The benefits of in-group contact through physical activity involvement for health and well-being among Korean immigrants

PubMed Central

Kim, Junhyoung; Heo, Jinmoo; Kim, Jun

2014-01-01

This qualitative study is designed to examine the benefits of physical activity involvement with members of the same ethnic group. For this study, Korean immigrants who were members of Korean physical activity clubs such as badminton and tennis were selected as participants. Using a constructive grounded theory methodology, three themes were identified as benefits of physical activity involvement: (1) the experience of psychological well-being, (2) the creation of a unique cultural world, and (3) the facilitation of physical activity involvement. The findings of this study suggest that Korean immigrant participants gained various social, cultural, and psychological benefits by engaging in activities with other Korean immigrants. PMID:24875239

The benefits of in-group contact through physical activity involvement for health and well-being among Korean immigrants.

PubMed

Kim, Junhyoung; Heo, Jinmoo; Kim, Jun

2014-01-01

This qualitative study is designed to examine the benefits of physical activity involvement with members of the same ethnic group. For this study, Korean immigrants who were members of Korean physical activity clubs such as badminton and tennis were selected as participants. Using a constructive grounded theory methodology, three themes were identified as benefits of physical activity involvement: (1) the experience of psychological well-being, (2) the creation of a unique cultural world, and (3) the facilitation of physical activity involvement. The findings of this study suggest that Korean immigrant participants gained various social, cultural, and psychological benefits by engaging in activities with other Korean immigrants.

Confronting Analytical Dilemmas for Understanding Complex Human Interactions in Design-Based Research from a Cultural-Historical Activity Theory (CHAT) Framework

ERIC Educational Resources Information Center

Yamagata-Lynch, Lisa C.

2007-01-01

Understanding human activity in real-world situations often involves complicated data collection, analysis, and presentation methods. This article discusses how Cultural-Historical Activity Theory (CHAT) can inform design-based research practices that focus on understanding activity in real-world situations. I provide a sample data set with…

Marine Ecology Research Resource Units Grades 7-9. Draft.

ERIC Educational Resources Information Center

Contra Costa County Dept. of Education, Pleasant Hill, CA.

Project Marine Ecology Research (MER) is an ecological unit designed to involve secondary students in the study of the marine biome. The teachers are also involved with MER through inservice participation and materials preparation. The unit is designed to be incorporated within the existing science curriculum. Specifically, the activities concern…

The Electric Vehicle Challenge

ERIC Educational Resources Information Center

Roman, Harry T.

2010-01-01

This article describes a design activity that provides students with a solid understanding of the many issues involved with alternate energy system design. In this activity, students will be able to learn about electric vehicles and have the opportunity to design a way to recharge the batteries while the cars are parked in a commuter garage. The…

Development and Evaluation of an Undergraduate Multidisciplinary Project Activity in Engineering and Design

ERIC Educational Resources Information Center

Smith, David R.; Cole, Joanne

2012-01-01

The School of Engineering and Design Multidisciplinary Project (MDP) at Brunel University is a one week long project based activity involving first year undergraduate students from across the School subject areas of Electronic and Computer Engineering, Mechanical Engineering, Civil Engineering and Design. This paper describes the main aims of the…

Experiential Learning Theory as a Guide for Effective Teaching.

ERIC Educational Resources Information Center

Murrell, Patricia H.; Claxton, Charles S.

1987-01-01

David Kolb's experiential learning theory involves a framework useful in designing courses that meet needs of diverse learners. Course designs providing systematic activities in concrete experience, reflective observations, abstract conceptualization, and active experimentation will be sensitive to students' learning styles while challenging…

Bringing Person-Centeredness and Active Involvement into Reality

ERIC Educational Resources Information Center

Torenholt, Rikke; Engelund, Gitte; Willaing, Ingrid

2015-01-01

Purpose: The purpose of this paper is to examine the use and applicability of cultural probes--an explorative participatory method to gain insights into a person's life and thoughts--to achieve person-centeredness and active involvement in self-management education for people with chronic illness. Design/methodology/approach: An education toolkit…

Reading, Writing and Relevance.

ERIC Educational Resources Information Center

Hoffman, Mary

This monograph presents classroom activities that were designed to encourage children to read and write in a self-reliant and responsible manner. The activities were chosen for their relevance to the children involved and because the vocabulary involved was interesting, familiar, and worth remembering and using again. The topics are arranged in…

Fabric-based active electrode design and fabrication for health monitoring clothing.

PubMed

Merritt, Carey R; Nagle, H Troy; Grant, Edward

2009-03-01

In this paper, two versions of fabric-based active electrodes are presented to provide a wearable solution for ECG monitoring clothing. The first version of active electrode involved direct attachment of surface-mountable components to a textile screen-printed circuit using polymer thick film techniques. The second version involved attaching a much smaller, thinner, and less obtrusive interposer containing the active electrode circuitry to a simplified textile circuit. These designs explored techniques for electronic textile interconnection, chip attachment to textiles, and packaging of circuits on textiles for durability. The results from ECG tests indicate that the performance of each active electrode is comparable to commercial Ag/AgCl electrodes. The interposer-based active electrodes survived a five-cycle washing test while maintaining good signal integrity.

Planning for Program Design and Assessment Using Value Creation Frameworks

ERIC Educational Resources Information Center

Whisler, Laurel; Anderson, Rachel; Brown, Jenai

2017-01-01

This article explains a program design and planning process using the Value Creation Framework (VCF) developed by Wenger, Trayner, and de Laat (2011). The framework involves identifying types of value or benefit for those involved in the program, conditions and activities that support creation of that value, data that measure whether the value was…

New Jersey 4-H Marine Science Project. Leaders Guide.

ERIC Educational Resources Information Center

Jesuncosky, Betty Jean, Comp.

This guide contains a collection of activities which are designed to provide opportunities for 4-H voluteers and youth in New Jersey to get involved in learning about the marine environment. The guide is divided into five sections which deal with habitats, organisms, career exploration, community involvement, and additional marine activities. Each…

Pet Care Teaching Unit: 1st-3rd Grades.

ERIC Educational Resources Information Center

Peninsula Humane Society, San Mateo, CA.

Activities in this unit are designed to familiarize primary grade students with the responsibilities involved in pet ownership. Teaching plans are provided for a total of 12 lessons involving social studies, language arts, math, and health sciences. Activities adaptable for readers and non-readers focus on pet overpopulation, care of pets when…

Engaging parents to increase youth physical activity a systematic review.

PubMed

O'Connor, Teresia M; Jago, Russell; Baranowski, Tom

2009-08-01

Parents are often involved in interventions to engage youth in physical activity, but it is not clear which methods for involving parents are effective. A systematic review was conducted of interventions with physical activity and parental components among healthy youth to identify how best to involve parents in physical activity interventions for children. Identified intervention studies were reviewed in 2008 for study design, description of family components, and physical activity outcomes. The quality of reporting was assessed using the CONSORT checklist for reporting on trials of nonpharmacologic treatments. The literature search identified 1227 articles, 35 of which met review criteria. Five of the 14 RCTs met > or =70% of CONSORT checklist items. Five general procedures for involving parents were identified: (1) face-to-face educational programs or parent training, (2) family participatory exercise programs, (3) telephone communication, (4) organized activities, and (5) educational materials sent home. Lack of uniformity in reporting trials, multiple pilot studies, and varied measurements of physical activity outcomes prohibited systematic conclusions. Interventions with educational or training programs during family visits or via telephone communication with parents appear to offer some promise. There is little evidence for effectiveness of family involvement methods in programs for promoting physical activity in children, because of the heterogeneity of study design, study quality, and outcome measures used. There is a need to build an evidence base of more-predictive models of child physical activity that include parent and child mediating variables and procedures that can effect changes in these variables for future family-based physical activity interventions.

Designing Interventions that Last: A Classification of Environmental Behaviors in Relation to the Activities, Costs, and Effort Involved for Adoption and Maintenance

PubMed Central

Moore, Harriet E.; Boldero, Jennifer

2017-01-01

Policy makers draw on behavioral research to design interventions that promote the voluntary adoption of environmental behavior in societies. Many environmental behaviors will only be effective if they are maintained over the long-term. In the context of climate change and concerns about future water security, behaviors that involve reducing energy consumption and improving water quality must be continued indefinitely to mitigate global warming and preserve scarce resources. Previous reviews of environmental behavior have focused exclusively on factors related to adoption. This review investigates the factors that influence both adoption and maintenance, and presents a classification of environmental behaviors in terms of the activities, costs, and effort required for both adoption and maintenance. Three categories of behavior are suggested. One-off behaviors involve performing an activity once, such as purchasing an energy efficient washing machine, or signing a petition. Continuous behaviors involve the performance of the same set of behaviors for adoption and for maintenance, such as curbside recycling. Dynamic behaviors involve the performance of different behaviors for adoption and maintenance, such as revegetation. Behaviors can also be classified into four categories related to cost and effort: those that involve little cost and effort for adoption and maintenance, those that involve moderate cost and effort for adoption and maintenance, those that involve a high cost or effort for adoption and less for maintenance, and those that involve less cost or effort for adoption and a higher amount for maintenance. In order to design interventions that last, policy makers should consider the factors that influence the maintenance as well as the adoption of environmental behaviors. PMID:29163265

Empowering Prospective Teachers to Become Active Sense-Makers: Multimodal Modeling of the Seasons

NASA Astrophysics Data System (ADS)

Kim, Mi Song

2015-10-01

Situating science concepts in concrete and authentic contexts, using information and communications technologies, including multimodal modeling tools, is important for promoting the development of higher-order thinking skills in learners. However, teachers often struggle to integrate emergent multimodal models into a technology-rich informal learning environment. Our design-based research co-designs and develops engaging, immersive, and interactive informal learning activities called "Embodied Modeling-Mediated Activities" (EMMA) to support not only Singaporean learners' deep learning of astronomy but also the capacity of teachers. As part of the research on EMMA, this case study describes two prospective teachers' co-design processes involving multimodal models for teaching and learning the concept of the seasons in a technology-rich informal learning setting. Our study uncovers four prominent themes emerging from our data concerning the contextualized nature of learning and teaching involving multimodal models in informal learning contexts: (1) promoting communication and emerging questions, (2) offering affordances through limitations, (3) explaining one concept involving multiple concepts, and (4) integrating teaching and learning experiences. This study has an implication for the development of a pedagogical framework for teaching and learning in technology-enhanced learning environments—that is empowering teachers to become active sense-makers using multimodal models.

A framework for public involvement at the design stage of NHS health and social care research: time to develop ethically conscious standards.

PubMed

Pandya-Wood, Raksha; Barron, Duncan S; Elliott, Jim

2017-01-01

Researchers who conduct studies in health and social care are encouraged to involve the public as early as possible in the process of designing their studies. Before their studies are allowed to start researchers must seek approval from a Research Ethics Committee, which will assess whether the study is going to be safe and ethical for patients or healthy volunteers to take part in. The process of ethical review does not consider how researchers work with patients and the public early on to design their studies. Furthermore, there is no requirement for researchers to seek ethical approval for public involvement. However, in our work advising researchers about public involvement we have found that the ways in which researchers involve the public in the design of their studies are sometimes unintentionally unethical, and this is the focus of our paper. We have observed ten areas where ethical issues may arise because of the actions researchers may or may not take and which might consequently have a negative impact. Therefore, we have used these observations to develop a "framework" to help researchers and the public work together at the early design stage in ways that are ethical. Our intention for the framework is to help researchers be mindful of these ten areas and how easily ethical issues can arise. The framework suggests some ways to overcome the potential issues in each of the ten areas. The ten areas are: 1) Allocating sufficient time for public involvement; 2) Avoiding tokenism; 3) Registering research design stage public involvement work with NHS Research & Development Trust Office at earliest opportunity; 4) Communicating clearly from the outset; 5) Entitling public contributors to stop their involvement for any unstated reasons; 6) Operating fairness of opportunity; 7) Differentiating qualitative research methods and public involvement activities; 8) Working sensitively; 9) Being conscious of confidentiality and 10) Valuing, acknowledging and rewarding public involvement. We looked to see whether any other similar approaches to helping researchers address potential ethical issues when working with the public on designing studies have been published and to our knowledge none exist. Our framework is presented as a draft and believe that it would now benefit from input from researchers and the public to gauge how useful it is and whether there are any other possible situations that it might need to cover. The current paper highlights real life examples of how ethical issues can arise during public involvement activities at the research design stage. We refer to "the research design stage" as the time between the generation of the research ideas and when formal permissions to start the work including ethical approval are granted. We argue that although most researchers work ethically at this early stage, some may still benefit from being informed about ethically conscious approaches to involving the public. The paper highlights 10 ethical issues that we have observed with involving the public at the research design stage. We provide examples of these observed scenarios to illustrate the issues and make suggestions for how they can be avoided to help researchers become more ethically conscious when involving the public at the research design stage. Currently the draft framework comprises: 1) Allocating sufficient time for public involvement; 2) Avoiding tokenism; 3) Registering research design stage public involvement work with NHS Research & Development Trust Office at earliest opportunity; 4) Communicating clearly from the outset; 5) Entitling public contributors to stop their involvement for any unstated reasons; 6) Operating fairness of opportunity; 7) Differentiating qualitative research methods and public involvement activities; 8) Working sensitively; 9) Being conscious of confidentiality and 10) Valuing, acknowledging and rewarding public involvement. The draft framework will help researchers to recognise the ethical issues when involving the public and is intended to be used voluntarily in a self-regulatory way. We believe that the draft framework requires further consultation and input from the wider research community and the public before endorsement by national UK bodies such as INVOLVE and the Health Research Authority (HRA).

Evaluating public involvement in research design and grant development: Using a qualitative document analysis method to analyse an award scheme for researchers.

PubMed

Baxter, Susan; Muir, Delia; Brereton, Louise; Allmark, Christine; Barber, Rosemary; Harris, Lydia; Hodges, Brian; Khan, Samaira; Baird, Wendy

2016-01-01

The National Institute for Health Research (NIHR) Research Design Service (RDS) for Yorkshire and Humber has been running a public involvement funding scheme since 2008. This scheme awards researchers a small amount of money to help them get involvement from patients and/or the public. Involvement activities take place at the time when researchers are planning studies, and when they are completing application forms to request funding for a proposed research project. After the public involvement activities researchers are asked to write a report for the RDS describing what they did with the public involvement funding. This study analysed those reports using an approach which included members of a public involvement panel in the data analysis process. The aim of the work was to see what the views and experiences of researchers who received funding were, and what might be learned for the future of the scheme. Twenty five reports were analysed. Four main themes were identified, these described: the added value of public involvement; aspects to consider when planning and designing public involvement; different roles of public contributors; and aspects of valuing public member contributions. The group approach to analysis was successful in enabling involvement of a variety of individuals in the process. The findings of the study provide evidence of the value of public involvement during the development of applications for research funding. The results also indicate that researchers recognise the variety in potential roles for the public in research, and acknowledge how involvement adds value to studies. Background A regional Research Design Service, funded by the National Institute for Health Research, introduced a small grant in 2008, to support public involvement (often known as patient and public involvement [PPI]) activities during the development of applications for research funding. Successful applicants are requested to submit a report detailing how the grant money was used, including a description of the aims and outcomes of the public involvement activities. The purpose of this study was to analyse the content of these reports. We aimed to find out what researcher views and experiences of public involvement activities were, and what lessons might be learned. Methods We used an innovative method of data analysis, drawing on group participatory approaches, qualitative content analysis, and Framework Analysis to sort and label the content of the reports. We developed a framework of categories and sub-categories (or themes and sub-themes) from this process. Results Twenty five documents were analysed. Four main themes were identified in the data: the added value of public involvement; planning and designing involvement; the role of public members; and valuing public member contributions. Within these themes, sub-themes related to the timing of involvement (prior to the research study/intended during the research study), and also specific benefits of public involvement such as: validating ideas; ensuring appropriate outcomes; ensuring the acceptability of data collection methods/tools and advice regarding research processes. Other sub-themes related to: finding and approaching public members; timing of events; training/support; the format of sessions; setting up public involvement panels: use of public contributors in analysis and interpretation of data; and using public members to assist with dissemination and translation into practice. Conclusions The analysis of reports submitted by researchers following involvement events provides evidence of the value of public involvement during the development of applications for research funding, and details a method for involving members of the public in data analysis which could be of value to other researchers The findings of the analysis indicate recognition amongst researchers of the variety in potential roles for public members in research, and also an acknowledgement of how involvement adds value to studies.

Actividades Para Padres: A Parent Handbook (Activities for Parents: A Parent Handbook).

ERIC Educational Resources Information Center

Coca, Benjamin

Thirty Mora, New Mexico parents attended a 13-session parent involvement workshop (The Mora Adventure) designed to help parents foster successful school experiences through non-school activities with their children. A parent involvement model was used as the basis of the workshop in which the parents developed more effective communication skills;…

Enhancing public involvement in assistive technology design research.

PubMed

Williamson, Tracey; Kenney, Laurence; Barker, Anthony T; Cooper, Glen; Good, Tim; Healey, Jamie; Heller, Ben; Howard, David; Matthews, Martin; Prenton, Sarah; Ryan, Julia; Smith, Christine

2015-05-01

To appraise the application of accepted good practice guidance on public involvement in assistive technology research and to identify its impact on the research team, the public, device and trial design. Critical reflection and within-project evaluation were undertaken in a case study of the development of a functional electrical stimulation device. Individual and group interviews were undertaken with lay members of a 10 strong study user advisory group and also research team members. Public involvement was seen positively by research team members, who reported a positive impact on device and study designs. The public identified positive impact on confidence, skills, self-esteem, enjoyment, contribution to improving the care of others and opportunities for further involvement in research. A negative impact concerned the challenge of engaging the public in dissemination after the study end. The public were able to impact significantly on the design of an assistive technology device which was made more fit for purpose. Research team attitudes to public involvement were more positive after having witnessed its potential first hand. Within-project evaluation underpins this case study which presents a much needed detailed account of public involvement in assistive technology design research to add to the existing weak evidence base. The evidence base for impact of public involvement in rehabilitation technology design is in need of development. Public involvement in co-design of rehabilitation devices can lead to technologies that are fit for purpose. Rehabilitation researchers need to consider the merits of active public involvement in research.

Participatory Design, User Involvement and Health IT Evaluation.

PubMed

Kushniruk, Andre; Nøhr, Christian

2016-01-01

End user involvement and input into the design and evaluation of information systems has been recognized as being a critical success factor in the adoption of information systems. Nowhere is this need more critical than in the design of health information systems. Consistent with evidence from the general software engineering literature, the degree of user input into design of complex systems has been identified as one of the most important factors in the success or failure of complex information systems. The participatory approach goes beyond user-centered design and co-operative design approaches to include end users as more active participants in design ideas and decision making. Proponents of participatory approaches argue for greater end user participation in both design and evaluative processes. Evidence regarding the effectiveness of increased user involvement in design is explored in this contribution in the context of health IT. The contribution will discuss several approaches to including users in design and evaluation. Challenges in IT evaluation during participatory design will be described and explored along with several case studies.

Activities involving aeronautical, space science, and technology support for minority institutions

NASA Technical Reports Server (NTRS)

1993-01-01

The Final Report addressed the activities with which the Interracial Council for Business Opportunity (ICBO) was involved over the past 12 months. ICBO was involved in the design and development of a CARES Student Tracking System Software (CARES). Cares is intended to provide an effective means of maintaining relevant current and historical information on NASA-funded students through a range of educational program initiatives. ICBP was extensively involved in the formation of a minority university consortium amd implementation of collaborative research activities by the consortium as part of NASA's Mission to Planet Earth/Earth Observing System. ICBO was involved in the formation of an HBCU/MI Consortium to facilitate technology transfer efforts to the small and minority business community in their respective regions.

Using a Complex and Nonlinear Pedagogical Approach to Design Practical Primary Physical Education Lessons

ERIC Educational Resources Information Center

Atencio, Matthew; Chow, Jia Yi; Tan, Wee Keat Clara; Lee, Chang Yi Miriam

2014-01-01

This paper describes several practical activities that reveal how complex and nonlinear pedagogies might underpin primary physical education and school sport lessons. These sample activities, involving track and field, tennis and netball components, are designed to incorporate states of stability and instability through the modification of task…

76 FR 59664 - Notice of Intent To Prepare an Environmental Impact Statement For Divert Activities and Exercises...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-27

... Mariana Islands. The proposed divert activities and exercises would involve airfield improvements designed... designed to support up to one tanker squadron of 12 KC-135 aircraft and its approximately 500 support... delivery capability; and associated pavement markings, lighting, security, and other related infrastructure...

Getting the Most from Working with Higher Education: A Review of Methods Used within a Participatory Design Activity Involving KS3 Special School Pupils and Undergraduate and Post-Graduate Industrial Design Students

ERIC Educational Resources Information Center

Torrens, George Edward; Newton, Helen

2013-01-01

This paper provides education-based researchers and practitioners with the preferred research and design methods used by Higher Education Institute (HEI) students and Key Stage 3 (KS3) pupils applied within a participatory approach to a design activity. The outcomes were that both pupils and students found informal (unstructured) interview to be…

Poetry-Teaching Tools.

ERIC Educational Resources Information Center

Murray, John J.

1965-01-01

Three game approaches to the teaching of poetry, designed to make the student actively involved with poems are described as "teaching tools." The semantico-dictionary or word-cross game involves programing techniques, logic, and lexicography in poetic analysis. The punched-out poem game involves filling in the blanks of a poem in which all the…

Minority Interest.

ERIC Educational Resources Information Center

Carter, Lindy Keane

1988-01-01

Brown University's Third World Alumni Activities Program is described. The program is designed to get alumni of African, Hispanic, Asian, or Native American descent involved in alumni activities, student recruitment, and fund raising. (MLW)

Designing an Earthquake-Resistant Building

ERIC Educational Resources Information Center

English, Lyn D.; King, Donna T.

2016-01-01

How do cross-bracing, geometry, and base isolation help buildings withstand earthquakes? These important structural design features involve fundamental geometry that elementary school students can readily model and understand. The problem activity, Designing an Earthquake-Resistant Building, was undertaken by several classes of sixth- grade…

Terrestrial Planet Finder Coronagraph : technology and mission design studies

NASA Technical Reports Server (NTRS)

Ford, Virginia G.

2004-01-01

The Terrestrial Planet Finder (TPF) coronagraph study involves exploring the technologies that enable a coronagraph style instrument to image and characterize earth-like planets orbiting nearby stars. Testbeds have been developed to demonstrate the emerging technologies needed for this effort and an architecture study has resulted in designs of a facility that will provide the environment needed for the technology to function in this role. A broad community of participants is involved in this work through studies, analyses, fabrication of components, and participation in the design effort. The scope of activities - both on the technology side and in the architecture study side - will be presented in this paper. The status and the future plans of the activities will be reviewed.

Implementation of a Program To Actively Involve Parents in the Education of Their Fourth-Grade Children by Participating in School Activities.

ERIC Educational Resources Information Center

Chisom, Yvette L.

An elementary school teacher in an urban school serving economically disadvantaged and middle-class black students implemented a practicum designed to increase involvement of parents of intermediate grade students in their children's education. Parent participation was mandatory in preschool and primary programs. But when children entered the…

Transitioning to a New Facility: The Crucial Role of Employee Engagement.

PubMed

Slosberg, Meredith; Nejati, Adeleh; Evans, Jennie; Nanda, Upali

Transitioning to a new facility can be challenging for employees and detrimental to operations. A key aspect of the transition is employee understanding of, and involvement in, the design of the new facility. The literature lacks a comprehensive study of the impact of change engagement throughout the design, construction, and activation of a project as well as how that can affect perceptions, expectations, and, eventually, satisfaction of employees. The purpose of this research was to examine employee perceptions and satisfaction throughout a hospital design, construction, and activation process. Three pulse-point surveys were administered throughout the transition of a children's hospital emergency department and neonatal intensive care unit to a new facility. We also administered a postoccupancy survey 3 months after the move into the new facility. We received 544 responses and analyzed them to assess the relationship between involvement in design or change engagement initiatives and overall perceptions. The results revealed a strong relationship between employee engagement and their level of preparedness to move, readiness to adapt, and satisfaction. Early involvement in the design of a facility or new processes can significantly affect staff preparedness and readiness to adapt as well as employees' overall satisfaction with the building after occupancy. In addition, our findings suggest that keeping a finger on the pulse of employee perceptions and expectations throughout the design, construction, and activation phase is critical to employee preparedness and satisfaction in transitioning to a new facility.

The Complex Dynamics of Student Engagement in Novel Engineering Design Activities

NASA Astrophysics Data System (ADS)

McCormick, Mary

In engineering design, making sense of "messy," design situations is at the heart of the discipline (Schon, 1983); engineers in practice bring structure to design situations by organizing, negotiating, and coordinating multiple aspects (Bucciarelli, 1994; Stevens, Johri, & O'Connor, 2014). In classroom settings, however, students are more often given well-defined, content-focused engineering tasks (Jonassen, 2014). These tasks are based on the assumption that elementary students are unable to grapple with the complexity or open-endedness of engineering design (Crismond & Adams, 2012). The data I present in this dissertation suggest the opposite. I show that students are not only able to make sense of, or frame (Goffman, 1974), complex design situations, but that their framings dynamically involve their nascent abilities for engineering design. The context of this work is Novel Engineering, a larger research project that explores using children's literature as an access point for engineering design. Novel Engineering activities are inherently messy: there are characters with needs, settings with implicit constraints, and rich design situations. In a series of three studies, I show how students' framings of Novel Engineering design activities involve their reasoning and acting as beginning engineers. In the first study, I show two students whose caring for the story characters contributes to their stability in framing the task: they identify the needs of their fictional clients and iteratively design a solution to meet their clients' needs. In the second, I show how students' shifting and negotiating framings influence their engineering assumptions and evaluation criteria. In the third, I show how students' coordinating framings involve navigating a design process to meet clients' needs, classroom expectations, and technical requirements. Collectively, these studies contribute to literature by documenting students' productive beginnings in engineering design. The implications span research and practice, specifically targeting how we attend to and support students as they engage in engineering design.

Recycling: Activities for the Classroom.

ERIC Educational Resources Information Center

Bowman, Mary Lynne, Comp.; Coon, Herbert L., Comp.

This publication provides 80 classroom activities for the teacher. These activities are designed for elementary through high school students and are action-oriented for participation in the school community. Each activity is classified according to appropriate grade level, subject matter, and recycling concept involved. In addition, each activity…

"How Long Is a Piece of String?"

ERIC Educational Resources Information Center

Aitchison, Kate

2001-01-01

Provides a lesson plan designed to form three one-hour sessions with mixed ability groups of 11-12 year olds. The activity involves students estimating road distances by counting the number of map grid lines crossed in going from A to B. The activity is designed to introduce students to graphing calculators. Screenshots from the calculator are…

10 CFR 60.2 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... which incompatible activities would be restricted following permanent closure. Design bases means that... natural events to be used for deriving design bases that will be based on consideration of historical data... involved; and (2) Estimates of severe external man-induced events, to be used for deriving design bases...

10 CFR 60.2 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... which incompatible activities would be restricted following permanent closure. Design bases means that... natural events to be used for deriving design bases that will be based on consideration of historical data... involved; and (2) Estimates of severe external man-induced events, to be used for deriving design bases...

Religious Involvement, Coping, Social Support, and Psychological Distress in HIV-Seropositive African American Mothers

PubMed Central

Prado, Guillermo; Feaster, Daniel J.; Schwartz, Seth J.; Pratt, Indira Abraham; Smith, Lila; Szapocznik, Jose

2005-01-01

This study used a cross-sectional design to examine the role of religious involvement within a stress-process framework. Participants were 252 urban, low-income HIV-seropositive African American mothers. The relationships among religious involvement, stress, coping responses, social support, and psychological distress were examined using structural equation modeling. The number of stressors reported by the mother was related to greater religious involvement, which in turn was negatively related to psychological distress. Furthermore, the results suggest that social support, active coping, and avoidant coping responses mediated the relationship between religious involvement and psychological distress. According to the present results, interventions to attenuate psychological distress in HIV-seropositive African American mothers might focus on increasing social support, promoting active coping, and decreasing avoidant coping. The present findings suggest that this may be accomplished, in part, by promoting involvement in religious institutions and practices. However, in light of the cross-sectional design used in the present study, and given that religion may have both positive and negative consequences further research is needed to determine the extent to which promoting religiosity may increase or alleviate distress. PMID:15475672

Space & Materials: A Second Year Design Curriculum.

ERIC Educational Resources Information Center

Ziff, Matthew

Design students provide a constant source of energy that moves into the mainstream of society. Their energy needs to be directed toward improving the characteristics of the built environment at every physical and economic scale of activity. Teaching design involves a broad range of decisions on how to present relevant design education content to…

Designing the safety of healthcare. Participation of ergonomics to the design of cooperative systems in radiotherapy.

PubMed

Munoz, Maria Isabel; Bouldi, Nadia; Barcellini, Flore; Nascimento, Adelaide

2012-01-01

This communication deals with the involvement of ergonomists in a research-action design process of a software platform in radiotherapy. The goal of the design project is to enhance patient safety by designing a workflow software that supports cooperation between professionals producing treatment in radiotherapy. The general framework of our approach is the ergonomics management of a design process, which is based in activity analysis and grounded in participatory design. Two fields are concerned by the present action: a design environment which is a participatory design process that involves software designers, caregivers as future users and ergonomists; and a reference real work setting in radiotherapy. Observations, semi-structured interviews and participatory workshops allow the characterization of activity in radiotherapy dealing with uses of cooperative tools, sources of variability and non-ruled strategies to manage the variability of the situations. This production of knowledge about work searches to enhance the articulation between technocentric and anthropocentric approaches, and helps in clarifying design requirements. An issue of this research-action is to develop a framework to define the parameters of the workflow tool, and the conditions of its deployment.

The neural correlates of strategic reading comprehension: cognitive control and discourse comprehension.

PubMed

Moss, Jarrod; Schunn, Christian D; Schneider, Walter; McNamara, Danielle S; Vanlehn, Kurt

2011-09-15

Neuroimaging studies of text comprehension conducted thus far have shed little light on the brain mechanisms underlying strategic learning from text. Thus, the present study was designed to answer the question of what brain areas are active during performance of complex reading strategies. Reading comprehension strategies are designed to improve a reader's comprehension of a text. For example, self-explanation is a complex reading strategy that enhances existing comprehension processes. It was hypothesized that reading strategies would involve areas of the brain that are normally involved in reading comprehension along with areas that are involved in strategic control processes because the readers are intentionally using a complex reading strategy. Subjects were asked to reread, paraphrase, and self-explain three different texts in a block design fMRI study. Activation was found in both executive control and comprehension areas, and furthermore, learning from text was associated with activation in the anterior prefrontal cortex (aPFC). The authors speculate that the aPFC may play a role in coordinating the internal and external modes of thought that are necessary for integrating new knowledge from texts with prior knowledge. Copyright © 2011 Elsevier Inc. All rights reserved.

[Design of new anti-tumor agents interrupting deregulated signaling pathways induced by tyrosine kinase proteins. Inhibition of protein-protein interaction involving Grb2].

PubMed

Vidal, Michel; Liu, Wang Qing; Gril, Brunile; Assayag, Franck; Poupon, Marie-France; Garbay, Christiane

2004-01-01

Cellular signaling pathways induced by growth-factor receptors are frequently deregulated in cancer. Anti-tumor agents that inhibit their enzymatic tyrosine kinase activity have been designed and are now used in human chemotherapy. We propose here an alternative way to interrupt over-expressed signaling by inhibiting protein-protein interactions that involve either the over-expressed proteins or proteins located downstream. The adaptor protein Grb2 over-expressed in connection with HER2/ErbB2/neu in Ras signaling pathway was chosen as a target. Peptides with very high affinity for Grb2 were rationally designed from structural data. Their capacity to interrupt the signaling pathway, their anti-proliferative activity as well as their potential anti-tumor properties are described.

Investigate-and-redesign tasks as a context for learning and doing science and technology: A study of naive, novice and expert high school and adult designers doing product comparisons and redesign tasks

NASA Astrophysics Data System (ADS)

Crismond, David Paul

This thesis studied high school students and adults with varying degrees of design experience doing two technology investigate-and-redesign (I&R) tasks. Each involved subjects investigating products, designing experiments to compare them fairly, and then redesigning the devices. A total of 25 pairs of subjects participated in this investigation and included naive and novice high school designers, as well as naive, novice, and expert adult designers. Subjects of similar age and design experience worked in same-gender teams and met for two 2-hour sessions. The essential research question of this thesis was: "What process skills and concepts do naive, novice and expert designers use and learn when investigating devices, designing experiments, and redesigning the devices?" Three methodologies were used to gather and analyze the data: clinical interviewing (Piaget, 1929/1960), protocol analysis (Ericsson & Simon, 1984) and interaction analysis (Jordan and Henderson, 1995). The thesis provides composite case-studies of 10 of the 50 test sessions, buttressed by descriptions of performance trends for all subjects. Given the small sample sizes involved, the findings are by necessity tentative and not supported by statistical analysis: (1) I&R activities are engaging, less time-intensive complements to design-and-build tasks, which involve simple mechanical devices and carry with them a host of potential "alternative understandings" in science and technology. Much gets learned during these tasks, more involving "device knowledge" and "device inquiry skills" than "big ideas" in science and technology. (2) Redesign tasks scaffold naive and novice designers to improved performance in the multidimensional and context-specific activity of design. The performances of naive and novice designers were more like that of expert designers when redesigning existing devices than when doing start-from-scratch designing. (3) Conceptual redesign involved more analysis- than synthesis-related design strategies, suggesting that opportunities for teaching science and technology during design are present, but underutilized since only experts made frequent connections to key science concepts. (4) Naive subjects focused mostly on product features and functions in their designs and made analogies mostly to concrete objects, while experts focused more on problem-finding, determining appropriate mechanisms, and made connections using analogies and concepts at both abstract and concrete levels.

Compendium of Interdisciplinary Activities for an Introductory Course in Communication Systems at the Secondary Level.

ERIC Educational Resources Information Center

Lasko, David J.

This compendium of interdisciplinary learning activities is designed to assist technology education instructors who are conducting an introductory secondary-level course in communication technology. The 12 activities, which are sequenced from introductory, low-cost activities to more advanced and more involved activities, deal with the following…

Health Activities Project (HAP): Breathing Fitness Module.

ERIC Educational Resources Information Center

Buller, Dave; And Others

Contained within this Health Activities Project (HAP) learning packet are activities for children in grades 5-8. Design of the activities centers around the idea that students can control their own health and safety. Within this module are teacher and student folios describing four activities which involve students in learning how to measure their…

Health Activities Project (HAP): Sight and Sound Module.

ERIC Educational Resources Information Center

Buller, Dave; And Others

Contained within this Health Activities Project (HAP) learning packet are activities for children in grades 5-8. Design of the activities centers around the idea that students can control their own health and safety. Within this module are teacher and student folios describing six activities which involve students in restricting their vision by…

Health Activities Project (HAP): Heart Fitness and Action Module.

ERIC Educational Resources Information Center

Buller, Dave; And Others

Contained within this Health Activities Project (HAP) learning packet are activities for children in grades 5-8. Design of the activities centers around the idea that students can control their own health and safety. Within the Heart Fitness and Action Module are teacher and student folios describing five activities which involve students in…

Explaining Physical Activity in Children with Visual Impairments: A Family Systems Approach

ERIC Educational Resources Information Center

Ayvazoglu, Nalan R.; Oh, Hyun-Kyoung; Kozub, Francis M.

2006-01-01

Using a mixed design this study explored physical activity in children with visual impairments from a family perspective. Quantitative findings revealed varied amounts of physical activity; younger children were more active than older participants. Further, parents were involved in moderate to vigorous physical activity 0% to 21% of the time when…

Design Research on Inquiry-Based Multivariable Calculus: Focusing on Students' Argumentation and Instructional Design

ERIC Educational Resources Information Center

Kwon, Oh Nam; Bae, Younggon; Oh, Kuk Hwan

2015-01-01

In this study, researchers design and implement an inquiry based multivariable calculus course in a university which aims at enhancing students' argumentation in rich mathematical discussions. This research aims to understand the characteristics of students' argumentation in activities involving proof constructions through mathematical…

Political Involvement. Community Involvement/Career Education: An Experience-based Social Studies Program, Volume III.

ERIC Educational Resources Information Center

Kyle, James; And Others

This collection of materials and ideas is designed for the high school student who wants to try to influence society. The guide provides background information and descriptions of experience-based learning activities for use by students as they explore political involvement opportunities in their communities. The purposes of the materials are to…

76 FR 77538 - Family and Youth Services Bureau; Proposed Information Collection Activity; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-13

...) evaluation design, which will involve baseline surveys and two follow-up surveys. This will allow short- and... descriptive analysis of how States designed and implemented PREP programs. The study will use multiple methods... ``Design Survey'', will focus on how states designed programs, and the second round of interviews, known as...

The theory of active involvement: processes underlying interventions that engage adolescents in message planning and/or production.

PubMed

Greene, Kathryn

2013-01-01

Adolescence is a time of increased risk taking, and recent intervention strategies have included adolescents planning or producing antirisk messages for their peers. Although these projects may generate enthusiasm, we know little about message planning or production as a strategy for changing adolescent decision-making and behavior. This article articulates the Theory of Active Involvement (TAI) to describe and explain the processes through which these active involvement interventions influence adolescents. TAI is based on social cognitive theory's notion of self-regulation and examines multiple perspective taking and activating the self-reflection processes. The theory specifically describes the process of cognitive changes experienced by participants in active involvement interventions. The sequence is conceptualized as starting when engagement with the intervention (arousal and involvement) produces skill and knowledge gains (immediate outcomes) that lead to reflection (perceived discrepancy) and then other cognitions (expectancies, norms, intentions), with the ultimate outcome being behavior change. Engaging the target audience in a process of self-reflection is conceptualized as the crucial ingredient for meaningful and sustainable change in cognitions and behavior. This article provides valuable insight into how active involvement strategies function and how to best design these interventions, particularly those targeting adolescents.

Are all sport activities equal? A systematic review of how youth psychosocial experiences vary across differing sport activities.

PubMed

Evans, M Blair; Allan, Veronica; Erickson, Karl; Martin, Luc J; Budziszewski, Ross; Côté, Jean

2017-02-01

Models of sport development often support the assumption that young athletes' psychosocial experiences differ as a result of seemingly minor variations in how their sport activities are designed (eg, participating in team or individual sport; sampling many sports or specialising at an early age). This review was conducted to systematically search sport literature and explore how the design of sport activities relates to psychosocial outcomes. Systematic search, followed by data extraction and synthesis. The Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines were applied and a coding sheet was used to extract article information and code for risk of bias. Academic databases and manual search of peer-reviewed journals. Search criteria determined eligibility primarily based on the sample (eg, ages 7 through 17 years) and study design (eg, measured psychosocial constructs). 35 studies were located and were classified within three categories: (1) sport types, (2) sport settings, and (3) individual patterns of sport involvement. These studies represented a wide range of scores when assessed for risk of bias and involved an array of psychosocial constructs, with the most prevalent investigations predicting outcomes such as youth development, self-esteem and depression by comparing (1) team or individual sport participants and (2) youth with varying amounts of sport involvement. As variations in sport activities impact youth sport experiences, it is vital for researchers to carefully describe and study these factors, while practitioners may use the current findings when designing youth sport programmes. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

Re-Designing Business Card Advertisements.

ERIC Educational Resources Information Center

Schaub, Laura

2001-01-01

Discusses ways to turn information from a business card into an advertisement to be placed in a student publication. Addresses visual interest, typography, and other design issues. Includes several sample advertisements and a classroom activity involving redesigning a business card into an advertisement. (RS)

Molecular mechanism of peroxisome proliferator-activated receptor α activation by WY14643: a new mode of ligand recognition and receptor stabilization.

PubMed

Bernardes, Amanda; Souza, Paulo C T; Muniz, João R C; Ricci, Clarisse G; Ayers, Stephen D; Parekh, Nili M; Godoy, André S; Trivella, Daniela B B; Reinach, Peter; Webb, Paul; Skaf, Munir S; Polikarpov, Igor

2013-08-23

Peroxisome proliferator-activated receptors (PPARs) are members of a superfamily of nuclear transcription factors. They are involved in mediating numerous physiological effects in humans, including glucose and lipid metabolism. PPARα ligands effectively treat dyslipidemia and have significant antiinflammatory and anti-atherosclerotic activities. These effects and their ligand-dependent activity make nuclear receptors obvious targets for drug design. Here, we present the structure of the human PPARα in complex with WY14643, a member of fibrate class of drug, and a widely used PPAR activator. The crystal structure of this complex suggests that WY14643 induces activation of PPARα in an unusual bipartite mechanism involving conventional direct helix 12 stabilization and an alternative mode that involves a second ligand in the pocket. We present structural observations, molecular dynamics and activity assays that support the importance of the second site in WY14643 action. The unique binding mode of WY14643 reveals a new pattern of nuclear receptor ligand recognition and suggests a novel basis for ligand design, offering clues for improving the binding affinity and selectivity of ligand. We show that binding of WY14643 to PPARα was associated with antiinflammatory disease in a human corneal cell model, suggesting possible applications for PPARα ligands. Copyright © 2013 Elsevier Ltd. All rights reserved.

