradiation Resistant Stainless Steels by Additive Manufacturing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rebak, Raul B.; Lou, Xiaoyuan

Metal additive manufacturing (AM), or metal 3D printing is an emergent advanced manufacturing method that can create near net shape geometries directly from computer models. This technology can provide the capability to rapidly fabricate complex parts that may be required to enhance the integrity of reactor internals components. Such opportunities may be observed during a plant refueling outage and AM parts can be rapidly custom designed, manufactured and deployed within the outage interval. Additive manufacturing of stainless steel (SS) components can add business benefits on fast delivery on repair hardware, installation tooling, new design prototypes tests, etc. For the nuclearmore » industry, the supply chain is always an issue for reactor service. AM can provide through-life supply chain (40-60 years) for high-value low-volume components. In the meantime, the capability of generating complex geometries and functional gradient materials will improve the performance, reduce the overall component cost, plant asset management cost and increase the plant reliability by the improvement in materials performance in nuclear environments. While extensive work has been conducted regarding additively manufacturing of austenitic SS parts, most efforts focused only on basic attributes such as porosity, residual stress, basic tensile properties, along with components yield and process monitoring. Little work has been done to define and evaluate the material requirements for nuclear applications. Technical gaps exist, which limit this technology adoption in the nuclear industry, which includes high manufacturing cost, unknown risks, limited nuclear related data, lack of specification and qualification methods, and no prior business experience. The main objective of this program was to generate research data to address all these technical gaps and establish a commercial practice to use AM technology in the nuclear power industry. The detailed objectives are listed as follows: (1) Evaluate nuclear related properties of AM 316L SS, including microstructure, tensile properties, impact toughness, stress corrosion cracking (SCC), corrosion fatigue (CF), irradiation effects, and irradiation assisted stress corrosion cracking (IASCC). (2) Understand the correlations among laser processing, heat treatment, microstructure and SCC/irradiation properties; (3) Optimize and improve the manufacturing process to achieve enhanced nuclear application properties; (4) Fabricate, evaluate, qualify and test a prototype reactor component to demonstrate the commercial viability and cost benefit; (5) Create regulatory approval path and commercialization plans for the production of a commercial reactor component.« less

Internal gravity waves in the upper atmosphere, generated by tropospheric jet streams

NASA Technical Reports Server (NTRS)

Chunchuzov, Y. P.; Torgashin, Y. M.

1979-01-01

A mechanism of internal gravity wave generation by jet streams in the troposphere is considered. Evaluations of the energy and pulse of internal gravity waves emitted into the upper atmosphere are given. The obtained values of flows can influence the thermal and dynamic regime of these layers.

Generation and Evolution of Internal Waves in Luzon Strait

DTIC Science & Technology

2015-09-30

1 DISTRIBUTION STATEMENT A. Approved for public release; distribution is unlimited. Generation and Evolution of Internal Waves in Luzon...inertial waves , nonlinear internal waves (NLIWs), and turbulence mixing––in the ocean and thereby help develop improved parameterizations of mixing for...ocean models. Mixing within the stratified ocean is a particular focus as the complex interplay of internal waves from a variety of sources and

Solid–Liquid Phase Change Driven by Internal Heat Generation

DOE Office of Scientific and Technical Information (OSTI.GOV)

John Crepeau; Ali s. Siahpush

2012-07-01

This article presents results of solid-liquid phase change, the Stefan Problem, where melting is driven internal heat generation, in a cylindrical geometry. The comparison between a quasi-static analytical solution for Stefan numbers less than one and numerical solutions shows good agreement. The computational results of phase change with internal heat generation show how convection cells form in the liquid region. A scale analysis of the same problem shows four distinct regions of the melting process.

ISSA/TSS power preliminary design

NASA Technical Reports Server (NTRS)

Main, John A.

1996-01-01

A projected power shortfall during the initial utilization flights of the International Space Station Alpha (ISSA) has prompted an inquiry into the use of the Tethered Satellite System (TSS) to provide station power. The preliminary design of the combined ISSA/TSS system is currently underway in the Preliminary Design Office at the Marshall Space Flight Center. This document focuses on the justification for using a tether system on space station, the physical principles behind such a system, and how it might be operated to best utilize its capabilities. The basic components of a simple DC generator are a magnet of some type and a conductive wire. Moving the wire through the magnetic field causes forces to be applied to the electric charges in the conductor, and thus current is induced to flow. This simple concept is the idea behind generating power with space-borne tether systems. The function of the magnet is performed by the earth's magnetic field, and orbiting a conductive tether about the earth effectively moves the tether through the field.

Understanding the intentional acoustic behavior of humpback whales: a production-based approach.

PubMed

Cazau, Dorian; Adam, Olivier; Laitman, Jeffrey T; Reidenberg, Joy S

2013-09-01

Following a production-based approach, this paper deals with the acoustic behavior of humpback whales. This approach investigates various physical factors, which are either internal (e.g., physiological mechanisms) or external (e.g., environmental constraints) to the respiratory tractus of the whale, for their implications in sound production. This paper aims to describe a functional scenario of this tractus for the generation of vocal sounds. To do so, a division of this tractus into three different configurations is proposed, based on the air recirculation process which determines air sources and laryngeal valves. Then, assuming a vocal function (in sound generation or modification) for several specific anatomical components, an acoustic characterization of each of these configurations is proposed to link different spectral features, namely, fundamental frequencies and formant structures, to specific vocal production mechanisms. A discussion around the question of whether the whale is able to fully exploit the acoustic potential of its respiratory tractus is eventually provided.

Orion Scripted Interface Generator (OrionSIG)

NASA Technical Reports Server (NTRS)

Dooling, Robert J.

2013-01-01

The Orion spacecraft undergoing development at NASA and Lockheed Martin aims to launch the first humans to set foot on asteroids and Mars.' Sensors onboard Orion must transmit back to Earth astronomical amounts of data recording almost everything in 50,231 lb. (22,784 kg)2 of spacecraft, down to the temperatures, voltages, or torsions of even the most minor components. This report introduces the new Orion Scripted Interface Generator (OrionSIG) software created by summer 2013 NASA interns Robert Dooling and Samuel Harris. OrionSIG receives a list of Orion variables and produces a script to graph these measurements regardless of their size or type. The program also accepts many other input options to manipulate displays, such as limits on the graph's range or commands to graph different values in a reverse sawtooth wave. OrionSIG paves the way for monitoring stations on Earth to process, display, and test Orion data much more efficiently, a helpful asset in preparation for Orion's first test mission in 2014. Figure I.

Surfing the Pacific Island chains: linking internal wave energetics to coral reef benthic community patterns.

NASA Astrophysics Data System (ADS)

Painter Jones, Matilda; Green, Mattias; Gove, Jamison; Williams, Gareth

2017-04-01

The ocean is saturated with internal waves at tidal frequency. The energy associated with conversion from barotropic to baroclinic can enhance mixing and upwelling at sites of generation and dissipation, which in turn can drive primary production. Hotspots of internal wave generation are located at sudden changes in topography with the Hawaiian archipelago identified as an area of intense internal wave activity. The role of internal waves as a driver of benthic reef community is unexplored and could be key to coral reefs survival in the unknown future. Using a Pacific wide map of internal wave flux and barotropic-to-baroclinic conversion at an unprecedented 1/30th degree resolution, energy budgets were developed for four islands to evaluate dissipation and generation of internal waves. Spatiotemporal variations in benthic community structure were plotted around each island and related to changes in internal wave energetics using a boosted regression tree. Contrasting spatial patterns and species assemblages were seen around islands with distinct internal wave regimes. The relative importance and influence of internal waves on coral reef ecosystems is evaluated.

Johnson-Cook Strength Model for Automotive Steels

NASA Astrophysics Data System (ADS)

Vedantam, K.

2005-07-01

Over the last few years most automotive companies are engaged in performing simulations of the capability of individual components or entire structure of a motor vehicle to adequately sustain the shock (impacts) and to protect the occupants from injuries during crashes. These simulations require constitutive material models (e.g., Johnson-Cook) of the sheet steel and other components based on the compression/tension data obtained in a series of tests performed at quasi-static (˜1/s) to high strain rates (˜2000/s). One such study is undertaken by the recently formed IISI (International Iron and Steel Institute) in organizing the round robin tests to compare the tensile data generated at our Laboratory at strain rates of ˜1/s, ˜300/s, ˜800/s, and ˜2000/s on two grades of automotive steel (Mild steel and Dual Phase-DP 590) using split Hopkinson bar with those generated at high strain rate testing facilities in Germany and Japan. Our tension data on mild steel (flow stress ˜ 500 MPa) suggest a relatively small strain rate sensitivity of the material. The second steel grade (DP-590) tested exhibits significant strain rate sensitivity in that the flow stress increases from about 700 MPa (at ˜1/s) to 900 MPa (at ˜2000/s). J-C strength model constants (A, B, n, and C) for the two steel grades will be presented.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kreutzbruck, M.; Brackrock, D.; Brekow, G.

Lightweight components are increasingly used in different industrial sectors such as transportation, energy generation and automotive. This growing field includes different types of CFRP-structures, hybrid materials and glued components showing - compared to their pure metallic counterparts- a significant more complicated structure in terms of internal interfaces and anisotropy of material parameters. In this work we present the use of matrix phased array to increase the amount of obtained information to enhance the inspection quality. We used different types of carbon materials such as 6 mm thick uni- and bidirectional prepreg specimens containing impact damages. The latter were introduced withmore » different energy levels ranging from 1.3 to 7.2 J. By scanning a 2.25 MHz matrix array with 6 × 10 elements above the prepreg surface and using different angels of incidence a complete 3D-image was generated which allows the detection of defects as small as 1mm in a depth of 4 mm. A comparison with conventional approaches show that the signal-to-noise ratio can be highly increased. This enables us to visualize the region of damage within the impact zone, clearly showing the cone-like damage distribution along increasing material depth. The detection quality allows the estimation of the opening angles of the cone shaped damage, which can be used for further evaluation and quantitation of energy dependent impact damages.« less

The Leiden Family Lab study on Social Anxiety Disorder: A multiplex, multigenerational family study on neurocognitive endophenotypes.

PubMed

Bas-Hoogendam, Janna Marie; Harrewijn, Anita; Tissier, Renaud L M; van der Molen, Melle J W; van Steenbergen, Henk; van Vliet, Irene M; Reichart, Catrien G; Houwing-Duistermaat, Jeanine J; Slagboom, P Eline; van der Wee, Nic J A; Westenberg, P Michiel

2018-06-01

Social anxiety disorder (SAD) is a serious and prevalent psychiatric condition, with a heritable component. However, little is known about the characteristics that are associated with the genetic component of SAD, the so-called "endophenotypes". These endophenotypes could advance our insight in the genetic susceptibility to SAD, as they are on the pathway from genotype to phenotype. The Leiden Family Lab study on Social Anxiety Disorder (LFLSAD) is the first multiplex, multigenerational study aimed to identify neurocognitive endophenotypes of social anxiety. The LFLSAD is characterized by a multidisciplinary approach and encompasses a variety of measurements, including a clinical interview, functional and structural magnetic resonance imaging and an electroencephalography experiment. Participants are family members from 2 generations, from families genetically enriched for SAD. The sample (n = 132 participants, from 9 families) was characterized by a high prevalence of SAD, in both generations (prevalence (sub)clinical SAD: 38.3%). Furthermore, (sub)clinical SAD was positively related to self-reported social anxiety, fear of negative evaluation, trait anxiety, behavioral inhibition, negative affect, and the level of depressive symptoms. By the multidimensional character of the measurements and thorough characterization of the sample, the LFLSAD offers unique opportunities to investigate candidate neurocognitive endophenotypes of SAD. © 2018 The Authors International Journal of Methods in Psychiatric Research Published by John Wiley & Sons Ltd.

Component Exchange Community: A Model of Utilizing Research Components to Foster International Collaboration

ERIC Educational Resources Information Center

Deng, Yi-Chan; Lin, Taiyu; Kinshuk; Chan, Tak-Wai

2006-01-01

"One-to-one" technology enhanced learning research refers to the design and investigation of learning environments and learning activities where every learner is equipped with at least one portable computing device enabled by wireless capability. G1:1 is an international research community coordinated by a network of laboratories conducting…

Meta-analysis of neuropsychological measures of executive functioning in children and adolescents with high-functioning autism spectrum disorder.

PubMed

Lai, Chun Lun Eric; Lau, Zoe; Lui, Simon S Y; Lok, Eugenia; Tam, Venus; Chan, Quinney; Cheng, Koi Man; Lam, Siu Man; Cheung, Eric F C

2017-05-01

Existing literature on the profile of executive dysfunction in autism spectrum disorder showed inconsistent results. Age, comorbid attention-deficit/hyperactivity disorder (ADHD) and cognitive abilities appeared to play a role in confounding the picture. Previous meta-analyses have focused on a few components of executive functions. This meta-analysis attempted to delineate the profile of deficit in several components of executive functioning in children and adolescents with high-functioning autism spectrum disorder (HFASD). Ninety-eight English published case-control studies comparing children and adolescents with HFASD with typically developing controls using well-known neuropsychological measures to assess executive functions were included. Results showed that children and adolescents with HFASD were moderately impaired in verbal working memory (g = 0.67), spatial working memory (g = 0.58), flexibility (g = 0.59), planning (g = 0.62), and generativity (g = 0.60) except for inhibition (g = 0.41). Subgroup analysis showed that impairments were still significant for flexibility (g = 0.57-0.61), generativity (g = 0.52-0.68), and working memory (g = 0.49-0.56) in a sample of autism spectrum disorder (ASD) subjects without comorbid ADHD or when the cognitive abilities of the ASD group and the control group were comparable. This meta-analysis confirmed the presence of executive dysfunction in children and adolescents with HFASD. These deficits are not solely accounted for by the effect of comorbid ADHD and the general cognitive abilities. Our results support the executive dysfunction hypothesis and contribute to the clinical understanding and possible development of interventions to alleviate these deficits in children and adolescents with HFASD. Autism Res 2017, 10: 911-939. © 2016 International Society for Autism Research, Wiley Periodicals, Inc. © 2016 International Society for Autism Research, Wiley Periodicals, Inc.

An investigation on defect-generation conditions in immersion lithography

NASA Astrophysics Data System (ADS)

Tomita, Tadatoshi; Shimoaoki, Takeshi; Enomoto, Masashi; Kyoda, Hideharu; Kitano, Junichi; Suganaga, Toshifumi

2006-03-01

As a powerful candidate for a lithography technique that can accommodate the scaling-down of semiconductors, 193-nm immersion lithography-which realizes a high numerical aperture (NA) and uses deionized water as the medium between the lens and wafer in the exposure system-has been developing at a rapid pace and has reached the stage of practical application. In regards to defects that are a cause for concern in the case of 193-nm immersion lithography, however, many components are still unclear and many problems remain to be solved. It has been pointed out, for example, that in the case of 193-nm immersion lithography, immersion of the resist film in deionized water during exposure causes infiltration of moisture into the resist film, internal components of the resist dissolve into the deionized water, and residual water generated during exposure affects post-processing. Moreover, to prevent this influence of directly immersing the resist in de-ionized water, application of a protective film is regarded as effective. However, even if such a film is applied, it is still highly likely that the above-mentioned defects will still occur. Accordingly, to reduce these defects, it is essential to identify the typical defects occurring in 193-nm immersion lithography and to understand the condition for generation of defects by using some kinds of protective films and resist materials. Furthermore, from now onwards, with further scaling down of semiconductors, it is important to maintain a clear understanding of the relation between defect-generation conditions and critical dimensions (CD). Aiming to extract typical defects occurring in 193-nm immersion lithography, the authors carried out a comparative study with dry exposure lithography, thereby confirming several typical defects associated with immersion lithography. We then investigated the conditions for generation of defects in the case of some kinds of protective films. In addition to that, by investigating the defect-generation conditions and comparing the classification data between wet and dry exposure, we were able to determine the origin of each particular defect involved in immersion lithography. Furthermore, the comparison of CD for wet and dry processing could indicate the future defectivity levels to be expected with shrinking immersion process critical dimensions.

49 CFR 193.2631 - Internal corrosion control.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 3 2011-10-01 2011-10-01 false Internal corrosion control. 193.2631 Section 193... GAS FACILITIES: FEDERAL SAFETY STANDARDS Maintenance § 193.2631 Internal corrosion control. Each component that is subject to internal corrosive attack must be protected from internal corrosion by— (a...

On reliable time-frequency characterization and delay estimation of stimulus frequency otoacoustic emissions

NASA Astrophysics Data System (ADS)

Biswal, Milan; Mishra, Srikanta

2018-05-01

The limited information on origin and nature of stimulus frequency otoacoustic emissions (SFOAEs) necessitates a thorough reexamination into SFOAE analysis procedures. This will lead to a better understanding of the generation of SFOAEs. The SFOAE response waveform in the time domain can be interpreted as a summation of amplitude modulated and frequency modulated component waveforms. The efficiency of a technique to segregate these components is critical to describe the nature of SFOAEs. Recent advancements in robust time-frequency analysis algorithms have staked claims on the more accurate extraction of these components, from composite signals buried in noise. However, their potential has not been fully explored for SFOAEs analysis. Indifference to distinct information, due to nature of these analysis techniques, may impact the scientific conclusions. This paper attempts to bridge this gap in literature by evaluating the performance of three linear time-frequency analysis algorithms: short-time Fourier transform (STFT), continuous Wavelet transform (CWT), S-transform (ST) and two nonlinear algorithms: Hilbert-Huang Transform (HHT), synchrosqueezed Wavelet transform (SWT). We revisit the extraction of constituent components and estimation of their magnitude and delay, by carefully evaluating the impact of variation in analysis parameters. The performance of HHT and SWT from the perspective of time-frequency filtering and delay estimation were found to be relatively less efficient for analyzing SFOAEs. The intrinsic mode functions of HHT does not completely characterize the reflection components and hence IMF based filtering alone, is not recommended for segregating principal emission from multiple reflection components. We found STFT, WT, and ST to be suitable for canceling multiple internal reflection components with marginal altering in SFOAE.

Motor complications in Parkinson's disease: Striatal molecular and electrophysiological mechanisms of dyskinesias.

PubMed

Picconi, Barbara; Hernández, Ledia F; Obeso, Jose A; Calabresi, Paolo

2017-12-08

Long-term levodopa (l-dopa) treatment in patients with Parkinson´s disease (PD) is associated with the development of motor complications (ie, motor fluctuations and dyskinesias). The principal etiopathogenic factors are the degree of nigro-striatal dopaminergic loss and the duration and dose of l-dopa treatment. In this review article we concentrate on analysis of the mechanisms underlying l-dopa-induced dyskinesias, a phenomenon that causes disability in a proportion of patients and that has not benefited from major therapeutic advances. Thus, we discuss the main neurotransmitters, receptors, and pathways that have been thought to play a role in l-dopa-induced dyskinesias from the perspective of basic neuroscience studies. Some important advances in deciphering the molecular pathways involved in these abnormal movements have occurred in recent years to reveal potential targets that could be used for therapeutic purposes. However, it has not been an easy road because there have been a plethora of components involved in the generation of these undesired movements, even bypassing the traditional and well-accepted dopamine receptor activation, as recently revealed by optogenetics. Here, we attempt to unify the available data with the hope of guiding and fostering future research in the field of striatal activation and abnormal movement generation. © 2017 International Parkinson and Movement Disorder Society. © 2017 International Parkinson and Movement Disorder Society.

Image thumbnails that represent blur and noise.

PubMed

Samadani, Ramin; Mauer, Timothy A; Berfanger, David M; Clark, James H

2010-02-01

The information about the blur and noise of an original image is lost when a standard image thumbnail is generated by filtering and subsampling. Image browsing becomes difficult since the standard thumbnails do not distinguish between high-quality and low-quality originals. In this paper, an efficient algorithm with a blur-generating component and a noise-generating component preserves the local blur and the noise of the originals. The local blur is rapidly estimated using a scale-space expansion of the standard thumbnail and subsequently used to apply a space-varying blur to the thumbnail. The noise is estimated and rendered by using multirate signal transformations that allow most of the processing to occur at the lower spatial sampling rate of the thumbnail. The new thumbnails provide a quick, natural way for users to identify images of good quality. A subjective evaluation shows the new thumbnails are more representative of their originals for blurry images. The noise generating component improves the results for noisy images, but degrades the results for textured images. The blur generating component of the new thumbnails may always be used to advantage. The decision to use the noise generating component of the new thumbnails should be based on testing with the particular image mix expected for the application.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Quigley, Kevin; Chemerisov, Sergey; Tkac, Peter

Through irradiations using our 3 MeV Van de Graaf accelerator, Argonne is testing the radiation stability of components of equipment that are being used to dispense molybdenum solutions for use as feeds to 99mTc generators and in the 99mTc generators themselves. Components have been irradiated by both a direct electron beam and photons generated from a tungsten convertor.

International VLBI Service for Geodesy and Astrometry: 1999 Annual Report

NASA Technical Reports Server (NTRS)

Vandenberg, Nancy R. (Editor)

1999-01-01

This volume of reports is the 1999 Annual Report of the International VLBI Service for Geodesy and Astrometry -IVS. The individual reports were contributed by VLBI groups in the international geodetic community who constitute the components of IVS. The 1999 Annual Report documents the work of the IVS components for the year ending March 1, 1999, the official inauguration date of IVS. As the newest of the space technique services, IVS decided to publish this Annual Report as a reference to our organization and its components. The entire contents of this Annual Report also appear on the IVS website at: http://ivscc.gsfc.nasa.gov/pub/arl999. The IVS 1999 Annual Report will be a valuable reference for information about IVS and its components. This Annual Report will serve as a baseline from which we can measure the anticipated progress of IVS in coming years.

