Sample records for jacobi-davidson type methods

  1. Efficient Jacobi-Gauss collocation method for solving initial value problems of Bratu type

    NASA Astrophysics Data System (ADS)

    Doha, E. H.; Bhrawy, A. H.; Baleanu, D.; Hafez, R. M.

    2013-09-01

    In this paper, we propose the shifted Jacobi-Gauss collocation spectral method for solving initial value problems of Bratu type, which is widely applicable in fuel ignition of the combustion theory and heat transfer. The spatial approximation is based on shifted Jacobi polynomials J {/n (α,β)}( x) with α, β ∈ (-1, ∞), x ∈ [0, 1] and n the polynomial degree. The shifted Jacobi-Gauss points are used as collocation nodes. Illustrative examples have been discussed to demonstrate the validity and applicability of the proposed technique. Comparing the numerical results of the proposed method with some well-known results show that the method is efficient and gives excellent numerical results.

  2. Convergence to Diagonal Form of Block Jacobi-type Processes

    NASA Astrophysics Data System (ADS)

    Hari, Vjeran

    2008-09-01

    The main result of recent research on convergence to diagonal form of block Jacobi-type processes is presented. For this purpose, all notions needed to describe the result are introduced. In particular, elementary block transformation matrices, simple and non-simple algorithms, block pivot strategies together with the appropriate equivalence relations are defined. The general block Jacobi-type process considered here can be specialized to take the form of almost any known Jacobi-type method for solving the ordinary or the generalized matrix eigenvalue and singular value problems. The assumptions used in the result are satisfied by many concrete methods.

  3. New formulae between Jacobi polynomials and some fractional Jacobi functions generalizing some connection formulae

    NASA Astrophysics Data System (ADS)

    Abd-Elhameed, W. M.

    2017-07-01

    In this paper, a new formula relating Jacobi polynomials of arbitrary parameters with the squares of certain fractional Jacobi functions is derived. The derived formula is expressed in terms of a certain terminating hypergeometric function of the type _4F3(1) . With the aid of some standard reduction formulae such as Pfaff-Saalschütz's and Watson's identities, the derived formula can be reduced in simple forms which are free of any hypergeometric functions for certain choices of the involved parameters of the Jacobi polynomials and the Jacobi functions. Some other simplified formulae are obtained via employing some computer algebra algorithms such as the algorithms of Zeilberger, Petkovsek and van Hoeij. Some connection formulae between some Jacobi polynomials are deduced. From these connection formulae, some other linearization formulae of Chebyshev polynomials are obtained. As an application to some of the introduced formulae, a numerical algorithm for solving nonlinear Riccati differential equation is presented and implemented by applying a suitable spectral method.

  4. A robust variant of block Jacobi-Davidson for extracting a large number of eigenpairs: Application to grid-based real-space density functional theory

    NASA Astrophysics Data System (ADS)

    Lee, M.; Leiter, K.; Eisner, C.; Breuer, A.; Wang, X.

    2017-09-01

    In this work, we investigate a block Jacobi-Davidson (J-D) variant suitable for sparse symmetric eigenproblems where a substantial number of extremal eigenvalues are desired (e.g., ground-state real-space quantum chemistry). Most J-D algorithm variations tend to slow down as the number of desired eigenpairs increases due to frequent orthogonalization against a growing list of solved eigenvectors. In our specification of block J-D, all of the steps of the algorithm are performed in clusters, including the linear solves, which allows us to greatly reduce computational effort with blocked matrix-vector multiplies. In addition, we move orthogonalization against locked eigenvectors and working eigenvectors outside of the inner loop but retain the single Ritz vector projection corresponding to the index of the correction vector. Furthermore, we minimize the computational effort by constraining the working subspace to the current vectors being updated and the latest set of corresponding correction vectors. Finally, we incorporate accuracy thresholds based on the precision required by the Fermi-Dirac distribution. The net result is a significant reduction in the computational effort against most previous block J-D implementations, especially as the number of wanted eigenpairs grows. We compare our approach with another robust implementation of block J-D (JDQMR) and the state-of-the-art Chebyshev filter subspace (CheFSI) method for various real-space density functional theory systems. Versus CheFSI, for first-row elements, our method yields competitive timings for valence-only systems and 4-6× speedups for all-electron systems with up to 10× reduced matrix-vector multiplies. For all-electron calculations on larger elements (e.g., gold) where the wanted spectrum is quite narrow compared to the full spectrum, we observe 60× speedup with 200× fewer matrix-vector multiples vs. CheFSI.

  5. A robust variant of block Jacobi-Davidson for extracting a large number of eigenpairs: Application to grid-based real-space density functional theory.

    PubMed

    Lee, M; Leiter, K; Eisner, C; Breuer, A; Wang, X

    2017-09-21

    In this work, we investigate a block Jacobi-Davidson (J-D) variant suitable for sparse symmetric eigenproblems where a substantial number of extremal eigenvalues are desired (e.g., ground-state real-space quantum chemistry). Most J-D algorithm variations tend to slow down as the number of desired eigenpairs increases due to frequent orthogonalization against a growing list of solved eigenvectors. In our specification of block J-D, all of the steps of the algorithm are performed in clusters, including the linear solves, which allows us to greatly reduce computational effort with blocked matrix-vector multiplies. In addition, we move orthogonalization against locked eigenvectors and working eigenvectors outside of the inner loop but retain the single Ritz vector projection corresponding to the index of the correction vector. Furthermore, we minimize the computational effort by constraining the working subspace to the current vectors being updated and the latest set of corresponding correction vectors. Finally, we incorporate accuracy thresholds based on the precision required by the Fermi-Dirac distribution. The net result is a significant reduction in the computational effort against most previous block J-D implementations, especially as the number of wanted eigenpairs grows. We compare our approach with another robust implementation of block J-D (JDQMR) and the state-of-the-art Chebyshev filter subspace (CheFSI) method for various real-space density functional theory systems. Versus CheFSI, for first-row elements, our method yields competitive timings for valence-only systems and 4-6× speedups for all-electron systems with up to 10× reduced matrix-vector multiplies. For all-electron calculations on larger elements (e.g., gold) where the wanted spectrum is quite narrow compared to the full spectrum, we observe 60× speedup with 200× fewer matrix-vector multiples vs. CheFSI.

  6. A shifted Jacobi collocation algorithm for wave type equations with non-local conservation conditions

    NASA Astrophysics Data System (ADS)

    Doha, Eid H.; Bhrawy, Ali H.; Abdelkawy, Mohammed A.

    2014-09-01

    In this paper, we propose an efficient spectral collocation algorithm to solve numerically wave type equations subject to initial, boundary and non-local conservation conditions. The shifted Jacobi pseudospectral approximation is investigated for the discretization of the spatial variable of such equations. It possesses spectral accuracy in the spatial variable. The shifted Jacobi-Gauss-Lobatto (SJ-GL) quadrature rule is established for treating the non-local conservation conditions, and then the problem with its initial and non-local boundary conditions are reduced to a system of second-order ordinary differential equations in temporal variable. This system is solved by two-stage forth-order A-stable implicit RK scheme. Five numerical examples with comparisons are given. The computational results demonstrate that the proposed algorithm is more accurate than finite difference method, method of lines and spline collocation approach

  7. On shifted Jacobi spectral method for high-order multi-point boundary value problems

    NASA Astrophysics Data System (ADS)

    Doha, E. H.; Bhrawy, A. H.; Hafez, R. M.

    2012-10-01

    This paper reports a spectral tau method for numerically solving multi-point boundary value problems (BVPs) of linear high-order ordinary differential equations. The construction of the shifted Jacobi tau approximation is based on conventional differentiation. This use of differentiation allows the imposition of the governing equation at the whole set of grid points and the straight forward implementation of multiple boundary conditions. Extension of the tau method for high-order multi-point BVPs with variable coefficients is treated using the shifted Jacobi Gauss-Lobatto quadrature. Shifted Jacobi collocation method is developed for solving nonlinear high-order multi-point BVPs. The performance of the proposed methods is investigated by considering several examples. Accurate results and high convergence rates are achieved.

  8. Local, smooth, and consistent Jacobi set simplification

    DOE PAGES

    Bhatia, Harsh; Wang, Bei; Norgard, Gregory; ...

    2014-10-31

    The relation between two Morse functions defined on a smooth, compact, and orientable 2-manifold can be studied in terms of their Jacobi set. The Jacobi set contains points in the domain where the gradients of the two functions are aligned. Both the Jacobi set itself as well as the segmentation of the domain it induces, have shown to be useful in various applications. In practice, unfortunately, functions often contain noise and discretization artifacts, causing their Jacobi set to become unmanageably large and complex. Although there exist techniques to simplify Jacobi sets, they are unsuitable for most applications as they lackmore » fine-grained control over the process, and heavily restrict the type of simplifications possible. In this paper, we introduce a new framework that generalizes critical point cancellations in scalar functions to Jacobi set in two dimensions. We present a new interpretation of Jacobi set simplification based on the perspective of domain segmentation. Generalizing the cancellation of critical points from scalar functions to Jacobi sets, we focus on simplifications that can be realized by smooth approximations of the corresponding functions, and show how these cancellations imply simultaneous simplification of contiguous subsets of the Jacobi set. Using these extended cancellations as atomic operations, we introduce an algorithm to successively cancel subsets of the Jacobi set with minimal modifications to some user-defined metric. We show that for simply connected domains, our algorithm reduces a given Jacobi set to its minimal configuration, that is, one with no birth–death points (a birth–death point is a specific type of singularity within the Jacobi set where the level sets of the two functions and the Jacobi set have a common normal direction).« less

  9. Anderson acceleration of the Jacobi iterative method: An efficient alternative to Krylov methods for large, sparse linear systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pratapa, Phanisri P.; Suryanarayana, Phanish; Pask, John E.

    We employ Anderson extrapolation to accelerate the classical Jacobi iterative method for large, sparse linear systems. Specifically, we utilize extrapolation at periodic intervals within the Jacobi iteration to develop the Alternating Anderson–Jacobi (AAJ) method. We verify the accuracy and efficacy of AAJ in a range of test cases, including nonsymmetric systems of equations. We demonstrate that AAJ possesses a favorable scaling with system size that is accompanied by a small prefactor, even in the absence of a preconditioner. In particular, we show that AAJ is able to accelerate the classical Jacobi iteration by over four orders of magnitude, with speed-upsmore » that increase as the system gets larger. Moreover, we find that AAJ significantly outperforms the Generalized Minimal Residual (GMRES) method in the range of problems considered here, with the relative performance again improving with size of the system. As a result, the proposed method represents a simple yet efficient technique that is particularly attractive for large-scale parallel solutions of linear systems of equations.« less

  10. Anderson acceleration of the Jacobi iterative method: An efficient alternative to Krylov methods for large, sparse linear systems

    DOE PAGES

    Pratapa, Phanisri P.; Suryanarayana, Phanish; Pask, John E.

    2015-12-01

    We employ Anderson extrapolation to accelerate the classical Jacobi iterative method for large, sparse linear systems. Specifically, we utilize extrapolation at periodic intervals within the Jacobi iteration to develop the Alternating Anderson–Jacobi (AAJ) method. We verify the accuracy and efficacy of AAJ in a range of test cases, including nonsymmetric systems of equations. We demonstrate that AAJ possesses a favorable scaling with system size that is accompanied by a small prefactor, even in the absence of a preconditioner. In particular, we show that AAJ is able to accelerate the classical Jacobi iteration by over four orders of magnitude, with speed-upsmore » that increase as the system gets larger. Moreover, we find that AAJ significantly outperforms the Generalized Minimal Residual (GMRES) method in the range of problems considered here, with the relative performance again improving with size of the system. As a result, the proposed method represents a simple yet efficient technique that is particularly attractive for large-scale parallel solutions of linear systems of equations.« less

  11. Jacobi-Gauss-Lobatto collocation method for the numerical solution of 1+1 nonlinear Schrödinger equations

    NASA Astrophysics Data System (ADS)

    Doha, E. H.; Bhrawy, A. H.; Abdelkawy, M. A.; Van Gorder, Robert A.

    2014-03-01

    A Jacobi-Gauss-Lobatto collocation (J-GL-C) method, used in combination with the implicit Runge-Kutta method of fourth order, is proposed as a numerical algorithm for the approximation of solutions to nonlinear Schrödinger equations (NLSE) with initial-boundary data in 1+1 dimensions. Our procedure is implemented in two successive steps. In the first one, the J-GL-C is employed for approximating the functional dependence on the spatial variable, using (N-1) nodes of the Jacobi-Gauss-Lobatto interpolation which depends upon two general Jacobi parameters. The resulting equations together with the two-point boundary conditions induce a system of 2(N-1) first-order ordinary differential equations (ODEs) in time. In the second step, the implicit Runge-Kutta method of fourth order is applied to solve this temporal system. The proposed J-GL-C method, used in combination with the implicit Runge-Kutta method of fourth order, is employed to obtain highly accurate numerical approximations to four types of NLSE, including the attractive and repulsive NLSE and a Gross-Pitaevskii equation with space-periodic potential. The numerical results obtained by this algorithm have been compared with various exact solutions in order to demonstrate the accuracy and efficiency of the proposed method. Indeed, for relatively few nodes used, the absolute error in our numerical solutions is sufficiently small.

  12. A Discontinuous Galerkin Finite Element Method for Hamilton-Jacobi Equations

    NASA Technical Reports Server (NTRS)

    Hu, Changqing; Shu, Chi-Wang

    1998-01-01

    In this paper, we present a discontinuous Galerkin finite element method for solving the nonlinear Hamilton-Jacobi equations. This method is based on the Runge-Kutta discontinuous Galerkin finite element method for solving conservation laws. The method has the flexibility of treating complicated geometry by using arbitrary triangulation, can achieve high order accuracy with a local, compact stencil, and are suited for efficient parallel implementation. One and two dimensional numerical examples are given to illustrate the capability of the method.

  13. Scheduled Relaxation Jacobi method: Improvements and applications

    NASA Astrophysics Data System (ADS)

    Adsuara, J. E.; Cordero-Carrión, I.; Cerdá-Durán, P.; Aloy, M. A.