Bringing Mathematics To Life.

ERIC Educational Resources Information Center

Castle, Marrietta; Lewis, Cathie

1996-01-01

Describes grade-appropriate weekly activities designed to appeal directly to students by giving them open-ended questions. Activities may be worked on individually, in pairs, or in small groups. This particular set of activities focuses on stories from literature involving measurement, earning money, marketing a product, and setting up a…

Discovering Geography: Teacher Created Activities for High School and Middle School.

ERIC Educational Resources Information Center

Petersen, James F., Ed.

This guide contains 20 classroom activities designed by teachers to study topics in geography with the eventual goal of aiding in the development of geographic literacy in students. The various activities involve map reading skills, climatology, current events, urban development, and community planning. Each activity presentation includes an event…

Career Activities in Science: Grades 7, 8, 9.

ERIC Educational Resources Information Center

Boise City Independent School District, ID.

The career activities guide in science, part of an Idaho State Department of Vocational Education career exploration series for grades 7, 8, and 9, is designed as supplementary material to enrich the regular curriculum. Any one activity in the guide might be used without involving any other activities. The cross-referenced index indicates grades,…

Career Activities in Social Science: Grades 7, 8, 9.

ERIC Educational Resources Information Center

Boise City Independent School District, ID.

The career activities guide in social science, part of an Idaho State Department of Vocational Education career exploration series for grades 7, 8, and 9, is designed as supplementary material to enrich the regular curriculum. Any one activity in the guide might be used without involving any other activities. The cross-referenced index indicates…

Preliminary Evidence that Self-Efficacy Predicts Physical Activity in Multiple Sclerosis

ERIC Educational Resources Information Center

Motl, Robert W.; McAuley, Edward; Doerksen, Shawna; Hu, Liang; Morris, Katherine S.

2009-01-01

Individuals with multiple sclerosis (MS) are less physically active than nondiseased people. One method for increasing physical activity levels involves the identification of factors that correlate with physical activity and that are modifiable by a well designed intervention. This study examined two types of self-efficacy as cross-sectional and…

The No Waste Anthology: A Teacher's Guide to Environmental Activities K-12.

ERIC Educational Resources Information Center

California State Dept. of Toxic Substance Control, Sacramento.

This book is designed to provide teachers with interdisciplinary, action oriented environmental activities for grades K-12 concerning the issue of waste. The activities are organized into three sections and several subsections. The first section contains 29 activities pertaining to natural resources and pollution in subsections involving needs and…

Career Activities in Mathematics: Grades 7, 8, 9.

ERIC Educational Resources Information Center

Boise City Independent School District, ID.

The career activities guide in mathematics, part of an Idaho State Department of Vocational Education career exploration series for grades 7, 8, and 9, is designed as supplementary material to enrich the regular curriculum. Any one activity in the guide might be used without involving any other activities. The cross-referenced index indicates…

Educational Game Design as Gateway for Operationalizing Computational Thinking Skills among Middle School Students

ERIC Educational Resources Information Center

Wu, Min Lun

2018-01-01

This qualitative case study reports descriptive findings of digital game-based learning involving 15 Taiwanese middle school students' use of computational thinking skills elicited through programmed activities in a game design workshop. Situated learning theory is utilized as framework to evaluate novice game designers' individual advancement in…

Metric integration architecture for product development

NASA Astrophysics Data System (ADS)

Sieger, David B.

1997-06-01

Present-day product development endeavors utilize the concurrent engineering philosophy as a logical means for incorporating a variety of viewpoints into the design of products. Since this approach provides no explicit procedural provisions, it is necessary to establish at least a mental coupling with a known design process model. The central feature of all such models is the management and transformation of information. While these models assist in structuring the design process, characterizing the basic flow of operations that are involved, they provide no guidance facilities. The significance of this feature, and the role it plays in the time required to develop products, is increasing in importance due to the inherent process dynamics, system/component complexities, and competitive forces. The methodology presented in this paper involves the use of a hierarchical system structure, discrete event system specification (DEVS), and multidimensional state variable based metrics. This approach is unique in its capability to quantify designer's actions throughout product development, provide recommendations about subsequent activity selection, and coordinate distributed activities of designers and/or design teams across all design stages. Conceptual design tool implementation results are used to demonstrate the utility of this technique in improving the incremental decision making process.

Activities.

ERIC Educational Resources Information Center

Mathematics Teacher, 1982

1982-01-01

The material presented is designed to help students explore geometric patterns involving Fibonnaci numbers and the golden ratio, and to aid in review of basic geometry skills. Worksheet masters intended for duplication are provided. Suggestions are made of possible classroom extensions to the initial activities. (MP)

Fall Activities for the Early Childhood and Special Education Classroom.

ERIC Educational Resources Information Center

Denton, Penny

Designed for teachers of early childhood or special education students, this guide contains instructions and illustrations for classroom activities for the months of September, October, and November. Most of the activities involve art projects and many incorporate teaching in other subject areas such as mathematics, language arts, science, and…

34 CFR 647.4 - What activities and services may a project provide?

Code of Federal Regulations, 2010 CFR

2010-07-01

... PROGRAM General § 647.4 What activities and services may a project provide? A McNair project may provide... activities designed to prepare participants for doctoral study. (d) Tutoring. (e) Academic counseling. (f... programs. (g) Mentoring programs involving faculty members or students at institutions of higher education...

Conservation II. Science Activities in Energy. [Student's and] Teacher's Guide.

ERIC Educational Resources Information Center

Oak Ridge Associated Universities, TN.

Designed for science students in fourth, fifth, and sixth grades, the activities in this unit illustrate principles and problems related to the conservation of energy. Eleven student activities using art, economics, arithmetic, and other skills and disciplines help teachers directly involve students in exploring scientific questions and making…

A Review: Principles of Design and Analysis of Learning Systems

ERIC Educational Resources Information Center

Durney, Carl H.

1973-01-01

Analyzes a traditional and an innovative course in terms of learning principles, involving Erickson's management methods and Gagne's learning activities. Suggests that learning systems should be designed by applying all principles rather than emphasizing one or two of them. (CC)

Designing Assessment for Mathematics

ERIC Educational Resources Information Center

Depka, Eileen

2007-01-01

Teaching mathematics in today's world requires practices and procedures integrated with performance tasks that actively involve students. In this second edition of Designing Rubrics for Mathematics, Eileen Depka clarifies the purpose of rubrics in math instruction and illustrates the relationship between assessment, rubrics, and the National…

CARE activities on superconducting RF cavities at INFN Milano

NASA Astrophysics Data System (ADS)

Bosotti, A.; Pierini, P.; Michelato, P.; Pagani, C.; Paparella, R.; Panzeri, N.; Monaco, L.; Paulon, R.; Novati, M.

2005-09-01

The SC RF group at INFN Milano-LASA is involved both in the TESLA/TTF collaboration and in the research and design activity on superconducting cavities for proton accelerators. Among these activities, some are supported by the European community within the CARE project. In the framework of the JRASRF collaboration we are developing a coaxial blade tuner for ILC (International Linear Collider) cavities, integrated with piezoelectric actuators for the compensation of the Lorenz force detuning and microphonics perturbation. Another activity, regarding the improved component design on SC technology, based on the information retrieving about the status of art on ancillaries and experience of various laboratories involved in SCRF, has started in our laboratory. Finally, in the framework of the HIPPI collaboration, we are testing two low beta superconducting cavities, built for the Italian TRASCO project, to verify the possibility to use them for pulsed operation. All these activities will be described here, together with the main results and the future perspectives.

De Novo Computational Design of Retro-Aldol Enzymes

PubMed Central

Jiang, Lin; Althoff, Eric A.; Clemente, Fernando R.; Doyle, Lindsey; Röthlisberger, Daniela; Zanghellini, Alexandre; Gallaher, Jasmine L.; Betker, Jamie L.; Tanaka, Fujie; Barbas, Carlos F.; Hilvert, Donald; Houk, Kendall N.; Stoddard, Barry L.; Baker, David

2012-01-01

The creation of enzymes capable of catalyzing any desired chemical reaction is a grand challenge for computational protein design. Using new algorithms that rely on hashing techniques to construct active sites for multistep reactions, we designed retro-aldolases that use four different catalytic motifs to catalyze the breaking of a carbon-carbon bond in a nonnatural substrate. Of the 72 designs that were experimentally characterized, 32, spanning a range of protein folds, had detectable retro-aldolase activity. Designs that used an explicit water molecule to mediate proton shuffling were significantly more successful, with rate accelerations of up to four orders of magnitude and multiple turnovers, than those involving charged side-chain networks. The atomic accuracy of the design process was confirmed by the x-ray crystal structure of active designs embedded in two protein scaffolds, both of which were nearly superimposable on the design model. PMID:18323453

Partnerships for parks and physical activity.

PubMed

Shulaker, Bianca D; Isacoff, Jennifer W; Cohen, Deborah A; Marsh, Terry; Wier, Megan; Bhatia, Rajiv

2014-01-01

Given the need for comprehensive and multidisciplinary active living interventions, this article describes an innovative partnership for park design and evaluation. The Trust for Public Land partnered with the RAND Corporation and the San Francisco Department of Public Health to generate context-sensitive active park design, establish evaluation methods, and build the framework for future collaboration. These partners worked together from 2009 to 2012 to design, renovate, and study parks in San Francisco, California. The three partnering organizations are the focus of this article. The Trust for Public Land's Parks for People-Bay Area Program raised more than $16 million to renovate three San Francisco parks, which served as the intervention for a study that initially brought the three partnering organizations together. The authors, who represent the three partners, collaborated to develop the lessons learned. This article is a description and commentary about a partnership that emphasized community involvement and rigorous evaluation. Lessons learned and elements for successful partnerships include collaborating with organizations with differing expertise, deciding upon goals initially, finding a common language, involving local communities, and recognizing the importance and appropriate role of evaluations. The model for collaboration and community involvement presented supports and encourages other organizations to use strategic, multidisciplinary partnerships and highlights the importance of evaluation.

Management and integration of engineering and construction activities: Lessons learned from the AP1000{sup R} nuclear power plant China project

DOE Office of Scientific and Technical Information (OSTI.GOV)

McCullough, M. C.; Ebeling-Koning, D.; Evans, M. C.

2012-07-01

The lessons learned during the early phase of design engineering and construction activities for the AP1000 China Project can be applied to any project involving multiple disciplines and multiple organizations. Implementation of a first-of-a-kind design to directly support construction activities utilizing resources assigned to design development and design delivery creates challenges with prioritization of activities, successful closure of issues, and communication between site organizations and the home office. To ensure successful implementation, teams were assigned and developed to directly support construction activities including prioritization of activities, site communication and ensuring closure of site emergent issues. By developing these teams, themore » organization is better suited to meet the demands of the construction schedule while continuing with design evolution of a standard plant and engineering delivery for multiple projects. For a successful project, proper resource utilization and prioritization are key for overcoming obstacles and ensuring success of the engineering organization. (authors)« less

Developing Instructional Design to Improve Mathematical Higher Order Thinking Skills of Students

NASA Astrophysics Data System (ADS)

Apino, E.; Retnawati, H.

2017-02-01

This study aimed to describe the instructional design to improve the Higher Order Thinking Skills (HOTS) of students in learning mathematics. This research is design research involving teachers and students of class X MIPA 1 MAN Yigyakarta III, Special Region of Yogyakarta, Indonesia. Data collected through focus group discussions and tests. Data analyzed by quantitative descriptive. The results showed that the instructional design developed is effective to improving students’ HOTS in learning mathematics. Instructional design developed generally include three main components: (1) involve students in the activities non-routine problem solving; (2) facilitating students to develop the ability to analyze and evaluate (critical thinking) and the ability to create (creative thinking); and (3) encourage students to construct their own knowledge.

Spreading activation in nonverbal memory networks.

PubMed

Foster, Paul S; Wakefield, Candias; Pryjmak, Scott; Roosa, Katelyn M; Branch, Kaylei K; Drago, Valeria; Harrison, David W; Ruff, Ronald

2017-09-01

Theories of spreading activation primarily involve semantic memory networks. However, the existence of separate verbal and visuospatial memory networks suggests that spreading activation may also occur in visuospatial memory networks. The purpose of the present investigation was to explore this possibility. Specifically, this study sought to create and describe the design frequency corpus and to determine whether this measure of visuospatial spreading activation was related to right hemisphere functioning and spreading activation in verbal memory networks. We used word frequencies taken from the Controlled Oral Word Association Test and design frequencies taken from the Ruff Figural Fluency Test as measures of verbal and visuospatial spreading activation, respectively. Average word and design frequencies were then correlated with measures of left and right cerebral functioning. The results indicated that a significant relationship exists between performance on a test of right posterior functioning (Block Design) and design frequency. A significant negative relationship also exists between spreading activation in semantic memory networks and design frequency. Based on our findings, the hypotheses were supported. Further research will need to be conducted to examine whether spreading activation exists in visuospatial memory networks as well as the parameters that might modulate this spreading activation, such as the influence of neurotransmitters.

Parent Involvement and the Impact on Student Achievement in Grades 2-5

ERIC Educational Resources Information Center

Thurber, Yvonne Marie

2013-01-01

This quantitative research study examined the relationship between student achievement in reading and mathematics on the STAR (Standardized Test for the Assessment of Reading and Mathematics) and parent involvement in specific character development activities. The research design was quantitative in nature and conducted in two similar elementary…

An Analysis of Active Rehearsal in Children's Memory.

ERIC Educational Resources Information Center

Stone, Barbara Prince; And Others

This paper presents a developmental study of the effects of item rehearsal on children's short term memory. Two experiments are discussed. The first, involving second and sixth grade children, concerned the relationship between item retrieval ability and rehearsal strategies in item recall. The design of the experiment involved varying the visual…

Using a Thematic Laboratory-Centered Curriculum to Teach General Chemistry

ERIC Educational Resources Information Center

Hopkins, Todd A.; Samide, Michael

2013-01-01

This article describes an approach to general chemistry that involves teaching chemical concepts in the context of two thematic laboratory modules: environmental remediation and the fate of pharmaceuticals in the environment. These modules were designed based on active-learning pedagogies and involve multiple-week projects that dictate what…

The Meteor Meter.

ERIC Educational Resources Information Center

Eggensperger, Martin B.

2000-01-01

Introduces the Meteor Scatter Project (MSP) in which high school students build an automated meteor observatory and learn to monitor meteor activity. Involves students in activities such as radio frequency survey, antenna design, antenna construction, manual meteor counts, and computer board configuration and installation. (YDS)

Gaining a Competitive Edge through Action Design Research

NASA Astrophysics Data System (ADS)

Alexa, L.; Alexa, M.; Avasilcăi, S.

2016-08-01

The current business environment is characterized by increased competition and highly innovative approach, in order to create products and services to better respond to the costumers’ needs and expectations. In this specific context, the research approaches need to be more flexible and business oriented and so, throughout the paper we have used a research method that combines design research and action research, named Action Design Research which is a research method used for generating prescriptive design knowledge through building and evaluating IT artifacts in an organizational setting [1]. Following the Action Design Research stages and principles: problem identification, building, intervention and evaluation, reflection and learning and formalization of learning, the research team has developed an online instrument used to actively involve the consumer in the product development process, in order to generate a better consumers insight regarding their needs and desires and to design and/or adjust the product accordingly. The customer engagement IT tool created and tested by using Action Design Research, E-PICUS, has been developed within the framework of the research project „E-solutions for innovation through customer pro-active involvement in value creation to increase organisational competitiveness (E-PICUS)”, PN- II-PT-PCCA-2013-4-1811, currently undergoing.

Structural design/margin assessment

NASA Technical Reports Server (NTRS)

Ryan, R. S.

1993-01-01

Determining structural design inputs and the structural margins following design completion is one of the major activities in space exploration. The end result is a statement of these margins as stability, safety factors on ultimate and yield stresses, fracture limits (fracture control), fatigue lifetime, reuse criteria, operational criteria and procedures, stability factors, deflections, clearance, handling criteria, etc. The process is normally called a load cycle and is time consuming, very complex, and involves much more than structures. The key to successful structural design is the proper implementation of the process. It depends on many factors: leadership and management of the process, adequate analysis and testing tools, data basing, communications, people skills, and training. This process and the various factors involved are discussed.

Continuous Assessment in the Oral Communication Class: Teacher Constructed Test.

ERIC Educational Resources Information Center

Nair-Venugopal, Shanta

The oral communication course for English majors at the National University of Malaysia includes testing designed by faculty and coordinated with the curriculum. This practice is based on the ideas that a teacher who has been actively involved in curriculum design is in a good position to design a test for that curriculum, and that teacher-made…

Design and Diagnosis Problem Solving with Multifunctional Technical Knowledge Bases

DTIC Science & Technology

1992-09-29

STRUCTURE METHODOLOGY Design problem solving is a complex activity involving a number of subtasks. and a number of alternative methods potentially available...Conference on Artificial Intelligence. London: The British Computer Society, pp. 621-633. Friedland, P. (1979). Knowledge-based experimental design ...Computing Milieuxl: Management of Computing and Information Systems- -ty,*m man- agement General Terms: Design . Methodology Additional Key Words and Phrases

Cross-National Analysis of Islamic Fundamentalism

DTIC Science & Technology

2016-01-20

attitudes, and was fully involved in activities concerning questionnaire design including a new experimental design in the survey, pilot testing, and...possible collaboration with the research design of the panel survey in Tunisia. • Data analysis: Analyses of religious fundamentalism, women’s dress, trust...the Event History Calendar and the best methods to ask about knowledge and experience of past events. The group designed a series of cognitive

Budget-Minded Renovation Lights Up Students' Learning.

ERIC Educational Resources Information Center

McDaniel, Craig

1998-01-01

Provides considerations for educational facility lighting designs that support student learning while controlling costs. Lighting design decision factors include the types of classroom activities involved, the importance of properly using artificial and indirect lighting, the importance of color rendering, the positioning of windows and skylights,…

The Theory of Active Involvement: Processes Underlying Interventions that Engage Adolescents in Message Planning and/or Production

PubMed Central

Greene, Kathryn

2013-01-01

Adolescence is a time of increased risk-taking and recent intervention strategies have included adolescents planning or producing anti-risk messages for their peers. Although these projects may generate enthusiasm, we know little about message planning or production as a strategy for changing adolescent decision-making and behavior. The paper articulates the Theory of Active Involvement (TAI) to describe and explain the processes through which these active involvement interventions influence adolescents. TAI is based on social cognitive theory’s notion of self-regulation and examines multiple perspective-taking and activating the self-reflection processes. The theory specifically describes the process of cognitive changes experienced by participants in active involvement interventions. The sequence is conceptualized as starting when engagement with the intervention (arousal and involvement) produces skill and knowledge gains (immediate outcomes) that lead to reflection (perceived discrepancy) and then other cognitions (expectancies, norms, intentions), with the ultimate outcome being behavior change. Engaging the target audience in a process of self-reflection is conceptualized as the crucial ingredient for meaningful and sustainable change in cognitions and behavior. This paper provides valuable insight into how active involvement strategies function and how to best design these interventions, particularly those targeting adolescents. PMID:23980581

Systematic assessment of scaffold hopping versus activity cliff formation across bioactive compound classes following a molecular hierarchy.

PubMed

Stumpfe, Dagmar; Dimova, Dilyana; Bajorath, Jürgen

2015-07-01

Scaffold hopping and activity cliff formation define opposite ends of the activity landscape feature spectrum. To rationalize these events at the level of scaffolds, active compounds involved in scaffold hopping were required to contain topologically distinct scaffolds but have only limited differences in potency, whereas compounds involved in activity cliffs were required to share the same scaffold but have large differences in potency. A systematic search was carried out for compounds involved in scaffold hopping and/or activity cliff formation. Results obtained for compound data sets covering more than 300 human targets revealed clear trends. If scaffolds represented multiple but fewer than 10 active compounds, nearly 90% of all scaffolds were exclusively involved in hopping events. With increasing compound coverage, the fraction of scaffolds involved in both scaffold hopping and activity cliff formation significantly increased to more than 50%. However, ∼40% of the scaffolds representing large numbers of active compounds continued to be exclusively involved in scaffold hopping. More than 200 scaffolds with broad target coverage were identified that consistently represented potent compounds and yielded an abundance of scaffold hops in the low-nanomolar range. These and other subsets of scaffolds we characterized are of prime interest for structure-activity relationship (SAR) exploration and compound design. Therefore, the complete scaffold classification generated in the course of our analysis is made freely available. Copyright © 2015 Elsevier Ltd. All rights reserved.

How to build institutionalization on students: a pilot experiment on a didactical design of addition and subtraction involving negative integers

NASA Astrophysics Data System (ADS)

Fuadiah, N. F.; Suryadi, D.; Turmudi

2018-05-01

This study focuses on the design of a didactical situation in addition and subtraction involving negative integers at the pilot experiment phase. As we know, negative numbers become an obstacle for students in solving problems related to them. This study aims to create a didactical design that can assist students in understanding the addition and subtraction. Another expected result in this way is that students are introduced to the characteristics of addition and subtraction of integers. The design was implemented on 32 seventh grade students in one of the classes in a junior secondary school as the pilot experiment. Learning activities were observed thoroughly including the students’ responses that emerged during the learning activities. The written documentation of the students was also used to support the analysis in the learning activities. The results of the analysis showed that this method could help the students perform a large number of integer operations that could not be done with a number line. The teacher’s support as a didactical potential contract was still needed to encourage institutionalization processes. The results of the design analysis used as the basis of the revision are expected to be implemented by the teacher in the teaching experiment.

Design, Development, Testing, and Evaluation: Human Factors Engineering

NASA Technical Reports Server (NTRS)

Adelstein, Bernard; Hobbs, Alan; OHara, John; Null, Cynthia

2006-01-01

While human-system interaction occurs in all phases of system development and operation, this chapter on Human Factors in the DDT&E for Reliable Spacecraft Systems is restricted to the elements that involve "direct contact" with spacecraft systems. Such interactions will encompass all phases of human activity during the design, fabrication, testing, operation, and maintenance phases of the spacecraft lifespan. This section will therefore consider practices that would accommodate and promote effective, safe, reliable, and robust human interaction with spacecraft systems. By restricting this chapter to what the team terms "direct contact" with the spacecraft, "remote" factors not directly involved in the development and operation of the vehicle, such as management and organizational issues, have been purposely excluded. However, the design of vehicle elements that enable and promote ground control activities such as monitoring, feedback, correction and reversal (override) of on-board human and automation process are considered as per NPR8705.2A, Section 3.3.

Using Computer Simulations to Integrate Learning.

ERIC Educational Resources Information Center

Liao, Thomas T.

1983-01-01

Describes the primary design criteria and the classroom activities involved in "The Yellow Light Problem," a minicourse on decision making in the secondary school Mathematics, Engineering and Science Achievement (MESA) program in California. Activities include lectures, discussions, science and math labs, computer labs, and development…

Bioinspired catalytic materials for energy-relevant conversions

NASA Astrophysics Data System (ADS)

Artero, Vincent

2017-09-01

The structure of active sites of enzymes involved in bioenergetic processes can inspire design of active, stable and cost-effective catalysts for renewable-energy technologies. For these materials to reach maturity, the benefits of bioinspired systems must be combined with practical technological requirements.

Sports Splash: A Handbook of Reading Activities for Use with Children. A Fun with Reading Book.

ERIC Educational Resources Information Center

Thomas, Carol H.

Intended for individuals involved in teaching children to read--parents, teachers, librarians, and reading specialists--this handbook provides activities and resources to supplement programs designed to encourage children's enjoyment of books. The reading activities presented in this handbook have been developed around a sports theme. The…

Active Participation in the Literary Encounter.

ERIC Educational Resources Information Center

Twining, James E.

A child's sense of involvement in story and desire to meaningfully experience literature must be sustained and promoted if the problem of "literacy" is to be resolved. Four activities, designed as a series of stages, can enhance the literary experience of children. The first activity is reading to children--exposing them to the language…

Personalized Strategies to Activate and Empower Patients in Health Care and Reduce Health Disparities

ERIC Educational Resources Information Center

Chen, Jie; Mullins, C. Daniel; Novak, Priscilla; Thomas, Stephen B.

2016-01-01

Designing culturally sensitive personalized interventions is essential to sustain patients' involvement in their treatment and encourage patients to take an active role in their own health and health care. We consider patient activation and empowerment as a cyclical process defined through patient accumulation of knowledge, confidence, and…

48 CFR 3452.224-71 - Notice about research activities involving human subjects.

Code of Federal Regulations, 2012 CFR

2012-10-01

... research as “a systematic investigation, including research development, testing and evaluation, designed... deliberate plan designed to develop or contribute to generalizable knowledge, it is research. Research... 48 Federal Acquisition Regulations System 7 2012-10-01 2012-10-01 false Notice about research...

48 CFR 3452.224-71 - Notice about research activities involving human subjects.

Code of Federal Regulations, 2011 CFR

2011-10-01

... research as “a systematic investigation, including research development, testing and evaluation, designed... deliberate plan designed to develop or contribute to generalizable knowledge, it is research. Research... 48 Federal Acquisition Regulations System 7 2011-10-01 2011-10-01 false Notice about research...

48 CFR 3452.224-71 - Notice about research activities involving human subjects.

Code of Federal Regulations, 2013 CFR

2013-10-01

... research as “a systematic investigation, including research development, testing and evaluation, designed... deliberate plan designed to develop or contribute to generalizable knowledge, it is research. Research... 48 Federal Acquisition Regulations System 7 2013-10-01 2012-10-01 true Notice about research...

48 CFR 3452.224-71 - Notice about research activities involving human subjects.

Code of Federal Regulations, 2014 CFR

2014-10-01

... research as “a systematic investigation, including research development, testing and evaluation, designed... deliberate plan designed to develop or contribute to generalizable knowledge, it is research. Research... 48 Federal Acquisition Regulations System 7 2014-10-01 2014-10-01 false Notice about research...

Comparison of designed and randomly generated catalysts for simple chemical reactions.

PubMed

Kipnis, Yakov; Baker, David

2012-09-01

There has been recent success in designing enzymes for simple chemical reactions using a two-step protocol. In the first step, a geometric matching algorithm is used to identify naturally occurring protein scaffolds at which predefined idealized active sites can be realized. In the second step, the residues surrounding the transition state model are optimized to increase transition state binding affinity and to bolster the primary catalytic side chains. To improve the design methodology, we investigated how the set of solutions identified by the design calculations relate to the overall set of solutions for two different chemical reactions. Using a TIM barrel scaffold in which catalytically active Kemp eliminase and retroaldolase designs were obtained previously, we carried out activity screens of random libraries made to be compositionally similar to active designs. A small number of active catalysts were found in screens of 10³ variants for each of the two reactions, which differ from the computational designs in that they reuse charged residues already present in the native scaffold. The results suggest that computational design considerably increases the frequency of catalyst generation for active sites involving newly introduced catalytic residues, highlighting the importance of interaction cooperativity in enzyme active sites. Copyright © 2012 The Protein Society.

Human-Robot Interface: Issues in Operator Performance, Interface Design, and Technologies

DTIC Science & Technology

2006-07-01

and the use of lightweight portable robotic sensor platforms. 5 robotics has reached a point where some generalities of HRI transcend specific...displays with control devices such as joysticks, wheels, and pedals (Kamsickas, 2003). Typical control stations include panels displaying (a) sensor ...tasks that do not involve mobility and usually involve camera control or data fusion from sensors Active search: Search tasks that involve mobility

Team Up at Home. Team Nutrition Activity Booklet. Fun Nutrition Activities for the Family.

ERIC Educational Resources Information Center

Food and Consumer Service (USDA), Washington, DC.

This guide booklet helps parents teach their children about healthy nutrition at home. It is part of the U.S. Department of Agriculture's Team Nutrition, which is designed to improve the health and education of children and which actively involves children and their families in nutrition education activities in the school, community, and home. The…

"A Big Door Opened for Us": Parents' Perceptions of Comprehensive Preschool

ERIC Educational Resources Information Center

DeMulder, Elizabeth K.; Stribling, Stacia M.

2012-01-01

This qualitative research study was designed to explore the perceptions of parents with low income regarding the effects of involvement in a comprehensive preschool program on their children's development and on the families' quality of life. A purposeful sample of parents who became actively involved in the preschool community was interviewed…

Antiviral drug research proposal activity.

PubMed

Injaian, Lisa; Smith, Ann C; Shipley, Jennifer German; Marbach-Ad, Gili; Fredericksen, Brenda

2011-01-01

The development of antiviral drugs provides an excellent example of how basic and clinical research must be used together in order to achieve the final goal of treating disease. A Research Oriented Learning Activity was designed to help students to better understand how basic and clinical research can be combined toward a common goal. Through this project students gained a better understanding of the process of scientific research and increased their information literacy in the field of virology. The students worked as teams to research the many aspects involved in the antiviral drug design process, with each student becoming an "expert" in one aspect of the project. The Antiviral Drug Research Proposal (ADRP) culminated with students presenting their proposals to their peers and local virologists in a poster session. Assessment data showed increased student awareness and knowledge of the research process and the steps involved in the development of antiviral drugs as a result of this activity.

Antiviral Drug Research Proposal Activity †

PubMed Central

Injaian, Lisa; Smith, Ann C.; Shipley, Jennifer German; Marbach-Ad, Gili; Fredericksen, Brenda

2011-01-01

The development of antiviral drugs provides an excellent example of how basic and clinical research must be used together in order to achieve the final goal of treating disease. A Research Oriented Learning Activity was designed to help students to better understand how basic and clinical research can be combined toward a common goal. Through this project students gained a better understanding of the process of scientific research and increased their information literacy in the field of virology. The students worked as teams to research the many aspects involved in the antiviral drug design process, with each student becoming an “expert” in one aspect of the project. The Antiviral Drug Research Proposal (ADRP) culminated with students presenting their proposals to their peers and local virologists in a poster session. Assessment data showed increased student awareness and knowledge of the research process and the steps involved in the development of antiviral drugs as a result of this activity. PMID:23653735

Does Using a Chair Backrest or Reducing Seated Hip Flexion Influence Trunk Muscle Activity and Discomfort? A Systematic Review.

PubMed

Curran, Máire; O'Sullivan, Leonard; O'Sullivan, Peter; Dankaerts, Wim; O'Sullivan, Kieran

2015-11-01

This paper systematically reviews the effect of chair backrests and reducing seated hip flexion on low back discomfort (LBD) and trunk muscle activation. Prolonged sitting commonly exacerbates low back pain (LBP). Several modifications to seated posture and chair design have been recommended, including using chairs with backrests and chairs that reduce hip flexion. Electronic databases were searched by two independent assessors. Part 1 of this review includes 26 studies comparing the effect of sitting with at least two different hip angles. In Part 2, seven studies that compared the effect of sitting with and without a backrest were eligible. Study quality was assessed using the PEDro scale. Significant confounding variables and a relatively small number of randomized controlled trials (RCTs) involving people with LBP complicates analysis of the results. There was moderate evidence that chair backrests reduce paraspinal muscle activation, and limited evidence that chair backrests reduce LBD. There was no evidence that chairs involving less hip flexion reduce LBP or LBD, or consistently alter trunk muscle activation. However, participants in several studies subjectively preferred the modified chairs involving less hip flexion. The limited evidence to support the use of chairs involving less seated hip flexion, or the effect of a backrest, is consistent with the limited evidence that other isolated chair design features can reduce LBP. LBP management is likely to require consideration of several factors in addition to sitting position. Larger RCTs involving people with LBP are required. © 2015, Human Factors and Ergonomics Society.

Teaching Research Methodology through Active Learning

ERIC Educational Resources Information Center

Lundahl, Brad W.

2008-01-01

To complement traditional learning activities in a masters-level research methodology course, social work students worked on a formal research project which involved: designing the study, constructing measures, selecting a sampling strategy, collecting data, reducing and analyzing data, and finally interpreting and communicating the results. The…

A Problem Solving Active-Learning Course in Pharmacotherapy.

ERIC Educational Resources Information Center

Delafuente, Jeffrey C.; And Others

1994-01-01

A third-year pharmacology course in a doctoral pharmacy program that is case based and intended for a large class is described. Aspects discussed include learning objectives, course organization, classroom activities, case selection and design, faculty involvement, grading, and areas identified for improvement. (MSE)

A Role-Play to Illustrate the Energy Changes Occurring in an Exothermic Reaction.

ERIC Educational Resources Information Center

Tyas, Toby; Cabot, John

1999-01-01

Describes a role-play activity designed to help students understand the energy changes involved in an exothermic reaction by modeling the concepts of bond-breaking takes in energy, activation energy, temperature rise, and bond breaking gives out energy. (WRM)

23 CFR 771.113 - Timing of Administration activities.

Code of Federal Regulations, 2010 CFR

2010-04-01

... a finding of no significant impact (FONSI) or a record of decision (ROD) and comply with other related environmental laws and regulations to the maximum extent possible during the NEPA process. This... involvement. However, final design activities, property acquisition, purchase of construction materials or...

United States History Simulations: 1787-1868: Constitution Convention, Missouri Compromise, Treaty of Guadalupe Hidalgo, The Compromise of 1850, The Kansas/Nebraska Act, Southern Secession from the Union, and the Impeachment and Trial of Andrew Johnson. ETC Simulations Number Two.

ERIC Educational Resources Information Center

Hostrop, Richard W.

This book presents simulation activities for significant events in U.S. history from 1787-1868. Intended for student involvement, the simulations require student research and practice in order to carry out the designated roles. The simulation and role play serve to involve the students actively in their learning, using both the affective and…

Cooperative dual catalysis: application to the highly enantioselective conjugate cyanation of unsaturated imides.

PubMed

Sammis, Glenn M; Danjo, Hiroshi; Jacobsen, Eric N

2004-08-18

Cooperative heterobimetallic catalysis was used as a design principle to achieve a highly reactive system for the enantioselective conjugate addition of cyanide to alpha,beta-unsaturated imides. A dual-catalyst pathway involving chiral (salen)Al complex 1b and chiral (pybox)Er complex 4b provides measurable improvements in rates and enantioselectivities relative to single-catalyst systems. Mechanistic studies point to a cooperative bimetallic mechanism involving activation of the imide by the Al complex and activation of cyanide by the Er complex.

Curriculum Design of a Flipped Classroom to Enhance Haematology Learning

ERIC Educational Resources Information Center

Porcaro, Pauline A.; Jackson, Denise E.; McLaughlin, Patricia M.; O'Malley, Cindy J.

2016-01-01

A common trend in higher education is the "flipped" classroom, which facilitates active learning during class. The flipped approach to teaching was instituted in a haematology "major" class and the students' attitudes and preferences for the teaching materials were surveyed. The curriculum design was explicit and involved four…

Five Principles for MOOC Design: With a Case Study

ERIC Educational Resources Information Center

Drake, John R.; O'Hara, Margaret; Seeman, Elaine

2015-01-01

New web technologies have enabled online education to take on a massive scale, prompting many universities to create massively open online courses (MOOCs) that take advantage of these technologies in a seemingly effortless manner. Designing a MOOC, however, is anything but trivial. It involves developing content, learning activities, and…

Applying Learning Theories and Instructional Design Models for Effective Instruction

ERIC Educational Resources Information Center

Khalil, Mohammed K.; Elkhider, Ihsan A.

2016-01-01

Faculty members in higher education are involved in many instructional design activities without formal training in learning theories and the science of instruction. Learning theories provide the foundation for the selection of instructional strategies and allow for reliable prediction of their effectiveness. To achieve effective learning…

Learning from "Escuela": Documentary Film as a Context for Teacher Learning

ERIC Educational Resources Information Center

Khasnabis, Debi; Goldin, Simona

2016-01-01

This article reports on the design of a teacher education activity that involves the documentary film, "Escuela," which was produced by Hannah Weyer. We describe this instructional design, highlighting how documentary film can be used strategically to create opportunities for teacher candidates to approximate the work of culturally…

Service Learning: An Auditing Project Study

ERIC Educational Resources Information Center

Laing, Gregory Kenneth

2013-01-01

There is a growing demand in higher education for universities to introduce teaching methods that achieve the learning outcomes of vocational education. The need for vocational educational outcomes was met in this study involving a service learning activity designed to provide basic professional auditing competencies. The details of the design and…

A Model for the Redesign of Training Materials for the Nuclear Power Industry.

ERIC Educational Resources Information Center

Gredler, Margaret Bell

1986-01-01

Presents consultant/staff model for training program redesign and discusses activities involved: interpretation of Instructional System Design (ISD) model concepts into plans in trainer's content area and sequenced sets of content-appropriate verbs for objectives; presenting training sessions on design issues; and holding individual conference…

Establishing a "Centre for Engineering Experimentation and Design Simulation": A Step towards Restructuring Engineering Education in India

ERIC Educational Resources Information Center

Venkateswarlu, P.

2017-01-01

Reforms in undergraduate engineering curriculum to produce engineers with entrepreneurial skills should address real-world problems relevant to industry and society with active industry support. Technology-assisted, hands-on projects involving experimentation, design simulation and prototyping will transform graduates into professionals with…

Photography activities for developing students’ spatial orientation and spatial visualization

NASA Astrophysics Data System (ADS)

Hendroanto, Aan; van Galen, Frans; van Eerde, D.; Prahmana, R. C. I.; Setyawan, F.; Istiandaru, A.

2017-12-01

Spatial orientation and spatial visualization are the foundation of students’ spatial ability. They assist students’ performance in learning mathematics, especially geometry. Considering its importance, the present study aims to design activities to help young learners developing their spatial orientation and spatial visualization ability. Photography activity was chosen as the context of the activity to guide and support the students. This is a design research study consisting of three phases: 1) preparation and designing 2) teaching experiment, and 3) retrospective analysis. The data is collected by tests and interview and qualitatively analyzed. We developed two photography activities to be tested. In the teaching experiments, 30 students of SD Laboratorium UNESA, Surabaya were involved. The results showed that the activities supported the development of students’ spatial orientation and spatial visualization indicated by students’ learning progresses, answers, and strategies when they solved the problems in the activities.

28 CFR 544.32 - Goals.

Code of Federal Regulations, 2013 CFR

2013-07-01

... activities are designed to attract inmate participation regardless of ethnic, racial, age, or sex difference, or handicap considerations, and to enhance the potential for post-release involvement. (b) Leisure...

28 CFR 544.32 - Goals.

Code of Federal Regulations, 2011 CFR

2011-07-01

... activities are designed to attract inmate participation regardless of ethnic, racial, age, or sex difference, or handicap considerations, and to enhance the potential for post-release involvement. (b) Leisure...

28 CFR 544.32 - Goals.

Code of Federal Regulations, 2014 CFR

2014-07-01

... activities are designed to attract inmate participation regardless of ethnic, racial, age, or sex difference, or handicap considerations, and to enhance the potential for post-release involvement. (b) Leisure...

28 CFR 544.32 - Goals.

Code of Federal Regulations, 2010 CFR

2010-07-01

... activities are designed to attract inmate participation regardless of ethnic, racial, age, or sex difference, or handicap considerations, and to enhance the potential for post-release involvement. (b) Leisure...

28 CFR 544.32 - Goals.

Code of Federal Regulations, 2012 CFR

2012-07-01

... activities are designed to attract inmate participation regardless of ethnic, racial, age, or sex difference, or handicap considerations, and to enhance the potential for post-release involvement. (b) Leisure...

Stakeholder involvement in the design of a patient-centered comparative effectiveness trial of the "On the Move" group exercise program in community-dwelling older adults.

PubMed

Brach, Jennifer S; Perera, Subashan; Gilmore, Sandra; VanSwearingen, Jessie M; Brodine, Deborah; Wert, David; Nadkarni, Neelesh K; Ricci, Edmund

2016-09-01

Group exercise programs for older adults often exclude the timing and coordination of movement. Stakeholder involvement in the research process is strongly encouraged and improves the relevance and adoption of findings. We describe stakeholder involvement in the design of a clinical trial of a group-based exercise program that incorporates timing and coordination of movement into the exercises. The study was a cluster randomized, single-blind intervention trial to compare the effects on function, disability and mobility of a standard group exercise program and the "On the Move" group exercise program in older adults residing in independent living facilities and senior apartment buildings, and attending community centers. Exercise classes were twice weekly for 12weeks delivered by study exercise leaders and facility activity staff personnel. The primary outcomes function, disability and mobility were assessed at baseline and post-intervention. Function and disability were assessed using the Late Life Function and Disability Instrument, and mobility using the Six-Minute Walk Test and gait speed. Patient and provider stakeholders had significant input into the study aims, design, sample, intervention, outcomes and operational considerations. A community-based exercise program to improve walking can be developed to address both investigator identified missing components in current exercise to improve walking and stakeholder defined needs and interest for the activity program. Involvement of stakeholders substantially improves the relevance of research questions, increases the transparency of research activities and may accelerate the adoption of research into practice. Copyright © 2016 Elsevier Inc. All rights reserved.