Application to Noninvasive Measurement of Blood Components Based on Infrared Spectroscopy

NASA Astrophysics Data System (ADS)

Tamura, Kazuto; Ishizawa, Hiroaki; Fujita, Keiichi; Kaneko, Wataru; Morikawa, Tomotaka; Toba, Eiji; Kobayashi, Hideo

Recently, lifestyle diseases (diabetics, hyperlipemia etc.) have been steadily increasing, because change of diet, lack of exercise, increase an alcoholic intake, and increase a stress. It is a matter of vital importance to us. About tens of millions of people in Japan have approached the danger of lifestyle diseases. So they have to do a blood test to make sure that they have controlled physical condition themselves. Therefore, they have to measure blood components again and again. So, they are burden too heavy. This paper describes a new noninvasive measurement of blood components based on optical sensing. This uses Fourier transform infrared spectroscopy of attenuated total reflection. In order to study, the influence of individual difference, the internal standard method was introduced. This paper describes the detail of the internal standard method and its effect to the blood components calibration. Significant improvement was obtained by using the internal standard.

Three-dimensional NDE of VHTR core components via simulation-based testing. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Guzina, Bojan; Kunerth, Dennis

2014-09-30

A next generation, simulation-driven-and-enabled testing platform is developed for the 3D detection and characterization of defects and damage in nuclear graphite and composite structures in Very High Temperature Reactors (VHTRs). The proposed work addresses the critical need for the development of high-fidelity Non-Destructive Examination (NDE) technologies for as-manufactured and replaceable in-service VHTR components. Centered around the novel use of elastic (sonic and ultrasonic) waves, this project deploys a robust, non-iterative inverse solution for the 3D defect reconstruction together with a non-contact, laser-based approach to the measurement of experimental waveforms in VHTR core components. In particular, this research (1) deploys three-dimensionalmore » Scanning Laser Doppler Vibrometry (3D SLDV) as a means to accurately and remotely measure 3D displacement waveforms over the accessible surface of a VHTR core component excited by mechanical vibratory source; (2) implements a powerful new inverse technique, based on the concept of Topological Sensitivity (TS), for non-iterative elastic waveform tomography of internal defects - that permits robust 3D detection, reconstruction and characterization of discrete damage (e.g. holes and fractures) in nuclear graphite from limited-aperture NDE measurements; (3) implements state-of-the art computational (finite element) model that caters for accurately simulating elastic wave propagation in 3D blocks of nuclear graphite; (4) integrates the SLDV testing methodology with the TS imaging algorithm into a non-contact, high-fidelity NDE platform for the 3D reconstruction and characterization of defects and damage in VHTR core components; and (5) applies the proposed methodology to VHTR core component samples (both two- and three-dimensional) with a priori induced, discrete damage in the form of holes and fractures. Overall, the newly established SLDV-TS testing platform represents a next-generation NDE tool that surpasses all existing techniques for the 3D ultrasonic imaging of material damage from non-contact, limited-aperture waveform measurements. Outlook. The next stage in the development of this technology includes items such as (a) non-contact generation of mechanical vibrations in VHTR components via thermal expansion created by high-intensity laser; (b) development and incorporation of Synthetic Aperture Focusing Technique (SAFT) for elevating the accuracy of 3D imaging in highly noisy environments with minimal accessible surface; (c) further analytical and computational developments to facilitate the reconstruction of diffuse damage (e.g. microcracks) in nuclear graphite as they lead to the dispersion of elastic waves, (d) concept of model updating for accurate tracking of the evolution of material damage via periodic inspections; (d) adoption of the Bayesian framework to obtain information on the certainty of obtained images; and (e) optimization of the computational scheme toward real-time, model-based imaging of damage in VHTR core components.« less

Connector tube for a turbine rotor cooling circuit

DOEpatents

Li, Ming Cheng

2003-06-24

A tubular connector adapted to extend between two tubular components comprising a tubular body having an internal diameter, a first free end including an annular radial flange having a tapered surface adapted to engage a complementary seating surface on a first of the two tubular components, the internal diameter remaining constant through the first free end; and a second free end having an annular bulbous shape adapted to seat within a cylindrical end of a second of the two tubular components.

Connector tube for a turbine rotor cooling circuit

DOEpatents

Li, Ming Cheng

2002-01-01

A tubular connector adapted to extend between two tubular components comprising a tubular body having an internal diameter, a first free end including an annular radial flange having a tapered surface adapted to engage a complementary seating surface on a first of the two tubular components, the internal diameter remaining constant through the first free end; and a second free end having an annular bulbous shape adapted to seat within a cylindrical end of a second of the two tubular components.

Shuttle filter study. Volume 2: Contaminant generation and sensitivity studies

NASA Technical Reports Server (NTRS)

1974-01-01

Contaminant generation studies were conducted at the component level using two different methods, radioactive tracer technique and gravimetric analysis test procedure. Both of these were reduced to practice during this program. In the first of these methods, radioactively tagged components typical of those used in spacecraft were studied to determine their contaminant generation characteristics under simulated operating conditions. Because the purpose of the work was: (1) to determine the types and quantities of contaminants generated; and (2) to evaluate improved monitoring and detection schemes, no attempt was made to evaluate or qualify specific components. The components used in this test program were therefore not flight hardware items. Some of them had been used in previous tests; some were obsolete; one was an experimental device. In addition to the component tests, various materials of interest to contaminant and filtration studies were irradiated and evaluated for use as autotracer materials. These included test dusts, plastics, valve seat materials, and bearing cage materials.

Power Take-off System for Marine Renewable Devices, CRADA Number CRD-14-566

DOE Office of Scientific and Technical Information (OSTI.GOV)

Muljadi, Eduard

Ocean Renewable Power Company (ORPC) proposes a project to develop and test innovative second-generation power take-off (PTO) components for the U.S. Department of Energy's 2013 FOA: Marine and Hydrokinetic System Performance Advancement, Topic Area 2 (Project). Innovative PTO components will include new and improved designs for bearings, couplings and a subsea electrical generator. Specific project objectives include the following: (1) Develop components for an advanced PTO suitable for MHK devices; (2) Bench test these components; (3) Assess the component and system performance benefits; (4) Perform a system integration study to integrate these components into an ORPC hydrokinetic turbine. National Renewablemore » Energy Laboratory (NREL) will participate on the ORPC lead team to review design of the generator and will provide guidance on the design. Based on inputs from the project team, NREL will also provide an economic analysis of the impacts of the proposed system performance advancements.« less

International CPR guidelines - perspectives in CPR.

PubMed

Nolan, Jerry P

2013-09-01

The International Liaison Committee on Resuscitation (ILCOR) co-ordinates regular reviews of cardiopulmonary resuscitation (CPR) science and publishes consensus on science statements and treatment recommendations. These outputs are used by international resuscitation organisations to generate clinical guidelines. This review will outline the history behind the development of international CPR guidelines and will provide a detailed description of the current guideline generating process. A perspective is provided on the future of this process and the prospects for completely unified international CPR guidelines. Copyright © 2013 Elsevier Ltd. All rights reserved.

Selected papers from the 7th IEEE International Nanoelectronics Conference (INEC 2016) and the 5th International Symposium on Next-Generation Electronics (ISNE 2016)

NASA Astrophysics Data System (ADS)

Kok, Chi-Wah; Tam, Wing-Shan

2017-12-01

May is a busy but fruitful month of the year 2016, in which two renowned international conferences, the 7th IEEE International Nanoelectronics Conference (INEC 2016) and the 5th International Symposium on Next Generation Electronics (ISNE 2016), were successfully held in the technology hubs of Chengdu China and Hsinchu Taiwan, respectively. This special issue is a collection of selected research papers presented in these two conferences.

Internal Tide Generation by Steep Topography

DTIC Science & Technology

2007-09-01

acting on the barotropic tide ( Foda and Hill 1998) was incomplete. Kunze will put this work in the context of recent internal tide research and...Topographically generated internal waves in the open ocean. J. Geophys. Res., 80, 320-327. Foda , M.A., and D.F. Hill, 1998: Nonlinear energy...Bispectral analysis of energy transfer within the two-dimensional ocean internal wave field. . Phys. Oceanogr., 35, 2104-2109. Garrett, C., and E

Digital time delay

DOEpatents

Martin, A.D.

1986-05-09

Method and apparatus are provided for generating an output pulse following a trigger pulse at a time delay interval preset with a resolution which is high relative to a low resolution available from supplied clock pulses. A first lumped constant delay provides a first output signal at predetermined interpolation intervals corresponding to the desired high resolution time interval. Latching circuits latch the high resolution data to form a first synchronizing data set. A selected time interval has been preset to internal counters and corrected for circuit propagation delay times having the same order of magnitude as the desired high resolution. Internal system clock pulses count down the counters to generate an internal pulse delayed by an internal which is functionally related to the preset time interval. A second LCD corrects the internal signal with the high resolution time delay. A second internal pulse is then applied to a third LCD to generate a second set of synchronizing data which is complementary with the first set of synchronizing data for presentation to logic circuits. The logic circuits further delay the internal output signal with the internal pulses. The final delayed output signal thereafter enables the output pulse generator to produce the desired output pulse at the preset time delay interval following input of the trigger pulse.

Triangle Geometry Processing for Surface Modeling and Cartesian Grid Generation

NASA Technical Reports Server (NTRS)

Aftosmis, Michael J. (Inventor); Melton, John E. (Inventor); Berger, Marsha J. (Inventor)

2002-01-01

Cartesian mesh generation is accomplished for component based geometries, by intersecting components subject to mesh generation to extract wetted surfaces with a geometry engine using adaptive precision arithmetic in a system which automatically breaks ties with respect to geometric degeneracies. During volume mesh generation, intersected surface triangulations are received to enable mesh generation with cell division of an initially coarse grid. The hexagonal cells are resolved, preserving the ability to directionally divide cells which are locally well aligned.

Triangle geometry processing for surface modeling and cartesian grid generation

DOEpatents

Aftosmis, Michael J [San Mateo, CA; Melton, John E [Hollister, CA; Berger, Marsha J [New York, NY

2002-09-03

Cartesian mesh generation is accomplished for component based geometries, by intersecting components subject to mesh generation to extract wetted surfaces with a geometry engine using adaptive precision arithmetic in a system which automatically breaks ties with respect to geometric degeneracies. During volume mesh generation, intersected surface triangulations are received to enable mesh generation with cell division of an initially coarse grid. The hexagonal cells are resolved, preserving the ability to directionally divide cells which are locally well aligned.

Quantification of the internal resistance distribution of microbial fuel cells.

PubMed

Fan, Yanzhen; Sharbrough, Evan; Liu, Hong

2008-11-01

Identifying the limiting factors in a microbial fuel cell (MFC) system requires qualifying the contribution of each component of an MFC to internal resistance. In this study, a new method was developed to calculate the internal resistance distribution of an MFC. Experiments were conducted to identify the limiting factors in single-chamber MFCs by varying the anode surface areas, cathode surface areas, and phosphate buffer concentrations. For the MFCs with equally sized electrodes (7 cm2) and 200 mM phosphate buffer, the anode contributed just 5.4% of the internal resistance, while the cathode and the electrolyte each contributed 47.3%, indicating that the anode was not the limiting factor in power generation. The limitation of the cathode was further revealed by the 780% higher area-specific resistance (284.4 omega cm2) than the 32.3 omega cm2 of the anode. The electrolyte limitation was also evidenced by the greatly increased contribution of electrolyte in internal resistance from 47.3 to 78.2% when the concentration of phosphate buffer was decreased from 200 to 50 mM. An anodic power density of 6860 mW/m2 was achieved at a current density of 2.62 mA/cm2 using the MFCs with an anode/cathode area ratio of 1/14 and 200 mM phosphate buffer. The method was also successfully applied to analyze the internal resistance distribution of the two chamber MFCs from a previously reported study. The comparison of the internal resistances of the two air cathode systems indicates that the much lower resistances, including anode, cathode, and membrane resistances, contributed to the much better performance of the single-chamber MFCs than the two-chamber system.

Generating Models of Infinite-State Communication Protocols Using Regular Inference with Abstraction

NASA Astrophysics Data System (ADS)

Aarts, Fides; Jonsson, Bengt; Uijen, Johan

In order to facilitate model-based verification and validation, effort is underway to develop techniques for generating models of communication system components from observations of their external behavior. Most previous such work has employed regular inference techniques which generate modest-size finite-state models. They typically suppress parameters of messages, although these have a significant impact on control flow in many communication protocols. We present a framework, which adapts regular inference to include data parameters in messages and states for generating components with large or infinite message alphabets. A main idea is to adapt the framework of predicate abstraction, successfully used in formal verification. Since we are in a black-box setting, the abstraction must be supplied externally, using information about how the component manages data parameters. We have implemented our techniques by connecting the LearnLib tool for regular inference with the protocol simulator ns-2, and generated a model of the SIP component as implemented in ns-2.

Internal wave mode resonant triads in an arbitrarly stratified finite-depth ocean with background rotation

NASA Astrophysics Data System (ADS)

Varma, Dheeraj; Mathur, Manikandan

2017-11-01

Internal tides generated by barotropic tides on bottom topography or the spatially compact near-inertial mixed layer currents excited by surface winds can be conveniently represented in the linear regime as a superposition of vertical modes at a given frequency in an arbitrarily stratified ocean of finite depth. Considering modes (m , n) at a frequency ω in the primary wave field, we derive the weakly nonlinear solution, which contains a secondary wave at 2 ω that diverges when it forms a resonant triad with the primary waves. In nonuniform stratifications, resonant triads are shown to occur when the horizontal component of the classical RTI criterion k->1 +k->2 +k->3 = 0 is satisfied along with a non-orthogonality criterion. In nonuniform stratifications with a pycnocline, infinitely more pairs of primary wave modes (m , n) result in RTI when compared to a uniform stratification. Further, two nearby high modes at around the near-inertial frequency often form a resonant triad with a low mode at 2 ω , reminiscent of the features of PSI near the critical latitude. The theoretical framework is then adapted to investigate RTI in two different scenarios: low-mode internal tide scattering over topography, and internal wave beams incident on a pycnocline. The authors thank the Ministry of Earth Sciences, Government of India for financial support under the Monsoon Mission Grant MM/2014/IND-002.

Fast and simple high-capacity quantum cryptography with error detection

PubMed Central

Lai, Hong; Luo, Ming-Xing; Pieprzyk, Josef; Zhang, Jun; Pan, Lei; Li, Shudong; Orgun, Mehmet A.

2017-01-01

Quantum cryptography is commonly used to generate fresh secure keys with quantum signal transmission for instant use between two parties. However, research shows that the relatively low key generation rate hinders its practical use where a symmetric cryptography component consumes the shared key. That is, the security of the symmetric cryptography demands frequent rate of key updates, which leads to a higher consumption of the internal one-time-pad communication bandwidth, since it requires the length of the key to be as long as that of the secret. In order to alleviate these issues, we develop a matrix algorithm for fast and simple high-capacity quantum cryptography. Our scheme can achieve secure private communication with fresh keys generated from Fibonacci- and Lucas- valued orbital angular momentum (OAM) states for the seed to construct recursive Fibonacci and Lucas matrices. Moreover, the proposed matrix algorithm for quantum cryptography can ultimately be simplified to matrix multiplication, which is implemented and optimized in modern computers. Most importantly, considerably information capacity can be improved effectively and efficiently by the recursive property of Fibonacci and Lucas matrices, thereby avoiding the restriction of physical conditions, such as the communication bandwidth. PMID:28406240

Fast and simple high-capacity quantum cryptography with error detection.

PubMed

Lai, Hong; Luo, Ming-Xing; Pieprzyk, Josef; Zhang, Jun; Pan, Lei; Li, Shudong; Orgun, Mehmet A

2017-04-13

Quantum cryptography is commonly used to generate fresh secure keys with quantum signal transmission for instant use between two parties. However, research shows that the relatively low key generation rate hinders its practical use where a symmetric cryptography component consumes the shared key. That is, the security of the symmetric cryptography demands frequent rate of key updates, which leads to a higher consumption of the internal one-time-pad communication bandwidth, since it requires the length of the key to be as long as that of the secret. In order to alleviate these issues, we develop a matrix algorithm for fast and simple high-capacity quantum cryptography. Our scheme can achieve secure private communication with fresh keys generated from Fibonacci- and Lucas- valued orbital angular momentum (OAM) states for the seed to construct recursive Fibonacci and Lucas matrices. Moreover, the proposed matrix algorithm for quantum cryptography can ultimately be simplified to matrix multiplication, which is implemented and optimized in modern computers. Most importantly, considerably information capacity can be improved effectively and efficiently by the recursive property of Fibonacci and Lucas matrices, thereby avoiding the restriction of physical conditions, such as the communication bandwidth.

Recovering metallic fractions from waste electrical and electronic equipment by a novel vibration system.

PubMed

Habib, Muddasar; Miles, Nicholas J; Hall, Philip

2013-03-01

The need to recover and recycle valuable resources from Waste Electrical and Electronic Equipment (WEEE) is of growing importance as increasing amounts are generated due to shorter product life cycles, market expansions, new product developments and, higher consumption and production rates. The European Commission (EC) directive, 2002/96/EC, on WEEE became law in UK in January 2007 setting targets to recover up to 80% of all WEEE generated. Printed Wire Board (PWB) and/or Printed Circuit Board (PCB) is an important component of WEEE with an ever increasing tonnage being generated. However, the lack of an accurate estimate for PCB production, future supply and uncertain demands of its recycled materials in international markets has provided the motivation to explore different approaches to recycle PCBs. The work contained in this paper focuses on a novel, dry separation methodology in which vertical vibration is used to separate the metallic and non-metallic fractions of PCBs. When PCBs were comminuted to less than 1mm in size, metallic grades as high as 95% (measured by heavy liquid analysis) could be achieved in the recovered products. Copyright © 2012 Elsevier Ltd. All rights reserved.

Fast and simple high-capacity quantum cryptography with error detection

NASA Astrophysics Data System (ADS)

Lai, Hong; Luo, Ming-Xing; Pieprzyk, Josef; Zhang, Jun; Pan, Lei; Li, Shudong; Orgun, Mehmet A.

2017-04-01

Quantum cryptography is commonly used to generate fresh secure keys with quantum signal transmission for instant use between two parties. However, research shows that the relatively low key generation rate hinders its practical use where a symmetric cryptography component consumes the shared key. That is, the security of the symmetric cryptography demands frequent rate of key updates, which leads to a higher consumption of the internal one-time-pad communication bandwidth, since it requires the length of the key to be as long as that of the secret. In order to alleviate these issues, we develop a matrix algorithm for fast and simple high-capacity quantum cryptography. Our scheme can achieve secure private communication with fresh keys generated from Fibonacci- and Lucas- valued orbital angular momentum (OAM) states for the seed to construct recursive Fibonacci and Lucas matrices. Moreover, the proposed matrix algorithm for quantum cryptography can ultimately be simplified to matrix multiplication, which is implemented and optimized in modern computers. Most importantly, considerably information capacity can be improved effectively and efficiently by the recursive property of Fibonacci and Lucas matrices, thereby avoiding the restriction of physical conditions, such as the communication bandwidth.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hoekman, S. Kent; Broch, Broch; Robbins, Curtis

The primary objective of this project was to utilize a flexible, energy-efficient facility, called the DRI Renewable Energy Experimental Facility (REEF) to support various renewable energy research and development (R&D) efforts, along with education and outreach activities. The REEF itself consists of two separate buildings: (1) a 1200-ft2 off-grid capable house and (2) a 600-ft2 workshop/garage to support larger-scale experimental work. Numerous enhancements were made to DRI's existing renewable power generation systems, and several additional components were incorporated to support operation of the REEF House. The power demands of this house are satisfied by integrating and controlling PV arrays, solarmore » thermal systems, wind turbines, an electrolyzer for renewable hydrogen production, a gaseous-fuel internal combustion engine/generator set, and other components. Cooling needs of the REEF House are satisfied by an absorption chiller, driven by solar thermal collectors. The REEF Workshop includes a unique, solar air collector system that is integrated into the roof structure. This system provides space heating inside the Workshop, as well as a hot water supply. The Workshop houses a custom-designed process development unit (PDU) that is used to convert woody biomass into a friable, hydrophobic char that has physical and chemical properties similar to low grade coal. Besides providing sufficient space for operation of this PDU, the REEF Workshop supplies hot water that is used in the biomass treatment process. The DRI-REEF serves as a working laboratory for evaluating and optimizing the performance of renewable energy components within an integrated, residential-like setting. The modular nature of the system allows for exploring alternative configurations and control strategies. This experimental test bed is also highly valuable as an education and outreach tool both in providing an infrastructure for student research projects, and in highlighting renewable energy features to the public.« less

D-Optimal mixture experimental design for stealth biodegradable crosslinked docetaxel-loaded poly-ε-caprolactone nanoparticles manufactured by dispersion polymerization.

PubMed

Ogunwuyi, O; Adesina, S; Akala, E O

2015-03-01

We report here our efforts on the development of stealth biodegradable crosslinked poly-ε-caprolactone nanoparticles by free radical dispersion polymerization suitable for the delivery of bioactive agents. The uniqueness of the dispersion polymerization technique is that it is surfactant free, thereby obviating the problems known to be associated with the use of surfactants in the fabrication of nanoparticles for biomedical applications. Aided by a statistical software for experimental design and analysis, we used D-optimal mixture statistical experimental design to generate thirty batches of nanoparticles prepared by varying the proportion of the components (poly-ε-caprolactone macromonomer, crosslinker, initiators and stabilizer) in acetone/water system. Morphology of the nanoparticles was examined using scanning electron microscopy (SEM). Particle size and zeta potential were measured by dynamic light scattering (DLS). Scheffe polynomial models were generated to predict particle size (nm) and particle surface zeta potential (mV) as functions of the proportion of the components. Solutions were returned from simultaneous optimization of the response variables for component combinations to (a) minimize nanoparticle size (small nanoparticles are internalized into disease organs easily, avoid reticuloendothelial clearance and lung filtration) and (b) maximization of the negative zeta potential values, as it is known that, following injection into the blood stream, nanoparticles with a positive zeta potential pose a threat of causing transient embolism and rapid clearance compared to negatively charged particles. In vitro availability isotherms show that the nanoparticles sustained the release of docetaxel for 72 to 120 hours depending on the formulation. The data show that nanotechnology platforms for controlled delivery of bioactive agents can be developed based on the nanoparticles.