    2016-09-01

    Elliptic partial differential equations (ePDEs) appear in a wide variety of areas of mathematics, physics and engineering. Typically, ePDEs must be solved numerically, which sets an ever growing demand for efficient and highly parallel algorithms to tackle their computational solution. The Scheduled Relaxation Jacobi (SRJ) is a promising class of methods, atypical for combining simplicity and efficiency, that has been recently introduced for solving linear Poisson-like ePDEs. The SRJ methodology relies on computing the appropriate parameters of a multilevel approach with the goal of minimizing the number of iterations needed to cut down the residuals below specified tolerances. The efficiency in the reduction of the residual increases with the number of levels employed in the algorithm. Applying the original methodology to compute the algorithm parameters with more than 5 levels notably hinders obtaining optimal SRJ schemes, as the mixed (non-linear) algebraic-differential system of equations from which they result becomes notably stiff. Here we present a new methodology for obtaining the parameters of SRJ schemes that overcomes the limitations of the original algorithm and provide parameters for SRJ schemes with up to 15 levels and resolutions of up to 215 points per dimension, allowing for acceleration factors larger than several hundreds with respect to the Jacobi method for typical resolutions and, in some high resolution cases, close to 1000. Most of the success in finding SRJ optimal schemes with more than 10 levels is based on an analytic reduction of the complexity of the previously mentioned system of equations. Furthermore, we extend the original algorithm to apply it to certain systems of non-linear ePDEs.

  14. A method based on the Jacobi tau approximation for solving multi-term time-space fractional partial differential equations

    NASA Astrophysics Data System (ADS)

    Bhrawy, A. H.; Zaky, M. A.

    2015-01-01

    In this paper, we propose and analyze an efficient operational formulation of spectral tau method for multi-term time-space fractional differential equation with Dirichlet boundary conditions. The shifted Jacobi operational matrices of Riemann-Liouville fractional integral, left-sided and right-sided Caputo fractional derivatives are presented. By using these operational matrices, we propose a shifted Jacobi tau method for both temporal and spatial discretizations, which allows us to present an efficient spectral method for solving such problem. Furthermore, the error is estimated and the proposed method has reasonable convergence rates in spatial and temporal discretizations. In addition, some known spectral tau approximations can be derived as special cases from our algorithm if we suitably choose the corresponding special cases of Jacobi parameters θ and ϑ. Finally, in order to demonstrate its accuracy, we compare our method with those reported in the literature.

  15. Lax-Friedrichs sweeping scheme for static Hamilton-Jacobi equations

    NASA Astrophysics Data System (ADS)

    Kao, Chiu Yen; Osher, Stanley; Qian, Jianliang

    2004-05-01

    We propose a simple, fast sweeping method based on the Lax-Friedrichs monotone numerical Hamiltonian to approximate viscosity solutions of arbitrary static Hamilton-Jacobi equations in any number of spatial dimensions. By using the Lax-Friedrichs numerical Hamiltonian, we can easily obtain the solution at a specific grid point in terms of its neighbors, so that a Gauss-Seidel type nonlinear iterative method can be utilized. Furthermore, by incorporating a group-wise causality principle into the Gauss-Seidel iteration by following a finite group of characteristics, we have an easy-to-implement, sweeping-type, and fast convergent numerical method. However, unlike other methods based on the Godunov numerical Hamiltonian, some computational boundary conditions are needed in the implementation. We give a simple recipe which enforces a version of discrete min-max principle. Some convergence analysis is done for the one-dimensional eikonal equation. Extensive 2-D and 3-D numerical examples illustrate the efficiency and accuracy of the new approach. To our knowledge, this is the first fast numerical method based on discretizing the Hamilton-Jacobi equation directly without assuming convexity and/or homogeneity of the Hamiltonian.

  16. Eric Davidson and deep time.

    PubMed

    Erwin, Douglas H

    2017-10-13

    Eric Davidson had a deep and abiding interest in the role developmental mechanisms played in generating evolutionary patterns documented in deep time, from the origin of the euechinoids to the processes responsible for the morphological architectures of major animal clades. Although not an evolutionary biologist, Davidson's interests long preceded the current excitement over comparative evolutionary developmental biology. Here I discuss three aspects at the intersection between his research and evolutionary patterns in deep time: First, understanding the mechanisms of body plan formation, particularly those associated with the early diversification of major metazoan clades. Second, a critique of early claims about ancestral metazoans based on the discoveries of highly conserved genes across bilaterian animals. Third, Davidson's own involvement in paleontology through a collaborative study of the fossil embryos from the Ediacaran Doushantuo Formation in south China.

  17. Eric Davidson, his philosophy, and the history of science.

    PubMed

    Deichmann, Ute

    2017-10-16

    Eric Davidson, a passionate molecular developmental biologist and intellectual, believed that conceptual advances in the sciences should be based on knowledge of conceptual history. Convinced of the superiority of a causal-analytical approach over other methods, he succeeded in successfully applying this approach to the complex feature of organismal development by introducing the far-reaching concept of developmental Gene Regulatory Networks. This essay reviews Davidson's philosophy, his support for the history of science, and some aspects of his scientific personality.

  18. Language Learning in Wittgenstein and Davidson

    ERIC Educational Resources Information Center

    Kotzee, Ben

    2014-01-01

    In this paper, I discuss language learning in Wittgenstein and Davidson. Starting from a remark by Bakhurst, I hold that both Wittgenstein and Davidson's philosophies of language contain responses to the problem of language learning, albeit of a different form. Following Williams, I hold that the concept of language learning can explain…

  19. Jacobi spectral Galerkin method for elliptic Neumann problems

    NASA Astrophysics Data System (ADS)

    Doha, E.; Bhrawy, A.; Abd-Elhameed, W.

    2009-01-01

    This paper is concerned with fast spectral-Galerkin Jacobi algorithms for solving one- and two-dimensional elliptic equations with homogeneous and nonhomogeneous Neumann boundary conditions. The paper extends the algorithms proposed by Shen (SIAM J Sci Comput 15:1489-1505, 1994) and Auteri et al. (J Comput Phys 185:427-444, 2003), based on Legendre polynomials, to Jacobi polynomials with arbitrary α and β. The key to the efficiency of our algorithms is to construct appropriate basis functions with zero slope at the endpoints, which lead to systems with sparse matrices for the discrete variational formulations. The direct solution algorithm developed for the homogeneous Neumann problem in two-dimensions relies upon a tensor product process. Nonhomogeneous Neumann data are accounted for by means of a lifting. Numerical results indicating the high accuracy and effectiveness of these algorithms are presented.

  20. Cole-Davidson dynamics of simple chain models.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dotson, Taylor C.; McCoy, John Dwane; Adolf, Douglas Brian

    2008-10-01

    Rotational relaxation functions of the end-to-end vector of short, freely jointed and freely rotating chains were determined from molecular dynamics simulations. The associated response functions were obtained from the one-sided Fourier transform of the relaxation functions. The Cole-Davidson function was used to fit the response functions with extensive use being made of Cole-Cole plots in the fitting procedure. For the systems studied, the Cole-Davidson function provided remarkably accurate fits [as compared to the transform of the Kohlrausch-Williams-Watts (KWW) function]. The only appreciable deviations from the simulation results were in the high frequency limit and were due to ballistic or freemore » rotation effects. The accuracy of the Cole-Davidson function appears to be the result of the transition in the time domain from stretched exponential behavior at intermediate time to single exponential behavior at long time. Such a transition can be explained in terms of a distribution of relaxation times with a well-defined longest relaxation time. Since the Cole-Davidson distribution has a sharp cutoff in relaxation time (while the KWW function does not), it makes sense that the Cole-Davidson would provide a better frequency-domain description of the associated response function than the KWW function does.« less

  1. Efficient relaxed-Jacobi smoothers for multigrid on parallel computers

    NASA Astrophysics Data System (ADS)

    Yang, Xiang; Mittal, Rajat

    2017-03-01

    In this Technical Note, we present a family of Jacobi-based multigrid smoothers suitable for the solution of discretized elliptic equations. These smoothers are based on the idea of scheduled-relaxation Jacobi proposed recently by Yang & Mittal (2014) [18] and employ two or three successive relaxed Jacobi iterations with relaxation factors derived so as to maximize the smoothing property of these iterations. The performance of these new smoothers measured in terms of convergence acceleration and computational workload, is assessed for multi-domain implementations typical of parallelized solvers, and compared to the lexicographic point Gauss-Seidel smoother. The tests include the geometric multigrid method on structured grids as well as the algebraic grid method on unstructured grids. The tests demonstrate that unlike Gauss-Seidel, the convergence of these Jacobi-based smoothers is unaffected by domain decomposition, and furthermore, they outperform the lexicographic Gauss-Seidel by factors that increase with domain partition count.

  2. Hamilton-Jacobi theory in multisymplectic classical field theories

    NASA Astrophysics Data System (ADS)

    de León, Manuel; Prieto-Martínez, Pedro Daniel; Román-Roy, Narciso; Vilariño, Silvia

    2017-09-01

    The geometric framework for the Hamilton-Jacobi theory developed in the studies of Cariñena et al. [Int. J. Geom. Methods Mod. Phys. 3(7), 1417-1458 (2006)], Cariñena et al. [Int. J. Geom. Methods Mod. Phys. 13(2), 1650017 (2015)], and de León et al. [Variations, Geometry and Physics (Nova Science Publishers, New York, 2009)] is extended for multisymplectic first-order classical field theories. The Hamilton-Jacobi problem is stated for the Lagrangian and the Hamiltonian formalisms of these theories as a particular case of a more general problem, and the classical Hamilton-Jacobi equation for field theories is recovered from this geometrical setting. Particular and complete solutions to these problems are defined and characterized in several equivalent ways in both formalisms, and the equivalence between them is proved. The use of distributions in jet bundles that represent the solutions to the field equations is the fundamental tool in this formulation. Some examples are analyzed and, in particular, the Hamilton-Jacobi equation for non-autonomous mechanical systems is obtained as a special case of our results.

  3. Fisher's method of scoring in statistical image reconstruction: comparison of Jacobi and Gauss-Seidel iterative schemes.

    PubMed

    Hudson, H M; Ma, J; Green, P

    1994-01-01

    Many algorithms for medical image reconstruction adopt versions of the expectation-maximization (EM) algorithm. In this approach, parameter estimates are obtained which maximize a complete data likelihood or penalized likelihood, in each iteration. Implicitly (and sometimes explicitly) penalized algorithms require smoothing of the current reconstruction in the image domain as part of their iteration scheme. In this paper, we discuss alternatives to EM which adapt Fisher's method of scoring (FS) and other methods for direct maximization of the incomplete data likelihood. Jacobi and Gauss-Seidel methods for non-linear optimization provide efficient algorithms applying FS in tomography. One approach uses smoothed projection data in its iterations. We investigate the convergence of Jacobi and Gauss-Seidel algorithms with clinical tomographic projection data.

  4. High-Order Semi-Discrete Central-Upwind Schemes for Multi-Dimensional Hamilton-Jacobi Equations

    NASA Technical Reports Server (NTRS)

    Bryson, Steve; Levy, Doron; Biegel, Bryan (Technical Monitor)

    2002-01-01

    We present the first fifth order, semi-discrete central upwind method for approximating solutions of multi-dimensional Hamilton-Jacobi equations. Unlike most of the commonly used high order upwind schemes, our scheme is formulated as a Godunov-type scheme. The scheme is based on the fluxes of Kurganov-Tadmor and Kurganov-Tadmor-Petrova, and is derived for an arbitrary number of space dimensions. A theorem establishing the monotonicity of these fluxes is provided. The spacial discretization is based on a weighted essentially non-oscillatory reconstruction of the derivative. The accuracy and stability properties of our scheme are demonstrated in a variety of examples. A comparison between our method and other fifth-order schemes for Hamilton-Jacobi equations shows that our method exhibits smaller errors without any increase in the complexity of the computations.

  5. Application of shifted Jacobi pseudospectral method for solving (in)finite-horizon min-max optimal control problems with uncertainty

    NASA Astrophysics Data System (ADS)

    Nikooeinejad, Z.; Delavarkhalafi, A.; Heydari, M.

    2018-03-01

    The difficulty of solving the min-max optimal control problems (M-MOCPs) with uncertainty using generalised Euler-Lagrange equations is caused by the combination of split boundary conditions, nonlinear differential equations and the manner in which the final time is treated. In this investigation, the shifted Jacobi pseudospectral method (SJPM) as a numerical technique for solving two-point boundary value problems (TPBVPs) in M-MOCPs for several boundary states is proposed. At first, a novel framework of approximate solutions which satisfied the split boundary conditions automatically for various boundary states is presented. Then, by applying the generalised Euler-Lagrange equations and expanding the required approximate solutions as elements of shifted Jacobi polynomials, finding a solution of TPBVPs in nonlinear M-MOCPs with uncertainty is reduced to the solution of a system of algebraic equations. Moreover, the Jacobi polynomials are particularly useful for boundary value problems in unbounded domain, which allow us to solve infinite- as well as finite and free final time problems by domain truncation method. Some numerical examples are given to demonstrate the accuracy and efficiency of the proposed method. A comparative study between the proposed method and other existing methods shows that the SJPM is simple and accurate.

  6. Hybrid massively parallel fast sweeping method for static Hamilton-Jacobi equations

    NASA Astrophysics Data System (ADS)

    Detrixhe, Miles; Gibou, Frédéric

    2016-10-01

    The fast sweeping method is a popular algorithm for solving a variety of static Hamilton-Jacobi equations. Fast sweeping algorithms for parallel computing have been developed, but are severely limited. In this work, we present a multilevel, hybrid parallel algorithm that combines the desirable traits of two distinct parallel methods. The fine and coarse grained components of the algorithm take advantage of heterogeneous computer architecture common in high performance computing facilities. We present the algorithm and demonstrate its effectiveness on a set of example problems including optimal control, dynamic games, and seismic wave propagation. We give results for convergence, parallel scaling, and show state-of-the-art speedup values for the fast sweeping method.

  7. Compressed Semi-Discrete Central-Upwind Schemes for Hamilton-Jacobi Equations

    NASA Technical Reports Server (NTRS)

    Bryson, Steve; Kurganov, Alexander; Levy, Doron; Petrova, Guergana

    2003-01-01

    We introduce a new family of Godunov-type semi-discrete central schemes for multidimensional Hamilton-Jacobi equations. These schemes are a less dissipative generalization of the central-upwind schemes that have been recently proposed in series of works. We provide the details of the new family of methods in one, two, and three space dimensions, and then verify their expected low-dissipative property in a variety of examples.