Stakeholder involvement in the design of a patient-centered comparative effectiveness trial of the “On the Move” group exercise program in community-dwelling older adults

PubMed Central

Brach, Jennifer S.; Perera, Subashan; Gilmore, Sandra; VanSwearingen, Jessie M.; Brodine, Deborah; Wert, David; Nadkarni, Neelesh K.; Ricci, Edmund

2016-01-01

Background Group exercise programs for older adults often exclude the timing and coordination of movement. Stakeholder involvement in the research process is strongly encouraged and improves the relevance and adoption of findings. We describe stakeholder involvement in the design of a clinical trial of a group-based exercise program that incorporates timing and coordination of movement into the exercises. Methods The study was a cluster randomized, single-blind intervention trial to compare the effects on function, disability and mobility of a standard group exercise program and the “On the Move” group exercise program in older adults residing in independent living facilities and senior apartment buildings, and attending community centers. Exercise classes were twice weekly for 12 weeks delivered by study exercise leaders and facility activity staff personnel. Outcomes The primary outcomes function, disability and mobility were assessed at baseline and post-intervention. Function and disability were assessed using the Late Life Function and Disability Instrument, and mobility using the Six-Minute Walk Test and gait speed. Stakeholders Patient and provider stakeholders had significant input into the study aims, design, sample, intervention, outcomes and operational considerations. Summary A community-based exercise program to improve walking can be developed to address both investigator identified missing components in current exercise to improve walking and stakeholder defined needs and interest for the activity program. Involvement of stakeholders substantially improves the relevance of research questions, increases the transparency of research activities and may accelerate the adoption of research into practice. PMID:27521806

An Inquiry-Based Contextual Approach as the Primary Mode of Learning Science with Microcomputer-Based Laboratory Technology

ERIC Educational Resources Information Center

Espinoza, Fernando; Quarless, Duncan

2010-01-01

Science instruction can be designed to be laboratory-data driven. We report on an investigation of the use of thematic inquiry-based tasks with active incorporation of mathematics, science, and microcomputer-based laboratory technology in standards-correlated activities that enhanced learning experiences. Activities involved students in two major…

Public Awareness Ideas and Strategies for Professional Counselors. For Use During Counseling Awareness Month and throughout the Year.

ERIC Educational Resources Information Center

American Counseling Association, Office of Public Policy and Information, Alexandria, VA.

This guide encourages counselors to actively celebrate Counseling Awareness Month. It was designed to simplify planning and publicizing activities for counselors involved with Counseling Awareness Month. It includes information about activities ranging from the simple, such as wearing a Counseling Awareness Month T-shirt, to the ambitious, such as…

Designing Efficient Self-Diagnosis Activities in the Physics Classroom

ERIC Educational Resources Information Center

Safadi, Rafi'

2017-01-01

Self-diagnosis (SD) activities require students to self-diagnose their solutions to problems that they solved on their own. This involves identifying where they went wrong and then explaining the nature of their errors--why they went wrong--aided by some form of support. Worked examples (WEs) are often used to support students in SD activities. A…

An Evaluation of Five Critical/Creative Thinking Strategies for Secondary Science Students.

ERIC Educational Resources Information Center

Zielinski, Edward J.; Sarachine, D. Michael

1994-01-01

Critical and creative thinking lessons were designed and presented to 20 biology students in a rural high school. Student attitudes toward critical thinking activities improved significantly after activities involving experimentation, discrepant events, student questioning, ethical dilemmas, and divergent and critical thinking. Includes examples…

Readiness for Solving Story Problems.

ERIC Educational Resources Information Center

Dunlap, William F.

1982-01-01

Readiness activities are described which are designed to help learning disabled (LD) students learn to perform computations in story problems. Activities proceed from concrete objects to numbers and involve the students in devising story problems. The language experience approach is incorporated with the enactive, iconic, and symbolic levels of…

Say Cheese, Please!

ERIC Educational Resources Information Center

Martell, Mary Kathryn

2001-01-01

Presents five cross-curricular activities involving student snapshots that are designed to keep students motivated. Activities include creating a class book with teacher and student photographs, making photo magnets using frozen juice can tops, developing a first-week word wall with students' names and photographs, and creating a post office with…

Trash Ecology

ERIC Educational Resources Information Center

Lind, Georgia J.

2004-01-01

A hands on activity involving density, frequency and biomass using transects, quadrats and a local good deed by cleaning up the neighborhood while practicing important techniques in ecology is detailed. The activity is designed for KCC-STEP, whose primary goal is to expand the scientific knowledge and research experiences of their students, who…

Interactive Engagement in the Large Lecture Environment

NASA Astrophysics Data System (ADS)

Dubson, Michael

Watching a great physics lecture is like watching a great piano performance. It is can be inspiring, and it can give you insights, but it doesn't teach you to play piano. Students don't learn physics by watching expert professors perform at the board; they can only learn by practicing it themselves. Learning physics involves high-level thinking like formulating problem-solving strategies or explaining concepts to other humans. Learning is always messy, involving struggle, trial-and-error, and paradigm shifts. That learning struggle cannot be overcome with a more eloquent lecture; it can only be surmounted with prolonged, determined, active engagement by the student. I will demonstrate some techniques of active engagement, including clicker questions and in-class activities, which are designed to activate the student's higher-level thinking, get them actively involved in their learning, and start them on the path of productive struggle. These techniques are scalable; they work in classrooms with 30 or 300 students. This talk about audience participation will involve audience participation, so please put down your phone and be ready for a challenge.

How can students contribute? A qualitative study of active student involvement in development of technological learning material for clinical skills training.

PubMed

Haraldseid, Cecilie; Friberg, Febe; Aase, Karina

2016-01-01

Policy initiatives and an increasing amount of the literature within higher education both call for students to become more involved in creating their own learning. However, there is a lack of studies in undergraduate nursing education that actively involve students in developing such learning material with descriptions of the students' roles in these interactive processes. Explorative qualitative study, using data from focus group interviews, field notes and student notes. The data has been subjected to qualitative content analysis. Active student involvement through an iterative process identified five different learning needs that are especially important to the students: clarification of learning expectations, help to recognize the bigger picture, stimulation of interaction, creation of structure, and receiving context- specific content. The iterative process involvement of students during the development of new technological learning material will enhance the identification of important learning needs for students. The use of student and teacher knowledge through an adapted co-design process is the most optimal level of that involvement.

Art Is for Everyone.

ERIC Educational Resources Information Center

Ensign, Arselia, Ed.

1994-01-01

This pamphlet examines what art can mean to a child with a disability and offers "how-to's" for involving students in the creation of art. It emphasizes that the outcome of an art activity can be more than just the finished piece of work and that emphasis should be placed on involvement with the materials rather than on design or abstract concepts…

Ergonomics principles to design clothing work for electrical workers in Colombia.

PubMed

Castillo, Juan; Cubillos, A

2012-01-01

The recent development of the Colombian legislation, have been identified the need to develop protective clothing to work according to specifications from the work done and in compliance with international standards. These involve the development and design of new strategies and measures for work clothing design. In this study we analyzes the activities of the workers in the electrical sector, the method analyzes the risks activity data in various activities, that activities include power generation plants, local facilities, industrial facilities and maintenance of urban and rural networks. The analyses method is focused on ergonomic approach, risk analysis is done, we evaluate the role of security expert and we use a design algorithm developed for this purpose. The result of this study is the identification of constraints and variables that contribute to the development of a model of analysis that leads to the development the work protective clothes.

Agriculture: Land Use

EPA Pesticide Factsheets

Land Use and agriculture. Information about land use restrictions and incentive programs.Agricultural operations sometimes involve activities regulated by laws designed to protect water supplies, threatened or endangered plants and animals, or wetlands.

Active learning of introductory optics: real-time physics labs, interactive lecture demonstrations and magic

NASA Astrophysics Data System (ADS)

Sokoloff, David R.

2005-10-01

Widespread physics education research has shown that most introductory physics students have difficulty learning essential optics concepts - even in the best of traditional courses, and that well-designed active learning approaches can remedy this problem. This mini-workshop and the associated poster session will provide direct experience with methods for promoting students' active involvement in the learning process in lecture and laboratory. Participants will have hands-on experience with activities from RealTime Physics labs and Interactive Lecture Demonstrations - a learning strategy for large (and small) lectures, including specially designed Optics Magic Tricks. The poster will provide more details on these highly effective curricula.

Supporting public involvement in research design and grant development: a case study of a public involvement award scheme managed by a National Institute for Health Research (NIHR) Research Design Service (RDS).

PubMed

Boote, Jonathan D; Twiddy, Maureen; Baird, Wendy; Birks, Yvonne; Clarke, Clare; Beever, Daniel

2015-10-01

It is good practice for the public to be involved in developing health research. Resources should be available for researchers to fund the involvement of the public in the development of their grants. To describe a funding award scheme to support public involvement in grant development, managed by an NIHR Research Design Service (RDS). Case examples of how the award contributed to successful grant applications and findings from a recent evaluation of the scheme are presented. A case study of resource provision to support public involvement activities in one region of England. University and NHS-based researchers, and members of the public. Between 2009 and 2012, the RDS approved 45 public involvement funding awards (totalling nearly £19,000). These awards contributed to 27 submitted applications at the time of writing, of which 11 were successful (totalling over £7.5 million). The evaluation revealed difficulties encountered by some researchers when involving the public in grant development, which led to suggestions about how the scheme could be improved. This award scheme represents an efficient method of providing researchers with resources to involve the public in grant development and would appear to represent good value for money. © 2013 John Wiley & Sons Ltd.

The conception, birth, and growth of a missile umbilical system

NASA Technical Reports Server (NTRS)

Nordman, G. W.

1977-01-01

The design development was traced for the sprint 2 and improved sprint 2 missile system (ISMS) umbilical system. The unique system requirements, umbilical designs considered to meet the requirements, and the problems encountered and solutions derived during the design, and development testing of the selected systems are described. The sprint 2 development effort consisted of design, analysis, and testing activities. The ISMS effort involved the performance of an extensive trade study to determine the optimum design to meet the ISMS conditions.

What is the E.Q. (Environmental Quality) of Your School?

ERIC Educational Resources Information Center

1971

Designed for elementary school use, this manual provides teachers with numerous experiments and activities to help children understand and evaluate the surrounding environment. Activities are planned to explore many aspects of the environmental problem. Suggestions for involvement in language arts, social studies, and mathematics are included…

Enhancing Students' Problem-Solving Skills through Context-Based Learning

ERIC Educational Resources Information Center

Yu, Kuang-Chao; Fan, Szu-Chun; Lin, Kuen-Yi

2015-01-01

Problem solving is often challenging for students because they do not understand the problem-solving process (PSP). This study presents a three-stage, context-based, problem-solving, learning activity that involves watching detective films, constructing a context-simulation activity, and introducing a project design to enable students to construct…

The American Revolution: The Declaration and Beyond. [Lesson Plan].

ERIC Educational Resources Information Center

Kasper, Paula

Based on Thomas Paine's pamphlet "Common Sense," this lesson plan presents activities designed to help students understand that as the American Revolution approached, writers created highly persuasive documents calling for separation from England. The main activity in the lesson involves students in writing a persuasive essay. It includes…

Peninsula Humane Society Teacher's Packet. Secondary Level.

ERIC Educational Resources Information Center

Peninsula Humane Society, San Mateo, CA.

Activities in this teacher's packet are designed to familiarize secondary school students with the responsibilities involved in pet ownership. Teaching plans are provided for a total of 12 lessons grouped under social studies, language arts, math, and health sciences. Activities focus on pet overpopulation, expressions of social responses in…

Physical Activity Based Professional Development for Teachers: The Importance of Whole School Involvement

ERIC Educational Resources Information Center

Till, Jude; Ferkins, Lesley; Handcock, Phil

2011-01-01

Objective: This study sought to investigate teachers' perceptions of a physical activity-related professional development intervention. Design: Interview-based qualitative approach founded on the interpretive paradigm. Setting: Purposive selection of one high-rated independent, and one low-rated public primary school from Auckland, New Zealand.…

Young Children's Metarepresentational Competence in Data Modelling

ERIC Educational Resources Information Center

English, Lyn

2012-01-01

This paper reports findings from an activity implemented in the final year of a 3-year longitudinal study of data modelling across grades 1-3. The activity engaged children in designing, implementing, and analysing a survey about their new playground. Data modelling involves investigations of meaningful phenomena, deciding what is worthy of…

Ecosystem Matters: Activity and Resource Guide for Environmental Educators.

ERIC Educational Resources Information Center

Adams, Mary; And Others

An ecological approach involved making conscious decisions which result in actions that responsibly contribute to the long-term stewardship of natural resources. This activity and resource guide was designed for use by both educators and resource managers to supplement existing courses and programs concerning ecological matters. These…

Alternatives for jet engine control

NASA Technical Reports Server (NTRS)

Sain, M. K.

1983-01-01

The technical progress of researches on alternatives for jet engine control, is reported. The principal new activities involved the initial testing of an input design method for choosing the inputs to a non-linear system to aid the approximation of its tensor parameters, and the beginning of order reduction studies designed to remove unnecessary monomials from tensor models.

40 CFR 300.515 - Requirements for state involvement in remedial and enforcement response.

Code of Federal Regulations, 2012 CFR

2012-07-01

... not limited to, remedial investigations, feasibility studies, and remedial designs, the state agency... later than the early stages of the comparative analysis described in § 300.430(e)(9), such that... separate phase or activity, for supervising the remedial design and construction of the entire remedy. (2...

40 CFR 300.515 - Requirements for state involvement in remedial and enforcement response.

Code of Federal Regulations, 2010 CFR

2010-07-01

... not limited to, remedial investigations, feasibility studies, and remedial designs, the state agency... later than the early stages of the comparative analysis described in § 300.430(e)(9), such that... separate phase or activity, for supervising the remedial design and construction of the entire remedy. (2...

40 CFR 300.515 - Requirements for state involvement in remedial and enforcement response.

Code of Federal Regulations, 2014 CFR

2014-07-01

... not limited to, remedial investigations, feasibility studies, and remedial designs, the state agency... later than the early stages of the comparative analysis described in § 300.430(e)(9), such that... separate phase or activity, for supervising the remedial design and construction of the entire remedy. (2...

40 CFR 300.515 - Requirements for state involvement in remedial and enforcement response.

Code of Federal Regulations, 2013 CFR

2013-07-01

... not limited to, remedial investigations, feasibility studies, and remedial designs, the state agency... later than the early stages of the comparative analysis described in § 300.430(e)(9), such that... separate phase or activity, for supervising the remedial design and construction of the entire remedy. (2...

40 CFR 300.515 - Requirements for state involvement in remedial and enforcement response.

Code of Federal Regulations, 2011 CFR

2011-07-01

... not limited to, remedial investigations, feasibility studies, and remedial designs, the state agency... later than the early stages of the comparative analysis described in § 300.430(e)(9), such that... separate phase or activity, for supervising the remedial design and construction of the entire remedy. (2...

Spatial Cognition Support for Exploring the Design Mechanics of Building Structures

ERIC Educational Resources Information Center

Rudy, Margit; Hauck, Richard

2008-01-01

A web-based tool for visualizing the simulated structural behavior of building models was developed to support the teaching of structural design to architecture and engineering students by activating their spatial cognition capabilities. The main didactic issues involved establishing a consistent and complete three-dimensional vocabulary (3D)…

Evaluation Design: 1981-82 State Compensatory Education. Publication No. 81.20.

ERIC Educational Resources Information Center

Mangino, Evangelina; And Others

The evaluation of the 1981-82 State Compensatory Education (SCE) program, as implemented in the Austin Independent School District, will involve the following major activities: production of an Evaluation Design based on input received from key SCE personnel; production of a Final Report and a Technical Report which present information and…

Hypothesis-Driven Laboratories: An Innovative Way to Foster Learning in Physiology Laboratory Courses

ERIC Educational Resources Information Center

Steury, Michael D.; Poteracki, James M.; Kelly, Kevin L.; Rennhack, Jonathan; Wehrwein, Erica A.

2016-01-01

Physiology instructors often are faced with the challenge of providing informative and educationally stimulating laboratories while trying to design them in such a way that encourages students to be actively involved in their own learning. With many laboratory experiments designed with simplicity and efficiency as the primary focus, it is…

Technology to Support Teachers Using Evidence from Student Work to Customize Technology-Enhanced Inquiry Units

ERIC Educational Resources Information Center

Matuk, Camillia F.; Linn, Marcia C.; Eylon, Bat-Sheva

2015-01-01

Teachers' involvement in curriculum design is essential for sustaining the relevance of technology-enhanced learning materials. Customizing--making small adjustments to tailor given materials to particular situations and settings--is one design activity in which busy teachers can feasibly engage. Research indicates that customizations based…

Blended Course Design: Where's the Pedagogy?

ERIC Educational Resources Information Center

McGee, Patricia

2014-01-01

Blended or hybrid course design is generally considered to involve a combination of online and classroom activities. However defining blended courses solely based on delivery mode suggests there is nothing more to a blended course than where students meet and how they use technology. Ultimately there is a risk that blended courses defined in this…

MALL in the Wild: Learners' Designs for Scaffolding Vocabulary Learning Trajectories

ERIC Educational Resources Information Center

Underwood, Joshua; Luckin, Rosemary; Winters, Niall

2014-01-01

This study aims to inform the design of mobile apps for vocabulary learning. Learning vocabulary involves developing, connecting, and sustaining various types of knowledge and skills. Learners do not typically acquire these all at once, but rather over the course of distinct episodes of activity. Yet, little is known about learning experience…

Development of a Semester-Long, Inquiry-Based Laboratory Course in Upper-Level Biochemistry and Molecular Biology

ERIC Educational Resources Information Center

Murthy, Pushpalatha P. N.; Thompson, Martin; Hungwe, Kedmon

2014-01-01

A semester-long laboratory course was designed and implemented to familiarize students with modern biochemistry and molecular biology techniques. The designed format involved active student participation, evaluation of data, and critical thinking, and guided students to become independent researchers. The first part of the course focused on…

Design, randomization and methodology of the TriAtiva Program to reduce obesity in school children in Southern Brazil.

PubMed

Friedrich, Roberta R; Caetano, Lisandrea C; Schiffner, Mariana D; Wagner, Mário B; Schuch, Ilaine

2015-04-11

The prevalence of child obesity in Brazil has increased rapidly in recent decades. There is, therefore, an urgent need to develop effective strategies to prevent and control child obesity. In light of these considerations, an intervention program with a focus on nutrition education and physical activity was developed for to prevent and control obesity in schools. The intervention was called the TriAtiva Program: Education, Nutrition and Physical Activity. This article describes the design, randomization and method used to evaluate the TriAtiva program. This randomized controlled cluster trial was performed in 12 municipal schools in the city of Porto Alegre/RS (six schools in the intervention group and six control schools) which offered first- through fourth grade, during one school year. The TriAtiva Program was implemented through educational activities related to healthy eating and physical activity, creating an environment which promoted student health while involving the school community and student families. The primary outcome of the present study was body mass, while its secondary outcomes were waist circumference, percent body fat, blood pressure and behavioural variables such as eating habits and physical activity levels, as well as the prevalence, incidence and remission rates of obesity. The intervention was developed based on a comprehensive review of controlled trials of similar design. The TriAtiva Program: Education, Nutrition and Physical Activity was the first study in Southern Brazil to use a randomized controlled design to evaluate an intervention involving both nutrition education and physical activity in schools. Our results will contribute to the development of future interventions aimed at preventing and controlling child obesity in schools, especially in Brazil. Brazilian Clinical Trials Registry (REBEC) number RBR2xx2z4.

78 FR 76151 - Agency Information Collection Activities: Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-16

... better allocate resources. Methodological tests will continue to be designed to examine the feasibility... reporting. Research will involve focus groups, cognitive laboratory testing, customer satisfaction surveys...

A computer program for the design of optimum catalytic monoliths for CO2 lasers

NASA Technical Reports Server (NTRS)

Guinn, K.; Goldblum, S.; Noskowski, E.; Herz, R.

1990-01-01

Pulsed CO2 lasers have many applications in aeronautics, space research, weather monitoring and other areas. Full exploitation of the potential of these lasers is hampered by the dissociation of CO2 that occurs during laser operation. The development of closed-cycle CO2 lasers requires active CO-O2 recombination (CO oxidation) catalysts and design methods for implementation of catalysts inside lasers. The performance criteria and constraints involved in the design of catalyst configurations for use in a closed-cycle laser are discussed, and several design studies performed with a computerized design program that was written are presented. Trade-offs between catalyst activity and dimensions, flow channel dimensions, pressure drop, O2 conversion and other variables are discussed.

Analysis of multiple activity manual materials handling tasks using A Guide to Manual Materials Handling.

PubMed

Mital, A

1999-01-01

Manual handling of materials continues to be a hazardous activity, leading to a very significant number of severe overexertion injuries. Designing jobs that are within the physical capabilities of workers is one approach ergonomists have adopted to redress this problem. As a result, several job design procedures have been developed over the years. However, these procedures are limited to designing or evaluating only pure lifting jobs or only the lifting aspect of a materials handling job. This paper describes a general procedure that may be used to design or analyse materials handling jobs that involve several different kinds of activities (e.g. lifting, lowering, carrying, pushing, etc). The job design/analysis procedure utilizes an elemental approach (breaking the job into elements) and relies on databases provided in A Guide to Manual Materials Handling to compute associated risk factors. The use of the procedure is demonstrated with the help of two case studies.

Developing Science Communication in Africa: Undergraduate and Graduate Students should be Trained and Actively Involved in Outreach Activity Development and Implementation.

PubMed

Karikari, Thomas K; Yawson, Nat Ato; Quansah, Emmanuel

2016-01-01

Despite recent improvements in scientific research output from Africa, public understanding of science in many parts of the continent remains low. Science communication there is faced with challenges such as (i) lack of interest among some scientists, (ii) low availability of training programs for scientists, (iii) low literacy rates among the public, and (iv) multiplicity of languages. To address these challenges, new ways of training and motivating scientists to dialogue with non-scientists are essential. Developing communication skills early in researchers' scientific career would be a good way to enhance their public engagement abilities. Therefore, a potentially effective means to develop science communication in Africa would be to actively involve trainee scientists (i.e., undergraduate and graduate students) in outreach activity development and delivery. These students are often enthusiastic about science, eager to develop their teaching and communication skills, and can be good mentors to younger students. Involving them in all aspects of outreach activity is, therefore, likely to be a productive implementation strategy. However, science communication training specifically for students and the involvement of these students in outreach activity design and delivery are lacking in Africa. Here, we argue that improving the training and involvement of budding scientists in science communication activities would be a good way to bridge the wide gap between scientists and the African public.

Wiki-Mediated Activities in Higher Education: Evidence-Based Analysis of Learning Effectiveness across Three Studies

ERIC Educational Resources Information Center

Altanopoulou, Panagiota; Tselios, Nikolaos; Katsanos, Christos; Georgoutsou, Maria; Panagiotaki, Maria-Antonia

2015-01-01

A considerable interest in using Web 2.0 technologies such as wikis in education has been observed recently. Despite the advantages of the wiki technology, a number of questions concerning design of appropriate activities and their learning effectiveness remain open. In this paper, we present the results of three activities involving first-year…

"Intelligences That Plants Can Pass On": Play Dough, Fun and Teaching Strategies with Insights to Multiple Intelligences

ERIC Educational Resources Information Center

Laughlin, Kevin; Foley, Andi

2012-01-01

The "Intelligences That Plants Can Pass On" is an activity that involves several of Gardner's Multiple Intelligences and was designed for demonstrating the practical use of Multiple Intelligences in delivering education programs to all ages of learners. Instructions are provided for how to implement this activity, and the activity is linked to…

Extracurricular Activity Participation and the Acquisition of Developmental Assets: Differences between Involved and Noninvolved Canadian High School Students

ERIC Educational Resources Information Center

Forneris, Tanya; Camiré, Martin; Williamson, Robert

2015-01-01

In order to prepare students for adulthood and responsible citizenship, most high schools offer extracurricular activities designed to facilitate the learning of a wide range of competencies. The purpose of this study was to examine how participation in a single or a combination of extracurricular school activities for high school students may…

NASA Processes and Requirements for Conducting Human-in-the-Loop Closed Chamber Tests

NASA Technical Reports Server (NTRS)

Barta, Daniel J.; Montz, Michael E.

2004-01-01

NASA has specific processes and requirements that must be followed for tests involving human subjects to be conducted in a safe and effective manner. There are five distinct phases of test operations. Phase one, the test request phase, consists of those activities related to initiating, processing, reviewing, and evaluating the test request. Phase two, the test preparation phase consists of those activities related to planning, coordinating, documenting, and building up the test. Phase three, the test readiness phase consists of those activities related to verifying and reviewing the planned test operations. Phase four, the test activity phase, consists of all pretest operations, functional checkouts, emergency drills, and test operations. Phase five, the post test activity phase, consists of those activities performed once the test is completed, including briefings, documentation of anomalies, data reduction and archiving, and reporting. Project management processes must be followed for facility modifications and major test buildup, which include six phases: initiation and assessment, requirements evaluation, preliminary design, detailed design, use readiness review (URR) and acceptance. Compliance with requirements for safety and quality assurance are documented throughout the test buildup and test operation processes. Tests involving human subjects must be reviewed by the applicable Institutional Review Board (IRB).

Keeping the beat: use of rhythmic music during exercise activities for the elderly with dementia.

PubMed

Mathews, R M; Clair, A A; Kosloski, K

2001-01-01

Involving people with dementia in group exercise activities often presents a challenge. The effects of a recorded instrumental musical accompaniment was evaluated on participation in a series of 14 exercise activities with a group of nursing home residents with dementia. All exercise sessions, specifically designed by physical therapists for older adults, were lead by an activity aide and consisted of a series of seated exercises. Direct observations of resident behavior were conducted over a 25-week period in a reversal experimental design. Results showed increased levels of participation during the experimental condition observations where rhythmic music accompanied the exercise activities. The music intervention was most successful on those generally most willing to participate in social activities.

Synchrony and exertion during dance independently raise pain threshold and encourage social bonding

PubMed Central

Tarr, Bronwyn; Launay, Jacques; Cohen, Emma; Dunbar, Robin

2015-01-01

Group dancing is a ubiquitous human activity that involves exertive synchronized movement to music. It is hypothesized to play a role in social bonding, potentially via the release of endorphins, which are analgesic and reward-inducing, and have been implicated in primate social bonding. We used a 2 × 2 experimental design to examine effects of exertion and synchrony on bonding. Both demonstrated significant independent positive effects on pain threshold (a proxy for endorphin activation) and in-group bonding. This suggests that dance which involves both exertive and synchronized movement may be an effective group bonding activity. PMID:26510676

Optimal Space Station solar array gimbal angle determination via radial basis function neural networks

NASA Technical Reports Server (NTRS)

Clancy, Daniel J.; Oezguener, Uemit; Graham, Ronald E.

1994-01-01

The potential for excessive plume impingement loads on Space Station Freedom solar arrays, caused by jet firings from an approaching Space Shuttle, is addressed. An artificial neural network is designed to determine commanded solar array beta gimbal angle for minimum plume loads. The commanded angle would be determined dynamically. The network design proposed involves radial basis functions as activation functions. Design, development, and simulation of this network design are discussed.

Practical Strategies for Integrating Interprofessional Education and Collaboration into the Curriculum.

PubMed

Prast, Jean; Herlache-Pretzer, Ellen; Frederick, Andrea; Gafni-Lachter, Liat

2016-01-01

Interprofessional collaboration is vital for the provision of quality patient care. Thoughtfully designed educational programs can help students of health professions develop interprofessional competencies and capacities, including values and ethics, roles and responsibilities, interprofessional communication, and teamwork (Interprofessional Education Collaborative Expert Panel, 2011). The authors were involved in developing Interprofessional Education (IPE) activities and simulations to be infused into the curriculums of the various health professions programs in their College. A review of the IPE experiences revealed students greatly benefited from involvement in a diverse set of IPE activities and simulations.

Designing, engineering, and testing wood structures

NASA Technical Reports Server (NTRS)

Gorman, Thomas M.

1992-01-01

The objective of this paper is to introduce basic structural engineering concepts in a clear, simple manner while actively involving students. This project emphasizes the fact that a good design uses materials efficiently. The test structure in this experiment can easily be built and has various design options. Even when the structure is loaded to collapsing, only one or two pieces usually break, leaving the remaining pieces intact and reusable.

Data Form and Availability and the Design of Computerized Retrieval Systems Dealing with Bibliographic Entities.

ERIC Educational Resources Information Center

Brandhorst, W. T.

An analysis of existing computerized data banks in science and technology reveals that nearly half of them involve the storage and retrieval of bibliographic data. Activity in this area has been independent and autonomous. This situation is now giving way to a new environment which involves cooperation, standards, and a rigorous rational analysis…

Case Management in the School Context. A Center Quick Training Aid.

ERIC Educational Resources Information Center

California Univ., Los Angeles. Center for Mental Health in Schools.

When a student is involved with more than one intervener, management of care is a concern. Management of care involves a variety of activity all of which is designed to ensure that student/family interests are well served. At the core is enhanced monitoring focused on the appropriateness of interventions. This quick training aid presents a brief…

High yield bacterial expression, purification and characterisation of bioactive Human Tousled-like Kinase 1B involved in cancer.

PubMed

Bhoir, Siddhant; Shaik, Althaf; Thiruvenkatam, Vijay; Kirubakaran, Sivapriya

2018-03-19

Human Tousled-like kinases (TLKs) are highly conserved serine/threonine protein kinases responsible for cell proliferation, DNA repair, and genome surveillance. Their possible involvement in cancer via efficient DNA repair mechanisms have made them clinically relevant molecular targets for anticancer therapy. Innovative approaches in chemical biology have played a key role in validating the importance of kinases as molecular targets. However, the detailed understanding of the protein structure and the mechanisms of protein-drug interaction through biochemical and biophysical techniques demands a method for the production of an active protein of exceptional stability and purity on a large scale. We have designed a bacterial expression system to express and purify biologically active, wild-type Human Tousled-like Kinase 1B (hTLK1B) by co-expression with the protein phosphatase from bacteriophage λ. We have obtained remarkably high amounts of the soluble and homogeneously dephosphorylated form of biologically active hTLK1B with our unique, custom-built vector design strategy. The recombinant hTLK1B can be used for the structural studies and may further facilitate the development of new TLK inhibitors for anti-cancer therapy using a structure-based drug design approach.

Language Development Resources for Bilingual Bicultural Education: An Aid to Primary Teachers of Mexican American Children.

ERIC Educational Resources Information Center

Dissemination and Assessment Center for Bilingual Education, Austin, TX.

This resource guide is designed as an aid to primary teachers of Mexican-American children. Besides including basic introductory material, the volume provides suggestions for parent involvement, classroom learning activity centers, and extensive resource materials. Classroom learning activity centers include: Art, Book, Communication, Discussion,…

Environmental Science: Activities with Plants of the Southwest.

ERIC Educational Resources Information Center

Hackley, Sharon; Hackley, Mike

In this book for students of all ages, the author introduces unusual recipe ideas for the prickly, odd, and pestiferous plants of the American southwestern desert. Students are involved in cooking activities designed to spark interest in ecology, trigger logical thinking, utilize math skills, and build sound environmental concepts. Care was taken…

Using "Number the Stars" as a Springboard for Doing Social Studies

ERIC Educational Resources Information Center

Putman, Errol

2003-01-01

The Danish experience during the German occupation, presented through the experiences of the Rosen and Johansen families, provides the literary and historical background for the activities the author presents in this article. He designed the four activities for maximum student involvement, with each requiring students to respond to Lois Lowry's…

LSQuiz: A Collaborative Classroom Response System to Support Active Learning through Ubiquitous Computing

ERIC Educational Resources Information Center

Caceffo, Ricardo; Azevedo, Rodolfo

2014-01-01

The constructivist theory indicates that knowledge is not something finished and complete. However, the individuals must construct it through the interaction with the physical and social environment. The Active Learning is a methodology designed to support the constructivism through the involvement of students in their learning process, allowing…

76 FR 66956 - Notice of Availability of the Draft Environmental Impact Statement for the Phoenix Copper Leach...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-28

... Register. The BLM will announce future meetings or hearings and any other public involvement activities at... solvent extraction/electro-winning facility; (5) designation of a new optional use area that could be... years; overall closure and reclamation activities are anticipated to extend approximately 10 years...

Evaluation Method for an App Involving Kitchen Activities.

PubMed

Burzagli, Laura; Gaggioli, Andrea

2017-01-01

An app, developed for the national Italian project "Design for all", is evaluated here. This app supports the user in most of his/her cooking activities. The evaluation process integrates different technologies, such as expert interview, cognitive walkthrough and focus group, to consider different aspects that include, but are not limited to, usability and accessibility.

Neural Activation to Emotional Faces in Adolescents with Autism Spectrum Disorders

ERIC Educational Resources Information Center

Weng, Shih-Jen; Carrasco, Melisa; Swartz, Johnna R.; Wiggins, Jillian Lee; Kurapati, Nikhil; Liberzon, Israel; Risi, Susan; Lord, Catherine; Monk, Christopher S.

2011-01-01

Background: Autism spectrum disorders (ASD) involve a core deficit in social functioning and impairments in the ability to recognize face emotions. In an emotional faces task designed to constrain group differences in attention, the present study used functional MRI to characterize activation in the amygdala, ventral prefrontal cortex (vPFC), and…

Conducting Design Experiments to Support Teachers' Learning: A Reflection from the Field

ERIC Educational Resources Information Center

Cobb, Paul; Zhao, Qing; Dean, Chrystal

2009-01-01

This article focuses on 3 conceptual challenges that we sought to address while conducting a design experiment in which we supported the learning of a group of middle school mathematics teachers. These challenges involved (a) situating teachers' activity in the institutional setting of the schools and district in which they worked, (b) developing…

Engaging Struggling Early Readers to Promote Reading Success: A Pilot Study of Reading by Design

ERIC Educational Resources Information Center

Mendez, Linda M. Raffaele; Pelzmann, Catherine A.; Frank, Michael J.

2016-01-01

In this study, we piloted a Tier 2 intervention designed to improve reading skills among struggling early readers using an intervention that included SRA Reading Mastery, listening-while-reading activities, strategies to increase motivation and engagement in reading, and parent involvement in reading homework. The study included 6 students in…

Engineering Design Processes in Seventh-Grade Classrooms: Bridging the Engineering Education Gap

ERIC Educational Resources Information Center

English, Lyn D.; Hudson, Peter B.; Dawes, Les

2012-01-01

This paper reports on some findings from the first year of a three-year longitudinal study, in which seventh- to ninth-graders were introduced to engineering education. Specifically, the paper addresses students' responses to an initial design activity involving bridge construction, which was implemented at the end of seventh grade. This paper…

9 CFR 71.1 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-01-01

... subchapter, for conducting an active State scrapie program involving the identification of scrapie in sheep... which contains or displays an AIN with an 840 prefix must bear the U.S. shield. The design, size, shape...

9 CFR 71.1 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-01-01

... subchapter, for conducting an active State scrapie program involving the identification of scrapie in sheep... which contains or displays an AIN with an 840 prefix must bear the U.S. shield. The design, size, shape...

PDG Construction, LLC Information Sheet

EPA Pesticide Factsheets

PDG Construction, LLC d/b/a Princeton Design Guild (the Company) is located in Bell Meade, New Jersey. The settlement involves renovation activities conducted at property constructed prior to 1978, located in Hopewell, New Jersey.

Working at the microscope: analysis of the activities involved in diagnostic pathology.

PubMed

Randell, Rebecca; Ruddle, Roy A; Quirke, Phil; Thomas, Rhys G; Treanor, Darren

2012-02-01

To study the current work practice of histopathologists to inform the design of digital microscopy systems. Four gastrointestinal histopathologists were video-recorded as they undertook their routine work. Analysis of the video data shows a range of activities beyond viewing slides involved in reporting a case. There is much overlapping of activities, supported by the 'eyes free' nature of the pathologists' interaction with the microscope. The order and timing of activities varies according to consultant. In order to support the work of pathologists adequately, digital microscopy systems need to provide support for a range of activities beyond viewing slides. Digital microscopy systems should support multitasking, while also providing flexibility so that pathologists can adapt their use of the technology to their own working patterns. © 2011 Blackwell Publishing Ltd.

A Youth-Led, Social Marketing Intervention Run by Adolescents to Encourage Healthy Lifestyles among Younger School Peers (EYTO-Kids Project): A Protocol for Pilot Cluster Randomized Controlled Trial (Spain)

PubMed Central

Aceves-Martins, Magaly; Papell-Garcia, Ignasi; Arola, Lluís; Giralt, Montse; Solà, Rosa

2017-01-01

Introduction: The EYTO-kids (European Youth Tackling Obesity in Adolescents and Children) study aims to increase fruit and/or vegetable consumption and physical activity, decrease sedentary lifestyles, and reduce the intake of sugary drinks and fast food using an innovative methodology based on social marketing and youth involvement. Methods: This study is a pilot school-based cluster randomized controlled 10-month intervention spanning two academic years (2015–2016 and 2016–2017), with eight primary schools and three high schools randomized into and designated the control group and eight primary schools and four high schools designated the intervention group in Reus, Spain. At least 301 younger school peers per group should be included. At the intervention high schools, the adolescent creators (ACs) receive an initial 16-h training session. In total, 26–32 high school ACs (12–14 years) from the four high schools will design and implement four health-promotion activities (1 h/each) for their younger (8–10 years), primary school peers. The control group will not receive any intervention. The outcomes (fruit, vegetable, fast food and sugary drink consumption; physical activity; and sedentary behaviors) of the control and intervention groups will be measured pre- and post-intervention. Conclusion: This study describes a protocol for pilot, peer-led, social marketing and youth-involved intervention, where adolescents design and implement activities for their younger peers to promote healthy lifestyles.

Web-based assessments of physical activity in youth: considerations for design and scale calibration.

PubMed

Saint-Maurice, Pedro F; Welk, Gregory J

2014-12-01

This paper describes the design and methods involved in calibrating a Web-based self-report instrument to estimate physical activity behavior. The limitations of self-report measures are well known, but calibration methods enable the reported information to be equated to estimates obtained from objective data. This paper summarizes design considerations for effective development and calibration of physical activity self-report measures. Each of the design considerations is put into context and followed by a practical application based on our ongoing calibration research with a promising online self-report tool called the Youth Activity Profile (YAP). We first describe the overall concept of calibration and how this influences the selection of appropriate self-report tools for this population. We point out the advantages and disadvantages of different monitoring devices since the choice of the criterion measure and the strategies used to minimize error in the measure can dramatically improve the quality of the data. We summarize strategies to ensure quality control in data collection and discuss analytical considerations involved in group- vs individual-level inference. For cross-validation procedures, we describe the advantages of equivalence testing procedures that directly test and quantify agreement. Lastly, we introduce the unique challenges encountered when transitioning from paper to a Web-based tool. The Web offers considerable potential for broad adoption but an iterative calibration approach focused on continued refinement is needed to ensure that estimates are generalizable across individuals, regions, seasons and countries.

Volunteers in Specialist Palliative Care: A Survey of Adult Services in the United Kingdom

PubMed Central

Burbeck, Rachel; Low, Joe; Sampson, Elizabeth L.; Bravery, Ruth; Hill, Matthew; Morris, Sara; Ockenden, Nick; Payne, Sheila

2014-01-01

Abstract Background: Worldwide, the demand for specialist palliative care is increasing but funding is limited. The role of volunteers is underresearched, although their contribution reduces costs significantly. Understanding what volunteers do is vital to ensure services develop appropriately to meet the challenges faced by providers of palliative care. Objective: The study's objective is to describe current involvement of volunteers with direct patient/family contact in U.K. specialist palliative care. Design: An online survey was sent to 290 U.K. adult hospices and specialist palliative care services involving volunteers covering service characteristics, involvement and numbers of volunteers, settings in which they are involved, extent of involvement in care services, specific activities undertaken in each setting, and use of professional skills. Results: The survey had a 67% response rate. Volunteers were most commonly involved in day care and bereavement services. They entirely ran some complementary therapy, beauty therapy/hairdressing, and pastoral/faith-based care services, and were involved in a wide range of activities, including sitting with dying patients. Conclusions: This comprehensive survey of volunteer activity in U.K. specialist palliative care provides an up-to-date picture of volunteer involvement in direct contact with patients and their families, such as providing emotional care, and the extent of their involvement in day and bereavement services. Further research could focus on exploring their involvement in bereavement care. PMID:24475743

Launch vehicle design and GNC sizing with ASTOS

NASA Astrophysics Data System (ADS)

Cremaschi, Francesco; Winter, Sebastian; Rossi, Valerio; Wiegand, Andreas

2018-03-01

The European Space Agency (ESA) is currently involved in several activities related to launch vehicle designs (Future Launcher Preparatory Program, Ariane 6, VEGA evolutions, etc.). Within these activities, ESA has identified the importance of developing a simulation infrastructure capable of supporting the multi-disciplinary design and preliminary guidance navigation and control (GNC) design of different launch vehicle configurations. Astos Solutions has developed the multi-disciplinary optimization and launcher GNC simulation and sizing tool (LGSST) under ESA contract. The functionality is integrated in the Analysis, Simulation and Trajectory Optimization Software for space applications (ASTOS) and is intended to be used from the early design phases up to phase B1 activities. ASTOS shall enable the user to perform detailed vehicle design tasks and assessment of GNC systems, covering all aspects of rapid configuration and scenario management, sizing of stages, trajectory-dependent estimation of structural masses, rigid and flexible body dynamics, navigation, guidance and control, worst case analysis, launch safety analysis, performance analysis, and reporting.

