Sample records for interplanetary network ipn
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3rd Interplanetary Network Gamma-Ray Burst Website
NASA Astrophysics Data System (ADS)
Hurley, Kevin
1998-05-01
We announce the opening of the 3rd Interplanetary Network web site at http://ssl.berkeley.edu/ipn3/index.html This site presently has four parts: 1. A bibliography of over 3000 publications on gamma-ray bursts, 2. IPN data on all bursts triangulated up to February 1998, 3. A master list showing which spacecraft observed which bursts, 4. Preliminary IPN data on the latest bursts observed.
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NASA Technical Reports Server (NTRS)
Hurley, K.; Briggs, M.; Connaughton, V.; Meegan, C.; von Kienlin, A.; Rau, A.; Zhang, X.; Golenetskii, S.; Aptekar, R.; Mazets, E.;
2012-01-01
In the first two years of operation of the Fermi GBM, the 9-spacecraft Interplanetary Network (IPN) detected 158 GBM bursts with one or two distant spacecraft, and triangulated them to annuli or error boxes. Combining the IPN and GBM localizations leads to error boxes which are up to 4 orders of magnitude smaller than those of the GBM alone. These localizations comprise the IPN supplement to the GBM catalog, and they support a wide range of scientific investigations.
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The Interplanetary Internet: A Communications Infrastructure for Mars Exploration
NASA Astrophysics Data System (ADS)
Burleigh, S.; Cerf, V.; Durst, R.; Fall, K.; Hooke, A.; Scott, K.; Weiss, H.
2002-01-01
A successful program of Mars Exploration will depend heavily on a robust and dependable space communications infrastructure that is well integrated with the terrestrial Internet. In the same way that the underpinnings of the Internet are the standardized "TCP/IP" suite of protocols, an "Interplanetary Internet" will need a similar set of capabilities that can support reliable communications across vast distances and highly stressed communications environments. For the past twenty years, the Consultative Committee for Space Data Systems (CCSDS) has been developing standardized long- haul space link communications techniques that are now in use by over two hundred missions within the international space community. New CCSDS developments, shortly to be infused into Mars missions, include a proximity link standard and a store-and- forward file transfer protocol. As part of its `Next Generation Internet' initiative, the U.S. Defense Advanced Projects Agency (DARPA) recently supported an architectural study of a future "InterPlaNetary Internet" (IPN). The IPN architecture assumes that in short-delay environments - such as on and around Mars - standard Internet technologies will be adapted to the locally harsh environment and deployed within surface vehicles and orbiting relays. A long-haul interplanetary backbone network that includes Deep Space Network (DSN) gateways into the terrestrial Internet will interconnect these distributed internets that are scattered across the Solar System. Just as TCP/IP unites the Earth's "network of networks" to become the Internet, a new suite of protocols known as "Bundling" will enable the IPN to become a "network of internets" to support true interplanetary dialog. An InterPlaNetary Internet Research Group has been established within the Internet community to coordinate this research and NASA has begun to support the further development of the IPN architecture and the Bundling protocols. A strategy is being developed whereby the current set of standard CCSDS data communications protocols can be incrementally evolved so that true InterPlaNetary Internet operations are feasible by the end of the decade. The strategy - which is already in progress via the deployment of Mars relay links - needs individual missions to each contribute increments of capability so that a standard communications infrastructure can rapidly accrete. This paper will describe the IPN architectural concepts, discuss the current set of standard data communications capabilities that exist to support Mars exploration and review the proposed new developments. We will also postulate that the concept is scalable and can grow to support future scenarios where human intelligence is widely distributed across the Solar System and day-to-day communications dialog among planets is routine. 1 2 3 4 5
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The InterPlanetary Network Supplement to the Second Fermi GBM Catalog of Cosmic Gamma-Ray Bursts
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hurley, K.; Aptekar, R. L.; Golenetskii, S. V.
InterPlanetary Network (IPN) data are presented for the gamma-ray bursts in the second Fermi Gamma-Ray Burst Monitor (GBM) catalog. Of the 462 bursts in that catalog between 2010 July 12 and 2012 July 11, 428, or 93%, were observed by at least 1 other instrument in the 9-spacecraft IPN. Of the 428, the localizations of 165 could be improved by triangulation. For these bursts, triangulation gives one or more annuli whose half-widths vary between about 2.′3° and 16°, depending on the peak flux, fluence, time history, arrival direction, and the distance between the spacecraft. We compare the IPN localizations withmore » the GBM 1 σ , 2 σ , and 3 σ error contours and find good agreement between them. The IPN 3 σ error boxes have areas between about 8 square arcminutes and 380 square degrees, and are an average of 2500 times smaller than the corresponding GBM 3 σ localizations. We identify four bursts in the IPN/GBM sample whose origins were given as “uncertain,” but may in fact be cosmic. This leads to an estimate of over 99% completeness for the GBM catalog.« less
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The Interplanetary Network Response to LIGO GW150914
NASA Technical Reports Server (NTRS)
Hurley, K.; Svinkin, D. S.; Aptekar, R.L.; Golenetskii, S. V.; Frederiks, D. D.; Boynton, W.; Mitrofanov, I. G.; Golovin, D. V.; Kozyrev, A. S.; Litvak, M. L.;
2016-01-01
We have performed a blind search for a gamma-ray transient of arbitrary duration and energy spectrum around the time of the LIGO gravitational-wave event GW150914 with the six-spacecraft interplanetary network (IPN). Four gamma-ray bursts were detected between 30 hr prior to the event and 6.1 hr after it, but none could convincingly be associated with GW150914. No other transients were detected down to limiting 15-150 keV fluences of roughly 5 x 10(exp -8) -5 x 10(exp -7) erg cm(exp -2). We discuss the search strategies and temporal coverage of the IPN on the day of the event and compare the spatial coverage to the region where GW150914 originated. We also report the negative result of a targeted search for the Fermi-GBM event reported in conjunction with GW150914.
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GRB 080407: An Ultra-long Burst Discovered by the IPN
NASA Technical Reports Server (NTRS)
Cummings, J; Barthelmy, S.; Gehrels, N.; Krimm, H.; Palmer, D.; Palshin, V.; Hurley, K.; Goldsten, J.; Mitrofanov, I. G.; Boynton, W.;
2012-01-01
We present observations of the extremely long GRB 080704 obtained with the instruments of the Interplanetary Network (IPN). The observations reveal two distinct emission episodes, separated by a approx.1500 s long period of quiescence. The total burst duration is about 2100 s. We compare the temporal and spectral characteristics of this burst with those obtained for other ultra-long GRBs and discuss these characteristics in the context of different models.
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The Interplanetary Network II: 11 Months of Rapid, Precise GRB Localizations
NASA Astrophysics Data System (ADS)
Hurley, K.; Cline, T.; Mazets, E.; Golenetskii, S.; Trombka, J.; Feroci, M.; Kippen, R. M.; Barthelmy, S.; Frontera, F.; Guidorzi, C.; Montanari, E.
2000-10-01
Since December 1999 the 3rd Interplanetary Network has been producing small ( 10') error boxes at a rate of about one per week, and circulating them rapidly ( 24 h) via the GCN. As of June 2000, 24 such error boxes have been obtained; 18 of them have been searched in the radio and optical ranges for counterparts, resulting in four definite counterpart detections and three redshift determinations. We will review these results and explain the some of the lesser known IPN operations. In particular, we maintain an "early warning" list of potential observers with pagers and cell phones, and send messages to them to alert them to bursts for which error boxes will be obtained, allowing them to prepare for observations many hours before the complete spacecraft data are received and the GCN message is issued. As an interesting aside, now that the CGRO mission is terminated, the IPN consists entirely of non-NASA and/or non-astrophysics missions, specifically, Ulysses and Wind (Space Physics), NEAR (Planetary Physics), and BeppoSAX (ASI).
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Rossi X-Ray Timing Explorer All-Sky Monitor Localization of SGR 1627-41
NASA Astrophysics Data System (ADS)
Smith, Donald A.; Bradt, Hale V.; Levine, Alan M.
1999-07-01
The fourth unambiguously identified soft gamma repeater (SGR), SGR 1627-41, was discovered with the BATSE instrument on 1998 June 15. Interplanetary Network (IPN) measurements and BATSE data constrained the location of this new SGR to a 6° segment of a narrow (19") annulus. We present two bursts from this source observed by the All-Sky Monitor (ASM) on the Rossi X-Ray Timing Explorer. We use the ASM data to further constrain the source location to a 5' long segment of the BATSE/IPN error box. The ASM/IPN error box lies within 0.3 arcmin of the supernova remnant G337.0-0.1. The probability that a supernova remnant would fall so close to the error box purely by chance is ~5%.
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RXTE All-Sky Monitor Localization of SGR 1627-41
NASA Astrophysics Data System (ADS)
Smith, D. A.; Bradt, H. V.; Levine, A. M.
1999-09-01
The fourth unambiguously identified Soft Gamma Repeater (SGR), SGR 1627--41, was discovered with the BATSE instrument on 1998 June 15 (Kouveliotou et al. 1998). Interplanetary Network (IPN) measurements and BATSE data constrained the location of this new SGR to a 6(deg) segment of a narrow (19('') ) annulus (Hurley et al. 1999; Woods et al. 1998). We report on two bursts from this source observed by the All-Sky Monitor (ASM) on RXTE. We use the ASM data to further constrain the source location to a 5(') long segment of the BATSE/IPN error box. The ASM/IPN error box lies within 0.3(') of the supernova remnant (SNR) G337.0--0.1. The probability that a SNR would fall so close to the error box purely by chance is ~ 5%.
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Search for Gravitational Waves Associated with γ-ray Bursts Detected by the Interplanetary Network
NASA Astrophysics Data System (ADS)
Aasi, J.; Abbott, B. P.; Abbott, R.; Abbott, T.; Abernathy, M. R.; Acernese, F.; Ackley, K.; Adams, C.; Adams, T.; Addesso, P.; Adhikari, R. X.; Affeldt, C.; Agathos, M.; Aggarwal, N.; Aguiar, O. D.; Ajith, P.; Alemic, A.; Allen, B.; Allocca, A.; Amariutei, D.; Andersen, M.; Anderson, R. A.; Anderson, S. B.; Anderson, W. G.; Arai, K.; Araya, M. C.; Arceneaux, C.; Areeda, J. S.; Ast, S.; Aston, S. M.; Astone, P.; Aufmuth, P.; Augustus, H.; Aulbert, C.; Aylott, B. E.; Babak, S.; Baker, P. T.; Ballardin, G.; Ballmer, S. W.; Barayoga, J. C.; Barbet, M.; Barish, B. C.; Barker, D.; Barone, F.; Barr, B.; Barsotti, L.; Barsuglia, M.; Barton, M. A.; Bartos, I.; Bassiri, R.; Basti, A.; Batch, J. C.; Bauchrowitz, J.; Bauer, Th. S.; Baune, C.; Bavigadda, V.; Behnke, B.; Bejger, M.; Beker, M. G.; Belczynski, C.; Bell, A. S.; Bell, C.; Bergmann, G.; Bersanetti, D.; Bertolini, A.; Betzwieser, J.; Bilenko, I. A.; Billingsley, G.; Birch, J.; Biscans, S.; Bitossi, M.; Biwer, C.; Bizouard, M. A.; Black, E.; Blackburn, J. K.; Blackburn, L.; Blair, D.; Bloemen, S.; Bock, O.; Bodiya, T. P.; Boer, M.; Bogaert, G.; Bogan, C.; Bond, C.; Bondu, F.; Bonelli, L.; Bonnand, R.; Bork, R.; Born, M.; Boschi, V.; Bose, Sukanta; Bosi, L.; Bradaschia, C.; Brady, P. R.; Braginsky, V. B.; Branchesi, M.; Brau, J. E.; Briant, T.; Bridges, D. O.; Brillet, A.; Brinkmann, M.; Brisson, V.; Brooks, A. F.; Brown, D. A.; Brown, D. D.; Brückner, F.; Buchman, S.; Buikema, A.; Bulik, T.; Bulten, H. J.; Buonanno, A.; Burman, R.; Buskulic, D.; Buy, C.; Cadonati, L.; Cagnoli, G.; Calderón Bustillo, J.; Calloni, E.; Camp, J. B.; Campsie, P.; Cannon, K. C.; Canuel, B.; Cao, J.; Capano, C. D.; Carbognani, F.; Carbone, L.; Caride, S.; Castaldi, G.; Caudill, S.; Cavaglià, M.; Cavalier, F.; Cavalieri, R.; Celerier, C.; Cella, G.; Cepeda, C.; Cesarini, E.; Chakraborty, R.; Chalermsongsak, T.; Chamberlin, S. J.; Chao, S.; Charlton, P.; Chassande-Mottin, E.; Chen, X.; Chen, Y.; Chincarini, A.; Chiummo, A.; Cho, H. S.; Cho, M.; Chow, J. H.; Christensen, N.; Chu, Q.; Chua, S. S. Y.; Chung, S.; Ciani, G.; Clara, F.; Clark, D. E.; Clark, J. A.; Clayton, J. H.; Cleva, F.; Coccia, E.; Cohadon, P.-F.; Colla, A.; Collette, C.; Colombini, M.; Cominsky, L.; Constancio, M.; Conte, A.; Cook, D.; Corbitt, T. R.; Cornish, N.; Corsi, A.; Costa, C. A.; Coughlin, M. W.; Coulon, J.-P.; Countryman, S.; Couvares, P.; Coward, D. M.; Cowart, M. J.; Coyne, D. C.; Coyne, R.; Craig, K.; Creighton, J. D. E.; Croce, R. P.; Crowder, S. G.; Cumming, A.; Cunningham, L.; Cuoco, E.; Cutler, C.; Dahl, K.; Dal Canton, T.; Damjanic, M.; Danilishin, S. L.; D'Antonio, S.; Danzmann, K.; Dattilo, V.; Daveloza, H.; Davier, M.; Davies, G. S.; Daw, E. J.; Day, R.; Dayanga, T.; DeBra, D.; Debreczeni, G.; Degallaix, J.; Deléglise, S.; Del Pozzo, W.; Denker, T.; Dent, T.; Dereli, H.; Dergachev, V.; De Rosa, R.; DeRosa, R. T.; DeSalvo, R.; Dhurandhar, S.; Díaz, M.; Dickson, J.; Di Fiore, L.; Di Lieto, A.; Di Palma, I.; Di Virgilio, A.; Dolique, V.; Dominguez, E.; Donovan, F.; Dooley, K. L.; Doravari, S.; Douglas, R.; Downes, T. P.; Drago, M.; Drever, R. W. P.; Driggers, J. C.; Du, Z.; Ducrot, M.; Dwyer, S.; Eberle, T.; Edo, T.; Edwards, M.; Effler, A.; Eggenstein, H.-B.; Ehrens, P.; Eichholz, J.; Eikenberry, S. S.; Endrőczi, G.; Essick, R.; Etzel, T.; Evans, M.; Evans, T.; Factourovich, M.; Fafone, V.; Fairhurst, S.; Fan, X.; Fang, Q.; Farinon, S.; Farr, B.; Farr, W. M.; Favata, M.; Fazi, D.; Fehrmann, H.; Fejer, M. M.; Feldbaum, D.; Feroz, F.; Ferrante, I.; Ferreira, E. C.; Ferrini, F.; Fidecaro, F.; Finn, L. S.; Fiori, I.; Fisher, R. P.; Flaminio, R.; Fournier, J.-D.; Franco, S.; Frasca, S.; Frasconi, F.; Frede, M.; Frei, Z.; Freise, A.; Frey, R.; Fricke, T. T.; Fritschel, P.; Frolov, V. V.; Fulda, P.; Fyffe, M.; Gair, J. R.; Gammaitoni, L.; Gaonkar, S.; Garufi, F.; Gehrels, N.; Gemme, G.; Gendre, B.; Genin, E.; Gennai, A.; Ghosh, S.; Giaime, J. A.; Giardina, K. D.; Giazotto, A.; Gleason, J.; Goetz, E.; Goetz, R.; Gondan, L.; González, G.; Gordon, N.; Gorodetsky, M. L.; Gossan, S.; Goßler, S.; Gouaty, R.; Gräf, C.; Graff, P. B.; Granata, M.; Grant, A.; Gras, S.; Gray, C.; Greenhalgh, R. J. S.; Gretarsson, A. M.; Groot, P.; Grote, H.; Grover, K.; Grunewald, S.; Guidi, G. M.; Guido, C. J.; Gushwa, K.; Gustafson, E. K.; Gustafson, R.; Ha, J.; Hall, E. D.; Hamilton, W.; Hammer, D.; Hammond, G.; Hanke, M.; Hanks, J.; Hanna, C.; Hannam, M. D.; Hanson, J.; Harms, J.; Harry, G. M.; Harry, I. W.; Harstad, E. D.; Hart, M.; Hartman, M. T.; Haster, C.-J.; Haughian, K.; Heidmann, A.; Heintze, M.; Heitmann, H.; Hello, P.; Hemming, G.; Hendry, M.; Heng, I. S.; Heptonstall, A. W.; Heurs, M.; Hewitson, M.; Hild, S.; Hoak, D.; Hodge, K. A.; Hofman, D.; Holt, K.; Hopkins, P.; Horrom, T.; Hoske, D.; Hosken, D. J.; Hough, J.; Howell, E. J.; Hu, Y.; Huerta, E.; Hughey, B.; Husa, S.; Huttner, S. H.; Huynh, M.; Huynh-Dinh, T.; Idrisy, A.; Ingram, D. R.; Inta, R.; Islas, G.; Isogai, T.; Ivanov, A.; Iyer, B. R.; Izumi, K.; Jacobson, M.; Jang, H.; Jaranowski, P.; Ji, Y.; Jiménez-Forteza, F.; Johnson, W. W.; Jones, D. I.; Jones, R.; Jonker, R. J. G.; Ju, L.; Haris, K.; Kalmus, P.; Kalogera, V.; Kandhasamy, S.; Kang, G.; Kanner, J. B.; Karlen, J.; Kasprzack, M.; Katsavounidis, E.; Katzman, W.; Kaufer, H.; Kaufer, S.; Kaur, T.; Kawabe, K.; Kawazoe, F.; Kéfélian, F.; Keiser, G. M.; Keitel, D.; Kelley, D. B.; Kells, W.; Keppel, D. G.; Khalaidovski, A.; Khalili, F. Y.; Khazanov, E. A.; Kim, C.; Kim, K.; Kim, N. G.; Kim, N.; Kim, S.; Kim, Y.-M.; King, E. J.; King, P. J.; Kinzel, D. L.; Kissel, J. S.; Klimenko, S.; Kline, J.; Koehlenbeck, S.; Kokeyama, K.; Kondrashov, V.; Koranda, S.; Korth, W. Z.; Kowalska, I.; Kozak, D. B.; Kringel, V.; Krishnan, B.; Królak, A.; Kuehn, G.; Kumar, A.; Kumar, D. Nanda; Kumar, P.; Kumar, R.; Kuo, L.; Kutynia, A.; Lam, P. K.; Landry, M.; Lantz, B.; Larson, S.; Lasky, P. D.; Lazzarini, A.; Lazzaro, C.; Leaci, P.; Leavey, S.; Lebigot, E. O.; Lee, C. H.; Lee, H. K.; Lee, H. M.; Lee, J.; Lee, P. J.; Leonardi, M.; Leong, J. R.; Leonor, I.; Le Roux, A.; Leroy, N.; Letendre, N.; Levin, Y.; Levine, B.; Lewis, J.; Li, T. G. F.; Libbrecht, K.; Libson, A.; Lin, A. C.; Littenberg, T. B.; Lockerbie, N. A.; Lockett, V.; Lodhia, D.; Loew, K.; Logue, J.; Lombardi, A. L.; Lopez, E.; Lorenzini, M.; Loriette, V.; Lormand, M.; Losurdo, G.; Lough, J.; Lubinski, M. J.; Lück, H.; Lundgren, A. P.; Ma, Y.; Macdonald, E. P.; MacDonald, T.; Machenschalk, B.; MacInnis, M.; Macleod, D. M.; Magaña-Sandoval, F.; Magee, R.; Mageswaran, M.; Maglione, C.; Mailand, K.; Majorana, E.; Maksimovic, I.; Malvezzi, V.; Man, N.; Manca, G. M.; Mandel, I.; Mandic, V.; Mangano, V.; Mangini, N. M.; Mansell, G.; Mantovani, M.; Marchesoni, F.; Marion, F.; Márka, S.; Márka, Z.; Markosyan, A.; Maros, E.; Marque, J.; Martelli, F.; Martin, I. W.; Martin, R. M.; Martinelli, L.; Martynov, D.; Marx, J. N.; Mason, K.; Masserot, A.; Massinger, T. J.; Matichard, F.; Matone, L.; Mavalvala, N.; May, G.; Mazumder, N.; Mazzolo, G.; McCarthy, R.; McClelland, D. E.; McGuire, S. C.; McIntyre, G.; McIver, J.; McLin, K.; Meacher, D.; Meadors, G. D.; Mehmet, M.; Meidam, J.; Meinders, M.; Melatos, A.; Mendell, G.; Mercer, R. A.; Meshkov, S.; Messenger, C.; Meyer, M. S.; Meyers, P. M.; Mezzani, F.; Miao, H.; Michel, C.; Mikhailov, E. E.; Milano, L.; Miller, J.; Minenkov, Y.; Mingarelli, C. M. F.; Mishra, C.; Mitra, S.; Mitrofanov, V. P.; Mitselmakher, G.; Mittleman, R.; Moe, B.; Moggi, A.; Mohan, M.; Mohapatra, S. R. P.; Moraru, D.; Moreno, G.; Morgado, N.; Morriss, S. R.; Mossavi, K.; Mours, B.; Mow-Lowry, C. M.; Mueller, C. L.; Mueller, G.; Mukherjee, S.; Mullavey, A.; Munch, J.; Murphy, D.; Murray, P. G.; Mytidis, A.; Nagy, M. F.; Nardecchia, I.; Naticchioni, L.; Nayak, R. K.; Necula, V.; Nelemans, G.; Neri, I.; Neri, M.; Newton, G.; Nguyen, T.; Nielsen, A. B.; Nissanke, S.; Nitz, A. H.; Nocera, F.; Nolting, D.; Normandin, M. E. N.; Nuttall, L. K.; Ochsner, E.; O'Dell, J.; Oelker, E.; Oh, J. J.; Oh, S. H.; Ohme, F.; Omar, S.; Oppermann, P.; Oram, R.; O'Reilly, B.; Ortega, W.; O'Shaughnessy, R.; Osthelder, C.; Ottaway, D. J.; Ottens, R. S.; Overmier, H.; Owen, B. J.; Padilla, C.; Pai, A.; Palashov, O.; Palomba, C.; Pan, H.; Pan, Y.; Pankow, C.; Paoletti, F.; Papa, M. A.; Paris, H.; Pasqualetti, A.; Passaquieti, R.; Passuello, D.; Pedraza, M.; Pele, A.; Penn, S.; Perreca, A.; Phelps, M.; Pichot, M.; Pickenpack, M.; Piergiovanni, F.; Pierro, V.; Pinard, L.; Pinto, I. M.; Pitkin, M.; Poeld, J.; Poggiani, R.; Poteomkin, A.; Powell, J.; Prasad, J.; Predoi, V.; Premachandra, S.; Prestegard, T.; Price, L. R.; Prijatelj, M.; Privitera, S.; Prodi, G. A.; Prokhorov, L.; Puncken, O.; Punturo, M.; Puppo, P.; Pürrer, M.; Qin, J.; Quetschke, V.; Quintero, E.; Quitzow-James, R.; Raab, F. J.; Rabeling, D. S.; Rácz, I.; Radkins, H.; Raffai, P.; Raja, S.; Rajalakshmi, G.; Rakhmanov, M.; Ramet, C.; Ramirez, K.; Rapagnani, P.; Raymond, V.; Razzano, M.; Re, V.; Recchia, S.; Reed, C. M.; Regimbau, T.; Reid, S.; Reitze, D. H.; Reula, O.; Rhoades, E.; Ricci, F.; Riesen, R.; Riles, K.; Robertson, N. A.; Robinet, F.; Rocchi, A.; Roddy, S. B.; Rolland, L.; Rollins, J. G.; Romano, R.; Romanov, G.; Romie, J. H.; Rosińska, D.; Rowan, S.; Rüdiger, A.; Ruggi, P.; Ryan, K.; Salemi, F.; Sammut, L.; Sandberg, V.; Sanders, J. R.; Sankar, S.; Sannibale, V.; Santiago-Prieto, I.; Saracco, E.; Sassolas, B.; Sathyaprakash, B. S.; Saulson, P. R.; Savage, R.; Scheuer, J.; Schilling, R.; Schilman, M.; Schmidt, P.; Schnabel, R.; Schofield, R. M. S.; Schreiber, E.; Schuette, D.; Schutz, B. F.; Scott, J.; Scott, S. M.; Sellers, D.; Sengupta, A. S.; Sentenac, D.; Sequino, V.; Sergeev, A.; Shaddock, D. A.; Shah, S.; Shahriar, M. S.; Shaltev, M.; Shao, Z.; Shapiro, B.; Shawhan, P.; Shoemaker, D. H.; Sidery, T. L.; Siellez, K.; Siemens, X.; Sigg, D.; Simakov, D.; Singer, A.; Singer, L.; Singh, R.; Sintes, A. M.; Slagmolen, B. J. J.; Slutsky, J.; Smith, J. R.; Smith, M. R.; Smith, R. J. E.; Smith-Lefebvre, N. D.; Son, E. J.; Sorazu, B.; Souradeep, T.; Staley, A.; Stebbins, J.; Steinke, M.; Steinlechner, J.; Steinlechner, S.; Stephens, B. C.; Steplewski, S.; Stevenson, S.; Stone, R.; Stops, D.; Strain, K. A.; Straniero, N.; Strigin, S.; Sturani, R.; Stuver, A. L.; Summerscales, T. Z.; Susmithan, S.; Sutton, P. J.; Swinkels, B.; Tacca, M.; Talukder, D.; Tanner, D. B.; Tao, J.; Tarabrin, S. P.; Taylor, R.; Tellez, G.; Thirugnanasambandam, M. P.; Thomas, M.; Thomas, P.; Thorne, K. A.; Thorne, K. S.; Thrane, E.; Tiwari, V.; Tokmakov, K. V.; Tomlinson, C.; Tonelli, M.; Torres, C. V.; Torrie, C. I.; Travasso, F.; Traylor, G.; Tse, M.; Tshilumba, D.; Tuennermann, H.; Ugolini, D.; Unnikrishnan, C. S.; Urban, A. L.; Usman, S. A.; Vahlbruch, H.; Vajente, G.; Valdes, G.; Vallisneri, M.; van Beuzekom, M.; van den Brand, J. F. J.; Van Den Broeck, C.; van der Sluys, M. V.; van Heijningen, J.; van Veggel, A. A.; Vass, S.; Vasúth, M.; Vaulin, R.; Vecchio, A.; Vedovato, G.; Veitch, J.; Veitch, P. J.; Venkateswara, K.; Verkindt, D.; Vetrano, F.; Viceré, A.; Vincent-Finley, R.; Vinet, J.-Y.; Vitale, S.; Vo, T.; Vocca, H.; Vorvick, C.; Vousden, W. D.; Vyachanin, S. P.; Wade, A. R.; Wade, L.; Wade, M.; Walker, M.; Wallace, L.; Walsh, S.; Wang, M.; Wang, X.; Ward, R. L.; Was, M.; Weaver, B.; Wei, L.-W.; Weinert, M.; Weinstein, A. J.; Weiss, R.; Welborn, T.; Wen, L.; Wessels, P.; West, M.; Westphal, T.; Wette, K.; Whelan, J. T.; White, D. J.; Whiting, B. F.; Wiesner, K.; Wilkinson, C.; Williams, K.; Williams, L.; Williams, R.; Williams, T. D.; Williamson, A. R.; Willis, J. L.; Willke, B.; Wimmer, M.; Winkler, W.; Wipf, C. C.; Wiseman, A. G.; Wittel, H.; Woan, G.; Wolovick, N.; Worden, J.; Wu, Y.; Yablon, J.; Yakushin, I.; Yam, W.; Yamamoto, H.; Yancey, C. C.; Yang, H.; Yoshida, S.; Yvert, M.; ZadroŻny, A.; Zanolin, M.; Zendri, J.-P.; Zhang, Fan; Zhang, L.; Zhao, C.; Zhu, H.; Zhu, X. J.; Zucker, M. E.; Zuraw, S.; Zweizig, J.; Aptekar, R. L.; Atteia, J. L.; Cline, T.; Connaughton, V.; Frederiks, D. D.; Golenetskii, S. V.; Hurley, K.; Krimm, H. A.; Marisaldi, M.; Pal'shin, V. D.; Palmer, D.; Svinkin, D. S.; Terada, Y.; von Kienlin, A.; LIGO Scientific Collaboration; Virgo Collaboration; IPN Collaboration
2014-07-01
We present the results of a search for gravitational waves associated with 223 γ-ray bursts (GRBs) detected by the InterPlanetary Network (IPN) in 2005-2010 during LIGO's fifth and sixth science runs and Virgo's first, second, and third science runs. The IPN satellites provide accurate times of the bursts and sky localizations that vary significantly from degree scale to hundreds of square degrees. We search for both a well-modeled binary coalescence signal, the favored progenitor model for short GRBs, and for generic, unmodeled gravitational wave bursts. Both searches use the event time and sky localization to improve the gravitational wave search sensitivity as compared to corresponding all-time, all-sky searches. We find no evidence of a gravitational wave signal associated with any of the IPN GRBs in the sample, nor do we find evidence for a population of weak gravitational wave signals associated with the GRBs. For all IPN-detected GRBs, for which a sufficient duration of quality gravitational wave data are available, we place lower bounds on the distance to the source in accordance with an optimistic assumption of gravitational wave emission energy of 10-2M⊙c2 at 150 Hz, and find a median of 13 Mpc. For the 27 short-hard GRBs we place 90% confidence exclusion distances to two source models: a binary neutron star coalescence, with a median distance of 12 Mpc, or the coalescence of a neutron star and black hole, with a median distance of 22 Mpc. Finally, we combine this search with previously published results to provide a population statement for GRB searches in first-generation LIGO and Virgo gravitational wave detectors and a resulting examination of prospects for the advanced gravitational wave detectors.
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NASA Technical Reports Server (NTRS)
Aasi, J.; Abbott, B. P.; Abbott, R.; Abbott, T.; Abernathy, M. R.; Acernese, F.; Blackbum, L.; Camp, J. B.; Gehrels, N.; Graff, P. B.;
2014-01-01
We present the results of a search for gravitational waves associated with 223 gamma ray bursts (GRBs) detected by the InterPlanetary Network (IPN) in 2005-2010 during LIGO's fifth and sixth science runs and Virgo's first, second, and third science runs. The IPN satellites provide accurate times of the bursts and sky localizations that vary significantly from degree scale to hundreds of square degrees. We search for both a well-modeled binary coalescence signal, the favored progenitor model for short GRBs, and for generic, unmodeled gravitational wave bursts. Both searches use the event time and sky localization to improve the gravitational wave search sensitivity as compared to corresponding all-time, all-sky searches. We find no evidence of a gravitational wave signal associated with any of the IPN GRBs in the sample, nor do we find evidence for a population of weak gravitational wave signals associated with the GRBs. For all IPN-detected GRBs, for which a sufficient duration of quality gravitational wave data are available, we place lower bounds on the distance to the source in accordance with an optimistic assumption of gravitational wave emission energy of 10(exp-2) solar mass c(exp 2) at 150 Hz, and find a median of 13 Mpc. For the 27 short-hard GRBs we place 90% confidence exclusion distances to two source models: a binary neutron star coalescence, with a median distance of 12 Mpc, or the coalescence of a neutron star and black hole, with a median distance of 22 Mpc. Finally, we combine this search with previously published results to provide a population statement for GRB searches in first-generation LIGO and Virgo gravitational wave detectors and a resulting examination of prospects for the advanced gravitational wave detectors.
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Search for gravitational waves associated with γ-ray bursts detected by the interplanetary network.
Aasi, J; Abbott, B P; Abbott, R; Abbott, T; Abernathy, M R; Acernese, F; Ackley, K; Adams, C; Adams, T; Addesso, P; Adhikari, R X; Affeldt, C; Agathos, M; Aggarwal, N; Aguiar, O D; Ajith, P; Alemic, A; Allen, B; Allocca, A; Amariutei, D; Andersen, M; Anderson, R A; Anderson, S B; Anderson, W G; Arai, K; Araya, M C; Arceneaux, C; Areeda, J S; Ast, S; Aston, S M; Astone, P; Aufmuth, P; Augustus, H; Aulbert, C; Aylott, B E; Babak, S; Baker, P T; Ballardin, G; Ballmer, S W; Barayoga, J C; Barbet, M; Barish, B C; Barker, D; Barone, F; Barr, B; Barsotti, L; Barsuglia, M; Barton, M A; Bartos, I; Bassiri, R; Basti, A; Batch, J C; Bauchrowitz, J; Bauer, Th S; Baune, C; Bavigadda, V; Behnke, B; Bejger, M; Beker, M G; Belczynski, C; Bell, A S; Bell, C; Bergmann, G; Bersanetti, D; Bertolini, A; Betzwieser, J; Bilenko, I A; Billingsley, G; Birch, J; Biscans, S; Bitossi, M; Biwer, C; Bizouard, M A; Black, E; Blackburn, J K; Blackburn, L; Blair, D; Bloemen, S; Bock, O; Bodiya, T P; Boer, M; Bogaert, G; Bogan, C; Bond, C; Bondu, F; Bonelli, L; Bonnand, R; Bork, R; Born, M; Boschi, V; Bose, Sukanta; Bosi, L; Bradaschia, C; Brady, P R; Braginsky, V B; Branchesi, M; Brau, J E; Briant, T; Bridges, D O; Brillet, A; Brinkmann, M; Brisson, V; Brooks, A F; Brown, D A; Brown, D D; Brückner, F; Buchman, S; Buikema, A; Bulik, T; Bulten, H J; Buonanno, A; Burman, R; Buskulic, D; Buy, C; Cadonati, L; Cagnoli, G; Calderón Bustillo, J; Calloni, E; Camp, J B; Campsie, P; Cannon, K C; Canuel, B; Cao, J; Capano, C D; Carbognani, F; Carbone, L; Caride, S; Castaldi, G; Caudill, S; Cavaglià, M; Cavalier, F; Cavalieri, R; Celerier, C; Cella, G; Cepeda, C; Cesarini, E; Chakraborty, R; Chalermsongsak, T; Chamberlin, S J; Chao, S; Charlton, P; Chassande-Mottin, E; Chen, X; Chen, Y; Chincarini, A; Chiummo, A; Cho, H S; Cho, M; Chow, J H; Christensen, N; Chu, Q; Chua, S S Y; Chung, S; Ciani, G; Clara, F; Clark, D E; Clark, J A; Clayton, J H; Cleva, F; Coccia, E; Cohadon, P-F; Colla, A; Collette, C; Colombini, M; Cominsky, L; Constancio, M; Conte, A; Cook, D; Corbitt, T R; Cornish, N; Corsi, A; Costa, C A; Coughlin, M W; Coulon, J-P; Countryman, S; Couvares, P; Coward, D M; Cowart, M J; Coyne, D C; Coyne, R; Craig, K; Creighton, J D E; Croce, R P; Crowder, S G; Cumming, A; Cunningham, L; Cuoco, E; Cutler, C; Dahl, K; Dal Canton, T; Damjanic, M; Danilishin, S L; D'Antonio, S; Danzmann, K; Dattilo, V; Daveloza, H; Davier, M; Davies, G S; Daw, E J; Day, R; Dayanga, T; DeBra, D; Debreczeni, G; Degallaix, J; Deléglise, S; Del Pozzo, W; Denker, T; Dent, T; Dereli, H; Dergachev, V; De Rosa, R; DeRosa, R T; DeSalvo, R; Dhurandhar, S; Díaz, M; Dickson, J; Di Fiore, L; Di Lieto, A; Di Palma, I; Di Virgilio, A; Dolique, V; Dominguez, E; Donovan, F; Dooley, K L; Doravari, S; Douglas, R; Downes, T P; Drago, M; Drever, R W P; Driggers, J C; Du, Z; Ducrot, M; Dwyer, S; Eberle, T; Edo, T; Edwards, M; Effler, A; Eggenstein, H-B; Ehrens, P; Eichholz, J; Eikenberry, S S; Endrőczi, G; Essick, R; Etzel, T; Evans, M; Evans, T; Factourovich, M; Fafone, V; Fairhurst, S; Fan, X; Fang, Q; Farinon, S; Farr, B; Farr, W M; Favata, M; Fazi, D; Fehrmann, H; Fejer, M M; Feldbaum, D; Feroz, F; Ferrante, I; Ferreira, E C; Ferrini, F; Fidecaro, F; Finn, L S; Fiori, I; Fisher, R P; Flaminio, R; Fournier, J-D; Franco, S; Frasca, S; Frasconi, F; Frede, M; Frei, Z; Freise, A; Frey, R; Fricke, T T; Fritschel, P; Frolov, V V; Fulda, P; Fyffe, M; Gair, J R; Gammaitoni, L; Gaonkar, S; Garufi, F; Gehrels, N; Gemme, G; Gendre, B; Genin, E; Gennai, A; Ghosh, S; Giaime, J A; Giardina, K D; Giazotto, A; Gleason, J; Goetz, E; Goetz, R; Gondan, L; González, G; Gordon, N; Gorodetsky, M L; Gossan, S; Goßler, S; Gouaty, R; Gräf, C; Graff, P B; Granata, M; Grant, A; Gras, S; Gray, C; Greenhalgh, R J S; Gretarsson, A M; Groot, P; Grote, H; Grover, K; Grunewald, S; Guidi, G M; Guido, C J; Gushwa, K; Gustafson, E K; Gustafson, R; Ha, J; Hall, E D; Hamilton, W; Hammer, D; Hammond, G; Hanke, M; Hanks, J; Hanna, C; Hannam, M D; Hanson, J; Harms, J; Harry, G M; Harry, I W; Harstad, E D; Hart, M; Hartman, M T; Haster, C-J; Haughian, K; Heidmann, A; Heintze, M; Heitmann, H; Hello, P; Hemming, G; Hendry, M; Heng, I S; Heptonstall, A W; Heurs, M; Hewitson, M; Hild, S; Hoak, D; Hodge, K A; Hofman, D; Holt, K; Hopkins, P; Horrom, T; Hoske, D; Hosken, D J; Hough, J; Howell, E J; Hu, Y; Huerta, E; Hughey, B; Husa, S; Huttner, S H; Huynh, M; Huynh-Dinh, T; Idrisy, A; Ingram, D R; Inta, R; Islas, G; Isogai, T; Ivanov, A; Iyer, B R; Izumi, K; Jacobson, M; Jang, H; Jaranowski, P; Ji, Y; Jiménez-Forteza, F; Johnson, W W; Jones, D I; Jones, R; Jonker, R J G; Ju, L; Haris, K; Kalmus, P; Kalogera, V; Kandhasamy, S; Kang, G; Kanner, J B; Karlen, J; Kasprzack, M; Katsavounidis, E; Katzman, W; Kaufer, H; Kaufer, S; Kaur, T; Kawabe, K; Kawazoe, F; Kéfélian, F; Keiser, G M; Keitel, D; Kelley, D B; Kells, W; Keppel, D G; Khalaidovski, A; Khalili, F Y; Khazanov, E A; Kim, C; Kim, K; Kim, N G; Kim, N; Kim, S; Kim, Y-M; King, E J; King, P J; Kinzel, D L; Kissel, J S; Klimenko, S; Kline, J; Koehlenbeck, S; Kokeyama, K; Kondrashov, V; Koranda, S; Korth, W Z; Kowalska, I; Kozak, D B; Kringel, V; Krishnan, B; Królak, A; Kuehn, G; Kumar, A; Kumar, D Nanda; Kumar, P; Kumar, R; Kuo, L; Kutynia, A; Lam, P K; Landry, M; Lantz, B; Larson, S; Lasky, P D; Lazzarini, A; Lazzaro, C; Leaci, P; Leavey, S; Lebigot, E O; Lee, C H; Lee, H K; Lee, H M; Lee, J; Lee, P J; Leonardi, M; Leong, J R; Leonor, I; Le Roux, A; Leroy, N; Letendre, N; Levin, Y; Levine, B; Lewis, J; Li, T G F; Libbrecht, K; Libson, A; Lin, A C; Littenberg, T B; Lockerbie, N A; Lockett, V; Lodhia, D; Loew, K; Logue, J; Lombardi, A L; Lopez, E; Lorenzini, M; Loriette, V; Lormand, M; Losurdo, G; Lough, J; Lubinski, M J; Lück, H; Lundgren, A P; Ma, Y; Macdonald, E P; MacDonald, T; Machenschalk, B; MacInnis, M; Macleod, D M; Magaña-Sandoval, F; Magee, R; Mageswaran, M; Maglione, C; Mailand, K; Majorana, E; Maksimovic, I; Malvezzi, V; Man, N; Manca, G M; Mandel, I; Mandic, V; Mangano, V; Mangini, N M; Mansell, G; Mantovani, M; Marchesoni, F; Marion, F; Márka, S; Márka, Z; Markosyan, A; Maros, E; Marque, J; Martelli, F; Martin, I W; Martin, R M; Martinelli, L; Martynov, D; Marx, J N; Mason, K; Masserot, A; Massinger, T J; Matichard, F; Matone, L; Mavalvala, N; May, G; Mazumder, N; Mazzolo, G; McCarthy, R; McClelland, D E; McGuire, S C; McIntyre, G; McIver, J; McLin, K; Meacher, D; Meadors, G D; Mehmet, M; Meidam, J; Meinders, M; Melatos, A; Mendell, G; Mercer, R A; Meshkov, S; Messenger, C; Meyer, M S; Meyers, P M; Mezzani, F; Miao, H; Michel, C; Mikhailov, E E; Milano, L; Miller, J; Minenkov, Y; Mingarelli, C M F; Mishra, C; Mitra, S; Mitrofanov, V P; Mitselmakher, G; Mittleman, R; Moe, B; Moggi, A; Mohan, M; Mohapatra, S R P; Moraru, D; Moreno, G; Morgado, N; Morriss, S R; Mossavi, K; Mours, B; Mow-Lowry, C M; Mueller, C L; Mueller, G; Mukherjee, S; Mullavey, A; Munch, J; Murphy, D; Murray, P G; Mytidis, A; Nagy, M F; Nardecchia, I; Naticchioni, L; Nayak, R K; Necula, V; Nelemans, G; Neri, I; Neri, M; Newton, G; Nguyen, T; Nielsen, A B; Nissanke, S; Nitz, A H; Nocera, F; Nolting, D; Normandin, M E N; Nuttall, L K; Ochsner, E; O'Dell, J; Oelker, E; Oh, J J; Oh, S H; Ohme, F; Omar, S; Oppermann, P; Oram, R; O'Reilly, B; Ortega, W; O'Shaughnessy, R; Osthelder, C; Ottaway, D J; Ottens, R S; Overmier, H; Owen, B J; Padilla, C; Pai, A; Palashov, O; Palomba, C; Pan, H; Pan, Y; Pankow, C; Paoletti, F; Papa, M A; Paris, H; Pasqualetti, A; Passaquieti, R; Passuello, D; Pedraza, M; Pele, A; Penn, S; Perreca, A; Phelps, M; Pichot, M; Pickenpack, M; Piergiovanni, F; Pierro, V; Pinard, L; Pinto, I M; Pitkin, M; Poeld, J; Poggiani, R; Poteomkin, A; Powell, J; Prasad, J; Predoi, V; Premachandra, S; Prestegard, T; Price, L R; Prijatelj, M; Privitera, S; Prodi, G A; Prokhorov, L; Puncken, O; Punturo, M; Puppo, P; Pürrer, M; Qin, J; Quetschke, V; Quintero, E; Quitzow-James, R; Raab, F J; Rabeling, D S; Rácz, I; Radkins, H; Raffai, P; Raja, S; Rajalakshmi, G; Rakhmanov, M; Ramet, C; Ramirez, K; 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Souradeep, T; Staley, A; Stebbins, J; Steinke, M; Steinlechner, J; Steinlechner, S; Stephens, B C; Steplewski, S; Stevenson, S; Stone, R; Stops, D; Strain, K A; Straniero, N; Strigin, S; Sturani, R; Stuver, A L; Summerscales, T Z; Susmithan, S; Sutton, P J; Swinkels, B; Tacca, M; Talukder, D; Tanner, D B; Tao, J; Tarabrin, S P; Taylor, R; Tellez, G; Thirugnanasambandam, M P; Thomas, M; Thomas, P; Thorne, K A; Thorne, K S; Thrane, E; Tiwari, V; Tokmakov, K V; Tomlinson, C; Tonelli, M; Torres, C V; Torrie, C I; Travasso, F; Traylor, G; Tse, M; Tshilumba, D; Tuennermann, H; Ugolini, D; Unnikrishnan, C S; Urban, A L; Usman, S A; Vahlbruch, H; Vajente, G; Valdes, G; Vallisneri, M; van Beuzekom, M; van den Brand, J F J; Van Den Broeck, C; van der Sluys, M V; van Heijningen, J; van Veggel, A A; Vass, S; Vasúth, M; Vaulin, R; Vecchio, A; Vedovato, G; Veitch, J; Veitch, P J; Venkateswara, K; Verkindt, D; Vetrano, F; Viceré, A; Vincent-Finley, R; Vinet, J-Y; Vitale, S; Vo, T; Vocca, H; Vorvick, C; Vousden, W D; Vyachanin, S P; Wade, A R; Wade, L; Wade, M; Walker, M; Wallace, L; Walsh, S; Wang, M; Wang, X; Ward, R L; Was, M; Weaver, B; Wei, L-W; Weinert, M; Weinstein, A J; Weiss, R; Welborn, T; Wen, L; Wessels, P; West, M; Westphal, T; Wette, K; Whelan, J T; White, D J; Whiting, B F; Wiesner, K; Wilkinson, C; Williams, K; Williams, L; Williams, R; Williams, T D; Williamson, A R; Willis, J L; Willke, B; Wimmer, M; Winkler, W; Wipf, C C; Wiseman, A G; Wittel, H; Woan, G; Wolovick, N; Worden, J; Wu, Y; Yablon, J; Yakushin, I; Yam, W; Yamamoto, H; Yancey, C C; Yang, H; Yoshida, S; Yvert, M; Zadrożny, A; Zanolin, M; Zendri, J-P; Zhang, Fan; Zhang, L; Zhao, C; Zhu, H; Zhu, X J; Zucker, M E; Zuraw, S; Zweizig, J; Aptekar, R L; Atteia, J L; Cline, T; Connaughton, V; Frederiks, D D; Golenetskii, S V; Hurley, K; Krimm, H A; Marisaldi, M; Pal'shin, V D; Palmer, D; Svinkin, D S; Terada, Y; von Kienlin, A
2014-07-04
We present the results of a search for gravitational waves associated with 223 γ-ray bursts (GRBs) detected by the InterPlanetary Network (IPN) in 2005-2010 during LIGO's fifth and sixth science runs and Virgo's first, second, and third science runs. The IPN satellites provide accurate times of the bursts and sky localizations that vary significantly from degree scale to hundreds of square degrees. We search for both a well-modeled binary coalescence signal, the favored progenitor model for short GRBs, and for generic, unmodeled gravitational wave bursts. Both searches use the event time and sky localization to improve the gravitational wave search sensitivity as compared to corresponding all-time, all-sky searches. We find no evidence of a gravitational wave signal associated with any of the IPN GRBs in the sample, nor do we find evidence for a population of weak gravitational wave signals associated with the GRBs. For all IPN-detected GRBs, for which a sufficient duration of quality gravitational wave data are available, we place lower bounds on the distance to the source in accordance with an optimistic assumption of gravitational wave emission energy of 10(-2)M⊙c(2) at 150 Hz, and find a median of 13 Mpc. For the 27 short-hard GRBs we place 90% confidence exclusion distances to two source models: a binary neutron star coalescence, with a median distance of 12 Mpc, or the coalescence of a neutron star and black hole, with a median distance of 22 Mpc. Finally, we combine this search with previously published results to provide a population statement for GRB searches in first-generation LIGO and Virgo gravitational wave detectors and a resulting examination of prospects for the advanced gravitational wave detectors.
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Collaborative Wideband Compressed Signal Detection in Interplanetary Internet
NASA Astrophysics Data System (ADS)
Wang, Yulin; Zhang, Gengxin; Bian, Dongming; Gou, Liang; Zhang, Wei
2014-07-01
As the development of autonomous radio in deep space network, it is possible to actualize communication between explorers, aircrafts, rovers and satellites, e.g. from different countries, adopting different signal modes. The first mission to enforce the autonomous radio is to detect signals of the explorer autonomously without disturbing the original communication. This paper develops a collaborative wideband compressed signal detection approach for InterPlaNetary (IPN) Internet where there exist sparse active signals in the deep space environment. Compressed sensing (CS) can be utilized by exploiting the sparsity of IPN Internet communication signal, whose useful frequency support occupies only a small portion of an entirely wide spectrum. An estimate of the signal spectrum can be obtained by using reconstruction algorithms. Against deep space shadowing and channel fading, multiple satellites collaboratively sense and make a final decision according to certain fusion rule to gain spatial diversity. A couple of novel discrete cosine transform (DCT) and walsh-hadamard transform (WHT) based compressed spectrum detection methods are proposed which significantly improve the performance of spectrum recovery and signal detection. Finally, extensive simulation results are presented to show the effectiveness of our proposed collaborative scheme for signal detection in IPN Internet. Compared with the conventional discrete fourier transform (DFT) based method, our DCT and WHT based methods reduce computational complexity, decrease processing time, save energy and enhance probability of detection.
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Controlled release of therapeutics using interpenetrating polymeric networks.
Aminabhavi, Tejraj M; Nadagouda, Mallikarjuna N; More, Uttam A; Joshi, Shrinivas D; Kulkarni, Venkatrao H; Noolvi, Malleshappa N; Kulkarni, Padmakar V
2015-04-01
The ever-increasing developments in pharmaceutical formulations have led to the widespread use of biodegradable polymers in various forms and configurations. In particular, interpenetrating network (IPN) and semi-IPN polymer structures that are capable of releasing drugs in a controlled manner have gained much wider importance in recent years. Recently, IPNs and semi-IPNs have emerged as innovative materials of choice in controlled release (CR) of drugs as the release from these systems depends on pH of the media and temperature in addition to the nature of the system. These networks can be prepared as smart hydrogels following chemical or physical crosslinking methods to show remarkable drug release patterns compared to single polymer systems. A large number of IPNs and semi-IPNs have been reported in the literature. The present review is focused on the preparation methods and their CR properties with reference to anticancer, anti-asthmatic, antibiotic, anti-inflammatory, anti-tuberculosis and antihypertensive drugs, as majority of these drugs have been reported to be the ideal choices for using IPNs and semi-IPNs.
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Zhang, Yeshun; Liu, Jia; Huang, Lei; Wang, Zheng; Wang, Lin
2015-07-24
Although alginate hydrogels have been extensively studied for tissue engineering applications, their utilization is limited by poor mechanical strength, rapid drug release, and a lack of cell adhesive ability. Aiming to improve these properties, we employ the interpenetrating hydrogel design rationale. Using alginate and sericin (a natural protein with many unique properties and a major component of silkworm silk), we develop an interpenetrating polymer network (IPN) hydrogel comprising interwoven sericin and alginate double networks. By adjusting the sericin-to-alginate ratios, IPNs' mechanical strength can be adjusted to meet stiffness requirements for various tissue repairs. The IPNs with high sericin content show increased stability during degradation, avoiding pure alginate's early collapse. These IPNs have high swelling ratios, benefiting various applications such as drug delivery. The IPNs sustain controlled drug release with the adjustable rates. Furthermore, these IPNs are adhesive to cells, supporting cell proliferation, long-term survival and migration. Notably, the IPNs inherit sericin's photoluminescent property, enabling bioimaging in vivo. Together, our study indicates that the sericin-alginate IPN hydrogels may serve as a versatile platform for delivering cells and drugs, and suggests that sericin may be a building block broadly applicable for generating IPN networks with other biomaterials for diverse tissue engineering applications.
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Investigation of primordial black hole bursts using interplanetary network gamma-ray bursts
Ukwatta, Tilan Niranjan; Hurley, Kevin; MacGibbon, Jane H.; ...
2016-07-25
The detection of a gamma-ray burst (GRB) in the solar neighborhood would have very important implications for GRB phenomenology. The leading theories for cosmological GRBs would not be able to explain such events. The final bursts of evaporating primordial black holes (PBHs), however, would be a natural explanation for local GRBs. We present a novel technique that can constrain the distance to GRBs using detections from widely separated, non-imaging spacecraft. This method can determine the actual distance to the burst if it is local. We applied this method to constrain distances to a sample of 36 short-duration GRBs detected bymore » the Interplanetary Network (IPN) that show observational properties that are expected from PBH evaporations. These bursts have minimum possible distances in the 10 13–10 18 cm (7–10 5 au) range, which are consistent with the expected PBH energetics and with a possible origin in the solar neighborhood, although none of the bursts can be unambiguously demonstrated to be local. Furthermore, assuming that these bursts are real PBH events, we estimate lower limits on the PBH burst evaporation rate in the solar neighborhood.« less
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Zhang, Yeshun; Liu, Jia; Huang, Lei; Wang, Zheng; Wang, Lin
2015-01-01
Although alginate hydrogels have been extensively studied for tissue engineering applications, their utilization is limited by poor mechanical strength, rapid drug release, and a lack of cell adhesive ability. Aiming to improve these properties, we employ the interpenetrating hydrogel design rationale. Using alginate and sericin (a natural protein with many unique properties and a major component of silkworm silk), we develop an interpenetrating polymer network (IPN) hydrogel comprising interwoven sericin and alginate double networks. By adjusting the sericin-to-alginate ratios, IPNs’ mechanical strength can be adjusted to meet stiffness requirements for various tissue repairs. The IPNs with high sericin content show increased stability during degradation, avoiding pure alginate’s early collapse. These IPNs have high swelling ratios, benefiting various applications such as drug delivery. The IPNs sustain controlled drug release with the adjustable rates. Furthermore, these IPNs are adhesive to cells, supporting cell proliferation, long-term survival and migration. Notably, the IPNs inherit sericin’s photoluminescent property, enabling bioimaging in vivo. Together, our study indicates that the sericin-alginate IPN hydrogels may serve as a versatile platform for delivering cells and drugs, and suggests that sericin may be a building block broadly applicable for generating IPN networks with other biomaterials for diverse tissue engineering applications. PMID:26205586
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NASA Astrophysics Data System (ADS)
Zhang, Yeshun; Liu, Jia; Huang, Lei; Wang, Zheng; Wang, Lin
2015-07-01
Although alginate hydrogels have been extensively studied for tissue engineering applications, their utilization is limited by poor mechanical strength, rapid drug release, and a lack of cell adhesive ability. Aiming to improve these properties, we employ the interpenetrating hydrogel design rationale. Using alginate and sericin (a natural protein with many unique properties and a major component of silkworm silk), we develop an interpenetrating polymer network (IPN) hydrogel comprising interwoven sericin and alginate double networks. By adjusting the sericin-to-alginate ratios, IPNs’ mechanical strength can be adjusted to meet stiffness requirements for various tissue repairs. The IPNs with high sericin content show increased stability during degradation, avoiding pure alginate’s early collapse. These IPNs have high swelling ratios, benefiting various applications such as drug delivery. The IPNs sustain controlled drug release with the adjustable rates. Furthermore, these IPNs are adhesive to cells, supporting cell proliferation, long-term survival and migration. Notably, the IPNs inherit sericin’s photoluminescent property, enabling bioimaging in vivo. Together, our study indicates that the sericin-alginate IPN hydrogels may serve as a versatile platform for delivering cells and drugs, and suggests that sericin may be a building block broadly applicable for generating IPN networks with other biomaterials for diverse tissue engineering applications.
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NASA Astrophysics Data System (ADS)
Plesse, C.; Khaldi, A.; Wang, Q.; Cattan, E.; Teyssié, D.; Chevrot, C.; Vidal, F.
2011-12-01
In recent years, numerous studies on electro-active polymer (EAP) actuators have been reported. One promising technology is the elaboration of electronic conducting polymer-based actuators with interpenetrating polymer network (IPNs) architecture. In this study, the synthesis and characterisation of conducting IPNs for actuator applications is described. The IPNs are synthesised from polyethylene oxide (PEO) and polytetrahydrofurane (PTHF) networks in which the conducting polymer (poly(3,4-ethylenedioxythiophene)) is incorporated. In a first step, PEO/PTHF IPNs were prepared via an 'in situ' process using poly(ethylene glycol) methacrylate and dimethacrylate and hydroxytelechelic PTHF as starting materials. The IPN mechanical properties were examined by DMA and tensile strength tests. N-ethylmethylimidazolium bis(trifluoromethanesulfonyl)imide (EMITFSI) swollen PEO/PTHF IPNs show ionic conductivities up to 10-3 S cm-1 at 30 °C. In a second step, the conducting IPN actuators were prepared by oxidative polymerisation of 3,4-ethylenedioxithiophene (EDOT) using FeCl3 as an oxidising agent within the PEO/PTHF IPN host matrix. The frequency response performance of the bending conducting IPN actuator was then evaluated. The resulting actuator exhibits a mechanical resonance frequency of up to 125 Hz with 0.75% strain for an applied potential of ± 5 V.
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Akpalo, E; Bidault, L; Boissière, M; Vancaeyzeele, C; Fichet, O; Larreta-Garde, V
2011-06-01
Interpenetrating polymer network (IPN) architectures were conceived to improve the mechanical properties of a fibrin gel. Conditions allowing an enzymatic reaction to create one of the two networks in IPN architecture were included in the synthesis pathway. Two IPN series were carried out, starting from two polyethylene oxide (PEO) network precursors leading to different cross-linking densities of the PEO phase. The fibrin concentration varied from 5 to 20 wt.% in each series. The behavior of these materials during dehydration/hydration cycles was also studied. The mechanical properties of the resulting IPN were characterized in the wet and dry states. These self-supported biomaterials combine the properties of both a protein gel and a synthetic polymer. Finally, cells were grown on PEO/fibrin IPN, indicating that they are non-cytotoxic. Copyright © 2011 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.
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Electroactive semi-interpenetrating polymer networks architecture with tunable IR reflectivity
NASA Astrophysics Data System (ADS)
Chevrot, C.; Teyssié, D.; Verge, P.; Goujon, L.; Tran-Van, F.; Vidal, F.; Aubert, P. H.; Peralta, S.; Sauques, L.
2011-04-01
A promising alternative of multi-layered devices showing electrochromic properties results from the design of a self-supported semi-interpenetrating polymer network (semi-IPN) including an electronic conductive polymer (ECP) formed within. The formation of the ECP in the network has already been described by oxidative polymerization using iron trichloride as an oxidant and leading to conducting semi-IPN with mixed electronic and ionic conductivities as well as convenient mechanical properties. This presentation relates to the elaboration of such semi-IPN using polyethyleneoxide (PEO) network or a PEO/NBR (Nitrile Butadiene Rubber) IPN in which a linear poly (3,4-ethylenedioxythiophene) (PEDOT) is formed symmetrically and selectively as very thin layers very next to the two main faces of the film matrix. PEO/PEDOT semi-IPNs lead to interesting optical reflective properties in the IR between 0.8 and 25 μm. Reflectance contrasts up to 35 % is observed when, after swelling in an ionic liquid, a low voltage is applied between the two main faces of the film. However the low flexibility and brittleness of the film and a slow degradation in air at temperature up from 60°C prompted to replace the PEO matrix by a flexible PEO/NBR IPN one. Indeed, the combination of NBR and PEO in an IPN leads to materials possessing flexible properties, good ionic conductivity at 25°C as well as a better resistance to thermal ageing. Finally, NBR/PEO/PEDOT semi-IPNs allow observing comparable reflectance contrast in the IR range than those shown by PEO/PEDOT semi-IPNs.
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Superparamagnetic IPN gels of carrageenan/PHEMA excelling in shape retention.
Tsuru, Takahiro; Sugimura, Kazuki; Nishio, Yoshiyuki
2017-12-15
Iron oxide nanoparticles-incorporated carrageenan (CAR)/PHEMA composites of interpenetrating network (IPN) type were successfully prepared by in situ ferrite synthesis in the polymer network. The IPN structure was constructed at CAR/PHEMA compositions of 15/85 and 40/60 (wt/wt) by polymerization and cross-linking of 2-hydroxyethylmethacrylate as an impregnating solvent of CAR gels. As a result of this IPN construction, the composites were firm and showed a good shape-retentivity in their gelatinous state. SQUID magnetometry and X-ray diffractometry were conducted for evaluation of the magnetic property of the inorganic-hybridized IPN composites. Magnetite particles with 10-30nm sizes were distributed inside the IPNs treated with the repeatable ferrite synthesis; thereby, the hybrids displayed a superparamagnetic character at ambient temperature. Specifically, the 40/60 CAR/PHEMA IPN imparted a practically passable value (10-15emu (g sample) -1 ) of saturation magnetization. The present IPN system offers a potential for application as a biocompatible magnetic material used in hydro-surroundings. Copyright © 2017 Elsevier Ltd. All rights reserved.
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Interpenetrating Polymer Networks as Innovative Drug Delivery Systems
Lohani, Alka; Singh, Garima; Bhattacharya, Shiv Sankar; Verma, Anurag
2014-01-01
Polymers have always been valuable excipients in conventional dosage forms, also have shown excellent performance into the parenteral arena, and are now capable of offering advanced and sophisticated functions such as controlled drug release and drug targeting. Advances in polymer science have led to the development of several novel drug delivery systems. Interpenetrating polymer networks (IPNs) have shown superior performances over the conventional individual polymers and, consequently, the ranges of applications have grown rapidly for such class of materials. The advanced properties of IPNs like swelling capacity, stability, biocompatibility, nontoxicity and biodegradability have attracted considerable attention in pharmaceutical field especially in delivering bioactive molecules to the target site. In the past few years various research reports on the IPN based delivery systems showed that these carriers have emerged as a novel carrier in controlled drug delivery. The present review encompasses IPNs, their types, method of synthesis, factors which affects the morphology of IPNs, extensively studied IPN based drug delivery systems, and some natural polymers widely used for IPNs. PMID:24949205
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Guar gum based biodegradable, antibacterial and electrically conductive hydrogels.
Kaith, Balbir S; Sharma, Reena; Kalia, Susheel
2015-04-01
Guar gum-polyacrylic acid-polyaniline based biodegradable electrically conductive interpenetrating network (IPN) structures were prepared through a two-step aqueous polymerization. Hexamine and ammonium persulfate (APS) were used as a cross linker-initiator system to crosslink the poly(AA) chains on Guar gum (Ggum) backbone. Optimum reaction conditions for maximum percentage swelling (7470.23%) were time (min) = 60; vacuum (mmHg) = 450; pH = 7.0; solvent (mL) = 27.5; [APS] (mol L(-1)) = 0.306 × 10(-1); [AA] (mol L(-1)) = 0.291 × 10(-3) and [hexamine] (mol L(-1))=0.356 × 10(-1). The semi-interpenetrating networks (semi-IPNs) were converted into IPNs through impregnation of polyaniline chains under acidic and neutral conditions. Fourier transform infra-red spectroscopy (FTIR), thermogravimetric analysis (TGA) and scanning electron microscopy (SEM) techniques were used to characterize the semi-IPNs and IPNs. Synthesized semi-IPNs and IPNs were further evaluated for moisture retention in different soils, antibacterial and biodegradation behavior. Copyright © 2015 Elsevier B.V. All rights reserved.
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Kong, Xiaohua; Narine, Suresh S
2008-08-01
Sequential interpenetrating polymer networks (IPNs) were prepared using polyurethane produced from a canola oil based polyol with primary terminal functional groups and poly(methyl methacrylate) (PMMA). The properties of the material were studied and compared to the IPNs made from commercial castor oil using dynamic mechanical analysis, differential scanning calorimetry, as well as tensile measurements. The morphology of the IPNs was investigated using scanning electron microscopy and transmission electron microscopy. The chemical diversity of the starting materials allowed the evaluation of the effects of dangling chains and graftings on the properties of the IPNs. The polymerization process of canola oil based IPNs was accelerated because of the utilization of polyol with primary functional groups, which efficiently lessened the effect of dangling chains and yielded a higher degree of phase mixing. The mechanical properties of canola oil based IPNs containing more than 75 wt % PMMA were comparable to the corresponding castor oil based IPNs; both were superior to those of the constituent polymers due to the finely divided rubber and plastic combination structures in these IPNs. However, when PMMA content was less than 65 wt %, canola oil based IPNs exhibited a typical mechanical behavior of rigid plastics, whereas castor oil based IPNs showed a typical mechanical behavior of soft rubber. It is proposed that these new IPN materials with high performance prepared from alternative renewable resources can prove to be valuable substitutes for existing materials in various applications.
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Application of organic IR788-loaded semi-interpenetrating network dyes for photoacoustic imaging
NASA Astrophysics Data System (ADS)
Phuc Nguyen, Van; Kim, Hyejin; Kang, Mingyeong; Kwak, Minseok; Kang, Hyun Wook
2017-07-01
In this study, we present the feasibility of a biocompatible Lumogen® IR788-loaded polymeric nanoparticle (NP) as a novel photoabsorbing agent for photoacoustic (PA) imaging. The NP was fabricated through a semi-interpenetrating network (sIPN) within the core of F127 resulting in IR788-sIPN formation. To evaluate the PA sensitivity of the material, tubing phantoms were injected with various concentrations of IR788-sIPN, and H1975 lung-tumor-bearing mice were intratumorally injected with IR788-sIPN. Compared with the background, the PA contrast was enhanced up to 80 and 40% in the phantom and in vivo experiments, respectively. IR788-sIPN can be a feasible IR-absorbing material for early cancer detection.
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Gsib, Olfat; Duval, Jean-Luc; Goczkowski, Mathieu; Deneufchatel, Marie; Fichet, Odile; Larreta-Garde, Véronique; Bencherif, Sidi Ahmed; Egles, Christophe
2017-12-10
Interpenetrating polymer networks (IPNs) have gained great attention for a number of biomedical applications due to their improved properties compared to individual components alone. In this study, we investigated the capacity of newly-developed naturally-derived IPNs as potential biomaterials for tissue engineering. These IPNs combine the biologic properties of a fibrous fibrin network polymerized at the nanoscale and the mechanical stability of polyethylene oxide (PEO). First, we assessed their cytotoxicity in vitro on L929 fibroblasts. We further evaluated their biocompatibility ex vivo with a chick embryo organotypic culture model. Subcutaneous implantations of the matrices were subsequently conducted on nude mice to investigate their biocompatibility in vivo. Our preliminary data highlighted that our biomaterials were non-cytotoxic (viability above 90%). The organotypic culture showed that the IPN matrices induced higher cell adhesion (across all the explanted organ tissues) and migration (skin, intestine) than the control groups, suggesting the advantages of using a biomimetic, yet mechanically-reinforced IPN-based matrix. We observed no major inflammatory response up to 12 weeks post implantation. All together, these data suggest that these fibrin-based IPNs are promising biomaterials for tissue engineering.
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Gsib, Olfat; Duval, Jean-Luc; Goczkowski, Mathieu; Deneufchatel, Marie; Fichet, Odile; Larreta-Garde, Véronique
2017-01-01
Interpenetrating polymer networks (IPNs) have gained great attention for a number of biomedical applications due to their improved properties compared to individual components alone. In this study, we investigated the capacity of newly-developed naturally-derived IPNs as potential biomaterials for tissue engineering. These IPNs combine the biologic properties of a fibrous fibrin network polymerized at the nanoscale and the mechanical stability of polyethylene oxide (PEO). First, we assessed their cytotoxicity in vitro on L929 fibroblasts. We further evaluated their biocompatibility ex vivo with a chick embryo organotypic culture model. Subcutaneous implantations of the matrices were subsequently conducted on nude mice to investigate their biocompatibility in vivo. Our preliminary data highlighted that our biomaterials were non-cytotoxic (viability above 90%). The organotypic culture showed that the IPN matrices induced higher cell adhesion (across all the explanted organ tissues) and migration (skin, intestine) than the control groups, suggesting the advantages of using a biomimetic, yet mechanically-reinforced IPN-based matrix. We observed no major inflammatory response up to 12 weeks post implantation. All together, these data suggest that these fibrin-based IPNs are promising biomaterials for tissue engineering. PMID:29232876
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Robust solid polymer electrolyte for conducting IPN actuators
NASA Astrophysics Data System (ADS)
Festin, Nicolas; Maziz, Ali; Plesse, Cédric; Teyssié, Dominique; Chevrot, Claude; Vidal, Frédéric
2013-10-01
Interpenetrating polymer networks (IPNs) based on nitrile butadiene rubber (NBR) as first component and poly(ethylene oxide) (PEO) as second component were synthesized and used as a solid polymer electrolyte film in the design of a mechanically robust conducting IPN actuator. IPN mechanical properties and morphologies were mainly investigated by dynamic mechanical analysis and transmission electron microscopy. For 1-ethyl-3-methylimidazolium bis-(trifluoromethylsulfonyl)-imide (EMITFSI) swollen IPNs, conductivity values are close to 1 × 10-3 S cm-1 at 25 ° C. Conducting IPN actuators have been synthesized by chemical polymerization of 3,4-ethylenedioxythiophene (EDOT) within the PEO/NBR IPN. A pseudo-trilayer configuration has been obtained with PEO/NBR IPN sandwiched between two interpenetrated PEDOT electrodes. The robust conducting IPN actuators showed a free strain of 2.4% and a blocking force of 30 mN for a low applied potential of ±2 V.
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NASA Technical Reports Server (NTRS)
Pater, Ruth H.
1990-01-01
A simultaneous semi-interpenetrating polymer network (semi-IPN) concept is presented which combines easy-to-process, but brittle, thermosetting polyimides with tough, but difficult to process, linear thermoplastic polyimides. The combination results in a semi-IPN with the easy processability of a thermoset and good toughness of a thermoplastic. Four simultaneous semi-IPN systems were developed from commercially available NR-150B2 combined with each of the four Thermid materials (LR-600, AL-600, MC-600, and FA-700). It is concluded that there is a significant improvement in resin fracture toughness of Thermid-polyimide-based semi-IPN systems and some improvement in composite microcracking resistance compared to Thermid LR-600. Excellent composite mechanical properties have been achieved. These new semi-IPN materials have the potential to be used as composite matrices, adhesives, and molding materials.
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NASA Astrophysics Data System (ADS)
Fahrul Hassan, Mohd; Jamri, Azmil; Nawawi, Azli; Zaini Yunos, Muhamad; Fauzi Ahmad, Md; Adzila, Sharifah; Nasrull Abdol Rahman, Mohd
2017-08-01
The main purpose of this study is to investigate the performance of a driven fan design made by Polyester/Epoxy interpenetrate polymer network (IPN) material that specifically used for turbocharger compressor. Polyester/Epoxy IPN is polymer plastics that was used as replacements for traditional polymers and has been widely used in a variety of applications because of their limitless conformations. Simulation based on several parameters which are air pressure, air velocity and air temperature have been carried out for a driven fan design performance of two different materials, aluminum alloy (existing driven fan design) and Polyester/Epoxy IPN using SolidWorks Flow Simulation software. Results from both simulations were analyzed and compared where both materials show similar performance in terms of air pressure and air velocity due to similar geometric and dimension, but Polyester/Epoxy IPN produces lower air temperature than aluminum alloy. This study shows a preliminary result of the potential Polyester/Epoxy IPN to be used as a driven fan design material. In the future, further studies will be conducted on detail simulation and experimental analysis.
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3D printing of an interpenetrating network hydrogel material with tunable viscoelastic properties.
Bootsma, Katherine; Fitzgerald, Martha M; Free, Brandon; Dimbath, Elizabeth; Conjerti, Joe; Reese, Greg; Konkolewicz, Dominik; Berberich, Jason A; Sparks, Jessica L
2017-06-01
Interpenetrating network (IPN) hydrogel materials are recognized for their unique mechanical properties. While IPN elasticity and toughness properties have been explored in previous studies, the factors that impact the time-dependent stress relaxation behavior of IPN materials are not well understood. Time-dependent (i.e. viscoelastic) mechanical behavior is a critical design parameter in the development of materials for a variety of applications, such as medical simulation devices, flexible substrate materials, cellular mechanobiology substrates, or regenerative medicine applications. This study reports a novel technique for 3D printing alginate-polyacrylamide IPN gels with tunable elastic and viscoelastic properties. The viscoelastic stress relaxation behavior of the 3D printed alginate-polyacrylamide IPN hydrogels was influenced most strongly by varying the concentration of the acrylamide cross-linker (MBAA), while the elastic modulus was affected most by varying the concentration of total monomer material. The material properties of our 3D printed IPN constructs were consistent with those reported in the biomechanics literature for soft tissues such as skeletal muscle, cardiac muscle, skin and subcutaneous tissue. Copyright © 2017 Elsevier Ltd. All rights reserved.
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Kong, Xiaohua; Narine, Suresh S
2008-05-01
Sequential interpenetrating polymer networks (IPNs) were prepared using polyurethane (PUR) synthesized from canola oil-based polyol with terminal primary functional groups and poly(methyl methacrylate) (PMMA). The properties of the material were evaluated by dynamic mechanical analysis (DMA), differential scanning calorimetry (DSC), and modulated differential scanning calorimetry (MDSC), as well as tensile properties measurements. The morphology of the IPNs was investigated using scanning electron microscopy (SEM) and MDSC. A five-phase morphology, that is, sol phase, PUR-rich phase, PUR-rich interphase, PMMA-rich interphase, and PMMA-rich phase, was observed for all the IPNs by applying a new quantitative method based on the measurement of the differential of reversing heat capacity versus temperature from MDSC, although not confirmed by SEM, most likely due to resolution restrictions. NCO/OH molar ratios (cross-linking density) and compositional variations of PUR/PMMA both affected the thermal properties and phase behaviors of the IPNs. Higher degrees of mixing occurred for the IPN with higher NCO/OH molar ratio (2.0/1.0) at PUR concentration of 25 wt %, whereas for the IPN with lower NCO/OH molar ratio (1.6/1.0), higher degrees of mixing occurred at PUR concentration of 35 wt %. The mechanical properties of the IPNs were superior to those of the constituent polymers due to the finely divided rubber and plastic combination structures in these IPNs.