  8. Hybrid massively parallel fast sweeping method for static Hamilton–Jacobi equations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Detrixhe, Miles, E-mail: mdetrixhe@engineering.ucsb.edu; University of California Santa Barbara, Santa Barbara, CA, 93106; Gibou, Frédéric, E-mail: fgibou@engineering.ucsb.edu

    The fast sweeping method is a popular algorithm for solving a variety of static Hamilton–Jacobi equations. Fast sweeping algorithms for parallel computing have been developed, but are severely limited. In this work, we present a multilevel, hybrid parallel algorithm that combines the desirable traits of two distinct parallel methods. The fine and coarse grained components of the algorithm take advantage of heterogeneous computer architecture common in high performance computing facilities. We present the algorithm and demonstrate its effectiveness on a set of example problems including optimal control, dynamic games, and seismic wave propagation. We give results for convergence, parallel scaling,more » and show state-of-the-art speedup values for the fast sweeping method.« less

  9. Fronts propagating with curvature dependent speed: Algorithms based on Hamilton-Jacobi formulations

    NASA Technical Reports Server (NTRS)

    Osher, Stanley; Sethian, James A.

    1987-01-01

    New numerical algorithms are devised (PSC algorithms) for following fronts propagating with curvature-dependent speed. The speed may be an arbitrary function of curvature, and the front can also be passively advected by an underlying flow. These algorithms approximate the equations of motion, which resemble Hamilton-Jacobi equations with parabolic right-hand-sides, by using techniques from the hyperbolic conservation laws. Non-oscillatory schemes of various orders of accuracy are used to solve the equations, providing methods that accurately capture the formation of sharp gradients and cusps in the moving fronts. The algorithms handle topological merging and breaking naturally, work in any number of space dimensions, and do not require that the moving surface be written as a function. The methods can be used also for more general Hamilton-Jacobi-type problems. The algorithms are demonstrated by computing the solution to a variety of surface motion problems.

  10. Consent Decree for Harley-Davidson

    EPA Pesticide Factsheets

    Harley-Davidson will also pay a $12 million civil penalty and spend $3 million on a project to mitigate air pollution through a project to replace conventional woodstoves with cleaner-burning stoves in local communities.

  11. The Correlated Jacobi and the Correlated Cauchy-Lorentz Ensembles

    NASA Astrophysics Data System (ADS)

    Wirtz, Tim; Waltner, Daniel; Kieburg, Mario; Kumar, Santosh

    2016-01-01

    We calculate the k-point generating function of the correlated Jacobi ensemble using supersymmetric methods. We use the result for complex matrices for k=1 to derive a closed-form expression for the eigenvalue density. For real matrices we obtain the density in terms of a twofold integral that we evaluate numerically. For both expressions we find agreement when comparing with Monte Carlo simulations. Relations between these quantities for the Jacobi and the Cauchy-Lorentz ensemble are derived.

  12. 2. PHOTOGRAPH TAKEN FROM NORTH SIDE OF DAVIDSON DITCH LOOKING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. PHOTOGRAPH TAKEN FROM NORTH SIDE OF DAVIDSON DITCH LOOKING SOUTH ALONG LENGTH OF FLUME--VEGETATION NOT REMOVED AS PER ALASKA DEPARTMENT OF TRANSPORTATION PERSONNEL. - Davidson Ditch Waste Water Weir, Mile 63 of Alaska's Steese Highway, Chatanika, Fairbanks North Star Borough, AK

  13. Structural aspects of Hamilton-Jacobi theory

    NASA Astrophysics Data System (ADS)

    Cariñena, J. F.; Gràcia, X.; Marmo, G.; Martínez, E.; Muñoz-Lecanda, M. C.; Román-Roy, N.

    2016-12-01

    In our previous papers [J. F. Cariñena, X. Gràcia, G. Marmo, E. Martínez, M. C. Muñoz-Lecanda and N. Román-Roy, Geometric Hamilton-Jacobi theory, Int. J. Geom. Meth. Mod. Phys. 3 (2006) 1417-1458; Geometric Hamilton-Jacobi theory for nonholonomic dynamical systems, Int. J. Geom. Meth. Mod. Phys. 7 (2010) 431-454] we showed that the Hamilton-Jacobi problem can be regarded as a way to describe a given dynamics on a phase space manifold in terms of a family of dynamics on a lower-dimensional manifold. We also showed how constants of the motion help to solve the Hamilton-Jacobi equation. Here we want to delve into this interpretation by considering the most general case: a dynamical system on a manifold that is described in terms of a family of dynamics (slicing vector fields) on lower-dimensional manifolds. We identify the relevant geometric structures that lead from this decomposition of the dynamics to the classical Hamilton-Jacobi theory, by considering special cases like fibered manifolds and Hamiltonian dynamics, in the symplectic framework and the Poisson one. We also show how a set of functions on a tangent bundle can determine a second-order dynamics for which they are constants of the motion.

  14. Multitasking the Davidson algorithm for the large, sparse eigenvalue problem

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Umar, V.M.; Fischer, C.F.

    1989-01-01

    The authors report how the Davidson algorithm, developed for handling the eigenvalue problem for large and sparse matrices arising in quantum chemistry, was modified for use in atomic structure calculations. To date these calculations have used traditional eigenvalue methods, which limit the range of feasible calculations because of their excessive memory requirements and unsatisfactory performance attributed to time-consuming and costly processing of zero valued elements. The replacement of a traditional matrix eigenvalue method by the Davidson algorithm reduced these limitations. Significant speedup was found, which varied with the size of the underlying problem and its sparsity. Furthermore, the range ofmore » matrix sizes that can be manipulated efficiently was expended by more than one order or magnitude. On the CRAY X-MP the code was vectorized and the importance of gather/scatter analyzed. A parallelized version of the algorithm obtained an additional 35% reduction in execution time. Speedup due to vectorization and concurrency was also measured on the Alliant FX/8.« less

  15. Structure and decays of nuclear three-body systems: The Gamow coupled-channel method in Jacobi coordinates

    NASA Astrophysics Data System (ADS)

    Wang, S. M.; Michel, N.; Nazarewicz, W.; Xu, F. R.

    2017-10-01

    Background: Weakly bound and unbound nuclear states appearing around particle thresholds are prototypical open quantum systems. Theories of such states must take into account configuration mixing effects in the presence of strong coupling to the particle continuum space. Purpose: To describe structure and decays of three-body systems, we developed a Gamow coupled-channel (GCC) approach in Jacobi coordinates by employing the complex-momentum formalism. We benchmarked the complex-energy Gamow shell model (GSM) against the new framework. Methods: The GCC formalism is expressed in Jacobi coordinates, so that the center-of-mass motion is automatically eliminated. To solve the coupled-channel equations, we use hyperspherical harmonics to describe the angular wave functions while the radial wave functions are expanded in the Berggren ensemble, which includes bound, scattering, and Gamow states. Results: We show that the GCC method is both accurate and robust. Its results for energies, decay widths, and nucleon-nucleon angular correlations are in good agreement with the GSM results. Conclusions: We have demonstrated that a three-body GSM formalism explicitly constructed in the cluster-orbital shell model coordinates provides results similar to those with a GCC framework expressed in Jacobi coordinates, provided that a large configuration space is employed. Our calculations for A =6 systems and 26O show that nucleon-nucleon angular correlations are sensitive to the valence-neutron interaction. The new GCC technique has many attractive features when applied to bound and unbound states of three-body systems: it is precise, is efficient, and can be extended by introducing a microscopic model of the core.

  16. New algorithms for solving third- and fifth-order two point boundary value problems based on nonsymmetric generalized Jacobi Petrov–Galerkin method

    PubMed Central

    Doha, E.H.; Abd-Elhameed, W.M.; Youssri, Y.H.

    2014-01-01

    Two families of certain nonsymmetric generalized Jacobi polynomials with negative integer indexes are employed for solving third- and fifth-order two point boundary value problems governed by homogeneous and nonhomogeneous boundary conditions using a dual Petrov–Galerkin method. The idea behind our method is to use trial functions satisfying the underlying boundary conditions of the differential equations and the test functions satisfying the dual boundary conditions. The resulting linear systems from the application of our method are specially structured and they can be efficiently inverted. The use of generalized Jacobi polynomials simplify the theoretical and numerical analysis of the method and also leads to accurate and efficient numerical algorithms. The presented numerical results indicate that the proposed numerical algorithms are reliable and very efficient. PMID:26425358

  17. Jacobi bundles and the BFV-complex

    NASA Astrophysics Data System (ADS)

    Lê, Hông Vân; Tortorella, Alfonso G.; Vitagliano, Luca

    2017-11-01

    We extend the construction of the BFV-complex of a coisotropic submanifold from the Poisson setting to the Jacobi setting. In particular, our construction applies in the contact and l.c.s. settings. The BFV-complex of a coisotropic submanifold S controls the coisotropic deformation problem of S under both Hamiltonian and Jacobi equivalence.

  18. A perspective on the contributions of Ronald C. Davidson to plasma physics

    NASA Astrophysics Data System (ADS)

    Wurtele, Jonathan S.

    2016-10-01

    Starting in the 1960s and continuing for half a century, Ronald C. Davidson made fundamental theoretical contributions to a wide range of areas of pure and applied plasma physics. Davidson was one of the founders of nonneutral plasma physics and a pioneer in developing and applying kinetic theory and nonlinear stability theorems to collective interaction processes and nonlinear dynamics of nonneutral plasmas and intense charged particle beams. His textbooks on nonneutral plasmas are the classic references for the field and educated generations of graduate students. Davidson was a strong advocate for applying the ideas of plasma theory to develop techniques that benefit other branches of science. For example, one of the major derivative fields enabled by nonneutral plasmas is the study of antimatter plasmas and the synthesis of antihydrogen. This talk will review a few highlights of Ronald Davidson's impact on plasma physics and related fields of science.

  19. A Jacobi collocation approximation for nonlinear coupled viscous Burgers' equation

    NASA Astrophysics Data System (ADS)

    Doha, Eid H.; Bhrawy, Ali H.; Abdelkawy, Mohamed A.; Hafez, Ramy M.

    2014-02-01

    This article presents a numerical approximation of the initial-boundary nonlinear coupled viscous Burgers' equation based on spectral methods. A Jacobi-Gauss-Lobatto collocation (J-GL-C) scheme in combination with the implicit Runge-Kutta-Nyström (IRKN) scheme are employed to obtain highly accurate approximations to the mentioned problem. This J-GL-C method, based on Jacobi polynomials and Gauss-Lobatto quadrature integration, reduces solving the nonlinear coupled viscous Burgers' equation to a system of nonlinear ordinary differential equation which is far easier to solve. The given examples show, by selecting relatively few J-GL-C points, the accuracy of the approximations and the utility of the approach over other analytical or numerical methods. The illustrative examples demonstrate the accuracy, efficiency, and versatility of the proposed algorithm.

  20. Higher order derivatives of R-Jacobi polynomials

    NASA Astrophysics Data System (ADS)

    Das, Sourav; Swaminathan, A.

    2016-06-01

    In this work, the R-Jacobi polynomials defined on the nonnegative real axis related to F-distribution are considered. Using their Sturm-Liouville system higher order derivatives are constructed. Orthogonality property of these higher ordered R-Jacobi polynomials are obtained besides their normal form, self-adjoint form and hypergeometric representation. Interesting results on the Interpolation formula and Gaussian quadrature formulae are obtained with numerical examples.

  1. 15 CFR Appendix F to Subpart M of... - Davidson Seamount Management Zone

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 15 Commerce and Foreign Trade 3 2011-01-01 2011-01-01 false Davidson Seamount Management Zone F Appendix F to Subpart M of Part 922 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign... Sanctuary Pt. 922, Subpt. M, App. F Appendix F to Subpart M of Part 922—Davidson Seamount Management Zone...

  2. Inverse resonance scattering for Jacobi operators

    NASA Astrophysics Data System (ADS)

    Korotyaev, E. L.

    2011-12-01

    The Jacobi operator ( Jf) n = a n-1 f n-1 + a n f n+1 + b n f n on ℤ with real finitely supported sequences ( a n - 1) n∈ℤ and ( b n ) n∈ℤ is considered. The inverse problem for two mappings (including their characterization): ( a n , b n , n ∈ ℤ) → {the zeros of the reflection coefficient} and ( a n , b n , n ∈ ℤ) → {the eigenvalues and the resonances} is solved. All Jacobi operators with the same eigenvalues and resonances are also described.

  3. Diagnostic accuracy of three scoring methods for the Davidson Trauma Scale among U.S. military veterans.

    PubMed

    McDonald, Scott D; Thompson, NiVonne L; Stratton, Kelcey J; Calhoun, Patrick S

    2014-03-01

    Self-report questionnaires are frequently used to identify PTSD among U.S. military personnel and Veterans. Two common scoring methods used to classify PTSD include: (1) a cut score threshold and (2) endorsement of PTSD symptoms meeting DSM-IV-TR symptom cluster criteria (SCM). A third method requiring a cut score in addition to SCM has been proposed, but has received little study. The current study examined the diagnostic accuracy of three scoring methods for the Davidson Trauma Scale (DTS) among 804 Afghanistan and Iraq war-era military Service Members and Veterans. Data were weighted to approximate the prevalence of PTSD and other Axis I disorders in VA primary care. As expected, adding a cut score criterion to SCM improved specificity and positive predictive power. However, a cut score of 68-72 provided optimal diagnostic accuracy. The utility of the DTS, the role of baseline prevalence, and recommendations for future research are discussed. Published by Elsevier Ltd.

  4. Local spectral properties of reflectionless Jacobi, CMV, and Schrödinger operators

    NASA Astrophysics Data System (ADS)

    Gesztesy, Fritz; Zinchenko, Maxim

    We prove that Jacobi, CMV, and Schrödinger operators, which are reflectionless on a homogeneous set E (in the sense of Carleson), under the assumption of a Blaschke-type condition on their discrete spectra accumulating at E, have purely absolutely continuous spectrum on E.

  5. John A. Davidson: Coccidologist, artist, teacher and naturalist

    USDA-ARS?s Scientific Manuscript database

    Dr. John Davidson was honored at the XIV International Symposium on Scale Insect Studies with the Career Achievement award for his outstanding research on scale insects, particularly armored scales. His contributions with colleagues and students include a comprehensive treatise on the economic armo...

  6. Psychometric Evaluation of the Connor-Davidson Resilience Scale (CD-RISC) Using Iranian Students

    ERIC Educational Resources Information Center

    Khoshouei, Mahdieh Sadat

    2009-01-01

    The purpose of this study was to evaluate the psychometric properties of the Persian version of the Connor-Davidson Resilience Scale (CD-RISC). The CD-RISC was completed by a sample of 323 Isfahan university students (168 females, 155 males) aged 19-34 years. A maximum likelihood method with an oblique solution resulted in four factors…

  7. Quantitative Compactness Estimates for Hamilton-Jacobi Equations

    NASA Astrophysics Data System (ADS)

    Ancona, Fabio; Cannarsa, Piermarco; Nguyen, Khai T.