Self-efficacy as a mediator of children's achievement motivation and in-class physical activity.

PubMed

Gao, Zan; Lochbaum, Marc; Podlog, Leslie

2011-12-01

The present study was designed to examine the mediating effect of self-efficacy on relations of middle school students' four achievement goals with their perceptions of two motivational climates and in-class physical activity in physical education. The four achievement goals (mastery-approach, mastery-avoidance, performance-approach, and performance-avoidance), perceptions of the motivational climate (mastery- and performance-involving climates), and self-efficacy were measured in a sample of 194 students (93 boys, 101 girls) in a public school. Students' in-class physical activity was assessed using Actical Accelerometers. A series of multiple-regression analyses supported the mediating effect of self-efficacy on the relationships among students' mastery-approach goal, perceived mastery-involving climate, and physical activity.

Incorporating Cultural Diversity into an Advanced Speech Communication Course in Listening Using an "Attribution Training" Activity.

ERIC Educational Resources Information Center

Ostermeier, Terry H.

A junior-senior level course in listening focuses on a 2- to 3-day unit on examining communication and cultural diversity. In this unit, the primary element is an activity involving student participation, and the major theme of this activity is cultural values and norms. Attribution training, a technique designed to teach persons from one culture…

Implementation Strategy for Coral Reef Transplantation Methods in Support of Natural Resource Planning, Management and NEPANESDI Project Number 491

DTIC Science & Technology

2016-05-01

species as either threatened or endangered under the Endangered Species Act (ESA) and to designate critical habitat. In a Federal Register notice... designation as “critical habitat.” The designation of critical habitat affects activities that involve a federal permit, license, or funding, and are likely...are not likely to jeopardize the continued existence of a listed species, or destroy or adversely modify its designated critical habitat. In some cases

Connecting Texas to the Poles - IPY outreach at the University of Texas Institute for Geophysics

NASA Astrophysics Data System (ADS)

Stevenoski, S.; Lawver, L.

2007-12-01

This outreach effort at UTIG targets high school teachers and students during the International Polar Year. Four individual activities were designed using a constructivist approach. The activities were integrated into a new website at UTIG specifically designed to help researchers connect with students and teachers. The website and activities serve as a starting point for the scientists to potentially get more involved with individual classrooms and traditional professional science organizations. Students will use accepted scientific knowledge, models, and theories to explain their results and to raise further questions about their investigations. Students will state what they have learned from investigations, relating their inferences to scientific knowledge and to data they have collected. They will explain their data and conclusions in ways that allow others to understand the inquiry that they have conducted. The activities are based upon data sets modified for student use from the UT Polar science community. These Polar data sets will complement student data acquired during the hands on activities central to the student inquiry lessons. The activities are range from traditional classroom lab investigations to Internet based georeferencing and mapping. Researchers and graduate students were actively involved in the development of the final products to insure the accuracy of the science and data used.

RCRA/UST, Superfund, and EPCRA hotline training module. Introduction to superfund community involvement. Directive

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-03-01

This module covers EPA`s Superfund community involvement program, a set of requirements under the National Contingency Plan (NCP) designed to ensure that public is informed about site conditions and given the opportunity to comment on the proposed remedy of a Superfund site. The NCP serves to uphold the public`s right to voice opinions and express concerns about Superfund site activities. EPA must involve communities throughout Superfund process - particularly at critical decision-making steps in the process.

Methodological issues in the design of a rheumatoid arthritis activity score and its cut-offs.

PubMed

Collignon, Olivier

2014-01-01

Activity of rheumatoid arthritis (RA) can be evaluated using several scoring scales based on clinical features. The most widely used one is the Disease Activity Score involving 28 joint counts (DAS28) for which cut-offs were proposed to help physicians classify patients. However, inaccurate scoring can lead to inappropriate medical decisions. In this article some methodological issues in the design of such a score and its cut-offs are highlighted in order to further propose a strategy to overcome them. As long as the issues reviewed in this article are not addressed, results of studies based on standard disease activity scores such as DAS28 should be considered with caution.

'Design of CO-O2 recombination catalysts for closed-cycle CO2 lasers'

NASA Technical Reports Server (NTRS)

Guinn, K.; Goldblum, S.; Noskowski, E.; Herz, R.

1989-01-01

Pulsed CO2 lasers have many applications in aeronautics, space research, weather monitoring and other areas. Full exploitation of the potential of these lasers is hampered by the dissociation of CO2 that occurs during laser operation. The development of closed-cycle CO2 lasers requires active CO-O2 recombination (CO oxidation) catalysts and design methods for implementation of catalysts inside lasers. This paper will discuss the performance criteria and constraints involved in the design of monolith catalyst configurations for use in a closed-cycle laser and will present a design study performed with a computerized design program that had been written. Trade-offs between catalyst activity and dimensions, flow channel dimensions, pressure drop, O2 conversion and other variables will be discussed.

A model for safety and health promotion among Danish farmers.

PubMed

Hjort, Charlotte; Højmose, Poul; Sherson, David

2003-01-01

In 1999, a project concerning the prevention of accidents and occupational diseases was started in Vejle County, Denmark. The aim of the project was to increase the safety and health in farming. The project was based on a participatory strategy. The main principles were local involvement in designing the project, multifaceted activities for defined target-groups and respect for occupational skills and integrity. This multilevel approach involved individuals, groups and organisations. Activities were initiated and adjusted throughout the project. This interactive work remodeling the activities throughout the project period and method encouraged empowerment leaving experiences among the participants. Target groups included farmers, farmers' wives, agricultural advisors, agricultural school teachers, employees and part-time assistants. Activities included dialog-meetings, information meetings in larger and smaller groups, as well as designing of educational safety material, e.g., for children and employees. The project is run with a very low degree of central organisational activities, and is also a so called "bottom-up" project with a low budget. Evaluations are undertaken throughout the project period. If this concept can be implemented in Denmark, it may well be useful in other developed as well as less industrialized countries.

Active Tube-Shaped Actuator with Embedded Square Rod-Shaped Ionic Polymer-Metal Composites for Robotic-Assisted Manipulation

PubMed Central

Liu, Jiayu; Zhu, Denglin; Chen, Hualing

2018-01-01

This paper reports a new technique involving the design, fabrication, and characterization of an ionic polymer-metal composite- (IPMC-) embedded active tube, which can achieve multidegree-of-freedom (MODF) bending motions desirable in many applications, such as a manipulator and an active catheter. However, traditional strip-type IPMC actuators are limited in only being able to generate 1-dimensional bending motion. So, in this paper, we try to develop an approach which involves molding or integrating rod-shaped IPMC actuators into a soft silicone rubber structure to create an active tube. We modified the Nafion solution casting method and developed a complete sequence of a fabrication process for rod-shaped IPMCs with square cross sections and four insulated electrodes on the surface. The silicone gel was cured at a suitable temperature to form a flexible tube using molds fabricated by 3D printing technology. By applying differential voltages to the four electrodes of each IPMC rod-shaped actuator, MDOF bending motions of the active tube can be generated. Experimental results show that such IPMC-embedded tube designs can be used for developing robotic-assisted manipulation. PMID:29770160

Active Tube-Shaped Actuator with Embedded Square Rod-Shaped Ionic Polymer-Metal Composites for Robotic-Assisted Manipulation.

PubMed

Wang, Yanjie; Liu, Jiayu; Zhu, Denglin; Chen, Hualing

2018-01-01

This paper reports a new technique involving the design, fabrication, and characterization of an ionic polymer-metal composite- (IPMC-) embedded active tube, which can achieve multidegree-of-freedom (MODF) bending motions desirable in many applications, such as a manipulator and an active catheter. However, traditional strip-type IPMC actuators are limited in only being able to generate 1-dimensional bending motion. So, in this paper, we try to develop an approach which involves molding or integrating rod-shaped IPMC actuators into a soft silicone rubber structure to create an active tube. We modified the Nafion solution casting method and developed a complete sequence of a fabrication process for rod-shaped IPMCs with square cross sections and four insulated electrodes on the surface. The silicone gel was cured at a suitable temperature to form a flexible tube using molds fabricated by 3D printing technology. By applying differential voltages to the four electrodes of each IPMC rod-shaped actuator, MDOF bending motions of the active tube can be generated. Experimental results show that such IPMC-embedded tube designs can be used for developing robotic-assisted manipulation.

An introduction to the BANNING design automation system for shuttle microelectronic hardware development

NASA Technical Reports Server (NTRS)

Mcgrady, W. J.

1979-01-01

The BANNING MOS design system is presented. It complements rather than supplant the normal design activities associated with the design and fabrication of low-power digital electronic equipment. BANNING is user-oriented and requires no programming experience to use effectively. It provides the user a simulation capability to aid in his circuit design and it eliminates most of the manual operations involved in the layout and artwork generation of integrated circuits. An example of its operation is given and some additional background reading is provided.

78 FR 45201 - Agency Forms Undergoing Paperwork Reduction Act Review

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-26

... design with pre- and post-tests involving a total of six states: three CRCCP grantee states (Alabama... be used to fund the provision of screening and diagnostic tests. Additional program activities such...

Intelligent command and control systems for satellite ground operations

NASA Technical Reports Server (NTRS)

Mitchell, Christine M.

1994-01-01

The Georgia Tech portion of the Intelligent Control Center project includes several complementary activities. Two major activities entail thesis level research; the other activities are either support activities or preliminary explorations (e.g., task analyses) to support the research. The first research activity is the development of principles for the design of active interfaces to support monitoring during real-time supports. It is well known that as the operator's task becomes less active, i.e., more monitoring and less active control, there is concern that the operator will be less involved and less able to rapidly identify anomalous or failure situations. The research project to design active monitoring interfaces is an attempt to remediate this undesirable side-effect of increasingly automated control systems that still depend ultimately on operator supervision. The second research activity is the exploration of the use of case-based reasoning as a way to accumulate operator experience and make it available in computational form.

Paralimbic system and striatum are involved in motivational behavior.

PubMed

Nishimura, Masahiko; Yoshii, Yoshihiko; Watanabe, Jobu; Ishiuchi, Shogo

2009-10-28

Goal-directed rewarded behavior and goal-directed non-rewarded behavior are concerned with motivation. However, the neural substrates involved in goal-directed non-rewarded behaviors are unknown. Using functional magnetic resonance imaging, we investigated the brain activities of healthy individuals during a novel tool use (turning a screwdriver) to elucidate the relationship between the brain mechanism relevant to goal-directed non-rewarded behavior and motivation. We found that our designed behavioral task evoked activities in the orbitofrontal cortex, striatum, anterior insula, lateral prefrontal cortex, and anterior cingulate cortex compared with a meaningless task. These results suggest that activation in these cerebral regions play important roles in motivational behavior without tangible rewards.

To think or not to think: two pathways towards persuasion by short films on AIDS prevention.

PubMed

Igartua, Juan José; Cheng, Lifen; Lopes, Orquídea

2003-01-01

Health messages are designed to stimulate an active cognitive process in those audiences generally with little involvement. The Elaboration Likelihood Model by Petty and Cacioppo sustains that subjects with high involvement and those with low involvement react differently to the persuasive message to which they are exposed. One efficient way to capture the attention of the low involvement audiences is to insert the messages within an entertainment context. Our study attempted to analyze affective and cognitive processes to explain the impact of these new formats, fictional shorts for HIV/AIDS prevention. A 2 x 2 factorial design was used, with involvement in the AIDS issue (high/low) and the type of format (musical/dialogue) as independent variables. The finding showed the better the quality of the short (with dialogue style) the more negative affectivity was stimulated, also the more cognitive processing was induced, and a more favorable attitude towards preventive behavior was stimulated.

Systematic Refinement of a Health Information Technology Time and Motion Workflow Instrument for Inpatient Nursing Care using a Standardized Interface Terminology

PubMed Central

Zhang, Yi; Monsen, Karen A; Adam, Terrence J; Pieczkiewicz, David S; Daman, Megan; Melton, Genevieve B

2011-01-01

Time and motion (T&M) studies provide an objective method to measure the expenditure of time by clinicians. While some instruments for T&M studies have been designed to evaluate health information technology (HIT), these instruments have not been designed for nursing workflow. We took an existing open source HIT T&M study application designed to evaluate physicians in the ambulatory setting and rationally adapted it through empiric observations to record nursing activities in the inpatient setting and linked this instrument to an existing interface terminology, the Omaha System. Nursing activities involved several dimensions and could include multiple activities occurring simultaneously, requiring significant instrument redesign. 94% of the activities from the study instrument mapped adequately to the Omaha System. T&M study instruments require customization in design optimize them for different environments, such as inpatient nursing, to enable optimal data collection. Interface terminologies show promise as a framework for recording and analyzing T&M study data. PMID:22195228

Botulinum Neurotoxin Serotype A Inhibitors: Small-Molecule Mercaptoacetamide Analogs

PubMed Central

Moe, Scott T.; Thompson, Andrew B.; Smith, Genessa M.; Fredenburg, Ross A.; Stein, Ross L.; Jacobson, Alan R

2009-01-01

Botulinum neurotoxin elicits its paralytic activity through a zinc-dependant metalloprotease that cleaves proteins involved in neurotransmitter release. Currently, no drugs are available to reverse the effects of botulinum intoxication. Herein we report the design of a novel series of mercaptoacetamide small-molecule inhibitors active against botulinum neurotoxin serotype A. These analogs show low micromolar inhibitory activity against the isolated enzyme. Structure-activity relationship studies for a series of mercaptoacetamide analogs of 5-amino-3-phenylpyrazole reveal components essential for potent inhibitory activity. PMID:19329331

Vernier Caliper and Micrometer Computer Models Using Easy Java Simulation and Its Pedagogical Design Features--Ideas for Augmenting Learning with Real Instruments

ERIC Educational Resources Information Center

Wee, Loo Kang; Ning, Hwee Tiang

2014-01-01

This paper presents the customization of Easy Java Simulation models, used with actual laboratory instruments, to create active experiential learning for measurements. The laboratory instruments are the vernier caliper and the micrometer. Three computer model design ideas that complement real equipment are discussed. These ideas involve (1) a…

Bioelectrochemical Systems Workshop:Standardized Analyses, Design Benchmarks, and Reporting

DTIC Science & Technology

2012-01-01

related to the exoelectrogenic biofilm activity, and to investigate whether the community structure is a function of design and operational parameters...where should biofilm samples be collected? The most prevalent methods of community characterization in BES studies have entailed phylogenetic ...of function associated with this genetic marker, and in methods that involve polymerase chain reaction (PCR) amplification the quantitative

Launch Deployment Assembly Human Engineering Analysis

NASA Technical Reports Server (NTRS)

Loughead, T.

1996-01-01

This report documents the human engineering analysis performed by the Systems Branch in support of the 6A cargo element design. The human engineering analysis is limited to the extra vehicular activities (EVA) which are involved in removal of various cargo items from the LDA and specific activities concerning deployment of the Space Station Remote Manipulator System (SSRMS).

Inhibition Of Call-Cell Binding By Kipid Assemblies

DOEpatents

Nagy, Jon O. , Bargatze, Robert F.

2003-12-16

This invention relates generally to the field of therapeutic compounds designed to interfere between the binding of ligands and their receptors on cell surface. More specifically, it provides products and methods for inhibiting cell migration and activation using lipid assemblies with surface recognition elements that are specific for the receptors involved in cell migration and activation.

Using Stable Carbon and Nitrogen Isotopes of Hair to Teach about Sustainable Agriculture through Active Learning

ERIC Educational Resources Information Center

Cotton, Jennifer M.; Sheldon, Nathan D.

2013-01-01

The call for reform of science education is nearly three decades old (National Commission on Excellence in Education, 1983), but the implementation of such education improvements in the form of active learning techniques in large enrollment classes remains difficult. Here we present a class project designed to increase student involvement and…

Career Education Classroom Activities: North Dakota, K-12; Elementary (First).

ERIC Educational Resources Information Center

North Dakota State Board for Vocational Education, Bismarck.

The guide's contents are designed as ideas that could be used to develop various career education concepts and objectives at the first grade level. The activities are to be integrated into existing curriculum, sequenced, and adapted to meet the needs of all people involved in education at the local school. The purpose of the guideline, a career…

University of California, Irvine, Student Affirmative Action Five-Year Plan and Planning Process, 1985-1986. Volume III.

ERIC Educational Resources Information Center

Galligani, Dennis J.

An update of the University of California, Irvine, Student Affirmative Action (SAA) plan is presented for 1985-1986. SAA activities planned by both academic and administrative units are covered, such as activities designed to: stimulate greater student involvement, establish clearer life goals and career linkages, enhance cultural awareness, and…

Making It All Count: A Cross-Disciplinary Collaboration Model Incorporating Scholarship, Creative Activity, and Student Engagement

ERIC Educational Resources Information Center

Dailey, Rocky; Hauschild-Mork, Melissa

2017-01-01

This study takes a grounded theory approach as a basis for a case study examining a cross-disciplinary artistic and academic collaborative project involving faculty from the areas of English, music, dance, theatre, design, and visual journalism resulting in the creation of research, scholarly, and creative activity that fosters student engagement…

Inhibition of cell-cell binding by lipid assemblies

DOEpatents

Nagy, Jon O.; Bargatze, Robert F.

2001-05-22

This invention relates generally to the field of therapeutic compounds designed to interfere between the binding of ligands and their receptors on cell surface. More specifically, it provides products and methods for inhibiting cell migration and activation using lipid assemblies with surface recognition elements that are specific for the receptors involved in cell migration and activation.

Keiko, Killer Whale. [Lesson Plan].

ERIC Educational Resources Information Center

Discovery Communications, Inc., Bethesda, MD.

This lesson plan presents activities designed to help students understand that Keiko, the killer whale, lived for a long time in an aquarium and had to be taught to live independently; and that computer users can get updates on how Keiko is doing. The main activity of the lesson involves middle school students working in small groups to produce a…

Computational fluid dynamics (CFD) in the design of a water-jet-drive system

NASA Technical Reports Server (NTRS)

Garcia, Roberto

1994-01-01

NASA/Marshall Space Flight Center (MSFC) has an ongoing effort to transfer to industry the technologies developed at MSFC for rocket propulsion systems. The Technology Utilization (TU) Office at MSFC promotes these efforts and accepts requests for assistance from industry. One such solicitation involves a request from North American Marine Jet, Inc. (NAMJ) for assistance in the design of a water-jet-drive system to fill a gap in NAMJ's product line. NAMJ provided MSFC with a baseline axial flow impeller design as well as the relevant working parameters (rpm, flow rate, etc.). This baseline design was analyzed using CFD, and significant deficiencies identified. Four additional analyses were performed involving MSFC changes to the geometric and operational parameters of the baseline case. Subsequently, the impeller was redesigned by NAMJ and analyzed by MSFC. This new configuration performs significantly better than the baseline design. Similar cooperative activities are planned for the design of the jet-drive inlet.

Computer-Aided Drug Design Methods.

PubMed

Yu, Wenbo; MacKerell, Alexander D

2017-01-01

Computational approaches are useful tools to interpret and guide experiments to expedite the antibiotic drug design process. Structure-based drug design (SBDD) and ligand-based drug design (LBDD) are the two general types of computer-aided drug design (CADD) approaches in existence. SBDD methods analyze macromolecular target 3-dimensional structural information, typically of proteins or RNA, to identify key sites and interactions that are important for their respective biological functions. Such information can then be utilized to design antibiotic drugs that can compete with essential interactions involving the target and thus interrupt the biological pathways essential for survival of the microorganism(s). LBDD methods focus on known antibiotic ligands for a target to establish a relationship between their physiochemical properties and antibiotic activities, referred to as a structure-activity relationship (SAR), information that can be used for optimization of known drugs or guide the design of new drugs with improved activity. In this chapter, standard CADD protocols for both SBDD and LBDD will be presented with a special focus on methodologies and targets routinely studied in our laboratory for antibiotic drug discoveries.

In-vitro engineering of novel bioactivity in the natural enzymes

NASA Astrophysics Data System (ADS)

Tiwari, Vishvanath

2016-10-01

Enzymes catalyze various biochemical functions with high efficiency and specificity. In-vitro design of the enzyme leads to novel bioactivity in this natural biomolecule that give answers of some vital questions like crucial residues in binding with substrate, molecular evolution, cofactor specificity etc. Enzyme engineering technology involves directed evolution, rational designing, semi-rational designing and structure-based designing using chemical modifications. Similarly, combined computational and in-vitro evolution approaches together help in artificial designing of novel bioactivity in the natural enzyme. DNA shuffling, error prone PCR and staggered extension process are used to artificially redesign active site of enzyme, which can alter its efficiency and specificity. Modifications of the enzyme can lead to the discovery of new path of molecular evolution, designing of efficient enzymes, locating active sites and crucial residues, shift in substrate and cofactor specificity. The methods and thermodynamics of in-vitro designing of the enzyme are also discussed. Similarly, engineered thermophilic and psychrophilic enzymes attain substrate specificity and activity of mesophilic enzymes that may also be beneficial for industry and therapeutics.

Lipoxygenase is involved in the control of potato tuber development.

PubMed

Kolomiets, M V; Hannapel, D J; Chen, H; Tymeson, M; Gladon, R J

2001-03-01

Plant lipoxygenases (LOXs) are a functionally diverse class of dioxygenases implicated in physiological processes such as growth, senescence, and stress-related responses. LOXs incorporate oxygen into their fatty acid substrates and produce hydroperoxide fatty acids that are precursors of jasmonic acid and related compounds. Here, we report the involvement of the tuber-associated LOXs, designated the Lox1 class, in the control of tuber growth. RNA hybridization analysis showed that the accumulation of Lox1 class transcripts was restricted to developing tubers, stolons, and roots and that mRNA accumulation correlated positively with tuber initiation and growth. In situ hybridization showed that Lox1 class transcripts accumulated in the apical and subapical regions of the newly formed tuber, specifically in the vascular tissue of the perimedullary region, the site of the most active cell growth during tuber enlargement. Suppression mutants produced by expressing antisense coding sequence of a specific tuber LOX, designated POTLX-1, exhibited a significant reduction in LOX activity in stolons and tubers. The suppression of LOX activity correlated with reduced tuber yield, decreased average tuber size, and a disruption of tuber formation. Our results indicate that the pathway initiated by the expression of the Lox1 class genes of potato is involved in the regulation of tuber enlargement.

Using peer-mediated instruction to support communication involving a student with autism during mathematics activities: A case study.

PubMed

Tan, Paulo; Alant, Erna

2018-01-01

This study employed an A-B singled subject design to explore the extent to which a peer-mediated intervention supported a first-grade student with autism's usage both in purpose and frequency of a speech-generating device (SGD) during mathematics activities. The intervention involved teaching a peer without a disability to encourage the student with autism to use the SGD during partnered mathematics activities. Our analysis involved visual and descriptive examination of trends and patterns over time, and comparison of means between and within phases. We found during the course of this study that (1) the student with autism's level of overall communication, which included the relevancy of these communicative behaviors, increased; (2) the student with autism's level of spontaneous communication acts increased; and (3) the peer became more independent with supporting the student with autism's communication. Implications for future research and practice are provided.

The Advantages Perceived by School Teachers in Engaging Their Students in University-Based Chemistry Outreach Activities

ERIC Educational Resources Information Center

Tuah, Jauyah; Harrison, Timothy G.; Shallcross, Dudley E.

2009-01-01

The value teachers put on university-based outreach activities designed for 14-16 year olds that involves both practical and lecture activities are discussed. A variety of good reasons for attending are provided by the teachers but the role of a School Teacher Fellow in mapping the events to the curriculum is shown to be vital to the success of…

An Impact and Feasibility Evaluation of a Six-Week (Nine Hour) Active Play Intervention on Fathers' Engagement with Their Preschool Children: A Feasibility Study

ERIC Educational Resources Information Center

Houghton, Laura J.; O'Dwyer, Mareesa; Foweather, Lawrence; Watson, Paula; Alford, Simon; Knowles, Zoe R.

2015-01-01

Research has demonstrated the benefits of father involvement with their children and a link between uninvolved fatherhood and societal problems. Children's Centres (n?=?15) received 6?×?90-minute active play sessions designed to foster 6 aspects of parental engagement. Fathers' engagement and attitudes to child physical activity were measured pre-…

Medical education and the arts: a survey of U.S. medical schools.

PubMed

Strickland, Mathew A; Gambala, Cecilia T; Rodenhauser, Paul

2002-01-01

Although the literary arts initiated the movement to include the humanities in medical education, little is known about the incorporation of other art forms. A study was designed to determine the variety of arts-related activities in U.S. medical schools. Questionnaires were mailed twice to each of the U.S. medical school deans requesting information about arts-related required and elective courses, extracurricular activities, course and activity titles, and funding sources. Of 100 respondents (78%), 21 offer arts-related required courses, 42 offer electives, and 89 offer extracurricular activities. School-based funds were listed in 67 schools and endowments in 13. Exposure to a variety of the arts is commonplace in U.S. medical schools. Almost half the schools involve the arts in the curriculum and over two thirds support arts-related extracurricular programs. Further investigation is necessary to determine the numbers of students involved, degree of involvement, and the impact on learning and practice.

The role of hardware in learning engineering fundamentals: An empirical study of engineering design and product analysis activity

NASA Astrophysics Data System (ADS)

Brereton, Margot Felicity

A series of short engineering exercises and design projects was created to help students learn to apply abstract knowledge to physical experiences with hardware. The exercises involved designing machines from kits of materials and dissecting and analyzing familiar household products. Students worked in teams. During the activities students brought their knowledge of engineering fundamentals to bear. Videotape analysis was used to identify and characterize the ways in which hardware contributed to learning fundamental concepts. Structural and qualitative analyses of videotaped activities were undertaken. Structural analysis involved counting the references to theory and hardware and the extent of interleaving of references in activity. The analysis found that there was much more discussion linking fundamental concepts to hardware in some activities than in others. The analysis showed that the interleaving of references to theory and hardware in activity is observable and quantifiable. Qualitative analysis was used to investigate the dialog linking concepts and hardware. Students were found to advance their designs and their understanding of engineering fundamentals through a negotiation process in which they pitted abstract concepts against hardware behavior. Through this process students sorted out theoretical assumptions and causal relations. In addition they discovered design assumptions, functional connections and physical embodiments of abstract concepts in hardware, developing a repertoire of familiar hardware components and machines. Hardware was found to be integral to learning, affecting the course of inquiry and the dynamics of group interaction. Several case studies are presented to illustrate the processes at work. The research illustrates the importance of working across the boundary between abstractions and experiences with hardware in order to learn engineering and physical sciences. The research findings are: (a) the negotiation process by which students discover fundamental concepts in hardware (and three central causes of negotiation breakdown); (b) a characterization of the ways that material systems contribute to learning activities, (the seven roles of hardware in learning); (c) the characteristics of activities that support discovering fundamental concepts in hardware (plus several engineering exercises); (d) a research methodology to examine how students learn in practice.

77 FR 50696 - Proposed Data Collections Submitted for Public Comment and Recommendations

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-22

... design with pre- and post-tests involving a total of six states: Three CRCCP grantee states (Alabama... may be used to fund the provision of screening and diagnostic tests. Additional program activities...

Strategies for Involvement in Wildlife Issues.

ERIC Educational Resources Information Center

Kennedy, Carolyn L.; Nye, Donna I.

1984-01-01

Highlights a workshop with children focusing on the treatment of controversial issues and guidelines typically provided by school districts or organizations. Activities designed to stimulate discussion on three issues (endangered species, acid rain, and predator control) are included. (BC)

Combined effects of altitude and high temperature on complex performance.

DOT National Transportation Integrated Search

1971-04-01

Nine well-trained subjects were tested on a complex performance device designed to assess functions of relevance to aircrew activities. The tests, which involved tracking, monitoring, and mental arithmetic, were performed during exposure to altitude ...

Patient centered integrated clinical resource management.

PubMed

Hofdijk, Jacob

2011-01-01

The impact of funding systems on the IT systems of providers has been enormous and have prevented the implementation of designs to focused on the health issue of patients. The paradigm shift the Dutch Ministry of Health has taken in funding health care has a remarkable impact on the orientation of IT systems design. Since 2007 the next step is taken: the application of the funding concept on chronic diseases using clinical standards as the norm. The focus on prevention involves the patient as an active partner in the care plan. The impact of the new dimension in funding has initiated a process directed to the development of systems to support collaborative working and an active involvement of the patient and its informal carers. This national approach will be presented to assess its international potential, as all countries face the long term care crisis lacking resources to meet the health needs of the population.

Physical activity and senior games participation: benefits, constraints, and behaviors.

PubMed

Cardenas, David; Henderson, Karla A; Wilson, Beth E

2009-04-01

The purpose of the article was to examine the physical activity perceptions and behaviors of older adults who were active participants in a statewide senior games (i.e., North Carolina Senior Games; NCSG) program with its focus on year-round involvement through activities in local communities. A random sample of 440 older adults (55 years and older) completed a questionnaire in 2006 about their participation in community-based senior games. A uniqueness of this study is its focus on active older adults, which provides insight into how to maintain physical involvement. Older adults who were most active perceived the most benefits from senior games but did not necessarily have the fewest constraints. This study of NCSG as an organization designed to promote healthy living in communities offered an example of how a social-ecological framework aimed at health promotion can be applied.

3D Simulation as a Learning Environment for Acquiring the Skill of Self-Management: An Experience Involving Spanish University Students of Education

ERIC Educational Resources Information Center

Cela-Ranilla, Jose María; Esteve-Gonzalez, Vanessa; Esteve-Mon, Francesc; Gisbert-Cervera, Merce

2014-01-01

In this study we analyze how 57 Spanish university students of Education developed a learning process in a virtual world by conducting activities that involved the skill of self-management. The learning experience comprised a serious game designed in a 3D simulation environment. Descriptive statistics and non-parametric tests were used in the…

Human Factors in the Design of the Crew Exploration Vehicle (CEV)

NASA Technical Reports Server (NTRS)

Whitmore, Mihriban; Byrne, Vicky; Holden, Kritina

2007-01-01

NASA s Space Exploration vision for humans to venture to the moon and beyond provides interesting human factors opportunities and challenges. The Human Engineering group at NASA has been involved in the initial phases of development of the Crew Exploration Vehicle (CEV), Orion. Getting involved at the ground level, Human Factors engineers are beginning to influence design; this involvement is expected to continue throughout the development lifecycle. The information presented here describes what has been done to date, what is currently going on, and what is expected in the future. During Phase 1, prior to the contract award to Lockheed Martin, the Human Engineering group was involved in generating requirements, conducting preliminary task analyses based on interviews with subject matter experts in all vehicle systems areas, and developing preliminary concepts of operations based on the task analysis results. In addition, some early evaluations to look at CEV net habitable volume were also conducted. The program is currently in Phase 2, which is broken down into design cycles, including System Readiness Review, Preliminary Design Review, and Critical Design Review. Currently, there are ongoing Human Engineering Technical Interchange Meetings being held with both NASA and Lockheed Martin in order to establish processes, desired products, and schedules. Multiple design trades and quick-look evaluations (e.g. display device layout and external window size) are also in progress. Future Human Engineering activities include requirement verification assessments and crew/stakeholder evaluations of increasing fidelity. During actual flights of the CEV, the Human Engineering group is expected to be involved in in-situ testing and lessons learned reporting, in order to benefit human space flight beyond the initial CEV program.

Circuit Training: Exercise That Counts.

ERIC Educational Resources Information Center

Mosher, Patricia E.; Underwood, Steven A.

1992-01-01

Describes how to assess and implement aerobic circuit training, which involves multistation weight training apparatus, handweights, and aerobic activity equipment to increase cardiovascular fitness and strength. Designed for high school and college students, the circuit requires 25 minutes to complete. (SM)

Outcomes of a statewide anti-tobacco industry youth organizing movement.

PubMed

Dunn, Caroline L; Pirie, Phyllis L; Oakes, J Michael

2004-01-01

To outline the design and present select findings from an evaluation of a statewide anti-tobacco industry youth organizing movement. A telephone survey was administered to teenagers to assess associations between exposure to anti-industry youth organizing activities and tobacco-related attitudes and behaviors. A group-level comparison between areas high and low in youth organizing activities was planned. Methodological obstacles necessitated a subject-level analytic approach, with comparisons being made between youth at higher and lower levels of exposure. Six rural areas (comprising 13 counties) and two urban regions of Minnesota were selected for survey. The study comprised 852 youth, aged 15 to 17 years old, randomly selected from county-specific sampling frames constructed from a marketing research database. Exposure index scores were developed for two types of activities designed to involve youth in the anti-industry program: branding (creating awareness of the movement in general) and messaging (informing about the movement's main messages). Attitudinal outcomes measured attitudes about the tobacco industry and the effectiveness of youth action. Behavioral outcomes included taking action to get involved in the organization, spreading an anti-industry message, and smoking susceptibility. Branding index scores were significantly correlated with taking action to get involved (p < or = .001) and spreading an anti-industry message (p < or = .001). Messaging index scores were significantly correlated with all five attitudinal constructs (all associations, p < or = .001), taking action to get involved (p < or = .001), and spreading an anti-industry message (p < or = . 01). The hypothesized association between messaging scores and susceptibility was not significant. A youth organizing effort, in combination with an intensive countermarketing media campaign, can be an effective strategy for involving youth in tobacco prevention and generating negative attitudes about the industry.

Initial Evaluation of Active Minds: A Student Organization Dedicated to Reducing the Stigma of Mental Illness

ERIC Educational Resources Information Center

McKinney, Kathleen G.

2009-01-01

This study examined whether a new student organization, Active Minds, aimed at increasing awareness of "mental illness" and reducing stigma had an impact on students' stigma and willingness to seek psychological help. Three classes were recruited to become involved in the organization. In a pretest/posttest design, stigma and willingness to seek…

Improving the Interest of High-School Students toward Chemistry by Crime Scene Investigation

ERIC Educational Resources Information Center

Basso, A.; Chiorri, C.; Bracco, F.; Carnasciali, M. M.; Alloisio, M.; Grotti, M.

2018-01-01

Improving the interest of high-school students towards chemistry (and science in general) is one of the goals of the Italian Ministry of Education. To this aim, we designed a context-based activity that actively involved students in six different laboratory experiences interconnected by a case study of the murder of Miss Scarlet, from the famous…

The Effect of Combining Analogy-Based Simulation and Laboratory Activities on Turkish Elementary School Students' Understanding of Simple Electric Circuits

ERIC Educational Resources Information Center

Unlu, Zeynep Koyunlu; Dokme, Ibilge

2011-01-01

The purpose of this study was to investigate whether the combination of both analogy-based simulation and laboratory activities as a teaching tool was more effective than utilizing them separately in teaching the concepts of simple electricity. The quasi-experimental design that involved 66 seventh grade students from urban Turkish elementary…

Case Study Evaluating Just-In-Time Teaching and Peer Instruction Using Clickers in a Quantum Mechanics Course

ERIC Educational Resources Information Center

Sayer, Ryan; Marshman, Emily; Singh, Chandralekha

2016-01-01

Just-in-Time Teaching (JiTT) is an instructional strategy involving feedback from students on prelecture activities in order to design in-class activities to build on the continuing feedback from students. We investigate the effectiveness of a JiTT approach, which included in-class concept tests using clickers in an upper-division quantum…

For the Love of Statistics: Appreciating and Learning to Apply Experimental Analysis and Statistics through Computer Programming Activities

ERIC Educational Resources Information Center

Mascaró, Maite; Sacristán, Ana Isabel; Rufino, Marta M.

2016-01-01

For the past 4 years, we have been involved in a project that aims to enhance the teaching and learning of experimental analysis and statistics, of environmental and biological sciences students, through computational programming activities (using R code). In this project, through an iterative design, we have developed sequences of R-code-based…

Career Education Classroom Activities: North Dakota, K-12: Elementary (Kindergarten).

ERIC Educational Resources Information Center

North Dakota State Board for Vocational Education, Bismarck.

The guide's concepts are designed as ideas that could be used to develop various career education concepts and objectives at the kindergarten level. The activities are to be integrated into the existing curriculum, sequenced, and adapted to meet the needs of all people involved in education at the local school. The purpose of the guideline, a K-6…

On the Design and Test of a Liquid Injection Electric Thruster

NASA Technical Reports Server (NTRS)

Jones, T. A.; Kenney, J. T.; Youmans, E. H.

1973-01-01

A liquid injection electric thruster (LINJET) was designed and tested. The results of the tests were very encouraging with thruster performance levels well in excess of design goals. Supporting activities to the engine design and test included a five-million pulse life test on the main capacitor, a 46-million pulse test on the trigger electronics, design and fabrication of a zero resistance torque connector for use with the torsional pendulum thrust stand, design and fabrication of a logic box for control of engine firing, and a physical and chemical properties characterization of the perfluorocarbon propellant. While the results were encouraging, testing was limited, as many problems existed with the design. The most significant problem was involved with excessive propellant flow which contributed to false triggering and shorting. Low power active thermal control of the propellant storage cavity, coupled with a re-evaluation of the injection ring pore size and area exposed to the main capacitor discharge are areas that should be investigated should this design be carried forward.

Instructional games and activities for criticality safety training

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bullard, B.; McBride, J.

1993-01-01

During the past several years, the Training and Management Systems Division (TMSD) staff of Oak Ridge Institute for Science and Education (ORISE) has designed and developed nuclear criticality safety (NCS) training programs that focus on high trainee involvement through the use of instructional games and activities. This paper discusses the instructional game, initial considerations for developing games, advantages and limitations of games, and how games may be used in developing and implementing NCS training. It also provides examples of the various instructional games and activities used in separate courses designed for Martin Marietta Energy Systems (MMES's) supervisors and U.S. Nuclearmore » Regulatory Commission (NRC) fuel facility inspectors.« less

Silicon production process evaluations

NASA Technical Reports Server (NTRS)

1982-01-01

Chemical engineering analyses involving the preliminary process design of a plant (1,000 metric tons/year capacity) to produce silicon via the technology under consideration were accomplished. Major activities in the chemical engineering analyses included base case conditions, reaction chemistry, process flowsheet, material balance, energy balance, property data, equipment design, major equipment list, production labor and forward for economic analysis. The process design package provided detailed data for raw materials, utilities, major process equipment and production labor requirements necessary for polysilicon production in each process.

The impact of active stakeholder involvement on recruitment, retention and engagement of schools, children and their families in the cluster randomised controlled trial of the Healthy Lifestyles Programme (HeLP): a school-based intervention to prevent obesity.

PubMed

Lloyd, J; McHugh, C; Minton, J; Eke, H; Wyatt, K

2017-08-14

Recruitment and retention of participants is crucial for statistical power and internal and external validity and participant engagement is essential for behaviour change. However, many school-based interventions focus on programme content rather than the building of supportive relationships with all participants and tend to employ specific standalone strategies, such as incentives, to improve retention. We believe that actively involving stakeholders in both intervention and trial design improves recruitment and retention and increases the chances of creating an effective intervention. The Healthy Lifestyles Programme, HeLP (an obesity prevention programme for children 9-10 years old) was developed using intervention mapping and involved extensive stakeholder involvement in both the design of the trial and the intervention to ensure that: (i) delivery methods were suitably engaging, (ii) deliverers had the necessary skills and qualities to build relationships and (iii) the intervention dovetailed with the National Curriculum. HeLP was a year-long intervention consisting of 4 multi-component phases using a range of delivery methods. We recruited 1324 children from 32 schools from the South West of England to a cluster-randomised controlled trial to determine the effectiveness of HeLP in preventing obesity. The primary outcome was change in body mass index standard deviation score (BMI SDS) at 24 months post randomisation. Secondary outcomes included additional anthropometric and behavioural (physical activity and diet) measures at 18 and 24 months. Anthropometric and behavioural measures were taken in 99%, 96% and 94% of children at baseline, 18 and 24 months, respectively, with no differential follow up between the control and intervention groups at each time point. All children participated in the programme and 92% of children and 77% of parents across the socio-economic spectrum were considered to have actively engaged with HeLP. We attribute our excellent retention and engagement results to the high level of stakeholder involvement in both trial and intervention design, the building of relationships using appropriate personnel and creative delivery methods that are accessible to children and their families across the social spectrum. International Standard Randomised Controlled Trials Register, ISRCTN15811706 . Registered on 1 May 2012.

