38 CFR 3.812 - Special allowance payable under section 156 of Pub. L. 97-377.

Code of Federal Regulations, 2011 CFR

2011-07-01

... consideration, and death on active duty subsequent to August 12, 1981, is qualifying provided that the death... payment rate—(1) Basic entitlement rate. A basic entitlement rate will be computed for each eligible...-377 using data to be provided by the Social Security Administration. This basic entitlement rate will...

Perspective on computational and structural aspects of kinase discovery from IPK2014.

PubMed

Martin, Eric; Knapp, Stefan; Engh, Richard A; Moebitz, Henrik; Varin, Thibault; Roux, Benoit; Meiler, Jens; Berdini, Valerio; Baumann, Alexander; Vieth, Michal

2015-10-01

Recent advances in understanding the activity and selectivity of kinase inhibitors and their relationships to protein structure are presented. Conformational selection in kinases is studied from empirical, data-driven and simulation approaches. Ligand binding and its affinity are, in many cases, determined by the predetermined active and inactive conformation of kinases. Binding affinity and selectivity predictions highlight the current state of the art and advances in computational chemistry as it applies to kinase inhibitor discovery. Kinome wide inhibitor profiling and cell panel profiling lead to a better understanding of selectivity and allow for target validation and patient tailoring hypotheses. This article is part of a Special Issue entitled: Inhibitors of Protein Kinases. Copyright © 2015 Elsevier B.V. All rights reserved.

77 FR 76406 - Criteria and Procedures for Proposed Assessment of Civil Penalties; Inflation Adjustment

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-28

... discretion. MSHA is required to perform mathematical computations based on published cost-of-living data and... altering the budgetary impact of entitlements or the rights of entitlement recipients, or raising novel...

Grandparents' entitlements and obligations.

PubMed

Draper, Heather

2013-07-01

In this article, it is argued that grandparents' obligations originate from parental obligations (i.e from the relationship they have with their children, the parents of their grandchildren) and not from the role of grandparent per se, and any entitlements flow from the extent to which these obligations are met. The position defended is, therefore, that grandparents qua grandparents are not entitled to form or continue relationships with their grandchildren. A continuation of grandparent-grandchildren relationships may be in the interests of children, but the grandparental nature of the relationship is not decisive. What counts is the extent to which relationships children have with any adults who are not their parents are is significant to them. Sometimes, however, grandparents become parents or co-parents of their grandchildren. They then gain parental rights, and as such are as entitled, ceteris parius, as any parent to expect their relationship with the child to continue. The issue of grandparents' entitlements can come to the fore when parents separate, and grandparents are unhappy with the access they have to their grandchildren. Grandparents' obligations may become a particular issue when parents die, struggle, or fail to care for their children. This article focuses particularly on these kinds of circumstances. © 2013 John Wiley & Sons Ltd.

GRANDPARENTS' ENTITLEMENTS AND OBLIGATIONS

PubMed Central

Draper, Heather

2013-01-01

In this article, it is argued that grandparents' obligations originate from parental obligations (i.e from the relationship they have with their children, the parents of their grandchildren) and not from the role of grandparent per se, and any entitlements flow from the extent to which these obligations are met. The position defended is, therefore, that grandparents qua grandparents are not entitled to form or continue relationships with their grandchildren. A continuation of grandparent-grandchildren relationships may be in the interests of children, but the grandparental nature of the relationship is not decisive. What counts is the extent to which relationships children have with any adults who are not their parents are is significant to them. Sometimes, however, grandparents become parents or co-parents of their grandchildren. They then gain parental rights, and as such are as entitled, ceteris parius, as any parent to expect their relationship with the child to continue. The issue of grandparents' entitlements can come to the fore when parents separate, and grandparents are unhappy with the access they have to their grandchildren. Grandparents' obligations may become a particular issue when parents die, struggle, or fail to care for their children. This article focuses particularly on these kinds of circumstances. PMID:23718643

Molecular modeling of biomolecules by paramagnetic NMR and computational hybrid methods.

PubMed

Pilla, Kala Bharath; Gaalswyk, Kari; MacCallum, Justin L

2017-11-01

The 3D atomic structures of biomolecules and their complexes are key to our understanding of biomolecular function, recognition, and mechanism. However, it is often difficult to obtain structures, particularly for systems that are complex, dynamic, disordered, or exist in environments like cell membranes. In such cases sparse data from a variety of paramagnetic NMR experiments offers one possible source of structural information. These restraints can be incorporated in computer modeling algorithms that can accurately translate the sparse experimental data into full 3D atomic structures. In this review, we discuss various types of paramagnetic NMR/computational hybrid modeling techniques that can be applied to successful modeling of not only the atomic structure of proteins but also their interacting partners. This article is part of a Special Issue entitled: Biophysics in Canada, edited by Lewis Kay, John Baenziger, Albert Berghuis and Peter Tieleman. Copyright © 2017 Elsevier B.V. All rights reserved.

78 FR 31398 - Visas: Documentation of Immigrants Under the Immigration and Nationality Act, as Amended

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-24

... Immigrants Under the Immigration and Nationality Act, as Amended AGENCY: Department of State. ACTION: Final... method of recording an alien's entitlement to an immigrant visa classification. Due to the availability of automated systems at all immigrant visa-issuing posts, this entitlement is now recorded...

20 CFR 625.13 - Restrictions on entitlement; disqualification.

Code of Federal Regulations, 2010 CFR

2010-04-01

... DISASTER UNEMPLOYMENT ASSISTANCE § 625.13 Restrictions on entitlement; disqualification. (a) Income reductions. The amount of DUA payable to an individual for a week of unemployment, as computed pursuant to... wages due to illness or disability; (2) A supplemental unemployment benefit pursuant to a collective...

20 CFR 625.13 - Restrictions on entitlement; disqualification.

Code of Federal Regulations, 2012 CFR

2012-04-01

... DISASTER UNEMPLOYMENT ASSISTANCE § 625.13 Restrictions on entitlement; disqualification. (a) Income reductions. The amount of DUA payable to an individual for a week of unemployment, as computed pursuant to... wages due to illness or disability; (2) A supplemental unemployment benefit pursuant to a collective...

20 CFR 625.13 - Restrictions on entitlement; disqualification.

Code of Federal Regulations, 2011 CFR

2011-04-01

... DISASTER UNEMPLOYMENT ASSISTANCE § 625.13 Restrictions on entitlement; disqualification. (a) Income reductions. The amount of DUA payable to an individual for a week of unemployment, as computed pursuant to... wages due to illness or disability; (2) A supplemental unemployment benefit pursuant to a collective...

20 CFR 625.13 - Restrictions on entitlement; disqualification.

Code of Federal Regulations, 2014 CFR

2014-04-01

... DISASTER UNEMPLOYMENT ASSISTANCE § 625.13 Restrictions on entitlement; disqualification. (a) Income reductions. The amount of DUA payable to an individual for a week of unemployment, as computed pursuant to... wages due to illness or disability; (2) A supplemental unemployment benefit pursuant to a collective...

20 CFR 625.13 - Restrictions on entitlement; disqualification.

Code of Federal Regulations, 2013 CFR

2013-04-01

... DISASTER UNEMPLOYMENT ASSISTANCE § 625.13 Restrictions on entitlement; disqualification. (a) Income reductions. The amount of DUA payable to an individual for a week of unemployment, as computed pursuant to... wages due to illness or disability; (2) A supplemental unemployment benefit pursuant to a collective...

Intellectual Freedom and Economic Sufficiency as Educational Entitlements.

ERIC Educational Resources Information Center

Morse, Jane Fowler

2001-01-01

Using the theories of John Stuart Mill and Karl Marx, this article supports the educational entitlements of intellectual freedom and economic sufficiency. Explores these issues in reference to their implications for teaching, the teaching profession and its training. Concludes that ideas cannot be controlled by the interests of the dominant class.…

75 FR 3163 - Vocational Rehabilitation and Employment Program-Basic Entitlement; Effective Date of Induction...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-20

... implemented changes to services provided under 38 U.S.C. chapter 31, which resulted from a court decision and..., for vocational rehabilitation basic entitlement determinations resulting from the Veterans' Benefits... issuing any rule that may result in the expenditure by State, local, and Tribal governments, in the...

TESL Reporter, Vol. 4, No. 2.

ERIC Educational Resources Information Center

Pack, Alice C., Ed.

This issue of "TESL Reporter" presents results of a 1970 English as a Second Language (ESL) textbook survey conducted by the English Language Institute and reported by Alice C. Pack; an article by Julene Evans entitled "Why TESL?"; and an article by Yao Shen entitled "Supplementation of Opposites in Simple Predicate Expansion." Of the 1,200 mailed…

A Module for the Administration of Homebound Instructional Programs

ERIC Educational Resources Information Center

Wasserman, Lewis

2008-01-01

Special program and other school administrators regularly confront the issue of whether students under their charge are entitled to receive homebound instruction and if so, what procedures and criteria they should apply in coming to a proper decision. Where a student is entitled to such services the administrator must decide what subjects must be…

ERCMExpress. Volume 3, Issue 4

ERIC Educational Resources Information Center

Taymans, Mary Frances; McDonald, Dale

2007-01-01

The Emergency Response and Crisis Management (ERCM) Technical Assistance Center's "ERCMExpress" is a newsletter that provides comprehensive information on key issues in school emergency management. This issue, entitled "Emergency Management Opportunities and Challenges for Non-Public Schools," examines integrating non-public…

77 FR 38275 - Notice of Intent To Grant Exclusive Patent License; Emerging Growth Enterprise LLC

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-27

..., nonassignable, exclusive license to practice in the field of fire fighting foam discharge and suppression... November 6, 2007) and entitled, ``Nofoam system for testing a foam delivery system on a vehicle'', No. 7,293,478 (Issued November 13, 2007) and entitled ``Method for testing a foam delivery system on a...

ProteinInferencer: Confident protein identification and multiple experiment comparison for large scale proteomics projects.

PubMed

Zhang, Yaoyang; Xu, Tao; Shan, Bing; Hart, Jonathan; Aslanian, Aaron; Han, Xuemei; Zong, Nobel; Li, Haomin; Choi, Howard; Wang, Dong; Acharya, Lipi; Du, Lisa; Vogt, Peter K; Ping, Peipei; Yates, John R

2015-11-03

Shotgun proteomics generates valuable information from large-scale and target protein characterizations, including protein expression, protein quantification, protein post-translational modifications (PTMs), protein localization, and protein-protein interactions. Typically, peptides derived from proteolytic digestion, rather than intact proteins, are analyzed by mass spectrometers because peptides are more readily separated, ionized and fragmented. The amino acid sequences of peptides can be interpreted by matching the observed tandem mass spectra to theoretical spectra derived from a protein sequence database. Identified peptides serve as surrogates for their proteins and are often used to establish what proteins were present in the original mixture and to quantify protein abundance. Two major issues exist for assigning peptides to their originating protein. The first issue is maintaining a desired false discovery rate (FDR) when comparing or combining multiple large datasets generated by shotgun analysis and the second issue is properly assigning peptides to proteins when homologous proteins are present in the database. Herein we demonstrate a new computational tool, ProteinInferencer, which can be used for protein inference with both small- or large-scale data sets to produce a well-controlled protein FDR. In addition, ProteinInferencer introduces confidence scoring for individual proteins, which makes protein identifications evaluable. This article is part of a Special Issue entitled: Computational Proteomics. Copyright © 2015. Published by Elsevier B.V.

14 CFR 21.257 - Type certificates: issue.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Type certificates: issue. 21.257 Section 21.257 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT... certificates: issue. An applicant is entitled to a type certificate for a product manufactured under a...

14 CFR 21.257 - Type certificates: issue.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Type certificates: issue. 21.257 Section 21.257 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT... certificates: issue. An applicant is entitled to a type certificate for a product manufactured under a...

75 FR 8313 - Notice of Availability of Government-Owned Inventions; Available for Licensing

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-24

... entitled ``Composition and process for removing and preventing mildew and fungal growth'' issued on... and preventing mildew and fungal growth'' issued on December 8, 2009. ADDRESSES: Requests for data and...

IVHS institutional issues and case studies : ADVANCE case study

DOT National Transportation Integrated Search

1994-04-01

This operational test case study is one of six performed in response to a Volpe National Transportation Systems Center technical task directive (TTD) to Science Applications International Corporation (SAIC) entitled, IVHS Institutional Issues and ...

Introduction

Treesearch

Sheila E. Ward; David Boshier; James Grogan

2008-01-01

This special issue of Forest Ecology and Management addresses management issues for the tropical timber species of the Meliaceae. The concept for this issue originated from a technical session entitled ..Sustainable management of highvalue timber species of the Meliaceae: a global perspective.., held at the 2005 World Congress of the International Union of Forest...

Shortfall online: The development of an educational computer game for teaching sustainable engineering to Millennial Generation students

NASA Astrophysics Data System (ADS)

Gennett, Zachary Andrew

Millennial Generation students bring significant learning and teaching challenges to the classroom, because of their unique learning styles, breadth of interests related to social and environmental issues, and intimate experiences with technology. As a result, there has been an increased willingness at many universities to experiment with pedagogical strategies that depart from a traditional "learning by listening" model, and move toward more innovative methods involving active learning through computer games. In particular, current students typically express a strong interest in sustainability in which economic concerns must be weighed relative to environmental and social responsibilities. A game-based setting could prove very effective for fostering an operational understanding of these tradeoffs, and especially the social dimension which remains largely underdeveloped relative to the economic and environmental aspects. Through an examination of the educational potential of computer games, this study hypothesizes that to acquire the skills necessary to manage and understand the complexities of sustainability, Millennial Generation students must be engaged in active learning exercises that present dynamic problems and foster a high level of social interaction. This has led to the development of an educational computer game, entitled Shortfall, which simulates a business milieu for testing alternative paths regarding the principles of sustainability. This study examines the evolution of Shortfall from an educational board game that teaches the principles of environmentally benign manufacturing, to a completely networked computer game, entitled Shortfall Online that teaches the principles of sustainability. A capital-based theory of sustainability is adopted to more accurately convey the tradeoffs and opportunity costs among economic prosperity, environmental preservation, and societal responsibilities. While the economic and environmental aspects of sustainability have received considerable attention in traditional pedagogical approaches, specific focus is provided for the social dimension of sustainability, as it had remained largely underdeveloped. To measure social sustainability and provide students with an understanding of its significance, a prospective metric utilizing a social capital peer-evaluation survey, unique to Shortfall, is developed.

77 FR 39498 - Guidances for Industry and Food and Drug Administration Staff: Computer-Assisted Detection...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-03

...] Guidances for Industry and Food and Drug Administration Staff: Computer-Assisted Detection Devices Applied... Clinical Performance Assessment: Considerations for Computer-Assisted Detection Devices Applied to... guidance, entitled ``Computer-Assisted Detection Devices Applied to Radiology Images and Radiology Device...

Protection of Computer Programs--A Dilemma.

ERIC Educational Resources Information Center

Carnahan, William H.

Computer programs, as legitimate original inventions or creative written expressions, are entitled to patent or copyright protection. Understanding the legal implications of this concept is crucial to both computer programmers and their employers in our increasingly computer-oriented way of life. Basically the copyright or patent procedure…

Molecular simulation aspects of amyloid peptides at membrane interface.

PubMed

Liu, Yonglan; Ren, Baiping; Zhang, Yanxian; Sun, Yan; Chang, Yung; Liang, Guizhao; Xu, Lijian; Zheng, Jie

2018-02-06

The interactions of amyloid peptides with cell membranes play an important role in maintaining the integrity and functionality of cell membrane. A thorough molecular-level understanding of the structure, dynamics, and interactions between amyloid peptides and cell membranes is critical to amyloid aggregation and toxicity mechanisms for the bench-to-bedside applications. Here we review the most recent computational studies of amyloid peptides at model cell membranes. Different mechanisms of action of amyloid peptides on/in cell membranes, targeted by different computational techniques at different lengthscales and timescales, are rationally discussed. Finally, we have proposed some new insights into the remaining challenges and perspectives for future studies to improve our understanding of the activity of amyloid peptides associated with protein-misfolding diseases. This article is part of a Special Issue entitled: Protein Aggregation and Misfolding at the Cell Membrane Interface edited by Ayyalusamy Ramamoorthy. Copyright © 2018 Elsevier B.V. All rights reserved.

20 CFR 228.20 - Reduction for an employee annuity.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Reduction for an employee annuity. 228.20... COMPUTATION OF SURVIVOR ANNUITIES The Tier I Annuity Component § 228.20 Reduction for an employee annuity. (a) General. If an individual is entitled to an annuity as a survivor, and is also entitled to an employee...

Controlled vocabularies and ontologies in proteomics: Overview, principles and practice☆

PubMed Central

Mayer, Gerhard; Jones, Andrew R.; Binz, Pierre-Alain; Deutsch, Eric W.; Orchard, Sandra; Montecchi-Palazzi, Luisa; Vizcaíno, Juan Antonio; Hermjakob, Henning; Oveillero, David; Julian, Randall; Stephan, Christian; Meyer, Helmut E.; Eisenacher, Martin

2014-01-01

This paper focuses on the use of controlled vocabularies (CVs) and ontologies especially in the area of proteomics, primarily related to the work of the Proteomics Standards Initiative (PSI). It describes the relevant proteomics standard formats and the ontologies used within them. Software and tools for working with these ontology files are also discussed. The article also examines the “mapping files” used to ensure correct controlled vocabulary terms that are placed within PSI standards and the fulfillment of the MIAPE (Minimum Information about a Proteomics Experiment) requirements. This article is part of a Special Issue entitled: Computational Proteomics in the Post-Identification Era. Guest Editors: Martin Eisenacher and Christian Stephan. PMID:23429179

14 CFR 125.27 - Issue of certificate.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Issue of certificate. 125.27 Section 125.27... AND OPERATORS FOR COMPENSATION OR HIRE: CERTIFICATION AND OPERATIONS CERTIFICATION AND OPERATIONS... Requirements § 125.27 Issue of certificate. (a) An applicant for a certificate under this subpart is entitled...

Using Service Learning in a Course Entitled "Biology of Women" to Promote Student Engagement and Awareness of Community Needs and Resources

ERIC Educational Resources Information Center

Bauer-Dantoin, Angela C.

2008-01-01

Service learning projects were incorporated into the curriculum of an undergraduate course entitled "Biology of Women". The goals of the service learning projects were: 1) to provide students with the opportunity to consider issues pertaining to human biology in real-world settings; 2) to foster student engagement with the community; and…

Eyeglass Benefits: Consideration of Frame of Choice for Retired Service Members

DTIC Science & Technology

2009-04-20

20100329217 t. ABSTRACT ’he Department of Defense (DoD) provides basic eyewear to our nation’s military members. .Ithough not specifically entitled under...Title X, military retirees historically also receive tandard issue eyewear . The military’s Frame of Choice (FOC) program currently benefits the...current fiscal environment. . SUBJECT TERMS ^eglasses, Frame of Choice, Retiree, Service Members, Entitlements, Eyewear , snefit, Optometry, Optical

77 FR 51571 - Certain Wireless Communication Devices, Portable Music and Data Processing Devices, Computers...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-24

... Music and Data Processing Devices, Computers, and Components Thereof; Notice of Receipt of Complaint... complaint entitled Wireless Communication Devices, Portable Music and Data Processing Devices, Computers..., portable music and data processing devices, computers, and components thereof. The complaint names as...

Explorations in Space and Time: Computer-Generated Astronomy Films

ERIC Educational Resources Information Center

Meeks, M. L.

1973-01-01

Discusses the use of the computer animation technique to travel through space and time and watch models of astronomical systems in motion. Included is a list of eight computer-generated demonstration films entitled Explorations in Space and Time.'' (CC)

78 FR 18353 - Guidance for Industry: Blood Establishment Computer System Validation in the User's Facility...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-26

...; (Formerly FDA-2007D-0393)] Guidance for Industry: Blood Establishment Computer System Validation in the User... Industry: Blood Establishment Computer System Validation in the User's Facility'' dated April 2013. The... document entitled ``Guidance for Industry: Blood Establishment Computer System Validation in the User's...

Compression strength of composite primary structural components

NASA Technical Reports Server (NTRS)

Johnson, Eric R.

1993-01-01

Two projects are summarized. The first project is entitled 'Stiffener Crippling Inititated by Delaminations' and its objective is to develop a computational model of the stiffener specimens that includes the capability to predict the interlaminar stress response at the flange free edge in postbuckling. The second is entitled 'Pressure Pillowing of an Orthogonally Stiffened Cylindrical Shell'. A paper written on this project is included.

Design Process of a Goal-Based Scenario on Computing Fundamentals

ERIC Educational Resources Information Center

Beriswill, Joanne Elizabeth

2014-01-01

In this design case, an instructor developed a goal-based scenario (GBS) for undergraduate computer fundamentals students to apply their knowledge of computer equipment and software. The GBS, entitled the MegaTech Project, presented the students with descriptions of the everyday activities of four persons needing to purchase a computer system. The…

Doing Local History.

ERIC Educational Resources Information Center

Ohrn, Deborah Gore, Ed.

1992-01-01

This theme issue contains articles about the importance of learning local history. The lead article includes historical information about three Iowa cities: Council Bluffs, Waterloo, and Jefferson. Other features in this issue are entitled: "Iowa Kids Talk,""Digging Into Local History,""Goldie's Top Ten News Stories";…

20 CFR 404.233 - Adjustment of your guaranteed alternative when you become entitled after age 62.

Code of Federal Regulations, 2010 CFR

2010-04-01

... at the time you reach age 62, we adjust the guaranteed alternative computed for you under § 404.232... amounts that go into effect in the year you reach age 62 and in years up through the year you become... since December 1978.) Example: Mr. C reaches age 62 in January 1981 and becomes entitled to old-age...

20 CFR 404.233 - Adjustment of your guaranteed alternative when you become entitled after age 62.

Code of Federal Regulations, 2011 CFR

2011-04-01

... at the time you reach age 62, we adjust the guaranteed alternative computed for you under § 404.232... amounts that go into effect in the year you reach age 62 and in years up through the year you become... since December 1978.) Example: Mr. C reaches age 62 in January 1981 and becomes entitled to old-age...

Computers in Composition Instruction.

ERIC Educational Resources Information Center

Shostak, Robert, Ed.

This volume consists of nine conference papers and journal articles concerned with microcomputer applications in the teaching of writing. After a general introduction entitled "Computer-Assisted Composition Instruction: The State of the Art," by Robert Shostak, four papers are devoted to how computers may help with the writing process. In…

76 FR 26290 - Science Advisory Board Staff Office; Notification of a Public Teleconference of the Chartered...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-06

... report entitled ``SAB Review of EPA's Reanalysis of Key Issues Related to Dioxin Toxicity and Response to... of EPA's Reanalysis of Key Issues Related to Dioxin Toxicity and Response to NAS Comments.'' The SAB... Reanalysis of Key Issues Related to Dioxin Toxicity and Response to NAS Comments.'' To conduct this review...

75 FR 62514 - Notice of Availability of Report on Data Access and Privacy Issues Related to Smart Grid...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-12

... DEPARTMENT OF ENERGY Notice of Availability of Report on Data Access and Privacy Issues Related to... report entitled, ``Data Access and Privacy Issues Related to Smart Grid Technologies.'' In this report... meeting conducted during the preparation of the report. This report responds to recommendations for DOE...

Computational chemistry research

NASA Technical Reports Server (NTRS)

Levin, Eugene

1987-01-01

Task 41 is composed of two parts: (1) analysis and design studies related to the Numerical Aerodynamic Simulation (NAS) Extended Operating Configuration (EOC) and (2) computational chemistry. During the first half of 1987, Dr. Levin served as a member of an advanced system planning team to establish the requirements, goals, and principal technical characteristics of the NAS EOC. A paper entitled 'Scaling of Data Communications for an Advanced Supercomputer Network' is included. The high temperature transport properties (such as viscosity, thermal conductivity, etc.) of the major constituents of air (oxygen and nitrogen) were correctly determined. The results of prior ab initio computer solutions of the Schroedinger equation were combined with the best available experimental data to obtain complete interaction potentials for both neutral and ion-atom collision partners. These potentials were then used in a computer program to evaluate the collision cross-sections from which the transport properties could be determined. A paper entitled 'High Temperature Transport Properties of Air' is included.

Formation of Teachers as Leaders: Response to the Articles in This Special Issue

ERIC Educational Resources Information Center

Frick, William C.; Browne-Ferrigno, Tricia

2016-01-01

This article contains a response to three manuscripts that are part of the "JRLE" special issue entitled Developing and Empowering Teacher Leaders for Collective Leadership. Discussion of the articles, lessons learned, and implications for teacher leadership development are discussed.

A Rainbow of Qualitative Approaches and Concerns.

ERIC Educational Resources Information Center

Fetterman, David M.

1987-01-01

Reviews the seven papers presented at a symposium entitled "Perennial Issues in Qualitative Research," part of the Annual Meeting of the American Educational Research Association (San Francisco, California, 1986), and included in this issue. Discusses the demonstrated usefulness of qualitative methods in educational research, and also…

77 FR 27078 - Certain Electronic Devices, Including Mobile Phones and Tablet Computers, and Components Thereof...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-08

... Phones and Tablet Computers, and Components Thereof; Notice of Receipt of Complaint; Solicitation of... entitled Certain Electronic Devices, Including Mobile Phones and Tablet Computers, and Components Thereof... the United States after importation of certain electronic devices, including mobile phones and tablet...

The Communicative Computer Compares: A CALL Design Project for Elementary French.

ERIC Educational Resources Information Center

Kyle, Patricia J.

A computer lesson entitled "Aux Jeux Olympiques" (To the Olympic Games) simulates an ongoing situational dialog between the French student and the PLATO computer system. It offers an international setting for functional learning exercises focusing on students' understanding and use of comparative constructions, selected verbs, and other linguistic…

A Computer Program for Estimating True-Score Distributions and Graduating Observed-Score Distributions

ERIC Educational Resources Information Center

Wingersky, Marilyn S.; and others

1969-01-01

One in a series of nine articles in a section entitled, "Electronic Computer Program and Accounting Machine Procedures. Research supported in part by contract Nonr-2752(00) from the Office of Naval Research.

Teaching Research Integrity and Bioethics to Science Undergraduates

ERIC Educational Resources Information Center

Turrens, Julio F.

2005-01-01

Undergraduate students in the Department of Biomedical Sciences at the University of South Alabama, Mobile, are required to take a course entitled "Issues in Biomedical Sciences," designed to increase students' awareness about bioethical questions and issues concerning research integrity. This paper describes the main features of this…

AGING AND TOXIC RESPONSE: ISSUES RELEVANT TO RISK ASSESSMENT (FINAL)

EPA Science Inventory

EPA has released a final report entitled, Aging and Toxic Response: Issues Relevant to Risk Assessment. This document contributes to the Agency's efforts to better understand the physiology of aging in order to protect the health of older persons, and identifies several d...

Protein dynamics and enzyme catalysis: insights from simulations.

PubMed

McGeagh, John D; Ranaghan, Kara E; Mulholland, Adrian J

2011-08-01

The role of protein dynamics in enzyme catalysis is one of the most active and controversial areas in enzymology today. Some researchers claim that protein dynamics are at the heart of enzyme catalytic efficiency, while others state that dynamics make no significant contribution to catalysis. What is the biochemist - or student - to make of the ferocious arguments in this area? Protein dynamics are complex and fascinating, as molecular dynamics simulations and experiments have shown. The essential question is: do these complex motions have functional significance? In particular, how do they affect or relate to chemical reactions within enzymes, and how are chemical and conformational changes coupled together? Biomolecular simulations can analyse enzyme reactions and dynamics in atomic detail, beyond that achievable in experiments: accurate atomistic modelling has an essential part to play in clarifying these issues. This article is part of a Special Issue entitled: Protein Dynamics: Experimental and Computational Approaches. Copyright © 2010 Elsevier B.V. All rights reserved.

Humanities Perspectives on Technology Program: Science, Technology & Society Program. Lehigh University, 1977-80.

ERIC Educational Resources Information Center

Cutcliffe, Stephen H., Ed.

Newsletter issues pertaining to Lehigh University's Humanities Perspectives on Technology (HPT) Program, which was renamed the Science, Technology and Society Program, are presented. Additionally, a newsletter article excerpt entitled "Elements of Technology in a Liberal Education" is included. Two 1977 issues of "HRP News,"…

76 FR 70680 - Small Business Size Standards: Real Estate and Rental and Leasing

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-15

... industries and one sub- industry in North American Industry Classification System (NAICS) Sector 53, Real... industries grouped by NAICS Sector. SBA issued a White Paper entitled ``Size Standards Methodology'' and published in the October 21, 2009 issue of the Federal Register. That ``Size Standards Methodology'' is...

The Affective Side: Gifted Identification and the Call to Advocacy.

ERIC Educational Resources Information Center

Strop, Jean

2003-01-01

This article lists common pitfalls in parents' gifted advocacy attempts: believing exceptionality is synonymous with entitlement; responding to stated boredom without determining the meaning; waiting for a crisis before advocating; pushing for a response before agreeing on the issue; and advocating from their own issues. Strategies for developing…

Water, water quality and health (Chapter 3 in Book entitled: Environmental Tracking for Public Health Surveillance).

EPA Science Inventory

This chapter identifies the role environmental tracking plays in identifying public health water hazard and water quality issues. It outlines public health issues to be examined and provides an integrated overview of water and diseases by combining knowledge of the hydrological ...

Identity Development Process and Content: Toward an Integrated and Contextualized Science of Identity

ERIC Educational Resources Information Center

Galliher, Renee V.; Rivas-Drake, Deborah; Dubow, Eric F.

2017-01-01

This introductory summary provides an overview of the content of the special issue entitled "Identity Development Process and Content: Toward an Integrated and Contextualized Science of Identity." The 16 theoretical and empirical articles that comprise this special issue were selected to highlight innovative methodologies, theoretical…

Optimizing Wartime Materiel Delivery: An Overview of DoD containerization. Volume 2. Framework for Action to Address DoD Containerization Issues

DOT National Transportation Integrated Search

1988-10-01

This second volume of the study entitled, Optimizing Wartime Materiel Delivery: An Overview of DOD Containerization Efforts, -outlines a framework for action to address containerization issues identified in Volume I. The objectives of the study inclu...

Testing Programs in Schools: What's New? A Special Issue.

ERIC Educational Resources Information Center

Walter, L. James; And Others

1981-01-01

This special issue of "Catalyst", entitled Testing Programs in Schools: What's New?, was published jointly by the Nebraska Council of School Administrators and the Nebraska Association for Supervision and Curriculum. The articles emphasize desirability of designing testing programs to meet the information needs of educators and the…

Unlearning Whiteness, Rethinking Race Issues in Graduate Music Education

ERIC Educational Resources Information Center

Bradley, Deborah; Golner, Ronald; Hanson, Sarah

2007-01-01

This paper examines the experiences of music education graduate students and their instructor during a fifteen-week seminar course entitled "Race issues in music teaching." Excerpts from students' journal entries and the instructor's responses to those journals are constructed in this paper as dialogue vignettes which provide insight…

PREFACE OF SPECIAL ISSUE OF AEROSOL SCIENCE AND TECHNOLOGY FOR PARTICULATE MATTER SUPERSITES PROGRAM AND RELATED STUDIES

EPA Science Inventory

This article is the preface or editors note to a dedicated issue of Aerosol Science and Technology, journal of the American Association for Aerosol Research. It includes a selection of scientific papers from the specialty conference entitled, "Particulate Matter Supersites ...