Electrogenic steps of light-driven proton transport in ESR, a retinal protein from Exiguobacterium sibiricum.

PubMed

Siletsky, Sergey A; Mamedov, Mahir D; Lukashev, Evgeniy P; Balashov, Sergei P; Dolgikh, Dmitriy A; Rubin, Andrei B; Kirpichnikov, Mikhail P; Petrovskaya, Lada E

2016-11-01

A retinal protein from Exiguobacterium sibiricum (ESR) functions as a light-driven proton pump. Unlike other proton pumps, it contains Lys96 instead of a usual carboxylic residue in the internal proton donor site. Nevertheless, the reprotonation of the Schiff base occurs fast, indicating that Lys96 facilitates proton transfer from the bulk. In this study we examined kinetics of light-induced transmembrane electrical potential difference, ΔΨ, generated in proteoliposomes reconstituted with ESR. We show that total magnitude of ΔΨ is comparable to that produced by bacteriorhodopsin but its kinetic components and their pH dependence are substantially different. The results are in agreement with the earlier finding that proton uptake precedes reprotonation of the Schiff base in ESR, suggesting that Lys96 is unprotonated in the initial state and gains a proton transiently in the photocycle. The electrogenic phases and the photocycle transitions related to proton transfer from the bulk to the Schiff base are pH dependent. At neutral pH, they occur with τ 0.5ms and 4.5ms. At alkaline pH, the fast component ceases and Schiff base reprotonation slows. At pH8.4, a spectrally silent electrogenic component with τ 0.25ms is detected, which can be attributed to proton transfer from the bulk to Lys96. At pH5.1, the amplitude of ΔΨ decreases 10 fold, reflecting a decreased yield and rate of proton transfer, apparently from protonation of the acceptor (Asp85-His57 pair) in the initial state. The features of the photoelectric potential generation correlate with the ESR structure and proposed mechanism of proton transfer. Copyright © 2016 Elsevier B.V. All rights reserved.

A comparison of self-generated versus taught internal strategies for working memory.

PubMed

Dirette, Diane Powers

2015-01-01

Internal strategies are effective for improving working memory. These internal working memory strategies can be taught or self-generated. This study compares working memory performance using taught versus self-generated internal working memory strategies and explores the quantity, type and carry-over of the use of these strategies. An experimental cohort design with randomly assigned groups compared the performances among 120 participants on 5 memory tests given prior, immediately following and at 1 month post intervention. There were no significant differences in the number or type of internal memory strategies used by the groups with chunking, repetition and association used most commonly. The group that self-generated strategies performed significantly better on a contextual memory test and the group that was taught strategies performed better on a face/name recall test for which a specific strategy was taught. The group that was taught strategies performed significantly worse on contextual memory tests from pre-test to follow-up. Participants who generated their own strategies or used a specific strategy for a specific task did as well as participants who were taught myriad internal WM strategies. Teaching too many strategies may overwhelm participants or may distract them from using the context that is available in such tasks.

Anatomic suitability of aortoiliac aneurysms for next generation branched systems.

PubMed

Pearce, Benjamin J; Varu, Vinit N; Glocker, Roan; Novak, Zdenek; Jordan, William D; Lee, Jason T

2015-01-01

Preservation of internal iliac flow is an important consideration to prevent ischemic complications during endovascular aneurysm repair. We sought to determine the suitability of aortoiliac aneurysms for off-the-shelf iliac branched systems currently in clinical trial. Patients undergoing abdominal aortic aneurysm repair from 2004 to 2013 at 2 institutions were reviewed. Centerline diameters and lengths of aortoiliac morphology were measured using three-dimensional workstations and compared with inclusion/exclusion criteria for both Cook and Gore iliac branch devices. Of the nearly 2,400 aneurysm repairs performed during the study period, 99 patients had common iliac aneurysms suitable for imaging review. Eighteen of the 99 (18.2%) patients and 25/99 (25.3%) patients fit the inclusion criteria and would have been able to be treated using the Cook and Gore iliac branch devices, respectively. The most common reason for exclusion from Cook was internal iliac diameter of <6 or >9 mm (68/99, 68.7%). The most common reason for exclusion from Gore was proximal common iliac diameter of <17 mm (39/99, 39.4%) and inadequate internal iliac artery diameter of <6.5 or >13.5 mm (37/99, 37.3%). Comparing the included patients across both devices, a total of 35/99 (35.4%) of patients would be eligible for the treatment of aortoiliac aneurysms based on anatomic criteria. Only 35% of the aneurysm repairs involving common iliac arteries would have been candidates for the 2 iliac branch devices currently in trial based on anatomic criteria. The major common reason for exclusion is the internal iliac landing zone for both devices. Design modifications for future generation iliac branch technology should focus on diameter accommodations for the hypogastric branch stent and proximal and distal sizes of the iliac branch components. Familiarity with alternate branch preserving techniques is still needed in the majority of cases. Copyright © 2015 Elsevier Inc. All rights reserved.

26 CFR 1.1563-1 - Definition of controlled group of corporations and component members and related concepts.

Code of Federal Regulations, 2010 CFR

2010-04-01

... and component members and related concepts. 1.1563-1 Section 1.1563-1 Internal Revenue INTERNAL... related concepts. (a) Controlled group of corporations—(1) In general—(i) Types of controlled groups. For...) Additional concepts used in applying the controlled group rules. (A) The term testing date means the date...

International VLBI Service for Geodesy and Astrometry 2013 Annual Report

NASA Technical Reports Server (NTRS)

Baver, Karen D.; Behrend, Dirk; Armstrong, Kyla L.

2014-01-01

This volume of reports is the 2013 Annual Report of the International VLBI Service for Geodesy and Astrometry (IVS). The individual reports were contributed by VLBI groups in the international geodetic and astrometric community who constitute the permanent components of IVS. The IVS 2013 Annual Report documents the work of the IVS components for the calendar year 2013, our fifteenth year of existence. The reports describe changes, activities, and progress of the IVS. Many thanks to all IVS components who contributed to this Annual Report. With the exception of the first section and the last section, the contents of this Annual Report also appear on the IVS Web site at http://ivscc.gsfc.nasa.gov/publications/ar2013.

International VLBI Service for Geodesy and Astrometry 2012 Annual Report

NASA Technical Reports Server (NTRS)

Baver, Karen D.; Behrend, Dirk; Armstrong, Kyla L.

2013-01-01

This volume of reports is the 2012 Annual Report of the International VLBI Service for Geodesy and Astrometry (IVS). The individual reports were contributed by VLBI groups in the international geodetic and astrometric community who constitute the permanent components of IVS. The IVS 2012 Annual Report documents the work of the IVS components for the calendar year 2012, our fourteenth year of existence. The reports describe changes, activities, and progress ofthe IVS. Many thanks to all IVS components who contributed to this Annual Report. With the exception of the first section and parts of the last section (described below), the contents of this Annual Report also appear on the IVS Web site athttp:ivscc.gsfc.nasa.gov/publications/ar2012

Spontaneous generation and reversals of mean flows in a convectively-generated internal gravity wave field

NASA Astrophysics Data System (ADS)

Couston, Louis-Alexandre; Lecoanet, Daniel; Favier, Benjamin; Le Bars, Michael

2017-11-01

We investigate via direct numerical simulations the spontaneous generation and reversals of mean zonal flows in a stably-stratified fluid layer lying above a turbulent convective fluid. Contrary to the leading idealized theories of mean flow generation by self-interacting internal waves, the emergence of a mean flow in a convectively-generated internal gravity wave field is not always possible because nonlinear interactions of waves of different frequencies can disrupt the mean flow generation mechanism. Strong mean flows thus emerge when the divergence of the Reynolds stress resulting from the nonlinear interactions of internal waves produces a strong enough anti-diffusive acceleration for the mean flow, which, as we will demonstrate, is the case when the Prandtl number is sufficiently low, or when the energy input into the internal wavefield by the convection and density stratification are sufficiently large. Implications for mean zonal flow production as observed in the equatorial stratospheres of the Earth, Saturn and Jupiter, and possibly occurring in other geophysical systems such as planetary and stellar interiors will be briefly discussed. Funding provided by the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation program through Grant Agreement No. 681835-FLUDYCO-ERC-2015-CoG.

Internal Wave Generation by Convection

NASA Astrophysics Data System (ADS)

Lecoanet, Daniel Michael

In nature, it is not unusual to find stably stratified fluid adjacent to convectively unstable fluid. This can occur in the Earth's atmosphere, where the troposphere is convective and the stratosphere is stably stratified; in lakes, where surface solar heating can drive convection above stably stratified fresh water; in the oceans, where geothermal heating can drive convection near the ocean floor, but the water above is stably stratified due to salinity gradients; possible in the Earth's liquid core, where gradients in thermal conductivity and composition diffusivities maybe lead to different layers of stable or unstable liquid metal; and, in stars, as most stars contain at least one convective and at least one radiative (stably stratified) zone. Internal waves propagate in stably stratified fluids. The characterization of the internal waves generated by convection is an open problem in geophysical and astrophysical fluid dynamics. Internal waves can play a dynamically important role via nonlocal transport. Momentum transport by convectively excited internal waves is thought to generate the quasi-biennial oscillation of zonal wind in the equatorial stratosphere, an important physical phenomenon used to calibrate global climate models. Angular momentum transport by convectively excited internal waves may play a crucial role in setting the initial rotation rates of neutron stars. In the last year of life of a massive star, convectively excited internal waves may transport even energy to the surface layers to unbind them, launching a wind. In each of these cases, internal waves are able to transport some quantity--momentum, angular momentum, energy--across large, stable buoyancy gradients. Thus, internal waves represent an important, if unusual, transport mechanism. This thesis advances our understanding of internal wave generation by convection. Chapter 2 provides an underlying theoretical framework to study this problem. It describes a detailed calculation of the internal gravity wave spectrum, using the Lighthill theory of wave excitation by turbulence. We use a Green's function approach, in which we convolve a convective source term with the Green's function of different internal gravity waves. The remainder of the thesis is a circuitous attempt to verify these analytical predictions. I test the predictions of Chapter 2 via numerical simulation. The first step is to identify a code suitable for this study. I helped develop the Dedalus code framework to study internal wave generation by convection. Dedalus can solve many different partial differential equations using the pseudo-spectral numerical method. In Chapter 3, I demonstrate Dedalus' ability to solve different equations used to model convection in astrophysics. I consider both the propagation and damping of internal waves, and the properties of low Rayleigh number convective steady states, in six different equation sets used in the astrophysics literature. This shows that Dedalus can be used to solve the equations of interest. Next, in Chapter 4, I verify the high accuracy of Dedalus by comparing it to the popular astrophysics code Athena in a standard Kelvin-Helmholtz instability test problem. Dedalus performs admirably in comparison to Athena, and provides a high standard for other codes solving the fully compressible Navier-Stokes equations. Chapter 5 demonstrates that Dedalus can simulate convective adjacent to a stably stratified region, by studying convective mixing near carbon flames. The convective overshoot and mixing is well-resolved, and is able to generate internal waves. Confident in Dedalus' ability to study the problem at hand, Chapter 6 describes simulations inspired by water experiments of internal wave generation by convection. The experiments exploit water's unusual property that its density maximum is at 4°C, rather than at 0°C. We use a similar equation of state in Dedalus, and study internal gravity waves generation by convection in a water-like fluid. We test two models of wave generation: bulk excitation (equivalent to the Lighthill theory described in Chapter 2), and surface excitation. We find the bulk excitation model accurately reproduces the waves generated in the simulations, validating the calculations of Chapter 2.

European validation of The Comprehensive International Classification of Functioning, Disability and Health Core Set for Osteoarthritis from the perspective of patients with osteoarthritis of the knee or hip.

PubMed

Weigl, Martin; Wild, Heike

2017-09-15

To validate the International Classification of Functioning, Disability and Health Comprehensive Core Set for Osteoarthritis from the patient perspective in Europe. This multicenter cross-sectional study involved 375 patients with knee or hip osteoarthritis. Trained health professionals completed the Comprehensive Core Set, and patients completed the Short-Form 36 questionnaire. Content validity was evaluated by calculating prevalences of impairments in body function and structures, limitations in activities and participation and environmental factors, which were either barriers or facilitators. Convergent construct validity was evaluated by correlating the International Classification of Functioning, Disability and Health categories with the Short-Form 36 Physical Component Score and the SF-36 Mental Component Score in a subgroup of 259 patients. The prevalences of all body function, body structure and activities and participation categories were >40%, >32% and >20%, respectively, and all environmental factors were relevant for >16% of patients. Few categories showed relevant differences between knee and hip osteoarthritis. All body function categories and all but two activities and participation categories showed significant correlations with the Physical Component Score. Body functions from the ICF chapter Mental Functions showed higher correlations with the Mental Component Score than with the Physical Component Score. This study supports the validity of the International Classification of Functioning, Disability and Health Comprehensive Core Set for Osteoarthritis. Implications for Rehabilitation Comprehensive International Classification of Functioning, Disability and Health Core Sets were developed as practical tools for application in multidisciplinary assessments. The validity of the Comprehensive International Classification of Functioning, Disability and Health Core Set for Osteoarthritis in this study supports its application in European patients with osteoarthritis. The differences in results between this Europe validation study and a previous Singaporean validation study underscore the need to validate the International Classification of Functioning, Disability and Health Core Sets in different regions of the world.

Developed-developing country partnerships: Benefits to developed countries?

PubMed Central

2012-01-01

Developing countries can generate effective solutions for today’s global health challenges. This paper reviews relevant literature to construct the case for international cooperation, and in particular, developed-developing country partnerships. Standard database and web-based searches were conducted for publications in English between 1990 and 2010. Studies containing full or partial data relating to international cooperation between developed and developing countries were retained for further analysis. Of 227 articles retained through initial screening, 65 were included in the final analysis. The results were two-fold: some articles pointed to intangible benefits accrued by developed country partners, but the majority of information pointed to developing country innovations that can potentially inform health systems in developed countries. This information spanned all six WHO health system components. Ten key health areas where developed countries have the most to learn from the developing world were identified and include, rural health service delivery; skills substitution; decentralisation of management; creative problem-solving; education in communicable disease control; innovation in mobile phone use; low technology simulation training; local product manufacture; health financing; and social entrepreneurship. While there are no guarantees that innovations from developing country experiences can effectively transfer to developed countries, combined developed-developing country learning processes can potentially generate effective solutions for global health systems. However, the global pool of knowledge in this area is virgin and further work needs to be undertaken to advance understanding of health innovation diffusion. Even more urgently, a standardized method for reporting partnership benefits is needed—this is perhaps the single most immediate need in planning for, and realizing, the full potential of international cooperation between developed and developing countries. PMID:22709651

Synaptically activated Ca2+ waves in layer 2/3 and layer 5 rat neocortical pyramidal neurons

PubMed Central

Larkum, Matthew E; Watanabe, Shigeo; Nakamura, Takeshi; Lasser-Ross, Nechama; Ross, William N

2003-01-01

Calcium waves in layer 2/3 and layer 5 neocortical somatosensory pyramidal neurons were examined in slices from 2- to 8-week-old rats. Repetitive synaptic stimulation evoked a delayed, all-or-none [Ca2+]i increase primarily on the main dendritic shaft. This component was blocked by 1 mm (R,S)-α-methyl-4-carboxyphenylglycine (MCPG), 10 μm ryanodine, 1 mg ml−1 internal heparin, and was not blocked by 400 μm internal Ruthenium Red, indicating that it was due to Ca2+ release from internal stores by inositol 1,4,5-trisphosphate (IP3) mobilized via activation of metabotropic glutamate receptors. Calcium waves were initiated on the apical shaft at sites between the soma to around the main branch point, mostly at insertion points of oblique dendrites, and spread in both directions along the shaft. In the proximal dendrites the peak amplitude of the resulting [Ca2+]i change was much larger than that evoked by a train of Na+ spikes. In distal dendrites the peak amplitude was comparable to the [Ca2+]i change due to a Ca2+ spike. IP3-mediated Ca2+ release also was observed in the presence of the metabotropic agonists t-ACPD and carbachol when backpropagating spikes were generated. Ca2+ entry through NMDA receptors was observed primarily on the oblique dendrites. The main differences between waves in neocortical neurons and in previously described hippocampal pyramidal neurons were, (a) Ca2+ waves in L5 neurons could be evoked further out along the main shaft, (b) Ca2+ waves extended slightly further out into the oblique dendrites and (c) higher concentrations of bath-applied t-ACPD and carbachol were required to generate Ca2+ release events by backpropagating action potentials. PMID:12692172

Discontinuity of the annuity curves. III. Two types of vital variability in Drosophila melanogaster.

PubMed

Bychkovskaia, I B; Mylnikov, S V; Mozhaev, G A

2016-01-01

We confirm five-phased construction of Drosophila annuity curves established earlier. Annuity curves were composed of stable five-phase component and variable one. Variable component was due to differences in phase durations. As stable, so variable components were apparent for 60 generations. Stochastic component was described as well. Viability variance which characterize «reaction norm» was apparent for all generation as well. Thus, both types of variability seem to be inherited.

Analysis of International Space Station Vehicle Materials Exposed on Materials International Space Station Experiment from 2001 to 2011

NASA Technical Reports Server (NTRS)

Finckenor, M. M.; Golden, J. L.; Kravchenko, M.

2013-01-01

Since August 2001, the Materials on International Space Station Experiment (MISSE) has provided data on a variety of materials and spacecraft components, including samples chosen to provide sustaining engineering and life extension data for the International Space Station vehicle itself. This Technical Publication is by no means a complete set of MISSE data but does provide changes in solar absorptance, infrared emittance, and visual appearance due to atomic oxygen, ultraviolet radiation, and thermal cycling in vacuum. Conversion coatings, anodizes, thermal control coatings with organic and inorganic binders, multilayer insulation components, optical materials, and part markings are discussed.

Portable spark-gap arc generator

NASA Technical Reports Server (NTRS)

Ignaczak, L. R.

1978-01-01

Self-contained spark generator that simulates electrical noise caused by discharge of static charge is useful tool when checking sensitive component and equipment. In test set-up, device introduces repeatable noise pulses as behavior of components is monitored. Generator uses only standard commercial parts and weighs only 4 pounds; portable dc power supply is used. Two configurations of generator have been developed: one is free-running arc source, and one delivers spark in response to triggering pulse.

Cellular generators of the cortical auditory evoked potential initial component.

PubMed

Steinschneider, M; Tenke, C E; Schroeder, C E; Javitt, D C; Simpson, G V; Arezzo, J C; Vaughan, H G

1992-01-01

Cellular generators of the initial cortical auditory evoked potential (AEP) component were determined by analyzing laminar profiles of click-evoked AEPs, current source density, and multiple unit activity (MUA) in primary auditory cortex of awake monkeys. The initial AEP component is a surface-negative wave, N8, that peaks at 8-9 msec and inverts in polarity below lamina 4. N8 is generated by a lamina 4 current sink and a deeper current source. Simultaneous MUA is present from lower lamina 3 to the subjacent white matter. Findings indicate that thalamocortical afferents are a generator of N8 and support a role for lamina 4 stellate cells. Relationships to the human AEP are discussed.

The new Kuznets cycle: a test of the Easterlin-Wachter-Wachter hypothesis.

PubMed

Ahlburg, D A

1982-01-01

The aim of this paper is to evaluate the Easterlin-Wachter-Wachter model of the effect of the size of one generation on the size of the succeeding generation. An attempt is made "to identify and test empirically each component of the Easterlin-Wachter-Wachter model..., to show how the components collapse to give a closed demographic model of generation size, and to investigate the impacts of relative cohort size on the economic performance of a cohort." The models derived are then used to generate forecasts of the U.S. birth rate to the year 2050. The results provide support for the major components of the original model. excerpt

Analysis of temperature and pressure distribution of containers for nuclear waste material disposal in space

NASA Technical Reports Server (NTRS)

Vanbibber, L. E.; Parker, W. G.

1973-01-01

A computer program was adapted from a previous generation program to analyze the temperature and internal pressure response of a radioactive nuclear waste material disposal container following impact on the earth. This program considers component melting, LiH dissociation, temperature dependent properties and pressure and container stress response. Analyses were performed for 21 cases with variations in radioactive power level, container geometry, degree of deformation of the container, degree of burial and soil properties. Results indicated that the integrity of SS-316 containers could be maintained with partial burials of either underformed or deformed containers. Results indicated that completely buried waste containers, with power levels above 5 kW, experienced creep stress rupture failures in 4 to 12 days.

Pressure Measurement Sensor

NASA Technical Reports Server (NTRS)

1997-01-01

FFPI Industries Inc. is the manufacturer of fiber-optic sensors that furnish accurate pressure measurements in internal combustion chambers. Such an assessment can help reduce pollution emitted by these engines. A chief component in the sensor owes its seven year- long development to Lewis Research Center funding to embed optical fibers and sensors in metal parts. NASA support to Texas A&M University played a critical role in developing this fiber optic technology and led to the formation of FFPI Industries and the production of fiber sensor products. The simple, rugged design of the sensor offers the potential for mass production at low cost. Widespread application of the new technology is forseen, from natural gas transmission, oil refining and electrical power generation to rail transport and the petrochemical paper product industry.

Description and initial operating performance of the Langley 6-inch expansion tube using heated helium driver gas

NASA Technical Reports Server (NTRS)

Moore, J. A.