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Rennerfeldt, Deena A; Renth, Amanda N; Talata, Zsolt; Gehrke, Stevin H; Detamore, Michael S
2013-11-01
Hydrogels are attractive for tissue engineering applications due to their incredible versatility, but they can be limited in cartilage tissue engineering applications due to inadequate mechanical performance. In an effort to address this limitation, our team previously reported the drastic improvement in the mechanical performance of interpenetrating networks (IPNs) of poly(ethylene glycol) diacrylate (PEG-DA) and agarose relative to pure PEG-DA and agarose networks. The goal of the current study was specifically to determine the relative importance of PEG-DA concentration, agarose concentration, and PEG-DA molecular weight in controlling mechanical performance, swelling characteristics, and network parameters. IPNs consistently had compressive and shear moduli greater than the additive sum of either single network when compared to pure PEG-DA gels with a similar PEG-DA content. IPNs withstood a maximum stress of up to 4.0 MPa in unconfined compression, with increased PEG-DA molecular weight being the greatest contributing factor to improved failure properties. However, aside from failure properties, PEG-DA concentration was the most influential factor for the large majority of properties. Increasing the agarose and PEG-DA concentrations as well as the PEG-DA molecular weight of agarose/PEG-DA IPNs and pure PEG-DA gels improved moduli and maximum stresses by as much as an order of magnitude or greater compared to pure PEG-DA gels in our previous studies. Although the viability of encapsulated chondrocytes was not significantly affected by IPN formulation, glycosaminoglycan (GAG) content was significantly influenced, with a 12-fold increase over a three-week period in gels with a lower PEG-DA concentration. These results suggest that mechanical performance of IPNs may be tuned with partial but not complete independence from biological performance of encapsulated cells. © 2013 Elsevier Ltd. All rights reserved.
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NASA Technical Reports Server (NTRS)
Pater, Ruth H. (Inventor); Hansen, Marion G. (Inventor)
1997-01-01
In the process of the present invention, a non-polar, aprotic solvent is removed from an oligomer/polymer solution by freeze-drying in order to produce IPNs and semi-IPNs. By thermally quenching the solution to a solid in a short length of time, the size of the minor constituent-rich regions is greatly reduced as they are excluded along with the major constituent from the regions of crystallizing solvent. The use of this process sequence of controlling phase morphology provides IPNs and semi-IPNs with improved fracture toughness, microcracking resistance, and other physical-mechanical properties as compared to IPNs and semi-IPNs formed when the solvent is evaporated rather than sublimed.
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NASA Technical Reports Server (NTRS)
Pater, Ruth H. (Inventor); Hansen, Marion G. (Inventor)
1998-01-01
In the process of the present invention, a non-polar, aprotic solvent is removed from an oligomer/polymer solution by freeze-drying in order to produce IPNs and semi-IPNs. By thermally quenching the solution to a solid in a short length of time, the size of the minor constituent-rich regions is greatly reduced as they are excluded along with the major constituent from the regions of crystallizing solvent. The use of this process sequence of controlling phase morphology provides IPNs and semi-IPNs with improved fracture toughness, microcracking resistance, and other physical-mechanical properties as compared to IPNs and semi-IPNs formed when the solvent is evaporated rather than sublimed.
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Zhou, Dan; Yang, Liping; Yang, Runmiao; Song, Weihua; Peng, Shuhua; Wang, Yanmei
2009-11-15
A new matrix additive, poly (N,N-dimethylacrylamide)-functionalized gold nanoparticle (GNP-PDMA), was prepared by "grafting-to" approach, and then incorporated into quasi-interpenetrating network (quasi-IPN) composed of linear polyacrylamide (LPA, 3.3 MDa) and PDMA to form novel polymer/metal composite sieving matrix (quasi-IPN/GNP-PDMA) for DNA sequencing by capillary electrophoresis. Without complete optimization, quasi-IPN/GNP-PDMA yielded a readlength of 801 bases at 98% accuracy in about 64 min by using the ABI 310 Genetic Analyzer at 50 degrees C and 150 V/cm. Compared with previous quasi-IPN/GNPs, quasi-IPN/GNP-PDMA can further improve DNA sequencing performances. This is because the presence of GNP-PDMA can improve the compatibility of GNPs with the whole sequencing system, enhance the entanglement degree of networks, and increase the GNP concentration in system, which consequently lead to higher restriction and stability, higher apparent molecular weight (MW), and smaller pore size of the total sieving networks. Furthermore, the composite matrix was also compared with quasi-IPN containing higher-MW LPA and commercial POP-6. The results indicate that the composite matrix is a promising one for DNA sequencing to achieve full automation due to the separation provided with high resolution, speediness, excellent reproducibility, and easy loading in the presence of GNP-PDMA.
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Liu, Jun; Li, Qingshan; Zhuo, Yuguo; Hong, Wei; Lv, Wenfeng; Xing, Guangzhong
2014-06-01
P(U-MMA-ANI) interpenetrating polymer network (IPN) damping and absorbing material is successfully synthesized by PANI particles served as an absorbing agent with the microemulsion polymerization and P(U-MMA) foam IPN network structure for substrate materials with foaming way. P(U-MMA-ANI) IPN is characterized by the compression mechanical performance testing, TG-DSC, and DSC. The results verify that the P(U-MMA) IPN foam damping material has a good compressive strength and compaction cycle property, and the optimum content of PMMA was 40% (mass) with which the SEM graphs do not present the phase separation on the macro level between PMMA and PU, while the phase separation was observed on the micro level. The DTG curve indicates that because of the formation of P(U-MMA) IPN, the decomposition temperature of PMMA and the carbamate in PU increases, while that of the polyol segment in PU has almost no change. P(U-MMA-ANI) IPN foam damping and absorbing material is obtained by PANI particles served as absorbing agent in the form of filler, and PMMA in the form of micro area in substrate material. When the content of PANI was up to 2.0% (mass), the dissipation factor of composites increased, and with the increasing of frequency the dissipation factor increased in a straight line.
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NASA Technical Reports Server (NTRS)
Kouveliotou, C.
2012-01-01
Magnetars are magnetically powered rotating neutron stars with extreme magnetic fields (over 10^14 Gauss). They were discovered in the X- and gamma-rays where they predominantly emit their radiation. Very few sources (roughly 24) have been found since their discovery in 1987. NASA's Fermi Gamma-ray Space Telescope was launched June 11, 2009; since then the Fermi Gamma-ray Burst Monitor (GBM) recorded emission from several magnetar sources. In total, six new sources were discovered between 2008 and 2011, with a synergy between Swift, RXTE, Fermi and the Interplanetary Network (IPN). In my talk I will give a short history of magnetars and describe how this, once relatively esoteric field, has emerged as a link between several astrophysical areas including Gamma-Ray Bursts. Finally, I will describe the exciting new results of Fermi and Chandra in this field and the current status of our knowledge of the magnetar population properties and magnetic fields.
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Synthesis of wheat straw cellulose-g-poly (potassium acrylate)/PVA semi-IPNs superabsorbent resin.
Liu, Jia; Li, Qian; Su, Yuan; Yue, Qinyan; Gao, Baoyu; Wang, Rui
2013-04-15
To better use wheat straw and minimize its negative impact on environment, a novel semi-interpenetrating polymer networks (semi-IPNs) superabsorbent resin (SAR) composed of wheat straw cellulose-g-poly (potassium acrylate) (WSC-g-PKA) network and linear polyvinyl alcohol (PVA) was prepared by polymerization in the presence of a redox initiating system. The structure and morphology of semi-IPNs SAR were characterized by means of FTIR, SEM and TGA, which confirmed that WSC and PVA participated in the graft polymerization reaction with acrylic acid (AA). The factors that can influence the water absorption of the semi-IPNs SAR were investigated and optimized, including the weight ratios of AA to WSC and PVA to WSC, the content of initiator and crosslinker, neutralization degree (ND) of AA, reaction temperature and time. The semi-IPNs SAR prepared under optimized synthesis condition gave the best water absorption of 266.82 g/g in distilled water and 34.32 g/g in 0.9 wt% NaCl solution. Copyright © 2013 Elsevier Ltd. All rights reserved.
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Enhanced Multi-Modal Access to Planetary Exploration
NASA Technical Reports Server (NTRS)
Lamarra, Norm; Doyle, Richard; Wyatt, Jay
2003-01-01
Tomorrow's Interplanetary Network (IPN) will evolve from JPL's Deep-Space Network (DSN) and provide key capabilities to future investigators, such as simplified acquisition of higher-quality science at remote sites and enriched access to these sites. These capabilities could also be used to foster public interest, e.g., by making it possible for students to explore these environments personally, eventually perhaps interacting with a virtual world whose models could be populated by data obtained continuously from the IPN. Our paper looks at JPL's approach to making this evolution happen, starting from improved communications. Evolving space protocols (e.g., today's CCSDS proximity and file-transfer protocols) will provide the underpinning of such communications in the next decades, just as today's rich web was enabled by progress in Internet Protocols starting from the early 1970's (ARPAnet research). A key architectural thrust of this effort is to deploy persistent infrastructure incrementally, using a layered service model, where later higher-layer capabilities (such as adaptive science planning) are enabled by earlier lower-layer services (such as automated routing of object-based messages). In practice, there is also a mind shift needed from an engineering culture raised on point-to-point single-function communications (command uplink, telemetry downlink), to one in which assets are only indirectly accessed, via well-defined interfaces. We are aiming to foster a 'community of access' both among space assets and the humans who control them. This enables appropriate (perhaps eventually optimized) sharing of services and resources to the greater benefit of all participants. We envision such usage to be as automated in the future as using a cell phone is today - with all the steps in creating the real-time link being automated.
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Kleinbeck, Kyle R.; Bader, Rebecca A.; Kao, Weiyuan John
2013-01-01
In situ photopolymerized semi-interpenetrating networks (sIPNs) composed of poly(ethylene glycol) and gelatin are promising multifunctional matrices for a regenerative medicine approach to dermal wound treatment. In addition to previously demonstrated efficacy in critical defects, sIPNs also function as drug delivery matrices for compounds loaded as either soluble or covalently linked components. Simultaneous release of silver sulfadiazine and bupivacaine from the sIPN would provide multiple-hit management of dermal wounds that minimizes infection, and manages pain along with sIPN absorption of exudates and facilitation of epidermal regrowth. We characterized the release of soluble silver sulfadiazine and bupivacaine and compared it with an established release model. Efficacy of released silver sulfadiazine was confirmed in vitro on Staphylococcus aureus, methicillin resistant S. aureus, and Pseudomonas aeruginosa. Bupivacaine loaded without silver sulfadiazine showed incomplete release, whereas simultaneous loading with silver sulfadiazine facilitated 100% bupivacaine release. Silver sulfadiazine released at 98% without bupivacaine and 96% with bupivacaine. Silver sulfadiazine released onto bacterial cultures inhibited all three strains dose dependently. sIPNs effectively release bupivacaine and silver sulfadiazine while maintaining the antimicrobial activity of silver sulfadiazine. Drug loaded sIPNs have potential to improve wound management by providing multi-drug delivery along with an effective wound treatment. PMID:19060724
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NASA Astrophysics Data System (ADS)
Xiu, Kemao
Bacterial infection and biofilm formation cause serious medical, industrial, and environmental problems. In biomedical applications, bacterial contamination of medical devices often leads to infectious diseases accompanied with pain, suffer, and even death. Polyurethane (PU) is widely in biomedical applications due to its good mechanical properties and biocompatibility. However, its vulnerability to bacterial biofilm formation seriously limits its wider uses. Prior studies have shown that N-halamines could be incorporated into PU to achieve antimicrobial and biofilm-controlling effects through grafting, blending, and/or coating. To broaden the selection of modification methods in the development antimicrobial PU, this study synthesized polyurethane/polymeric N-halamine semi-interpenetrating polymer networks (semi-IPN). Polymerizable monomeric N-halamines were swollen into PU with initiators and crosslink agents. Post polymerization of the monomers led to the formation of semi-IPN with linear PU and N-halamine polymer networks. The semi-IPNs showed excellent antimicrobial and biofilm controlling ability towards both gram-positive and gram-negative bacteria. The effects of hydrophilicity, surface grafted N-halamine and structural characteristics of N-halamine on the antimicrobial behavior of the resulting semi-IPNs were also investigated.
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Maity, Jayabrata; Ray, Samit Kumar
2014-04-15
Semi and full interpenetrating polymer network (IPN) type hydrogels were prepared by free radical in situ polymerization of methacrylic acid in presence of chitosan using N,N'-methylene-bis-acrylamide (MBA) and glutaraldehyde (for full IPN) as crosslinker. Several semi and full IPN type hydrogels were prepared by varying initiator and crosslinker concentration and also monomer to chitosan mass ratio. These hydrogels were characterized and used for removal of methyl violet and congo red dye from water. Isotherms and kinetics of dye adsorption were also evaluated. Copyright © 2014 Elsevier Ltd. All rights reserved.
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Ingavle, Ganesh C.; Frei, Anthony W.; Gehrke, Stevin H.
2013-01-01
Interpenetrating network (IPN) hydrogels were recently introduced to the cartilage tissue engineering literature, with the approach of encapsulating cells in thermally gelling agarose that is then soaked in a poly(ethylene glycol) diacrylate (PEGDA) solution, which is then photopolymerized. These IPNs possess significantly enhanced mechanical performance desirable for cartilage regeneration, potentially allowing patients to return to weight-bearing activities quickly after surgical implantation. In an effort to improve cell viability and performance, inspiration was drawn from previous studies that have elicited positive chondrogenic responses to aggrecan, the proteoglycan largely responsible for the compressive stiffness of cartilage. Aggrecan was incorporated into the IPNs in conservative concentrations (40 μg/mL), and its effect was contrasted with the incorporation of chondroitin sulfate (CS), the primary glycosaminoglycan associated with aggrecan. Aggrecan was incorporated by physical entrapment within agarose and methacrylated CS was incorporated by copolymerization with PEGDA. The IPNs incorporating aggrecan or CS exhibited over 50% viability with encapsulated chondrocytes after 6 weeks. Both aggrecan and CS improved cell viability by 15.6% and 20%, respectively, relative to pure IPNs at 6 weeks culture time. In summary, we have introduced the novel approach of including a raw material from cartilage, namely aggrecan, to serve as a bioactive signal to cells encapsulated in IPN hydrogels for cartilage tissue engineering, which led to improved performance of encapsulated chondrocytes. PMID:23379843
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A green approach to prepare silver nanoparticles loaded gum acacia/poly(acrylate) hydrogels.
Bajpai, S K; Kumari, Mamta
2015-09-01
In this work, gum acacia (GA)/poly(sodium acrylate) semi-interpenetrating polymer networks (Semi-IPN) have been fabricated via free radical initiated aqueous polymerization of monomer sodium acrylate (SA) in the presence of dissolved Gum acacia (GA), using N,N'-methylenebisacrylamide (MB) as cross-linker and potassium persulphate (KPS) as initiator. The semi-IPNs, synthesized, were characterized by various techniques such as X-ray diffraction (XRD), thermo gravimetric analysis (TGA) and Fourier transform infrared (FTIR) spectroscopy. The dynamic water uptake behavior of semi-IPNs was investigated and the data were interpreted by various kinetic models. The equilibrium swelling data were used to evaluate various network parameters. The semi-IPNs were used as template for the in situ preparation of silver nanoparticles using extract of Syzygium aromaticum (clove). The formation of silver nanoparticles was confirmed by surface plasmon resonance (SPR), XRD and transmission electron microscopy (TEM). Finally, the antibacterial activity of GA/poly(SA)/silver nanocomposites was tested against E. coli. Copyright © 2015 Elsevier B.V. All rights reserved.
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Plastic deformation mechanisms in polyimide resins and their semi-interpenetrating networks
NASA Technical Reports Server (NTRS)
Jang, Bor Z.
1990-01-01
High-performance thermoset resins and composites are critical to the future growth of space, aircraft, and defense industries in the USA. However, the processing-structure-property relationships in these materials remain poorly understood. In the present ASEE/NASA Summer Research Program, the plastic deformation modes and toughening mechanisms in single-phase and multiphase thermoset resins were investigated. Both thermoplastic and thermoset polyimide resins and their interpenetrating networks (IPNs and semi-IPNs) were included. The fundamental tendency to undergo strain localization (crazing and shear banding) as opposed to a more diffuse (or homogeneous) deformation in these polymers were evaluated. Other possible toughening mechanisms in multiphase thermoset resins were also examined. The topological features of network chain configuration/conformation and the multiplicity of phase morphology in INPs and semi-IPNs provide unprecedented opportunities for studying the toughening mechanisms in multiphase thermoset polymers and their fiber composites.
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3D Printed Silicone-Hydrogel Scaffold with Enhanced Physicochemical Properties.
Mohanty, Soumyaranjan; Alm, Martin; Hemmingsen, Mette; Dolatshahi-Pirouz, Alireza; Trifol, Jon; Thomsen, Peter; Dufva, Martin; Wolff, Anders; Emnéus, Jenny
2016-04-11
Scaffolds with multiple functionalities have attracted widespread attention in the field of tissue engineering due to their ability to control cell behavior through various cues, including mechanical, chemical, and electrical. Fabrication of such scaffolds from clinically approved materials is currently a huge challenge. The goal of this work was to fabricate a tissue engineering scaffold from clinically approved materials with the capability of delivering biomolecules and direct cell fate. We have used a simple 3D printing approach, that combines polymer casting with supercritical fluid technology to produce 3D interpenetrating polymer network (IPN) scaffold of silicone-poly(2-hydroxyethyl methacrylate)-co-poly(ethylene glycol) methyl ether acrylate (pHEMA-co-PEGMEA). The pHEMA-co-PEGMEA IPN materials were employed to support growth of human mesenchymal stem cells (hMSC), resulting in high cell viability and metabolic activity over a 3 weeks period. In addition, the IPN scaffolds support 3D tissue formation inside the porous scaffold with well spread cell morphology on the surface of the scaffold. As a proof of concept, sustained doxycycline (DOX) release from pHEMA-co-PEGMEA IPN was demonstrated and the biological activity of released drug from IPN was confirmed using a DOX regulated green fluorescent reporter (GFP) gene expression assay with HeLa cells. Given its unique mechanical and drug releasing characteristics, IPN scaffolds may be used for directing stem cell differentiation by releasing various chemicals from its hydrogel network.
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Lu, Jingqiong; Li, Yinhui; Hu, Deng; Chen, Xiaoling; Liu, Yongmei; Wang, Liping; Zhao, Yansheng
2015-01-01
Modified poly(aspartic acid)/poly(vinyl alcohol) interpenetrating polymer network (KPAsp/PVA IPN) hydrogel for drug controlled release was synthesized by a simple one-step method in aqueous system using poly(aspartic acid) grafting 3-aminopropyltriethoxysilane (KH-550) and poly(vinyl alcohol) (PVA) as materials. The hydrogel surface morphology and composition were characterized by Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM). The thermal stability was analyzed by thermogravimetric analysis (TGA). The swelling properties and pH, temperature, and salt sensitivities of KPAsp, KPAsp/PVA semi-interpenetrating polymer network (semi-IPN), and KPAsp/PVA IPN hydrogels were also investigated. All of the three hydrogels showed ampholytic pH-responsive properties, and swelling behavior was also extremely sensitive to the temperature, ionic strength, and cationic species. Finally, the drug controlled release properties of the three hydrogels were evaluated and results indicated that three hydrogels could control drug release by external surroundings stimuli. The drug controlled release properties of KPAsp/PVA IPN hydrogel are the most outstanding, and the correlative measured release profiles of salicylic acid at 37°C were 32.6 wt% at pH = 1.2 (simulated gastric fluid) and 62.5 wt% at pH = 7.4 (simulated intestinal fluid), respectively. These results indicated that KPAsp/PVA IPN hydrogels are a promising carrier system for controlled drug delivery.
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NASA Astrophysics Data System (ADS)
Cho, Eunhae; Won, Jongok
2016-12-01
Novel composite membranes of a semi-interpenetrating network (semi-IPN) coated on the surfaces of a porous Celgard 2400 support are prepared and investigate for application in a non-aqueous redox flow battery (RFB). A natural polymer, urushi, is used for the matrix because of its high mechanical robustness, and poly(diallyldimethylammonium chloride) (PDDA) provides anionic exchange sites. The PDDA/urushi (P/U) semi-IPN film is prepared by the photo polymerization of urushiol in the presence of PDDA. The thin layer composed of the P/U semi-IPN on the porous support provides selectivity while maintaining the ion conductivity. The coulombic and energy efficiencies increase with increasing amounts of PDDA in the P/U semi-IPN layer, and the values reach 69.5% and 42.5%, respectively, for the one containing 40 wt% of PDDA. These values are substantially higher than those of the Neosepta AHA membrane and the Celgard membrane, indicating that the selective layer reduces the crossover of the redox active species through the membrane. This result implies that the formation of composite membranes using semi-IPN selective layers on the dimensionally stable porous membrane enable the successful use of a non-aqueous RFB for future energy storage systems.
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Fabrication of chitosan/polyacrylonitrile blend and semi-IPN hydrogel with epichlorohydrin
DOE Office of Scientific and Technical Information (OSTI.GOV)
Aijaz, Muhammad Omer; Haider, Sajjad, E-mail: shaider@ksu.edu.sa; Al Mubddel, Fahad S.
2015-05-22
The present study is focused on the preparation of chitosan (CS)/polyacrylonitrile (PAN) blend and semi-interpenetrating polymer network (sIPN). Blend CS/PAN hydrogel films (HFs) were prepared by solution blending and casting technique. CS in the blend was crosslinked with epichlorohydrin (ECH) to prepare sIPN. The developed CS/PAN blend and sIPN hydrogels were characterized with Field Emission Scanning Electron Microscopy (FE-SEM), Fourier transform infrared spectroscopy (FTIR), Thermagravimetric analysis (TGA), and Differential Scanning Calorimeter (DSC). The result showed good miscibility between CS and PAN and crosslinking of CS in the blend. The swelling of the different blended and sIPN hydrogels samples were examinedmore » at room temperature (T{sub r}). Blend (C80/P20) sample showed highest swelling (∼2400%) and fair degree of stability (∼28% until 96 h), whereas sIPN hydrogel exhibited relatively low degree of swelling (∼244%) and high degree of aqueous (∼85 % until 96 h), and thermal (onset temperature 304°C) stabilities.« less
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Interpenetrating polymer networks from acetylene terminated materials
NASA Technical Reports Server (NTRS)
Connell, J. W.; Hergenrother, P. M.
1989-01-01
As part of a program to develop high temperature/high performance structural resins for aerospace applications, the chemistry and properties of a novel class of interpenetrating polymer networks (IPNs) were investigated. These IPNs consist of a simple diacetylenic compound (aspartimide) blended with an acetylene terminated arylene ether oligomer. Various compositional blends were prepared and thermally cured to evaluate the effect of crosslink density on resin properties. The cured IPNs exhibited glass transition temperatures ranging from 197 to 254 C depending upon the composition and cure temperature. The solvent resistance, fracture toughness and coefficient of thermal expansion of the cured blends were related to the crosslink density. Isothermal aging of neat resin moldings, adhesive and composite specimens showed a postcure effect which resulted in improved elevated temperature properties. The chemistry, physical and mechanical properties of these materials will be discussed.
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Bidault, Laurent; Deneufchatel, Marie; Vancaeyzeele, Cédric; Fichet, Odile; Larreta-Garde, Véronique
2013-11-11
A fibrin hydrogel at physiological concentration (5 mg/mL) was associated with polyvinyl alcohol (PVA) inside an interpenetrating polymer networks (IPN) architecture. Previously, PVA has been modified with methacrylate functions in order to cross-link it by free-radical polymerization. The fibrin network was synthesized by the enzymatic hydrolysis of fibrinogen by thrombin. The resulting self-supported materials simultaneously exhibit the properties of the fibrin hydrogel and those of the synthetic polymer network. Their storage modulus is 50-fold higher than that of the fibrin hydrogel and they are completely rehydratable. These materials are noncytotoxic toward human fibroblast and the fibrin present on the surface of PVAm-based IPNs favors cell development.
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Boppana, Rashmi; Krishna Mohan, G; Nayak, Usha; Mutalik, Srinivas; Sa, Biswanath; Kulkarni, Raghavendra V
2015-04-01
This article reports the development of pH-sensitive interpenetrating polymer network (IPN) microbeads using polyacrylamide-grafted-gum ghatti (PAAm-g-GG) and sodium alginate (SA) for gastro-protective controlled delivery of ketoprofen. We have synthesized PAAm-grafted-GG copolymer under microwave irradiation using cerric ammonium nitrate as reaction initiator; further, the PAAm-g-GG was converted to pH-sensitive copolymer through alkaline hydrolysis. Sophisticated instrumentation techniques were used to characterize PAAm-g-GG. The IPN microbeads of PAAm-g-GG and SA, pre-loaded with ketoprofen were prepared by dual crosslinking using Ca(2+) ions and glutaraldehyde (GA). The IPN microbeads demonstrated excellent pH-sensitive behavior as noted in the pulsatile swelling test and scanning electron microscopy. IPN microbeads also showed larger amount of drug release in buffer solution of pH 7.4 as compared to drug release in solution of pH 1.2. The in vivo pharmacokinetic, pharmacodynamic and stomach histopathology studies conducted on wistar rats confirmed the pH-sensitive controlled release of ketoprofen; IPN microbeads retarded the drug release in stomach resulting in reduced adverse effects of ketoprofen. Copyright © 2015 Elsevier B.V. All rights reserved.
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High-Performance, Semi-Interpenetrating Polymer Network
NASA Technical Reports Server (NTRS)
Pater, Ruth H.; Lowther, Sharon E.; Smith, Janice Y.; Cannon, Michelle S.; Whitehead, Fred M.; Ely, Robert M.
1992-01-01
High-performance polymer made by new synthesis in which one or more easy-to-process, but brittle, thermosetting polyimides combined with one or more tough, but difficult-to-process, linear thermoplastics to yield semi-interpenetrating polymer network (semi-IPN) having combination of easy processability and high tolerance to damage. Two commercially available resins combined to form tough, semi-IPN called "LaRC-RP49." Displays improvements in toughness and resistance to microcracking. LaRC-RP49 has potential as high-temperature matrix resin, adhesive, and molding resin. Useful in aerospace, automotive, and electronic industries.
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Semi-2-interpenetrating polymer networks of high temperature systems
NASA Technical Reports Server (NTRS)
Hanky, A. O.; St. Clair, T. L.
1985-01-01
A semi-interpenetrating (semi-IPN) polymer system of the semi-2-IPN type is described in which a polymer of acetylene-terminated imidesulfone (ATPISO2) is cross linked in the presence of polyimidesulfone (PISO2). Six different formulations obtained by mixing of either ATPISO2-1n or ATPISO2-3n with PISO2 in three different proportions were characterized in terms of glass transition temperature, thermooxidative stability, inherent viscosity, and dynamic mechanical properties. Adhesive (lap shear) strength was tested at elevated temperatures on aged samples of adhesive scrim cloth prepared from each resin. Woven graphite (Celion 1000)/polyimide composites were tested for flexural strength, flexural modulus, and shear strength. The network polymers have properties intermediate between those of the component polymers alone, have greatly improved processability over either polyimide, and are able to form good adhesive bonds and composites, making the semi-2-IPN systems superior materials for aerospace structures.
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Freeze drying for morphological control of inter-penetrating polymer networks
NASA Technical Reports Server (NTRS)
Hansen, Marion G.; Pater, Ruth H.
1990-01-01
The intrinsic brittleness of BMI resins can be reduced through the creation of an interpenetrating network (IPN) of BMI with a reactive-encapped thermoplastic, such as the presently considered polyimidesulfone, PISO2. The PISO2 and BMI were dissolved in a common solvent, which was then removed from the constituents by freeze drying; in an alternative method, an IPN was formed through dissolution of the constituent in a common solvent with either high or low melting point, followed by evaporative removal of the solvent. The effectiveness of the freeze-drying approach for morphological control is evaluated.
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Upadhyay, Mansi; Adena, Sandeep Kumar Reddy; Vardhan, Harsh; Pandey, Sureshwar; Mishra, Brahmeshwar
2018-03-01
The objective of the study was to develop interpenetrating polymeric network (IPN) of capecitabine (CAP) using natural polymers locust bean gum (LBG) and sodium alginate (NaAlg). The IPN microbeads were optimized by Box-Behnken Design (BBD) to provide anticipated particle size with good drug entrapment efficiency. The comparative dissolution profile of IPN microbeads of CAP with the marketed preparation proved an excellent sustained drug delivery vehicle. Ionotropic gelation method utilizing metal ion calcium (Ca 2+ ) as a cross-linker was used to prepare IPN microbeads. The optimization study was done by response surface methodology based Box-Behnken Design. The effect of the factors on the responses of optimized batch was exhibited through response surface and contour plots. The optimized batch was analyzed for particle size, % drug entrapment, pharmacokinetic study, in vitro drug release study and further characterized by FTIR, XRD, and SEM. To study the water uptake capacity and hydrodynamic activity of the polymers, swelling studies and viscosity measurement were performed, respectively. The particle size and % drug entrapment of the optimized batch was 494.37 ± 1.4 µm and 81.39 ± 2.9%, respectively, closer to the value predicted by Minitab 17 software. The in vitro drug release study showed sustained release of 92% for 12 h and followed anomalous drug release pattern. The derived pharmacokinetic parameters of optimized batch showed improved results than pure CAP. Thus, the formed IPN microbeads of CAP proved to be an effective extended drug delivery vehicle for the water soluble antineoplastic drug.
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Kim, Ju-Myung; Park, Jang-Hoon; Lee, Chang Kee; Lee, Sang-Young
2014-04-08
As a promising power source to boost up advent of next-generation ubiquitous era, high-energy density lithium-ion batteries with reliable electrochemical properties are urgently requested. Development of the advanced lithium ion-batteries, however, is staggering with thorny problems of performance deterioration and safety failures. This formidable challenge is highly concerned with electrochemical/thermal instability at electrode material-liquid electrolyte interface, in addition to structural/chemical deficiency of major cell components. Herein, as a new concept of surface engineering to address the abovementioned interfacial issue, multifunctional conformal nanoencapsulating layer based on semi-interpenetrating polymer network (semi-IPN) is presented. This unusual semi-IPN nanoencapsulating layer is composed of thermally-cured polyimide (PI) and polyvinyl pyrrolidone (PVP) bearing Lewis basic site. Owing to the combined effects of morphological uniqueness and chemical functionality (scavenging hydrofluoric acid that poses as a critical threat to trigger unwanted side reactions), the PI/PVP semi-IPN nanoencapsulated-cathode materials enable significant improvement in electrochemical performance and thermal stability of lithium-ion batteries.
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NASA Astrophysics Data System (ADS)
Kim, Ju-Myung; Park, Jang-Hoon; Lee, Chang Kee; Lee, Sang-Young
2014-04-01
As a promising power source to boost up advent of next-generation ubiquitous era, high-energy density lithium-ion batteries with reliable electrochemical properties are urgently requested. Development of the advanced lithium ion-batteries, however, is staggering with thorny problems of performance deterioration and safety failures. This formidable challenge is highly concerned with electrochemical/thermal instability at electrode material-liquid electrolyte interface, in addition to structural/chemical deficiency of major cell components. Herein, as a new concept of surface engineering to address the abovementioned interfacial issue, multifunctional conformal nanoencapsulating layer based on semi-interpenetrating polymer network (semi-IPN) is presented. This unusual semi-IPN nanoencapsulating layer is composed of thermally-cured polyimide (PI) and polyvinyl pyrrolidone (PVP) bearing Lewis basic site. Owing to the combined effects of morphological uniqueness and chemical functionality (scavenging hydrofluoric acid that poses as a critical threat to trigger unwanted side reactions), the PI/PVP semi-IPN nanoencapsulated-cathode materials enable significant improvement in electrochemical performance and thermal stability of lithium-ion batteries.
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Kim, Ju-Myung; Park, Jang-Hoon; Lee, Chang Kee; Lee, Sang-Young
2014-01-01
As a promising power source to boost up advent of next-generation ubiquitous era, high-energy density lithium-ion batteries with reliable electrochemical properties are urgently requested. Development of the advanced lithium ion-batteries, however, is staggering with thorny problems of performance deterioration and safety failures. This formidable challenge is highly concerned with electrochemical/thermal instability at electrode material-liquid electrolyte interface, in addition to structural/chemical deficiency of major cell components. Herein, as a new concept of surface engineering to address the abovementioned interfacial issue, multifunctional conformal nanoencapsulating layer based on semi-interpenetrating polymer network (semi-IPN) is presented. This unusual semi-IPN nanoencapsulating layer is composed of thermally-cured polyimide (PI) and polyvinyl pyrrolidone (PVP) bearing Lewis basic site. Owing to the combined effects of morphological uniqueness and chemical functionality (scavenging hydrofluoric acid that poses as a critical threat to trigger unwanted side reactions), the PI/PVP semi-IPN nanoencapsulated-cathode materials enable significant improvement in electrochemical performance and thermal stability of lithium-ion batteries. PMID:24710575
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Semi-Interpenetrating Polymer Networks for Enhanced Supercapacitor Electrodes.
Fong, Kara D; Wang, Tiesheng; Kim, Hyun-Kyung; Kumar, R Vasant; Smoukov, Stoyan K
2017-09-08
Conducting polymers show great promise as supercapacitor materials due to their high theoretical specific capacitance, low cost, toughness, and flexibility. Poor ion mobility, however, can render active material more than a few tens of nanometers from the surface inaccessible for charge storage, limiting performance. Here, we use semi-interpenetrating networks (sIPNs) of a pseudocapacitive polymer in an ionically conductive polymer matrix to decrease ion diffusion length scales and make virtually all of the active material accessible for charge storage. Our freestanding poly(3,4-ethylenedioxythiophene)/poly(ethylene oxide) (PEDOT/PEO) sIPN films yield simultaneous improvements in three crucial elements of supercapacitor performance: specific capacitance (182 F/g, a 70% increase over that of neat PEDOT), cycling stability (97.5% capacitance retention after 3000 cycles), and flexibility (the electrodes bend to a <200 μm radius of curvature without breaking). Our simple and controllable sIPN fabrication process presents a framework to develop a range of polymer-based interpenetrated materials for high-performance energy storage technologies.
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Kulkarni, Raghavendra V; Patel, Foram S; Nanjappaiah, H M; Naikawadi, Akram A
2014-08-01
Interpenetrated polymer network (IPN) microparticles of sterculia gum and sodium alginate loaded with repaglinide were developed by ionic gelation and emulsion crosslinking method. The drug entrapment efficiency was as high as 91%. FTIR and TG analyses confirmed the crosslinking and IPN formation. Microparticles have demonstrated the drug release up to 24h depending upon type of crosslinking agents; the glutaraldehyde treatment of ionically crosslinked microparticles has resulted in decreased drug release rate. The in-vivo anti-diabetic activity performed on streptozotocin induced diabetic rats indicated that the pristine repaglinide has shown maximum percentage reduction of elevated blood glucose within 3h and then the percentage reduction in blood glucose was decreased. In the case of rats treated with KA8 IPN microparticles, percentage reduction of elevated glucose was slow as compared to pristine drug within 3h, but it was gradually increased to 81.27% up to 24h. Copyright © 2014 Elsevier B.V. All rights reserved.
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NASA Technical Reports Server (NTRS)
Singh, Jag J.; Pater, Ruth H.; Eftekhari, Abe
1996-01-01
Thermoset and thermoplastic polyimides have complementary physical and mechanical properties. Whereas thermoset polyimides are brittle and generally easier to process, thermoplastic polyimides are tough but harder to process. A combination of these two types of polyimides may help produce polymers more suitable for aerospace applications. Semi-Interpenetrating Polymer Networks (S-IPN) of thermoset LaRC(TM)-RP46 and thermoplastic LaRC(TM)-IA polyimides were prepared in weight percent ratios ranging from 100:0 to 0:100. Positron lifetime measurements were made in these samples to correlate their free volume features with physical and mechanical properties. As expected, positronium atoms are not formed in these samples. The second lifetime component has been used to infer the positron trap dimensions. The 'free volume' goes through a minimum at a ratio of about 50:50, and this suggests that S-IPN samples are not merely solid solutions of the two polymers. These data and related structural properties of the S-IPN samples are discussed.
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Structure and properties of semi-interpenetrating network hydrogel based on starch.
Zhu, Baodong; Ma, Dongzhuo; Wang, Jian; Zhang, Shuang
2015-11-20
Starch-g-P(acrylic acid-co-acrylamide)/PVA semi-interpenetrating network (semi-IPN) hydrogels were prepared by aqueous solution polymerization method. Starch grafting copolymerization reaction, semi-IPN structure and crystal morphology were characterized by Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD). The PVA in the form of partial crystallization distributing in the gel matrix uniformly were observed by Field emission scanning electron microscope (FESEM). The space network structure, finer microstructure and pore size in the interior of hydrogel were presented by biomicroscope. The results demonstrated that absorption ratio of water and salt generated different degree changes with the effect of PVA. In addition, the mechanical strength of hydrogel was improved. Copyright © 2015 Elsevier Ltd. All rights reserved.
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Superporous polyacrylate/chitosan IPN hydrogels for protein delivery.
Gümüşderelioğlu, Menemşe; Erce, Deniz; Demirtaş, T Tolga
2011-11-01
In this study, poly(acrylamide), poly(AAm), and poly(acrylamide-co-acrylic acid), poly(AAm-co-AA) superporous hydrogels (SPHs) were synthesized by radical polymerization in the presence of gas blowing agent, sodium bicarbonate. In addition, ionically crosslinked chitosan (CH) superporous hydrogels were synthesized to form interpenetrating superporous hydrogels, i.e. poly(AAm)-CH and poly(AAm-co-AA)-CH SPH-IPNs. The hydrogels have a structure of interconnected pores with pore sizes of approximately 100-150 μm. Although the extent of swelling increased when AA were incorporated to the poly(AAm) structure, the time to reach the equilibrium swelling (~30 s) was not affected so much. In the presence of chitosan network mechanical properties significantly improved when compared with SPHs, however, equilibrium swelling time (~30 min) was prolonged significantly as due to the lower porosities and pore sizes of SPH-IPNs than that of SPHs. Model protein bovine serum albumin (BSA) was loaded into SPHs and SPH-IPNs by solvent sorption in very short time (<1 h) and very high capacities (~30-300 mg BSA/g dry gel) when compared to conventional hydrogels. BSA release profiles from SPHs and SPH-IPNs were characterized by an initial burst of protein during the first 20 min followed by a completed release within 1 h. However, total releasable amount of BSA from SPH-IPNs was lower than that of SPHs as due to the electrostatic interactions between chitosan and BSA.
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DOE Office of Scientific and Technical Information (OSTI.GOV)
Ray, A.K.
1995-12-01
Semi-interpenetrating (S-IPN) network polyimids were made from different proportions of LaRC RP46 (a thermosetpolyimid) and LaRC BDTA-ODA (a thermoplastic polyimid). The ultimate goal of this networking is to improve the mechanical properties of the thermoset polyimid. Positron lifetime study was made to calculate lifetime based on second component of the life time spectra and the free volume & microvoid size. All these properties tend to decrease steadily with increasing thermoset content except at the 50 percent thermoset level where these properties show sudden drop. This result contradicts with the initial expectation that the blend properties should change gradually if itmore » were a solid solution of thermoset (TSP) and thermoplastic (TPP) components. Thermal analyses (TMA, DSC, DMA & TGA) were run to complement the positron life time studies. The TMA and DSC studies confirm the contradiction mentioned above. Further experimentation with S-IPN polymers made at TSP/TTP content around 50/50 level are being conducted to explain this anomaly. Scanning electron microscope study of the S-IPN polyimid samples is under way in order to detect morphological differences which might help explain the phenomenon mentioned above.« less
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Liu, Jia; Li, Qian; Su, Yuan; Yue, Qinyan; Gao, Baoyu
2014-07-17
A novel wheat straw cellulose-g-poly(potassium acrylate)/polyvinyl alcohol (WSC-g-PKA/PVA) semi-interpenetrating polymer networks (semi-IPNs) hydrogel was prepared by polymerizing wheat straw and an aqueous solution of acrylic acid (AA), and further semi-interpenetrating with PVA occurred during the chemosynthesis. The swelling and deswelling properties of WSC-g-PKA/PVA semi-IPNs hydrogel and WSC-g-PKA hydrogel were studied and compared in various pH solutions, salt solutions, temperatures, particle sizes and ionic strength. The results indicated that both hydrogels had the largest swelling capacity at pH=6, and the effect of ions on the swelling of hydrogels was in the order: Na(+)>K(+)>Mg(2+)>Ca(2+). The Schott's pseudo second order model can be effectively used to evaluate swelling kinetics of hydrogels. Moreover, the semi-IPNs hydrogel had improved swelling-deswelling properties compared with that of WSC-g-PKA hydrogel. Copyright © 2014 Elsevier Ltd. All rights reserved.
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Su, Yuan; Liu, Jia; Yue, Qinyan; Li, Qian; Gao, Baoyu
2014-01-01
A new feather protein-grafted poly(potassium acrylate)/polyvinyl alcohol (FP-g-PKA/PVA) semi-interpenetrating polymer networks (semi-IPNs) hydrogel was produced through graft copolymerization with FP as a basic macromolecular skeletal material, acrylic acid as a monomer and PVA as a semi-IPNs polymer. The adsorption of ammonium and phosphate ions from aqueous solution using the new hydrogel as N and P controlled-release fertilizer with water-retention capacity was studied. The effects of pH value, concentration, contact time and ion strength on NH4+ and PO3-4 removal by FP-g-PKA/PVA semi-IPNs hydrogel were investigated using batch adsorption experiments. The results indicated that the hydrogel had high adsorption capacities and fast adsorption rates for NH4+ and PO3-4 in wide pH levels ranging from 4.0 to 9.0. Kinetic analysis presented that both NH4+ and PO3-4 removal were closely fitted with the pseudo-second-order model. Furthermore, the adsorption isotherms of hydrogel were best represented by the Freundlich model. The adsorption-desorption experimental results showed the sustainable stability of FP-g-PKA/PVA semi-IPNs hydrogel for NH4+ and PO3-4 removal. Overall, FP-g-PKA/PVA could be considered as an efficient material for the removal and recovery of nitrogen and phosphorus with the agronomic reuse as a fertilizer.
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Khatami, Leila; Khodagholi, Fariba; Motamedi, Fereshteh
2018-04-16
The Interpedundular nucleus (IPN) is a small midbrain structure located deeply between the two cerebral peduncles. The strategic placement of this nucleus makes it a possible relay between structures involved in the modulation of hippocampal theta rhythm activity. In this study we aimed to investigate how reversible inactivation of IPN could affect the acquisition, consolidation and retrieval phases of memory in passive avoidance (PA) and Morris water maze (MWM) tasks. To support our data, molecular studies were performed in order to detect possible changes in the expression of proteins related to learning and memory in the hippocampus. To address this issue rats' IPN was reversibly inactivated by microinjection of lidocaine hydrochloride (4%). After the behavioral studies, the phosphorylation of CREB and P70, and c-fos expression levels in the hippocampus were determined using western blotting and immunohistochemistry respectively. Our results in the PA and MWM tasks showed that IPN reversible inactivation could impair immediate post training consolidation and retrieval while it had no effect on the acquisition phase. In addition, there was a deficit in the retention of the MWM working memory. Our data showed the ratio of pCREB/CREB, pP70/P70 and c-fos expression in the hippocampus significantly decreased after IPN reversible inactivation. Collectively, the results show that behaviorally defined changes could be due to what happens molecularly in the hippocampus after IPN reversible inactivation. It is concluded that IPN not only makes part of a network involved in the modulation of hippocampal theta rhythm activity, but also is actively engaged in hippocampal memory formation. Copyright © 2018 Elsevier B.V. All rights reserved.
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Rwei, Syang-Peng; Tuan, Huynh Nguyen Anh; Chiang, Whe-Yi; Way, Tun-Fun
2018-04-28
A series of semi-interpenetrating polymer network (semi-IPN) hydrogels were synthesized and investigated in this study. Linear copolymer poly( N -isopropylacrylamide-co-itaconamic acid) p(NIPAM-co-IAM), which is formed by copolymerization of N -isopropylacrylamide (NIPAM) and itaconamic acid (IAM, 4-amino-2-ethylene-4-oxobutanoic acid), was introduced into a solution of NIPAM to form a series of pH and thermo dual-responsive p(NIPAM-co-IAM)/pNIPAM semi-IPN hydrogels by free radical polymerization. The structural, morphological, chemical, and physical properties of the linear copolymer and semi-IPN hydrogels were investigated. The semi-IPN hydrogel showed high thermal stability according to thermal gravimetric analyzer (TGA). Scanning electronic microscopy (SEM) images showed that the pore size was in the range of 119~297 µm and could be controlled by the addition ratio of the linear copolymer in the semi-IPN structure. The addition of linear copolymer increased the fracture strain from 57.5 ± 2.9% to 91.1 ± 4.9% depending on the added amount, while the compressive modulus decreased as the addition increased. Moreover, the pH and thermo dual-responsive properties were investigated using differential scanning calorimetry (DSC) and monitoring the swelling behavior of the hydrogels. In deionized (DI) water, the equilibrium swelling ratio of the hydrogels decreased as the temperature increased from 20 °C to 50 °C, while it varied in various pH buffer solutions. In addition, the swelling and deswelling rates of the hydrogels also significantly increased. The results indicate that the novel pH-thermo dual-responsive semi-IPN hydrogels were synthesized successfully and may be a potential material for biomedical, drug delivery, or absorption application.
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Synthesis, kinetics and characterizations of polyimide based semi-IPN systems
DOE Office of Scientific and Technical Information (OSTI.GOV)
Tai, H.J.
1992-01-01
The PMR-15 polyimide is the leading matrix resin for high performance composites for use in high temperature and thermo-oxidative environments. This resin has superior mechanical properties, good processability and a high working temperature at around 300[degrees]C. It has the disadvantages of being brittle and high susceptibility to microcracking from thermal cycling that limit its widespread application. To improve the fracture toughness, a thermoplastic polyimide, LARC-TPI, and a thermoplastic poly (amide imide), Amoco AI-10, were added individually to PMR-15 resin to form sequential semi-interpenetrating polymer networks (semi-2-IPNs). the kinetics of imidization of LARC-TPI were studied using TGA technique. Both the solventmore » and the glass transition temperature were found to greatly affect the imidization kinetics. The kinetics could be well modeled by a two-step reaction: the first step being a second order reaction followed by a first order diffusion controlled reaction as the second step. The curing of PMR-15 and PMR-15/LARC-TPI semi-IPN was investigated by DSC. A first order reaction kinetics could describe the curing process adequately, implying that the reverse Diels-Alder reaction of the Norbornene end group was the rate controlling step. The glass transition temperature played an important role. The higher the fraction LARC-TPI, the higher the glass transition temperature of the semi-IPN prepolymer, and the slower the cure reaction. From a knowledge of kinetics, the molding cycle of PMR-15 and PMR-15/LARC-TPI semi-IPNs were determined. Both PMR-15/LARC-TPI and PMR-15/AI-10 semi-IPN systems exhibited much higher fracture toughness than PMR-15, but at the compromise of a reduction in the glass transition temperature. A single glass transition temperature for each semi-IPN was observed but there was presence of special intermolecular interaction. Tg measurements and IR spectroscopy indicated that both semi-IPN systems were compatible polymer pairs.« less
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NASA Technical Reports Server (NTRS)
Singh, Jag J.; Pater, Ruth H.; Eftekhari, Abe
1998-01-01
Thermoset and thermoplastic polyimides have complementary physical/mechanical properties. Whereas thermoset polyimides are brittle and generally easier to process, thermoplastic polyimides are tough but harder to process. It is expected that a combination of these two types of polyimides may help produce polymers more suitable for aerospace applications. Semi-Interpenetrating Polymer Networks (S-IPNs) of thermoset LaRC(Trademark)-RP46 and thermoplastic LARC(Trademark)-IA polyimides were prepared in weight percent ratios ranging from 100:0 to 0: 100. Positron lifetime measurements were made in these samples to correlate their free volume features with physical/mechanical properties. As expected, positronium atoms are not formed in these samples. The second life time component has been used to infer the positron trap dimensions. The "free volume" goes through a minimum at about 50:50 ratio, suggesting that S-IPN samples are not merely solid solutions of the two polymers. These data and related structural properties of the S-IPN samples have been discussed in this paper.
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A tough performance simultaneous semi-interpenetrating polymer network
NASA Technical Reports Server (NTRS)
Pater, Ruth H. (Inventor)
1989-01-01
A semi-interpenetrating polyimide (semi-IPN) network and methods for making and using the same are disclosed. The semi-IPN system comprises a high performance thermosetting polyimide having an acetylene-terminated group acting as a crosslinking site and a high performance linear thermoplastic polyimide. The polymer is made by combining low viscosity precursors and low molecular weight polymers of the thermosetting and thermoplastic polyimides and allowing them to react in the immediate presence of each other to form a simultaneous semi-interpenetrating polyimide network. Provided is a high temperature system having significantly improved processability and damage tolerance while maintaining excellent thermo-oxidative stability, mechanical properties and resistance to humidity, when compared with the commercial high temperature resin, Thermid 600. This material is particularly adapted for use as a molding, adhesive and advanced composite matrix for aerospace structural and electronic applications.
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Fermi/GBM Results of Magnetars
NASA Technical Reports Server (NTRS)
Kouveliotou, chryssa
2011-01-01
Magnetars are magnetically powered rotating neutron stars with extreme magnetic fields (over 10(exp 14) Gauss). They were discovered in the X- and gamma-rays where they predominantly emit their radiation. Very few sources (roughly 18) have been found since their discovery in 1987. NASA's Fermi Gamma-ray Space Telescope was launched June 11,2009; since then the Fermi Gamma-ray Burst Monitor (GBM) recorded emission from four magnetar sources. Two of these were brand new sources, SGR J0501 +4516, discovered with Swift and extensively monitored with Swift and GBM, SGR J0418+5729, discovered with GBM and the Interplanetary Network (IPN). A third was SGR Jl550-5418, a source originally classified as an Anomalous X-ray Pulsar (AXP IEI547.0-5408), but exhibiting a very prolific outburst with over 400 events recorded in January 2009. In my talk I will give a short history of magnetars and describe how this, once relatively esoteric field, has emerged as a link between several astrophysical areas including Gamma-Ray Bursts. Finally, I will describe the exciting new results of Fermi in this field and the current status of our knowledge of the magnetar population properties and magnetic fields.
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NASA Technical Reports Server (NTRS)
Kouveliotou, Chryssa
2011-01-01
Magnetars are magnetically powered rotating neutron stars with extreme magnetic fields (over 10(exp 14) Gauss). They were discovered in the X- and gamma-rays where they predominantly emit their radiation. Very few sources (roughly 18) have been found since their discovery in 1987. NASA's Fermi Gamma-ray Space Telescope was launched June 11, 2009; since then the Fermi Gamma-ray Burst Monitor (GBM) recorded emission from four magnetar sources. Two of these were brand new sources, SGR J0501+4516, discovered with Swift and extensively monitored with Swift and GBM, SGR J0418+5729, discovered with GBM and the Interplanetary Network (IPN). A third was SGR J1550-5418, a source originally classified as an Anomalous X-ray Pulsar (AXP 1E1547.0-5408), but exhibiting a very prolific outburst with over 400 events recorded in January 2009. In my talk I will give a short history of magnetars and describe how this, once relatively esoteric field, has emerged as a link between several astrophysical areas including Gamma-Ray Bursts. Finally, I will describe the exciting new results of Fermi in this field and the current status of our knowledge of the magnetar population properties and magnetic fields.
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Magnetars: Challenging the Extremes of Nature
NASA Technical Reports Server (NTRS)
Kouveliotou, Chryssa
2011-01-01
Magnetars are magnetically powered rotating neutron stars with extreme magnetic fields (over 10(exp 14) Gauss). They are discovered and emit predominantly in the X- and gamma-rays. Very few sources (roughly 15) have been found since their discovery in 1987. NASA s Fermi Observatory was launched June 11, 2009; the Fermi Gamma Ray Burst Monitor (GBM) began normal operations on July 14, about a month after launch, when the trigger algorithms were enabled. Since then, we recorded emission from four magnetar sources; of these, only one was an old magnetar: SGR 1806+20. The other three detections were two brand new sources, SGR J0501+4516, discovered with Swift and extensively monitored with both Swift and GBM, SGR J0418+5729, discovered with GBM and the Interplanetary Network (IPN), and SGR J1550-5418, a source originally classified as an Anomalous X-ray Pulsar (AXP 1E1547.0-5408). In my talk I will give a short history of the discovery of magnetars and describe how this, once relatively esoteric field, has emerged as a link between several astrophysical areas including Gamma-Ray Bursts. Finally, I will describe the properties of these sources and the current status of our knowledge of the magnetar population and birth rate.
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Performance and biocompatibility of extremely tough alginate/polyacrylamide hydrogels.
Darnell, Max C; Sun, Jeong-Yun; Mehta, Manav; Johnson, Christopher; Arany, Praveen R; Suo, Zhigang; Mooney, David J
2013-11-01
Although hydrogels now see widespread use in a host of applications, low fracture toughness and brittleness have limited their more broad use. As a recently described interpenetrating network (IPN) of alginate and polyacrylamide demonstrated a fracture toughness of ≈ 9000 J/m(2), we sought to explore the biocompatibility and maintenance of mechanical properties of these hydrogels in cell culture and in vivo conditions. These hydrogels can sustain a compressive strain of over 90% with minimal loss of Young's Modulus as well as minimal swelling for up to 50 days of soaking in culture conditions. Mouse mesenchymal stem cells exposed to the IPN gel-conditioned media maintain high viability, and although cells exposed to conditioned media demonstrate slight reductions in proliferation and metabolic activity (WST assay), these effects are abrogated in a dose-dependent manner. Implantation of these IPN hydrogels into subcutaneous tissue of rats for 8 weeks led to mild fibrotic encapsulation and minimal inflammatory response. These results suggest the further exploration of extremely tough alginate/PAAM IPN hydrogels as biomaterials. © 2013 Elsevier Ltd. All rights reserved.
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2014-01-01
Background Numerous inflammation-related pathways have been shown to play important roles in atherogenesis. Rapid and efficient assessment of the relative influence of each of those pathways is a challenge in the era of “omics” data generation. The aim of the present work was to develop a network model of inflammation-related molecular pathways underlying vascular disease to assess the degree of translatability of preclinical molecular data to the human clinical setting. Methods We constructed and evaluated the Vascular Inflammatory Processes Network (V-IPN), a model representing a collection of vascular processes modulated by inflammatory stimuli that lead to the development of atherosclerosis. Results Utilizing the V-IPN as a platform for biological discovery, we have identified key vascular processes and mechanisms captured by gene expression profiling data from four independent datasets from human endothelial cells (ECs) and human and murine intact vessels. Primary ECs in culture from multiple donors revealed a richer mapping of mechanisms identified by the V-IPN compared to an immortalized EC line. Furthermore, an evaluation of gene expression datasets from aortas of old ApoE-/- mice (78 weeks) and human coronary arteries with advanced atherosclerotic lesions identified significant commonalities in the two species, as well as several mechanisms specific to human arteries that are consistent with the development of unstable atherosclerotic plaques. Conclusions We have generated a new biological network model of atherogenic processes that demonstrates the power of network analysis to advance integrative, systems biology-based knowledge of cross-species translatability, plaque development and potential mechanisms leading to plaque instability. PMID:24965703
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Synthesis and properties of hemicelluloses-based semi-IPN hydrogels.
Peng, Feng; Guan, Ying; Zhang, Bing; Bian, Jing; Ren, Jun-Li; Yao, Chun-Li; Sun, Run-Cang
2014-04-01
Hemicelluloses were extracted from holocellulose of bamboo by alkaline treatment. The phosphorylated poly(vinyl alcohol) (P-PVA) samples with various substitution degrees were prepared through the esterification of PVA and phosphoric acid. A series of hydrogels of semi-interpenetrating polymeric networks (semi-IPN) composed of hemicelluloses-g-poly(acrylic acid) (HM-g-PAA) and the phosphorylated poly(vinyl alcohol) (P-PVA) were prepared by radical polymerization using potassium persulphate (KPS) as initiator. The HM-g-PAA networks were crosslinked by N,N-methylenebisacrylamide (MBA) as a crosslinking agent in the presence of linear P-PVA. FT-IR results confirmed that the hydrogels comprised a porous crosslink structure of P-PVA and HM with side chains that carried carboxylate and phosphorylate groups. SEM observations indicated that the incorporation of P-PVA induced highly porous structure, and P-PVA was uniformly dispersed in the polymeric network. The interior network structures of the semi-IPN matrix became more porous with increasing P-PVA. The TGA results showed that the thermo-decomposing temperature and thermal stability were increased effectively for intruding the chain of P-PVA. The maximum equilibrium swelling ratio of hydrogels in distilled water and 0.9 wt% sodium chloride solutions was up to 1085 g g(-1) and 87 g g(-1), respectively. The compressive strength increased with increasing the MBA/HM and P-PVA/HM ratios, and decreased with the increment of AA/HM ratio. Copyright © 2014 Elsevier B.V. All rights reserved.
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Preface: GRBs and other transient sources: Twenty years of Konus-Wind Experiment
NASA Astrophysics Data System (ADS)
Bochkarev, N.
This special issue of Astronomical and Astrophysical Transactions comprises some of the papers presented at the Ioffe Workshop on Gamma-Ray Bursts and Other Transient Sources: Twenty Years of the Konus-Wind Experiment, which was held at the Ioffe Physico-Technical Institute, St. Petersburg, Russia in September 2014. The issue is dedicated to the memory of Professor Evgenii Pavlovich Mazets (1929-2013) in recognition of his outstanding and significant contribution, as Principal Investigator, of the Russian-American Konus-Wind experiment. The Konus instrument is a gamma-ray burst monitor and it was designed and manufactured at the Ioffe Physico-Technical Institute and was first used in the Venera 11-14 deep space missions in 1978-1983. The next important stage and application of the equipment was in association with the Konus-Wind experiment and the Konus instrument was mounted on board the American spacecraft Wind which was launched in November 1994. Wind's orbit in interplanetary space has proved very effective for the study of flares and other tran-and soft gamma repeaters and also solar sients. The Konus instrument consists of two high sensitivity gamma ray detectors which are positioned and located on the top and bottom of the spacecraft, aligned with the spin axis; the Konus equipment has enabled more than 20 years of constant and uninterrupted surveillance and has produced a very large database pertaining to GRBs. In fact, the Konus-Wind experiment continues to play a significant role in the study of GRBs and is an important source of information and data, as part of the InterPlanetary Network (IPN), together and in synchrony with other active missions/spacecraft (equipped with GRB detectors) including FERMI, SWIFT, AGILE, INTEGRAL.
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Waldeck, H.; Kao, W. J.
2013-01-01
Characterization of the degradation mechanisms and resulting products of biodegradable materials is critical in understanding the behavior of the material including solute transport and biological response. Previous mathematical analyses of a semi-interpenetrating network (sIPN) containing both labile gelatin and a stable cross-linked poly(ethylene glycol) (PEG) network found that diffusion-based models alone were unable to explain the release kinetics of solutes from the system. In this study, degradation of the sIPN and its effect on solute release and swelling kinetics were investigated. The kinetics of the primary mode of degradation, gelatin dissolution, was dependent on temperature, preparation methods, PEGdA and gelatin concentration, and the weight ratio between the gelatin and PEG. The gelatin dissolution rate positively correlated with both matrix swelling and the release kinetics of high-molecular-weight model compound, FITC-dextran. Coupled with previous in vitro studies, the kinetics of sIPN degradation provided insights into the time-dependent changes in cellular response including adhesion and protein expression. These results provide a facile guide in material formulation to control the delivery of high-molecular-weight compounds with concomitant modulation of cellular behavior. PMID:21801489
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Ganguly, Sayan; Maity, Tushar; Mondal, Subhadip; Das, Poushali; Das, Narayan C
2017-02-01
Sequentially prepared semi-interpenetrating polymer network (semi-IPN) has been developed here via Michael type addition of acrylic acid (AA) and 2-acrylamido-2-methylpropane sulfonic acid (AMPS) on to starch. The semi-IPN hydrogel have proficiency in fast water imbibition towards gel network and swelling tunable character with pH alteration in ambient condition. The synthesized gel has been characterized by Fourier transformed infrared spectroscopy (FTIR) to confirm Michael type grafting of monomers on to starch. The surface morphology, observed from Scanning Electron Microscopy (SEM) exhibited corrugated rough surface on hydrogel which enhances the fast water uptake feature by anomalous Fickian case II diffusion mechanism. Grafting reaction also improves its thermal stability which has been confirmed by thermogravimetric analysis (TGA). Biodegradation study with hen egg lysozyme medium reveals the accelerated enzymatic scission of the starch backbone and progressive mass loss. Degradation of the hydrogel around 60% of its primary mass has been observed within 7days. The physicochemical characterizations of this hydrogel suggest this as a promising pH-tunable, biodegradable candidate for control drug delivery vehicle. Copyright © 2016 Elsevier B.V. All rights reserved.
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Zhao, Yu; Chen, Guohua; Sun, Mingkun; Jin, Zhitao; Gao, Congjie
2006-04-01
Hydroxyethyl chitin (HECH) is a water soluble chitin derivative made by etherification of chitin, ethylene chlorohydrin was used as etherification reagent in this reaction. A novel interpenetrating polymer network (IPN) composed of HECH/PAA was prepared. The IR spectra confirmed that HECH/PAA was formed through chemical bond interaction. The sensitivity of this hydrogel to temperature and pH was studied. The swelling ratio of this hydrogel in artificial intestinal juice is much greater than that in artificial gastric juice. The IPN hydrogel exhibited a typical pH-sensitivity, and its degree of swelling ratio increased with the increase of temperature. The sustained-release drug system of Dichlofenac potassium was prepared by using HECH/PAA as the drug carrier. The release experiment showed a perfect release behavior in artificial intestinal juice. This IPN is expected to be used as a good drug delivery system of enteric medicine.
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Tough, processable semi-interpenetrating polymer networks from monomer reactants
NASA Technical Reports Server (NTRS)
Pater, Ruth H. (Inventor)
1994-01-01
A high temperature semi-interpenetrating polymer network (semi-IPN) was developed which had significantly improved processability, damage tolerance, and mechanical performance, when compared to the commercial Thermid materials. This simultaneous semi-IPN was prepared by mixing the monomer precursors of Thermid AL-600 (a thermoset) and NR-150B2 (a thermoplastic) and allowing the monomers to react randomly upon heating. This reaction occurs at a rate which decreases the flow and broadens the processing window. Upon heating at a higher temperature, there is an increase in flow. Because of the improved flow properties, broadened processing window and enhanced toughness, high strength polymer matrix composites, adhesives and molded articles can now be prepared from the acetylene end-capped polyimides which were previously inherently brittle and difficult to process.
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Xu, Yifei; Ghag, Onkar; Reimann, Morgan; Sitterle, Philip; Chatterjee, Prithwish; Nofen, Elizabeth; Yu, Hongyu; Jiang, Hanqing; Dai, Lenore L
2017-12-20
An interpenetrating polymer network (IPN), chlorophyllin-incorporated environmentally responsive hydrogel was synthesized and exhibited the following features: enhanced mechanical properties, upper critical solution temperature (UCST) swelling behavior, and promising visible-light responsiveness. Poor mechanical properties are known challenges for hydrogel-based materials. By forming an interpenetrating network between polyacrylamide (PAAm) and poly(acrylic acid) (PAAc) polymer networks, the mechanical properties of the synthesized IPN hydrogels were significantly improved compared to hydrogels made of a single network of each polymer. The formation of the interpenetrating network was confirmed by Fourier Transform Infrared Spectroscopy (FTIR), the analysis of glass transition temperature, and a unique UCST responsive swelling behavior, which is in contrast to the more prevalent lower critical solution temperature (LCST) behaviour of environmentally responsive hydrogels. The visible-light responsiveness of the synthesized hydrogel also demonstrated a positive swelling behavior, and the effect of incorporating chlorophyllin as the chromophore unit was observed to reduce the average pore size and further enhance the mechanical properties of the hydrogel. This interpenetrating network system shows potential to serve as a new route in developing "smart" hydrogels using visible-light as a simple, inexpensive, and remotely controllable stimulus.
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In Vitro Wear Resistance of Nano-Hybrid Composite Denture Teeth.
Munshi, Nabeel; Rosenblum, Marc; Jiang, Shuying; Flinton, Robert
2017-04-01
To evaluate the wear resistance of nano-hybrid composite denture teeth as compared to two commonly used denture teeth: interpenetrating polymer network (IPN) and double crosslinking polymethylmethacrylate (PMMA) denture teeth. 18 styli and 18 disk specimens were prepared from the three denture tooth materials: nano-hybrid composite, IPN, and double crosslinking PMMA. The specimens were mounted in a two-body wear testing machine to simulate chewing in the complete denture. The amount of wear from the styli specimens were measured before and after using a digital micrometer, and the depth of the wear track from the disk specimens was measured using a noncontact 3D optical profilometer. The total wear from each denture tooth group was compared using one-way ANOVA with a 0.05 significance level. A Tukey post hoc test was used to determine differences between the three groups. The mean total wear in the nano-hybrid composite teeth group was 1.16 mm, SD = 0.5 mm, statistically significantly higher (p ≤ 0.0001) than the IPN (mean = 0.13 mm, SD = 0.05) and double crosslinking PMMA tooth groups (mean = 0.31 mm, SD = 0.19). There was no statistically significant difference between IPN denture teeth and double crosslinking PMMA denture teeth in the amount of wear. Nano-hybrid composite denture teeth exhibited statistically significantly more wear than the IPN and double crosslinking PMMA denture teeth. © 2015 by the American College of Prosthodontists.
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NASA Astrophysics Data System (ADS)
Geng, Xing
2005-07-01
A research area of high activity in connection with aerospace engineering has been the development of polymer thermosetting resins that can withstand temperature as high as 300°C while maintaining adequate toughness and providing ease of processing to enable low temperature and low cost composite fabrication methods. In order to meet such requirements, sequential interpenetrating polymer networks (IPNs) based on bismaleimide (BMI) and cyanate ester (CE) monomers were investigated. In these systems, a polycyanurate network is first formed in the presence of BMI and appropriate reactive diluent monomers and, in a second step, a network based on the BMI is created in the presence of a fully formed polycyanurate network. The materials developed can be processed at relatively low temperature (<150°C) and with the aid of electron beam (EB) curing. Of major importance to the success of this work was the identification of a reactive diluent that improves ease of processing and has tailored reactivity to allow for the controlled synthesis of CE-BMI sequential IPNs. Based on solubility and reactivity of a number of reactive diluents, N-acryloylmorpholine (AMP) was selected as a co-monomer for BMI copolymerization. A donor-acceptor reaction mechanism was suggested to explain the relative reactivity of a variety of reactive diluents towards maleimide functionality. The optimum processing parameters for the formation of the first network were determined through the study of metal catalyzed cure and hydrolysis of cyanate esters, whereas the reaction behavior for second network formation in terms of the influence of EB dose rate and temperature was elucidated through an in-situ kinetics study of maleimide and AMP copolymerization. Structure-property relationships were developed which allowed for the design of improved resin systems. In particular, an appropriate network coupler possessing cyanate ester and maleimide functionality was synthesized to link the polycyanurate first network to the BMI/AMP second network and thus form linked sequential IPNs (LIPNs). Consequently, Tg as high as 370°C was achieved and a fracture toughness of 120 J/m2 was obtained for resin systems that possess adequately low viscosity for processing using liquid molding techniques at low temperature.
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Lou, Junzhe; Stowers, Ryan; Nam, Sungmin; Xia, Yan; Chaudhuri, Ovijit
2018-02-01
The physical and architectural cues of the extracellular matrix (ECM) play a critical role in regulating important cellular functions such as spreading, migration, proliferation, and differentiation. Natural ECM is a complex viscoelastic scaffold composed of various distinct components that are often organized into a fibrillar microstructure. Hydrogels are frequently used as synthetic ECMs for 3D cell culture, but are typically elastic, due to covalent crosslinking, and non-fibrillar. Recent work has revealed the importance of stress relaxation in viscoelastic hydrogels in regulating biological processes such as spreading and differentiation, but these studies all utilize synthetic ECM hydrogels that are non-fibrillar. Key mechanotransduction events, such as focal adhesion formation, have only been observed in fibrillar networks in 3D culture to date. Here we present an interpenetrating network (IPN) hydrogel system based on HA crosslinked with dynamic covalent bonds and collagen I that captures the viscoelasticity and fibrillarity of ECM in tissues. The IPN hydrogels exhibit two distinct processes in stress relaxation, one from collagen and the other from HA crosslinking dynamics. Stress relaxation in the IPN hydrogels can be tuned by modulating HA crosslinker affinity, molecular weight of the HA, or HA concentration. Faster relaxation in the IPN hydrogels promotes cell spreading, fiber remodeling, and focal adhesion (FA) formation - behaviors often inhibited in other hydrogel-based materials in 3D culture. This study presents a new, broadly adaptable materials platform for mimicking key ECM features of viscoelasticity and fibrillarity in hydrogels for 3D cell culture and sheds light on how these mechanical and structural cues regulate cell behavior. Copyright © 2017 Elsevier Ltd. All rights reserved.
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Three Decades of High Energy Transients
NASA Technical Reports Server (NTRS)
Kouveliotou, Chryssa
2012-01-01
Gamma-Ray Bursts are the most brilliant explosions in space. The first GRB was discovered on 1967, just over 40 years ago. It took several years and multiple generations of space and ground instruments to unravel some of the mysteries of this phenomenon. However, many questions remain open today. I will discuss the history, evolution and current status of the GRB field and its contributions in our understanding of the transient high energy sky. Finally, I will describe how GRBs can be utilized in future missions as tools, to probe the cosmic chemical evolution of the Universe Magnetars are magnetically powered rotating neutron stars with extreme magnetic fields (over 10(exp 14) Gauss). They were discovered in the X- and gamma-rays where they predominantly emit their radiation. Very few sources (roughly 24) have been found since their discovery in 1987. NASA's Fermi Gamma-ray Space Telescope was launched June 11, 2009; since then the Fermi Gamma-ray Burst Monitor (GBM) recorded emission from several magnetar sources. In total, six new sources were discovered between 2008 and 2011, with a synergy between Swift, RXTE, Fermi and the Interplanetary Network (IPN). I will give a short history of magnetars and describe how this, once relatively esoteric field, has emerged as a link between several astrophysical areas including Gamma-Ray Bursts.
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Dongargaonkar, Alpana A.; Bowlin, Gary L.; Yang, Hu
2013-01-01
In this work, we report a new nanofiber construct based on electrospun blends of gelatin and gelatin-dendrimer conjugates. Highly branched star-shaped polyamidoamine (PAMAM) dendrimer G3.5 was covalently conjugated to gelatin via EDC/NHS chemistry. Blends of gelatin and gelatin-dendrimer conjugates mixed with various loading levels of silver acetate (0, 0.83, 1.65, and 3.30% w/w) were successfully electrospun into nanofiber constructs (NCs). The NCs were further converted into semi-interpenetrating networks (sIPNs) with photoreactive polyethylene glycol diacrylate (Mn=575 gmol-1) (PEG DA575). They were characterized in terms of fiber morphology, diameter, pore size, permeability, degradation, and mechanical properties. The resulting sIPN NCs retained nanofiber morphology, possessed similar fiber diameters to counterpart NCs, and gained improved structural stability. The sIPN NCs also showed good swelling capacity owing to porous structures and were permeable to aqueous solutions. Silvercontaining sIPN NCs allowed sustained silver release and showed antimicrobial activity against two common types of pathogens—Staphylococcus aureus and Pseudomonas aeruginosa. Incorporation of dendrimers into the gelatin nanofibers through covalent conjugation not only expands drug loading capacity of nanofiber constructs but provides tremendous flexibility for developing multifunctional electrospun dressing materials. PMID:24127747
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A novel method of fabricating laminated silicone stack actuators with pre-strained dielectric layers
NASA Astrophysics Data System (ADS)
Hinitt, Andrew D.; Conn, Andrew T.
2014-03-01
In recent studies, stack based Dielectric Elastomer Actuators (DEAs) have been successfully used in haptic feedback and sensing applications. However, limitations in the fabrication method, and materials used to con- struct stack actuators constrain their force and displacement output per unit volume. This paper focuses on a fabrication process enabling a stacked elastomer actuator to withstand the high tensile forces needed for high power applications, such as mimetics for mammalian muscle contraction (i.e prostheses), whilst requiring low voltage for thickness-mode contractile actuation. Spun elastomer layers are bonded together in a pre-strained state using a conductive adhesive filler, forming a Laminated Inter-Penetrating Network (L-IPN) with repeatable and uniform electrode thickness. The resulting structure utilises the stored strain energy of the dielectric elas- tomer to compress the cured electrode composite material. The method is used to fabricate an L-IPN example, which demonstrated that the bonded L-IPN has high tensile strength normal to the lamination. Additionally, the uniformity and retained dielectric layer pre-strain of the L-IPN are confirmed. The described method is envisaged to be used in a semi-automated assembly of large-scale multi-layer stacks of pre-strained dielectric layers possessing a tensile strength in the range generated by mammalian muscle.