Papers on Theoretical Issues in Health Education.

ERIC Educational Resources Information Center

California Univ., Berkeley. School of Public Health.

This document is a collection of 17 papers on theoretical issues in health education presented at the Dorothy Nyswander International Symposium. The introduction, entitled "Theory and Practice in Health Education: A Synthesis," attempts to highlight some of the features of these papers and their relevance for health education practice. The papers…

77 FR 8223 - Notice of Availability for Exclusive, Non-Exclusive, or Partially-Exclusive Licensing of an...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-14

..., or Partially-Exclusive Licensing of an Invention Concerning a Computer Controlled System for Laser... provides a computer controlled system for laser energy delivery to the retina. Information is received from... Application Serial No. 13/130,380, entitled ``Computer Controlled System for Laser Energy Delivery to the...

77 FR 34941 - Privacy Act of 1974; Notice of a Computer Matching Program

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-12

...; Notice of a Computer Matching Program AGENCY: Defense Manpower Data Center, DoD. ACTION: Notice of a... computer matching program are the Department of Veterans Affairs (VA) and the Defense Manpower Data Center... identified as DMDC 01, entitled ``Defense Manpower Data Center Data Base,'' last published in the Federal...

COMPUTATIONAL TOXICOLOGY: FRAMEWORK, PARTNERSHIPS, AND PROGRAM DEVELOPMENT. SEPTEMBER 29-30, 2003, RESEARCH TRIANGLE PARK, NORTH CAROLINA

EPA Science Inventory

Abstract

The EPA sponsored a workshop held September 29-30, 2003 at the EPA in RTP that was focused on a proposal entitled "A Framework for a Computational Toxicology Research Program in ORD" (www.epa.gov/computox). Computational toxicology is a new research ini...

Electrical stimulation of the brain and the development of cortical visual prostheses: An historical perspective.

PubMed

Lewis, Philip M; Rosenfeld, Jeffrey V

2016-01-01

Rapid advances are occurring in neural engineering, bionics and the brain-computer interface. These milestones have been underpinned by staggering advances in micro-electronics, computing, and wireless technology in the last three decades. Several cortically-based visual prosthetic devices are currently being developed, but pioneering advances with early implants were achieved by Brindley followed by Dobelle in the 1960s and 1970s. We have reviewed these discoveries within the historical context of the medical uses of electricity including attempts to cure blindness, the discovery of the visual cortex, and opportunities for cortex stimulation experiments during neurosurgery. Further advances were made possible with improvements in electrode design, greater understanding of cortical electrophysiology and miniaturisation of electronic components. Human trials of a new generation of prototype cortical visual prostheses for the blind are imminent. This article is part of a Special Issue entitled Hold Item. Copyright © 2015 The Authors. Published by Elsevier B.V. All rights reserved.

Programming Equity into Computer Education: Today's Guide to the Schools of the Future. A PEER Computer Equity Action Kit.

ERIC Educational Resources Information Center

Martin-McCormick, Lynda; And Others

An advocacy packet on educational equity in computer education consists of five separate materials. A booklet entitled "Today's Guide to the Schools of the Future" contains four sections. The first section, a computer equity assessment guide, includes interview questions about school policies and allocation of resources, student and teacher…

[Luís Gomes Ferreira reports on the health of slaves in his work entitled Erário mineral (1735)].

PubMed

Eugênio, Alisson

2015-01-01

The article analyzes the reports of Luís Gomes Ferreira published in his manual on practical medicine entitled Erário mineral, of 1735, on the most common illnesses in captivity. It is shown that such reports can be interpreted as a criticism of the social relations of the slave era by issuing some warnings to the landowners who failed to look after the health of their slaves.

14 CFR 147.5 - Application and issue.

Code of Federal Regulations, 2010 CFR

2010-01-01

... OTHER CERTIFICATED AGENCIES AVIATION MAINTENANCE TECHNICIAN SCHOOLS General § 147.5 Application and... the requirements of this part is entitled to an aviation maintenance technician school certificate and...

Antiterrorist Software

NASA Technical Reports Server (NTRS)

Clark, David A.

1998-01-01

In light of the escalation of terrorism, the Department of Defense spearheaded the development of new antiterrorist software for all Government agencies by issuing a Broad Agency Announcement to solicit proposals. This Government-wide competition resulted in a team that includes NASA Lewis Research Center's Computer Services Division, who will develop the graphical user interface (GUI) and test it in their usability lab. The team launched a program entitled Joint Sphere of Security (JSOS), crafted a design architecture (see the following figure), and is testing the interface. This software system has a state-ofthe- art, object-oriented architecture, with a main kernel composed of the Dynamic Information Architecture System (DIAS) developed by Argonne National Laboratory. DIAS will be used as the software "breadboard" for assembling the components of explosions, such as blast and collapse simulations.

38 CFR 3.260 - Computation of income.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Pension, Compensation, and Dependency and Indemnity Compensation Dependency, Income and Estate § 3.260 Computation of income. For entitlement to pension or dependency and indemnity compensation, income will be... is doubt as to the amount of the anticipated income, pension or dependency and indemnity compensation...

38 CFR 3.260 - Computation of income.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Pension, Compensation, and Dependency and Indemnity Compensation Dependency, Income and Estate § 3.260 Computation of income. For entitlement to pension or dependency and indemnity compensation, income will be... is doubt as to the amount of the anticipated income, pension or dependency and indemnity compensation...

38 CFR 3.260 - Computation of income.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Pension, Compensation, and Dependency and Indemnity Compensation Dependency, Income and Estate § 3.260 Computation of income. For entitlement to pension or dependency and indemnity compensation, income will be... is doubt as to the amount of the anticipated income, pension or dependency and indemnity compensation...

38 CFR 3.260 - Computation of income.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Pension, Compensation, and Dependency and Indemnity Compensation Dependency, Income and Estate § 3.260 Computation of income. For entitlement to pension or dependency and indemnity compensation, income will be... is doubt as to the amount of the anticipated income, pension or dependency and indemnity compensation...

38 CFR 3.260 - Computation of income.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Pension, Compensation, and Dependency and Indemnity Compensation Dependency, Income and Estate § 3.260 Computation of income. For entitlement to pension or dependency and indemnity compensation, income will be... is doubt as to the amount of the anticipated income, pension or dependency and indemnity compensation...

Integrating Multimedia Techniques into CS Pedagogy.

ERIC Educational Resources Information Center

Adams, Sandra Honda; Jou, Richard; Nasri, Ahmad; Radimsky, Anne-Louise; Sy, Bon K.

Through its grants, the National Science Foundation sponsors workshops that inform faculty of current topics in computer science. Such a workshop, entitled, "Developing Multimedia-based Interactive Laboratory Modules for Computer Science," was given July 27-August 6, 1998, at Illinois State University at Normal. Each participant was…

20 CFR 229.43 - When a divorced spouse can no longer be included in computing an annuity under the overall minimum.

Code of Federal Regulations, 2010 CFR

2010-04-01

... included in computing an annuity under the overall minimum. A divorced spouse's inclusion in the... spouse becomes entitled to a retirement or disability benefit under the Social Security Act based upon a...

Company Directory

ERIC Educational Resources Information Center

Environmental Science and Technology, 1972

1972-01-01

Alphabetical listing of manufacturers and suppliers of the products and services listed in this issue of Environmental Science and Technology entitled Pollution Control Directory, 1972-73.'' Information relative to pollution control and abatement. (LK)

User Acceptance Of Commercial Vehicle Operations (CVO) Services, Critical Issues Relating To Acceptance Of CVO Services By Interstate Truck And Bus Drivers, Final Report, Task B Report

DOT National Transportation Integrated Search

1995-08-08

PENN + SCHOEN ASSOCIATES HAS BEEN COMMISSIONED BY THE FEDERAL HIGHWAY ADMINISTRATION TO CONDUCT A STUDY ENTITLED "USER ACCEPTANCE OF COMMERCIAL VEHICLE OPERATIONS (CVO) SERVICES." THE PURPOSE OF THIS STUDY IS TO IDENTIFY AND EVALUATE CRITICAL ISSUES ...

Key Issues in Sex Education: Reflecting on Teaching, Learning and Assessment

ERIC Educational Resources Information Center

Oerton, Sarah; Bowen, Helen

2014-01-01

Drawing upon critical reflections of staff and student experiences of teaching, learning and assessment on an undergraduate module entitled Key Issues in Sex Education, we discuss the strategies used to engage students in debates around sex and relationships education (SRE). To date, there is little research which evaluates how formal assessments…

31 CFR 360.35 - Payment (redemption).

Code of Federal Regulations, 2013 CFR

2013-07-01

... earlier, will be paid at any time after six months from issue date. A Series I bond issued on February 1... STATES SAVINGS BONDS, SERIES I General Provisions for Payment § 360.35 Payment (redemption). (a) General. Payment of a Series I savings bond will be made to the person or persons entitled under the provisions of...

31 CFR 360.35 - Payment (redemption).

Code of Federal Regulations, 2010 CFR

2010-07-01

... earlier, will be paid at any time after six months from issue date. A Series I bond issued on February 1... STATES SAVINGS BONDS, SERIES I General Provisions for Payment § 360.35 Payment (redemption). (a) General. Payment of a Series I savings bond will be made to the person or persons entitled under the provisions of...

31 CFR 360.35 - Payment (redemption).

Code of Federal Regulations, 2011 CFR

2011-07-01

... earlier, will be paid at any time after six months from issue date. A Series I bond issued on February 1... STATES SAVINGS BONDS, SERIES I General Provisions for Payment § 360.35 Payment (redemption). (a) General. Payment of a Series I savings bond will be made to the person or persons entitled under the provisions of...

31 CFR 360.35 - Payment (redemption).

Code of Federal Regulations, 2014 CFR

2014-07-01

... earlier, will be paid at any time after six months from issue date. A Series I bond issued on February 1... STATES SAVINGS BONDS, SERIES I General Provisions for Payment § 360.35 Payment (redemption). (a) General. Payment of a Series I savings bond will be made to the person or persons entitled under the provisions of...

31 CFR 360.35 - Payment (redemption).

Code of Federal Regulations, 2012 CFR

2012-07-01

... earlier, will be paid at any time after six months from issue date. A Series I bond issued on February 1... STATES SAVINGS BONDS, SERIES I General Provisions for Payment § 360.35 Payment (redemption). (a) General. Payment of a Series I savings bond will be made to the person or persons entitled under the provisions of...

SPECIAL ISSUE OF THE JOURNAL OF THE AIR & WASTE MANAGEMENT ASSOCIATION ON THE PARTICULATE MATTER SUPERSITES PROGRAM AND RELATED STUDIES

EPA Science Inventory

This article is the preface or editors note to the dedicated issue of the Journal of the Air & Waste Management Association for a selection of scientific papers from the specialty conference entitled, "Particulate Matter Supersites Program and Related Studies," that was...

Perceptual factors that influence use of computer enhanced visual displays

NASA Technical Reports Server (NTRS)

Littman, David; Boehm-Davis, Debbie

1993-01-01

This document is the final report for the NASA/Langley contract entitled 'Perceptual Factors that Influence Use of Computer Enhanced Visual Displays.' The document consists of two parts. The first part contains a discussion of the problem to which the grant was addressed, a brief discussion of work performed under the grant, and several issues suggested for follow-on work. The second part, presented as Appendix I, contains the annual report produced by Dr. Ann Fulop, the Postdoctoral Research Associate who worked on-site in this project. The main focus of this project was to investigate perceptual factors that might affect a pilot's ability to use computer generated information that is projected into the same visual space that contains information about real world objects. For example, computer generated visual information can identify the type of an attacking aircraft, or its likely trajectory. Such computer generated information must not be so bright that it adversely affects a pilot's ability to perceive other potential threats in the same volume of space. Or, perceptual attributes of computer generated and real display components should not contradict each other in ways that lead to problems of accommodation and, thus, distance judgments. The purpose of the research carried out under this contract was to begin to explore the perceptual factors that contribute to effective use of these displays.

78 FR 50419 - Privacy Act of 1974; CMS Computer Match No. 2013-10; HHS Computer Match No. 1310

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-19

... (Pub. L. 111- 148), as amended by the Health Care and Education Reconciliation Act of 2010 (Pub. L. 111... Entitlements Program System of Records Notice, 77 FR 47415 (August 8, 2012). Inclusive Dates of the Match: The...

Entitlement to Sickness Benefits in Sweden: The Social Insurance Officers Experiences

PubMed Central

Söderberg, Elsy; Müssener, Ulrika

2008-01-01

Background: Social insurance offices (SIOs) handle a wide range of complex assessments of the entitlement to sickness benefits for an increasing number of clients on sick leave and consequently, the demands on the SIOs have increased considerably. Aim: To gain deeper knowledge of the problems experienced by the SIOs in their work associated with entitlement to sickness benefits. Method: A descriptive and explorative qualitative approach was used to analyse data from two focus-group interviews, including six participants in each group. Results: The participants discussed different dilemmas in regard to; physicians’ responsibility for issuing sickness certificates, interactions with the insured individuals, disclosure of decisions, communications with medical consultants, documentation of sickness benefit claims, threats in the workplace, as well as their own competence. The SIOs regarded incomplete information on sickness certificates as a main problem, because they frequently had to contact the client and the physicians who issued the certificates in order to obtain further details, leading to delays in the decision-making whether to grant sickness benefits. Conclusions: More knowledge regarding SIOs work is required to improve the methods used in the sickness insurance system and to ensure adequate training of new staff members. PMID:21572827

Biology Teacher and Expert Opinions about Computer Assisted Biology Instruction Materials: A Software Entitled Nucleic Acids and Protein Synthesis

ERIC Educational Resources Information Center

Hasenekoglu, Ismet; Timucin, Melih

2007-01-01

The aim of this study is to collect and evaluate opinions of CAI experts and biology teachers about a high school level Computer Assisted Biology Instruction Material presenting computer-made modelling and simulations. It is a case study. A material covering "Nucleic Acids and Protein Synthesis" topic was developed as the…

P-KIMMO: A Prolog Implementation of the Two Level Model.

ERIC Educational Resources Information Center

Lee, Kang-Hyuk

Implementation of a computer-based model for morphological analysis and synthesis of language, entitled P-KIMMO, is discussed. The model was implemented in Quintus Prolog on a Sun Workstation and exported to a Macintosh computer. This model has two levels of morphophonological representation, lexical and surface levels, associated by…

Web Based Parallel Programming Workshop for Undergraduate Education.

ERIC Educational Resources Information Center

Marcus, Robert L.; Robertson, Douglass

Central State University (Ohio), under a contract with Nichols Research Corporation, has developed a World Wide web based workshop on high performance computing entitled "IBN SP2 Parallel Programming Workshop." The research is part of the DoD (Department of Defense) High Performance Computing Modernization Program. The research…

78 FR 47830 - Privacy Act of 1974; Report of Matching Program

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-06

... of Veterans Affairs. ACTION: Notice of Computer Matching Program. SUMMARY: The Department of Veterans Affairs (VA) provides notice that it intends to conduct a recurring computer matching program matching... necessary information from RRB-26: Payment, Rate, and Entitlement History File, published at 75 FR 43729...

Incorporation of Ethical and Societal Issues in Biochemistry into a Senior Seminar Course

ERIC Educational Resources Information Center

Caspers, Mary Lou; Roberts-Kirchhoff, Elizabeth S.

2003-01-01

In their senior year, biochemistry majors at the University of Detroit Mercy take a senior seminar course entitled "Recent Advances in Biochemistry Related to Societal Issues." Students read papers selected from the current literature and take turns presenting these papers to the class. Papers are grouped into units dealing with molecular biology,…

Cloud Computing and Its Applications in GIS

NASA Astrophysics Data System (ADS)

Kang, Cao

2011-12-01

Cloud computing is a novel computing paradigm that offers highly scalable and highly available distributed computing services. The objectives of this research are to: 1. analyze and understand cloud computing and its potential for GIS; 2. discover the feasibilities of migrating truly spatial GIS algorithms to distributed computing infrastructures; 3. explore a solution to host and serve large volumes of raster GIS data efficiently and speedily. These objectives thus form the basis for three professional articles. The first article is entitled "Cloud Computing and Its Applications in GIS". This paper introduces the concept, structure, and features of cloud computing. Features of cloud computing such as scalability, parallelization, and high availability make it a very capable computing paradigm. Unlike High Performance Computing (HPC), cloud computing uses inexpensive commodity computers. The uniform administration systems in cloud computing make it easier to use than GRID computing. Potential advantages of cloud-based GIS systems such as lower barrier to entry are consequently presented. Three cloud-based GIS system architectures are proposed: public cloud- based GIS systems, private cloud-based GIS systems and hybrid cloud-based GIS systems. Public cloud-based GIS systems provide the lowest entry barriers for users among these three architectures, but their advantages are offset by data security and privacy related issues. Private cloud-based GIS systems provide the best data protection, though they have the highest entry barriers. Hybrid cloud-based GIS systems provide a compromise between these extremes. The second article is entitled "A cloud computing algorithm for the calculation of Euclidian distance for raster GIS". Euclidean distance is a truly spatial GIS algorithm. Classical algorithms such as the pushbroom and growth ring techniques require computational propagation through the entire raster image, which makes it incompatible with the distributed nature of cloud computing. This paper presents a parallel Euclidean distance algorithm that works seamlessly with the distributed nature of cloud computing infrastructures. The mechanism of this algorithm is to subdivide a raster image into sub-images and wrap them with a one pixel deep edge layer of individually computed distance information. Each sub-image is then processed by a separate node, after which the resulting sub-images are reassembled into the final output. It is shown that while any rectangular sub-image shape can be used, those approximating squares are computationally optimal. This study also serves as a demonstration of this subdivide and layer-wrap strategy, which would enable the migration of many truly spatial GIS algorithms to cloud computing infrastructures. However, this research also indicates that certain spatial GIS algorithms such as cost distance cannot be migrated by adopting this mechanism, which presents significant challenges for the development of cloud-based GIS systems. The third article is entitled "A Distributed Storage Schema for Cloud Computing based Raster GIS Systems". This paper proposes a NoSQL Database Management System (NDDBMS) based raster GIS data storage schema. NDDBMS has good scalability and is able to use distributed commodity computers, which make it superior to Relational Database Management Systems (RDBMS) in a cloud computing environment. In order to provide optimized data service performance, the proposed storage schema analyzes the nature of commonly used raster GIS data sets. It discriminates two categories of commonly used data sets, and then designs corresponding data storage models for both categories. As a result, the proposed storage schema is capable of hosting and serving enormous volumes of raster GIS data speedily and efficiently on cloud computing infrastructures. In addition, the scheme also takes advantage of the data compression characteristics of Quadtrees, thus promoting efficient data storage. Through this assessment of cloud computing technology, the exploration of the challenges and solutions to the migration of GIS algorithms to cloud computing infrastructures, and the examination of strategies for serving large amounts of GIS data in a cloud computing infrastructure, this dissertation lends support to the feasibility of building a cloud-based GIS system. However, there are still challenges that need to be addressed before a full-scale functional cloud-based GIS system can be successfully implemented. (Abstract shortened by UMI.)

Science and technology review, July/August 1997

DOE Office of Scientific and Technical Information (OSTI.GOV)

Upadhye, R.

This month`s issues are entitled Assuring the Safety of Nuclear Power; The Microtechnology Center, When Smaller is Better; Speeding the Gene Hunt: High Speed DNA Sequencing; and Microbial Treatments of High Explosives.

77 FR 47820 - Mid-Atlantic Fishery Management Council (MAFMC); Public Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-10

... Science, will hold a workshop entitled ``Modeling Protogynous Hermaphrodite Fishes.'' DATES: The workshop... discuss data needs and modeling strategies. Although non-emergency issues not contained in this agenda may...

Address By Frances "Sissy" Farenthold

ERIC Educational Resources Information Center

Farenthold, Frances

1978-01-01

Discusses the need for child advocates in the schools and the issues presented in two books entitled "The Plug-In Drug" and "All Our Children". Presented at the IAPPW Convention, Houston, Texas, 1977. (Author/HLM)

75 FR 42431 - Notice of Intent To Grant Partially Exclusive License; METOCEAN Data System

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-21

... exclusive license, with exclusive fields of use in portable acoustic scoring, acoustic sounding and..., issued February 7, 2006, entitled ``Integrated Maritime Portable Acoustic Scoring and Simulator Control...

Corrigendum to ;On the computation of the multidimensional Mittag-Leffler function; [Commun. Nonlinear Sci. Numer. Simulat. 53 (2017) 278-287

NASA Astrophysics Data System (ADS)

Ortigueira, Manuel D.; Lopes, António M.; Machado, J. A. Tenreiro

2018-02-01

In the paper entitled "On the computation of the multidimensional Mittag-Leffler function" there is an error that originates some misleading nomenclature and results. The phrase in Section 2, page 2, three lines after equation (4), should be written as follows:

Letter to the Editor: Use of Publicly Available Image Resources

DOE PAGES

Armato, Samuel G.; Drukker, Karen; Li, Feng; ...

2017-05-11

Here we write with regard to the Academic Radiology article entitled, “Computer-aided Diagnosis for Lung Cancer: Usefulness of Nodule Heterogeneity” by Drs. Nishio and Nagashima (1). The authors also report on a computerized method to classify as benign or malignant lung nodules present in computed tomography (CT) scans.

Clinical Problem Solving: The Case of John, Part II--Excerpts from Sessions 2-7

ERIC Educational Resources Information Center

Drell, Martin J.; Josephson, Allan; Pleak, Richard; Riggs, Paula; Rosenfeld, Alvin

2006-01-01

This article is part two of the three part series of articles entitled "Clinical Problem Solving: The Case of John," with excerpts from Sessions 2-7. In this article, the authors give their responses to sessions 2-7. One author talks about psychodynamic issues and developmental issues, as well as family interaction and intrapsychic problems in…

Coming to Justice: A Program for Youth around Issues of International Justice

ERIC Educational Resources Information Center

van Driel, Barry

2005-01-01

In this article I describe the origins, aims and content of a program developed by the Anne Frank House around issues of international justice. The program, designed for high school and university students who are 17-years-old and older, and entitled "Coming to Justice", takes the betrayal of Jews during the Holocaust as its starting…

Leveraging Emerging Technology to Maintain Corporate Situational Awareness

DTIC Science & Technology

2008-06-01

Abstract and Outline for 13th ICCRTS For the paper entitled: Leveraging Emerging Technology to Maintain Corporate ...Situational Awareness Topics: Topic 5. Organizational Issues Topic 4. Cognitive and Social Issues Topic: 2 Networks and Networking Mr. José...for the collection of information is estimated to average 1 hour per response , including the time for reviewing instructions, searching existing data

Transition from 'model-based' to 'model-free' behavioral control in addiction: Involvement of the orbitofrontal cortex and dorsolateral striatum.

PubMed

Lucantonio, Federica; Caprioli, Daniele; Schoenbaum, Geoffrey

2014-01-01

Cocaine addiction is a complex and multidimensional process involving a number of behavioral and neural forms of plasticity. The behavioral transition from voluntary drug use to compulsive drug taking may be explained at the neural level by drug-induced changes in function or interaction between a flexible planning system, associated with prefrontal cortical regions, and a rigid habit system, associated with the striatum. The dichotomy between these two systems is operationalized in computational theory by positing model-based and model-free learning mechanisms, the former relying on an "internal model" of the environment and the latter on pre-computed or cached values to control behavior. In this review, we will suggest that model-free and model-based learning mechanisms appear to be differentially affected, at least in the case of psychostimulants such as cocaine, with the former being enhanced while the latter are disrupted. As a result, the behavior of long-term drug users becomes less flexible and responsive to the desirability of expected outcomes and more habitual, based on the long history of reinforcement. To support our specific proposal, we will review recent neural and behavioral evidence on the effect of psychostimulant exposure on orbitofrontal and dorsolateral striatum structure and function. This article is part of a Special Issue entitled 'NIDA 40th Anniversary Issue'. Published by Elsevier Ltd.

Evolutionary Theory under Fire.

ERIC Educational Resources Information Center

Lewin, Roger

1980-01-01

Summarizes events of a conference on evolutionary biology in Chicago entitled: "Macroevolution." Reviews the theory of modern synthesis, a term used to explain Darwinism in terms of population biology and genetics. Issues presented at the conference are discussed in detail. (CS)

Intelligent cruise control field operational test : interim report

DOT National Transportation Integrated Search

1997-03-01

This interim document reports on a cooperative agreement between NHTSA and UMTRI entitled Intelligent Cruise Control (ICC) Field Operational Test (FOT). The overarching goal of the work is to characterize safety and comfort issues that are fundamenta...

Cross-cultural invariance of NPI-13: Entitlement as culturally specific, leadership and grandiosity as culturally universal.

PubMed

Żemojtel-Piotrowska, Magdalena; Piotrowski, Jarosław; Rogoza, Radosław; Baran, Tomasz; Hitokoto, Hidefumi; Maltby, John

2018-04-15

The current study explores the problem with the lack of measurement invariance for the Narcissistic Personality Inventory (NPI) by addressing two issues: conceptual heterogeneity of narcissism and methodological issues related to the binary character of data. We examine the measurement invariance of the 13-item version of the NPI in three populations in Japan, Poland and the UK. Analyses revealed that leadership/authority and grandiose exhibitionism dimensions of the NPI were cross-culturally invariant, while entitlement/exploitativeness was culturally specific. Therefore, we proposed NPI-9 as indicating scalar invariance, and we examined the pattern of correlations between NPI-9 and other variables across three countries. The results suggest that NPI-9 is valid brief scale measuring general levels of narcissism in cross-cultural studies, while the NPI-13 remains suitable for research within specific countries. © 2018 International Union of Psychological Science.

20 CFR 229.42 - When a child can no longer be included in computing an annuity rate under the overall minimum.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 20 Employees' Benefits 1 2012-04-01 2012-04-01 false When a child can no longer be included in... Entitlement Under the Overall Minimum Ends § 229.42 When a child can no longer be included in computing an annuity rate under the overall minimum. A child's inclusion in the computation of the overall minimum rate...

20 CFR 229.42 - When a child can no longer be included in computing an annuity rate under the overall minimum.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 20 Employees' Benefits 1 2011-04-01 2011-04-01 false When a child can no longer be included in... Entitlement Under the Overall Minimum Ends § 229.42 When a child can no longer be included in computing an annuity rate under the overall minimum. A child's inclusion in the computation of the overall minimum rate...

20 CFR 229.42 - When a child can no longer be included in computing an annuity rate under the overall minimum.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 20 Employees' Benefits 1 2013-04-01 2012-04-01 true When a child can no longer be included in... Entitlement Under the Overall Minimum Ends § 229.42 When a child can no longer be included in computing an annuity rate under the overall minimum. A child's inclusion in the computation of the overall minimum rate...

20 CFR 229.42 - When a child can no longer be included in computing an annuity rate under the overall minimum.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 20 Employees' Benefits 1 2014-04-01 2012-04-01 true When a child can no longer be included in... Entitlement Under the Overall Minimum Ends § 229.42 When a child can no longer be included in computing an annuity rate under the overall minimum. A child's inclusion in the computation of the overall minimum rate...

Requirements for company-wide management

NASA Technical Reports Server (NTRS)

Southall, J. W.

1980-01-01

Computing system requirements were developed for company-wide management of information and computer programs in an engineering data processing environment. The requirements are essential to the successful implementation of a computer-based engineering data management system; they exceed the capabilities provided by the commercially available data base management systems. These requirements were derived from a study entitled The Design Process, which was prepared by design engineers experienced in development of aerospace products.

The GABA system in schizophrenia: cells, molecules and microcircuitry.

PubMed

Benes, Francine M

2015-09-01

This is an overview of several papers that have been published in the Special Issue of Schizophrenia Research entitled The GABA System in Schizophrenia: Cells, Molecules and Microcircuitry. This issue presents a broad range of original reports and scholarly reviews regarding recent progress in studies of neural circuitry in corticolimbic brain regions in patients with schizophrenia. Copyright © 2015 Elsevier B.V. All rights reserved.

The Quest for Equity in Higher Education: Toward New Paradigms in an Evolving Affirmative Action Era. SUNY Series, Frontiers in Education.

ERIC Educational Resources Information Center

Lindsay, Beverly, Ed.; Justiz, Manuel J., Ed.

This book examines issues of the role of equity, diversity, and affirmative action in colleges and universities in the United States in light of public debates and policy changes. Part 1, entitled Setting the Stage, contains "The Landscape for Conceptual and Policy Issues" (Beverly Lindsay and Manuel J. Justiz). Part 2, Legal and…

Transforming an Introductory Programming Course: From Lectures to Active Learning via Wireless Laptops

ERIC Educational Resources Information Center

Barak, Miri; Harward, Judson; Kocur, George; Lerman, Steven

2007-01-01

Within the framework of MIT's course 1.00: Introduction to Computers and Engineering Problem Solving, this paper describes an innovative project entitled: "Studio 1.00" that integrates lectures with in-class demonstrations, active learning sessions, and on-task feedback, through the use of wireless laptop computers. This paper also describes a…

Un projet de logiciels d'assistance a l'apprentissage de la lecture en FLE (An Interdisciplinary Research Project Oriented toward Computer Programs for Reading Instruction in French as a Second Language).

ERIC Educational Resources Information Center

Challe, Odile; And Others

1985-01-01

Describes a French project entitled "Lecticiel," jointly undertaken by specialists in reading, computer programing, and second language instruction to integrate these disciplines and provide assistance for students learning to read French as a foreign language. (MSE)

Handicapped.

ERIC Educational Resources Information Center

Osborne, Allan G., Jr.

Litigation over the rights of handicapped students and employees continued at a significant level during 1989. Recovery of attorneys' fees was the most frequently litigated handicapped issue. Cases are summarized under the following topics: (1) entitlement to services; (2) procedural safeguards, including change in placement, administrative…

ARL: A Bimonthly Report on Research Library Issues and Actions from ARL, CNI, and SPARC. Special Issue on the Role of the Library in a Digital Landscape, Number 243

ERIC Educational Resources Information Center

Bowen, William G.; Barrett, G. Jaia, Ed.

2005-01-01

This special issue of "ARL: A Bimonthly Report" contains the remarks that William G. Bowen delivered to the research library community in October 2005 at the 147th Membership Meeting of ARL. For the past 17 years Dr. Bowen has served as President of The Andrew W. Mellon Foundation. In these remarks, entitled "New Times Always; Old Time We Cannot…

Special Issue: "Functional Dendrimers".

PubMed

Tomalia, Donald A

2016-08-09

This special issue entitled "Functional Dendrimers" focuses on the manipulation of at least six "critical nanoscale design parameters" (CNDPs) of dendrimers including: size, shape, surface chemistry, flexibility/rigidity, architecture and elemental composition. These CNDPs collectively define properties of all "functional dendrimers". This special issue contains many interesting examples describing the manipulation of certain dendrimer CNDPs to create new emerging properties and, in some cases, predictive nanoperiodic property patterns (i.e., dendritic effects). The systematic engineering of CNDPs provides a valuable strategy for optimizing functional dendrimer properties for use in specific applications.

Permeating disciplines: Overcoming barriers between molecular simulations and classical structure-function approaches in biological ion transport.