76 FR 71048 - Assistance to Firefighters Grant Program

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-16

... the highest-scoring applications for awards. Applications that involve interoperable communications... categories: (1) Activities designed to reach high- risk target groups and mitigate incidences of death and... communications project is consistent with the Statewide Communications Interoperability Plan (SCIP). If the State...

75 FR 39054 - Agency Information Collection Activities: Submission for the Office of Management and Budget (OMB...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-07

... feedback to the industry. These forms are designed to provide the information necessary for engineering... the NRC worldwide Web site: http://www.nrc.gov/public-involve/doc-comment/omb/index.html . The...

IVHS Denver Metro Area, Master Plan, Appendix A, Project Descriptions

DOT National Transportation Integrated Search

1994-02-01

THIS ACTIVITY INVOLVES THE CONCEPTUAL DESIGN, CONSTRUCTION AND IMPLEMENTATION OF A TRAFFIC OPERATIONS CENTER (TOC) FOR THE DENVER AREA. : ESTABLISHING A TOC IS CENTRAL TO THE SUCCESS OF IVHS IN THE DENVER AREA.ITS IMPORTANCE WILL CONTINUE BEYOND T...

Involving Teachers in Environmental Education

ERIC Educational Resources Information Center

Ritz, William C.

1977-01-01

This article describes several trans-disciplinary summer institute designs and the general content of two teacher inservice education courses which have been established through the Environmental Studies Institute (ESI) of Syracuse University. Five activities for use in inservice workshops are identified and described. (BT)

Humane Education: Science, Technology, and Society in the English Classroom.

ERIC Educational Resources Information Center

Emeigh, Tonya Huber

1988-01-01

Presents "Beastly Thoughts," a holistic writing module designed to involve students in decision-making processes about socially relevant issues regarding animals. Provides 48 activities for investigation and lists 33 references for possible book reviews. Includes 38 references. (MVL)

Analysis of Life-Cycle Costs and Market Applications of Flywheel Energy-Storage Transit Vehicles

DOT National Transportation Integrated Search

1979-07-01

The Urban Mass Transportation Administration (UMTA) has recently completed the Phase I activities of its Flywheel Energy Storage Program involving an analysis of the operational requirements and the conceptual design of flywheel energy storage vehicl...

Carbachol-mediated endocytosis of NHE3 involves a clathrin-independent mechanism requiring lipid rafts and Cdc42.

PubMed

Zachos, Nicholas C; Alamelumangpuram, Bharath; Lee, Luke J; Wang, Peng; Kovbasnjuk, Olga

2014-01-01

In intestinal epithelial cells, acute regulation of the brush border Na(+)/H(+) exchanger, NHE3, usually occurs by changes in endocytosis and/or exocytosis. Constitutive NHE3 endocytosis involves clathrin. Carbachol (CCH), which elevates intracellular Ca(2+) ([Ca(2+)]i), decreases NHE3 activity and stimulates endocytosis; however, the mechanism involved in calcium-mediated endocytosis of NHE3 is unclear. A pool of NHE3 resides in lipid rafts, which contributes to basal, but not cAMP-mediated, NHE3 trafficking, suggesting that an alternative mechanism exists for NHE3 endocytosis. Cdc42 was demonstrated to play an integral role in some cases of cholesterol-sensitive, clathrin-independent endocytosis. Therefore, the current study was designed to test the hypotheses that (1) clathrin-mediated endocytosis (CME) is involved in constitutive, but not CCH-mediated, endocytosis of NHE3, and (2) CCH-mediated endocytosis of NHE3 occurs through a lipid raft, activated Cdc42-dependent pathway that does not involve clathrin. The role of Cdc42 and lipid rafts on NHE3 activity and endocytosis were investigated in polarized Caco-2/BBe cells using pharmacological and shRNA knockdown approaches. Basal NHE3 activity was increased in the presence of CME blockers (chlorpromazine; K(+) depletion) supporting previous reports that constitutive NHE3 endocytosis is clathrin dependent. In contrast, CCH-inhibition of NHE3 activity was abolished in Caco-2/BBe cells treated with MβCD (to disrupt lipid rafts) as well as in Cdc42 knockdown cells but was unaffected by CME blockers. CCH-mediated inhibition of NHE3 activity is not dependent on clathrin and involves lipid rafts and requires Cdc42. © 2014 S. Karger AG, Basel.

Carbachol-Mediated Endocytosis of NHE3 Involves a Clathrin-Independent Mechanism Requiring Lipid Rafts and Cdc42

PubMed Central

Zachos, Nicholas C.; Alamelumangpuram, Bharath; Lee, Luke J.; Wang, Peng; Kovbasnjuk, Olga

2014-01-01

Background In intestinal epithelial cells, acute regulation of the brush border Na+/H+ exchanger, NHE3, usually occurs by changes in endocytosis and/or exocytosis. Constitutive NHE3 endocytosis involves clathrin. Carbachol (CCH), which elevates intracellular Ca2+ ([Ca2+]i), decreases NHE3 activity and stimulates endocytosis; however, the mechanism involved in calcium-mediated endocytosis of NHE3 is unclear. A pool of NHE3 resides in lipid rafts, which contributes to basal, but not cAMP-mediated, NHE3 trafficking, suggesting that an alternative mechanism exists for NHE3 endocytosis. Cdc42 was demonstrated to play an integral role in some cases of cholesterol-sensitive, clathrin-independent endocytosis. Therefore, the current study was designed to test the hypotheses that (1) clathrin-mediated endocytosis (CME) is involved in constitutive, but not CCH-mediated, endocytosis of NHE3, and (2) CCH-mediated endocytosis of NHE3 occurs through a lipid raft, activated Cdc42-dependent pathway that does not involve clathrin. Methods The role of Cdc42 and lipid rafts on NHE3 activity and endocytosis were investigated in polarized Caco-2/BBe cells using pharmacological and shRNA knockdown approaches. Results Basal NHE3 activity was increased in the presence of CME blockers (chlorpromazine; K+ depletion) supporting previous reports that constitutive NHE3 endocytosis is clathrin dependent. In contrast, CCH-inhibition of NHE3 activity was abolished in Caco-2/BBe cells treated with MβCD (to disrupt lipid rafts) as well as in Cdc42 knockdown cells but was unaffected by CME blockers. Conclusion CCH-mediated inhibition of NHE3 activity is not dependent on clathrin and involves lipid rafts and requires Cdc42. PMID:24713550

Guided Inquiry Facilitated Blended Learning to Improve Metacognitive and Learning Outcome of High School Students

NASA Astrophysics Data System (ADS)

Suwono, H.; Susanti, S.; Lestari, U.

2017-04-01

The learning activities that involve the students to learn actively is one of the characteristics of a qualified education. The learning strategy that involves students’ active learning is guided inquiry. Learning problems today are growing metacognitive skills and cognitive learning outcomes. It is the research and development of learning module by using 4D models of Thiagarajan. The first phase is Define, which analyses the problems and needs required by the prior preparation of the module. The second phase is Design, which formulates learning design and devices to obtain the initial draft of learning modules. The third stage is Develop, which is developing and writing module, module validation, product testing, revision, and the resulting an end-product results module development. The fourth stage is Disseminate, which is disseminating of the valid products. Modules were validated by education experts, practitioners, subject matter experts, and expert of online media. The results of the validation module indicated that the module was valid and could be used in teaching and learning. In the validation phase of testing methods, we used experiments to know the difference of metacognitive skills and learning outcomes between the control group and experimental group. The experimental design was a one group pretest-posttest design. The results of the data analysis showed that the modules could enhance metacognitive skills and learning outcomes. The advantages of this module is as follows, 1) module is accompanied by a video link on a website that contains practical activities that are appropriate to Curriculum 2013, 2) module is accompanied by a video link on a website that contains about manual laboratory activities that will be used in the classroom face-to-face, so that students are ready when doing laboratory activities, 3) this module can be online through chat to increase students’ understanding. The disadvantages of this module are the material presented in the modules is limited. It is suggested that for the better utilisation of the online activities, students should be present at every meeting of the activities, so as to make all the students participate actively. It is also suggested that school set up facilities to support blended learning.

Preliminary evidence that self-efficacy predicts physical activity in multiple sclerosis.

PubMed

Motl, Robert W; McAuley, Edward; Doerksen, Shawna; Hu, Liang; Morris, Katherine S

2009-09-01

Individuals with multiple sclerosis (MS) are less physically active than non diseased people. One method for increasing physical activity levels involves the identification of factors that correlate with physical activity and that are modifiable by a well designed intervention. This study examined two types of self-efficacy as cross-sectional and prospective correlates of objectively measured physical activity in 16 individuals with a diagnosis of MS. The participants completed two measures of self-efficacy and then wore an accelerometer for a 5-day period at baseline and then at 3 months follow-up. Self-efficacy for continued physical activity was associated with baseline and follow-up levels of physical activity. Self-efficacy for overcoming barriers was associated with follow-up levels of physical activity and change in physical activity across a 3-month period. Researchers should consider self-efficacy as a possible component of an intervention that is designed to increase physical activity levels in those with MS. International Journal of Rehabilitation Research

Revealing the functional neuroanatomy of intrinsic alertness using fMRI: methodological peculiarities.

PubMed

Clemens, Benjamin; Zvyagintsev, Mikhail; Sack, Alexander T; Sack, Alexander; Heinecke, Armin; Willmes, Klaus; Sturm, Walter

2011-01-01

Clinical observations and neuroimaging data revealed a right-hemisphere fronto-parietal-thalamic-brainstem network for intrinsic alertness, and additional left fronto-parietal activity during phasic alertness. The primary objective of this fMRI study was to map the functional neuroanatomy of intrinsic alertness as precisely as possible in healthy participants, using a novel assessment paradigm already employed in clinical settings. Both the paradigm and the experimental design were optimized to specifically assess intrinsic alertness, while at the same time controlling for sensory-motor processing. The present results suggest that the processing of intrinsic alertness is accompanied by increased activity within the brainstem, thalamus, anterior cingulate gyrus, right insula, and right parietal cortex. Additionally, we found increased activation in the left hemisphere around the middle frontal gyrus (BA 9), the insula, the supplementary motor area, and the cerebellum. Our results further suggest that rather minute aspects of the experimental design may induce aspects of phasic alertness, which in turn might lead to additional brain activation in left-frontal areas not normally involved in intrinsic alertness. Accordingly, left BA 9 activation may be related to co-activation of the phasic alertness network due to the switch between rest and task conditions functioning as an external warning cue triggering the phasic alertness network. Furthermore, activation of the intrinsic alertness network during fixation blocks due to enhanced expectancy shortly before the switch to the task block might, when subtracted from the task block, lead to diminished activation in the typical right hemisphere intrinsic alertness network. Thus, we cautiously suggest that--as a methodological artifact--left frontal activations might show up due to phasic alertness involvement and intrinsic alertness activations might be weakened due to contrasting with fixation blocks, when assessing the functional neuroanatomy of intrinsic alertness with a block design in fMRI studies.

Revealing the Functional Neuroanatomy of Intrinsic Alertness Using fMRI: Methodological Peculiarities

PubMed Central

Clemens, Benjamin; Zvyagintsev, Mikhail; Sack, Alexander; Heinecke, Armin; Willmes, Klaus; Sturm, Walter

2011-01-01

Clinical observations and neuroimaging data revealed a right-hemisphere fronto-parietal-thalamic-brainstem network for intrinsic alertness, and additional left fronto-parietal activity during phasic alertness. The primary objective of this fMRI study was to map the functional neuroanatomy of intrinsic alertness as precisely as possible in healthy participants, using a novel assessment paradigm already employed in clinical settings. Both the paradigm and the experimental design were optimized to specifically assess intrinsic alertness, while at the same time controlling for sensory-motor processing. The present results suggest that the processing of intrinsic alertness is accompanied by increased activity within the brainstem, thalamus, anterior cingulate gyrus, right insula, and right parietal cortex. Additionally, we found increased activation in the left hemisphere around the middle frontal gyrus (BA 9), the insula, the supplementary motor area, and the cerebellum. Our results further suggest that rather minute aspects of the experimental design may induce aspects of phasic alertness, which in turn might lead to additional brain activation in left-frontal areas not normally involved in intrinsic alertness. Accordingly, left BA 9 activation may be related to co-activation of the phasic alertness network due to the switch between rest and task conditions functioning as an external warning cue triggering the phasic alertness network. Furthermore, activation of the intrinsic alertness network during fixation blocks due to enhanced expectancy shortly before the switch to the task block might, when subtracted from the task block, lead to diminished activation in the typical right hemisphere intrinsic alertness network. Thus, we cautiously suggest that – as a methodological artifact – left frontal activations might show up due to phasic alertness involvement and intrinsic alertness activations might be weakened due to contrasting with fixation blocks, when assessing the functional neuroanatomy of intrinsic alertness with a block design in fMRI studies. PMID:21984928

Involving people with dementia in developing an interactive web tool for shared decision-making: experiences with a participatory design approach.

PubMed

Span, Marijke; Hettinga, Marike; Groen-van de Ven, Leontine; Jukema, Jan; Janssen, Ruud; Vernooij-Dassen, Myrra; Eefsting, Jan; Smits, Carolien

2018-06-01

The aim of this study was at gaining insight into the participatory design approach of involving people with dementia in the development of the DecideGuide, an interactive web tool facilitating shared decision-making in their care networks. An explanatory case study design was used when developing the DecideGuide. A secondary analysis focused on the data gathered from the participating people with dementia during the development stages: semi-structured interviews (n = 23), four focus group interviews (n = 18), usability tests (n = 3), and a field study (n = 4). Content analysis was applied to the data. Four themes showed to be important regarding the participation experiences of involving people with dementia in research: valuable feedback on content and design of the DecideGuide, motivation to participate, perspectives of people with dementia and others about distress related to involvement, and time investment. People with dementia can give essential feedback and, therefore, their contribution is useful and valuable. Meaningful participation of people with dementia takes time that should be taken into account. It is important for people with dementia to be able to reciprocate the efforts others make and to feel of significance to others. Implications for Rehabilitation People with dementia can contribute meaningfully to the content and design and their perspective is essential for developing useful and user-friendly tools. Participating in research activities may contribute to social inclusion, empowerment, and quality of life of people with dementia.

Overexpression of Human Senescence Marker Protein 30 in Mice Fails to Offer Protection Against Challenge with Organophosphorus Compounds

DTIC Science & Technology

2011-09-01

poisoning. Toxicology 233: 145-154. 2. Gray AP (1984) Design and structure- activity relationships of antidotes to organophosphorus anticholinesterase ...and is being actively pursued. One approach under investigation is the development of human proteins as bioscavengers that sequester or hydrolyze...the major roles described for SMP30 is in maintaining Ca2+ homeostasis by activating enzymes involved in the regulation of Ca2+ pumps localized in

Identifying environmental sounds: a multimodal mapping study

PubMed Central

Tomasino, Barbara; Canderan, Cinzia; Marin, Dario; Maieron, Marta; Gremese, Michele; D'Agostini, Serena; Fabbro, Franco; Skrap, Miran

2015-01-01

Our environment is full of auditory events such as warnings or hazards, and their correct recognition is essential. We explored environmental sounds (ES) recognition in a series of studies. In study 1 we performed an Activation Likelihood Estimation (ALE) meta-analysis of neuroimaging experiments addressing ES processing to delineate the network of areas consistently involved in ES processing. Areas consistently activated in the ALE meta-analysis were the STG/MTG, insula/rolandic operculum, parahippocampal gyrus and inferior frontal gyrus bilaterally. Some of these areas truly reflect ES processing, whereas others are related to design choices, e.g., type of task, type of control condition, type of stimulus. In study 2 we report on 7 neurosurgical patients with lesions involving the areas which were found to be activated by the ALE meta-analysis. We tested their ES recognition abilities and found an impairment of ES recognition. These results indicate that deficits of ES recognition do not exclusively reflect lesions to the right or to the left hemisphere but both hemispheres are involved. The most frequently lesioned area is the hippocampus/insula/STG. We made sure that any impairment in ES recognition would not be related to language problems, but reflect impaired ES processing. In study 3 we carried out an fMRI study on patients (vs. healthy controls) to investigate how the areas involved in ES might be functionally deregulated because of a lesion. The fMRI evidenced that controls activated the right IFG, the STG bilaterally and the left insula. We applied a multimodal mapping approach and found that, although the meta-analysis showed that part of the left and right STG/MTG activation during ES processing might in part be related to design choices, this area was one of the most frequently lesioned areas in our patients, thus highlighting its causal role in ES processing. We found that the ROIs we drew on the two clusters of activation found in the left and in the right STG overlapped with the lesions of at least 4 out of the 7 patients' lesions, indicating that the lack of STG activation found for patients is related to brain damage and is crucial for explaining the ES deficit. PMID:26539096

Computational fluid dynamics for propulsion technology: Geometric grid visualization in CFD-based propulsion technology research

NASA Technical Reports Server (NTRS)

Ziebarth, John P.; Meyer, Doug

1992-01-01

The coordination is examined of necessary resources, facilities, and special personnel to provide technical integration activities in the area of computational fluid dynamics applied to propulsion technology. Involved is the coordination of CFD activities between government, industry, and universities. Current geometry modeling, grid generation, and graphical methods are established to use in the analysis of CFD design methodologies.

Exciting New Take on a Classic: Crash Testing Activity Puts the Egg in the Driver's Seat

ERIC Educational Resources Information Center

Board, Keith

2011-01-01

An excellent common activity in technology and engineering classes involves dropping an egg from a significant height in a protective device designed and built by students. This article describes how the author uses the classic "egg drop" as an inspiration to have students modify a small crash test vehicle that speeds down a track and crashes into…

Exciting New Take on a Classic: Crash Test Activity Puts the Egg in the Driver's Seat

ERIC Educational Resources Information Center

Board, Keith

2011-01-01

An excellent common activity in technology and engineering classes involves dropping an egg from a significant height in a protective device designed and built by students. This article describes how the author uses the classic "egg drop" as an inspiration to have students modify a small crash test vehicle that speeds down a track and crashes into…

The Use of Parent Involved Take-Home Science Activities during Student Teaching: Understanding the Challenges of Implementation

ERIC Educational Resources Information Center

Zarazinski, Jill

2010-01-01

The purpose of this study was to identify student teachers use and implementation of "Science in a Bag" when it was no longer a required course-based assessment. This take-home science activity acted as the elaboration component of the 5Es lesson teacher candidates designed and taught in the classroom, utilized household items, and directly…

COMPUTER-AIDED DRUG DISCOVERY AND DEVELOPMENT (CADDD): in silico-chemico-biological approach

PubMed Central

Kapetanovic, I.M.

2008-01-01

It is generally recognized that drug discovery and development are very time and resources consuming processes. There is an ever growing effort to apply computational power to the combined chemical and biological space in order to streamline drug discovery, design, development and optimization. In biomedical arena, computer-aided or in silico design is being utilized to expedite and facilitate hit identification, hit-to-lead selection, optimize the absorption, distribution, metabolism, excretion and toxicity profile and avoid safety issues. Commonly used computational approaches include ligand-based drug design (pharmacophore, a 3-D spatial arrangement of chemical features essential for biological activity), structure-based drug design (drug-target docking), and quantitative structure-activity and quantitative structure-property relationships. Regulatory agencies as well as pharmaceutical industry are actively involved in development of computational tools that will improve effectiveness and efficiency of drug discovery and development process, decrease use of animals, and increase predictability. It is expected that the power of CADDD will grow as the technology continues to evolve. PMID:17229415

Toward a Psychological Science of Advanced Technology Design for Older Adults

PubMed Central

Fisk, Arthur D.

2010-01-01

Objectives. Technology represents advances in knowledge that change the way humans perform tasks. Ideally, technology will make the task easier, more efficient, safer, or perhaps more pleasurable. Unfortunately, new technologies can sometimes make a task more difficult, slower, dangerous, or perhaps more frustrating. Older adults interact with a variety of technologies in the course of their daily activities and thus products should be designed to be used by people of varying ages. Methods. In this article, we provide an overview of what psychology has to offer to the design of technology—from understanding what people need, to identifying their preferences for design characteristics, and to defining their capabilities and limitations that will influence technology interactions. Results. We identify how research in the field of psychology and aging has advanced understanding of technology interactions and how research on technology interactions can inform theories of aging. Discussion. Design for aging involves understanding the unique capabilities and limitations of older adults; identifying their needs, preferences, and desires for technology in their lives; and involving them in the design process. PMID:20833690

GROWING SEEDS, TEACHER'S GUIDE.

ERIC Educational Resources Information Center

Elementary Science Study, Newton, MA.

THIS TEACHER'S GUIDE IS DESIGNED FOR USE WITH AN ELEMENTARY SCIENCE STUDY UNIT, "GROWING SEEDS," IN WHICH SUCH BASIC SCIENCE SKILLS AND PROCESSES AS MEASUREMENT, OBSERVATION, AND HYPOTHESIS FORMATION ARE INTRODUCED THROUGH STUDENT ACTIVITIES INVOLVING SEEDS, GERMINATION, AND SEEDLING GROWTH. THE MATERIALS WERE DEVELOPED FOR USE IN…

More than just ticking a box…how patient and public involvement improved the research design and funding application for a project to evaluate a cycling intervention for hip osteoarthritis.

PubMed

Andrews, Lisa M; Allen, Helen; Sheppard, Zoë A; Baylis, Guy; Wainwright, Thomas W

2015-01-01

Involving patients and the public in research helps to ensure that research remains relevant, and has an impact on the people it aims to benefit. Funding bodies now require patients and the public to be involved at all stages of research. Patients and members of the public were involved from the outset in research into a cycling and education programme for hip osteoarthritis. A group discussion took place with six participants from a trial of the programme. The group provided feedback on several areas including the relevance of the research, how the researchers proposed to recruit patients, the research design, the programme itself (including what they liked/didn't like about it), and how the researchers could publicise the research findings. The feedback received was invaluable, and helped shape the entire research project and funding application. The cycling and education programme has been extended in line with comments received from the group. They also helped identify the best way of gathering information from research participants and had suggestions for sharing the results, both of which were incorporated into the funding application. Often involving patients and the public in research can be seen as a 'tick box' exercise. However, this example shows how crucial involving patients and the public in research design is. It also shows how the funding application was made stronger as a result of patient input. Researchers should be encouraged to work closely with patients and the public to ensure their research is of the highest quality. Background Involving patients and the public in research is an essential activity to ensure relevant, accessible, and appropriate research. There is increasing obligation from funding bodies on researchers to have well thought through plans for involving the public, and indeed it is often a condition for funding. Patient and public involvement activity in this project was conducted to inform a funding application to investigate the effectiveness of a cycling and education intervention in the treatment of hip osteoarthritis. Methods Six participants from a feasibility programme of the intervention attended a two-hour patient and public involvement consultation group to provide feedback on various aspects of the proposed research and intervention. During the consultation group, two independent facilitators followed a detailed plan formulated with the research team. Feedback was validated by the attendees via email following the consultation, and a report was issued to the research team. Further feedback on subsequent changes was sought via email and telephone with members of a Patient Advisory Group. Results The patient and public involvement consultation group provided invaluable feedback and suggestions which impacted on the design and quality of the research project and the intervention. Key changes to the intervention included extending the duration of the cycling programme from six to eight weeks, and inclusion of an exercise diary to promote adherence to the intervention. Key feedback regarding the design of the research and funding application included suggestions for methods of dissemination, and confirmation of the primary outcome measure. Conclusions Patient and public involvement was crucial to the design of the proposed research and intervention. It informed many aspects of the research design and made the funding application stronger as a result. Involving patients and the public in research is much more than an obligation, or 'tick box' exercise. It can change and improve research quality, which is crucial when answering questions that are meaningful and important to patients, and which leads to increased impact. Collaboration with patients and the public should be planned and reported from the conception of a research idea where the impact of such input can be considerable.

Building inhabitant feedback: Creating a reflective practice for environmental design using activity theory

NASA Astrophysics Data System (ADS)

Cunningham, Dara Suzanne

The way buildings are designed now, there is little feedback from use involved in the design process. Attempts to correct this problem have been made in the form of Post Occupancy Evaluations (POEs) for 50-years but have largely failed. POEs are the accepted method for environmental designers to collect feedback about buildings in use. They are infrequently conducted, after the building is built, in a one-time only evaluation, and not funded as part of the build process. Other products receive feedback about the design in use from online critiques. Online critiques could provide a platform for feedback from actors engaged with buildings in use for environmental designers to utilize in developing reflective design rationale to avoid adverse consequences in future designs or correct consequences in past and current designs. Since buildings constitute such a large part of the human environment, it's important to research the effects of buildings on their inhabitants. In order for environmental designers to act on feedback from situated use, designers need to have access to that feedback and all actors interacting with the building design need to have an easy, inexpensive, and accessible method to submit feedback. These needs can be addressed by utilizing modern networked and mobile computing to collect and access building feedback. The analysis presented in this dissertation is informed by a thorough evaluation of the theory of reflective practice, activity theory, environmental design, and cognitive science research. From this analysis, I developed the following contributions. First, I expanded Schon's reflective practice by combining his theory with a modified version of activity theory, using activity theory to enrich reflective practice and create Reflective Activity Systems Theory (RAST), which provides a new framework to develop design rationale based on feedback from use and a focus on the activity. Second, I suggest the design of an activity information system, Socio-Technical Environments for Evolutionary Design (STEED), which provides an interactive platform for actor and artifact feedback from the use situation. Third, I discuss implications for practice by discussing how the feedback from actors and artifacts in situated use can be used to create reflective design rationale.

Design of a Workstation by a Cognitive Approach

PubMed Central

Jaspers, MWM; Steen, T.; Geelen, M.; van den Bos, C.

2001-01-01

To ensure ultimate acceptance of computer systems that are easy to use, provide the desired functionality and fits into users work practices requires the use of improved methods for system design and evaluation. Both designing and evaluating workstations that link up smoothly with daily routine of physicians' work requires a thorough understanding of their working practices. The application of methods from cognitive science may contribute to a thorough understanding of the activities involved in medical information processing. We used cognitive task analysis in designing a physicians' workstation, which seems a promising method to ensure that the system meets the user needs.

Integrating Safety and Mission Assurance in Design

NASA Technical Reports Server (NTRS)

Cianciola, Chris; Crane, Kenneth

2008-01-01

This presentation describes how the Ares Projects are learning from the successes and failures of previous launch systems in order to maximize safety and reliability while maintaining fiscal responsibility. The Ares Projects are integrating Safety and Mission Assurance into design activities and embracing independent assessments by Quality experts in thorough reviews of designs and processes. Incorporating Lean thinking into the design process, Ares is also streamlining existing processes and future manufacturing flows which will yield savings during production. Understanding the value of early involvement of Quality experts, the Ares Projects are leading launch vehicle development into the 21st century.

Central Dog-ma Disease Detectives: A Molecular Biology Inquiry Activity for Undergraduates

NASA Astrophysics Data System (ADS)

Quan, T. K.; Yuh, P.; Black, F.

2010-12-01

The Minority Access to Research Careers (MARC) and Minority Biomedical Research Support (MBRS) are programs at the University of California at Santa Cruz designed to support minority undergraduate students majoring in the sciences. Each summer MARC/MBRS sponsors a Summer Institute that involves week long "rotations" with different faculty mentors. In 2008, the Center for Adaptive Optics (CfAO) Professional Development Program (PDP) was responsible for overseeing one week of the Summer Institute, and designed it to be a Biomedical Short Course. As part of this short course, we designed a four-hour activity in which students collected their own data and explored relationships between the basic biomolecules DNA, RNA, and protein. The goal was to have the students use experimental data to support their explanation of the "Central Dogma" of molecular biology. Here we describe details of our activity and provide a post-teaching reflection on its success.

Basic research and data analysis for the national geodetic satellite program and for the earth and ocean physics applications program

NASA Technical Reports Server (NTRS)

1974-01-01

Activities related to the National Geodetic Satellite Program are reported and include a discussion of Ohio State University's OSU275 set of tracking station coordinates and transformation parameters, determination of network distortions, and plans for data acquisition and processing. The problems encountered in the development of the LAGEOS satellite are reported in an account of activities related to the Earth and Ocean Physics Applications Program. The LAGEOS problem involves transmission and reception of the laser pulse designed to make accurate determinations of the earth's crustal and rotational motions. Pulse motion, ephemeris, arc range measurements, and accuracy estimates are discussed in view of the problem. Personnel involved in the two programs are also listed, along with travel activities and reports published to date.

Organizational member involvement in physical activity coalitions across the United States: development and testing of a novel survey instrument for assessing coalition functioning.

PubMed

Bornstein, Daniel B; Pate, Russell R; Beets, Michael W; Saunders, Ruth P; Blair, Steven N

2015-06-01

Coalitions are often composed of member organizations. Member involvement is thought to be associated with coalition success. No instrument currently exists for evaluating organizational member involvement in physical activity coalitions. This study aimed to develop a survey instrument for evaluating organizational member involvement in physical activity coalitions. The study was carried out in three phases: (a) developing a draft survey, (b) assessing the content validity of the draft survey, and (c) assessing the underlying factor structure, reliability, and validity of the survey. A cross-sectional design was employed. In Phase 1, a team of experts in survey development produced a draft survey. In Phase 2, the content validity of the draft survey was evaluated by a panel of individuals with expertise in physical activity coalitions. In Phase 3, the survey was administered to 120 individuals on local-, state-, and national-level physical activity coalitions. Responses were subjected to an exploratory factor analysis in order to determine the survey's underlying factor structure, reliability, and validity. Phases 1 and 2yielded a survey instrument with demonstrated content validity. Phase 3 yielded a three-factor model with three subscales: Strategic Alignment, Organizational Alignment, and Providing Input. Each subscale demonstrated high internal consistency reliability and construct validity. The survey instrument developed here demonstrated sound psychometric properties and provides new insight into organizational member involvement in physical activity coalitions. This instrument may be an important tool in developing a more complete picture of coalition functioning in physical activity coalitions specifically and health-based coalitions overall. © 2014 Society for Public Health Education.

An investigation into the protective factors for overweight among low socio-economic status children.

PubMed

Boshoff, Kobie; Dollman, Jim; Magarey, Anthea

2007-08-01

In light of the current obesity epidemic, this study aimed to expand the knowledge base about the factors involved and the characteristics of children of low socio-economic status (SES) who display healthy behaviours in their eating and physical activity. This project was conducted in two phases: a non-experimental, quantitative design was used in phase one to assess the characteristics of a sample of children in a low SES community. This phase identified children who displayed healthy eating and physical activity behaviours. Phase two used interpretive qualitative methods to investigate the perceptions of these children and their parents about the protective factors involved. Focus groups with children and interviews with their mothers were conducted. In phase one, 45 of 227 children assessed met a priori criteria set for healthy eating and physical activity behaviours. Central themes identified in phase two include: the influence of perceived health benefits; parental and child values regarding healthy eating and physical activity; the sense of enjoyment that children experience; the impact of child preferences and choice; and social influences. The study illustrated the complexity of factors involved in physical activity and healthy eating among children in a low socio-economic community.

Set. Research Information for Teachers. Number Two 1990.

ERIC Educational Resources Information Center

Jeffery, Peter, Ed.

This set of research materials incorporates information for teachers, principals, students, lecturers, and actively involved parents. Included are leaflets and brief reports designed for private study, staff meetings, inservice courses, or small group discussion. The package contains 15 research studies: "Modified Sports: Kiwi and…

28 CFR 33.32 - Certified programs.

Code of Federal Regulations, 2010 CFR

2010-07-01

... enable citizens and police to undertake initiatives to prevent and control neighborhood crime. (ii... by either law enforcement agencies or existing community groups, but each must have the active support and involvement of the other. Local programs must be designed to meet the needs and problems of...

Beyond Homework: Science and Mathematics Backpacks.

ERIC Educational Resources Information Center

Kokoski, Teresa M.; Patton, Mary Martin

1997-01-01

Describes classroom-developed science and mathematics backpacks, self-contained educational packets developed around a theme or concept and designed to be completed at home. Presents generalized contents, a sample backpack on colors, and the backpack's advantages, including promotion of active learning, family involvement, curriculum integration,…

A Multidimensional Software Engineering Course

ERIC Educational Resources Information Center

Barzilay, O.; Hazzan, O.; Yehudai, A.

2009-01-01

Software engineering (SE) is a multidimensional field that involves activities in various areas and disciplines, such as computer science, project management, and system engineering. Though modern SE curricula include designated courses that address these various subjects, an advanced summary course that synthesizes them is still missing. Such a…

Communication Disorders: An Individualized Program.

ERIC Educational Resources Information Center

Vodola, Thomas M.

As one of the components of the Project ACTIVE (All Children Totally Involved Exercising) Teacher Training Model Kit, the manual is designed to enable the educator to organize, conduct, and evaluate individualized-personalized programs for children (kindergarten through high school) with communication disorders. An introductory chapter covers…

A Selected, Annotated Bibliography for Fitness Educators.

ERIC Educational Resources Information Center

Whitehead, James R.

1992-01-01

This annotated bibliography, designed for practitioners and those involved in improving practice, contains 218 citations on topics related to youth physical fitness. Topics include children's fitness and activity status; contents of, and rationale for, fitness education; program suggestions, methods, and strategies; drug problems; and fitness…

Collaborative Instructional Strategies to Enhance Knowledge Convergence

ERIC Educational Resources Information Center

Draper, Darryl C.

2015-01-01

To promote knowledge convergence through collaborative learning activities in groups, this qualitative case study involved a layered approach for the design and delivery of a highly collaborative learning environment incorporating various instructional technologies grounded in learning theory. In a graduate-level instructional technology course,…

9 CFR 71.1 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-01-01

... § 79.6 of this subchapter, for conducting an active State scrapie program involving the identification... shield. Beginning March 11, 2015, all official eartags applied to animals must bear an official eartag shield. The design, size, shape, color, and other characteristics of the official eartag will depend on...

76 FR 80901 - Agency Information Collection Activities Under OMB Review

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-27

... monitoring legal proceedings involving the responsibilities imposed on contract markets and their officials... avoid fraud and misrepresentations. In addition, the Commission's rules impose obligations on contract markets that are designed to avoid manipulation and fraud. In order to ensure compliance with these rules...

The Pasta Paradigm.

ERIC Educational Resources Information Center

Sconyers, Jim

1997-01-01

Describes an activity that focuses on the question: How hard is it to break spaghetti noodles? Students design their own experiment that involves hanging a cup of pennies from a piece of spaghetti by a paper clip and investigate how many pennies the noodle can support without breaking. (DDR)

Vectors and Fomites: An Investigative Laboratory for Undergraduates.

ERIC Educational Resources Information Center

Adamo, Joseph A.; Gealt, Michael A.

1996-01-01

Presents a laboratory model system for introductory microbiology students that involves hands-on studies of bacteria vectored in soil nematodes. Describes a series of experiments designed to demonstrate vector-fomite transmission, bacterial survival, and disinfectant activity. Introduces the concept of genetically engineered microorganisms and the…

Working Model Hearts

ERIC Educational Resources Information Center

Brock, David

2009-01-01

Despite student interest, the heart is often a poorly understood topic in biology. To help students understand this vital organ's physiology, the author created this investigation activity involving the mammalian heart and its role in the circulatory system. Students design, build, and demonstrate working artificial "hearts" to exhibit what they…

Introduction to Psychology.

ERIC Educational Resources Information Center

Edwards, Lesley

Designed for community students interested in learning about psychology as a field of study, this module offers group and individual activities to involve the beginning student in research, experimentation and discussion. Unit 1, "What Is Psychology?," includes the use of animals in psychology, ethics, the history of psychology, an…

VETPOP2001 ADJ

EPA Science Inventory

VetPop2001Adj is VA's new official estimate and projection of the veteran population as of 9-30-02. It revises and replaces the estimate and projection in VetPop2001. Mathematica has been actively involved since 1998 in designing and developing an actuarial model, VetPop2001 that...

Meals, Mindfulness, & Moving Forward: A feasibility study to a multi-modal lifestyle approach in early psychosis.

PubMed

Usher, Craigan; Thompson, Andie; Griebeler, Meridith; Senders, Angela; Seibel, Celeste; Ly, Richard; Murchison, Charles; Hagen, Kirsten; Afong, Keith-Allen; Bourdette, Dennis; Ross, Rachel; Borgatti, Alena; Shinto, Lynne

2018-03-07

The primary aim was to demonstrate adherence to a novel 6-week lifestyle intervention program ("Meals, Mindfulness, & Moving Forward" [M 3 ]) designed to help improve lifestyle practices of youth with a history of at least 1 psychotic episode. M 3 used a non-equivalent control group design involving clients from a community early intervention program. Seventeen individuals in the active M 3 program and 16 controls were assessed for secondary outcomes at baseline, 6-weeks, and 12-weeks (6 weeks post-intervention) on cardiometabolic and symptomatic outcomes. The program met its primary aim with 88% (15/17) of participants meeting adherence criteria. Compared with the controls, M 3 participants showed significant improvement in positive psychotic symptoms (P = .002). This pilot study showed that young people involved in a community early intervention program adhered to an activity-based lifestyle program which included mindfulness meditation, yoga and nutrition education, warranting further evaluation with a larger sample size. © 2018 John Wiley & Sons Australia, Ltd.

Bilinguals Use Language-Control Brain Areas More Than Monolinguals to Perform Non-Linguistic Switching Tasks

PubMed Central

Rodríguez-Pujadas, Aina; Sanjuán, Ana; Ventura-Campos, Noelia; Román, Patricia; Martin, Clara; Barceló, Francisco; Costa, Albert; Ávila, César

2013-01-01

We tested the hypothesis that early bilinguals use language-control brain areas more than monolinguals when performing non-linguistic executive control tasks. We do so by exploring the brain activity of early bilinguals and monolinguals in a task-switching paradigm using an embedded critical trial design. Crucially, the task was designed such that the behavioural performance of the two groups was comparable, allowing then to have a safer comparison between the corresponding brain activity in the two groups. Despite the lack of behavioural differences between both groups, early bilinguals used language-control areas – such as left caudate, and left inferior and middle frontal gyri – more than monolinguals, when performing the switching task. Results offer direct support for the notion that, early bilingualism exerts an effect in the neural circuitry responsible for executive control. This effect partially involves the recruitment of brain areas involved in language control when performing domain-general executive control tasks, highlighting the cross-talk between these two domains. PMID:24058456

The Neural Correlates of Self-Regulatory Fatigability During Inhibitory Control of Eye Blinking.

PubMed

Abi-Jaoude, Elia; Segura, Barbara; Cho, Sang Soo; Crawley, Adrian; Sandor, Paul

2018-05-30

The capacity to regulate urges is an important human characteristic associated with a range of social and health outcomes. Self-regulatory capacity has been postulated to have a limited reserve, which when depleted leads to failure. The authors aimed to investigate the neural correlates of self-regulatory fatigability. Functional MRI was used to detect brain activations in 19 right-handed healthy subjects during inhibition of eye blinking, in a block design. The increase in number of blinks during blink inhibition from the first to the last block was used as covariate of interest. There was an increase in the number of eye blinks escaping inhibitory control across blink inhibition blocks, whereas there was no change in the number of eye blinks occurring during rest blocks. Inhibition of blinking activated a wide network bilaterally, including the inferior frontal gyrus, dorsolateral prefrontal cortex, dorsal anterior cingulate cortex, supplementary motor area, and caudate. Deteriorating performance was associated with activity in orbitofrontal cortex, ventromedial prefrontal cortex, rostroventral anterior cingulate cortex, precuneus, somatosensory, and parietal areas. As anticipated, effortful eye-blink control resulted in activation of prefrontal control areas and regions involved in urge and interoceptive processing. Worsening performance was associated with activations in brain areas involved in urge, as well as regions involved in motivational evaluation. These findings suggest that self-regulatory fatigability is associated with relatively less recruitment of prefrontal cortical regions involved in executive control.

Computer-Aided Environmental Impact Analysis for Industrial, Procurement, and Research, Development, Test, and Evaluation Activities: User Manual.

DTIC Science & Technology

1978-06-01

Oxygen Demand , Phosphorus , Army activities, or BAAPs (Basic Activities to Imple- and Mercury ; and in Sociology : Population Composi- ment Army Programs...wide) involved? minerals with a proved world reserve (in 1975) of 10 to 15 years are mercury and silver; from 15 to 20years , • What are the energy...antidotes and detox - 128 Forecast. Development of predictions or models ifiers). Design fnethods for interfering with delivery of of present and

Scrutinizing UML Activity Diagrams

NASA Astrophysics Data System (ADS)

Al-Fedaghi, Sabah

Building an information system involves two processes: conceptual modeling of the “real world domain” and designing the software system. Object-oriented methods and languages (e.g., UML) are typically used for describing the software system. For the system analysis process that produces the conceptual description, object-oriented techniques or semantics extensions are utilized. Specifically, UML activity diagrams are the “flow charts” of object-oriented conceptualization tools. This chapter proposes an alternative to UML activity diagrams through the development of a conceptual modeling methodology based on the notion of flow.