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NASA Technical Reports Server (NTRS)
Palmese, Giuseppe R.; Meador, Michael A. (Technical Monitor)
2005-01-01
A research area of high activity in connection with aerospace engineering has been the development of polymer thermosetting resins that can resist temperature as high as 300 C while maintaining adequate toughness, and providing ease of processing to enable low temperature and low cost composite fabrication methods. In order to meet such requirements, sequential interpenetrating polymer networks (IPNs) based on bismaleimide (BMI) and cyanate ester (CE) monomers were investigated. In these systems, a polycyanurate network is first formed in the presence of BMI and appropriate reactive diluent monomers and in a second step, a network based on the BMI is created in the presence of a fully formed polycyanurate network. The materials developed can be processed at relatively low temperature (less than 150 C) and with the aid of electron beam (EB) curing. Of major importance to the success of this work was the identification of a reactive diluent that improves ease of processing and has tailored reactivity to allow for the controlled synthesis of CE-BMI sequential IPNs. Based on solubility and reactivity of a number of reactive diluents, N-acryloylmorpholine (AMP) was selected as a comonomer for BMI copolymerization. A donor-acceptoreaction mechanism was suggested to explain the relative reactivity of a variety of reactive diluents towards maleimide functionality. The optimum processing parameters for the formation of the first network were determined through the study of metal catalyzed cure and hydrolysis of cyanate esters, whereas the reaction behavior for second network formation in terms of the influence of EB dose rate and temperature was elucidated through an in-situ kinetics study of maleimide and AMP copolymerization. Structure-property relationships were developed which allowed for the design of improved resin systems. In particular, appropriate network coupler possessing cyanate ester and maleimide functionality was synthesized to link the polycyanurate first network to the BMI/AMP second network and thus form linked sequential IPNs (LIPNs). Consequently, Tg as high as 370 C was achieved and a fracture toughness of 120 Joules per square meters was obtained for resin systems that possess adequately low viscosity for processing using liquid molding techniques at low temperature.
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Bhattacharya, Shiv Sankar; Mazahir, Farhan; Banerjee, Subham; Verma, Anurag; Ghosh, Amitava
2013-10-15
Interpenetrating polymer network (IPN) hydrogel microspheres of xanthan gum (XG) based superabsorbent polymer (SAP) and poly(vinyl alcohol) (PVA) were prepared by water-in-oil (w/o) emulsion crosslinking method for sustained release of ciprofloxacin hydrochloride (CIPRO). The microspheres were prepared with various ratios of hydrolyzed SAP to PVA and extent of crosslinking density. The prepared microspheres with loose and rigid surfaces were evidenced by scanning electron microscope (SEM). Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) analysis confirmed the IPN formation. Differential scanning calorimetry (DSC) study was performed to understand the dispersion nature of drug after encapsulation. The in vitro drug release study was extensively evaluated depending on the process variables in both acidic and alkaline media. All the formulations exhibited satisfactory physicochemical and in vitro release characteristics. Release data indicated a non-Fickian trend of drug release from the formulations. Based on the results, this study suggest that CIPRO loaded IPN microspheres were suitable for sustained release application. Copyright © 2013 Elsevier Ltd. All rights reserved.
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Xiang, Yang; Ru, Xudong; Shi, Jinguo; Song, Jiang; Zhao, Haidong; Liu, Yaqing; Guo, Dongdong; Lu, Xin
2017-12-20
A new semi-interpenetrating polymer network (semi-IPN) slow-release fertilizer (SISRF) with water absorbency, based on the kaolin-g-poly(acrylic acid-co-acrylic amide) (kaolin-g-P(AA-co-AM)) network and linear urea-formaldehyde oligomers (UF), was prepared by solution polymerization. Nutrients phosphorus and potassium were supplied by adding dipotassium hydrogen phosphate during the preparation process. The structure and properties of SISRF were characterized by various characterization methods. SISRF showed excellent water absorbency of 68 g g -1 in tap water. The slow-release behavior of nutrients and water-retention capacity of SISRF were also measured. Meanwhile, the swelling kinetics was well described by a pseudo-second-order kinetics model. Results suggested the formation of SISRF with simultaneously good slow-release and water-retention capacity, which was expected to apply in modern agriculture and horticulture.
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Thermo-responsive gels that absorb moisture and ooze water.
Matsumoto, Kazuya; Sakikawa, Nobuki; Miyata, Takashi
2018-06-13
The water content of thermo-responsive hydrogels can be drastically altered by small changes in temperature because their polymer chains change from hydrophilic to hydrophobic above their low critical solution temperature (LCST). In general, such smart hydrogels have been utilized in aqueous solutions or in their wet state, and no attempt has been made to determine the phase-transition behavior of the gels in their dried states. Here we demonstrate an application of the thermo-responsive behavior of an interpenetrating polymer network (IPN) gel comprising thermo-responsive poly(N-isopropylacrylamide) and hydrophilic sodium alginate networks in their dried states. The dried IPN gel absorbs considerable moisture from air at temperatures below its LCST and oozes the absorbed moisture as liquid water above its LCST. These phenomena provide energy exchange systems in which moisture from air can be condensed to liquid water using the controllable hydrophilic/hydrophobic properties of thermo-responsive gels with a small temperature change.
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Barber, Thomas A; Ho, James E; De Ranieri, Aladino; Virdi, Amarjit S; Sumner, Dale R; Healy, Kevin E
2007-02-01
Interpenetrating polymer networks (IPNs) of poly (acrylamide-co-ethylene glycol/acrylic acid) functionalized with an -Arg-Gly-Asp- (RGD) containing 15 amino acid peptides, derived from rat bone sialoprotein (bsp-RGD(15), were grafted to titanium implants in an effort to modulate bone formation in the peri-implant region in the rat femoral ablation model. Bone-implant contact (BIC) and bone formation within the medullary canal were determined using microcomputed tomography at 2 and 4 weeks postimplantation. BIC for bsp-RGD(15)-IPN implants was enhanced relative to hydroxyapatite tricalcium phosphate (HA-TCP) coated implants, but was similar to all other groups. Aggregate bone formation neither indicated a dose-dependent effect of bsp-RGD(15) nor a meaningful trend. Mechanical testing of implant fixation revealed that only the HA-TCP coated implants supported significant (>1 MPa) interfacial shear strength, despite exhibiting lower overall BIC, an indication that bone ingrowth into the rougher coating was the primary mode of implant fixation. While no evidence was found to support the hypothesis that bsp-RGD(15)-modified IPN coated implants significantly impacted bone-implant bonding, these results point to the lack of correlation between in vitro studies employing primary osteoblasts and in vivo wound healing in the peri-implant region. Copyright 2006 Wiley Periodicals, Inc.
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Robison, Nathan E; Tantbirojn, Daranee; Versluis, Antheunis; Cagna, David R
2016-08-01
Denture tooth fracture or debonding remains a common problem in removable prosthodontics. The purpose of this in vitro study was to explore factors determining failure strengths for combinations of different denture tooth designs (shape, materials) and injection or compression molded denture base resins. Three central incisor denture tooth designs were tested: nanohybrid composite (NHC; Ivoclar Phonares II), interpenetrating network (IPN; Dentsply Portrait), and microfiller reinforced polyacrylic (MRP; VITA Physiodens). Denture teeth of each type were processed on an injection molded resin (IvoBase HI; Ivoclar Vivadent AG) or a compression molded resin (Lucitone 199; Dentsply Intl) (n=11 or 12). The denture teeth were loaded at 45 degrees on the incisal edge. The failure load was recorded and analyzed with 2-way ANOVA (α=.05), and the fracture mode was categorized from observed fracture surfaces as cohesive, adhesive, or mixed failure. The following failure loads (mean ±SD) were recorded: NHC/injection molded 280 ±52 N; IPN/injection molded 331 ±41 N; MRP/injection molded 247 ±23 N; NHC/compression molded 204 ±31 N; IPN/compression molded 184 ±17 N; MRP/compression molded 201 ±16 N. Injection molded resin yielded significantly higher failure strength for all denture teeth (P<.001), among which IPN had the highest strength. Failure was predominantly cohesive in the teeth, with the exception of mixed mode for the IPN/compression group. When good bonding was achieved, the strength of the structure (denture tooth/base resin combination) was determined by the strength of the denture teeth, which may be affected by the processing technique. Copyright © 2016 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.
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Tough, processable simultaneous semi-interpenetrating polyimides
NASA Technical Reports Server (NTRS)
Pater, Ruth H. (Inventor)
1996-01-01
A high temperature semi-interpenetrating polymer network (semi-IPN) was developed which had significantly improved processability, damage tolerance and mechanical performance, when compared to the commercial Thermid.RTM. materials. This simultaneous semi-IPN was prepared by mixing a thermosetting polyimide with a thermoplastic monomer precursor solution (NR-15082) and allowing them to react upon heating. This reaction occurs at a rate which decreases the flow and broadens the processing window. Upon heating at a higher temperature, there is an increase in flow. Because of the improved flow properties, broadened processing window and enhanced toughness, high strength polymer matrix composites, adhesives and molded articles can now be prepared from the acetylene endcapped polyimides which were previously inherently brittle and difficult to process.
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IPNS progress report 2001-2006.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Marzec, B.
In August 1981, the proton beam from the rapid cycling synchrotron (RCS) was first delivered to the Intense Pulsed Neutron Source (IPNS) neutron scattering target and now, in June 2006, it is with great joy that we celebrate the impending 25th anniversary of this event. This edition of the IPNS Progress Report will focus on the development and scientific accomplishments of the past 5 years, since our last Progress Report, but with some mention of the 25 years of IPNS experience. It is appropriate at this anniversary date to recall some of the more significant historic events that have ledmore » to the present IPNS and discuss some of the plans that will lead to even more successes. Below is a brief chronology that captures some of the developments of IPNS: 8/4/81 - First beam delivered to the neutron scattering target; 6/10/84 - IPNS produced its one billionth neutron pulse; 1/10/85 - Installed world's first solid methane moderator; 6/30/87 - 1000th experiment performed at IPNS; 9/19/87 - IPNS produced its two billionth neutron pulse; 11/20/91 - 2000th experiment performed at IPNS; 4/17/04 - IPNS produced its eight billionth neutron pulse; and 8/19/05 - 7000th experiment performed at IPNS. During the past 5 years, several significant source and instrument developments have taken place. Most of these are discussed in more detail elsewhere in the report, but three of the ones most visible to users are mentioned here.« less
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Zhang, Heng; Gao, Xin; Chen, Keli; Li, Hui; Peng, Lincai
2018-02-01
In current study, cellouronic acid sodium (CAS), obtained from bagasse pith, has been introduced into poly(acrylamide-co-diallyldimethylammonium chloride) (poly(AM-co-DAC)) network to form novel thermo-sensitive semi-IPNs. The structure and morphology of the hydrogels were proved by Fourier transformation infrared spectroscopy (FT-IR), X-ray photoelectron spectroscopy (XPS) and scanning electron microscopy (SEM). The effects of CAS content, initiator charge, cross-linker dosage and swelling-medium property on the thermo-responsive water absorptivity were investigated in detail. The results elucidated that the prepared gels exhibited a thermo-sensibility with an upper critical solution temperature (UCST) and a high water-absorbency. And the values of UCST and equilibrium swelling ratio largely depended on the inner structure of the semi-IPNs and the external solvent property. It was also revealed that the swelling process conformed to the Schott's pseudo second order model and diffusion type was non-Fickian diffusion. The value of activation energy for this polyelectrolyte was found to be 8.74kJ/mol. Copyright © 2017 Elsevier Ltd. All rights reserved.
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Keratin sponge/hydrogel II, active agent delivery
USDA-ARS?s Scientific Manuscript database
Keratin sponge/hydrogels from oxidation and reduction hydrolysis of fine and coarse wool fibers were formed to behave as cationic hydrogels to swell and release active agents in the specific region of the gastro-intestinal (GI) tract. Their porous, interpenetrating networks (IPN) were effective for...
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Tough, processable simultaneous semi-interpenetrating polyimides
NASA Technical Reports Server (NTRS)
Pater, Ruth H. (Inventor)
1994-01-01
A high temperature semi-interpenetrating polymer network (semi-IPN) was developed which had significantly improved processability, damage tolerance, and mechanical performance when compared to the commercial Thermid materials. This simultaneous semi-IPN was prepared by mixing a thermosetting polyimide with a thermoplastic monomer precursor solution (NR150B2) and allowing them to react upon heating. This reaction occurs at a rate which decreases the flow and broadens the processing window. Upon heating at a higher temperature, there is an increase in flow. Because of the improved flow properties, broadened processing window and enhanced toughness, high strength polymer matrix composites, adhesives and molded articles can now be prepared from the acetylene endcapped polyimides which were previously inherently brittle and difficult to process.
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Simulating Autonomous Telecommunication Networks for Space Exploration
NASA Technical Reports Server (NTRS)
Segui, John S.; Jennings, Esther H.
2008-01-01
Currently, most interplanetary telecommunication systems require human intervention for command and control. However, considering the range from near Earth to deep space missions, combined with the increase in the number of nodes and advancements in processing capabilities, the benefits from communication autonomy will be immense. Likewise, greater mission science autonomy brings the need for unscheduled, unpredictable communication and network routing. While the terrestrial Internet protocols are highly developed their suitability for space exploration has been questioned. JPL has developed the Multi-mission Advanced Communications Hybrid Environment for Test and Evaluation (MACHETE) tool to help characterize network designs and protocols. The results will allow future mission planners to better understand the trade offs of communication protocols. This paper discusses various issues with interplanetary network and simulation results of interplanetary networking protocols.
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Liu, Jia; Su, Yuan; Li, Qian; Yue, Qinyan; Gao, Baoyu
2013-09-01
A novel wheat straw cellulose-g-poly (potassium acrylate)/polyvinyl alcohol (WSC-g-PKA/PVA) semi-interpenetrating polymer networks (semi-IPNs) superabsorbent resin (SAR) was prepared by graft copolymerization. The structure and performance of the WSC-g-PKA/PVA semi-IPNs SAR was studied and compared with those of wheat straw cellulose-g-poly (potassium acrylate) (WSC-g-PKA) SAR. The effects of various experimental parameters such as solution pH, concentration, contact time and ion strength on NH4(+) and PO4(3-) removal from solutions were investigated. Equilibrium isotherm data of adsorption of both NH4(+) and PO4(3-) were well fitted to the Freundlich model. Kinetic analysis showed that the pseudo-second-order kinetic model was more suitable for describing the whole adsorption process of NH4(+) and PO4(3-) on SARs. Overall, WSC-g-PKA/PVA semi-IPNs SAR showed better properties in comparison with WSC-g-PKA SAR and it could be considered as one efficient material for the removal and recovery of nitrogen and phosphorus with the agronomic reuse as a fertilizer. Copyright © 2013 Elsevier Ltd. All rights reserved.
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Poly(Ionic Liquid) Semi-Interpenetrating Network Multi-Responsive Hydrogels
Tudor, Alexandru; Florea, Larisa; Gallagher, Simon; Burns, John; Diamond, Dermot
2016-01-01
Herein we describe poly(ionic liquid) hydrogel actuators that are capable of responding to multiple stimuli, namely temperature, ionic strength and white light irradiation. Using two starting materials, a crosslinked poly ionic liquid (PIL) and a linear poly(N-isopropylacrylamide-co-spiropyran-co-acrylic acid), several semi-interpenetrating (sIPN) hydrogels were synthesised. The dimensions of hydrogels discs were measured before and after applying the stimuli, to quantify their response. Samples composed of 100% crosslinked PIL alone showed an average area reduction value of ~53% when the temperature was raised from 20 °C to 70 °C, ~24% when immersed in 1% w/w NaF salt solution and no observable photo-response. In comparison, sIPNs containing 300% w/w linear polymer showed an average area reduction of ~45% when the temperature was raised from 20 °C to 70 °C, ~36% when immersed in 1% NaF w/w salt solution and ~10% after 30 min exposure to white light irradiation, respectively. Moreover, by varying the content of the linear component, fine-control over the photo-, thermo- and salt response, swelling-deswelling rate and mechanical properties of the resulting sIPN was achieved. PMID:26861339
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Distributed Interplanetary Delay/Disruption Tolerant Network (DTN) Monitor and Control System
NASA Technical Reports Server (NTRS)
Wang, Shin-Ywan
2012-01-01
The main purpose of Distributed interplanetary Delay Tolerant Network Monitor and Control System as a DTN system network management implementation in JPL is defined to provide methods and tools that can monitor the DTN operation status, detect and resolve DTN operation failures in some automated style while either space network or some heterogeneous network is infused with DTN capability. In this paper, "DTN Monitor and Control system in Deep Space Network (DSN)" exemplifies a case how DTN Monitor and Control system can be adapted into a space network as it is DTN enabled.
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Proceedings of Damping 89, Volume 2, West Palm Beach, FL, 8-10 February 1989
1989-11-01
Vinyl Methyl Ether)-Polystyrene Blends and IPN’s J. J. Fay, Dr. C. J. Murphy, Dr. D. A. Thomas and Prof. L. H. Sperling BAA Time-Temperature...Structural Vibrations with Piezoelectric Materials and Passive Electrical Networks N. W. Hagood and Prof. A. von Flotow ICC Passive Electromagnetic
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Forecast the energetic electron flux on geosynchronous orbit with interplanetary parameters
NASA Astrophysics Data System (ADS)
Xue, B.; Ye, Z.
The high flux of energetic electron on geo-synchronous orbit can cause many kinds of malfunction of the satellite there, within which the bulk charging is the most significant that several broadcast satellite failures were confirmed to be due to this effect. The electron flux on geo-synchronous orbit varies in a large range even up to three orders accompanied the passage of interplanetary magnetic cloud and the following geomagnetic disturbances. Upon investigating electron flux, interplanetary solar wind data, and geomagnetic data as well, we found that: (1) The enhancement of energetic flux on the geo-synchronous orbit exhibits periodic recurrence of 27days. (2)Significant increase of electron flux relates to interplanetary index and characters of their distribution. (3)The electron flux also has relation to solar activity index. In our research work, artificial neural network was employed and constructed according to the job. The neural network, we call it full connecting network, was proved to be a sufficient tool to analyze the character of the evolving parameters, remember the omen of "electron storm", and establish the relationship between interplanetary parameters etc., and the fluence of high energetic electrons. The neural network was carefully constructed and trained to do the job mentioned above. Preliminary result showed that the accuracy forecast of electron flux 1 day ahead can reach 80%, and 70% for 2 days ahead.
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In vitro characterization of peptide-modified p(AAm-co-EG/AAc) IPN-coated titanium implants.
Barber, Thomas A; Gamble, Lara J; Castner, David G; Healy, Kevin E
2006-07-01
Interpenetrating polymer networks (IPNs) of poly(acrylamide-co-ethylene glycol/acrylic acid) [p(AAm-co-EG/AAc)] functionalized with an -Arg-Gly-Asp- containing peptide derived from rat bone sialoprotein [bsp-RGD(15)] were grafted to titanium implants in an effort to modulate osteoblast behavior in vitro. Surface characterization data were consistent with the presence of an IPN, and ligand density measurements established that the range of peptide density on the modified implants spanned three orders of magnitude (0.01-20 pmol/cm2). In vitro biological characterization of the modified implants employing the primary rat calvarial osteoblast (RCO) model resulted in the identification of a critical ligand density (0.01
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Chan, Ka Man Carmen; Li, Randolph H.; Chapman, Joseph W.; Trac, Eric M.; Kobler, James B.; Zeitels, Steven M.; Langer, Robert; Karajanagi, Sandeep S.
2014-01-01
Particle size, stiffness and surface functionality are important in determining the injection site, safety and efficacy of injectable soft-tissue fillers. Methods to produce soft injectable biomaterials with controlled particle characteristics are therefore desirable. Here we report a method based on suspension photopolymerization and semi-interpenetrating network (semi-IPN) to synthesize soft, functionalizable, spherical hydrogel microparticles (MP) of independently tunable size and stiffness. MP were prepared using acrylated forms of polyethylene glycol (PEG), gelatin and hyaluronic acid. Semi-IPN MP of PEG-diacrylate and PEG were used to study the effect of process parameters on particle characteristics. The process parameters were systematically varied to produce MP with size ranging from 115 to 515 μm and stiffness ranging from 190 to 1600 Pa. In vitro studies showed that the MP thus prepared were cytocompatible. The ratio and identity of the polymers used to make the semi-IPN MP were varied to control their stiffness and to introduce amine groups for potential functionalization. Slow-release polymeric particles loaded with Rhodamine or dexamethasone were incorporated in the MP as a proof-of-principle of drug incorporation and release from the MP. This work has implications in preparing injectable biomaterials of natural or synthetic polymers for applications as soft-tissue fillers. PMID:24561708
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The Indigenous Phenology Network: Engage, Observe, and Adapt to Change
NASA Astrophysics Data System (ADS)
Miller, B. W.; Davíd-Chavez, D. M.; Elevitch, C.; Hamilton, A.; Hatfield, S. C.; Jones, K. D.; Rabin, R.; Rosemartin, A.; Souza, M. K.; Sparrow, E.
2017-12-01
The Indigenous Phenology Network (IPN) is a grassroots organization whose participants are interested in understanding changes to seasonality and timing of life cycle events, and forecasting impacts to lands and species of importance to native peoples. The group focuses on building relationships, ensuring benefit to indigenous communities, and integrating indigenous and western knowledge systems. The IPN's work is guided by the Relational Doctrine, a set of principles founded on the notion that all things are connected. This multimedia presentation and dialogue will bring together IPN members and their experiences in diverse communities and landscapes facing impacts from a changing climate and extreme weather events. Impacts on water supply, vegetation, wildlife, and living conditions, and ideas for minimizing and responding to the projected impacts of continued change will be discussed in the context of multi-generational, place-based traditional knowledge and community resilience. Scalable, community-based gardens, for example, provide a sustainable source of traditional, locally grown food, most valuable in times of disaster when supplies from the outside world are unavailable. Following the concept of Victory Gardens, the model of small-scale agroforestry (VICTree Gardens - Virtually Interconnected Community Tree Gardens), being implemented in Hawaii, has the potential to provide a diverse diet of food grown in very limited space. Gardens build resilience by connecting people with each other, with local food, and with nature. We envision community-based projects which will apply local, multi-generational knowledge to adapt the gardens to changing environments. Going forward, direct observation of garden conditions can be combined with satellite and ground-based measurements of environmental conditions, such as soil moisture, soil and air temperature, precipitation, and phenology, to further assess and manage these gardens in the context of the surrounding landscape.
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2013-07-05
oven for the same curing treatment as before. The scanning electron microscope (SEM) photo in Figure 19 shows a typical sample with TMSPM and IPTES...Methacrylate-based Polymers,’ S. A . Bird , PhD Dissertation, Department of Polymer and Fiber Engineering, Auburn University, Summer 2013. ’Fracture Behavior...Polymer Networks with Polyurethane-poly(methyl methacrylate),’ K. C. Jajam, S. A . Bird , M. L. Auad, and H. V. Tippur, Polymer Testing, Vol. 32, pp
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2014-02-01
samples were placed into the oven for the same curing treatment as before. The scanning electron microscope (SEM) photo in Figure 19 shows a typical...Interpenetrating Polymer Networks with Polyurethane and Methacrylate-based Polymers,’ S. A . Bird , PhD Dissertation, Department of Polymer and Fiber Engineering...Jajam, H. V. Tippur, S. A . Bird , and M. L. Auad, Proceedings of the 50th SES Annual Technical Meeting and ASME-AMD Summer Meeting, Providence, RI
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Semi-interpenetrating polymer network's of polyimides: Fracture toughness
NASA Technical Reports Server (NTRS)
Hansen, Marion Glenn
1988-01-01
The objective was to improve the fracture toughness of the PMR-15 thermosetting polyimide by co-disolving LaRC-TPI, a thermoplastic polyimide. The co-solvation of a thermoplastic into a thermoset produces an interpenetration of the thermoplastic polymer into the thermoset polyimide network. A second research program was planned around the concept that to improve the fracture toughness of a thermoset polyimide polymer, the molecular weight between crosslink points would be an important macromolecular topological parameter in producing a fracture toughened semi-IPN polyimide.
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Reduced lymphocyte count as an early marker for predicting infected pancreatic necrosis.
Shen, Xiao; Sun, Jing; Ke, Lu; Zou, Lei; Li, Baiqiang; Tong, Zhihui; Li, Weiqin; Li, Ning; Li, Jieshou
2015-10-26
Early occurrence of immunosuppression is a risk factor for infected pancreatic necrosis (IPN) in the patients with acute pancreatitis (AP). However, current measures for the immune systems are too cumbersome and not widely available. Significantly decreased lymphocyte count has been shown in patients with severe but not mild type of AP. Whereas, the correlation between the absolute lymphocyte count and IPN is still unknown. We conduct this study to reveal the exact relationship between early lymphocyte count and the development of IPN in the population of AP patients. One hundred and fifty-three patients with acute pancreatitis admitted to Jinling Hospital during the period of January 2012 to July 2014 were included in this retrospective study. The absolute lymphocyte count and other relevant parameters were measured on admission. The diagnosis of IPN was based on the definition of the revised Atlanta classification. Patients were divided into two groups according to the presence of IPN. Thirty patients developed infected necrotizing pancreatitis during the disease course. The absolute lymphocyte count in patients with IPN was significantly lower on admission (0.62 × 10(9)/L, interquartile range [IQR]: 0.46-0.87 × 10(9)/L vs. 0.91 × 10(9)/L, IQR: 0.72-1.27 × 10(9)/L, p < 0.001) and throughout the whole clinical course than those without IPN. Logistic regression indicated that reduced lymphocyte count was an independent risk factor for IPN. The optimal cut-offs from ROC curve was 0.66 × 10(9)/L giving sensitivity of 83.7 % and specificity of 66.7 %. Reduced lymphocyte count within 48 h of AP onset is significantly and independently associated with the development of IPN.
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NASA Astrophysics Data System (ADS)
Dewantara, Fauzi; Budianto, Emil
2018-04-01
Chitosan-methyl cellulose semi-IPN hydrogel is used as floating drug delivery system, and calcium carbonate also added as pore forming agent. The hydrogel network arranged by not only using biopolymer chitosan and methyl cellulose, but also the crosslink agent that is glutaraldehyde. Amoxicillin trihydrate entrapped into the polymer network with two different method, in situ loading and post loading. Furthermore both method has been tested for drug entrapment efficiency along with drug dissolution test, and the result for drug entrapment efficiency is in situ loading method has highest value of 100%, compared to post loading method which has value only 71%. Moreover, at the final time of drug dissolution test shows in situ loading method has value of 96% for total accumulative of drug dissolution, meanwhile post loading method has 72%. The value of drug dissolution test from both method is used for analyzing drug dissolution mechanism of amoxicillin trihydrate from hydrogel network with four mathematical drug mechanism models as parameter. The polymer network encounter destructive degradation causes by acid solution which used as dissolution medium, and the level of degradation is observed with optical microscope. However the result shows that degradation of the polymer network doesn't affect drug dissolution mechanism directly. Although the pore forming agent causes the pore inside the hydrogel network create interconnection and it was quite influential to drug dissolution mechanism. Interconnected pore is observed with Scanning Electron Microscope (SEM) and shows that the amount and area of interconnected pore inside the hydrogel network is increasing as drug dissolution goes on.
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Yue, Yiying; Han, Jingquan; Han, Guangping; French, Alfred D; Qi, Yadong; Wu, Qinglin
2016-08-20
Core-shell structured hydrogels consisting of a flexible interpenetrating polymer network (IPN) core and a rigid semi-IPN shell were prepared through chemical crosslinking of polyvinyl alcohol (PVA) and sodium alginate (SA) with Ca(2+) and glutaraldehyde. Short cellulose nanofibers (CNFs) extracted from energycane bagasse were incorporated in the hydrogel. The shell was micro-porous and the core was macro-porous. The hydrogels could be used in multiple adsorption-desorption cycles for dyes, and the maximum methyl blue adsorption capacity had a 10% increase after incorporating CNFs. The homogeneous distribution of CNFs in PVA-SA matrix generated additional hydrogen bonds among the polymer molecular chains, resulting in enhanced density, viscoelasticity, and mechanical strength for the hydrogel. Specifically, the compressive strength of the hydrogel reached 79.5kPa, 3.2 times higher than that of the neat hydrogel. Copyright © 2016 Elsevier Ltd. All rights reserved.
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NASA Astrophysics Data System (ADS)
Ojeda-Guillén, D.; Mota, R. D.; Granados, V. D.
2015-03-01
We show that the (2+1)-dimensional Dirac-Moshinsky oscillator coupled to an external magnetic field can be treated algebraically with the SU(1,1) group theory and its group basis. We use the su(1,1) irreducible representation theory to find the energy spectrum and the eigenfunctions. Also, with the su(1,1) group basis we construct the relativistic coherent states in a closed form for this problem. Supported by SNI-México, COFAA-IPN, EDI-IPN, EDD-IPN, SIP-IPN project number 20140598
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Ahmet M. Karaaslan; Mandla A. Tshabalala; Gisela Buschle-Diller
2010-01-01
The cell wall of most plant biomass from forest and agricultural resources consists of three major polymers, cellulose, hemicellulose, and lignin. Of these, hemicelluloses have gained increasing attention as sustainable raw materials. In this study, novel pH-sensitive semi-IPN hydrogels based on hemicelluloses and chitosan were prepared using glutaraldehyde as the...
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Neuropilin asymmetry mediates a left-right difference in habenular connectivity.
Kuan, Yung-Shu; Yu, Hung-Hsiang; Moens, Cecilia B; Halpern, Marnie E
2007-03-01
The medial habenular nuclei of the zebrafish diencephalon, which lie bilateral to the pineal complex, exhibit left-right differences in their neuroanatomy, gene expression profiles and axonal projections to the unpaired midbrain target--the interpeduncular nucleus (IPN). Efferents from the left habenula terminate along the entire dorsoventral extent of the IPN, whereas axons from the right habenula project only to the ventral IPN. How this left-right difference in connectivity is established and the factors involved in differential target recognition are unknown. Prior to IPN innervation, we find that only the left habenula expresses the zebrafish homologue of Neuropilin1a (Nrp1a), a receptor for class III Semaphorins (Sema3s). Directional asymmetry of nrp1a expression relies on Nodal signaling and the presence of the left-sided parapineal organ. Loss of Nrp1a, through parapineal ablation or depletion by antisense morpholinos, prevents left habenular neurons from projecting to the dorsal IPN. Selective depletion of Sema3D, but not of other Sema family members, similarly disrupts innervation of the dorsal IPN. Conversely, Sema3D overexpression results in left habenular projections that extend to the dorsal IPN, as well as beyond the target. The results indicate that Sema3D acts in concert with Nrp1a to guide neurons on the left side of the brain to innervate the target nucleus differently than those on the right side.
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ERIC Educational Resources Information Center
Blansdorf, Klaus, Ed.
The Institut fur die Padagogik der Naturwissenschaften (IPN) is the research institute for science education, with a national function in the Federal Republic of Germany. The IPN consists of biology education, chemistry education, physics education, educational science, research methodology/statistics, and administration/general services…
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A circuit-based mechanism underlying familiarity signaling and the preference for novelty
Molas, Susanna; Zhao-Shea, Rubing; Liu, Liwang; DeGroot, Steven R.; Gardner, Paul D.; Tapper, Andrew R.
2017-01-01
Novelty preference (NP) is an evolutionarily conserved, essential survival mechanism often dysregulated in neuropsychiatric disorders. NP is mediated by a motivational dopamine signal that increases in response to novel stimuli thereby driving exploration. However, the mechanism by which once novel stimuli transitions to familiar stimuli is unknown. Here we describe a neuroanatomical substrate for familiarity signaling, the interpeduncular nucleus (IPN) of the midbrain, which is activated as novel stimuli become familiar with multiple exposures. Optogenetic silencing of IPN neurons increases salience of and interaction with familiar stimuli without affecting novelty responses; whereas, photo-activation of the same neurons reduces exploration of novel stimuli mimicking familiarity. Bi-directional control of NP by the IPN depends on familiarity- and novelty-signals arising from excitatory habenula and dopaminergic ventral tegmental area inputs, which activate and reduce IPN activity, respectively. These results demonstrate that familiarity signals through unique IPN circuitry that opposes novelty seeking to control NP. PMID:28714952
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A circuit-based mechanism underlying familiarity signaling and the preference for novelty.
Molas, Susanna; Zhao-Shea, Rubing; Liu, Liwang; DeGroot, Steven R; Gardner, Paul D; Tapper, Andrew R
2017-09-01
Novelty preference (NP) is an evolutionarily conserved, essential survival mechanism often dysregulated in neuropsychiatric disorders. NP is mediated by a motivational dopamine signal that increases in response to novel stimuli, thereby driving exploration. However, the mechanism by which once-novel stimuli transition to familiar stimuli is unknown. Here we describe a neuroanatomical substrate for familiarity signaling, the interpeduncular nucleus (IPN) of the midbrain, which is activated as novel stimuli become familiar with multiple exposures. In mice, optogenetic silencing of IPN neurons increases salience of and interaction with familiar stimuli without affecting novelty responses, whereas photoactivation of the same neurons reduces exploration of novel stimuli mimicking familiarity. Bidirectional control of NP by the IPN depends on familiarity signals and novelty signals arising from excitatory habenula and dopaminergic ventral tegmentum inputs, which activate and reduce IPN activity, respectively. These results demonstrate that familiarity signals through unique IPN circuitry that opposes novelty seeking to control NP.
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Novel Hydrogels from Renewable Resources
NASA Astrophysics Data System (ADS)
Karaaslan, Muzafer Ahmet
2011-12-01
The cell wall of most plant biomass from forest and agricultural resources consists of three major polymers, cellulose, hemicellulose and lignin. Of these, hemicelluloses have gained increasing attention as sustainable raw materials. In the first part of this study, novel pH-sensitive semi-IPN hydrogels based on hemicelluloses and chitosan were prepared using glutaraldehyde as the crosslinking agent. The hemicellulose isolated from aspen was analyzed for sugar content by HPLC, and its molecular weight distribution was determined by high performance size exclusion chromatography. Results revealed that hemicellulose had a broad molecular weight distribution with a fair amount of polymeric units, together with xylose, arabinose and glucose. The effect of hemicellulose content on mechanical properties and swelling behavior of hydrogels were investigated. The semi-IPNs hydrogel structure was confirmed by FT-IR, X-ray study and ninhydrin assay method. X-ray analysis showed that higher hemicellulose contents yielded higher crystallinity. Mechanical properties were mainly dependent on the crosslink density and average molecular weight between crosslinks. Swelling ratios increased with increasing hemicellulose content and were high at low pH values due to repulsion between similarly charged groups. In vitro release study of a model drug showed that these semi-IPN hydrogels could be used for controlled drug delivery into gastric fluid. The aim of the second part of this study was to control the crosslink density and the mechanical properties of hemicellulose/chitosan semi-IPN hydrogels by changing the crosslinking sequence. It has been hypothesized that by performing the crosslinking step before introducing hemicellulose, covalent crosslinking of chitosan would not be hindered and therefore more and/or shorter crosslinks could be formed. Furthermore, additional secondary interactions and crystalline domains introduced through hemicellulose could be favorable in terms of mechanical stability of semi-IPN hydrogels. In this last section of this study, the natural affinity of hemicellulose to cellulose was utilized to coat cellulose whiskers with chemically modified hemicellulose isolated from wood fiber. Surface modified cellulose nanowhiskers were used to prepare nanocomposite hydrogels using free radical polymerization of 2-hydroxyethyl methacrylate (HEMA), a biocompatible monomer. The effect of morphology and concentration of the incorporated nanocrystals on the hydrogel network was related to the mechanical properties, viscoelastic behavior and swelling of the hydrogels.
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Standardised versus Individualised Parenteral Nutrition. Further Food for Thought.
McCarthy, R; Segurado, R; Crealey, M; Twomey, A
2016-04-11
Parenteral Nutrition may be prescribed as a standard PN (SPN) formulation or as an individualised PN (IPN) formulation. SPN may have advantages in terms of rapid availability, less prescription errors, decreased risk of infection and cost savings but IPN, specifically tailored to an infants needs, may achieve better outcomes in terms of nutrient intake and weight gain. The aim of our study was to determine if VLBW infants in our NICU benefited from receiving IPN over currently available SPN solutions. Our findings were that VLBW infants prescribed IPN received significantly more amino acid (28%), glucose (6%), energy (11%) and calcium (8%) from the aqueous phase of PN than had they received a similar volume of SPN. The benefits were seen over all the days for which PN was administered. In conclusion, IPN was found to offer significant benefits to our VLBW infants. Modifications to currently available SPN would result in better SPN formulations. Our study also supported the recent recommendation to reduce the calcium:phosphate ratio in PN solutions to avoid early hypophosphataemia.
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Zhao-Shea, Rubing; DeGroot, Steven R.; Liu, Liwang; Vallaster, Markus; Pang, Xueyan; Su, Qin; Gao, Guangping; Rando, Oliver J.; Martin, Gilles E.; George, Olivier; Gardner, Paul D.; Tapper, Andrew R.
2015-01-01
Increased anxiety is a predominant withdrawal symptom in abstinent smokers, yet the neuroanatomical and molecular bases underlying it are unclear. Here, we show that withdrawal-induced anxiety increases activity of neurons in the interpeduncular intermediate (IPI), a subregion of the interpeduncular nucleus (IPN). IPI activation during nicotine withdrawal was mediated by increased corticotropin releasing factor (CRF) receptor-1 expression and signaling, which modulated glutamatergic input from the medial habenula (MHb). Pharmacological blockade of IPN CRF1 receptors or optogenetic silencing of MHb input reduced IPI activation and alleviated withdrawal-induced anxiety; whereas IPN CRF infusion in mice increased anxiety. We identified a meso-interpeduncular circuit, consisting of ventral tegmental area (VTA) dopaminergic neurons projecting to the IPN, as a potential source of CRF. Knock-down of CRF synthesis in the VTA prevented IPI activation and anxiety during nicotine withdrawal. These data indicate that increased CRF receptor signaling within a VTA-IPN-MHb circuit triggers anxiety during nicotine withdrawal. PMID:25898242
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McLaughlin, Ian; Dani, John A; De Biasi, Mariella
2017-08-01
Abstinence from chronic use of addictive drugs triggers an aversive withdrawal syndrome that compels relapse and deters abstinence. Many features of this syndrome are common across multiple drugs, involving both affective and physical symptoms. Some of the network signaling underlying withdrawal symptoms overlaps with activity that is associated with aversive mood states, including anxiety and depression. Given these shared features, it is not surprising that a particular circuit, the dorsal diencephalic conduction system, and the medial habenula (MHb) and interpeduncular nucleus (IPN), in particular, have been identified as critical to the emergence of aversive states that arise both as a result and, independently, of drug addiction. As the features of this circuit continue to be characterized, the MHb-IPN axis is emerging as a viable target for therapeutics to aid in the treatment of addiction to multiple drugs of abuse as well as mood-associated disorders. This is an article for the special issue XVth International Symposium on Cholinergic Mechanisms. © 2017 International Society for Neurochemistry.
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NASA Technical Reports Server (NTRS)
1977-01-01
The facilities, programming system, and monitor and control system for the deep space network are described. Ongoing planetary and interplanetary flight projects are reviewed, along with tracking and ground-based navigation, communications, and network and facility engineering.
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Neuronal Correlates of Cross-Modal Transfer in the Cerebellum and Pontine Nuclei
Campolattaro, Matthew M.; Kashef, Alireza; Lee, Inah; Freeman, John H.
2011-01-01
Cross-modal transfer occurs when learning established with a stimulus from one sensory modality facilitates subsequent learning with a new stimulus from a different sensory modality. The current study examined neuronal correlates of cross-modal transfer of Pavlovian eyeblink conditioning in rats. Neuronal activity was recorded from tetrodes within the anterior interpositus nucleus (IPN) of the cerebellum and basilar pontine nucleus (PN) during different phases of training. After stimulus pre-exposure and unpaired training sessions with a tone conditioned stimulus (CS), light CS, and periorbital stimulation unconditioned stimulus (US), rats received associative training with one of the CSs and the US (CS1-US). Training then continued on the same day with the other CS to assess cross-modal transfer (CS2-US). The final training session included associative training with both CSs on separate trials to establish stronger cross-modal transfer (CS1/CS2). Neurons in the IPN and PN showed primarily unimodal responses during pre-training sessions. Learning-related facilitation of activity correlated with the conditioned response (CR) developed in the IPN and PN during CS1-US training. Subsequent CS2-US training resulted in acquisition of CRs and learning-related neuronal activity in the IPN but substantially less little learning-related activity in the PN. Additional CS1/CS2 training increased CRs and learning-related activity in the IPN and PN during CS2-US trials. The findings suggest that cross-modal neuronal plasticity in the PN is driven by excitatory feedback from the IPN to the PN. Interacting plasticity mechanisms in the IPN and PN may underlie behavioral cross-modal transfer in eyeblink conditioning. PMID:21411647
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Mouli, Venigalla Pratap; Sreenivas, Vishnubhatla; Garg, Pramod Kumar
2013-02-01
Conservative treatment (intensive care, a combination of antimicrobial agents, and nutritional support, with or without drainage of the infected fluid) has recently been shown to be effective for patients with infected pancreatic necrosis (IPN), but the data from individual studies are not robust enough to recommend it as the standard of care. We performed a systematic review and meta-analysis of studies related to primary conservative management for IPN. We performed a literature search of MEDLINE/PubMed from January 1990 to March 2012 for studies of a priori protocols for primary conservative treatment, without necrosectomy, for consecutive patients with IPN. We analyzed data from 8 studies, comprising 324 patients with IPN who received primary conservative management. We then analyzed an additional 4 studies (comprising 157 patients) that reported the efficacy of percutaneous drainage in nonconsecutive patients with IPN. Outcome measures were the success of conservative management strategy, need for necrosectomy, and mortality. There was significant heterogeneity in results among the studies. Based on a random effects model, conservative management was successful for 64% of patients (95% confidence interval [CI], 51%-78%); mortality was 12% (95% CI, 6%-18%), and 26% of patients required necrosectomy or additional surgery for complications (95% CI, 15%-37%). A separate analysis of 4 studies that reported outcomes of nonconsecutive patients with IPN following percutaneous drainage had comparable results; 50% had successful outcomes (95% CI, 43%-58%), mortality was 18% (95% CI, 6%-30%), and 38% of patients required surgery (95% CI, 20%-56%). Conservative management without necrosectomy is a successful approach for 64% of patients with IPN. This approach has low mortality and prevents surgical necrosectomy. Copyright © 2013 AGA Institute. Published by Elsevier Inc. All rights reserved.
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Preliminary performance analysis of an interplanetary navigation system using asteroid based beacons
NASA Technical Reports Server (NTRS)
Jee, J. Rodney; Khatib, Ahmad R.; Muellerschoen, Ronald J.; Williams, Bobby G.; Vincent, Mark A.
1988-01-01
A futuristic interplanetary navigation system using transmitters placed on selected asteroids is introduced. This network of space beacons is seen as a needed alternative to the overly burdened Deep Space Network. Covariance analyses on the potential performance of these space beacons located on a candidate constellation of eight real asteroids are initiated. Simplified analytic calculations are performed to determine limiting accuracies attainable with the network for geometric positioning. More sophisticated computer simulations are also performed to determine potential accuracies using long arcs of range and Doppler data from the beacons. The results from these computations show promise for this navigation system.
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Spin Number Coherent States and the Problem of Two Coupled Oscillators
NASA Astrophysics Data System (ADS)
Ojeda-Guillén, D.; Mota, R. D.; Granados, V. D.
2015-07-01
From the definition of the standard Perelomov coherent states we introduce the Perelomov number coherent states for any su(2) Lie algebra. With the displacement operator we apply a similarity transformation to the su(2) generators and construct a new set of operators which also close the su(2) Lie algebra, being the Perelomov number coherent states the new basis for its unitary irreducible representation. We apply our results to obtain the energy spectrum, the eigenstates and the partition function of two coupled oscillators. We show that the eigenstates of two coupled oscillators are the SU(2) Perelomov number coherent states of the two-dimensional harmonic oscillator with an appropriate choice of the coherent state parameters. Supported by SNI-México, COFAA-IPN, EDD-IPN, EDI-IPN, SIP-IPN Project No. 20150935
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Reszetow, Jacek; Hać, Stanisław; Dobrowolski, Sebastian; Stefaniak, Tomasz; Wajda, Zdzisław; Gruca, Zbigniew; Sledziński, Zbigniew; Studniarek, Michał
2007-10-01
Infected pancreatic necrosis (IPN) is a serious complication of acute pancreatitis. Data concerning survivors' quality of life and pancreatic functions are scarce. Follow-up of the patients with alcohol and biliary etiology of IPN treated with open necrosectomy was performed. Twenty-eight survivors after operative treatment (Bradley procedure) of IPN were followed up 24 to 96 months after discharge from the hospital (10 biliary and 18 alcohol patients). Their exocrine and endocrine pancreatic functions and quality of life (Functional Assessment of Chronic Illness Therapy scale) were evaluated. Pancreatic tissue remaining after necrosectomy was visualized by use of contrast-enhanced computed tomography (CT). In 44.4% of alcohol-induced IPN patients, the presence of the whole pancreas was shown on the follow-up CT, contrary to the biliary group, where the partial lack of the pancreas was observed in all cases. Pancreatic tissue calcifications were present on CT in 8 patients of alcohol-induced acute pancreatitis group only. Median stool elastase 1 concentrations were 318.1 U/mL in the biliary group and 238.3 U/mL in the alcohol-induced group (not significant). The Functional Assessment of Chronic Illness Therapy scale showed significantly higher social/family and emotional well-being in patients with biliary acute necrotizing pancreatitis. Patients after alcohol-induced IPN had lower quality of life compared with biliary etiology. Biliary and alcohol-induced IPN patients after surgical treatment have nonsignificant differences of endocrine and exocrine pancreatic functions.
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Toughening of PMR composites by semi-interpenetrating networks
NASA Technical Reports Server (NTRS)
Tiwari, S. N.; Srinivansan, K.
1991-01-01
Polymerization of monomer reactants (PMR-15) type polyimide and RP46 prepregs were drum wound using IM-7 fibers. Prepregging and processing conditions were optimized to yield good quality laminates with fiber volume fractions of 60 percent (+/- 2 percent). Samples were fabricated and tested to determine comprehensive engineering properties of both systems. These included 0 deg flexure, short beam shear, transverse flexure and tension, 0 deg tension and compression, intralaminar shear, short block compression, mode 1 and 2 fracture toughness, and compression after impact properties. Semi-2-IPN (interpenetrating polymer networks) toughened PMR-15 and RP46 laminates were also fabricated and tested for the same properties.
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NASA Astrophysics Data System (ADS)
Dagousset, Laure; Pognon, Grégory; Nguyen, Giao T. M.; Vidal, Frédéric; Jus, Sébastien; Aubert, Pierre-Henri
2018-07-01
Electrochemical energy storage is a very active research topic. However, the use of liquid electrolyte in such systems as supercacitors presents several drawbacks on security and packaging. One way to overcome these issues is to design supercapacitors using solid-state electrolytes. We report here the one-pot synthesis and the characterization of self-standing gel polymer electrolyte (SGPE) composed of semi-Interpenetrating Polymer Networks (semi-IPN) based on poly(ethylene oxide) (PEO) network and non cross-linked nitrile butadiene rubber (NBR), self-containing EMITFSI/γ-Butyrolactone (50/50 wt%/wt%) binary mixtures. The SGPE under the form of a thin film are then used as solid electrolyte and also as separator in supercapacitors with Single Wall Carbon Nanotubes (SWCNTs) bucky paper as electrodes. Thermal characterization revealed the suitability of all synthesized membrane in wide range of operating temperature. Electrochemical stabilities of SGPE were close to that of a cellulose separator system (ESW∼3.2-3.6 V) at 20 °C, and were relatively higher than a cellulose system at 100 °C: 2.1-2.5 V and 1.8 V respectively. Furthermore, floating experiments at 100 °C (holding voltage at 2 V) revealed the exceptionally high stability of SGPE, with a residual capacitance of 93% after 500 h. This high electrochemical performance demonstrated the potential of semi-IPN SGPE as separator/electrolyte for high performance supercapacitors.
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DOE Office of Scientific and Technical Information (OSTI.GOV)
Yu, Miao, E-mail: yumiao@cqu.edu.cn; Qi, Song; Fu, Jie
A high-damping magnetorheological elastomer (MRE) with bi-directional magnetic-control modulus is developed. This MRE was synthesized by filling NdFeB particles into polyurethane (PU)/ epoxy (EP) interpenetrating network (IPN) structure. The anisotropic samples were prepared in a permanent magnetic field and magnetized in an electromagnetic field of 1 T. Dynamic mechanical responses of the MRE to applied magnetic fields are investigated through magneto-rheometer, and morphology of MREs is observed via scanning electron microscope (SEM). Test result indicates that when the test field orientation is parallel to that of the sample's magnetization, the shear modulus of sample increases. On the other hand, when themore » orientation is opposite to that of the sample's magnetization, shear modulus decreases. In addition, this PU/EP IPN matrix based MRE has a high-damping property, with high loss factor and can be controlled by applying magnetic field. It is expected that the high damping property and the ability of bi-directional magnetic-control modulus of this MRE offer promising advantages in seismologic application.« less
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Brown, Christina D; Neidig, Michael L; Neibergall, Matthew B; Lipscomb, John D; Solomon, Edward I
2007-06-13
Isopenicillin N synthase (IPNS) is a unique mononuclear nonheme Fe enzyme that catalyzes the four-electron oxidative double ring closure of its substrate ACV. A combination of spectroscopic techniques including EPR, absorbance, circular dichroism (CD), magnetic CD, and variable-temperature, variable-field MCD (VTVH-MCD) were used to evaluate the geometric and electronic structure of the [FeNO]7 complex of IPNS coordinated with the ACV thiolate ligand. Density Function Theory (DFT) calculations correlated to the spectroscopic data were used to generate an experimentally calibrated bonding description of the Fe-IPNS-ACV-NO complex. New spectroscopic features introduced by the binding of the ACV thiolate at 13 100 and 19 800 cm-1 are assigned as the NO pi*(ip) --> Fe dx2-y2 and S pi--> Fe dx2-y2 charge transfer (CT) transitions, respectively. Configuration interaction mixes S CT character into the NO pi*(ip) --> Fe dx2-y2 CT transition, which is observed experimentally from the VTVH-MCD data from this transition. Calculations on the hypothetical {FeO2}8 complex of Fe-IPNS-ACV reveal that the configuration interaction present in the [FeNO]7 complex results in an unoccupied frontier molecular orbital (FMO) with correct orientation and distal O character for H-atom abstraction from the ACV substrate. The energetics of NO/O2 binding to Fe-IPNS-ACV were evaluated and demonstrate that charge donation from the ACV thiolate ligand renders the formation of the FeIII-superoxide complex energetically favorable, driving the reaction at the Fe center. This single center reaction allows IPNS to avoid the O2 bridged binding generally invoked in other nonheme Fe enzymes that leads to oxygen insertion (i.e., oxygenase function) and determines the oxidase activity of IPNS.
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Hip and knee effects after implantation of a drop foot stimulator.
Yao, Daiwei; Lahner, Matthias; Jakubowitz, Eike; Thomann, Anna; Ettinger, Sarah; Noll, Yvonne; Stukenborg-Colsman, Christina; Daniilidis, Kiriakos
2017-01-01
An active ankle dorsiflexion is essential for a proper gait pattern. If there is a failure of the foot lifting, considerable impairments occur. The therapeutic effect of an implantable peroneus nerve stimulator (iPNS) for the ankle dorsiflexion is already approved by recent studies. However, possible affection for knee and hip motion after implantation of an iPNS is not well described. The objective of this retrospective study was to examine with a patient cohort whether the use of iPNS induces a lower-extremity flexion withdrawal response in the form of an increased knee and hip flexion during swing phase. Eighteen subjects (12 m/6 w) treated with an iPNS (ActiGait®, Otto Bock, Duderstadt, Germany) were examined in knee and hip motion by gait analysis with motion capture system (Vicon Motion System Ltd®, Oxford, UK) and Plug-in-Gait model after a mean follow up from 12.5 months. The data were evaluated and compared in activated and deactivated iPNS. Only little changes could be documented, as a slight average improvement in peak knee flexion during stand phase from 1.0° to 2.5° and peak hip flexion in stance from 3.1° to 2.1° In contrast, peak knee flexion during swing appeared similar (25.3° to 25.7°) same as peak hip flexion during swing. In comparison with the healthy extremity, a more symmetric course of the knee flexion during stand phase could be shown. No statistical significant improvements or changes in hip and knee joint could be shown in this study. Only a more symmetric knee flexion during stand phase and a less hip flexion during stand phase might be hints for a positive affection of iPNS for knee and hip joint. It seems that the positive effect of iPNS is only based on the improvement in ankle dorsiflexion according to the recent literature.
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Characterization of konjac glucomannan-gelatin IPN physical hydrogel scaffold
NASA Astrophysics Data System (ADS)
Chen, Xiliang; Chen, Qinghua; Yan, Tingting; Liu, Jinkun
2017-06-01
A novel IPN hydrogel scaffold is prepared by freeze-drying method, in which konjac galactomannan (KGM) and gelatin are physically crosslinked respectively. This scaffold is thermostable, and the structure of this scaffold is analysed by scanning electron microscope, Fourier transform infrared spectrum, and X-ray diffraction method. The FT-IR results show that hydrogen bonds are formed between KGM and gelatin molecules, which hinder the formation of their respective crosslinking. This is consistent with the XRD results that the crystallinity gets lower in the IPN gels compared with pure gelatin and KGM gels. The morphologies of freeze-dried hydrogels are observed by SEM and the mechanical properties of the scaffolds are tested to analyse the relationship between the structures and properties. Although this novel IPN hydrogel is physical gel, it shows rubber-like performance as chemical gels. And it is nontoxic, so it can be used as the scaffold for cartilage tissue engineering that embedded in human bodies.
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Khan, Aftab A; Al-Kheraif, Abdulaziz A; Al-Shehri, Abdullah M; Säilynoja, Eija; Vallittu, Pekka K
2018-02-01
This laboratory study was aimed to characterize semi-interpenetrating polymer network (semi-IPN) of fiber-reinforced composite (FRC) prepregs that had been stored for up to two years before curing. Resin impregnated prepregs of everStick C&B (StickTech-GC, Turku, Finland) glass FRC were stored at 4°C for various lengths of time, i.e., two-weeks, 6-months and 2-years. Five samples from each time group were prepared with a light initiated free radical polymerization method, which were embedded to its long axis in self-curing acrylic. The nanoindentation readings on the top surface toward the core of the sample were made for five test groups, which were named as "stage 1-5". To evaluate the nanohardness and modulus of elasticity of the polymer matrix, a total of 4 slices (100µm each) were cut from stage 1 to stage 5. Differences in nanohardness values were evaluated with analysis of variance (ANOVA), and regression model was used to develop contributing effect of the material's different stages to the total variability in the nanomechanical properties. Additional chemical and thermal characterization of the polymer matrix structure of FRC was carried out. It was hypothesized that time of storage may have an influence on the semi-IPN polymer structure of the cured FRC. The two-way ANOVA test revealed that the storage time had no significant effect on the nanohardness of FRC (p = 0.374). However, a highly significant difference in nanohardness values was observed between the different stages of FRC (P<0.001). The regression coefficient suggests nanohardness increased on average by 0.039GPa for every storage group. The increased nanohardness values in the core region of 6-months and 2-years stored prepregs might be due to phase-segregation of components of semi-IPN structure of FRC prepregs before their use. This may have an influence to the surface bonding properties of the cured FRC. Copyright © 2017 Elsevier Ltd. All rights reserved.
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The scheduling of tracking times for interplanetary spacecraft on the Deep Space Network
NASA Technical Reports Server (NTRS)
Webb, W. A.
1978-01-01
The Deep Space Network (DSN) is a network of tracking stations, located throughout the globe, used to track spacecraft for NASA's interplanetary missions. This paper describes a computer program, DSNTRAK, which provides an optimum daily tracking schedule for the DSN given the view periods at each station for a mission set of n spacecraft, where n is between 2 and 6. The objective function is specified in terms of relative total daily tracking time requirements between the n spacecraft. Linear programming is used to maximize the total daily tracking time and determine an optimal daily tracking schedule consistent with DSN station capabilities. DSNTRAK is used as part of a procedure to provide DSN load forecasting information for proposed future NASA mission sets.
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Thermally activated delayed fluorescence organic dots for two-photon fluorescence lifetime imaging
NASA Astrophysics Data System (ADS)
He, Tingchao; Ren, Can; Li, Zhuohua; Xiao, Shuyu; Li, Junzi; Lin, Xiaodong; Ye, Chuanxiang; Zhang, Junmin; Guo, Lihong; Hu, Wenbo; Chen, Rui
2018-05-01
Autofluorescence is a major challenge in complex tissue imaging when molecules present in the biological tissue compete with the fluorophore. This issue may be resolved by designing organic molecules with long fluorescence lifetimes. The present work reports the two-photon absorption (TPA) properties of a thermally activated delayed fluorescence (TADF) molecule with carbazole as the electron donor and dicyanobenzene as the electron acceptor (i.e., 4CzIPN). The results indicate that 4CzIPN exhibits a moderate TPA cross-section (˜9 × 10-50 cm4 s photon-1), high fluorescence quantum yield, and a long fluorescence lifetime (˜1.47 μs). 4CzIPN was compactly encapsulated into an amphiphilic copolymer via nanoprecipitation to achieve water-soluble organic dots. Interestingly, 4CzIPN organic dots have been utilized in applications involving two-photon fluorescence lifetime imaging (FLIM). Our work aptly demonstrates that TADF molecules are promising candidates of nonlinear optical probes for developing next-generation multiphoton FLIM applications.
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Fabrication of tough epoxy with shape memory effects by UV-assisted direct-ink write printing.
Chen, Kaijuan; Kuang, Xiao; Li, Vincent; Kang, Guozheng; Qi, H Jerry
2018-03-07
3D printing of epoxy-based shape memory polymers with high mechanical strength, excellent thermal stability and chemical resistance is highly desirable for practical applications. However, thermally cured epoxy in general is difficult to print directly. There have been limited numbers of successes in printing epoxy but they suffer from relatively poor mechanical properties. Here, we present an ultraviolet (UV)-assisted 3D printing of thermally cured epoxy composites with high tensile toughness via a two-stage curing approach. The ink containing UV curable resin and epoxy oligomer is used for UV-assisted direct-ink write (DIW)-based 3D printing followed by thermal curing of the part containing the epoxy oligomer. The UV curable resin forms a network by photo polymerization after the 1st stage of UV curing, which can maintain the printed architecture at an elevated temperature. The 2nd stage thermal curing of the epoxy oligomer yields an interpenetrating polymer network (IPN) composite with highly enhanced mechanical properties. It is found that the printed IPN epoxy composites enabled by the two-stage curing show isotropic mechanical properties and high tensile toughness. We demonstrated that the 3D-printed high-toughness epoxy composites show good shape memory properties. This UV-assisted DIW 3D printing via a two-stage curing method can broaden the application of 3D printing to fabricate thermoset materials with enhanced tensile toughness and tunable properties for high-performance and functional applications.
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Upadhyay, Mansi; Adena, Sandeep Kumar Reddy; Vardhan, Harsh; Yadav, Sarita K; Mishra, Brahmeshwar
2018-04-27
The research aims the development and optimization of capecitabine loaded interpenetrating polymeric network by ionotropic gelation method using polymers locust bean gum and sodium alginate by QbD approach. FMEA was performed to recognize the risks influencing CQAs. BBD was applied to study the effect of factors (polymer ratio, amount of cross-linker and curing time) on responses (particle size, % drug entrapment and % drug release). Polynomial equations and 3-D graphs were plotted to relate between factors and responses. The results of the optimized batch viz. particle size (457.92 ± 1.6 μm), % drug entrapment (74.11 ± 3.1%) and % drug release (90.23 ± 2.1%) were close to the predicted values generated by Minitab® 17. Characterization techniques SEM, EDX, FTIR, DSC and XRD were also performed for the optimized batch. To study the water transport inside IPN microbeads, swelling study was done. In vitro drug release of optimized batch showed controlled drug release for 12 h. Pharmacokinetic study carried out following oral administration in Albino Wistar rats exhibited that optimized microbeads had better PK parameters than free drug. In vitro cytotoxicity against HT-29 cells revealed significant reduction of the cell growth when treated with optimized formulation indicating IPN microbeads as effective dosage form for treating colon cancer. Copyright © 2018. Published by Elsevier B.V.
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A second catalog of gamma ray bursts: 1978 - 1980 localizations from the interplanetary network
NASA Technical Reports Server (NTRS)
Atteia, J. L.; Barat, C.; Hurley, K.; Niel, M.; Vedrenne, G.; Evans, W. D.; Fenimore, E. E.; Klebesadel, R. W.; Laros, J. G.; Cline, T. L.
1985-01-01
Eighty-two gamma ray bursts were detected between 1978 September 14 and 1980 February 13 by the experiments of the interplanetary network (Prognoz 7, Venera 11 and 12 SIGNE experiments, Pioneer Venus Orbiter, International Sun-Earth Explorer 3, Helios 2, and Vela). Sixty-five of these events have been localized to annuli or error boxes by the method of arrival time analysis. The distribution of sources is consistent with isotropy, and there is no statistically convincing evidence for the detection of more than one burst from any source position. The localizations are compared with those of two previous catalogs.
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The Interplanetary Overlay Networking Protocol Accelerator
NASA Technical Reports Server (NTRS)
Pang, Jackson; Torgerson, Jordan L.; Clare, Loren P.
2008-01-01
A document describes the Interplanetary Overlay Networking Protocol Accelerator (IONAC) an electronic apparatus, now under development, for relaying data at high rates in spacecraft and interplanetary radio-communication systems utilizing a delay-tolerant networking protocol. The protocol includes provisions for transmission and reception of data in bundles (essentially, messages), transfer of custody of a bundle to a recipient relay station at each step of a relay, and return receipts. Because of limitations on energy resources available for such relays, data rates attainable in a conventional software implementation of the protocol are lower than those needed, at any given reasonable energy-consumption rate. Therefore, a main goal in developing the IONAC is to reduce the energy consumption by an order of magnitude and the data-throughput capability by two orders of magnitude. The IONAC prototype is a field-programmable gate array that serves as a reconfigurable hybrid (hardware/ firmware) system for implementation of the protocol. The prototype can decode 108,000 bundles per second and encode 100,000 bundles per second. It includes a bundle-cache static randomaccess memory that enables maintenance of a throughput of 2.7Gb/s, and an Ethernet convergence layer that supports a duplex throughput of 1Gb/s.
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Bundle Security Protocol for ION
NASA Technical Reports Server (NTRS)
Burleigh, Scott C.; Birrane, Edward J.; Krupiarz, Christopher
2011-01-01
This software implements bundle authentication, conforming to the Delay-Tolerant Networking (DTN) Internet Draft on Bundle Security Protocol (BSP), for the Interplanetary Overlay Network (ION) implementation of DTN. This is the only implementation of BSP that is integrated with ION.
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Intense Pulsed Neutron Source: Progress report 1991--1996. 15. Anniversary edition -- Volume 2
DOE Office of Scientific and Technical Information (OSTI.GOV)
NONE
1996-05-01
The 15th Anniversary Edition of the IPNS Progress Report is being published in recognition of the Intense Pulsed Neutron Source`s first 15 years of successful operation as a user facility. To emphasize the importance of this milestone, the author shave made the design and organization of the report significantly different from previous IPNS Progress Reports. This report consists of two volumes. For Volume 1, authors were asked to prepare articles that highlighted recent scientific accomplishments at IPNS, from 1991 to present; to focus on and illustrate the scientific advances achieved through the unique capabilities of neutron studies performed by IPNSmore » users; to report on specific activities or results from an instrument; or to focus on a body of work encompassing different neutron-scattering techniques. Articles were also included on the accelerator system, instrumentation, computing, target, and moderators. A list of published and ``in press` articles in journals, books, and conference proceedings, resulting from work done at IPNS since 1991, was compiled. This list is arranged alphabetically according to first author. Publication references in the articles are listed by last name of first author and year of publication. The IPNS experimental reports received since 1991 are compiled in Volume 2. Experimental reports referenced in the articles are listed by last name of first author, instrument designation, and experiment number.« less
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Tey, S; Ahmad-Annuar, A; Drew, A P; Shahrizaila, N; Nicholson, G A; Kennerson, M L
2016-08-01
The cytoplasmic dynein-dynactin genes are attractive candidates for neurodegenerative disorders given their functional role in retrograde transport along neurons. The cytoplasmic dynein heavy chain (DYNC1H1) gene has been implicated in various neurodegenerative disorders, and dynactin 1 (DCTN1) genes have been implicated in a wide spectrum of disorders including motor neuron disease, Parkinson's disease, spinobulbar muscular atrophy and hereditary spastic paraplegia. However, the involvement of other dynactin genes with inherited peripheral neuropathies (IPN) namely, hereditary sensory neuropathy, hereditary motor neuropathy and Charcot-Marie-Tooth disease is under reported. We screened eight genes; DCTN1-6 and ACTR1A and ACTR1B in 136 IPN patients using whole-exome sequencing and high-resolution melt (HRM) analysis. Eight non-synonymous variants (including one novel variant) and three synonymous variants were identified. Four variants have been reported previously in other studies, however segregation analysis within family members excluded them from causing IPN in these families. No variants of disease significance were identified in this study suggesting the dynactin genes are unlikely to be a common cause of IPNs. However, with the ease of querying gene variants from exome data, these genes remain worthwhile candidates to assess unsolved IPN families for variants that may affect the function of the proteins. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
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Intense Pulsed Neutron Source: Progress report 1991--1996. 15. Anniversary edition -- Volume 1
DOE Office of Scientific and Technical Information (OSTI.GOV)
Marzec, B.
1996-05-01
The 15th Anniversary Edition of the IPNS Progress Report is being published in recognition of the Intense Pulsed Neutron Source`s first 15 years of successful operation as a user facility. To emphasize the importance of this milestone, the authors have made the design and organization of the report significantly different from previous IPNS Progress Reports. This report consists of two volumes. For Volume 1, authors were asked to prepare articles that highlighted recent scientific accomplishments at IPNS, from 1991 to present; to focus on and illustrate the scientific advances achieved through the unique capabilities of neutron studies performed by IPNSmore » users; to report on specific activities or results from an instrument; or to focus on a body of work encompassing different neutron-scattering techniques. Articles were also included on the accelerator system, instrumentation, computing, target, and moderators. A list of published and ``in press` articles in journals, books, and conference proceedings, resulting from work done at IPNS since 1991, was compiled. This list is arranged alphabetically according to first author. Publication references in the articles are listed by last name of first author and year of publication. The IPNS experimental reports received since 1991 are compiled in Volume 2. Experimental reports referenced in the articles are listed by last name of first author, instrument designation, and experiment number.« less
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The Spanish Fireball Network: Popularizing Interplanetary Matter
NASA Astrophysics Data System (ADS)
Trigo-Rodríguez, J. M.; Castro-Tirado, A.; Llorca, J.; Fabregat, J.
In order to increase in Spain the social interest in the study of interplanetary matter (asteroids, comets and meteoroids) we created the Spanish Photographic Meteor Network (SPMN) in 1997. This network has been dedicated to studying interplanetary matter with participation of researchers from three universities (Universitat Jaume I, Universitat de Barcelona and Universitat de València), the Institut d'Estudis Espacials de Catalunya (IEEC) and the Instituto de Astrofísica de Andalucía and it is also supported by the Atmospheric Sounding Station at El Arenosillo (INTA-CEDEA) and by the Experimental Station La Mayora (EELM-CSIC). In order to promote the participation of amateurs, our homepage (www.spmn.uji.es) presents public information about our research explains how amateur astronomers can participate in our network. In this paper we give some examples of the social role of a Fireball Network in order to give a coherent explanation to bright fireball events. Moreover, we also discuss the role of this kind of research project as a promoter of amateur participation and contribution to science. In fact, meteor astronomy can become an excellent area to form young researchers because systematic observation of meteors using photographic, video and CCD techniques has become one of the rare fields in astronomy in which amateurs can work together with professionals to make important contributions. We present here some results of the campaigns realized from the formation of the network. Finally, in a new step of development of our network, the all-sky CCD automatic cameras will be continuously detecting meteors and fireballs from four stations located in the Andalusia and Valencian communities by the end of 2005. Additionally, during important meteor showers we plan to develop fireball spectroscopy using medium field lenses.
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Electroactive polymer gels based on epoxy resin
NASA Astrophysics Data System (ADS)
Samui, A. B.; Jayakumar, S.; Jayalakshmi, C. G.; Pandey, K.; Sivaraman, P.
2007-04-01
Five types of epoxy gels have been synthesized from common epoxy resins and hardeners. Fumed silica and nanoclay, respectively, were used as fillers and butyl methacrylate/acrylamide were used as monomer(s) for making interpenetrating polymer networks (IPNs) in three compositions. Swelling study, tensile property evaluation, dynamic mechanical thermal analysis, thermo-gravimetric analysis, scanning electron microscopy and electroactive property evaluation were done. The gels have sufficient mechanical strength and the time taken for bending to 20° was found to be 22 min for forward bias whereas it was just 12 min for reverse bias.
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NASA Astrophysics Data System (ADS)
2011-09-01
AbeTakashiUniversity of Tokyotabe@nt.phys.s.u-tokyo.ac.jp AmusiaMironRacah Institute of Physics, Jerusalemamusia@vms.huji.ac.il BaldoMarcelloINFN Cataniabaldo@ct.infn.it BansalManiePanjab University, Chandigarhbansalmanni@gmail.com BarrancoFranciscoUniversity of Sevillebarranco@us.es BertschGeorgeUniversity of Washington, Seattlebertsch@u.washington.edu BhagwatAmeeyaCBS Mumbaiameeya@kth.se BorderieBernardIPN Orsayborderie@ipno.in2p3.fr CarbonellJaumeLPSC Grenoblejaume.carbonell@lpsc.in2p3.fr CarlsonJoeLos Alamos National Laboratorycarlson@lanl.gov ColòGianlucaINFN - Università degli Studi di Milanocolo@mi.infn.it DanielewiczPawelNSCL, Michigan State Universitydanielewicz@nscl.msu.edu DescouvemontPierreUniversité Libre de Bruxellespdesc@ulb.ac.be Dohet-EralyJérémyUniversité Libre de Bruxellesjdoheter@ulb.ac.be DraayerJerryLouisiana State Universitydraayer@lsu.edu DufourMarianneIPHC, Université de Strasbourgmarianne.dufour@ires.in2p3.fr DuguetThomasCEA Saclaythomas.duguet@cea.fr DukelskyJorgeCSIC Madriddukelsky@iem.cfmac.csic.es EbranJean-PaulCEA-DAM, Arpajonebran@ipno.in2p3.fr FreerMartinUniversity of Birminghamm.freer@bham.ac.uk FujiiShinichiroUniversity of Tokyosfujii@cns.s.u-tokyo.ac.jp FunakiYasuroRIKEN Nishina Center, Wakofunaki@riken.jp GrassoMarcellaIPN Orsaygrasso@ipno.in2p3.fr HaginoKouichiTohoku Universityhagino@nucl.phys.tohoku.ac.jp HansenHubertUniversité Claude Bernard Lyon 1hansen@ipnl.in2p3.fr HolzmannMarkusLPMMC Grenoblemarkus@lptl.jussieu.fr HoriuchiHisashiRCNP, Osaka Universityhoriuchi@rcnp.osaka-u.ac.jp HoriuchiWataruGSI Darmstadtw.horiuchi@gsi.de HupinGuillaumeGANIL, Caenhupin@ganil.fr JinMengHuazhong Normal University, Wuhanjinm@iopp.ccnu.edu.cn KamimuraMasayasuRIKEN Nishina Center, Wakomkamimura@riken.jp Kanada-En'yoYoshikoKyoto Universityyenyo@ruby.scphys.kyoto-u.ac.jp KatoKiyoshiHokkaido University, Sapporokato@nucl.sci.hokudai.ac.jp KawabataTakahiroKyoto Universitykawabata@scphys.kyoto-u.ac.jp KhanEliasIPN Orsaykhan@ipno.in2p3.fr KhodelVictorKurchatov Institute, Moscowvak@wuphys.wustl.edu KimuraMasaakiHokkaido University, Sapporomasaaki@nucl.sci.hokudai.ac.jp LacroixDenisGANIL, Caenlacroix@ganil.fr LiangHaozhaoPeking University, Beijinghzliang@pku.edu.cn MargueronJérômeIPN Orsayjerome.margueron@ipno.in2p3.fr MassotElisabethIPN Orsaymassot@ipno.in2p3.fr MengJiePeking University, Beijingmengj@pku.edu.cn MillerTomaszWarsaw University of Technologymillert@student.mini.pw.edu.pl MoghrabiKassemIPN Orsaymoghrabi@ipno.in2p3.fr NapolitaniPaoloIPN Orsaynapolita@ipno.in2p3.fr NeffThomasGSI Darmstadtt.neff@gsi.de NguyenVan GiaiIPN Orsaynguyen@ipno.in2p3.fr OtsukaTakaharuUniversity of Tokyootsuka@phys.s.u-tokyo.ac.jp PilletNathalie-MarieCEA-DAM, Arpajonnathalie.pillet@cea.fr QiChongKTH Stockholmchongq@kth.se RamananSunethraICTP Triestesramanan@ictp.it RingPeterTU Munichring@ph.tum.de Rios HuguetArnauUniversity of Surreya.rios@surrey.ac.uk RivetMarie-FranceIPN Orsayrivet@ipno.in2p3.fr RobledoLuisUniversidad Autonoma de Madridluis.robledo@uam.es Roca MazaXavierINFN Milanoxavier.roca.maza@mi.infn.it RöpkeGerdRostock Universitygerd.roepke@uni-rostock.de RowleyNeilIPN Orsayrowley@ipno.in2p3.fr SagawaHiroyukiUniversity of Aizusagawa@u-aizu.ac.jp SandulescuNicolaeIFIN-HH, Bucharestsandulescu@theory.nipne.ro SchuckPeterIPN Orsayschuck@ipno.in2p3.fr SedrakianArmenGoethe Universität Frankfurtsedrakian@th.physik.uni-frankfurt.de SeveryukhinAlexeyJINR Dubnasever@theor.jinr.ru SogoTakaakiIPN Orsaysogo@ipno.in2p3.fr SomàVittorioCEA Saclayvittorio.soma@cea.fr StrinatiGiancarloUniversità di Camerinogiancarlo.strinati@gmail.com SuharaTadahiroKyoto Universitysuhara@ruby.scphys.kyoto-u.ac.jp SukhoruchkinSergeiPetersburg Nuclear Physics Institutesergeis@pnpi.spb.ru SuzukiToruTokyo Metropolitan Universitysuzukitr@tmu.ac.jp SuzukiToshioNihon University, Tokyosuzuki@chs.nihon-u.ac.jp TarpanovDimitarINRNE, Sofiadimitert@yahoo.co.uk Tohsaki-SuzukiAkihiroOsaka Universitytohsaki@rcnp.osaka-u.ac.jp TypelStefanGSI Darmstadts.typel@gsi.de UesakaTomohiroUniversity of Tokyouesaka@cns.s.u-tokyo.ac.jp UrbanMichaelIPN Orsayurban@ipno.in2p3.fr Van IsackerPietGANIL Caenisacker@ganil.fr VigezziEnricoINFN Milanovigezzi@mi.infn.it ViñasXavierUniversitat de Barcelonaxavier@ecm.ub.es Vinh MauNicoleIPN Orsayvinhmau@ipno.in2p3.fr VitturiAndreaINFN Padovavitturi@pd.infn.it Von OertzenWolframHelmholtz Zentrum Berlinoertzen@helmholtz-berlin.de WambachJochenTechnische Universität Darmstadtjochen.wambach@physik.tu-darmstadt.de WlazłowskiGabrielWarsaw University of Technologygabrielw@if.pw.edu.pl YamadaTaiichiKanto Gakuin University, Yokohamayamada@kanto-gakuin.ac.jp YoshidaKenichiRIKEN Nishina Center, Wakokenichi.yoshida@riken.jp YoshidaSatoshiHosei University, Tokyos_yoshi@i.hosei.ac.jp
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NASA Technical Reports Server (NTRS)
Ng, C. K.