PubMed

Howard, Rebecca J; Carnevale, Vincenzo; Delemotte, Lucie; Hellmich, Ute A; Rothberg, Brad S

2018-04-01

Ion translocation across biological barriers is a fundamental requirement for life. In many cases, controlling this process-for example with neuroactive drugs-demands an understanding of rapid and reversible structural changes in membrane-embedded proteins, including ion channels and transporters. Classical approaches to electrophysiology and structural biology have provided valuable insights into several such proteins over macroscopic, often discontinuous scales of space and time. Integrating these observations into meaningful mechanistic models now relies increasingly on computational methods, particularly molecular dynamics simulations, while surfacing important challenges in data management and conceptual alignment. Here, we seek to provide contemporary context, concrete examples, and a look to the future for bridging disciplinary gaps in biological ion transport. This article is part of a Special Issue entitled: Beyond the Structure-Function Horizon of Membrane Proteins edited by Ute Hellmich, Rupak Doshi and Benjamin McIlwain. Copyright © 2017 Elsevier B.V. All rights reserved.

New trends in species distribution modelling

USGS Publications Warehouse

Zimmermann, Niklaus E.; Edwards, Thomas C.; Graham, Catherine H.; Pearman, Peter B.; Svenning, Jens-Christian

2010-01-01

Species distribution modelling has its origin in the late 1970s when computing capacity was limited. Early work in the field concentrated mostly on the development of methods to model effectively the shape of a species' response to environmental gradients (Austin 1987, Austin et al. 1990). The methodology and its framework were summarized in reviews 10–15 yr ago (Franklin 1995, Guisan and Zimmermann 2000), and these syntheses are still widely used as reference landmarks in the current distribution modelling literature. However, enormous advancements have occurred over the last decade, with hundreds – if not thousands – of publications on species distribution model (SDM) methodologies and their application to a broad set of conservation, ecological and evolutionary questions. With this special issue, originating from the third of a set of specialized SDM workshops (2008 Riederalp) entitled 'The Utility of Species Distribution Models as Tools for Conservation Ecology', we reflect on current trends and the progress achieved over the last decade.

Intelligent cruise control field operational test. Volume I, Technical report

DOT National Transportation Integrated Search

1998-05-01

This document reports on a cooperative agreement between NHTSA and UMTRI entitled Intelligent Cruise Control (ICC) Field Operational Test (FOT). The main goal of the work is to characterize safety and comfort issues that are fundamental to human inte...

78 FR 48516 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Notice of Filing and Immediate Effectiveness...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-08

... Rotations, Halts and Suspensions'' and Rule 1047A, entitled ``Trading Rotations, Halts or Reopenings'' to... trading for technical issues on Phlx. \\3\\ See Rule 1. An ``Option Exchange Official'' is an Exchange staff...

Suggestopaedia-Canada. Information Letter, No. 2.

ERIC Educational Resources Information Center

Racle, Gabriel

This issue consists of the following: an article entitled "Suggestopaedia and Language Teaching, International Perspective"; an article which discusses possible adaptations of the Bulgarian Suggestopaedia - A New Method of Teaching Foreign Languages"; and bibliographical notes from Canada and Bulgaria announcing new publications on…

What Next in Health Policy?

ERIC Educational Resources Information Center

Ginzberg, Eli

1975-01-01

A National Health Insurance (NHI) bill is discussed. Such a law would address primarly two issues: financial coverage for catastrophic illness and some broadening of entitlements for ambulatory care. Current need, financial support, Federal and local planning and priority objectives are reviewed. (Author/EB)

National Forums '89. Citizens, Leaders Look at Our Democracy. A Report on the Conference (Washington, D.C., April 16-19, 1989).

ERIC Educational Resources Information Center

National Issues Forums, Dayton, OH.

This publication presents reports from National Forums '89, the culminating event of the National Issues Forums (NIF) 1988-89 cycle. A brief overview of this event is followed by a summary of the session entitled Executive Branch Conference: Reports from the Forums, in which policymakers were briefed on the outcomes of each of the 1988-89 issues.…

User's manual for the Noise 1 area computer program for transportation noise prediction : report under project entitled "area computer model for transportation noise prediction : phase 1 : adaptation of MICNOISE".

DOT National Transportation Integrated Search

1975-01-01

It was found that the coordinates of the highways required for Noise 1 could be supplied on punched cards by the Photogrammetry Section of the Department. In preparing data for contour plotting, it was found advisable to divide the area into sectors,...

The Role of Subjectivity: Response to Noriyuki Inoue

ERIC Educational Resources Information Center

Walton, Joan

2016-01-01

This paper offers a response to Dr. Noriyuki Inoue's article published in this issue of the "International Journal for Transformative" research, entitled "The Role of Subjectivity in Teacher Expertise Development: Mindfully Embracing the 'Black Sheep' of Educational Research." Inoue freely uses the terms…

Responses to Horner and Carr.

ERIC Educational Resources Information Center

Durand, V. Mark; And Others

1997-01-01

Five special educators (Durand, Bambara, Dunlap, Kennedy, and Wacker) respond to an article in the same issue by Horner and Carr entitled "Behavioral Support for Students with Severe Disabilities: Functional Assessment and Comprehensive Intervention." Respondents raise concerns regarding the range of intervention options, the behavioral…

EST! environmentally sustainable transport issue paper : soft measures and transport

DOT National Transportation Integrated Search

2002-12-01

The purpose of this paper was to help guide and even provoke discussion at the workshop to be held in Berlin on 5-6 December, 2002, entitled Communicating Environmentally Sustainable Transport-The roles of soft measures in achieving EST. It's easier ...

Promoting Civic Literacy.

ERIC Educational Resources Information Center

Brown, Peggy Ann, Ed.

1985-01-01

Descriptions of college programs that integrate civic issues and responsibilities are provided, along with an essay entitled "Liberal Education's Civic Agenda," by Arthur Levine and David Haselkorn. The essay recommends a curriculum that emphasizes such things as basic skills and problem solving, and values and ethics. The program…

Code of conduct for the International Space Station Crew. National Aeronautics and Space Administration (NASA). Interim final rule.

PubMed

2000-12-21

NASA is issuing new regulations entitled "International Space Station Crew," to implement certain provisions of the International Space Station (ISS) Intergovernmental Agreement (IGA) regarding ISS crewmembers' observance of an ISS Code of Conduct.

78 FR 69927 - Notice to Manufacturers of Continuous Friction Measurement Equipment (CFME)

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-21

... Friction Measurement Equipment (CFME) AGENCY: Federal Aviation Administration (FAA), US DOT. ACTION: Notice... (FAA) is considering issuing waivers to foreign manufacturers of Continuous Friction Measurement... entitled, Continuous Friction Measurement Equipment Request for Qualifications. The FAA wants to determine...

Intelligent cruise control field operational test. Vol II, Appendices A-F

DOT National Transportation Integrated Search

1998-05-01

This document reports on a cooperative agreement between NHTSA and UMTRI entitled Intelligent Cruise Control (ICC) Field Operational Test (FOT). The main goal of the work is to characterize safety and comfort issues that are fundamental to human inte...

Ethics and the 7 `P`s` of computer use policies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Scott, T.J.; Voss, R.B.

1994-12-31

A Computer Use Policy (CUP) defines who can use the computer facilities for what. The CUP is the institution`s official position on the ethical use of computer facilities. The authors believe that writing a CUP provides an ideal platform to develop a group ethic for computer users. In prior research, the authors have developed a seven phase model for writing CUPs, entitled the 7 P`s of Computer Use Policies. The purpose of this paper is to present the model and discuss how the 7 P`s can be used to identify and communicate a group ethic for the institution`s computer users.

From head to tail: new models and approaches in primate functional anatomy and biomechanics.

PubMed

Organ, Jason M; Deleon, Valerie B; Wang, Qian; Smith, Timothy D

2010-04-01

This special issue of The Anatomical Record (AR) is based on interest generated by a symposium at the 2008 annual meeting of the American Association of Anatomists (AAA) at Experimental Biology, entitled "An Evolutionary Perspective on Human Anatomy." The development of this volume in turn provided impetus for a Biological Anthropology Mini-Meeting, organized by members of the AAA for the 2010 Experimental Biology meeting in Anaheim, California. The research presented in these pages reflects the themes of these symposia and provides a snapshot of the current state of primate functional anatomy and biomechanics research. The 17 articles in this special issue utilize new models and/or approaches to study long-standing questions about the evolution of our closest relatives, including soft-tissue dissection and microanatomical techniques, experimental approaches to morphology, kinematic and kinetic biomechanics, high-resolution computed tomography, and Finite Element Analysis (FEA). This volume continues a close historical association between the disciplines of anatomy and biological anthropology: anatomists benefit from an understanding of the evolutionary history of our modern form, and biological anthropologists rely on anatomical principles to make informed evolutionary inferences about our closest relatives. (c) 2010 Wiley-Liss, Inc.

[Comment on “Open scientific communication urged” “Technology transfer-A growing problem” and “Update: Science and security”] DOD funds

NASA Astrophysics Data System (ADS)

Walder, Joseph

The most significant observation to be made about the recent (Oct. 5, 12, and 19) news items in Eos on ‘technology transfer’ is that several key issues were never even addressed. For example, actual or potential censorship of technical papers is reported to have caused ‘considerable clamor within the scientific community,’ yet never once were directly relevant questions asked. For example: Should academic researchers depend upon military funding for their support? Does acceptance of financial support from military sources make individuals and institutions dependent clients of the Pentagon? In this context it is ironic to note that the Oct. 12 issue of Eos also featured an article entitled ‘DOD to Fund Major Instruments,’ describing the manner in which DOD intends to spend $150 million to equip university laboratories in the next 5 years. This article noted explicitly that ‘For example, computers obtained with the program funds are to be used only for defense-related projects’ (my emphasis). It seems that scientists should reflect a bit about a funding system that channels dollars through the military.

Two Studies on the Role of Business & Industry and Labor Participation in Career Education: Enhancing Business and Industry Participation in Career Education; Issues and Strategies for Enhancing the Participation of Labor in the Implementation of Career Education.

ERIC Educational Resources Information Center

Hensley, Gene; Schulman, Mark

The first paper contained in this document, entitled "Enhancing Business and Industry Participation in Career Education," addresses the following topics: Interrelationships between business, industry and schools, issues in strengthening the collaboration of education and business and industry, problems and possibilities of increased interaction,…

Comments on Professor Lortie's Paper Entitled "The Cracked Cake of Educational Custom and Emerging Issues in Evaluation." Center for the Study of Evaluation of Instructional Programs Occasional Report No. 21.

ERIC Educational Resources Information Center

Gage, N. L.

This commentary takes no serious exception to Professor Lortie's conclusions about educational changes and issues in evaluation, but it examines certain assumptions. It questions the implications that each school district needs independent evaluation and that evaluation should be applied at the end of a given educational program, and asks what…

25 CFR 249.3 - Identification cards.

Code of Federal Regulations, 2011 CFR

2011-04-01

... OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FISH AND WILDLIFE OFF-RESERVATION TREATY FISHING... evidence that the authorized holder thereof is entitled to exercise the fishing rights secured by the... exercise of any tribal fishing right. (f) All cards issued by the Commisssioner of Indian Affairs pursuant...

25 CFR 249.3 - Identification cards.

Code of Federal Regulations, 2010 CFR

2010-04-01

... OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FISH AND WILDLIFE OFF-RESERVATION TREATY FISHING... evidence that the authorized holder thereof is entitled to exercise the fishing rights secured by the... exercise of any tribal fishing right. (f) All cards issued by the Commisssioner of Indian Affairs pursuant...

The "Scholar's Anthology": Televisual Studies.

ERIC Educational Resources Information Center

Gronbeck, Bruce E., Ed.

1983-01-01

The five major articles in this journal issue focus on television criticism as an academic field. An introduction, entitled "The 'Scholar's Anthology': Televisual Studies" (Bruce Gronbeck), is followed by articles discussing the following topics: (1) the discourses of television quiz programs (John Fiske), (2) the dialectic of feminine…

Opening Transportation Data for the Public Good : Getting Our Bits in a Row

DOT National Transportation Integrated Search

2016-09-01

The U.S. Department of Transportation (USDOT) Public Access Plan was issued in November 2015, in response to the February 22, 2013 Office of Science and Technology Policy (OSTP) Memorandum for the Heads of Executive Departments and Agencies entitled ...

Explorations in Regional Variation: A Variational Pragmatic Perspective

ERIC Educational Resources Information Center

Barron, Anne

2015-01-01

The present article introduces the Special Issue entitled "A Variational Pragmatic Approach to Regional Variation in Language," a collection of papers which celebrates the work of Klaus P. Schneider (Rheinische Friedrich-Wilhelms-Universität Bonn, Germany) on the occasion of his 60th birthday.

Plan to increase public access to the results of Federally-funded scientific research results.

DOT National Transportation Integrated Search

2015-12-16

This plan is issued in response to the February 22, 2013 Office of Science and Technology Policy (OSTP) Memorandum for the Heads of Executive Departments and Agencies entitled Increasing Access to the Results of Federally Funded Scientific Researc...

76 FR 6456 - Intent To Grant an Exclusive License for a U.S. Government-Owned Invention

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-04

..., revocable license, to U.S. Patent No. 6,254,873, issued July 3, 2001, entitled ``Inactivated Dengue Virus... against Dengue virus for human use. The intended licensee is GlaxoSmithKline Bio, with its principal place...

Designing Nordic Technology-Enhanced Learning

ERIC Educational Resources Information Center

Cerratto-Pargman, Teresa; Jarvela, Sanna M.; Milrad, Marcelo

2012-01-01

The latest developments of information and communication technologies (ICT) and its large penetration in different sectors of our society pose new challenges and demands in the field of education. This special issue entitled "Designing Nordic technology-enhanced learning (TEL)", presents and discusses how researchers in the Nordic…

Education of Native Americans Today.

ERIC Educational Resources Information Center

Triplett, DeWayne R., Ed.; Ellis, Joseph R., Ed.

1978-01-01

Various aspects of Indian education are treated in the two poems and 12 articles that constitute this issue of "Thresholds in Education." An article entitled "Indian Self-Determination and Indian Education" charts the growth of the self-determination movement, the influence of cultural pluralism, and the increasing involvement…

Edutopia, 1993-1995.

ERIC Educational Resources Information Center

Edutopia, 1994

1994-01-01

This document consists of the first four issues of a newsletter entitled "Edutopia." The name Edutopia signifies a version of what a technology-enriched educational system of the future would look like. The newsletter is intended to facilitate the integration of interactive multimedia and telecommunications technologies with teaching and…

Education Facilities for Young Children

ERIC Educational Resources Information Center

Meade, Anne; Ross, Fiona

2006-01-01

Educational buildings and grounds can provide a supportive and stimulating environment for the learning process as well as contribute to greater community needs. These issues were addressed at an international conference entitled "Making Space: Architecture and Design for Young Children". Described here are the importance of outdoor…

On Critchfield's Proposal: Student Concerns and Recommendations

ERIC Educational Resources Information Center

Bayles, Makenzie W.; Boutain, Ariana R.; Brandt, Julie A. Ackerlund; Call, Nikki; Dracobly, Joseph D.; Greer, Brian D.; Gureghian, Danielle L.; Harper, Amy M.; Merritt, Todd A.; Miller, Jonathan R.; Payne, Steven W.; Morris, Edward K.

2012-01-01

An issue of "The Behavior Analyst" contained an article by Critchfield (2011), entitled "Interesting Times: Practice, Science, and Professional Associations in Behavior Analysis," about a rift between the field's scientists and practitioners. Critchfield observed that the science and practice of behavior analysis are subject to different…

Case Study Evaluation of the Boston Area Carpooling Program

DOT National Transportation Integrated Search

1976-05-01

The report evaluates a carpooling program in operation in the Boston, Massachusetts area from August, 1973 through August, 1974. The program, entitled the WBZ/ALA Commuter Computer Campaign, was the first program in the nation to promote and organize...

77 FR 43639 - Privacy Act of 1974, as Amended; Computer Matching Program (Social Security Administration (SSA...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-25

... pension payment data from its system of records (SOR) entitled the ``Compensation, Pension, Education, and... monthly. The actual match will take place approximately during the first week of every month. E. Inclusive...

Image gently, step lightly: increasing radiation dose awareness in pediatric interventions through an international social marketing campaign.

PubMed

Sidhu, Manrita K; Goske, Marilyn J; Coley, Brian J; Connolly, Bairbre; Racadio, John; Yoshizumi, Terry T; Utley, Tara; Strauss, Keith J

2009-09-01

In the past several decades, advances in imaging and interventional techniques have been accompanied by an increase in medical radiation dose to the public. Radiation exposure is even more important in children, who are more sensitive to radiation and have a longer lifespan during which effects may manifest. To address radiation safety in pediatric computed tomography, in 2008 the Alliance for Radiation Safety in Pediatric Imaging launched an international social marketing campaign entitled Image Gently. This article describes the next phase of the Image Gently campaign, entitled Step Lightly, which focuses on radiation safety in pediatric interventional radiology.

Severe Weather

ERIC Educational Resources Information Center

Forde, Evan B.

2004-01-01

Educating the public about safety issues related to severe weather is part of the National Oceanic and Atmospheric Administration's (NOAA) mission. This article deals with a poster entitled, "Severe Weather," that has been created by NOAA to help educate the public about hazardous weather conditions. The four types of severe weather highlighted in…

12 CFR 509.30 - Partial summary disposition.

Code of Federal Regulations, 2010 CFR

2010-01-01

... PROCEDURE IN ADJUDICATORY PROCEEDINGS Uniform Rules of Practice and Procedure § 509.30 Partial summary disposition. If the administrative law judge determines that a party is entitled to summary disposition as to... on the remaining issues must be ordered. Those claims for which the administrative law judge has...

FACCCTS: The Journal of the Faculty Association of California Community Colleges, 1997-1998.

ERIC Educational Resources Information Center

Martinez, Katherine, Ed.

1998-01-01

This document contains the four Faculty Association of California Community Colleges (FACCCTS) newsletters published during the 1997-98 academic year. The first issue, entitled "Realities, Myths, and Perceptions of the California Community Colleges," contains the following articles: "Myth Perceptions,""Budget Brings Great…

45 CFR 672.13 - Accelerated decision; decision to dismiss.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Section 672.13 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE... genuine issue of material fact exists and a party is entitled to judgment as a matter of law regarding all... determine what material facts exist without substantial controversy and what material facts remain...

45 CFR 672.13 - Accelerated decision; decision to dismiss.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Section 672.13 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE... genuine issue of material fact exists and a party is entitled to judgment as a matter of law regarding all... determine what material facts exist without substantial controversy and what material facts remain...

45 CFR 672.13 - Accelerated decision; decision to dismiss.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Section 672.13 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE... genuine issue of material fact exists and a party is entitled to judgment as a matter of law regarding all... determine what material facts exist without substantial controversy and what material facts remain...

45 CFR 672.13 - Accelerated decision; decision to dismiss.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Section 672.13 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE... genuine issue of material fact exists and a party is entitled to judgment as a matter of law regarding all... determine what material facts exist without substantial controversy and what material facts remain...

45 CFR 672.13 - Accelerated decision; decision to dismiss.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Section 672.13 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE... genuine issue of material fact exists and a party is entitled to judgment as a matter of law regarding all... determine what material facts exist without substantial controversy and what material facts remain...

29 CFR 4041.31 - Notice of noncompliance.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Regulations Relating to Labor (Continued) PENSION BENEFIT GUARANTY CORPORATION PLAN TERMINATIONS TERMINATION... § 4041.23; (ii) The plan administrator failed to issue notices of plan benefits to all affected parties entitled to plan benefits in accordance with § 4041.24; (iii) The plan administrator failed to file the...

Toward (Whose) Morality in Teacher Education?

ERIC Educational Resources Information Center

Milner, H. Richard; Delale-O'Connor, Lori

2016-01-01

Richard Milner, and Lori Delale-O'Connor offer their remarks on Daniel Lapsley & Ryan Woodbury's commentary (available in this v38 n3 2016 issue of "Action in Teacher Education") entitled "Moral Character Development for Teacher Education." They begin the conversation by commenting that Lapsley and Woodbury raise some…

Sandcastle Competitions

ERIC Educational Resources Information Center

Baggaley, Jon

2016-01-01

This commentary discusses reasons that lead scholars to feel entitled to make judgements in areas where they have little or no expertise. Three current reports about the future of online learning are considered, issued by the Global Learning Council, Massachusetts Institute of Technology, and the Gates Foundation. Two of these publications contain…

Suggestopaedia-Canada. Information Letter, No. 3.

ERIC Educational Resources Information Center

Racle, Gabriel

This issue consists of the following: a "minilexicon" of terms directly or indirectly related to the field of suggestion and learning; the translation of an article by T. Tachev entitled "Learning Foreign Languages by Suggestion: The Unsuspected Possibilities of Human Memory"; a review of the book "An Introduction to…

Youth Studies Bulletin. Vol. 3 No. 2.

ERIC Educational Resources Information Center

Youth Studies Bulletin, 1984

1984-01-01

This bulletin contains materials--announcements, papers, and studies--that are concerned with youth policy issues and that focus on education and training. The first section, entitled Quidnunc, offers brief descriptions of projects of interest, reports recent appointments, and announces conferences. The second section, called Aspects, offers two…

77 FR 14405 - Preparation for International Cooperation on Cosmetics Regulations; Public Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-09

...] Preparation for International Cooperation on Cosmetics Regulations; Public Meeting AGENCY: Food and Drug... public meeting entitled ``International Cooperation on Cosmetics Regulations (ICCR)-Preparation for ICCR.... Interested persons may present data, information, or views orally or in writing, on issues pending at the...

School Choice: Examining the Evidence.

ERIC Educational Resources Information Center

Rasell, Edith, Ed.; Rothstein, Richard, Ed.

This book presents a summary of school-choice issues, and is organized around a 1992 seminar entitled "Choice: What Role in American Education?" Each part presents a set of conference papers, followed by discussants' remarks and excerpts from audience discussion. The introduction summarizes the papers' positions and conclusions. Participants…

The Process of Designing Task Features

ERIC Educational Resources Information Center

Bauer, Malcolm

2014-01-01

Malcolm Bauer, from Education Testing Services, provides his comments on the Focus article in this issue of "Measurement" entitled : "How Task Features Impact Evidence from Assessments Embedded in Simulations and Games" (Russell G. Almond, Yoon Jeon Kim, Gertrudes Velasquez, Valerie J. Shute). Bauer begins his remarks by noting…

Rational design of liposomal drug delivery systems, a review: Combined experimental and computational studies of lipid membranes, liposomes and their PEGylation.

PubMed

Bunker, Alex; Magarkar, Aniket; Viitala, Tapani

2016-10-01

Combined experimental and computational studies of lipid membranes and liposomes, with the aim to attain mechanistic understanding, result in a synergy that makes possible the rational design of liposomal drug delivery system (LDS) based therapies. The LDS is the leading form of nanoscale drug delivery platform, an avenue in drug research, known as "nanomedicine", that holds the promise to transcend the current paradigm of drug development that has led to diminishing returns. Unfortunately this field of research has, so far, been far more successful in generating publications than new drug therapies. This partly results from the trial and error based methodologies used. We discuss experimental techniques capable of obtaining mechanistic insight into LDS structure and behavior. Insight obtained purely experimentally is, however, limited; computational modeling using molecular dynamics simulation can provide insight not otherwise available. We review computational research, that makes use of the multiscale modeling paradigm, simulating the phospholipid membrane with all atom resolution and the entire liposome with coarse grained models. We discuss in greater detail the computational modeling of liposome PEGylation. Overall, we wish to convey the power that lies in the combined use of experimental and computational methodologies; we hope to provide a roadmap for the rational design of LDS based therapies. Computational modeling is able to provide mechanistic insight that explains the context of experimental results and can also take the lead and inspire new directions for experimental research into LDS development. This article is part of a Special Issue entitled: Biosimulations edited by Ilpo Vattulainen and Tomasz Róg. Copyright © 2016 Elsevier B.V. All rights reserved.

An on-line system for hand-printed input

NASA Technical Reports Server (NTRS)

Williams, T. G.; Bebb, J.

1971-01-01

The capability of graphic input/output systems is described. Topics considered are a character recognizer and dictionary building program, an initial flow chart element input program, and a system entitled The Assistant Mathematician, which uses ordinary mathematics to specify numeric computation. All three parts are necessary to allow a user to carry on a mathematical dialogue with the computer in the language and notation of his discipline or problem domain.

Modeling covalent-modifier drugs.

PubMed

Awoonor-Williams, Ernest; Walsh, Andrew G; Rowley, Christopher N

2017-11-01

In this review, we present a summary of how computer modeling has been used in the development of covalent-modifier drugs. Covalent-modifier drugs bind by forming a chemical bond with their target. This covalent binding can improve the selectivity of the drug for a target with complementary reactivity and result in increased binding affinities due to the strength of the covalent bond formed. In some cases, this results in irreversible inhibition of the target, but some targeted covalent inhibitor (TCI) drugs bind covalently but reversibly. Computer modeling is widely used in drug discovery, but different computational methods must be used to model covalent modifiers because of the chemical bonds formed. Structural and bioinformatic analysis has identified sites of modification that could yield selectivity for a chosen target. Docking methods, which are used to rank binding poses of large sets of inhibitors, have been augmented to support the formation of protein-ligand bonds and are now capable of predicting the binding pose of covalent modifiers accurately. The pK a 's of amino acids can be calculated in order to assess their reactivity towards electrophiles. QM/MM methods have been used to model the reaction mechanisms of covalent modification. The continued development of these tools will allow computation to aid in the development of new covalent-modifier drugs. This article is part of a Special Issue entitled: Biophysics in Canada, edited by Lewis Kay, John Baenziger, Albert Berghuis and Peter Tieleman. Copyright © 2017 Elsevier B.V. All rights reserved.

Software Review.

ERIC Educational Resources Information Center

McGrath, Diane, Ed.

1989-01-01

Reviewed is a computer software package entitled "Audubon Wildlife Adventures: Grizzly Bears" for Apple II and IBM microcomputers. Included are availability, hardware requirements, cost, and a description of the program. The murder-mystery flavor of the program is stressed in this program that focuses on illegal hunting and game…

20 CFR 404.282 - Effective date of recomputations.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Section 404.282 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Computing Primary Insurance Amounts Recomputing Your Primary Insurance Amount... Social Security benefit amount is effective for the first month you are entitled to the pension. Finally...

45 CFR 307.1 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-10-01

... system means the hardware, operational software, applications software and electronic linkages in an... further defined in the OCSE guideline entitled “Automated Systems for Child Support Enforcement: A Guide... training, testing, and conversion plans to install the computer system. (j) The following terms are defined...

45 CFR 307.1 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... system means the hardware, operational software, applications software and electronic linkages in an... further defined in the OCSE guideline entitled “Automated Systems for Child Support Enforcement: A Guide... training, testing, and conversion plans to install the computer system. (j) The following terms are defined...

45 CFR 307.1 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... system means the hardware, operational software, applications software and electronic linkages in an... further defined in the OCSE guideline entitled “Automated Systems for Child Support Enforcement: A Guide... training, testing, and conversion plans to install the computer system. (j) The following terms are defined...

45 CFR 307.1 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-10-01

... system means the hardware, operational software, applications software and electronic linkages in an... further defined in the OCSE guideline entitled “Automated Systems for Child Support Enforcement: A Guide... training, testing, and conversion plans to install the computer system. (j) The following terms are defined...

45 CFR 307.1 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... system means the hardware, operational software, applications software and electronic linkages in an... further defined in the OCSE guideline entitled “Automated Systems for Child Support Enforcement: A Guide... training, testing, and conversion plans to install the computer system. (j) The following terms are defined...

Computer Tree

ERIC Educational Resources Information Center

Agaoglu, Onur

2014-01-01

It is crucial that gifted and talented students should be supported by different educational methods for their interests and skills. The science and arts centres (gifted centres) provide the Supportive Education Program for these students with an interdisciplinary perspective. In line with the program, an ICT lesson entitled "Computer…

Intercultural Dimensions of Teaching Speech Communication in Malaysia: Negotiating the Malays' Malaise.

ERIC Educational Resources Information Center

Dick, Robert C.; Robinson, Brenda M.

A study examined a cooperative international education program established between Indiana University and the government of Malaysia entitled the Institut Teknologi MARA/Midwest University Consortium for International Activities (ITM/MUCIA). It further explored the issues to be addressed in turning over the program to Malaysian faculty and…

12 CFR 308.30 - Partial summary disposition.

Code of Federal Regulations, 2010 CFR

2010-01-01

... PRACTICE AND PROCEDURE Uniform Rules of Practice and Procedure § 308.30 Partial summary disposition. If the administrative law judge determines that a party is entitled to summary disposition as to certain claims only, he... issues must be ordered. Those claims for which the administrative law judge has determined that summary...

Parasitic Weeds, a Scientific Challenge

USDA-ARS?s Scientific Manuscript database

A recent issue of the SCI journal Pest Management Science (May, 2009) was devoted to an overview of the problem of parasitic weeds and to the research that is being done to alleviate it. These papers are from an OECD-sponsored conference entitled Managing Parasitic Weeds that recently brought the b...

Guest Editorial

DOE PAGES

Deline, Christopher A; van Sark, Wilfried; Georghiou, George E.

2017-08-16

This Special Issue entitled 'Performance Assessment and Condition Monitoring of Photovoltaic Systems for Improved Energy Yield', contains ten papers that discuss various aspects in performance assessment, thus bringing the reader up to date with the present state-of-the-art technologies. In particular, the following topics are addressed: system performance monitoring; operational analysis and design; solar forecasting.

48 CFR 305.205 - Special situations.

Code of Federal Regulations, 2010 CFR

2010-10-01

... situations. (a) An OPDIV may issue an advance notice, entitled “Research and Development Sources Sought,” in Federal Business Opportunities (FedBizOpps), in accordance with the requirements of FAR 5.205(a). The... requirement. The notice is not intended to solicit technical, scientific, or business information for project...

76 FR 69284 - Pure Magnesium From China

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-08

... China Determination On the basis of the record \\1\\ developed in the subject five-year review, the United... China would be likely to lead to continuation or recurrence of material injury to an industry in the...), entitled Pure Magnesium from China: Investigation No. 731-TA-696 (Third Review). Issued: November 2, 2011...

Sustainable School Capacity Building--One Step Back, Two Steps Forward?

ERIC Educational Resources Information Center

Dinham, Stephen; Crowther, Frank

2011-01-01

Purpose: This paper aims to serve as an introduction to and overview of this special issue of the "Journal of Educational Administration" entitled "Building organisational capacity in school education". The co-editors have solicited contributions from authors in Wales, Australia, Canada, the USA, England, Hong Kong and New…

Interfaces. Linguistics and Psychoanalysis Newsletter, No. 6.

ERIC Educational Resources Information Center

Di Pietro, Robert, Ed.