    2016-02-01

    We study quantitative compactness estimates in {W^{1,1}_{loc}} for the map {S_t}, {t > 0} that is associated with the given initial data {u_0in Lip (R^N)} for the corresponding solution {S_t u_0} of a Hamilton-Jacobi equation u_t+Hbig(nabla_{x} ubig)=0, qquad t≥ 0,quad xinR^N, with a uniformly convex Hamiltonian {H=H(p)}. We provide upper and lower estimates of order {1/\\varepsilon^N} on the Kolmogorov {\\varepsilon}-entropy in {W^{1,1}} of the image through the map S t of sets of bounded, compactly supported initial data. Estimates of this type are inspired by a question posed by Lax (Course on Hyperbolic Systems of Conservation Laws. XXVII Scuola Estiva di Fisica Matematica, Ravello, 2002) within the context of conservation laws, and could provide a measure of the order of "resolution" of a numerical method implemented for this equation.

  8. On the construction of recurrence relations for the expansion and connection coefficients in series of Jacobi polynomials

    NASA Astrophysics Data System (ADS)

    Doha, E. H.

    2004-01-01

    Formulae expressing explicitly the Jacobi coefficients of a general-order derivative (integral) of an infinitely differentiable function in terms of its original expansion coefficients, and formulae for the derivatives (integrals) of Jacobi polynomials in terms of Jacobi polynomials themselves are stated. A formula for the Jacobi coefficients of the moments of one single Jacobi polynomial of certain degree is proved. Another formula for the Jacobi coefficients of the moments of a general-order derivative of an infinitely differentiable function in terms of its original expanded coefficients is also given. A simple approach in order to construct and solve recursively for the connection coefficients between Jacobi-Jacobi polynomials is described. Explicit formulae for these coefficients between ultraspherical and Jacobi polynomials are deduced, of which the Chebyshev polynomials of the first and second kinds and Legendre polynomials are important special cases. Two analytical formulae for the connection coefficients between Laguerre-Jacobi and Hermite-Jacobi are developed.

  9. Unified formalism for the generalized kth-order Hamilton-Jacobi problem

    NASA Astrophysics Data System (ADS)

    Colombo, Leonardo; de Léon, Manuel; Prieto-Martínez, Pedro Daniel; Román-Roy, Narciso

    2014-08-01

    The geometric formulation of the Hamilton-Jacobi theory enables us to generalize it to systems of higher-order ordinary differential equations. In this work we introduce the unified Lagrangian-Hamiltonian formalism for the geometric Hamilton-Jacobi theory on higher-order autonomous dynamical systems described by regular Lagrangian functions.

  10. Complex quantum Hamilton-Jacobi equation with Bohmian trajectories: Application to the photodissociation dynamics of NOCl

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chou, Chia-Chun, E-mail: ccchou@mx.nthu.edu.tw

    2014-03-14

    The complex quantum Hamilton-Jacobi equation-Bohmian trajectories (CQHJE-BT) method is introduced as a synthetic trajectory method for integrating the complex quantum Hamilton-Jacobi equation for the complex action function by propagating an ensemble of real-valued correlated Bohmian trajectories. Substituting the wave function expressed in exponential form in terms of the complex action into the time-dependent Schrödinger equation yields the complex quantum Hamilton-Jacobi equation. We transform this equation into the arbitrary Lagrangian-Eulerian version with the grid velocity matching the flow velocity of the probability fluid. The resulting equation describing the rate of change in the complex action transported along Bohmian trajectories is simultaneouslymore » integrated with the guidance equation for Bohmian trajectories, and the time-dependent wave function is readily synthesized. The spatial derivatives of the complex action required for the integration scheme are obtained by solving one moving least squares matrix equation. In addition, the method is applied to the photodissociation of NOCl. The photodissociation dynamics of NOCl can be accurately described by propagating a small ensemble of trajectories. This study demonstrates that the CQHJE-BT method combines the considerable advantages of both the real and the complex quantum trajectory methods previously developed for wave packet dynamics.« less

  11. The classical limit of minimal length uncertainty relation: revisit with the Hamilton-Jacobi method

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Guo, Xiaobo; Wang, Peng; Yang, Haitang, E-mail: guoxiaobo@swust.edu.cn, E-mail: pengw@scu.edu.cn, E-mail: hyanga@scu.edu.cn

    2016-05-01

    The existence of a minimum measurable length could deform not only the standard quantum mechanics but also classical physics. The effects of the minimal length on classical orbits of particles in a gravitation field have been investigated before, using the deformed Poisson bracket or Schwarzschild metric. In this paper, we first use the Hamilton-Jacobi method to derive the deformed equations of motion in the context of Newtonian mechanics and general relativity. We then employ them to study the precession of planetary orbits, deflection of light, and time delay in radar propagation. We also set limits on the deformation parameter bymore » comparing our results with the observational measurements. Finally, comparison with results from previous papers is given at the end of this paper.« less

  12. A Hamilton-Jacobi theory for implicit differential systems

    NASA Astrophysics Data System (ADS)

    Esen, Oǧul; de León, Manuel; Sardón, Cristina

    2018-02-01

    In this paper, we propose a geometric Hamilton-Jacobi theory for systems of implicit differential equations. In particular, we are interested in implicit Hamiltonian systems, described in terms of Lagrangian submanifolds of TT*Q generated by Morse families. The implicit character implies the nonexistence of a Hamiltonian function describing the dynamics. This fact is here amended by a generating family of Morse functions which plays the role of a Hamiltonian. A Hamilton-Jacobi equation is obtained with the aid of this generating family of functions. To conclude, we apply our results to singular Lagrangians by employing the construction of special symplectic structures.

  13. Bohr Hamiltonian for γ = 30° with Davidson potential

    NASA Astrophysics Data System (ADS)

    Yigitoglu, Ibrahim; Gokbulut, Melek

    2018-03-01

    A γ-rigid solution of the Bohr Hamiltonian for γ = 30° is constructed with the Davidson potential in the β part. This solution is going to be called Z(4)-D. The energy eigenvalues and wave functions are obtained by using the analytic method developed by Nikiforov and Uvarov. The calculated intraband and interband B(E2) transitions rates are presented and compared with the Z(4) model predictions. The staggering behavior in γ-bands is considered to search Z(4) -D candidate nuclei. A variational procedure is applied to demonstrate that the Z(4) model is a solution of the critical point at the shape phase transition from spherical to rigid triaxial rotor.

  14. A Penalty Method for the Numerical Solution of Hamilton-Jacobi-Bellman (HJB) Equations in Finance

    NASA Astrophysics Data System (ADS)

    Witte, J. H.; Reisinger, C.

    2010-09-01

    We present a simple and easy to implement method for the numerical solution of a rather general class of Hamilton-Jacobi-Bellman (HJB) equations. In many cases, the considered problems have only a viscosity solution, to which, fortunately, many intuitive (e.g. finite difference based) discretisations can be shown to converge. However, especially when using fully implicit time stepping schemes with their desireable stability properties, one is still faced with the considerable task of solving the resulting nonlinear discrete system. In this paper, we introduce a penalty method which approximates the nonlinear discrete system to an order of O(1/ρ), where ρ>0 is the penalty parameter, and we show that an iterative scheme can be used to solve the penalised discrete problem in finitely many steps. We include a number of examples from mathematical finance for which the described approach yields a rigorous numerical scheme and present numerical results.

  15. Effect of the refractive index on the hawking temperature: an application of the Hamilton-Jacobi method

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sakalli, I., E-mail: izzet.sakalli@emu.edu.tr; Mirekhtiary, S. F., E-mail: fatemeh.mirekhtiary@emu.edu.tr

    2013-10-15

    Hawking radiation of a non-asymptotically flat 4-dimensional spherically symmetric and static dilatonic black hole (BH) via the Hamilton-Jacobi (HJ) method is studied. In addition to the naive coordinates, we use four more different coordinate systems that are well-behaved at the horizon. Except for the isotropic coordinates, direct computation by the HJ method leads to the standard Hawking temperature for all coordinate systems. The isotropic coordinates allow extracting the index of refraction from the Fermat metric. It is explicitly shown that the index of refraction determines the value of the tunneling rate and its natural consequence, the Hawking temperature. The isotropicmore » coordinates in the conventional HJ method produce a wrong result for the temperature of the linear dilaton. Here, we explain how this discrepancy can be resolved by regularizing the integral possessing a pole at the horizon.« less

  16. MOC Efficiency Improvements Using a Jacobi Inscatter Approximation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stimpson, Shane; Collins, Benjamin; Kochunas, Brendan

    2016-08-31

    In recent weeks, attention has been given to resolving the convergence issues encountered with TCP 0 by trying a Jacobi (J) inscatter approach when group sweeping, where the inscatter source is constructed using the previous iteration flux. This is in contrast to a Gauss-Seidel (GS) approach, which has been the default to-date, where the scattering source uses the most up-to-date flux values. The former is consistent with CASMO, which has no issues with TCP 0 convergence. Testing this out on a variety of problems has demonstrated that the Jacobi approach does indeed provide substantially more stability, though can take moremore » outer iterations to converge. While this is not surprising, there are improvements that can be made to the MOC sweeper to capitalize on the Jacobi approximation and provide substantial speedup. For example, the loop over groups, which has traditionally been the outermost loop in MPACT, can be moved to the interior, avoiding duplicate modular ray trace and coarse ray trace setup (mapping coarse mesh surface indexes), which needs to be performed repeatedly when group is outermost.« less

  17. Generalized Lagrange Jacobi Gauss-Lobatto (GLJGL) Collocation Method for Solving Linear and Nonlinear Fokker-Planck Equations

    NASA Astrophysics Data System (ADS)

    Parand, K.; Latifi, S.; Moayeri, M. M.; Delkhosh, M.

    2018-05-01

    In this study, we have constructed a new numerical approach for solving the time-dependent linear and nonlinear Fokker-Planck equations. In fact, we have discretized the time variable with Crank-Nicolson method and for the space variable, a numerical method based on Generalized Lagrange Jacobi Gauss-Lobatto (GLJGL) collocation method is applied. It leads to in solving the equation in a series of time steps and at each time step, the problem is reduced to a problem consisting of a system of algebraic equations that greatly simplifies the problem. One can observe that the proposed method is simple and accurate. Indeed, one of its merits is that it is derivative-free and by proposing a formula for derivative matrices, the difficulty aroused in calculation is overcome, along with that it does not need to calculate the General Lagrange basis and matrices; they have Kronecker property. Linear and nonlinear Fokker-Planck equations are given as examples and the results amply demonstrate that the presented method is very valid, effective, reliable and does not require any restrictive assumptions for nonlinear terms.

  18. Hamilton-Jacobi formalism to warm inflationary scenario

    NASA Astrophysics Data System (ADS)

    Sayar, K.; Mohammadi, A.; Akhtari, L.; Saaidi, Kh.

    2017-01-01

    The Hamilton-Jacobi formalism as a powerful method is being utilized to reconsider the warm inflationary scenario, where the scalar field as the main component driving inflation interacts with other fields. Separating the context into strong and weak dissipative regimes, the goal is followed for two popular functions of Γ . Applying slow-rolling approximation, the required perturbation parameters are extracted and, by comparing to the latest Planck data, the free parameters are restricted. The possibility of producing an acceptable inflation is studied where the result shows that for all cases the model could successfully suggest the amplitude of scalar perturbation, scalar spectral index, its running, and the tensor-to-scalar ratio.

  19. Generalized Lagrangian Jacobi Gauss collocation method for solving unsteady isothermal gas through a micro-nano porous medium

    NASA Astrophysics Data System (ADS)

    Parand, Kourosh; Latifi, Sobhan; Delkhosh, Mehdi; Moayeri, Mohammad M.

    2018-01-01

    In the present paper, a new method based on the Generalized Lagrangian Jacobi Gauss (GLJG) collocation method is proposed. The nonlinear Kidder equation, which explains unsteady isothermal gas through a micro-nano porous medium, is a second-order two-point boundary value ordinary differential equation on the unbounded interval [0, ∞). Firstly, using the quasilinearization method, the equation is converted to a sequence of linear ordinary differential equations. Then, by using the GLJG collocation method, the problem is reduced to solving a system of algebraic equations. It must be mentioned that this equation is solved without domain truncation and variable changing. A comparison with some numerical solutions made and the obtained results indicate that the presented solution is highly accurate. The important value of the initial slope, y'(0), is obtained as -1.191790649719421734122828603800159364 for η = 0.5. Comparing to the best result obtained so far, it is accurate up to 36 decimal places.

  20. A spectral tau algorithm based on Jacobi operational matrix for numerical solution of time fractional diffusion-wave equations

    NASA Astrophysics Data System (ADS)

    Bhrawy, A. H.; Doha, E. H.; Baleanu, D.; Ezz-Eldien, S. S.

    2015-07-01

    In this paper, an efficient and accurate spectral numerical method is presented for solving second-, fourth-order fractional diffusion-wave equations and fractional wave equations with damping. The proposed method is based on Jacobi tau spectral procedure together with the Jacobi operational matrix for fractional integrals, described in the Riemann-Liouville sense. The main characteristic behind this approach is to reduce such problems to those of solving systems of algebraic equations in the unknown expansion coefficients of the sought-for spectral approximations. The validity and effectiveness of the method are demonstrated by solving five numerical examples. Numerical examples are presented in the form of tables and graphs to make comparisons with the results obtained by other methods and with the exact solutions more easier.

  1. Jacobi Shape Transitions Within the LSD Model and the Skyrme-Etf Approach

    NASA Astrophysics Data System (ADS)

    Bartel, Johann; Pomorski, Krzysztof

    The "Modified Funny-Hills parametrisation" is used together with the Lublin-Strasbourg Drop Model to evaluate the stability of rotating nuclei. The Jacobi transition into triaxial shapes is studied. By a comparison with selfconsistent semiclassical calculations in the framework of the Extended Thomas-Fermi method, the validity of the present approach is demonstrated and possible improvements are indicated.

  2. Hunting grounds for Jacobi transitions and hyperdeformations

    DOE PAGES

    Herskind, B.; Benzoni, G.; Wilson, J. N.; ...