1986-01-01
The purpose is to provide an overview of the contributions presented in sessions SH3, SH1.5, SH4.6 and SH4.7 of the 19th International Cosmic Ray Conference. These contributed papers indicate that steady progress continues to be made in both the observational and the theoretical aspects of the transport and acceleration of energetic charged particles in the heliosphere. Studies of solar and interplanetary particles have placed emphasis on particle directional distributions in relation to pitch-angle scattering and magnetic focusing, on the rigidity and spatial dependence of the mean free path, and on new propagation regimes in the inner and outer heliosphere. Coronal propagation appears in need of correlative multi-spacecraft studies in association with detailed observation of the flare process and coronal magnetic structures. Interplanetary acceleration has now gone into a consolidation phase, with theories being worked out in detail and checked against observation.
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NASA Technical Reports Server (NTRS)
1988-01-01
The Deep Space Network (DSN) is the largest and most sensitive scientific telecommunications and radio navigation network in the world. Its principal responsibilities are to support unmanned interplanetary spacecraft missions and to support radio and radar astronomy observations in the exploration of the solar system and the universe. The DSN facilities and capabilities as of January 1988 are described.
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The Deep Impact Network Experiment Operations Center Monitor and Control System
NASA Technical Reports Server (NTRS)
Wang, Shin-Ywan (Cindy); Torgerson, J. Leigh; Schoolcraft, Joshua; Brenman, Yan
2009-01-01
The Interplanetary Overlay Network (ION) software at JPL is an implementation of Delay/Disruption Tolerant Networking (DTN) which has been proposed as an interplanetary protocol to support space communication. The JPL Deep Impact Network (DINET) is a technology development experiment intended to increase the technical readiness of the JPL implemented ION suite. The DINET Experiment Operations Center (EOC) developed by JPL's Protocol Technology Lab (PTL) was critical in accomplishing the experiment. EOC, containing all end nodes of simulated spaces and one administrative node, exercised publish and subscribe functions for payload data among all end nodes to verify the effectiveness of data exchange over ION protocol stacks. A Monitor and Control System was created and installed on the administrative node as a multi-tiered internet-based Web application to support the Deep Impact Network Experiment by allowing monitoring and analysis of the data delivery and statistics from ION. This Monitor and Control System includes the capability of receiving protocol status messages, classifying and storing status messages into a database from the ION simulation network, and providing web interfaces for viewing the live results in addition to interactive database queries.
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CFDP for Interplanetary Overlay Network
NASA Technical Reports Server (NTRS)
Burleigh, Scott C.
2011-01-01
The CCSDS (Consultative Committee for Space Data Systems) File Delivery Protocol for Interplanetary Overlay Network (CFDP-ION) is an implementation of CFDP that uses IO' s DTN (delay tolerant networking) implementation as its UT (unit-data transfer) layer. Because the DTN protocols effect automatic, reliable transmission via multiple relays, CFDP-ION need only satisfy the requirements for Class 1 ("unacknowledged") CFDP. This keeps the implementation small, but without loss of capability. This innovation minimizes processing resources by using zero-copy objects for file data transmission. It runs without modification in VxWorks, Linux, Solaris, and OS/X. As such, this innovation can be used without modification in both flight and ground systems. Integration with DTN enables the CFDP implementation itself to be very simple; therefore, very small. Use of ION infrastructure minimizes consumption of storage and processing resources while maximizing safety.
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Aizawa, Hidenori; Bianco, Isaac H; Hamaoka, Takanori; Miyashita, Toshio; Uemura, Osamu; Concha, Miguel L; Russell, Claire; Wilson, Stephen W; Okamoto, Hitoshi
2005-02-08
The habenulae are part of an evolutionarily highly conserved limbic-system conduction pathway that connects telencephalic nuclei to the interpeduncular nucleus (IPN) of the midbrain . In zebrafish, unilateral activation of the Nodal signaling pathway in the left brain specifies the laterality of the asymmetry of habenular size . We show "laterotopy" in the habenulo-interpeduncular projection in zebrafish, i.e., the stereotypic, topographic projection of left-sided habenular axons to the dorsal region of the IPN and of right-sided habenular axons to the ventral IPN. This asymmetric projection is accounted for by a prominent left-right (LR) difference in the size ratio of the medial and lateral habenular sub-nuclei, each of which specifically projects either to ventral or dorsal IPN targets. Asymmetric Nodal signaling directs the orientation of laterotopy but is dispensable for the establishment of laterotopy itself. Our results reveal a mechanism by which information distributed between left and right sides of the brain can be transmitted bilaterally without loss of LR coding, which may play a crucial role in functional lateralization of the vertebrate brain .
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Clark, Benjamin J.; Sarma, Asha; Taube, Jeffrey S.
2009-01-01
Previous research has identified a population of cells throughout the limbic system that discharge as a function of the animals head direction (HD). Altering normal motor cues can alter the HD cell responses and disrupt the updating of their preferred firing directions, thus suggesting that motor cues contribute to processing the HD signal. A pathway that conveys motor information may stem from the interpeduncular nucleus (IPN), a brain region that has reciprocal connections with HD cell circuitry. To test this hypothesis, we produced electrolytic or neurotoxic lesions of the IPN and recorded HD cells in the anterior dorsal thalamus (ADN) of rats. Direction-specific firing remained present in the ADN after lesions of the IPN, but measures of HD cell properties showed that cells had reduced peak firing rates, large directional firing ranges, and firing that predicted the animal’s future heading more than in intact controls. Furthermore, preferred firing directions were moderately less influenced by rotation of a salient visual landmark. Finally, the preferred directions of cells in lesioned rats exhibited large shifts when the animals foraged for scattered food-pellets in a darkened environment and when locomoting from a familiar environment to a novel one. We propose that the IPN contributes motor information about the animal’s movements to the HD cell circuitry. Further, these results suggest that the IPN plays a broad role in the discharge properties and stability of direction-specific activity in the HD cell circuit. PMID:19144850
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Deep Space Network Antenna Monitoring Using Adaptive Time Series Methods and Hidden Markov Models
NASA Technical Reports Server (NTRS)
Smyth, Padhraic; Mellstrom, Jeff
1993-01-01
The Deep Space Network (DSN)(designed and operated by the Jet Propulsion Laboratory for the National Aeronautics and Space Administration (NASA) provides end-to-end telecommunication capabilities between earth and various interplanetary spacecraft throughout the solar system.
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Kim, Sun-Young; Olives, Casey; Sheppard, Lianne; Sampson, Paul D; Larson, Timothy V; Keller, Joshua P; Kaufman, Joel D
2017-01-01
Recent cohort studies have used exposure prediction models to estimate the association between long-term residential concentrations of fine particulate matter (PM2.5) and health. Because these prediction models rely on PM2.5 monitoring data, predictions for times before extensive spatial monitoring present a challenge to understanding long-term exposure effects. The U.S. Environmental Protection Agency (EPA) Federal Reference Method (FRM) network for PM2.5 was established in 1999. We evaluated a novel statistical approach to produce high-quality exposure predictions from 1980 through 2010 in the continental United States for epidemiological applications. We developed spatio-temporal prediction models using geographic predictors and annual average PM2.5 data from 1999 through 2010 from the FRM and the Interagency Monitoring of Protected Visual Environments (IMPROVE) networks. Temporal trends before 1999 were estimated by using a) extrapolation based on PM2.5 data in FRM/IMPROVE, b) PM2.5 sulfate data in the Clean Air Status and Trends Network, and c) visibility data across the Weather Bureau Army Navy network. We validated the models using PM2.5 data collected before 1999 from IMPROVE, California Air Resources Board dichotomous sampler monitoring (CARB dichot), the Children's Health Study (CHS), and the Inhalable Particulate Network (IPN). In our validation using pre-1999 data, the prediction model performed well across three trend estimation approaches when validated using IMPROVE and CHS data (R2 = 0.84-0.91) with lower R2 values in early years. Model performance using CARB dichot and IPN data was worse (R2 = 0.00-0.85) most likely because of fewer monitoring sites and inconsistent sampling methods. Our prediction modeling approach will allow health effects estimation associated with long-term exposures to PM2.5 over extended time periods ≤ 30 years. Citation: Kim SY, Olives C, Sheppard L, Sampson PD, Larson TV, Keller JP, Kaufman JD. 2017. Historical prediction modeling approach for estimating long-term concentrations of PM2.5 in cohort studies before the 1999 implementation of widespread monitoring. Environ Health Perspect 125:38-46; http://dx.doi.org/10.1289/EHP131.
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Eggan, Branden L; McCallum, Sarah E
2017-01-01
The medial habenula-interpeduncular nucleus (MHb-IPN) pathway has recently been shown to modulate multiple effects nicotine in vivo, however it remains unclear which receptor subtypes in this pathway are critical for mediating these responses. To identify MHb and IPN receptors that play a role in nicotine reward, we studied receptors prevalent in these nuclei, including nicotinic acetylcholine receptors (nAChRs) and the receptor for substance P (neuokinin-1; NK1 receptor) using a model of behavioral and neurochemical sensitization to nicotine. Our results show that blockade of the α3β4 nAChR in the MHb, but not the IPN prevented increases in locomotor responding as well as increases in accumbal dopamine overflow in sensitized animals. Additionally, when NK1 receptors were blocked in the IPN, but not the MHb, a similar effect on sensitized responding was seen. Together, these results suggest that the MHb and IPN differentially modulate nicotine sensitization. Because the neurotransmission within these brain regions is primarily cholinergic and substance P ergic and these receptors are expressed in high density in both nuclei, these results could suggest a different neurophysiological signaling role or different neuroanatomical location of these receptors in this pathway. Furthermore, while α3β4 nAChRs have been suggested as a possible pharmacological target for nicotine addiction, this is the first evidence that substance P also plays a role in mediating responding to nicotine. Copyright © 2016 Elsevier B.V. All rights reserved.
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NASA Technical Reports Server (NTRS)
1975-01-01
The objectives, functions, and organization of the Deep Space Network are summarized along with deep space station, ground communication, and network operations control capabilities. Mission support of ongoing planetary/interplanetary flight projects is discussed with emphasis on Viking orbiter radio frequency compatibility tests, the Pioneer Venus orbiter mission, and Helios-1 mission status and operations. Progress is also reported in tracking and data acquisition research and technology, network engineering, hardware and software implementation, and operations.
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The Viability of a DTN System for Current Military Application
2013-03-01
Agency (DARPA) Disruption-Tolerant Networking program and the Internet Research Task Force (IRTF) DTN Research Group made significant strides toward...Disruption-Tolerant Networks A Primer,” Interplanetary Internet Special Interest Group, 2012. [4] D. T. N. R. Group, “Compiling DTN2,” Internet Research Task
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Sergeyeva, T A; Slinchenko, O A; Gorbach, L A; Matyushov, V F; Brovko, O O; Piletsky, S A; Sergeeva, L M; Elska, G V
2010-02-05
Portable biomimetic sensor devices for the express control of phenols content in water were developed. The synthetic binding sites mimicking active site of the enzyme tyrosinase were formed in the structure of free-standing molecularly imprinted polymer membranes. Molecularly imprinted polymer membranes with the catalytic activity were obtained by co-polymerization of the complex Cu(II)-catechol-urocanic acid ethyl ester with (tri)ethyleneglycoldimethacrylate, and oligourethaneacrylate. Addition of the elastic component oligourethaneacrylate provided formation of the highly cross-linked polymer with the catalytic activity in a form of thin, flexible, and mechanically stable membrane. High accessibility of the artificial catalytic sites for the interaction with the analyzed phenol molecules was achieved due to addition of linear polymer (polyethyleneglycol Mw 20,000) to the initial monomer mixture before the polymerization. As a result, typical semi-interpenetrating polymer networks (semi-IPNs) were formed. The cross-linked component of the semi-IPN was represented by the highly cross-linked catalytic molecularly imprinted polymer, while the linear one was represented by polyethyleneglycol Mw 20,000. Extraction of the linear polymer from the fully formed semi-IPN resulted in formation of large pores in the membranes' structure. Concentration of phenols in the analyzed samples was detected using universal portable device oxymeter with the oxygen electrode in a close contact with the catalytic molecularly imprinted polymer membrane as a transducer. The detection limit of phenols detection using the developed sensor system based on polymers-biomimics with the optimized composition comprised 0.063 mM, while the linear range of the sensor comprised 0.063-1 mM. The working characteristics of the portable sensor devices were investigated. Storage stability of sensor systems at room temperature comprised 12 months (87%). As compared to traditional methods of phenols detection the developed sensor system is characterized by simplicity of operation, compactness, and low cost. Copyright 2009 Elsevier B.V. All rights reserved.
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NASA Astrophysics Data System (ADS)
Rodríguez-Cantó, Pedro J.; Martínez-Marco, Mariluz; Abargues, Rafael; Latorre-Garrido, Victor; Martínez-Pastor, Juan P.
2013-03-01
In this work, we present a novel patternable conducting nanocomposite containing gold nanoparticles. Here, the in-situ polymerization of 3T is carried out using HAuCl4 as oxidizing agent inside PMMA as host matrix. During the bake step, the gold salt is also reduced from Au(III) to Au(0) generating Au nanoparticles in the interpenetrating polymer network (IPN) system. We found that this novel multifunctional resist shows electrical conductivity and plasmonic properties as well as potential patterning capability provided by the host matrix. The resulting nanocomposite has been investigated by TEM and UV-Vis spectroscopy. Electrical characterization was also conducted for different concentration of 3T and Au(III) following a characteristic percolation behaviour. Conductivities values from 10-5 to 10 S/cm were successfully obtained depending on the IPN formulation. Moreover, The Au nanoparticles generated exhibited a localized surface plasmon resonance at around 520 nm. This synthetic approach is of potential application to modify the conductivity of numerous insulating polymers and synthesize Au nanoparticles preserving to some extent their physical and chemical properties. In addition, combination of optical properties (Plasmonics), electrical, and lithographic capability in the same material allows for the design of materials with novel functionalities and provides the basis for next generation devices.
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Does a foot-drop implant improve kinetic and kinematic parameters in the foot and ankle?
Daniilidis, Kiriakos; Jakubowitz, Eike; Thomann, Anna; Ettinger, Sarah; Stukenborg-Colsman, Christina; Yao, Daiwei
2017-04-01
Unlike the drop foot therapy with ortheses, the therapeutic effect of an implantable peroneus nerve stimulator (iPNS) is not well described. IPNS is a dynamic therapy option which is placed directly to the motoric part of the peroneal nerve and evokes a dorsiflexion of the paralysed foot. This retrospective study evaluates the kinematics and kinetics in drop foot patients who were treated with an iPNS. 18 subjects (mean age 51.3 years) with a chronic stroke-related drop foot were treated with an implantable peroneal nerve stimulator. After a mean follow-up from 12.5 months, kinematics and kinetics as well as spatiotemporal parameters were evaluated and compared in activated and deactivated iPNS. Therefore, a gait analysis with motion capture system (Vicon Motion System Ltd®, Oxford, UK) and Plug-in-Gait model was performed. The study showed significantly improved results in ankle dorsiflexion from 6.8° to 1.8° at the initial contact and from -7.3° to 0.9° during swing phase (p ≤ 0.004 and p ≤ 0.005, respectively). Likewise, we could measure improved kinetics, i.a. with a statistically significant improvement in vertical ground reaction force at loading response from 99.76 to 106.71 N/kg (p = 0.043). Enhanced spatiotemporal results in cadence, douple support, stride length, and walking speed could also be achieved, but without statistical significance (p > 0.05). The results show statistically significant improvement in ankle dorsiflexion and vertical ground reaction forces. These facts indicate a more gait stability and gait efficacy. Therefore, the use of an iPNS appears an encouraging therapeutic option for patients with a stroke-related drop foot.
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Vincenz, Daniel; Wernecke, Kerstin E A; Fendt, Markus; Goldschmidt, Jürgen
2017-08-14
Fear is an important behavioral system helping humans and animals to survive potentially dangerous situations. Fear can be innate or learned. Whereas the neural circuits underlying learned fear are already well investigated, the knowledge about the circuits mediating innate fear is still limited. We here used a novel, unbiased approach to image in vivo the spatial patterns of neural activity in odor-induced innate fear behavior in rats. We intravenously injected awake unrestrained rats with a 99m-technetium labeled blood flow tracer (99mTc-HMPAO) during ongoing exposure to fox urine or water as control, and mapped the brain distribution of the trapped tracer using single-photon emission computed tomography (SPECT). Upon fox urine exposure blood flow increased in a number of brain regions previously associated with odor-induced innate fear such as the amygdala, ventromedial hypothalamus and dorsolateral periaqueductal grey, but, unexpectedly, decreased at higher significance levels in the interpeduncular nucleus (IPN). Significant flow changes were found in regions monosynaptically connected to the IPN. Flow decreased in the dorsal tegmentum and entorhinal cortex. Flow increased in the habenula (Hb) and correlated with odor effects on behavioral defensive strategy. Hb lesions reduced avoidance of but increased approach to the fox urine while IPN lesions only reduced avoidance behavior without approach behavior. Our study identifies a new component, the IPN, of the neural circuit mediating odor-induced innate fear behavior in mammals and suggests that the evolutionarily conserved Hb-IPN system, which has recently been implicated in cued fear, also forms an integral part of the innate fear circuitry. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.
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Technologies for unattended network operations
NASA Technical Reports Server (NTRS)
Jaworski, Allan; Odubiyi, Jide; Holdridge, Mark; Zuzek, John
1991-01-01
The necessary network management functions for a telecommunications, navigation and information management (TNIM) system in the framework of an extension of the ISO model for communications network management are described. Various technologies that could substantially reduce the need for TNIM network management, automate manpower intensive functions, and deal with synchronization and control at interplanetary distances are presented. Specific technologies addressed include the use of the ISO Common Management Interface Protocol, distributed artificial intelligence for network synchronization and fault management, and fault-tolerant systems engineering.
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Solar Wind drivers affecting GIC magnitude in New Zealand.
NASA Astrophysics Data System (ADS)
Mac Manus, D. H.; Rodger, C. J.; Dalzell, M.; Petersen, T.; Clilverd, M. A.
2017-12-01
Interplanetary shocks arriving at the Earth drive magnetosphere and ionosphere current systems. Ground based magnetometers detect the time derivation of the horizontal magnetic field (dBH/dt) which can indicate the strength of these ionospheric currents. The strong dBH/dt spikes have been observed to cause large Geomagnetically Induced Currents (GIC) in New Zealand. Such could, potentially lead to large scale damage to technological infrastructure such as power network transformers; one transformer was written off in New Zealand after a sudden commencement on 6 November 2001. The strength of the incoming interplanetary shocks are monitored by satellite measurements undertaken at the L1 point. Such measurements could give power network operators a 20-60 minute warning before potentially damaging GIC occurs. In this presentation we examine solar wind measurements from the Advanced Composition Explorer (ACE), Wind, and the Solar and Heliospheric Observatory (SOHO). We contrast those solar wind observations with GIC measured in New Zealand's South Island from 2001 to 2016. We are searching for a consistent relationship between the incoming interplanetary shock and the GIC magnitude. Such a relationship would allow Transpower New Zealand Limited a small time window to implement mitigation plans in order to restrict any GIC-caused damage.
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Integrated RF/Optical Interplanetary Networking Preliminary Explorations and Empirical Results
NASA Technical Reports Server (NTRS)
Raible, Daniel E.; Hylton, Alan G.
2012-01-01
Over the last decade interplanetary telecommunication capabilities have been significantly expanded--specifically in support of the Mars exploration rover and lander missions. NASA is continuing to drive advances in new, high payoff optical communications technologies to enhance the network to Gbps performance from Mars, and the transition from technology demonstration to operational system is examined through a hybrid RF/optical approach. Such a system combines the best features of RF and optical communications considering availability and performance to realize a dual band trunk line operating within characteristic constraints. Disconnection due to planetary obscuration and solar conjunction, link delays, timing, ground terminal mission congestion and scheduling policy along with space and atmospheric weather disruptions all imply the need for network protocol solutions to ultimately manage the physical layer in a transparent manner to the end user. Delay Tolerant Networking (DTN) is an approach under evaluation which addresses these challenges. A multi-hop multi-path hybrid RF and optical test bed has been constructed to emulate the integrated deep space network and to support protocol and hardware refinement. Initial experimental results characterize several of these challenges and evaluate the effectiveness of DTN as a solution to mitigate them.
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NASA Technical Reports Server (NTRS)
Alania, M. V.; Aslamazashvili, R. G.; Bochorishvili, T.; Djapiashvili, T. V.; Tkemaladze, V. S.
1985-01-01
Results of the numerical solution of the anistoropic diffusion equation are presented. The modulation depth of galactic cosmic rays is defined by the degree of curvature of the neutral current sheet in the heliosphere. The effect of the regular interplanetary magnetic field (IMF) on cosmic ray anisotropy in the period of solar activity minimum (in 1976) is analyzed by the data of the neutron super-monitors of the world network, and the heliolatitudinal gradient and cosmic ray diffusion coefficient are defined.
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JSTO Science and Technology Update. Volume 1, Number 2, Winter 2011
2011-01-01
Figure 2. Passage of methyl salicylate simulant through an expanded Teflon control (blue), the open IPN (black) and the closed IPN (pink). The...membrane (blue). ET is used in breathable sports clothing. The materials were challenged using vapor from the CW agent simulant methyl salicylate (MS). The...was challenged with vapor from chloroethyl ethyl sulfide (a mus- tard gas simulant), benzene, and liquid with dissolved methyl parathion (a V-agent
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Kim, Sun-Young; Olives, Casey; Sheppard, Lianne; Sampson, Paul D.; Larson, Timothy V.; Keller, Joshua P.; Kaufman, Joel D.
2016-01-01
Introduction: Recent cohort studies have used exposure prediction models to estimate the association between long-term residential concentrations of fine particulate matter (PM2.5) and health. Because these prediction models rely on PM2.5 monitoring data, predictions for times before extensive spatial monitoring present a challenge to understanding long-term exposure effects. The U.S. Environmental Protection Agency (EPA) Federal Reference Method (FRM) network for PM2.5 was established in 1999. Objectives: We evaluated a novel statistical approach to produce high-quality exposure predictions from 1980 through 2010 in the continental United States for epidemiological applications. Methods: We developed spatio-temporal prediction models using geographic predictors and annual average PM2.5 data from 1999 through 2010 from the FRM and the Interagency Monitoring of Protected Visual Environments (IMPROVE) networks. Temporal trends before 1999 were estimated by using a) extrapolation based on PM2.5 data in FRM/IMPROVE, b) PM2.5 sulfate data in the Clean Air Status and Trends Network, and c) visibility data across the Weather Bureau Army Navy network. We validated the models using PM2.5 data collected before 1999 from IMPROVE, California Air Resources Board dichotomous sampler monitoring (CARB dichot), the Children’s Health Study (CHS), and the Inhalable Particulate Network (IPN). Results: In our validation using pre-1999 data, the prediction model performed well across three trend estimation approaches when validated using IMPROVE and CHS data (R2 = 0.84–0.91) with lower R2 values in early years. Model performance using CARB dichot and IPN data was worse (R2 = 0.00–0.85) most likely because of fewer monitoring sites and inconsistent sampling methods. Conclusions: Our prediction modeling approach will allow health effects estimation associated with long-term exposures to PM2.5 over extended time periods ≤ 30 years. Citation: Kim SY, Olives C, Sheppard L, Sampson PD, Larson TV, Keller JP, Kaufman JD. 2017. Historical prediction modeling approach for estimating long-term concentrations of PM2.5 in cohort studies before the 1999 implementation of widespread monitoring. Environ Health Perspect 125:38–46; http://dx.doi.org/10.1289/EHP131 PMID:27340825
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Developments in high-precision gamma-ray burst source studies
NASA Technical Reports Server (NTRS)
Cline, T. L.
1982-01-01
The source location data analyzed by the first and second interplanetary gamma ray burst spacecraft networks are reviewed. The possibilities of additional networks and of related studies in other disciplines, and the prospects for real time optical transient observations and for the definition of gamma ray burst sources by optical transient astronomy are also reviewed.
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Blackburn, J M; Sutherland, J D; Baldwin, J E
1995-06-06
Isopenicillin N synthase (IPNS) catalyzes the oxidative cyclization of delta-(L-alpha-aminoadipoyl)-L-cysteinyl-D-valine to isopenicillin N. It is proposed that the multiple products produced from certain substrate analogues result from pathway branching after formation of a ferryl oxene intermediate. We have been interested in ascertaining the reasons for multiple product formation. One possibility is that the products are predisposed toward formation once the beta-lactam ring and the ferryl oxene are produced. Alternately, the products may be persuaded into being by the enzyme restricting conformations such that otherwise less favorable chemistry can take place. With the existing description of the IPNS catalytic cycle, this fundamental question has not been answerable. We describe here the application of a heuristic method to resolve this key issue. It was reasoned that by comparing the ratios of products formed by a set of perturbed IPNS variants it might be possible to generate qualitative information about the relative magnitude of certain activation parameters. If certain product ratios are affected but others are not, then it should be possible to say which steps in the reaction are dictated merely by chemical fundamentals and which steps are directly effected by the enzyme. In this paper we report the high-level expression, purification, and characterization of four IPNS isozymes. Comparison of the product ratios obtained on incubation of unnatural substrate analogues with four IPNS isozymes corresponding to perturbed active site variants shows substantial variation in some cases and little in others. Interpretation of the results obtained with delta-(L-alpha-aminoadipoyl)-L-cysteinyl-D-alpha-aminobutyrate (ACAB) allows conclusions to be drawn regarding the role of the enzyme in restricting available conformations of the natural substrate to disfavor certain otherwise chemically favorable pathways and hence products. The results obtained with delta-(L-alpha-aminoadipoyl)-L-cysteinyl-D-allylglycine, while rather more complex, substantiate the conclusions drawn from the ACAB data. A major conclusion is that, in the oxidation of ACV, IPNS is a negative catalyst of cepham formation but a positive catalyst of penam formation.
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Barrett, A; Depledge, M H; Powles, R L
1983-07-01
Idiopathic and infective interstitial pneumonitis (IPn) is a common complication after bone marrow transplantation (BMT) in many centers and carries a high mortality. We report here a series of 107 patients with acute leukemia grafted at the Royal Marsden Hospital in which only 11 (10.3%) developed IPn and only 5 died (5%). Only one case of idiopathic IPn was seen. Factors which may account for this low incidence are discussed. Sixty of 107 patients were transplanted in first remission of acute myeloid leukemia (AML) and were therefore in good general condition. Lung radiation doses were carefully monitored and doses of 10.5 Gy were not exceeded except in a group of 16 patients in whom a study of escalating doses of TBI (up to 13 Gy) was undertaken. The dose rate used for total body irradiation (TBI) was lower than that used in other centers and as demonstrated elsewhere by ourselves and others, reduction of dose rate to less than 0.05 Gy/min may be expected to lead to substantial reduction in lung damage. Threshold doses of approximately 8 Gy for IPn have been reported, but within the dose range of 8 to 10.5 Gy we suggest that dose rate may significantly affect the incidence. Data so far available suggest a true improvement in therapeutic ratio for low dose rate single fraction TBI compared with high dose rate.
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A RP-HPLC method for quantification of diclofenac sodium released from biological macromolecules.
Bhattacharya, Shiv Sankar; Banerjee, Subham; Ghosh, Ashoke Kumar; Chattopadhyay, Pronobesh; Verma, Anurag; Ghosh, Amitava
2013-07-01
Interpenetrating network (IPN) microbeads of sodium carboxymethyl locust bean gum (SCMLBG) and sodium carboxymethyl cellulose (SCMC) containing diclofenac sodium (DS), a nonsteroidal anti-inflammatory drug, were prepared by single water-in-water (w/w) emulsion gelation process using AlCl3 as cross-linking agent in a complete aqueous environment. Pharmacokinetic study of these IPN microbeads was then carried out by a simple and feasible high-performance liquid chromatographic method with UV detection which was developed and validated for the quantification of diclofenac sodium in rabbit plasma. The chromatographic separation was carried out in a Hypersil BDS, C18 column (250 mm × 4.6 mm; 5 m). The mobile phase was a mixture of acetonitrile and methanol (70:30, v/v) at a flow rate of 1.0 ml/min. The UV detection was set at 276 nm. The extraction recovery of diclofenac sodium in plasma of three quality control (QC) samples was ranged from 81.52% to 95.29%. The calibration curve was linear in the concentration range of 20-1000 ng/ml with the correlation coefficient (r(2)) above 0.9951. The method was specific and sensitive with the limit of quantification of 20 ng/ml. In stability tests, diclofenac sodium in rabbit plasma was stable during storage and assay procedure. Copyright © 2013. Published by Elsevier B.V.
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The telecommunications and data acquisition
NASA Technical Reports Server (NTRS)
Renzetti, N. A. (Editor)
1980-01-01
Radio astronomy and radio interferometry at microwave frequencies are discussed. Other topics concerning the Deep Space Network include program planning, planetary and interplanetary mission support, tracking and ground based navigation, communications, and station control and system technology.
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McNeill, Luke A.; Brown, Toby J. N.; Sami, Malkit; Clifton, Ian J.; Burzlaff, Nicolai I.; Claridge, Timothy D. W.; Adlington, Robert M.; Baldwin, Jack E.
2017-01-01
Abstract Isopenicillin N synthase (IPNS) catalyses the four‐electron oxidation of a tripeptide, l‐δ‐(α‐aminoadipoyl)‐l‐cysteinyl‐d‐valine (ACV), to give isopenicillin N (IPN), the first‐formed β‐lactam in penicillin and cephalosporin biosynthesis. IPNS catalysis is dependent upon an iron(II) cofactor and oxygen as a co‐substrate. In the absence of substrate, the carbonyl oxygen of the side‐chain amide of the penultimate residue, Gln330, co‐ordinates to the active‐site metal iron. Substrate binding ablates the interaction between Gln330 and the metal, triggering rearrangement of seven C‐terminal residues, which move to take up a conformation that extends the final α‐helix and encloses ACV in the active site. Mutagenesis studies are reported, which probe the role of the C‐terminal and other aspects of the substrate binding pocket in IPNS. The hydrophobic nature of amino acid side‐chains around the ACV binding pocket is important in catalysis. Deletion of seven C‐terminal residues exposes the active site and leads to formation of a new type of thiol oxidation product. The isolated product is shown by LC‐MS and NMR analyses to be the ene‐thiol tautomer of a dithioester, made up from two molecules of ACV linked between the thiol sulfur of one tripeptide and the oxidised cysteinyl β‐carbon of the other. A mechanism for its formation is proposed, supported by an X‐ray crystal structure, which shows the substrate ACV bound at the active site, its cysteinyl β‐carbon exposed to attack by a second molecule of substrate, adjacent. Formation of this product constitutes a new mode of reaction for IPNS and non‐heme iron oxidases in general. PMID:28703303
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McNeill, Luke A; Brown, Toby J N; Sami, Malkit; Clifton, Ian J; Burzlaff, Nicolai I; Claridge, Timothy D W; Adlington, Robert M; Baldwin, Jack E; Rutledge, Peter J; Schofield, Christopher J
2017-09-18
Isopenicillin N synthase (IPNS) catalyses the four-electron oxidation of a tripeptide, l-δ-(α-aminoadipoyl)-l-cysteinyl-d-valine (ACV), to give isopenicillin N (IPN), the first-formed β-lactam in penicillin and cephalosporin biosynthesis. IPNS catalysis is dependent upon an iron(II) cofactor and oxygen as a co-substrate. In the absence of substrate, the carbonyl oxygen of the side-chain amide of the penultimate residue, Gln330, co-ordinates to the active-site metal iron. Substrate binding ablates the interaction between Gln330 and the metal, triggering rearrangement of seven C-terminal residues, which move to take up a conformation that extends the final α-helix and encloses ACV in the active site. Mutagenesis studies are reported, which probe the role of the C-terminal and other aspects of the substrate binding pocket in IPNS. The hydrophobic nature of amino acid side-chains around the ACV binding pocket is important in catalysis. Deletion of seven C-terminal residues exposes the active site and leads to formation of a new type of thiol oxidation product. The isolated product is shown by LC-MS and NMR analyses to be the ene-thiol tautomer of a dithioester, made up from two molecules of ACV linked between the thiol sulfur of one tripeptide and the oxidised cysteinyl β-carbon of the other. A mechanism for its formation is proposed, supported by an X-ray crystal structure, which shows the substrate ACV bound at the active site, its cysteinyl β-carbon exposed to attack by a second molecule of substrate, adjacent. Formation of this product constitutes a new mode of reaction for IPNS and non-heme iron oxidases in general. © 2017 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA.
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The deep space network, volume 10
NASA Technical Reports Server (NTRS)
1972-01-01
Progress on the Deep Space Network (DSN) supporting research and technology is reported. The objectives, functions and facilities of the DSN are described along with the mission support for the following: interplanetary flight projects, planetary flight projects, and manned space flight projects. Work in advanced engineering and communications systems is reported along with changes in hardware and software configurations in the DSN/MSFN tracking stations.
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Endpoint Naming for Space Delay/Disruption Tolerant Networking
NASA Technical Reports Server (NTRS)
Clare, Loren; Burleigh, Scott; Scott, Keith
2010-01-01
Delay/Disruption Tolerant Networking (DTN) provides solutions to space communication challenges such as disconnections when orbiters lose line-of-sight with landers, long propagation delays over interplanetary links, and other operational constraints. DTN is critical to enabling the future space internetworking envisioned by NASA. Interoperability with international partners is essential and standardization is progressing through both the CCSDS and the IETF.
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The Mars Telecommunications Orbiter a key asset in the Mars Network
NASA Technical Reports Server (NTRS)
Abilleira, Fernando
2006-01-01
The Mars Telecommunications Orbiter (MTO) to be launched in 2009 will play a key role in the Mars Network since it will be the first interplanetary mission whose primary objective is to provide communications to existing and upcoming Mars missions, This paper presents a basic description of the primary mission an provides trajectory information for the Mars Telecommunication Orbiter.
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The deep space network, volume 6
NASA Technical Reports Server (NTRS)
1971-01-01
Progress on Deep Space Network (DSN) supporting research and technology is presented, together with advanced development and engineering, implementation, and DSN operations of flight projects. The DSN is described. Interplanetary and planetary flight projects and radio science experiments are discussed. Tracking and navigational accuracy analysis, communications systems and elements research, and supporting research are considered. Development of the ground communications and deep space instrumentation facilities is also presented. Network allocation schedules and angle tracking and test development are included.
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DOE Office of Scientific and Technical Information (OSTI.GOV)
Feng Jiang; Peisach, J.; Lijune Ming
Electron spin echo envelope modulation spectroscopy (ESEEM) was used to study the active site structure of isopenicillin N synthase (IPNS) from Cephalosporium acremonium with Cu(II) as a spectroscopic probe. Fourier transform of the simulated electron spin-echo envelope for the Cu(II)-substituted enzyme, Cu(II)IPNS, revealed two nearly magnetically equivalent, equatorially coordinated His imidazoles. The superhyperfine coupling constant, A{sub iso}, for the remote {sup 14}N of each imidazole was 1.65 MHz. The binding of substrate to the enzyme altered the magnetic coupling so that A{sub iso} is 1.30 MHz for one nitrogen and 2.16 MHz for the other. From a comparison of themore » ESSEM of Cu(II)IPNS in D{sub 2}O and H{sub 2}O, it is suggested that water is a ligand of Cu(II) and this is displaced upon the addition of substrate.« less
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Šafka Brožková, D; Haberlová, J; Mazanec, R; Laštůvková, J; Seeman, P
2016-08-01
Hereditary motor and sensory neuropathy type Russe (HMSNR), also called CMT4G, is an autosomal recessive inherited peripheral neuropathy (IPN) caused by a founder mutation in the HK1 gene. HMSNR affects only patients with Roma origin, similar to the better known HMSN type Lom clarified earlier. By testing IPN patients with Roma origin, we realized that HMSNR affects surprisingly many patients in the Czech Republic. HMSNR is one of the most frequent types of IPN in this country and appears to be twice more frequent than HMSNL. Pronounced lower limb atrophies and severe deformities often lead to walking inability in even young patients, but hands are usually only mildly affected even after many years of disease duration. The group of 20 patients with HMSNR presented here is the first report about the prevalence of HMSNR from central Europe. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
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Autophagy as an Emerging Common Pathomechanism in Inherited Peripheral Neuropathies
Haidar, Mansour; Timmerman, Vincent
2017-01-01
The inherited peripheral neuropathies (IPNs) comprise a growing list of genetically heterogeneous diseases. With mutations in more than 80 genes being reported to cause IPNs, a wide spectrum of functional consequences is expected to follow this genotypic diversity. Hence, the search for a common pathomechanism among the different phenotypes has become the holy grail of functional research into IPNs. During the last decade, studies on several affected genes have shown a direct and/or indirect correlation with autophagy. Autophagy, a cellular homeostatic process, is required for the removal of cell aggregates, long-lived proteins and dead organelles from the cell in double-membraned vesicles destined for the lysosomes. As an evolutionarily highly conserved process, autophagy is essential for the survival and proper functioning of the cell. Recently, neuronal cells have been shown to be particularly vulnerable to disruption of the autophagic pathway. Furthermore, autophagy has been shown to be affected in various common neurodegenerative diseases of both the central and the peripheral nervous system including Alzheimer’s, Parkinson’s, and Huntington’s diseases. In this review we provide an overview of the genes involved in hereditary neuropathies which are linked to autophagy and we propose the disruption of the autophagic flux as an emerging common pathomechanism. We also shed light on the different steps of the autophagy pathway linked to these genes. Finally, we review the concept of autophagy being a therapeutic target in IPNs, and the possibilities and challenges of this pathway-specific targeting. PMID:28553203
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Surviving to tell the tale : Argonne's Intense Pulsed Neutron Source from an ecosystem perspective.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Westfall, C.; Office of The Director
2010-07-01
At first glance the story of the Intense Pulsed Neutron Source (IPNS), an accelerator-driven neutron source for exploring the structure of materials through neutron scattering, seems to be one of puzzling ups and downs. For example, Argonne management, Department of Energy officials, and materials science reviewers continued to offer, then withdraw, votes of confidence even though the middling-sized IPNS produced high-profile research, including work that made the cover of Nature in 1987. In the midst of this period of shifting opinion and impressive research results, some Argonne materials scientists were unenthusiastic, members of the laboratory's energy physics group were keymore » supporters, and materials scientists at another laboratory provided, almost fortuitously, a new lease on life. What forces shaped the puzzling life cycle of the IPNS? And what role - if any - did the moderate price tag and the development of scientific and technological ideas play in the course it took? To answer these questions this paper looks to an ecosystem metaphor for inspiration, exploring how opinions, ideas, and machinery emerged from the interrelated resource economies of Argonne, the DOE, and the materials science community by way of a tangled web of shifting group interactions. The paper will conclude with reflections about what the resulting focus on relationality explains about the IPNS story as well as the underlying dynamic that animates knowledge production at U.S. national laboratories.« less
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Using The Global Positioning System For Earth Orbiter and Deep Space Network
NASA Technical Reports Server (NTRS)
Lichten, Stephen M.; Haines, Bruce J.; Young, Lawrence E.; Dunn, Charles; Srinivasan, Jeff; Sweeney, Dennis; Nandi, Sumita; Spitzmesser, Don
1994-01-01
The Global Positioning System (GPS) can play a major role in supporting orbit and trajectory determination for spacecraft in a wide range of applications, including low-Earth, high-earth, and even deep space (interplanetary) tracking.
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Influence of hydrophobic modification in alginate-based hydrogels for biomedical applications
NASA Astrophysics Data System (ADS)
Choudhary, Soumitra
Alginate has been exploited commercially for decades in foods, textiles, paper, pharmaceutical industries, and also as a detoxifier for removing heavy metals. Alginate is also popular in cell encapsulation because of its relatively mild gelation protocol and simple chemistry with which biological active entities can be immobilized. Surface modification of alginate gels has been explored to induce desired cell interactions with the gel matrix. These modifications alter the bulk properties, which strongly determine on how cells feel and response to the three-dimensional microenvironment. However, there is a need to develop strategies to engineer functionalities into bulk alginate hydrogels that not only preserve their inherent qualities but are also less toxic. In this thesis, our main focus was to optimize the mechanical properties of alginate-based hydrogels, and by doing so control the performance of the biomaterials. In the first scheme, we used alginate and hydrophobically modified ethyl hydroxy ethyl cellulose as components in interpenetrating polymer network (IPN) gels. The second network was used to control gelation time and rheological properties. We believe these experiments also may provide insight into the mechanical and structural properties of more complex biopolymer gels and naturally-occurring IPNs. Next, we worked on incorporating a hydrophobic moiety directly into the alginate chain, resulting in materials for extended release of hydrophobic drugs. We successfully synthesized hydrophobically modified alginate (HMA) by attaching octylamine groups onto the alginate backbone by standard carbodiimide based amide coupling reaction. Solubility of several model hydrophobic drugs in dilute HMA solutions was found to be increased by more than an order of magnitude. HMA hydrogels, prepared by crosslinking the alginate chains with calcium ions, were found to exhibit excellent mechanical properties (modulus ˜100 kPa) with release extended upto 5 days. Ability to vary the hydrophobic tails, degree of substitution, and crosslinker density gave us handles to tune the properties of the materials. Finally we will show how modulus of the alginate gels can be used to influence the proliferation and differentiation of encapsulated neural stem cells. A preliminary attempt was also made to develop three dimensional "life-like" vasculature network made from alginate tubes and other biomaterials.
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NASA Astrophysics Data System (ADS)
Bleuel, M.; Bröll, M.; Lang, E.; Littrell, K.; Gähler, R.; Lal, J.
2006-01-01
In this paper we report the results of our first tests of a novel proof-of-principle instrument developed at the IPNS, Argonne. The experiment was performed on the time of flight POSY1 instrument, the polarized reflectometer at the IPNS, which was modified to accommodate the apparatus. Two sets of RF-flippers were tested together, generating a modulated intensity by zero effort (MIEZE)-type neutron resonant spin echo signal which was observed at the detector using a wide neutron wavelength band.
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NASA Astrophysics Data System (ADS)
Cheung, K.-M.; Abraham, D.; Arroyo, B.; Basilio, E.; Babuscia, A.; Duncan, C.; Lee, D.; Oudrhiri, K.; Pham, T.; Staehle, R.; Waldherr, S.; Welz, G.; Wyatt, J.; Lanucara, M.; Malphrus, B.; Bellardo, J.; Puig-Suari, J.; Corpino, S.
2015-08-01
As small spacecraft venture out of Earth orbit, they will encounter challenges not experienced or addressed by the numerous low Earth orbit (LEO) CubeSat and smallsat missions staged to date. The LEO CubeSats typically use low-cost, proven CubeSat radios, antennas, and university ground stations with small apertures. As more ambitious yet cost-constrained space mission concepts to the Moon and beyond are being developed, CubeSats and smallsats have the potential to provide a more affordable platform for exploring deep space and performing the associated science. Some of the challenges that have, so far, slowed the proliferation of small interplanetary spacecraft are those of communications and navigation. Unlike Earth-orbiting spacecraft that navigate via government services such as North American Aerospace Defense Command's (NORAD's) tracking elements or the Global Positioning Satellite (GPS) system, interplanetary spacecraft would have to operate in a fundamentally different manner that allows the deep-space communications link to provide both command/telemetry and the radiometric data needed for navigation. Another challenge occurs when smallsat and CubeSat missions would involve multiple spacecraft that require near-simultaneous communication and/or navigation, but have a very limited number of ground antenna assets, as well as available spectrum, to support their links. To address these challenges, the Jet Propulsion Laboratory (JPL) and the Deep Space Network (DSN) it operates for NASA are pursuing the following efforts: (1) Developing a CubeSat-compatible, DSN-compatible transponder -- Iris -- which a commercial vendor can then make available as a product line. (2) Developing CubeSat-compatible high-gain antennas -- deployable reflectors, reflectarrays, and inflatable antennas. (3) Streamlining access and utilization processes for DSN and related services such as the Advanced Multi-Mission Operations System (AMMOS). (4) Developing methodologies for tracking and operating multiple spacecraft simultaneously, including spectrum coordination. (5) Coordination and collaboration with non-DSN facilities. This article further describes the communications and tracking challenges facing interplanetary smallsats and CubeSats, and the next-generation ground network architecture being evolved to mitigate those challenges.
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NASA Astrophysics Data System (ADS)
Bhaskar, A. T.; Vichare, G.
2017-12-01
Here, an attempt is made to develop a prediction model for SYMH and ASYH geomagnetic indices using Artificial Neural Network (ANN). SYMH and ASYH indices represent longitudinal symmetric and asymmetric component of the ring current. The ring current state depends on its past conditions therefore, it is necessary to consider its history for prediction. To account this effect Nonlinear Autoregressive Network with eXogenous inputs (NARX) is implemented. This network considers input history of 30 minutes and output feedback of 120 minutes. Solar wind parameters mainly velocity, density and interplanetary magnetic field are used as inputs. SYMH and ASYH indices during geomagnetic storms of 1998-2013, having minimum SYMH <-85 nT are used as the target for training two independent networks. We present the prediction of SYMH and ASYH indices during 9 geomagnetic storms of solar cycle 24 including the recent largest storm occurred on St. Patrick's day, 2015. The present prediction model reproduces the entire time profile of SYMH and ASYH indices along with small variations of 10-30 minutes to good extent within noise level, indicating significant contribution of interplanetary sources and past state of the magnetosphere. However, during the main phase of major storms, residuals (observed-modeled) are found to be large, suggesting influence of internal factors such as magnetospheric processes.
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The Deep Impact Network Experiment Operations Center
NASA Technical Reports Server (NTRS)
Torgerson, J. Leigh; Clare, Loren; Wang, Shin-Ywan
2009-01-01
Delay/Disruption Tolerant Networking (DTN) promises solutions in solving space communications challenges arising from disconnections as orbiters lose line-of-sight with landers, long propagation delays over interplanetary links, and other phenomena. DTN has been identified as the basis for the future NASA space communications network backbone, and international standardization is progressing through both the Consultative Committee for Space Data Systems (CCSDS) and the Internet Engineering Task Force (IETF). JPL has developed an implementation of the DTN architecture, called the Interplanetary Overlay Network (ION). ION is specifically implemented for space use, including design for use in a real-time operating system environment and high processing efficiency. In order to raise the Technology Readiness Level of ION, the first deep space flight demonstration of DTN is underway, using the Deep Impact (DI) spacecraft. Called the Deep Impact Network (DINET), operations are planned for Fall 2008. An essential component of the DINET project is the Experiment Operations Center (EOC), which will generate and receive the test communications traffic as well as "out-of-DTN band" command and control of the DTN experiment, store DTN flight test information in a database, provide display systems for monitoring DTN operations status and statistics (e.g., bundle throughput), and support query and analyses of the data collected. This paper describes the DINET EOC and its value in the DTN flight experiment and potential for further DTN testing.
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Dynamic Routing for Delay-Tolerant Networking in Space Flight Operations
NASA Technical Reports Server (NTRS)
Burleigh, Scott
2008-01-01
Computational self-sufficiency - the making of communication decisions on the basis of locally available information that is already in place, rather than on the basis of information residing at other entities - is a fundamental principle of Delay-Tolerant Networking. Contact Graph Routing is an attempt to apply this principle to the problem of dynamic routing in an interplanetary DTN. Testing continues, but preliminary results are promising.
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NASA Technical Reports Server (NTRS)
1983-01-01
Voyager, Infrared Astronomical Satellite, Galileo, Viking, Solar Mesosphere Explorer, Wide-field/Planetary Camera, Venus Mapper, International Solar Polar Mission - Solar Interplanetary Satellite, Extreme Ultraviolet Explores, Starprobe, International Halley Watch, Marine Mark II, Samex, Shuttle Imaging Radar-A, Deep Space Network, Biomedical Technology, Ocean Studies and Robotics are summarized.
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Tong, Zhihui; Ke, Lu; Li, Baiqiang; Li, Gang; Zhou, Jing; Shen, Xiao; Li, Weiqin; Li, Ning; Li, Jieshou
2016-11-10
In recent years, a step-up approach based on minimally invasive techniques was recommended by latest guidelines as initial invasive treatment for infected pancreatic necrosis (IPN). In this study, we aimed to describe a novel step-up approach for treating IPN consisting of four steps including negative pressure irrigation (NPI) and endoscopic necrosectomy (ED) as a bridge between percutaneous catheter drainage (PCD) and open necrosectomy METHODS: A retrospective review of a prospectively collected internal database of patients with a diagnosis of IPN between Jan, 2012 to Dec, 2012 at a single institution was performed. All patients underwent the same drainage strategy including four steps: PCD, NPI, ED and open necrosectomy. The demographic characteristics and clinical outcomes of study patients were analyzed. A total of 71 consecutive patients (48 males and 23 females) were included in the analysis. No significant procedure-related complication was observed and the overall mortality was +21.1 % (15 of 71 patients). Seven different strategies like PCD+ NPI, PCD+NPI+ED, PCD+open necrosectomy, etcetera, were applied in study patients and a half of them received PCD alone. In general, each patient underwent a median of 2 drainage procedures and the median total drainage duration was 11 days (interquartile range, 6-21days). This four-step approach is effective in treating IPN and adds no extra risk to patients when compared with other latest step-up strategies. The two novel techniques (NPI and ED) could offer distinct clinical benefits without posing unanticipated risks inherent to the procedures.
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Gastrointestinal Fistulas in Acute Pancreatitis With Infected Pancreatic or Peripancreatic Necrosis
Jiang, Wei; Tong, Zhihui; Yang, Dongliang; Ke, Lu; Shen, Xiao; Zhou, Jing; Li, Gang; Li, Weiqin; Li, Jieshou
2016-01-01
Abstract Gastrointestinal (GI) fistula is a well-recognized complication of acute pancreatitis (AP). However, it has been reported in limited literature. This study aimed to evaluate the incidence and outcome of GI fistulas in AP patients complicated with infected pancreatic or peripancreatic necrosis (IPN). Between 2010 and 2013 AP patients with IPN who diagnosed with GI fistula in our center were analyzed in this retrospective study. And we also conducted a comparison between patients with and without GI fistula regarding the baseline characteristics and outcomes. Over 4 years, a total of 928 AP patients were admitted into our center, of whom 119 patients with IPN were diagnosed with GI fistula and they developed 160 GI fistulas in total. Colonic fistula found in 72 patients was the most common form of GI fistula followed with duodenal fistula. All duodenal fistulas were managed by nonsurgical management. Ileostomy or colostomy was performed for 44 (61.1%) of 72 colonic fistulas. Twenty-one (29.2%) colonic fistulas were successfully treated by percutaneous drainage or continuous negative pressure irrigation. Mortality of patients with GI fistula did not differ significantly from those without GI fistula (28.6% vs 21.9%, P = 0.22). However, a significantly higher mortality (34.7%) was observed in those with colonic fistula. GI fistula is a common finding in patients of AP with IPN. Most of these fistulas can be successfully managed with different procedures depending on their sites of origin. Colonic fistula is related with higher mortality than those without GI fistula. PMID:27057908
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Kim, Young Ae; Kim, Eun Su; Hwang, Ho Kyeong; Lee, Kyung Bok; Lee, Sol; Jung, Ji Woong; Kwon, Yu Jin; Cho, Dong Hui; Park, Sang Su; Yoon, Jin; Jang, Yong-Seog
2014-01-01
Purpose: Peripheral neuropathy (PN) is known as a major contributor of the worsening of ischemic symptoms and the foot ulceration in patients with peripheral arterial occlusive disease (PAOD). However, there are few studies reporting the prevalence and risk factors for PN in PAOD. This study aimed to evaluate these issues for PN and to establish the importance of screening as additional treatment target for PN in PAOD. Materials and Methods: A total of 52 limbs with PAOD were enrolled from January 2011 to December 2012. PN was divided into radiculopathy, ischemic PN (IPN), and diabetic PN (DPN), based on electromyographic findings. We investigated the prevalence of overall PN and subtypes of PN and then analyzed the risk factors. Results: The prevalence of overall PN in PAOD was 43 of 52 limbs (82.7%). In terms of subtypes of PN, the prevalence rate of radiculopathy and IPN was 30.8% and 23.1%, respectively. DPN showed in 22 limbs (73.3%) among 30 diabetic limbs. There was no significant correlation between each type of PN and ischemic symptoms. Our analysis showed that coronary artery disease (CAD) was a significant risk factor (P=0.01) for IPN, however, did not identify any significant risk factors for DPN. Conclusion: This present study indicated that most patients with PAOD had PN and CAD was a risk factor for IPN. In particular, PAOD with diabetes represented a higher prevalence for DPN. Our study suggests that PN should be evaluated and considered as another treatment target in patients with PAOD. PMID:26217631
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Improvement of Aspergillus nidulans penicillin production by targeting AcvA to peroxisomes.
Herr, Andreas; Fischer, Reinhard
2014-09-01
Aspergillus nidulans is able to synthesize penicillin and serves as a model to study the regulation of its biosynthesis. Only three enzymes are required to form the beta lactam ring tripeptide, which is comprised of l-cysteine, l-valine and l-aminoadipic acid. Whereas two enzymes, AcvA and IpnA localize to the cytoplasm, AatA resides in peroxisomes. Here, we tested a novel strategy to improve penicillin production, namely the change of the residence of the enzymes involved in the biosynthesis. We tested if targeting of AcvA or IpnA (or both) to peroxisomes would increase the penicillin yield. Indeed, AcvA peroxisomal targeting led to a 3.2-fold increase. In contrast, targeting IpnA to peroxisomes caused a complete loss of penicillin production. Overexpression of acvA, ipnA or aatA resulted in 1.4, 2.8 and 3.1-fold more penicillin, respectively in comparison to wildtype. Simultaneous overexpression of all three enzymes resulted even in 6-fold more penicillin. Combination of acvA peroxisomal targeting and overexpression of the gene led to 5-fold increase of the penicillin titer. At last, the number of peroxisomes was increased through overexpression of pexK. A strain with the double number of peroxisomes produced 2.3 times more penicillin. These results show that penicillin production can be triggered at several levels of regulation, one of which is the subcellular localization of the enzymes. Copyright © 2014 International Metabolic Engineering Society. Published by Elsevier Inc. All rights reserved.
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Analysis of an Interplanetary Coronal Mass Ejection by a Spacecraft Radio Signal: A Case Study
NASA Astrophysics Data System (ADS)
Molera Calvés, G.; Kallio, E.; Cimo, G.; Quick, J.; Duev, D. A.; Bocanegra Bahamón, T.; Nickola, M.; Kharinov, M. A.; Mikhailov, A. G.
2017-11-01
Tracking radio communication signals from planetary spacecraft with ground-based telescopes offers the possibility to study the electron density and the interplanetary scintillation of the solar wind. Observations of the telemetry link of planetary spacecraft have been conducted regularly with ground antennae from the European Very Long Baseline Interferometry Network, aiming to study the propagation of radio signals in the solar wind at different solar elongations and distances from the Sun. We have analyzed the Mars Express spacecraft radio signal phase fluctuations while, based on a 3-D heliosphere plasma simulation, an interplanetary coronal mass ejection (ICME) crossed the radio path during one of our observations on 6 April 2015. Our measurements showed that the phase scintillation indices increased by a factor of 4 during the passage of the ICME. The method presented here confirms that the phase scintillation technique based on spacecraft signals provides information of the properties and propagation of the ICMEs in the heliosphere.
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NASA Astrophysics Data System (ADS)
Valach, F.; Revallo, M.; Hejda, P.; Bochníček, J.
2010-12-01
Our modern society with its advanced technology is becoming increasingly vulnerable to the Earth's system disorders originating in explosive processes on the Sun. Coronal mass ejections (CMEs) blasted into interplanetary space as gigantic clouds of ionized gas can hit Earth within a few hours or days and cause, among other effects, geomagnetic storms - perhaps the best known manifestation of solar wind interaction with Earth's magnetosphere. Solar energetic particles (SEP), accelerated to near relativistic energy during large solar storms, arrive at the Earth's orbit even in few minutes and pose serious risk to astronauts traveling through the interplanetary space. These and many other threats are the reason why experts pay increasing attention to space weather and its predictability. For research on space weather, it is typically necessary to examine a large number of parameters which are interrelated in a complex non-linear way. One way to cope with such a task is to use an artificial neural network for space weather modeling, a tool originally developed for artificial intelligence. In our contribution, we focus on practical aspects of the neural networks application to modeling and forecasting selected space weather parameters.
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Rajgarhia, Stuti S; Jana, Sadhan C; Chase, George G
2016-08-24
Polymer nanofibers with interpenetrating network (IPN) morphology are used in this work for the development of composite, hydrophobic filter media in conjunction with glass fibers for removal of water droplets from ultralow sulfur diesel (ULSD). The nanofibers are produced from hydrophobic polyvinyl acetate (PVAc) and hydrophilic polyvinylpyrrolidone (PVP) by spinning the polymer solutions using gas jet fiber (GJF) method. The nanofibers coat the individual glass fibers due to polar-polar interactions during the spinning process and render the filter media highly hydrophobic with a water contact angle approaching 150°. The efficiency of the resultant filter media is evaluated in terms of separation of water droplets of average size 20 μm from the suspensions in ULSD.
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Moen, Thomas; Baranski, Matthew; Sonesson, Anna K; Kjøglum, Sissel
2009-01-01
Background Infectious pancreatic necrosis (IPN) is one of the most prevalent and economically devastating diseases in Atlantic salmon (Salmo salar) farming worldwide. The disease causes large mortalities at both the fry- and post-smolt stages. Family selection for increased IPN resistance is performed through the use of controlled challenge tests, where survival rates of sib-groups are recorded. However, since challenge-tested animals cannot be used as breeding candidates, within-family selection is not performed and only half of the genetic variation for IPN resistance is being exploited. DNA markers linked to quantitative trait loci (QTL) affecting IPN resistance would therefore be a powerful selection tool. The aim of this study was to identify and fine-map QTL for IPN-resistance in Atlantic salmon, for use in marker-assisted selection to increase the rate of genetic improvement for this trait. Results A genome scan was carried out using 10 large full-sib families of challenge-tested Atlantic salmon post-smolts and microsatellite markers distributed across the genome. One major QTL for IPN-resistance was detected, explaining 29% and 83% of the phenotypic and genetic variances, respectively. This QTL mapped to the same location as a QTL recently detected in a Scottish Atlantic salmon population. The QTL was found to be segregating in 10 out of 20 mapping parents, and subsequent fine-mapping with additional markers narrowed the QTL peak to a 4 cM region on linkage group 21. Challenge-tested fry were used to show that the QTL had the same effect on fry as on post-smolt, with the confidence interval for QTL position in fry overlapping the confidence interval found in post-smolts. A total of 178 parents were tested for segregation of the QTL, identifying 72 QTL-heterozygous parents. Genotypes at QTL-heterozygous parents were used to determine linkage phases between alleles at the underlying DNA polymorphism and alleles at single markers or multi-marker haplotypes. One four-marker haplotype was found to be the best predictor of QTL alleles, and was successfully used to deduce genotypes of the underlying polymorphism in 72% of the parents of the next generation within a breeding nucleus. A highly significant population-level correlation was found between deduced alleles at the underlying polymorphism and survival of offspring groups in the fry challenge test, parents with the three deduced genotypes (QQ, Qq, qq) having mean offspring mortality rates of 0.13, 0.32, and 0.49, respectively. The frequency of the high-resistance allele (Q) in the population was estimated to be 0.30. Apart from this major QTL, one other experiment-wise significant QTL for IPN-resistance was detected, located on linkage group 4. Conclusion The QTL confirmed in this study represents a case of a major gene explaining the bulk of genetic variation for a presumed complex trait. QTL genotypes were deduced within most parents of the 2005 generation of a major breeding company, providing a solid framework for linkage-based MAS within the whole population in subsequent generations. Since haplotype-trait associations valid at the population level were found, there is also a potential for MAS based on linkage disequilibrium (LD). However, in order to use MAS across many generations without reassessment of linkage phases between markers and the underlying polymorphism, the QTL needs to be positioned with even greater accuracy. This will require higher marker densities than are currently available. PMID:19664221
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Liu, Xin; Xu, Guochun; Wang, Qiangsheng; Hang, Yuhao
2017-01-01
Insect-proof net cultivation (IPN), rice-duck farming (RD), and organic matter return (OM) are important methods to realize sustainable development of rice production. A split-plot field experiment was performed to study the effects of IPN, RD, and OM on the rice yield, dry matter accumulation and N utilization. Results showed that compared to inorganic N fertilizer (IN), wheat straw return, and biogas residue return increased the rice yield by 2.11–4.28 and 4.78–7.67%, respectively, and also improved dry matter and N accumulation after the elongation stage (EG), dry matter and N translocation, and N recovery efficiency (NRE). These results attributed to an increase in leaf SPAD values and net photosynthetic rate (Pn) after the EG. Compared to conventional rice farming (CR), RD promoted the rice yield by 1.52–3.74%, and contributed to higher the leaf photosynthesis, dry matter and N accumulation, dry matter and N translocation, and NRE. IPN decreased the intensity of sun radiation in the nets due to the coverage of the insect-proof nets, which declined the leaf Pn, dry matter accumulation and translocation, N absorption and translocation, and NRE compared to open field cultivation (OFC). The rice yield of IPN were 2.48–4.98% lower than that of OFC. Compared to the interaction between CR and IN, the interaction between RD and OM improved the rice yield by 5.26–9.33%, and increased dry matter and N accumulation after the EG, dry matter and N translocation, and NRE. These results indicated that OM, RD and the interaction between RD and OM could promote dry matter accumulation and N utilization, which was beneficial to improve the rice yield. PMID:28174589
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Photo-excitable hybrid nanocomposites for image-guided photo/TRAIL synergistic cancer therapy.
Lin, Gan; Zhang, Yang; Zhu, Congqing; Chu, Chengchao; Shi, Yesi; Pang, Xin; Ren, En; Wu, Yayun; Mi, Peng; Xia, Haiping; Chen, Xiaoyuan; Liu, Gang
2018-05-22
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) can induce apoptosis in cancer cells without toxicity to normal cells. However, the efficiency is greatly limited by its short half-life and wild resistance in various cancer cells. In this study, we reported a micellar hybrid nanoparticle to carry TRAIL ligand (denoted as IPN@TRAIL) for a novel photo-excited TRAIL therapy. These IPN@TRAIL offered increased TRAIL stability, prolonged half-life and enhanced tumor accumulation, monitored by dual mode imaging. Furthermore, IPN@TRAIL nanocomposites enhanced wrapped TRAIL therapeutic efficiency greatly towards resistant cancer cells by TRAIL nanovectorization. More importantly, when upon external laser, these nanocomposites not only triggered tumor photothermal therapy (PTT), but also upregulated the expression of death receptors (DR4 and DR5), resulting in a greater apoptosis mediated by co-delivered TRAIL ligand. Such photo/TRAIL synergistic effect showed its great killing effects in a controllable manner on TRAIL-resistant A549 tumor model bearing mice. Finally, these nanocomposites exhibited rapid clearance without obvious systemic toxicity. All these features rendered our nanocomposites a promising theranostic platform in cancer therapy. Copyright © 2018 Elsevier Ltd. All rights reserved.
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Grégoire, Geneviève; Dabsie, Firas; Delannée, Mathieu; Akon, Bernadette; Sharrock, Patrick
2010-07-01
Our aim was to investigate the reaction mechanism of formation of the hybrid layer by a HEMA-containing self-etch adhesive and to study fluid filtration, contact angle and interfacial ultrastructure by SEM following a 1 year ageing period. Acidic behaviour and chemical interactions between Silorane System Adhesive and dentine were studied by potentiometric titrations, atomic absorption spectroscopy and infrared spectroscopy. The hydrophilicity of the adhesive was evaluated using the sessile drop method and dentine permeability by hydraulic conductance. The morphological study of the dentine/adhesive system interface was conducted using SEM. The Silorane System Adhesive behaved as a multi-acid with several different pK(a) values. When the adhesive was in contact with dentine, the acid was progressively consumed and calcium ions were released. The acrylate substituted phosphonate bound strongly to apatite crystals. The polyacrylic acid copolymer reacted with calcium ions and formed an interpenetrating polymer network (IPN). Water contact angle measurements showed rapid spreading on primer (angles reached 15 degrees at 30s) and larger contact angles when the Silorane bonding layer was added (from over 60 degrees to 44 degrees ). A thick, homogeneous hybrid layer was observed both initially and after 1 year of ageing, with a corresponding hydraulic conductance of -48.50% initially and -52.07% at 12 months. The Silorane System Adhesive is capable of both dissolving calcium ions and binding to apatite surfaces. The results showed the hydrophilicity of the adhesive, which formed an IPN-like hybrid layer that conserved adequate impermeability over a 1-year period. Copyright 2010 Elsevier Ltd. All rights reserved.
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Sukriti; Sharma, Jitender; Chadha, Amritpal Singh; Pruthi, Vaishali; Anand, Prerna; Bhatia, Jaspreet; Kaith, B S
2017-04-01
Present work reports the synthesis of semi-Interpenetrating Network Polymer (semi-IPN) using Gelatin-Gum xanthan hybrid backbone and polyvinyl alcohol in presence of l-tartaric acid and ammonium persulphate as the crosslinker-initiator system. Reaction parameters were optimized with Response Surface Methodology (RSM) in order to maximize the percent gel fraction of the synthesized sample. Polyvinyl alcohol, l-Tartaric acid, ammonium persulphate, reaction temperature, time and pH of the reaction medium were found to make an impact on the percentage gel fraction obtained. Incorporation of polyvinyl alcohol chains onto hybrid backbone and crosslinking between the different polymer chains were confirmed through techniques like FTIR, SEM-EDX and XRD. Semi-IPN was found to be very efficient in the removal of cationic dyes rhodamine-B (70%) and auramine-O (63%) from a mixture with an adsorbent dose of 700 mg, initial concentration of rhodamine-B 6 mgL -1 and auramine-O 26 mgL -1 , at an time interval of 22-25 h and 30 °C temp. Further to determine the nature of adsorption Langmuir and Freundlich adsorption isotherm models were studied and it was found that Langmuir adsorption isotherm was the best fit model for the removal of mixture of dyes. Kinetic studies for the sorption of dyes favored the reaction mechanism to occur via a pseudo second order pathway with R 2 value about 0.99. Copyright © 2017 Elsevier Ltd. All rights reserved.
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The use of x-ray pulsar-based navigation method for interplanetary flight
NASA Astrophysics Data System (ADS)
Yang, Bo; Guo, Xingcan; Yang, Yong
2009-07-01
As interplanetary missions are increasingly complex, the existing unique mature interplanetary navigation method mainly based on radiometric tracking techniques of Deep Space Network can not meet the rising demands of autonomous real-time navigation. This paper studied the applications for interplanetary flights of a new navigation technology under rapid development-the X-ray pulsar-based navigation for spacecraft (XPNAV), and valued its performance with a computer simulation. The XPNAV is an excellent autonomous real-time navigation method, and can provide comprehensive navigation information, including position, velocity, attitude, attitude rate and time. In the paper the fundamental principles and time transformation of the XPNAV were analyzed, and then the Delta-correction XPNAV blending the vehicles' trajectory dynamics with the pulse time-of-arrival differences at nominal and estimated spacecraft locations within an Unscented Kalman Filter (UKF) was discussed with a background mission of Mars Pathfinder during the heliocentric transferring orbit. The XPNAV has an intractable problem of integer pulse phase cycle ambiguities similar to the GPS carrier phase navigation. This article innovatively proposed the non-ambiguity assumption approach based on an analysis of the search space array method to resolve pulse phase cycle ambiguities between the nominal position and estimated position of the spacecraft. The simulation results show that the search space array method are computationally intensive and require long processing time when the position errors are large, and the non-ambiguity assumption method can solve ambiguity problem quickly and reliably. It is deemed that autonomous real-time integrated navigation system of the XPNAV blending with DSN, celestial navigation, inertial navigation and so on will be the development direction of interplanetary flight navigation system in the future.
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Interplanetary Supply Chain Risk Management
NASA Technical Reports Server (NTRS)
Galluzzi, Michael C.
2018-01-01
Emphasis on KSC ground processing operations, reduced spares up-mass lift requirements and campaign-level flexible path perspective for space systems support as Regolith-based ISM is achieved by; Network modeling for sequencing space logistics and in-space logistics nodal positioning to include feedstock. Economic modeling to assess ISM 3D printing adaption and supply chain risk.
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Limits on Interconnection Bandwidth for On-Board Processing
NASA Technical Reports Server (NTRS)
Lux, James P.
2006-01-01
This viewgraph presentation reviews the constraints, and concerns of spacecraft design, in particular spacecraft instrumentation design and the issues concerning space communication. The advantages and disadvantages of several communication options are reviewed. Ultimately there will be spacecraft communication not between boxes on spacecraft, but between spacecraft. The future of spacecraft communication is interplanetary networks.
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NASA Astrophysics Data System (ADS)
Fushishita, A.; Kuwabara, T.; Kato, C.; Yasue, S.; Bieber, J. W.; Evenson, P.; Da Silva, M. R.; Dal Lago, A.; Schuch, N. J.; Tokumaru, M.; Duldig, M. L.; Humble, J. E.; Sabbah, I.; Jassar, H. K. Al; Sharma, M. M.; Munakata, K.
2010-06-01
We analyze the precursor of a Forbush decrease (FD) observed with the Global Muon Detector Network on 2006 December 14. An intense geomagnetic storm is also recorded during this FD with the peak Kp index of 8+. By using the "two-dimensional map" of the cosmic ray intensity produced after removing the contribution from the diurnal anisotropy, we succeed in extracting clear signatures of the precursor. A striking feature of this event is that a weak loss-cone (LC) signature is first recorded more than a day prior to the storm sudden commencement (SSC) onset. This suggests that the LC precursor appeared only 7 hr after the coronal mass ejection eruption from the Sun, when the interplanetary (IP) shock driven by the interplanetary coronal mass ejection was located at 0.4 AU from the Sun. We find the precursor being successively observed with multiple detectors in the network according to the Earth's spin and confirmed that the precursor continuously exists in space. The long lead time (15.6 hr) of this precursor which is almost twice the typical value indicates that the interplanetary magnetic field (IMF) was more quiet in this event than a typical power spectrum assumed for the IMF turbulence. The amplitude (-6.45%) of the LC anisotropy at the SSC onset is more than twice the FD size, indicating that the maximum intensity depression behind the IP shock is much larger than the FD size recorded at the Earth in this event. We also find the excess intensity from the sunward IMF direction clearly observed during ~10 hr preceding the SSC onset. It is shown that this excess intensity is consistent with the measurement of the particles accelerated by the head-on collisions with the approaching shock. This is the first detailed observation of the precursor due to the shock reflected particles with muon detectors.
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Ullrich, Lauren; Dumanis, Sonya B; Evans, Tanya M; Jeannotte, Alexis M; Leonard, Carrie; Rozzi, Summer J; Taylor, Caitlin M; Gale, Karen; Kanwal, Jagmeet S; Maguire-Zeiss, Kathleen A; Wolfe, Barry B; Forcelli, Patrick A
2014-01-01
A key facet of professional development is the formation of professional identity. At its most basic level, professional identity for a scientist centers on mastery of a discipline and the development of research skills during doctoral training. To develop a broader understanding of professional identity in the context of doctoral training, the Carnegie Initiative on the Doctorate (CID) ran a multi-institutional study from 2001 to 2005. A key outcome of the CID was the development of the concept of 'stewards of the discipline'. The Interdisciplinary Program in Neuroscience (IPN) at Georgetown University participated in CID from 2003 to 2005. Here, we describe the IPN and highlight the programmatic developments resulting from participation in the CID. In particular, we emphasize programmatic activities that are designed to promote professional skills in parallel with scientific development. We describe activities in the domains of leadership, communication, teaching, public outreach, ethics, collaboration, and mentorship. Finally, we provide data that demonstrate that traditional metrics of academic success are not adversely affected by the inclusion of professional development activities in the curricula. By incorporating these seven 'professional development' activities into the required coursework and dissertation research experience, the IPN motivates students to become stewards of the discipline.
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DOE Office of Scientific and Technical Information (OSTI.GOV)
Clarke, P.B.; Hamill, G.S.; Nadi, N.S.