This newsletter reports on phenomena at the intersection of linguistics and psychoanalysis and psychiatry. This issue consists of the following articles: (1) an editorial entitled "Idioms, How We Love/Have You!", on the possible reasons behind the use of idioms; (2) "The Last Renaissance (Language in a Drug Rehabilitation Community)," by Harold…

The Industrial Base and National Security: A New Strategy

DTIC Science & Technology

1993-04-01

addresses this issue in her article entitled, " Managing Innovation on the Factory Floor": Manufacturing managers often buy the most advanced...Incentives Program." Government Contract Number MDA903-85-C-0139 Final Report, 1986. 31 11. Tyre, Marcie J. " Managing Innovation On The Factory Floor

Thinking Critically about Social Issues through Visual Material

ERIC Educational Resources Information Center

Rawlinson, Kate; Wood, Susan Nelson; Osterman, Mark; Sullivan, Claudia Caro

2007-01-01

This article addresses an arts-integrated social studies curriculum for grades three through five entitled Artful Citizenship, designed by The Wolfsonian-Florida International University. Funded by the U.S. Department of Education's Arts in Education Model Development and Dissemination Grant program, the design and implementation of the program…

On Campus with Women. Spring 1986 [and] Summer 1986.

ERIC Educational Resources Information Center

On Campus with Women, 1986

1986-01-01

Developments in education, employment, and the courts concerning the status of women are covered in two newsletter issues. Included is an article from "Ms. Magazine" entitled "Do SATs Shortchange Women?" News items include the following: a salary bias court case, minority women in intercollegiate athletics, athletic scholarships for women,…

77 FR 2556 - Ethical and Regulatory Challenges in the Development of Pediatric Medical Countermeasures; Public...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-18

...] Ethical and Regulatory Challenges in the Development of Pediatric Medical Countermeasures; Public Workshop... Administration (FDA), Office of Pediatric Therapeutics, is announcing a public workshop entitled ``Ethical and... provide a forum for careful consideration of scientific, ethical, and regulatory issues confronting FDA...

Building a Legacy: Women in Social Education, 1784-1984. NCSS Bulletin.

ERIC Educational Resources Information Center

Crocco, Margaret Smith, Ed.; Davis, O. L., Jr., Ed.

This collection of biographical articles presents several issues concerning story of women working in the social studies placing it within a broad intellectual and social context. Following the "Preface" (M. S. Crocco), the collection is divided into five chronological sections. The first section entitled, "Conceptualizing Social…

Revisiting the Blind Alley of Value Added

ERIC Educational Resources Information Center

Banta, Trudy W.; Pike, Gary R.

2007-01-01

The Commission on the Future of Higher Education appointed by Secretary of Education Margaret Spellings issued a report in September 2006 entitled "A Test of Leadership: Charting the Future of U.S. Higher Education" [U.S. Department of Education, 2006(ED493504)]. Two key commission recommendations are stated: "Higher education institutions should…

Districts, Local Education Authorities, and the Context of Policy Analysis

ERIC Educational Resources Information Center

Louis, Karen Seashore

2013-01-01

Purpose: The purpose of this paper is to present the author's commentary on the special issue of "Journal of Educational Administration" entitled "Systemwide Reform: Examining Districts under Pressure". Design/methodology/approach: The author gives her personal opinions, draws upon her recent experiences in the national…

75 FR 70725 - Spectrum Policy Seminar for the Utility Sector

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-18

... Wazer, Senior Advisor, Technology Law (202) 586-3421; [email protected] . For Media Inquires you may... comment process, the Department of Energy (DOE) issued a report entitled, ``Communications Requirements of Smart Grid Technologies. '' The complete text of the report, and of a second report addressing data...

Focus on Law Studies, 1990-91.

ERIC Educational Resources Information Center

Focus on Law Studies, 1991

1991-01-01

The fall 1990 issue includes essays that recapture some of the presentations and thinking of the 1990 American Bar Association annual conference on higher education, entitled "American Citizenship and the Constitution." The idea of community was a recurring theme of the conference, and is the focus of three essays included in the Fall…

78 FR 22349 - Guidance on the Treatment of Uncertainties Associated With PRA in Risk-Informed Decisionmaking

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-15

... NUCLEAR REGULATORY COMMISSION [NRC-2012-0066] Guidance on the Treatment of Uncertainties Associated With PRA in Risk-Informed Decisionmaking AGENCY: Nuclear Regulatory Commission. ACTION... issued for public comment a document entitled: NUREG-1855, Revision 1, ``Guidance on the Treatment of...

Riparian ecosystems and buffers - multiscale structure, function, and management: introduction

Treesearch

Kathleen A. Dwire; Richard R. Lowrance

2006-01-01

Given the importance of issues related to improved understanding and management of riparian ecosystems and buffers, the American Water Resources Association (AWRA) sponsored a Summer Specialty Conference in June 2004 at Olympic Valley, California, entitled 'Riparian Ecosystems and Buffers: Multiscale Structure, Function, and Management.' The primary objective...

32 CFR 651.14 - Integration with Army planning.

Code of Federal Regulations, 2014 CFR

2014-07-01

... be controversial. In most cases, local citizens and/or existing advisory groups should assist in... reduce or eliminate discussion of minor issues to help focus analyses. Such an approach will minimize... recommendations presented in the CEQ publication entitled “The National Environmental Policy Act: A Study of Its...

32 CFR 651.14 - Integration with Army planning.

Code of Federal Regulations, 2011 CFR

2011-07-01

... be controversial. In most cases, local citizens and/or existing advisory groups should assist in... reduce or eliminate discussion of minor issues to help focus analyses. Such an approach will minimize... recommendations presented in the CEQ publication entitled “The National Environmental Policy Act: A Study of Its...

32 CFR 651.14 - Integration with Army planning.

Code of Federal Regulations, 2010 CFR

2010-07-01

... be controversial. In most cases, local citizens and/or existing advisory groups should assist in... reduce or eliminate discussion of minor issues to help focus analyses. Such an approach will minimize... recommendations presented in the CEQ publication entitled “The National Environmental Policy Act: A Study of Its...

32 CFR 651.14 - Integration with Army planning.

Code of Federal Regulations, 2012 CFR

2012-07-01

... be controversial. In most cases, local citizens and/or existing advisory groups should assist in... reduce or eliminate discussion of minor issues to help focus analyses. Such an approach will minimize... recommendations presented in the CEQ publication entitled “The National Environmental Policy Act: A Study of Its...

32 CFR 651.14 - Integration with Army planning.

Code of Federal Regulations, 2013 CFR

2013-07-01

... be controversial. In most cases, local citizens and/or existing advisory groups should assist in... reduce or eliminate discussion of minor issues to help focus analyses. Such an approach will minimize... recommendations presented in the CEQ publication entitled “The National Environmental Policy Act: A Study of Its...

Governance and Free Education: Directions, Mechanisms and Policy Tensions

ERIC Educational Resources Information Center

Bray, Mark

2007-01-01

In 2006, the Department for International Development (DfID) of the United Kingdom Government issued a White Paper entitled "Eliminating World Poverty: Making Governance Work for Poor People." The DfID document observed that good governance requires attention to State capability, described at "the extent to which leaders and…

Why Academic Depth and Rigour in University-Based Coursework Matters for Prospective Teachers

ERIC Educational Resources Information Center

Rusznyak, Lee; Balfour, Robert; Van Vollenhoven, Willie; Sosibo, Lungi

2016-01-01

This special issue of "Perspectives in Education" arises from a symposium entitled "Academic depth and rigour in initial teacher education" jointly organised by four universities in South Africa. The symposium, held in October 2014, attracted 125 delegates from 18 South African higher education institutions (HEIs).…

14 CFR 406.141 - Motions.

Code of Federal Regulations, 2010 CFR

2010-01-01

..., at any time before the administrative law judge has issued an initial decision in the proceedings... that the party making the motion is entitled to a decision as a matter of law. The party making the..., including affidavits, to the motion. (c) Form and time. Except for oral motions heard on the record, a...

FACCCTS: Journal of the Faculty Association of California Community Colleges, 2001-2002.

ERIC Educational Resources Information Center

Martinez, Katherine, Ed.

2002-01-01

This document is comprised of four Faculty Association of California Community Colleges (FACCC) newsletters. The September 2001 issue is entitled "Many Voices, One Goal," and contains the following articles: "Growing Pains, Faculty's Role in Governance," and "AB 1725 and Other War Stories," among others. The issue…

Questioning Collectives and Agencies: A Commentary on Curricular Choices

ERIC Educational Resources Information Center

Arnold, Jenny

2015-01-01

This commentary explores theoretical alternatives for viewing the problem identified by Volny Fages and Virginie Albe in their article entitled Social issues in nanoscience and nanotechnology Master's degrees: The socio-political stakes of curricular choices. An approach to social research is suggested that would render visible the associations…

PREFACE: SPECIAL ISSUE OF ATMOSPHERIC ENVIRONMENT, FOR PARTICULATE MATTER: ATMOSPHERIC SCIENCES, EXPOSURE AND THE FOURTH COLLOQUIUM ON PM AND HUMAN HEALTH

EPA Science Inventory

In a continuing effort to improve communications among the atmospheric sciences, policy, and health communities, an international specialty conference was initiated in 2001 that took place in April 2003 in Pittsburgh, PA. The conference entitled, "Particulate Matter: Atmospheric...

Why Doesn't This Feel Empowering? The Challenges of Web-Based Intercultural Dialogue

ERIC Educational Resources Information Center

Bali, Maha

2014-01-01

Ellsworth's article entitled "Why doesn't this feel empowering? Working through the repressive myths of critical pedagogy" raises issues about the complex dynamics of implementing critical pedagogy in real classrooms, and the difficulties and paradoxes of putting the empowerment rhetoric into practice. This article analyses the…

Suggestopaedia-Canada.

ERIC Educational Resources Information Center

Racle, Gabriel

This issue presents an English translation and the original French version of the text of a speech delivered by Dr. Georgui Lozanov at the First International Congress of Hypnopaedia and Suggesto-hypnopaedia in Paris on May 29-30, 1976. The paper is entitled "A General Theory of Suggestion in the Communications Process and the Activation of…

Reaching Black Men. Commentary

ERIC Educational Resources Information Center

Gassman, Marybeth

2010-01-01

Journalist Elizabeth Redden brings to the surface several salient issues in her article entitled, "Reaching Black Men." First, she illuminates that fact that access is not enough when it comes to educating African American men. Second, she points to the importance of having campus-wide initiatives to support the success of Black men. And…

15 CFR 200.112 - Reports.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 15 Commerce and Foreign Trade 1 2013-01-01 2013-01-01 false Reports. 200.112 Section 200.112... FEES § 200.112 Reports. (a) Results of calibrations and other tests are issued to the customer as formal reports entitled, “National Institute of Standards & Technology Report of Calibration,” “National...

15 CFR 200.112 - Reports.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 15 Commerce and Foreign Trade 1 2011-01-01 2011-01-01 false Reports. 200.112 Section 200.112... FEES § 200.112 Reports. (a) Results of calibrations and other tests are issued to the customer as formal reports entitled, “National Institute of Standards & Technology Report of Calibration,” “National...

15 CFR 200.112 - Reports.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 15 Commerce and Foreign Trade 1 2014-01-01 2014-01-01 false Reports. 200.112 Section 200.112... FEES § 200.112 Reports. (a) Results of calibrations and other tests are issued to the customer as formal reports entitled, “National Institute of Standards & Technology Report of Calibration,” “National...

78 FR 36698 - Microbiology Devices; Reclassification of Nucleic Acid-Based Systems for Mycobacterium tuberculosis

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-19

... specimens from class III (premarket approval) into class II (special controls). FDA is also issuing the draft special controls guideline entitled ``Class II Special Controls Guideline: Nucleic Acid-Based In... regulatory controls needed to provide reasonable assurance of their safety and effectiveness. The three...

Doing School Choice Right: Preliminary Findings

ERIC Educational Resources Information Center

Harvey, James; Hill, Paul T.

2006-01-01

The Center on Reinventing Public Education (CRPE) has launched a new initiative entitled "Doing School Choice Right." Funded by the Bill and Melinda Gates, Annie E. Casey, and Lynde and Harry Bradley Foundations, the initiative's goal is to help state and local leaders handle practical issues whose resolution can determine whether school…

Mother/Child, Father/Child Relationships.

ERIC Educational Resources Information Center

Stevens, Joseph H., Jr., Ed.; Mathews, Marilyn, Ed.

This collection of papers on parent-child relationships consists of three research reports, six research reviews and two position papers on issues critical to research and practice. Papers included were selected on the basis of their relevance to the work of practitioners who counsel parents. The volume's four thematic sections are entitled: (1)…

76 FR 55108 - Notice of Receipt of Complaint; Solicitation of Comments Relating to the Public Interest

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-06

...Notice is hereby given that the U.S. International Trade Commission has received a complaint entitled In Re Certain Devices for Mobile Data Communication, DN 2843; the Commission is soliciting comments on any public interest issues raised by the complaint.

78 FR 70354 - Conceptual Example of a Proposed Risk Management Regulatory Framework Policy Statement

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-25

... NUCLEAR REGULATORY COMMISSION [NRC-2013-0254] Conceptual Example of a Proposed Risk Management... issuing a document entitled: ``White Paper on a Conceptual Example of a Proposed Risk Management... ``openness,'' a white paper on a Conceptual Example of a Proposed Risk Management Regulatory Framework (RMRF...

Computational membrane biophysics: From ion channel interactions with drugs to cellular function.

PubMed

Miranda, Williams E; Ngo, Van A; Perissinotti, Laura L; Noskov, Sergei Yu

2017-11-01

The rapid development of experimental and computational techniques has changed fundamentally our understanding of cellular-membrane transport. The advent of powerful computers and refined force-fields for proteins, ions, and lipids has expanded the applicability of Molecular Dynamics (MD) simulations. A myriad of cellular responses is modulated through the binding of endogenous and exogenous ligands (e.g. neurotransmitters and drugs, respectively) to ion channels. Deciphering the thermodynamics and kinetics of the ligand binding processes to these membrane proteins is at the heart of modern drug development. The ever-increasing computational power has already provided insightful data on the thermodynamics and kinetics of drug-target interactions, free energies of solvation, and partitioning into lipid bilayers for drugs. This review aims to provide a brief summary about modeling approaches to map out crucial binding pathways with intermediate conformations and free-energy surfaces for drug-ion channel binding mechanisms that are responsible for multiple effects on cellular functions. We will discuss post-processing analysis of simulation-generated data, which are then transformed to kinetic models to better understand the molecular underpinning of the experimental observables under the influence of drugs or mutations in ion channels. This review highlights crucial mathematical frameworks and perspectives on bridging different well-established computational techniques to connect the dynamics and timescales from all-atom MD and free energy simulations of ion channels to the physiology of action potentials in cellular models. This article is part of a Special Issue entitled: Biophysics in Canada, edited by Lewis Kay, John Baenziger, Albert Berghuis and Peter Tieleman. Copyright © 2017 Elsevier B.V. All rights reserved.

78 FR 61873 - Revisions to the Export Administration Regulations (EAR) To Make the Commerce Control List (CCL...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-04

...This final rule implements changes that were proposed on November 29, 2012 in a proposed rule entitled Revisions to the Export Administration Regulations (EAR) To Make the Commerce Control List (CCL) Clearer. The changes in the November 29 proposed rule were informed by public comments received in response to an advance notice of proposed rulemaking entitled Commerce Control List: Revising Descriptions of Items and Foreign Availability published as part of the President's Export Control Reform (ECR) Initiative on December 9, 2010. This final rule implements changes that can be made to the CCL without requiring changes to multilateral export control regime guidelines or lists. This final rule also makes conforming changes and minor clarifications as a result of the publication of two final rules implementing the Export Control Reform Initiative: the April 16, 2013 final rule entitled Revisions to the Export Administration Regulations: Initial Implementation of Export Control Reform; and the July 8, 2013 final rule entitled Revisions to the Export Administration Regulations: Military Vehicles; Vessels of War; Submersible Vessels, Oceanographic Equipment; Related Items; and Auxiliary and Miscellaneous Items that the President Determines No Longer Warrant Control under the United States Munitions List. Lastly, this final rule is making revisions to the EAR as a result of public comments received in response to the November 29 proposed rule and to a notice of inquiry (NOI) entitled Request for Public Comments on Shipping Tolerances for Export Licenses Issued by the Bureau of Industry and Security (BIS), that BIS published on July 5, 2012.

QPROT: Statistical method for testing differential expression using protein-level intensity data in label-free quantitative proteomics.

PubMed

Choi, Hyungwon; Kim, Sinae; Fermin, Damian; Tsou, Chih-Chiang; Nesvizhskii, Alexey I

2015-11-03

We introduce QPROT, a statistical framework and computational tool for differential protein expression analysis using protein intensity data. QPROT is an extension of the QSPEC suite, originally developed for spectral count data, adapted for the analysis using continuously measured protein-level intensity data. QPROT offers a new intensity normalization procedure and model-based differential expression analysis, both of which account for missing data. Determination of differential expression of each protein is based on the standardized Z-statistic based on the posterior distribution of the log fold change parameter, guided by the false discovery rate estimated by a well-known Empirical Bayes method. We evaluated the classification performance of QPROT using the quantification calibration data from the clinical proteomic technology assessment for cancer (CPTAC) study and a recently published Escherichia coli benchmark dataset, with evaluation of FDR accuracy in the latter. QPROT is a statistical framework with computational software tool for comparative quantitative proteomics analysis. It features various extensions of QSPEC method originally built for spectral count data analysis, including probabilistic treatment of missing values in protein intensity data. With the increasing popularity of label-free quantitative proteomics data, the proposed method and accompanying software suite will be immediately useful for many proteomics laboratories. This article is part of a Special Issue entitled: Computational Proteomics. Copyright © 2015 Elsevier B.V. All rights reserved.

Teaching Clinical Neurology with the PLATO IV Computer System

ERIC Educational Resources Information Center

Parker, Alan; Trynda, Richard

1975-01-01

A "Neurox" program entitled "Canine Neurological Diagnosis" developed at the University of Illinois College of Veterinary Medicine enables a student to obtain the results of 78 possible neurological tests or associated questions on a single case. A lesson and possible adaptations are described. (LBH)

NATURAL BIOATTENUATION OF TRICHLOROETHENE AT THE ST. JOSEPH, MICHIGAN SUPERFUND SITE

EPA Science Inventory

Data from the St. Joseph, Michigan, Superfund Site were used in a peer-reviewed video entitled "Natural Bioattenuation of Trichloroethene at the St. Joseph, Michigan Superfund Site." Computer visualizations of the data set show how trichloroethene, or TCE, can degrade under natu...

Signalling mechanisms in autophagy: an introduction to the issue.

PubMed

Lane, Jon D; Korolchuk, Viktor I; Murray, James T

2017-12-12

Essays in Biochemistry volume 61 (issue 6), entitled Signalling Mechanisms in Autophagy , covers a range of topics in autophagy signalling, touching on emerging new details on the mechanisms of autophagy regulation, novel aspects of selective autophagy and how autophagy functions in organelle homeostasis. It also looks at how autophagy research is leading to better understanding of human disease and plant biology that can be exploited for the benefit of society. © 2017 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society.

A European Flagship Programme on Extreme Computing and Climate

NASA Astrophysics Data System (ADS)

Palmer, Tim

2017-04-01

In 2016, an outline proposal co-authored by a number of leading climate modelling scientists from around Europe for a (c. 1 billion euro) flagship project on exascale computing and high-resolution global climate modelling was sent to the EU via its Future and Emerging Flagship Technologies Programme. The project is formally entitled "A Flagship European Programme on Extreme Computing and Climate (EPECC)"? In this talk I will outline the reasons why I believe such a project is needed and describe the current status of the project. I will leave time for some discussion.

Publisher's Note to “The association between kinematic risky driving among parents and their teenage children: Moderation by Shared Personality Characteristics”.

PubMed

2014-06-01

The Publisher would like to inform readers that the article entitled "The association between kinematic risky driving among parents and their teenage children: Moderation by Shared Personality Characteristics" by Johnathon P. Ehsani, Bruce Simons-Morton, Yunlong Xie,Sheila G. Klauer, and Paul S. Albert has been removed from this issue, as it had been incorrectly included here rather than in the special issue for which it was intended. The article will be published in the correct issue in the near future. This is to ensure the continuity of the special issue is not lost. The Publisher would like to apologize for any inconvenience caused.

Clinical Mass Spectrometry: Achieving Prominence in Laboratory Medicine

DOE Office of Scientific and Technical Information (OSTI.GOV)

Annesley, Thomas M.; Cooks, Robert G.; Herold, David A.

Each year the journal Clinical Chemistry publishes a January special issue on a topic that is relevant to the laboratory medicine community. In January 2016 the topic is mass spectrometry, and the issue is entitled “Clinical Mass Spectrometry: Achieving Prominence in Laboratory Medicine”. One popular feature in our issues is a Q&A on a topic, clearly in this case mass spectrometry. The journal is assembling a panel of 5-6 experts from various areas of mass spectrometry ranging from instrument manufacturing to practicing clinical chemists. Dick Smith is one of the scientist requested to participate in this special issue Q&A onmore » Mass Spectrometry. The Q&A Transcript is attached« less

"Pleiades Visions" for organ solo: A composition supported by documented research

NASA Astrophysics Data System (ADS)

Whitehouse, Matthew Robert

Pleiades Visions is a three-movement work for organ solo inspired by indigenous music and mythology associated with the Pleiades (Seven Sisters) star cluster. Three cultural groups are represented in Pleiades Visions. The first movement, entitled "Uluru," draws from Australian Aboriginal music and mythology. The second movement, entitled "...life on other worlds," is based loosely on a Quechan (Yuman) Indian song. The concluding movement, entitled "Mauna Kea," is inspired by the opening lines of the Kumulipo, a creation chant of the Native Hawaiian culture. The source material for Pleiades Visions was identified through research incorporating techniques from the fields of cultural astronomy and ethnomusicology. This research represents a new line of inquiry for both fields. This document situates Pleiades Visions in the context of the organ literature, and suggests that Pleiades Visions might be the first organ work with a cultural astronomy inspiration. It also describes the research undergirding Pleiades Visions, demonstrates the manner in which that research informed the composition of the work, and addresses issues surrounding the use of indigenous source material in a culturally sensitive manner.

Science Comic Strips

ERIC Educational Resources Information Center

Kim, Dae Hyun; Jang, Hae Gwon; Shin, Dong Sun; Kim, Sun-Ja; Yoo, Chang Young; Chung, Min Suk

2012-01-01

Science comic strips entitled Dr. Scifun were planned to promote science jobs and studies among professionals (scientists, graduate and undergraduate students) and children. To this end, the authors collected intriguing science stories as the basis of scenarios, and drew four-cut comic strips, first on paper and subsequently as computer files.…

Computer Simulation of Developmental Processes and ...

EPA Pesticide Factsheets

see attached presentation slides Dr. Knudsen has been invited to give a lecture at XIV International Congress of Toxicology (IUTOX) in Merida-Mexico October 2-6, 2016. He was invited to speak in a workshop on “Developmental Toxicology, Different Models, Different Endpoints” and will give a lecture entitled

Functionalized lipids and surfactants for specific applications.

PubMed

Kepczynski, Mariusz; Róg, Tomasz

2016-10-01

Synthetic lipids and surfactants that do not exist in biological systems have been used for the last few decades in both basic and applied science. The most notable applications for synthetic lipids and surfactants are drug delivery, gene transfection, as reporting molecules, and as support for structural lipid biology. In this review, we describe the potential of the synergistic combination of computational and experimental methodologies to study the behavior of synthetic lipids and surfactants embedded in lipid membranes and liposomes. We focused on select cases in which molecular dynamics simulations were used to complement experimental studies aiming to understand the structure and properties of new compounds at the atomistic level. We also describe cases in which molecular dynamics simulations were used to design new synthetic lipids and surfactants, as well as emerging fields for the application of these compounds. This article is part of a Special Issue entitled: Biosimulations edited by Ilpo Vattulainen and Tomasz Róg. Copyright © 2016 Elsevier B.V. All rights reserved.

Analyst-to-Analyst Variability in Simulation-Based Prediction

DOE Office of Scientific and Technical Information (OSTI.GOV)

Glickman, Matthew R.; Romero, Vicente J.

This report describes findings from the culminating experiment of the LDRD project entitled, "Analyst-to-Analyst Variability in Simulation-Based Prediction". For this experiment, volunteer participants solving a given test problem in engineering and statistics were interviewed at different points in their solution process. These interviews are used to trace differing solutions to differing solution processes, and differing processes to differences in reasoning, assumptions, and judgments. The issue that the experiment was designed to illuminate -- our paucity of understanding of the ways in which humans themselves have an impact on predictions derived from complex computational simulations -- is a challenging and openmore » one. Although solution of the test problem by analyst participants in this experiment has taken much more time than originally anticipated, and is continuing past the end of this LDRD, this project has provided a rare opportunity to explore analyst-to-analyst variability in significant depth, from which we derive evidence-based insights to guide further explorations in this important area.« less

Molecular dynamics simulations of biological membranes and membrane proteins using enhanced conformational sampling algorithms☆

PubMed Central

Mori, Takaharu; Miyashita, Naoyuki; Im, Wonpil; Feig, Michael; Sugita, Yuji

2016-01-01

This paper reviews various enhanced conformational sampling methods and explicit/implicit solvent/membrane models, as well as their recent applications to the exploration of the structure and dynamics of membranes and membrane proteins. Molecular dynamics simulations have become an essential tool to investigate biological problems, and their success relies on proper molecular models together with efficient conformational sampling methods. The implicit representation of solvent/membrane environments is reasonable approximation to the explicit all-atom models, considering the balance between computational cost and simulation accuracy. Implicit models can be easily combined with replica-exchange molecular dynamics methods to explore a wider conformational space of a protein. Other molecular models and enhanced conformational sampling methods are also briefly discussed. As application examples, we introduce recent simulation studies of glycophorin A, phospholamban, amyloid precursor protein, and mixed lipid bilayers and discuss the accuracy and efficiency of each simulation model and method. This article is part of a Special Issue entitled: Membrane Proteins. Guest Editors: J.C. Gumbart and Sergei Noskov. PMID:26766517

Systems biology of stored blood cells: can it help to extend the expiration date?

PubMed

Paglia, Giuseppe; Palsson, Bernhard Ø; Sigurjonsson, Olafur E

2012-12-05

With increasingly stringent regulations regarding deferral and elimination of blood donors it will become increasingly important to extend the expiration date of blood components beyond the current allowed storage periods. One reason for the storage time limit for blood components is that platelets and red blood cells develop a condition called storage lesions during their storage in plastic blood containers. Systems biology provides comprehensive bio-chemical descriptions of organisms through quantitative measurements and data integration in mathematical models. The biological knowledge for a target organism can be translated in a mathematical format and used to compute physiological properties. The use of systems biology represents a concrete solution in the study of blood cell storage lesions, and it may open up new avenues towards developing better storage methods and better storage media, thereby extending the storage period of blood components. This article is part of a Special Issue entitled: Integrated omics. Copyright © 2012 Elsevier B.V. All rights reserved.

Youth Apprenticeship: A School-to-Work Transition Program. Hot Topic.

ERIC Educational Resources Information Center

North Carolina Univ., Greensboro. School of Education.

SERVE offers a series of publications entitled "Hot Topics," research-based documents which focus on relevant issues of the day that are important in the region. This document, the first in a series of publications, is a practical guidebook to designing and developing youth apprenticeship programs to prepare noncollege-bound high school…

75 FR 39667 - Availability for Non-Exclusive or Partially Exclusive Licensing of a U.S. Patent Application

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-12

..., which issued on December 15, 2009, entitled ``Use of Shigella Invaplex to Transport Functional Proteins... Functional Proteins and Transcriptionally Active Nucleic Acids Across Mammalian Cell Membranes In Vitro and... functional proteins and biologically active nucleic acids, across eukaryotic cell membranes. Brenda S. Bowen...

14 CFR 21.21 - Issue of type certificate: normal, utility, acrobatic, commuter, and transport category aircraft...

Code of Federal Regulations, 2014 CFR

2014-01-01

...; aircraft engines; propellers. 21.21 Section 21.21 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION...; manned free balloons; special classes of aircraft; aircraft engines; propellers. An applicant is entitled... category, or for a manned free balloon, special class of aircraft, or an aircraft engine or propeller, if...

14 CFR 21.21 - Issue of type certificate: normal, utility, acrobatic, commuter, and transport category aircraft...

Code of Federal Regulations, 2013 CFR

2013-01-01

...; aircraft engines; propellers. 21.21 Section 21.21 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION...; manned free balloons; special classes of aircraft; aircraft engines; propellers. An applicant is entitled... category, or for a manned free balloon, special class of aircraft, or an aircraft engine or propeller, if...

14 CFR 21.21 - Issue of type certificate: normal, utility, acrobatic, commuter, and transport category aircraft...

Code of Federal Regulations, 2012 CFR

2012-01-01

...; aircraft engines; propellers. 21.21 Section 21.21 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION...; manned free balloons; special classes of aircraft; aircraft engines; propellers. An applicant is entitled... category, or for a manned free balloon, special class of aircraft, or an aircraft engine or propeller, if...

A Brief Note on Evidence-Centered Design as a Mechanism for Assessment Development and Evaluation

ERIC Educational Resources Information Center

Bond, Lloyd

2014-01-01

Lloyd Bond comments here on the Focus article in this issue of "Measurement: Interdisciplinary Research and Perspectives". The Focus article is entitled: "How Task Features Impact Evidence from Assessments Embedded in Simulations and Games" (Russell G. Almond, Yoon Jeon Kim, Gertrudes Velasquez, and Valerie J. Shute). Bond…

Errors and Allegations about Research on Homework

ERIC Educational Resources Information Center

Marzano, Robert J.; Pickering, Debra J.

2007-01-01

This article provides a response to Kohn's article entitled "Abusing Research: The Study of Homework and Other Examples" that appeared in the September 2006 issue of the "Kappan." There Kohn asserted that many of those who conduct research on homework and report on that research misrepresent research findings. He specifically mentioned a set of…

The Changed/Changing Educational Scene: The State of the Art.

ERIC Educational Resources Information Center

Bunke, Clinton R.; And Others

A special attempt was made to organize this document in terms of the requirements of its readership (members of the Commission on Children, White House Conference, 1980). To this end, the first section, entitled "Gaining Perspective," provides an overview of developments, expectations, issues, dynamics, culture shock, and future trends in…

A Winning Combination: An Alcohol, Other Drug, and Traffic Safety Handbook for College Campuses.

ERIC Educational Resources Information Center

Anderson, David, Ed.

This manual addresses the social and legal issues facing college administrators today in dealing with alcohol and other drug problems. It is a guide for colleges and universities to develop individualized alcohol, drug, and traffic safety programs. The first part, entitled "Insights," presents background articles by professionals in higher…

Aging Parents & Dilemmas of Their Children.

ERIC Educational Resources Information Center

Smith, Bert Kruger; And Others

After an opening series of vignettes which describe the frustrations of adults who care for aging and infirm parents, this pamphlet addresses the issue of aging parents and the dilemmas they pose for their children. In particular, it describes a model entitled "As Parents Grow Older" (APGO) that originated as a service for families of…

Diversity in the Middle: Broadening Perspectives on Intermediary Levels of School System Improvement

ERIC Educational Resources Information Center

Anderson, Stephen E.

2013-01-01

Purpose: The purpose of this paper is to present the author's commentary on the special issue of "Journal of Educational Administration" entitled "Systemwide Reform: Examining Districts under Pressure". Design/methodology/approach: The major thesis of this commentary and reflection on the preceding papers is that there is…

12 CFR 960.1 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... LETTERS OF CREDIT § 960.1 Definitions. As used in this part: Applicant means a person or entity at whose request or for whose account a standby letter of credit is issued. Beneficiary means a person or entity who, under the terms of a standby letter of credit, is entitled to have its complying presentation...