1975-01-01

A general description of the Langley 6-inch expansion tube is presented along with discussion of the basic components, internal resistance heater, arc-discharge assemblies, instrumentation, and operating procedure. Preliminary results using unheated and resistance-heated helium as the driver gas are presented. The driver-gas pressure ranged from approximately 17 to 59 MPa and its temperature ranged from 300 to 510 K. Interface velocities of approximately 3.8 to 6.7 km/sec were generated between the test gas and the acceleration gas using air as the test gas and helium as the acceleration gas. Test flow quality and comparison of measured and predicted expansion-tube flow quantities are discussed.

Damage Arresting Composites for Shaped Vehicles

NASA Technical Reports Server (NTRS)

Velicki, Alex

2009-01-01

This report describes the development of a novel structural solution that addresses the demanding fuselage loading requirements for the Hybrid Wing or Blended Wing Body configurations that are described in NASA NRA subtopic A2A.3, "Materials and Structures for Wing Components and Non-Circular Fuselage." The phase I portion of this task includes a comprehensive finite element model-based structural sizing exercise performed using the BWB airplane configuration to generate internal loads and fuselage panel weights for an advanced Pultruded Rod Stitched Efficient Unitized Structure (PRSEUS) structural concept. An accompanying element-level test program is also described which substantiates the analytical results and calculation methods used in the trade study. The phase II plan for the continuation of this research is also included herein.

Regenerative Environmental Control and Life Support System Diagram

NASA Technical Reports Server (NTRS)

2000-01-01

This diagram shows the flow of recyclable resources in the International Space Station (ISS). The Environmental Control and Life Support System (ECLSS) Group of the Flight Projects Directorate at the Marshall Space Flight Center is responsible for the regenerative ECLSS hardware, as well as providing technical support for the rest of the system. The regenerative ECLSS, whose main components are the Water Recovery System (WRS), and the Oxygen Generation System (OGS), reclaims and recycles water and oxygen. The ECLSS maintains a pressurized habitation environment, provides water recovery and storage, maintains and provides fire detection / suppression, and provides breathable air and a comfortable atmosphere in which to live and work within the ISS. The ECLSS hardware will be located in the Node 3 module of the ISS.

Printable, flexible and stretchable diamond for thermal management

DOEpatents

Rogers, John A; Kim, Tae Ho; Choi, Won Mook; Kim, Dae Hyeong; Meitl, Matthew; Menard, Etienne; Carlisle, John

2013-06-25

Various heat-sinked components and methods of making heat-sinked components are disclosed where diamond in thermal contact with one or more heat-generating components are capable of dissipating heat, thereby providing thermally-regulated components. Thermally conductive diamond is provided in patterns capable of providing efficient and maximum heat transfer away from components that may be susceptible to damage by elevated temperatures. The devices and methods are used to cool flexible electronics, integrated circuits and other complex electronics that tend to generate significant heat. Also provided are methods of making printable diamond patterns that can be used in a range of devices and device components.

Proposal of ultrasonic-assisted mid-infrared spectroscopy for incorporating into daily life like smart-toilet and non-invasive blood glucose sensor

NASA Astrophysics Data System (ADS)

Kitazaki, Tomoya; Mori, Keita; Yamamoto, Naoyuki; Wang, Congtao; Kawashima, Natsumi; Ishimaru, Ichiro

2017-07-01

We proposed the extremely compact beans-size snap-shot mid-infrared spectroscopy that will be able to be built in smartphones. And also the easy preparation method of thin-film samples generated by ultrasonic standing wave is proposed. Mid-infrared spectroscopy is able to identify material components and estimate component concentrations quantitatively from absorption spectra. But conventional spectral instruments were very large-size and too expensive to incorporate into daily life. And preparations of thin-film sample were very troublesome task. Because water absorption in mid-infrared lights is very strong, moisture-containing-sample thickness should be less than 100[μm]. Thus, midinfrared spectroscopy has been utilized only by analytical experts in their laboratories. Because ultrasonic standing wave is compressional wave, we can generate periodical refractive-index distributions inside of samples. A high refractiveindex plane is correspond to a reflection boundary. When we use a several MHz ultrasonic transducer, the distance between sample surface and generated first node become to be several ten μm. Thus, the double path of this distance is correspond to sample thickness. By combining these two proposed methods, as for liquid samples, urinary albumin and glucose concentrations will be able to be measured inside of toilet. And as for solid samples, by attaching these apparatus to earlobes, the enhancement of reflection lights from near skin surface will create a new path to realize the non-invasive blood glucose sensor. Using the small ultrasonic-transducer whose diameter was 10[mm] and applied voltage 8[V], we detected the internal reflection lights from colored water as liquid sample and acrylic board as solid sample.

Effects of myelin or cell body brainstem lesions on 3-channel Lissajous' trajectories of feline auditory brainstem evoked potentials.

PubMed

Pratt, H; Zaaroor, M; Bleich, N; Starr, A

1991-06-01

Auditory brainstem evoked potentials (ABEP) were recorded from 16 awake cats to obtain 3-Channel Lissajous' Trajectories (3CLTs) using three orthogonal differential electrode configurations (nasion-midline nuchal ridge, left-right mastoids, vertex-midline under the mandible). Potentials, evoked by monaural 80 dBnHL (re, human threshold) clicks, were studied before, and up to 7 weeks after inducing neuronal lesions localized to the cochlear nucleus (CN) or the superior olivary complex (SOC), or myelin lesions localized to the fibers of the trapezoid body connecting these two structures. Neuronal lesions were induced by injection of kainic acid (KA), while myelin lesions were induced by injection of L-alpha-lysophosphatidylcholine (LPC). With CN neuronal lesions the major changes in 3CLT were in the time domain of 'b', 'c' and 'd' (components P2, P3 and P4 of single-channel ABEP). With SOC neuronal lesions the major changes were in 'c' and 'd' of 3CLT (P3 and P4 of ABEP). With trapezoid body lesions the major change was in 'c' (P3 of ABEP). The results are compatible with the peripheral generation of the first ABEP components (P1a and P1b). The second component (P2) is generated by ipsilateral CN neurones and their outputs. The third component (P3) is generated primarily by ipsilateral SOC neurones and their outputs, with the ipsilateral CN providing input. The The fourth component (P4) is generated bilaterally by the SOC neurones and their outputs, receiving their inputs from ipsilateral CN. The fifth ABEP component (P5) is generated by structures central to the SOCs and their immediate outputs. Neither focal neuronal nor myelin lesions were sufficient to produce obliteration of any component, consistent with a set of generators for each of the ABEP components, consisting of both cell bodies and their output fibers, that is distributed spatially in the brainstem.

The role of appearance schematicity in the internalization of media appearance ideals: A panel study of preadolescents.

PubMed

Rousseau, Ann; Gamble, Hilary; Eggermont, Steven

2017-10-01

Individuals who are more strongly invested in their appearance, appearance schematics, have a tendency to engage in appearance-related comparison. Appearance schematicity consists of two components. The self-evaluative component concerns the degree to which appearance is central to self-worth, referred to as dysfunctional appearance beliefs. Motivational salience refers to the engagement in behaviors designed to enhance appearance, such as body surveillance. Based on a three-wave panel survey of 973 Flemish preadolescents (M age  = 11.15, SD = 1.13) we found that the motivational and self-evaluative components had a different impact on media internalization. For preadolescents who engaged in more body surveillance, watching television resulted in more media internalization. For preadolescents who had fewer dysfunctional appearance beliefs, watching television resulted in more media internalization. These findings suggest that appearance schematicity is an important susceptibility variable in the relationship between TV-exposure and media internalization, and emphasize the importance of investigating individual dispositions beyond gender differences. Copyright © 2017 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

Tetris is a foldback transposon that provided the building blocks for an emerging satellite DNA of Drosophila virilis.

PubMed

Dias, Guilherme B; Svartman, Marta; Delprat, Alejandra; Ruiz, Alfredo; Kuhn, Gustavo C S

2014-05-24

Transposable elements (TEs) and satellite DNAs (satDNAs) are abundant components of most eukaryotic genomes studied so far and their impact on evolution has been the focus of several studies. A number of studies linked TEs with satDNAs, but the nature of their evolutionary relationships remains unclear. During in silico analyses of the Drosophila virilis assembled genome, we found a novel DNA transposon we named Tetris based on its modular structure and diversity of rearranged forms. We aimed to characterize Tetris and investigate its role in generating satDNAs. Data mining and sequence analysis showed that Tetris is apparently nonautonomous, with a structure similar to foldback elements, and present in D. virilis and D. americana. Herein, we show that Tetris shares the final portions of its terminal inverted repeats (TIRs) with DAIBAM, a previously described miniature inverted transposable element implicated in the generation of chromosome inversions. Both elements are likely to be mobilized by the same autonomous TE. Tetris TIRs contain approximately 220-bp internal tandem repeats that we have named TIR-220. We also found TIR-220 repeats making up longer (kb-size) satDNA-like arrays. Using bioinformatic, phylogenetic and cytogenomic tools, we demonstrated that Tetris has contributed to shaping the genomes of D. virilis and D. americana, providing internal tandem repeats that served as building blocks for the amplification of satDNA arrays. The β-heterochromatic genomic environment seemed to have favored such amplification. Our results imply for the first time a role for foldback elements in generating satDNAs. © The Author(s) 2014. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

Calcium responses to synaptically activated bursts of action potentials and their synapse-independent replay in cultured networks of hippocampal neurons.

PubMed

Bengtson, C Peter; Kaiser, Martin; Obermayer, Joshua; Bading, Hilmar

2013-07-01

Both synaptic N-methyl-d-aspartate (NMDA) receptors and voltage-operated calcium channels (VOCCs) have been shown to be critical for nuclear calcium signals associated with transcriptional responses to bursts of synaptic input. However the direct contribution to nuclear calcium signals from calcium influx through NMDA receptors and VOCCs has been obscured by their concurrent roles in action potential generation and synaptic transmission. Here we compare calcium responses to synaptically induced bursts of action potentials with identical bursts devoid of any synaptic contribution generated using the pre-recorded burst as the voltage clamp command input to replay the burst in the presence of blockers of action potentials or ionotropic glutamate receptors. Synapse independent replays of bursts produced nuclear calcium responses with amplitudes around 70% of their original synaptically generated signals and were abolished by the L-type VOCC blocker, verapamil. These results identify a major direct source of nuclear calcium from local L-type VOCCs whose activation is boosted by NMDA receptor dependent depolarization. The residual component of synaptically induced nuclear calcium signals which was both VOCC independent and NMDA receptor dependent showed delayed kinetics consistent with a more distal source such as synaptic NMDA receptors or internal stores. The dual requirement of NMDA receptors and L-type VOCCs for synaptic activity-induced nuclear calcium dependent transcriptional responses most likely reflects a direct somatic calcium influx from VOCCs whose activation is amplified by synaptic NMDA receptor-mediated depolarization and whose calcium signal is boosted by a delayed input from distal calcium sources mostly likely entry through NMDA receptors and release from internal stores. This article is part of a Special Issue entitled: 12th European Symposium on Calcium. Copyright © 2013 Elsevier B.V. All rights reserved.

Vibration energy harvesting based on integrated piezoelectric components operating in different modes.

PubMed

Hu, Junhui; Jong, Januar; Zhao, Chunsheng

2010-01-01

To increase the vibration energy-harvesting capability of the piezoelectric generator based on a cantilever beam, we have proposed a piezoelectric generator that not only uses the strain change of piezoelectric components bonded on a cantilever beam, but also employs the weights at the tip of the cantilever beam to hit piezoelectric components located on the 2 sides of weights. A prototype of the piezoelectric generator has been fabricated and its characteristics have been measured and analyzed. The experimental results show that the piezoelectric components operating in the hit mode can substantially enhance the energy harvesting of the piezoelectric generator on a cantilever beam. Two methods are used and compared in the management of rectified output voltages from different groups of piezoelectric components. In one of them, the DC voltages from rectifiers are connected in series, and then the total DC voltage is applied to a capacitor. In another connection, the DC voltage from each group is applied to different capacitors. It is found that 22.3% of the harvested energy is wasted due to the series connection. The total output electric energy of our piezoelectric generator at nonresonance could be up to 43 nJ for one vibration excitation applied by spring, with initial vibration amplitude (0-p) of 18 mm and frequency of 18.5 Hz, when the rectified voltages from different groups of piezoelectric components are connected to their individual capacitors. In addition, the motion and impact of the weights at the tip of the cantilever beam are theoretically analyzed, which well explains the experimental phenomena and suggests the measures to improve the generator.

Magnitude And Distance Determination From The First Few Seconds Of One Three Components Seismological Station Signal Using Support Vector Machine Regression Methods

NASA Astrophysics Data System (ADS)

Ochoa Gutierrez, L. H.; Vargas Jimenez, C. A.; Niño Vasquez, L. F.

2011-12-01

The "Sabana de Bogota" (Bogota Savannah) is the most important social and economical center of Colombia. Almost the third of population is concentrated in this region and generates about the 40% of Colombia's Internal Brute Product (IBP). According to this, the zone presents an elevated vulnerability in case that a high destructive seismic event occurs. Historical evidences show that high magnitude events took place in the past with a huge damage caused to the city and indicate that is probable that such events can occur in the next years. This is the reason why we are working in an early warning generation system, using the first few seconds of a seismic signal registered by three components and wide band seismometers. Such system can be implemented using Computational Intelligence tools, designed and calibrated to the particular Geological, Structural and environmental conditions present in the region. The methods developed are expected to work on real time, thus suitable software and electronic tools need to be developed. We used Support Vector Machines Regression (SVMR) methods trained and tested with historic seismic events registered by "EL ROSAL" Station, located near Bogotá, calculating descriptors or attributes as the input of the model, from the first 6 seconds of signal. With this algorithm, we obtained less than 10% of mean absolute error and correlation coefficients greater than 85% in hypocentral distance and Magnitude estimation. With this results we consider that we can improve the method trying to have better accuracy with less signal time and that this can be a very useful model to be implemented directly in the seismological stations to generate a fast characterization of the event, broadcasting not only raw signal but pre-processed information that can be very useful for accurate Early Warning Generation.

Spatio-temporal variability of internal waves in the northern Gulf of Mexico studied with the Navy Coastal Ocean Model, NCOM

NASA Astrophysics Data System (ADS)

Cambazoglu, M. K.; Jacobs, G. A.; Howden, S. D.; Book, J. W.; Arnone, R.; Soto Ramos, I. M.; Vandermeulen, R. A.; Greer, A. T.; Miles, T. N.

2016-02-01

Internal waves enhance mixing in the upper ocean, transport nutrients and plankton over the water column and across the shelf from deeper waters to shallower coastal areas, and could also transport pollutants such as hydrocarbons onshore during an oil spill event. This study aims to characterize internal waves in the northern Gulf of Mexico (nGoM) and investigate the possible generation and dissipation mechanisms using a high-resolution (1-km) application of the Navy Coastal Ocean Model (NCOM). Three dimensional model products are used to detect the propagation patterns of internal waves. The vertical structure of internal waves is studied and the role of stratification is analyzed by looking at the temperature, salinity and velocity variations along the water column. The model predictions suggest the generation of internal waves on the continental shelf, therefore the role of ocean bottom topography interacting with tides and general circulation features such as the Loop Current Eddy front, on the internal wave generation will be discussed. The time periods of internal wave occurrences are identified from model predictions and compared to satellite ocean color imagery. Further data analysis, e.g. Fourier analysis, is implemented to determine internal wavelengths and frequencies and to determine if the response of internal waves are at tidal periods or at different frequencies. The atmospheric forcing provided to NCOM and meteorological data records are analyzed to define the interaction between wind forcing and internal wave generation. Wavelet analysis characterizes the ocean response to atmospheric events with periodic frequencies. Ocean color satellite imagery was used to visualize the location of the Mississippi river plume (and other oceanic features) and compared to the model predictions because the enhanced stratification from freshwater plumes which propagate across the Mississippi Bight can provide favorable conditions in coastal waters for internal wave generation and propagation. The findings of this study will provide insight about the internal wave dynamics in the Gulf of Mexico and their potential impact on the marine ecosystem.

Internal split field generator

DOEpatents

Thundat,; George, Thomas [Knoxville, TN; Van Neste, Charles W [Kingston, TN; Vass, Arpad Alexander [Oak Ridge, TN

2012-01-03

A generator includes a coil of conductive material. A stationary magnetic field source applies a stationary magnetic field to the coil. An internal magnetic field source is disposed within a cavity of the coil to apply a moving magnetic field to the coil. The stationary magnetic field interacts with the moving magnetic field to generate an electrical energy in the coil.

Long-term effects of internment during early childhood on third-generation Japanese Americans.

PubMed

Nagata, D K; Trierweiler, S J; Talbot, R

1999-01-01

A national survey investigated the long-term effects of World War II internment on family communication, ethnic preference, confidence in personal rights, and attitudes to redress among third-generation Japanese Americans (sansei) who were infants or young children during incarceration. Findings were compared to those for noninterned sansei with and without parents who had been interned. Differences between interned and noninterned sansei were found primarily in family communication and family distance.

Real-Time External Respiratory Motion Measuring Technique Using an RGB-D Camera and Principal Component Analysis †

PubMed Central

Wijenayake, Udaya; Park, Soon-Yong

2017-01-01

Accurate tracking and modeling of internal and external respiratory motion in the thoracic and abdominal regions of a human body is a highly discussed topic in external beam radiotherapy treatment. Errors in target/normal tissue delineation and dose calculation and the increment of the healthy tissues being exposed to high radiation doses are some of the unsolicited problems caused due to inaccurate tracking of the respiratory motion. Many related works have been introduced for respiratory motion modeling, but a majority of them highly depend on radiography/fluoroscopy imaging, wearable markers or surgical node implanting techniques. We, in this article, propose a new respiratory motion tracking approach by exploiting the advantages of an RGB-D camera. First, we create a patient-specific respiratory motion model using principal component analysis (PCA) removing the spatial and temporal noise of the input depth data. Then, this model is utilized for real-time external respiratory motion measurement with high accuracy. Additionally, we introduce a marker-based depth frame registration technique to limit the measuring area into an anatomically consistent region that helps to handle the patient movements during the treatment. We achieved a 0.97 correlation comparing to a spirometer and 0.53 mm average error considering a laser line scanning result as the ground truth. As future work, we will use this accurate measurement of external respiratory motion to generate a correlated motion model that describes the movements of internal tumors. PMID:28792468

Cosmic rays flux and geomagnetic field variations at midlatitudes

NASA Astrophysics Data System (ADS)

Morozova, Anna; Ribeiro, Paulo; Tragaldabas Collaboration Team

2014-05-01

It is well known that the cosmic rays flux is modulated by the solar wind and the Earth's magnetic field. The Earth's magnetic field deflects charged particles in accordance with their momentum and the local field strength and direction. The geomagnetic cutoffs depend both on the internal and the external components of the geomagnetic field, therefore reflecting the geodynamo and the solar activity variations. A new generation, high performance, cosmic ray detector Tragaldabas was recently installed at the University of Santiago de Compostela (Spain). The detector has been acquiring test data since September 2013 with a rate of about 80 events/s over a solid angle of ~5 srad. around the vertical direction. To take full advantage of this new facility for the study of cosmic rays arriving to the Earth, an international collaboration has been organized, of about 20 researchers from 10 laboratories of 5 European countries. The Magnetic Observatory of Coimbra (Portugal) has been measuring the geomagnetic field components for almost 150 years since the first measurements in 1866. It is presently equipped with up-to-date instruments. Here we present a preliminary analysis of the global cosmic ray fluxes acquired by the new Tragaldabas detector in relation to the geomagnetic field variations measured by the Coimbra observatory. We also compare the data from the new cosmic rays detector with results obtained by the Castilla-La Mancha Neutron Monitor (CaLMa, Gadalajara, Spain) that is in operation since October 2011.

Evaluation of the Low Heat Input Process for Weld Repair of Nickel-Base Superalloys

NASA Astrophysics Data System (ADS)

Durocher, J.; Richards, N. L.

2011-10-01

The repair of turbine blades and vanes commonly involves gas tungsten arc welding or an equivalent process, but unfortunately these components are often susceptible to heat-affected zone (HAZ) cracking during the weld repair process. This is a major problem especially in cast alloys due to their coarse-grain size and where the (Al + Ti) contents is in excess of 3-4%; vacuum brazing is also used but mainly on low stress non-rotating components such as vanes. Micro-welding has the potential to deposit small amounts of filler at low heat input levels with minimum HAZ and thus is an attractive process for depositing a quality weld. As with conventional fusion processes, the filler alloy is deposited by the generation of a low power arc between a consumable electrode and the substrate. The low heat input of this process offers unique advantages over more common welding processes such as gas tungsten arc, plasma arc, laser, and electron beam welding. In this study, the low heat input characteristic of micro-welding has been used to simulate weld repair using Inconel (IN) (Inconel and IN are trademarks of INCO Alloys International) 625, Rene (Rene is a trademark of General Electric Company) 41, Nimonic (Nimonic is a trademark of INCO Alloys International) 105 and Inconel 738LC filler alloys, to a cast Inconel 738LC substrate. The effect of micro-welding process parameters on the deposition rate, coating quality, and substrate has been investigated.