    2003-04-01

    In recent attempts to search for exotic shapes, hyperdeformation (HD), and Jacobi transitions in Hf, Ba, Xe, Sn and Nd nuclei, ridge structures presumably originating from nuclei of very elongated shapes have been observed in 126Ba, with Gammasphere (GS) and in 126Xe, with Euroball-IV (EB-IV). After the promising results from GS, a second experiment in 126Ba followed at EB-IV, taking advantage of the use of the BGO Inner Ball (IB) for selecting the highest spins. The decay of the Giant Dipole Resonances (GDR) is also studied, and the analysis in progress. The Quasi-continuum transitions in the Jacobi region, show amore » significant decrease in energy for both 126Ba and 126Xe, compared to the Thomas-Fermi- and the LSD model predictions. Similar effects were recently found for other nuclei by Ward et al.« less

  3. Selected List of Materials. Sarah K. Davidson Family-Patient Library.

    ERIC Educational Resources Information Center

    Sanders, Susan, Comp.; Satterwhite, Betty, Comp.

    Designed as an aid for those wishing to establish pediatric health education resource centers for use by patients and their families, this bibliography lists selected holdings of the Sarah K. Davidson Family-Patient Library, which is located in the Strong Memorial Hospital of the University of Rochester, New York. It is noted that all…

  4. Numerical analysis for trajectory controllability of a coupled multi-order fractional delay differential system via the shifted Jacobi method

    NASA Astrophysics Data System (ADS)

    Priya, B. Ganesh; Muthukumar, P.

    2018-02-01

    This paper deals with the trajectory controllability for a class of multi-order fractional linear systems subject to a constant delay in state vector. The solution for the coupled fractional delay differential equation is established by the Mittag-Leffler function. The necessary and sufficient condition for the trajectory controllability is formulated and proved by the generalized Gronwall's inequality. The approximate trajectory for the proposed system is obtained through the shifted Jacobi operational matrix method. The numerical simulation of the approximate solution shows the theoretical results. Finally, some remarks and comments on the existing results of constrained controllability for the fractional dynamical system are also presented.

  5. Solving the Hamilton-Jacobi equation for general relativity

    NASA Astrophysics Data System (ADS)

    Parry, J.; Salopek, D. S.; Stewart, J. M.

    1994-03-01

    We demonstrate a systematic method for solving the Hamilton-Jacobi equation for general relativity with the inclusion of matter fields. The generating functional is expanded in a series of spatial gradients. Each term is manifestly invariant under reparametrizations of the spatial coordinates (``gauge invariant''). At each order we solve the Hamiltonian constraint using a conformal transformation of the three-metric as well as a line integral in superspace. This gives a recursion relation for the generating functional which then may be solved to arbitrary order simply by functionally differentiating previous orders. At fourth order in spatial gradients we demonstrate solutions for irrotational dust as well as for a scalar field. We explicitly evolve the three-metric to the same order. This method can be used to derive the Zel'dovich approximation for general relativity.

  6. Gauss Seidel-type methods for energy states of a multi-component Bose Einstein condensate

    NASA Astrophysics Data System (ADS)

    Chang, Shu-Ming; Lin, Wen-Wei; Shieh, Shih-Feng

    2005-01-01

    In this paper, we propose two iterative methods, a Jacobi-type iteration (JI) and a Gauss-Seidel-type iteration (GSI), for the computation of energy states of the time-independent vector Gross-Pitaevskii equation (VGPE) which describes a multi-component Bose-Einstein condensate (BEC). A discretization of the VGPE leads to a nonlinear algebraic eigenvalue problem (NAEP). We prove that the GSI method converges locally and linearly to a solution of the NAEP if and only if the associated minimized energy functional problem has a strictly local minimum. The GSI method can thus be used to compute ground states and positive bound states, as well as the corresponding energies of a multi-component BEC. Numerical experience shows that the GSI converges much faster than JI and converges globally within 10-20 steps.

  7. Improvement of transport-corrected scattering stability and performance using a Jacobi inscatter algorithm for 2D-MOC

    DOE PAGES

    Stimpson, Shane; Collins, Benjamin; Kochunas, Brendan

    2017-03-10

    The MPACT code, being developed collaboratively by the University of Michigan and Oak Ridge National Laboratory, is the primary deterministic neutron transport solver being deployed within the Virtual Environment for Reactor Applications (VERA) as part of the Consortium for Advanced Simulation of Light Water Reactors (CASL). In many applications of the MPACT code, transport-corrected scattering has proven to be an obstacle in terms of stability, and considerable effort has been made to try to resolve the convergence issues that arise from it. Most of the convergence problems seem related to the transport-corrected cross sections, particularly when used in the 2Dmore » method of characteristics (MOC) solver, which is the focus of this work. Here in this paper, the stability and performance of the 2-D MOC solver in MPACT is evaluated for two iteration schemes: Gauss-Seidel and Jacobi. With the Gauss-Seidel approach, as the MOC solver loops over groups, it uses the flux solution from the previous group to construct the inscatter source for the next group. Alternatively, the Jacobi approach uses only the fluxes from the previous outer iteration to determine the inscatter source for each group. Consequently for the Jacobi iteration, the loop over groups can be moved from the outermost loop$-$as is the case with the Gauss-Seidel sweeper$-$to the innermost loop, allowing for a substantial increase in efficiency by minimizing the overhead of retrieving segment, region, and surface index information from the ray tracing data. Several test problems are assessed: (1) Babcock & Wilcox 1810 Core I, (2) Dimple S01A-Sq, (3) VERA Progression Problem 5a, and (4) VERA Problem 2a. The Jacobi iteration exhibits better stability than Gauss-Seidel, allowing for converged solutions to be obtained over a much wider range of iteration control parameters. Additionally, the MOC solve time with the Jacobi approach is roughly 2.0-2.5× faster per sweep. While the performance and stability of

  8. 15 CFR Appendix F to Subpart M of... - Davidson Seamount Management Zone

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false Davidson Seamount Management Zone F Appendix F to Subpart M of Part 922 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE OCEAN AND...

  9. Viscous warm inflation: Hamilton-Jacobi formalism

    NASA Astrophysics Data System (ADS)

    Akhtari, L.; Mohammadi, A.; Sayar, K.; Saaidi, Kh.

    2017-04-01

    Using Hamilton-Jacobi formalism, the scenario of warm inflation with viscous pressure is considered. The formalism gives a way of computing the slow-rolling parameter without extra approximation, and it is well-known as a powerful method in cold inflation. The model is studied in detail for three different cases of the dissipation and bulk viscous pressure coefficients. In the first case where both coefficients are taken as constant, it is shown that the case could not portray warm inflationary scenario compatible with observational data even it is possible to restrict the model parameters. For other cases, the results shows that the model could properly predicts the perturbation parameters in which they stay in perfect agreement with Planck data. As a further argument, r -ns and αs -ns are drown that show the acquired result could stand in acceptable area expressing a compatibility with observational data.

  10. The role of certification in the buyer/planner position: a case study at Harley-Davidson Motor Company.

    PubMed

    Orange, V J; Robinson, D E

    1999-02-01

    The use of buyer/planners may becoming more popular. If they are, the reason is probably that many companies are integrating materiel management skill sets as a way of increasing the effectiveness of their supply chains. Harley-Davidson recently created a supply management function composed of buyer/planners. This article describes the method it used to achieve the transition, the training plan it implemented to support the process, and the role management played in achieving success.

  11. New infinite families of exact sums of squares formulas, Jacobi elliptic functions, and Ramanujan's tau function.

    PubMed

    Milne, S C

    1996-12-24

    In this paper, we give two infinite families of explicit exact formulas that generalize Jacobi's (1829) 4 and 8 squares identities to 4n(2) or 4n(n + 1) squares, respectively, without using cusp forms. Our 24 squares identity leads to a different formula for Ramanujan's tau function tau(n), when n is odd. These results arise in the setting of Jacobi elliptic functions, Jacobi continued fractions, Hankel or Turánian determinants, Fourier series, Lambert series, inclusion/exclusion, Laplace expansion formula for determinants, and Schur functions. We have also obtained many additional infinite families of identities in this same setting that are analogous to the eta-function identities in appendix I of Macdonald's work [Macdonald, I. G. (1972) Invent. Math. 15, 91-143]. A special case of our methods yields a proof of the two conjectured [Kac, V. G. and Wakimoto, M. (1994) in Progress in Mathematics, eds. Brylinski, J.-L., Brylinski, R., Guillemin, V. & Kac, V. (Birkhäuser Boston, Boston, MA), Vol. 123, pp. 415-456] identities involving representing a positive integer by sums of 4n(2) or 4n(n + 1) triangular numbers, respectively. Our 16 and 24 squares identities were originally obtained via multiple basic hypergeometric series, Gustafson's C(l) nonterminating (6)phi(5) summation theorem, and Andrews' basic hypergeometric series proof of Jacobi's 4 and 8 squares identities. We have (elsewhere) applied symmetry and Schur function techniques to this original approach to prove the existence of similar infinite families of sums of squares identities for n(2) or n(n + 1) squares, respectively. Our sums of more than 8 squares identities are not the same as the formulas of Mathews (1895), Glaisher (1907), Ramanujan (1916), Mordell (1917, 1919), Hardy (1918, 1920), Kac and Wakimoto, and many others.

  12. An approach to the interpretation of Cole-Davidson and Cole-Cole dielectric functions

    NASA Astrophysics Data System (ADS)

    Iglesias, T. P.; Vilão, G.; Reis, João Carlos R.

    2017-08-01

    Assuming that a dielectric sample can be described by Debye's model at each frequency, a method based on Cole's treatment is proposed for the direct estimation at experimental frequencies of relaxation times and the corresponding static and infinite-frequency permittivities. These quantities and the link between dielectric strength and mean molecular dipole moment at each frequency could be useful to analyze dielectric relaxation processes. The method is applied to samples that follow a Cole-Cole or a Cole-Davidson dielectric function. A physical interpretation of these dielectric functions is proposed. The behavior of relaxation time with frequency can be distinguished between the two dielectric functions. The proposed method can also be applied to samples following a Navriliak-Negami or any other dielectric function. The dielectric relaxation of a nanofluid consisting of graphene nanoparticles dispersed in the oil squalane is reported and discussed within the novel framework.

  13. Numerical Solution of Hamilton-Jacobi Equations in High Dimension

    DTIC Science & Technology

    2012-11-23

    high dimension FA9550-10-1-0029 Maurizio Falcone Dipartimento di Matematica SAPIENZA-Universita di Roma P. Aldo Moro, 2 00185 ROMA AH930...solution of Hamilton-Jacobi equations in high dimension AFOSR contract n. FA9550-10-1-0029 Maurizio Falcone Dipartimento di Matematica SAPIENZA

  14. Multi-indexed Meixner and little q-Jacobi (Laguerre) polynomials

    NASA Astrophysics Data System (ADS)

    Odake, Satoru; Sasaki, Ryu

    2017-04-01

    As the fourth stage of the project multi-indexed orthogonal polynomials, we present the multi-indexed Meixner and little q-Jacobi (Laguerre) polynomials in the framework of ‘discrete quantum mechanics’ with real shifts defined on the semi-infinite lattice in one dimension. They are obtained, in a similar way to the multi-indexed Laguerre and Jacobi polynomials reported earlier, from the quantum mechanical systems corresponding to the original orthogonal polynomials by multiple application of the discrete analogue of the Darboux transformations or the Crum-Krein-Adler deletion of virtual state vectors. The virtual state vectors are the solutions of the matrix Schrödinger equation on all the lattice points having negative energies and infinite norm. This is in good contrast to the (q-)Racah systems defined on a finite lattice, in which the ‘virtual state’ vectors satisfy the matrix Schrödinger equation except for one of the two boundary points.

  15. Matched asymptotic expansion of the Hamilton-Jacobi-Bellman equation for aeroassisted plane-change maneuvers

    NASA Technical Reports Server (NTRS)

    Calise, Anthony J.; Melamed, Nahum

    1993-01-01

    In this paper we develop a general procedure for constructing a matched asymptotic expansion of the Hamilton-Jacobi-Bellman equation based on the method of characteristics. The development is for a class of perturbation problems whose solution exhibits two-time-scale behavior. A regular expansion for problems of this type is inappropriate since it is not uniformly valid over a narrow range of the independent variable. Of particular interest here is the manner in which matching and boundary conditions are enforced when the expansion is carried out to first order. Two cases are distinguished - one where the left boundary condition coincides with or lies to the right of the singular region and one where the left boundary condition lies to the left of the singular region. A simple example is used to illustrate the procedure, and its potential application to aeroassisted plane change is described.

  16. Dow and Mary Davidson residence - A residence in a hot humid climate with major living spaces in rooms without walls

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Holder, L.M. III; Holder, L.M. IV

    Dow Davidson works out of his home while his wife, Mary, home schools their three children. The entire family uses the house full time throughout the year. Dow and Mary Davidson stressed the importance of a home with minimal site disruption while providing for as many human needs as practical. Specific requirements were for harmony with the natural climate and adjacent bird sanctuary. The clients had a strong preference for a pole structural system reflecting buildings they were familiar with in Hawaii. The house was designed as a pole structure utilizing passive solar heating, natural ventilation, night flushing, daylighting, rainwatermore » harvesting, and an outdoor and indoor living area without walled separation from the climate. This type of open indoor/outdoor living is an extension of the Hawaiian experience. Use of the pole structure system provided compatibility between the residence and the neighboring bird habitat. The completed house easily blended with the surrounding vegetation due to the extensive use of natural materials. Exterior walks and drives, made from caliche and mulch (harvested from cedar cut on-site), helped further balance the structure with the terrain and vegetation.« less

  17. Tensor calculus in polar coordinates using Jacobi polynomials

    NASA Astrophysics Data System (ADS)

    Vasil, Geoffrey M.; Burns, Keaton J.; Lecoanet, Daniel; Olver, Sheehan; Brown, Benjamin P.; Oishi, Jeffrey S.

    2016-11-01

    Spectral methods are an efficient way to solve partial differential equations on domains possessing certain symmetries. The utility of a method depends strongly on the choice of spectral basis. In this paper we describe a set of bases built out of Jacobi polynomials, and associated operators for solving scalar, vector, and tensor partial differential equations in polar coordinates on a unit disk. By construction, the bases satisfy regularity conditions at r = 0 for any tensorial field. The coordinate singularity in a disk is a prototypical case for many coordinate singularities. The work presented here extends to other geometries. The operators represent covariant derivatives, multiplication by azimuthally symmetric functions, and the tensorial relationship between fields. These arise naturally from relations between classical orthogonal polynomials, and form a Heisenberg algebra. Other past work uses more specific polynomial bases for solving equations in polar coordinates. The main innovation in this paper is to use a larger set of possible bases to achieve maximum bandedness of linear operations. We provide a series of applications of the methods, illustrating their ease-of-use and accuracy.