1986-09-15
The cholinergic innervation of the interpeduncular nucleus (IPN) is wholly extrinsic and is greatly attenuated by bilateral habenular destruction. We describe changes in the labeling of putative nicotinic receptors within this nucleus at 3, 5, or 11 days after bilateral habenular lesions. Adjacent tissue sections of the rat IPN were utilized for /sup 3/H-nicotine and /sup 125/I-alpha-bungarotoxin (/sup 125/I-BTX) receptor autoradiography. Compared to sham-operated controls, habenular destruction significantly reduced autoradiographic /sup 3/H-nicotine labeling in rostral (-25%), intermediate (-13%), and lateral subnuclei (-36%). Labeling in the central subnucleus was unchanged. Loss of labeling was maximal at the shortest survival time (3more » days) and did not change thereafter. In order to establish whether this loss was due to a reduction in the number or the affinity of /sup 3/H-nicotine-binding sites, a membrane assay was performed on microdissected IPN tissue from rats that had received surgery 3 days previously. Bilateral habenular lesions produced a 35% reduction of high-affinity /sup 3/H-nicotine-binding sites, with no change in binding affinity. Bilateral habenular lesions reduced /sup 125/I-BTX labeling in the intermediate subnuclei, and a slight increase occurred in the rostral subnucleus. In the lateral subnuclei, /sup 125/I-BTX labeling was significantly reduced (27%) at 3 days but not at later survival times. In view of the known synaptic morphology of the habenulointerpeduncular tract, it is concluded that a subpopulation of /sup 3/H-nicotine binding sites within the IPN is located on afferent axons and/or terminals. This subpopulation, located within rostral, intermediate, and lateral subnuclei, may correspond to presynaptic nicotinic cholinergic receptors. Sites that bind /sup 125/I-BTX may include a presynaptic subpopulation located in the lateral and possibly the intermediate subnuclei.« less
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Sharma, Deepesh; Jakkampudi, Aparna; Reddy, Ratnakar; Reddy, Panyala Balakumar; Patil, Aasish; Murthy, H V V; Rao, G Venkat; Reddy, D Nageshwar; Talukdar, Rupjyoti
2017-12-01
This paper reports preliminary data of an ongoing study that evaluates the association of systemic inflammatory response (SIRS) with early severe acute pancreatitis (ESAP) and compensatory anti-inflammatory response syndrome (characterized by HLA-DR down-regulation) with infected pancreatic necrosis (IPN). Consecutive patients presenting within 72 h of symptom onset with organ dysfunction and/or local complications were included. Following parameters were recorded: demographics, etiology, SIRS, APACHE II, creatinine, BUN. Circulating IL-8, IL-6, IL-10, TNF-alpha concentrations and expression of HLA-DR and IL-10 by qRT-PCR in PBMCs were measured. Strength of associations of cytokine concentration and HLA-DR/IL-10 expression with outcomes was expressed as Hedges' G and relative risk (95% CI). Twenty-eight patients (10 MSAP; 18 SAP) fulfilled inclusion criteria. Twelve patients had ESAP and eight presented with organ failure. Admission SIRS worsened in eight (28.6%) patients over 48 h. Sixteen (57.1%) patients developed primary IPN. Twenty-one (75%) patients had HLA-DR down-regulation during the first week, which persisted to the second week in 12 (42.9%) patients. IL-8, IL-6, and TNF-α progressively increased from healthy controls to MAP to MSAP to SAP. IL-6 and TNF-α was higher in the patients who developed ESAP (p = 0.01 and 0.05, respectively). Patients who died within the first week also had a significantly elevated concentration of IL-6 and TNF-α (p = 0.02 and 0.01, respectively). The relative risk (95% CI) of developing primary IPN with persistent HLA-DR down-regulation till the second week of illness was 11.3 (1.6-82.4; p = 0.01). Our study objectively demonstrates significant association of ESAP and early mortality with primary cytokine response, and development of IPN with persistent HLA-DR down-regulation.
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Automated Consultation for the Diagnosis of Interplanetary Telecommunications
NASA Technical Reports Server (NTRS)
Quan, A. G.; Schwuttke, U. M.; Herstein, J. S.; Spagnuolo, J. S.; Burleigh, S.
1995-01-01
SHARP (Spacecraft Health Automated Reasoning Program) is a knowledge-based system for the diagnosis of problems in NASA's Deep Space Network (DSN) telecommunications system. This system provides the means of communication between a spacecraft and operations personnel at Jet Propulsion Laboratory. SHARP analyzes problems that occur in both the on-board spacecraft telecom subsystem, and the DSN.
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NASA Technical Reports Server (NTRS)
Miller, R. B.
1974-01-01
The Tracking and Data System supported the deep space phases of the Pioneer 6, 7, 8, and 9 missions, with two spacecraft in an inward trajectory and two spacecraft in an outward trajectory from the earth in heliocentric orbits. During the period of this report, scientific instruments aboard each of the spacecraft continued to register information relative to interplanetary particles and fields, and radiometric data generated by the network continued to contribute to knowledge of the celestial mechanics of the solar system. In addition, to network support activity detail, network performance and special support activities are covered.
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NASA Technical Reports Server (NTRS)
Renzetti, N. A.; Siegmeth, A. J.
1973-01-01
The Tracking and Data System supported the deep space phases of the Pioneer 6, 7, 8, and 9 missions, with two spacecraft in an inward trajectory and two spacecraft in an outward trajectory from the earth in heliocentric orbits. Scientific instruments aboard each of the spacecraft continued to register information relative to interplanetary particles and fields, and radio metric data generated by the network continued to improve our knowledge of the celestial mechanics of the solar system. In addition to network support activity detail, network performance and special support activities are covered.
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Timing and Causality in the Generation of Learned Eyelid Responses
Sánchez-Campusano, Raudel; Gruart, Agnès; Delgado-García, José M.
2011-01-01
The cerebellum-red nucleus-facial motoneuron (Mn) pathway has been reported as being involved in the proper timing of classically conditioned eyelid responses. This special type of associative learning serves as a model of event timing for studying the role of the cerebellum in dynamic motor control. Here, we have re-analyzed the firing activities of cerebellar posterior interpositus (IP) neurons and orbicularis oculi (OO) Mns in alert behaving cats during classical eyeblink conditioning, using a delay paradigm. The aim was to revisit the hypothesis that the IP neurons (IPns) can be considered a neuronal phase-modulating device supporting OO Mns firing with an emergent timing mechanism and an explicit correlation code during learned eyelid movements. Optimized experimental and computational tools allowed us to determine the different causal relationships (temporal order and correlation code) during and between trials. These intra- and inter-trial timing strategies expanding from sub-second range (millisecond timing) to longer-lasting ranges (interval timing) expanded the functional domain of cerebellar timing beyond motor control. Interestingly, the results supported the above-mentioned hypothesis. The causal inferences were influenced by the precise motor and pre-motor spike timing in the cause-effect interval, and, in addition, the timing of the learned responses depended on cerebellar–Mn network causality. Furthermore, the timing of CRs depended upon the probability of simulated causal conditions in the cause-effect interval and not the mere duration of the inter-stimulus interval. In this work, the close relation between timing and causality was verified. It could thus be concluded that the firing activities of IPns may be related more to the proper performance of ongoing CRs (i.e., the proper timing as a consequence of the pertinent causality) than to their generation and/or initiation. PMID:21941469
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NASA Technical Reports Server (NTRS)
Royden, H. N.; Green, D. W.; Walson, G. R.
1981-01-01
Faraday-rotation data from the linearly polarized 137-MHz beacons of the ATS-1, SIRIO, and Kiku-2 geosynchronous satellites are used to determine the ionospheric corrections to the range and Doppler data for interplanetary spacecraft navigation. The JPL operates the Deep Space Network of tracking stations for NASA; these stations monitor Faraday rotation with dual orthogonal, linearly polarized antennas, Teledyne polarization tracking receivers, analog-to-digital converter/scanners, and other support equipment. Computer software examines the Faraday data, resolves the pi ambiguities, constructs a continuous Faraday-rotation profile and converts the profile to columnar zenith total electron content at the ionospheric reference point; a second program computes the line-of-sight ionospheric correction for each pass of the spacecraft over each tracking complex. Line-of-sight ionospheric electron content using mapped Faraday-rotation data is compared with that using dispersive Doppler data from the Voyager spacecraft; a difference of about 0.4 meters, or 5 x 10 to the 16th electrons/sq m is obtained. The technique of determining the electron content of interplanetary plasma by subtraction of the ionospheric contribution is demonstrated on the plasma torus surrounding the orbit of Io.
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Delay Tolerant Networking on NASA's Space Communication and Navigation Testbed
NASA Technical Reports Server (NTRS)
Johnson, Sandra; Eddy, Wesley
2016-01-01
This presentation covers the status of the implementation of an open source software that implements the specifications developed by the CCSDS Working Group. Interplanetary Overlay Network (ION) is open source software and it implements specifications that have been developed by two international working groups through IETF and CCSDS. ION was implemented on the SCaN Testbed, a testbed located on an external pallet on ISS, by the GRC team. The presentation will cover the architecture of the system, high level implementation details, and issues porting ION to VxWorks.
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NASA Technical Reports Server (NTRS)
Barton, W. R.; Miller, R. B.
1975-01-01
The tracking and data system support of the planning, testing, launch, near-earth, and deep space phases of the Pioneer 11 Jupiter Mission are described, including critical phases of spacecraft flight and guidance. Scientific instruments aboard the spacecraft registered information relative to interplanetary particles and fields. Knowledge of the celestial mechanics of the solar system was improved through radiometric data gathering. Network performance, details of network support activity, and special support activities are discussed.
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Stress Analysis on Screw Thread
1984-08-01
PFRAD) EJX=BMJE)IA I’ (BASIC) EJN=EJX- .O5*P ITCH IPN= EdX -HE2 EPX=IPN-.0O8*BMJDIA**5 EPN=EPX- ( .030*PITCH+ .006*BMJDIA*5) IMN=EJX-2. *HE2 IF(N.LE. 10...EQ. 4) THEN ,-ERSTHz ’BUT CALL TCLASS C,,ALL d2dHIJT ENDIF CALL Fr )() WMTH1v(A~,H~.)?, PRESSURE FACE (PF ANGLE): ’PFANG A 36 WRITE(l,’(A22,F5.2...IJA.W,.O. .Ji. (IJA.LE.ILJX.AND.IJA.GE.IJN)) Gl=IJX A68 W3(.66*/3. 2. FR )*.)5 KAIN:1.+((K2-1.)*W2*WQ/((K2-1. )**.2+W2**2.)**.5)*COS *(2.*PI/3..APFRAD
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Global Survey Method for the World Network of Neutron Monitors
NASA Astrophysics Data System (ADS)
Belov, A. V.; Eroshenko, E. A.; Yanke, V. G.; Oleneva, V. A.; Abunina, M. A.; Abunin, A. A.
2018-05-01
One of the variants of the global survey method developed and used for many years at the Institute of Terrestrial Magnetism, Ionosphere, and Radio Wave Propagation of the Russian Academy of Sciences is described. Data from the world network of neutron monitors for every hour from July 1957 to the present has been processed by this method. A consistent continuous series of hourly characteristics of variation of the density and vector anisotropy of cosmic rays with a rigidity of 10 GV is obtained. A database of Forbush decreases in galactic cosmic rays caused by large-scale disturbances of the interplanetary medium for more than half a century has been created based on this series. The capabilities of the database make it possible to perform a correlation analysis of various parameters of the space environment (characteristics of the Sun, solar wind, and interplanetary magnetic field) with the parameters of cosmic rays and to study their interrelationships in the solar-terrestrial space. The features of reception coefficients for different stations are considered, which allows the transition from variations according to ground measurements to variations of primary cosmic rays. The advantages and disadvantages of this variant of the global survey method and the opportunities for its development and improvement are assessed. The developed method makes it possible to minimize the problems of the network of neutron monitors and to make significant use of its advantages.
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The gravitational wave experiment
NASA Technical Reports Server (NTRS)
Bertotti, B.; Ambrosini, R.; Asmar, S. W.; Brenkle, J. P.; Comoretto, G.; Giampieri, G.; Less, L.; Messeri, A.; Wahlquist, H. D.
1992-01-01
Since the optimum size of a gravitational wave detector is the wave length, interplanetary dimensions are needed for the mHz band of interest. Doppler tracking of Ulysses will provide the most sensitive attempt to date at the detection of gravitational waves in the low frequency band. The driving noise source is the fluctuations in the refractive index of interplanetary plasma. This dictates the timing of the experiment to be near solar opposition and sets the target accuracy for the fractional frequency change at 3.0 x 10 exp -14 for integration times of the order of 1000 sec. The instrumentation utilized by the experiment is distributed between the radio systems on the spacecraft and the seven participating ground stations of the Deep Space Network and Medicina. Preliminary analysis is available of the measurements taken during the Ulysses first opposition test.
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The MEXART ips observations in route to the next solar maximum
NASA Astrophysics Data System (ADS)
Carrillo-Vargas, Armando; Gonzalez-Esparza, Americo; Andrade, Ernesto; Perez-Enriquez, Roman; Aguilar-Rodriguez, Ernesto; Casillas-Perez, Gilberto; Jeyakumar, Solai; Kurtz, Stanley; Sierra, Pablo; Vazquez, Samuel
We report the status of the Mexican Array Radio Telescope (MEXART) in preparation for the next solar maximum. During this epoch, the MEXART will be one of the four dedicated radio telescopes (with the ORT in India; STEL in Japan; and MWA in Australia) to track large-scale structures in the solar wind using the interplanetary scintillation (IPS) technique. This network of IPS observatories would produce, for the first time four g maps of the sky showing the size and shape of disturbances between the Sun and the Earth. We describe the operation and current observations of the first IPS radio sources at 140 MHz detected by the MEXART. These observations use a plane dipole array of 1024 elements (16 lines with 64 dipoles each one), feeding a Butler matrix of 16x16 ports. This system generates a 16 lobes at fixed declinations covering 120 degrees (from 40 degrees South to 80 degrees North). The beam fan uses the Earth's rotation to cover the whole sky. The observations that will be made with the network of observatories of interplanetary flashing will complement the observations of other observatories, instruments in situ, space probes, satellite, among others.
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Mexican Space Weather Service (SCiESMEX)
NASA Astrophysics Data System (ADS)
Gonzalez-Esparza, J. A.; De la Luz, V.; Corona-Romero, P.; Mejia-Ambriz, J. C.; Gonzalez, L. X.; Sergeeva, M. A.; Romero-Hernandez, E.; Aguilar-Rodriguez, E.
2017-01-01
Legislative modifications of the General Civil Protection Law in Mexico in 2014 included specific references to space hazards and space weather phenomena. The legislation is consistent with United Nations promotion of international engagement and cooperation on space weather awareness, studies, and monitoring. These internal and external conditions motivated the creation of a space weather service in Mexico. The Mexican Space Weather Service (SCiESMEX in Spanish) (www.sciesmex.unam.mx) was initiated in October 2014 and is operated by the Institute of Geophysics at the Universidad Nacional Autonoma de Mexico (UNAM). SCiESMEX became a Regional Warning Center of the International Space Environment Services (ISES) in June 2015. We present the characteristics of the service, some products, and the initial actions for developing a space weather strategy in Mexico. The service operates a computing infrastructure including a web application, data repository, and a high-performance computing server to run numerical models. SCiESMEX uses data of the ground-based instrumental network of the National Space Weather Laboratory (LANCE), covering solar radio burst emissions, solar wind and interplanetary disturbances (by interplanetary scintillation observations), geomagnetic measurements, and analysis of the total electron content (TEC) of the ionosphere (by employing data from local networks of GPS receiver stations).
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Anxiety and nicotine dependence: Emerging role of the habenulo-interpeduncular axis
Molas, Susanna; DeGroot, Steven; Zhao-Shea, Rubing; Tapper, Andrew R.
2016-01-01
While innovative modern neuroscience approaches have aided in discerning brain circuitry underlying negative emotional behaviors including fear and anxiety responses, how these circuits are recruited in normal and pathological conditions remains poorly understood. Recently, genetic tools that selectively manipulate single neuronal populations have uncovered an understudied circuit, the medial habenula (mHb)-interpeduncular (IPN) axis, that modulates basal negative emotional responses. Interestingly, the mHb-IPN pathway also represents an essential circuit that signals heightened anxiety induced by nicotine withdrawal. Insights into how this circuit inter-connects with regions more classically associated with anxiety and how chronic nicotine exposure induces neuroadaptations resulting in an anxiogenic state, may thereby provide novel strategies and molecular targets for therapies that facilitate smoking cessation, as well as, anxiety relief. PMID:27890353
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BPTAP: A New Approach to IP over DTN
NASA Technical Reports Server (NTRS)
Tsao, Philip; Nguyen, Sam
2012-01-01
Traditional Internet protocols have been widely deployed for a variety of applications. However such protocols generally perform poorly in situations in which, round trip delays are very large (interplanetary distances) or . persistent connectivity is not always available (widely dispersed MANET). Delay/Disruption Tolerant Network (DTN) technology was invented to address these issues: (1) . Relay nodes "take custody" of blocks of network traffic on a hop-by -hop basis and retransmit them in cases of expected or unexpected link outage (2) Bundle lifetime may be configured for long round trip light times. BPTAP is novel by encapsulating Ethernet frames in BP
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Chang, Ching-Hsien; Liu, Hsia-Wei; Huang, Ching-Cheng
2014-01-01
A series of designed drug-release systems were prepared and established for clear moisture healing. These systems were designed to have an interpenetrating polymer network (IPN) structure, which contained a breathable polyurethane film, hydrocolloidlayer, and polyacrylate adhesive layer. Breathable polyurethane film (2000 g/m(2)/24 hr) with high moisture permeability was employed as a base for new drug-release systems or wound dressings. All drug-release systems having a polyurethane film-backed hydrocolloid acrylated adhesive layer showed an increase of water uptakes with increasing time. After 114 hours, high water uptakes of drug-release systems with 20% hydrocolloid components were observed in the values of 160, 1100, and 1870% for different additional hydrocolloid components of carboxymethylcellulose, sodium alginate, and carbomer U10, respectively. New drug-release systems of polyurethane film-backed hydrocolloid/adhesive layers could be designed and established for wound care managements.
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Anxiety and Nicotine Dependence: Emerging Role of the Habenulo-Interpeduncular Axis.
Molas, Susanna; DeGroot, Steven R; Zhao-Shea, Rubing; Tapper, Andrew R
2017-02-01
While innovative modern neuroscience approaches have aided in discerning brain circuitry underlying negative emotional behaviors including fear and anxiety responses, how these circuits are recruited in normal and pathological conditions remains poorly understood. Recently, genetic tools that selectively manipulate single neuronal populations have uncovered an understudied circuit, the medial habenula (mHb)-interpeduncular (IPN) axis, that modulates basal negative emotional responses. Interestingly, the mHb-IPN pathway also represents an essential circuit that signals heightened anxiety induced by nicotine withdrawal. Insights into how this circuit interconnects with regions more classically associated with anxiety, and how chronic nicotine exposure induces neuroadaptations resulting in an anxiogenic state, may thereby provide novel strategies and molecular targets for therapies that facilitate smoking cessation, as well as for anxiety relief. Copyright © 2016 Elsevier Ltd. All rights reserved.
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Role of intermediate state in the excited state dynamics of highly efficient TADF molecules
NASA Astrophysics Data System (ADS)
Hosokai, Takuya; Matsuzaki, Hiroyuki; Furube, Akihiro; Tokumaru, Katsumi; Tsutsui, Tetsuo; Nakanotani, Hajime; Yahiro, Masayuki; Adachi, Chihaya
2016-09-01
We hereby report the results of our direct investigation into the excited-state dynamics of thermally activated delayed fluorescence (TADF) molecules in solution using pump-probe transient absorption spectroscopy (TAS). We found that the charge-transfer (CT) state commonly stated for TADF molecules encompasses two forms: localized and delocalized CT states. A highly efficient TADF molecule, 4CzIPN [Uoyama et al., Nature, 492, 234-238 (2012)], showed both the localized and delocalized CT states, while an inefficient TADF molecule, 2CzPN, exhibited only a localized CT state. By analyzing the time profile of triplet species observed in TAS, we propose that the reverse intersystem crossing (RISC) of 4CzIPN occurs via a mutual interaction in multiple energy levels of localized neutral and CT states, and delocalized CT states.
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DOE Office of Scientific and Technical Information (OSTI.GOV)
Banerjee, Santanu, E-mail: sbanerje@ipr.res.in; Mishra, K.; Zushi, H.
Fluctuations are measured in the edge and scrape-off layer (SOL) of QUEST using fast visible imaging diagnostic. Electron cyclotron wave injection in the Ohmic plasma features excitation of low frequency coherent fluctuations near the separatrix and enhanced cross-field transport. Plasma shifts from initial high field side limiter bound (inboard limited, IL) towards inboard poloidal null (IPN) configuration with steepening of the density profile at the edge. This may have facilitated the increased edge and SOL fluctuation activities. Observation of the coherent mode, associated plasma flow, and particle out-flux, for the first time in the IPN plasma configuration in a sphericalmore » tokamak may provide further impetus to the edge and SOL turbulence studies in tokamaks.« less
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Wear rates of artificial denture teeth opposed by natural dentition.
Douglas, W H; Delong, R; Pintado, M R; Latta, M A
1993-01-01
The wear rate of polymeric or composite-based artificial denture teeth on fixed, removable and implant prostheses is important in the maintenance of cuspal form, masticatory efficiency and occlusal stability. A servo-hydraulic based artificial mouth in which an occlusion was established between artificial denture teeth, and the palatal cusp of a human maxillary third molar was established and used to assess the wear resistance of 5 artificial denture tooth materials. Volumetric wear was determined for Dentsply Trublend SLM, Dentsply IPN, Vita Vitapan, Ivoclar Orthotyp and Ivoclar Orthosit denture teeth. Scanning electron microscopy was also done to assess the textural character of the wear facets of each denture tooth sample. The lowest volume loss was observed for Trublend SLM followed by IPN, Orthotyp, Vitapan and Orthosit. Textural assessment of the materials was consistent with the objective wear data.
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Cholinergic left-right asymmetry in the habenulo-interpeduncular pathway.
Hong, Elim; Santhakumar, Kirankumar; Akitake, Courtney A; Ahn, Sang Jung; Thisse, Christine; Thisse, Bernard; Wyart, Claire; Mangin, Jean-Marie; Halpern, Marnie E
2013-12-24
The habenulo-interpeduncular pathway, a highly conserved cholinergic system, has emerged as a valuable model to study left-right asymmetry in the brain. In larval zebrafish, the bilaterally paired dorsal habenular nuclei (dHb) exhibit prominent left-right differences in their organization, gene expression, and connectivity, but their cholinergic nature was unclear. Through the discovery of a duplicated cholinergic gene locus, we now show that choline acetyltransferase and vesicular acetylcholine transporter homologs are preferentially expressed in the right dHb of larval zebrafish. Genes encoding the nicotinic acetylcholine receptor subunits α2 and β4 are transcribed in the target interpeduncular nucleus (IPN), suggesting that the asymmetrical cholinergic pathway is functional. To confirm this, we activated channelrhodopsin-2 specifically in the larval dHb and performed whole-cell patch-clamp recording of IPN neurons. The response to optogenetic or electrical stimulation of the right dHb consisted of an initial fast glutamatergic excitatory postsynaptic current followed by a slow-rising cholinergic current. In adult zebrafish, the dHb are divided into discrete cholinergic and peptidergic subnuclei that differ in size between the left and right sides of the brain. After exposing adults to nicotine, fos expression was activated in subregions of the IPN enriched for specific nicotinic acetylcholine receptor subunits. Our studies of the newly identified cholinergic gene locus resolve the neurotransmitter identity of the zebrafish habenular nuclei and reveal functional asymmetry in a major cholinergic neuromodulatory pathway of the vertebrate brain.
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NASA Technical Reports Server (NTRS)
Siegmeth, A. J.; Purdue, R. E.; Ryan, R. E.
1973-01-01
The tracking and data system support of the launch, near-earth, and deep space phases of the Pioneer 10 mission, which sent a Pioneer spacecraft into a flyby of Jupiter that would eventually allow the spacecraft to escape the solar system is discussed. The support through the spacecraft's second trajectory correction is reported. During this period, scientific instruments aboard the spacecraft registered information relative to interplanetary particles and fields, and radiometric data generated by the network continued to improve knowledge of the celestial mechanics of the solar system. In addition to network support activity detail, network performance and special support activities are covered.
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Interplanetary Overlay Network Bundle Protocol Implementation
NASA Technical Reports Server (NTRS)
Burleigh, Scott C.
2011-01-01
The Interplanetary Overlay Network (ION) system's BP package, an implementation of the Delay-Tolerant Networking (DTN) Bundle Protocol (BP) and supporting services, has been specifically designed to be suitable for use on deep-space robotic vehicles. Although the ION BP implementation is unique in its use of zero-copy objects for high performance, and in its use of resource-sensitive rate control, it is fully interoperable with other implementations of the BP specification (Internet RFC 5050). The ION BP implementation is built using the same software infrastructure that underlies the implementation of the CCSDS (Consultative Committee for Space Data Systems) File Delivery Protocol (CFDP) built into the flight software of Deep Impact. It is designed to minimize resource consumption, while maximizing operational robustness. For example, no dynamic allocation of system memory is required. Like all the other ION packages, ION's BP implementation is designed to port readily between Linux and Solaris (for easy development and for ground system operations) and VxWorks (for flight systems operations). The exact same source code is exercised in both environments. Initially included in the ION BP implementations are the following: libraries of functions used in constructing bundle forwarders and convergence-layer (CL) input and output adapters; a simple prototype bundle forwarder and associated CL adapters designed to run over an IPbased local area network; administrative tools for managing a simple DTN infrastructure built from these components; a background daemon process that silently destroys bundles whose time-to-live intervals have expired; a library of functions exposed to applications, enabling them to issue and receive data encapsulated in DTN bundles; and some simple applications that can be used for system checkout and benchmarking.
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NASA Astrophysics Data System (ADS)
Carvalho, Diego D. B.; Akkus, Zeynettin; Bosch, Johan G.; van den Oord, Stijn C. H.; Niessen, Wiro J.; Klein, Stefan
2014-03-01
In this work, we investigate nonrigid motion compensation in simultaneously acquired (side-by-side) B-mode ultrasound (BMUS) and contrast enhanced ultrasound (CEUS) image sequences of the carotid artery. These images are acquired to study the presence of intraplaque neovascularization (IPN), which is a marker of plaque vulnerability. IPN quantification is visualized by performing the maximum intensity projection (MIP) on the CEUS image sequence over time. As carotid images contain considerable motion, accurate global nonrigid motion compensation (GNMC) is required prior to the MIP. Moreover, we demonstrate that an improved lumen and plaque differentiation can be obtained by averaging the motion compensated BMUS images over time. We propose to use a previously published 2D+t nonrigid registration method, which is based on minimization of pixel intensity variance over time, using a spatially and temporally smooth B-spline deformation model. The validation compares displacements of plaque points with manual trackings by 3 experts in 11 carotids. The average (+/- standard deviation) root mean square error (RMSE) was 99+/-74μm for longitudinal and 47+/-18μm for radial displacements. These results were comparable with the interobserver variability, and with results of a local rigid registration technique based on speckle tracking, which estimates motion in a single point, whereas our approach applies motion compensation to the entire image. In conclusion, we evaluated that the GNMC technique produces reliable results. Since this technique tracks global deformations, it can aid in the quantification of IPN and the delineation of lumen and plaque contours.
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NASA Technical Reports Server (NTRS)
Ricker, George R.
1990-01-01
The Energetic Transient Array (ETA) is a concept for a dedicated interplanetary network of about 40 microsatellites ('space buoys') deployed in an about 1 AU radius solar orbit for the observation of cosmic gamma ray bursts (GRBs). Such a network is essential for the determination of highly accurate (about 0.1 arcsec) error boxes for GRBs. For each of about 100 bursts which would be detectable per year of observation by such a network, high resolution spectra could be obtained through the use of passively-cooled Ge gamma-ray detectors. Stabilization of each microsatellite would be achieved by a novel technique based on the radiation pressure exerted on 'featherable' solar paddles. It should be possible to have a fully functional array of satellites in place before the end of the decade for a total cost of about $20M, exclusive of launcher fees.
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Protocol for a Delay-Tolerant Data-Communication Network
NASA Technical Reports Server (NTRS)
Torgerson, Jordan; Hooke, Adrian; Burleigh, Scott; Fall, Kevin
2004-01-01
As its name partly indicates, the Delay-Tolerant Networking (DTN) Bundle Protocol is a protocol for delay-tolerant transmission of data via communication networks. This protocol was conceived as a result of studies of how to adapt Internet protocols so that Internet-like services could be provided across interplanetary distances in support of deep-space exploration. The protocol, and software to implement the protocol, is being developed in collaboration among experts at NASA's Jet Propulsion Laboratory and other institutions. No current Internet protocols can accommodate long transmission delay times or intermittent link connectivity. The DTN Bundle Protocol represents a departure from the standard Internet assumption that a continuous path is available from a host computer to a client computer: It provides for routing of data through networks that may be disjointed and may be characterized by long transmission delays. In addition to networks that include deepspace communication links, examples of such networks include terrestrial ones within which branches are temporarily disconnected. The protocol is based partly on the definition of a message-based overlay above the transport layers of the networks on which it is hosted.
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Security Analysis of DTN Architecture and Bundle Protocol Specification for Space-Based Networks
NASA Technical Reports Server (NTRS)
Ivancic, William D.
2009-01-01
A Delay-Tolerant Network (DTN) Architecture (Request for Comment, RFC-4838) and Bundle Protocol Specification, RFC-5050, have been proposed for space and terrestrial networks. Additional security specifications have been provided via the Bundle Security Specification (currently a work in progress as an Internet Research Task Force internet-draft) and, for link-layer protocols applicable to Space networks, the Licklider Transport Protocol Security Extensions. This document provides a security analysis of the current DTN RFCs and proposed security related internet drafts with a focus on space-based communication networks, which is a rather restricted subset of DTN networks. Note, the original focus and motivation of DTN work was for the Interplanetary Internet . This document does not address general store-and-forward network overlays, just the current work being done by the Internet Research Task Force (IRTF) and the Consultative Committee for Space Data Systems (CCSDS) Space Internetworking Services Area (SIS) - DTN working group under the DTN and Bundle umbrellas. However, much of the analysis is relevant to general store-and-forward overlays.
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Hybrid Mobile Communication Networks for Planetary Exploration
NASA Technical Reports Server (NTRS)
Alena, Richard; Lee, Charles; Walker, Edward; Osenfort, John; Stone, Thom
2007-01-01
A paper discusses the continuing work of the Mobile Exploration System Project, which has been performing studies toward the design of hybrid communication networks for future exploratory missions to remote planets. A typical network could include stationary radio transceivers on a remote planet, mobile radio transceivers carried by humans and robots on the planet, terrestrial units connected via the Internet to an interplanetary communication system, and radio relay transceivers aboard spacecraft in orbit about the planet. Prior studies have included tests on prototypes of these networks deployed in Arctic and desert regions chosen to approximate environmental conditions on Mars. Starting from the findings of the prior studies, the paper discusses methods of analysis, design, and testing of the hybrid communication networks. It identifies key radio-frequency (RF) and network engineering issues. Notable among these issues is the study of wireless LAN throughput loss due to repeater use, RF signal strength, and network latency variations. Another major issue is that of using RF-link analysis to ensure adequate link margin in the face of statistical variations in signal strengths.
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Interplanetary Physics Laboratory (IPL): A concept for an interplanetary mission in the mid-eighties
NASA Technical Reports Server (NTRS)
Burlaga, L. F.; Ogilvie, K. W.; Feldman, W.
1977-01-01
A concept for a near-earth interplanetary mission in the mid-eighties is described. The proposed objectives would be to determine the composition of the interplanetary constituents and its dependence on source-conditions and to investigate energy and momentum transfer processes in the interplanetary medium. Such a mission would accomplish three secondary objectives: (1) provide a baseline for deep space missions, (2) investigate variations of the solar wind with solar activity, and (3) provide input functions for magnetospheric studies.
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NASA Technical Reports Server (NTRS)
Donnelly, H.
1983-01-01
Before discussing Deep Space Network receivers, a brief description of the functions of receivers and how they interface with other elements of the Network is presented. Different types of receivers are used in the Network for various purposes. The principal receiver type is used for telemetry and tracking. This receiver provides the capability, with other elements of the Network, to track the space probe utilizing Doppler and range measurements, and to receive telemetry, including both scientific data from the onboard experiments and engineering data pertaining to the health of the probe. Another type of receiver is used for radio science applications. This receiver measures phase perturbations on the carrier signal to obtain information on the composition of solar and planetary atmospheres and interplanetary space. A third type of receiver utilizes very long baseline interferometry (VLBI) techniques for both radio science and spacecraft navigation data. Only the telemetry receiver is described in detail in this document. The integration of the Receiver-Exciter subsystem with other portions of the Deep Space Network is described.
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Interplanetary field and plasma during initial phase of geomagnetic storms
NASA Technical Reports Server (NTRS)
Patel, V. L.; Wiskerchen, M. J.
1975-01-01
A study has been conducted of a large number of geomagnetic storms occurring during the period from 1966 to 1970. Questions of data selection are discussed and the large-scale interplanetary magnetic field during the initial phase is examined. Small-scale interplanetary fields during the initial phase are also considered, taking into account important features of small-scale variations in the interplanetary field and plasma for three storms. Details concerning 23 geomagnetic storms and the interplanetary magnetic field are presented in a table. A study of the initial phase of these storms indicates that in most of these events, the solar-ecliptic Z component of the interplanetary magnetic field turns southward when the main phase decrease begins.
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FreeTure: A Free software to capTure meteors for FRIPON
NASA Astrophysics Data System (ADS)
Audureau, Yoan; Marmo, Chiara; Bouley, Sylvain; Kwon, Min-Kyung; Colas, François; Vaubaillon, Jérémie; Birlan, Mirel; Zanda, Brigitte; Vernazza, Pierre; Caminade, Stephane; Gattecceca, Jérôme
2014-02-01
The Fireball Recovery and Interplanetary Observation Network (FRIPON) is a French project started in 2014 which will monitor the sky, using 100 all-sky cameras to detect meteors and to retrieve related meteorites on the ground. There are several detection software all around. Some of them are proprietary. Also, some of them are hardware dependent. We present here the open source software for meteor detection to be installed on the FRIPON network's stations. The software will run on Linux with gigabit Ethernet cameras and we plan to make it cross platform. This paper is focused on the meteor detection method used for the pipeline development and the present capabilities.
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Large-scale properties of the interplanetary magnetic field
NASA Technical Reports Server (NTRS)
Schatten, K. H.
1972-01-01
Early theoretical work of Parker is presented along with the observational evidence supporting his Archimedes spiral model. Variations present in the interplanetary magnetic field from the spiral angle are related to structures in the solar wind. The causes of these structures are found to be either nonuniform radial solar wind flow or the time evolution of the photospheric field. Coronal magnetic models are related to the connection between the solar magnetic field and the interplanetary magnetic field. Direct extension of the solar field-magnetic nozzle controversy is discussed along with the coronal magnetic models. Effects of active regions on the interplanetary magnetic field is discussed with particular reference to the evolution of interplanetary sectors. Interplanetary magnetic field magnitude variations are shown throughout the solar cycle. The percentage of time the field magnitude is greater than 10 gamma is shown to closely parallel sunspot number. The sun's polar field influence on the interplanetary field and alternative views of the magnetic field structure out of the ecliptic plane are presented. In addition, a variety of significantly different interplanetary field structures are discussed.
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Optical Fiber Based Thermometry System for a Hyperthermia Laboratory
2001-10-25
of the Biomedical Engineering Society. Seattle, WA. Oct 11-15, 2000. [16] O. Carranza. “Termómetro basado en fibras ópticas para aplicaciones biomédicas”. Tesis de maestría. SEPI- ESIME-IPN, México DF, Dec. 2000.
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Gelator-polysaccharide hybrid hydrogel for selective and controllable dye release.
Li, Ping; Dou, Xiao-Qiu; Tang, Yi-Tian; Zhu, Shenmin; Gu, Jiajun; Feng, Chuan-Liang; Zhang, Di
2012-12-01
In this paper, 1,4-bi(phenylalanine-diglycol)-benzene (PDB) based Low-Molecular-Weight-Gelator (LMWG) hydrogels are modified using hydrophilic polysaccharide (sodium alginate). A set of techniques including Fourier transform infrared (FT-IR) spectroscopy, (1)H Nuclear Magnetic Resonance ((1)H NMR), X-ray powder diffraction (XRD), Ultraviolet-Visible (UV-Vis), and circular dichroism (CD) had confirmed a β-turn arrangement of PDB gelators and a semi-interpenetrating network (semi-IPN), which was formed through hydrogen bonds between LMWG fibers and polysaccharide chains. The evaluation of physicochemical properties of hydrogels indicates that gelator-polysaccharide hybrid hydrogels possess better mechanical and water retention properties than LMWG hydrogels. The release study of dyes (model drug) from both LMWG and hybrid hydrogels was carried out. Compared with PDB based hydrogels, hybrid hydrogels show a selective and controllable release property for certain dyes. The results suggest LMWG-polysaccharide hybrid gels may find potential applications as promising drug delivery vehicles for drug molecules. Copyright © 2012 Elsevier Inc. All rights reserved.
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Ao, Di; Song, Rong; Tong, Kai-yu
2015-01-01
There are aging- and stroke-induced changes on sensorimotor control in daily activities, but their mechanisms have not been well investigated. This study explored speed-, aging-, and stroke-induced changes on sensorimotor control. Eleven stroke patients (affected sides and unaffected sides) and 20 control subjects (10 young and 10 age-matched individuals) were enrolled to perform elbow tracking tasks using sinusoidal trajectories, which included 6 target speeds (15.7, 31.4, 47.1, 62.8, 78.5, and 94.2 deg/s). The actual elbow angle was recorded and displayed on a screen as visual feedback, and three indicators, the root mean square error (RMSE), normalized integrated jerk (NIJ) and integral of the power spectrum density of normalized speed (IPNS), were used to investigate the strategy of sensorimotor control. Both NIJ and IPNS had significant differences among the four groups (P<0.01), and the values were ranked in the following order: young controls < age-matched controls
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Zhang, Shugang; Yang, Yuechao; Gao, Bin; Wan, Yongshan; Li, Yuncong C; Zhao, Chenhao
2016-07-20
A novel polymer-coated nitrogen (N) fertilizer was developed using bio-based polyurethane (PU) derived from liquefied locust sawdust as the coating material. The bio-based PU was successfully coated on the surface of the urea fertilizer prills to form polymer-coated urea (PCU) fertilizer for controlled N release. Epoxy resin (EP) was also used to further modify the bio-based PU to synthesize the interpenetrating network (IPN), enhancing the slow-release properties of the PCU. The N release characteristics of the EP-modified PCU (EMPCU) in water were determine at 25 °C and compared to that of PCU and EP-coated urea (ECU). The results showed that the EP modification reduced the N release rate and increased the longevity of the fertilizer coated with bio-based PU. A corn growth study was conducted to further evaluate the filed application of the EMPCU. In comparison to commercial PCU and conventional urea fertilizer, EMPCU was more effective and increased the yield and total dry matter accumulation of the corn. Findings from this work indicated that bio-based PU derived from sawdust can be used as coating materials for PCU, particularly after EP modification. The resulting EMPCU was more environmentally friendly and cost-effective than conventional urea fertilizers coated by EP.
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DOE Office of Scientific and Technical Information (OSTI.GOV)
Zhang, L.; Zhou, J.; Huang, J.
1999-11-01
Interpenetrating polymer network (IPN) coatings synthesized from castor-oil-based polyurethane (PU) with chitosan, nitrocellulose, or elaeostearin were coated on regenerated cellulose (RC) film for curing at 80--100 C for 2--5 min, providing biodegradable, water-resistant cellulose films coded, respectively, as RCCH, RCNC, and RCEs. The coated films were buried in natural soil for decaying and inoculated with a spore suspension of fungi on the agar medium, respectively, to test biodegradability. The viscosity-average molecular weight, M{sub {eta}}, and the weight of the degraded films decreased sharply with the progress of degradation. The degradation half-lifes, t{sub 1/2}, of the films in soil at 30more » C were found to be 19 days for RC, 25 days for RCNC, 32 days for RCCH, and 45 days for the RCEs films. Scanning electron microscopy (SEM) showed that the extent of decay followed in the order RC {gt} RCNC {gt} RCCH {gt} RCEs. SEM, infrared (IR), high-performance liquid chromatography (HPLC), and CO{sub 2} evolution results indicated that the microorganisms directly attacked the water-resistant coating layer and then penetrated into the cellulose to speedily metabolize, while accompanying with producing CO{sub 2}, H{sub 2}O, glucose cleaved from cellulose, and small molecules decomposed from the coatings.« less
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NASA Astrophysics Data System (ADS)
Souza, V. M. C. E. S.; Jauer, P. R.; Alves, L. R.; Padilha, A. L.; Padua, M. B.; Vitorello, I.; Alves, M. V.; Da Silva, L. A.
2017-12-01
Interplanetary structures such as Coronal Mass Ejections (CME), Shocks, Corotating Interaction Regions (CIR) and Magnetic Clouds (MC) interfere directly on Space Weather conditions and can cause severe and intense disturbances in the Earth's magnetic field as measured in space and on the ground. During magnetically disturbed periods characterized by world-wide, abrupt variations of the geomagnetic field, large and intense current systems can be induced and amplified within the Earth even at low latitudes. Such current systems are known as geomagnetically induced currents (GIC) and can cause damage to power transmission lines, transformers and the degradation of pipelines. As part of an effort to estimate GIC intensities throughout the low to equatorial latitudes of the Brazilian territory, we used the 3-D MHD SWMF/BATSRUS code to estimate spatial variations of the geomagnetic field during periods when the magnetosphere is under the influence of CME and MC structures. Specifically, we used the CalcDeltaB tool (Rastatter et al., Space Weather, 2014) to provide a proxy for the spatial variations of the geomagnetic field, with a 1 minute cadence, at 31 virtual magnetometer stations located in the proposed study region. The stations are spatially arranged in a two-dimensional network with each station being 5 degrees apart in latitude and longitude. In a preliminary analysis, we found that prior to the arrival of each interplanetary structure, there is no appreciable variation in the components of the geomagnetic field between the virtual stations. However, when the interplanetary structures reach the magnetosphere, each station perceives the magnetic field variation differently, so that it is not possible to use a single station to represent the magnetic field perturbation throughout the Brazilian region. We discuss the minimum number and spacing between stations to adequately detail the geomagnetic field variations in this region.
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Virtual Energetic Particle Observatory for the Heliospheric Data Environment
NASA Technical Reports Server (NTRS)
Cooper, J. F.; Armstrong, T. P.; Hill, M. E.; Lal, N.; McGuire, R. E.; McKibben, R. B.; Narock, T. W.; Szabo, A.; Tranquille, C.
2007-01-01
The heliosphere is pervaded by interplanetary energetic particles, traditionally also called cosmic rays, from solar, internal heliospheric, and galactic sources. The particles species of interest to heliophysics extend from plasma energies to the GeV energies of galactic cosmic rays still measurably affected by heliospheric modulation and the still higher energies contributing to atmospheric ionization. The NASA and international Heliospheric Network of operational and legacy spacecraft measures interplanetary fluxes of these particles. Spatial coverage extends from the inner heliosphere and geospace to the heliosheath boundary region now being traversed by Voyager 1 and soon by Voyager 2. Science objectives include investigation of solar flare and coronal mass ejection events, acceleration and transport of interplanetary particles within the inner heliosphere, cosmic ray interactions with planetary surfaces and atmospheres, sources of suprathermal and anomalous cosmic ray ions in the outer heliosphere, and solar cycle modulation of galactic cosmic rays. The Virtual Energetic Particle Observatory (VEPO) will improve access and usability of selected spacecraft and sub-orbital NASA heliospheric energetic particle data sets as a newly approved effort within the evolving heliophysics virtual observatory environment. In this presentation, we will describe current VEPO science requirements, our initial priorities and an overview of our strategy to implement VEPO rapidly and at minimal cost by working within the high-level framework of the Virtual Heliospheric Observatory (VHO). VEPO will also leverage existing data services of NASA's Space Physics Data Facility and other existing capabilities of the U.S. and international heliospheric research communities.
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NASA Astrophysics Data System (ADS)
Lockwood, M.; Nevanlinna, H.; Barnard, L.; Owens, M. J.; Harrison, R. G.; Rouillard, A. P.; Scott, C. J.
2014-04-01
In the concluding paper of this tetralogy, we here use the different geomagnetic activity indices to reconstruct the near-Earth interplanetary magnetic field (IMF) and solar wind flow speed, as well as the open solar flux (OSF) from 1845 to the present day. The differences in how the various indices vary with near-Earth interplanetary parameters, which are here exploited to separate the effects of the IMF and solar wind speed, are shown to be statistically significant at the 93% level or above. Reconstructions are made using four combinations of different indices, compiled using different data and different algorithms, and the results are almost identical for all parameters. The correction to the aa index required is discussed by comparison with the Ap index from a more extensive network of mid-latitude stations. Data from the Helsinki magnetometer station is used to extend the aa index back to 1845 and the results confirmed by comparison with the nearby St Petersburg observatory. The optimum variations, using all available long-term geomagnetic indices, of the near-Earth IMF and solar wind speed, and of the open solar flux, are presented; all with ±2σ uncertainties computed using the Monte Carlo technique outlined in the earlier papers. The open solar flux variation derived is shown to be very similar indeed to that obtained using the method of Lockwood et al. (1999).
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GLP-1 acts on habenular avoidance circuits to control nicotine intake.
Tuesta, Luis M; Chen, Zuxin; Duncan, Alexander; Fowler, Christie D; Ishikawa, Masago; Lee, Brian R; Liu, Xin-An; Lu, Qun; Cameron, Michael; Hayes, Matthew R; Kamenecka, Theodore M; Pletcher, Matthew; Kenny, Paul J
2017-05-01
Tobacco smokers titrate their nicotine intake to avoid its noxious effects, sensitivity to which may influence vulnerability to tobacco dependence, yet mechanisms of nicotine avoidance are poorly understood. Here we show that nicotine activates glucagon-like peptide-1 (GLP-1) neurons in the nucleus tractus solitarius (NTS). The antidiabetic drugs sitagliptin and exenatide, which inhibit GLP-1 breakdown and stimulate GLP-1 receptors, respectively, decreased nicotine intake in mice. Chemogenetic activation of GLP-1 neurons in NTS similarly decreased nicotine intake. Conversely, Glp1r knockout mice consumed greater quantities of nicotine than wild-type mice. Using optogenetic stimulation, we show that GLP-1 excites medial habenular (MHb) projections to the interpeduncular nucleus (IPN). Activation of GLP-1 receptors in the MHb-IPN circuit abolished nicotine reward and decreased nicotine intake, whereas their knockdown or pharmacological blockade increased intake. GLP-1 neurons may therefore serve as 'satiety sensors' for nicotine that stimulate habenular systems to promote nicotine avoidance before its aversive effects are encountered.
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An essential role of acetylcholine-glutamate synergy at habenular synapses in nicotine dependence
Frahm, Silke; Antolin-Fontes, Beatriz; Görlich, Andreas; Zander, Johannes-Friedrich; Ahnert-Hilger, Gudrun; Ibañez-Tallon, Ines
2015-01-01
A great deal of interest has been focused recently on the habenula and its critical role in aversion, negative-reward and drug dependence. Using a conditional mouse model of the ACh-synthesizing enzyme choline acetyltransferase (Chat), we report that local elimination of acetylcholine (ACh) in medial habenula (MHb) neurons alters glutamate corelease and presynaptic facilitation. Electron microscopy and immuno-isolation analyses revealed colocalization of ACh and glutamate vesicular transporters in synaptic vesicles (SVs) in the central IPN. Glutamate reuptake in SVs prepared from the IPN was increased by ACh, indicating vesicular synergy. Mice lacking CHAT in habenular neurons were insensitive to nicotine-conditioned reward and withdrawal. These data demonstrate that ACh controls the quantal size and release frequency of glutamate at habenular synapses, and suggest that the synergistic functions of ACh and glutamate may be generally important for modulation of cholinergic circuit function and behavior. DOI: http://dx.doi.org/10.7554/eLife.11396.001 PMID:26623516
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Odor Discrimination in Drosophila: From Neural Population Codes to Behavior
Parnas, Moshe; Lin, Andrew C.; Huetteroth, Wolf; Miesenböck, Gero
2013-01-01
Summary Taking advantage of the well-characterized olfactory system of Drosophila, we derive a simple quantitative relationship between patterns of odorant receptor activation, the resulting internal representations of odors, and odor discrimination. Second-order excitatory and inhibitory projection neurons (ePNs and iPNs) convey olfactory information to the lateral horn, a brain region implicated in innate odor-driven behaviors. We show that the distance between ePN activity patterns is the main determinant of a fly’s spontaneous discrimination behavior. Manipulations that silence subsets of ePNs have graded behavioral consequences, and effect sizes are predicted by changes in ePN distances. ePN distances predict only innate, not learned, behavior because the latter engages the mushroom body, which enables differentiated responses to even very similar odors. Inhibition from iPNs, which scales with olfactory stimulus strength, enhances innate discrimination of closely related odors, by imposing a high-pass filter on transmitter release from ePN terminals that increases the distance between odor representations. PMID:24012006
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The Goddard program of gamma ray transient astronomy
NASA Technical Reports Server (NTRS)
Cline, T. L.; Desai, U. D.; Teegarden, B. J.
1980-01-01
Gamma ray burst studies are reviewed. The past results, present status and future expectations are outlined regarding endeavors using experiments on balloons, IMP-6 and -7, OGO-3, ISEE-1 and -3, Helios-2, Solar Maximum Mission, the Einstein Observatory, Solar Polar and the Gamma Ray Observatory, and with the interplanetary gamma ray burst networks, to which some of these spacecraft sensors contribute. Additional emphasis is given to the recent discovery of a new type of gamma ray transient, detected on 1979 March 5.
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NASA Technical Reports Server (NTRS)
Fisk, L. A. (Editor); Axford, W. I. (Editor)
1976-01-01
A series of papers are presented from a symposium attended by over 200 European and American scientists to examine the importance of exploring the interplanetary medium and the sun by out-of-the-ecliptic space missions. The likely scientific returns of these missions in the areas of solar, interplanetary, and cosmic ray physics is examined. Theoretical models of the solar wind and its interaction with interplanetary magnetic fields are given.
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NASA Astrophysics Data System (ADS)
Denardini, Clezio Marcos; Padilha, Antonio; Takahashi, Hisao; Souza, Jonas; Mendes, Odim; Batista, Inez S.; SantAnna, Nilson; Gatto, Rubens; Costa, D. Joaquim
On August 2007 the National Institute for Space Research started a task force to develop and operate a space weather program, which is kwon by the acronyms Embrace that stands for the Portuguese statement “Estudo e Monitoramento BRAasileiro de Clima Espacial” Program (Brazilian Space Weather Study and Monitoring program). The main purpose of the Embrace Program is to monitor the space climate and weather from sun, interplanetary space, magnetosphere and ionosphere-atmosphere, and to provide useful information to space related communities, technological, industrial and academic areas. Since then we have being visiting several different space weather costumers and we have host two workshops of Brazilian space weather users at the Embrace facilities. From the inputs and requests collected from the users the Embrace Program decided to monitored several physical parameters of the sun-earth environment through a large ground base network of scientific sensors and under collaboration with space weather centers partners. Most of these physical parameters are daily published on the Brazilian space weather program web portal, related to the entire network sensors available. A comprehensive data bank and an interface layer are under development to allow an easy and direct access to the useful information. Nowadays, the users will count on products derived from a GNSS monitor network that covers most of the South American territory; a digisonde network that monitors the ionospheric profiles in two equatorial sites and in one low latitude site; several solar radio telescopes to monitor solar activity, and a magnetometer network, besides a global ionospheric physical model. Regarding outreach, we publish a daily bulletin in Portuguese with the status of the space weather environment on the Sun, in the Interplanetary Medium and close to the Earth. Since December 2011, all these activities are carried out at the Embrace Headquarter, a building located at the INPE's main campus. Recently, we have release brand new products, among them, some regional magnetic indices and the GNSS vertical error map over South America. Contacting Author: C. M. Denardini (clezio.denardin@inpe.br)
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Representing operations procedures using temporal dependency networks
NASA Technical Reports Server (NTRS)
Fayyad, Kristina E.; Cooper, Lynne P.
1993-01-01
DSN Link Monitor & Control (LMC) operations consist primarily of executing procedures to configure, calibrate, test, and operate a communications link between an interplanetary spacecraft and its mission control center. Currently the LMC operators are responsible for integrating procedures into an end-to-end series of steps. The research presented in this paper is investigating new ways of specifying operations procedures that incorporate the insight of operations, engineering, and science personnel to improve mission operations. The paper describes the rationale for using Temporal Dependency Networks (TDN's) to represent the procedures, a description of how the data is acquired, and the knowledge engineering effort required to represent operations procedures. Results of operational tests of this concept, as implemented in the LMC Operator Assistant Prototype (LMCOA), are also presented.
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NASA Technical Reports Server (NTRS)
Clare, Loren; Clement, B.; Gao, J.; Hutcherson, J.; Jennings, E.
2006-01-01
Described recent development of communications protocols, services, and associated tools targeted to reduce risk, reduce cost and increase efficiency of IND infrastructure and supported mission operations. Space-based networking technologies developed were: a) Provide differentiated quality of service (QoS) that will give precedence to traffic that users have selected as having the greatest importance and/or time-criticality; b) Improve the total value of information to users through the use of QoS prioritization techniques; c) Increase operational flexibility and improve command-response turnaround; d) Enable new class of networked and collaborative science missions; e) Simplify applications interfaces to communications services; and f) Reduce risk and cost from a common object model and automated scheduling and communications protocols. Technologies are described in three general areas: communications scheduling, middleware, and protocols. Additionally developed simulation environment, which provides comprehensive, quantitative understanding of the technologies performance within overall, evolving architecture, as well as ability to refine & optimize specific components.
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Deep Space Network-Wide Portal Development: Planning Service Pilot Project
NASA Technical Reports Server (NTRS)
Doneva, Silviya
2011-01-01
The Deep Space Network (DSN) is an international network of antennas that supports interplanetary spacecraft missions and radio and radar astronomy observations for the exploration of the solar system and the universe. DSN provides the vital two-way communications link that guides and controls planetary explorers, and brings back the images and new scientific information they collect. In an attempt to streamline operations and improve overall services provided by the Deep Space Network a DSN-wide portal is under development. The project is one step in a larger effort to centralize the data collected from current missions including user input parameters for spacecraft to be tracked. This information will be placed into a principal repository where all operations related to the DSN are stored. Furthermore, providing statistical characterization of data volumes will help identify technically feasible tracking opportunities and more precise mission planning by providing upfront scheduling proposals. Business intelligence tools are to be incorporated in the output to deliver data visualization.
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NASA Astrophysics Data System (ADS)
Grigoryev, V. G.; Starodubtsev, S. A.; Potapova, V. D.
2013-02-01
In our previous works we have created the method of determination of parameters of cosmic ray daily anisotropy in the interplanetary environment based on the data provided by only single station - cosmic ray spectrograph named after A.I.Kuzmin. This method allows to predict the ingress of the Earth into large-scale solar wind disturbances with a probability of more than 70% and in advance time of about from several hours up to 2 days. Now it became possible to use the data of the neutron monitor networks, which can be seen in the neutron monitor database (NMDB) in real time. In this case the well-known method of global survey is applied for determination of cosmic ray anisotropy. Usage of the data of the cosmic ray station network allows to determine parameters of daily cosmic ray anisotropy with a greater accuracy.
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Interplanetary Program to Optimize Simulated Trajectories (IPOST). Volume 3: Programmer's manual
NASA Technical Reports Server (NTRS)
Hong, P. E.; Kent, P. D.; Olson, D. W.; Vallado, C. A.
1992-01-01
The Interplanetary Program to Optimize Space Trajectories (IPOST) is intended to support many analysis phases, from early interplanetary feasibility studies through spacecraft development and operations. Here, information is given on the IPOST code.
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A history of the deep space network
NASA Technical Reports Server (NTRS)
Corliss, W. R.
1976-01-01
The Deep Space Network (DSN) has been managed and operated by the Jet Propulsion Laboratory (JPL) under NASA contract ever since NASA was formed in late 1958. The Tracking and data acquisition tasks of the DSN are markedly different from those of the other NASA network, STDN. STDN, which is an amalgamation of the satellite tracking network (STADAN) and the Manned Space Flight Network (MSFN), is primarily concerned with supporting manned and unmanned earth satellites. In contrast, the DSN deals with spacecraft that are thousands to hundreds of millions of miles away. The radio signals from these distant craft are many orders of magnitude weaker than those from nearby satellites. Distance also makes precise radio location more difficult; and accurate trajectory data are vital to deep space navigation in the vicinities of the other planets of the solar system. In addition to tracking spacecraft and acquiring data from them, the DSN is required to transmit many thousands of commands to control the sophisticated planetary probes and interplanetary monitoring stations. To meet these demanding requirements, the DSN has been compelled to be in the forefront of technology.
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Contact Graph Routing Enhancements Developed in ION for DTN
NASA Technical Reports Server (NTRS)
Segui, John S.; Burleigh, Scott
2013-01-01
The Interplanetary Overlay Network (ION) software suite is an open-source, flight-ready implementation of networking protocols including the Delay/Disruption Tolerant Networking (DTN) Bundle Protocol (BP), the CCSDS (Consultative Committee for Space Data Systems) File Delivery Protocol (CFDP), and many others including the Contact Graph Routing (CGR) DTN routing system. While DTN offers the capability to tolerate disruption and long signal propagation delays in transmission, without an appropriate routing protocol, no data can be delivered. CGR was built for space exploration networks with scheduled communication opportunities (typically based on trajectories and orbits), represented as a contact graph. Since CGR uses knowledge of future connectivity, the contact graph can grow rather large, and so efficient processing is desired. These enhancements allow CGR to scale to predicted NASA space network complexities and beyond. This software improves upon CGR by adopting an earliest-arrival-time cost metric and using the Dijkstra path selection algorithm. Moving to Dijkstra path selection also enables construction of an earliest- arrival-time tree for multicast routing. The enhancements have been rolled into ION 3.0 available on sourceforge.net.
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Network Monitor and Control of Disruption-Tolerant Networks
NASA Technical Reports Server (NTRS)
Torgerson, J. Leigh
2014-01-01
For nearly a decade, NASA and many researchers in the international community have been developing Internet-like protocols that allow for automated network operations in networks where the individual links between nodes are only sporadically connected. A family of Disruption-Tolerant Networking (DTN) protocols has been developed, and many are reaching CCSDS Blue Book status. A NASA version of DTN known as the Interplanetary Overlay Network (ION) has been flight-tested on the EPOXI spacecraft and ION is currently being tested on the International Space Station. Experience has shown that in order for a DTN service-provider to set up a large scale multi-node network, a number of network monitor and control technologies need to be fielded as well as the basic DTN protocols. The NASA DTN program is developing a standardized means of querying a DTN node to ascertain its operational status, known as the DTN Management Protocol (DTNMP), and the program has developed some prototypes of DTNMP software. While DTNMP is a necessary component, it is not sufficient to accomplish Network Monitor and Control of a DTN network. JPL is developing a suite of tools that provide for network visualization, performance monitoring and ION node control software. This suite of network monitor and control tools complements the GSFC and APL-developed DTN MP software, and the combined package can form the basis for flight operations using DTN.
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NASA Technical Reports Server (NTRS)
Dryer, M. (Editor); Tandberg-Hanssen, E.
1980-01-01
The symposium focuses on solar phenomena as the source of transient events propagating through the solar system, and theoretical and observational assessments of the dynamic processes involved in these events. The topics discussed include the life history of coronal structures and fields, coronal and interplanetary responses to long time scale phenomena, solar transient phenomena affecting the corona and interplanetary medium, coronal and interplanetary responses to short time scale phenomena, and future directions.
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The "Approximate 150 Day Quasi-Periodicity" in Interplanetary and Solar Phenomena During Cycle 23
NASA Technical Reports Server (NTRS)
Richardson, I. G.; Cane, H. V.
2004-01-01
A"quasi-periodicity" of approx. 150 days in various solar and interplanetary phenomena has been reported in earlier solar cycles. We suggest that variations in the occurrence of solar energetic particle events, inter-planetary coronal mass ejections, and geomagnetic storm sudden commenceents during solar cycle 23 show evidence of this quasi-periodicity, which is also present in the sunspot number, in particular in the northern solar hemisphere. It is not, however, prominent in the interplanetary magnetic field strength.
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Genesis of Interplanetary Intermittent Turbulence: a Case Study of Rope-Rope Magnetic Reconnection
NASA Technical Reports Server (NTRS)
Chian, Abraham C.- L.; Feng, Heng Q.; Hu, Qiang; Loew, Murray H.; Miranda, Rodrigo A.; Munoz, Pablo R.; Sibeck, David G.; Wu, De J.
2016-01-01
In a recent paper, the relation between current sheet, magnetic reconnection, and turbulence at the leading edge of an interplanetary coronal mass ejection was studied. We report here the observation of magnetic reconnection at the interface region of two interplanetary magnetic flux ropes. The front and rear boundary layers of three interplanetary magnetic flux ropes are identified, and the structures of magnetic flux ropes are reconstructed by the Grad Shafranov method. A quantitative analysis of the reconnection condition and the degree of intermittency reveals that rope-rope magnetic reconnection is the most likely site for genesis of interplanetary intermittency turbulence in this event. The dynamic pressure pulse resulting from this reconnection triggers the onset of a geomagnetic storm.
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FRIPON, the French fireball network
NASA Astrophysics Data System (ADS)
Colas, F.; Zanda, B.; Bouley, S.; Vaubaillon, J.; Marmo, C.; Audureau, Y.; Kwon, M. K.; Rault, J. L.; Caminade, S.; Vernazza, P.; Gattacceca, J.; Birlan, M.; Maquet, L.; Egal, A.; Rotaru, M.; Gruson-Daniel, Y.; Birnbaum, C.; Cochard, F.; Thizy, O.
2015-10-01
FRIPON (Fireball Recovery and InterPlanetary Observation Network) [4](Colas et al, 2014) was recently founded by ANR (Agence Nationale de la Recherche). Its aim is to connect meteoritical science with asteroidal and cometary science in order to better understand solar system formation and evolution. The main idea is to set up an observation network covering all the French territory to collect a large number of meteorites (one or two per year) with accurate orbits, allowing us to pinpoint possible parent bodies. 100 all-sky cameras will be installed at the end of 2015 forming a dense network with an average distance of 100km between stations. To maximize the accuracy of orbit determination, we will mix our optical data with radar data from the GRAVES beacon received by 25 stations [5](Rault et al, 2015). As both the setting up of the network and the creation of search teams for meteorites will need manpower beyond our small team of professionals, we are developing a citizen science network called Vigie-Ciel [6](Zanda et al, 2015). The public at large will thus be able to simply use our data, participate in search campaigns or even setup their own cameras.
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Scattering Banner Acknowledgements The graphics used on the Neutron Scattering Web Pages were designed by reused on these web pages by kind permission of Jack Carpenter, and with the assistance of Mary Koelbl (IPD). Rick Goyette (IPNS) set up and maintains the Linux web server as well as helping to automate the
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CREADS, a Teacher Training Course on ESD in Costa Rica
ERIC Educational Resources Information Center
Jimenez-Elizondo, Alicia
2010-01-01
After the Costa Rican government signed a commitment to implement the UN Decade of Education for Sustainable Development (DESD), the challenge was how to put the commitment into action. Fortunately, an opportunity presented itself with an initiative called Peace with Nature (Iniciativa Paz con la Naturaleza-IPN), under which a teacher training…
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METABOLISM OF VINCLOZOLIN AND ITS METABOLITES IN RATS
ETD-04-008
METABOLISM OF VINCLOZOLIN AND ITS METABOLITES IN RAT. A Sierra-Santoyo1, R Harrison2, H A Barton2 and M F Hughes2. 1Toxicology Section, CINVESTAV-IPN, Mexico City, Mexico; 2USEPA, ORD, NHEERL, RTP, NC.
Vinclozolin (V) is a fungicide used in agricultural... -
HPLC ANALYSIS OF VINCLOZOLIN AND ITS METABOLITES IN SERUM
HPLC ANALYSIS OF VINCLOZOLIN AND ITS METABOLITES IN SERUM. A Sierra-Santoyo1,2, H A Barton1 and M F Hughes1. 1US EPA, ORD, NHEERL, ETD, RTP, NC; 2Toxicology Section, CINVESTAV-IPN, Mexico City, Mexico.
The fungicide vinclozolin (V) is used predominantly for treatment... -
Behavior of ionic conducting IPN actuators in simulated space conditions
NASA Astrophysics Data System (ADS)
Fannir, Adelyne; Plesse, Cédric; Nguyen, Giao T. M.; Laurent, Elisabeth; Cadiergues, Laurent; Vidal, Frédéric
2016-04-01
The presentation focuses on the performances of flexible all-polymer electroactive actuators under space-hazardous environmental factors in laboratory conditions. These bending actuators are based on high molecular weight nitrile butadiene rubber (NBR), poly(ethylene oxide) (PEO) derivative and poly(3,4-ethylenedioxithiophene) (PEDOT). The electroactive PEDOT is embedded within the PEO/NBR membrane which is subsequently swollen with an ionic liquid as electrolyte. Actuators have been submitted to thermal cycling test between -25 to 60°C under vacuum (2.4 10-8 mbar) and to ionizing Gamma radiations at a level of 210 rad/h during 100 h. Actuators have been characterized before and after space environmental condition ageing. In particular, the viscoelasticity properties and mechanical resistance of the materials have been determined by dynamic mechanical analysis and tensile tests. The evolution of the actuation properties as the strain and the output force have been characterized as well. The long-term vacuuming, the freezing temperature and the Gamma radiations do not affect significantly the thermomechanical properties of conducting IPNs actuators. Only a slight decrease on actuation performances has been observed.
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Huang, Zhicheng; Gu, Yu; Liu, Xiaodong; Zhang, Lifen; Cheng, Zhenping; Zhu, Xiulin
2017-05-01
It is well known that the recently developed photoinduced metal-free atom transfer radical polymerization (ATRP) has been considered as a promising methodology to completely eliminate transition metal residue in polymers. However, a serious problem needs to be improved, namely, large amount of organic photocatalysts should be used to keep the controllability over molecular weights and molecular weight distributions. In this work, a novel photocatalyst 1,2,3,5-tetrakis(carbazol-9-yl)-4,6-dicyanobenzene (4CzIPN) with strong excited state reduction potential is successfully used to mediate a metal-free ATRP of methyl methacrylate just with parts per million (ppm) level usage under irradiation of blue light emitting diode at room temperature, using ethyl α-bromophenyl-acetate as a typical initiator with high initiator efficiency. The polymerization kinetic study, multiple controlled "on-off" light switching cycle regulation, and chain extension experiment confirm the "living"/controlled features of this promising photoinduced metal-free ATRP system with good molecular weight control in the presence of ppm level photocatalyst 4CzIPN. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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Odor discrimination in Drosophila: from neural population codes to behavior.
Parnas, Moshe; Lin, Andrew C; Huetteroth, Wolf; Miesenböck, Gero
2013-09-04
Taking advantage of the well-characterized olfactory system of Drosophila, we derive a simple quantitative relationship between patterns of odorant receptor activation, the resulting internal representations of odors, and odor discrimination. Second-order excitatory and inhibitory projection neurons (ePNs and iPNs) convey olfactory information to the lateral horn, a brain region implicated in innate odor-driven behaviors. We show that the distance between ePN activity patterns is the main determinant of a fly's spontaneous discrimination behavior. Manipulations that silence subsets of ePNs have graded behavioral consequences, and effect sizes are predicted by changes in ePN distances. ePN distances predict only innate, not learned, behavior because the latter engages the mushroom body, which enables differentiated responses to even very similar odors. Inhibition from iPNs, which scales with olfactory stimulus strength, enhances innate discrimination of closely related odors, by imposing a high-pass filter on transmitter release from ePN terminals that increases the distance between odor representations. Copyright © 2013 The Authors. Published by Elsevier Inc. All rights reserved.
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Jacewicz, Renata; Ossowski, Andrzej; Ławrynowicz, Olgierd; Jędrzejczyk, Maciej; Prośniak, Adam; Bąbol-Pokora, Katarzyna; Diepenbroek, Marta; Szargut, Maria; Zielińska, Grażyna; Berent, Jarosław
2017-01-01
It can be reasonably assumed that remains exhumed in 2012 and 2013 during archaeological explorations conducted in the Lućmierz Forest, an important area on the map of the German Nazi terror in the region of Lodz (Poland), are in fact the remains of a hundred Poles murdered by the Nazis in Zgierz on March 20, 1942. By virtue of a decision of the Polish Institute of National Remembrance's Commission for the Prosecution of Crimes Against the Polish Nation, the verification of this research hypothesis was entrusted to SIGO (Network for Genetic Identification of Victims) Consortium appointed by virtue of an agreement of December 11, 2015. The Consortium is an extension of the PBGOT (Polish Genetic Database of Totalitarianisms Victims). So far, the researchers have retrieved 14 DNA profiles from among the examined remains, including 12 male and 2 female profiles. Furthermore, 12 DNA profiles of the victims' family members have been collected. Due to the fact that next-of-kin relatives of the victims of the Zgierz massacre are of advanced age, it is of key importance to collect genetic material as soon as possible from the other surviving family members, identified on the basis of a list of victims that has been nearly completely compiled by the Polish Institute of National Remembrance (IPN) and is presented in this paper.
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GENESIS OF INTERPLANETARY INTERMITTENT TURBULENCE: A CASE STUDY OF ROPE–ROPE MAGNETIC RECONNECTION
DOE Office of Scientific and Technical Information (OSTI.GOV)
Chian, Abraham C.-L.; Loew, Murray H.; Feng, Heng Q.
In a recent paper, the relation between current sheet, magnetic reconnection, and turbulence at the leading edge of an interplanetary coronal mass ejection was studied. We report here the observation of magnetic reconnection at the interface region of two interplanetary magnetic flux ropes. The front and rear boundary layers of three interplanetary magnetic flux ropes are identified, and the structures of magnetic flux ropes are reconstructed by the Grad–Shafranov method. A quantitative analysis of the reconnection condition and the degree of intermittency reveals that rope–rope magnetic reconnection is the most likely site for genesis of interplanetary intermittency turbulence in this event.more » The dynamic pressure pulse resulting from this reconnection triggers the onset of a geomagnetic storm.« less
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NASA Astrophysics Data System (ADS)
Armstrong, T. P.; Manweiler, J. W.; Gerrard, A. J.; Gkioulidou, M.; Lanzerotti, L. J.; Patterson, J. D.
2013-12-01
Observations from ACE EPAM including energy spectra of protons, helium, and oxygen will be prepared for coordinated use in estimating the direct and indirect access of energetic particles to inner and outer geomagnetic trapping zones. Complete temporal coverage from ACE at 12 seconds, 5 minutes, 17 minutes, hourly and daily cadences will be used to catalog interplanetary events arriving at Earth including interplanetary magnetic field sector boundaries, interplanetary shocks, and interplanetary coronal mass ejections, ICMEs. The first 6 months of 2013 have included both highly disturbed times, March 17 and May 22, and extended quiet periods of little or no variations. Among the specific questions that ACE and Van Allen Probes coordinated observations may aid in resolving are: 1. How much, if any, direct capture of interplanetary energetic particles occurs and what conditions account for it? 2. How much influence do interplanetary field and particle variations have on energization and/or loss of geomagnetically trapped populations? The poster will also present important links and describe methods and important details of access to numerically expressed ACE EPAM and Van Allen Probes RBSPICE observations that can be flexibly and easily accessed via the internet for student and senior researcher use.
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The effect of a novel minimally invasive strategy for infected necrotizing pancreatitis.
Tong, Zhihui; Shen, Xiao; Ke, Lu; Li, Gang; Zhou, Jing; Pan, Yiyuan; Li, Baiqiang; Yang, Dongliang; Li, Weiqin; Li, Jieshou
2017-11-01
Step-up approach consisting of multiple minimally invasive techniques has gradually become the mainstream for managing infected pancreatic necrosis (IPN). In the present study, we aimed to compare the safety and efficacy of a novel four-step approach and the conventional approach in managing IPN. According to the treatment strategy, consecutive patients fulfilling the inclusion criteria were put into two time intervals to conduct a before-and-after comparison: the conventional group (2010-2011) and the novel four-step group (2012-2013). The conventional group was essentially open necrosectomy for any patient who failed percutaneous drainage of infected necrosis. And the novel drainage approach consisted of four different steps including percutaneous drainage, negative pressure irrigation, endoscopic necrosectomy and open necrosectomy in sequence. The primary endpoint was major complications (new-onset organ failure, sepsis or local complications, etc.). Secondary endpoints included mortality during hospitalization, need of emergency surgery, duration of organ failure and sepsis, etc. Of the 229 recruited patients, 92 were treated with the conventional approach and the remaining 137 were managed with the novel four-step approach. New-onset major complications occurred in 72 patients (78.3%) in the two-step group and 75 patients (54.7%) in the four-step group (p < 0.001). For other important endpoints, although there was no statistical difference in mortality between the two groups (p = 0.403), significantly fewer patients in the four-step group required emergency surgery when compared with the conventional group [14.6% (20/137) vs. 45.6% (42/92), p < 0.001]. In addition, stratified analysis revealed that the four-step approach group presented significantly lower incidence of new-onset organ failure and other major complications in patients with the most severe type of AP. Comparing with the conventional approach, the novel four-step approach significantly reduced the rate of new-onset major complications and requirement of emergency operations in treating IPN, especially in those with the most severe type of acute pancreatitis.
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Field validation of experimental challenge models for IPN vaccines.
Ramstad, A; Romstad, A B; Knappskog, D H; Midtlyng, P J
2007-12-01
Atlantic salmon S1/2 pre-smolts from the VESO Vikan hatchery were assigned to study groups, i.p. immunized with commercially available, multivalent oil-adjuvanted vaccines with (Norvax Compact 6 - NC-6) or without (Norvax Compact 4 - NC-4) recombinant infectious pancreatic necrosis virus (IPNV) antigen. A control group received saline solution. When ready for sea, the fish were transported to the VESO Vikan experimental laboratory, where two identical tanks were stocked with 75 fish per group before being transferred to 10 degrees C sea water and exposed by bath to first passage IPNV grown in CHSE-214 cells. The third tank containing 40 fish from each group was challenged by the introduction of 116 fish that had received an i.p injection of IPNV-challenge material. The remaining vaccinated fish were transported to the VESO Vikan marine field trial site and placed in two identical pens, each containing approximately 53 000 fish from the NC-6 group and 9000 fish from the NC-4 group. In the experimental bath challenge trial, the cumulative mortality was 75% and 78% in the control groups, and the relative percentage survival (RPS) of the NC-6-immunized fish vs. the reference vaccine groups was 60% and 82%, respectively. In the cohabitation challenge, the control mortality reached 74% and the IPNV-specific vaccine RPS was 72%. In both models, the reference vaccine lacking IPNV antigen gave a moderate but statistically significant non-specific protection. In the field, a natural outbreak of infectious pancreatic necrosis (IPN) occurred after 7 weeks lasting for approximately 3.5 months before problems due to winter ulcers became dominating. During this outbreak, mortality in the NC-4 groups were 33.5% and 31.6%, respectively, whereas mortality in the NC-6 groups were 6.9% and 5.3%, respectively, amounting to 81% IPNV-specific protection. In conclusion, the IPN protection estimates obtained by experimental challenges were consistent between tanks, and were confirmed by the field results.