Food and My World: My Health My World.

ERIC Educational Resources Information Center

Tharp, Barbara; Dresden, Judith; Denk, James; Moreno, Nancy

This curriculum guide for students in grades K-4 is part of the My Health My World Series. It explores environmental issues, focusing on food and the environment. The unit includes (1) an activities guide for teachers entitled, "Food and My World," which presents activity-based lessons that entice students to discover concepts in…

39 CFR 960.12 - When an application may be filed.

Code of Federal Regulations, 2014 CFR

2014-07-01

... before the Board of Contract Appeals, the Board of Contract Appeals decision on quantum. When the Board decides only entitlement and remands the issue of quantum to the parties, the final disposition occurs when the parties execute an agreement on quantum, or if the parties cannot agree on quantum and...

39 CFR 960.12 - When an application may be filed.

Code of Federal Regulations, 2013 CFR

2013-07-01

... before the Board of Contract Appeals, the Board of Contract Appeals decision on quantum. When the Board decides only entitlement and remands the issue of quantum to the parties, the final disposition occurs when the parties execute an agreement on quantum, or if the parties cannot agree on quantum and...

39 CFR 960.12 - When an application may be filed.

Code of Federal Regulations, 2012 CFR

2012-07-01

... before the Board of Contract Appeals, the Board of Contract Appeals decision on quantum. When the Board decides only entitlement and remands the issue of quantum to the parties, the final disposition occurs when the parties execute an agreement on quantum, or if the parties cannot agree on quantum and...

39 CFR 960.12 - When an application may be filed.

Code of Federal Regulations, 2011 CFR

2011-07-01

... before the Board of Contract Appeals, the Board of Contract Appeals decision on quantum. When the Board decides only entitlement and remands the issue of quantum to the parties, the final disposition occurs when the parties execute an agreement on quantum, or if the parties cannot agree on quantum and...

Council of Europe News-Letter 4/72.

ERIC Educational Resources Information Center

Council of Europe, Strasbourg (France). Documentation Center for Education in Europe.

Excerpts from "Teacher Education and Training" (the James' Report), issued in the United Kingdom early in 1972, comprise the bulk of this newsletter. James recommends that "all teachers should be entitled to release with pay for inservice education and training on a scale not less than the equivalent of one term in every seven…

A Government Action Approach to First Amendment Analysis.

ERIC Educational Resources Information Center

Walden, Ruth

1992-01-01

Suggests focusing on the actions of government that restrict free expression rather than focusing on the values served by freedom of expression. Bases the approach on the premise that the court's function is to determine when a particular government action violates the First Amendment, not whether the expression at issue is entitled to…

Indigenous African Knowledge Systems and Innovation in Higher Education in South Africa

ERIC Educational Resources Information Center

Higgs, P.; Higgs, L. G.; Venter, E.

2003-01-01

The importance of innovation in higher education is recognised in South African educational discourse. The South African White Paper on Science and Technology, issued in September 1996 and entitled, "Preparing for the 21st Century", states that, "the White Paper is built upon the twin concepts of "innovation" and a…

Religious Education in Greece: A New Curriculum, an Old Issue

ERIC Educational Resources Information Center

Koukounaras Liagkis, Marios

2015-01-01

Religious Education (RE) in Greece is a compulsory school subject according the 2011 new framework for compulsory education, entitled "New School". This article focuses on two statutory documents for RE, "The Curriculum for RE" and the "The Teacher's Guide for RE", and the pilot scheme of the new curriculum running in…

ACHP | News | ACHP Issue Spotlight: Transmission Lines in the West

Science.gov Websites

Search skip specific nav links Home arrow News arrow ACHP Announces GAO Report Calling for Improved Data on Historic Properties ACHP Announces GAO Report Calling for Improved Data on Historic Properties The U.S. Government Accountability Office (GAO) recently released a report entitled "Improved Data

The next Stages in Researching Water Fluoridation: Evaluation and Surveillance

ERIC Educational Resources Information Center

Downer, Martin C.; Blinkhorn, Anthony S.

2007-01-01

Objective: (1) to provide a commentary on a conference held at the University of Manchester entitled Researching Water Fluoridation: Evaluation and Surveillance; (2) to synthesize from the proceedings of the meeting suggestions for future research and public health surveillance. Method: The main points and problematic issues raised by the speakers…

76 FR 40744 - Notice of Receipt of Complaint; Solicitation of Comments Relating to the Public Interest

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-11

... entitled In Re Electronic Digital Media Devices and Components Thereof, DN 2827; the Commission is soliciting comments on any public interest issues raised by the complaint. FOR FURTHER INFORMATION CONTACT... Commission, 500 E Street, SW., Washington, DC 20436, telephone (202) 205-2000. General information concerning...

41 CFR 102-79.90 - What criteria must Executive agencies consider when evaluating antenna siting requests?

Code of Federal Regulations, 2010 CFR

2010-07-01

... radiofrequency exposure, ET Docket No. 93-62, entitled “Guidelines for Evaluating the Environmental Effects of Radiofrequency Radiation,” issued August 1, 1996, and any other order on reconsideration relating to radiofrequency guidelines and their enforcement. These are updated guidelines for meeting health concerns that...

76 FR 67688 - Notice of Preliminary Determination of Sales at Less Than Fair Value, Postponement of Final...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-02

... investigation on April 19, 2011 (see Initiation of Antidumping Duty Investigations: Bottom Mount Combination..., Electrolux requested that it be treated as a mandatory respondent in this investigation. On May 18, 2011, we... this investigation and issued a questionnaire to Electrolux. See Memorandum entitled ``Inclusion of...

75 FR 80798 - Availability for Exclusive, Non-Exclusive, or Partially-Exclusive Licensing of Inventions...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-23

... Partially-Exclusive Licensing of Inventions Concerning an Inactivated Dengue Virus Vaccine and a Method and Kit for Detection of Dengue Virus AGENCY: Department of the Army, DoD. ACTION: Notice. SUMMARY... which issued July 3, 2001, entitled ``Inactivated Dengue Virus Vaccine,'' and U.S. Patent 6,190,859...

Custody and Access Issues in Schools. Law Matters.

ERIC Educational Resources Information Center

Hoffer, Marion

2002-01-01

In cases of marital separation, educators should determine a person's entitlement to a child before giving out information about the child. Courts may have denied a parent access to a child or, in the case of domestic violence, criminal charges may be involved. Educators should avoid giving evidence, but should cooperate with court-appointed…

22 CFR 42.42 - Petitions for immediate relative or preference status.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Petitions for immediate relative or preference status. 42.42 Section 42.42 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF... may not issue a visa to an alien as an immediate relative entitled to status under 201(b), a family...

22 CFR 42.42 - Petitions for immediate relative or preference status.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Petitions for immediate relative or preference status. 42.42 Section 42.42 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF... may not issue a visa to an alien as an immediate relative entitled to status under 201(b), a family...

22 CFR 42.42 - Petitions for immediate relative or preference status.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Petitions for immediate relative or preference status. 42.42 Section 42.42 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF... may not issue a visa to an alien as an immediate relative entitled to status under 201(b), a family...

22 CFR 42.42 - Petitions for immediate relative or preference status.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Petitions for immediate relative or preference status. 42.42 Section 42.42 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF... may not issue a visa to an alien as an immediate relative entitled to status under 201(b), a family...

22 CFR 42.42 - Petitions for immediate relative or preference status.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Petitions for immediate relative or preference status. 42.42 Section 42.42 Foreign Relations DEPARTMENT OF STATE VISAS VISAS: DOCUMENTATION OF... may not issue a visa to an alien as an immediate relative entitled to status under 201(b), a family...

Video Recording and the Research Process

ERIC Educational Resources Information Center

Leung, Constant; Hawkins, Margaret R.

2011-01-01

This is a two-part discussion. Part 1 is entitled "English Language Learning in Subject Lessons", and Part 2 is titled "Video as a Research Tool/Counterpoint". Working with different research concerns, the authors attempt to draw attention to a set of methodological and theoretical issues that have emerged in the research process using video data.…

39 CFR 960.12 - When an application may be filed.

Code of Federal Regulations, 2010 CFR

2010-07-01

... before the Board of Contract Appeals, the Board of Contract Appeals decision on quantum. When the Board decides only entitlement and remands the issue of quantum to the parties, the final disposition occurs when the parties execute an agreement on quantum, or if the parties cannot agree on quantum and...

78 FR 46969 - Human Immunodeficiency Virus Patient-Focused Drug Development and Human Immunodeficiency Virus...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-02

... for the notice of public meeting entitled ``Human Immunodeficiency Virus (HIV) Patient-Focused Drug Development and HIV Cure Research,'' published in the Federal Register of May 21, 2013 (78 FR 29755). In that... HIV, symptoms experienced because of HIV or its treatment, and issues related to HIV cure research...

75 FR 21632 - Draft Guidance for Industry and Food and Drug Administration Staff; Total Product Life Cycle...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-26

...] Draft Guidance for Industry and Food and Drug Administration Staff; Total Product Life Cycle: Infusion... the draft guidance document entitled ``Total Product Life Cycle: Infusion Pump--Premarket Notification... this issue of the Federal Register, FDA is announcing a public meeting regarding external infusion...

31 CFR 501.727 - Motion for summary disposition.

Code of Federal Regulations, 2014 CFR

2014-07-01

...). (b) Decision on motion. The Administrative Law Judge may promptly decide the motion for summary disposition or may defer decision on the motion. The Administrative Law Judge shall issue an order granting a... fact and the party making the motion is entitled to a summary disposition as a matter of law. (c) A...

31 CFR 501.727 - Motion for summary disposition.

Code of Federal Regulations, 2013 CFR

2013-07-01

...). (b) Decision on motion. The Administrative Law Judge may promptly decide the motion for summary disposition or may defer decision on the motion. The Administrative Law Judge shall issue an order granting a... fact and the party making the motion is entitled to a summary disposition as a matter of law. (c) A...

31 CFR 501.727 - Motion for summary disposition.

Code of Federal Regulations, 2012 CFR

2012-07-01

...). (b) Decision on motion. The Administrative Law Judge may promptly decide the motion for summary disposition or may defer decision on the motion. The Administrative Law Judge shall issue an order granting a... fact and the party making the motion is entitled to a summary disposition as a matter of law. (c) A...

31 CFR 501.727 - Motion for summary disposition.

Code of Federal Regulations, 2011 CFR

2011-07-01

...). (b) Decision on motion. The Administrative Law Judge may promptly decide the motion for summary disposition or may defer decision on the motion. The Administrative Law Judge shall issue an order granting a... fact and the party making the motion is entitled to a summary disposition as a matter of law. (c) A...

Real Estate Tax Exemption for Continuing Education Programs.

ERIC Educational Resources Information Center

Charters, Alexander N.

A court case in which the issue was whether Syracuse University was entitled to tax exemption for certain real property used for administrative offices, classrooms, student housing, and parking lots by its continuing education programs, particularly the Continuing Education Center for the Public Service, is presented. The finding of the Court is…

12 CFR 552.4 - Charter amendments.

Code of Federal Regulations, 2013 CFR

2013-01-01

... at the time of adoption, if adopted without change and filed with OTS within 30 days after adoption... be issued from time to time as authorized by the board of directors without further approval of... Section 5 (or in any supplementary sections hereto) shall entitle the holders of any class of a series of...

12 CFR 552.4 - Charter amendments.

Code of Federal Regulations, 2011 CFR

2011-01-01

... at the time of adoption, if adopted without change and filed with OTS within 30 days after adoption... be issued from time to time as authorized by the board of directors without further approval of... Section 5 (or in any supplementary sections hereto) shall entitle the holders of any class of a series of...

12 CFR 552.4 - Charter amendments.

Code of Federal Regulations, 2012 CFR

2012-01-01

... at the time of adoption, if adopted without change and filed with OTS within 30 days after adoption... be issued from time to time as authorized by the board of directors without further approval of... Section 5 (or in any supplementary sections hereto) shall entitle the holders of any class of a series of...

78 FR 15746 - Compendium of Analyses To Investigate Select Level 1 Probabilistic Risk Assessment End-State...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-12

... NUCLEAR REGULATORY COMMISSION [NRC-2013-0047] Compendium of Analyses To Investigate Select Level 1...) has issued for public comment a document entitled: Compendium of Analyses to Investigate Select Level... begin the search, select ``ADAMS Public Documents'' and then select ``Begin Web- based ADAMS Search...

27 CFR 478.49 - Duration of license.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 3 2010-04-01 2010-04-01 false Duration of license. 478....49 Duration of license. The license entitles the person to whom issued to engage in the business or activity specified on the license, within the limitations of the Act and the regulations contained in this...

After the Cold War: A New Calculus for Science and Security

ERIC Educational Resources Information Center

Wallerstein, Mitchel

2003-01-01

Just more than twenty years ago, the author had the privilege of directing a National Academy of Sciences panel that issued a report entitled "Scientific Communication and National Security," known informally as the Corson Report, after Dale Corson, the panel's chair and president emeritus of Cornell University. Thus, for him, today's discussions…

77 FR 58591 - Report on Waste Burial Charges: Changes in Decommissioning Waste Disposal Costs at Low-Level...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-21

... NUCLEAR REGULATORY COMMISSION [NRC-2010-0362] Report on Waste Burial Charges: Changes in Decommissioning Waste Disposal Costs at Low-Level Waste Burial Facilities AGENCY: Nuclear Regulatory Commission... Commission) has issued for public comment a document entitled: NUREG-1307 Revision 15, ``Report on Waste...

77 FR 18860 - Certain Consumer Electronics, Including Mobile Phones and Tablets; Notice of Receipt of Complaint...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-28

... INTERNATIONAL TRADE COMMISSION [DN 2885] Certain Consumer Electronics, Including Mobile Phones and.... International Trade Commission has received a complaint entitled Certain Consumer Electronics, Including Mobile... electronics, including mobile phones and tablets. The complaint names as respondents ASUSTeK Computer, Inc. of...

Postdoctoral Fellowship Program in Educational Research. Final Technical Report.

ERIC Educational Resources Information Center

Morgan, William P.

During his postdoctoral fellowship year, Dr. Morgan took formal course work in computer programing, advanced research design, projective techniques, the physiology of aging, and hypnosis. He also attended weekly seminars in the Institute of Environmental Stress and conducted an investigation entitled "The Alteration of Perceptual and Metabolic…

Grand challenge problems in environmental modeling and remediation: groundwater contaminant transport

DOE Office of Scientific and Technical Information (OSTI.GOV)

Todd Arbogast; Steve Bryant; Clint N. Dawson

1998-08-31

This report describes briefly the work of the Center for Subsurface Modeling (CSM) of the University of Texas at Austin (and Rice University prior to September 1995) on the Partnership in Computational Sciences Consortium (PICS) project entitled Grand Challenge Problems in Environmental Modeling and Remediation: Groundwater Contaminant Transport.

Prospects for Educational Telecomputing: Selected Readings.

ERIC Educational Resources Information Center

Tinker, Robert F., Ed.; Kapisovsky, Peggy M., Ed.

The purpose of this collection of readings was to stimulate debate on the role of educational telecomputing in school reform and restructuring, and how efforts from the public and private sector can coordinate to bring about these changes. The 14 papers are entitled: (1) "Linking for Learning: Computer-and-Communications Network Support for…

Predicting Precipitation in Darwin: An Experiment with Markov Chains

ERIC Educational Resources Information Center

Boncek, John; Harden, Sig

2009-01-01

As teachers of first-year college mathematics and science students, the authors are constantly on the lookout for simple classroom exercises that improve their students' analytical and computational skills. In this article, the authors outline a project entitled "Predicting Precipitation in Darwin." In this project, students: (1) analyze…

Utilizing Modern Technology in Adult and Continuing Education Programs.

ERIC Educational Resources Information Center

New York State Education Dept., Albany. Bureau of Curriculum Development.

This publication, designed as a supplement to the manual entitled "Managing Programs for Adults" (1983), provides guidelines for establishing or expanding the use of video and computers by administration and staff of adult education programs. The first section presents the use of video technology for program promotion, instruction, and staff…

Messages to Gail

ERIC Educational Resources Information Center

Selfe, Cindy, Ed.

2012-01-01

At the Computers and Writing 2011 Conference in Ann Arbor, Michigan, Gail E. Hawisher was celebrated for her many contributions to the field. At that conference, Hawisher gave a keynote address entitled "Our Work in the Profession: The Here and Now of the Future." This video publication includes contributions from scholars who wanted to share…

28 CFR 523.1 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INMATE ADMISSION, CLASSIFICATION, AND TRANSFER COMPUTATION OF SENTENCE Good Time § 523.1 Definitions. (a) Statutory good time means a credit to a sentence as authorized by 18 U.S.C. 4161. The total amount of statutory good time which an inmate is entitled to have...

28 CFR 523.1 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INMATE ADMISSION, CLASSIFICATION, AND TRANSFER COMPUTATION OF SENTENCE Good Time § 523.1 Definitions. (a) Statutory good time means a credit to a sentence as authorized by 18 U.S.C. 4161. The total amount of statutory good time which an inmate is entitled to have...

28 CFR 523.1 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INMATE ADMISSION, CLASSIFICATION, AND TRANSFER COMPUTATION OF SENTENCE Good Time § 523.1 Definitions. (a) Statutory good time means a credit to a sentence as authorized by 18 U.S.C. 4161. The total amount of statutory good time which an inmate is entitled to have...

28 CFR 523.1 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INMATE ADMISSION, CLASSIFICATION, AND TRANSFER COMPUTATION OF SENTENCE Good Time § 523.1 Definitions. (a) Statutory good time means a credit to a sentence as authorized by 18 U.S.C. 4161. The total amount of statutory good time which an inmate is entitled to have...

28 CFR 523.1 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INMATE ADMISSION, CLASSIFICATION, AND TRANSFER COMPUTATION OF SENTENCE Good Time § 523.1 Definitions. (a) Statutory good time means a credit to a sentence as authorized by 18 U.S.C. 4161. The total amount of statutory good time which an inmate is entitled to have...

Steroid promiscuity: Diversity of enzyme action. Preface.

PubMed

Lathe, Richard; Kotelevtsev, Yuri; Mason, J Ian

2015-07-01

This Special Issue on the topic of Steroid and Sterol Signaling: Promiscuity and Diversity, dwells on the growing realization that the 'one ligand, one binding site' and 'one enzyme, one reaction' concepts are out of date. Focusing on cytochromes P450 (CYP), hydroxysteroid dehydrogenases (HSDs), and related enzymes, the Special Issue highlights that a single enzyme can bind to diverse substrates, and in different conformations, and can catalyze multiple different conversions (and in different directions), thereby, generating an unexpectedly wide spectrum of ligands that can have subtly different biological actions. This article is part of a Special Issue entitled 'Steroid/Sterol Signaling' . Copyright © 2015 Elsevier Ltd. All rights reserved.

CHARMM additive and polarizable force fields for biophysics and computer-aided drug design.

PubMed

Vanommeslaeghe, K; MacKerell, A D

2015-05-01

Molecular Mechanics (MM) is the method of choice for computational studies of biomolecular systems owing to its modest computational cost, which makes it possible to routinely perform molecular dynamics (MD) simulations on chemical systems of biophysical and biomedical relevance. As one of the main factors limiting the accuracy of MD results is the empirical force field used, the present paper offers a review of recent developments in the CHARMM additive force field, one of the most popular biomolecular force fields. Additionally, we present a detailed discussion of the CHARMM Drude polarizable force field, anticipating a growth in the importance and utilization of polarizable force fields in the near future. Throughout the discussion emphasis is placed on the force fields' parametrization philosophy and methodology. Recent improvements in the CHARMM additive force field are mostly related to newly found weaknesses in the previous generation of additive force fields. Beyond the additive approximation is the newly available CHARMM Drude polarizable force field, which allows for MD simulations of up to 1μs on proteins, DNA, lipids and carbohydrates. Addressing the limitations ensures the reliability of the new CHARMM36 additive force field for the types of calculations that are presently coming into routine computational reach while the availability of the Drude polarizable force fields offers an inherently more accurate model of the underlying physical forces driving macromolecular structures and dynamics. This article is part of a Special Issue entitled "Recent developments of molecular dynamics". Copyright © 2014 Elsevier B.V. All rights reserved.

78 FR 35622 - Northwest Pipeline GP; Notice of Intent To Prepare an Environmental Assessment for the Proposed...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-13

... Station and Request for Comments on Environmental Issues The staff of the Federal Energy Regulatory... adjacent to the proposed meter station with a fact sheet prepared by the FERC entitled ``An Interstate... construct and operate a new LNG meter station and associated piping within the yard of its existing Plymouth...

Creative, Professional, and Moral Wherewithal in the Schooling of Immigrant Students

ERIC Educational Resources Information Center

Sanchez, Patricia

2012-01-01

The author is grateful that this journal has taken on the production of a special theme issue entitled "Immigration and Teacher Education: The Crisis and the Opportunity." In her estimation, the "crisis" is not so much that the United States may indeed continue to enroll more immigrant children and youth in its schooling system…

Media and Violence. Part One: Making the Connections. Media & Values 62.

ERIC Educational Resources Information Center

Silver, Rosalind, Ed.

1993-01-01

This issue of "Media & Values" explores the influence of mass media and violence in our society. The essays present various interpretations of that influence and the implications for the society. A special section entitled "Media and Violence Forum" contains 10 articles. Articles include: (1) "No Doubt About It - TV Violence Affects Behavior"…

International trends in health science librarianship part 20: Russia.

PubMed

Murphy, Jeannette; Jargin, Serge

2017-03-01

This is the last in a series of articles exploring international trends in health science librarianship in the 21st century. The focus of the present issue is Russia. The next feature column will initiate a new series entitled New Directions in Health Science Librarianship. The first contribution will be from Australia. JM. © 2017 Health Libraries Group.

77 FR 23116 - Privacy Act of 1974; Implementation

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-18

... DEPARTMENT OF JUSTICE 28 CFR Part 16 [CPCLO Order No. 009-2012] Privacy Act of 1974... Department) is issuing a final rule for a new Department-wide Privacy Act system of records entitled, Debt...), (3), and (4); (e)(1), (2), (3), (4)(G), (H) and (I), (5) and (8); (f) and (g) of the Privacy Act for...

77 FR 71404 - Notice of Intent to License Government-Owned Inventions; Intent to License on a Partially...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-30

... DEPARTMENT OF DEFENSE Department of the Army Notice of Intent to License Government-Owned Inventions; Intent to License on a Partially-Exclusive Basis AGENCY: Department of the Army, DoD. ACTION..., issued 07/ 28/2009 and entitled ``Radiation source with self-aligning optics,'' U.S. Patent 7,852,469...

Correction to “Apollo 11 Mission Commemorated”

NASA Astrophysics Data System (ADS)

Showstack, Randy

2009-08-01

In the 28 July 2009 issue of Eos (90(30), 258), a date was incorrect in the news item entitled “Apollo 11 Mission Commemorated.” NASA astronaut Eugene Cernan was referring to the 1970s, not the 1960s, in talking about his expectation of when humans would be back on the Moon. Eos regrets this error.

Post-War Trauma and Reconciliation in Bosnia-Herzegovina: Observations, Experiences, and Implications for Marriage and Family Therapy.

ERIC Educational Resources Information Center

Nelson, Briana S.

2003-01-01

The 1992-1995 war in Bosnia-Herzegovina caused mush devastation in that region of the world. This article describes the themes and issues that emerged from information gained from interviews with Bosnian professionals through a project entitled "Trauma and Reconciliation in Bosnia-Herzegovina." Recommendations and implications for family…

"Forest Grove School District v. T.A.": The Supreme Court and Unilateral Private Placements

ERIC Educational Resources Information Center

Yell, Mitchell L.; Katsiyannis, Antonis; Collins, Terri S.

2010-01-01

On June 22, 2009, the U.S. Supreme Court issued its decision in the case "Forest Grove School District v. T.A." (hereafter "Forest Grove"). In "Forest Grove," the High Court answered the question of whether the parents of students with disabilities are entitled to reimbursement for the costs associated with placing…

12 CFR 261b.1 - Basis and scope.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Basis and scope. 261b.1 Section 261b.1 Banks... REGARDING PUBLIC OBSERVATION OF MEETINGS § 261b.1 Basis and scope. This part is issued by the Board of... public is entitled to the fullest practicable information regarding the decision making processes of the...

Reforms in Pedagogy and the Confucian Tradition: Looking below the Surface

ERIC Educational Resources Information Center

Ho, Felix M.

2018-01-01

This Forum article addresses some of the issues raised in the article by Ying-Syuan Huang and Anila Asghar's paper entitled: "Science education reform in Confucian learning cultures: teachers' perspectives on policy and practice in Taiwan." An attempt is made to highlight the need for a more nuanced approach in considering the Confucian…

32 CFR 534.3 - Allowable expenses for witnesses.

Code of Federal Regulations, 2011 CFR

2011-07-01

... the trial in obedience to such subpoena, is entitled to mileage between his residence and the place of... civilian by a military court or board which has not express statutory authority to issue such process, such... Regulations. (See 6 Comp. Gen. 712.) (ii) There is no authority for payment by the Government of fees to an...

32 CFR 534.3 - Allowable expenses for witnesses.

Code of Federal Regulations, 2012 CFR

2012-07-01

... the trial in obedience to such subpoena, is entitled to mileage between his residence and the place of... civilian by a military court or board which has not express statutory authority to issue such process, such... Regulations. (See 6 Comp. Gen. 712.) (ii) There is no authority for payment by the Government of fees to an...

32 CFR 534.3 - Allowable expenses for witnesses.

Code of Federal Regulations, 2010 CFR

2010-07-01

... the trial in obedience to such subpoena, is entitled to mileage between his residence and the place of... civilian by a military court or board which has not express statutory authority to issue such process, such... Regulations. (See 6 Comp. Gen. 712.) (ii) There is no authority for payment by the Government of fees to an...

32 CFR 534.3 - Allowable expenses for witnesses.

Code of Federal Regulations, 2013 CFR

2013-07-01

... the trial in obedience to such subpoena, is entitled to mileage between his residence and the place of... civilian by a military court or board which has not express statutory authority to issue such process, such... Regulations. (See 6 Comp. Gen. 712.) (ii) There is no authority for payment by the Government of fees to an...

Special Needs. Viewpoints. A Series of Occasional Papers on Basic Education. Issue No. 2.

ERIC Educational Resources Information Center

Adult Literacy and Basic Skills Unit, London (England).

This collection of papers focuses on working with adults who have special needs. In her paper entitled "Literacy and the Visually Handicapped," Janice E. Mason examines ways in which strategies for meeting the needs of visually handicapped persons can be integrated into literacy programs. "Singer and Listener: Basic Education Work…

Assessing the anticancer effects associated with food products and/or nutraceuticals using in vitro and in vivo preclinical development-related pharmacological tests.

USDA-ARS?s Scientific Manuscript database

The current review is part of a special issue entitled “Role of dietary pattern, foods, nutrients and nutraceuticals in supporting cancer prevention and treatment”; it deals with the description of a pharmacological strategy aiming to actually determine the potential contribution of food-related com...

Triple Science GCSEs: Collaborative Approaches. GCSEs in Biology, Chemistry and Physics

ERIC Educational Resources Information Center

Beamish, Val; Rhys, Jenny, Ed.

2007-01-01

Many schools that are preparing to introduce Triple Science GCSEs may find it helpful to collaborate with other schools or other institutions to share expertise and explore how best to deliver the entitlement. This publication looks at some of the issues facing schools in doing this. It focuses on the benefits of collaborative working and the…

Summary of prospective global change impacts on northern U.S. forest ecosystems

Treesearch

Richard A. Birdsey; Robert A. Mickler; John Hom; Linda S. Heath

2000-01-01

In January 1989, the President's Fiscal Year 1990 Budget to the Congress was accompanied by a report entitled, "Our Changing Planet: A U.S. Strategy for Global Change Research" (Committee on Earth Sciences, 1989). The report focused the attention of policy makers on the significant environmental issues arising from natural and human-induced changes in...

Military Famine, Human Rights, and Child Hunger: A Cross-National Analysis, 1990-2000

ERIC Educational Resources Information Center

Jenkins, J. Craig; Scanlan, Stephen J.; Peterson, Lindsey

2007-01-01

Discussions of world hunger have focused on economic growth and international food aid, assuming that food supply is the critical issue. The authors show that food access rooted in social stratification and military power is the central problem. Synthesizing the entitlement and military famine approaches to hunger, the authors examine the effects…

Argumentation and Indigenous Knowledge: Socio-Historical Influences in Contextualizing an Argumentation Model in South African Schools

ERIC Educational Resources Information Center

Gallard Martinez, Alejandro J.

2011-01-01

This forum considers argumentation as a means of science teaching in South African schools, through the integration of indigenous knowledge (IK). It addresses issues raised in Mariana G. Hewson and Meshach B. Ogunniyi's paper entitled: Argumentation-teaching as a method to introduce indigenous knowledge into science classrooms: opportunities and…

What are the implications of the Institute of Medicine report "The future of nursing: leading change, advancing health" for school nursing practice?

PubMed

Sheetz, Anne H

2012-11-01

In 2010, the Robert Wood Johnson Foundation Initiative at the Institute of Medicine issued a comprehensive report entitled, "The future of nursing: leading change, advancing health." The following is a synopsis of the report, including excerpts, recommendations, and a discussion of school nursing implications.

Is Elevating Sir John A. Macdonald Really Worth It? Hitting the Reset Button on Canada's Founding Narrative in the Classroom

ERIC Educational Resources Information Center

Gaudry, Adam

2017-01-01

This special issue of "Canadian Social Studies," entitled "Monumental Mistakes? Confronting Difficult Pasts," has brought together a diverse range of scholars offering insights into discussions regarding removing or altering monuments, buildings, and other reminders of difficult histories. The editors have requested that…

Academic Freedom and Student Grading in Greek Higher Education

ERIC Educational Resources Information Center

Papadimitriou, Antigoni

2011-01-01

The issue of who has the final say on academic standards (grading), academics or managers, has hitherto not arisen in Greece. Professors entitled to research, to teach and to inquire is a freedom expressed by the Greek Constitution. This article presents a contemporary view and raises concerns about the future and the longevity of academic freedom…

Access to Knowledge: The Continuing Agenda for Our Nation's Schools. Revised Edition.

ERIC Educational Resources Information Center

Goodlad, John I., Ed.; Keating, Pamela, Ed.

This book presents a collection of essays by education researchers and practitioners about issues of educational equity and excellence. The authors examine the problem of failure in schools and describe the various curricular and structural factors that block access to an equal and quality education for all students. Chapters are entitled: (1)…

Twilight Musings Concerning the Gamma Doradus Phenomenon

NASA Astrophysics Data System (ADS)

Kaye, A. B.; Zerbi, F. M.

1997-07-01

In this contribution, we intend to address some of the points in the article entitled ``Night Thoughts on Slowly Variable F-Type Stars'' by Gautschy and Loeffler in the Delta Scuti Newsletter, issue 10 (1996). We present these points as direct results of the conference ``A Half-Century of Stellar Pulsation'' at Los Alamos National Laboratory in June 1997.

12 CFR 152.4 - Charter amendments.

Code of Federal Regulations, 2012 CFR

2012-01-01

... this part, shall be approved at the time of adoption, if adopted without change and filed with the OCC... of each such class]. The shares may be issued from time to time as authorized by the board of...) shall entitle the holders of any class of a series of capital stock to vote as a separate class or...