  18. Discontinuous solutions of Hamilton-Jacobi equations on networks

    NASA Astrophysics Data System (ADS)

    Graber, P. J.; Hermosilla, C.; Zidani, H.

    2017-12-01

    This paper studies optimal control problems on networks without controllability assumptions at the junctions. The Value Function associated with the control problem is characterized as the solution to a system of Hamilton-Jacobi equations with appropriate junction conditions. The novel feature of the result lies in that the controllability conditions are not needed and the characterization remains valid even when the Value Function is not continuous.

  19. A new Jacobi spectral collocation method for solving 1+1 fractional Schrödinger equations and fractional coupled Schrödinger systems

    NASA Astrophysics Data System (ADS)

    Bhrawy, A. H.; Doha, E. H.; Ezz-Eldien, S. S.; Van Gorder, Robert A.

    2014-12-01

    The Jacobi spectral collocation method (JSCM) is constructed and used in combination with the operational matrix of fractional derivatives (described in the Caputo sense) for the numerical solution of the time-fractional Schrödinger equation (T-FSE) and the space-fractional Schrödinger equation (S-FSE). The main characteristic behind this approach is that it reduces such problems to those of solving a system of algebraic equations, which greatly simplifies the solution process. In addition, the presented approach is also applied to solve the time-fractional coupled Schrödinger system (T-FCSS). In order to demonstrate the validity and accuracy of the numerical scheme proposed, several numerical examples with their approximate solutions are presented with comparisons between our numerical results and those obtained by other methods.

  20. High-Order Central WENO Schemes for Multi-Dimensional Hamilton-Jacobi Equations

    NASA Technical Reports Server (NTRS)

    Bryson, Steve; Levy, Doron; Biegel, Bryan (Technical Monitor)

    2002-01-01

    We present new third- and fifth-order Godunov-type central schemes for approximating solutions of the Hamilton-Jacobi (HJ) equation in an arbitrary number of space dimensions. These are the first central schemes for approximating solutions of the HJ equations with an order of accuracy that is greater than two. In two space dimensions we present two versions for the third-order scheme: one scheme that is based on a genuinely two-dimensional Central WENO reconstruction, and another scheme that is based on a simpler dimension-by-dimension reconstruction. The simpler dimension-by-dimension variant is then extended to a multi-dimensional fifth-order scheme. Our numerical examples in one, two and three space dimensions verify the expected order of accuracy of the schemes.

  1. Central Schemes for Multi-Dimensional Hamilton-Jacobi Equations

    NASA Technical Reports Server (NTRS)

    Bryson, Steve; Levy, Doron; Biegel, Bryan (Technical Monitor)

    2002-01-01

    We present new, efficient central schemes for multi-dimensional Hamilton-Jacobi equations. These non-oscillatory, non-staggered schemes are first- and second-order accurate and are designed to scale well with an increasing dimension. Efficiency is obtained by carefully choosing the location of the evolution points and by using a one-dimensional projection step. First-and second-order accuracy is verified for a variety of multi-dimensional, convex and non-convex problems.

  2. Hamilton-Jacobi formalism for Podolsky's electromagnetic theory on the null-plane

    NASA Astrophysics Data System (ADS)

    Bertin, M. C.; Pimentel, B. M.; Valcárcel, C. E.; Zambrano, G. E. R.

    2017-08-01

    We develop the Hamilton-Jacobi formalism for Podolsky's electromagnetic theory on the null-plane. The main goal is to build the complete set of Hamiltonian generators of the system as well as to study the canonical and gauge transformations of the theory.

  3. Obituary: John P. Davidson (1924-2010)

    NASA Astrophysics Data System (ADS)

    Twarog, Bruce; Anthony-Twarog, Barbara

    2011-12-01

    Nuclear physicist and astrophysicist John P. Davidson died at his home on January 10, 2010. He was born on July 22, 1924 in Los Angeles, California. Jack followed his high school interests in rocketry and physical science to the University of California, Berkeley, where he earned a Bachelor of Science degree in physics in June 1948 after serving a stint from 1943 to 1946 in the Army Signal Corps in the European Theater of Operations. Following the war and graduation, Jack embarked on a graduate career in nuclear physics at Washington University, St. Louis. While there, he also initiated what became a life-long partnership with Mary Reiser dedicated to issues of social justice by co-founding an organization to lobby for university admission of African-American students, a policy change opposed by physicist and Chancellor, Arthur Holly Compton. Mary and Jack married in 1949. Jack Davidson's academic career began shortly after completion of his PhD in 1952 under Eugene Feenberg. He taught in Brazil and in Norway before becoming an assistant professor at Rensselaer Polytechnic Institute in 1957. He stayed at RPI until 1966, at which time he joined the faculty of the University of Kansas where he served faculty and students until his retirement in 1996. His teaching, research and administrative career at KU was distinguished by a growing commitment to the astronomy and astrophysics program. Not only did he foster its growth during his tenure as department chair (1977-1989), he directed a residential summer science program in astronomy for high school students at KU for nearly 10 years in the 1970's. He combined his background in nuclear physics and his fascination with astrophysics into a research program to study elemental abundance anomalies in stellar spectra, authoring with Don Bord several pioneering applications of wavelength coincidence statistics to the ultraviolet spectra of peculiar A stars. At KU, Jack assumed leadership roles in the local chapter of Phi Beta

  4. Reconstruction of color biomedical images by means of quaternion generic Jacobi-Fourier moments in the framework of polar pixels

    PubMed Central

    Camacho-Bello, César; Padilla-Vivanco, Alfonso; Toxqui-Quitl, Carina; Báez-Rojas, José Javier

    2016-01-01

    Abstract. A detailed analysis of the quaternion generic Jacobi-Fourier moments (QGJFMs) for color image description is presented. In order to reach numerical stability, a recursive approach is used during the computation of the generic Jacobi radial polynomials. Moreover, a search criterion is performed to establish the best values for the parameters α and β of the radial Jacobi polynomial families. Additionally, a polar pixel approach is taken into account to increase the numerical accuracy in the calculation of the QGJFMs. To prove the mathematical theory, some color images from optical microscopy and human retina are used. Experiments and results about color image reconstruction are presented. PMID:27014716

  5. General relativity in two dimensions: A Hamilton-Jacobi analysis

    NASA Astrophysics Data System (ADS)

    Bertin, M. C.; Pimentel, B. M.; Pompeia, P. J.

    2010-11-01

    We analyzed the constraint structure of the Einstein-Hilbert first-order action in two dimensions using the Hamilton-Jacobi approach. We were able to find a set of involutive, as well as a set of non-involutive constraints. Using generalized brackets we showed how to assure integrability of the theory, to eliminate the set of non-involutive constraints and how to build the field equations.

  6. State of Utopia v. Jamie Davidson. 2002-2003 Oklahoma High School Mock Trial Program.

    ERIC Educational Resources Information Center

    Benischek, Sandra; Davis, Courtney; Horton, Johnathan; Longwell, Nicole; Williams, Keri

    In the spring of 2001, illegal drug use had risen by 40% among teens in the town of Springdale, Utopia. School administrators and the Springdale Police Department decided to implement a crackdown on teen drug use in all high schools in Springdale. A high school principal received a tip on a hotline that Jamie Davidson, a senior, had been seen…

  7. On the conservation of the Jacobi integral in the post-Newtonian circular restricted three-body problem

    NASA Astrophysics Data System (ADS)

    Dubeibe, F. L.; Lora-Clavijo, F. D.; González, Guillermo A.

    2017-05-01

    In the present paper, using the first-order approximation of the n-body Lagrangian (derived on the basis of the post-Newtonian gravitational theory of Einstein, Infeld, and Hoffman), we explicitly write down the equations of motion for the planar circular restricted three-body problem in the Solar system. Additionally, with some simplified assumptions, we obtain two formulas for estimating the values of the mass-distance and velocity-speed of light ratios appropriate for a given post-Newtonian approximation. We show that the formulas derived in the present study, lead to good numerical accuracy in the conservation of the Jacobi constant and almost allow for an equivalence between the Lagrangian and Hamiltonian approaches at the same post-Newtonian order. Accordingly, the dynamics of the system is analyzed in terms of the Poincaré sections method and Lyapunov exponents, finding that for specific values of the Jacobi constant the dynamics can be either chaotic or regular. Our results suggest that the chaoticity of the post-Newtonian system is slightly increased in comparison with its Newtonian counterpart.

  8. Larval development of Brachiopod Coptothyris grayi (Davidson, 1852) (Brachiopoda, Rhynchonelliformea).

    PubMed

    Kuzmina, T V; Temereva, E N; Malakhov, V V

    2016-11-01

    The larval development of the Brachiopod Coptothyris grayi (Davidson, 1852) from the Sea of Japan is described for the first time. Ciliated blastula proved to represent the first free-swimming stage. The blastopore is initially formed as a rounded hole stretching later along the anteroposterior axis. The larva is first divided into two lobes (the apical lobe and the trunk); the mantle lobe is formed later as two lateral folds. Two pairs of seta bundles appear in the late stage larvae. The apical larval lobe in brachiopods is supposed to match the pre-oral lobe and anterior part of the trunk with tentacles in phoronids.

  9. Utilization of EREP data in geological evaluation, regional planning, forest management, and water management in North Carolina. [emphasizing Davidson and Durham Counties

    NASA Technical Reports Server (NTRS)

    Welby, C. W. (Principal Investigator)

    1975-01-01

    The author has identified the following significant results. Skylab imagery was evaluated, compiling vegetational and land use information in conjunction with a potential state park site fin along the Eno River in Durham County. Preliminary evaluation indicates that accuracy of identification was at the 90% level. Attempts at distinguishing between rock types in the Piedmont have proved generally unsuccessful, and recognition of linear features seems the best geologic use which the imagery can be put. The study concentrated on the High Rock Lake area of Davidson County. A study evaluating Skylab photographs for land use mapping in urban and rural areas of Piedmont North Carolina shows that S190A and S190B as well as U-2 imagery have almost the same accuracy when the interpretations are assessed with the square grid sampling method, even though the S190B imagery basically has a greater resolution.

  10. Numerical study on the incompressible Euler equations as a Hamiltonian system: Sectional curvature and Jacobi field

    NASA Astrophysics Data System (ADS)

    Ohkitani, K.

    2010-05-01

    We study some of the key quantities arising in the theory of [Arnold "Sur la geometrie differentielle des groupes de Lie de dimension infinie et ses applications a l'hydrodynamique des fluides parfaits," Annales de l'institut Fourier 16, 319 (1966)] of the incompressible Euler equations both in two and three dimensions. The sectional curvatures for the Taylor-Green vortex and the ABC flow initial conditions are calculated exactly in three dimensions. We trace the time evolution of the Jacobi fields by direct numerical simulations and, in particular, see how the sectional curvatures get more and more negative in time. The spatial structure of the Jacobi fields is compared to the vorticity fields by visualizations. The Jacobi fields are found to grow exponentially in time for the flows with negative sectional curvatures. In two dimensions, a family of initial data proposed by Arnold (1966) is considered. The sectional curvature is observed to change its sign quickly even if it starts from a positive value. The Jacobi field is shown to be correlated with the passive scalar gradient in spatial structure. On the basis of Rouchon's physical-space based expression for the sectional curvature (1984), the origin of negative curvature is investigated. It is found that a "potential" αξ appearing in the definition of covariant time derivative plays an important role, in that a rapid growth in its gradient makes a major contribution to the negative curvature.

  11. Hamilton-Jacobi formalism for inflation with non-minimal derivative coupling

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sheikhahmadi, Haidar; Saridakis, Emmanuel N.; Aghamohammadi, Ali

    2016-10-01

    In inflation with nonminimal derivative coupling there is not a conformal transformation to the Einstein frame where calculations are straightforward, and thus in order to extract inflationary observables one needs to perform a detailed and lengthy perturbation investigation. In this work we bypass this problem by performing a Hamilton-Jacobi analysis, namely rewriting the cosmological equations considering the scalar field to be the time variable. We apply the method to two specific models, namely the power-law and the exponential cases, and for each model we calculate various observables such as the tensor-to-scalar ratio, and the spectral index and its running. Wemore » compare them with 2013 and 2015 Planck data, and we show that they are in a very good agreement with observations.« less

  12. New Formulae for the High-Order Derivatives of Some Jacobi Polynomials: An Application to Some High-Order Boundary Value Problems

    PubMed Central

    Abd-Elhameed, W. M.

    2014-01-01

    This paper is concerned with deriving some new formulae expressing explicitly the high-order derivatives of Jacobi polynomials whose parameters difference is one or two of any degree and of any order in terms of their corresponding Jacobi polynomials. The derivatives formulae for Chebyshev polynomials of third and fourth kinds of any degree and of any order in terms of their corresponding Chebyshev polynomials are deduced as special cases. Some new reduction formulae for summing some terminating hypergeometric functions of unit argument are also deduced. As an application, and with the aid of the new introduced derivatives formulae, an algorithm for solving special sixth-order boundary value problems are implemented with the aid of applying Galerkin method. A numerical example is presented hoping to ascertain the validity and the applicability of the proposed algorithms. PMID:25386599

  13. The Connor-Davidson Resilience Scale as a Positive Psychology Measure for People with Spinal Cord Injuries

    ERIC Educational Resources Information Center

    Fujikawa, Mayu; Lee, Eun-Jeong; Chan, Fong; Catalano, Denise; Hunter, Celeste; Bengtson, Kevin; Rahimi, Maryam

    2013-01-01

    The main objective of this study is to evaluate the measurement structure of the Connor-Davidson Resilience Scale (CD-RISC) as a positive psychology measure for people with spinal cord injuries (SCIs) using confirmatory factor analysis. The participants consisted of 274 Canadians with SCI living in the community. The result indicated that the…

  14. Reliability and validity of the korean version of the connor-davidson resilience scale.

    PubMed

    Baek, Hyun-Sook; Lee, Kyoung-Uk; Joo, Eun-Jeong; Lee, Mi-Young; Choi, Kyeong-Sook

    2010-06-01

    The Connor-Davidson Resilience Scale (CD-RISC) measures various aspects of psychological resilience in patients with posttraumatic stress disorder (PTSD) and other psychiatric ailments. This study sought to assess the reliability and validity of the Korean version of the Connor-Davidson Resilience Scale (K-CD-RISC). In total, 576 participants were enrolled (497 females and 79 males), including hospital nurses, university students, and firefighters. Subjects were evaluated using the K-CD-RISC, the Beck Depression Inventory (BDI), the Impact of Event Scale-Revised (IES-R), the Rosenberg Self-Esteem Scale (RSES), and the Perceived Stress Scale (PSS). Test-retest reliability and internal consistency were examined as a measure of reliability, and convergent validity and factor analysis were also performed to evaluate validity. Cronbach's alpha coefficient and test-retest reliability were 0.93 and 0.93, respectively. The total score on the K-CD-RISC was positively correlated with the RSES (r=0.56, p<0.01). Conversely, BDI (r=-0.46, p<0.01), PSS (r=-0.32, p<0.01), and IES-R scores (r=-0.26, p<0.01) were negatively correlated with the K-CD-RISC. The K-CD-RISC showed a five-factor structure that explained 57.2% of the variance. The K-CD-RISC showed good reliability and validity for measurement of resilience among Korean subjects.