Airborne synthetic aperture radar tracking of internal waves in the Strait of Gibraltar

NASA Astrophysics Data System (ADS)

Richez, Claude

As part of the International “Gibraltar Experiment”, we realized, on June 22 and 24, 1986, two surveys of the Strait of Gibraltar, on board an aircraft equipped with a Synthetic Aperture Radar. Our objective was to observe, at Spring tides, and during two twelve-hour tidal cycles, at 24 h interval, the generation of internal wave trains, linked to the hydraulic jump formed west of the sill during the westward phase of the tidal current, and their eastward propagation in the Strait. The speed of propagation of these waves and the effect of the diurnal component of the tide on their generation and propagation could then be determined. Our results suggest that two solitary waves of equal amplitude propagated eastwards in the strait on June 22 (the tidal coefficient being equal to 92), with a speed, relative to the ground, of 2.1 to 2.6 m s -1. 24 h later, during the second survey, on June 24 (tidal coefficient 90), we observed the propagation of a train of non-linear waves, the speed of the leading wave of which being about 1.9 ms -1. Our data show that other waves pass over the Camarinal Sill after the release of the bore, and “secondary” internal wave trains are shown to propagate eastwards from there. Although our SAR data show the appearance of waves west of the northern sill at about 4 h after High Water (HW), the mechanism leading to their generation is not clear. These waves could propagate eastwards, all along the strait, and/or northwestwards along the western Spanish coast. They could be responsible for the solitary-type events observed at the eastern entrance of the strait, at about 7 h after HW, by ZIEGENBEIN (1969, 1970). These events are noticeable in the hydrological parameters time series of ARMI and FARMER (1988) and in the high rate current data (2-min apart) from their April 1986 cruise. Besides these alongstrait waves, our SAR data show the existence of cross-strait waves, and give an idea of their wavelength and speed of propagation. Their presence leads to perturbations in the current, revealed by simultaneous current data, at the Camarinal Sill and north of Cape Cires.

Graphical Language for Data Processing

NASA Technical Reports Server (NTRS)

Alphonso, Keith

2011-01-01

A graphical language for processing data allows processing elements to be connected with virtual wires that represent data flows between processing modules. The processing of complex data, such as lidar data, requires many different algorithms to be applied. The purpose of this innovation is to automate the processing of complex data, such as LIDAR, without the need for complex scripting and programming languages. The system consists of a set of user-interface components that allow the user to drag and drop various algorithmic and processing components onto a process graph. By working graphically, the user can completely visualize the process flow and create complex diagrams. This innovation supports the nesting of graphs, such that a graph can be included in another graph as a single step for processing. In addition to the user interface components, the system includes a set of .NET classes that represent the graph internally. These classes provide the internal system representation of the graphical user interface. The system includes a graph execution component that reads the internal representation of the graph (as described above) and executes that graph. The execution of the graph follows the interpreted model of execution in that each node is traversed and executed from the original internal representation. In addition, there are components that allow external code elements, such as algorithms, to be easily integrated into the system, thus making the system infinitely expandable.

Method and Apparatus for Non-Invasive Measurement of Changes in Intracranial Pressure

NASA Technical Reports Server (NTRS)

Yost, William T. (Inventor); Cantrell, John H., Jr. (Inventor)

2004-01-01

A method and apparatus for measuring intracranial pressure. In one embodiment, the method comprises the steps of generating an information signal that comprises components (e.g., pulsatile changes and slow changes) that are related to intracranial pressure and blood pressure, generating a reference signal comprising pulsatile components that are solely related to blood pressure, processing the information and reference signals to determine the pulsatile components of the information signal that have generally the same phase as the pulsatile components of the reference signal, and removing from the information signal the pulsatile components determined to have generally the same phase as the pulsatile components of the reference signal so as to provide a data signal having components wherein substantially all of the components are related to intracranial pressure.

Nonlinear Internal Tide Generation at the Luzon Strait: Integrating Laboratory Data with Numerics and Observations

DTIC Science & Technology

2008-09-30

Nonlinear Internal Tide Generation at the Luzon Strait: Integrating Laboratory Data with Numerics and...laboratory experimental techniques have greatly enhanced the ability to obtained detailed spatiotemporal data for internal waves in challenging regimes...a custom configured wave tank; and to integrate these results with data obtained from numerical simulations, theory and field studies. The principal

Characteristics of the internal and external sources of the Mediterranean synoptic cyclones for the period 1956-2013

NASA Astrophysics Data System (ADS)

Almazroui, Mansour; Awad, Adel M.; Nazrul Islam, M.

2017-07-01

This paper investigates the main sources and features of the Mediterranean synoptic cyclones affecting the basin, using the cyclone tracks. The cyclones' tracks are identified using sea level pressure (SLP) from the NCEP/NCAR reanalysis data for the period 1956-2013. The identified cyclones are classified into two categories: basin affected and basin non-affected. Most of the basin-affected (non-affected) cyclones are internal (external), i.e., generated inside (outside) the Mediterranean basin. This study reveals four (five) main sources of internal (external) cyclones. These four (five) main sources generated about 63.76% (57.25%) of the internal (external) cyclones. Seasonal analysis shows that most of the basin-affected internal (external) cyclones were generated in the winter (spring) season. The lowest number of cyclones were found in the summer. Moreover, the synoptic study of the atmospheric systems accompanied the highest- and lowest-generated years demonstrates that the deepening of the north Europe cyclones and the relative positions of Azores- and Siberian-high systems represent the important factors that influence the number of internal cyclones. Essential factors influencing the external cyclones are the strength of the maximum upper wind, Azores high, Siberian high, and orientations of their ridges.

[Promising Future in General Internal Medicine for the Next Generation of Physicians].

PubMed

Allenbach, Victoria Perpinias; Rozsnyai, Zsofia; Streit, Sven

2018-06-01

Promising Future in General Internal Medicine for the Next Generation of Physicians Abstract. We are facing a lack of specialists in general internal medicine in general practitioners' practices as well as in hospitals, while at the same time the population ages and usually displays several chronic diseases (multimorbidity). Thanks to more university places, an improved job description for general internal medicine and new further education offers (curricula), interest in general internal medicine increased again, as surveys of students indicate. The young generation of family doctors and generalists in hospitals wishes flexible working conditions in order to reconcile work, family and spare time in the best possible way. Working atmosphere and colleagues have a high priority. These wishes must now be incorporated into attractive further training with flexible curricula and mentoring offers so that young talents can successfully be promoted.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Meehl, G A; Covey, C; McAvaney, B

The Coupled Model Intercomparison Project (CMIP) is designed to allow study and intercomparison of multi-model simulations of present-day and future climate. The latter are represented by idealized forcing of compounded 1% per year CO2 increase to the time of CO2 doubling near year 70 in simulations with global coupled models that contain, typically, components representing atmosphere, ocean, sea ice and land surface. Results from CMIP diagnostic subprojects were presented at the Second CMIP Workshop held at the Max Planck Institute for Meteorology in Hamburg, Germany, in September, 2003. Significant progress in diagnosing and understanding results from global coupled models hasmore » been made since the First CMIP Workshop in Melbourne, Australia in 1998. For example, the issue of flux adjustment is slowly fading as more and more models obtain stable multi-century surface climates without them. El Nino variability, usually about half the observed amplitude in the previous generation of coupled models, is now more accurately simulated in the present generation of global coupled models, though there are still biases in simulating the patterns of maximum variability. Typical resolutions of atmospheric component models contained in coupled models is now usually around 2.5 degrees latitude-longitude, with the ocean components often having about twice the atmospheric model resolution, with even higher resolution in the equatorial tropics. Some new-generation coupled models have atmospheric model resolutions of around 1.5 degrees latitude-longitude. Modeling groups now routinely run the CMIP control and 1% CO2 simulations in addition to 20th and 21st century climate simulations with a variety of forcings (e.g. volcanoes, solar variability, anthropogenic sulfate aerosols, ozone, and greenhouse gases (GHGs), with the anthropogenic forcings for future climate as well). However, persistent systematic errors noted in previous generations of global coupled models still are present in the present generation (e.g. over-extensive equatorial Pacific cold tongue, double ITCZ). This points to the next challenge for the global coupled climate modeling community. Planning and imminent commencement of the IPCC Fourth Assessment Report (AR4) has prompted rapid coupled model development, which will lead to an expanded CMIP-like activity to collect and analyze results for the control, 1% CO2, 20th, 21st and 22nd century simulations performed for the AR4. The international climate community is encouraged to become involved in this analysis effort, and details are provided below in how to do so.« less

Dynamic refractometer

NASA Technical Reports Server (NTRS)

Curley, Michael J. (Inventor); Sarkisov, Sergey S. (Inventor)

2008-01-01

A refractometer computer controls the rotation of a rotary plate upon which are mounted a prism optically coupled via an optical window to a spectroscopic cell holding a resin exhibiting a dynamic refractive index during photocuring. The computer system positions the prism and spectroscopic cell relative to a visible light laser which illuminates the prism-resin interface at selected incidence angles. A photodetector mounted on the plate generates a signal to the computer proportional to intensity of an internally reflected light beam. A curing light is selectively transmitted through the prism and into the photocurable resin. The refractometer determines the intensity of the internally reflected beam a selected incidence angles and determines the effective refractive index curve of the resin at an uncured state and, optionally, at a completely cured state. Next, an amount of uncured resin and selected optical components to be joined by the resin is placed in the spectroscopic cell and irradiated with the UV light. The refractometer is fixed at a selected incidence angle and measures the intensity of an internally reflected light beam of light throughout the cure cycle. The refractometer determines the resin's refractive index of the polymeric mixture by means of extrapolation of a horizontal shift in the effective refractive index curve of the resin from an uncured state to a selected point in the cure cycle.

Three-dimensional measurement of small inner surface profiles using feature-based 3-D panoramic registration

PubMed Central

Gong, Yuanzheng; Seibel, Eric J.

2017-01-01

Rapid development in the performance of sophisticated optical components, digital image sensors, and computer abilities along with decreasing costs has enabled three-dimensional (3-D) optical measurement to replace more traditional methods in manufacturing and quality control. The advantages of 3-D optical measurement, such as noncontact, high accuracy, rapid operation, and the ability for automation, are extremely valuable for inline manufacturing. However, most of the current optical approaches are eligible for exterior instead of internal surfaces of machined parts. A 3-D optical measurement approach is proposed based on machine vision for the 3-D profile measurement of tiny complex internal surfaces, such as internally threaded holes. To capture the full topographic extent (peak to valley) of threads, a side-view commercial rigid scope is used to collect images at known camera positions and orientations. A 3-D point cloud is generated with multiview stereo vision using linear motion of the test piece, which is repeated by a rotation to form additional point clouds. Registration of these point clouds into a complete reconstruction uses a proposed automated feature-based 3-D registration algorithm. The resulting 3-D reconstruction is compared with x-ray computed tomography to validate the feasibility of our proposed method for future robotically driven industrial 3-D inspection. PMID:28286351

Three-dimensional measurement of small inner surface profiles using feature-based 3-D panoramic registration

NASA Astrophysics Data System (ADS)

Gong, Yuanzheng; Seibel, Eric J.

2017-01-01

Rapid development in the performance of sophisticated optical components, digital image sensors, and computer abilities along with decreasing costs has enabled three-dimensional (3-D) optical measurement to replace more traditional methods in manufacturing and quality control. The advantages of 3-D optical measurement, such as noncontact, high accuracy, rapid operation, and the ability for automation, are extremely valuable for inline manufacturing. However, most of the current optical approaches are eligible for exterior instead of internal surfaces of machined parts. A 3-D optical measurement approach is proposed based on machine vision for the 3-D profile measurement of tiny complex internal surfaces, such as internally threaded holes. To capture the full topographic extent (peak to valley) of threads, a side-view commercial rigid scope is used to collect images at known camera positions and orientations. A 3-D point cloud is generated with multiview stereo vision using linear motion of the test piece, which is repeated by a rotation to form additional point clouds. Registration of these point clouds into a complete reconstruction uses a proposed automated feature-based 3-D registration algorithm. The resulting 3-D reconstruction is compared with x-ray computed tomography to validate the feasibility of our proposed method for future robotically driven industrial 3-D inspection.

Toward Realistic Dynamics of Rotating Orbital Debris, and Implications for Lightcurve Interpretation

NASA Technical Reports Server (NTRS)

Ojakangas, Gregory W.; Cowardin, H.; Hill, N.

2011-01-01

Optical observations of rotating space debris near GEO contain important information on size, shape, composition, and rotational states, but these aspects are difficult to extract due to data limitations and the high number of degrees of freedom in the modeling process. For tri-axial rigid debris objects created by satellite fragmentations, the most likely initial rotation state has a large component of initial angular velocity directed along the intermediate axis of inertia, leading to large angular reorientations of the body on the timescale of the rotation period. This lends some support to the simplest possible interpretation of light curves -- that they represent sets of random orientations of the objects of study. However, effects of internal friction and solar radiation are likely to cause significant modification of rotation states within a time as short as a few orbital periods. In order to examine the rotational dynamics of debris objects under the influences of these effects, a set of seven first-order coupled equations of motion were assembled in state form: three are Euler equations describing the rates of change of the components of angular velocity in the body frame, and four describe the rates of change of the components of the unit quaternion. Quaternions are a four-dimensional extension of complex numbers that form a seamless, singularity-free representation of body orientation on S3. The Euler equations contain explicit terms describing torque from solar radiation in terms of spherical harmonics, and terms representing effects of a prescribed rate of internal friction. Numerical integrations of these equations of motion are being performed, and results will be presented. Initial tests show that internal friction without solar radiation torque leads to rotation about the maximum principal axis of inertia, as required, and solar radiation torque is expected to lead to spin-up of objects. Because the axis of maximum rotational inertia tends to be roughly coincident with the normal to the largest projected cross-sectional area, internal friction is expected to lead to reduced variation of light curve amplitudes at a given phase angle, but a large dependence of the same on phase angle. At a given phase angle, databases are generated which contain reflected intensities for comprehensive sets of equally-likely orientations, represented as unit quaternions. When projected onto three dimensions (S2) and color-coded by intensity, the set is depicted as points within a solid, semi-transparent unit sphere, within which all possible reflected intensities for an object at a given phase angle may be inspected simultaneously. Rotational sequences are represented by trajectories through the sphere. Databases are generated for each of a set of phase angles separately, forming a comprehensive dataset of reflected intensities spanning all object orientations and solar phase angles. Symmetries in the problem suggest that preferred rotation states are likely, defined relative to the object-sun direction in inertial space and relative to the maximum principal axis of inertia in the body coordinate system. Such rotation states may greatly simplify the problem of light curve interpretation by reducing the number of degrees of freedom in the problem.

Lytic and mechanical stability of clots composed of fibrin and blood vessel wall components.

PubMed

Rottenberger, Z; Komorowicz, E; Szabó, L; Bóta, A; Varga, Z; Machovich, R; Longstaff, C; Kolev, K

2013-03-01

Proteases expressed in atherosclerotic plaque lesions generate collagen fragments, release glycosaminoglycans (chondroitin sulfate [CS] and dermatan sulfate [DS]) and expose extracellular matrix (ECM) proteins (e.g. decorin) at sites of fibrin formation. Here we address the effect of these vessel wall components on the lysis of fibrin by the tissue plasminogen activator (tPA)/plasminogen system and on the mechanical stability of clots. MMP-8-digested collagen fragments, isolated CS, DS, glycosylated decorin and its core protein were used to prepare mixed matrices with fibrin (additives present at a 50-fold lower mass concentration than fibrinogen). Scanning electron microscopy (SEM) showed that the presence of ECM components resulted in a coarse fibrin structure, most pronounced for glycosylated decorin causing an increase in the median fiber diameter from 85 to 187 nm. Rheological measurements indicated that these structural alterations were coupled to decreased shear resistance (1.8-fold lower shear stress needed for gel/fluid transition of the clots containing glycosylated decorin) and rigidity (reduction of the storage modulus from 54.3 to 33.2 Pa). The lytic susceptibility of the modified fibrin structures was increased. The time to 50% lysis by plasmin was reduced approximately 2-fold for all investigated ECM components (apart from the core protein of decorin which produced a moderate reduction of the lysis time by 25%), whereas fibrin-dependent plasminogen activation by tPA was inhibited by up to 30%. ECM components compromise the chemical and mechanical stability of fibrin as a result of changes in its ultrastructure. © 2012 International Society on Thrombosis and Haemostasis.

Exchange of rotor components in functioning bacterial flagellar motor

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fukuoka, Hajime; Inoue, Yuichi; Graduate School of Life Sciences, Tohoku University, Aoba-ku, Sendai 980-8577

2010-03-26

The bacterial flagellar motor is a rotary motor driven by the electrochemical potential of a coupling ion. The interaction between a rotor and stator units is thought to generate torque. The overall structure of flagellar motor has been thought to be static, however, it was recently proved that stators are exchanged in a rotating motor. Understanding the dynamics of rotor components in functioning motor is important for the clarifying of working mechanism of bacterial flagellar motor. In this study, we focused on the dynamics and the turnover of rotor components in a functioning flagellar motor. Expression systems for GFP-FliN, FliM-GFP,more » and GFP-FliG were constructed, and each GFP-fusion was functionally incorporated into the flagellar motor. To investigate whether the rotor components are exchanged in a rotating motor, we performed fluorescence recovery after photobleaching experiments using total internal reflection fluorescence microscopy. After photobleaching, in a tethered cell producing GFP-FliN or FliM-GFP, the recovery of fluorescence at the rotational center was observed. However, in a cell producing GFP-FliG, no recovery of fluorescence was observed. The transition phase of fluorescence intensity after full or partially photobleaching allowed the turnover of FliN subunits to be calculated as 0.0007 s{sup -1}, meaning that FliN would be exchanged in tens of minutes. These novel findings indicate that a bacterial flagellar motor is not a static structure even in functioning state. This is the first report for the exchange of rotor components in a functioning bacterial flagellar motor.« less

Noise isolation system for high-speed circuits

DOEpatents

McNeilly, D.R.

1983-12-29

A noise isolation circuit is provided that consists of a dual function bypass which confines high-speed switching noise to the component or circuit which generates it and isolates the component or circuit from high-frequency noise transients which may be present on the ground and power supply busses. A local circuit ground is provided which is coupled to the system ground by sufficient impedance to force the dissipation of the noise signal in the local circuit or component generating the noise. The dual function bypass network couples high-frequency noise signals generated in the local component or circuit through a capacitor to the local ground while isolating the component or circuit from noise signals which may be present on the power supply busses or system ground. The network is an effective noise isolating system and is applicable to both high-speed analog and digital circuits.

Noise isolation system for high-speed circuits

DOEpatents

McNeilly, David R.

1986-01-01

A noise isolation circuit is provided that consists of a dual function bypass which confines high-speed switching noise to the component or circuit which generates it and isolates the component or circuit from high-frequency noise transients which may be present on the ground and power supply busses. A local circuit ground is provided which is coupled to the system ground by sufficient impedance to force the dissipation of the noise signal in the local circuit or component generating the noise. The dual function bypass network couples high-frequency noise signals generated in the local component or circuit through a capacitor to the local ground while isolating the component or circuit from noise signals which may be present on the power supply busses or system ground. The network is an effective noise isolating system and is applicable to both high-speed analog and digital circuits.

Influence of Powder Characteristics on Formation of Porosity in Additive Manufacturing of Ti-6Al-4V Components

NASA Astrophysics Data System (ADS)

Iebba, Maurizio; Astarita, Antonello; Mistretta, Daniela; Colonna, Ivano; Liberini, Mariacira; Scherillo, Fabio; Pirozzi, Carmine; Borrelli, Rosario; Franchitti, Stefania; Squillace, Antonino

2017-08-01

This paper aims to study the genesis of defects in titanium components made through two different additive manufacturing technologies: selective laser melting and electron beam melting. In particular, we focussed on the influence of the powders used on the formation of porosities and cavities in the manufactured components. A detailed experimental campaign was carried out to characterize the components made through the two additive manufacturing techniques aforementioned and the powders used in the process. It was found that some defects of the final components can be attributed to internal porosities of the powders used in the manufacturing process. These internal porosities are a consequence of the gas atomization process used for the production of the powders themselves. Therefore, the importance of using tailored powders, free from porosities, in order to manufacture components with high mechanical properties is highlighted.

Piston Ring Pressure Distribution

NASA Technical Reports Server (NTRS)

Kuhn, M.

1943-01-01

The discovery and introduction of the internal combustion engine has resulted in a very rapid development in machines utilizing the action of a piston. Design has been limited by the internal components of the engine, which has been subjected to ever increasing thermal and mechanical stresses, Of these internal engine components, the piston and piston rings are of particular importance and the momentary position of engine development is not seldom dependent upon the development of both of the components, The piston ring is a well-known component and has been used in its present shape in the steam engine of the last century, Corresponding to its importance, the piston ring has been a rich field for creative activity and it is noteworthy that in spite of this the ring has maintained its shape through the many years. From the many and complicated designs which have been suggested as a packing between piston and cylinder wall hardly one suggestion has remained which does not resemble the original design of cast iron rectangular ring.

Forward modeling of gravity data using geostatistically generated subsurface density variations

USGS Publications Warehouse

Phelps, Geoffrey

2016-01-01

Using geostatistical models of density variations in the subsurface, constrained by geologic data, forward models of gravity anomalies can be generated by discretizing the subsurface and calculating the cumulative effect of each cell (pixel). The results of such stochastically generated forward gravity anomalies can be compared with the observed gravity anomalies to find density models that match the observed data. These models have an advantage over forward gravity anomalies generated using polygonal bodies of homogeneous density because generating numerous realizations explores a larger region of the solution space. The stochastic modeling can be thought of as dividing the forward model into two components: that due to the shape of each geologic unit and that due to the heterogeneous distribution of density within each geologic unit. The modeling demonstrates that the internally heterogeneous distribution of density within each geologic unit can contribute significantly to the resulting calculated forward gravity anomaly. Furthermore, the stochastic models match observed statistical properties of geologic units, the solution space is more broadly explored by producing a suite of successful models, and the likelihood of a particular conceptual geologic model can be compared. The Vaca Fault near Travis Air Force Base, California, can be successfully modeled as a normal or strike-slip fault, with the normal fault model being slightly more probable. It can also be modeled as a reverse fault, although this structural geologic configuration is highly unlikely given the realizations we explored.

EPIC : expedited processing at international crossings : evaluation final report

DOT National Transportation Integrated Search

1998-09-01

This executive summary presents an overview of the Expedited Processing at International Crossings (EPIC) Field Operational Test (FOT). The EPIC focus was on the commercial vehicle transport component of international border crossings at the Nogales,...