Food and Population: A Global Concern [and] The Paradoxes of World Hunger.

ERIC Educational Resources Information Center

Murphy, Elaine M.

1984-01-01

Student and teacher materials are provided for a secondary unit on world hunger. The student materials are contained in a module entitled "Food and Population: A Global Concern," distributed with the newsletter "Interchange." The teacher materials are contained in the issue of the newsletter itself, subtitled "The Paradoxes of World Hunger." A…

Response to Pienemann's Critique of Zhang and Lantolf (2015)

ERIC Educational Resources Information Center

Lantolf, James P.; Zhang, Xian

2015-01-01

We respond here to Pienemann's critique of our study that appeared earlier this year in the Language Learning Special Issue entitled "Orders and Sequences in the Acquisition of L2 Morphosyntax, 40 Years On" and guest edited by Jan Hulstijn, Rod Ellis, and Søren Eskildsen. Pienemann objected to our claim that the Teachability Hypothesis…

Media and Violence. Part Two: Searching for Solutions. Media & Values 63.

ERIC Educational Resources Information Center

Silver, Rosalind, Ed.

1993-01-01

This issue of "Media & Values" explores the influence of mass media and violence in society. The essays present various interpretations of that influence and the implications for the society. A special section entitled "Forum: Searching for Solutions" contains 5 articles. Articles include: (1) "20 Ways to Create a Culture of Caring" (Jay Dover);…

Stability Analysis of Finite Difference Approximations to Hyperbolic Systems,and Problems in Applied and Computational Matrix and Operator Theory

DTIC Science & Technology

1990-12-07

Fundaqao Calouste Gulbenkian, Instituto Gulbenkian de Ci~ncia, Centro de C6lculo Cientifico , Coimbra, 1973. 28, Dirac, P. A. M., Spinors in Hilbert Space...Office of Scientific Research grants 1965 Mathematical Association of America Editorial Prize for the article entitled: "Linear Transformations on...matrices" 1966 L.R. Ford Memorial Prize awarded by the Mathematical Association of America for the article , "Permanents" 1989 Outstanding Computer

High-Performance Computing and Four-Dimensional Data Assimilation: The Impact on Future and Current Problems

NASA Technical Reports Server (NTRS)

Makivic, Miloje S.

1996-01-01

This is the final technical report for the project entitled: "High-Performance Computing and Four-Dimensional Data Assimilation: The Impact on Future and Current Problems", funded at NPAC by the DAO at NASA/GSFC. First, the motivation for the project is given in the introductory section, followed by the executive summary of major accomplishments and the list of project-related publications. Detailed analysis and description of research results is given in subsequent chapters and in the Appendix.

Enhancing the Attractiveness of Alcohol Education Via a Microcomputer Program.

ERIC Educational Resources Information Center

Meier, Scott T.

Getting students' attention is one of the most difficult problems for counselors who conduct alcohol education programs in high schools or colleges. A computer-aided instruction program using microcomputers for alcohol education was developed entitled "If You Drink: An Alcohol Education Program" (IYD). The IYD program consists of five modules: the…

The Revolution in Print Technology. Text & Readers Programme, Technical Report #1.

ERIC Educational Resources Information Center

Macdonald-Ross, Michael

The two papers presented in this document discuss aspects of the computer revolution and its effects on the production of print materials. The papers are addressed to readers who are educators rather than technologists. The first article, entitled "Print," interprets that term broadly to include text development and production, and…

Computer Assisted Instruction in Teacher Education: A Full Length Course.

ERIC Educational Resources Information Center

Cartwright, G. Phillip

Pennsylvania State University has developed, evaluated, and implemented a series of modules and an entire three-credit teacher education course which is offered completely by microcomputer. The course is entitled "Educating Special Learners." The modules use the Apple II series and the IBM PC series. Evaluation of the course, based on…

Alexander Meets Michotte: A Simulation Tool Based on Pattern Programming and Phenomenology

ERIC Educational Resources Information Center

Basawapatna, Ashok

2016-01-01

Simulation and modeling activities, a key point of computational thinking, are currently not being integrated into the science classroom. This paper describes a new visual programming tool entitled the Simulation Creation Toolkit. The Simulation Creation Toolkit is a high level pattern-based phenomenological approach to bringing rapid simulation…

75 FR 1584 - Submission for OMB Review; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-12

... Food Service Program Claim for Reimbursement Form is used to collect meal and cost data from sponsors to determine the reimbursement entitlement for meals served. The form is sent to the Food and... payment system computes earnings to date and the number of meals to date and generates payments for the...

Development and Evaluation of the SUMIT Microcomputer Module Entitled 'Predator Functional Response'.

ERIC Educational Resources Information Center

Shaltz, Mark B.

An experiment was conducted that compared the teaching effectiveness of a computer assisted instructional module and a lecture-discussion. The module, Predator Functional Response (PFR), was developed as part of the SUMIT (Single-concept User-adaptable Microcomputer-based Instructional Technique) project. A class of 30 students was randomly…

5 CFR 532.503 - Overtime pay.

Code of Federal Regulations, 2011 CFR

2011-01-01

... shall be entitled to overtime pay computed on the average rate of basic pay for all regularly scheduled... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Overtime pay. 532.503 Section 532.503... Pay and Differentials § 532.503 Overtime pay. (a)(1) Employees who are exempt from the overtime pay...

A Course Which Used Programming to Aid Learning Various Mathematical Concepts.

ERIC Educational Resources Information Center

Day, Jane M.

A three unit mathematics course entitled Introduction to Computing evaluated the effectiveness of programing as an aid to learning math concepts and to developing student self-reliance. Sixteen students enrolled in the course at the College of Notre Dame in Belmont, California; one terminal was available, connected to the Stanford Computation…

10 CFR 13.27 - Computation of time.

Code of Federal Regulations, 2010 CFR

2010-01-01

...; and (2) By 11:59 p.m. Eastern Time for a document served by the E-Filing system. [72 FR 49153, Aug. 28... the calculation of additional days when a participant is not entitled to receive an entire filing... same filing and service method, the number of days for service will be determined by the presiding...

10 CFR 2.306 - Computation of time.

Code of Federal Regulations, 2010 CFR

2010-01-01

...:59 p.m. Eastern Time for a document served by the E-Filing system. [72 FR 49151, Aug. 28, 2007] ... the calculation of additional days when a participant is not entitled to receive an entire filing... filing and service method, the number of days for service will be determined by the presiding officer...

The development of a specialized processor for a space-based multispectral earth imager

NASA Astrophysics Data System (ADS)

Khedr, Mostafa E.

2008-10-01

This work was done in the Department of Computer Engineering, Lvov Polytechnic National University, Lvov, Ukraine, as a thesis entitled "Space Imager Computer System for Raw Video Data Processing" [1]. This work describes the synthesis and practical implementation of a specialized computer system for raw data control and processing onboard a satellite MultiSpectral earth imager. This computer system is intended for satellites with resolution in the range of one meter with 12-bit precession. The design is based mostly on general off-the-shelf components such as (FPGAs) plus custom designed software for interfacing with PC and test equipment. The designed system was successfully manufactured and now fully functioning in orbit.

Light scattering by planetary-regolith analog samples: computational results

NASA Astrophysics Data System (ADS)

Väisänen, Timo; Markkanen, Johannes; Hadamcik, Edith; Levasseur-Regourd, Anny-Chantal; Lasue, Jeremie; Blum, Jürgen; Penttilä, Antti; Muinonen, Karri

2017-04-01

We compute light scattering by a planetary-regolith analog surface. The corresponding experimental work is from Hadamcik et al. [1] with the PROGRA2-surf [2] device measuring the polarization of dust particles. The analog samples are low density (volume fraction 0.15 ± 0.03) agglomerates produced by random ballistic deposition of almost equisized silica spheres (refractive index n=1.5 and diameter 1.45 ± 0.06 µm). Computations are carried out with the recently developed codes entitled Radiative Transfer with Reciprocal Transactions (R2T2) and Radiative Transfer Coherent Backscattering with incoherent interactions (RT-CB-ic). Both codes incorporate the so-called incoherent treatment which enhances the applicability of the radiative transfer as shown by Muinonen et al. [3]. As a preliminary result, we have computed scattering from a large spherical medium with the RT-CB-ic using equal-sized particles with diameters of 1.45 microns. The preliminary results have shown that the qualitative characteristics are similar for the computed and measured intensity and polarization curves but that there are still deviations between the characteristics. We plan to remove the deviations by incorporating a size distribution of particles (1.45 ± 0.02 microns) and detailed information about the volume density profile within the analog surface. Acknowledgments: We acknowledge the ERC Advanced Grant no. 320773 entitled Scattering and Absorption of Electromagnetic Waves in Particulate Media (SAEMPL). Computational resources were provided by CSC - IT Centre for Science Ltd, Finland. References: [1] Hadamcik E. et al. (2007), JQSRT, 106, 74-89 [2] Levasseur-Regourd A.C. et al. (2015), Polarimetry of stars and planetary systems, CUP, 61-80 [3] Muinonen K. et al. (2016), extended abstract for EMTS.

Seven Experiment Designs Addressing Problems of Safety and Capacity on Two-Lane Rural Highways : Volume 7. Experimental Design to Develop and Evaluate Measures for Reducing the Effects of Roadside Friction on Traffic Flow

DOT National Transportation Integrated Search

1994-04-01

This operational test case study is one of six performed in response to a Volpe National Transportation Systems Center technical task directive (TTD) to Science Applications International Corporation (SAIC) entitled, "IVHS Institutional Issues and Ca...

Seven Experiment Designs Addressing Problems of Safety and Capacity on Two-Lane Rural Highways : Volume 4. Experimental Design to Develop and Evaluate Remedial Aids to Urban Drivers of Slow Moving Vehicles on a Grade

DOT National Transportation Integrated Search

1994-04-01

This operational test case study is one of six performed in response to a Volpe National Transportation Systems Center technical task directive (TTD) to Science Applications International Corporation (SAIC) entitled, IVHS Institutional Issues and ...

Feminist Perspectives on TANF Reauthorization: An Introduction to Key Issues for the Future of Welfare Reform. Briefing Paper.

ERIC Educational Resources Information Center

Peterson, Janice

Current debates about welfare reform center on the upcoming reauthorization of the Temporary Assistance for Needy Families (TANF) legislation. The provisions of TANF include the elimination of the entitlement to cash assistance, block grant funding to the states, mandatory work requirements, sanctions, a 5-year limit on cash assistance, and…

77 FR 60142 - Notice of Lodging of Proposed Consent Decree Under the Clean Air Act

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-02

... District Court for the District of Arizona in the lawsuit entitled United States v. CEMEX Construction... resolves the civil claims alleged in the complaint and in the Finding and Notice of Violation issued to the... Division, and should refer to United States v. CEMEX Construction Materials South, LLC, D.J. Ref. No. 90-5...

21 CFR 1305.04 - Persons entitled to order Schedule I and II controlled substances.

Code of Federal Regulations, 2011 CFR

2011-04-01

... to order Schedule I and II controlled substances. (a) Only persons who are registered with DEA under... are registered with DEA under section 1008 of the Act (21 U.S.C. 958) to export these substances may obtain and use DEA Form 222 (order forms) or issue electronic orders for these substances. Persons not...

21 CFR 1305.04 - Persons entitled to order Schedule I and II controlled substances.

Code of Federal Regulations, 2010 CFR

2010-04-01

... to order Schedule I and II controlled substances. (a) Only persons who are registered with DEA under... are registered with DEA under section 1008 of the Act (21 U.S.C. 958) to export these substances may obtain and use DEA Form 222 (order forms) or issue electronic orders for these substances. Persons not...

Multi-Scale Sizing of Lightweight Multifunctional Spacecraft Structural Components

NASA Technical Reports Server (NTRS)

Bednarcyk, Brett A.

2005-01-01

This document is the final report for the project entitled, "Multi-Scale Sizing of Lightweight Multifunctional Spacecraft Structural Components," funded under the NRA entitled "Cross-Enterprise Technology Development Program" issued by the NASA Office of Space Science in 2000. The project was funded in 2001, and spanned a four year period from March, 2001 to February, 2005. Through enhancements to and synthesis of unique, state of the art structural mechanics and micromechanics analysis software, a new multi-scale tool has been developed that enables design, analysis, and sizing of advance lightweight composite and smart materials and structures from the full vehicle, to the stiffened structure, to the micro (fiber and matrix) scales. The new software tool has broad, cross-cutting value to current and future NASA missions that will rely on advanced composite and smart materials and structures.

Unheard Voices: The Need for HIV Research and Prevention Priorities for YMSM in the Global Context.

PubMed

Hall, Casey D; Murdock, Daniel; Nehl, Eric J; Wong, Frank Y

2016-06-01

This commentary considers the AIDS Education and Prevention special issue (volume 28, number 3) entitled "Behavioral HIV Prevention Interventions for Diverse Young Men Who Have Sex with Men (MSM)." The research presented in this special issue highlights the importance of addressing sub-populations of young MSM in order to better understand the unique realities and risk-factors affecting HIV epidemics and intervention needs. Here, we focus on several broad topics raised in this special issue and comment on their implications for HIV research and practice targeting young MSM in low- and middle-income countries. We consider issues relevant to reaching hidden populations, tailoring interventions, and integrating new communications and bio-medical technologies in research and practice in low-resource settings.

20 CFR 404.141 - How we credit quarters of coverage for calendar years before 1978.

Code of Federal Regulations, 2010 CFR

2010-04-01

... FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Insured Status and Quarters of Coverage... (or might not meet as early in the year as otherwise possible) the requirements to be fully or currently insured, to be entitled to a computation or recomputation of your primary insurance amount, or to...

Accelerated Mathematics and High-Ability Students' Math Achievement in Grades Three and Four

ERIC Educational Resources Information Center

Stanley, Ashley M.

2011-01-01

The purpose of this study was to explore the relationship between the use of a computer-managed integrated learning system entitled Accelerated Math (AM) as a supplement to traditional mathematics instruction on achievement as measured by TerraNova achievement tests of third and fourth grade high-ability students. Gender, socioeconomic status, and…

The Development and Use of a Language Arts Computer Software Program Appropriate for Special Needs Children.

ERIC Educational Resources Information Center

Murphy, Jo-Anne

For a school year, a language arts software program was used to help special needs children in Marblehead, Massachusetts who represented a range of learning disabilities and emotional, behavioral and physical disorders of varying degrees of severity. The program had three major components, entitled "Nouns,""Verbs," and "Adjectives." These…

Assessment of the Effectiveness of Internet-Based Distance Learning through the VClass e-Education Platform

ERIC Educational Resources Information Center

Pukkaew, Chadchadaporn

2013-01-01

This study assesses the effectiveness of internet-based distance learning (IBDL) through the VClass live e-education platform. The research examines (1) the effectiveness of IBDL for regular and distance students and (2) the distance students' experience of VClass in the IBDL course entitled Computer Programming 1. The study employed the common…

Decreasing Excessive Media Usage while Increasing Physical Activity: A Single-Subject Research Study

ERIC Educational Resources Information Center

Larwin, Karen H.; Larwin, David A.

2008-01-01

The Kaiser Family Foundation released a report entitled "Kids and Media Use" in the United States that concluded that children's use of media--including television, computers, Internet, video games, and phones--may be one of the primary contributor's to the poor fitness and obesity of many of today's adolescents. The present study examines the…

Scientific American Frontiers Teaching Guides for Shows 701-705, October 1996-April 1997.

ERIC Educational Resources Information Center

Connecticut Public Television, Hartford.

These teaching guides are meant to supplement the seventh season (1996-97) of the PBS Series "Scientific American Frontiers". Episode 701 is entitled "Inventing the Future: A Tour of the MIT Media Lab" and the teaching guide contains information and activities on a virtual pet dog, computers of the future, a smart car designed…

26 CFR 1.668(b)-2A - Special rules applicable to section 668.

Code of Federal Regulations, 2010 CFR

2010-04-01

... accumulation distribution. To compute A's tax under the exact method for 1974 on the $10,000 from the 1980... (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Treatment of Excess Distributions of Trusts Applicable to... section 141 for such calendar year, and (6) Was entitled to the personal exemption under section 151 or...

A Class at Mount Holyoke College Uses "Frankenstein" as a Tool for Teaching Student Multimedia Techniques.

ERIC Educational Resources Information Center

Gose, Ben

1997-01-01

A Mount Holyoke College (Massachusetts) class on computer applications in history and the humanities, entitled "Frankenstein Meets Multimedia," uses topics from the 1818 novel as the basis for students to develop multimedia compact disks about it. The novel is used because its author was heavily influenced by the philosophy of the…

Outstanding Research Issues in Systematic Technology Prioritization for New Space Missions: Workshop Proceedings

NASA Technical Reports Server (NTRS)

Weisbin, C. R. (Editor)

2004-01-01

A workshop entitled, "Outstanding Research Issues in Systematic Technology Prioritization for New Space Missions," was convened on April 21-22, 2004 in San Diego, California to review the status of methods for objective resource allocation, to discuss the research barriers remaining, and to formulate recommendations for future development and application. The workshop explored the state-of-the-art in decision analysis in the context of being able to objectively allocate constrained technical resources to enable future space missions and optimize science return. This article summarizes the highlights of the meeting results.

Knowledge based systems: A critical survey of major concepts, issues and techniques. Visuals

NASA Technical Reports Server (NTRS)

Dominick, Wayne D. (Editor); Kavi, Srinu

1984-01-01

This Working Paper Series entry represents a collection of presentation visuals associated with the companion report entitled, Knowledge Based Systems: A Critical Survey of Major Concepts, Issues, and Techniques, USL/DBMS NASA/RECON Working Paper Series report number DBMS.NASA/RECON-9. The objectives of the report are to: examine various techniques used to build the KBS; to examine at least one KBS in detail, i.e., a case study; to list and identify limitations and problems with the KBS; to suggest future areas of research; and to provide extensive reference materials.

Teaching Research Integrity and Bioethics to Science Undergraduates

PubMed Central

2005-01-01

Undergraduate students in the Department of Biomedical Sciences at the University of South Alabama, Mobile, are required to take a course entitled “Issues in Biomedical Sciences,” designed to increase students' awareness about bioethical questions and issues concerning research integrity. This paper describes the main features of this course and summarizes the results of a survey designed to evaluate the students' perceptions about the course. A summary of this study was presented at the 2002 Conference on Research Integrity in Potomac, MD, sponsored by the Office of Research Integrity of the National Institutes of Health. PMID:16341260

Towards the formal specification of the requirements and design of a processor interface unit

NASA Technical Reports Server (NTRS)

Fura, David A.; Windley, Phillip J.; Cohen, Gerald C.

1993-01-01

Work to formally specify the requirements and design of a Processor Interface Unit (PIU), a single-chip subsystem providing memory interface, bus interface, and additional support services for a commercial microprocessor within a fault-tolerant computer system, is described. This system, the Fault-Tolerant Embedded Processor (FTEP), is targeted towards applications in avionics and space requiring extremely high levels of mission reliability, extended maintenance free operation, or both. The approaches that were developed for modeling the PIU requirements and for composition of the PIU subcomponents at high levels of abstraction are described. These approaches were used to specify and verify a nontrivial subset of the PIU behavior. The PIU specification in Higher Order Logic (HOL) is documented in a companion NASA contractor report entitled 'Towards the Formal Specification of the Requirements and Design of a Processor Interfacs Unit - HOL Listings.' The subsequent verification approach and HOL listings are documented in NASA contractor report entitled 'Towards the Formal Verification of the Requirements and Design of a Processor Interface Unit' and NASA contractor report entitled 'Towards the Formal Verification of the Requirements and Design of a Processor Interface Unit - HOL Listings.'

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bailey, David H.

In a previous humorous note entitled 'Twelve Ways to Fool the Masses,' I outlined twelve common ways in which performance figures for technical computer systems can be distorted. In this paper and accompanying conference talk, I give a reprise of these twelve 'methods' and give some actual examples that have appeared in peer-reviewed literature in years past. I then propose guidelines for reporting performance, the adoption of which would raise the level of professionalism and reduce the level of confusion, not only in the world of device simulation but also in the larger arena of technical computing.

A short recollection on the paper entitled "A common sense approach to peak picking in two-, three-, and four-dimensional spectra using automatic computer analysis of contour diagrams" by D.S. Garrett, R. Powers, A.M. Gronenborn, and G.M. Clore [J. Magn. Reson. 95 (1991) 214-220].

PubMed

Garrett, Daniel S; Gronenborn, Angela M; Clore, G Marius

2011-12-01

The Contour Approach to Peak Picking was developed to aid in the analysis and interpretation and of multidimensional NMR spectra of large biomolecules. In essence, it comprises an interactive graphics software tool to computationally select resonance positions in heteronuclear, 3- and 4D spectra. Copyright © 2011. Published by Elsevier Inc.

Nicotinic alteration of decision-making.

PubMed

Naudé, Jérémie; Dongelmans, Malou; Faure, Philippe

2015-09-01

Addiction to nicotine is characterized by impulses, urges and lack of self-control towards cigarettes. A key element in the process of addiction is the development of habits oriented towards nicotine consumption that surpass flexible systems as a consequence of a gradual adaptation to chronic drug exposure. However, the long-term effects of nicotine on brain circuits also induce wide changes in decision-making processes, affecting behaviors unrelated to cigarettes. This review aims at providing an update on the implications of nicotine on general decision-making processes, with an emphasis on impulsivity and risk-taking. As impulsivity is a rather ambiguous behavioral trait, we build on economic and normative theories to better characterize these nicotine-induced alterations in decision-making. Nonetheless, experimental data are sparse and often contradictory. We will discuss how the latest findings on the neurobiological basis of choice behavior may help disentangling these issues. We focus on the role of nicotine acetylcholine receptors and their different subunits, and on the spatio-temporal dynamics (i.e. diversity of the neural circuits, short- and long-term effects) of both endogenous acetylcholine and nicotine action. Finally, we try to link these neurobiological results with neuro-computational models of attention, valuation and action, and of the role of acetylcholine in these decision processes. This article is part of the Special Issue entitled 'The Nicotinic Acetylcholine Receptor: From Molecular Biology to Cognition'. Copyright © 2014 Elsevier Ltd. All rights reserved.

Income-related inequity in the use of GP services by children: a comparison of Ireland and Scotland.

PubMed

Layte, Richard; Nolan, Anne

2015-06-01

Equity of access to health care is a key component of national and international health policy, with most countries subscribing to the principle that health care should be allocated on the basis of need, rather than ability to pay or other criteria. The issue of health care entitlements for children is particularly pertinent given the strong causal links that have been demonstrated between eligibility for free care, utilisation and health outcomes. The Irish health care system is unusual in requiring the majority of the population to pay the full out-of-pocket cost of GP care. In contrast, all Scottish residents are entitled to free GP care at the point of use. This difference in public health care entitlements between Ireland and Scotland allows us to examine the impact of differences in financing structures on equity in GP care. In this paper, we use data from two nationally representative surveys of children in Ireland and Scotland to examine the degree of income-related inequity in the utilisation of GP services in both countries. We find that while the distribution of GP care is significantly pro-poor in Ireland, even after adjustment for health need, there is little or no significant inequity in GP utilisation among Scottish children. However, focusing just on children who pay the full price of GP care in Ireland, we find some evidence for a significant pro-rich distribution of GP visits. These results reflect the particular structure of health care entitlements that exist in two systems.

Molecular dynamics simulations of biological membranes and membrane proteins using enhanced conformational sampling algorithms.

PubMed

Mori, Takaharu; Miyashita, Naoyuki; Im, Wonpil; Feig, Michael; Sugita, Yuji

2016-07-01

This paper reviews various enhanced conformational sampling methods and explicit/implicit solvent/membrane models, as well as their recent applications to the exploration of the structure and dynamics of membranes and membrane proteins. Molecular dynamics simulations have become an essential tool to investigate biological problems, and their success relies on proper molecular models together with efficient conformational sampling methods. The implicit representation of solvent/membrane environments is reasonable approximation to the explicit all-atom models, considering the balance between computational cost and simulation accuracy. Implicit models can be easily combined with replica-exchange molecular dynamics methods to explore a wider conformational space of a protein. Other molecular models and enhanced conformational sampling methods are also briefly discussed. As application examples, we introduce recent simulation studies of glycophorin A, phospholamban, amyloid precursor protein, and mixed lipid bilayers and discuss the accuracy and efficiency of each simulation model and method. This article is part of a Special Issue entitled: Membrane Proteins edited by J.C. Gumbart and Sergei Noskov. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.

A tutorial for software development in quantitative proteomics using PSI standard formats☆

PubMed Central

Gonzalez-Galarza, Faviel F.; Qi, Da; Fan, Jun; Bessant, Conrad; Jones, Andrew R.

2014-01-01

The Human Proteome Organisation — Proteomics Standards Initiative (HUPO-PSI) has been working for ten years on the development of standardised formats that facilitate data sharing and public database deposition. In this article, we review three HUPO-PSI data standards — mzML, mzIdentML and mzQuantML, which can be used to design a complete quantitative analysis pipeline in mass spectrometry (MS)-based proteomics. In this tutorial, we briefly describe the content of each data model, sufficient for bioinformaticians to devise proteomics software. We also provide guidance on the use of recently released application programming interfaces (APIs) developed in Java for each of these standards, which makes it straightforward to read and write files of any size. We have produced a set of example Java classes and a basic graphical user interface to demonstrate how to use the most important parts of the PSI standards, available from http://code.google.com/p/psi-standard-formats-tutorial. This article is part of a Special Issue entitled: Computational Proteomics in the Post-Identification Era. Guest Editors: Martin Eisenacher and Christian Stephan. PMID:23584085

The amino acid's backup bone - storage solutions for proteomics facilities.

PubMed

Meckel, Hagen; Stephan, Christian; Bunse, Christian; Krafzik, Michael; Reher, Christopher; Kohl, Michael; Meyer, Helmut Erich; Eisenacher, Martin

2014-01-01

Proteomics methods, especially high-throughput mass spectrometry analysis have been continually developed and improved over the years. The analysis of complex biological samples produces large volumes of raw data. Data storage and recovery management pose substantial challenges to biomedical or proteomic facilities regarding backup and archiving concepts as well as hardware requirements. In this article we describe differences between the terms backup and archive with regard to manual and automatic approaches. We also introduce different storage concepts and technologies from transportable media to professional solutions such as redundant array of independent disks (RAID) systems, network attached storages (NAS) and storage area network (SAN). Moreover, we present a software solution, which we developed for the purpose of long-term preservation of large mass spectrometry raw data files on an object storage device (OSD) archiving system. Finally, advantages, disadvantages, and experiences from routine operations of the presented concepts and technologies are evaluated and discussed. This article is part of a Special Issue entitled: Computational Proteomics in the Post-Identification Era. Guest Editors: Martin Eisenacher and Christian Stephan. Copyright © 2013. Published by Elsevier B.V.

Structure-activity relationships in carbohydrates revealed by their hydration.

PubMed

Maugeri, Laura; Busch, Sebastian; McLain, Sylvia E; Pardo, Luis Carlos; Bruni, Fabio; Ricci, Maria Antonietta

2017-06-01

One of the more intriguing aspects of carbohydrate chemistry is that despite having very similar molecular structures, sugars have very different properties. For instance, there is a sensible difference in sweet taste between glucose and trehalose, even though trehalose is a disaccharide that comprised two glucose units, suggesting a different ability of these two carbohydrates to bind to sweet receptors. Here we have looked at the hydration of specific sites and at the three-dimensional configuration of water molecules around three carbohydrates (glucose, cellobiose, and trehalose), combining neutron diffraction data with computer modelling. Results indicate that identical chemical groups can have radically different hydration patterns depending on their location on a given molecule. These differences can be linked with the specific activity of glucose, cellobiose, and trehalose as a sweet substance, as building block of cellulose fiber, and as a bioprotective agent, respectively. This article is part of a Special Issue entitled "Recent Advances in Bionanomaterials" Guest Editors: Dr. Marie-Louise Saboungi and Dr. Samuel D. Bader. Copyright © 2016 Elsevier B.V. All rights reserved.

Teacher Resource Book for Population Pressure in Indonesia, Problems of Industrialization in Eurasia, Power Blocs in Eurasia. Man on the Earth Series.

ERIC Educational Resources Information Center

Gunn, Angus

This teacher's resource book is a guide to three intermediate texts about Eurasia entitled Population Pressure in Indonesia, Problems of Industrialization in Eurasia, and Power Blocs in Eurasia. The texts are part of the series, Man on the Earth, which probes broad-based issues confronting mankind. The resource book distinguishes 18 major concepts…

77 FR 70168 - Guidance for Industry and Food and Drug Administration Staff; The Content of Investigational...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-23

...The Food and Drug Administration (FDA) is announcing the availability of the guidance entitled ``The Content of Investigational Device Exemption (IDE) and Premarket Approval (PMA) Applications for Artificial Pancreas Device Systems.'' FDA is issuing this guidance to inform industry and Agency staff of its recommendations for analytical and clinical performance studies to support premarket submissions for artificial pancreas systems.

A Misleading Review of Response Bias: Comment on McGrath, Mitchell, Kim, and Hough (2010)

ERIC Educational Resources Information Center

Rohling, Martin L.; Larrabee, Glenn J.; Greiffenstein, Manfred F.; Ben-Porath, Yossef S.; Lees-Haley, Paul; Green, Paul; Greve, Kevin W.

2011-01-01

In the May 2010 issue of "Psychological Bulletin," R. E. McGrath, M. Mitchell, B. H. Kim, and L. Hough published an article entitled "Evidence for Response Bias as a Source of Error Variance in Applied Assessment" (pp. 450-470). They argued that response bias indicators used in a variety of settings typically have insufficient data to support such…

PTC'85: Toward a Digital World. Telecommunications for Pacific Development. Proceedings of the Annual Conference of the Pacific Telecommunications Council (7th, Honolulu, HI, January 13-16, 1985).

ERIC Educational Resources Information Center

Wedemeyer, Dan J., Ed.

More than 60 papers in this conference proceedings address telecommunications issues in the Pacific region, specifically focusing on the development, use, implementation, and management of new digital communications channels. Following a keynote address on the political and economic realities in the Pacific, entitled "Progress Report on the…

Workshop on Functional Aspects of Regeneration of the Boreal Forest in the Context of Sustainable Forest Management

Treesearch

Christian Messier; John Zasada; David Greene

1999-01-01

The three review papers presented in this issue of the Canadian Journal of Forest Research follow a 1-day workshop that was held in Montreal in early January 1997 entitled Functional Aspects of Regeneration In the Boreal Forest in the Context of Sustainable Forest Management. This workshop was held as part of the regeneration working group of Canada...

Environmental Studies: A High School Course for Each Citizen, of Each Town, in South Carolina, U.S.A.

ERIC Educational Resources Information Center

Alsbrooks, Ann; And Others

This is a complete environmental studies course for high schools. It may be used as a year-long elective, a semester course, or infused by individual units into science, social studies, health, or other courses. The course is composed of thirteen separate units entitled: (1) Investigating Environmental Problems and Issues; (2) Energy; (3) Water;…

ComplexQuant: high-throughput computational pipeline for the global quantitative analysis of endogenous soluble protein complexes using high resolution protein HPLC and precision label-free LC/MS/MS.