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DOE Office of Scientific and Technical Information (OSTI.GOV)
Jakes, Joseph E.; Hunt, Chris G.; Yelle, Daniel J.
Understanding and controlling molecular-scale interactions between adhesives and wood polymers are critical to accelerate the development of improved adhesives for advanced wood-based materials. The submicrometer resolution of synchrotron-based X-ray fluorescence microscopy (XFM) was found capable of mapping and quantifying infiltration of Br-labeled phenolformaldehyde (BrPF) into wood cell walls. Cell wall infiltration of five BrPF adhesives with different average molecular weights (MWs) was mapped. Nanoindentation on the same cell walls was performed to assess the effects of BrPF infiltration on cell wall hygromechanical properties. For the same amount of weight uptake, lower MW BrPF adhesives were found to be more effectivemore » at decreasing moisture-induced mechanical softening. This greater effectiveness of lower MW phenolic adhesives likely resulted from their ability to more intimately associate with water sorption sites in the wood polymers. Evidence also suggests that a BrPF interpenetrating polymer network (IPN) formed within the wood polymers, which might also decrease moisture sorption by mechanically restraining wood polymers during swelling.« less
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Song, Se Yeon; Park, Min Soo; Lee, Jung Woo; Yun, Ji Sun
2018-02-07
Silane coupling agents (SCAs) with different organofunctional groups were coated on the surfaces of Al₂O₃ ceramic particles through hydrolysis and condensation reactions, and the SCA-coated Al₂O₃ ceramic particles were dispersed in a commercial photopolymer based on interpenetrating networks (IPNs). The organofunctional groups that have high radical reactivity and are more effective in UV curing systems are usually functional groups based on acryl, such as acryloxy groups, methacrloxy groups, and acrylamide groups, and these silane coupling agents seem to improve interfacial adhesion and dispersion stability. The coating morphology and the coating thickness distribution of SCA-coated Al₂O₃ ceramic particles according to the different organofunctional groups were observed by FE-TEM. The initial dispersibility and dispersion stability of the SCA-coated Al₂O₃/High-temp composite solutions were investigated by relaxation NMR and Turbiscan. The rheological properties of the composite solutions were investigated by viscoelastic analysis and the mechanical properties of 3D-printed objects were observed with a nanoindenter.
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Song, Se Yeon; Park, Min Soo; Lee, Jung Woo; Yun, Ji Sun
2018-01-01
Silane coupling agents (SCAs) with different organofunctional groups were coated on the surfaces of Al2O3 ceramic particles through hydrolysis and condensation reactions, and the SCA-coated Al2O3 ceramic particles were dispersed in a commercial photopolymer based on interpenetrating networks (IPNs). The organofunctional groups that have high radical reactivity and are more effective in UV curing systems are usually functional groups based on acryl, such as acryloxy groups, methacrloxy groups, and acrylamide groups, and these silane coupling agents seem to improve interfacial adhesion and dispersion stability. The coating morphology and the coating thickness distribution of SCA-coated Al2O3 ceramic particles according to the different organofunctional groups were observed by FE-TEM. The initial dispersibility and dispersion stability of the SCA-coated Al2O3/High-temp composite solutions were investigated by relaxation NMR and Turbiscan. The rheological properties of the composite solutions were investigated by viscoelastic analysis and the mechanical properties of 3D-printed objects were observed with a nanoindenter. PMID:29414912
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Correlation of interplanetary-space B sub z field fluctuations and trapped-particle redistribution.
NASA Technical Reports Server (NTRS)
Parks, G. K.; Pellat, R.
1972-01-01
Observations of interplanetary magnetic field fluctuations in correlation with trapped particle fluctuations are discussed. From observations of particle-redistribution effects, properties of the magnetospheric electric field are derived. The obtained results suggest that the interplanetary B(sub z) field fluctuations might represent a strong driving source for particle diffusion.
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Radio-scintillation observations of interplanetary disturbances
DOE Office of Scientific and Technical Information (OSTI.GOV)
Watanabe, T.; Kakinuma, T.
1984-01-01
Recent developments in the studies of interplanetary disturbances by scintillation techniques are briefly reviewed. The turbulent postshock region of an interplanetary disturbance produces transient enhancements in the scintillation level and the flow speed in many cases. An empirical method to determine three-dimensional angular distribution of the propagation speed of the disturbance on the basis of interplanetary scintillation measurements of postshock flow speeds is applied to 17 events which took place in 1978-1981. Among them, four representative examples, including two events which were associated with disappearing solar filaments, are described in detail. Several disturbances had oblate configurations the latitudinal extent ismore » smaller than the longitudinal extent. On the average, the angular distribution of the propagation speed at 1-AU heliocentric distance is quasi-isotropic over a longitudinal range of 100 deg centered at the normal of relevant solar phenomenon. The net excess mass and energy in an interplanetary disturbance associated with a disappearing solar filament can be comparable to those of an interplanetary disturbance associated with a large solar flare. 57 references.« less
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NASA Technical Reports Server (NTRS)
Figueroa-Vinas, Adolfo; Nieves-Chinchilla, Teresa; Vourlidas, Angelos; Gomez-Herrero, Raul; Malandraki, Olga; Szabo, Adam; Dresing, Nina; Davila, Joseph M.
2010-01-01
EUV disk imagers and white light coronagraphs have provided for many years information on the early formation and evolution of corona) mass ejections (CMEs). More recently, the novel heliospheric imaging instruments aboard the STEREO mission are providing crucial remote sensing information on the interplanetary evolution of these events while in situ instruments complete the overall characterization of the interplanetary CMEs. In this work, we present an analysis of CMEs from the Sun to the interplanetary medium using combined data from THE SOHO, STEREO, WIND, and ACE spacecraft. The events were selected to cover the widest possible spectrum of different ambient solar wind, magnetic field configurations, plasma parameters, etc. to allow uncovering those aspects that are important in understanding the propagation and evolution mechanisms of CMEs in the interplanetary medium.
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Interplanetary Coronal Mass Ejections During 1996 - 2007
NASA Technical Reports Server (NTRS)
Richardson, I. G.; Cane, H. V.
2007-01-01
Interplanetary coronal mass ejections, the interplanetary counterparts of coronal mass ejections at the Sun, are the major drivers of interplanetary shocks in the heliosphere, and are associated with modulations of the galactic cosmic ray intensity, both short term (Forbush decreases caused by the passage of the shock, post-shock sheath, and ICME), and possibly with longer term modulation. Using several in-situ signatures of ICMEs, including plasma temperature, and composition, magnetic fields, and cosmic ray modulations, made by near-Earth spacecraft, we have compiled a "comprehensive" list of ICMEs passing the Earth since 1996, encompassing solar cycle 23. We summarize the properties of these ICMEs, such as their occurrence rate, speeds and other parameters, the fraction of ICMEs that are classic magnetic clouds, and their association with solar energetic particle events, halo CMEs, interplanetary shocks, geomagnetic storms, shocks and cosmic ray decreases.
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Study of large Forbush decreases in cosmic-ray intensity observed during solar cycle 23 and 24
NASA Astrophysics Data System (ADS)
Kumar, Anand; Badruddin, B.
2016-07-01
Neutron monitors at different geomagnetic latitude and longitude of Earth measure the cosmic-ray intensity with high precision. Sudden decreases in cosmic-ray intensity within few hours and slow recovery to pre-decrease level within a few days (Forbush decreases) are observed in neutron monitor data. We identify large-amplitude Forbush decreases (FDs), using high counting rate neutron monitor data, that occurred during previous solar cycle 23 (1995-2009) and current solar cycle 24 (2010-2015). We then search for the solar sources and the interplanetary structures responsible for these decreases. We attempt to find the relative importance of various interplanetary plasma and field parameters and the physical mechanism(s) responsible for FDs of varying amplitudes. We analyze a number of interplanetary plasma and field parameters, during both the phases (main and recovery) of FDs. The interplanetary plasma and field data analyzed in this study are the solar-wind velocity, the interplanetary magnetic field, its fluctuations, interplanetary electric field and the time variation of interplanetary electric potential. For monitoring the changes in interplanetary plasma/field conditions during the development of FDs, we also utilize plasma density, temperature and plasma beta, dynamic pressure and Mach number during the passage of interplanetary structures responsible for FDs. In addition to their amplitude, we study the recovery of FDs in detail after determining the time constant during their recovery by exponential fit to the data. As the solar magnetic polarity reversed during the maximum phase of solar cycle 23 (in the year 2000), we study the differences in amplitude, time constant of recovery and plasma/field condition to search for the polarity dependent effects, if any, on the amplitude and recovery of FDs due to implication for the models suggested to explain the Forbush decrease phenomena. The implications of these results are discussed.
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ESOC's System for Interplanetary Orbit Determination: Implementation and Operational Experience
NASA Astrophysics Data System (ADS)
Budnik, F.; Morley, T. A.; MacKenzie, R. A.
A system for interplanetary orbit determination has been developed at ESOC over the past six years. Today, the system is in place and has been proven to be both reliable and robust by successfully supporting critical operations of ESA's interplanetary spacecraft Rosetta, Mars Express, and SMART-1. To reach this stage a long and challenging way had to be travelled. This paper gives a digest about the journey from the development and testing to the operational use of ESOC's new interplanetary orbit determination system. It presents the capabilities and reflects experiences gained from the performed tests and tracking campaigns.
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DETERMINATION OF URINARY TRIVALENT ARSENICALS (MMAsIII and DMAsIII) IN INDIVIDUALS CHRONICALLY EXPOSED TO ARSENIC.
L. M. Del Razo1, M. Styblo2, W. R. Cullen3, and D.J. Thomas4.
1Toxicology Section, Cinvestav-IPN, Mexico, D.F., 2Univ. North Carolina, Chapel Hill, NC; 3Uni... -
NASA Astrophysics Data System (ADS)
Bisi, M. M.; Fallows, R. A.; Jackson, B. V.; Tokumaru, M.; Gonzalez-Esparza, A.; Morgan, J.; Chashei, I. V.; Mejia-Ambriz, J.; Tyul'bashev, S. A.; Manoharan, P. K.; De la Luz, V.; Aguilar-Rodriguez, E.; Yu, H. S.; Barnes, D.; Chang, O.; Odstrcil, D.; Fujiki, K.; Shishov, V.
2017-12-01
Interplanetary Scintillation (IPS) allows for the determination of velocity and a proxy for plasma density to be made throughout the corona and inner heliosphere. Where sufficient observations are undertaken, the results can be used as input to the University of California, San Diego (UCSD) three-dimensional (3-D) time-dependent tomography suite to allow for the full 3-D reconstruction of both velocity and density throughout the inner heliosphere. By combining IPS results from multiple observing locations around the planet, we can increase both the temporal and spatial coverage across the whole of the inner heliosphere and hence improve forecast capability. During October 2016, a unique opportunity arose whereby the European-based LOw Frequency ARray (LOFAR) radio telescope was used to make nearly four weeks of continuous observations of IPS as a heliospheric space-weather trial campaign. This was expanded into a global effort to include observations of IPS from the Murchison Widefield Array (MWA) in Western Australia and many more observations from various IPS-dedicated WIPSS Network systems. LOFAR is a next-generation low-frequency radio interferometer capable of observing in the radio frequency range 10-250 MHz, nominally with up to 80 MHz bandwidth at a time. MWA in Western Australia is capable of observing in the 80-300 MHz frequency range nominally using up to 32 MHz of bandwidth. IPS data from LOFAR, ISEE, the MEXican Array Radio Telescope (MEXART), and, where possible, other WIPSS Network systems (such as LPI-BSA and Ooty), will be used in this study and we will present some initial findings for these data sets. We also make a first attempt at the 3-D reconstruction of multiple pertinent WIPSS results in the UCSD tomography. We will also try to highlight some of the potential future tools that make LOFAR a very unique system to be able to test and validate a whole plethora of IPS analysis methods with the same set of IPS data.
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Global Magnetospheric Response to an Interplanetary Shock: THEMIS Observations
NASA Technical Reports Server (NTRS)
Zhang, Hui; Sibeck, David G.; Zong, Q.-G.; McFadden, James P.; Larson, Davin; Glassmeier, K.-H.; Angelopoulos, V.
2011-01-01
We investigate the global response of geospace plasma environment to an interplanetary shock at approx. 0224 UT on May 28, 2008 from multiple THEMIS spacecraft observations in the magnetosheath (THEMIS B and C) and the mid-afternoon (THEMIS A) and dusk magnetosphere (THEMIS D and E). The interaction of the transmitted interplanetary shock with the magnetosphere has global effects. Consequently, it can affect geospace plasma significantly. After interacting with the bow shock, the interplanetary shock transmitted a fast shock and a discontinuity which propagated through the magnetosheath toward the Earth at speeds of 300 km/s and 137 km/s respectively. THEMIS A observations indicate that the plasmaspheric plume changed significantly by the interplanetary shock impact. The plasmaspheric plume density increased rapidly from 10 to 100/ cubic cm in 4 min and the ion distribution changed from isotropic to strongly anisotropic distribution. Electromagnetic ion cyclotron (EMIC) waves observed by THEMIS A are most likely excited by the anisotropic ion distributions caused by the interplanetary shock impact. To our best knowledge, this is the first direct observation of the plasmaspheric plume response to an interplanetary shock's impact. THEMIS A, but not D or E, observed a plasmaspheric plume in the dayside magnetosphere. Multiple spacecraft observations indicate that the dawn-side edge of the plasmaspheric plume was located between THEMIS A and D (or E).
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High energy astronomy or astrophysics and properties of the interplanetary plasma
NASA Technical Reports Server (NTRS)
1971-01-01
The research activities related to high energy astrophysics and interplanetary plasma are reported. The experimental work in the following areas are described: (1) balloon-and rocket-borne cosmic X-ray, (2) X-ray spectroscopy, and (3) OSO-3 gamma ray experiment. Plasma studies in the interplanetary region, magnetosphere, and geomagnetic tail are included.
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The Polar Ionosphere and Interplanetary Field.
1987-08-01
model for investigating time dependent behavior of the Polar F-region ionosphere in response to varying interplanetary magnetic field (IMF...conditions. The model has been used to illustrate ionospheric behavior during geomagnetic storms conditions. Future model applications may include...magnetosphere model for investigating time dependent behavior of the polar F-region ionosphere in response to varying interplanetary magnetic field
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NASA Astrophysics Data System (ADS)
Dougherty, K.; Sarkissian, J.
2002-01-01
The recent Australian film, The Dish, highlighted the role played by the Parkes Radio Telescope in tracking and communicating with the Apollo 11 mission. However the events depicted in this film represent only a single snapshot of the role played by Australian radio astronomy and space tracking facilities in the exploration of the Solar System. In 1960, NASA established its first deep space tracking station outside the United States at Island Lagoon, near Woomera in South Australia. From 1961 until 1972, this station was an integral part of the Deep Space Network, responsible for tracking and communicating with NASA's interplanetary spacecraft. It was joined in 1965 by the Tidbinbilla tracking station, located near Canberra in eastern Australia, a major DSN facility that is still in operation today. Other NASA tracking facilities (for the STADAN and Manned Space Flight networks) were also established in Australia during the 1960s, making this country home to the largest number of NASA tracking facilities outside the United States. At the same time as the Island Lagoon station was being established in South Australia, one of the world's major radio telescope facilities was being established at Parkes, in western New South Wales. This 64-metre diameter dish, designed and operated by the Commonwealth Scientific and Industrial Research Organisation (CSIRO), was also well-suited for deep space tracking work: its design was, in fact, adapted by NASA for the 64-metre dishes of the Deep Space Network. From Mariner II in 1962 until today, the Parkes Radio Telescope has been contracted by NASA on many occasions to support interplanetary spacecraft, as well as the Apollo lunar missions. This paper will outline the role played by both the Parkes Radio Telescope and the NASA facilities based in Australia in the exploration of the Solar System between 1960 and 1976, when the Viking missions landed on Mars. It will outline the establishment and operation of the Deep Space Network in Australia and consider the joint US-Australian agreement under which it was managed. It will also discuss the relationship of the NASA stations to the Parkes Radio Telescope and the integration of Parkes into the NASA network to support specific space missions. The particular involvement of Australian facilities in significant space missions will be highlighted and assessed.
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Semi-Autonomous Vehicle Project
NASA Technical Reports Server (NTRS)
Stewart, Christopher
2016-01-01
The primary objective this summer is "evaluating standards for wireless architecture for the internet of things". The Internet of Things is the network of physical objects or "things" embedded with electronics, software, sensors and network connectivity which enables these objects to collect and exchange data and make decisions based on said data. This was accomplished by creating a semi-autonomous vehicle that takes advantage of multiple sensors, cameras, and onboard computers and combined them with a mesh network which enabled communication across large distances with little to no interruption. The mesh network took advantage of what is known as DTN - Disruption Tolerant Networking which according to NASA is the new communications protocol that is "the first step towards interplanetary internet." The use of DTN comes from the fact that it will store information if an interruption in communications is detected and even forward that information via other relays within range so that the data is not lost. This translates well into the project because as the car moves further away from whatever is sending it commands (in this case a joystick), the information can still be forwarded to the car with little to no loss of information thanks to the mesh nodes around the driving area.
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NASA Astrophysics Data System (ADS)
Barkhatov, N. A.; Revunov, S. E.; Vorobjev, V. G.; Yagodkina, O. I.
2018-03-01
The cause-and-effect relations of the dynamics of high-latitude geomagnetic activity (in terms of the AL index) and the type of the magnetic cloud of the solar wind are studied with the use of artificial neural networks. A recurrent neural network model has been created based on the search for the optimal physically coupled input and output parameters characterizing the action of a plasma flux belonging to a certain magnetic cloud type on the magnetosphere. It has been shown that, with IMF components as input parameters of neural networks with allowance for a 90-min prehistory, it is possible to retrieve the AL sequence with an accuracy to 80%. The successful retrieval of the AL dynamics by the used data indicates the presence of a close nonlinear connection of the AL index with cloud parameters. The created neural network models can be applied with high efficiency to retrieve the AL index, both in periods of isolated magnetospheric substorms and in periods of the interaction between the Earth's magnetosphere and magnetic clouds of different types. The developed model of AL index retrieval can be used to detect magnetic clouds.
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Application of non-coherent Doppler data types for deep space navigation
NASA Technical Reports Server (NTRS)
Bhaskaran, Shyam
1995-01-01
Recent improvements in computational capability and Deep Space Network technology have renewed interest in examining the possibility of using one-way Doppler data alone to navigate interplanetary spacecraft. The one-way data can be formulated as the standard differenced-count Doppler or as phase measurements, and the data can be received at a single station or differenced if obtained simultaneously at two stations. A covariance analysis is performed which analyzes the accuracy obtainable by combinations of one-way Doppler data and compared with similar results using standard two-way Doppler and range. The sample interplanetary trajectory used was that of the Mars Pathfinder mission to Mars. It is shown that differenced one-way data is capable of determining the angular position of the spacecraft to fairly high accuracy, but has relatively poor sensitivity to the range. When combined with single station data, the position dispersions are roughly an order of magnitude larger in range and comparable in angular position as compared to dispersions obtained with standard data two-way types. It was also found that the phase formulation is less sensitive to data weight variations and data coverage than the differenced-count Doppler formulation.
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Interplanetary CubeSat Navigational Challenges
NASA Technical Reports Server (NTRS)
Martin-Mur, Tomas J.; Gustafson, Eric D.; Young, Brian T.
2015-01-01
CubeSats are miniaturized spacecraft of small mass that comply with a form specification so they can be launched using standardized deployers. Since the launch of the first CubeSat into Earth orbit in June of 2003, hundreds have been placed into orbit. There are currently a number of proposals to launch and operate CubeSats in deep space, including MarCO, a technology demonstration that will launch two CubeSats towards Mars using the same launch vehicle as NASA's Interior Exploration using Seismic Investigations, Geodesy and Heat Transport (InSight) Mars lander mission. The MarCO CubeSats are designed to relay the information transmitted by the InSight UHF radio during Entry, Descent, and Landing (EDL) in real time to the antennas of the Deep Space Network (DSN) on Earth. Other CubeSatts proposals intend to demonstrate the operation of small probes in deep space, investigate the lunar South Pole, and visit a near Earth object, among others. Placing a CubeSat into an interplanetary trajectory makes it even more challenging to pack the necessary power, communications, and navigation capabilities into such a small spacecraft. This paper presents some of the challenges and approaches for successfully navigating CubeSats and other small spacecraft in deep space.
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A Space Weather Forecasting System with Multiple Satellites Based on a Self-Recognizing Network
Tokumitsu, Masahiro; Ishida, Yoshiteru
2014-01-01
This paper proposes a space weather forecasting system at geostationary orbit for high-energy electron flux (>2 MeV). The forecasting model involves multiple sensors on multiple satellites. The sensors interconnect and evaluate each other to predict future conditions at geostationary orbit. The proposed forecasting model is constructed using a dynamic relational network for sensor diagnosis and event monitoring. The sensors of the proposed model are located at different positions in space. The satellites for solar monitoring equip with monitoring devices for the interplanetary magnetic field and solar wind speed. The satellites orbit near the Earth monitoring high-energy electron flux. We investigate forecasting for typical two examples by comparing the performance of two models with different numbers of sensors. We demonstrate the prediction by the proposed model against coronal mass ejections and a coronal hole. This paper aims to investigate a possibility of space weather forecasting based on the satellite network with in-situ sensing. PMID:24803190
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A space weather forecasting system with multiple satellites based on a self-recognizing network.
Tokumitsu, Masahiro; Ishida, Yoshiteru
2014-05-05
This paper proposes a space weather forecasting system at geostationary orbit for high-energy electron flux (>2 MeV). The forecasting model involves multiple sensors on multiple satellites. The sensors interconnect and evaluate each other to predict future conditions at geostationary orbit. The proposed forecasting model is constructed using a dynamic relational network for sensor diagnosis and event monitoring. The sensors of the proposed model are located at different positions in space. The satellites for solar monitoring equip with monitoring devices for the interplanetary magnetic field and solar wind speed. The satellites orbit near the Earth monitoring high-energy electron flux. We investigate forecasting for typical two examples by comparing the performance of two models with different numbers of sensors. We demonstrate the prediction by the proposed model against coronal mass ejections and a coronal hole. This paper aims to investigate a possibility of space weather forecasting based on the satellite network with in-situ sensing.
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Zodiacal light as an indicator of interplanetary dust
NASA Technical Reports Server (NTRS)
Weinberg, J. L.; Sparrow, J. G.
1978-01-01
The most striking feature of the night sky in the tropics is the zodiacal light, which appears as a cone in the west after sunset and in the east before sunrise. It is caused by sunlight scattered or absorbed by particles in the interplanetary medium. The zodiacal light is the only source of information about the integrated properties of the whole ensemble of interplanetary dust. The brightness and polarization in different directions and at different colors can provide information on the optical properties and spatial distribution of the scattering particles. The zodiacal light arises from two independent physical processes related to the scattering of solar continuum radiation by interplanetary dust and to thermal emission which arises from solar radiation that is absorbed by interplanetary dust and reemitted mainly at infrared wavelengths. Attention is given to observational parameters of zodiacal light, the methods of observation, errors and absolute calibration, and the observed characteristics of zodiacal light.
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NASA Astrophysics Data System (ADS)
Nichols, J. D.; Badman, S. V.; Bagenal, F.; Bolton, S. J.; Bonfond, B.; Bunce, E. J.; Clarke, J. T.; Connerney, J. E. P.; Cowley, S. W. H.; Ebert, R. W.; Fujimoto, M.; Gérard, J.-C.; Gladstone, G. R.; Grodent, D.; Kimura, T.; Kurth, W. S.; Mauk, B. H.; Murakami, G.; McComas, D. J.; Orton, G. S.; Radioti, A.; Stallard, T. S.; Tao, C.; Valek, P. W.; Wilson, R. J.; Yamazaki, A.; Yoshikawa, I.
2017-08-01
We present the first comparison of Jupiter's auroral morphology with an extended, continuous, and complete set of near-Jupiter interplanetary data, revealing the response of Jupiter's auroras to the interplanetary conditions. We show that for ˜1-3 days following compression region onset, the planet's main emission brightened. A duskside poleward region also brightened during compressions, as well as during shallow rarefaction conditions at the start of the program. The power emitted from the noon active region did not exhibit dependence on any interplanetary parameter, though the morphology typically differed between rarefactions and compressions. The auroras equatorward of the main emission brightened over ˜10 days following an interval of increased volcanic activity on Io. These results show that the dependence of Jupiter's magnetosphere and auroras on the interplanetary conditions are more diverse than previously thought.
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Interplanetary scintillation observations of the solar wind close to the Sun and out of the ecliptic
NASA Technical Reports Server (NTRS)
Sime, D. G.
1983-01-01
A brief review is given of recent developments in the observation of the solar wind by the method of interplanetary scintillation. The emphasis is on observations of the velocity structure, the electron density and the effect of propagating disturbances in the interplanetary medium as detected principally by intensity and phase scintillation and by spectral broadening.
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The delivery of organic matter from asteroids and comets to the early surface of Mars
NASA Technical Reports Server (NTRS)
Flynn, G. J.
1996-01-01
Carbon delivered to the Earth by interplanetary dust particles may have been an important source of pre-biotic organic matter (Anders, 1989). Interplanetary dust is shown to deliver an order-of-magnitude higher surface concentration of carbon onto Mars than onto Earth, suggesting interplanetary dust may be an important source of carbon on Mars as well.
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Aquarius, a reusable water-based interplanetary human spaceflight transport
NASA Astrophysics Data System (ADS)
Adamo, Daniel R.; Logan, James S.
2016-11-01
Attributes of a reusable interplanetary human spaceflight transport are proposed and applied to example transits between the Earth/Moon system and Deimos, the outer moon of Mars. Because the transport is 54% water by mass at an interplanetary departure, it is christened Aquarius. In addition to supporting crew hydration/hygiene, water aboard Aquarius serves as propellant and as enhanced crew habitat radiation shielding during interplanetary transit. Key infrastructure and technology supporting Aquarius operations include pre-emplaced consumables and subsurface habitat at Deimos with crew radiation shielding equivalent to sea level on Earth, resupply in a selenocentric distant retrograde orbit, and nuclear thermal propulsion.
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NASA Technical Reports Server (NTRS)
Akasofu, S.-I.
1979-01-01
Akasofu (1979) has reported that the interplanetary parameter epsilon correlates reasonably well with the magnetospheric substorm index AE; in the first approximation, epsilon represents the solar wind coupled to the magnetosphere. The correlation between the interplanetary parameter, the auroral electrojet index and the ring current index is examined for three magnetic storms. It is shown that when the interplanetary parameter exceeds the amount that can be dissipated by the ionosphere in terms of the Joule heat production, the excess energy is absorbed by the ring current belt, producing an abnormal growth of the ring current index.
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The source of the electric field in the nightside magnetosphere
NASA Technical Reports Server (NTRS)
Stern, D. P.
1975-01-01
In the open magnetosphere model magnetic field lines from the polar caps connect to the interplanetary magnetic field and conduct an electric field from interplanetary space to the polar ionosphere. By examining the magnetic flux involved it is concluded that only slightly more than half of the magnetic flux in the polar caps belongs to open field lines and that such field lines enter or leave the magnetosphere through narrow elongated windows stretching the tail. These window regions are identified with the tail's boundary region and shift their position with changes in the interplanetary magnetic field, in particular when a change of interplanetary magnetic sector occurs. The circuit providing electric current in the magnetopause and the plasma sheet is extended across those windows; thus energy is drained from the interplanetary electric field and an electric potential drop is produced across the plasma sheet. The polar cap receives its electric field from interplanetary space on the day side from open magnetic field lines and on the night side from closed field lines leading to the plasma sheet. The theory described provides improved understanding of magnetic flux bookkeeping, of the origin of Birkeland currents, and of the boundary layer of the geomagnetic tail.
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NASA Technical Reports Server (NTRS)
Takahashi, H.; Yahagi, N.
1985-01-01
The spherical harmonic analysis of cosmic ray neutron data from the worldwide network neutron monitor stations during the years, 1966 to 1969 was carried out. The second zonal harmonic component obtained from the analysis corresponds to the Pole-Equator anisotropy of the cosmic ray neutron intensity. Such an anisotropy makes a semiannual variation. In addition to this, it is shown that the Pole-Equator anisotropy makes a variation depending on the interplanetary magnetic field (IMF) sector polarities around the passages of the IMF sector boundary. A mechanism to interpret these results is also discussed.
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Propagation Characteristics of Two Coronal Mass Ejections from the Sun Far into Interplanetary Space
DOE Office of Scientific and Technical Information (OSTI.GOV)
Zhao, Xiaowei; Liu, Ying D.; Hu, Huidong
Propagation of coronal mass ejections (CMEs) from the Sun far into interplanetary space is not well understood, due to limited observations. In this study we examine the propagation characteristics of two geo-effective CMEs, which occurred on 2005 May 6 and 13, respectively. Significant heliospheric consequences associated with the two CMEs are observed, including interplanetary CMEs (ICMEs) at the Earth and Ulysses , interplanetary shocks, a long-duration type II radio burst, and intense geomagnetic storms. We use coronagraph observations from SOHO /LASCO, frequency drift of the long-duration type II burst, in situ measurements at the Earth and Ulysses , and magnetohydrodynamicmore » propagation of the observed solar wind disturbances at 1 au to track the CMEs from the Sun far into interplanetary space. We find that both of the CMEs underwent a major deceleration within 1 au and thereafter a gradual deceleration when they propagated from the Earth to deep interplanetary space, due to interactions with the ambient solar wind. The results also reveal that the two CMEs interacted with each other in the distant interplanetary space even though their launch times on the Sun were well separated. The intense geomagnetic storm for each case was caused by the southward magnetic fields ahead of the CME, stressing the critical role of the sheath region in geomagnetic storm generation, although for the first case there is a corotating interaction region involved.« less
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NASA Astrophysics Data System (ADS)
Sultan, M. S.; Jules, A.; Marchese, P.; Damas, M. C.
2017-12-01
It is crucial to study space weather because severe interplanetary conditions can cause geomagnetic storms that may damage both space- and ground-based technological systems such as satellites, communication systems, and power grids. Interplanetary coronal mass ejections (ICMEs) and corotating interaction regions (CIRs) are the primary drivers of geomagnetic storms. As they travel through interplanetary space and reach geospace, their spatial structures change which can result in various geomagnetic effects. Therefore, studying these drivers and their structures is essential in order to better understand and mitigate their impact on technological systems, as well as to forecast geomagnetic storms. In this study, over 150 storms were cross-checked for both solar cycles (SC) 23 and 24. This data has revealed the most common interplanetary structures, i.e., sheath (Sh); magnetic cloud following a shock front (sMC); sheath region and magnetic cloud (Sh/MC); and corotating interaction regions (CIRs). Furthermore, plasma parameters as well as variation in the intensity and duration of storms resulting from different interplanetary structures are studied for their effect on geomagnetically induced currents (GICs), as well as for their effect on power grids. Although preliminary results for SC 23 indicate that storm intensity may play a dominant role for GICs, duration might also be a factor, albeit smaller. Results from both SC 23 and 24 are analyzed and compared, and should lead to an enhanced understanding of space weather consequences of interplanetary structures and their possible forecasting.
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Vacuum polarization near a distorted black hole
NASA Astrophysics Data System (ADS)
Frolov, V. P.; Alberto García, D.
1983-12-01
The vacuum polarization near a black hole distorted by the axially symmetric gravitational field of external matter is studied. The explicit expression for <φ2> at the pole of the distorted horizon is obtained. Also at Sección de Graduados, Escuela Superior de Ingeniería Mecánica y Eléctrica del IPN, México DF, México.
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TISSUE DISTRIBUTION OF INORGANIC ARSENIC (iAs) AND ITS METHYLATED METABOLITES IN MICE FOLLOWING ORAL ADMINISTRATION OF ARSENATE (AsV). E M Kenyon1, L M Del Razo2, and M F Hughes1. 1NHEERL, ORD, US EPA, RTP, NC, USA; 2CINVESTAV-IPN, Mexico City, Mexico.
The relationship o...
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ERIC Educational Resources Information Center
Margarita, Rasilla Cano; Argelia, Juárez Ruiz Lidia
2016-01-01
The IPN Oaxaca CIIDIR has a mission to train human resources to postgraduate level that contribute to sustainable regional development in the South-East of Mexico. This is a vulnerable region that boasts an important source of natural resources and a great social, economic and technological backwardness that is directly related to the educational…
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Infectious pancreatic necrosis: its detection and identification
Wolf, K.
1965-01-01
Ultimate control of infectious pancreatic necrosis (IPN) in hatcheries depends largely upon learning where the virus occurs. To detect the presence of virus either susceptible fish or susceptible fish cell cultures may be used as test systems. In modern virology, it is generally agreed that cell cultures are more convenient, are usually a much more sensitive test system, and allow more rapid determinations.
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Prevention and control of viral diseases of salmonids
Amend, Donald F.
1976-01-01
Three viral diseases of salmonids are of worldwide concern: infectious pancreatic necrosis (IPN) viral hemorrhagic septicemia (VHS), and infectious hematopoietic necrosis (IHN). Six principal approaches are being used to prevent or control these diseases: 1) preventing contact o the pathogen with the host, 2) environmental manipulation, 3) immunization, 4) chemotherapy, 5 selective breeding for disease resistance, and 6) reducing stress conditions which augment disease conditions. Preventing the introduction of a pathogen into a new stock of fish has been accomplished mainly by implementing stringent laws to prevent transport of infected fish into uninfected areas. Stocks of fish already infected are sometimes destroyed, and the hatchery is disinfected and restocked with fish free of specific pathogens. Environmental manipulation (elevated water temperature) has been successfully used to control IHN. Chemotherapeutics such as povidone-iodine for IPN and benzipyrene for IHN show promise of controlling mortalities; however, the practicality of using these drugs to eliminate the carrier fish has not been evaluated. Salmonids are capable of developing immune responses to viruses; however, development of effective vaccines, selective breeding for disease resistance, and identification of stress conditions which augment disease are still in the experimental phase.
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NASA Technical Reports Server (NTRS)
Ramamurti, R.; Ghia, U.; Ghia, K. N.
1988-01-01
A semi-elliptic formulation, termed the interacting parabolized Navier-Stokes (IPNS) formulation, is developed for the analysis of a class of subsonic viscous flows for which streamwise diffusion is neglible but which are significantly influenced by upstream interactions. The IPNS equations are obtained from the Navier-Stokes equations by dropping the streamwise viscous-diffusion terms but retaining upstream influence via the streamwise pressure-gradient. A two-step alternating-direction-explicit numerical scheme is developed to solve these equations. The quasi-linearization and discretization of the equations are carefully examined so that no artificial viscosity is added externally to the scheme. Also, solutions to compressible as well as nearly compressible flows are obtained without any modification either in the analysis or in the solution process. The procedure is applied to constricted channels and cascade passages formed by airfoils of various shapes. These geometries are represented using numerically generated curilinear boundary-oriented coordinates forming an H-grid. A hybrid C-H grid, more appropriate for cascade of airfoils with rounded leading edges, was also developed. Satisfactory results are obtained for flows through cascades of Joukowski airfoils.
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Noise Reduction and Correction in the IPNS Linac ESEM
NASA Astrophysics Data System (ADS)
Dooling, J. C.; Brumwell, F. R.; Donley, L.; McMichael, G. E.; Stipp, V. F.
2004-11-01
The Energy Spread and Energy Monitor (ESEM) is an on-line, non-intrusive diagnostic used to characterize the output beam from the 200-MHz, 50-MeV IPNS linac. The energy spread is determined from a 3-size, longitudinal emittance measurement; whereas the energy is derived from time of flight (TOF) analysis. Signals are detected on 50-ohm, stripline beam position monitors (BPMs) terminated in their characteristic impedance. Each BPM is constructed with four striplines: top, bottom, left and right. The ESEM signals are taken from the bottom stripline in four separate BPM locations in the 50-MeV transport line between the linac and the synchrotron. Deterministic linac noise is sampled before and after the 70-microsecond macropulse. The noise phasor is vectorially subtracted from the beam signal. Noise subtraction is required at several frequencies, especially the fundamental and fifth harmonics (200 MHz and 1 GHz). It is also necessary to correct for attenuation and dispersion in the co-axial signal cables. Presently, the analysis assumes a single particle distribution to determine energy and energy spread. Work is on-going to allow for more realistic longitudinal distributions to be included in the analysis.
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NASA Technical Reports Server (NTRS)
Englander, Jacob
2016-01-01
This set of tutorial slides is an introduction to the Evolutionary Mission Trajectory Generator (EMTG), NASA Goddard Space Flight Center's autonomous tool for preliminary design of interplanetary missions. This slide set covers the basics of creating and post-processing simple interplanetary missions in EMTG using both high-thrust chemical and low-thrust electric propulsion along with a variety of operational constraints.
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NASA Astrophysics Data System (ADS)
El-Sa'Ad, Leila
1989-12-01
Available from UMI in association with The British Library. Requires signed TDF. Epoxy resins exhibit many desirable properties which make them ideal subjects for use as matrices of composite materials in many commercial, military and space applications. However, due to their high cross-link density they are often brittle. Epoxy resin networks have been modified by incorporating tough, ductile thermoplastics. Such systems are referred to as Semi-Interpenetrating Polymer Networks (Semi-IPN). Systematic modification to the thermoplastics backbone allowed the morphology of the blend to be controlled from a homogeneous one-phase structure to fully separated structures. The moisture absorption by composites in humid environments has been found to lead to a deterioration in the physical and mechanical properties of the matrix. Therefore, in order to utilize composites to their full potential, their response to hot/wet environments must be known. The aims of this investigation were two-fold. Firstly, to study the effect of varying the temperature of exposure at different stages in the absorption process on the water absorption behaviour of a TGDDM/DDS epoxy resin system. Secondly, to study water absorption characteristics, under isothermal conditions, of Semi-Interpenetrating Polymer Networks possessing different morphologies, and develop a theoretical model to evaluate the diffusion coefficients of the two-phase structures. The mathematical treatment used in this analysis was based on Fick's second law of diffusion. Tests were performed on specimens immersed in water at 10 ^circ, 40^circ and 70^circC, their absorption behaviour and swelling behaviour, as a consequence of water absorption, were investigated. The absorption results of the variable temperature absorption tests indicated a saturation dependence on the absorption behaviour. Specimens saturated at a high temperature will undergo further absorption when transferred to a lower temperature. This behaviour was termed the "reverse thermal effect". The swelling results suggested that it is more tightly bound water in the polymer which takes part in the reverse thermal effect. The absorption results for the Semi-Interpenetrating Polymer Networks suggested that the two key parameters which affected the moisture uptake were the morphology of the network and the percentage of epoxy resin in the system.
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The Ambient and Perturbed Solar Wind: From the Sun to 1 AU
NASA Technical Reports Server (NTRS)
Steinolfson, R. S.
1997-01-01
The overall objective of the proposed research was to use numerical solutions of the magnetohydrodynamic (MHD) equations along with comparisons of the computed results with observations to study the following topics: (1) ambient solar wind solutions that extend from the solar surface to 1 astronomical unit (AU), contain closed magnetic structures near the Sun, and are consistent with observed values; (2) magnetic and plasma structures in coronal mass ejections (CMES) as they propagate to the interplanetary medium; (3) relation of MHD shocks to CMEs in the interplanetary medium; (4) interaction of MHD shocks with structures (such as other shocks, corotating interaction regions, current sheets) in the interplanetary plasma; and (5) simulations of observed interplanetary structures. A planned close collaboration with data analysts served to make the model more relevant to the data. The outcome of this research program is an improved understanding of the physical processes occurring in solar-generated disturbances in the interplanetary medium between the Sun and 1 AU.
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Geomagnetic response of interplanetary coronal mass ejections in the Earth's magnetosphere
NASA Astrophysics Data System (ADS)
Badruddin; Mustajab, F.; Derouich, M.
2018-05-01
A coronal mass ejections (CME) is the huge mass of plasma with embedded magnetic field ejected abruptly from the Sun. These CMEs propagate into interplanetary space with different speed. Some of them hit the Earth's magnetosphere and create many types of disturbances; one of them is the disturbance in the geomagnetic field. Individual geomagnetic disturbances differ not only in their magnitudes, but the nature of disturbance is also different. It is, therefore, desirable to understand these differences not only to understand the physics of geomagnetic disturbances but also to understand the properties of solar/interplanetary structures producing these disturbances of different magnitude and nature. In this work, we use the spacecraft measurements of CMEs with distinct magnetic properties propagating in the interplanetary space and generating disturbances of different levels and nature. We utilize their distinct plasma and field properties to search for the interplanetary parameter(s) playing important role in influencing the geomagnetic response of different coronal mass ejections.
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NASA Astrophysics Data System (ADS)
Ni, Y. Y.
2018-03-01
We study the interplanetary causes of intense geomagnetic storms (Dst ≤ -100 nT) and the corresponding Geomagnetically Induced Current (GIC) events occurred in Ling’ao nuclear power station, Guangdong during the declining phase of solar cycle 23 (2003–2006). The result shows that sMC (a magnetic cloud with a shock), SH (sheath) and SH+MC (a sheath followed by a magnetic cloud) are the three most common interplanetary structures responsible for the storms which will cause GIC events in this period. As an interplanetary structure, CIR (corotating interaction regions) also plays an important role, however, the CIR-driven storms have a relatively minor effect to the GIC. Among the interplanetary parameters, the solar wind velocity and the southward component of the IMF (interplanetary magnetic field) are more important than solar wind density and the temperature to a geomagnetic storm and GIC.
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MACHETE: Environment for Space Networking Evaluation
NASA Technical Reports Server (NTRS)
Jennings, Esther H.; Segui, John S.; Woo, Simon
2010-01-01
Space Exploration missions requires the design and implementation of space networking that differs from terrestrial networks. In a space networking architecture, interplanetary communication protocols need to be designed, validated and evaluated carefully to support different mission requirements. As actual systems are expensive to build, it is essential to have a low cost method to validate and verify mission/system designs and operations. This can be accomplished through simulation. Simulation can aid design decisions where alternative solutions are being considered, support trade-studies and enable fast study of what-if scenarios. It can be used to identify risks, verify system performance against requirements, and as an initial test environment as one moves towards emulation and actual hardware implementation of the systems. We describe the development of Multi-mission Advanced Communications Hybrid Environment for Test and Evaluation (MACHETE) and its use cases in supporting architecture trade studies, protocol performance and its role in hybrid simulation/emulation. The MACHETE environment contains various tools and interfaces such that users may select the set of tools tailored for the specific simulation end goal. The use cases illustrate tool combinations for simulating space networking in different mission scenarios. This simulation environment is useful in supporting space networking design for planned and future missions as well as evaluating performance of existing networks where non-determinism exist in data traffic and/or link conditions.
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TPS Ablator Technologies for Interplanetary Spacecraft
NASA Technical Reports Server (NTRS)
Curry, Donald M.
2004-01-01
This slide presentation reviews the status of Thermal Protection System (TPS) Ablator technologies and the preparation for use in interplanetary spacecraft. NASA does not have adequate TPS ablatives and sufficient selection for planned missions. It includes a comparison of shuttle and interplanetary TPS requirements, the status of mainline TPS charring ablator materials, a summary of JSC SBIR accomplishments in developing advanced charring ablators and the benefits of SBIR Ablator/fabrication technology.
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Molecular dynamics studies of interpenetrating polymer networks for actuator devices
NASA Astrophysics Data System (ADS)
Brandell, Daniel; Kasemägi, Heiki; Citérin, Johann; Vidal, Frédéric; Chevrot, Claude; Aabloo, Alvo
2008-03-01
Molecular Dynamics (MD) techniques have been used to study the structure and dynamics of a model system of an interpenetrating polymer (IPN) network for actuator devices. The systems simulated were generated using a Monte Carlo-approach, and consisted of poly(ethylene oxide) (PEO) and poly(butadiene) (PB) in a 80-20 percent weight ratio immersed into propylene carbonate (PC) solutions of LiClO 4. The total polymer content was 32%, in order to model experimental conditions. The dependence of LiClO 4 concentration in PC has been studied by studying five different concentrations: 0.25, 0.5, 0.75, 1.0 and 1.25 M. After equilibration, local structural properties and dynamical features such as phase separation, coordination, cluster stability and ion conductivity were studied. In an effort to study the conduction processes more carefully, external electric fields of 1×10 6 V/m and 5×10 6 V/m has been applied to the simulation boxes. A clear relationship between the degree of local phase separation and ion mobility is established. It is also shown that although the ion pairing increases with concentration, there are still significantly more potential charge carriers in the higher concentrated systems, while concentrations around 0.5-0.75 M of LiClO 4 in PC seem to be favorable in terms of ion mobility. Furthermore, the anions exhibit higher conductivity than the cations, and there are tendencies to solvent drag from the PC molecules.
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DOE Office of Scientific and Technical Information (OSTI.GOV)
Kozai, M.; Munakata, K.; Kato, C.
2016-07-10
We analyze the galactic cosmic ray (GCR) density and its spatial gradient in Forbush Decreases (FDs) observed with the Global Muon Detector Network (GMDN) and neutron monitors (NMs). By superposing the GCR density and density gradient observed in FDs following 45 interplanetary shocks (IP-shocks), each associated with an identified eruption on the Sun, we infer the average spatial distribution of GCRs behind IP-shocks. We find two distinct modulations of GCR density in FDs, one in the magnetic sheath and the other in the coronal mass ejection (CME) behind the sheath. The density modulation in the sheath is dominant in themore » western flank of the shock, while the modulation in the CME ejecta stands out in the eastern flank. This east–west asymmetry is more prominent in GMDN data responding to ∼60 GV GCRs than in NM data responding to ∼10 GV GCRs, because of the softer rigidity spectrum of the modulation in the CME ejecta than in the sheath. The geocentric solar ecliptic- y component of the density gradient, G {sub y}, shows a negative (positive) enhancement in FDs caused by the eastern (western) eruptions, while G {sub z} shows a negative (positive) enhancement in FDs caused by the northern (southern) eruptions. This implies that the GCR density minimum is located behind the central flank of IP-shocks and propagating radially outward from the location of the solar eruption. We also confirmed that the average G {sub z} changes its sign above and below the heliospheric current sheet, in accord with the prediction of the drift model for the large-scale GCR transport in the heliosphere.« less
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The Global Survey Method Applied to Ground-level Cosmic Ray Measurements
NASA Astrophysics Data System (ADS)
Belov, A.; Eroshenko, E.; Yanke, V.; Oleneva, V.; Abunin, A.; Abunina, M.; Papaioannou, A.; Mavromichalaki, H.
2018-04-01
The global survey method (GSM) technique unites simultaneous ground-level observations of cosmic rays in different locations and allows us to obtain the main characteristics of cosmic-ray variations outside of the atmosphere and magnetosphere of Earth. This technique has been developed and applied in numerous studies over many years by the Institute of Terrestrial Magnetism, Ionosphere and Radiowave Propagation (IZMIRAN). We here describe the IZMIRAN version of the GSM in detail. With this technique, the hourly data of the world-wide neutron-monitor network from July 1957 until December 2016 were processed, and further processing is enabled upon the receipt of new data. The result is a database of homogeneous and continuous hourly characteristics of the density variations (an isotropic part of the intensity) and the 3D vector of the cosmic-ray anisotropy. It includes all of the effects that could be identified in galactic cosmic-ray variations that were caused by large-scale disturbances of the interplanetary medium in more than 50 years. These results in turn became the basis for a database on Forbush effects and interplanetary disturbances. This database allows correlating various space-environment parameters (the characteristics of the Sun, the solar wind, et cetera) with cosmic-ray parameters and studying their interrelations. We also present features of the coupling coefficients for different neutron monitors that enable us to make a connection from ground-level measurements to primary cosmic-ray variations outside the atmosphere and the magnetosphere. We discuss the strengths and weaknesses of the current version of the GSM as well as further possible developments and improvements. The method developed allows us to minimize the problems of the neutron-monitor network, which are typical for experimental physics, and to considerably enhance its advantages.
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NASA Technical Reports Server (NTRS)
Riha, Andrew P.
2005-01-01
As humans and robotic technologies are deployed in future constellation systems, differing traffic services will arise, e.g., realtime and non-realtime. In order to provide a quality of service framework that would allow humans and robotic technologies to interoperate over a wide and dynamic range of interactions, a method of classifying data as realtime or non-realtime is needed. In our paper, we present an approach that leverages the Consultative Committee for Space Data Systems (CCSDS) Advanced Orbiting Systems (AOS) data link protocol. Specifically, we redefine the AOS Transfer Frame Replay Flag in order to provide an automated store-and-forward approach on a per-service basis for use in the next-generation Interplanetary Network. In addition to addressing the problem of intermittent connectivity and associated services, we propose a follow-on methodology for prioritizing data through further modification of the AOS Transfer Frame.
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Interplanetary Small Satellite Conference 2017 Program
NASA Technical Reports Server (NTRS)
Dalle, Derek Jordan
2017-01-01
The Interplanetary Small Satellite Conference will be held at San Jose State University on May 1 and 2, 2017. The program attached here contains logistical information for attendees, the agenda, and abstracts of the conference presentations. All abstracts were reviewed by their authors' home institute and approved for public release prior to inclusion in the program booklet. The ISSC explores mission concepts, emerging technologies, and fosters outside the box thinking critical to future interplanetary small satellite missions.
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Research in space physics at the University of Iowa
NASA Technical Reports Server (NTRS)
Vanallen, J. A.
1976-01-01
Energetic particles in outer space and their relationship to electric, magnetic, and electromagnetic fields associated with the earth, sun, moon, and planets, and the interplanetary medium are investigated. Special attention was given to observations of earth and moon satellites and interplanetary spacecraft; phenomenological analysis and interpretation were emphasized. Data also cover ground based on radio astronomical and optical techniques and theoretical problems in plasma physics as revelant to solar planetary and interplanetary phenomena.
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Hydromagnetic waves, turbulence, and collisionless processes in the interplanetary medium
NASA Technical Reports Server (NTRS)
Barnes, A.
1983-01-01
An extended discussion is conducted concerning the origin and evolution of interplanetary hydromagnetic waves and turbulence, and their influence on the large scale dynamics of the solar wind. The solar wind is at present the preeminent medium for the study of hydromagnetic waves and turbulence, providing an opportunity for advancement of understanding of the most fundamental processes of the astrophysical plasmas. All interplanetary fluctuations whose time scale is observed to be greater than 1 sec can be regarded as hydromagnetic fluctuations. It has been found to be simplest, and generally very satisfactory, to model interplanetary variations as fluctuations in an MHD fluid. Attention is given to the classification of wave modes, geometrical hydromagnetics, Alfven wave pressure, rugged invariants, and the kinetic theory of collisionless processes.
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International Launch Vehicle Selection for Interplanetary Travel
NASA Technical Reports Server (NTRS)
Ferrone, Kristine; Nguyen, Lori T.
2010-01-01
In developing a mission strategy for interplanetary travel, the first step is to consider launch capabilities which provide the basis for fundamental parameters of the mission. This investigation focuses on the numerous launch vehicles of various characteristics available and in development internationally with respect to upmass, launch site, payload shroud size, fuel type, cost, and launch frequency. This presentation will describe launch vehicles available and in development worldwide, then carefully detail a selection process for choosing appropriate vehicles for interplanetary missions focusing on international collaboration, risk management, and minimization of cost. The vehicles that fit the established criteria will be discussed in detail with emphasis on the specifications and limitations related to interplanetary travel. The final menu of options will include recommendations for overall mission design and strategy.
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STIP Symposium on Physical Interpretation of Solar/Interplanetary and Cometary Intervals
NASA Technical Reports Server (NTRS)
Wu, S. T.
1987-01-01
The study of travelling interplanetary phenomena has continued over a period of years. The STIP (Study of Travelling Interplanetary Phenomena) Symposium on Physical Interpretation of Solar/Interplanetary and Cometary Intervals was held in Huntsville, Alabama, on May 12-15, 1987, the first of these meetings to be held in the United States. The Symposium's objective was to coordinate and disseminate new science gained from the recent solar-terrestrial and cometary intervals which can be used to better understand the linkage of physical events to the Sun's vagaries (flares, coronal holes, eruptive prominences) from their initial detection to their consequence. Fifty-one presentations were made during the four-day period. Abstracts of these reports are included as Appendix A.
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Interplanetary laser ranging - an emerging technology for planetary science missions
NASA Astrophysics Data System (ADS)
Dirkx, D.; Vermeersen, L. L. A.
2012-09-01
Interplanetary laser ranging (ILR) is an emerging technology for very high accuracy distance determination between Earth-based stations and spacecraft or landers at interplanetary distances. It has evolved from laser ranging to Earth-orbiting satellites, modified with active laser transceiver systems at both ends of the link instead of the passive space-based retroreflectors. It has been estimated that this technology can be used for mm- to cm-level accuracy range determination at interplanetary distances [2, 7]. Work is being performed in the ESPaCE project [6] to evaluate in detail the potential and limitations of this technology by means of bottom-up laser link simulation, allowing for a reliable performance estimate from mission architecture and hardware characteristics.
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Interactions between biomaterials and the sclera: Implications on myopia progression
NASA Astrophysics Data System (ADS)
Su, James
Myopia prevalence has steadily climbed worldwide in recent decades with the most dramatic impact in East Asian countries. Treatments such as eyeglasses, contact lenses, and laser surgery for the refractive error are widely available, but none cures the underlying cause. In progressive high myopia, invasive surgical procedures using a scleral buckle for mechanical support are performed since the patient is at risk of becoming blind. The treatment outcome is highly dependent on the surgeon's skills and the patient's myopia progression rate, with limited choices in buckling materials. This dissertation, in four main studies, represents efforts made to control high myopia progression through the exploration and development of biomaterials that influence scleral growth. First, mRNA expression levels of the chick scleral matrix metalloproteinases, tissue-inhibitor of matrix metalloproteinases, and transforming growth factor-beta 2 were assessed for temporal and defocus power effects. The first study elucidated the roles that these factors play in scleral growth regulation and suggested potential motifs that can be incorporated in future biomaterials design. Second, poly(vinyl-pyrrolidone) as injectable gels and poly(2-hydroxyethyl methacrylate) as solid strips were implanted in chicks to demonstrate the concept of posterior pole scleral reinforcements. This second study found that placing appropriate biomaterials at the posterior pole of the eye could directly influence scleral remodeling by interacting with the host cells. Both studies advanced the idea that scleral tissue remodeling could be potentially controlled by well-designed biomaterials. These findings led to the exploration of biomimetic hydrogels comprising enzymatically-degradable semi-interpenetrating polymer networks (edsIPNs) to determine their biocompatibility and effects on the chick posterior eye wall. This third study demonstrated the feasibility of stimulating scleral growth by applying biomimetic injectable materials. Fourth, the muscarinic antagonist drug, atropine, was encapsulated within the edsIPNs and delivered to the chick eye posterior pole to evaluate the local effect of atropine release. This fourth study offered an alternative method of ocular drug delivery for treatment of myopia, with the potential to elucidate the actual location of the inhibitive effect of atropine on myopia progression. In summary, this dissertation contributes to the design and use of biomaterials specific to myopia therapy and adds novel insights to scleral tissue engineering.
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Zhou, Hong; Malik, Malika Amattullah; Arab, Aarthi; Hill, Matthew Thomas; Shikanov, Ariella
2015-01-01
Various toxicants, drugs and their metabolites carry potential ovarian toxicity. Ovarian follicles, the functional unit of the ovary, are susceptible to this type of damage at all stages of their development. However, despite of the large scale of potential negative impacts, assays that study ovarian toxicity are limited. Exposure of cultured ovarian follicles to toxicants of interest served as an important tool for evaluation of toxic effects for decades. Mouse follicles cultured on the bottom of a culture dish continue to serve an important approach for mechanistic studies. In this paper, we demonstrated the usefulness of a hydrogel based 3-dimensional (3D) mouse ovarian follicle culture as a tool to study ovarian toxicity in a different setup. The 3D in vitro culture, based on fibrin alginate interpenetrating network (FA-IPN), preserves the architecture of the ovarian follicle and physiological structure-function relationship. We applied the novel 3D high-throughput (HTP) in vitro ovarian follicle culture system to study the ovotoxic effects of an anti-cancer drug, Doxorobucin (DXR). The fibrin component in the system is degraded by plasmin and appears as a clear circle around the encapsulated follicle. The degradation area of the follicle is strongly correlated with follicle survival and growth. To analyze fibrin degradation in a high throughput manner, we created a custom MATLAB® code that converts brightfield micrographs of follicles encapsulated in FA-IPN to binary images, followed by image analysis. We did not observe any significant difference between manually processed images to the automated MATLAB® method, thereby confirming that the automated program is suitable to measure fibrin degradation to evaluate follicle health. The cultured follicles were treated with DXR at concentrations ranging from 0.005 nM to 200 nM, corresponding to the therapeutic plasma levels of DXR in patients. Follicles treated with DXR demonstrated decreased survival rate in greater DXR concentrations. We observed partial follicle survival of 35% ± 3% (n = 80) in 0.01nM treatment and 48% ± 2% (n = 92) in 0.005nM, which we identified as the IC50 for secondary follicles. In summary, we established a 3D in vitro ovarian follicle culture system that could be used in an HTP approach to measure toxic effects on ovarian follicles. PMID:26451950
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NASA Astrophysics Data System (ADS)
Ricker, George R.
1990-08-01
The Energetic Transient Array (ETA) is a concept for a dedicated interplanetary network of ~40 microsatellites (``space buoys'') deployed in an ~1 AU radius solar orbit for the observation of cosmic gamma ray bursts (GRBs). Such a network is essential for the determination of highly accurate (~0.1 arc sec) error boxes for GRBs. For each of ~100 bursts which would be detectable per year of observation by such a network, high resolution (ΔE/E ~0.2% at 1 MeV) spectra could be obtained through the use of passively-cooled Ge gamma-ray detectors. Stabilization of each microsatellite would be achieved by a novel technique based on the radiation pressure exerted on ``featherable'' solar paddles. Because of the simplicity of the microsats, as well as the economics of mass production and the failure tolerance of such a network of independent satellites, a unit cost of ~$250 K per microsat can be anticipated. Should such a project be undertaken in the mid 1990's, possibly as an International mission, it should be possible to have a fully functional array of satellites in place before the end of the decade for a total cost of ~$20M, exclusive of launcher fees.
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Remote observing with NASA's Deep Space Network
NASA Astrophysics Data System (ADS)
Kuiper, T. B. H.; Majid, W. A.; Martinez, S.; Garcia-Miro, C.; Rizzo, J. R.
2012-09-01
The Deep Space Network (DSN) communicates with spacecraft as far away as the boundary between the Solar System and the interstellar medium. To make this possible, large sensitive antennas at Canberra, Australia, Goldstone, California, and Madrid, Spain, provide for constant communication with interplanetary missions. We describe the procedures for radioastronomical observations using this network. Remote access to science monitor and control computers by authorized observers is provided by two-factor authentication through a gateway at the Jet Propulsion Laboratory (JPL) in Pasadena. To make such observations practical, we have devised schemes based on SSH tunnels and distributed computing. At the very minimum, one can use SSH tunnels and VNC (Virtual Network Computing, a remote desktop software suite) to control the science hosts within the DSN Flight Operations network. In this way we have controlled up to three telescopes simultaneously. However, X-window updates can be slow and there are issues involving incompatible screen sizes and multi-screen displays. Consequently, we are now developing SSH tunnel-based schemes in which instrument control and monitoring, and intense data processing, are done on-site by the remote DSN hosts while data manipulation and graphical display are done at the observer's host. We describe our approaches to various challenges, our experience with what worked well and lessons learned, and directions for future development.
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Interplanetary Magnetic Field Guiding Relativistic Particles
NASA Technical Reports Server (NTRS)
Masson, S.; Demoulin, P.; Dasso, S.; Klein, K. L.
2011-01-01
The origin and the propagation of relativistic solar particles (0.5 to few Ge V) in the interplanetary medium remains a debated topic. These relativistic particles, detected at the Earth by neutron monitors have been previously accelerated close to the Sun and are guided by the interplanetary magnetic field (IMF) lines, connecting the acceleration site and the Earth. Usually, the nominal Parker spiral is considered for ensuring the magnetic connection to the Earth. However, in most GLEs the IMF is highly disturbed, and the active regions associated to the GLEs are not always located close to the solar footprint of the nominal Parker spiral. A possible explanation is that relativistic particles are propagating in transient magnetic structures, such as Interplanetary Coronal Mass Ejections (ICMEs). In order to check this interpretation, we studied in detail the interplanetary medium where the particles propagate for 10 GLEs of the last solar cycle. Using the magnetic field and the plasma parameter measurements (ACE/MAG and ACE/SWEPAM), we found widely different IMF configurations. In an independent approach we develop and apply an improved method of the velocity dispersion analysis to energetic protons measured by SoHO/ERNE. We determined the effective path length and the solar release time of protons from these data and also combined them with the neutron monitor data. We found that in most of the GLEs, protons propagate in transient magnetic structures. Moreover, the comparison between the interplanetary magnetic structure and the interplanetary length suggest that the timing of particle arrival at Earth is dominantly determined by the type of IMF in which high energetic particles are propagating. Finally we find that these energetic protons are not significantly scattered during their transport to Earth.
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The interplanetary and solar magnetic field sector structures, 1962 - 1968
NASA Technical Reports Server (NTRS)
Jones, D. E.
1972-01-01
The interplanetary magnetic field sector structure was observed from late 1962 through 1968. During this time it has been possible to study the manner in which the sector pattern and its relation to the photospheric magnetic field configuration changes from solar minimum to solar maximum. Observations were also made relating sector boundaries to specific regions on the solar disk. These and other observations related to the solar origin of the interplanetary field are briefly reviewed.
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Wan, Q; Masters, R C; Lidzey, D; Abrams, K J; Dapor, M; Plenderleith, R A; Rimmer, S; Claeyssens, F; Rodenburg, C
2016-12-01
Recently developed detectors can deliver high resolution and high contrast images of nanostructured carbon based materials in low voltage scanning electron microscopes (LVSEM) with beam deceleration. Monte Carlo Simulations are also used to predict under which exact imaging conditions purely compositional contrast can be obtained and optimised. This allows the prediction of the electron signal intensity in angle selective conditions for back-scattered electron (BSE) imaging in LVSEM and compares it to experimental signals. Angle selective detection with a concentric back scattered (CBS) detector is considered in the model in the absence and presence of a deceleration field, respectively. The validity of the model prediction for both cases was tested experimentally for amorphous C and Cu and applied to complex nanostructured carbon based materials, namely a Poly(N-isopropylacrylamide)/Poly(ethylene glycol) Diacrylate (PNIPAM/PEGDA) semi-interpenetration network (IPN) and a Poly(3-hexylthiophene-2,5-diyl) (P3HT) film, to map nano-scale composition and crystallinity distribution by avoiding experimental imaging conditions that lead to a mixed topographical and compositional contrast. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.
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Velocity Distributions of Interplanetary Dust Derived from Astronomical Sky Spectra
NASA Astrophysics Data System (ADS)
Huestis, D. L.; Ali, S.; Cosby, P. C.; Slanger, T. G.
2001-11-01
Characterization of interplanetary dust is important for understanding the creation by accretion of planets and moons, the development of planetary atmospheres, and, potentially, for the initiation of prebiotic chemistry. The recent COBE mission has provided a profile in ecliptic coordinates of the distribution of interplanetary dust particles through their thermal infrared emission. Additional information about interplanetary dust can be extracted from its visible spectrum of scattered sunlight, called Zodiacal Light. Night sky spectra taken at large-aperture telescopes using high-resolution echelle spectrographs reveal Fraunhofer absorption features in the Zodiacal Light spectrum of scattered sunlight, a nuisance in subtraction from the spectrum of the extraterrestrial object under investigation. We are analyzing the intensity modulations and Doppler shifts of solar Fraunhofer absorption lines in the Zodiacal Light component of sky spectra, donated by collaborating astronomers using Keck/HIRES and other high-performance astronomical facilities. Our objectives include velocity distributions of interplanetary dust and improved separation of terrestrial and extraterrestrial sources in sky spectra. Participation of S. Ali was made possible by a grant from the NSF Physics Research Experiences for Undergraduates (REU) program.
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Flux rope evolution in interplanetary coronal mass ejections: the 13 May 2005 event
NASA Astrophysics Data System (ADS)
Manchester, W. B., IV; van der Holst, B.; Lavraud, B.
2014-06-01
Coronal mass ejections (CMEs) are a dramatic manifestation of solar activity that release vast amounts of plasma into the heliosphere, and have many effects on the interplanetary medium and on planetary atmospheres, and are the major driver of space weather. CMEs occur with the formation and expulsion of large-scale magnetic flux ropes from the solar corona, which are routinely observed in interplanetary space. Simulating and predicting the structure and dynamics of these interplanetary CME magnetic fields are essential to the progress of heliospheric science and space weather prediction. We discuss the simulation of the 13 May 2005 CME event in which we follow the propagation of a flux rope from the solar corona to beyond Earth orbit. In simulating this event, we find that the magnetic flux rope reconnects with the interplanetary magnetic field, to evolve to an open configuration and later reconnects to reform a twisted structure sunward of the original rope. Observations of the 13 May 2005 CME magnetic field near Earth suggest that such a rearrangement of magnetic flux by reconnection may have occurred.
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Interplanetary density models as inferred from solar Type III bursts
NASA Astrophysics Data System (ADS)
Oppeneiger, Lucas; Boudjada, Mohammed Y.; Lammer, Helmut; Lichtenegger, Herbert
2016-04-01
We report on the density models derived from spectral features of solar Type III bursts. They are generated by beams of electrons travelling outward from the Sun along open magnetic field lines. Electrons generate Langmuir waves at the plasma frequency along their ray paths through the corona and the interplanetary medium. A large frequency band is covered by the Type III bursts from several MHz down to few kHz. In this analysis, we consider the previous empirical density models proposed to describe the electron density in the interplanetary medium. We show that those models are mainly based on the analysis of Type III bursts generated in the interplanetary medium and observed by satellites (e.g. RAE, HELIOS, VOYAGER, ULYSSES,WIND). Those models are confronted to stereoscopic observations of Type III bursts recorded by WIND, ULYSSES and CASSINI spacecraft. We discuss the spatial evolution of the electron beam along the interplanetary medium where the trajectory is an Archimedean spiral. We show that the electron beams and the source locations are depending on the choose of the empirical density models.
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Observations of interactions between interplanetary and geomagnetic fields
NASA Technical Reports Server (NTRS)
Burch, J. L.
1973-01-01
Magnetospheric effects associated with variations of the north-south component of the interplanetary magnetic field are examined in light of recent recent experimental and theoretical results. Although the occurrence of magnetospheric substorms is statistically related to periods of southward interplanetary magnetic field, the details of the interaction are not understood. In particular, attempts to separate effects resulting directly from the interaction between the interplanetary and geomagnetic fields from those associated with substorms have produced conflicting results. The transfer of magnetic flux from the dayside to the nightside magnetosphere is evidenced by equatorward motion of the polar cusp and increases of the magnetic energy density in the lobes of the geomagnetic tail. The formation of a macroscopic X-type neutral line at tail distances less than 35 R sub E appears to be a substorm phenomenon.
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NASA Astrophysics Data System (ADS)
Levasseur-Regourd, Anny-Chantal; Gaboriaud, Alain; Buil, Christian; Ressouche, Antoine; Lasue, J.; Palun, Adrien; Apper, Fabien; Elmaleh, Marc
Intensity and linear polarization observations of the solar light scattered by interplanetary dust, the so-called zodiacal light, provide information on properties of the dust particles, such as their spatial density, local changes, morphology and albedo. Earth-based polarimetric observations, with a resolution of 5° or more, have been used to derive the polarization phase curve of interplanetary dust particles and to establish that the polarization at 90° phase angle increases with increasing solar distance, at least up to 1.5 au in the ecliptic, while the albedo decreases [1, 2]. Analysis of such studies will be revisited. Numerical simulations of the polarimetric behavior of interplanetary dust particles strongly suggest that, in the inner solar system, interplanetary dust particles consist of absorbing (e.g., organic compounds) and less absorbing (e.g., silicates) materials, that radial changes originate in a decrease of organics with decreasing solar distance (probably due to alteration processes), and that a significant fraction of the interplanetary dust is of cometary origin, in agreement with dynamical studies [3, 4]. The polarimetric behaviors of interplanetary dust and cometary dust particles seem to present striking similarities. The properties of cometary dust particles, as derived from remote polarimetric observations of comets including 67P/Churyumov-Gerasimenko, the target of the Rosetta rendezvous mission, at various wavelengths, will be summarized [5, 6]. The ground truth expected from Rosetta dust experiments, i.e., MIDAS, COSIMA, GIADA, about dust particles’ morphology, composition, and evolution (with distance to the nucleus before Philae release and with distance to the Sun before and after perihelion passage) over the year and a half of nominal mission, will be discussed. Finally, the Eye-Sat nanosatellite will be presented. This triple cubesat, developed by students from engineering schools working as interns at CNES, is to be launched in 2016 [7]. Its main purpose is to study the zodiacal light intensity and polarization from a Sun-synchronous orbit, for the first time at the high spatial resolution of 1° over a wide portion of the sky and at four different wavelengths (in the visible and near-IR domains). The instrumental choices and new on-board technologies will be summarized, together with the results that may be expected on local properties of the interplanetary dust particles and thus on their similarities and differences with cometary dust particles. Support from CNES is warmly acknowledged. [1] Leinert, C., Bowyer, S., Haikala, L.K., et al. The 1997 reference of diffuse night sky brightness, Astron. Astrophys. Supp., 127, 1-99, 1998. [2] Levasseur-Regourd, A.C., Mann, I., Dumont, R., et al. Optical and thermal properties of interplanetary dust. In Interplanetary dust (Grün, E. et al. Eds), 57-94, Springer-Verlag, Berlin, 2001. [3] Lasue, J., Levasseur-Regourd, A.C., Fray, N., et al. Inferring the interplanetary dust properties from remote observations and simulations, Astron. Astrophys., 473, 641-649, 2007. [4] Nesvorny, D., Jenniskens, P., Levison, H.F., et al. Cometary origin of the zodiacal cloud and carbonaceous micrometeorites: implications for hot debris disks. Astrophys. J. 713, 816-836, 2010. [5] Levasseur-Regourd, A.C., Mukai, T., Lasue, J., et al. Physical properties of cometary and interplanetary dust, Planet. Space Sci., 55, 1010-1020, 2007. [6] Hadamcik, E., Sen, A.K., Levasseur-Regourd, A.C., et al., Astron. Astrophys., 517, A86, 2010. [7] CNES internal report. Eye-Sat end of phase A internal review, EYESAT-PR-0-022-CNES, 2013.
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NASA Technical Reports Server (NTRS)
Hooke, A. J.
2000-01-01
Architectural design of the interplanetary internet is now underway and prototype flight testing of some of the candidate protocols is anticipated within a year. This talk will describe the current status of the project.
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NASA Technical Reports Server (NTRS)
Beckley, L. E.
1977-01-01
Progress in various space flight research programs is reported. Emphasis is placed on X-ray astronomy and interplanetary plasma physics. Topics covered include: infrared astronomy, long base line interferometry, geological spectroscopy, space life science experiments, atmospheric physics, and space based materials and structures research. Analysis of galactic and extra-galactic X-ray data from the Small Astronomy Satellite (SAS-3) and HEAO-A and interplanetary plasma data for Mariner 10, Explorers 47 and 50, and Solrad is discussed.
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NASA Astrophysics Data System (ADS)
Ballatore, Paola
2003-10-01
The paper [2002] (the paper commented) shows that the statistical significance of the correlations between the interplanetary parameters and the geomagnetic indices (Kp or Dst) is generally less significant during the fastest solar wind. On the other hand, at these fast solar wind periods, the significance of the Kp versus Dst correlation is equal to or higher than during slower solar wind. These results, together with further observations related to substorm periods and with previously published findings, are interpreted in terms of a difference in the interplanetary-magnetospheric coupling for solar wind faster or slower than a certain threshold (identified between about 500 and 600 km/s). Specifically, it is suggested that a possible linear approximation of the geomagnetic-interplanetary coupling is more appropriate during solar wind speed (Vsw) slower than this threshold, being nonlinear processes more dominant during the fastest speeds. This reply highlights that the correlation coefficients shown by [2003] are in agreement with these findings. In addition, Wang and Chao show that the statistical significance of the difference between the correlation coefficients for Vsw ≥ 550 km/s and those for Vsw < 550 km/s would indicate that the interplanetary-geomagnetic correlations during the fastest speeds are not significantly different from those at slower Vsw ranges. Here we give evidence of the fact that according to the common definition of this parameter, the calculation of the significance of the difference between two correlation coefficients made by Wang and Chao is wrong. Moreover, Wang and Chao recalculate the correlations between the interplanetary parameters and the ΔDst instead of Dst; in fact they note that the time derivative of this index (not the index itself) is driven by the interplanetary medium. Here we note that on the contrary, they show that the correlation coefficients between interplanetary parameters and Dst are larger than those obtained using ΔDst and we suggest a possible interpretation in terms of nonlinearity.
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Yang, Chaochao; Xue, Rui; Zhang, Qingsong; Yang, Shulin; Liu, Pengfei; Chen, Li; Wang, Ke; Zhang, Xiaoyong; Wei, Yen
2017-12-01
High antibacterial and skin-like hydrogels have always been the perfect wound dressing for human to protect wound from infection. Here, based on silk sericin, we design a series of nanoclay lithium magnesium silicate hydrate (LMSH) cross-linked semi-IPN sericin/poly(NIPAm/LMSH) (HSP) nanocomposite hydrogels and demonstrate advantages in serving as antibacterial wound dressing in comparison with gauze. Firstly, the effect of mass ratios of sericin/(sericin+NIPAm) upon pore structure, feasibility of mechanics and gas permeability of HSP nanocomposite hydrogels were evaluated. Then, the relationship between nanocomposite hydrogel and histological/antimicrobial properties was systematically analyzed. It was found that, the introduction of sericin increased internal pore size, leading to obvious transition from honeycomb to layered structure. Furthermore, as mass ratio of sericin/(sericin+NIPAm) is 20%, the wound healing area treated with nanocomposite hydrogels at 6th day reached up to 83%, 3 times of gauze, and almost recovered at 13th day. Especially, antibacterial mechanism can be thought to be the results that the macromolecular sericin embedded in the nanocomposite hydrogel adsorbed bacteria by charge interaction and micromolecular sericin dissociating out from nanocomposite hydrogels can be adsorbed onto bacteria. Copyright © 2017 Elsevier B.V. All rights reserved.