A laser scanning system for metrology and viewing in ITER

DOE Office of Scientific and Technical Information (OSTI.GOV)

Spampinato, P.T.; Barry, R.E.; Menon, M.M.

1996-05-01

The construction and operation of a next-generation fusion reactor will require metrology to achieve and verify precise alignment of plasma-facing components and inspection in the reactor vessel. The system must be compatible with the vessel environment of high gamma radiation (10{sup 4} Gy/h), ultra-high-vacuum (10{sup {minus}8} torr), and elevated temperature (200 C). The high radiation requires that the system be remotely deployed. A coherent frequency modulated laser radar-based system will be integrated with a remotely operated deployment mechanism to meet these requirements. The metrology/viewing system consists of a compact laser transceiver optics module which is linked through fiber optics tomore » the laser source and imaging units that are located outside of a biological shield. The deployment mechanism will be a mast-like positioning system. Radiation-damage tests will be conducted on critical sensor components at Oak Ridge National Laboratory to determine threshold damage levels and effects on data transmission. This paper identifies the requirements for International Thermonuclear Experimental Reactor metrology and viewing and describes a remotely operated precision ranging and surface mapping system.« less

Properties and Performance Attributes of Novel Co-Extruded Polyolefin Battery Separator Materials. Part 1; Mechanical Properties

NASA Technical Reports Server (NTRS)

Baldwin, Richard S.; Guzik, Monica; Skierski, Michael

2011-01-01

As NASA prepares for its next era of manned spaceflight missions, advanced energy storage technologies are being developed and evaluated to address future mission needs and technical requirements and to provide new mission-enabling technologies. Cell-level components for advanced lithium-ion batteries possessing higher energy, more reliable performance and enhanced, inherent safety characteristics are actively under development within the NASA infrastructure. A key component for safe and reliable cell performance is the cell separator, which separates the two energetic electrodes and functions to prevent the occurrence of an internal short-circuit while enabling ionic transport. Recently, a new generation of co-extruded separator films has been developed by ExxonMobil Chemical and introduced into their battery separator product portfolio. Several grades of this new separator material have been evaluated with respect to dynamic mechanical properties and safety-related performance attributes. This paper presents the results of these evaluations in comparison to a current state-ofthe-practice separator material. The results are discussed with respect to potential opportunities to enhance the inherent safety characteristics and reliability of future, advanced lithium-ion cell chemistries.

Development of A General Principle Solution Forisoagrinet Compliant Networking System Components in Animal Husbandry

NASA Astrophysics Data System (ADS)

Kuhlmann, Arne; Herd, Daniel; Röβler, Benjamin; Gallmann, Eva; Jungbluth, Thomas

In pig production software and electronic systems are widely used for process control and management. Unfortunately most devices on farms are proprietary solutions and autonomically working. To unify data communication of devices in agricultural husbandry, the international standard ISOagriNET (ISO 17532:2007) was developed. It defines data formats and exchange protocols, to link up devices like climate controls, feeding systems and sensors, but also management software. The aim of the research project, "Information and Data Collection in Livestock Systems" is to develop an ISOagriNET compliant IT system, a so called Farming Cell. It integrates all electronic components to acquire the available data and information for pig fattening. That way, an additional benefit to humans, animals and the environment regarding process control and documentation, can be generated. Developing the Farming Cell is very complex; in detail it is very difficult and long-winded to integrate hardware and software by various vendors into an ISOagriNET compliant IT system. This ISOagriNET prototype shows as a test environment the potential of this new standard.

75 FR 8399 - In the Matter of Certain Mobile Communications and Computer Devices and Components Thereof...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-24

... Communications and Computer Devices and Components Thereof; Notice of Investigation AGENCY: U.S. International... States after importation of certain mobile communications and computer devices and components thereof by... importation of certain mobile communications or computer devices or components thereof that infringe one or...

77 FR 22803 - Certain Audiovisual Components and Products Containing the Same; Institution of Investigation...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-17

... INTERNATIONAL TRADE COMMISSION [Inv. No. 337-TA-837] Certain Audiovisual Components and Products... importation of certain audiovisual components and products containing the same by reason of infringement of... importation, or the sale within the United States after importation of certain audiovisual components and...

Controlled Microfluidic Assembly and Functionalization of Complex Biomolecules

DTIC Science & Technology

2017-10-27

Name: The 15th International Conference on Micro and Nanotechnology for Power Generation and Energy Conversion Applications Conference Location...Paper or Presentation Conference Name: The 15th International Conference on Micro and Nanotechnology for Power Generation and Energy Conversion

Effective Techniques for Augmenting Heat Transfer: An Application of Entropy Generation Minimization Principles.

DTIC Science & Technology

1980-12-01

augmentation techniques, entropy generation, irreversibility, exergy . 20. ABSTRACT (Continue on rovers. side If necessary and Identify by block number...35 3.5 Internally finned tubes ...... ................. .. 37 3.6 Internally roughened tubes ..... ............... . 41 3.7 Other heat transfer...irreversibility and entropy generation as fundamental criterion for evaluating and, eventually, minimizing the waste of usable energy ( exergy ) in energy

Genotype differences in anxiety and fear learning and memory of WT and ApoE4 mice associated with enhanced generation of hippocampal reactive oxygen species.

PubMed

Villasana, Laura E; Weber, Sydney; Akinyeke, Tunde; Raber, Jacob

2016-09-01

Apolipoprotein E (apoE), involved in cholesterol and lipid metabolism, also influences cognitive function and injury repair. In humans, apoE is expressed in three isoforms. E4 is a risk factor for age-related cognitive decline and Alzheimer's disease, particularly in women. E4 might also be a risk factor for developing behavioral and cognitive changes following (56) Fe irradiation, a component of the space environment astronauts are exposed to during missions. These changes might be related to enhanced generation of reactive oxygen species (ROS). In this study, we compared the behavioral and cognitive performance of sham-irradiated and irradiated wild-type (WT) mice and mice expressing the human E3 or E4 isoforms, and assessed the generation of ROS in hippocampal slices from these mice. E4 mice had greater anxiety-like and conditioned fear behaviors than WT mice, and these genotype differences were associated with greater levels of ROS in E4 than WT mice. The greater generation of ROS in the hippocampus of E4 than WT mice might contribute to their higher anxiety levels and enhanced fear conditioning. In E4, but not WT, mice, phorbol-12-myristate-13-acetate-treated hippocampal slices showed more dihydroxy ethidium oxidation in sham-irradiated than irradiated mice and hippocampal heme oxygenase-1 levels were higher in irradiated than sham-irradiated E4 mice. Mice with apolipoprotein E4 (E4), a risk factor for Alzheimer's disease, have greater anxiety-like and conditioned fear behaviors than wild-type (WT) mice. Generation of reactive oxygen species (ROS, in red) 3 months following (56) Fe irradiation, a component of the space environment astronauts are exposed to, is more pronounced in the hippocampus of E4 than WT mice. In E4, but not WT, mice, hippocampal levels of the oxidative stress-relevant marker heme oxygenase-1 are higher in irradiated than sham-irradiated E4 mice. © 2016 International Society for Neurochemistry.

Relative influences of the metocean forcings on the drifting ice pack and estimation of internal ice stress gradients in the Labrador Sea

NASA Astrophysics Data System (ADS)

Turnbull, I. D.; Torbati, R. Z.; Taylor, R. S.

2017-07-01

Understanding the relative influences of the metocean forcings on the drift of sea ice floes is a crucial component to the overall characterization of an ice environment and to developing an understanding of the factors controlling the ice dynamics. In addition, estimating the magnitude of the internal stress gradients on drifting sea ice floes generated by surrounding ice cover is important for modeling operations, informing the design of offshore structures and vessels in ice environments, and for the proper calibration of Discrete Element Models (DEM) of fields of drifting ice floes. In the spring of 2015 and 2016, four sea ice floes offshore Makkovik, Labrador were tagged with satellite-linked ice tracking buoys along with one satellite-linked weather station on each floe to transmit wind speed and direction. Twenty satellite-linked Lagrangian surface ocean current tracking buoys were also deployed in the open water adjacent to the targeted ice floes. In this paper, the dynamics of the four ice floes are explored in terms of the relative proportions which were forced by the wind, current, sea surface topography, Coriolis, and internal stress gradients. The internal ice stress gradients are calculated as residuals between the observed accelerations of the floes as measured by the tracking buoys and the sums of the other metocean forcings. Results show that internal ice stress gradients accounted for up to 50% of the observed forcing on the floes, and may have reached up to around 0.19 kPa.

Migration in far west Nepal: intergenerational linkages between internal and international migration of rural-to-urban migrants.

PubMed

Poertner, Ephraim; Junginger, Mathias; Müller-Böker, Ulrike

2011-01-01

In Nepal, international labor migration to India and overseas, as well as internal migration to the rural Nepalese lowlands, is of high socioeconomic significance. Scholarly debates about migration in Nepal have gradually shifted from an economic to a more holistic perspective, also incorporating social dimensions. However, little evidence has been generated about internal migration to urban destinations and the potential linkages between international and internal migration. This article draws on Bourdieu's “Theory of Practice” and sees migration as a social practice. Accordingly, migration practice is regarded as a strategy social agents apply to increase or transfer capitals and ultimately secure or improve their social position. Evidence for this argument is based on a qualitative case study of rural to urban migrants in Far West Nepal conducted in July and August 2009. The study at hand addresses linkages between internal and international migration practices and provides insight about a social stratum that is often neglected in migration research: the middle class and, more precisely, government employees. The authors show that social relations are crucial for channeling internal migration to a specific destination. Furthermore, they unveil how internal migration is connected to the international labor migration of former generations. Finally, the authors examine how migration strategies adopted over generations create multi-local social networks rooted in the family's place of origin.

A method for calculating strut and splitter plate noise in exit ducts: Theory and verification

NASA Technical Reports Server (NTRS)

Fink, M. R.

1978-01-01

Portions of a four-year analytical and experimental investigation relative to noise radiation from engine internal components in turbulent flow are summarized. Spectra measured for such airfoils over a range of chord, thickness ratio, flow velocity, and turbulence level were compared with predictions made by an available rigorous thin-airfoil analytical method. This analysis included the effects of flow compressibility and source noncompactness. Generally good agreement was obtained. This noise calculation method for isolated airfoils in turbulent flow was combined with a method for calculating transmission of sound through a subsonic exit duct and with an empirical far-field directivity shape. These three elements were checked separately and were individually shown to give close agreement with data. This combination provides a method for predicting engine internally generated aft-radiated noise from radial struts and stators, and annular splitter rings. Calculated sound power spectra, directivity, and acoustic pressure spectra were compared with the best available data. These data were for noise caused by a fan exit duct annular splitter ring, larger-chord stator blades, and turbine exit struts.

International Space Station (ISS)

NASA Image and Video Library

2006-12-09

Against a black night sky, the Space Shuttle Discovery and its seven-member crew head toward Earth-orbit and a scheduled linkup with the International Space Station (ISS). Liftoff from the Kennedy Space Center's launch pad 39B occurred at 8:47 p.m. (EST) on Dec. 9, 2006 in what was the first evening shuttle launch since 2002. The primary mission objective was to deliver and install the P5 truss element. The P5 installation was conducted during the first of three space walks, and involved use of both the shuttle and station’s robotic arms. The remainder of the mission included a major reconfiguration and activation of the ISS electrical and thermal control systems, as well as delivery of Zvezda Service Module debris panels, which will increase ISS protection from potential impacts of micro-meteorites and orbital debris. Two major payloads developed at the Marshall Space Flight Center (MSFC) were also delivered to the Station. The Lab-On-A Chip Application Development Portable Test System (LOCAD-PTS) and the Water Delivery System, a vital component of the Station’s Oxygen Generation System.

Landing pressure loads of the 140A/B space shuttle orbiter (model 43-0) determined in the Rockwell International low speed wind tunnel (OA69), volume 1. [wind tunnel tests

NASA Technical Reports Server (NTRS)

Soard, T. L.

1975-01-01

Wind tunnel tests of a 0.0405 scale model of the -1404A/B configuration of the Space Shuttle Vehicle Orbiter are presented. Pressure loads data were obtained from the orbiter in the landing configuration in the presence of the ground for structural strength analysis. This was accomplished by locating as many as 30 static pressure bugs at various locations on external model surfaces as each configuration was tested. A complete pressure loads survey was generated for each configuration by combining data from all bug locations, and these loads are described for the fuselage, wing, vertical tail, and landing gear doors. Aerodynamic force data was measured by a six component internal strain gage balance. This data was recorded to correct model angles of attack and sideslip for sting and balance deflections and to determine the aerodynamic effects of landing gear extension. All testing was conducted at a Mach number of 0.165 and a Reynolds number of 1.2 million per foot. Photographs of test configurations are shown.

Relevant Scatterers Characterization in SAR Images

NASA Astrophysics Data System (ADS)

Chaabouni, Houda; Datcu, Mihai

2006-11-01

Recognizing scenes in a single look meter resolution Synthetic Aperture Radar (SAR) images, requires the capability to identify relevant signal signatures in condition of variable image acquisition geometry, arbitrary objects poses and configurations. Among the methods to detect relevant scatterers in SAR images, we can mention the internal coherence. The SAR spectrum splitted in azimuth generates a series of images which preserve high coherence only for particular object scattering. The detection of relevant scatterers can be done by correlation study or Independent Component Analysis (ICA) methods. The present article deals with the state of the art for SAR internal correlation analysis and proposes further extensions using elements of inference based on information theory applied to complex valued signals. The set of azimuth looks images is analyzed using mutual information measures and an equivalent channel capacity is derived. The localization of the "target" requires analysis in a small image window, thus resulting in imprecise estimation of the second order statistics of the signal. For a better precision, a Hausdorff measure is introduced. The method is applied to detect and characterize relevant objects in urban areas.

Internal Electrostatic Discharge Monitor - IESDM

NASA Technical Reports Server (NTRS)

Kim, Wousik; Goebel, Dan M.; Jun, Insoo; Garrett, Henry B.

2011-01-01

A document discusses an innovation designed to effectively monitor dielectric charging in spacecraft components to measure the potential for discharge in order to prevent damage from internal electrostatic discharge (IESD). High-energy electrons penetrate the structural materials and shielding of a spacecraft and then stop inside dielectrics and keep accumulating. Those deposited charges generate an electric field. If the electric field becomes higher than the breakdown threshold (approx. =2 x 10(exp 5) V/cm), discharge occurs. This monitor measures potentials as a function of dielectric depth. Differentiation of potential with respect to the depth yields electric field. Direct measurement of the depth profile of the potential in a dielectric makes real-time electronic field evaluation possible without simulations. The IESDM has been designed to emulate a multi-layer circuit board, to insert very thin metallic layers between the dielectric layers. The conductors serve as diagnostic monitoring locations to measure the deposited electron-charge and the charge dynamics. Measurement of the time-dependent potential of the metal layers provides information on the amount of charge deposited in the dielectrics and the movement of that charge with time (dynamics).

Dimensional approaches to psychiatric classification: refining the research agenda for DSM-V: an introduction.

PubMed

Regier, Darrel A

2007-01-01

The American Psychiatric Association (APA) will publish the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-V), in 2012. This paper reviews the extended, multi-faceted research planning preparations that APA has undertaken, several in collaboration with the World Health Organization and the U.S. National Institutes of Health, to assess the current state of diagnosis-relevant research and to generate short- and long-term recommendations for research needed to enrich DSM-V and future psychiatric classifications. This research review and planning process has underscored widespread interest among nosologists in the US and globally regarding the potential benefits for research and clinical practice of incorporating a dimensional component into the existing categorical, or binary, classification system in the DSM. Toward this end, the APA and its partners convened an international conference in July 2006 to critically appraise the use of dimensional constructs in psychiatric diagnostic systems. Resultant papers appear in this issue of International Journal of Methods in Psychiatric Research and in a forthcoming monograph to be published by APA. Copyright (c) 2007 John Wiley & Sons, Ltd.

Failure analysis of pinch-torsion tests as a thermal runaway risk evaluation method of Li-ion cells

NASA Astrophysics Data System (ADS)

Xia, Yuzhi; Li, Tianlei; Ren, Fei; Gao, Yanfei; Wang, Hsin

2014-11-01

Recently a pinch-torsion test is developed for safety testing of Li-ion batteries. It has been demonstrated that this test can generate small internal short-circuit spots in the separator in a controllable and repeatable manner. In the current research, the failure mechanism is examined by numerical simulations and comparisons to experimental observations. Finite element models are developed to evaluate the deformation of the separators under both pure pinch and pinch-torsion loading conditions. It is discovered that the addition of the torsion component significantly increased the maximum first principal strain, which is believed to induce the internal short circuit. In addition, the applied load in the pinch-torsion test is significantly less than in the pure pinch test, thus dramatically improving the applicability of this method to ultra-thick batteries which otherwise require heavy load in excess of machine capability. It is further found that the separator failure is achieved in the early stage of torsion (within a few degree of rotation). Effect of coefficient of friction on the maximum first principal strain is also examined.

Evaluation of Aspergillus PCR protocols for testing serum specimens.

PubMed

White, P Lewis; Mengoli, Carlo; Bretagne, Stéphane; Cuenca-Estrella, Manuel; Finnstrom, Niklas; Klingspor, Lena; Melchers, Willem J G; McCulloch, Elaine; Barnes, Rosemary A; Donnelly, J Peter; Loeffler, Juergen

2011-11-01

A panel of human serum samples spiked with various amounts of Aspergillus fumigatus genomic DNA was distributed to 23 centers within the European Aspergillus PCR Initiative to determine analytical performance of PCR. Information regarding specific methodological components and PCR performance was requested. The information provided was made anonymous, and meta-regression analysis was performed to determine any procedural factors that significantly altered PCR performance. Ninety-seven percent of protocols were able to detect a threshold of 10 genomes/ml on at least one occasion, with 83% of protocols reproducibly detecting this concentration. Sensitivity and specificity were 86.1% and 93.6%, respectively. Positive associations between sensitivity and the use of larger sample volumes, an internal control PCR, and PCR targeting the internal transcribed spacer (ITS) region were shown. Negative associations between sensitivity and the use of larger elution volumes (≥100 μl) and PCR targeting the mitochondrial genes were demonstrated. Most Aspergillus PCR protocols used to test serum generate satisfactory analytical performance. Testing serum requires less standardization, and the specific recommendations shown in this article will only improve performance.

Evaluation of Aspergillus PCR Protocols for Testing Serum Specimens▿†

PubMed Central

White, P. Lewis; Mengoli, Carlo; Bretagne, Stéphane; Cuenca-Estrella, Manuel; Finnstrom, Niklas; Klingspor, Lena; Melchers, Willem J. G.; McCulloch, Elaine; Barnes, Rosemary A.; Donnelly, J. Peter; Loeffler, Juergen

2011-01-01

A panel of human serum samples spiked with various amounts of Aspergillus fumigatus genomic DNA was distributed to 23 centers within the European Aspergillus PCR Initiative to determine analytical performance of PCR. Information regarding specific methodological components and PCR performance was requested. The information provided was made anonymous, and meta-regression analysis was performed to determine any procedural factors that significantly altered PCR performance. Ninety-seven percent of protocols were able to detect a threshold of 10 genomes/ml on at least one occasion, with 83% of protocols reproducibly detecting this concentration. Sensitivity and specificity were 86.1% and 93.6%, respectively. Positive associations between sensitivity and the use of larger sample volumes, an internal control PCR, and PCR targeting the internal transcribed spacer (ITS) region were shown. Negative associations between sensitivity and the use of larger elution volumes (≥100 μl) and PCR targeting the mitochondrial genes were demonstrated. Most Aspergillus PCR protocols used to test serum generate satisfactory analytical performance. Testing serum requires less standardization, and the specific recommendations shown in this article will only improve performance. PMID:21940479

The Role of International Research Collaboration in Enhancing Global Presence of an Institution

ERIC Educational Resources Information Center

Ao, Fiona Ka Wa

2012-01-01

In recent decades, higher education institutions have steadily increased their international involvement in response to globalization. High-level research is generally a key component in efforts to increase international visibility (Armstrong, 2007). International research collaborations are perceived to be an important way to enhance global…

Nonlinear viscous higher harmonics generation due to incident and reflecting internal wave beam collision

NASA Astrophysics Data System (ADS)

Aksu, Anil A.

2017-09-01

In this paper, we have considered the non-linear effects arising due to the collision of incident and reflected internal wave beams. It has already been shown analytically [Tabaei et al., "Nonlinear effects in reflecting and colliding internal wave beams," J. Fluid Mech. 526, 217-243 (2005)] and numerically [Rodenborn et al., "Harmonic generation by reflecting internal waves," Phys. Fluids 23, 026601 (2011)] that the internal wave beam collision generates the higher harmonics and mean flow in a linear stratification. In this paper, similar to previous analytical work, small amplitude wave theory is employed; however, it is formulated from energetics perspective which allows considering internal wave beams as the product of slowly varying amplitude and fast complex exponential. As a result, the mean energy propagation equation for the second harmonic wave is obtained. Finally, a similar dependence on the angle of incidence is obtained for the non-linear energy transfer to the second harmonic with previous analyses. A possible physical mechanism for this angle dependence on the second harmonic generation is also discussed here. In addition to previous studies, the viscous effects are also included in the mean energy propagation equation for the incident, the reflecting, and the second harmonic waves. Moreover, even though the mean flow obtained here is only confined to the interaction region, it is also affected by viscosity via the decay in the incident and the reflecting internal wave beams. Furthermore, a framework for the non-linear harmonic generation in non-linear stratification is also proposed here.

System and method for generating steady state confining current for a toroidal plasma fusion reactor

DOEpatents

Fisch, Nathaniel J.