  15. Motion of charged particle in Reissner-Nordström spacetime: a Jacobi-metric approach

    NASA Astrophysics Data System (ADS)

    Das, Praloy; Sk, Ripon; Ghosh, Subir

    2017-11-01

    The present work discusses motion of neutral and charged particles in Reissner-Nordström spacetime. The constant energy paths are derived in a variational principle framework using the Jacobi metric which is parameterized by conserved particle energy. Of particular interest is the case of particle charge and Reissner-Nordström black hole charge being of same sign, since this leads to a clash of opposing forces—gravitational (attractive) and Coulomb (repulsive). Our paper aims to complement the recent work of Pugliese et al. (Eur Phys J C 77:206. arXiv:1304.2940, 2017; Phys Rev D 88:024042. arXiv:1303.6250, 2013). The energy dependent Gaussian curvature (induced by the Jacobi metric) plays an important role in classifying the trajectories.

  16. Efficient spectral-Galerkin algorithms for direct solution for second-order differential equations using Jacobi polynomials

    NASA Astrophysics Data System (ADS)

    Doha, E.; Bhrawy, A.

    2006-06-01

    It is well known that spectral methods (tau, Galerkin, collocation) have a condition number of ( is the number of retained modes of polynomial approximations). This paper presents some efficient spectral algorithms, which have a condition number of , based on the Jacobi?Galerkin methods of second-order elliptic equations in one and two space variables. The key to the efficiency of these algorithms is to construct appropriate base functions, which lead to systems with specially structured matrices that can be efficiently inverted. The complexities of the algorithms are a small multiple of operations for a -dimensional domain with unknowns, while the convergence rates of the algorithms are exponentials with smooth solutions.

  17. A finite difference Davidson procedure to sidestep full ab initio hessian calculation: Application to characterization of stationary points and transition state searches

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sharada, Shaama Mallikarjun; Bell, Alexis T., E-mail: mhg@bastille.cchem.berkeley.edu, E-mail: bell@cchem.berkeley.edu; Head-Gordon, Martin, E-mail: mhg@bastille.cchem.berkeley.edu, E-mail: bell@cchem.berkeley.edu

    2014-04-28

    The cost of calculating nuclear hessians, either analytically or by finite difference methods, during the course of quantum chemical analyses can be prohibitive for systems containing hundreds of atoms. In many applications, though, only a few eigenvalues and eigenvectors, and not the full hessian, are required. For instance, the lowest one or two eigenvalues of the full hessian are sufficient to characterize a stationary point as a minimum or a transition state (TS), respectively. We describe here a method that can eliminate the need for hessian calculations for both the characterization of stationary points as well as searches for saddlemore » points. A finite differences implementation of the Davidson method that uses only first derivatives of the energy to calculate the lowest eigenvalues and eigenvectors of the hessian is discussed. This method can be implemented in conjunction with geometry optimization methods such as partitioned-rational function optimization (P-RFO) to characterize stationary points on the potential energy surface. With equal ease, it can be combined with interpolation methods that determine TS guess structures, such as the freezing string method, to generate approximate hessian matrices in lieu of full hessians as input to P-RFO for TS optimization. This approach is shown to achieve significant cost savings relative to exact hessian calculation when applied to both stationary point characterization as well as TS optimization. The basic reason is that the present approach scales one power of system size lower since the rate of convergence is approximately independent of the size of the system. Therefore, the finite-difference Davidson method is a viable alternative to full hessian calculation for stationary point characterization and TS search particularly when analytical hessians are not available or require substantial computational effort.« less

  18. High-Order Semi-Discrete Central-Upwind Schemes for Multi-Dimensional Hamilton-Jacobi Equations

    NASA Technical Reports Server (NTRS)

    Bryson, Steve; Levy, Doron; Biegel, Bran R. (Technical Monitor)

    2002-01-01

    We present high-order semi-discrete central-upwind numerical schemes for approximating solutions of multi-dimensional Hamilton-Jacobi (HJ) equations. This scheme is based on the use of fifth-order central interpolants like those developed in [1], in fluxes presented in [3]. These interpolants use the weighted essentially nonoscillatory (WENO) approach to avoid spurious oscillations near singularities, and become "central-upwind" in the semi-discrete limit. This scheme provides numerical approximations whose error is as much as an order of magnitude smaller than those in previous WENO-based fifth-order methods [2, 1]. Thee results are discussed via examples in one, two and three dimensions. We also pregnant explicit N-dimensional formulas for the fluxes, discuss their monotonicity and tl!e connection between this method and that in [2].

  19. Five million years of compositionally diverse, episodic volcanism: Construction of Davidson Seamount atop an abandoned spreading center

    NASA Astrophysics Data System (ADS)

    Clague, D. A.; Paduan, J. B.; Duncan, R. A.; Huard, J. J.; Davis, A. S.; Castillo, P. R.; Lonsdale, P.; Devogelaere, A.

    2009-12-01

    Davidson Seamount, a volcano located about 80 km off the central California coast, has a volume of ˜320 km3 and consists of a series of parallel ridges serrated with steep cones. Davidson was sampled and its morphology observed during 27 ROV Tiburon dives. During those dives, 286 samples of lava, volcaniclastite, and erratics from the continental margin were collected, with additional samples from one ROV-collected push core and four gravity cores. We report glass compositions for 99 samples and 40Ar-39Ar incremental heating age data for 20 of the samples. The glass analyses are of hawaiite (62%), mugearite (13%), alkalic basalt (9%), and tephrite (8%), with minor transitional basalt (2%), benmoreite (2%), and trachyandesite (2%). The lithologies are irregularly distributed in space and time. The volcano erupted onto crust inferred to be 20 Ma from seafloor magnetic anomalies. Ages of the lavas range from 9.8 to 14.8 Ma. The oldest rocks are from the central ridge, and the youngest are from the flanks and southern end of the edifice. The compositions of the 18 reliably dated volcanic cones vary with age such that the oldest lavas are the most fractionated. The melts lost 65% to nearly 95% of their initial S because of bubble loss during vesiculation, and the shallowest samples have S contents similar to lava erupted subaerially in Hawaii. Despite this similarity in S contents, there is scant other evidence to suggest that Davidson was ever an island. The numerous small cones of disparate chemistry and the long eruptive period suggest episodic growth of the volcano over at least 5 Myr and perhaps as long as 10 Myr if it began to grow when the spreading ridge was abandoned.

  20. High-Order Central WENO Schemes for 1D Hamilton-Jacobi Equations

    NASA Technical Reports Server (NTRS)

    Bryson, Steve; Levy, Doron; Biegel, Bryan A. (Technical Monitor)

    2002-01-01

    In this paper we derive fully-discrete Central WENO (CWENO) schemes for approximating solutions of one dimensional Hamilton-Jacobi (HJ) equations, which combine our previous works. We introduce third and fifth-order accurate schemes, which are the first central schemes for the HJ equations of order higher than two. The core ingredient is the derivation of our schemes is a high-order CWENO reconstructions in space.

  1. The nonconvex multi-dimensional Riemann problem for Hamilton-Jacobi equations

    NASA Technical Reports Server (NTRS)

    Osher, Stanley

    1989-01-01

    Simple inequalities for the Riemann problem for a Hamilton-Jacobi equation in N space dimension when neither the initial data nor the Hamiltonian need be convex (or concave) are presented. The initial data is globally continuous, affine in each orthant, with a possible jump in normal derivative across each coordinate plane, x sub i = 0. The inequalities become equalities wherever a maxmin equals a minmax and thus an exact closed form solution to this problem is then obtained.

  2. Covariant approach of perturbations in Lovelock type brane gravity

    NASA Astrophysics Data System (ADS)

    Bagatella-Flores, Norma; Campuzano, Cuauhtemoc; Cruz, Miguel; Rojas, Efraín

    2016-12-01

    We develop a covariant scheme to describe the dynamics of small perturbations on Lovelock type extended objects propagating in a flat Minkowski spacetime. The higher-dimensional analogue of the Jacobi equation in this theory becomes a wave type equation for a scalar field Φ . Whithin this framework, we analyse the stability of membranes with a de Sitter geometry where we find that the Jacobi equation specializes to a Klein-Gordon (KG) equation for Φ possessing a tachyonic mass. This shows that, to some extent, these types of extended objects share the symmetries of the Dirac-Nambu-Goto (DNG) action which is by no means coincidental because the DNG model is the simplest included in this type of gravity.

  3. Psychometric properties of Connor-Davidson Resilience Scale in a Spanish sample of entrepreneurs.

    PubMed

    Manzano-García, Guadalupe; Ayala Calvo, Juan Carlos

    2013-01-01

    The literature regarding entrepreneurship suggests that the resilience of entrepreneurs may help to explain entrepreneurial success, but there is no resilience measure widely accepted by researchers. This study analyzes the psychometric properties of the Connor and Davidson Resilience Scale (CD-RISC) in a sample of Spanish entrepreneurs. A telephone survey research method was used. The participants were entrepreneurs operating in the business services sector. Interviewers telephoned a total of 900 entrepreneurs of whom 783 produced usable questionnaires. The CD-RISC was used as data collection instrument. We used principal component analysis factor and confirmatory factor analysis to determine the factor structure of the CD-RISC. Confirmatory factor analysis failed to verify the original five-factor structure of the CD-RISC, whereas principal component analysis factor yielded a 3-factor structure of resilience (hardiness, resourcefulness and optimism). In this research, 47.48% of the total variance was accounted for by three factors, and the obtained factor structure was verified through confirmatory factor analysis. The CD-RISC has been shown to be a reliable and valid tool for measuring entrepreneurs' resilience.

  4. On global solutions of the random Hamilton-Jacobi equations and the KPZ problem

    NASA Astrophysics Data System (ADS)

    Bakhtin, Yuri; Khanin, Konstantin

    2018-04-01

    In this paper, we discuss possible qualitative approaches to the problem of KPZ universality. Throughout the paper, our point of view is based on the geometrical and dynamical properties of minimisers and shocks forming interlacing tree-like structures. We believe that the KPZ universality can be explained in terms of statistics of these structures evolving in time. The paper is focussed on the setting of the random Hamilton-Jacobi equations. We formulate several conjectures concerning global solutions and discuss how their properties are connected to the KPZ scalings in dimension 1  +  1. In the case of general viscous Hamilton-Jacobi equations with non-quadratic Hamiltonians, we define generalised directed polymers. We expect that their behaviour is similar to the behaviour of classical directed polymers, and present arguments in favour of this conjecture. We also define a new renormalisation transformation defined in purely geometrical terms and discuss conjectural properties of the corresponding fixed points. Most of our conjectures are widely open, and supported by only partial rigorous results for particular models.

  5. The nonconvex multi-dimensional Riemann problem for Hamilton-Jacobi equations

    NASA Technical Reports Server (NTRS)

    Bardi, Martino; Osher, Stanley

    1991-01-01

    Simple inequalities are presented for the viscosity solution of a Hamilton-Jacobi equation in N space dimensions when neither the initial data nor the Hamiltonian need be convex (or concave). The initial data are uniformly Lipschitz and can be written as the sum of a convex function in a group of variables and a concave function in the remaining variables, therefore including the nonconvex Riemann problem. The inequalities become equalities wherever a 'maxmin' equals a 'minmax', and thus a representation formula for this problem is obtained, generalizing the classical Hopi formulas.

  6. The genus Ivalia Jacoby 1887 (Coleoptera: Chrysomelidae: Galerucinae: Alticini) of the mount Kinabalu, Sabah, Malaysia

    USDA-ARS?s Scientific Manuscript database

    The following new species of Ivalia Jacoby 1887 are described from the mount Kinabalu (Sabah, Malaysia): I. besar, I. biasa, I. fulvomaculata, I. haruka, I. marginata, I. minutissima, I. nigrofasciata, I. pseudostriolata, I. rubrorbiculata, I. striolata. Chabria kinabalensis Bryant 1938 is transferr...

  7. Numerical methods for systems of conservation laws of mixed type using flux splitting

    NASA Technical Reports Server (NTRS)

    Shu, Chi-Wang

    1990-01-01

    The essentially non-oscillatory (ENO) finite difference scheme is applied to systems of conservation laws of mixed hyperbolic-elliptic type. A flux splitting, with the corresponding Jacobi matrices having real and positive/negative eigenvalues, is used. The hyperbolic ENO operator is applied separately. The scheme is numerically tested on the van der Waals equation in fluid dynamics. Convergence was observed with good resolution to weak solutions for various Riemann problems, which are then numerically checked to be admissible as the viscosity-capillarity limits. The interesting phenomena of the shrinking of elliptic regions if they are present in the initial conditions were also observed.

  8. Density-matrix-based algorithm for solving eigenvalue problems

    NASA Astrophysics Data System (ADS)

    Polizzi, Eric

    2009-03-01

    A fast and stable numerical algorithm for solving the symmetric eigenvalue problem is presented. The technique deviates fundamentally from the traditional Krylov subspace iteration based techniques (Arnoldi and Lanczos algorithms) or other Davidson-Jacobi techniques and takes its inspiration from the contour integration and density-matrix representation in quantum mechanics. It will be shown that this algorithm—named FEAST—exhibits high efficiency, robustness, accuracy, and scalability on parallel architectures. Examples from electronic structure calculations of carbon nanotubes are presented, and numerical performances and capabilities are discussed.

  9. The right-hand side of the Jacobi identity: to be naught or not to be ?

    NASA Astrophysics Data System (ADS)

    Kiselev, Arthemy V.