PubMed

Wan, Cuihong; Liu, Jian; Fong, Vincent; Lugowski, Andrew; Stoilova, Snejana; Bethune-Waddell, Dylan; Borgeson, Blake; Havugimana, Pierre C; Marcotte, Edward M; Emili, Andrew

2013-04-09

The experimental isolation and characterization of stable multi-protein complexes are essential to understanding the molecular systems biology of a cell. To this end, we have developed a high-throughput proteomic platform for the systematic identification of native protein complexes based on extensive fractionation of soluble protein extracts by multi-bed ion exchange high performance liquid chromatography (IEX-HPLC) combined with exhaustive label-free LC/MS/MS shotgun profiling. To support these studies, we have built a companion data analysis software pipeline, termed ComplexQuant. Proteins present in the hundreds of fractions typically collected per experiment are first identified by exhaustively interrogating MS/MS spectra using multiple database search engines within an integrative probabilistic framework, while accounting for possible post-translation modifications. Protein abundance is then measured across the fractions based on normalized total spectral counts and precursor ion intensities using a dedicated tool, PepQuant. This analysis allows co-complex membership to be inferred based on the similarity of extracted protein co-elution profiles. Each computational step has been optimized for processing large-scale biochemical fractionation datasets, and the reliability of the integrated pipeline has been benchmarked extensively. This article is part of a Special Issue entitled: From protein structures to clinical applications. Copyright © 2012 Elsevier B.V. All rights reserved.

Academic Entitlement and Academic Performance in Graduating Pharmacy Students

PubMed Central

Barclay, Sean M.; Stolte, Scott K.

2014-01-01

Objectives. To determine a measurable definition of academic entitlement, measure academic entitlement in graduating doctor of pharmacy (PharmD) students, and compare the academic performance between students identified as more or less academically entitled. Methods. Graduating students at a private health sciences institution were asked to complete an electronic survey instrument that included demographic data, academic performance, and 2 validated academic entitlement instruments. Results. One hundred forty-one of 243 students completed the survey instrument. Fourteen (10%) students scored greater than the median total points possible on 1 or both of the academic entitlement instruments and were categorized as more academically entitled. Less academically entitled students required fewer reassessments and less remediation than more academically entitled students. The highest scoring academic entitlement items related to student perception of what professors should do for them. Conclusion. Graduating pharmacy students with lower levels of academic entitlement were more academically successful than more academically entitled students. Moving from an expert opinion approach to evidence-based decision-making in the area of academic entitlement will allow pharmacy educators to identify interventions that will decrease academic entitlement and increase academic success in pharmacy students. PMID:25147388

Preface to "Insights into the Earth's Deep Lithosphere"

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pasyanos, M E

Dear Readers: I am pleased to present a special issue of Tectonophysics entitled 'Insights into the Earth's Deep Lithosphere.' This compilation sought to capture the flavor of the increasing number of studies that are emerging to investigate the complex lithospheric structure of the earth. This issue evolved out of a Fall 2007 AGU special session entitled 'Understanding the Earth's Deep Lithosphere' that I organized with Irina Artemieva from the University of Copenhagen. For that session, we solicited talks that discussed the increasing number of methods that have surfaced to study various aspects of the earth's deep lithosphere. These methods includemore » seismic, gravity, thermal, geochemical, and various combinations of these methods. The quality of the presentations (2 oral sessions with 16 talks and 23 associated poster presentations) was such that we felt that the emerging topic deserved a dedicated forum to address these questions in greater detail. The availability of new data sets has also improved the number and quality of lithospheric studies. With many new studies and methodologies, a better understanding of both continental and oceanic lithospheres is starting to emerge. Questions remain about the thickness and evolution of the lithosphere, the presence of lithospheric keels, the density and anisotropy of lithospheric roots, mechanisms of lithospheric thinning, and differences between mechanical, thermal and chemical boundary layers. While we did not get contributions on the full gamut of methods and regions, a lot of ground was covered in this issue's manuscripts. Like any collection of papers on the deep lithosphere, the topics are quite varied in methodology, geographic location, and what aspect of the lithosphere being studied. Still, the results highlight the rewarding aspects of earth structure, history, and evolution that can be gleaned. A brief synopsis of the papers contained in this issue is given.« less

48 CFR 1852.213-70 - Offeror Representations and Certifications-Other Than Commercial Items.

Code of Federal Regulations, 2013 CFR

2013-10-01

...: “Limited rights data” and “Restricted computer software” are defined in the contract clause entitled...) Service-disabled veteran means a veteran, as defined in 38 U.S.C. 101(2), with a disability that is service-connected, as defined in 38 U.S.C. 101(16). “Small business concern” means a concern, including...

48 CFR 1852.213-70 - Offeror Representations and Certifications-Other Than Commercial Items.

Code of Federal Regulations, 2014 CFR

2014-10-01

...: “Limited rights data” and “Restricted computer software” are defined in the contract clause entitled...) Service-disabled veteran means a veteran, as defined in 38 U.S.C. 101(2), with a disability that is service-connected, as defined in 38 U.S.C. 101(16). “Small business concern” means a concern, including...

48 CFR 1852.213-70 - Offeror Representations and Certifications-Other Than Commercial Items.

Code of Federal Regulations, 2011 CFR

2011-10-01

...: “Limited rights data” and “Restricted computer software” are defined in the contract clause entitled...) Service-disabled veteran means a veteran, as defined in 38 U.S.C. 101(2), with a disability that is service-connected, as defined in 38 U.S.C. 101(16). “Small business concern” means a concern, including...

48 CFR 1852.213-70 - Offeror Representations and Certifications-Other Than Commercial Items.

Code of Federal Regulations, 2012 CFR

2012-10-01

...: “Limited rights data” and “Restricted computer software” are defined in the contract clause entitled...) Service-disabled veteran means a veteran, as defined in 38 U.S.C. 101(2), with a disability that is service-connected, as defined in 38 U.S.C. 101(16). “Small business concern” means a concern, including...

20 CFR 404.213 - Computation where you are eligible for a pension based on your noncovered employment.

Code of Federal Regulations, 2010 CFR

2010-04-01

... pension based on your noncovered employment. 404.213 Section 404.213 Employees' Benefits SOCIAL SECURITY... you are eligible for a pension based on your noncovered employment. (a) When applicable. Except as... entitled to a monthly pension(s) for which you first became eligible after 1985 based in whole or part on...

Fifth SIAM conference on geometric design 97: Final program and abstracts. Final technical report

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1997-12-31

The meeting was divided into the following sessions: (1) CAD/CAM; (2) Curve/Surface Design; (3) Geometric Algorithms; (4) Multiresolution Methods; (5) Robotics; (6) Solid Modeling; and (7) Visualization. This report contains the abstracts of papers presented at the meeting. Proceding the conference there was a short course entitled ``Wavelets for Geometric Modeling and Computer Graphics``.

Recent advances in QM/MM free energy calculations using reference potentials.

PubMed

Duarte, Fernanda; Amrein, Beat A; Blaha-Nelson, David; Kamerlin, Shina C L

2015-05-01

Recent years have seen enormous progress in the development of methods for modeling (bio)molecular systems. This has allowed for the simulation of ever larger and more complex systems. However, as such complexity increases, the requirements needed for these models to be accurate and physically meaningful become more and more difficult to fulfill. The use of simplified models to describe complex biological systems has long been shown to be an effective way to overcome some of the limitations associated with this computational cost in a rational way. Hybrid QM/MM approaches have rapidly become one of the most popular computational tools for studying chemical reactivity in biomolecular systems. However, the high cost involved in performing high-level QM calculations has limited the applicability of these approaches when calculating free energies of chemical processes. In this review, we present some of the advances in using reference potentials and mean field approximations to accelerate high-level QM/MM calculations. We present illustrative applications of these approaches and discuss challenges and future perspectives for the field. The use of physically-based simplifications has shown to effectively reduce the cost of high-level QM/MM calculations. In particular, lower-level reference potentials enable one to reduce the cost of expensive free energy calculations, thus expanding the scope of problems that can be addressed. As was already demonstrated 40 years ago, the usage of simplified models still allows one to obtain cutting edge results with substantially reduced computational cost. This article is part of a Special Issue entitled Recent developments of molecular dynamics. Copyright © 2014. Published by Elsevier B.V.

Doxycycline Compliance at Bagram Air Field

DTIC Science & Technology

2014-05-01

doxycycline absorption. In 2008, the Institute of Medicine issued a report entitled ·’Use of Dietary Supplements by Military Personnel" that reported 34...absorption by tetracycline. Br J Clin Pharmacal. 1975 February; 2(1): 94- 96. 19. 0. M. e. Greenwood MRC, "Use of Dietary Supplements by Military...Personnel.Institute of Medicine (US) Committee on Dietary Supplement Use by Military Personnel," National Academies Press, Washington (DC), 2008. 20

An Alternative Way of Responding to Powerful Ideas: Notes to Accompany the Poem Entitled "Five Principles of Quality in Narratives of Action Research"

ERIC Educational Resources Information Center

Saunders, Lesley

2007-01-01

This paper is written in a personal capacity and mainly takes the form of a poem--in five sections--composed as a response to some of the ideas in the article by Hannu Heikkinen and colleagues in this same issue of "Educational Action Research": "Action research as narrative: five principles for validation". The poem takes its…

Traumatic Brain Injury Recovery Care: Demand Forecasting Staffing, and Treatment Planning

DTIC Science & Technology

2013-03-21

order to provide service to more wounded, ill and injured ( WII ), while continuing to provide a high quality and valuable service. There are...These wounded, ill, or injured ( WII ) troops will be diagnosed and receive treatment at specialty clinics. Once they have completed the necessary...most issues arising with military pay, benefits, entitlements, transition to civilian at medical board , etc. The RCP handles the medical treatment

Block-Time Classes and the Core Program in the Junior High School. Bulletin, 1958, No. 6

ERIC Educational Resources Information Center

Wright, Grace S.

1958-01-01

By this study, as by several it has issued in the past few years the Office of Education recognizes the interest of many educators in the core program as a means of achieving some of the objectives of general education at the secondary level. Its first publication, Bulletin 1950, No. 5 entitled "Core Curriculum in Public High Schools," a study of…

Neuro-Holistic Learning©: An Integrated Kinesthetic Approach to Cognitive Learning© Using Collaborative Interactive Thought Exchange© in a Blended Environment to Enhance the Learning of Young African American Males

ERIC Educational Resources Information Center

Osler, James Edward, II; Wright, Mark Anthony

2016-01-01

This paper is part two of the article entitled, "Dynamic Neuroscientific Systemology: Using Tri-Squared Meta-Analysis and Innovative Instructional Design to Develop a Novel Distance Education Model for the Systemic Creation of Engaging Online Learning Environments" published in the July-September 2015 issue of i-manager's "Journal…

Federal policies to promote the widespread utilization of photovoltaic systems. Supplement: Review and critique

NASA Technical Reports Server (NTRS)

Smith, J. L.

1980-01-01

Review comments of the Congressional report entitled 'Federal Policies to Promote the Widespread Utilization of Photovoltaic Systems' are presented. Responses to the review comments by the Jet Propulsion Laboratory, preparer of the Congressional report, are also presented. The Congressional report discussed various issues related to promoting the deployment of photovoltaic systems through the Federal Photovoltaic Program. Various program strategies and funding levels were examined.

Mexico-U.S. Relations: Issues for Congress

DTIC Science & Technology

2009-04-14

highways beyond the commercial zone. Sugar and High Fructose Corn Syrup The United States and Mexico resolved a long standing trade dispute involving...sugar and high fructose corn syrup in 2006. Mexico argued that the sugar side letter negotiated under NAFTA entitled it to ship net sugar surplus to...complained that imports of high fructose corn syrup (HFCS) sweeteners from the United States constituted dumping, and it imposed anti-dumping duties

A Critique of Julie L. Ozanne, Natalie Ross Adkins, and Jennifer A. Sandlin's: "Shopping {For} Power: How Adult Literacy Learners Negotiate"

ERIC Educational Resources Information Center

Coutinho, Colin

2008-01-01

This paper will review the article entitled, "Shopping {For} Power: How Adult Literacy Learners Negotiate" [EJ756994] by authors Julie L. Ozanne, Natalie Ross Adkins, and Jennifer A. Sandlin. The authors argue that functional literacy in the United States is an important issue and needs to play a larger role in adult literacy programs.…

78 FR 79480 - Notice of Receipt of Complaint; Solicitation of Comments Relating to the Public Interest

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-30

...Notice is hereby given that the U.S. International Trade Commission has received a complaint entitled Certain Vision-Based Driver Assistance System Cameras and Components Thereof, DN 2993; the Commission is soliciting comments on any public interest issues raised by the complaint or complainant's filing under section 210.8(b) of the Commission's Rules of Practice and Procedure (19 CFR 210.8(b)).

National Health Expenditures, 1982

PubMed Central

Gibson, Robert M.; Waldo, Daniel R.; Levit, Katharine R.

1983-01-01

Rapid growth in the share of the nation's gross national product devoted to health expenditure has heightened concern over the survival of government entitlement programs and has led to debate of the desirability of current methods of financing health care. In this article, the authors present the data at the heart of the issue, quantifying spending for various types of health care in 1982 and discussing the sources of funds for that spending. PMID:10310273

First Annual High-Speed Research Workshop, part 1

NASA Technical Reports Server (NTRS)

Whitehead, Allen H., Jr. (Compiler)

1992-01-01

The workshop was presented to provide a national forum for the government, industry, and university participants in the program to present and discuss important technology issues related to the development of a commercially viable, environmentally compatible U.S. High Speed Civil Transport. The workshop sessions were organized around the major task elements in NASA's Phase 1 High Speed Research Program which basically addressed the environmental issues of atmospheric emissions, community noise, and sonic boom. This volume is divided into three sessions entitled: Plenary Session (which gives overviews from NASA, Boeing, Douglas, GE, and Pratt & Whitney on the HSCT program); Airframe Systems Studies; and Atmospheric Effects.

Preface: Special Topic: From Quantum Mechanics to Force Fields.

PubMed

Piquemal, Jean-Philip; Jordan, Kenneth D

2017-10-28

This Special Topic issue entitled "From Quantum Mechanics to Force Fields" is dedicated to the ongoing efforts of the theoretical chemistry community to develop a new generation of accurate force fields based on data from high-level electronic structure calculations and to develop faster electronic structure methods for testing and designing force fields as well as for carrying out simulations. This issue includes a collection of 35 original research articles that illustrate recent theoretical advances in the field. It provides a timely snapshot of recent developments in the generation of approaches to enable more accurate molecular simulations of processes important in chemistry, physics, biophysics, and materials science.

History of the Tinnitus Research Consortium.

PubMed

Snow, James B

2016-04-01

This article describes the creation and accomplishments of the Tinnitus Research Consortium (TRC), founded and supported through philanthropy and intended to enrich the field of tinnitus research. Bringing together a group of distinguished auditory researchers, most of whom were not involved in tinnitus research, over the fifteen years of its life it developed novel research approaches and recruited a number of new investigators into the field. The purpose of this special issue is to highlight some of the significant accomplishments of the investigators supported by the TRC. This article is part of a Special Issue entitled "Tinnitus". Copyright © 2015 Elsevier B.V. All rights reserved.

Preface: Special Topic: From Quantum Mechanics to Force Fields

NASA Astrophysics Data System (ADS)

Piquemal, Jean-Philip; Jordan, Kenneth D.

2017-10-01

This Special Topic issue entitled "From Quantum Mechanics to Force Fields" is dedicated to the ongoing efforts of the theoretical chemistry community to develop a new generation of accurate force fields based on data from high-level electronic structure calculations and to develop faster electronic structure methods for testing and designing force fields as well as for carrying out simulations. This issue includes a collection of 35 original research articles that illustrate recent theoretical advances in the field. It provides a timely snapshot of recent developments in the generation of approaches to enable more accurate molecular simulations of processes important in chemistry, physics, biophysics, and materials science.

The Illinois Century Network: New Dimensions for Education in Illinois. A Vision for Communications and Computing Networking To Retain and Expand Illinois' Position as a World Leader by the Turn of the Century. Report and First-Phase Recommendations of the Higher Education Technology Task Force to the Illinois Board of Higher Education and the Illinois Community College Board.

ERIC Educational Resources Information Center

Illinois State Board of Higher Education, Springfield.

This proposal calls on the state of Illinois to initiate a statewide computing and telecommunications network that would give its residents access to higher education, advanced training, and electronic information resources. The proposed network, entitled Illinois Century Network, would link all higher education institutions in the state to…

New techniques for positron emission tomography in the study of human neurological disorders

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kuhl, D.E.

1993-01-01

This progress report describes accomplishments of four programs. The four programs are entitled (1) Faster,simpler processing of positron-computing precursors: New physicochemical approaches, (2) Novel solid phase reagents and methods to improve radiosynthesis and isotope production, (3) Quantitative evaluation of the extraction of information from PET images, and (4) Optimization of tracer kinetic methods for radioligand studies in PET.

Learning the Rules of the Game: The Nature of Game and Classroom Supports When Using a Concept-Integrated Digital Physics Game in the Middle School Science Classroom

ERIC Educational Resources Information Center

Stewart, Phillip Michael, Jr.

2013-01-01

Games in science education is emerging as a popular topic of scholarly inquiry. The National Research Council recently published a report detailing a research agenda for games and science education entitled "Learning Science Through Computer Games and Simulations" (2011). The report recommends moving beyond typical proof-of-concept…

20 CFR 217.8 - When one application satisfies the filing requirement for other benefits.

Code of Federal Regulations, 2012 CFR

2012-04-01

... employee died. (g) A child's annuity or child's full-time student annuity if the child of the employee was.... (d) A widow(er)'s annuity if the widow(er) was entitled to a spouse annuity in the month before the month the employee died. (e) A widow(er)'s annuity if the widow(er) was included in the computation of...

20 CFR 217.8 - When one application satisfies the filing requirement for other benefits.

Code of Federal Regulations, 2011 CFR

2011-04-01

... employee died. (g) A child's annuity or child's full-time student annuity if the child of the employee was.... (d) A widow(er)'s annuity if the widow(er) was entitled to a spouse annuity in the month before the month the employee died. (e) A widow(er)'s annuity if the widow(er) was included in the computation of...

20 CFR 217.8 - When one application satisfies the filing requirement for other benefits.

Code of Federal Regulations, 2010 CFR

2010-04-01

... employee died. (g) A child's annuity or child's full-time student annuity if the child of the employee was.... (d) A widow(er)'s annuity if the widow(er) was entitled to a spouse annuity in the month before the month the employee died. (e) A widow(er)'s annuity if the widow(er) was included in the computation of...

20 CFR 217.8 - When one application satisfies the filing requirement for other benefits.

Code of Federal Regulations, 2014 CFR

2014-04-01

... employee died. (g) A child's annuity or child's full-time student annuity if the child of the employee was.... (d) A widow(er)'s annuity if the widow(er) was entitled to a spouse annuity in the month before the month the employee died. (e) A widow(er)'s annuity if the widow(er) was included in the computation of...

20 CFR 217.8 - When one application satisfies the filing requirement for other benefits.

Code of Federal Regulations, 2013 CFR

2013-04-01

... employee died. (g) A child's annuity or child's full-time student annuity if the child of the employee was.... (d) A widow(er)'s annuity if the widow(er) was entitled to a spouse annuity in the month before the month the employee died. (e) A widow(er)'s annuity if the widow(er) was included in the computation of...

Putting third first: critical legal issues and HIV/AIDS.

PubMed

2000-01-01

On 7 July 2000, before the XIII International AIDS Conference, the Canadian HIV/AIDS Legal Network and the AIDS Law Project, South Africa held a one-day satellite meeting on legal, ethical, and human rights issues in Durban, South Africa. Entitled Putting Third First--Critical Legal Issues and HIV/AIDS, the satellite focused on legal strategies to advance the human rights of those most vulnerable to HIV/AIDS and to discrimination: people in the developing world, and people who, although they live in the industrialized world, suffer from poverty and marginalization and are at high risk of contracting HIV. The satellite grew out of the ongoing partnership between the Canadian HIV/AIDS Legal Network and the AIDS Law Project, South Africa, and was co-hosted by UNAIDS.

Special Issue: "Molecules against Alzheimer".

PubMed

Decker, Michael; Muñoz-Torrero, Diego

2016-12-16

This Special Issue, entitled "Molecules against Alzheimer", gathers a number of original articles, short communications, and review articles on recent research efforts toward the development of novel drug candidates, diagnostic agents and therapeutic approaches for Alzheimer's disease (AD), the most prevalent neurodegenerative disorder and a leading cause of death worldwide. This Special Issue contains many interesting examples describing the design, synthesis, and pharmacological profiling of novel compounds that hit one or several key biological targets, such as cholinesterases, β-amyloid formation or aggregation, monoamine oxidase B, oxidative stress, biometal dyshomeostasis, mitochondrial dysfunction, serotonin and/or melatonin systems, the Wnt/β-catenin pathway, sigma receptors, nicotinamide phosphoribosyltransferase, or nuclear erythroid 2-related factor. The development of novel AD diagnostic agents based on tau protein imaging and the use of lithium or intranasal insulin for the prevention or the symptomatic treatment of AD is also covered in some articles of the Special Issue.

Shaping the Future of Mathematics Education. Proceedings of the Annual Conference of the Mathematics Education Research Group of Australasia (33rd, Freemantle, Western Australia, Australia, July 3-7, 2010)

ERIC Educational Resources Information Center

Sparrow, Len, Ed.; Kissane, Barry, Ed.; Hurst, Chris, Ed.

2010-01-01

These collected papers are a record of the proceedings of the 33rd Annual Conference of the Mathematics Education Research Group of Australasia entitled, "Shaping the Future of Mathematics Education." The conference is held in Fremantle, as was the previous conference a decade earlier. Keynote speakers are discussing issues that are emerging more…

78 FR 35940 - Content of Premarket Submissions for Management of Cybersecurity in Medical Devices; Draft...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-14

...The Food and Drug Administration (FDA) is announcing the availability of the draft guidance entitled ``Content of Premarket Submissions for Management of Cybersecurity in Medical Devices.'' This guidance identifies cybersecurity issues that manufacturers should consider in preparing premarket submissions for medical devices in order to maintain information confidentiality, integrity, and availability. This draft guidance is not final nor is it in effect at this time.

Major Management Challenges and Program Risks. Department of State

DTIC Science & Technology

2001-01-01

Major Management Challenges and Program Risks Department of StateGAO-01-252 Form SF298 Citation Data Report Date ("DD MON YYYY") 00JAN2001 Report...Type N/A Dates Covered (from... to) ("DD MON YYYY") Title and Subtitle Major Management Challenges and Program Risks Department of State Contract or...special series, first issued in January 1999, entitled the Performance and Accountability Series: Major Management Challenges and Program Risks . In

Major Management Challenges and Program Risks. Department of the Interior

DTIC Science & Technology

2001-01-01

Major Management Challenges and Program Risks Department of the InteriorGAO-01-249 Report Date ("DD MON YYYY") 00JAN2001 Report Type N/A Dates...Covered (from... to) ("DD MON YYYY") Title and Subtitle Major Management Challenges and Program Risks Department of the Interior Contract or Grant...first issued in January 1999, entitled the Performance and Accountability Series: Major Management Challenges and Program Risks . In that series, GAO

Workshop on Production and Uses of Simulated Lunar Materials

NASA Technical Reports Server (NTRS)

1991-01-01

A workshop entitled, Production and Uses of Simulated Lunar Materials, was convened to define the need for simulated lunar materials and examine related issues in support of extended space exploration and development. Lunar samples are a national treasure and cannot be sacrificed in sufficient quantity to test lunar resource utilization process adequately. Hence, the workshop focused on a detailed examination of the variety of potential simulants and the methods for their production.

De-radicalization: You Can Check Out Anytime You Like, But What Will Make You Leave

DTIC Science & Technology

2010-12-01

comes to describing individual motivations, Abraham Maslow captures the essence of the issue in a 1943 paper entitled A Theory of Human Motivation...behavior until they are fulfilled to a basic degree. 3 Abraham Maslow , "A Theory of Human...Human: A Biography of Abraham Maslow , succinctly described the premise of self-actualization, “In the core of our being we each carry the seed of our

Mexico-U.S. Relations: Issues for Congress

DTIC Science & Technology

2009-05-13

zone. Sugar and High Fructose Corn Syrup The United States and Mexico resolved a long standing trade dispute involving sugar and high fructose ... high fructose corn syrup (HFCS) sweeteners from the United States constituted dumping, and it imposed anti-dumping duties for some time, until NAFTA... corn syrup in 2006. Mexico argued that the sugar side letter negotiated under NAFTA entitled it to ship net sugar surplus to the United States duty free

Stressing on the nucleolus in cardiovascular disease.

PubMed

Hariharan, Nirmala; Sussman, Mark A

2014-06-01

The nucleolus is a multifunctional organelle with multiple roles involving cell proliferation, growth, survival, ribosome biogenesis and stress response signaling. Alteration of nucleolar morphology and architecture signifies an early response to increased cellular stress. This review briefly summarizes nucleolar response to cardiac stress signals and details the role played by nucleolar proteins in cardiovascular pathophysiology. This article is part of a Special Issue entitled: Role of the Nucleolus in Human Disease. © 2013.

The Roles of Science and Technology in General and Continuing Education. Proceedings of the Conference of the Association of American Colleges (Washington, District of Columbia, December 16-18, 1979).

ERIC Educational Resources Information Center

Association of American Colleges, Washington, DC.

This conference focused on issues and topics related to the roles of science and technology in general and continuing education. The keynote address is entitled "Technology Transfer to the Third World: The Critical U.S. Challenge for the Eighties" (William Eilers). The section on perspectives on the public understanding of science includes the…

The Development of Children's Understanding of Distant Places and Environmental Issues: Report of a UK Longitudinal Study of the Development of Ideas between the Ages of 4 and 10 Years

ERIC Educational Resources Information Center

Palmer, Joy A.; Suggate, Jennifer

2004-01-01

The research reported here forms part of a major international study entitled "Emergent Environmentalism". The overall purpose of the Emergent Environmentalism research is to investigate the acquisition and development of environmental knowledge, awareness and concern in both adults and young children. This report is of the results of one aspect…

Maritime Territorial and Exclusive Economic Zone (EEZ) Disputes Involving China: Issues for Congress

DTIC Science & Technology

2016-04-01

lines from which the breadth of maritime entitlements are measured ) that are inconsistent with international law, including Vietnam and China, and...committed to pursue an arrangement whose intended purpose is equivalent to the Rules of Behavior Confidence Building Measure annex on surface-to-surface...International Studies), February 4, 2015; Mira Rapp-Hooper, “What’s in a Confidence Building Measure ?” Lawfare, February 8, 2015; Peter Dutton and

A course designed for undergraduate biochemistry students to learn about cultural diversity issues.

PubMed

Benore-Parsons, Marilee

2006-09-01

Biology, biochemistry, and other science students are well trained in science and familiar with how to conduct and evaluate scientific experiments. They are less aware of cultural issues or how these will impact their careers in research, education, or as professional health care workers. A course was developed for advanced undergraduate science majors to learn about diversity issues in a context that would be relevant to them, entitled "Diversity Issues in Health Care: Treatment and Research." Learning objectives included: developing awareness of current topics concerning diversity issues in health care; learning how research is carried out in health care, including pharmaceutical research, clinical trials, and social research; and learning about health care practices. Lectures and projects included readings on laboratory and clinical research, as well as literature on legal, race, gender, language, age, and income issues in health care research and clinical practice. Exams, papers, and a service learning project were used to determine the final course grade. Assessment indicated student understanding of diversity issues was improved, and the material was relevant. Copyright © 2006 International Union of Biochemistry and Molecular Biology, Inc.

38 CFR 21.9570 - Transfer of entitlement.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2014-07-01 2014-07-01 false Transfer of entitlement... (CONTINUED) VOCATIONAL REHABILITATION AND EDUCATION Post-9/11 GI Bill Transfer of Entitlement to Basic Educational Assistance to Dependents § 21.9570 Transfer of entitlement. An individual entitled to educational...

38 CFR 21.9570 - Transfer of entitlement.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2013-07-01 2013-07-01 false Transfer of entitlement... (CONTINUED) VOCATIONAL REHABILITATION AND EDUCATION Post-9/11 GI Bill Transfer of Entitlement to Basic Educational Assistance to Dependents § 21.9570 Transfer of entitlement. An individual entitled to educational...

38 CFR 21.9570 - Transfer of entitlement.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2011-07-01 2011-07-01 false Transfer of entitlement... (CONTINUED) VOCATIONAL REHABILITATION AND EDUCATION Post-9/11 GI Bill Transfer of Entitlement to Basic Educational Assistance to Dependents § 21.9570 Transfer of entitlement. An individual entitled to educational...

38 CFR 21.9570 - Transfer of entitlement.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2012-07-01 2012-07-01 false Transfer of entitlement... (CONTINUED) VOCATIONAL REHABILITATION AND EDUCATION Post-9/11 GI Bill Transfer of Entitlement to Basic Educational Assistance to Dependents § 21.9570 Transfer of entitlement. An individual entitled to educational...

A Typology of Students Based on Academic Entitlement

ERIC Educational Resources Information Center

Luckett, Michael; Trocchia, Philip J.; Noel, Noel Mark; Marlin, Dan

2017-01-01

Two hundred ninety-three university business students were surveyed using an academic entitlement (AE) scale updated to include new technologies. Using factor analysis, three components of AE were identified: grade entitlement, behavioral entitlement, and service entitlement. A k-means clustering procedure was then applied to identify four groups…

New techniques for positron emission tomography in the study of human neurological disorders. Progress report, June 1990--June 1993

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kuhl, D.E.

1993-06-01

This progress report describes accomplishments of four programs. The four programs are entitled (1) Faster,simpler processing of positron-computing precursors: New physicochemical approaches, (2) Novel solid phase reagents and methods to improve radiosynthesis and isotope production, (3) Quantitative evaluation of the extraction of information from PET images, and (4) Optimization of tracer kinetic methods for radioligand studies in PET.

A Contract Management Guide for Air Force Environmental Restoration

DTIC Science & Technology

1991-09-01

literature in their area of interest in an attempt to locate a market niche. These topical studies often take the form of guides to specific areas of the...computer remote bulletin board system entitled the Hazardous Materials Information Exchange (HMIX). HMIX has information on training for response to... market for two reasons: the size of the appropriations under the Superfund Amendment and Reauthorization Act, and the huge number of contaminated

User Interface on the World Wide Web: How to Implement a Multi-Level Program Online

NASA Technical Reports Server (NTRS)

Cranford, Jonathan W.

1995-01-01

The objective of this Langley Aerospace Research Summer Scholars (LARSS) research project was to write a user interface that utilizes current World Wide Web (WWW) technologies for an existing computer program written in C, entitled LaRCRisk. The project entailed researching data presentation and script execution on the WWW and than writing input/output procedures for the database management portion of LaRCRisk.

20 CFR 410.215 - Duration of entitlement; parent, brother, or sister.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Duration of entitlement; parent, brother, or...; Duration of Entitlement; Filing of Claims and Evidence § 410.215 Duration of entitlement; parent, brother, or sister. (a) parent, brother, or sister is entitled to benefits beginning with the month all the...

20 CFR 410.214 - Conditions of entitlement; parent, brother, or sister.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Conditions of entitlement; parent, brother...; Duration of Entitlement; Filing of Claims and Evidence § 410.214 Conditions of entitlement; parent, brother, or sister. An individual is entitled to benefits if: (a) Such individual: (1) Is the parent, brother...