1981-01-01

A system for generating steady state confining current for a toroidal plasma fusion reactor providing steady-state generation of the thermonuclear power. A dense, hot toroidal plasma is initially prepared with a confining magnetic field with toroidal and poloidal components. Continuous wave RF energy is injected into said plasma to establish a spectrum of traveling waves in the plasma, where the traveling waves have momentum components substantially either all parallel, or all anti-parallel to the confining magnetic field. The injected RF energy is phased to couple to said traveling waves with both a phase velocity component and a wave momentum component in the direction of the plasma traveling wave components. The injected RF energy has a predetermined spectrum selected so that said traveling waves couple to plasma electrons having velocities in a predetermined range .DELTA.. The velocities in the range are substantially greater than the thermal electron velocity of the plasma. In addition, the range is sufficiently broad to produce a raised plateau having width .DELTA. in the plasma electron velocity distribution so that the plateau electrons provide steady-state current to generate a poloidal magnetic field component sufficient for confining the plasma. In steady state operation of the fusion reactor, the fusion power density in the plasma exceeds the power dissipated in the plasma.

System and method for generating steady state confining current for a toroidal plasma fusion reactor

DOEpatents

Bers, Abraham

1981-01-01

A system for generating steady state confining current for a toroidal plasma fusion reactor providing steady-state generation of the thermonuclear power. A dense, hot toroidal plasma is initially prepared with a confining magnetic field with toroidal and poloidal components. Continuous wave RF energy is injected into said plasma to estalish a spectrum of traveling waves in the plasma, where the traveling waves have momentum components substantially either all parallel, or all anti-parallel to the confining magnetic field. The injected RF energy is phased to couple to said traveling waves with both a phase velocity component and a wave momentum component in the direction of the plasma traveling wave components. The injected RF energy has a predetermined spectrum selected so that said traveling waves couple to plasma electrons having velocities in a predetermined range .DELTA.. The velocities in the range are substantially greater than the thermal electron velocity of the plasma. In addition, the range is sufficiently broad to produce a raised plateau having width .DELTA. in the plasma electron velocity distribution so that the plateau electrons provide steady-state current to generate a poloidal magnetic field component sufficient for confining the plasma. In steady state operation of the fusion reactor, the fusion power density in the plasma exceeds the power dissipated inthe plasma.

Correlation between audible noise and corona current generated by AC corona discharge in time and frequency domains

NASA Astrophysics Data System (ADS)

Li, Xuebao; Wang, Jing; Li, Yinfei; Zhang, Qian; Lu, Tiebing; Cui, Xiang

2018-06-01

Corona-generated audible noise is induced by the collisions between space charges and air molecules. It has been proven that there is a close correlation between audible noise and corona current from DC corona discharge. Analysis on the correlation between audible noise and corona current can promote the cognition of the generation mechanism of corona discharge. In this paper, time-domain waveforms of AC corona-generated audible noise and corona current are measured simultaneously. The one-to-one relationship between sound pressure pulses and corona current pulses can be found and is used to remove the interferences from background noise. After the interferences are removed, the linear correlated relationships between sound pressure pulse amplitude and corona current pulse amplitude are obtained through statistical analysis. Besides, frequency components at the harmonics of power frequency (50 Hz) can be found both in the frequency spectrums of audible noise and corona current through frequency analysis. Furthermore, the self-correlation relationships between harmonic components below 400 Hz with the 50 Hz component are analyzed for audible noise and corona current and corresponding empirical formulas are proposed to calculate the harmonic components based on the 50 Hz component. Finally, based on the AC corona discharge process and generation mechanism of audible noise and corona current, the correlation between audible noise and corona current in time domain and frequency domain are interpreted qualitatively. Besides, with the aid of analytical expressions of periodic square waves, sound pressure pulses, and corona current pulses, the modulation effects from the AC voltage on the pulse trains are used to interpret the generation of the harmonic components of audible noise and corona current.

The Overgrid Interface for Computational Simulations on Overset Grids

NASA Technical Reports Server (NTRS)

Chan, William M.; Kwak, Dochan (Technical Monitor)

2002-01-01

Computational simulations using overset grids typically involve multiple steps and a variety of software modules. A graphical interface called OVERGRID has been specially designed for such purposes. Data required and created by the different steps include geometry, grids, domain connectivity information and flow solver input parameters. The interface provides a unified environment for the visualization, processing, generation and diagnosis of such data. General modules are available for the manipulation of structured grids and unstructured surface triangulations. Modules more specific for the overset approach include surface curve generators, hyperbolic and algebraic surface grid generators, a hyperbolic volume grid generator, Cartesian box grid generators, and domain connectivity: pre-processing tools. An interface provides automatic selection and viewing of flow solver boundary conditions, and various other flow solver inputs. For problems involving multiple components in relative motion, a module is available to build the component/grid relationships and to prescribe and animate the dynamics of the different components.

Timing Actions to Avoid Refractoriness: A Simple Solution for Streaming Sensory Signals

PubMed Central

Nogueira, Javier; Caputi, Ángel Ariel

2011-01-01

Segmenting self- from allo-generated signals is crucial for active sensory processing. We report a dynamic filter used by South American pulse electric fish to distinguish active electro-sensory signals carried by their own electric discharges from other concomitant electrical stimuli (i.e. communication signals). The filter has a sensory component, consisting of an onset type central electro-sensory neuron, and a motor component, consisting of a change in the fish's discharge rate when allo-generated electrical events occur in temporal proximity to the fish's own discharge. We investigated the sensory component of the filter by in vitro mimicking synaptic inputs occurring during behavioral responses to allo-generated interfering signals. We found that active control of the discharge enhances self-generated over allo-generated responses by forcing allo-generated signals into a central refractory period. This hypothesis was confirmed by field potential recordings in freely discharging fish. Similar sensory-motor mechanisms may also contribute to signal segmentation in other sensory systems. PMID:21789228

Electrogenesis in the lower Metazoa and implications for neuronal integration

PubMed Central

Meech, Robert W.

2015-01-01

Electrogenic communication appears to have evolved independently in a variety of animal and plant lineages. Considered here are metazoan cells as disparate as the loose three-dimensional parenchyma of glass sponges, the two-dimensional epithelial sheets of hydrozoan jellyfish and the egg cell membranes of the ctenophore Beroe ovata, all of which are capable of generating electrical impulses. Neuronal electrogenesis may have evolved independently in ctenophores and cnidarians but the dearth of electrophysiological data relating to ctenophore nerves means that our attention is focused on the Cnidaria, whose nervous systems have been the subject of extensive study. The aim here is to show how their active and passive neuronal properties interact to give integrated behaviour. Neuronal electrogenesis, goes beyond simply relaying ‘states of excitement’ and utilizes the equivalent of a set of basic electrical ‘apps’ to integrate incoming sensory information with internally generated pacemaker activity. A small number of membrane-based processes make up these analogue applications. Passive components include the decremental spread of current determined by cellular anatomy; active components include ion channels specified by their selectivity and voltage dependence. A recurring theme is the role of inactivating potassium channels in regulating performance. Although different aspects of cnidarian behaviour are controlled by separate neuronal systems, integrated responses and coordinated movements depend on interactions between them. Integrative interactions discussed here include those between feeding and swimming, between tentacle contraction and swimming and between slow and fast swimming in the hydrozoan jellyfish Aglantha digitale. PMID:25696817

What types of Level 3 products are available?

Atmospheric Science Data Center

2016-02-19

The Level 3 Component Global Georectified Radiation Product (CGGRP), Component Global Land Surface Product (CGLS), Component Global Aerosol Product (CGAS), and Component Global Albedo Product (CGAL) are generated for daily, monthly, quarterly,...

Characterizing the mechanics of cultured cell monolayers

PubMed Central

Peter, Loic; Bellis, Julien; Baum, Buzz; Kabla, Alexandre J.; Charras, Guillaume T.

2012-01-01

One-cell-thick monolayers are the simplest tissues in multicellular organisms, yet they fulfill critical roles in development and normal physiology. In early development, embryonic morphogenesis results largely from monolayer rearrangement and deformation due to internally generated forces. Later, monolayers act as physical barriers separating the internal environment from the exterior and must withstand externally applied forces. Though resisting and generating mechanical forces is an essential part of monolayer function, simple experimental methods to characterize monolayer mechanical properties are lacking. Here, we describe a system for tensile testing of freely suspended cultured monolayers that enables the examination of their mechanical behavior at multi-, uni-, and subcellular scales. Using this system, we provide measurements of monolayer elasticity and show that this is two orders of magnitude larger than the elasticity of their isolated cellular components. Monolayers could withstand more than a doubling in length before failing through rupture of intercellular junctions. Measurement of stress at fracture enabled a first estimation of the average force needed to separate cells within truly mature monolayers, approximately ninefold larger than measured in pairs of isolated cells. As in single cells, monolayer mechanical properties were strongly dependent on the integrity of the actin cytoskeleton, myosin, and intercellular adhesions interfacing adjacent cells. High magnification imaging revealed that keratin filaments became progressively stretched during extension, suggesting they participate in monolayer mechanics. This multiscale study of monolayer response to deformation enabled by our device provides the first quantitative investigation of the link between monolayer biology and mechanics. PMID:22991459

Fluorine Variations in the Globular Cluster NGC 6656 (M22): Implications for Internal Enrichment Timescales

NASA Astrophysics Data System (ADS)

D'Orazi, Valentina; Lucatello, Sara; Lugaro, Maria; Gratton, Raffaele G.; Angelou, George; Bragaglia, Angela; Carretta, Eugenio; Alves-Brito, Alan; Ivans, Inese I.; Masseron, Thomas; Mucciarelli, Alessio

2013-01-01

Observed chemical (anti)correlations in proton-capture elements among globular cluster stars are presently recognized as the signature of self-enrichment from now extinct, previous generations of stars. This defines the multiple population scenario. Since fluorine is also affected by proton captures, determining its abundance in globular clusters provides new and complementary clues regarding the nature of these previous generations and supplies strong observational constraints to the chemical enrichment timescales. In this paper, we present our results on near-infrared CRIRES spectroscopic observations of six cool giant stars in NGC 6656 (M22): the main objective is to derive the F content and its internal variation in this peculiar cluster, which exhibits significant changes in both light- and heavy-element abundances. Across our sample, we detected F variations beyond the measurement uncertainties and found that the F abundances are positively correlated with O and anticorrelated with Na, as expected according to the multiple population framework. Furthermore, our observations reveal an increase in the F content between the two different sub-groups, s-process rich and s-process poor, hosted within M22. The comparison with theoretical models suggests that asymptotic giant stars with masses between 4 and 5 M ⊙ are responsible for the observed chemical pattern, confirming evidence from previous works: the difference in age between the two sub-components in M22 must be not larger than a few hundred Myr. Based on observations taken with ESO telescopes under program 087.0319(A).

Fluorescein thiocarbamyl amino acids as internal standards for migration time correction in capillary sieving electrophoresis

PubMed Central

Pugsley, Haley R.; Swearingen, Kristian E.; Dovichi, Norman J.

2009-01-01

A number of algorithms have been developed to correct for migration time drift in capillary electrophoresis. Those algorithms require identification of common components in each run. However, not all components may be present or resolved in separations of complex samples, which can confound attempts for alignment. This paper reports the use of fluorescein thiocarbamyl derivatives of amino acids as internal standards for alignment of 3-(2-furoyl)quinoline-2-carboxaldehyde (FQ)-labeled proteins in capillary sieving electrophoresis. The fluorescein thiocarbamyl derivative of aspartic acid migrates before FQ-labeled proteins and the fluorescein thiocarbamyl derivative of arginine migrates after the FQ-labeled proteins. These compounds were used as internal standards to correct for variations in migration time over a two-week period in the separation of a cellular homogenate. The experimental conditions were deliberately manipulated by varying electric field and sample preparation conditions. Three components of the homogenate were used to evaluate the alignment efficiency. Before alignment, the average relative standard deviation in migration time for these components was 13.3%. After alignment, the average relative standard deviation in migration time for these components was reduced to 0.5%. PMID:19249052

A calibration rig for multi-component internal strain gauge balance using the new design-of-experiment (DOE) approach

NASA Astrophysics Data System (ADS)

Nouri, N. M.; Mostafapour, K.; Kamran, M.

2018-02-01

In a closed water-tunnel circuit, the multi-component strain gauge force and moment sensor (also known as balance) are generally used to measure hydrodynamic forces and moments acting on scaled models. These balances are periodically calibrated by static loading. Their performance and accuracy depend significantly on the rig and the method of calibration. In this research, a new calibration rig was designed and constructed to calibrate multi-component internal strain gauge balances. The calibration rig has six degrees of freedom and six different component-loading structures that can be applied separately and synchronously. The system was designed based on the applicability of formal experimental design techniques, using gravity for balance loading and balance positioning and alignment relative to gravity. To evaluate the calibration rig, a six-component internal balance developed by Iran University of Science and Technology was calibrated using response surface methodology. According to the results, calibration rig met all design criteria. This rig provides the means by which various methods of formal experimental design techniques can be implemented. The simplicity of the rig saves time and money in the design of experiments and in balance calibration while simultaneously increasing the accuracy of these activities.

Report to the International Global Atmospheric Chemistry Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Reisdorf, Jill; Wiedinmyer, Christine

IGAC’s mission is to facilitate atmospheric chemistry research towards a sustainable world. This is achieved through IGAC’s three focal activities: fostering community, building capacity, and providing leadership. A key component to achieving IGAC’s mission is its developing early career program. These scientists join an international network early in their career that puts the cogs in motion to further facilitate atmospheric chemistry research at an international level for years to come. IGAC’s Science Conference is a primary mechanism for IGAC to build cooperation and disseminate scientific information across its international community. The first IGAC Science Conference was held in 1993 in Eilat,more » Israel. Since then, IGAC has successfully held fourteen science conferences, consistently becoming a biennial conference starting in 2002. The biennial IGAC Science Conference is regarded as THE international conference on atmospheric chemistry and participation in the conference is typically in the range of 350-650 participants. Since 2004, IGAC has included an Early Career Scientists Program as part of the conference to foster the next generation of scientists. IGAC believes, and has seen, that by allowing scientists to form an international network of colleagues early in their career that future international collaborations in atmospheric chemistry are enhanced. The 2016 IGAC Science Conference Early Career Program consisted of numerous events throughout the week giving these scientists the opportunity to not only create a community amongst themselves, but to also engage and build relationships with senior scientists. In order to support the Early Career Scientists Program, IGAC sought funding from international, regional and local organizations to provide Travel Grants to the conference based on an assessment of both need and merit. This conference summary reports on outcomes of the 2016 IGAC Science Conference and the Early Career Program, which included early career travel grants funded by this DOE grant.« less

[Study on the resilience internal factors in a sample of Puerto Rican centenarians].

PubMed

Rosado-Medina, José J; Rodríguez-Gómez, José R; Altieri-Ramirez, Gladys

2012-01-01

Old age is a stage that is usually characterized by lost at the physiological, psychological and social level that generates much distress to individuals. However, the centenaries have been identified as an example of successful aging, within other factors, because they have adequate managed skills that help them to deal with healthy normal losses. Resilience could be one of the factors that may help the Centennials to age successfully. It is necessary more studies with Puerto Rico Centennials since we lack such investigations. This study has an expo facto design; in addition we evaluate psychometrically the Symptoms Check List 90-R (SCL-90-R). The scale of Internal Resilience Factors (EFIR), a semi structured interview and the SCL-90-R were used to identify factors associated with successful aging in the centennials. In addition we explore if there exist gender differences in internal factors of resilience within the sample. 23 Centennials, 15 men and 8 women, of different parts of Puerto Rico (average age = 101. 5 years). Internal resilience factors associated with the aging process were identifying, those were: emotional stability, optimism, behavioral factor and behavioral and emotional skills component. These factors are consistent with the revised literature on positive emotions and adaptive ageing. On the other hand, no statistically significant difference was identified (p <. 05) for the internal factors of resilience on the basis of gender, a finding agreed with the revised literature. The multiple tests administered showed adequate internal consistency (EFIR: (=. 726); SCL-90-R: (=. 941). The Symptoms Check list 90-R (SCL-90-R) was valid with a Cronbach's alpha of. 941. We identified internal resilience factors that could be linked with successfully aging: those factors are encouraging the elderly population. In addition used tests showed adequate internal consistency. Limitations in relation to the size of the sample and the distribution of gender were identified, thus we suggest further research with larger samples.

International VLBI Service for Geodesy and Astrometry 2005 Annual Report

NASA Technical Reports Server (NTRS)

Behrend, Dirk (Editor); Baver, Karen D. (Editor)

2006-01-01

This volume of reports is the 2005 Annual Report of the International VLBI Service for Geodesy and Astrometry (IVS). The individual reports were contributed by VLBI groups in the international geodetic and astrometric community who constitute the components of IVS. The 2005 Annual Report documents the work of these IVS components over the period January 1, 2005 through December 31, 2005. The reports document changes, activities, and progress of the IVS. The entire contents of this Annual Report also appear on the IVS Web site at http://ivscc.gsfc.nasa.gov/publications/ar2005.

International VLBI Service for Geodesy and Astrometry

NASA Technical Reports Server (NTRS)

Vandenberg, Nancy R. (Editor); Baver, Karen D. (Editor)

2001-01-01

This volume of reports is the 2000 Annual Report of the International Very Long Base Interferometry (VLBI) Service for Geodesy and Astrometry (IVS). The individual reports were contributed by VLBI groups in the international geodetic and astrometric community who constitute the components of IVS. The 2000 Annual Report documents the work of these IVS components over the period March 1, 1999, through December 31, 2000. The reports document changes, activities, and progress of the IVS. The entire contents of this Annual Report also appear on the IVS web site at http://ivscc.gsfc.nasa.gov/publications/ar2000.

International VLBI Service for Geodesy and Astrometry 2007 Annual Report

NASA Technical Reports Server (NTRS)

Behrend, D. (Editor); Baver, K. D. (Editor)

2008-01-01

This volume of reports is the 2007 Annual Report of the International VLBI Service for Geodesy and Astrometry (IVS). The individual reports were contributed by VLBI groups in the international geodetic and astrometric community who constitute the components of IVS. The 2007 Annual Report documents the work of these IVS components over the period January 1, 2007 through December 31, 2007. The reports document changes, activities, and progress of the IVS. The entire contents of this Annual Report also appear on the IVS Web site at http://ivscc.gsfc.nasa.gov/publications/ar2007.

International VLBI Service for Geodesy and Astrometry 2008 Annual Report

NASA Technical Reports Server (NTRS)

Behrend, Dirk; Baver, Karen D.

2009-01-01

This volume of reports is the 2008 Annual Report of the International VLBI Service for Geodesy and Astrometry (IVS). The individual reports were contributed by VLBI groups in the international geodetic and astrometric community who constitute the components of IVS. The 2008 Annual Report documents the work of these IVS components over the period January 1, 2008 through December 31, 2008. The reports document changes, activities, and progress of the IVS. The entire contents of this Annual Report also appear on the IVS Web site at http://ivscc.gsfc.nasa.gov/publications/ar2008.

International VLBI Service for Geodesy and Astrometry 2011 Annual Report

NASA Technical Reports Server (NTRS)

Baver, Karen D. (Editor); Behrend, Dirk

2012-01-01

This volume of reports is the 2011 Annual Report of the International VLBI Service for Geodesy and Astrometry (IVS). The individual reports were contributed by VLBI groups in the international geodetic and astrometric community who constitute the components of IVS. The 2011 Annual Report documents the work of these IVS components over the period January 1, 2011 through December 31, 2011. The reports document changes, activities, and progress of the IVS. The entire contents of this Annual Report also appear on the IVS Web site at http://ivscc.gsfc.nasa.gov/publications/ar2011.

Brain mechanisms associated with internally directed attention and self-generated thought.

PubMed

Benedek, Mathias; Jauk, Emanuel; Beaty, Roger E; Fink, Andreas; Koschutnig, Karl; Neubauer, Aljoscha C

2016-03-10

Internal cognition like imagination and prospection require sustained internally directed attention and involve self-generated thought. This fMRI study aimed to disentangle the brain mechanisms associated with attention-specific and task-specific processes during internally directed cognition. The direction of attention was manipulated by either keeping a relevant stimulus visible throughout the task, or by masking it, so that the task had to be performed "in the mind's eye". The level of self-directed thought was additionally varied between a convergent and a divergent thinking task. Internally directed attention was associated with increased activation in the right anterior inferior parietal lobe (aIPL), bilateral lingual gyrus and the cuneus, as well as with extended deactivations of superior parietal and occipital regions representing parts of the dorsal attention network. The right aIPL further showed increased connectivity with occipital regions suggesting an active top-down mechanism for shielding ongoing internal processes from potentially distracting sensory stimulation in terms of perceptual decoupling. Activation of the default network was not related to internally directed attention per se, but rather to a higher level of self-generated thought. The findings hence shed further light on the roles of inferior and superior parietal cortex for internally directed cognition.

Growth in Externalizing and Internalizing Problems in Childhood: A Prospective Study of Psychopathology across Three Generations

ERIC Educational Resources Information Center

Capaldi, Deborah M.; Pears, Katherine C.; Kerr, David C. R.; Owen, Lee D.; Kim, Hyoun K.

2012-01-01

Three generations of participants were assessed over approximately 27 years, and intergenerational prediction models of growth in the third generation's (G3) externalizing and internalizing problems across ages 3-9 years were examined. The sample included 103 fathers and mothers (G2), at least 1 parent (G1) for all of the G2 fathers (99 mothers,…

Status of the Flooding Fragility Testing Development

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pope, C. L.; Savage, B.; Bhandari, B.