Design, Implementation and Impact of the MS PHD’S Professional Development Program

NASA Astrophysics Data System (ADS)

Williamson Whitney, V.

2009-12-01

The Minorities Striving and Pursuing Higher Degrees of Success (MS PHD'S)® in Earth System Science initiative facilitates the involvement of underrepresented minority undergraduate and graduate Earth system science students in a series of activities designed to: (1) increase exposure to and engagement in the Earth system science community, via participation in scientific conferences, mentoring relationships, virtual activities, and field trips; (2) enhance professional skills, grantsmanship, oral and written communication; (3) provide funding, education and career opportunity resources; (4) facilitate networking opportunities with established researchers and educators; (5) and sustain on-going interaction, communication and support via membership within a virtual community comprised of peers, junior/senior-level researchers, and educators actively involved in facilitating full participation of minorities in the Earth system sciences. These activities, conducted in three phases, occur during professional society meetings, field trips, visits to several federal agencies, and a 'capstone' event at the National Academies. Nearly 150 Earth system science undergraduate, graduate and recent minority graduates have participated in MS PHD’S activities and are better prepared to successfully achieve their academic and professional goals. It is also expected that because of mentor-mentee partnerships, science exposure, and networking activities, MS PHD'S participants will remain actively engaged in their fields of specialization and respective professional societies. Evaluation data for MS PHD’S activities indicate that virtual and face-to-face mentoring, on-site professional development and community-building activities resulted in increased participant exposure to and engagement in the Earth system science professional community and served to better equip student participants to make informed post-baccalaureate academic and professional career decisions.

Evaluation of a course designed to teach physics to students of physiotherapy

NASA Astrophysics Data System (ADS)

Simpson, Ian A.; Singer, Kevin P.; Treagust, David; Zadnik, Marjan G.

1990-01-01

This paper describes the development and evaluation of a course in physiotherapy whereby the physics fundamental to the modalities of cold, heat and ultrasound therapies was integrated in lectures and actual physiotherapy activities. The design of the course is described together with the perceptions of physiotherapy students regarding the organisation of the course, safety aspects and how well the integration contributed to their understanding of the physics involved in electrotherapy.

Natural Environments Definition for Design

NASA Technical Reports Server (NTRS)

Justh, H. L.; Altino, K. M.; Decker, R. K.; Koehler, H. M.; Leahy, F. B.; Minow, J. I.; Roberts, B. C.; Suggs, R. M.; Suggs, R. J.; White, P. W.;

Automated Methodologies for the Design of Flow Diagrams for Development and Maintenance Activities

NASA Astrophysics Data System (ADS)

Shivanand M., Handigund; Shweta, Bhat

The Software Requirements Specification (SRS) of the organization is a text document prepared by strategic management incorporating the requirements of the organization. These requirements of ongoing business/ project development process involve the software tools, the hardware devices, the manual procedures, the application programs and the communication commands. These components are appropriately ordered for achieving the mission of the concerned process both in the project development and the ongoing business processes, in different flow diagrams viz. activity chart, workflow diagram, activity diagram, component diagram and deployment diagram. This paper proposes two generic, automatic methodologies for the design of various flow diagrams of (i) project development activities, (ii) ongoing business process. The methodologies also resolve the ensuing deadlocks in the flow diagrams and determine the critical paths for the activity chart. Though both methodologies are independent, each complements other in authenticating its correctness and completeness.

Introducing patient perspective in health technology assessment at the local level

PubMed Central

Gagnon, Marie-Pierre; Lepage-Savary, Dolorès; Gagnon, Johanne; St-Pierre, Michèle; Simard, Chantale; Rhainds, Marc; Lemieux, Renald; Gauvin, François-Pierre; Desmartis, Marie; Légaré, France

2009-01-01

Background Recognizing the importance of increased patient participation in healthcare decisions leads decision makers to consider effective ways to incorporate patient perspectives in Health Technology Assessment (HTA) processes. The implementation of local health HTA units in university hospitals in Quebec provides a unique opportunity to foster an increased participation of patients in decisions regarding health technologies and clinical interventions. This project explores strategies that could be effective in involving patients in HTA activities at the local level. To do so, three objectives are pursued: 1) To synthesise international knowledge and experiences on patient and public involvement in HTA activities; 2) To explore the perceptions of stakeholders (administrators, clinical managers, healthcare professionals, HTA producers, and patients) regarding strategies for involving patients in various HTA activities; and 3) To produce a consensual strategic framework that could guide interventions for involving patients in HTA activities at the local level. Methods A systematic review of the literature will be conducted to synthesise international knowledge and experiments regarding the implication of patients and public in HTA. Then, focus groups will be carried out with representatives of various stakeholder groups in order to explore their perceptions regarding patient participation in HTA. Based on findings from the systematic review and the focus groups, a framework to support patient participation in HTA activities will be proposed. It will then be validated during a deliberative meeting with the research team, composed of scientists and decision makers, and representatives from different groups involved in HTA in Quebec. This deliberative meeting will aim at identifying the type and the degree of participation as well as the adequate timing for involving patients in local HTA activities. Discussion Given the actual state of evidence, integrating patient perspective in HTA activities has the potential to improve the quality of healthcare services. This study provides an opportunity to bridge the gap between HTA producers and its ultimate end-user: the patient. It will provide guidance to support local HTA units in Quebec and elsewhere in their decisions regarding patient participation. The framework developed could be applied to design and implement strategies for involving patients in HTA activities. PMID:19327160

Engineering and Design: Chemical Data Quality Management for Hazardous, Toxic, Radioactive Waste Remedial Activities

DTIC Science & Technology

This regulation prescribes Chemical Data Quality Management (CDQM) responsibilities and procedures for projects involving hazardous, toxic and/or radioactive waste (HTRW) materials. Its purpose is to assure that the analytical data meet project data quality objectives. This is the umbrella regulation that defines CDQM activities and integrates all of the other U.S. Army Corps of Engineers (USACE) guidance on environmental data quality management .

European Science Notes Information Bulletin Reports on Current European/ Middle Eastern Science

DTIC Science & Technology

1990-01-01

because they permit a high degree of error then converted into system-specific data by coupling tolerance. Other knowledge- based approaches offer the...Reducing development costs and development time ing an increasingly powerful focus for business activities . " Simplifying the design process In the...systems. Sie- The immediate goal of telecommunications efforts is a mens is actively involved in defining and implementing configuration based on ISDN and

The Family Science Starter Kit: A Manual To Assist You in the Development of a Family Aeronautical Science Program. UNOAI Report.

ERIC Educational Resources Information Center

Lehrer, Henry R.

This book is designed to involve families working together on several different hands-on activities during evening meetings at school. The basis for these activities is the in-school study of related science and mathematical concepts and topics by the students in each family. The program provides an opportunity for families to work together in an…

The farm apprentice: agricultural college students recollections of learning to farm "safely".

PubMed

Sanderson, L L; Dukeshire, S R; Rangel, C; Garbes, R

2010-10-01

A consistent message in the farm safety literature is the need to develop effective interventions to manage the unacceptably high rate of injury and death among farm children. To better understand the influence of childhood farm experiences on safety beliefs, attitudes, and practices, semi-structured interviews were conducted with 24 farm youth attending the Nova Scotia Agricultural College. The interviews were designed to elicit information pertaining to participants' earliest memories of involvement in farm activities, the decision-making processes that led them to assume work-related responsibilities, and the roles that their parents played in their safety training. A common theme of experiencing childhood as a "farm apprentice" emerged across all narratives whereby farm activities were learned primarily through observational learning and modeling of parents and then mastered through repetition. As "farm apprentices," the youths' involvement in dangerous activities such as tractor driving and livestock handling began at early ages, with very little formal training and supervision. Although participants clearly described themselves as being exposed to dangerous activities, they believed that they had the capacity to control the risks and farm safely. Based on our findings, the concept of the "farm apprentice" appears to be integral to the social context of the farming community and should be considered in the design of interventions to reduce child injury and death.

Design, Synthesis and in vitro Biochemical Activity of Novel Amino Acid Sulfonohydrazide Inhibitors of MurC.

PubMed

Frlan, Rok; Kovač, Andreja; Blanot, Didier; Gobec, Stanislav; Pečar, Slavko; Obreza, Aleš

2011-06-01

Mur ligases are essential enzymes involved in the cytoplasmic steps of peptidoglycan synthesis which remain attractive, yet unexploited targets. In order to develop new antibacterial agents, we have designed a series of new MurC and MurD inhibitors bearing amino acid sulfonohydrazide moiety. The L-Leu series of this class displayed the highest enzyme inhibition with IC50 in the concentration range between 100 and 500 µM, with L-Thr, L-Pro and L-Ala derivatives being inactive. The most promising compound of the series also expressed weak antibacterial activity against S. aureus with MIC = 128 µg/mL.

Modeling strength data for CREW CHIEF

NASA Technical Reports Server (NTRS)

Mcdaniel, Joe W.

1990-01-01

The Air Force has developed CREW CHIEF, a computer-aided design (CAD) tool for simulating and evaluating aircraft maintenance to determine if the required activities are feasible. CREW CHIEF gives the designer the ability to simulate maintenance activities with respect to reach, accessibility, strength, hand tool operation, and materials handling. While developing the CREW CHIEF, extensive research was performed to describe workers strength capabilities for using hand tools and manual handling of objects. More than 100,000 strength measures were collected and modeled for CREW CHIEF. These measures involved both male and female subjects in the 12 maintenance postures included in CREW CHIEF. The data collection and modeling effort are described.

ICAN Computer Code Adapted for Building Materials

NASA Technical Reports Server (NTRS)

Murthy, Pappu L. N.

1997-01-01

The NASA Lewis Research Center has been involved in developing composite micromechanics and macromechanics theories over the last three decades. These activities have resulted in several composite mechanics theories and structural analysis codes whose applications range from material behavior design and analysis to structural component response. One of these computer codes, the Integrated Composite Analyzer (ICAN), is designed primarily to address issues related to designing polymer matrix composites and predicting their properties - including hygral, thermal, and mechanical load effects. Recently, under a cost-sharing cooperative agreement with a Fortune 500 corporation, Master Builders Inc., ICAN was adapted to analyze building materials. The high costs and technical difficulties involved with the fabrication of continuous-fiber-reinforced composites sometimes limit their use. Particulate-reinforced composites can be thought of as a viable alternative. They are as easily processed to near-net shape as monolithic materials, yet have the improved stiffness, strength, and fracture toughness that is characteristic of continuous-fiber-reinforced composites. For example, particlereinforced metal-matrix composites show great potential for a variety of automotive applications, such as disk brake rotors, connecting rods, cylinder liners, and other hightemperature applications. Building materials, such as concrete, can be thought of as one of the oldest materials in this category of multiphase, particle-reinforced materials. The adaptation of ICAN to analyze particle-reinforced composite materials involved the development of new micromechanics-based theories. A derivative of the ICAN code, ICAN/PART, was developed and delivered to Master Builders Inc. as a part of the cooperative activity.

Cognitive Inference Device for Activity Supervision in the Elderly

PubMed Central

2014-01-01

Human activity, life span, and quality of life are enhanced by innovations in science and technology. Aging individual needs to take advantage of these developments to lead a self-regulated life. However, maintaining a self-regulated life at old age involves a high degree of risk, and the elderly often fail at this goal. Thus, the objective of our study is to investigate the feasibility of implementing a cognitive inference device (CI-device) for effective activity supervision in the elderly. To frame the CI-device, we propose a device design framework along with an inference algorithm and implement the designs through an artificial neural model with different configurations, mapping the CI-device's functions to minimise the device's prediction error. An analysis and discussion are then provided to validate the feasibility of CI-device implementation for activity supervision in the elderly. PMID:25405211

Active Involvement of End Users When Developing Web-Based Mental Health Interventions.

PubMed

de Beurs, Derek; van Bruinessen, Inge; Noordman, Janneke; Friele, Roland; van Dulmen, Sandra

2017-01-01

Although many web-based mental health interventions are being released, the actual uptake by end users is limited. The marginal level of engagement of end users when developing these interventions is recognized as an important cause for uptake problems. In this paper, we offer our perceptive on how to improve user engagement. By doing so, we aim to stimulate a discourse on user involvement within the field of online mental health interventions. We shortly describe three different methods (the expert-driven method, intervention mapping, and scrum) that were currently used to develop web-based health interventions. We will focus to what extent the end user was involved in the developmental phase, and what the additional challenges were. In the final paragraph, lessons learned are summarized, and recommendations provided. Every method seems to have its trade-off: if end users are highly involved, availability of end users and means become problematic. If end users are less actively involved, the product may be less appropriate for the end user. Other challenges to consider are the funding of the more active role of technological companies, and the time it takes to process the results of shorter development cycles. Thinking about user-centered design and carefully planning, the involvement of end users should become standard in the field of web-based (mental) health. When deciding on the level of user involvement, one should balance the need for input from users with the availability of resources such as time and funding.

Wearable activity monitors in oncology trials: Current use of an emerging technology.

PubMed

Gresham, Gillian; Schrack, Jennifer; Gresham, Louise M; Shinde, Arvind M; Hendifar, Andrew E; Tuli, Richard; Rimel, B J; Figlin, Robert; Meinert, Curtis L; Piantadosi, Steven

2018-01-01

Physical activity is an important outcome in oncology trials. Physical activity is commonly assessed using self-reported questionnaires, which are limited by recall and response biases. Recent advancements in wearable technology have provided oncologists with new opportunities to obtain real-time, objective physical activity data. The purpose of this review was to describe current uses of wearable activity monitors in oncology trials. We searched Pubmed, Embase, and the Cochrane Central Register of Controlled Trials for oncology trials involving wearable activity monitors published between 2005 and 2016. We extracted details on study design, types of activity monitors used, and purpose for their use. We summarized activity monitor metrics including step counts, sleep and sedentary time, and time spent in moderate-to-vigorous activity. We identified 41 trials of which 26 (63%) involved cancer survivors (post-treatment) and 15 trials (37%) involved patients with active cancer. Most trials (65%) involved breast cancer patients. Wearable activity monitors were commonly used in exercise (54%) or behavioral (29%) trials. Cancer survivors take between 4660 and 11,000 steps/day and those undergoing treatment take 2885 to 8300steps/day. Wearable activity monitors are increasingly being used to obtain objective measures of physical activity in oncology trials. There is potential for their use to expand to evaluate and predict clinical outcomes such as survival, quality of life, and treatment tolerance in future studies. Currently, there remains a lack of standardization in the types of monitors being used and how their data are being collected, analyzed, and interpreted. Recent advancements in wearable activity monitor technology have provided oncologists with new opportunities to monitor their patients' daily activity in real-world settings. The integration of wearable activity monitors into cancer care will help increase our understanding of the associations between physical activity and the prevention and management of the disease, in addition to other important cancer outcomes. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

Development and testing of a high cycle life 30 A-h sealed AgO-Zn battery

NASA Technical Reports Server (NTRS)

Bogner, R. S.

1972-01-01

A two-phase program was initiated to investigate design parameters and technology to develop an improved AgO-Zn battery. The basic performance goal was 100 charge/discharge cycles (22 h/2 h) at 50 percent depth of discharge following a six-month period of charged stand at room temperature. Phase 1, cell evaluation, involved testing 70 cells in five-cell groups. The major design variables were active material ratios, electrolyte concentrations, separator systems, and negative plate shape. Phase 1 testing showed that cycle life could be improved 10 percent to 20 percent by using greater ratios of zinc to silver oxide and higher electrolyte concentrations. Wedge-shaped negatives increased cycle life by nearly 100 percent. Phase 2 battery evaluation, which was initiated before the Phase 1 results were known completely, involved evaluation of six designs as 19-cell batteries. Only one battery exceeded 100 cycles following nine months charged stand.

Relevance of P-glycoprotein on CXCR4+ B cells to organ manifestation in highly active rheumatoid arthritis.

PubMed

Tsujimura, Shizuyo; Adachi, Tomoko; Saito, Kazuyoshi; Kawabe, Akio; Tanaka, Yoshiya

2018-03-01

In rheumatoid arthritis (RA), P-glycoprotein (P-gp) expression on activated B cells is associated with active efflux of intracellular drugs, resulting in drug resistance. CXCR4 is associated with migration of B cells. This study was designed to elucidate the relevance of P-gp expression on CXCR4 + B cells to clinical manifestations in refractory RA. CD19 + B cells were analyzed using flow cytometry and immunohistochemistry. P-gp was highly expressed especially on CXCR4 + CD19 + B cells in RA. The proportion of P-gp-expressing CXCR4 + B cells correlated with disease activity, estimated by Simplified Disease Activity Index (SDAI), and showed marked expansion in RA patients with high SDAI and extra-articular involvement. In highly active RA, massive infiltration of P-gp + CXCR4 + CD19 + B cells was noted in CXCL12-expressing inflammatory lesions of RA synovitis and RA-associated interstitial pneumonitis. In RA patient with active extra-articular involvement, intracellular dexamethasone level (IDL) in lymphocytes diminished with expansion of P-gp + CXCR4 + CD19 + B cells. Adalimumab reduced P-gp + CXCR4 + CD19 + B cells, increased IDL in lymphocytes, and improved the clinical manifestation and allowed tapering of concomitant medications. Expansion of P-gp + CXCR4 + B cells seems to be associated with drug resistance, disease activity and progressive destructive arthritis with extra-articular involvement in RA.

Summary of Research

DTIC Science & Technology

1993-10-01

Department .......................... .............................. 113 Language Studies Department...seventh year, in which the researcher has been reporting period, work was conducted in ihc design actively involved. This area i. ditinct from other study ...proposal concerns the study of oscillating wings without flaps demonstrate the hydrodynamic performance of a high aspect-ratio impotance of the

Try This: Construct a Water Catchment

ERIC Educational Resources Information Center

Teaching Science, 2017

2017-01-01

EngQuest, an initiative of Engineers Australia, provides an exciting, non-competitive way for students to participate in free, fun and educational engineering activities involving mathematics, science and technology. This article describes a project designed to teach middle school students how to construct a water catchment system. Water…

A Classroom Learning Cycle: Using Diagrams to Classify Matter.

ERIC Educational Resources Information Center

James, Helen J.; Nelson, Samuel L.

1981-01-01

A learning cycle involves the active participation of students in exploration, invention, and application phases. Describes one such learning cycle dealing with classification of matter and designed to provide students with an understanding of the terms: atom, molecule, element, compound, solution, and heterogeneous matter. (Author/JN)

Teacher's Guide, Ecology, Grade 7.

ERIC Educational Resources Information Center

Yadkin Valley Economic Development District, Inc., Walnut Cove, NC.

This teacher's guide has been constructed to assist in developing and implementing a life science course with an environment/ecological unit for Grade 7. Designed primarily for use with other science units, it offers numerous multidisciplinary activities which emphasize involvement in problem-solving through open-ended investigation rather than…

32 CFR 651.33 - Actions normally requiring an EA.

Code of Federal Regulations, 2011 CFR

2011-07-01

... for the use of a CX: (a) Special field training exercises or test activities in excess of five acres... off-post construction. (c) Changes to established installation land use that generate impacts on the..., fielding, and training involving natural resources, and disposal/demilitarization. System design...

Cattails or Concrete?

ERIC Educational Resources Information Center

Heal, Fred A.; And Others

Developed for elementary science studies, this unit on man and environment requires student involvement in discovery, observation, gathering and recording data, and problem solving. A series of 19 booklets, each designed as an activity which can be completed out-of-doors, comprise this student packet of materials. Topics studied in the activities…

Using the Microcomputer to Study the Anatomy of Revolution.

ERIC Educational Resources Information Center

Rothman, Mark

1982-01-01

Describes computer program designed to enable students to analyze process of political revolution by generating graphs for comparisons of such factors as violence, economic instability, and political instability. Student activities, abilities, and reactions, and teacher involvement are noted. Sources concerning revolution, the French Revolution,…

Rebels with a Cause.

ERIC Educational Resources Information Center

Rosenberg, Steve; McKeon, Loren Marie

1998-01-01

Describes the activities and benefits of Positive Peer Groups (PPG), a Cleveland-based diocese program involving 40 schools. Designed for students with behavioral or academic problems, it focuses on school service projects that teach students to develop and implement valuable social skills. Describes the positive social and academic effects PPG…

The Future is Now: OpenTERRAworks - Interoperable 2D/3D Landscape Design Software for Integrated Environmental Modeling

EPA Science Inventory

Human activities involving significant terrain alteration (e.g., earthworks operations associated with mines, urban development, landslides) can lead to broad-ranging changes in the surrounding terrestrial and aquatic environments. Potential aesthetic impacts can be associated wi...

Understanding Our Environment: Air.

ERIC Educational Resources Information Center

DiSpezio, Michael

Part of the Understanding Our Environment project that is designed to engage students in investigating specific environmental problems through concrete activities and direct experience, this unit uses the contemporary dilemma of acid rain as a vehicle for teaching weather and the characteristics of air and atmosphere. The project involves a…

Developing an Experiential Learning Program: Milestones and Challenges

ERIC Educational Resources Information Center

Austin, M. Jill; Rust, Dianna Zeh

2015-01-01

College and University faculty members have increasingly adopted experiential learning teaching methods that are designed to engage students in the learning process. Experiential learning is simply defined as "hands-on" learning and may involve any of the following activities: service learning, applied learning in the discipline,…

Teacher's Guide, Ecology, Grade 10.

ERIC Educational Resources Information Center

Yadkin Valley Economic Development District, Inc., Walnut Cove, NC.

This teacher's guide has been constructed to assist in developing and implementing a life science course with an environment/ecological unit for Grade 10. Designed primarily for use with other science units, it offers numerous multidisciplinary activities which emphasize involvement in problem-solving through open-ended investigation rather than…

46 CFR 221.11 - Required approvals.

Code of Federal Regulations, 2010 CFR

2010-10-01

... operated, if the vessel has been designed and built and will be operated for one or more of the following... ACTIVITIES REGULATED TRANSACTIONS INVOLVING DOCUMENTED VESSELS AND OTHER MARITIME INTERESTS Transfers to... approval of the Maritime Administrator: (1) Sell, lease, charter, deliver, or in any manner Transfer to a...

Resource Recovery. Energy and Environment. Teacher's Aid.

ERIC Educational Resources Information Center

Reynolds, Smith and Hills, Inc., Jacksonville, FL.

Designed to assist students in understanding solid waste resource recovery, this teaching aid package aims to get students involved in practical activities that require participation, observation, and interpretation. Provided in this package are definitions, methods, causes and effects, costs, and benefits of resource recovery presented in the…

Set. Research Information for Teachers. Number One 1991.

ERIC Educational Resources Information Center

Jeffery, Peter, Ed.

This set of materials incorporates research information for everyone interested in education: teachers, administrators, students, lecturers, and actively involved parents. Included are leaflets and brief reports designed for a quick read, private study, staff meetings, in-service courses, or small group discussions. This package contains 14…

49 CFR 98.6 - Examiner.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 1 2014-10-01 2014-10-01 false Examiner. 98.6 Section 98.6 Transportation Office of the Secretary of Transportation ENFORCEMENT OF RESTRICTIONS ON POST-EMPLOYMENT ACTIVITIES...”) shall be designated by the Secretary. (b) The examiner shall not have been involved in any of the events...

49 CFR 98.6 - Examiner.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 1 2012-10-01 2012-10-01 false Examiner. 98.6 Section 98.6 Transportation Office of the Secretary of Transportation ENFORCEMENT OF RESTRICTIONS ON POST-EMPLOYMENT ACTIVITIES...”) shall be designated by the Secretary. (b) The examiner shall not have been involved in any of the events...

49 CFR 98.6 - Examiner.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 1 2013-10-01 2013-10-01 false Examiner. 98.6 Section 98.6 Transportation Office of the Secretary of Transportation ENFORCEMENT OF RESTRICTIONS ON POST-EMPLOYMENT ACTIVITIES...”) shall be designated by the Secretary. (b) The examiner shall not have been involved in any of the events...

49 CFR 98.6 - Examiner.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 1 2010-10-01 2010-10-01 false Examiner. 98.6 Section 98.6 Transportation Office of the Secretary of Transportation ENFORCEMENT OF RESTRICTIONS ON POST-EMPLOYMENT ACTIVITIES...”) shall be designated by the Secretary. (b) The examiner shall not have been involved in any of the events...

49 CFR 98.6 - Examiner.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 1 2011-10-01 2011-10-01 false Examiner. 98.6 Section 98.6 Transportation Office of the Secretary of Transportation ENFORCEMENT OF RESTRICTIONS ON POST-EMPLOYMENT ACTIVITIES...”) shall be designated by the Secretary. (b) The examiner shall not have been involved in any of the events...

Student-Created Digital Media and Engagement in Middle School History

ERIC Educational Resources Information Center

Alexander, Curby

2014-01-01

In this study, student engagement during classroom activities was investigated where sixth graders created digital media projects using historical images. The study employed a qualitative design involving observations, student artifacts, and interviews while students were creating digital storyboards using a Web-based application developed for…

Read with a Beat: Developing Literacy through Music and Song (Teaching Reading).

ERIC Educational Resources Information Center

Kolb, Gayla R.

1996-01-01

Argues that the singing-reading connective helps children learn to read and fosters a love for reading. Discusses integrating music with reading and notes various activities designed to extend the singing-reading experience, involving book concepts, sight vocabulary, reading comprehension, and fluency. (SR)

Confronting Challenges in Intervention Research with Ethnically Diverse Older Adults: The USC Well Elderly II Trial

PubMed Central

Jackson, Jeanne; Mandel, Deborah; Blanchard, Jeanine; Carlson, Mike; Cherry, Barbara; Azen, Stanley; Chou, Chih-Ping; Jordan-Marsh, Maryalice; Forman, Todd; White, Brett; Granger, Douglas; Knight, Bob; Clark, Florence

2011-01-01

Background Community-dwelling older adults are at risk for declines in physical health, cognition, and psychosocial well-being. However, their enactment of active and health-promoting lifestyles can reduce such declines. Purpose The purpose of this article is to describe the USC Well Elderly II study, a randomized clinical trial designed to test the effectiveness of a healthy lifestyle program for elders, and document how various methodological challenges were addressed during the course of the trial. Methods In the study, 460 ethnically diverse elders recruited from a variety of sites in the urban Los Angeles area were enrolled in a randomized experiment involving a crossover design component. Within either the first or second six month phase of their study involvement, each elder received a lifestyle intervention designed to improve a variety of aging outcomes. At 4–5 time points over an 18–24 month interval, the research participants were assessed on measures of healthy activity, coping, social support, perceived control, stress-related biomarkers, perceived physical health, psychosocial well-being, and cognitive functioning to test the effectiveness of the intervention and document the process mechanisms responsible for its effects. Results The study protocol was successfully implemented, including the enrollment of study sites, the recruitment of 460 older adults, administration of the intervention, adherence to the plan for assessment, and establishment of a large computerized data base. Limitations Methodological challenges were encountered in the areas of site recruitment, participant recruitment, testing, and intervention delivery. Conclusions The completion of clinical trials involving elders from numerous local sites requires careful oversight and anticipation of threats to the study design that stem from: (a) social situations that are particular to specific study sites; and (b) physical, functional, and social challenges pertaining to the elder population. PMID:19254939

Confronting challenges in intervention research with ethnically diverse older adults: the USC Well Elderly II Trial.

PubMed

Jackson, Jeanne; Mandel, Deborah; Blanchard, Jeanine; Carlson, Mike; Cherry, Barbara; Azen, Stanley; Chou, Chih-Ping; Jordan-Marsh, Maryalice; Forman, Todd; White, Brett; Granger, Douglas; Knight, Bob; Clark, Florence

2009-02-01

Community-dwelling older adults are at risk for declines in physical health, cognition, and psychosocial well-being. However, their enactment of active and health-promoting lifestyles can reduce such declines. The purpose of this article is to describe the USC Well Elderly II study, a randomized clinical trial designed to test the effectiveness of a healthy lifestyle program for elders, and document how various methodological challenges were addressed during the course of the trial. In the study, 460 ethnically diverse elders recruited from a variety of sites in the urban Los Angeles area were enrolled in a randomized experiment involving a crossover design component. Within either the first or second 6-month phase of their study involvement, each elder received a lifestyle intervention designed to improve a variety of aging outcomes. At 4-5 time points over an 18-24 month interval, the research participants were assessed on measures of healthy activity, coping, social support, perceived control, stress-related biomarkers, perceived physical health, psychosocial well-being, and cognitive functioning to test the effectiveness of the intervention and document the process mechanisms responsible for its effects. The study protocol was successfully implemented, including the enrollment of study sites, the recruitment of 460 older adults, administration of the intervention, adherence to the plan for assessment, and establishment of a large computerized data base. Methodological challenges were encountered in the areas of site recruitment, participant recruitment, testing, and intervention delivery. The completion of clinical trials involving elders from numerous local sites requires careful oversight and anticipation of threats to the study design that stem from: (a) social situations that are particular to specific study sites; and (b) physical, functional, and social challenges pertaining to the elder population.

Models to support students’ understanding of measuring area of circles

NASA Astrophysics Data System (ADS)

Rejeki, S.; Putri, R. I. I.

2018-01-01

Many studies showed that enormous students got confused about the concepts of measuring area of circles. The main reason is because mathematics classroom practices emphasized on memorizing formulas rather than understanding concepts. Therefore, in this study, a set of learning activities were designed as an innovation in learning area measurement of circles. The activities involved two models namely grid paper and reshaping which are respectively as a means and a strategy to support students’ learning of area measurement of circles. Design research was used as the research approach to achieve the aim. Thirty-eight of 8th graders in Indonesia were involved in this study. In this study, together with the contextual problems, the grid paper and reshaping sectors, which used as the models in this learning, helped the students to gradually develop their understanding of the area measurement of circles. The grid papers plays important role in comparing and estimating areas. Whereas, the reshaping sectors might support students’ understanding of the circumference and the area measurement of circles. Those two models could be the tool for promoting the informal theory of area measurement. Besides, the whole activities gave important role on distinguishing the area and perimeter of circles.

Effects of antibody, drug and linker on the preclinical and clinical toxicities of antibody-drug conjugates

PubMed Central

Donaghy, Heather

2016-01-01

ABSTRACT Antibody-drug conjugates (ADCs) represent a new class of cancer therapeutics. Their design involves a tumor-specific antibody, a linker and a cytotoxic payload. They were designed to allow specific targeting of highly potent cytotoxic agents to tumor cells whilst sparing normal cells. Frequent toxicities that may be driven by any of the components of an ADC have been reported. There are currently more than 50 ADCs in active clinical development, and a further ∼20 that have been discontinued. For this review, the reported toxicities of ADCs were analysed, and the mechanisms for their effects are explored in detail. Methods to reduce toxicities, including dosing strategies and drug design, are discussed. The toxicities reported for active and discontinued drugs are important to drive the rational design and improve the therapeutic index of ADCs of the future. PMID:27045800

Jordanian Nurses' involvement in health policy: perceived benefits and barriers.

PubMed

AbuAlRub, R F; Foudeh, F N

2017-03-01

To examine (1) the level of involvement of Jordanian nurses in health policy development and (2) perceived benefits, barriers and impacts on health outcomes of involvement in health policy process. Lack of nurses' political involvement may result in self-serving policies by policymakers who are in power and passing policies that are less than optimum. A descriptive cross-sectional design was adopted in this study. A convenience sample of 231 nurses was recruited with a response rate of 77%. The instrument of Registered Nurses' Involvement in Health Policies was used in this study. The results revealed that participants were most frequently involved in the health policy activity 'voting for a candidate or a health policy proposal'. The mean scores for involvement of participants as nurses and as citizens were low. The most perceived frequent barrier to involvement in health policy was lack of time. The low rate of Jordanian nurses' involvement in health policy could be explained by the fact that most participants had family roles in addition to work roles, which might leave little time for health policy activities. Lack of mentoring for nurses by nursing leaders could also negatively affect their involvement in health policy development. Results of this study could be baseline information for Jordanian nurse leaders to enhance the level of nurses' involvement in health policy development. Such findings could also add knowledge to the existing literature about nurses' involvement in health policy. © 2016 International Council of Nurses.

Designing with Only Four People in Mind? - A Case Study of Using Personas to Redesign a Work-Integrated Learning Support System

NASA Astrophysics Data System (ADS)

Dotan, Amir; Maiden, Neil; Lichtner, Valentina; Germanovich, Lola

In this paper we describe and reflect on the use of personas to redesign the 3rd prototype of APOSDLE - a system to support informal learning and knowledge transfer in the workplace. Based on the results of a formative evaluation of the 2nd prototype we used personas to explore how users’ goals, behaviour and preferences could be communicated to project members during a two-day design workshop, in order to ensure useful and usable design solutions. We actively involved stakeholders representing the target market throughout the process as they helped to create, validate and interpret the four personas we used. By doing so we aimed to address methodological weaknesses and practical limitations of using personas, primarily those relating to the validity of the personas used and the way they are interpreted. We reflected on how effective the personas were by referring to data generated during the workshop and discussion transcripts. As reported by others, and as we have experienced ourselves, using personas can be quite challenging as rich narrative descriptions are expected to produce insight and design solutions. In light of this challenge, we contribute a case study illustrating how personas were implemented in a real world situation to engage project members with user information and drive the design process. We specifically discussed the strengths and weaknesses of actively involving stakeholders in creating and using personas.

The limits of intelligence in design

DOE Office of Scientific and Technical Information (OSTI.GOV)

Papamichael, K.; Protzen, J.P.

1993-05-01

A new, comprehensive design theory is presented, applicable to all design domains such as engineering and industrial design, architecture, city and regional planning, and, in general, any goal-oriented activity that involves decision making. The design process is analyzed into fundamental activities that are characterized with respect to the nature of knowledge requirements and the degree to which they can be specified and delegated to others, in general, and to computers in particular. The characterization of design problems as ``wicked,`` or ``ill-defined,`` design has been understood as a rational activity, that is ``thinking before acting.`` The new theory presented in thismore » paper suggests that design is ``thinking and feeling while acting,`` supporting the position that design is only partially rational. Intelligence, ``natural`` or ``artificial,`` is only one of two requirements for design, the other being emotions. Design decisions are only partially inferred, that is, they are not entirely the product of reasoning. Rather, design decisions are based on judgment that requires the notion of ``good`` and ``bad,`` which is attributed to feelings, rather than thoughts. The presentation of the design theory extends to the implications associated with the limits of intelligence in design, which, in turn, become constraints on the potential role of computers in design. Many of the current development efforts in computer-aided design violate these constraints, especially in the implementation of expert systems and multi-criterion evaluation models. These violations are identified and discussed in detail. Finally, specific areas for further research and development in computer-aided design are presented and discussed.« less

Brain Activity During the Encoding, Retention, and Retrieval of Stimulus Representations

PubMed Central

de Zubicaray, Greig I.; McMahon, Katie; Wilson, Stephen J.; Muthiah, Santhi

2001-01-01

Studies of delayed nonmatching-to-sample (DNMS) performance following lesions of the monkey cortex have revealed a critical circuit of brain regions involved in forming memories and retaining and retrieving stimulus representations. Using event-related functional magnetic resonance imaging (fMRI), we measured brain activity in 10 healthy human participants during performance of a trial-unique visual DNMS task using novel barcode stimuli. The event-related design enabled the identification of activity during the different phases of the task (encoding, retention, and retrieval). Several brain regions identified by monkey studies as being important for successful DNMS performance showed selective activity during the different phases, including the mediodorsal thalamic nucleus (encoding), ventrolateral prefrontal cortex (retention), and perirhinal cortex (retrieval). Regions showing sustained activity within trials included the ventromedial and dorsal prefrontal cortices and occipital cortex. The present study shows the utility of investigating performance on tasks derived from animal models to assist in the identification of brain regions involved in human recognition memory. PMID:11584070

Exercise prescription for the elderly: current recommendations.

PubMed

Mazzeo, R S; Tanaka, H

2001-01-01

The benefits for elderly individuals of regular participation in both cardiovascular and resistance-training programmes are great. Health benefits include a significant reduction in risk of coronary heart disease, diabetes mellitus and insulin resistance, hypertension and obesity as well as improvements in bone density, muscle mass, arterial compliance and energy metabolism. Additionally, increases in cardiovascular fitness (maximal oxygen consumption and endurance), muscle strength and overall functional capacity are forthcoming allowing elderly individuals to maintain their independence, increase levels of spontaneous physical activity and freely participate in activities associated with daily living. Taken together, these benefits associated with involvement in regular exercise can significantly improve the quality of life in elderly populations. It is noteworthy that the quality and quantity of exercise necessary to elicit important health benefits will differ from that needed to produce significant gains in fitness. This review describes the current recommendations for exercise prescriptions for the elderly for both cardiovascular and strength/resistance-training programmes. However, it must be noted that the benefits described are of little value if elderly individuals do not become involved in regular exercise regimens. Consequently, the major challenges facing healthcare professionals today concern: (i) the implementation of educational programmes designed to inform elderly individuals of the health and functional benefits associated with regular physical activity as well as how safe and effective such programmes can be; and (ii) design interventions that will both increase involvement in regular exercise as well as improve adherence and compliance to such programmes.

Consumer involvement in cancer research: example from a Cancer Network.

PubMed

Arain, Mubashir; Pyne, Sarah; Thornton, Nigel; Palmer, Susan; Sharma, Ricky A

2015-10-01

The involvement of consumers and the general public in improving cancer services is an important component of health services. However, consumer involvement in cancer research is relatively unexplored. The objective of this study was to explore different ways of involving consumers in cancer research in one regional network. Thames Valley Cancer Network Consumer Research Partnership (CRP) group was formed in 2009. The group consists of consumers and professionals to help in promoting consumer involvement in Cancer Research in the Thames Valley. This study evaluated the project of consumer involvement in cancer research in the Thames Valley from March 2010 to March 2011. We used different indices to judge the level of consumer involvement: number of projects involving consumers through the group, types of projects, level of involvement (ranged from consultation on research documents to collaborating in preparing grant applications) and the methods of involving consumers in cancer research. Fifteen projects were submitted to the CRP group during the 12-month period studied. Of these, eight projects were clinical trials, three were qualitative research projects, two were patients' surveys and two were non-randomized interventional studies. Seven projects requested consumer involvement on patient information sheets for clinical trials. Of these seven applications, three also requested consumers' help in designing research questionnaires and another three requested that consumers should be involved in their project management group. In addition, four projects involved consumers in the proposal development phase and another four projects asked for advice on how to increase trial recruitment, conduct patient interviews or help with grant applications. The creation of the CRP and this audit of its activity have documented consumer involvement in cancer research in the Thames Valley. We have clearly shown that consumers can be involved in designing and managing cancer research projects. © 2013 John Wiley & Sons Ltd.

Complement, a target for therapy in inflammatory and degenerative diseases.

PubMed

Morgan, B Paul; Harris, Claire L

2015-12-01

The complement system is a key innate immune defence against infection and an important driver of inflammation; however, these very properties can also cause harm. Inappropriate or uncontrolled activation of complement can cause local and/or systemic inflammation, tissue damage and disease. Complement provides numerous options for drug development as it is a proteolytic cascade that involves nine specific proteases, unique multimolecular activation and lytic complexes, an arsenal of natural inhibitors, and numerous receptors that bind to activation fragments. Drug design is facilitated by the increasingly detailed structural understanding of the molecules involved in the complement system. Only two anti-complement drugs are currently on the market, but many more are being developed for diseases that include infectious, inflammatory, degenerative, traumatic and neoplastic disorders. In this Review, we describe the history, current landscape and future directions for anti-complement therapies.

Toward a framework for computer-mediated collaborative design in medical informatics.

PubMed

Patel, V L; Kaufman, D R; Allen, V G; Shortliffe, E H; Cimino, J J; Greenes, R A

1999-09-01

The development and implementation of enabling tools and methods that provide ready access to knowledge and information are among the central goals of medical informatics. The need for multi-institutional collaboration in the development of such tools and methods is increasingly being recognized. Collaboration involves communication, which typically involves individuals who work together at the same location. With the evolution of electronic modalities for communication, we seek to understand the role that such technologies can play in supporting collaboration, especially when the participants are geographically separated. Using the InterMed Collaboratory as a subject of study, we have analyzed their activities as an exercise in computer- and network-mediated collaborative design. We report on the cognitive, sociocultural, and logistical issues encountered when scientists from diverse organizations and backgrounds use communications technologies while designing and implementing shared products. Results demonstrate that it is important to match carefully the content with the mode of communication, identifying, for example, suitable uses of E-mail, conference calls, and face-to-face meetings. The special role of leaders in guiding and facilitating the group activities can also be seen, regardless of the communication setting in which the interactions occur. Most important is the proper use of technology to support the evolution of a shared vision of group goals and methods, an element that is clearly necessary before successful collaborative designs can proceed.