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DOE Office of Scientific and Technical Information (OSTI.GOV)
Knepper, S.M.
1985-01-01
Norepinephrine-(NE) and calcium ionophore A23187-stimulated phosphoinositide (PIn) metabolism in rat brain slices was studied under varying calcium conditions. Tissue was labelled with /sup 3/H-myo-inositol and /sup 3/H-inositol phosphates (IPn), products of PIn metabolism were measured. In the absence of media calcium the response to NE was decreased while that to A23187 was little affected A23187 can release calcium from intracellular stores. Basal and stimulated accumulation of /sup 3/H-IPn was reversibly antagonized with EGTA by addition of calcium. Using calcium buffers, approximately 10/sup -7/ M free calcium was required to support hydrolysis. Free intracellular calcium is maintained at approximately this level.more » Thus calcium is required for PIn hydrolysis but appears to play a permissive role, basal levels being sufficient to support metabolism. Conformationally-defined (rigid) and -restricted (semi-rigid) analogs of the most stable conformations of amphetamine, antiperiplanar (exo) and gauche (endo), were utilized to probe the conformational requirements of vesicular NE transport. Analogs tested were 2-aminotetralin (2AT), 3-methyltetrahydroisoquinoline, anti- and syn-9-aminobenzobicyclo(2.2.1)heptene, and endo and exo conformers of 2-aminobenzobicyclo(2.2.1)heptene and 2-aminobenzobicyclo(2.2.2)octene.« less
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Comparison of comet 81P/Wild 2 dust with interplanetary dust from comets.
Ishii, Hope A; Bradley, John P; Dai, Zu Rong; Chi, Miaofang; Kearsley, Anton T; Burchell, Mark J; Browning, Nigel D; Molster, Frank
2008-01-25
The Stardust mission returned the first sample of a known outer solar system body, comet 81P/Wild 2, to Earth. The sample was expected to resemble chondritic porous interplanetary dust particles because many, and possibly all, such particles are derived from comets. Here, we report that the most abundant and most recognizable silicate materials in chondritic porous interplanetary dust particles appear to be absent from the returned sample, indicating that indigenous outer nebula material is probably rare in 81P/Wild 2. Instead, the sample resembles chondritic meteorites from the asteroid belt, composed mostly of inner solar nebula materials. This surprising finding emphasizes the petrogenetic continuum between comets and asteroids and elevates the astrophysical importance of stratospheric chondritic porous interplanetary dust particles as a precious source of the most cosmically primitive astromaterials.
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Interplanetary magnetic field effects on high latitude ionospheric convection
NASA Technical Reports Server (NTRS)
Heelis, R. A.
1985-01-01
Relations between the electric field and the electric current in the ionosphere can be established on the basis of a system of mathematical and physical equations provided by the equations of current continuity and Ohm's law. For this reason, much of the synthesis of electric field and plasma velocity data in the F-region is made with the aid of similar data sets derived from field-aligned current and horizontal current measurements. During the past decade, the development of a self-consistent picture of the distribution and behavior of these measurements has proceeded almost in parallel. The present paper is concerned with the picture as it applies to the electric field and plasma drift velocity and its dependence on the interplanetary magnetic field. Attention is given to the southward interplanetary magnetic field and the northward interplanetary magnetic field.
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Study of Travelling Interplanetary Phenomena Report
NASA Astrophysics Data System (ADS)
Dryer, Murray
1987-09-01
Scientific progress on the topic of energy, mass, and momentum transport from the Sun into the heliosphere is contingent upon interdisciplinary and international cooperative efforts on the part of many workers. Summarized here is a report of some highlights of research carried out during the SMY/SMA by the STIP (Study of Travelling Interplanetary Phenomena) Project that included solar and interplanetary scientists around the world. These highlights are concerned with coronal mass ejections from solar flares or erupting prominences (sometimes together); their large-scale consequences in interplanetary space (such as shocks and magnetic 'bubbles'); and energetic particles and their relationship to these large-scale structures. It is concluded that future progress is contingent upon similar international programs assisted by real-time (or near-real-time) warnings of solar activity by cooperating agencies along the lines experienced during the SMY/SMA.
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Autonomous interplanetary constellation design
NASA Astrophysics Data System (ADS)
Chow, Cornelius Channing, II
According to NASA's integrated space technology roadmaps, space-based infrastructures are envisioned as necessary ingredients to a sustained effort in continuing space exploration. Whether it be for extra-terrestrial habitats, roving/cargo vehicles, or space tourism, autonomous space networks will provide a vital communications lifeline for both future robotic and human missions alike. Projecting that the Moon will be a bustling hub of activity within a few decades, a near-term opportunity for in-situ infrastructure development is within reach. This dissertation addresses the anticipated need for in-space infrastructure by investigating a general design methodology for autonomous interplanetary constellations; to illustrate the theory, this manuscript presents results from an application to the Earth-Moon neighborhood. The constellation design methodology is formulated as an optimization problem, involving a trajectory design step followed by a spacecraft placement sequence. Modeling the dynamics as a restricted 3-body problem, the investigated design space consists of families of periodic orbits which play host to the constellations, punctuated by arrangements of spacecraft autonomously guided by a navigation strategy called LiAISON (Linked Autonomous Interplanetary Satellite Orbit Navigation). Instead of more traditional exhaustive search methods, a numerical continuation approach is implemented to map the admissible configuration space. In particular, Keller's pseudo-arclength technique is used to follow folding/bifurcating solution manifolds, which are otherwise inaccessible with other parameter continuation schemes. A succinct characterization of the underlying structure of the local, as well as global, extrema is thus achievable with little a priori intuition of the solution space. Furthermore, the proposed design methodology offers benefits in computation speed plus the ability to handle mildly stochastic systems. An application of the constellation design methodology to the restricted Earth-Moon system, reveals optimal pairwise configurations for various L1, L2, and L5 (halo, axial, and vertical) periodic orbit families. Navigation accuracies, ranging from O (10+/-1) meters in position space, are obtained for the optimal Earth-Moon constellations, given measurement noise on the order of 1 meter.
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Electron dropout echoes induced by interplanetary shock: A statistical study
NASA Astrophysics Data System (ADS)
Liu, Z. Y.; Zong, Q.-G.; Hao, Y. X.; Zhou, X.-Z.; Ma, X. H.; Liu, Y.
2017-08-01
"Electron dropout echo" as indicated by repeated moderate dropout and recovery signatures of the flux of energetic electron in the outer radiation belt region has been investigated systematically. The electron moderate dropout and its echoes are usually found for higher-energy (>300 keV) channel fluxes, whereas the flux enhancements are obvious for lower energy electrons simultaneously after the interplanetary shock arrives at the Earth's geosynchronous orbit. The electron dropout echo events are found to be usually associated with the interplanetary shocks arrival. The 104 dropout echo events have been found from 215 interplanetary shock events from 1998 to 2007 based on the Los Alamos National Laboratory satellite data. In analogy to substorm injections, these 104 events could be naturally divided into two categories: dispersionless (49 events) or dispersive (55 events) according to the energy dispersion of the initial dropout. It is found that locations of dispersionless events are distributed mainly in the duskside magnetosphere. Further, the obtained locations derived from dispersive events with the time-of-flight technique of the initial dropout regions are mainly located at the duskside as well. Statistical studies have shown that the effect of shock normal, interplanetary magnetic field Bz and solar wind dynamic pressure may be insignificant to these electron dropout events. We suggest that the ˜1 min electric field impulse induced by the interplanetary shock produces a more pronounced inward migration of electrons at the duskside, resulting in the observed duskside moderate dropout of electron flux and its consequent echoes.
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Delay and Disruption Tolerant Networking MACHETE Model
NASA Technical Reports Server (NTRS)
Segui, John S.; Jennings, Esther H.; Gao, Jay L.
2011-01-01
To verify satisfaction of communication requirements imposed by unique missions, as early as 2000, the Communications Networking Group at the Jet Propulsion Laboratory (JPL) saw the need for an environment to support interplanetary communication protocol design, validation, and characterization. JPL's Multi-mission Advanced Communications Hybrid Environment for Test and Evaluation (MACHETE), described in Simulator of Space Communication Networks (NPO-41373) NASA Tech Briefs, Vol. 29, No. 8 (August 2005), p. 44, combines various commercial, non-commercial, and in-house custom tools for simulation and performance analysis of space networks. The MACHETE environment supports orbital analysis, link budget analysis, communications network simulations, and hardware-in-the-loop testing. As NASA is expanding its Space Communications and Navigation (SCaN) capabilities to support planned and future missions, building infrastructure to maintain services and developing enabling technologies, an important and broader role is seen for MACHETE in design-phase evaluation of future SCaN architectures. To support evaluation of the developing Delay Tolerant Networking (DTN) field and its applicability for space networks, JPL developed MACHETE models for DTN Bundle Protocol (BP) and Licklider/Long-haul Transmission Protocol (LTP). DTN is an Internet Research Task Force (IRTF) architecture providing communication in and/or through highly stressed networking environments such as space exploration and battlefield networks. Stressed networking environments include those with intermittent (predictable and unknown) connectivity, large and/or variable delays, and high bit error rates. To provide its services over existing domain specific protocols, the DTN protocols reside at the application layer of the TCP/IP stack, forming a store-and-forward overlay network. The key capabilities of the Bundle Protocol include custody-based reliability, the ability to cope with intermittent connectivity, the ability to take advantage of scheduled and opportunistic connectivity, and late binding of names to addresses.
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A Statistical Study of Interplanetary Type II Bursts: STEREO Observations
NASA Astrophysics Data System (ADS)
Krupar, V.; Eastwood, J. P.; Magdalenic, J.; Gopalswamy, N.; Kruparova, O.; Szabo, A.
2017-12-01
Coronal mass ejections (CMEs) are the primary cause of the most severe and disruptive space weather events such as solar energetic particle (SEP) events and geomagnetic storms at Earth. Interplanetary type II bursts are generated via the plasma emission mechanism by energetic electrons accelerated at CME-driven shock waves and hence identify CMEs that potentially cause space weather impact. As CMEs propagate outward from the Sun, radio emissions are generated at progressively at lower frequencies corresponding to a decreasing ambient solar wind plasma density. We have performed a statistical study of 153 interplanetary type II bursts observed by the two STEREO spacecraft between March 2008 and August 2014. These events have been correlated with manually-identified CMEs contained in the Heliospheric Cataloguing, Analysis and Techniques Service (HELCATS) catalogue. Our results confirm that faster CMEs are more likely to produce interplanetary type II radio bursts. We have compared observed frequency drifts with white-light observations to estimate angular deviations of type II burst propagation directions from radial. We have found that interplanetary type II bursts preferably arise from CME flanks. Finally, we discuss a visibility of radio emissions in relation to the CME propagation direction.
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Testing Fundamental Gravity with Interplanetary Laser Ranging
NASA Astrophysics Data System (ADS)
Turyshev, S. G.; Shao, M.; Hahn, I.
2018-02-01
Very accurate range measurements with the Interplanetary Laser Ranging Terminal (ILRT) will push high-precision tests of astrophysics/gravitation into a new regime. It could be used for navigation and investigations in planetary/lunar science.
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First Solar Power Sail Demonstration by IKAROS
NASA Astrophysics Data System (ADS)
Mori, Osamu; Sawada, Hirotaka; Funase, Ryu; Morimoto, Mutsuko; Endo, Tatsuya; Yamamoto, Takayuki; Tsuda, Yuichi; Kawakatsu, Yasuhiro; Kawaguchi, Jun'ichiro; Miyazaki, Yasuyuki; Shirasawa, Yoji; Demonstration Team; Solar Sail Working Group, Ikaros
The Japan Aerospace Exploration Agency (JAXA) will make the world's first solar power sail craft demonstration of photon propulsion and thin film solar power generation during its interplanetary cruise by IKAROS (Interplanetary Kite-craft Accelerated by Radiation Of the Sun). The spacecraft deploys and spans a membrane of 20 meters in diameter taking the advantage of the spin centrifugal force. The spacecraft weighs approximately 310kg, launched together with the agency's Venus Climate Orbiter, AKATSUKI in May 2010. This will be the first actual solar sail flying an interplanetary voyage.
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Research in space physics at the University of Iowa
NASA Technical Reports Server (NTRS)
Vanallen, J. A.
1979-01-01
Current investigations relating to energetic particles and the electric, magnetic, and electromagnetic fields associated with the earth, the sun, the moon, the planets, comets, and the interplanetary medium are reported. Primary emphasis is on observational work using a wide diversity of intruments on satellites of the earth and the moon and on planetary and interplanetary spacecraft, and on phenomenological analysis and interpretation. Secondary emphasis is given to closely related observational work by ground based radio-astronomical and optical techniques, and to theoretical problems in plasma physics as relevant to solar, planetary, and interplanetary phenomena.
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The emergence of different polarity photospheric flux as the cause of CMEs and interplanetary shocks
NASA Technical Reports Server (NTRS)
Bravo, S.
1995-01-01
Here we discuss the effect that the emergence of flux with a polarity opposed to that previously established in a certain photospheric region. can have on the magnetic structure of the solar atmosphere. We show that such a flux emergence may lead to the ejection of coronal material into the interplanetary medium (a CME) and also to a rapid change in the velocity of the solar wind from the region, which may eventually lead to the formation of an interplanetary shock.
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NASA Astrophysics Data System (ADS)
Singh, Y. P.; Badruddin
2007-02-01
Interplanetary manifestations of coronal mass ejections (CMEs) with specific plasma and field properties, called ``interplanetary magnetic clouds,'' have been observed in the heliosphere since the mid-1960s. Depending on their associated features, a set of observed magnetic clouds identified at 1 AU were grouped in four different classes using data over 4 decades: (1) interplanetary magnetic clouds moving with the ambient solar wind (MC structure), (2) magnetic clouds moving faster than the ambient solar wind and forming a shock/sheath structure of compressed plasma and field ahead of it (SMC structure), (3) magnetic clouds ``pushed'' by the high-speed streams from behind, forming an interaction region between the two (MIH structure), and (4) shock-associated magnetic clouds followed by high-speed streams (SMH structure). This classification into different groups led us to study the role, effect, and the relative importance of (1) closed field magnetic cloud structure with low field variance, (2) interplanetary shock and magnetically turbulent sheath region, (3) interaction region with large field variance, and (4) the high-speed solar wind stream coming from the open field regions, in modulating the galactic cosmic rays (GCRs). MC structures are responsible for transient decrease with fast recovery. SMC structures are responsible for fast decrease and slow recovery, MIH structures produce depression with slow decrease and slow recovery, and SMH structures are responsible for fast decrease with very slow recovery. Simultaneous variations of GCR intensity, solar plasma velocity, interplanetary magnetic field strength, and its variance led us to study the relative effectiveness of different structures as well as interplanetary plasma/field parameters. Possible role of the magnetic field, its topology, field turbulence, and the high-speed streams in influencing the amplitude and time profile of resulting decreases in GCR intensity have also been discussed.
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Nanodust released in interplanetary collisions
NASA Astrophysics Data System (ADS)
Lai, H. R.; Russell, C. T.
2018-07-01
The lifecycle of near-Earth objects (NEOs) involves a collisional cascade that produces ever smaller debris ending with nanoscale particles which are removed from the solar system by radiation pressure and electromagnetic effects. It has been proposed that the nanodust clouds released in collisions perturb the background interplanetary magnetic field and create the interplanetary field enhancements (IFEs). Assuming that this IFE formation scenario is actually operating, we calculate the interplanetary collision rate, estimate the total debris mass carried by nanodust, and compare the collision rate with the IFE rate. We find that to release the same amount of nanodust, the collision rate is comparable to the observed IFE rate. Besides quantitatively testing the association between the collisions evolving large objects and giant solar wind structures, such a study can be extended to ranges of smaller scales and to investigate the source of moderate and small solar wind perturbations.
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NASA Technical Reports Server (NTRS)
Bame, S. J.; Asbridge, J. R.; Feldman, W. C.; Gosling, J. T.; Zwickl, R. D.
1981-01-01
In near time coincidence with the arrival of helium enriched plasma driving the shock wave disturbance of November 12-13, 1978, strong bi-directional streaming of solar wind electrons greater than about 80 eV was observed with Los Alamos instrumentation on ISEE 3. The streaming persisted for many hours simultaneously parallel and anti-parallel to the interplanetary magnetic field which was directed roughly perpendicular to the sun-satellite line. This example of bidirectional streaming cannot be explained by field line connection to the earth's bow shock or the outward propagating interplanetary shock which passed ISEE 3 approximately 16 hours earlier. The event is explained if the local interplanetary field was a part of a magnetic bottle rooted at the sun or a disconnected loop propagating outward.
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Muon and neutron observations in connection with the corotating interaction regions
NASA Astrophysics Data System (ADS)
da Silva, M. R.; Dal Lago, A.; Echer, E.; de Lucas, A.; Gonzalez, W. D.; Schuch, N. J.; Munakata, K.; Vieira, L. E. A.; Guarnieri, F. L.
Ground cosmic ray observations are used for studying several kinds of interplanetary structures. The cosmic ray data has different responses to each kind of interplanetary structure. This article has as objective to study cosmic ray muon and neutron signatures due to the passage of corotating interaction region (CIR) in the interplanetary medium, and identify the signatures in the cosmic ray data due to these events. The cosmic ray muon data used in this work are recorded by the multidirectional muon detector installed at INPE’s Observatório Espacial do Sul OES/CRSPE/INPE-MCT, in São Martinho da Serra, RS (Brazil) and the neutron data was recorded by the neutron monitor installed in Newark (USA). The CIR events were selected in the period from 2001 to 2004. CIRs clearly affect cosmic ray density in the interplanetary medium in the Earth’s vicinity, where the magnetic field plays an important role.
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"Driverless" Shocks in the Interplanetary Medium
NASA Technical Reports Server (NTRS)
Gopalswamy, N.; Kaiser, M. L.; Lara, A.
1999-01-01
Many interplanetary shocks have been detected without an obvious driver behind them. These shocks have been thought to be either blast waves from solar flares or shocks due to sudden increase in solar wind speed caused by interactions between large scale open and closed field lines of the Sun. We investigated this problem using a set of interplanetary shock detected {\\it in situ} by the Wind space craft and tracing their solar origins using low frequency radio data obtained by the Wind/WAVES experiment. For each of these "driverless shocks" we could find a unique coronal mass ejections (CME) event observed by the SOHO (Solar and Heliospheric Observatory) coronagraphs. We also found that these CMEs were ejected at large angles from the Sun-Earth line. It appears that the "driverless shocks" are actually driver shocks, but the drivers were not intercepted by the spacecraft. We conclude that the interplanetary shocks are much more extended than the driving CMEs.
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GCR Modulation by Small-Scale Features in the Interplanetary Medium
NASA Astrophysics Data System (ADS)
Jordan, A. P.; Spence, H. E.; Blake, J. B.; Mulligan, T. L.; Shaul, D. N.; Galametz, M.
2007-12-01
In an effort to uncover the properties of structures in the interplanetary medium (IPM) that modulate galactic cosmic rays (GCR) on short time-scales (from hours to days), we study periods of differing conditions in the IPM. We analyze GCR variations from spacecraft both inside and outside the magnetosphere, using the High Sensitivity Telescope (HIST) on Polar and the Spectrometer for INTEGRAL (SPI). We seek causal correlations between the observed GCR modulations and structures in the solar wind plasma and interplanetary magnetic field, as measured concurrently with ACE and/or Wind. Our analysis spans time-/size-scale variations ranging from classic Forbush decreases (Fds), to substructure embedded within Fds, to much smaller amplitude and shorter duration variations observed during comparatively benign interplanetary conditions. We compare and contrast the conditions leading to the range of different GCR responses to modulating structures in the IPM.
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NASA Technical Reports Server (NTRS)
Pinter, S.; Dryer, M.
1985-01-01
The relationship between the thermal energy released from 29 solar flares and the propagation features of their associated interplanetary shock waves that were detected at 1 AU is investigated. The 29 interplanetary shock waves were identified unambiguously and their tracking from each solar flare was deduced by tracking their associated interplanetary type-II radio emission. The thermal energy released in the solar flares was estimated from the time-intensity profiles of 1-8 A soft X-ray bursts from each flare. A good relationship is found between the flares' thermal energy with the IP shock-waves' transient velocity and arrival time at the earth - that is, the largest flare energy released is associated with the faster shock waves. Finally, a possible scenario of formation of a shock wave during the early phase of the flare and its propagation features is discussed.
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Direct Measurements of Interplanetary Dust Particles in the Vicinity of Earth
NASA Technical Reports Server (NTRS)
McCracken, C. W.; Alexander, W. M.; Dubin, M.
1961-01-01
The direct measurements made by the Explorer VIII satellite provide the first sound basis for analyzing all available direct measurements of the distribution of interplanetary dust particles. The model average distribution curve established by such an analysis departs significantly from that predicted by the (uncertain) extrapolation of results from meteor observations. A consequence of this difference is that the daily accretion of interplanetary particulate matter by the earth is now considered to be mainly dust particles of the direct measurements range of particle size. Almost all the available direct measurements obtained with microphone systems on rockets, satellites, and spacecraft fit directly on the distribution curve defined by Explorer VIII data. The lack of reliable datum points departing significantly from the model average distribution curve means that available direct measurements show no discernible evidence of an appreciable geocentric concentration of interplanetary dust particles.
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XX International Workshop on Condensed Matter Theories
1998-01-01
Rojo5, M.A. Solis6 and A.A. Valladares4 1 Institute de Fisica Teorica-UNESP, 01405 Säo Paulo, BRAZIL and Departamento de Fisica , Universidade...Estadual de Londrina Londrina, PR, BRAZIL 2Departament de Fisica , Universität de les Hies Balears 07071 Palma de Mallorca, SPAIN department of Physics...SUNY, Buffalo, NY 14260-1500, USA 4Instituto de Investigaciones en Materiales, UN AM 04510 Mexico DF, MEXICO 5PESTIC, Secretaria Academica, IPN
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NASA Technical Reports Server (NTRS)
Schaire, Scott H.; Altunc, Serhat; Bussey, George; Shaw, Harry; Horne, Bill; Schier, Jim
2015-01-01
There has been a historical trend to increase capability and drive down the Size, Weight and Power (SWAP) of satellites and that trend continues today. Small satellites, including systems conforming to the CubeSat specification, because of their low launch and development costs, are enabling new concepts and capabilities for science investigations across multiple fields of interest to NASA. NASA scientists and engineers across many of NASAs Mission Directorates and Centers are developing exciting CubeSat concepts and welcome potential partnerships for CubeSat endeavors. From a communications and tracking point of view, small satellites including CubeSats are a challenge to coordinate because of existing small spacecraft constraints, such as limited SWAP and attitude control, low power, and the potential for high numbers of operational spacecraft. The NASA Space Communications and Navigation (SCaN) Programs Near Earth Network (NEN), Deep Space Network (DSN) and the Space Network (SN) are customer driven organizations that provide comprehensive communications services for space assets including data transport between a missions orbiting satellite and its Mission Operations Center (MOC). The NASA NEN consists of multiple ground antennas. The SN consists of a constellation of geosynchronous (Earth orbiting) relay satellites, named the Tracking and Data Relay Satellite System (TDRSS). The DSN currently makes available 13 antennas at its three tracking stations located around the world for interplanetary communication. The presentation will analyze how well these space communication networks are positioned to support the emerging small satellite and CubeSat market. Recognizing the potential support, the presentation will review the basic capabilities of the NEN, DSN and SN in the context of small satellites and will present information about NEN, DSN and SN-compatible flight radios and antenna development activities at the Goddard Space Flight Center (GSFC) and across industry. The presentation will review concepts on how the SN multiple access capability could help locate CubeSats and provide a low-latency early warning system. The presentation will also present how the DSN is evolving to maximize use of its assets for interplanetary CubeSats. The critical spectrum-related topics of available and appropriate frequency bands, licensing, and coordination will be reviewed. Other key considerations, such as standardization of radio frequency interfaces and flight and ground communications hardware systems, will be addressed as such standardization may reduce the amount of time and cost required to obtain frequency authorization and perform compatibility and end-to-end testing. Examples of standardization that exist today are the NASA NEN, DSN and SN systems which have published users guides and defined frequency bands for high data rate communication, as well as conformance to CCSDS standards. The workshop session will also seek input from the workshop participants to better understand the needs of small satellite systems and to identify key development activities and operational approaches necessary to enhance communication and navigation support using NASA's NEN, DSN and SN.
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Imaging Interplanetary CMEs at Radio Frequency From Solar Polar Orbit
NASA Astrophysics Data System (ADS)
Wu, Ji; Sun, Weiying; Zheng, Jianhua; Zhang, Cheng; Wang, Chi; Wang, C. B.; Wang, S.
Coronal mass ejections (CMEs) are violent discharges of plasma and magnetic fields from the Sun's corona. They have come to be recognized as the major driver of physical conditions in the Sun-Earth system. Consequently, the detection of CMEs is important for un-derstanding and ultimately predicting space weather conditions. The Solar Polar Orbit Radio Telescope (SPORT) is a proposed mission to observe the propagation of interplanetary CMEs from solar polar orbit. The main payload (radio telescope) on board SPORT will be an in-terferometric imaging radiometer working at the meter wavelength band, which will follow the propagation of interplanetary CMEs from a distance of a few solar radii to near 1 AU from solar polar orbit. The SPORT spacecraft will also be equipped with a set of optical and in situ measurement instruments such as a EUV solar telescope, a solar wind plasma experiment, a solar wind ion composition instrument, an energetic particle detector, a wave detector, a mag-netometer and an interplanetary radio burst tracker. In this paper, we first describe the current shortage of interplanetary CME observations. Next, the scientific motivation and objectives of SPORT are introduced. We discuss the basic specifications of the main radio telescope of SPORT with reference to the radio emission mechanisms and the radio frequency band to be observed. Finally, we discuss the key technologies of the SPORT mission, including the con-ceptual design of the main telescope, the image retrieval algorithm and the solar polar orbit injection. Other payloads and their respective observation objectives are also briefly discussed. Key words: Interplanetary CMEs; Interferometric imaging; Solar polar orbit; Radiometer.
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NASA Technical Reports Server (NTRS)
Stuart, J. R.
1984-01-01
The evolution of NASA's planetary navigation techniques is traced, and radiometric and optical data types are described. Doppler navigation; the Deep Space Network; differenced two-way range techniques; differential very long base interferometry; and optical navigation are treated. The Doppler system enables a spacecraft in cruise at high absolute declination to be located within a total angular uncertainty of 1/4 microrad. The two-station range measurement provides a 1 microrad backup at low declinations. Optical data locate the spacecraft relative to the target to an angular accuracy of 5 microrad. Earth-based radio navigation and its less accurate but target-relative counterpart, optical navigation, thus form complementary measurement sources, which provide a powerful sensory system to produce high-precision orbit estimates.
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Auroras observations of the MAIN in Apatity during 2014/15 winter season
NASA Astrophysics Data System (ADS)
Guineva, V.; Despirak, I.; Kozelov, B.
2017-08-01
In this work we review substorms, originated during the 2014/2015 winter season. Observations of the Multiscale Aurora Imaging Network (MAIN) in Apatity have been used. Solar wind and interplanetary magnetic field parameters were estimated by the 1-min sampled OMNI data base from CDAWeb (http://cdaweb.gsfc.nasa.gov/cdaweb/ istp_public/). Auroral disturbances were verified by the 10-s sampled data of IMAGE magnetometers and by data of the all-sky camera at Apatity. Subject of the review were the peculiarities in the development of substorms occurred during different geomagnetic conditions. The behavior of the substorms developed in non-storm time and during different phases of geomagnetic storms was discussed.
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2013-11-01
radomes6 to magnet casings for thermonuclear fusion reactors7,8 and support structures for interplanetary space probes.9 These properties...because the conversion is relatively easy to quantify via methods such as FT‐IR spectroscopy,17 investiga‐ tions of structure ‐property...the high‐temperature resistance and mechanical stiffness associated with aromatic content, which limits their poten‐ tial for high
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Systems analysis for ground-based optical navigation
NASA Technical Reports Server (NTRS)
Null, G. W.; Owen, W. M., Jr.; Synnott, S. P.
1992-01-01
Deep-space telecommunications systems will eventually operate at visible or near-infrared regions to provide increased information return from interplanetary spacecraft. This would require an onboard laser transponder in place of (or in addition to) the usual microwave transponder, as well as a network of ground-based and/or space-based optical observing stations. This article examines the expected navigation systems to meet these requirements. Special emphasis is given to optical astrometric (angular) measurements of stars, solar system target bodies, and (when available) laser-bearing spacecraft, since these observations can potentially provide the locations of both spacecraft and target bodies. The role of astrometry in the navigation system and the development options for astrometric observing systems are also discussed.
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Operating CFDP in the Interplanetary Internet
NASA Technical Reports Server (NTRS)
Burleigh, S.
2002-01-01
This paper examines the design elements of CCSDS File Delivery Protocol and Interplanetary Internet technologies that will simplify their integration and discusses the resulting new capabilities, such as efficient transmission of large files via multiple relay satellites operating in parallel.
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Interplanetary Trajectories, Encke Method (ITEM)
NASA Technical Reports Server (NTRS)
Whitlock, F. H.; Wolfe, H.; Lefton, L.; Levine, N.
1972-01-01
Modified program has been developed using improved variation of Encke method which avoids accumulation of round-off errors and avoids numerical ambiguities arising from near-circular orbits of low inclination. Variety of interplanetary trajectory problems can be computed with maximum accuracy and efficiency.
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Search Coil vs. Fluxgate Magnetometer Measurements at Interplanetary Shocks
NASA Technical Reports Server (NTRS)
Wilson, L.B., III
2012-01-01
We present magnetic field observations at interplanetary shocks comparing two different sample rates showing significantly different results. Fluxgate magnetometer measurements show relatively laminar supercritical shock transitions at roughly 11 samples/s. Search coil magnetometer measurements at 1875 samples/s, however, show large amplitude (dB/B as large as 2) fluctuations that are not resolved by the fluxgate magnetometer. We show that these fluctuations, identified as whistler mode waves, would produce a significant perturbation to the shock transition region changing the interpretation from laminar to turbulent. Thus, previous observations of supercritical interplanetary shocks classified as laminar may have been under sampled.
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Mars Science Laboratory Interplanetary Navigation Performance
NASA Technical Reports Server (NTRS)
Martin-Mur, Tomas J.; Kruizinga, Gerhard; Wong, Mau
2013-01-01
The Mars Science Laboratory spacecraft, carrying the Curiosity rover to Mars, hit the top of the Martian atmosphere just 200 meters from where it had been predicted more than six days earlier, and 2.6 million kilometers away. This un-expected level of accuracy was achieved by a combination of factors including: spacecraft performance, tracking data processing, dynamical modeling choices, and navigation filter setup. This paper will describe our best understanding of what were the factors that contributed to this excellent interplanetary trajectory prediction performance. The accurate interplanetary navigation contributed to the very precise landing performance, and to the overall success of the mission.
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Geometry of the diffusive propagation region in the August 14, 1982 solar electron event
NASA Technical Reports Server (NTRS)
Evenson, P. A.
1985-01-01
On August 14, 1982, relativistic electrons arrived promptly after an impulsive gamma ray flare, indicating that very little scattering was taking place in interplanetary space. By ignoring anisotropy data the time profile of the event is well described by interplanetary diffusion except for the derived particle injection time. This discrepancy provides independent evidence that the particles are diffusing in a volume close to the Sun rather than in interplanetary space. The flux at maximum method of determining the number of particles produced is still a good approximation when appropriately applied.
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NASA Technical Reports Server (NTRS)
Bravo, S.
1995-01-01
Coronal holes are the sources of the solar wind and, according to recent YOKOH observations, may undergo rapid changes which are associated with manifestations of explosive solar activity. Rapid changes in a hole's structure will produce rapid changes in the characteristics of the wind emerging from it and, in the particular c se of a sudden increase in wind velocity, this may lead to the formation of an interplanetary shock. We discuss the characteristics of shocks formed in such a way and compare them with interplanetary observations.
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1986-09-01
AD-R173 822 MWD SIMULATION OF THE INTERPLANETARY ENVIRONMENT IN THE 1/1 ECLIPTIC PLRNE DU (U) AIR FORCE GEOPHYSICS LAS HANSCOM AFB MA M DRYER ET AL...RESOLUTION TEST CHART M4rtqOAI RIM) Of STANDARMS 96I-A AFGL-TR-86-0189 M Simulation of the Interplanetary Environment in the Ecliptic Plane During the 3-9...CLASSIFICATION OF THIS PAGE Cant of Block 11: in the Ecliptic Plane During the 3-9 February 1986 Solar and Geomagnetic Activity Cant of Block 19 (ABSTRACT
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NASA Technical Reports Server (NTRS)
Spangelo, Sara; Dalle, Derek; Longmier, Benjamin
2015-01-01
This paper investigates the feasibility of Earth-transfer and interplanetary mission architectures for miniaturized spacecraft using emerging small solar electric propulsion technologies. Emerging small SEP thrusters offer significant advantages relative to existing technologies and will enable U-class systems to perform trajectory maneuvers with significant Delta V requirements. The approach in this paper is unique because it integrates trajectory design with vehicle sizing and accounts for the system and operational constraints of small U-class missions. The modeling framework includes integrated propulsion, orbit, energy, and external environment dynamics and systems-level power, energy, mass, and volume constraints. The trajectory simulation environment models orbit boosts in Earth orbit and flyby and capture trajectories to interplanetary destinations. A family of small spacecraft mission architectures are studied, including altitude and inclination transfers in Earth orbit and trajectories that escape Earth orbit and travel to interplanetary destinations such as Mercury, Venus, and Mars. Results are presented visually to show the trade-offs between competing performance objectives such as maximizing available mass and volume for payloads and minimizing transfer time. The results demonstrate the feasibility of using small spacecraft to perform significant Earth and interplanetary orbit transfers in less than one year with reasonable U-class mass, power, volume, and mission durations.
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3-D model of ICME in the interplanetary medium
NASA Astrophysics Data System (ADS)
Borgazzi, A.; Lara, A.; Niembro, T.
2011-12-01
We developed a method that describes with simply geometry the coordinates of intersection between the leading edge of an ICME and the position of an arbitrary satellite. When a fast CME is ejected from the Sun to the interplanetary space in most of the cases drives a shock. As the CME moves in the corona and later in the interplanetary space more material is stacking in the front and edges of the ejecta. In a first approximation, it is possible to assume the shape of these structures, the CME and the stacked material as a cone of revolution, (the ice-cream model [Schwenn et al., (2005)]). The interface may change due to the interaction of the structure and the non-shocked material in front of the ICME but the original shape of a cone of revolution is preserved. We assume, in a three dimensional geometry, an ice-cream cone shape for the ICME and apply an analytical model for its transport in the interplanetary medium. The goal of the present method is to give the time and the intersection coordinates between the leading edge of the ICME and any satellite that may be in the path of the ICME. With this information we can modelate the travel of the ICME in the interplanetary space using STEREO data.
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NASA Technical Reports Server (NTRS)
Clements, E. B.; Carlton, A. K.; Joyce, C. J.; Schwadron, N. A.; Spence, H. E.; Sun, X.; Cahoy, K.
2016-01-01
Space weather is a major concern for radiation-sensitive space systems, particularly for interplanetary missions, which operate outside of the protection of Earth's magnetic field. We examine and quantify the effects of space weather on silicon avalanche photodiodes (SiAPDs), which are used for interplanetary laser altimeters and communications systems and can be sensitive to even low levels of radiation (less than 50 cGy). While ground-based radiation testing has been performed on avalanche photodiode (APDs) for space missions, in-space measurements of SiAPD response to interplanetary space weather have not been previously reported. We compare noise data from the Lunar Reconnaissance Orbiter (LRO) Lunar Orbiter Laser Altimeter (LOLA) SiAPDs with radiation measurements from the onboard Cosmic Ray Telescope for the Effects of Radiation (CRaTER) instrument. We did not find any evidence to support radiation as the cause of changes in detector threshold voltage during radiation storms, both for transient detector noise and long-term average detector noise, suggesting that the approximately 1.3 cm thick shielding (a combination of titanium and beryllium) of the LOLA detectors is sufficient for SiAPDs on interplanetary missions with radiation environments similar to what the LRO experienced (559 cGy of radiation over 4 years).
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NASA Technical Reports Server (NTRS)
Flynn, G. J.
1993-01-01
Calculations by Anders and Chyba et al. have recently revived interest in the suggestion that organic compounds important to the development of life were delivered to the primitive surface of the Earth by comets, asteroids or the interplanetary dust derived from these two sources. Anders has shown that the major post-accretion contribution of extraterrestrial organic matter to the surface of the Earth is from interplanetary dust. Since Mars is a much more favorable site for the gentle deceleration of interplanetary dust particles than is Earth, model calculations show that biologically important organic compounds are likely to have been delivered to the early surface of Mars by the interplanetary dust in an order-of-magnitude higher surface density than onto the early Earth. Using the method described by Flynn and McKay, the size frequency distribution, and the atmospheric entry velocity distribution of IDP's at Mars were calculated. The entry velocity distribution, coupled with the atmospheric entry heating model developed by Whipple and extended by Fraundorf was used to calculate the fraction of the particles in each mass decade which survives atmospheric entry without melting (i.e., those not heated above 1600K). The incident mass and surviving mass in each mass decade are shown for both Earth and Mars.
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NASA Astrophysics Data System (ADS)
Morgan, J. S.; Macquart, J. P.; Ekers, R.; Bisi, M. M.; Jackson, B. V.; Tokumaru, M.; Manoharan, P. K.; Chhetri, R.
2016-12-01
Interplanetary scintillation (IPS) is a phenomenon which can be used to probe both the heliospheric plasma and the structure of compact astrophysical radio sources. It is a vital tool for near-real-time monitoring of space weather. Previous IPS studies have generally relied on single concentrated collecting areas (either phased arrays or dishes). The Murchison Widefield Array (MWA) by contrast is a new-generation instrument consisting of a 128-element interferometer with an extremely wide field of view, and outstanding instantaneous imaging capability. This enables IPS studies of 1000 sources simultaneously, increasing the number of daily measurements that can be made by a factor of two or more. Here we report on progress from an ongoing IPS survey with the MWA where observations are made simultaneously at 80MHz and 150MHz. Dual-frequency observations allow solar wind velocities to be determined even with a single station, more accurately than from the analyses of a single-frequency IPS spectrum alone. Furthermore, the different refractive indices at different wavelengths leads to a lag in the cross correlation of the two frequency bands. This allows the bulk density of the outer solar corona to be probed along multiple lines of sight. We will discuss recent results and how they might be integrated into international Space Weather Prediction efforts such as the Worldwide IPS Stations (WIPSS) Network.
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NASA Astrophysics Data System (ADS)
Bisi, Mario M.; Fallows, Richard A.; Sobey, Charlotte; Eftekhari, Tarraneh; Jensen, Elizabeth A.; Jackson, Bernard V.; Yu, Hsiu-Shan; Hick, P. Paul; Odstrcil, Dusan; Tokumaru, Munetoshi; Oyuki Chang, M. T.
2016-04-01
Space weather - analogous to terrestrial weather (describing the changing pressure, temperature, wind, and humidity conditions on Earth) - is essentially a description of the changes in velocity, density, magnetic field, high-energy particles, and radiation in the near-Earth space environment including the effects of such on the Earth. Space weather can be considered to have two main strands: (i) scientific research, and (ii) applications. The former is self-explanatory, but the latter covers operational aspects including forecasting. Understanding and forecasting space weather near the Earth is of critical importance to protecting our modern-day reliance on satellites, global-communications and navigation networks, high-altitude air travel (radiation concerns particularly on polar routes), long-distance power/oil/gas lines and piping, and for any future human exploration of space to list but a few. This includes both military and commercial considerations. Two ground-based radio-observing techniques that can add to and lead our understanding and forecasting of heliospheric space weather are those of interplanetary scintillation (IPS) and heliospheric Faraday rotation (FR). We present our latest progress using these two radio heliospheric-imaging remote-sensing techniques including the use of three-dimensional (3-D) modelling and reconstruction techniques using other, additional data as input to support and better-interpret individual case-study results.
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Perspectives of intellectual processing of large volumes of astronomical data using neural networks
NASA Astrophysics Data System (ADS)
Gorbunov, A. A.; Isaev, E. A.; Samodurov, V. A.
2018-01-01
In the process of astronomical observations vast amounts of data are collected. BSA (Big Scanning Antenna) LPI used in the study of impulse phenomena, daily logs 87.5 GB of data (32 TB per year). This data has important implications for both short-and long-term monitoring of various classes of radio sources (including radio transients of different nature), monitoring the Earth’s ionosphere, the interplanetary and the interstellar plasma, the search and monitoring of different classes of radio sources. In the framework of the studies discovered 83096 individual pulse events (in the interval of the study highlighted July 2012 - October 2013), which may correspond to pulsars, twinkling springs, and a rapid radio transients. Detected impulse events are supposed to be used to filter subsequent observations. The study suggests approach, using the creation of the multilayered artificial neural network, which processes the input raw data and after processing, by the hidden layer, the output layer produces a class of impulsive phenomena.
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Data at Risk and Research Libraries
NASA Astrophysics Data System (ADS)
Choudhury, S.
2017-12-01
Research libraries have recently engaged in data rescue events amidst growing concerns about access to federal data sets. While these efforts are well intentioned, libraries run the risk of ignoring a long established history of activities and accomplishments by other communities focused on data at risk, many of which are represented at forums such as AGU. Under the auspices of the Data Conservancy, the Sheridan Libraries at Johns Hopkins University hosted an event in July 2017 that convened members of various communities including ESIP, RDA, Data Rescue Boulder, Association of Research Libraries, the Fedora repository platform, the Open Science Framework and the Interplanetary File System or IPFS (via the Data Together Network). This group identified a potential role for research libraries to partner with existing players in the data at risk community by focusing on a distributed preservation network as part of a coordinated collection development program. This session will offer an opportunity to hear about this potential role for research libraries and to provide feedback about its viability and utility.
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NASA Astrophysics Data System (ADS)
Curkendall, D. W.; Border, J. S.
2013-05-01
Doppler and range data alone supported navigation for the earliest missions into deep space. Though extremely precise in line-of-sight coordinates, the navigation system built on these data had a weakness for determining the spacecraft declination component. To address this, the Deep Space Network (DSN) developed the capability for very long baseline interferometry measurements beginning in the late 1970s. Both the implementation of the interferometric system and the importance of such measurements to flight projects have evolved significantly over the past three decades. Innovations introduced through research and development programs have led to continuous improvements in performance. Today's system provides data approaching one-nanoradian accuracy with reliability of 98 percent. This article provides an overview of the development and use of interferometric tracking techniques in the DSN starting with the Viking era and continuing with a description of the current system and its planned use to support interplanetary cruise navigation of the Mars Science Laboratory spacecraft.
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JAXA-NASA Interoperability Demonstration for Application of DTN Under Simulated Rain Attenuation
NASA Technical Reports Server (NTRS)
Suzuki, Kiyoshisa; Inagawa, Shinichi; Lippincott, Jeff; Cecil, Andrew J.
2014-01-01
As is well known, K-band or higher band communications in space link segment often experience intermittent disruptions caused by heavy rainfall. In view of keeping data integrity and establishing autonomous operations under such situation, it is important to consider introducing a tolerance mechanism such as Delay/Disruption Tolerant Networking (DTN). The Consultative Committee for Space Data Systems (CCSDS) is studying DTN as part of the standardization activities for space data systems. As a contribution to CCSDS and a feasibility study for future utilization of DTN, Japan Aerospace Exploration Agency (JAXA) and National Aeronautics and Space Administration (NASA) conducted an interoperability demonstration for confirming its tolerance mechanism and capability of automatic operation using Data Relay Test Satellite (DRTS) space link and its ground terminals. Both parties used the Interplanetary Overlay Network (ION) open source software, including the Bundle Protocol, the Licklider Transmission Protocol, and Contact Graph Routing. This paper introduces the contents of the interoperability demonstration and its results.
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Moon based global field airglow: For Artemis or any common Lunar Lander
NASA Astrophysics Data System (ADS)
Kozlowski, R. W. H.; Sprague, A. L.; Sandel, B. R.; Hunten, D. M.; Broadfoot, A. L.
1994-06-01
An inexpensive, small mass, airglow experiment consisting of a suite of airglow detectors is planned for one or more lunar landers. Solid state detectors measuring light through narrow band filters or concave gratings can integrate emissions from lunar atmospheric constituents and store the information for relay to earth when convenient. The proposed instrument is a simplified version of the Shuttle-borne Arizona Imager-Spectrograph. These zenith and near horizon viewing detectors may allow us to monitor fluctuations in atomic species of oxygen, calcium, sodium, potassium, argon, and neon and OH, if present. This choice of observations would monitor outgassing from the interior (Ar), meteoritic dust flux (Na, K) solar wind sputtering (O, Ca), and outgassing from the surface (implanted Ne, Na, K). A global network could be inexpensively deployed aboard landers carrying a variety of other selenographic instrumentation. Powered by solar cells such a field network will return data applicable to a wide variety of interplanetary medium and solar-lunar interaction problems.
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LaRC-RP41: A Tough, High-Performance Composite Matrix
NASA Technical Reports Server (NTRS)
Pater, Ruth H.; Johnston, Norman J.; Smith, Ricky E.; Snoha, John J.; Gautreaux, Carol R.; Reddy, Rakasi M.
1991-01-01
New polymer exhibits increased toughness and resistance to microcracking. Cross-linking PMR-15 and linear LaRC-TPI combined to provide sequential semi-2-IPN designated as LaRC-RP41. Synthesized from PMR-15 imide prepolymer undergoing cross-linking in immediate presence of LaRC-TPI polyamic acid, also undergoing simultaneous imidization and linear chain extension. Potentially high-temperature matrix resin, adhesive, and molding resin. Applications include automobiles, electronics, aircraft, and aerospace structures.
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NASA Astrophysics Data System (ADS)
Budianto, Emil; Fauzia, Maghfira
2018-04-01
The administration of amoxicillin trihydrate in Helicobacter pylori infection is not effective enough because the conventional preparations used have a short retention time in the stomach. To overcome this problem, amoxicillin trihydrate was encapsulated into the floating drug delivery matrix-matrix. In this study, the full-ipn acetaldehyde crosslinked hydrogel (N-vinyl caprolactam) was synthesized with a 10% CaCO3 pore forming agent and then encapsulated on amoxicillin trihydrate and studied the mechanism of drug dissolution with its kinetic kinetics approach. The K-PNVCL Hydrogel produces optimal properties which are then loaded with amoxicillin trihydrate in situ and post loading. In this research, we have got the percentage of swelling, floating time, the efficiency of in situ and post loading 873%; 3.15 minutes; 99.8% and 99.4%. The dissolution test was performed on amoxicillin trihydrate which had been encapsulated K-PNVCL hydrogel in vitro at pH 1.2 resulting in 94.5% for in situ loading and 98.5% for post loading. Results of the kinetics of drug release for post loading and in situ loading methods tend to follow the Higuchi model kinetics. The drug release mechanism occurs by Fickian diffusion. Proof of drug release mechanism from K-PNVCL hydrogel matrix is further done by Scanning Electron Microscope (SEM) instrument.
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NASA Astrophysics Data System (ADS)
Fithawati, Garnis; Budianto, Emil
2018-04-01
Common treatment for Helicobacter pylori by repeated oral consumption of amoxicillin trihydrate is not effective. Amoxicillin trihydrate has a very short residence time in stomach which leads into its ineffectiveness. Residence time of amoxicillin trihydrate can be improved by encapsulating amoxicillin trihydrate into a floating drug delivery system. In this study, amoxicillin trihydrate is encapsulated into hydrogel semi-IPN chitosan methyl cellulose matrix as a floating drug delivery system and then treated with 20% KHCO3 as pore forming agent. Drug loading process used are in-situ loading and post loading. In-situ loading process has higher efficiency percentage and dissolution percentage than post loading process. In-situ loading process resulted 100% efficiency with 92,70% dissolution percentage. Post loading process resulted 98,7% efficiency with 90,42% dissolution percentage. Mechanism of drug dissolution study by kinetics approach showed both in-situ loading process and post loading process are diffusion and degradation process (n=0,4913) and (n=0,4602) respectively. These results are supported by characterization data from optical microscope and scanning electron microscopy (SEM). Data from optical microscope showed both loading process resulted in coarser hydrogel surface. Characterization using SEM showed elongated pores in both loading process after dissolution test.
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DOE Office of Scientific and Technical Information (OSTI.GOV)
Onchi, T.; Zushi, H.; Hanada, K.
2015-08-15
Heat flux and plasma flow in the scrape-off layer (SOL) are examined for the inboard poloidal field null (IPN) configuration of the spherical tokamak QUEST. In the plasma current (I{sub p}) ramp-up phase, high heat flux (>1 MW/m{sup 2}) and supersonic flow (Mach number M > 1) are found to be present simultaneously in the far-SOL. The heat flux is generated by energetic electrons excursed from the last closed flux surface. Supersonic flows in the poloidal and toroidal directions are correlated with each other. In the quasi-steady state, sawtooth-like oscillation of I{sub p} at 20 Hz is observed. Heat flux and subsonic plasma flowmore » in the far-SOL are modified corresponding to the I{sub p}-oscillation. The heat flow caused by motion of energetic electrons and the bulk-particle transport to the far-SOL is enhanced during the low-I{sub p} phase. Modification of plasma flow in the far SOL occurs earlier than the I{sub p} crash. The M–I{sub p} curve has a limit-cycle characteristic with sawtooth-like oscillation. Such a core–SOL relationship indicates that the far-SOL flow plays an important role in sustaining the oscillation of I{sub p} in the IPN configuration.« less
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NASA Astrophysics Data System (ADS)
Xiong, Ming; Davies, Jackie A.; Li, Bo; Yang, Liping; Liu, Ying D.; Xia, Lidong; Harrison, Richard A.; Keiji, Hayashi; Li, Huichao
2017-07-01
Interplanetary corotating interaction regions (CIRs) can be remotely imaged in white light (WL), as demonstrated by the Solar Mass Ejection Imager (SMEI) on board the Coriolis spacecraft and Heliospheric Imagers (HIs) on board the twin Solar TErrestrial RElations Observatory (STEREO) spacecraft. The interplanetary WL intensity, due to Thomson scattering of incident sunlight by free electrons, is jointly determined by the 3D distribution of electron number density and line-of-sight (LOS) weighting factors of the Thomson-scattering geometry. The 2D radiance patterns of CIRs in WL sky maps look very different from different 3D viewpoints. Because of the in-ecliptic locations of both the STEREO and Coriolis spacecraft, the longitudinal dimension of interplanetary CIRs has, up to now, always been integrated in WL imagery. To synthesize the WL radiance patterns of CIRs from an out-of-ecliptic (OOE) vantage point, we perform forward magnetohydrodynamic modeling of the 3D inner heliosphere during Carrington Rotation CR1967 at solar maximum. The mixing effects associated with viewing 3D CIRs are significantly minimized from an OOE viewpoint. Our forward modeling results demonstrate that OOE WL imaging from a latitude greater than 60° can (1) enable the garden-hose spiral morphology of CIRs to be readily resolved, (2) enable multiple coexisting CIRs to be differentiated, and (3) enable the continuous tracing of any interplanetary CIR back toward its coronal source. In particular, an OOE view in WL can reveal where nascent CIRs are formed in the extended corona and how these CIRs develop in interplanetary space. Therefore, a panoramic view from a suite of wide-field WL imagers in a solar polar orbit would be invaluable in unambiguously resolving the large-scale longitudinal structure of CIRs in the 3D inner heliosphere.
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Real-time Upstream Monitoring System: Using ACE Data to Predict the Arrival of Interplanetary Shocks
NASA Astrophysics Data System (ADS)
Donegan, M. M.; Wagstaff, K. L.; Ho, G. C.; Vandegriff, J.
2003-12-01
We have developed an algorithm to predict Earth arrival times for interplanetary (IP) shock events originating at the Sun. Our predictions are generated from real-time data collected by the Electron, Proton, and Alpha Monitor (EPAM) instrument on NASA's Advanced Composition Explorer (ACE) spacecraft. The high intensities of energetic ions that occur prior to and during an IP shock pose a radiation hazard to astronauts as well as to electronics in Earth orbit. The potential to predict such events is based on characteristic signatures in the Energetic Storm Particle (ESP) event ion intensities which are often associated with IP shocks. We have previously reported on the development and implementation of an algorithm to forecast the arrival of ESP events. Historical ion data from ACE/EPAM was used to train an artificial neural network which uses the signature of an approaching event to predict the time remaining until the shock arrives. Tests on the trained network have been encouraging, with an average error of 9.4 hours for predictions made 24 hours in advance, and an reduced average error of 4.9 hours when the shock is 12 hours away. The prediction engine has been integrated into a web-based system that uses real-time ACE/EPAM data provided by the NOAA Space Environment Center (http://sd-www.jhuapl.edu/UPOS/RISP/ index.html.) This system continually processes the latest ACE data, reports whether or not there is an impending shock, and predicts the time remaining until the shock arrival. Our predictions are updated every five minutes and provide significant lead-time, thereby supplying critical information that can be used by mission planners, satellite operations controllers, and scientists. We have continued to refine the prediction capabilities of this system; in addition to forecasting arrival times for shocks, we now provide confidence estimates for those predictions.
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NASA Astrophysics Data System (ADS)
Bisi, M. M.; Gonzalez-Esparza, A.; Jackson, B. V.; Aguilar-Rodriguez, E.; Tokumaru, M.; Chashei, I. V.; Tyul'bashev, S. A.; Manoharan, P. K.; Fallows, R. A.; Chang, O.; Mejia-Ambriz, J. C.; Yu, H. S.; Fujiki, K.; Shishov, V.
2016-12-01
The phenomenon of space weather - analogous to terrestrial weather which describes the changing low-altitude atmospheric conditions on Earth - is essentially a description of the changes in the plasma environment at and near the Earth. Some key parameters for space-weather purposes driving space weather at the Earth include velocity, density, magnetic field, high-energy particles, and radiation coming into and within the near-Earth space environment. Interplanetary scintillation (IPS) can be used to provide a global measure of velocity and density as well as indications of changes in the plasma and magnetic-field rotations along each observational line of sight. If the observations are formally inverted into a three-dimensional (3-D) tomographic reconstruction (such as using the University of California, San Diego - UCSD - kinematic model and reconstruction technique), then source-surface magnetic fields can also be propagated out to the Earth (and beyond) as well as in-situ data also being incorporated into the reconstruction. Currently, this has been done using IPS data only from the Institute for Space-Earth Environmental (ISEE) and has been scientifically since the 1990s, and in a forecast mode since around 2000. There is now a defined IPS Common Data Format (IPSCDFv1.0) which is being implemented by the majority of the IPS community (this also feeds into the tomography). The Worldwide IPS Stations (WIPSS) Network aims to bring together, using IPSCDFv1.0, the worldwide real-time capable IPS observatories with well-developed and tested analyses techniques being unified across all single-site systems (such as MEXART, Pushchino, and Ooty) and cross-calibrated to the multi-site ISEE system (as well as learning from the scientific-based systems such as EISCAT, LOFAR, and the MWA), into the UCSD 3-D tomography to improve the accuracy, spatial and temporal data coverage, and both the spatial and temporal resolution for improved space-weather science and forecast capabilities.
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NASA Astrophysics Data System (ADS)
Bisi, Mario Mark; Americo Gonzalez-Esparza, J.; Jackson, Bernard; Aguilar-Rodriguez, Ernesto; Tokumaru, Munetoshi; Chashei, Igor; Tyul'bashev, Sergey; Manoharan, Periasamy; Fallows, Richard; Chang, Oyuki; Yu, Hsiu-Shan; Fujiki, Ken'ichi; Shishov, Vladimir; Barnes, David
2017-04-01
The phenomenon of space weather - analogous to terrestrial weather which describes the changing low-altitude atmospheric conditions on Earth - is essentially a description of the changes in the plasma environment at and near the Earth. Some key parameters for space-weather purposes driving space weather at the Earth include velocity, density, magnetic field, high-energy particles, and radiation coming into and within the near-Earth space environment. Interplanetary scintillation (IPS) can be used to provide a global measure of velocity and density as well as indications of changes in the plasma and magnetic-field rotations along each observational line of sight. If the observations are formally inverted into a three-dimensional (3-D) tomographic reconstruction (such as using the University of California, San Diego - UCSD - kinematic model and reconstruction technique), then source-surface magnetic fields can also be propagated out to the Earth (and beyond) as well as in-situ data also being incorporated into the reconstruction. Currently, this has been done using IPS data only from the Institute for Space-Earth Environmental (ISEE) and has been scientifically since the 1990s, and in a forecast mode since around 2000. There is now a defined (and updated) IPS Common Data Format (IPSCDFv1.1) which is being implemented by the majority of the IPS community (this also feeds into the UCSD tomography). The Worldwide IPS Stations (WIPSS) Network aims to bring together, using IPSCDFv1.1, the worldwide real-time capable IPS observatories with well-developed and tested analyses techniques being unified across all single-site systems (such as MEXART, Pushchino, and Ooty) and cross-calibrated to the multi-site ISEE system (as well as learning from the scientific-based systems such as EISCAT, LOFAR, and the MWA), into the UCSD 3-D tomography to improve the accuracy, spatial and temporal data coverage, and both the spatial and temporal resolution for improved space-weather science and forecast capabilities.
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NASA Technical Reports Server (NTRS)
Alves, L. R.; Da Silva, L. A.; Souza, V. M.; Sibeck, D. G.; Jauer, P. R.; Vieira, L. E. A.; Walsh, B. M.; Silveira, M. V. D.; Marchezi, J. P.; Rockenbach, M.;
2016-01-01
Magnetopause shadowing and wave-particle interactions are recognized as the two primary mechanisms for losses of electrons from the outer radiation belt. We investigate these mechanisms, sing satellite observations both in interplanetary space and within the magnetosphere and particle drift modeling. Two interplanetary shocks sheaths impinged upon the magnetopause causing a relativistic electron flux dropout. The magnetic cloud (C) and interplanetary structure sunward of the MC had primarily northward magnetic field, perhaps leading to a concomitant lack of substorm activity and a 10 day long quiescent period. The arrival of two shocks caused an unusual electron flux dropout. Test-particle simulations have shown 2 to 5 MeV energy, equatorially mirroring electrons with initial values of L 5.5can be lost to the magnetosheath via magnetopause shadowing alone. For electron losses at lower L-shells, coherent chorus wave-driven pitch angle scattering and ULF wave-driven radial transport have been shownto be viable mechanisms.
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Interplanetary magnetic field control of the Mars bow shock: Evidence for Venuslike interaction
DOE Office of Scientific and Technical Information (OSTI.GOV)
Zhang, T.L.; Schwingenschuh, K.; Lichtenegger, H.
1991-07-01
The Mars bow shock location and shape have been determined by examining the PHOBOS spacecraft magnetometer data. Observations show that the position of the terminator bow shock varies with interplanetary magnetic field orientation in the same way as at Venus. The shock is farthest from Mars in the direction of the interplanetary electric field, consistent with the idea that mass loading plays an important role in the solar wind interaction with Mars. The authors also find that the shock cross section at the terminator plane is asymmetric and is controlled by the interplanetary magnetic field as expected from the asymmetricmore » propagation velocity of the fast magnetosonic wave. Comparing with earlier mission data, they show that the Mars shock location varies with solar activity. The shock is farther from Mars during solar maximum. Thus the solar wind interaction with Mars appears to be Venuslike, with a magnetic moment too small to affect significantly the solar wind interaction.« less
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The interplanetary exchange of photosynthesis.
Cockell, Charles S
2008-02-01
Panspermia, the transfer of organisms from one planet to another, either through interplanetary or interstellar space, remains speculation. However, its potential can be experimentally tested. Conceptually, it is island biogeography on an interplanetary or interstellar scale. Of special interest is the possibility of the transfer of oxygenic photosynthesis between one planet and another, as it can initiate large scale biospheric productivity. Photosynthetic organisms, which must live near the surface of rocks, can be shown experimentally to be subject to destruction during atmospheric transit. Many of them grow as vegetative cells, which are shown experimentally to be susceptible to destruction by shock during impact ejection, although the effectiveness of this dispersal filter can be shown to be mitigated by the characteristics of the cells and their local environment. Collectively these, and other, experiments reveal the particular barriers to the cross-inoculation of photosynthesis. If oxygen biosignatures are eventually found in the atmospheres of extrasolar planets, understanding the potential for the interplanetary exchange of photosynthesis will aid in their interpretation.
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Interplanetary Electric Propulsion Uranus Mission Trades Supporting the Decadal Survey
NASA Technical Reports Server (NTRS)
Dankanich, John W.; McAdams, James
2011-01-01
The Decadal Survey Committee was tasked to develop a comprehensive science and mission strategy for planetary science that updates and extends the National Academies Space Studies Board s current solar system exploration decadal survey. A Uranus orbiter mission has been evaluated as a part of this 2013-2022 Planetary Science Decadal Survey. A comprehensive Uranus orbiter mission design was completed, including a broad search of interplanetary electric propulsion transfer options. The scope of interplanetary trades was limited to electric propulsion concepts, both solar and radioisotope powered. Solar electric propulsion offers significant payloads to Uranus. Inserted mass into the initial science orbit due is highly sensitive to transfer time due to arrival velocities. The recommended baseline trajectory is a 13 year transfer with an Atlas 551, a 1+1 NEXT stage with 15 kW of power using an EEJU trajectory and a 1,000km EGA flyby altitude constraint. This baseline delivers over 2,000kg into the initial science orbit. Interplanetary trajectory trades and sensitivity analyses are presented herein.
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PROPAGATION AND EVOLUTION OF THE JUNE 1st 2008 CME IN THE INTERPLANETARY MEDIUM
NASA Astrophysics Data System (ADS)
Nieves-Chinchilla, T.; Lamb, D. A.; Davila, J. M.; Vinas, A. F.; Moestl, C.; Hidalgo, M. A.; Farrugia, C. J.; Malandraki, O.; Dresing, N.; Gómez-Herrero, R.
2009-12-01
In this work we present a study of the coronal mass ejection (CME) of June 1st of 2008 in the interplanetary medium. This event has been extensively studied by others because of its favorable geometry and the possible consequences of its peculiar initiation for space weather forecasting. We show an analysis of the evolution of the CME in the interplanetary medium in order to shed some light on the propagation mechanism of the ICME. We have determined the typical shock associated characteristics of the ICME in order to understand the propagation properties. Using two different non force-free models of the magnetic cloud allows us to incorporate expansion of the cloud. We use in-situ measurements from STEREO B/IMPACT to characterize the ICME. In addition, we use images from STEREO A/SECCHI-HI to analyze the propagation and visual evolution of the associated flux rope in the interplanetary medium. We compare and contrast these observations with the results of the analytical models.
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The causes of recurrent geomagnetic storms
NASA Technical Reports Server (NTRS)
Burlaga, L. F.; Lepping, R. P.
1976-01-01
The causes of recurrent geomagnetic activity were studied by analyzing interplanetary magnetic field and plasma data from earth-orbiting spacecraft in the interval from November 1973 to February 1974. This interval included the start of two long sequences of geomagnetic activity and two corresponding corotating interplanetary streams. In general, the geomagnetic activity was related to an electric field which was due to two factors: (1) the ordered, mesoscale pattern of the stream itself, and (2) random, smaller-scale fluctuations in the southward component of the interplanetary magnetic field Bz. The geomagnetic activity in each recurrent sequence consisted of two successive stages. The first stage was usually the most intense, and it occurred during the passage of the interaction region at the front of a stream. These large amplitudes of Bz were primarily produced in the interplanetary medium by compression of ambient fluctuations as the stream steepened in transit to 1 A.U. The second stage of geomagnetic activity immediately following the first was associated with the highest speeds in the stream.
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The search for refractory interplanetary dust particles from preindustrial aged Antarctic ice
NASA Technical Reports Server (NTRS)
Zolensky, Michael E.; Webb, Susan J.; Thomas, Kathie
1988-01-01
In a study of refractory interplanetary dust particles, preindustrial-aged Antarctic ice samples have been collected, melted, and filtered to separate the particle load. Particles containing a significant amount of aluminum, titanium, and/or calcium were singled out for detailed SEM and STEM characterization. The majority of these particles are shown to be volcanic tephra from nearby volcanic centers. Six spherical aggregates were encountered that consist of submicron-sized grains of rutile within polycrystalline cristobalite. These particles are probably of terrestrial volcanic origin, but have not been previously reported from any environment. One aggregate particle containing fassaite and hibonite is described as a probable interplanetary dust particle. The constituent grain sizes of this particle vary from 0.1 to 0.3 microns, making it significantly more fine-grained than meteoritic calcium-aluminum-rich inclusions. This particle is mineralogically and morphologically similar to recently reported refractory interplanetary dust particles collected from the stratosphere, and dissimilar to the products of modern spacecraft debris.
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Microscale Bioadhesive Hydrogel Arrays for Cell Engineering Applications.
Patel, Ravi Ghanshyam; Purwada, Alberto; Cerchietti, Leandro; Inghirami, Giorgio; Melnick, Ari; Gaharwar, Akhilesh K; Singh, Ankur
2014-09-01
Bioengineered hydrogels have been explored in cell and tissue engineering applications to support cell growth and modulate its behavior. A rationally designed scaffold should allow for encapsulated cells to survive, adhere, proliferate, remodel the niche, and can be used for controlled delivery of biomolecules. Here we report a microarray of composite bioadhesive microgels with modular dimensions, tunable mechanical properties and bulk modified adhesive biomolecule composition. Composite bioadhesive microgels of maleimide functionalized polyethylene glycol (PEG-MAL) with interpenetrating network (IPN) of gelatin ionically cross-linked with silicate nanoparticles were engineered by integrating microfabrication with Michael-type addition chemistry and ionic gelation. By encapsulating clinically relevant anchorage-dependent cervical cancer cells and suspension leukemia cells as cell culture models in these composite microgels, we demonstrate enhanced cell spreading, survival, and metabolic activity compared to control gels. The composite bioadhesive hydrogels represent a platform that could be used to study independent effect of stiffness and adhesive ligand density on cell survival and function. We envision that such microarrays of cell adhesive microenvironments, which do not require harsh chemical and UV crosslinking conditions, will provide a more efficacious cell culture platform that can be used to study cell behavior and survival, function as building blocks to fabricate 3D tissue structures, cell delivery systems, and high throughput drug screening devices.
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Microscale Bioadhesive Hydrogel Arrays for Cell Engineering Applications
PATEL, RAVI GHANSHYAM; PURWADA, ALBERTO; CERCHIETTI, LEANDRO; INGHIRAMI, GIORGIO; MELNICK, ARI; GAHARWAR, AKHILESH K.; SINGH, ANKUR
2014-01-01
Bioengineered hydrogels have been explored in cell and tissue engineering applications to support cell growth and modulate its behavior. A rationally designed scaffold should allow for encapsulated cells to survive, adhere, proliferate, remodel the niche, and can be used for controlled delivery of biomolecules. Here we report a microarray of composite bioadhesive microgels with modular dimensions, tunable mechanical properties and bulk modified adhesive biomolecule composition. Composite bioadhesive microgels of maleimide functionalized polyethylene glycol (PEG-MAL) with interpenetrating network (IPN) of gelatin ionically cross-linked with silicate nanoparticles were engineered by integrating microfabrication with Michael-type addition chemistry and ionic gelation. By encapsulating clinically relevant anchorage-dependent cervical cancer cells and suspension leukemia cells as cell culture models in these composite microgels, we demonstrate enhanced cell spreading, survival, and metabolic activity compared to control gels. The composite bioadhesive hydrogels represent a platform that could be used to study independent effect of stiffness and adhesive ligand density on cell survival and function. We envision that such microarrays of cell adhesive microenvironments, which do not require harsh chemical and UV crosslinking conditions, will provide a more efficacious cell culture platform that can be used to study cell behavior and survival, function as building blocks to fabricate 3D tissue structures, cell delivery systems, and high throughput drug screening devices. PMID:25328548
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New Directions in Space Operations Services in Support of Interplanetary Exploration
NASA Technical Reports Server (NTRS)
Bradford, Robert N.
2005-01-01
To gain access to the necessary operational processes and data in support of NASA's Lunar/Mars Exploration Initiative, new services, adequate levels of computing cycles and access to myriad forms of data must be provided to onboard spacecraft and ground based personnel/systems (earth, lunar and Martian) to enable interplanetary exploration by humans. These systems, cycles and access to vast amounts of development, test and operational data will be required to provide a new level of services not currently available to existing spacecraft, on board crews and other operational personnel. Although current voice, video and data systems in support of current space based operations has been adequate, new highly reliable and autonomous processes and services will be necessary for future space exploration activities. These services will range from the more mundane voice in LEO to voice in interplanetary travel which because of the high latencies will require new voice processes and standards. New services, like component failure predictions based on data mining of significant quantities of data, located at disparate locations, will be required. 3D or holographic representation of onboard components, systems or family members will greatly improve maintenance, operations and service restoration not to mention crew morale. Current operational systems and standards, like the Internet Protocol, will not able to provide the level of service required end to end from an end point on the Martian surface like a scientific instrument to a researcher at a university. Ground operations whether earth, lunar or Martian and in flight operations to the moon and especially to Mars will require significant autonomy that will require access to highly reliable processing capabilities, data storage based on network storage technologies. Significant processing cycles will be needed onboard but could be borrowed from other locations either ground based or onboard other spacecraft. Reliability will be a key factor with onboard and distributed backup processing an absolutely necessary requirement. Current cluster processing/Grid technologies may provide the basis for providing these services. An overview of existing services, future services that will be required and the technologies and standards required to be developed will be presented. The purpose of this paper will be to initiate a technological roadmap, albeit at a high level, of current voice, video, data and network technologies and standards (which show promise for adaptation or evolution) to what technologies and standards need to be redefined, adjusted or areas where new ones require development. The roadmap should begin the differentiation between non manned and manned processes/services where applicable. The paper will be based in part on the activities of the CCSDS Monitor and Control working group which is beginning the process of standardization of the these processes. Another element of the paper will be based on an analysis of current technologies supporting space flight processes and services at JSC, MSFC, GSFC and to a lesser extent at KSC. Work being accomplished in areas such as Grid computing, data mining and network storage at ARC, IBM and the University of Alabama at Huntsville will be researched and analyzed.
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Dependence of the High Latitude Middle Atmosphere Ionization on Structures in Interplanetary Space
NASA Technical Reports Server (NTRS)
Bremer, J.; Lauter, E. A.
1984-01-01
The precipitation of high energetic electrons during and after strong geomagnetic storms into heights below 100 km in middle and subauroral latitudes is markedly modulated by the structure of the interplanetary magnetic field (IMF). Under relative quiet conditions the D-region ionization caused by high energetic particle precipitation (energies greater than 20 to 50 keV) depends on changes of the interplanetary magnetic field and also on the velocity of the solar wind. To test this assumption, the influence of the IMF-sector boundary crossings on ionospheric absorption data of high and middle latitudes by the superposed-epoch method was investigated.
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NASA Technical Reports Server (NTRS)
Kumar, S.; Broadfoot, A. L.
1979-01-01
A detailed analysis is conducted which shows that signatures in the interplanetary Lyman-alpha emissions observed in three different data sets from Mariner 10 (corresponding to different locations of the spacecraft) provide firm evidence that the intensity departures are correlated with a decrease in solar wind flux with increasing latitude. It is suggested that observations of the interplanetary emission can be used to monitor average solar wind activity at high latitudes. The asymmetry in the solar radiation field as a source of observed departures in L-alpha data is considered and attention is given to the interstellar hydrogen and helium density.
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Interstellar chemistry recorded in organic matter from primitive meteorites.
Busemann, Henner; Young, Andrea F; Alexander, Conel M O'd; Hoppe, Peter; Mukhopadhyay, Sujoy; Nittler, Larry R
2006-05-05
Organic matter in extraterrestrial materials has isotopic anomalies in hydrogen and nitrogen that suggest an origin in the presolar molecular cloud or perhaps in the protoplanetary disk. Interplanetary dust particles are generally regarded as the most primitive solar system matter available, in part because until recently they exhibited the most extreme isotope anomalies. However, we show that hydrogen and nitrogen isotopic compositions in carbonaceous chondrite organic matter reach and even exceed those found in interplanetary dust particles. Hence, both meteorites (originating from the asteroid belt) and interplanetary dust particles (possibly from comets) preserve primitive organics that were a component of the original building blocks of the solar system.
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Global Optimization of Interplanetary Trajectories in the Presence of Realistic Mission Contraints
NASA Technical Reports Server (NTRS)
Hinckley, David, Jr.; Englander, Jacob; Hitt, Darren
2015-01-01
Interplanetary missions are often subject to difficult constraints, like solar phase angle upon arrival at the destination, velocity at arrival, and altitudes for flybys. Preliminary design of such missions is often conducted by solving the unconstrained problem and then filtering away solutions which do not naturally satisfy the constraints. However this can bias the search into non-advantageous regions of the solution space, so it can be better to conduct preliminary design with the full set of constraints imposed. In this work two stochastic global search methods are developed which are well suited to the constrained global interplanetary trajectory optimization problem.
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Optical spectroscopy of interplanetary dust collected in the earth's stratosphere
NASA Technical Reports Server (NTRS)
Fraundorf, P.; Patel, R. I.; Shirck, J.; Walker, R. M.; Freeman, J. J.
1980-01-01
Optical absorption spectra of interplanetary dust particles 2-30 microns in size collected in the atmosphere at an altitude of 20 km by inertial impactors mounted on NASA U-2 aircraft are reported. Fourier transform absorption spectroscopy of crushed samples of the particles reveals a broad feature in the region 1300-800 kaysers which has also been found in meteorite and cometary dust spectra, and a weak iron crystal field absorption band at approximately 9800 kaysers, as is observed in meteorites. Work is currently in progress to separate the various components of the interplanetary dust particles in order to evaluate separately their contributions to the absorption.