2016-06-01

This report provides an update on research addressing nuclear power plant component reliability under flooding conditions. The research includes use of the Component Flooding Evaluation Laboratory (CFEL) where individual components and component subassemblies will be tested to failure under various flooding conditions. The resulting component reliability data can then be incorporated with risk simulation strategies to provide a more thorough representation of overall plant risk. The CFEL development strategy consists of four interleaved phases. Phase 1 addresses design and application of CFEL with water rise and water spray capabilities allowing testing of passive and active components including fully electrified components.more » Phase 2 addresses research into wave generation techniques followed by the design and addition of the wave generation capability to CFEL. Phase 3 addresses methodology development activities including small scale component testing, development of full scale component testing protocol, and simulation techniques including Smoothed Particle Hydrodynamic (SPH) based computer codes. Phase 4 involves full scale component testing including work on full scale component testing in a surrogate CFEL testing apparatus.« less

75 FR 20861 - Certain Digital Set-Top Boxes and Components Thereof; Notice of Investigation

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-21

... INTERNATIONAL TRADE COMMISSION [Inv. No. 337-TA-712] Certain Digital Set-Top Boxes and Components... the United States after importation of certain digital set-top boxes and components thereof that... after importation of certain digital set- top boxes and components thereof that infringe one or more of...

Components of a Course on National Security Policy.

ERIC Educational Resources Information Center

Quester, George H.

1987-01-01

Describes the components of a course on the formation of national security policy. Includes information on the amount of emphasis and instructional approach to take with each component of the course. Components include the nature of strategy, the role of war in international politics, disarmament and arms control, nuclear weapons and nuclear war,…

Towards an integrated AlGaAs waveguide platform for phase and polarisation shaping

NASA Astrophysics Data System (ADS)

Maltese, G.; Halioua, Y.; Lemaître, A.; Gomez-Carbonell, C.; Karimi, E.; Banzer, P.; Ducci, S.

2018-05-01

We propose, design and fabricate an on-chip AlGaAs waveguide capable of generating a controlled phase delay of π/2 between the guided transverse electric and magnetic modes. These modes possess significantly strong longitudinal field components as a direct consequence of their strong lateral confinement in the waveguide. We demonstrate that the effect of the device on a linearly polarised input beam is the generation of a field, which is circularly polarised in its transverse components and carries a phase vortex in its longitudinal component. We believe that the discussed integrated platform enables the generation of light beams with tailored phase and polarisation distributions.

U.S. National Defense Acquisition and Budgetary Policy in an International Perspective

DTIC Science & Technology

2011-12-03

from the scale and learning economies generated by the world’s largest internal defense market. When combined with the effects of high defense...scale economies , explain why high domestic spending sustains international competitiveness. Since the 1950s, research has demonstrated that the... economies of scale and avoid the necessity of closing production lines between national orders, which both generates unemployment and results in the loss

Introducing causality violation for improved DPOAE component unmixing

NASA Astrophysics Data System (ADS)

Moleti, Arturo; Sisto, Renata; Shera, Christopher A.

2018-05-01

The DPOAE response consists of the linear superposition of two components, a nonlinear distortion component generated in the overlap region, and a reflection component generated by roughness in the DP resonant region. Due to approximate scaling symmetry, the DPOAE distortion component has approximately constant phase. As the reflection component may be considered as a SFOAE generated by the forward DP traveling wave, it has rapidly rotating phase, relative to that of its source, which is also equal to the phase of the DPOAE distortion component. This different phase behavior permits effective separation of the DPOAE components (unmixing), using time-domain or time-frequency domain filtering. Departures from scaling symmetry imply fluctuations around zero delay of the distortion component, which may seriously jeopardize the accuracy of these filtering techniques. The differential phase-gradient delay of the reflection component obeys causality requirements, i.e., the delay is positive only, and the fine-structure oscillations of amplitude and phase are correlated to each other, as happens for TEOAEs and SFOAEs relative to their stimulus phase. Performing the inverse Fourier (or wavelet) transform of a modified DPOAE complex spectrum, in which a constant phase function is substituted for the measured one, the time (or time-frequency) distribution shows a peak at (exactly) zero delay and long-latency specular symmetric components, with a modified (positive and negative) delay, which is that relative to that of the distortion component in the original response. Component separation, applied to this symmetrized distribution, becomes insensitive to systematic errors associated with violation of the scaling symmetry in specific frequency ranges.

77 FR 50716 - Certain Food Waste Disposers and Components and Packaging Thereof; Notice of Commission...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-22

... INTERNATIONAL TRADE COMMISSION [Investigation No. 337-TA-838] Certain Food Waste Disposers and.... International Trade Commission. ACTION: Notice. SUMMARY: Notice is hereby given that the U.S. International.... International Trade Commission, 500 E Street SW., Washington, DC 20436, telephone (202) 205-2737. Copies of non...

College Influence on Student Intentions toward International Competence. ASHE Annual Meeting Paper.

ERIC Educational Resources Information Center

English, Susan Lewis

This study attempted to test the concept of international competence as a construct and to estimate the extent to which college experience predicts variance on student intentions toward international competence. Relying on Lambert's model of global competence, the study tested five components of international competence for validity and…

A Feasibility Study on Generation of Acoustic Waves Utilizing Evanescent Light

NASA Astrophysics Data System (ADS)

Matsuya, I.; Matozaki, K.; Kosugi, A.; Ihara, I.

2014-06-01

A new approach of generating acoustic waves utilizing evanescent light is presented. The evanescent light is a non-propagating electromagnetic wave that exhibits exponential decay with distance from the surface at which the total internal reflection of light is formed. In this research, the evanescent light during total internal reflection at prism surface is utilized for generating acoustic waves in aluminium and the feasibility for ultrasonic measurements is discussed. Pulsed Nd:YAG laser with 0.36 J/cm2 power density is used and the incident angle during the total internal reflection is arranged to be 69.0° for generating the evanescent light. It has been demonstrated that the amplitude of the acoustic waves by means of evanescent light is about 1/14 as large as the one generated by the conventional pulsed laser. This reveals the possibility of using a laser ultrasonic technique with near-field optics.

Origins of cellular geometry

PubMed Central

2011-01-01

Cells are highly complex and orderly machines, with defined shapes and a startling variety of internal organizations. Complex geometry is a feature of both free-living unicellular organisms and cells inside multicellular animals. Where does the geometry of a cell come from? Many of the same questions that arise in developmental biology can also be asked of cells, but in most cases we do not know the answers. How much of cellular organization is dictated by global cell polarity cues as opposed to local interactions between cellular components? Does cellular structure persist across cell generations? What is the relationship between cell geometry and tissue organization? What ensures that intracellular structures are scaled to the overall size of the cell? Cell biology is only now beginning to come to grips with these questions. PMID:21880160

Mexican American female adolescents' perceptions of relationships and dating violence.

PubMed

Haglund, Kristin; Belknap, Ruth Ann; Garcia, Juanita Terrie

2012-09-01

This study fills a gap regarding the perspectives of Mexican American female adolescents on dating relationships and dating violence (DV). This was a qualitative descriptive study. Focus groups included 20 Mexican American young women, primarily first and second generation, mean age 14.5 years (SD= 2.5). Data were analyzed with categorical analysis. Participants described key components of DV and identified cultural aspects that may serve to promote healthy dating relationships. Family-based interventions to promote exploration of gender roles and parent-child communication may foster biculturalism as well as promote healthy dating relationships and prevent violence within this cultural group. In the United States, 10% to 40% of teens experience DV. Hispanic females experience more physical DV than their White peers. © 2012 Sigma Theta Tau International.

STS-106 Crew Activity Report/Flight Day 8 Highlights

NASA Technical Reports Server (NTRS)

2000-01-01

On this eighth day of the STS-106 Atlantis mission, the flight crew, Commander Terrence W. Wilcutt, Pilot Scott T. Altman, and Mission Specialists Daniel C. Burbank, Edward T. Lu, Richard A. Mastracchio, Yuri Ivanovich Malenchenko, and Boris V. Morukov move into the second half of preparing the International Space Station (ISS) for its first resident crew. Lu and Malenchenko are seen installing the power converters in the Zvezda module and components of the primary oxygen generation system. Mastracchio and Wilcutt moves supplies and logistics from the payload of Atlantis to the ISS. Wilcutt and Altman participate in several interviews and the crew wishes the Olympiads in Sydney good luck in their endeavors. Scenes also include external views of the ISS and images of Earth, including Sydney, Australia.

Large improvement of phosphorus incorporation efficiency in n-type chemical vapor deposition of diamond

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ohtani, Ryota; Yamamoto, Takashi; Janssens, Stoffel D.

2014-12-08

Microwave plasma enhanced chemical vapor deposition is a promising way to generate n-type, e.g., phosphorus-doped, diamond layers for the fabrication of electronic components, which can operate at extreme conditions. However, a deeper understanding of the doping process is lacking and low phosphorus incorporation efficiencies are generally observed. In this work, it is shown that systematically changing the internal design of a non-commercial chemical vapor deposition chamber, used to grow diamond layers, leads to a large increase of the phosphorus doping efficiency in diamond, produced in this device, without compromising its electronic properties. Compared to the initial reactor design, the dopingmore » efficiency is about 100 times higher, reaching 10%, and for a very broad doping range, the doping efficiency remains highly constant. It is hypothesized that redesigning the deposition chamber generates a higher flow of active phosphorus species towards the substrate, thereby increasing phosphorus incorporation in diamond and reducing deposition of phosphorus species at reactor walls, which additionally reduces undesirable memory effects.« less

The evolution of global disaster risk assessments: from hazard to global change

NASA Astrophysics Data System (ADS)

Peduzzi, Pascal

2013-04-01

The perception of disaster risk as a dynamic process interlinked with global change is a fairly recent concept. It gradually emerged as an evolution from new scientific theories, currents of thinking and lessons learned from large disasters since the 1970s. The interest was further heighten, in the mid-1980s, by the Chernobyl nuclear accident and the discovery of the ozone layer hole, both bringing awareness that dangerous hazards can generate global impacts. The creation of the UN International Decade for Natural Disaster Reduction (IDNDR) and the publication of the first IPCC report in 1990 reinforced the interest for global risk assessment. First global risk models including hazard, exposure and vulnerability components were available since mid-2000s. Since then increased computation power and more refined datasets resolution, led to more numerous and sophisticated global risk models. This article presents a recent history of global disaster risk models, the current status of researches for the Global Assessment Report on Disaster Risk Reduction (GAR 2013) and future challenges and limitations for the development of next generation global disaster risk models.

Imaging intracellular protein dynamics by spinning disk confocal microscopy

PubMed Central

Stehbens, Samantha; Pemble, Hayley; Murrow, Lindsay; Wittmann, Torsten

2012-01-01

The palette of fluorescent proteins has grown exponentially over the last decade, and as a result live imaging of cells expressing fluorescently tagged proteins is becoming more and more main stream. Spinning disk confocal microscopy (SDC) is a high speed optical sectioning technique, and a method of choice to observe and analyze intracellular fluorescent protein dynamics at high spatial and temporal resolution. In an SDC system, a rapidly rotating pinhole disk generates thousands of points of light that scan the specimen simultaneously, which allows direct capture of the confocal image with low noise scientific grade cooled charged-coupled device (CCD) cameras, and can achieve frame rates of up 1000 frames per second. In this chapter we describe important components of a state-of-the-art spinning disk system optimized for live cell microscopy, and provide a rationale for specific design choices. We also give guidelines how other imaging techniques such as total internal reflection (TIRF) microscopy or spatially controlled photoactivation can be coupled with SDC imaging, and provide a short protocol on how to generate cell lines stably expressing fluorescently tagged proteins by lentivirus-mediated transduction. PMID:22264541

Computational Support of 9x7 Wind Tunnel Test of Sonic Boom Models with Plumes

NASA Technical Reports Server (NTRS)

Jensen, James C.; Denison, Marie; Durston, Don; Cliff, Susan E.

2017-01-01

NASA and its industry partners are performing studies of supersonic aircraft concepts with low sonic boom pressure signatures. The interaction of the nozzle jet flow with the aircrafts' aft components is typically where the greatest uncertainly in the pressure signature is observed with high-fidelity numerical simulations. An extensive wind tunnel test was conducted in February 2016 in the NASA Ames 9- by 7- Foot Supersonic Wind Tunnel to help address the nozzle jet effects on sonic boom. Five test models with a variety of shock generators of differing waveforms and strengths were tested with a convergent-divergent nozzle for a wide range of nozzle pressure ratios. The LAVA unstructured flow solver was used to generate first CFD comparisons with the new experimental database using best practice meshing and analysis techniques for sonic boom vehicle design for all five different configurations. LAVA was also used to redesign the internal flow path of the nozzle and to better understand the flow field in the test section, both of which significantly improved the quality of the test data.

4-alkyl-L-(Dehydro)proline biosynthesis in actinobacteria involves N-terminal nucleophile-hydrolase activity of γ-glutamyltranspeptidase homolog for C-C bond cleavage

NASA Astrophysics Data System (ADS)

Zhong, Guannan; Zhao, Qunfei; Zhang, Qinglin; Liu, Wen

2017-07-01

γ-Glutamyltranspeptidases (γ-GTs), ubiquitous in glutathione metabolism for γ-glutamyl transfer/hydrolysis, are N-terminal nucleophile (Ntn)-hydrolase fold proteins that share an autoproteolytic process for self-activation. γ-GT homologues are widely present in Gram-positive actinobacteria where their Ntn-hydrolase activities, however, are not involved in glutathione metabolism. Herein, we demonstrate that the formation of 4-Alkyl-L-(dehydro)proline (ALDP) residues, the non-proteinogenic α-amino acids that serve as vital components of many bioactive metabolites found in actinobacteria, involves unprecedented Ntn-hydrolase activity of γ-GT homologue for C-C bond cleavage. The related enzymes share a key Thr residue, which acts as an internal nucleophile for protein hydrolysis and then as a newly released N-terminal nucleophile for carboxylate side-chain processing likely through the generation of an oxalyl-Thr enzyme intermediate. These findings provide mechanistic insights into the biosynthesis of various ALDP residues/associated natural products, highlight the versatile functions of Ntn-hydrolase fold proteins, and particularly generate interest in thus far less-appreciated γ-GT homologues in actinobacteria.

NASA powered lift facility internally generated noise and its transmission to the acoustic far field

NASA Technical Reports Server (NTRS)

Huff, Ronald G.

1988-01-01

Noise tests of NASA Lewis Research Center's Powered Lift Facility (PLF) were performed to determine the frequency content of the internally generated noise that reaches the far field. The sources of the internally generated noise are the burner, elbows, valves, and flow turbulence. Tests over a range of nozzle pressure ratios from 1.2 to 3.5 using coherence analysis revealed that low frequency noise below 1200 Hz is transmitted through the nozzle. Broad banded peaks at 240 and 640 Hz were found in the transmitted noise. Aeroacoustic excitation effects are possible in this frequency range. The internal noise creates a noise floor that limits the amount of jet noise suppression that can be measured on the PLF and similar facilities.

Influence of glenoid component design and humeral component retroversion on internal and external rotation in reverse shoulder arthroplasty: a cadaver study.

PubMed

Berhouet, J; Garaud, P; Favard, L

2013-12-01

A common disadvantage of reverse shoulder arthroplasty is limitation of the range of arm rotation. Several changes to the prosthesis design and implantation technique have been suggested to improve rotation range of motion (ROM). Glenoid component design and degree of humeral component retroversion influence rotation ROM after reverse shoulder arthroplasty. The Aequalis Reversed™ shoulder prosthesis (Tornier Inc., Edina, MN, USA) was implanted into 40 cadaver shoulders. Eight glenoid component combinations were tested, five with the 36-mm sphere (centred seating, eccentric seating, inferior tilt, centred with a 5-mm thick lateralised spacer, and centred with a 7-mm thick lateralised spacer) and three with the 42-mm sphere (centred with no spacer or with a 7-mm or 10-mm spacer). Humeral component position was evaluated with 0°, 10°, 20°, 30°, and 40° of retroversion. External and internal rotation ROMs to posterior and anterior impingement on the scapular neck were measured with the arm in 20° of abduction. The large glenosphere (42 mm) was associated with significantly (P<0.05) greater rotation ROMs, particularly when combined with a lateralised spacer (46° internal and 66° external rotation). Rotation ROMs were smallest with the 36-mm sphere. Greater humeral component retroversion was associated with a decrease in internal rotation and a significant increase (P<0.05) in external rotation. The best balance between rotation ROMs was obtained with the native retroversion, which was estimated at 17.5° on average in this study. Our anatomic study in a large number of cadavers involved a detailed and reproducible experimental protocol. However, we did not evaluate the variability in scapular anatomy. Earlier studies of the influence of technical parameters did not take humeral component retroversion into account. In addition, no previous studies assessed rotation ROMs. Rotation ROM should be improved by the use of a large-diameter glenosphere with a spacer to lateralise the centre of rotation of the gleno-humeral joint, as well as by positioning the humeral component at the patient's native retroversion value. Copyright © 2013 Elsevier Masson SAS. All rights reserved.

Different dynamin blockers interfere with distinct phases of synaptic endocytosis during stimulation in motoneurones

PubMed Central

Linares-Clemente, Pedro; Rozas, José L; Mircheski, Josif; García-Junco-Clemente, Pablo; Martínez-López, José A; Nieto-González, José L; Vázquez, M Eugenio; Pintado, C Oscar; Fernández-Chacón, Rafael

2015-01-01

Key points Neurotransmitter release requires a tight coupling between synaptic vesicle exocytosis and endocytosis with dynamin being a key protein in that process. We used imaging techniques to examine the time course of endocytosis at mouse motor nerve terminals expressing synaptopHluorin, a genetically encoded reporter of the synaptic vesicle cycle. We separated two sequential phases of endocytosis taking place during the stimulation train: early and late endocytosis. Freshly released synaptic vesicle proteins are preferentially retrieved during the early phase, which is very sensitive to dynasore, an inhibitor of dynamin GTPase activity. Synaptic vesicle proteins pre-existing at the plasma membrane before the stimulation are preferentially retrieved during the late phase, which is very sensitive to myristyl trimethyl ammonium bromide (MitMAB), an inhibitor of the dynamin–phospholipid interaction. Abstract Synaptic endocytosis is essential at nerve terminals to maintain neurotransmitter release by exocytosis. Here, at the neuromuscular junction of synaptopHluorin (spH) transgenic mice, we have used imaging to study exo- and endocytosis occurring simultaneously during nerve stimulation. We observed two endocytosis components, which occur sequentially during stimulation. The early component of endocytosis apparently internalizes spH molecules freshly exocytosed. This component was sensitive to dynasore, a blocker of dynamin 1 GTPase activity. In contrast, this early component was resistant to myristyl trimethyl ammonium bromide (MiTMAB), a competitive agent that blocks dynamin binding to phospholipid membranes. The late component of endocytosis is likely to internalize spH molecules that pre-exist at the plasma membrane before stimulation starts. This component was blocked by MiTMAB, perhaps by impairing the binding of dynamin or other key endocytic proteins to phospholipid membranes. Our study suggests the co-existence of two sequential synaptic endocytosis steps taking place during stimulation that are susceptible to pharmacological dissection: an initial step, preferentially sensitive to dynasore, that internalizes vesicular components immediately after they are released, and a MiTMAB-sensitive step that internalizes vesicular components pre-existing at the plasma membrane surface. In addition, we report that post-stimulus endocytosis also has several components with different sensitivities to dynasore and MiTMAB. PMID:25981717

Different dynamin blockers interfere with distinct phases of synaptic endocytosis during stimulation in motoneurones.

PubMed

Linares-Clemente, Pedro; Rozas, José L; Mircheski, Josif; García-Junco-Clemente, Pablo; Martínez-López, José A; Nieto-González, José L; Vázquez, M Eugenio; Pintado, C Oscar; Fernández-Chacón, Rafael

2015-07-01

Neurotransmitter release requires a tight coupling between synaptic vesicle exocytosis and endocytosis with dynamin being a key protein in that process. We used imaging techniques to examine the time course of endocytosis at mouse motor nerve terminals expressing synaptopHluorin, a genetically encoded reporter of the synaptic vesicle cycle. We separated two sequential phases of endocytosis taking place during the stimulation train: early and late endocytosis. Freshly released synaptic vesicle proteins are preferentially retrieved during the early phase, which is very sensitive to dynasore, an inhibitor of dynamin GTPase activity. Synaptic vesicle proteins pre-existing at the plasma membrane before the stimulation are preferentially retrieved during the late phase, which is very sensitive to myristyl trimethyl ammonium bromide (MitMAB), an inhibitor of the dynamin-phospholipid interaction. Synaptic endocytosis is essential at nerve terminals to maintain neurotransmitter release by exocytosis. Here, at the neuromuscular junction of synaptopHluorin (spH) transgenic mice, we have used imaging to study exo- and endocytosis occurring simultaneously during nerve stimulation. We observed two endocytosis components, which occur sequentially during stimulation. The early component of endocytosis apparently internalizes spH molecules freshly exocytosed. This component was sensitive to dynasore, a blocker of dynamin 1 GTPase activity. In contrast, this early component was resistant to myristyl trimethyl ammonium bromide (MiTMAB), a competitive agent that blocks dynamin binding to phospholipid membranes. The late component of endocytosis is likely to internalize spH molecules that pre-exist at the plasma membrane before stimulation starts. This component was blocked by MiTMAB, perhaps by impairing the binding of dynamin or other key endocytic proteins to phospholipid membranes. Our study suggests the co-existence of two sequential synaptic endocytosis steps taking place during stimulation that are susceptible to pharmacological dissection: an initial step, preferentially sensitive to dynasore, that internalizes vesicular components immediately after they are released, and a MiTMAB-sensitive step that internalizes vesicular components pre-existing at the plasma membrane surface. In addition, we report that post-stimulus endocytosis also has several components with different sensitivities to dynasore and MiTMAB. © 2015 The Authors. The Journal of Physiology © 2015 The Physiological Society.

77 FR 32996 - Certain Handheld Electronic Computing Devices, Related Software, and Components Thereof...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-04

... INTERNATIONAL TRADE COMMISSION [Investigation No. 337-TA-769] Certain Handheld Electronic Computing Devices, Related Software, and Components Thereof; Termination of the Investigation Based on... electronic computing devices, related software, and components thereof by reason of infringement of certain...