The Workshop Program on Authentic Assessment for Science Teachers

NASA Astrophysics Data System (ADS)

Rustaman, N. Y.; Rusdiana, D.; Efendi, R.; Liliawati, W.

2017-02-01

A study on implementing authentic assessment program through workshop was conducted to investigate the improvement of the competence of science teachers in designing performance assessment in real life situation at school level context. A number of junior high school science teachers and students as participants were involved in this study. Data was collected through questionnaire, observation sheets, and pre-and post-test during 4 day workshop. This workshop had facilitated them direct experience with seventh grade junior high school students during try out. Science teachers worked in group of four and communicated each other by think-pair share in cooperative learning approach. Research findings show that generally the science teachers’ involvement and their competence in authentic assessment improved. Their knowledge about the nature of assessment in relation to the nature of science and its instruction was improved, but still have problem in integrating their design performance assessment to be implemented in their lesson plan. The 7th grade students enjoyed participating in the science activities, and performed well the scientific processes planned by group of science teachers. The response of science teachers towards the workshop was positive. They could design the task and rubrics for science activities, and revised them after the implementation towards the students. By participating in this workshop they have direct experience in designing and trying out their ability within their professional community in real situation towards their real students in junior high school.

Paying attention to emotion: an fMRI investigation of cognitive and emotional stroop tasks.

PubMed

Compton, Rebecca J; Banich, Marie T; Mohanty, Aprajita; Milham, Michael P; Herrington, John; Miller, Gregory A; Scalf, Paige E; Webb, Andrew; Heller, Wendy

2003-06-01

In this research, we investigated the degree to which brain systems involved in ignoring emotionally salient information differ from those involved in ignoring nonemotional information. The design allowed examination of regional brain activity, using fMRI during color-word and emotional Stroop tasks. Twelve participants indicated the color of words while ignoring word meaning in conditions in which neutral words were contrasted to emotionally negative, emotionally positive, and incongruent color words. Dorsolateral frontal lobe activity was increased by both negative and incongruent color words, indicating a common system for maintaining an attentional set in the presence of salient distractors. In posterior regions of the brain, activity depended on the nature of the information to be ignored. Ignoring color-incongruent words increased left parietal activity and decreased parahippocampal gyrus activity, whereas ignoring negative emotional words increased bilateral occipito-temporal activity and decreased amygdala activity. The results indicate that emotion and attention are intimately related via a network of regions that monitor for salient information, maintain attention on the task, suppress irrelevant information, and select appropriate responses.

From Grave Rubbings to Maximilian's Journey.

ERIC Educational Resources Information Center

Hoffman, Elizabeth; Young, Michael

A high school project growing out of efforts to involve students in a German-American tricentennial celebration and designed to make student-centered activities educationally meaningful to both social studies and German language students is described. The project had the following objectives: (1) to view, through an interdisciplinary approach, the…

Using Technology Effectively to Teach about Fractions

ERIC Educational Resources Information Center

Hensberry, Karina K. R.; Moore, Emily B.; Perkins, Katherine

2015-01-01

In this article, the authors describe classroom use of technology that successfully engaged fourth grade students (typically aged 9-10) in the United States in learning about fractions. The activities involved the use of an interactive simulation designed to support student learning of fractions, and whole-class discussion where students were…

A Consumer's Guide to the Federal Trade Commission.

ERIC Educational Resources Information Center

Williams, Elizabeth

This publication presents consumer information designed to encourage and facilitate active citizen involvement in Federal Trade Commission (FTC) proceedings. Nine chapters are included, covering (1) the FTC and its impact on consumers (discusses the authority of FTC, the Bureau of Competition, the Bureau of Consumer Protection, and lists FTC…

Sleep Does Not Enhance Motor Sequence Learning

ERIC Educational Resources Information Center

Rickard, Timothy C.; Cai, Denise J.; Rieth, Cory A.; Jones, Jason; Ard, M. Colin

2008-01-01

Improvements in motor sequence performance have been observed after a delay involving sleep. This finding has been taken as evidence for an active sleep consolidation process that enhances subsequent performance. In a review of this literature, however, the authors observed 4 aspects of data analyses and experimental design that could lead to…

76 FR 77852 - Agency Information Collection Activities: Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-14

... $109,000; this cost includes: research staff involved in survey design, piloting, implementation... Evaluation.'' The proposed project includes a survey of teachers' use of the National Science, Technology..., services) for STEM education and research. The teacher survey is part of a Phase 3 evaluation that builds...

Pedagogical Concerns in Doctoral Supervision: A Challenge for Pedagogy

ERIC Educational Resources Information Center

Zeegers, Margaret; Barron, Deirdre

2012-01-01

Purpose: The purpose of this paper is to focus on pedagogy as a crucial element in postgraduate research undertakings, implying active involvement of both student and supervisor in process of teaching and learning. Design/methodology/approach: Drawing on Australian higher degree research supervision practice to illustrate their argument, the…

Improving the Perceptual Performance of Learning Disabled Second Graders through Computer Assisted Instruction.

ERIC Educational Resources Information Center

Burke, James P.

The practicum designed a perceptual activities program for learning disabled second graders using computer-assisted instruction. The program develops skills involving visual motor coordination, figure-ground differentiation, form constancy, position in space, and spatial relationships. Five behavioral objectives for each developmental area were…

Enabling Critical Reflection on Research Supervisory Practice

ERIC Educational Resources Information Center

Pearson, Margot; Kayrooz, Carole

2004-01-01

This paper describes the development of an instrument--The Reflective Supervisor Questionnaire (RSQ). The RSQ maps the domain of research supervisory practice as a facilitative process involving educational tasks and activities. It is designed to assist research supervisors explore, by means of self-reflection and reflection on feedback from…

The Winter Olympics--On Ice.

ERIC Educational Resources Information Center

Hoover, Barbara G.

1998-01-01

Describes several science activities designed around the upcoming Winter Olympics ice skating events which demonstrate the scientific principles behind the sport. Students learn that increasing the pressure on ice will lead to the ice melting, the principle involved in the spinning swing, and the technology of skates and skating outfits. (PVD)

Further Research on an Undergraduate Measure of Professional Development Engagement

ERIC Educational Resources Information Center

Blau, Gary; Pred, Robert; Andersson, Lynne; Lopez, Andrea B.

2015-01-01

Professional Development Engagement (PDE) refers to the level of undergraduate engagement in professional development. Professional Development (PD) involves activities designed to help students prepare for a successful college-to-work transition. This study tested a new 12-item measure of PDE for a complete-data sample of 246 undergraduate…

Developing Course Materials for Technology-Mediated Chinese Language Learning

ERIC Educational Resources Information Center

Kubler, Cornelius C.

2018-01-01

This article discusses principles involved in developing course materials for technology-mediated Chinese language learning, with examples from a new course designed to take into account the needs of distance and independent learners. Which learning environment is most efficient for a given learning activity needs to be carefully considered. It…

The New Youth Entrepreneur: Money To Get Started. Module 5.

ERIC Educational Resources Information Center

Kourilsky, Marilyn; And Others

The New Youth Entrepreneur curriculum is a series of 12 youth-oriented educational modules containing instructional materials, learning activities, and checkup exercises designed to teach students key elements of entrepreneurship. This document is the fifth module, and introduces students to the financial issues involved in starting a business,…

Facilitating College Readiness through Campus Life Experiences

ERIC Educational Resources Information Center

Schaefer, Mary Beth

2014-01-01

In a program called "College Immersion," middle grades students spend up to one week on a local college campus, attending specially designed college classes and experiencing collegiate activities. This research study reports on findings related to two different college-middle school partnerships involved in a College Immersion program.…

Elections: Secondary Teaching Activities in the Participation Series.

ERIC Educational Resources Information Center

Schultz, John; Taft-Morales, Hugh

One of a series of teacher-developed curriculum guides designed to encourage student participation and involvement in important social issues, this secondary level guide helps 7th through 12th grade English and social studies educators teach about the election process. An introductory section suggests practical considerations, means of enlisting…

PEAS AND PARTICLES, TEACHER'S GUIDE.

ERIC Educational Resources Information Center

1966

THIS TEACHER'S GUIDE IS DESIGNED FOR USE WITH AN ELEMENTARY SCIENCE STUDY UNIT ON "PEAS AND PARTICLES" WHICH DEALS WITH LARGE NUMBERS AND ESTIMATIONS. ITS PURPOSE IS TO GIVE ELEMENTARY SCHOOL CHILDREN AN UNDERSTANDING OF WHAT LARGE NUMBERS MEAN THROUGH INFORMAL ACTIVITIES INVOLVING FAMILIAR OBJECTS. THE MATERIAL HAS BEEN FOUND SUITABLE…

TEACHER'S GUIDE FOR MICROGARDENING.

ERIC Educational Resources Information Center

CHANDLER, MARION N.

THIS TEACHING GUIDE IS DESIGNED FOR USE WITH AN ELEMENTARY SCIENCE STUDY UNIT "MICROGARDENING" IN WHICH SIMPLER AND LOWER FORMS OF PLANT LIFE ARE STUDIED THROUGH STUDENT ACTIVITIES INVOLVING MOLDS. THE MATERIALS HAVE BEEN CLASSROOM TESTED AND ARE SUGGESTED FOR MIDDLE AND UPPER ELEMENTARY GRADES. THE WORK HAS BEEN ORGANIZED IN FIVE AREAS…

My First Million: A Fantasy for the Future.

ERIC Educational Resources Information Center

Trede, Mildred

1990-01-01

The paper presents activities for improving students' literacy, oral communication, and thinking skills. Students brainstorm ideas for improving consumer products, think of ideas for starting a business, design an advertisement, estimate costs involved, create a demand for the product or service, and write a research paper on relieving stress.…

Training Teachers to be Professional Development Leaders.

ERIC Educational Resources Information Center

Leslie, Jessica B.

1982-01-01

A Teacher Corps project conducted by the Edgewood Independent School District and Trinity University (San Antonio, Texas) is described. A classroom teacher at each participating school is trained to lead professional development activities at his or her school. Teacher involvement in designing professional development at each school is emphasized.…

Serving Exceptional Children. A Report to the Idaho Legislature, January 2004.

ERIC Educational Resources Information Center

Idaho State Department of Education, 2004

2004-01-01

This report provides information on 2002-2003 school year activities involving exceptional students. The term "exceptional students" refers to individuals with disabilities or gifts and talents who have unique needs that require specially designed instruction, administrative accommodations, or curriculum modifications in order to receive an…

Articulating the Resources for Business Process Analysis and Design

ERIC Educational Resources Information Center

Jin, Yulong

2012-01-01

Effective process analysis and modeling are important phases of the business process management lifecycle. When many activities and multiple resources are involved, it is very difficult to build a correct business process specification. This dissertation provides a resource perspective of business processes. It aims at a better process analysis…

Gamified Vocabulary: Online Resources and Enriched Language Learning

ERIC Educational Resources Information Center

Abrams, Sandra Schamroth; Walsh, Sara

2014-01-01

This article explores the ways "gamification" can play a role in adolescents' development of vocabulary. Gamification involves the application of game-design thinking and play elements to non-game activities, such as routine homework or classroom lessons. Drawing upon data from in-school and after-school settings, the authors…

A Directed Research Project Investigating Aggressive Behavior in Paradise Fish.

ERIC Educational Resources Information Center

Darling, Ruth A.

2003-01-01

Presents a laboratory experiment that examines the aggressive behavior of male paradise fish. Students design the experiment, collect data, and analyze and interpret the results. This activity is appropriate for biology, ecology, and animal behavior classes and allows students to be involved in the entire scientific process. (Author/NB)

Progression of Cohort Learning Style during an Intensive Education Program

ERIC Educational Resources Information Center

Compton, David A.; Compton, Cynthia M.

2017-01-01

The authors describe an intensive graduate program involving compressed classroom preparation followed by a period of experiential activities designed to reinforce and enhance the knowledge base. Beginning with a brief review of the andragogical issues, they describe methods undertaken to track learning styles via the Kolb Learning Styles…

Dancing Hearts: Creative Arts with Books Kids Love.

ERIC Educational Resources Information Center

Brady, Martha

This book focuses on the integration of children's literature and creative arts. Each chapter begins with a "Background" section designed to familiarize the reader with the children's book that is showcased. This is followed by the "Hook" activity, a starter experience that involves the entire class in a doing-and-listening…

Globally Networked Collaborative Learning in Industrial Design

ERIC Educational Resources Information Center

Bohemia, Erik; Ghassan, Aysar

2012-01-01

This article explores project-based cross-cultural and cross-institutional learning. Using Web 2.0 technologies, this project involved more than 240 students and eighteen academic staff from seven international universities. The focus of this article relates to a project-based learning activity named "The Gift". At each institution the…

An Open-Ended Investigative Microbial Ecology Laboratory for Introductory Biology

ERIC Educational Resources Information Center

Jones-Held, Susan; Paoletti, Robert; Glick, David; Held, Michael E.

2010-01-01

In this article we describe a multi-week investigative laboratory in microbial ecology/diversity and nitrogen cycling that we have used in our introductory biology course. This module encourages active student involvement in experimental design, using the scientific literature and quantitative analysis of large data sets. Students analyze soil…

The Contribution of Visualization to Learning Computer Architecture

ERIC Educational Resources Information Center

Yehezkel, Cecile; Ben-Ari, Mordechai; Dreyfus, Tommy

2007-01-01

This paper describes a visualization environment and associated learning activities designed to improve learning of computer architecture. The environment, EasyCPU, displays a model of the components of a computer and the dynamic processes involved in program execution. We present the results of a research program that analysed the contribution of…

Introduction to Media.

ERIC Educational Resources Information Center

Riler, Robert

Designed for senior high school students, this one semester course focuses on four aspects of modern media: television, film, radio, and advertising. Each topic is worked into a weekly lesson plan format that stresses the active involvement of students in the learning process. The course outline contains lists of objectives and media materials…

Place-Based Education: A Transformative Activist Stance

ERIC Educational Resources Information Center

Coughlin, Christine A.; Kirch, Susan A.

2010-01-01

The ethnography presented by van Eijck and Roth focuses on the activities of people involved in a government funded internship program in conservation and restoration, which was offered by a "multidisciplinary research center" through a local First Nation adult education center. The internship was designed, in partnership with a local non-profit…

Drama Techniques in Language Learning.

ERIC Educational Resources Information Center

Maley, Alan; Duff, Alan

The drama activities in this teaching guide are designed to develop second language learning skills by constructing situations that require the student to concentrate on the meaning and emotional content of language rather than on its structure. In an attempt to involve the whole personality of the learner in the acquisition of language, the…

Tackling Production Techniques: Vacations via Kodak's Visualmaker.

ERIC Educational Resources Information Center

Martin, Ron

1986-01-01

Describes a library media production activity in which each student uses a Kodak Ektagraphic Visualmaker to produce a color slide illustrating his/her winter vacation. The project is designed to be low-budget and to involve uncomplicated equipment. Included are explanations of performance objectives, materials, procedures, and evaluation. (EM)

Oral History as a Motivating Factor among Adult Learners.

ERIC Educational Resources Information Center

Lawrence, Janet H.; Lehman, Esther

An exploratory study was designed to assess (1) whether a class created around older adults' personal recollections would motivate the class's involvement in adult education activities, (2) the oral history preparation process's impact on younger interviewers and older respondents, and (3) the instructional approach's strengths and weaknesses. The…

A Conceptual Framework for Examining Knowledge Management in Higher Education Contexts

ERIC Educational Resources Information Center

Lee, Hae-Young; Roth, Gene L.

2009-01-01

Knowledge management is an on-going process that involves varied activities: diagnosis, design, and implementation of knowledge creation, knowledge transfer, and knowledge sharing. The primary goal of knowledge management, like other management theories or models, is to identify and leverage organizational and individual knowledge for the…

Electronic Performance Monitoring: An Organizational Justice and Concertive Control Perspective.

ERIC Educational Resources Information Center

Alder, G. Stoney; Tompkins, Phillip K.

1997-01-01

Applies theories of organizational justice/concertive control to account for contradictions inherent in electronic monitoring of workers by organizations. Argues that results are usually positive when workers are involved in the design and implementation of monitoring systems, and monitoring is restricted to performance-related activities with…

Drug Education Curriculum: Junior High. Health Education: Substance Abuse Prevention.

ERIC Educational Resources Information Center

New York State Education Dept., Albany. Bureau of Drug Education.

This curriculum guide, one of nine sequential manuals for elementary and secondary teachers and administrators, is designed to prevent drug misuse and abuse through activities for developing students' cognitive and affective skills. The materials emphasize the involvement of parents and community members and resources in implementing drug abuse…

Active Games: An Approach to Teaching Mathematical Skills to the Educable Mentally Retarded

ERIC Educational Resources Information Center

Taylor, George R.; Watkins, Susan T.

1974-01-01

Several games involving both motor behavior and practice with mathematical skills are described. These include adaptations of musical chairs (subtraction), call ball (multiplication), and ring toss (linear measurement); other games are designed to provide practice on identifying numerals, telling time, using money, and naming fractions. (SD)

Do University Students, Alumni, Educators and Employers Link Assessment and Graduate Employability?

ERIC Educational Resources Information Center

Kinash, Shelley; McGillivray, Laura; Crane, Linda

2018-01-01

Within higher education literature, "assessment" and "graduate employability" are linked and co-presented, in that quality student assessment is purported to enhance employability. This research was designed to query the extent to which these same conceptual links are perceived by those actively involved in higher education.…

Design and Development of a Smart Storytelling Toy

ERIC Educational Resources Information Center

Kara, Nuri; Aydin, Cansu Cigdem; Cagiltay, Kursat

2014-01-01

Because computers generally make children passive listeners, new technological devices need to support children's storytelling activities. This article introduces the StoryTech, a smart toy that includes a virtual space comprised of computer-based graphics and characters as well as a real space that involves stuffed animals, background cards…

Strategies To Enhance Memory Based on Brain-Research.

ERIC Educational Resources Information Center

Banikowski, Alison K.; Mehring, Teresa A.

1999-01-01

This article reviews the literature on three aspects of memory: (1) an information processing model of memory (including the sensory register, attention, short-term memory, and long-term memory); (2) instructional strategies designed to enhance memory (which stress gaining students' attention and active involvement); and (3) reasons why…

Designing Algebraic Tasks for 7-Year-Old Students--A Pilot Project Inspired by Davydov's "Learning Activity" Concept

ERIC Educational Resources Information Center

Eriksson, Inger; Jansson, Anders

2017-01-01

The issue of this article is to identify and discuss what conditions may be necessary to build into tasks to make it likely for students to be involved in an algebraic Learning Activity inspired by Davydov. Data from a pilot study was used in which a group of students (N = 28) in grade 1 (7-year-olds) were invited to participate in discussions and…

Think Locally, Act Globally! Linking Local and Global Communities through Democracy and Environment. Hands-On! Developing Active Learning Modules on the Human Dimensions of Global Change.

ERIC Educational Resources Information Center

Dowler, Lorraine

Designed so that it can be adapted to a wide range of student abilities and institutional settings, this learning module on the human dimensions of global change seeks to: actively engage students in problem solving, challenge them to think critically, invite them to participate in the process of scientific inquiry, and involve them in cooperative…

ECUT: Energy Conversion and Utilization Technologies program. Biocatalysis project

NASA Technical Reports Server (NTRS)

1990-01-01

The Biocatalysis Project is a mission-oriented, applied research and exploratory development activity directed toward resolution of the major generic technical barriers that impede the development of biologically catalyzed commercial chemical production. The approach toward achieving project objectives involves an integrated participation of Universities, Industrial Companies and Government Research Laboratories. The Project's technical activities were organized into three work elements: molecular modeling and applied genetics; bioprocess engineering; and bioprocess design and assessment.

Energy Based Topology Optimization of Morphing Wings a Multidisciplinary Global/Local Design Approach

DTIC Science & Technology

2006-12-01

subsystem that drives the active materials to achieve the desired shape changes. As opposed to fixed wing structures in which the aerodynamic and...structures and aerodynamics occur in conjunction with the active material and electronic subsystem interactions that involve transfer of energy from a source...which the aerodynamic and structure integration for the entire wing is the most important interaction mechanism, in the case of a morphing wing

Bringing Nature to Schools to Promote Children's Physical Activity.

PubMed

Sharma-Brymer, Vinathe; Bland, Derek

2016-07-01

Physical activity (PA) is essential for human health and wellbeing across all age, socioeconomic, and ethnic groups. Engagement with the natural world is a new defining criterion for enhancing the benefits of PA, particularly for children and young people. Interacting with nature benefits children's social and emotional wellbeing, develops resilience, and reduces the risk of obesity and type 2 diabetes mellitus across all population groups. Governments around the world are now recognizing the importance of children spending more active time outdoors. However, children's outdoor activities, free play, and nature-related exploration are often structured and supervised by adults due to safety concerns and risks. In this context, schools become more accessible and safe options for children to engage in PA outdoors with the presence of nature features. Research on school designs involving young children has revealed that children prefer nature-related features in school environments. Affordances in nature may increase children's interest in physically active behaviors. Given that present school campuses are designed for operational efficiency and economic reasons, there is a need to re-design schools responding to the positive role of nature on human health. If schools were re-designed to incorporate diverse natural features, children's PA and consequent health and wellbeing would likely improve markedly.

Rotating rake design for unique measurement of fan-generated spinning acoustic modes

NASA Technical Reports Server (NTRS)

Konno, Kevin E.; Hausmann, Clifford R.

1993-01-01

In light of the current emphasis on noise reduction in subsonic aircraft design, NASA has been actively studying the source of and propagation of noise generated by subsonic fan engines. NASA/LeRC has developed and tested a unique method of accurately measuring these spinning acoustic modes generated by an experimental fan. This mode measuring method is based on the use of a rotating microphone rake. Testing was conducted in the 9 x 15 Low-speed Wind Tunnel. The rotating rake was tested with the Advanced Ducted Propeller (ADP) model. This memorandum discusses the design and performance of the motor/drive system for the fan-synchronized rotating acoustic rake. This novel motor/drive design approach is now being adapted for additional acoustic mode studies in new test rigs as baseline data for the future design of active noise control for subsonic fan engines. Included in this memorandum are the research requirements, motor/drive specifications, test performance results, and a description of the controls and software involved.

The role of right and left parietal lobes in the conceptual processing of numbers.

PubMed

Cappelletti, Marinella; Lee, Hwee Ling; Freeman, Elliot D; Price, Cathy J

2010-02-01

Neuropsychological and functional imaging studies have associated the conceptual processing of numbers with bilateral parietal regions (including intraparietal sulcus). However, the processes driving these effects remain unclear because both left and right posterior parietal regions are activated by many other conceptual, perceptual, attention, and response-selection processes. To dissociate parietal activation that is number-selective from parietal activation related to other stimulus or response-selection processes, we used fMRI to compare numbers and object names during exactly the same conceptual and perceptual tasks while factoring out activations correlating with response times. We found that right parietal activation was higher for conceptual decisions on numbers relative to the same tasks on object names, even when response time effects were fully factored out. In contrast, left parietal activation for numbers was equally involved in conceptual processing of object names. We suggest that left parietal activation for numbers reflects a range of processes, including the retrieval of learnt facts that are also involved in conceptual decisions on object names. In contrast, number selectivity in right parietal cortex reflects processes that are more involved in conceptual decisions on numbers than object names. Our results generate a new set of hypotheses that have implications for the design of future behavioral and functional imaging studies of patients with left and right parietal damage.

Parental Involvement in a School-Based Child Physical Activity and Nutrition Program in Southeastern United States: A Qualitative Analysis of Parenting Capacities.

PubMed

Ickes, Scott; Mahoney, Emily; Roberts, Alison; Dolan, Carrie

2016-03-01

Parent involvement varies widely in school-based programs designed to promote physical activity and healthy nutrition, yet the underlying factors that may limit parent's participation and support of learned behaviors at home are not well understood. We conducted a qualitative study that consisted of one focus group (n = 5) and 52 in-depth interviews among parents whose children participated in a school-based physical activity and nutrition (PAN) promotion program in Williamsburg, Virginia, United States. We sought to identify factors that enabled or constrained parent's support of and involvement in children's programs and to understand the underlying factors that contribute to family success in making dietary and physical activity changes at home. Parents identified their physical and mental health, self-confidence, time, and decision making as underlying "capacities" in the family health pattern. When strengthened, these capacities encourage healthful family behavior and support of school-based PAN programs. Families that succeeded in adopting lessons learned from school-based PAN programs identified four primary strategies for success: shared goals, meal planning, modeling of good behaviors, and collective activities. Interventions that aim to improve child nutrition and physical activity and the broader family health environment should consider underlying capacities of parents and the importance of joint goals and activities. © 2016 Society for Public Health Education.

General approach and scope. [rotor blade design optimization

NASA Technical Reports Server (NTRS)

Adelman, Howard M.; Mantay, Wayne R.

1989-01-01

This paper describes a joint activity involving NASA and Army researchers at the NASA Langley Research Center to develop optimization procedures aimed at improving the rotor blade design process by integrating appropriate disciplines and accounting for all of the important interactions among the disciplines. The disciplines involved include rotor aerodynamics, rotor dynamics, rotor structures, airframe dynamics, and acoustics. The work is focused on combining these five key disciplines in an optimization procedure capable of designing a rotor system to satisfy multidisciplinary design requirements. Fundamental to the plan is a three-phased approach. In phase 1, the disciplines of blade dynamics, blade aerodynamics, and blade structure will be closely coupled, while acoustics and airframe dynamics will be decoupled and be accounted for as effective constraints on the design for the first three disciplines. In phase 2, acoustics is to be integrated with the first three disciplines. Finally, in phase 3, airframe dynamics will be fully integrated with the other four disciplines. This paper deals with details of the phase 1 approach and includes details of the optimization formulation, design variables, constraints, and objective function, as well as details of discipline interactions, analysis methods, and methods for validating the procedure.

Angiotensin-converting enzyme inhibitors delay the occurrence of renal involvement and are associated with a decreased risk of disease activity in patients with systemic lupus erythematosus--results from LUMINA (LIX): a multiethnic US cohort.

PubMed

Durán-Barragán, S; McGwin, G; Vilá, L M; Reveille, J D; Alarcón, G S

2008-07-01

To examine if angiotensin-converting enzyme (ACE) inhibitor use delays the occurrence of renal involvement and decreases the risk of disease activity in SLE patients. SLE patients (Hispanics, African Americans and Caucasians) from the lupus in minorities: nature vs nurture (LUMINA) cohort were studied. Renal involvement was defined as ACR criterion and/or biopsy-proven lupus nephritis. Time-to-renal involvement was examined by univariable and multivariable Cox proportional hazards regression analyses. Disease activity was examined with a case-crossover design and a conditional logistic regression model; in the case intervals, a decrease in the SLAM-R score >or=4 points occurred but not in the control intervals. Eighty of 378 patients (21%) were ACE inhibitor users; 298 (79%) were not. The probability of renal involvement free-survival at 10 yrs was 88.1% for users and 75.4% for non-users (P = 0.0099, log rank test). Users developed persistent proteinuria and/or biopsy-proven lupus nephritis (7.1%) less frequently than non-users (22.9%), P = 0.016. By multivariable Cox proportional hazards regression analyses, ACE inhibitors use [hazard ratio (HR) 0.27; 95% CI 0.09, 0.78] was associated with a longer time-to-renal involvement occurrence whereas African American ethnicity (HR 3.31; 95% CI 1.44, 7.61) was with a shorter time. ACE inhibitor use (54/288 case and 254/1148 control intervals) was also associated with a decreased risk of disease activity (HR 0.56; 95% CI 0.34, 0.94). ACE inhibitor use delays the development of renal involvement and associates with a decreased risk of disease activity in SLE; corroboration of these findings in other lupus cohorts is desirable before practice recommendations are formulated.

Interface Stability Influences Torso Muscle Recruitment and Spinal Load During Pushing Tasks

PubMed Central

LEE, P. J.; GRANATA, K. P.

2006-01-01

Handle or interface design can influence torso muscle recruitment and spinal load during pushing tasks. The objective of the study was to provide insight into the role of interface stability with regard to torso muscle recruitment and biomechanical loads on the spine. Fourteen subjects generated voluntary isometric trunk flexion force against a rigid interface and similar flexion exertions against an unstable interface, which simulated handle design in a cart pushing task. Normalized electromyographic (EMG) activity in the rectus abdominus, external oblique and internal oblique muscles increased with exertion effort. When using the unstable interface, EMG activity in the internal and external oblique muscle groups was greater than when using the rigid interface. Results agreed with trends from a biomechanical model implemented to predict the muscle activation necessary to generate isometric pushing forces and maintain spinal stability when using the two different interface designs. The co-contraction contributed to increased spinal load when using the unstable interface. It was concluded that handle or interface design and stability may influence spinal load and associated risk of musculoskeletal injury during manual materials tasks that involve pushing exertions. PMID:16540437

Optimization of the in silico designed Kemp eliminase KE70 by computational design and directed evolution

PubMed Central

Khersonsky, Olga; Röthlisberger, Daniela; Wollacott, Andrew M.; Murphy, Paul; Dym, Orly; Albeck, Shira; Kiss, Gert; Houk, K. N.; Baker, David; Tawfik, Dan S.

2013-01-01

Although de novo computational enzyme design has been shown to be feasible, the field is still in its infancy: the kinetic parameters of designed enzymes are still orders of magnitude lower than those of naturally occurring ones. Nonetheless, designed enzymes can be improved by directed evolution, as recently exemplified for the designed Kemp eliminase KE07. Random mutagenesis and screening resulted in variants with >200-fold higher catalytic efficiency, and provided insights about features missing in the designed enzyme. Here we describe the optimization of KE70, another designed Kemp eliminase. Amino acid substitutions predicted to improve catalysis in design calculations involving extensive backbone sampling were individually tested. Those proven beneficial were combinatorially incorporated into the originally designed KE70 along with random mutations, and the resulting libraries were screened for improved eliminase activity. Nine rounds of mutation and selection resulted in >400-fold improvement in the catalytic efficiency of the original KE70 design, reflected in both higher kcat and lower KM values, with the best variants exhibiting kcat/KM values of >5x104 s−1M−1. The optimized KE70 variants were characterized structurally and biochemically providing insights into the origins of the improvements in catalysis. Three primary contributions were identified: first, the reshaping of the active site cavity to achieve tighter substrate binding; second, the fine-tuning of the electrostatics around the catalytic His-Asp dyad; and third, stabilization of the active-site dyad in a conformation optimal for catalysis. PMID:21277311

The Dutch heart health community intervention 'Hartslag Limburg': results of an effect study at organizational level.

PubMed

Ronda, G; Van Assema, P; Ruland, E; Steenbakkers, M; Van Ree, J; Brug, J

2005-05-01

'Hartslag Limburg', a cardiovascular diseases (CVD) prevention programme, integrates a community strategy and a high-risk strategy to reduce CVD risk behaviours. This article presents the results of the effect evaluation study of the community intervention at the organizational level. Organizational changes were an intermediate goal of the Hartslag Limburg community intervention, as these are assumed to be a prerequisite for changes at the individual level. A baseline-post-test control group design was used. The baseline measurement was conducted in 1998 and the post-test measurement in 2001. At baseline, 700 organizations were selected in the Maastricht region, and 577 in a control region. All organizations that were potentially significant agents in health-promoting activities were included. Data on organizational involvement in health-promoting activities were gathered by means of structured questionnaires, and sent to organization representatives by mail. The overall post-test percentage of organizations involved in at least one activity relating to physical activity was higher in the Maastricht region than in the control region. Furthermore, the number of activities per organization involved in activities relating to healthy eating, smoking behaviour or physical activity was higher in the Maastricht region than in the control region at post-test. This study provided valuable information about organizational involvement in health-promoting activities, as well as important information to consider in future research in this area. Due to the limitations of the study, the importance of measuring change at different social levels in community-based programmes, and the scarcity of effect studies of community interventions at the organizational level, further research on this subject is warranted.

New exponential synchronization criteria for time-varying delayed neural networks with discontinuous activations.

PubMed

Cai, Zuowei; Huang, Lihong; Zhang, Lingling

2015-05-01

This paper investigates the problem of exponential synchronization of time-varying delayed neural networks with discontinuous neuron activations. Under the extended Filippov differential inclusion framework, by designing discontinuous state-feedback controller and using some analytic techniques, new testable algebraic criteria are obtained to realize two different kinds of global exponential synchronization of the drive-response system. Moreover, we give the estimated rate of exponential synchronization which depends on the delays and system parameters. The obtained results extend some previous works on synchronization of delayed neural networks not only with continuous activations but also with discontinuous activations. Finally, numerical examples are provided to show the correctness of our analysis via computer simulations. Our method and theoretical results have a leading significance in the design of synchronized neural network circuits involving discontinuous factors and time-varying delays. Copyright © 2015 Elsevier Ltd. All rights reserved.

Active member vibration control experiment in a KC-135 reduced gravity environment

NASA Technical Reports Server (NTRS)

Lawrence, C. R.; Lurie, B. J.; Chen, G.-S.; Swanson, A. D.

1991-01-01

An active member vibration control experiment in a KC-135 reduced gravity environment was carried out by the Air Force Flight Dynamics Laboratory and the Jet Propulsion Laboratory. Two active members, consisting of piezoelectric actuators, displacement sensors, and load cells, were incorporated into a 12-meter, 104 kg box-type test structure. The active member control design involved the use of bridge (compound) feedback concept, in which the collocated force and velocity signals are feedback locally. An impact-type test was designed to accommodate the extremely short duration of the reduced gravity testing window in each parabolic flight. The moving block analysis technique was used to estimate the modal frequencies and dampings from the free-decay responses. A broadband damping performance was demonstrated up to the ninth mode of 40 Hz. The best damping performance achieved in the flight test was about 5 percent in the fourth mode of the test structure.

Biochemical mechanisms of cisplatin cytotoxicity.

PubMed

Cepeda, Victoria; Fuertes, Miguel A; Castilla, Josefina; Alonso, Carlos; Quevedo, Celia; Pérez, Jose M

2007-01-01

Since the discovery by Rosenberg and collaborators of the antitumor activity of cisplatin 35 years ago, three platinum antitumor drugs (cisplatin, carboplatin and oxaliplatin) have enjoyed a huge clinical and commercial hit. Ever since the initial discovery of the anticancer activity of cisplatin, major efforts have been devoted to elucidate the biochemical mechanisms of antitumor activity of cisplatin in order to be able to rationally design novel platinum based drugs with superior pharmacological profiles. In this report we attempt to provide a current picture of the known facts pertaining to the mechanism of action of the drug, including those involved in drug uptake, DNA damage signals transduction, and cell death through apoptosis or necrosis. A deep knowledge of the biochemical mechanisms, which are triggered in the tumor cell in response to cisplatin injury not only may lead to the design of more efficient platinum antitumor drugs but also may provide new therapeutic strategies based on the biochemical modulation of cisplatin activity.

An RNAi-mediated screen identifies novel targets for next-generation antiepileptic drugs based on increased expression of the homeostatic regulator pumilio.

PubMed

Lin, Wei-Hsiang; He, Miaomiao; Fan, Yuen Ngan; Baines, Richard A

2018-05-02

Despite availability of a diverse range of anti-epileptic drugs (AEDs), only about two-thirds of epilepsy patients respond well to drug treatment. Thus, novel targets are required to catalyse the design of next-generation AEDs. Manipulation of neuron firing-rate homoeostasis, through enhancing Pumilio (Pum) activity, has been shown to be potently anticonvulsant in Drosophila. In this study, we performed a genome-wide RNAi screen in S2R + cells, using a luciferase-based dPum activity reporter and identified 1166 genes involved in dPum regulation. Of these genes, we focused on 699 genes that, on knock-down, potentiate dPum activity/expression. Of this subgroup, 101 genes are activity-dependent based on comparison with genes previously identified as activity-dependent by RNA-sequencing. Functional cluster analysis shows these genes are enriched in pathways involved in DNA damage, regulation of cell cycle and proteasomal protein catabolism. To test for anticonvulsant activity, we utilised an RNA-interference approach in vivo. RNAi-mediated knockdown showed that 57/101 genes (61%) are sufficient to significantly reduce seizure duration in the characterized seizure mutant, para bss . We further show that chemical inhibitors of protein products of some of the genes targeted are similarly anticonvulsant. Finally, to establish whether the anticonvulsant activity of identified compounds results from increased dpum transcription, we performed a luciferase-based assay to monitor dpum promoter activity. Third instar larvae exposed to sodium fluoride, gemcitabine, metformin, bestatin, WP1066 or valproic acid all showed increased dpum promoter activity. Thus, this study validates Pum as a favourable target for AED design and, moreover, identifies a number of lead compounds capable of increasing the expression of this homeostatic regulator.

Breaking the addictive cycle of the system: improving US criminal justice practices to address substance use disorders.

PubMed

Kopak, Albert M

2015-01-01

Recent political commentary in the USA has suggested that there is great potential for current criminal justice practices designed for drug-involved offenders to be significantly overhauled in the near future. It is imperative to plan for these changes by assessing how well current programs serve drug-involved criminal justice populations. The paper aims to discuss these issues. This critical assessment begins with an overview of the most recent research on the prevalence and impact that substance use disorders have within the criminal justice system. Although the evidence demonstrates that relying on incarceration as a crime control method for drug-involved offenders has many shortcomings, there are innovative new programs being adopted across the country. Two of these promising programs are discussed, as well as the potential results that could be realized from integrating medication assisted treatment into appropriate criminal justice programs designed for drug-involved offenders. Incarceration is a failed practice for attending to the underlying reasons why many drug-involved offenders become involved in criminal activities. There are encouraging new programs emerging in different parts of the USA, but the inclusion of supplemental treatment options could further promote positive outcomes. The impending expansion of criminal justice programs for drug-involved offenders must consider how innovative new programs can be fused with supplemental treatment options to achieve the best results.

Bio-mimicking galactose oxidase and hemocyanin, two dioxygen-processing copper proteins.

PubMed

Gamez, Patrick; Koval, Iryna A; Reedijk, Jan

2004-12-21

The modelling of the active sites of metalloproteins is one of the most challenging tasks in bio-inorganic chemistry. Copper proteins form part of this stimulating field of research as copper enzymes are mainly involved in oxidation bio-reactions. Thus, the understanding of the structure-function relationship of their active sites will allow the design of effective and environmental friendly oxidation catalysts. This perspective illustrates some outstanding structural and functional synthetic models of the active site of copper proteins, with special attention given to models of galactose oxidase and hemocyanin.

Application of active controls technology to aircraft bide smoothing systems

NASA Technical Reports Server (NTRS)

Lapins, M.; Jacobson, I. D.

1975-01-01

A critical review of past efforts in the design and testing of ride smoothing and gust alleviation systems is presented. Design trade offs involving sensor types, choice of feedback loops, human comfort, and aircraft handling-qualities criteria are discussed. Synthesis of a system designed to employ direct-lift and side-force producing surfaces is reported. Two STOL aircraft and an executive transport are considered. Theoretically predicted system performance is compared with hybrid simulation and flight test data. Pilot opinion rating, pilot workload, and passenger comfort rating data for the basic and augmented aircraft are included.

Application of Active Controls Technology to Aircraft Ride Smoothing Systems

NASA Technical Reports Server (NTRS)

Lapins, Maris; Jacobson, Ira D.

1975-01-01

A critical review of past efforts in the design and testing of ride smoothing and gust alleviation systems is presented. Design trade-offs involving sensor types, choice of feedback loops, human comfort and aircraft handling-qualities criteria are discussed. Synthesis of a system designed to employ direct-lift and side-force producing surfaces is reported. Two STOL-class aircraft and an executive transport are considered. Theoretically-predicted system performance is compared with hybrid simulation and flight test data. Pilot opinion rating, pilot workload, and passenger comfort rating data for the basic and augmented aircraft are included.

Social Mimicry Enhances Mu-Suppression During Action Observation.

PubMed

Hogeveen, Jeremy; Chartrand, Tanya L; Obhi, Sukhvinder S

2015-08-01

During social interactions, there is a tendency for people to mimic the gestures and mannerisms of others, which increases liking and rapport. Psychologists have extensively studied the antecedents and consequences of mimicry at the social level, but the neural basis of this behavior remains unclear. Many researchers have speculated that mimicry is related to activity in the human mirror system (HMS), a network of parietofrontal regions that are involved in both action execution and observation. However, activity of the HMS during reciprocal social interactions involving mimicry has not been demonstrated. Here, we took an electroencephalographic (EEG) index of mirror activity-mu-suppression during action observation-in a pretest/post-test design with 1 of 3 intervening treatments: 1) social interaction in which the participant was mimicked, 2) social interaction without mimicry, or 3) an innocuous computer task, not involving another human agent. The change in mu-suppression from pre- to post-test varied as a function of the intervening treatment, with participants who had been mimicked showing an increase in mu-suppression during the post-treatment action observation session. We propose that this specific modulation of HMS activity as a function of mimicry constitutes the first direct evidence for mirror system involvement in real social mimicry. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Overview of Marshall Space Flight Center Activities for the Combustion Stability Tool Development Program

NASA Technical Reports Server (NTRS)

Kenny, R. J.; Greene, W. D.