An introduction to the special issue on Geoscience Papers of the Future

NASA Astrophysics Data System (ADS)

David, Cédric H.; Gil, Yolanda; Duffy, Christopher J.; Peckham, Scott D.; Venayagamoorthy, S. Karan

2016-10-01

Advocates of enhanced quality for published scientific results are increasingly voicing the need for further transparency of data and software for scientific reproducibility. However, such advanced digital scholarship can appear perplexing to geoscientists that are seduced by the concept of open science yet wonder about the exact mechanics and implications of the associated efforts. This special issue of Earth and Space Science entitled "Geoscience Papers of the Future" includes a review of existing best practices for digital scholarship and bundles a set of example articles that share their digital research products and reflect on the process of opening their scientific approach in a common quest for reproducible science.

Reforms in pedagogy and the Confucian tradition: looking below the surface

NASA Astrophysics Data System (ADS)

Ho, Felix M.

2018-03-01

This Forum article addresses some of the issues raised in the article by Ying-Syuan Huang and Anila Asghar's paper entitled: Science education reform in Confucian learning cultures: teachers' perspectives on policy and practice in Taiwan. An attempt is made to highlight the need for a more nuanced approach in considering the Confucian education tradition and its compatibility with education reforms. In particular, the article discusses issues concerning the historical development of the Confucian education tradition, challenges in reform implementation that are in reality tradition-independent, as well as opportunities and points of convergence that the Confucian education tradition presents that can in fact be favorable to implementation of reform-based pedagogies.

Human Rights and Dignity Behind Bars.

PubMed

Maschi, Tina; Richter, Marina

2017-01-01

Death and dying in prisons constitute a topic of growing importance across the globe. Based on the contributions made in this special issue, we reflect on current debates and outline recommendations for dialogue and practice. Scientific dialogue across the Atlantic, and across the globe, provides insights into different national carceral systems and their ways of dealing with end of life behind bars. At the same time, the comparison also helps to identify basic needs and practices that can work in various settings. We identify several issues where further efforts need to be taken to deepen the dialogue. A common ground for all advancement of legislation and practice constitute the minimal level of rights to which every human being is entitled.

Recent advances in QM/MM free energy calculations using reference potentials☆

PubMed Central

Duarte, Fernanda; Amrein, Beat A.; Blaha-Nelson, David; Kamerlin, Shina C.L.

2015-01-01

Background Recent years have seen enormous progress in the development of methods for modeling (bio)molecular systems. This has allowed for the simulation of ever larger and more complex systems. However, as such complexity increases, the requirements needed for these models to be accurate and physically meaningful become more and more difficult to fulfill. The use of simplified models to describe complex biological systems has long been shown to be an effective way to overcome some of the limitations associated with this computational cost in a rational way. Scope of review Hybrid QM/MM approaches have rapidly become one of the most popular computational tools for studying chemical reactivity in biomolecular systems. However, the high cost involved in performing high-level QM calculations has limited the applicability of these approaches when calculating free energies of chemical processes. In this review, we present some of the advances in using reference potentials and mean field approximations to accelerate high-level QM/MM calculations. We present illustrative applications of these approaches and discuss challenges and future perspectives for the field. Major conclusions The use of physically-based simplifications has shown to effectively reduce the cost of high-level QM/MM calculations. In particular, lower-level reference potentials enable one to reduce the cost of expensive free energy calculations, thus expanding the scope of problems that can be addressed. General significance As was already demonstrated 40 years ago, the usage of simplified models still allows one to obtain cutting edge results with substantially reduced computational cost. This article is part of a Special Issue entitled Recent developments of molecular dynamics. PMID:25038480

Code of Ethical Conduct for Computer-Using Educators: An ICCE Policy Statement.

ERIC Educational Resources Information Center

Computing Teacher, 1987

1987-01-01

Prepared by the International Council for Computers in Education's Ethics and Equity Committee, this code of ethics for educators using computers covers nine main areas: curriculum issues, issues relating to computer access, privacy/confidentiality issues, teacher-related issues, student issues, the community, school organizational issues,…

In silico methods in the discovery of endocrine disrupting chemicals.

PubMed

Vuorinen, Anna; Odermatt, Alex; Schuster, Daniela

2013-09-01

The prevalence of sex hormone-dependent cancers, reproductive problems, obesity, and cardiovascular complications has risen especially in the Western world. It has been suggested, that the exposure to various endocrine disrupting chemicals (EDCs) contributes to the development and progression of these diseases. EDCs can interfere with various proteins: nuclear steroid hormone receptors, such as estrogen-, androgen-, glucocorticoid- and mineralocorticoid receptors (ER, AR, GR, MR), and enzymes that are involved in steroid hormone synthesis and metabolism, for example hydroxysteroid dehydrogenases (HSDs). Numerous chemicals are known as endocrine disruptors. However, the mechanism of action for most of these EDCs is still unknown. It is exhaustive and time consuming to test in vitro all chemicals - potential EDCs - used in industry, agriculture or as food preservatives against their effects on the endocrine system. Computational methods, such as virtual screening, quantitative structure activity relationships and docking, are already well recognized and used in drug development. The same methods could also aid the research on EDCs. So far, the computational methods in the search of EDCs have been retrospective. There are, however, some prospective studies reporting the use of in silico methods: five studies reporting the identification of previously unknown 17β-HSD3 inhibitors, MR agonists, and ER antagonists/agonists. This review provides an overview of case studies and in silico methods that are used in the search of EDCs. This article is part of a Special Issue entitled 'CSR 2013'. Copyright © 2013 Elsevier Ltd. All rights reserved.

Reprint of "In silico methods in the discovery of endocrine disrupting chemicals".

PubMed

Vuorinen, Anna; Odermatt, Alex; Schuster, Daniela

2015-09-01

The prevalence of sex hormone-dependent cancers, reproductive problems, obesity, and cardiovascular complications has risen especially in the Western world. It has been suggested, that the exposure to various endocrine disrupting chemicals (EDCs) contributes to the development and progression of these diseases. EDCs can interfere with various proteins: nuclear steroid hormone receptors, such as estrogen-, androgen-, glucocorticoid- and mineralocorticoid receptors (ER, AR, GR, MR), and enzymes that are involved in steroid hormone synthesis and metabolism, for example hydroxysteroid dehydrogenases (HSDs). Numerous chemicals are known as endocrine disruptors. However, the mechanism of action for most of these EDCs is still unknown. It is exhaustive and time consuming to test in vitro all chemicals - potential EDCs - used in industry, agriculture or as food preservatives against their effects on the endocrine system. Computational methods, such as virtual screening, quantitative structure activity relationships and docking, are already well recognized and used in drug development. The same methods could also aid the research on EDCs. So far, the computational methods in the search of EDCs have been retrospective. There are, however, some prospective studies reporting the use of in silico methods: five studies reporting the identification of previously unknown 17β-HSD3 inhibitors, MR agonists, and ER antagonists/agonists. This review provides an overview of case studies and in silico methods that are used in the search of EDCs. This article is part of a Special Issue entitled 'CSR 2013'. Copyright © 2015 Elsevier Ltd. All rights reserved.

42 CFR 406.12 - Individual under age 65 who is entitled to social security or railroad retirement disability...

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 2 2011-10-01 2011-10-01 false Individual under age 65 who is entitled to social... is entitled to social security or railroad retirement disability benefits. (a) Basic requirements. An...) Entitled or deemed entitled to social security disability benefits as an insured individual, child, widow...

"I Bought My Degree, Now I Want My Job!" Is Academic Entitlement Related to Prospective Workplace Entitlement?

ERIC Educational Resources Information Center

Peirone, Amy; Maticka-Tyndale, Eleanor

2017-01-01

Academic entitlement, a term that defines students' expectations of academic success independent of performance, has been linked with a number of maladaptive behaviors. This study examined the potential relationship between academic entitlement and prospective workplace entitlement in a sample of Canadian students (N=1024) using an online survey.…

42 CFR 406.12 - Individual under age 65 who is entitled to social security or railroad retirement disability...

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 2 2013-10-01 2013-10-01 false Individual under age 65 who is entitled to social... is entitled to social security or railroad retirement disability benefits. (a) Basic requirements. An...) Entitled or deemed entitled to social security disability benefits as an insured individual, child, widow...

42 CFR 406.12 - Individual under age 65 who is entitled to social security or railroad retirement disability...

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 2 2012-10-01 2012-10-01 false Individual under age 65 who is entitled to social... is entitled to social security or railroad retirement disability benefits. (a) Basic requirements. An...) Entitled or deemed entitled to social security disability benefits as an insured individual, child, widow...

42 CFR 406.12 - Individual under age 65 who is entitled to social security or railroad retirement disability...

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 2 2010-10-01 2010-10-01 false Individual under age 65 who is entitled to social... is entitled to social security or railroad retirement disability benefits. (a) Basic requirements. An...) Entitled or deemed entitled to social security disability benefits as an insured individual, child, widow...

Famine as agricultural catastrophe: the crisis of 1622-4 in east Lancashire.

PubMed

Hoyle, R W

2010-01-01

This article argues that historians have paid insufficient attention to the agrarian roots of early modern English famines. While not dismissing the insights arising from entitlements theory, the article takes issue with recent writings that have explained the famine of 1622–3 in north-west England as an entitlements crisis. It offers new empirical evidence from an estate in east Lancashire to demonstrate the scale of the crisis in the early 1620s, using estate accounts to produce new price data and estimates of productivity. On the basis of oat tithe data, the scale of the shortfall in foodstuffs in the harvest of 1621 is demonstrated as being probably in the region of a third; that of the following year has to be inferred from price data. The evidence shows that the crisis was not limited to the arable economy, but was followed by an extensive restocking of the pastoral economy. The article therefore makes a contribution to the growing interest in weather as an exogenous factor.

Proceedings of second geopressured geothermal energy conference, Austin, Texas, February 23--25, 1976. Volume V. Legal, institutional, and environmental

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vanston, J.H.; Elmer, D.B.; Gustavson, T.C.

Three separate abstracts were prepared for Volume V of the Proceedings of the Conference. Sections are entitled: Legal Issues in the Development of Geopressured--Geothermal Resources of Texas and Louisiana Gulf Coast; The Development of Geothermal Energy in the Gulf Coast; Socio-economic, Demographic, and Political Considerations; and Geothermal Resources of the Texas Gulf Coast--Environmental Concerns arising from the Production and Disposal of Geothermal waters. (MCW)

The K-turn motif in riboswitches and other RNA species☆

PubMed Central

Lilley, David M.J.

2014-01-01

The kink turn is a widespread structure motif that introduces a tight bend into the axis of duplex RNA. This generally functions to mediate tertiary interactions, and to serve as a specific protein binding site. K-turns or closely related structures are found in at least seven different riboswitch structures, where they function as key architectural elements that help generate the ligand binding pocket. This article is part of a Special Issue entitled: Riboswitches. PMID:24798078

Comments on Professor Lortie's Paper Entitled "The Cracked Cake of Educational Custom and Emerging Issues in Evaluation." Center for the Study of Evaluation of Instructional Programs Occasional Report No. 20.

ERIC Educational Resources Information Center

Gordon, C. Wayne

This paper suggests that the variety of decision making proposed by Professor Lortie will not afford the luxury of evaluative systems of the kind he describes. Professor Gordon feels that, had Professor Lortie pursued a line of functional analysis of many outcomes, he would have arrived at an entirely new analysis of the justification for…

Chemical Reactions in Turbulent Mixing Flows

DTIC Science & Technology

1991-09-14

explored Reynolds number effects on turbulent flame length and the influence of buoyancy on turbulent jet flames; 2. completion of a thesis entitled...the dependence of flame length on Reynolds number was begun, and the issue of buoyancy was investigated. L._Lw~ Pt-lO%Rh 2 ൡ g rn wire Flame L ZoneY...105. The flame length at a given Reynolds number was determined from the time-averaged, line- integrated temperature measurements performed by the cold

U.S. Army War College Guide to National Security Issues. Volume 2. National Security Policy and Strategy

DTIC Science & Technology

2012-06-01

1998 National War College paper entitled “U.S. National Se- curity Structure: A New Model for the 21st Century” defines the national security community ...fueled by revolu- tions in communications and information management, the emergence of a truly global market and world economy, the primacy of economic...collection of information is estimated to average 1 hour per response, including the time for reviewing instructions , searching existing data sources

U.S.-Mexico Economic Relations: Trends, Issues, and Implications

DTIC Science & Technology

2009-04-03

and high fructose corn syrup . Mexico argued that the sugar side letter negotiated under NAFTA entitled it to ship net sugar surplus to the United...that imports of high fructose corn syrup (HFCS) sweeteners from the United States constituted dumping, and it imposed anti-dumping duties for some time...industries to restrict HFCS imports from the United States. In late 2001, the Mexican Congress imposed a 20% tax on soft drinks made with corn syrup

Joint Force Quarterly. Issue 63, 4th Quarter 2011

DTIC Science & Technology

2011-10-01

wondrous trinity” for use in the current threat environment, Mr. Owens could refer to my piece entitled “The Age of Irregular Warfare: So What...listen, but its future enemy did. When it comes to good ideas, neither rank nor age confers a monopoly. JFQ is intended to stay at the vanguard, to...will need to evolve with an emphasis on rejuvenating and sustaining the country’s economic vitality while relying increasingly on credible forms of

Science textbooks for lower secondary schools in Brunei: issues of gender equity

NASA Astrophysics Data System (ADS)

Elgar, Ann G.

2004-07-01

This paper is concerned with issues affecting equity in science education for girls and boys. In the paper the results of an investigation into the recently published (1998-2000) series of textbooks entitled Lower Secondary Science for Brunei Darussalam are presented. In the first part of the paper, background issues of continuing gender inequality in science education and of the nature and scope of textbook analyses are outlined. Then the representation of males and females in both illustrations and text in the Bruneian textbooks is discussed. From this analysis a picture emerges of the extent to which science is portrayed as a pursuit of equal appropriateness for both boys and girls. The paper concludes with a consideration of the implications of the findings presented within the wider context of gender and education in Brunei.

International Conference on Harmonisation; guidance on the M4 Common Technical Document--Quality: Questions and Answers/Location Issues; availability. Notice.

PubMed

2004-06-09

The Food and Drug Administration (FDA) is announcing the availability of a guidance entitled "M4: The CTD--Quality: Questions and Answers/Location Issues." The guidance was prepared under the auspices of the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH). This guidance provides further clarification for preparing the quality components of an application file in the common technical document (CTD) format. The guidance addresses the relationship between linked sections for certain parameters (such as polymorphism and particle size), and it addresses location issues (by indicating the section in which to place requested information). The guidance is intended to ease the preparation of paper and electronic submissions, facilitate regulatory reviews, and simplify the exchange of regulatory information among regulatory authorities.

René Leriche and “Philosophy of Surgery” in the light of contemporary medical ethics

PubMed Central

Akça, Tamer; Aydın, Süha

2013-01-01

Prof. Dr. René Leriche was a famous French surgeon who lived between 1879 and 1955. After working as a vascular surgeon in Lyon, he was appointed professor at the University of Strasbourg in 1924 and later the Paris Collége de France in 1937. Leriche had proposed vascular patches as the ideal treatment for obliterated vascular segments and advocated the necessity of sympathectomy in arterial diseases in the 1920s. He defined “Leriche Syndrome” in 1923 which is known by his name and which develops as a result of incomplete obstruction of the aortic bifurcation. René Leriche wrote a monograph entitled “La Chirurgie de la Douleur-Pain Surgery” in 1940 and he also became a pioneer in the sympathectomy procedure for pain treatment. René Leriche focused on topics that must be remembered again today, including surgery advanced into science, the physiological basis of surgery, research methods, as well as issues such as business technology, humanity in surgery, surgical essence and surgeon’s qualifications in the book entitled “La Philosophie de la Chirurgie-Philosophy of Surgery” that he wrote in 1951. In this review, the issues that Prof. Dr. René Leriche addressed in middle of the 20th century were revised in the light of contemporary medical ethics. PMID:25931863

Open source libraries and frameworks for mass spectrometry based proteomics: A developer's perspective☆

PubMed Central

Perez-Riverol, Yasset; Wang, Rui; Hermjakob, Henning; Müller, Markus; Vesada, Vladimir; Vizcaíno, Juan Antonio

2014-01-01

Data processing, management and visualization are central and critical components of a state of the art high-throughput mass spectrometry (MS)-based proteomics experiment, and are often some of the most time-consuming steps, especially for labs without much bioinformatics support. The growing interest in the field of proteomics has triggered an increase in the development of new software libraries, including freely available and open-source software. From database search analysis to post-processing of the identification results, even though the objectives of these libraries and packages can vary significantly, they usually share a number of features. Common use cases include the handling of protein and peptide sequences, the parsing of results from various proteomics search engines output files, and the visualization of MS-related information (including mass spectra and chromatograms). In this review, we provide an overview of the existing software libraries, open-source frameworks and also, we give information on some of the freely available applications which make use of them. This article is part of a Special Issue entitled: Computational Proteomics in the Post-Identification Era. Guest Editors: Martin Eisenacher and Christian Stephan. PMID:23467006

Comparison of mechanistic transport cycle models of ABC exporters.

PubMed

Szöllősi, Dániel; Rose-Sperling, Dania; Hellmich, Ute A; Stockner, Thomas

2018-04-01

ABC (ATP binding cassette) transporters, ubiquitous in all kingdoms of life, carry out essential substrate transport reactions across cell membranes. Their transmembrane domains bind and translocate substrates and are connected to a pair of nucleotide binding domains, which bind and hydrolyze ATP to energize import or export of substrates. Over four decades of investigations into ABC transporters have revealed numerous details from atomic-level structural insights to their functional and physiological roles. Despite all these advances, a comprehensive understanding of the mechanistic principles of ABC transporter function remains elusive. The human multidrug resistance transporter ABCB1, also referred to as P-glycoprotein (P-gp), is one of the most intensively studied ABC exporters. Using ABCB1 as the reference point, we aim to compare the dominating mechanistic models of substrate transport and ATP hydrolysis for ABC exporters and to highlight the experimental and computational evidence in their support. In particular, we point out in silico studies that enhance and complement available biochemical data. "This article is part of a Special Issue entitled: Beyond the Structure-Function Horizon of Membrane Proteins edited by Ute Hellmich, Rupak Doshi and Benjamin McIlwain." Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.

Open source libraries and frameworks for mass spectrometry based proteomics: a developer's perspective.

PubMed

Perez-Riverol, Yasset; Wang, Rui; Hermjakob, Henning; Müller, Markus; Vesada, Vladimir; Vizcaíno, Juan Antonio

2014-01-01

Data processing, management and visualization are central and critical components of a state of the art high-throughput mass spectrometry (MS)-based proteomics experiment, and are often some of the most time-consuming steps, especially for labs without much bioinformatics support. The growing interest in the field of proteomics has triggered an increase in the development of new software libraries, including freely available and open-source software. From database search analysis to post-processing of the identification results, even though the objectives of these libraries and packages can vary significantly, they usually share a number of features. Common use cases include the handling of protein and peptide sequences, the parsing of results from various proteomics search engines output files, and the visualization of MS-related information (including mass spectra and chromatograms). In this review, we provide an overview of the existing software libraries, open-source frameworks and also, we give information on some of the freely available applications which make use of them. This article is part of a Special Issue entitled: Computational Proteomics in the Post-Identification Era. Guest Editors: Martin Eisenacher and Christian Stephan. Copyright © 2013 Elsevier B.V. All rights reserved.

Modelling the interactions between animal venom peptides and membrane proteins.

PubMed

Hung, Andrew; Kuyucak, Serdar; Schroeder, Christina I; Kaas, Quentin

2017-12-01

The active components of animal venoms are mostly peptide toxins, which typically target ion channels and receptors of both the central and peripheral nervous system, interfering with action potential conduction and/or synaptic transmission. The high degree of sequence conservation of their molecular targets makes a range of these toxins active at human receptors. The high selectivity and potency displayed by some of these toxins have prompted their use as pharmacological tools as well as drugs or drug leads. Molecular modelling has played an essential role in increasing our molecular-level understanding of the activity and specificity of animal toxins, as well as engineering them for biotechnological and pharmaceutical applications. This review focuses on the biological insights gained from computational and experimental studies of animal venom toxins interacting with membranes and ion channels. A host of recent X-ray crystallography and electron-microscopy structures of the toxin targets has contributed to a dramatic increase in the accuracy of the molecular models of toxin binding modes greatly advancing this exciting field of study. This article is part of the Special Issue entitled 'Venom-derived Peptides as Pharmacological Tools.' Copyright © 2017 Elsevier Ltd. All rights reserved.

Advances in understanding tumour evolution through single-cell sequencing.

PubMed

Kuipers, Jack; Jahn, Katharina; Beerenwinkel, Niko

2017-04-01

The mutational heterogeneity observed within tumours poses additional challenges to the development of effective cancer treatments. A thorough understanding of a tumour's subclonal composition and its mutational history is essential to open up the design of treatments tailored to individual patients. Comparative studies on a large number of tumours permit the identification of mutational patterns which may refine forecasts of cancer progression, response to treatment and metastatic potential. The composition of tumours is shaped by evolutionary processes. Recent advances in next-generation sequencing offer the possibility to analyse the evolutionary history and accompanying heterogeneity of tumours at an unprecedented resolution, by sequencing single cells. New computational challenges arise when moving from bulk to single-cell sequencing data, leading to the development of novel modelling frameworks. In this review, we present the state of the art methods for understanding the phylogeny encoded in bulk or single-cell sequencing data, and highlight future directions for developing more comprehensive and informative pictures of tumour evolution. This article is part of a Special Issue entitled: Evolutionary principles - heterogeneity in cancer?, edited by Dr. Robert A. Gatenby. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.

Molecules to maps: tools for visualization and interaction in support of computational biology.

PubMed

Kraemer, E T; Ferrin, T E

1998-01-01

The volume of data produced by genome projects, X-ray crystallography, NMR spectroscopy, and electron and confocal microscopy present the bioinformatics community with new challenges for analyzing, understanding, and exchanging this data. At the 1998 Pacific Symposium on Biocomputing, a track entitled 'Molecules to Maps: Tools for Visualization and Interaction in Computational Biology' provided tool developers and users with the opportunity to discuss advances in tools and techniques to assist scientists in evaluating, absorbing, navigating, and correlating this sea of information, through visualization and user interaction. In this paper we present these advances and discuss some of the challenges that remain to be solved.

Innovation and Integrity in Intervention Research: Conceptual Issues, Methodology, and Knowledge Translation.

PubMed

Malti, Tina; Beelmann, Andreas; Noam, Gil G; Sommer, Simon

2018-04-01

In this article, we introduce the special issue entitled Innovation and Integrity in Intervention Science. Its focus is on essential problems and prospects for intervention research examining two related topics, i.e., methodological issues and research integrity, and challenges in the transfer of research knowledge into practice and policy. The main aims are to identify how to advance methodology in order to improve research quality, examine scientific integrity in the field of intervention science, and discuss future steps to enhance the transfer of knowledge about evidence-based intervention principles into sustained practice, routine activities, and policy decisions. Themes of the special issue are twofold. The first includes questions about research methodology in intervention science, both in terms of research design and methods, as well as data analyses and the reporting of findings. Second, the issue tackles questions surrounding the types of knowledge translation frameworks that might be beneficial to mobilize the transfer of research-based knowledge into practice and public policies. The issue argues that innovations in methodology and thoughtful approaches to knowledge translation can enable transparency, quality, and sustainability of intervention research.

Understanding Emergency Care Delivery Through Computer Simulation Modeling.

PubMed

Laker, Lauren F; Torabi, Elham; France, Daniel J; Froehle, Craig M; Goldlust, Eric J; Hoot, Nathan R; Kasaie, Parastu; Lyons, Michael S; Barg-Walkow, Laura H; Ward, Michael J; Wears, Robert L

2018-02-01

In 2017, Academic Emergency Medicine convened a consensus conference entitled, "Catalyzing System Change through Health Care Simulation: Systems, Competency, and Outcomes." This article, a product of the breakout session on "understanding complex interactions through systems modeling," explores the role that computer simulation modeling can and should play in research and development of emergency care delivery systems. This article discusses areas central to the use of computer simulation modeling in emergency care research. The four central approaches to computer simulation modeling are described (Monte Carlo simulation, system dynamics modeling, discrete-event simulation, and agent-based simulation), along with problems amenable to their use and relevant examples to emergency care. Also discussed is an introduction to available software modeling platforms and how to explore their use for research, along with a research agenda for computer simulation modeling. Through this article, our goal is to enhance adoption of computer simulation, a set of methods that hold great promise in addressing emergency care organization and design challenges. © 2017 by the Society for Academic Emergency Medicine.

DMA Modern Programming Environment Study.

DTIC Science & Technology

1980-01-01

capabilities. The centers are becoming increasingly dependent upon the computer and digital data in the fulfillment of MC&G goals. Successful application...ftticrcsrccessors C140 by Herbert AlteroDigital Citmmuncaticns C141 0 Structuredl Design ’-:orkshocr by Ned Chapin KC 156o Digital Systems En17lrceriirg CC 139 o3...on a programming environment. The study, which resulted in production of a paper entitled An EXEC 8 Programming Support Libary , contends that most of

Ethics across the computer science curriculum: privacy modules in an introductory database course.

PubMed

Appel, Florence

2005-10-01

This paper describes the author's experience of infusing an introductory database course with privacy content, and the on-going project entitled Integrating Ethics Into the Database Curriculum, that evolved from that experience. The project, which has received funding from the National Science Foundation, involves the creation of a set of privacy modules that can be implemented systematically by database educators throughout the database design thread of an undergraduate course.

MIT Laboratory for Computer Science Progress Report 20 - July 1982 - Jun 1983,

DTIC Science & Technology

1984-07-01

system by the Programming Technology Group. Research in the second and largest area entitled Machines, Languages , and Systems, strives to discover and...utilization and cost effectiveness . For example, the Programming Methodology Group and the Real Time Systems Group are developing languages and...100 Megabits per second when implemented with the 1.2[im. n- well cMOS process. 3. LANGUAGES 3.1. Demand Driven Evaluation In his engineer’s thesis

Modeling Ni-Cd performance. Planned alterations to the Goddard battery model

NASA Technical Reports Server (NTRS)

Jagielski, J. M.

1986-01-01

The Goddard Space Flight Center (GSFC) currently has a preliminary computer model to simulate a Nickel Cadmium (Ni-Cd) performance. The basic methodology of the model was described in the paper entitled Fundamental Algorithms of the Goddard Battery Model. At present, the model is undergoing alterations to increase its efficiency, accuracy, and generality. A review of the present battery model is given, and the planned charges of the model are described.

A Business Case Analysis of the Direct Health Care Provider Program Womack Army Medical Center, Fort Bragg, N.C.

DTIC Science & Technology

2001-05-01

Unspecified (959.01) Hypovolemia (276.5) Medicine Headache, Migraine Variant (346.20) Infectious Mononucleosis (075) Alcohol Abuse, Unspecified (305.00...under the FTCA. In an article entitled “Can the Feres Doctrine Survive TRICARE, and Should It?”, the author examines issues that complicate the...Enteritis – Infectious (009.1) Irritable Bowel Syndrome (564.1) Epilepsy NOS (345.90) Herpes Simplex, NOS (054.9) Ulcerative Colitis (556.9) Head Injury

Vaccines for Children: Critical Issues in Design and Implementation. Report to Congressional Requesters [and] Vaccines for Children: Major Implementation Hurdles Remain. Testimony of Kwai-Cheung Chan, before the Subcommittee on Labor, Health, Human Services, and Education, Committee on Appropriations, United States Senate.

ERIC Educational Resources Information Center

General Accounting Office, Washington, DC. Program Evaluation and Methodology Div.

In response to congressional request, this report provides information on the implementation plans developed by the Center for Disease Control (CDC) for the Vaccines for Children (VFC) Program. Introductory material indicates that the VFC was created to increase vaccine coverage levels nationwide by creating an entitlement to free vaccine for…

Publications on acoustics research at the Langley Research Center during 1980-1986

NASA Technical Reports Server (NTRS)

Sutherland, Linda W. (Compiler)

1988-01-01

This report is a compilation of publications from acoustics research at the Langley Research Center. The reports are listed in chronological order and summarize the written output of the Acoustics Division and its predecessor, The Acoustics and Noise Reduction Division, for the period 1980 through 1986. The information assembled has been extracted from the 1980 through 1986 issues for the Technical Memorandum entitled, Scientific and Technical Information Output of the Langley Research Center for the Calendar Year.

The association between LEPR Q223R polymorphisms and breast cancer risk.

PubMed

Wang, Yadong; Yang, Haiyan; Gao, Huiyan; Wang, Haiyu

2015-05-01

Recently, we have read with great interest the article entitled "The association between polymorphisms in the leptin receptor (LEPR) gene and risk of breast cancer: a systematic review and pooled analysis" published online by Wang et al. (Breast Cancer Res Treat 136:231-239, 2012). This article suggests that the A allele of LEPR gene rs1137101 variant was low-penetrant risk factor for developing breast cancer. The result is encouraging. Nevertheless, several key issues are worth noticing.

An Alternative Approach to ``Measuring Horsepower and Torque Curves of a Car''

NASA Astrophysics Data System (ADS)

Graney, Chris M.

2005-09-01

The article in the September 2003 issue of TPT by John Ross Buschert of Goshen College entitled "Measuring Horsepower and Torque Curves of a Car" was excellent. I attained similar results using existing automobile test data. Automobile performance tests done by magazines such as Road & Track are a treasure trove of good-quality physics data. Performance tests often contain all the data needed to replicate Professor Buschert's analysis of the power and torque output of automobile engines.

78 FR 79479 - Notice of Receipt of Complaint; Solicitation of Comments Relating to the Public Interest

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-30

...Notice is hereby given that the U.S. International Trade Commission has received a complaint entitled Certain Standard Cell Libraries, Products Containing or Made Using the Same, Integrated Circuits Made Using the Same, and Products Containing Such Integrated Circuits, DN 2994; the Commission is soliciting comments on any public interest issues raised by the complaint or complainant's filing under section 210.8(b) of the Commission's Rules of Practice and Procedure (19 CFR 210.8(b)).

A Study of Transparent Plastics for use on Aircraft. Supplement

NASA Technical Reports Server (NTRS)

Axilrod, Benjamin M.; Kline, Gordon M.

1937-01-01

This supplement to a NACA study issued in May 1937 entitled "A Study of Transparent Plastics for Use on Aircraft", contains two tables. These tables contain data on bursting strengths of plastics, particularly at low temperatures. Table 1 contains the values reported in a table of the original memorandum, and additional values obtained at approximately 25 C, for three samples of Acrylate resin. The second table contains data obtained for the bursting strength when one surface of the plastic was cooled to approximately -35 C.

Responsible authorship in engineering fields: an overview of current ethical challenges.

PubMed

Borenstein, Jason

2011-06-01

The primary aim of this article is to identify ethical challenges relating to authorship in engineering fields. Professional organizations and journals do provide crucial guidance in this realm, but this cannot replace the need for frequent and diligent discussions in engineering research communities about what constitutes appropriate authorship practice. Engineering researchers should seek to identify and address issues such as who is entitled to be an author and whether publishing their research could potentially harm the public.