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The Radiation, Interplanetary Shocks, and Coronal Sources (RISCS) Toolset
NASA Technical Reports Server (NTRS)
Zank, G. P.; Spann, James F.
2014-01-01
The goal of this project is to serve the needs of space system designers and operators by developing an interplanetary radiation environment model within 10 AU:Radiation, Interplanetary Shocks, and Coronal Sources (RISCS) toolset: (1) The RISCS toolset will provide specific reference environments for space system designers and nowcasting and forecasting capabilities for space system operators; (2) We envision the RISCS toolset providing the spatial and temporal radiation environment external to the Earth's (and other planets') magnetosphere, as well as possessing the modularity to integrate separate applications (apps) that can map to specific magnetosphere locations and/or perform the subsequent radiation transport and dosimetry for a specific target.
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NASA Astrophysics Data System (ADS)
Zong, Qiugang
Strong interplanetary shocks interaction with the Earth's magnetosphere would have great impacts on the Earth's magnetosphere. Cluster and Double Star constellation provides an ex-cellent opportunity to study the inner magnetospheric response to a powerful interplanetary solar wind forcing. An interplanetary shock on Nov.7 2004 with the solar wind dynamic pres-sure ˜ 70 nPa (Maximum) induced a large bipolar electric field in the plasmasphere boundary layer as observed by Cluster fleet, the peak-to-peak ∆Ey is more than 60 mV/m. Energetic elec-trons in the outer radiation belt are accelerated almost simultaneously when the interplanetary shock impinges upon the Earth's magnetosphere. Energetic electron bursts are coincident with the induced large electric field, energetic electrons (30 to 500 keV) with 900 pitch angles are accelerated first whereas those electrons are decelerated when the shock-induced electric field turns to positive value. Both toroidal and poloidal mode waves are found to be important but interacting with energetic electron at a different L-shell and a different period. At the Cluster's position (L = 4.4,), poloidal is predominant wave mode whereas at the geosynchronous orbits (L = 6.6), the ULF waves observed by the GOES -10 and -12 satellites are mostly toroidal. For comparison, a rather weak interplanetary shock on Aug. 30, 2001 (dynamic pressure ˜ 2.7 nPa) is also investigated in this paper. It is found that interplanetary shocks or solar wind pressure pulses with even small dynamic pressure change would have non-ignorable role in the radiation belt dynamic. Further, in this paper, our results also reveal the excitation of ULF waves re-sponses on the passing interplanetary shock, especially the importance of difference ULF wave modes when interacting with the energetic electrons in the radiation belt. The damping of the shock induced ULF waves could be separated into two terms: one term corresponds to the generalized Landau damping, the damping rate is large and the damping is fast; the other term corresponds to the damping through ionosphere due to its finite electric conductivity, the damping rate of this item is small and the damping is slow. The fast damping rate at (˜ 10-3 ) is significant larger than the slow damping rate (˜ 10-4 ) suggesting a rapid ULF wave energy lost is via drift resonance with energetic electrons in the radiation belt.
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Observations of a Small Interplanetary Magnetic Flux Rope Opening by Interchange Reconnection
NASA Astrophysics Data System (ADS)
Wang, J. M.; Feng, H. Q.; Zhao, G. Q.
2018-01-01
Interchange reconnection, specifically magnetic reconnection between open magnetic fields and closed magnetic flux ropes, plays a major role in the heliospheric magnetic flux budget. It is generally accepted that closed magnetic field lines of interplanetary magnetic flux ropes (IMFRs) can gradually open through reconnection between one of its legs and other open field lines until no closed field lines are left to contribute flux to the heliosphere. In this paper, we report an IMFR associated with a magnetic reconnection exhaust, whereby its closed field lines were opening by a magnetic reconnection event near 1 au. The reconnection exhaust and the following IMFR were observed on 2002 February 2 by both the Wind and ACE spacecraft. Observations on counterstreaming suprathermal electrons revealed that most magnetic field lines of the IMFR were closed, especially those after the front boundary of the IMFR, with both ends connected to the Sun. The unidirectional suprathermal electron strahls before the exhaust manifested the magnetic field lines observed before the exhaust was open. These observations provide direct evidence that closed field lines of IMFRs can be opened by interchange reconnection in interplanetary space. This is the first report of the closed field lines of IMFRs being opened by interchange reconnection in interplanetary space. This type of interplanetary interchange reconnection may pose important implications for balancing the heliospheric flux budget.
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DOE Office of Scientific and Technical Information (OSTI.GOV)
Lhotka, Christoph; Bourdin, Philippe; Narita, Yasuhito, E-mail: christoph.lhotka@oeaw.ac.at, E-mail: philippe.bourdin@oeaw.ac.at, E-mail: yasuhito.narita@oeaw.ac.at
We investigate the combined effect of solar wind, Poynting–Robertson drag, and the frozen-in interplanetary magnetic field on the motion of charged dust grains in our solar system. For this reason, we derive a secular theory of motion by the means of an averaging method and validate it with numerical simulations of the unaveraged equations of motions. The theory predicts that the secular motion of charged particles is mainly affected by the z -component of the solar magnetic axis, or the normal component of the interplanetary magnetic field. The normal component of the interplanetary magnetic field leads to an increase ormore » decrease of semimajor axis depending on its functional form and sign of charge of the dust grain. It is generally accepted that the combined effects of solar wind and photon absorption and re-emmision (Poynting–Robertson drag) lead to a decrease in semimajor axis on secular timescales. On the contrary, we demonstrate that the interplanetary magnetic field may counteract these drag forces under certain circumstances. We derive a simple relation between the parameters of the magnetic field, the physical properties of the dust grain, as well as the shape and orientation of the orbital ellipse of the particle, which is a necessary conditions for the stabilization in semimajor axis.« less
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Applications of presently planned interplanetary missions to testing gravitational theories
NASA Technical Reports Server (NTRS)
Friedman, L. D.
1971-01-01
A summary of the probable interplanetary missions for the 1970's is presented, which may prove useful in testing the general theory of relativity. Mission characteristics are discussed, as well as instrumentation. This last includes a low-level accelerometer and S-/X-band transponders and antennas.
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A Bibliography of References in Natural Water Photochemistry
1984-12-01
Impacto ambiental do la derrama, del Pozo IXTOC-I sobre 91 zooplancton. I.P.N. Falk-Peterson, I.-B., Saethre, L. J. and LUnning, S., 1982. Toxic effects of...larvas, postlarvas, jueveniles y adultos do camaron y adultos do osti6n y pulpo por medio de biosensayos. Cientffica y Ticnica. Universidad de Sonora...spill: Flaking of surface mousse in the Gulf of Mexico . Nature 290: 235-238. Payne, J., 1984.t Physical/chemical weathering of petroleum in the marine
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Thin layer activation techniques at the U-120 cyclotron of Bucharest
NASA Astrophysics Data System (ADS)
Constantinescu, B.; Ivanov, E. A.; Pascovici, G.; Popa-Simil, L.; Racolta, P. M.
1994-05-01
The Thin Layer Activation (TLA) technique is a nuclear method especially used for different types of wear (or corrosion) investigations. Experimental results for selection criteria of nuclear reactions for various tribological studies, using the IPNE U-120 classical variable energy Cyclotron are presented. Measuring methods for the main types of wear phenomena and home made instrumentations dedicated for TLA industrial applications are also reported. Some typical TLA tribological applications, a nuclear scanning method to obtain wear profile of piston-rings are presented as well.
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Sequential ranging integration times in the presence of CW interference in the ranging channel
NASA Technical Reports Server (NTRS)
Mathur, Ashok; Nguyen, Tien
1986-01-01
The Deep Space Network (DSN), managed by the Jet Propulsion Laboratory for NASA, is used primarily for communication with interplanetary spacecraft. The high sensitivity required to achieve planetary communications makes the DSN very susceptible to radio-frequency interference (RFI). In this paper, an analytical model is presented of the performance degradation of the DSN sequential ranging subsystem in the presence of downlink CW interference in the ranging channel. A trade-off between the ranging component integration times and the ranging signal-to-noise ratio to achieve a desired level of range measurement accuracy and the probability of error in the code components is also presented. Numerical results presented illustrate the required trade-offs under various interference conditions.
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Large-scale solar magnetic fields and H-alpha patterns
NASA Technical Reports Server (NTRS)
Mcintosh, P. S.
1972-01-01
Coronal and interplanetary magnetic fields computed from measurements of large-scale photospheric magnetic fields suffer from interruptions in day-to-day observations and the limitation of using only measurements made near the solar central meridian. Procedures were devised for inferring the lines of polarity reversal from H-alpha solar patrol photographs that map the same large-scale features found on Mt. Wilson magnetograms. These features may be monitored without interruption by combining observations from the global network of observatories associated with NOAA's Space Environment Services Center. The patterns of inferred magnetic fields may be followed accurately as far as 60 deg from central meridian. Such patterns will be used to improve predictions of coronal features during the next solar eclipse.
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Detecting TLEs using a massive all-sky camera network
NASA Astrophysics Data System (ADS)
Garnung, M. B.; Celestin, S. J.
2017-12-01
Transient Luminous Events (TLEs) are large-scale optical events occurring in the upper-atmosphere from the top of thunderclouds up to the ionosphere. TLEs may have important effects in local, regional, and global scales, and many features of TLEs are not fully understood yet [e.g, Pasko, JGR, 115, A00E35, 2010]. Moreover, meteor events have been suggested to play a role in sprite initiation by producing ionospheric irregularities [e.g, Qin et al., Nat. Commun., 5, 3740, 2014]. The French Fireball Recovery and InterPlanetary Observation Network (FRIPON, https://www.fripon.org/?lang=en), is a national all-sky 30 fps camera network designed to continuously detect meteor events. We seek to make use of this network to observe TLEs over unprecedented space and time scales ( 1000×1000 km with continuous acquisition). To do so, we had to significantly modify FRIPON's triggering software Freeture (https://github.com/fripon/freeture) while leaving the meteor detection capability uncompromised. FRIPON has a great potential in the study of TLEs. Not only could it produce new results about spatial and time distributions of TLEs over a very large area, it could also be used to validate and complement observations from future space missions such as ASIM (ESA) and TARANIS (CNES). In this work, we present an original image processing algorithm that can detect sprites using all-sky cameras while strongly limiting the frequency of false positives and our ongoing work on sprite triangulation using the FRIPON network.
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Gelatin- and starch-based hydrogels. Part A: Hydrogel development, characterization and coating.
Van Nieuwenhove, Ine; Salamon, Achim; Peters, Kirsten; Graulus, Geert-Jan; Martins, José C; Frankel, Daniel; Kersemans, Ken; De Vos, Filip; Van Vlierberghe, Sandra; Dubruel, Peter
2016-11-05
The present work aims at constructing the ideal scaffold matrix of which the physico-chemical properties can be altered according to the targeted tissue regeneration application. Ideally, this scaffold should resemble the natural extracellular matrix (ECM) as close as possible both in terms of chemical composition and mechanical properties. Therefore, hydrogel films were developed consisting of methacrylamide-modified gelatin and starch-pentenoate building blocks because the ECM can be considered as a crosslinked hydrogel network consisting of both polysaccharides and structural, signaling and cell-adhesive proteins. For the gelatin hydrogels, three different substitution degrees were evaluated including 31%, 72% and 95%. A substitution degree of 32% was applied for the starch-pentenoate building block. Pure gelatin hydrogels films as well as interpenetrating networks with gelatin and starch were developed. Subsequently, these films were characterized using gel fraction and swelling experiments, high resolution-magic angle spinning (1)H NMR spectroscopy, rheology, infrared mapping and atomic force microscopy. The results indicate that both the mechanical properties and the swelling extent of the developed hydrogel films can be controlled by varying the chemical composition and the degree of substitution of the methacrylamide-modified gelatin applied. The storage moduli of the developed materials ranged between 14 and 63kPa. Phase separation was observed for the IPNs for which separated starch domains could be distinguished located in the surrounding gelatin matrix. Furthermore, we evaluated the affinity of aggrecan for gelatin by atomic force microscopy and radiolabeling experiments. We found that aggrecan can be applied as a bioactive coating for gelatin hydrogels by a straightforward physisorption procedure. Thus, we achieved distinct fine-tuning of the physico-chemical properties of these hydrogels which render them promising candidates for tissue engineering approaches. Copyright © 2016 Elsevier Ltd. All rights reserved.
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NASA Astrophysics Data System (ADS)
Ocaña, Francisco
2017-05-01
PhD Thesis defended the 5th June 2017. Universidad Complutense de Madrid.This dissertation undertakes the research of the interplanetary matter near the Earth using two different observational approaches.The first one is based on the detection of the sunlight reflected by the bodies. The detection and characterisation of these nearby population require networks of medium-sized telescopes to survey and track them. We design a robotic system (the TBT telescopes) for the European Space Agency as a prototype for a future network. The first unit is already installed in Spain and we present the results of the commissioning. Additionally we evaluate the expected performance of such an instrument using a simulation with a synthetic population. We consider that the system designed is a powerful instrument for nearby asteroid discovery and tracking. It is based on commercial components, and therefore ready for a scalable implementation in a global network.Meanwhile the bodies smaller than asteroids are observed using the atmosphere as a detector. When these particles collide with the atmospheric molecules they are heated, ablated, sublimated, and finally light is emitted by these hot vapours, what we call meteors. We conduct the investigation of these meteors to study the meteoroids. In particular we address two different topics: On one hand we explore the size/mass frequency distribution of meteoroids using flux determination when the collide into the atmosphere. We develop a method to determine this flux using video observations of meteors and analyse the properties of meteors as an optical proxy to meteoroids in order to maximise the detection. It yields three ground-based observational solutions that we transform into instrumental designs. First we design and develop a meteor all-sky detection station for Observatorio UCM and use the Draconids 2011 campaign as a showcase for the flux determination, with successful results. Then we investigate the observation of meteors with instruments in stratospheric balloons, overcoming troposphere handicaps like weather or extinction. On the other hand we design a filter set for narrow-band photometry for meteoroid characterisation, equivalent to low-R spectroscopy. We reproduce the classification of meteors using synthetic photometry over a spectra catalogue. We find the V-R colour to have a significant dependence to meteor speed and meteoroid composition, what implies a significant detection bias for unfiltered or broadband instruments.
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NASA Astrophysics Data System (ADS)
Ocaña, Francisco
2017-05-01
PhD Thesis defended the 5th June 2017. Universidad Complutense de Madrid.This dissertation undertakes the research of the interplanetary matter near the Earth using two different observational approaches.The first one is based on the detection of the sunlight reflected by the bodies. The detection and characterisation of these nearby population require networks of medium-sized telescopes to survey and track them. We design a robotic system (the TBT telescopes) for the European Space Agency as a prototype for a future network. The first unit is already installed in Spain and we present the results of the commissioning. Additionally we evaluate the expected performance of such an instrument using a simulation with a synthetic population. We consider that the system designed is a powerful instrument for nearby asteroid discovery and tracking. It is based on commercial components, and therefore ready for a scalable implementation in a global network.Meanwhile the bodies smaller than asteroids are observed using the atmosphere as a detector. When these particles collide with the atmospheric molecules they are heated, ablated, sublimated, and finally light is emitted by these hot vapours, what we call meteors. We conduct the investigation of these meteors to study the meteoroids. In particular we address two different topics: On one hand we explore the size/mass frequency distribution of meteoroids using flux determination when the collide into the atmosphere. We develop a method to determine this flux using video observations of meteors and analyse the properties of meteors as an optical proxy to meteoroids in order to maximise the detection. It yields three ground-based observational solutions that we transform into instrumental designs. First we design and develop a meteor all-sky detection station for Observatorio UCM and use the Draconids 2011 campaign as a showcase for the flux determination, with successful results. Then we investigate the observation of meteors with instruments in stratospheric balloons, overcoming troposphere handicaps like weather or extinction. On the other hand we design a filter set for narrow-band photometry for meteoroid characterisation, equivalent to low-R spectroscopy. We reproduce the classification of meteors using synthetic photometry over a spectra catalogue. We find the V-R colour to have a significant dependence to meteor speed and meteoroid composition, what implies a significant detection bias for unfiltered or broadband instruments.
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Remote Asynchronous Message Service Gateway
NASA Technical Reports Server (NTRS)
Wang, Shin-Ywan; Burleigh, Scott C.
2011-01-01
The Remote Asynchronous Message Service (RAMS) gateway is a special-purpose AMS application node that enables exchange of AMS messages between nodes residing in different AMS "continua," notionally in different geographical locations. JPL s implementation of RAMS gateway functionality is integrated with the ION (Interplanetary Overlay Network) implementation of the DTN (Delay-Tolerant Networking) bundle protocol, and with JPL s implementation of AMS itself. RAMS protocol data units are encapsulated in ION bundles and are forwarded to the neighboring RAMS gateways identified in the source gateway s AMS management information base. Each RAMS gateway has interfaces in two communication environments: the AMS message space it serves, and the RAMS network - the grid or tree of mutually aware RAMS gateways - that enables AMS messages produced in one message space to be forwarded to other message spaces of the same venture. Each gateway opens persistent, private RAMS network communication channels to the RAMS gateways of other message spaces for the same venture, in other continua. The interconnected RAMS gateways use these communication channels to forward message petition assertions and cancellations among themselves. Each RAMS gateway subscribes locally to all subjects that are of interest in any of the linked message spaces. On receiving its copy of a message on any of these subjects, the RAMS gateway node uses the RAMS network to forward the message to every other RAMS gateway whose message space contains at least one node that has subscribed to messages on that subject. On receiving a message via the RAMS network from some other RAMS gateway, the RAMS gateway node forwards the message to all subscribers in its own message space.
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Modeling of ion acceleration through drift and diffusion at interplanetary shocks
NASA Technical Reports Server (NTRS)
Decker, R. B.; Vlahos, L.
1986-01-01
A test particle simulation designed to model ion acceleration through drift and diffusion at interplanetary shocks is described. The technique consists of integrating along exact particle orbits in a system where the angle between the shock normal and mean upstream magnetic field, the level of magnetic fluctuations, and the energy of injected particles can assume a range of values. The technique makes it possible to study time-dependent shock acceleration under conditions not amenable to analytical techniques. To illustrate the capability of the numerical model, proton acceleration was considered under conditions appropriate for interplanetary shocks at 1 AU, including large-amplitude transverse magnetic fluctuations derived from power spectra of both ambient and shock-associated MHD waves.
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Upstream electron oscillations and ion overshoot at an interplanetary shock wave
NASA Technical Reports Server (NTRS)
Potter, D. W.; Parks, G. K.
1983-01-01
During the passage of a large interplanetary shock on Oct. 13, 1981, the ISEE-1 and -2 spacecraft were in the solar wind outside of the upstream region of the bow shock. The high time resolution data of the University of California particle instruments allow pinpointing the expected electron spike as occurring just before the magnetic ramp. In addition, two features that occur at this shock have not been observed before: electron oscillations associated with low frequency waves upstream of the shock and sharp 'overshoot' (about 1 sec) in the ion fluxes that occur right after the magnetic ramp. This interplanetary shock exhibits many of the same characteristics that are observed at the earth's bow shock.
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Radio Emmision during the interaction of two Interplanetary Coronal Mass Ejections
NASA Astrophysics Data System (ADS)
Lara, Alejandro; Niembro, Tatiana; González, Ricardo
2016-07-01
We show that some sporadic radio emission observed by the WIND/WAVES experiment in the decametric/kilometric bands are due to the interaction of two interplanetary Coronal Mass Ejections. We have performed hydrodynamic simulations of the evolution of two consecutive Coronal Mass ejections in the interplanetary medium. With these simulations it is possible to follow the density evolution of the merged structure, and therefore, compute the frequency limits of the possible plasma emission. We study four well documented ICME interaction events, and found radio emission at the time and frequencies predicted by the simulations. This emission may help to anticipate the complexity of the merged region before it reaches one AU.
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Infrared spectroscopy of interplanetary dust in the laboratory
NASA Technical Reports Server (NTRS)
Fraundorf, P.; Patel, R. I.; Freeman, J. J.
1981-01-01
A mount containing three crushed chondritic interplanetary dust particles (IDPs) collected in the earth's stratosphere and subjected to infrared spectroscopic measurements shows features near 1000 and 500/cm, suggesting crystalline pyroxene rather than crystalline olivine, amorphous olivine, or meteoritic clay minerals. Chondritic IDP structural diversity and atmospheric heating effects must be considered when comparing this spectrum with interplanetary and cometary dust astrophysical spectra. TEM and infrared observations of one member of the rare subset of IDPs resembling hydrated carbonaceous chondrite matrix material shows a close infrared spectrum resemblance between 4000 and 400/cm to the C2 meteorite Murchison. TEM observations suggest that this class of particles may be used as an atmospheric entry heating-process thermometer.
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NASA Technical Reports Server (NTRS)
Burlaga, L. F.; Ness, N. F.
1976-01-01
A literature review is presented of theoretical models of the interaction of the solar wind and interplanetary magnetic fields. Observations of interplanetary magnetic fields by the IMP and OSO spacecraft are discussed. The causes for cosmic ray variations (Forbush decreases) by the solar wind are examined. The model of Parker is emphasized. This model shows the three dimensional magnetic field lines of the solar wind to have the form of spirals wrapped on cones. It is concluded that an out-of-the-ecliptic solar probe mission would allow the testing and verification of the various theoretical models examined. Diagrams of the various models are shown.
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Software Risk Identification for Interplanetary Probes
NASA Technical Reports Server (NTRS)
Dougherty, Robert J.; Papadopoulos, Periklis E.
2005-01-01
The need for a systematic and effective software risk identification methodology is critical for interplanetary probes that are using increasingly complex and critical software. Several probe failures are examined that suggest more attention and resources need to be dedicated to identifying software risks. The direct causes of these failures can often be traced to systemic problems in all phases of the software engineering process. These failures have lead to the development of a practical methodology to identify risks for interplanetary probes. The proposed methodology is based upon the tailoring of the Software Engineering Institute's (SEI) method of taxonomy-based risk identification. The use of this methodology will ensure a more consistent and complete identification of software risks in these probes.
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DOE Office of Scientific and Technical Information (OSTI.GOV)
Gdalevich, G.L.; Afonin, V.V.; Eliseev, A.Y.
1986-07-01
Data from the Kosmos-900 satellite are used to examine variations of the ion concentration in the region of the main ionospheric trough at altitudes of about 500 km during the storm of December 18-19, 1978. These variations of ion densities are compared with the variations of the parameters of the interplanetary medium, in particular, with the E /sub y/ = -VB /sub z/ component of the interplanetary electric field. The results of the comparison are discussed. A scheme is proposed for the formation and motion of the trough during magnetic disturbances.
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Plasma and energetic particle structure of a collisionless quasi-parallel shock
NASA Technical Reports Server (NTRS)
Kennel, C. F.; Scarf, F. L.; Coroniti, F. V.; Russell, C. T.; Smith, E. J.; Wenzel, K. P.; Reinhard, R.; Sanderson, T. R.; Feldman, W. C.; Parks, G. K.
1983-01-01
The quasi-parallel interplanetary shock of November 11-12, 1978 from both the collisionless shock and energetic particle points of view were studied using measurements of the interplanetary magnetic and electric fields, solar wind electrons, plasma and MHD waves, and intermediate and high energy ions obtained on ISEE-1, -2, and -3. The interplanetary environment through which the shock was propagating when it encountered the three spacecraft was characterized; the observations of this shock are documented and current theories of quasi-parallel shock structure and particle acceleration are tested. These observations tend to confirm present self consistent theories of first order Fermi acceleration by shocks and of collisionless shock dissipation involving firehouse instability.
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Quasi-linear theory and transport theory. [particle acceleration in interplanetary medium
NASA Technical Reports Server (NTRS)
Smith, Charles W.
1992-01-01
The theory of energetic particle scattering by magnetostatic fluctuations is reviewed in so far as it fails to produce the rigidity-independent mean-free-paths observed. Basic aspects of interplanetary magnetic field fluctuations are reviewed with emphasis placed on the existence of dissipation range spectra at high wavenumbers. These spectra are then incorporated into existing theories for resonant magnetostatic scattering and are shown to yield infinite mean-free-paths. Nonresonant scattering in the form of magnetic mirroring is examined and offered as a partial solution to the magnetostatic problem. In the process, mean-free-paths are obtained in good agreement with observations in the interplanetary medium at 1 AU and upstream of planetary bow shocks.
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Automated Synthesis of Long Communication Delays for Testing
NASA Technical Reports Server (NTRS)
Seibert, Marc; McKim, James
2005-01-01
Planetary-Ohio Network Emulator (p- ONE) is a computer program for local laboratory testing of high bandwidth data-communication systems subject to long delays in propagation over interplanetary distances. p-ONE is installed on a personal computer connected to two bidirectional Ethernet interfaces, denoted A and B, that represent local-area networks at opposite ends of a long propagation path. Traffic that is to be passed between A and B is encapsulated in IP (Internet Protocol) packets (e.g., User Data Protocol, UDP). Intercepting this traffic between A and B in both directions, p-ONE time-tags each packet and stores it in memory or on the hard disk of the computer for a user-specified interval that equals the propagation delay to be synthesized. At the expiration of its storage time, each such packet is sent to its destination (that is, if it was received from A, it is sent to B, or vice versa). The accuracy of the p-ONE software is very high, with zero packet loss through the system and negligible latency. Optionally, p-ONE can be configured to delay all network traffic to and from all network addresses on each Ethernet interface or to selectively delay traffic between specific addresses or traffic of specific types. p-ONE works well with Linux and is also designed to be compatible with other operating systems.
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Temporal Variability in the Accretion Rate of Interplanetary Dust Using (3)He as a Tracer
NASA Technical Reports Server (NTRS)
Farley, K. A.
2005-01-01
The research supported by this grant falls under three topics: 1) Weekly Interplanetary Dust Sampling via (3)He; 2) Extraterrestrial (3)He at Major Impact Boundaries; 3) Completing a Moderately-High Resolution Record of Extraterrestrial (3)He Flux: A Major Asteroidal Break up Event at 8.2 Ma.
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The interplanetary pioneers. Volume 1: Summary
NASA Technical Reports Server (NTRS)
Corliss, W. R.
1972-01-01
The Pioneer Space Probe Project is explained to document the events which occurred during the project. The subjects discussed are: (1) origin and history of interplanetary Pioneer program, (2) Pioneer system development and design, (3) Pioneer flight operations, and (4) Pioneer scientific results. Line drawings, circuit diagrams, illustrations, and photographs are included to augment the written material.
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Towards an interplanetary internet: a proposed strategy for standardization
NASA Technical Reports Server (NTRS)
Hooke, A. J.
2002-01-01
This paper reviews the current set of standard data communications capabilities that exist to support advanced missions, discusses the architectural concepts for the future Interplanetary Internet, and suggests how a standardized set of space communications protocols that can grow to support future scenarios where human intelligence is widely distributed across the Solar System.
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Research in particles and fields. [using spacecraft and balloons
NASA Technical Reports Server (NTRS)
Vogt, R. E.
1974-01-01
Investigations, by particle-detectors flown on spacecraft, of the astrophysical aspects of cosmic radiation and the radiation environment of the earth are reported along with the research of the interplanetary medium, and planetary magnetic fields. The cosmic ray interactions with the interplanetary and interstellar medium, and radio scintillation theory were also studied.
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Solar events and their influence on the interplanetary medium
NASA Technical Reports Server (NTRS)
Joselyn, Joann
1987-01-01
Aspects of a workshop on Solar events and their influence on the interplanetary medium, held in September 1986, are reviewed, the goal of which was to foster interactions among colleagues, leading to an improved understanding of the unified relationship between solar events and interplanetary disturbances. The workshop consisted of three working groups: (1) flares, eruptives, and other near-Sun activity; (2) coronal mass ejections; and (3) interplanetary events. Each group discussed topics distributed in advance. The flares-eruptives group members agreed that pre-event energy is stored in stressed/sheared magnetic fields, but could not agree that flares and other eruptive events (e.g., eruptive solar prominences) are aspects of the same physical phenomenon. In the coronal mass ejection group, general agreement was reached on the presence of prominences in CMEs, and that they have a significant three-dimensional structure. Some topics identified for further research were the aftermath of CMEs (streamer deflections, transient coronal holes, possible disconnections), identification of the leading edge of CMEs, and studies of the range and prevalence of CME mass sizes and energies.
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NASA Technical Reports Server (NTRS)
Burch, J. L.
1972-01-01
Data from the auroral particles experiment on OGO-4 were used to study effects of substorm activity, interplanetary magnetic field latitutde, and dipole tilt angle on high-latitude precipitation of 700 eV electrons. It was found that: (1) The high-latitude zone of 700 eV electron precipitation in late evening and early morning hours moves equatorward by 5 to 10 deg during substorms. (2) The low-latitude boundary of polar cusp electron precipitation at 9 to 15 hours MLT also moves equatorward by several degrees during substorms and, in the absence of significant substorm activity, after a period of southward interplanetary magnetic field. (3) With times containing substorm activity or a southward interplanetary magnetic field eliminated, the low-latitude boundary of polar cusp electron precipitation is found to move by approximately 4 deg over the total yearly range of tilt angles. At maximum winter and summer conditions the invariant latitude of the boundary is shown to shift by approximately -3 deg and +1 deg respectively from its equinox location.
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Interplanetary dust. [survey of last four years' research
NASA Technical Reports Server (NTRS)
Brownlee, D. E.
1979-01-01
Progress in the study of interplanetary dust during the past four years is reviewed. Attention is given to determinations of the relative contributions of interstellar dust grains, collisional debris from the asteroid belt and short-period comets to the interplanetary dust cloud. Effects of radiation pressure and collisions on particle dynamics are discussed, noting the discovery of the variation of the orbital parameters of dust particles at 1 AU with size and in situ measurements of dust density between 0.3 and 5 AU by the Helios and Pioneer spacecraft. The interpretation of the zodiacal light as produced by porous absorbing particles 10 to 100 microns in size is noted, and measurements of the Doppler shift, light-producing-particle density, UV spectrum, photometric axis and angular scattering function of the zodiacal light are reported. Results of analyses of lunar rock microcraters as to micrometeoroid density, flux rate, size distribution and composition are indicated and interplanetary dust particles collected from the stratosphere are discussed. Findings concerning the composition of fragile meteoroid types found as cosmic spherules in deep sea sediments are also presented.
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The interplanetary electric field, cleft currents and plasma convection in the polar caps
NASA Technical Reports Server (NTRS)
Banks, P. M.; Clauer, C. R.; Araki, T.; St. Maurice, J. P.; Foster, J. C.
1984-01-01
The relationship between the pattern of plasma convection in the polar cleft and the dynamics of the interplanetary electric field (IEF) is examined theoretically. It is shown that owing to the geometrical properties of the magnetosphere, the East-West component of the IEF will drive field-aligned currents which connect to the ionosphere at points lying on either side of noon, while currents associated with the North-South component of the IEF will connect the two polar caps as sheet currents, also centered at 12 MLT. In order to describe the consequences of the Interplanetary Magnetic Field (IMF) effects upon high-latitude electric fields and convection patterns, a series of numerical simulations was carried out. The simulations were based on a solution to the steady-state equation of current continuity in a height-integrated ionospheric current. The simulations demonstrate that a simple hydrodynamical model can account for the narrow 'throats' of strong dayside antisunward convection observed during periods of southward interplanetary IMF drift, as well as the sunward convection observed during periods of strongly northward IMF drift.
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NASA Technical Reports Server (NTRS)
Holbrook, Mark; Pitts, Robert Lee; Gifford, Kevin K.; Jenkins, Andrew; Kuzminsky, Sebastian
2010-01-01
The International Space Station (ISS) is in an operational configuration and nearing final assembly. With its maturity and diverse payloads onboard, the opportunity exists to extend the orbital lab into a facility to exercise and demonstrate Delay/Disruption Tolerant Networking (DTN). DTN is an end-to-end network service providing communications through environments characterized by intermittent connectivity, variable delays, high bit error rates, asymmetric links and simplex links. The DTN protocols, also known as bundle protocols, provide a store-and-forward capability to accommodate end-to-end network services. Key capabilities of the bundling protocols include: the Ability to cope with intermittent connectivity, the Ability to take advantage of scheduled and opportunistic connectivity (in addition to always up connectivity), Custody Transfer, and end-to-end security. Colorado University at Boulder and the Huntsville Operational Support Center (HOSC) have been developing a DTN capability utilizing the Commercial Generic Bioprocessing Apparatus (CGBA) payload resources onboard the ISS, at the Boulder Payload Operations Center (POC) and at the HOSC. The DTN capability is in parallel with and is designed to augment current capabilities. The architecture consists of DTN endpoint nodes on the ISS and at the Boulder POC, and a DTN node at the HOSC. The DTN network is composed of two implementations; the Interplanetary Overlay Network (ION) and the open source DTN2 implementation. This paper presents the architecture, implementation, and lessons learned. By being able to handle the types of environments described above, the DTN technology will be instrumental in extending networks into deep space to support future missions to other planets and other solar system points of interest. Thus, this paper also discusses how this technology will be applicable to these types of deep space exploration missions.
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The response of ionospheric convection in the polar cap to substorm activity
NASA Technical Reports Server (NTRS)
Lester, M.; Lockwood, M.; Yeoman, T. K.; Cowley, S. W. H.; Luehr, H.; Bunting, R.; Farrugia, C. J.
1995-01-01
We report multi-instrument observations during an isolated substorm on 17 October 1989. The European Incoherent Scatter (EISCAT) radar operated in the SP-UK-POLI mode measuring ionospheric convection at latitudes 71 deg Lambda - 78 deg Lambda. Sub-Auroral Magnetometer Network (SAMNET) and the EISCAT Magnetometer Cross provide information on the timing of substorm expansion phase onset and subsequent intensifications, as well as the location of the field aligned and ionospheric currents associated with the substorm current wedge. Interplanetary Monitoring Platform-8 (IMP-8) magnetic field data are also included. Evidence of a substorm growth phase is provided by the equatorward motion of a flow reversal boundary across the EISCAT radar field of view at 2130 MLT, following a southward turning of the interplanetary magnetic field (IMF). We infer that the polar cap expanded as a result of the addition of open magnetic flux in the tail lobes during this interval. The flow reversal boundary, which is a lower limit to the polar cap boundary, reached an invariant latitude equatorward of 71 deg Lambda by the time of the expansion phase onset. We conclude that the substorm onset region in the ionosphere, defined by the westward electrojet, mapped to a part of the tail radially earthward of the boundary between open and closed magnetic flux, the distant neutral line. Thus the substorm was not initiated at the distant neutral line, although there is evidence that it remained active during the expansion phase.
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DOE Office of Scientific and Technical Information (OSTI.GOV)
Xiong, Ming; Yang, Liping; Liu, Ying D.
Interplanetary corotating interaction regions (CIRs) can be remotely imaged in white light (WL), as demonstrated by the Solar Mass Ejection Imager (SMEI) on board the Coriolis spacecraft and Heliospheric Imagers (HIs) on board the twin Solar TErrestrial RElations Observatory ( STEREO ) spacecraft. The interplanetary WL intensity, due to Thomson scattering of incident sunlight by free electrons, is jointly determined by the 3D distribution of electron number density and line-of-sight (LOS) weighting factors of the Thomson-scattering geometry. The 2D radiance patterns of CIRs in WL sky maps look very different from different 3D viewpoints. Because of the in-ecliptic locations ofmore » both the STEREO and Coriolis spacecraft, the longitudinal dimension of interplanetary CIRs has, up to now, always been integrated in WL imagery. To synthesize the WL radiance patterns of CIRs from an out-of-ecliptic (OOE) vantage point, we perform forward magnetohydrodynamic modeling of the 3D inner heliosphere during Carrington Rotation CR1967 at solar maximum. The mixing effects associated with viewing 3D CIRs are significantly minimized from an OOE viewpoint. Our forward modeling results demonstrate that OOE WL imaging from a latitude greater than 60° can (1) enable the garden-hose spiral morphology of CIRs to be readily resolved, (2) enable multiple coexisting CIRs to be differentiated, and (3) enable the continuous tracing of any interplanetary CIR back toward its coronal source. In particular, an OOE view in WL can reveal where nascent CIRs are formed in the extended corona and how these CIRs develop in interplanetary space. Therefore, a panoramic view from a suite of wide-field WL imagers in a solar polar orbit would be invaluable in unambiguously resolving the large-scale longitudinal structure of CIRs in the 3D inner heliosphere.« less
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NASA Astrophysics Data System (ADS)
Nurjannah, Yanah; Budianto, Emil
2018-04-01
Heliobacter pylori (H.pylori) is a type of bacteria that causes inflammation in the lining of the stomach. The treatment of the bacterial infection by using conventional medicine which is amoxicillin trihidrate has a very short retention time in the stomach which is about 1-1,5 hours. Floating drug delivery system is expected to have a long retention time in the stomach so the efficiency of drug can be achieved. In this study, has been synthesized matrix of semi-IPN chitosan-Poly(N-vinil pyrrolidone) hydrogel with a pore-forming agent of CaCO3 under optimum conditions. Amoxicillin is encapsulated in a matrix hydrogel to be applied as a floating drug delivery system by in situ loading and post loading methods. The encapsulation efficiency and dissolution of in situ loading and post loading hydrogels are performed in vitro on gastric pH. In situ loading hydrogel shows higer percentage of encapsulation efficiency and dissolution compared to post loading hydrogel. The encapsulation efficiency of in situ and post loading hydrogels were 92,1% and 89,4%, respectively. The aim of drug dissolution by mathematical equation model is to know kinetics and the mecanism of dissolution. The kinetics release of in situ hydrogel tends to follow first order kinetics, while the post loading hydrogel follow the Higuchi model. The dissolution mecanism of hydrogels is erosion.
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NASA Astrophysics Data System (ADS)
Fimantari, Khansa; Budianto, Emil
2018-04-01
Helicobacterpylori infection can be treated using trihydrate amoxicillin. However, this treatment is not effective enough, as the conventional dosage treatment has a relatively short retention time in the human stomach. In the present study, the amoxicillin trihydrate drug will be encapsulated into a semi-IPN K-PNVP hydrogel matrix with 7,5% KHCO3 as a pore-forming agent. The encapsulated drug is tested with in vitro method to see the efficiency of its encapsulation and dissolution. The hydrogel in situ loading produces an encapsulation efficiency value. The values of the encapsulation efficiency are 95% and 98%, while post loading hydrogel yields an encapsulation efficiency value is 77% and the dissolution is 84%. The study of drug dissolution mechanism was done by using mathematical equation model to know its kinetics and its mechanism of dissolution. The post loading hydrogel was done by using thefirst-order model, while hydrogel in situ loading used Higuchi model. The Korsmeyer-Peppas model shows that post loading hydrogel dissolution mechanism is a mixture of diffusion and erosion, and in situ loading hydrogel in the form of diffusion. It is supported by the results of hydrogel characterization, before and after dissolution test with an optical microscope. The results of the optical microscope show that the hydrogel surface before and after the dissolution tested for both methods shows the change becomes rougher.
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Ji, Feng; Zhao, Jing-Zhuang; Liu, Miao; Lu, Tong-Yan; Liu, Hong-Bai; Yin, Jiasheng; Xu, Li-Ming
2017-04-01
Infectious pancreatic necrosis (IPN) is a significant disease of farmed salmonids resulting in direct economic losses due to high mortality in China. However, no gene sequence of any Chinese infectious pancreatic necrosis virus (IPNV) isolates was available. In the study, moribund rainbow trout fry samples were collected during an outbreak of IPN in Yunnan province of southwest China in 2013. An IPNV was isolated and tentatively named ChRtm213. We determined the full genome sequence of the IPNV ChRtm213 and compared it with previously identified IPNV sequences worldwide. The sequences of different structural and non-structural protein genes were compared to those of other aquatic birnaviruses sequenced to date. The results indicated that the complete genome sequence of ChRtm213 strain contains a segment A (3099 nucleotides) coding a polyprotein VP2-VP4-VP3, and a segment B (2789 nucleotides) coding a RNA-dependent RNA polymerase VP1. The phylogenetic analyses showed that ChRtm213 strain fell within genogroup 1, serotype A9 (Jasper), having similarities of 96.3% (segment A) and 97.3% (segment B) with the IPNV strain AM98 from Japan. The results suggest that the Chinese IPNV isolate has relative closer relationship with Japanese IPNV strains. The sequence of ChRtm213 was the first gene sequence of IPNV isolates in China. This study provided a robust reference for diagnosis and/or control of IPNV prevalent in China.
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NASA Technical Reports Server (NTRS)
1975-01-01
Pioneer 10's encounter with Jupiter is discussed along with the interplanetary space beyond the orbit of Mars. Other topics discussed include the size of Jupiter, the Galilean satellites, the magnetic field of Jupiter, radiation belts, Jupiter's weather and interior, and future exploration possibilities. Educational projects are also included.
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Interplanetary dust - Trace element analysis of individual particles by neutron activation
NASA Technical Reports Server (NTRS)
Ganapathy, R.; Brownlee, D. E.
1979-01-01
Although micrometeorites of cometary origin are thought to be the dominant component of interplanetary dust, it has never been possible to positively identify such micrometer-sized particles. Two such particles have been identified as definitely micrometeorites since their abundances of volatile and nonvolatile trace elements closely match those of primitive solar system material.
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NASA Astrophysics Data System (ADS)
Tyul'Bashev, S. A.
2009-01-01
A complete sample of radio sources has been studied using the interplanetary scintillation method. In total, 32 sources were observed, with scintillations detected in 12 of them. The remaining sources have upper limits for the flux densities of their compact components. Integrated flux densities are estimated for 18 sources.
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Interplanetary monitoring platform engineering history and achievements
NASA Technical Reports Server (NTRS)
Butler, P. M.
1980-01-01
In the fall of 1979, last of ten Interplanetary Monitoring Platform Satellite (IMP) missions ended a ten year series of flights dedicated to obtaining new knowledge of the radiation effects in outer space and of solar phenomena during a period of maximum solar flare activity. The technological achievements and scientific accomplishments from the IMP program are described.
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On the causes of geomagnetic activity
NASA Technical Reports Server (NTRS)
Svalgaard, L.
1975-01-01
The causes of geomagnetic activity are studied both theoretically in terms of the reconnection model and empirically using the am-index and interplanetary solar wind parameters. It is found that two separate mechanisms supply energy to the magnetosphere. One mechanism depends critically on the magnitude and direction of the interplanetary magnetic field. Both depend strongly on solar wind speed.
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NASA Technical Reports Server (NTRS)
Marsden, R. G.; Sanderson, T. R.; Wenzel, K. P.; Smith, E. J.
1985-01-01
It is known that the interplanetary medium in the period approaching solar maximum is characterized by an enhancement in the occurrence of transient solar wind streams and shocks and that such systems are often associated with looplike magnetic structures or clouds. There is observational evidence that bidirectional, field aligned flows of low energy particles could be a signature of such looplike structures, although detailed models for the magnetic field configuration and injection mechanisms do not exist at the current time. Preliminary results of a survey of low energy proton bidirectional anisotropies measured on ISEE-3 in the interplanetary medium between August 1978 and May 1982, together with magnetic field data from the same spacecraft are presented.
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Cosmic-ray streaming and anisotropies
NASA Technical Reports Server (NTRS)
Forman, M. A.; Gleeson, L. J.
1975-01-01
The paper is concerned with the differential current densities and anisotropies that exist in the interplanetary cosmic-ray gas, and in particular with a correct formulation and simple interpretation of the momentum equation that describes these on a local basis. Two examples of the use of this equation in the interpretation of previous data are given. It is demonstrated that in interplanetary space, the electric-field drifts and convective flow parallel to the magnetic field of cosmic-ray particles combine as a simple convective flow with the solar wind, and that there exist diffusive currents and transverse gradient drift currents. Thus direct reference to the interplanetary electric-field drifts is eliminated, and the study of steady-state and transient cosmic-ray anisotropies is both more systematic and simpler.
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Tin in a chondritic interplanetary dust particle
NASA Technical Reports Server (NTRS)
Rietmeijer, Frans J. M.
1989-01-01
Submicron platey Sn-rich grains are present in chondritic porous interplanetary dust particle (IDP) W7029 A and it is the second occurrence of a tin mineral in a stratospheric micrometeorite. Selected Area Electron Diffraction data for the Sn-rich grains match with Sn2O3 and Sn3O4. The oxide(s) may have formed in the solar nebula when tin metal catalytically supported reduction of CO or during flash heating on atmospheric entry of the IDP. The presence of tin is consistent with enrichments for other volatile trace elements in chondritic IDPs and may signal an emerging trend toward nonchondritic volatile element abundances in chondritic IDPs. The observation confirms small-scale mineralogical heterogeneity in fine-grained chondritic porous interplanetary dust.
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NASA Technical Reports Server (NTRS)
Kyte, F. T.
1977-01-01
Meteor ablation debris was distinguished from unablated interplanetary dust in a collection of extraterrestrial particles collected in the stratosphere using NASA U-2 aircraft. A 62 g sample of the Murchison (C2) meteorite was artificially ablated to characterize ablation debris for comparison with the stratospheric particles. By using proper experimental conditions, artificial ablation debris can be produced that is similar to natural ablation debris. Analyses of natural fusion crusts, artificial fusion crust, and artificial ablation debris of the Murchison meteorite produced criteria for recognizing debris ablated by a primitive meteoroid. Ninety-five percent of the stratospheric particles can be described as either ablation debris from a primitive meteoroid, or as very primitive interplanetary dust.
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Modeling solar wind with boundary conditions from interplanetary scintillations
Manoharan, P.; Kim, T.; Pogorelov, N. V.; ...
2015-09-30
Interplanetary scintillations make it possible to create three-dimensional, time- dependent distributions of the solar wind velocity. Combined with the magnetic field observations in the solar photosphere, they help perform solar wind simulations in a genuinely time-dependent way. Interplanetary scintillation measurements from the Ooty Radio Astronomical Observatory in India provide directions to multiple stars and may assure better resolution of transient processes in the solar wind. In this paper, we present velocity distributions derived from Ooty observations and compare them with those obtained with the Wang-Sheeley-Arge (WSA) model. We also present our simulations of the solar wind flow from 0.1 AUmore » to 1 AU with the boundary conditions based on both Ooty and WSA data.« less
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NASA Astrophysics Data System (ADS)
St. Cyr, O. C.; Kaiser, M. L.; Meyer-Vernet, N.; Howard, R. A.; Harrison, R. A.; Bale, S. D.; Thompson, W. T.; Goetz, K.; Maksimovic, M.; Bougeret, J.-L.; Wang, D.; Crothers, S.
2009-05-01
Early in the STEREO mission observers noted that the white-light instruments of the SECCHI suite were detecting significantly more spacecraft-related “debris” than any previously flown coronagraphic instruments. Comparison of SECCHI “debris storms” with S/WAVES indicates that almost all are coincident with the most intense transient emissions observed by the radio and plasma waves instrument. We believe the debris is endogenous ( i.e., from the spacecraft thermal blanketing), and the storms appear to be caused by impacts of large interplanetary dust grains that are detected by S/WAVES. Here we report the observations, compare them to interplanetary dust distributions, and document a reminder for future spacebased coronagraphic instrument builders.
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Study of Travelling Interplanetary Phenomena (STIP) workshop travel
NASA Technical Reports Server (NTRS)
Wu, S. T.
1986-01-01
Thirty six abstracts are provided from the SCOSTEP/STIP Symposium on Retrospective Analyses and Future Coordinated Intervals held in Switzerland on June 10 to 12, 1985. Six American scientists participated in the symposium and their abstracts are also included. The titles of their papers are: (1) An analysis of near surface and coronal activity during STIP interval 12, by T. E. Gergely; (2) Helios images of STIP intervals 6, B. V. Jackson; (3) Results from the analysis of solar and interplanetary observations during STIP interval 7, S. R. Kane; (4) STIP interval 19, E. Cliver; (5) Hydrodynamic buoyancy force in the solar atmosphere, T. Yeh; and (6) A combined MHD modes for the energy and momentum transport from solar surface to interplanetary space, S. T. Wu.
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A Free-Return Earth-Moon Cycler Orbit for an Interplanetary Cruise Ship
NASA Technical Reports Server (NTRS)
Genova, Anthony L.; Aldrin, Buzz
2015-01-01
A periodic circumlunar orbit is presented that can be used by an interplanetary cruise ship for regular travel between Earth and the Moon. This Earth-Moon cycler orbit was revealed by introducing solar gravity and modest phasing maneuvers (average of 39 m/s per month) which yields close-Earth encounters every 7 or 10 days. Lunar encounters occur every 26 days and offer the chance for a smaller craft to depart the cycler and enter lunar orbit, or head for a Lagrange point (e.g., EM-L2 halo orbit), distant retrograde orbit (DRO), or interplanetary destination such as a near-Earth object (NEO) or Mars. Additionally, return-to-Earth abort options are available from many points along the cycling trajectory.
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A model of the open magnetosphere. [with field configuration based on Chapman-Ferraro theory
NASA Technical Reports Server (NTRS)
Kan, J. R.; Akasofu, S.-I.
1974-01-01
The Chapman-Ferraro image method is extended to construct an idealized model of the open magnetosphere that responds to a change of the interplanetary field direction as well as to a change of the field magnitude or of the solar wind momentum flux. The magnetopause of the present model is an infinite plane surface having a normal field component distribution that is consistent with the merging theory. An upper limit on the inward displacement of the magnetopause following a southward turning of the interplanetary field is obtained. The results are in fair agreement with a single event reported by Aubry et al. (1971). The model determines the field configuration and the total magnetic flux connecting the magnetosphere to interplanetary space.
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The solar origins of two high-latitude interplanetary disturbances
NASA Technical Reports Server (NTRS)
Hudson, H. S.; Acton, L. W.; Alexander, D.; Harvey, K. L.; Kurokawa, H.; Kahler, S.; Lemen, J. R.
1995-01-01
Two extremely similar interplanetary forward/reverse shock events, with bidirectional electron streaming were detected by Ulysses in 1994. Ground-based and Yohkoh/SXT observations show two strikingly different solar events that could be associated with them: an LDE flare on 20 Feb. 1994, and a extremely large-scale eruptive event on 14 April 1994. Both events resulted in geomagnetic storms and presumably were associated with coronal mass ejections. The sharply contrasting nature of these solar events argues against an energetic causal relationship between them and the bidirectional streaming events observed by Ulysses during its S polar passage. We suggest instead that for each pair of events. a common solar trigger may have caused independent instabilities leading to the solar and interplanetary phenomena.
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Microtensile bond strength of different acrylic teeth to high-impact denture base resins.
Colebeck, Amanda C; Monaco, Edward A; Pusateri, Christopher R; Davis, Elaine L
2015-01-01
This study evaluated the effect of denture base acrylic, denture tooth composition, and ridge-lap surface treatment on the microtensile bond strength (μTBS) of three commercially available denture teeth and two injection denture processing systems. Sixteen experimental groups were formed (n = 3), according to denture tooth surface treatment (no treatment or surface treatment recommended by the manufacturer), denture base processing technique and acrylic (SR-Ivocap-Ivocap Plus or Success-Lucitone 199), and tooth type-composition at bonding interface (BlueLine DCL-PMMA, Portrait IPN-PMMA, Phonares II-PMMA, Phonares II-NHC). Rectangular bar specimens with a 1 mm(2) cross sectional area were fabricated and subsequently thermocycled at 10,000 cycles between 5°C and 55°C with a 15-second dwell time. Select specimens underwent μTBS testing in a universal testing machine with a 1 kN load cell at 0.5 mm/min crosshead speed. Data were analyzed statistically by two and three-way ANOVA and Tukey post hoc test (α = 0.05). Mean μTBS ranged between 56.2 ± 5.6 and 60.8 ± 5.0 N/mm(2) for the Ivocap Plus specimens and 13.3 ± 5.12 to 60.1 ± 6.0 N/mm(2) for the Lucitone 199 specimens. Among the Ivocap specimens, BlueLine DCL and Phonares II NHC had significantly higher μTBS than Portrait IPN to Ivocap Plus acrylic. There were no statistically significant differences among Blueline, Phonares II PMMA, and Phonares II NHC, or between Phonares II PMMA and Portrait IPN. Within the Luctione 199 specimens, there was a significantly higher μTBS for BlueLine DCL and Phonares II NHC denture teeth with the manufacturer-recommended surface treatment when compared to control surface. BlueLine, Portrait, and Phonares II PMMA groups achieved significantly higher mean μTBS than the Phonares II NHC group. There were no statistically significant differences among BlueLine, Portrait, and Phonares II PMMA groups. When evaluating the μTBS of PMMA and NHC denture teeth to base resins, a stronger bond was achieved using materials produced by the same manufacturer. Within the Luctione 199 specimens, the Phonares II NHC group demonstrated significantly lower bond strength than other specimens, suggesting that gross ridge-lap reduction of NHC denture teeth is not recommended if a base acrylic by a different manufacturer from the tooth is going to be used. © 2014 American College of Prosthodontists.
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Initial Characterization of Optical Communications with Disruption-Tolerant Network Protocols
NASA Technical Reports Server (NTRS)
Schoolcraft, Joshua; Wilson, Keith
2011-01-01
Disruption-tolerant networks (DTNs) are groups of network assets connected with a suite of communication protocol technologies designed to mitigate the effects of link delay and disruption. Application of DTN protocols to diverse groups of network resources in multiple sub-networks results in an overlay network-of-networks with autonomous data routing capability. In space environments where delay or disruption is expected, performance of this type of architecture (such as an interplanetary internet) can increase with the inclusion of new communications mediums and techniques. Space-based optical communication links are therefore an excellent building block of space DTN architectures. When compared to traditional radio frequency (RF) communications, optical systems can provide extremely power-efficient and high bandwidth links bridging sub-networks. Because optical links are more susceptible to link disruption and experience the same light-speed delays as RF, optical-enabled DTN architectures can lessen potential drawbacks and maintain the benefits of autonomous optical communications over deep space distances. These environment-driven expectations - link delay and interruption, along with asymmetric data rates - are the purpose of the proof-of-concept experiment outlined herein. In recognizing the potential of these two technologies, we report an initial experiment and characterization of the performance of a DTN-enabled space optical link. The experiment design employs a point-to-point free-space optical link configured to have asymmetric bandwidth. This link connects two networked systems running a DTN protocol implementation designed and written at JPL for use on spacecraft, and further configured for higher bandwidth performance. Comparing baseline data transmission metrics with and without periodic optical link interruptions, the experiment confirmed the DTN protocols' ability to handle real-world unexpected link outages while maintaining capability of reliably delivering data at relatively high rates. Finally, performance characterizations from this data suggest performance optimizations to configuration and protocols for future optical-specific DTN space link scenarios.
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CCSDS Advanced Orbiting Systems Virtual Channel Access Service for QoS MACHETE Model
NASA Technical Reports Server (NTRS)
Jennings, Esther H.; Segui, John S.
2011-01-01
To support various communications requirements imposed by different missions, interplanetary communication protocols need to be designed, validated, and evaluated carefully. Multimission Advanced Communications Hybrid Environment for Test and Evaluation (MACHETE), described in "Simulator of Space Communication Networks" (NPO-41373), NASA Tech Briefs, Vol. 29, No. 8 (August 2005), p. 44, combines various tools for simulation and performance analysis of space networks. The MACHETE environment supports orbital analysis, link budget analysis, communications network simulations, and hardware-in-the-loop testing. By building abstract behavioral models of network protocols, one can validate performance after identifying the appropriate metrics of interest. The innovators have extended the MACHETE model library to include a generic link-layer Virtual Channel (VC) model supporting quality-of-service (QoS) controls based on IP streams. The main purpose of this generic Virtual Channel model addition was to interface fine-grain flow-based QoS (quality of service) between the network and MAC layers of the QualNet simulator, a commercial component of MACHETE. This software model adds the capability of mapping IP streams, based on header fields, to virtual channel numbers, allowing extended QoS handling at link layer. This feature further refines the QoS v existing at the network layer. QoS at the network layer (e.g. diffserv) supports few QoS classes, so data from one class will be aggregated together; differentiating between flows internal to a class/priority is not supported. By adding QoS classification capability between network and MAC layers through VC, one maps multiple VCs onto the same physical link. Users then specify different VC weights, and different queuing and scheduling policies at the link layer. This VC model supports system performance analysis of various virtual channel link-layer QoS queuing schemes independent of the network-layer QoS systems.
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Impasse-driven tutoring for reactive skill acquisition
NASA Technical Reports Server (NTRS)
Hill, Randall W., Jr.; Johnson, W. Lewis
1993-01-01
We are interested in developing effective performance-oriented training for the operation of systems that are used for monitor and control purposes. We have focused on one such system, the communications Link Monitor and Control (LMC) system used in NASA's Deep Space Network (DSN), which is a worldwide system for navigating, tracking and communicating with unmanned interplanetary spacecraft. The tasks in this domain are procedural in nature and require reactive, goal-oriented skills; we have previously described a cognitive model for problem solving that accounts for both novice and expert levels of behavior as well as how skill is acquired. Our cognitive modeling work in this task domain led us to make a number of predictions about tutoring that have influenced the design of the system described in this paper.
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Dust analysis on board the Destiny+ mission to 3200 Phaethon
NASA Astrophysics Data System (ADS)
Krüger, H.; Kobayashi, M.; Arai, T.; Srama, R.; Sarli, B. V.; Kimura, H.; Moragas-Klostermeyer, G.; Soja, R.; Altobelli, N.; Grün, E.
2017-09-01
The Japanese Destiny+ spacecraft will be launched to the active asteroid 3200 Phaethon in 2022. Among the proposed core payload is an in-situ dust instrument based on the Cassini Cosmic Dust Analyzer. We use the ESA Interplanetary Meteoroid Engineering Model (IMEM), to study detection conditions and fluences of interplanetary and interstellar dust with a dust analyzer on board Destiny+.
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On the backscatter of solar He II, 304 A radiation from interplanetary He/+/.
NASA Technical Reports Server (NTRS)
Paresce, F.; Bowyer, S.
1973-01-01
Backscatter of solar He II, 304 A radiation by interplanetary positive helium ions is shown to be insufficient to account for recent observations of this airglow radiation in the night sky at rocket altitudes. In fact, for most viewing directions, the expected intensities probably fall well below the sensitivity threshold of existing extreme ultraviolet instrumentation.
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Nonlinear Electromagnetic Waves and Spherical Arc-Polarized Waves in Space Plasmas
NASA Technical Reports Server (NTRS)
Tsurutani, B.; Ho, Christian M.; Arballo, John K.; Lakhina, Gurbax S.; Glassmeier, Karl-Heinz; Neubauer, Fritz M.
1997-01-01
We review observations of nonlinear plasma waves detected by interplanetary spacecraft. For this paper we will focus primarily on the phase-steepened properties of such waves. Plasma waves at comet Giacobini-Zinner measured by the International Cometary Explorer (ICE), at comets Halley and Grigg-Skjellerup measured by Giotto, and interplanetary Alfven waves measured by Ulysses, will be discussed and intercompared.
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Latitudinal Dependence of the Radial IMF Component - Interplanetary Imprint
NASA Technical Reports Server (NTRS)
Suess, S. T.; Smith, E. J.; Phillips, J.; Goldstein, B. E.; Nerney, S.
1996-01-01
Ulysses measurements have confirmed that there is no significant gradient with respect to heliomagnetic latitude in the radial component, B(sub r,), of the interplanetary magnetic field. There are two processes responsible for this observation. In the corona, the plasma beta is much less than 1, except directly above streamers, so both longitudinal and latitudinal (meridional) gradients in field strength will relax, due to the transverse magnetic pressure gradient force, as the solar wind carries magnetic flux away from the Sun. This happens so quickly that the field is essentially uniform by 5 solar radius. Beyond 10 solar radius, beta is greater than 1 and it is possible for a meridional thermal pressure gradient to redistribute magnetic flux - an effect apparently absent in Ulysses and earlier ICE and Interplanetary Magnetic Physics (IMP) data. We discuss this second effect here, showing that its absence is mainly due to the perpendicular part of the anisotropic thermal pressure gradient in the interplanetary medium being too small to drive significant meridional transport between the Sun and approx. 4 AU. This is done using a linear analytic estimate of meridional transport. The first effect was discussed in an earlier paper.
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Relativistic electron dropout echoes induced by interplanetary shocks
NASA Astrophysics Data System (ADS)
Schiller, Q.; Kanekal, S. G.; Boyd, A. J.; Baker, D. N.; Blake, J. B.; Spence, H. E.
2017-12-01
Interplanetary shocks that impact Earth's magnetosphere can produce immediate and dramatic responses in the trapped relativistic electron population. One well-studied response is a prompt injection capable of transporting relativistic electrons deep into the magnetosphere and accelerating them to multi-MeV energies. The converse effect, electron dropout echoes, are observations of a sudden dropout of electron fluxes observed after the interplanetary shock arrival. Like the injection echo signatures, dropout echoes can also show clear energy dispersion signals. They are of particular interest because they have only recently been observed and their causal mechanism is not well understood. In the analysis presented here, we show observations of electron drift echo signatures from the Relativistic Electron-Proton Telescope (REPT) and Magnetic Electron and Ion Sensors (MagEIS) onboard NASA's Van Allen Probes mission, which show simultaneous prompt enhancements and dropouts within minutes of the associated with shock impact. We show that the observations associated with both enhancements and dropouts are explained by the inward motion caused by the electric field impulse induced by the interplanetary shock, and either energization to cause the enhancement, or lack of a seed population to cause the dropout.
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NASA Technical Reports Server (NTRS)
Levasseur-Regourd, A. C.; Lasue, J.
2011-01-01
Interplanetary dust particles physical properties may be approached through observations of the solar light they scatter, specially its polarization, and of their thermal emission. Results, at least near the ecliptic plane, on polarization phase curves and on the heliocentric dependence of the local spatial density, albedo, polarization and temperature are summarized. As far as interpretations through simulations are concerned, a very good fit of the polarization phase curve near 1.5 AU is obtained for a mixture of silicates and more absorbing organics material, with a significant amount of fluffy aggregates. In the 1.5-0.5 AU solar distance range, the temperature variation suggests the presence of a large amount of absorbing organic compounds, while the decrease of the polarization with decreasing solar distance is indeed compatible with a decrease of the organics towards the Sun. Such results are in favor of the predominance of dust of cometary origin in the interplanetary dust cloud, at least below 1.5 AU. The implication of these results on the delivery of complex organic molecules on Earth during the LHB epoch, when the spatial density of the interplanetary dust cloud was orders of magnitude greater than today, is discussed.
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Sub-barrier fusion cross section measurements with STELLA
NASA Astrophysics Data System (ADS)
Heine, M.; Courtin, S.; Fruet, G.; Jenkins, D. G.; Montanari, D.; Adsley, P.; Beck, C.; Della Negra, S.; Dené, P.; Haas, F.; Hammache, F.; Heitz, G.; Kirsebom, O. S.; Krauth, M.; Lesrel, J.; Meyer, A.; Morris, L.; Regan, P. H.; Richer, M.; Rudigier, M.; de Séréville, N.; Stodel, C.
2018-01-01
The experimental setup STELLA (STELlar LAboratory) is designed for the measurement of deep sub-barrier light heavy ion fusion cross sections. For background suppression the γ-particle coincidence technique is used. In this project, LaBr3 detectors from the UK FATIMA (FAst TIMing Array) collaboration are combined with annular silicon strip detectors customized at IPHC-CNRS, Strasbourg, and the setup is located at Andromède, IPN, Orsay. The commissioning of the experimental approach as well as a sub-barrier 12C +12C → 24Mg∗ cross section measurement campaign are carried out.
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Committees and supporting organizations
NASA Astrophysics Data System (ADS)
2011-09-01
Advisory Committee:Organizing Committee: Marcello Baldo (Catania)Takaharu Otsuka (Tokyo), co-chair George Bertsch (Seattle)Michael Urban (Orsay), co-chair Jean-Paul Blaizot (Saclay)Taiichi Yamada (Yokohama) Michel Girod (Bruyères-le-Châtel)Nguyen van Giai (Orsay) Hisashi Horiuchi (Osaka)Shinichiro Fujii (Tokyo) Umberto Lombardo (Catania)Jérôme Margueron (Orsay) Gerd Röpke (Rostock)Kouichi Hagino (Sendai) Hiroyuki Sagawa (Aizu)Yoshiko Kanada-En'yo (Kyoto) Piet Van Isacker (Caen) Enrico Vigezzi (Milano) IPN logo EFES logo CNRS logo ihp logo
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Interplanetary magnetic field data book
NASA Technical Reports Server (NTRS)
King, J. H.
1975-01-01
An interplanetary magnetic field (IMF) data set is presented that is uniform with respect to inclusion of cislunar IMF data only, and which has as complete time coverage as presently possible over a full solar cycle. Macroscale phenomena in the interplanetary medium (sector structure, heliolatitude variations, solar cycle variations, etc.) and other phenomena (e.g., ground level cosmic-ray events) for which knowledge of the IMF with hourly resolution is necessary, are discussed. Listings and plots of cislunar hourly averaged IMP parameters over the period November 27, 1963, to May 17, 1974, are presented along with discussion of the mutual consistency of the IMF data used herein. The magnetic tape from which the plots and listings were generated, which is available from the National Space Science Data Center (NSSDC), is also discussed.
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NASA Technical Reports Server (NTRS)
Koontz, Steven L.; Rojdev, Kristina; Valle, Gerard D.; Zipay, John J.; Atwell, William S.
2013-01-01
The Hybrid Inflatable DSH combined with electric propulsion and high power solar-electric power systems offer a near TRL-now solution to the space radiation crew dose problem that is an inevitable aspect of long term manned interplanetary flight. Spreading program development and launch costs over several years can lead to a spending plan that fits with NASA's current and future budgetary limitations, enabling early manned interplanetary operations with space radiation dose control, in the near future while biomedical research, nuclear electric propulsion and active shielding research and development proceed in parallel. Furthermore, future work should encompass laboratory validation of HZETRN calculations, as previous laboratory investigations have not considered large shielding thicknesses and the calculations presented at these thicknesses are currently performed via extrapolation.
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NASA Technical Reports Server (NTRS)
Giorgini, Jon; Wong, S. Kuen; You, Tung-Han; Chadbourne, Pam; Lim, Lily
1995-01-01
The Magellan spacecraft has been aerobraked into a 197 x 541 km near-circular orbit around Venus from which it is conducting a high-resolution gravity mapping mission. This was the first interplanetary aerobrake maneuver and involved flying the spacecraft through the upper reaches of the Venusian atmosphere 730 times over a 70 day period. Round-trip light-time varied from 9.57 to 18.83 minutes during this period. Navigation for this dynamic phase of the Magellan mission was planned and executed in the face of budget-driven down-sizing with all spacecraft safe modes disabled and a flight-team one-third the size of comparable interplanetary missions. Successful execution of this manuever using spacecraft hardware not designed to operate in a planetary atmosphere, demonstrated a practical cost-saving technique for both large and small future interplanetary missions.
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Testing model for prediction system of 1-AU arrival times of CME-associated interplanetary shocks
NASA Astrophysics Data System (ADS)
Ogawa, Tomoya; den, Mitsue; Tanaka, Takashi; Sugihara, Kohta; Takei, Toshifumi; Amo, Hiroyoshi; Watari, Shinichi
We test a model to predict arrival times of interplanetary shock waves associated with coronal mass ejections (CMEs) using a three-dimensional adaptive mesh refinement (AMR) code. The model is used for the prediction system we develop, which has a Web-based user interface and aims at people who is not familiar with operation of computers and numerical simulations or is not researcher. We apply the model to interplanetary CME events. We first choose coronal parameters so that property of background solar wind observed by ACE space craft is reproduced. Then we input CME parameters observed by SOHO/LASCO. Finally we compare the predicted arrival times with observed ones. We describe results of the test and discuss tendency of the model.
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NASA Technical Reports Server (NTRS)
Witt, N.; Blum, P. W.; Ajello, J. M.
1981-01-01
The analysis of Mariner 10 observations of Lyman-alpha resonance radiation shows an increase of interplanetary neutral hydrogen densities above the solar poles. This increase is caused by a latitudinal variation of the solar wind velocity and/or flux. Using both the Mariner 10 results and other solar wind observations, the values of the solar wind flux and velocity with latitude are determined for several cases of interest. The latitudinal variation of interplanetary hydrogen gas, arising from the solar wind latitudinal variation, is shown to be most pronounced in the inner solar system. From this result it is shown that spacecraft Lyman-alpha observations are more sensitive to the latitudinal anisotropy for a spacecraft location in the inner solar system near the downwind axis.
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NASA Technical Reports Server (NTRS)
Niedner, Malcolm B., Jr.; Schwingenschuh, Konrad; Hoeksema, J. Todd; Dryer, Murray; Mcintosh, Patrick S.
1987-01-01
The encounters of five spacecraft with Halley's Comet during 6-14 March 1986 offered a unique opportunity to calibrate the solar-wind interaction with cometary plasmas as recorded by remote wide-field and narrow-field/narrowband imaging. Perhaps not generally recognized in the comet community is the additional opportunity offered by the Halley Armada to study the structure of the solar-wind and interplanetary magnetic field (IMF) in three dimensions using five sets of data obtained over similar time intervals and heliocentric distances, but at somewhat different heliolatitudes. In fact, the two problems, i.e., comet physics and the structure of the interplanetary medium, are coupled if one wants to understand what conditions pertained at the comet between the encounters. This relationship is discussed.
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NASA Astrophysics Data System (ADS)
Armano, M.; Audley, H.; Baird, J.; Bassan, M.; Benella, S.; Binetruy, P.; Born, M.; Bortoluzzi, D.; Cavalleri, A.; Cesarini, A.; Cruise, A. M.; Danzmann, K.; de Deus Silva, M.; Diepholz, I.; Dixon, G.; Dolesi, R.; Fabi, M.; Ferraioli, L.; Ferroni, V.; Finetti, N.; Fitzsimons, E. D.; Freschi, M.; Gesa, L.; Gibert, F.; Giardini, D.; Giusteri, R.; Grimani, C.; Grzymisch, J.; Harrison, I.; Heinzel, G.; Hewitson, M.; Hollington, D.; Hoyland, D.; Hueller, M.; Inchauspé, H.; Jennrich, O.; Jetzer, P.; Karnesis, N.; Kaune, B.; Korsakova, N.; Killow, C. J.; Laurenza, M.; Lobo, J. A.; Lloro, I.; Liu, L.; López-Zaragoza, J. P.; Maarschalkerweerd, R.; Mance, D.; Martín, V.; Martin-Polo, L.; Martino, J.; Martin-Porqueras, F.; Mateos, I.; McNamara, P. W.; Mendes, J.; Mendes, L.; Nofrarias, M.; Paczkowski, S.; Perreur-Lloyd, M.; Petiteau, A.; Pivato, P.; Plagnol, E.; Ramos-Castro, J.; Reiche, J.; Robertson, D. I.; Rivas, F.; Russano, G.; Sabbatini, F.; Slutsky, J.; Sopuerta, C. F.; Sumner, T.; Telloni, D.; Texier, D.; Thorpe, J. I.; Vetrugno, D.; Vitale, S.; Wanner, G.; Ward, H.; Wass, P.; Weber, W. J.; Wissel, L.; Wittchen, A.; Zambotti, A.; Zenoni, C.; Zweifel, P.
2018-02-01
Galactic cosmic-ray (GCR) energy spectra observed in the inner heliosphere are modulated by the solar activity, the solar polarity and structures of solar and interplanetary origin. A high counting rate particle detector (PD) aboard LISA Pathfinder, meant for subsystems diagnostics, was devoted to the measurement of GCR and solar energetic particle integral fluxes above 70 MeV n‑1 up to 6500 counts s‑1. PD data were gathered with a sampling time of 15 s. Characteristics and energy dependence of GCR flux recurrent depressions and of a Forbush decrease dated 2016 August 2 are reported here. The capability of interplanetary missions, carrying PDs for instrument performance purposes, in monitoring the passage of interplanetary coronal mass ejections is also discussed.
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Evidence of scattering effects on the sizes of interplanetary Type III radio bursts
NASA Technical Reports Server (NTRS)
Steinberg, J. L.; Hoang, S.; Dulk, G. A.
1985-01-01
An analysis is conducted of 162 interplanetary Type III radio bursts; some of these bursts have been observed in association with fast electrons and Langmuir wave events at 1 AU and, in addition, have been subjected to in situ plasma parameter measurements. It is noted that the sizes of burst sources are anomalously large, compared to what one would anticipate on the basis of the interplanetary plasma density distribution, and that the variation of source size with frequency, when compared with the plasma frequency variation measured in situ, implies that the source sizes expand with decreasing frequency to fill a cone whose apex is at the sun. It is also found that some local phenomenon near the earth controls the apparent size of low frequency Type III sources.
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Development and Characterization of Mechanically Robust, 3D-Printable Photopolymers
NASA Astrophysics Data System (ADS)
Sycks, Dalton George
3D printing has seen an explosion of interest and growth in recent years, especially within the biomedical space. Prized for its efficiency, ability to produce complex geometries, and facile material processing, additive manufacturing is rapidly being used to create medical devices ranging from orthopedic implants to tissue scaffolds. However, 3D printing is currently limited to a select few material choices, especially when one considers soft tissue replacement or augmentation. To this end, my research focuses on developing material systems that are simultaneously 1) 3D printable, 2) biocompatible, and 3) mechanically robust with properties appropriate for soft-tissue replacement or augmentation applications. Two systems were developed toward this goal: an interpenetrating network (IPN) hydrogel consisting of covalently crosslinked poly (ethylene glycol) diacrylate (PEGDA) and ionically crosslinked brown sodium alginate, and semi-crystalline thiol-ene photopolymers containing spiroacetal molecules in the polymer main-chain backbone. In addition to successfully being incorporated into existing 3D printing systems (extrusion-deposition for the PEGDA-alginate hydrogel and digital light processing for the thiol-ene polymers) both systems exhibited biocompatibility and superior thermomechanical properties such as tensile modulus, failure strain, and toughness. This work offers two fully-developed, novel polymer platforms with outstanding performance; further, structure-property relationships are highlighted and discussed on a molecular and morphological level to provide material insights that are useful to researchers and engineers in the design of highly tuned and mechanically robust polymers.