2016-01-01

This presentation covers the overall scope, schedule, and activities associated with the NASA - Marshall Space Flight Center (MSFC) involvement with the Combustion Stability Tool Development (CSTD) program. The CSTD program is funded by the Air Force Space & Missile Systems Center; it is approximately two years in duration and; and it is sponsoring MSFC to: design, fabricate, & execute multi-element hardware testing, support Air Force Research Laboratory (AFRL) single element testing, and execute testing of a small-scale, multi-element combustion chamber. Specific MSFC Engineering Directorate involvement, per CSTD-sponsored task, will be outlined. This presentation serves a primer for the corresponding works that provide details of the technical work performed by individual groups within MSFC.

Human Factors Operability Timeline Analysis to Improve the Processing Flow of the Orion Spacecraft

NASA Technical Reports Server (NTRS)

Stambolian, Damon B.; Schlierf, Roland; Miller, Darcy; Posada, Juan; Haddock, Mike; Haddad, Mike; Tran, Donald; Henderon, Gena; Barth, Tim

2011-01-01

This slide presentation reviews the use of Human factors and timeline analysis to have a more efficient and effective processing flow. The solution involved developing a written timeline of events that included each activity within each functional flow block. Each activity had computer animation videos and pictures of the people involved and the hardware. The Human Factors Engineering Analysis Tool (HFEAT) was improved by modifying it to include the timeline of events. The HFEAT was used to define the human factors requirements and design solutions were developed for these requirements. An example of a functional flow block diagram is shown, and a view from one of the animations (i.e., short stack pallet) is shown and explained.

Computational protein design and protein-ligand interaction studies for the improvement of organophosphorus degrading potential of Deinococcus radiodurans.

PubMed

Manoharan, Prabu; Sridhar, J

2018-05-01

The organophosphorus hydrolase enzyme is involved in the catalyzing reaction that involve hydrolysis of organophosphate toxic compounds. An enzyme from Deinococcus radiodurans reported as homologous to phosphotriesterase and show activity against organophosphate. In the past activity of this enzyme is low and efforts made to improve the activity by experimental mutation study. However only very few organophosphates tested against very few catalytic site mutations. In order to improve the catalytic power of the organophosphorus hydrolase enzyme, we carried out systematic functional hotspot based protein engineering strategy. The mutants tested against 46 know organophosphate compounds using molecular docking study. Finally, we carried out an extensive molecular docking study to predict the binding of 46 organophosphate compounds to wild-type protein and mutant organophosphorus hydrolase enzyme. At the end we are able to improve the degrading potential of organophosphorus hydrolase enzyme against organophosphate toxic compounds. This preliminary study and the outcome would be useful guide for the experimental scientist involved in the bioremediation of toxic organophosphate compounds. Copyright © 2018 Elsevier Inc. All rights reserved.

Engineering the Interfaces of Superadsorbing Graphene-Based Electrodes with Gas and Electrolyte to Boost Gas Evolution and Activation Reactions.

PubMed

Zhang, Jun-Jun; Lv, Li-Bing; Zhao, Tian-Jian; Lin, Yun-Xiao; Yu, Qiu-Ying; Su, Juan; Hirano, Shin-Ichi; Li, Xin-Hao; Chen, Jie-Sheng

2018-05-30

Electrochemical gas evolution and activation reactions are complicated processes, involving not only active electrocatalysts but also the interaction among solid electrodes, electrolyte, and gas-phase products and reactants. In this study, multiphase interfaces of superadsorbing graphene-based electrodes were controlled without changing the active centers to significantly facilitate mass diffusion kinetics for superior performance. The achieved in-depth understanding of how to regulate the interfacial properties to promote the electrochemical performance could provide valuable clues for electrode manufacture and for the design of more active electrocatalysts. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Islamic representation and urban space in Banda Aceh: Linking the social and spatial

NASA Astrophysics Data System (ADS)

Istiqamah; Herlily

2018-03-01

Post conflict and tsunami; the city of Banda Aceh is experiencing a massive development as an effort to represent an Islamic city. Some strategic points have been chosen by the municipality to build architectural objects that are considered to represent Islam in the urban space. The issue of such representational practice is the development of neglecting the activities of local communities as users of urban public spaces. The purpose of this design study is to provide an alternative to the urban design of Banda Aceh to represent Islam that is not moving from physical development but by involving community activities. Establish and rediscover the relationship between Islam and urban life in Banda Aceh. This design study uses mental maps of 50 inhabitants of Banda Aceh city of various ages who live in 10 villages around the city center. We use mental maps as a tool to read the daily activities of the community and determine the familiar urban territory with the community. The results of this study will be used to form a Muslim community and present community activities to represent Islam in the urban space.

SERENITY in Air Traffic Management

NASA Astrophysics Data System (ADS)

Felici, Massimo; Meduri, Valentino; Tedeschi, Alessandra; Riccucci, Carlo

This chapter is concerned with the validation of an implementation of the SERENITY Runtime Framework (SRF) tailored for the Air Traffic Management (ATM) domain. It reports our experience in the design and validation phases of a tool, which relies on the SRF in order to support Security and Dependability (S&D) Patterns into work practices. In particular, this chapter pinpoints the activities concerning the identification of S&D Patterns, the design of an ATM prototype and its validation. The validation activities involve qualitative as well as quantitative approaches. These activities as a whole highlight the validation process for adopting S&D Patterns within the ATM domain. Moreover, they stress how S&D Patters enhance and relate to critical features within an industry domain. The empirical results point out that S&D Patterns relate to work practices. Furthermore, they highlight design and validation activities in order to tailor systems relying on S&D Patterns to specific application domains. This strengths and supports the adoption of S&D Patterns in order to address AmI (Ambient Intelligence) requirements (e.g., awareness, proactiveness, resilience, etc.) within the ATM domain.

Treatment Fidelity Among Family Health Promoters Delivering a Physical Activity and Nutrition Intervention to Immigrant and Refugee Families.

PubMed

Bronars, Carrie A; Hanza, Marcelo M; Meiers, Sonja J; Patten, Christi A; Clark, Matthew M; Nigon, Julie A; Weis, Jennifer A; Wieland, Mark L; Sia, Irene G

2017-04-01

Lack of treatment fidelity can be an important source of variation affecting the credibility and utility of outcomes from behavioral intervention research. Development and implementation of a well-designed treatment fidelity plan, especially with research involving underserved populations, requires careful conceptualization of study needs in conjunction with what is feasible in the population. The purpose of this article is to review a fidelity-monitoring plan consistent with the National Institutes of Health Behavior Change Consortium guidelines (e.g., design, training, delivery, receipt, and enactment) for an intervention trial designed to improve physical activity and nutrition among immigrant and refugee families. Description of the fidelity monitoring plan is provided and challenges related to monitoring treatment fidelity in a community-based participatory intervention for immigrant and refugee families are discussed.

Structure-Based Virtual Screening of Protein Tyrosine Phosphatase Inhibitors: Significance, Challenges, and Solutions.

PubMed

Reddy, Rallabandi Harikrishna; Kim, Hackyoung; Cha, Seungbin; Lee, Bongsoo; Kim, Young Jun

2017-05-28

Phosphorylation, a critical mechanism in biological systems, is estimated to be indispensable for about 30% of key biological activities, such as cell cycle progression, migration, and division. It is synergistically balanced by kinases and phosphatases, and any deviation from this balance leads to disease conditions. Pathway or biological activity-based abnormalities in phosphorylation and the type of involved phosphatase influence the outcome, and cause diverse diseases ranging from diabetes, rheumatoid arthritis, and numerous cancers. Protein tyrosine phosphatases (PTPs) are of prime importance in the process of dephosphorylation and catalyze several biological functions. Abnormal PTP activities are reported to result in several human diseases. Consequently, there is an increased demand for potential PTP inhibitory small molecules. Several strategies in structure-based drug designing techniques for potential inhibitory small molecules of PTPs have been explored along with traditional drug designing methods in order to overcome the hurdles in PTP inhibitor discovery. In this review, we discuss druggable PTPs and structure-based virtual screening efforts for successful PTP inhibitor design.

Drug design for ever, from hype to hope

NASA Astrophysics Data System (ADS)

Seddon, G.; Lounnas, V.; McGuire, R.; van den Bergh, T.; Bywater, R. P.; Oliveira, L.; Vriend, G.

2012-01-01

In its first 25 years JCAMD has been disseminating a large number of techniques aimed at finding better medicines faster. These include genetic algorithms, COMFA, QSAR, structure based techniques, homology modelling, high throughput screening, combichem, and dozens more that were a hype in their time and that now are just a useful addition to the drug-designers toolbox. Despite massive efforts throughout academic and industrial drug design research departments, the number of FDA-approved new molecular entities per year stagnates, and the pharmaceutical industry is reorganising accordingly. The recent spate of industrial consolidations and the concomitant move towards outsourcing of research activities requires better integration of all activities along the chain from bench to bedside. The next 25 years will undoubtedly show a series of translational science activities that are aimed at a better communication between all parties involved, from quantum chemistry to bedside and from academia to industry. This will above all include understanding the underlying biological problem and optimal use of all available data.

A review of the design and modification of lactoferricins and their derivatives.

PubMed

Hao, Ya; Yang, Na; Teng, Da; Wang, Xiumin; Mao, Ruoyu; Wang, Jianhua

2018-06-01

Lactoferricin (Lfcin), a multifunction short peptide with a length of 25 residues, is derived from the whey protein lactoferrin by acidic pepsin hydrolysis. It has potent nutritional enhancement, antimicrobial, anticancer, antiviral, antiparasitic, and anti-inflammatory activities. This review describes the research advantages of the above biological functions, with attention to the molecular design and modification of Lfcin. In this examination of design and modification studies, research on the identification of Lfcin active derivatives and crucial amino acid residues is also reviewed. Many strategies for Lfcin optimization have been studied in recent decades, but we mainly introduce chemical modification, cyclization, chimera and polymerization of this peptide. Modifications such as incorporation of D-amino acids, acetylation and/or amidation could effectively improve the activity and stability of these compounds. Due to their wide array of bio-functions and applications, Lfcins have great potential to be developed as biological agents with multiple functions involved with nutritional enhancement, as well as disease preventive and therapeutic effects.

Design and synthesis of novel N-benzylidenesulfonohydrazide inhibitors of MurC and MurD as potential antibacterial agents.

PubMed

Frlan, Rok; Kovac, Andreja; Blanot, Didier; Gobec, Stanislav; Pecar, Slavko; Obreza, Ales

2008-01-11

A series of novel N-benzylidenesulfonohydrazide compounds were designed and synthesized as inhibitors of UDP-N-acetylmuramic acid: L-alanine ligase (MurC) and UDP-N-acetylmuramoyl-L-alanine: D-glutamate ligase (MurD) from E. coli, involved in the biosynthesis of bacterial cell-walls. Some compounds possessed inhibitory activity against both enzymes with IC(50) values as low as 30 microM. In addition, a new, one-pot synthesis of amidobenzaldehydes is reported.

Interfacing Computer-Assisted Drafting and Design with the Building Loads Analysis and System Thermodynamics (BLAST) Program

DTIC Science & Technology

1992-10-01

Manual CI APPENDIX D: Drawing Navigator Field Test D1 DISTRIBUTION Accesion For NTIS CRA&I OTIC TAB Unannouncea JustiteCdtOn By Distribution I "".i•I...methods replace manual methods, the automation will handle the data for the designer, thus reducing error and increasing throughput. However, the two...actively move data from one automation tool (CADD) to the other (the analysis program). This intervention involves a manual rekeying of data already in

Design of novel potent antihyperlipidemic agents with antioxidant/anti-inflammatory properties: exploiting phenothiazine's strong antioxidant activity.

PubMed

Matralis, Alexios N; Kourounakis, Angeliki P

2014-03-27

Because atherosclerosis is an inflammatory process involving a series of pathological events such as dyslipidemia, oxidative stress, and blood clotting mechanisms, we hereby report the synthesis and evaluation of novel compounds in which antioxidant, anti-inflammatory, and squalene synthase (SQS) inhibitory/hypolipidemic activities are combined in simple molecules through design. The coupling of two different pharmacophores afforded compounds 1-12, whose biological profile was markedly improved compared to those of parent lead structures (i.e., the hypolipidemic 2-hydroxy-2-aryl-(benzo)oxa(or thia)zine and the antioxidant phenothiazine). Most derivatives strongly inhibited in vitro microsomal lipid and LDL peroxidation, exhibiting potent free-radical scavenging activity. They further significantly inhibited SQS activity and showed remarkable antidyslipidemic activity in vivo in animal models of acute and high-fat-induced hyperlipidemia. Finally, several compounds showed anti-inflammatory activity in vitro, inhibiting cycloxygenase (COX-1/2) activity. The multimodal properties of the new compounds and especially their combined antioxidant/SQS/COX inhibitory activity render them interesting lead compounds for further evaluation against atherosclerosis.

A primary-school-based study to reduce prevalence of childhood obesity in Catalunya (Spain) - EDAL-Educació en alimentació: study protocol for a randomised controlled trial

PubMed Central

2011-01-01

Background The EdAL (Educació en Alimentació) study is a long-term, nutrition educational, primary-school-based program designed to prevent obesity by promoting a healthy lifestyle that includes dietary recommendations and physical activity. The aims are: 1) to evaluate the effects of a 3-year school-based life-style improvement program on the prevalence of obesity in an area of north-west Mediterranean 2) To design a health-promotion program to be implemented by health-promoter agents (university students) in primary schools. Methods/Design 1) The intervention study is a randomised, controlled, school-based program performed by university-student health-promoter agents. Initial pupil enrolment was in 2006 and continued for 3 years. We considered two clusters (designated as cluster A and cluster B) as the units for randomisation. The first cluster involved 24 schools from Reus and the second involved 14 schools from surrounding towns Cambrils, Salou and Vilaseca combined in order to obtain comparable groups. There are very good communications between schools in each town, and to avoid cross influence of the programs resulting from inter-school dialogue, the towns themselves were the unit for randomisation. Data collected included name, gender, date and place of birth at the start of the program and, subsequently, weight, height, body mass index (BMI) and waist circumference every year for 3 years. Questionnaires on eating and physical activity habits are filled-in by the parents at the start and end of the study and, providing that informed consent is given, the data are analysed on the intention-to-treat basis. The interventions are based on 8 nutritional and physical activity objectives. They are implemented by university students as part of the university curriculum in training health-promoter agents. These 8 objectives are developed in 4 educational activities/year for 3 years (a total of 12 activities; 1 h/activity) performed by the health-promoter agents in primary schools. Control pupils follow their usual activities. 2) Courses on education and promotion of health, within in the curriculum of medicine and health sciences for university students, are designed to train health-promoter agents to administer these activities in primary schools. Discussion This controlled school-based intervention will test the possibility of preventing childhood obesity. Trial registration number ISRCTN: ISRCTN29247645 PMID:21352597

An Airbreathing Launch Vehicle Design with Turbine-Based Low-Speed Propulsion and Dual Mode Scramjet High-Speed Propulsion

NASA Technical Reports Server (NTRS)

Moses, P. L.; Bouchard, K. A.; Vause, R. F.; Pinckney, S. Z.; Ferlemann, S. M.; Leonard, C. P.; Taylor, L. W., III; Robinson, J. S.; Martin, J. G.; Petley, D. H.

1999-01-01

Airbreathing launch vehicles continue to be a subject of great interest in the space access community. In particular, horizontal takeoff and horizontal landing vehicles are attractive with their airplane-like benefits and flexibility for future space launch requirements. The most promising of these concepts involve airframe integrated propulsion systems, in which the external undersurface of the vehicle forms part of the propulsion flowpath. Combining of airframe and engine functions in this manner involves all of the design disciplines interacting at once. Design and optimization of these configurations is a most difficult activity, requiring a multi-discipline process to analytically resolve the numerous interactions among the design variables. This paper describes the design and optimization of one configuration in this vehicle class, a lifting body with turbine-based low-speed propulsion. The integration of propulsion and airframe, both from an aero-propulsive and mechanical perspective are addressed. This paper primarily focuses on the design details of the preferred configuration and the analyses performed to assess its performance. The integration of both low-speed and high-speed propulsion is covered. Structural and mechanical designs are described along with materials and technologies used. Propellant and systems packaging are shown and the mission-sized vehicle weights are disclosed.

The Directed Reading-Thinking Activity (DR-TA) and the Traditional Approach Using Tales of Virtue Based on His Majesty the King's Teaching Concepts in Seventh Grade Students' Reading Comprehension

ERIC Educational Resources Information Center

Chaemsai, Rungruedee; Rattanavich, Saowalak

2016-01-01

This study compares the English reading comprehension and ethical awareness of 7th grade students, when using either a directed reading-thinking activity (DR-TA), or a more traditional approach, involving tales of virtue based on His Majesty the King's teaching concepts. A randomized control group pretest-posttest design was used for the study,…

Assessing facial attractiveness: individual decisions and evolutionary constraints

PubMed Central

Kocsor, Ferenc; Feldmann, Adam; Bereczkei, Tamas; Kállai, János

2013-01-01

Background Several studies showed that facial attractiveness, as a highly salient social cue, influences behavioral responses. It has also been found that attractive faces evoke distinctive neural activation compared to unattractive or neutral faces. Objectives Our aim was to design a face recognition task where individual preferences for facial cues are controlled for, and to create conditions that are more similar to natural circumstances in terms of decision making. Design In an event-related functional magnetic resonance imaging (fMRI) experiment, subjects were shown attractive and unattractive faces, categorized on the basis of their own individual ratings. Results Statistical analysis of all subjects showed elevated brain activation for attractive opposite-sex faces in contrast to less attractive ones in regions that previously have been reported to show enhanced activation with increasing attractiveness level (e.g. the medial and superior occipital gyri, fusiform gyrus, precentral gyrus, and anterior cingular cortex). Besides these, females showed additional brain activation in areas thought to be involved in basic emotions and desires (insula), detection of facial emotions (superior temporal gyrus), and memory retrieval (hippocampus). Conclusions From these data, we speculate that because of the risks involving mate choice faced by women during evolutionary times, selection might have preferred the development of an elaborated neural system in females to assess the attractiveness and social value of male faces. PMID:24693356

A primary-school-based study to reduce prevalence of childhood obesity in Catalunya (Spain)--EDAL-Educació en alimentació: study protocol for a randomised controlled trial.

PubMed

Giralt, Montse; Albaladejo, Rosa; Tarro, Lucia; Moriña, David; Arija, Victoria; Solà, Rosa

2011-02-27

The EdAL (Educació en Alimentació) study is a long-term, nutrition educational, primary-school-based program designed to prevent obesity by promoting a healthy lifestyle that includes dietary recommendations and physical activity.The aims are: 1) to evaluate the effects of a 3-year school-based life-style improvement program on the prevalence of obesity in an area of north-west Mediterranean 2) To design a health-promotion program to be implemented by health-promoter agents (university students) in primary schools. 1) The intervention study is a randomised, controlled, school-based program performed by university-student health-promoter agents. Initial pupil enrolment was in 2006 and continued for 3 years. We considered two clusters (designated as cluster A and cluster B) as the units for randomisation. The first cluster involved 24 schools from Reus and the second involved 14 schools from surrounding towns Cambrils, Salou and Vilaseca combined in order to obtain comparable groups. There are very good communications between schools in each town, and to avoid cross influence of the programs resulting from inter-school dialogue, the towns themselves were the unit for randomisation. Data collected included name, gender, date and place of birth at the start of the program and, subsequently, weight, height, body mass index (BMI) and waist circumference every year for 3 years. Questionnaires on eating and physical activity habits are filled-in by the parents at the start and end of the study and, providing that informed consent is given, the data are analysed on the intention-to-treat basis.The interventions are based on 8 nutritional and physical activity objectives. They are implemented by university students as part of the university curriculum in training health-promoter agents. These 8 objectives are developed in 4 educational activities/year for 3 years (a total of 12 activities; 1 h/activity) performed by the health-promoter agents in primary schools. Control pupils follow their usual activities.2) Courses on education and promotion of health, within in the curriculum of medicine and health sciences for university students, are designed to train health-promoter agents to administer these activities in primary schools. This controlled school-based intervention will test the possibility of preventing childhood obesity. ISRCTN: ISRCTN29247645.

Proteome Characterization of Leaves in Common Bean

PubMed Central

Robison, Faith M.; Heuberger, Adam L.; Brick, Mark A.; Prenni, Jessica E.

2015-01-01

Dry edible bean (Phaseolus vulgaris L.) is a globally relevant food crop. The bean genome was recently sequenced and annotated allowing for proteomics investigations aimed at characterization of leaf phenotypes important to agriculture. The objective of this study was to utilize a shotgun proteomics approach to characterize the leaf proteome and to identify protein abundance differences between two bean lines with known variation in their physiological resistance to biotic stresses. Overall, 640 proteins were confidently identified. Among these are proteins known to be involved in a variety of molecular functions including oxidoreductase activity, binding peroxidase activity, and hydrolase activity. Twenty nine proteins were found to significantly vary in abundance (p-value < 0.05) between the two bean lines, including proteins associated with biotic stress. To our knowledge, this work represents the first large scale shotgun proteomic analysis of beans and our results lay the groundwork for future studies designed to investigate the molecular mechanisms involved in pathogen resistance. PMID:28248269

Empathy for social exclusion involves the sensory-discriminative component of pain: a within-subject fMRI study

PubMed Central

Novembre, Giovanni; Zanon, Marco

2015-01-01

Recent research has shown that experiencing events that represent a significant threat to social bonds activates a network of brain areas associated with the sensory-discriminative aspects of pain. In the present study, we investigated whether the same brain areas are involved when witnessing social exclusion threats experienced by others. Using a within-subject design, we show that an ecologically valid experience of social exclusion recruits areas coding the somatosensory components of physical pain (posterior insular cortex and secondary somatosensory cortex). Furthermore, we show that this pattern of activation not only holds for directly experienced social pain, but also during empathy for social pain. Finally, we report that subgenual cingulate cortex is the only brain area conjointly active during empathy for physical and social pain. This supports recent theories that affective processing and homeostatic regulation are at the core of empathic responses. PMID:24563529

Viewpoints: Teaching and Learning with Games?

ERIC Educational Resources Information Center

Williamson, Ben

2007-01-01

In this article, findings from a recent one-year research project that investigated the use of games in a variety of school settings are described and discussed. The project involved four schools and 12 teachers designing classroom activities around specific games to support learners both within the formal national curriculum and in the context of…

Investigating Plants: Hands-On, Low-Cost Laboratory Exercises in Plant Science.

ERIC Educational Resources Information Center

Sinclair, Thomas R.; Johnson, Marty

This manual describes 14 hands-on exercises for middle school introductory biology courses that are designed to allow all students to be involved in self-discoveries about life and plant life in particular. The exercises were developed to supplement normal classroom activities by allowing students to initiate ongoing projects to investigate the…

Gardening Activities, Education, and Self-Esteem: Learning outside the Classroom

ERIC Educational Resources Information Center

Hoffman, August John; Morales Knight, Luis F.; Wallach, Julie

2007-01-01

Numerous articles have been written about the impact of community-based work and self-esteem, self-efficacy, and gardening in an educational environment. Empirical data suggest that when students have become involved in a group effort designed to improve a school, community, or society, a sense of interdependency and loyalty to that institution…

The Local Fair Exhibit--Still A Valuable Public Relations Tool

ERIC Educational Resources Information Center

Smith, Roswell H., Jr.

1977-01-01

Agricultural exhibits at fairs inform the public about the activities of vocational agriculture programs and Future Farmers of America chapters and are important in gaining public support for vocational agriculture. This article describes some elements involved in a fair exhibit: the exhibit committee, the exhibit design, and the use of color and…

"Enhancing the Creative Process for Learning in Primary Technology Education"

ERIC Educational Resources Information Center

Webster, Alistair; Campbell, Coral; Jane, Beverley

2006-01-01

When undertaking design and technology activities, children are provided with opportunities to create solutions to problems in new and innovative ways. The mental processes involved in the generation of new ideas may be enhanced when children's attention is not focussed and is allowed to wander in a relaxed and uncompetitive environment. Research…

Take a Technowalk: To Learn about Materials & Structures. Springboards for Teaching Series. Teaching Innovations.

ERIC Educational Resources Information Center

Williams, Peter; Jacobson, Saryl

A Technowalk is a walk through the community to explore the technology found there, looking for common materials or particular kinds of structures. Technowalks involve the investigating, designing, testing, trouble-shooting, and problem-solving that the technological process provides. This book provides suggestions for 10 Technowalk activities for…

Take the Time, II. Revised Edition.

ERIC Educational Resources Information Center

Yoast, Richard A., Ed.; And Others

This guide, designed to help people improve the quality of their leisure time, suggests alternative activities which may involve risk or change and may be used by individuals, families, teachers, and treatment personnel. The format is a collection of experiences that people have enjoyed and that make them feel relaxed, refreshed, and good about…

Motor Deficits Following Pediatric Mild Traumatic Brain Injury: Implications for School Psychologists

ERIC Educational Resources Information Center

Davis, Andrew S.; Moore, Brittney; Rice, Valerie; Decker, Scott

2015-01-01

Mild traumatic brain injury (mTBI), sometimes referred to as concussion, is one of the most common acquired neurological problems of childhood. When children return to school following mTBI, school psychologists should be actively involved in the determination of neurocognitive and functional deficits for the purpose of designing strength-based…

MAP Markers: Research and Evaluation of the Mutual Agreement Program. Resource Document No. 5.

ERIC Educational Resources Information Center

Robison, James O.

This report is an evaluation, using randomized experimental/control design, of a program involving negotiated contractual agreements (MAP) between prisoners and parole boards for specific parole dates contingent on performance in work, training and treatment activities. Contracts were generally for less than six months. Both feasibility and…

The Classroom Chefs: A Children's Picture Cookbook for Nutrition Education. Teachers Manual.

ERIC Educational Resources Information Center

Minter, Margaret; And Others

This teacher's manual presents lesson plans and recipes designed for use with preschool children, discusses the need for early nutrition education, and offers suggestions for conducting cooking activities in the classroom. Specific ideas are provided to involve handicapped children in cooking experiences. Nutrition education in the preschool is…

Utilizing a Rat Delayed Implantation Model to Teach Integrative Endocrinology and Reproductive Biology

ERIC Educational Resources Information Center

Geisert, Rodney D.; Smith, Michael F.; Schmelzle, Amanda L.; Green, Jonathan A.

2018-01-01

In this teaching laboratory, the students are directed in an exercise that involves designing and performing an experiment to determine estrogen's role in regulating delayed implantation (diapause) in female rats. To encourage active participation by the students, a discussion question is provided before the laboratory exercise in which each…

Innovation through Collaborative Course Development: Theory and Practice

ERIC Educational Resources Information Center

Aiken, K. Damon; Heinze, Timothy C.; Meuter, Matthew L.; Chapman, Kenneth J.

2016-01-01

A pressing issue for educators is the difficulty in fostering engagement and vesting students in courses. A new pedagogical model labeled Collaborative Course Development (CCD) has evolved as a viable solution. CCD not only allows students to be actively involved in initial course design but also empowers them to make decisions about class…

Why Traditional Expository Teaching-Learning Approaches May Founder? An Experimental Examination of Neural Networks in Biology Learning

ERIC Educational Resources Information Center

Lee, Jun-Ki; Kwon, Yong-Ju

2011-01-01

Using functional magnetic resonance imaging (fMRI), this study investigates and discusses neurological explanations for, and the educational implications of, the neural network activations involved in hypothesis-generating and hypothesis-understanding for biology education. Two sets of task paradigms about biological phenomena were designed:…

The Impact of Project-Based Learning on Pre-Service Teachers' Technology Attitudes and Skills

ERIC Educational Resources Information Center

Alexander, Curby; Knezek, Gerald; Christensen, Rhonda; Tyler-Wood, Tandra; Bull, Glen

2014-01-01

Researchers in this study looked at the effect of content-specific, technology-rich project-based learning activities on EC-8 pre-service teachers' competencies and skills, as well as pre-service teacher's attitudes toward science, technology, engineering and mathematics (STEM). Researchers employed a quantitative design involving participants in…

The Politics of Canadian Space Communication Programs.

ERIC Educational Resources Information Center

Singh, Indu B.; McDaniel, Drew O.

In 1968, the Science Council of Canada recommended that Canada focus its scientific and technological effort on the creation of major programs designed to help solve some of the country's social and economic problems and, specifically, that a space program be initiated. The Canadian decision to become involved in space communication activities was…

Predicting habits of vegetable parenting practices to facilitate the design of change programmes

USDA-ARS?s Scientific Manuscript database

Habit has been defined as the automatic performance of a usual behaviour. The present paper reports the relationships of variables from a Model of Goal Directed Behavior to four scales in regard to parents' habits when feeding their children: habit of (i) actively involving child in selection of veg...

Athletic Facilities: Planning, Designing, and Operating Today's Physical-Education Centers.

ERIC Educational Resources Information Center

Spoor, Dana L.

1998-01-01

Examines what should be featured in an athletic facility, how to plan for the many different sports and activities that will be housed, and how to get the community involved. Areas addressed include planning for locker rooms and storage, flooring and lighting, building code adherence, spectator seating, building security, and outdoor recreation…

Michigan Wetlands: Yours To Protect. A Citizen's Guide to Local Involvement in Wetland Protection. Second Edition.

ERIC Educational Resources Information Center

Cwikiel, Wilfred

This guidebook is designed to assist concerned Michigan citizens, local governments, conservation organizations, landowners, and others in their efforts to initiate wetlands protection activities. Chapter 1 focuses on wetland functions, values, losses, and the urgent need to protect wetland resources. Chapter 2 discusses wetland identification and…

Harnessing Indigenous Basketry Resources for Prenumber and Early Number Work

ERIC Educational Resources Information Center

Ali, Clement Ayarebilla; Davis, Ernest Kofi

2018-01-01

Even though basketry is an age old occupation in Ghana and the world over, it appears mathematics tasks and activities involving the designs and structures have remained unnoticed and inadequately tapped for early school instructions. This qualitative survey therefore, purposively sampled four teachers, two basket artisans and six pupils in the…

Teen Drinking Prevention Program: Teen Action Guide.

ERIC Educational Resources Information Center

Substance Abuse and Mental Health Services Administration (DHHS/PHS), Rockville, MD. Center for Substance Abuse Prevention.

This guide was designed to help teenagers become involved in fun, alcohol-free activities. It provides youth with ideas on how to influence and change the factors that encourage teenage drinking. The guide has four purposes: (1) raise public awareness of the underage drinking crisis; (2) change community norms that encourage underage drinking; (3)…

Directory of Nature Centers and Related Environmental Education Facilities. Third Revision.

ERIC Educational Resources Information Center

National Audubon Society, New York, NY.

This directory is part of a continuing effort to identify facilities actively involved in environmental education. Designed as a guide for the casual visitor as well as the professional person, it aims to stimulate interest in nature centers, improve communication among facilities, and encourage development of new and better ones. This third…

Engagement and Skill Development in Biology Students through Analysis of Art

ERIC Educational Resources Information Center

Milkova, Liliana; Crossman, Colette; Wiles, Stephanie; Allen, Taylor

2013-01-01

An activity involving analysis of art in biology courses was designed with the goals of piquing undergraduates' curiosity, broadening the ways in which college students meaningfully engage with course content and concepts, and developing aspects of students' higher-level thinking skills, such as analysis, synthesis, and evaluation. To meet these…

Manufacturing Systems. Curriculum Guide for Technology Education.

ERIC Educational Resources Information Center

Lloyd, Theodore J.

This curriculum for a 1-semester or 1-year course in manufacturing is designed to give students experience in applying knowledge from other courses and some basic production skills as they become involved in a manufacturing enterprise. Course content is organized around the laboratory activities necessary to organize and operate a process to mass…

To Decrease the Negative Behavior of High School Students by Increasing Pro-Social Behavior.

ERIC Educational Resources Information Center

Cabeza, Catherine

This practicum was designed to reduce the instances of negative behavior exhibited by students in a special education setting. Various interventions were initiated and implemented, such as engaging students in conflict resolution workshops, involving student in extracurricular activities so as to help them use leisure time constructively, and…

Treatment Fidelity among Family Health Promoters Delivering a Physical Activity and Nutrition Intervention to Immigrant and Refugee Families

ERIC Educational Resources Information Center

Bronars, Carrie A.; Hanza, Marcelo M.; Meiers, Sonja J.; Patten, Christi A.; Clark, Matthew M.; Nigon, Julie A.; Weis, Jennifer A.; Wieland, Mark L.; Sia, Irene G.

2017-01-01

Lack of treatment fidelity can be an important source of variation affecting the credibility and utility of outcomes from behavioral intervention research. Development and implementation of a well-designed treatment fidelity plan, especially with research involving underserved populations, requires careful conceptualization of study needs in…

Doing Academic Writing in Education: Connecting the Personal and the Professional

ERIC Educational Resources Information Center

Richards, Janet C.; Miller, Sharon K.

2005-01-01

This clear, reader-friendly book is carefully designed to help readers gain confidence and acquire competence in their academic writing abilities. It focuses on real people as they write and actively involves readers in the writing process. The authors' innovative approach encourages reflection on how professional writing initiatives connect to…

5 CFR 551.215 - Fire protection activities and 7(k) coverage for FLSA pay and exemption determinations.

Code of Federal Regulations, 2014 CFR

2014-01-01

... similar employees involved in fire protection research or in the design and development of fire protection... Protection and Prevention series, including any qualified firefighter who is assigned to perform support... considerations; (ii) Employees in positions properly classified in other series, such as Forestry Technician, for...

5 CFR 551.215 - Fire protection activities and 7(k) coverage for FLSA pay and exemption determinations.

Code of Federal Regulations, 2010 CFR

2010-01-01

... similar employees involved in fire protection research or in the design and development of fire protection... Protection and Prevention series, including any qualified firefighter who is assigned to perform support... considerations; (ii) Employees in positions properly classified in other series, such as Forestry Technician, for...

5 CFR 551.215 - Fire protection activities and 7(k) coverage for FLSA pay and exemption determinations.

Code of Federal Regulations, 2012 CFR

2012-01-01

... similar employees involved in fire protection research or in the design and development of fire protection... Protection and Prevention series, including any qualified firefighter who is assigned to perform support... considerations; (ii) Employees in positions properly classified in other series, such as Forestry Technician, for...

The Use of Outcome Mapping in the Educational Context

ERIC Educational Resources Information Center

Lewis, Anna

2014-01-01

Outcome Mapping is intended to measure the process by which change occurs, it shifts away from the products of the program to focus on changes in behaviors, relationships, actions, and/or activities of the people involved in the treatment program. This process-oriented methodology, most often used in designing and evaluating community development…

Higher Education. Lifelong Learning and Community Service: A Profile of Action and Responsibility.

ERIC Educational Resources Information Center

Champagne, Joseph E.

Two projects, designed to serve as technical input to the developing Texas State Plan for Higher Continuing Education, focused on: (1) enrollment trends and needs, institutional activities, and statewide planning across the nation; and (2) higher education and community services. Both projects involved extensive survey work of institutional visits…

Pakistani Children's Participation in Health Promotion Activities

ERIC Educational Resources Information Center

Ahmed, Shabnam

2011-01-01

This paper examines the effects of a Child-to-Child (CtC) health education programme designed to assist children in Pakistan to greater participation and voice in both their own education and their families' health by empowering them as change agents. The study compares parental involvement in their children's participation in health promotion…

Facilitating Place-Based Environmental Education through Bird Studies: An Action Research Investigation

ERIC Educational Resources Information Center

Can, Özge Kesapli; Lane, Jennie F.; Ateskan, Armagan

2017-01-01

This study involved a workshop designed to support biology teachers in conducting birdwatching activities with their students and to promote place-based environmental education in Turkey. The instruments for collecting data were a workshop questionnaire and interviews. The findings revealed that initial response to the workshop was positive;…

Handbook for Educators Involved in Vocationally Oriented Programming for Moderately Retarded Adolescents.

ERIC Educational Resources Information Center

Pritchett, E. Milo; Pullman, Robert J.

The handbook is designed to help teachers and administrators develop or improve vocationally oriented programs for moderately retarded students. The major topics addressed in the book were identified through a Delphi data gathering approach. Seven sections are arranged in the order that activities should occur in program modification and/or…

Noise Pollution, Teachers' Edition.

ERIC Educational Resources Information Center

O'Donnell, Patrick A.; Lavaroni, Charles W.

One of three in a series about pollution, this teacher's guide for a unit on noise pollution is designed for use in junior high school grades. It offers suggestions for extending the information and activities contained in the textual material for students. Chapter 1 discusses the problem of noise pollution and involves students in processes of…

Parent Power and Public Education Reform: The Experience of Participation in Grassroots Organizing

ERIC Educational Resources Information Center

Mediratta, Kavitha

2013-01-01

This dissertation examines the effects of participation in grassroots organizing on the capacity and commitment of public school parents and community members to engage in future activism. The study used a mixed-methods research design, drawing on qualitative and quantitative data collected from individuals involved in seven exemplar…

Triple Scheme of Learning Support Design for Scientific Discovery Learning Based on Computer Simulation: Experimental Research

ERIC Educational Resources Information Center

Zhang, Jianwei; Chen, Qi; Sun, Yanquing; Reid, David J.

2004-01-01

Learning support studies involving simulation-based scientific discovery learning have tended to adopt an ad hoc strategies-oriented approach in which the support strategies are typically pre-specified according to learners' difficulties in particular activities. This article proposes a more integrated approach, a triple scheme for learning…

Helping Preschoolers Prepare for Writing: Developing Fine Motor Skills

ERIC Educational Resources Information Center

Huffman, J. Michelle; Fortenberry, Callie

2011-01-01

Early childhood is the most intensive period for the development of physical skills. Writing progress depends largely on the development of fine motor skills involving small muscle movements of the hand. Young children need to participate in a variety of developmentally appropriate activities intentionally designed to promote fine motor control.…

School Environment Handbook Part I: Overview and Workshop Activities.

ERIC Educational Resources Information Center

Gillespie, Judith; And Others

This handbook, produced by the School Environmental Impact Program (Indiana) was developed to improve school environments and to create more positive attitudes and behaviors in school participants (all those involved in the school and its environment). It is designed to help in the assessment of school conditions by individuals, groups, or school…

A Computer Simulation Modeling Tool to Assist Colleges in Long-Range Planning. Final Report.

ERIC Educational Resources Information Center

Salmon, Richard; And Others

Long-range planning involves the establishment of educational objectives within a rational philosophy, the design of activities and programs to meet stated objectives, the organization and allocation of resources to implement programs, and the analysis of results in terms of the objectives. Current trends of educational growth and complexity…

Videotex Project Reviews II. Research Report Prepared for OCLC.

ERIC Educational Resources Information Center

Widing, Robert E., II; Talarzyk, W. Wayne

Designed to provide an overview of the nature and focus of activity in the fledgling videotex industry in the United States and Canada, this updated and extended report presents in-depth reviews of 26 projects which reflect the involvement of such industries as publishing, retailing, agriculture, banking, other financial intermediaries,…

Getting a Grant: Sources of Funding and How To Pursue Them

ERIC Educational Resources Information Center

Lum, Christie

2005-01-01

There are many different agencies and organizations which provide funding for those involved in research, community development, education, the provision of health and social services, and other activities. This publication is designed to serve as an introduction for counselors to sources of grant funding and particular grant programs, and to the…

The Popcorn Box Activity and Reasoning about Optimization

ERIC Educational Resources Information Center

Whiteley, Walter J.; Mamolo, Ami

2012-01-01

A well-known optimization problem is the Popcorn Box investigation, which involves a movie theater snack container. The problem has been tailored for classroom investigations by the Ontario Association for Mathematics Education. The exploration was designed for students in grades 9 through 12. A common strategy proposed for algebra students is to…

41 CFR 51-9.701 - Committee rules of conduct.

Code of Federal Regulations, 2012 CFR

2012-07-01

... of conduct. (a) Every Committee member and employee who is involved in the design, development... census or survey or related activity pursuant to the provisions of Title 13 U.S.C.; (5) To a recipient... solely as a statistical research or reporting record, and the record is to be transferred in a form that...

41 CFR 51-9.701 - Committee rules of conduct.

Code of Federal Regulations, 2010 CFR

2010-07-01

... of conduct. (a) Every Committee member and employee who is involved in the design, development... census or survey or related activity pursuant to the provisions of Title 13 U.S.C.; (5) To a recipient... solely as a statistical research or reporting record, and the record is to be transferred in a form that...

41 CFR 51-9.701 - Committee rules of conduct.

Code of Federal Regulations, 2013 CFR

2013-07-01

... of conduct. (a) Every Committee member and employee who is involved in the design, development... census or survey or related activity pursuant to the provisions of Title 13 U.S.C.; (5) To a recipient... solely as a statistical research or reporting record, and the record is to be transferred in a form that...