    2016-01-01

    The geometric approach to iterated variations of local functionals -e.g., of the (master-)action functional - resulted in an extension of the deformation quantisation technique to the set-up of Poisson models of field theory. It also allowed of a rigorous proof for the main inter-relations between the Batalin-Vilkovisky (BV) Laplacian Δ and variational Schouten bracket [,]. The ad hoc use of these relations had been a known analytic difficulty in the BV- formalism for quantisation of gauge systems; now achieved, the proof does actually not require the assumption of graded-commutativity. Explained in our previous work, geometry's self- regularisation is rendered by Gel'fand's calculus of singular linear integral operators supported on the diagonal. We now illustrate that analytic technique by inspecting the validity mechanism for the graded Jacobi identity which the variational Schouten bracket does satisfy (whence Δ2 = 0, i.e., the BV-Laplacian is a differential acting in the algebra of local functionals). By using one tuple of three variational multi-vectors twice, we contrast the new logic of iterated variations - when the right-hand side of Jacobi's identity vanishes altogether - with the old method: interlacing its steps and stops, it could produce some non-zero representative of the trivial class in the top- degree horizontal cohomology. But we then show at once by an elementary counterexample why, in the frames of the old approach that did not rely on Gel'fand's calculus, the BV-Laplacian failed to be a graded derivation of the variational Schouten bracket.

  10. Escape rates over potential barriers: variational principles and the Hamilton-Jacobi equation

    NASA Astrophysics Data System (ADS)

    Cortés, Emilio; Espinosa, Francisco

    We describe a rigorous formalism to study some extrema statistics problems, like maximum probability events or escape rate processes, by taking into account that the Hamilton-Jacobi equation completes, in a natural way, the required set of boundary conditions of the Euler-Lagrange equation, for this kind of variational problem. We apply this approach to a one-dimensional stochastic process, driven by colored noise, for a double-parabola potential, where we have one stable and one unstable steady states.

  11. Effects of septic-tank effluent on ground-water quality in northern Williamson County and southern Davidson County, Tennessee

    USGS Publications Warehouse

    Hanchar, D.W.

    1991-01-01

    An investigation of the potential contamination of ground water from septic tank systems blasted in bedrock in Williamson and Davidson Counties, Tennessee, was conducted during 1988-89. Water samples were collected from domestic and observation wells, springs, and surface-water sites in a residential subdivision in the northern part of Williamson County near Nashville. The subdivision has a high density of septic-tank field lines installed into blasted bedrock Water samples also were collected from a well located in an area of Davidson County where field lines were installed in 5 feet of soil. Samples were analyzed for major inorganic constituents, nutrients, total organic carbon, optical brighteners, and bacteria. Although results of analyses of water samples from wells indicate no effect of septic-tank effluent on ground-water quality at these sites, water from two springs located downgradient from the subdivision had slightly larger concentrations of nitrite plus nitrate (2.2 and 2.7 milligrams per liter N), and much larger concentrations of fecal coliform and fecal streptococci bacteria (2,000 to 3,200 and 700 to 900 colonies per 100 milliliters of sample, respectively), than other wells and springs sampled during 1988. Water from one of these springs contained optical brighteners, which indicates that septic-tank effluent is affecting ground-water quality.

  12. Perturbations of Jacobi polynomials and piecewise hypergeometric orthogonal systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Neretin, Yu A

    2006-12-31

    A family of non-complete orthogonal systems of functions on the ray [0,{infinity}] depending on three real parameters {alpha}, {beta}, {theta} is constructed. The elements of this system are piecewise hypergeometric functions with singularity at x=1. For {theta}=0 these functions vanish on [1,{infinity}) and the system is reduced to the Jacobi polynomials P{sub n}{sup {alpha}}{sup ,{beta}} on the interval [0,1]. In the general case the functions constructed can be regarded as an interpretation of the expressions P{sub n+{theta}}{sup {alpha}}{sup ,{beta}}. They are eigenfunctions of an exotic Sturm-Liouville boundary-value problem for the hypergeometric differential operator. The spectral measure for this problem ismore » found.« less

  13. A multigrid method for steady Euler equations on unstructured adaptive grids

    NASA Technical Reports Server (NTRS)

    Riemslagh, Kris; Dick, Erik

    1993-01-01

    A flux-difference splitting type algorithm is formulated for the steady Euler equations on unstructured grids. The polynomial flux-difference splitting technique is used. A vertex-centered finite volume method is employed on a triangular mesh. The multigrid method is in defect-correction form. A relaxation procedure with a first order accurate inner iteration and a second-order correction performed only on the finest grid, is used. A multi-stage Jacobi relaxation method is employed as a smoother. Since the grid is unstructured a Jacobi type is chosen. The multi-staging is necessary to provide sufficient smoothing properties. The domain is discretized using a Delaunay triangular mesh generator. Three grids with more or less uniform distribution of nodes but with different resolution are generated by successive refinement of the coarsest grid. Nodes of coarser grids appear in the finer grids. The multigrid method is started on these grids. As soon as the residual drops below a threshold value, an adaptive refinement is started. The solution on the adaptively refined grid is accelerated by a multigrid procedure. The coarser multigrid grids are generated by successive coarsening through point removement. The adaption cycle is repeated a few times. Results are given for the transonic flow over a NACA-0012 airfoil.

  14. On the Geometry of the Hamilton-Jacobi Equation and Generating Functions

    NASA Astrophysics Data System (ADS)

    Ferraro, Sebastián; de León, Manuel; Marrero, Juan Carlos; Martín de Diego, David; Vaquero, Miguel

    2017-10-01

    In this paper we develop a geometric version of the Hamilton-Jacobi equation in the Poisson setting. Specifically, we "geometrize" what is usually called a complete solution of the Hamilton-Jacobi equation. We use some well-known results about symplectic groupoids, in particular cotangent groupoids, as a keystone for the construction of our framework. Our methodology follows the ambitious program proposed by Weinstein (In Mechanics day (Waterloo, ON, 1992), volume 7 of fields institute communications, American Mathematical Society, Providence, 1996) in order to develop geometric formulations of the dynamical behavior of Lagrangian and Hamiltonian systems on Lie algebroids and Lie groupoids. This procedure allows us to take symmetries into account, and, as a by-product, we recover results from Channell and Scovel (Phys D 50(1):80-88, 1991), Ge (Indiana Univ. Math. J. 39(3):859-876, 1990), Ge and Marsden (Phys Lett A 133(3):134-139, 1988), but even in these situations our approach is new. A theory of generating functions for the Poisson structures considered here is also developed following the same pattern, solving a longstanding problem of the area: how to obtain a generating function for the identity transformation and the nearby Poisson automorphisms of Poisson manifolds. A direct application of our results gives the construction of a family of Poisson integrators, that is, integrators that conserve the underlying Poisson geometry. These integrators are implemented in the paper in benchmark problems. Some conclusions, current and future directions of research are shown at the end of the paper.

  15. Hamilton-Jacobi-Bellman equations and approximate dynamic programming on time scales.

    PubMed

    Seiffertt, John; Sanyal, Suman; Wunsch, Donald C

    2008-08-01

    The time scales calculus is a key emerging area of mathematics due to its potential use in a wide variety of multidisciplinary applications. We extend this calculus to approximate dynamic programming (ADP). The core backward induction algorithm of dynamic programming is extended from its traditional discrete case to all isolated time scales. Hamilton-Jacobi-Bellman equations, the solution of which is the fundamental problem in the field of dynamic programming, are motivated and proven on time scales. By drawing together the calculus of time scales and the applied area of stochastic control via ADP, we have connected two major fields of research.

  16. Notes on the occurrence of Oligonychus milleri (McGregor) and oligonychus ununguis (Jacobi) (Acari: Tetranychidae) in Brazil

    USDA-ARS?s Scientific Manuscript database

    We verified infestation of Oligonychus milleri (McGregor) on plantations of Pinus caribaea (Pinaceae) and of Oligonychus ununguis (Jacobi) on plantations of Eucalyptus urophylla x Eucalyptus grandis (Myrtaceae) in State of Rondônia, Northern region of Brazil. This represents the first record of O. m...

  17. Science, suffrage, and experimentation: Mary Putnam Jacobi and the controversy over vivisection in late nineteenth-century America.

    PubMed

    Bittel, Carla Jean

    2005-01-01

    This article examines the medical activism of the New York physician Mary Putnam Jacobi (1842-1906), to illustrate the problems of gender and science at the center of the vivisection debate in late nineteenth-century America. In the post-Civil War era, individuals both inside and outside the medical community considered vivisection to be a controversial practice. Physicians divided over the value of live animal experimentation, while reformers and activists campaigned against it. Jacobi stepped into the center of the controversy and tried to use her public defense of experimentation to the advantage of women in the medical profession. Her advocacy of vivisection was part of her broader effort to reform medical education, especially at women's institutions. It was also a political strategy aimed at associating women with scientific practices to advance a women's rights agenda. Her work demonstrates how debates over women in medicine and science in medicine, suffrage, and experimentation overlapped at a critical moment of historical transition.

  18. A second order discontinuous Galerkin fast sweeping method for Eikonal equations

    NASA Astrophysics Data System (ADS)

    Li, Fengyan; Shu, Chi-Wang; Zhang, Yong-Tao; Zhao, Hongkai

    2008-09-01

    In this paper, we construct a second order fast sweeping method with a discontinuous Galerkin (DG) local solver for computing viscosity solutions of a class of static Hamilton-Jacobi equations, namely the Eikonal equations. Our piecewise linear DG local solver is built on a DG method developed recently [Y. Cheng, C.-W. Shu, A discontinuous Galerkin finite element method for directly solving the Hamilton-Jacobi equations, Journal of Computational Physics 223 (2007) 398-415] for the time-dependent Hamilton-Jacobi equations. The causality property of Eikonal equations is incorporated into the design of this solver. The resulting local nonlinear system in the Gauss-Seidel iterations is a simple quadratic system and can be solved explicitly. The compactness of the DG method and the fast sweeping strategy lead to fast convergence of the new scheme for Eikonal equations. Extensive numerical examples verify efficiency, convergence and second order accuracy of the proposed method.

  19. Stabilization of a gravel channel by large streamside obstructions and bedrock bends, Jacoby Creek, northwestern California

    Treesearch

    Thomas E. Lisle

    1996-01-01

    Abstract - Jacoby Creek (bed width =12 m; bankfull discharge = 32.6 m 3 /s) contains stationary gravel bars that have forms and positions controlled by numerous large streamside obstructions (bedrock outcrops, large woody debris, and rooted bank projections) and bedrock bends. Bank-projection width and bar volume measured in 104 channel segments 1 bed-width long are...

  20. The luminosities of cool supergiants in the Magellanic Clouds, and the Humphreys-Davidson limit revisited

    NASA Astrophysics Data System (ADS)

    Davies, Ben; Crowther, Paul A.; Beasor, Emma R.

    2018-05-01

    The empirical upper luminosity boundary Lmax of cool supergiants, often referred to as the Humphreys-Davidson limit, is thought to encode information on the general mass-loss behaviour of massive stars. Further, it delineates the boundary at which single stars will end their lives stripped of their hydrogen-rich envelope, which in turn is a key factor in the relative rates of Type-II to Type-Ibc supernovae from single star channels. In this paper we have revisited the issue of Lmax by studying the luminosity distributions of cool supergiants (SGs) in the Large and Small Magellanic Clouds (LMC/SMC). We assemble samples of cool SGs in each galaxy which are highly-complete above log L/L⊙=5.0, and determine their spectral energy distributions from the optical to the mid-infrared using modern multi-wavelength survey data. We show that in both cases Lmax appears to be lower than previously quoted, and is in the region of log L/L⊙=5.5. There is no evidence for Lmax being higher in the SMC than in the LMC, as would be expected if metallicity-dependent winds were the dominant factor in the stripping of stellar envelopes. We also show that Lmax aligns with the lowest luminosity of single nitrogen-rich Wolf-Rayet stars, indicating of a change in evolutionary sequence for stars above a critical mass. From population synthesis analysis we show that the Geneva evolutionary models greatly over-predict the numbers of cool SGs in the SMC. We also argue that the trend of earlier average spectral types of cool SGs in lower metallicity environments represents a genuine shift to hotter temperatures. Finally, we use our new bolometric luminosity measurements to provide updated bolometric corrections for cool supergiants.

  1. Periodic solutions of the Hamilton-Jacobi equation with a periodic non-homogeneous term and Aubry-Mather theory

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sobolevskii, A N

    It is proved that the one-dimensional Hamilton-Jacobi equation with a periodic non-homogeneous term admits a family of generalized solutions, each of which can be represented as the sum of a linear and a periodic function; a condition for the uniqueness of such a solution is given in terms of Aubry-Mather theory.

  2. Numerical Schemes for the Hamilton-Jacobi and Level Set Equations on Triangulated Domains

    NASA Technical Reports Server (NTRS)

    Barth, Timothy J.; Sethian, James A.

    2006-01-01

    Borrowing from techniques developed for conservation law equations, we have developed both monotone and higher order accurate numerical schemes which discretize the Hamilton-Jacobi and level set equations on triangulated domains. The use of unstructured meshes containing triangles (2D) and tetrahedra (3D) easily accommodates mesh adaptation to resolve disparate level set feature scales with a minimal number of solution unknowns. The minisymposium talk will discuss these algorithmic developments and present sample calculations using our adaptive triangulation algorithm applied to various moving interface problems such as etching, deposition, and curvature flow.

  3. Optimization of the launcher ascent trajectory leading to the global optimum without any initialization: the breakthrough of the Hamilton-Jacobi-Bellman approach

    NASA Astrophysics Data System (ADS)

    Bourgeois, E.; Bokanowski, O.; Zidani, H.; Désilles, A.

    2018-06-01

    The resolution of the launcher ascent trajectory problem by the so-called Hamilton-Jacobi-Bellman (HJB) approach, relying on the Dynamic Programming Principle, has been investigated. The method gives a global optimum and does not need any initialization procedure. Despite these advantages, this approach is seldom used because of the dicculties of computing the solution of the HJB equation for high dimension problems. The present study shows that an eccient resolution is found. An illustration of the method is proposed on a heavy class launcher, for a typical GEO (Geostationary Earth Orbit) mission. This study has been performed in the frame of the Centre National d'Etudes Spatiales (CNES) Launchers Research & Technology Program.

  4. Derivation of the Schrodinger Equation from the Hamilton-Jacobi Equation in Feynman's Path Integral Formulation of Quantum Mechanics

    ERIC Educational Resources Information Center

    Field, J. H.

    2011-01-01

    It is shown how the time-dependent Schrodinger equation may be simply derived from the dynamical postulate of Feynman's path integral formulation of quantum mechanics and the Hamilton-Jacobi equation of classical mechanics. Schrodinger's own published derivations of quantum wave equations, the first of which was also based on the Hamilton-Jacobi…

  5. Restoration of four-dimensional diffeomorphism covariance in canonical general relativity: An intrinsic Hamilton-Jacobi approach

    NASA Astrophysics Data System (ADS)

    Salisbury, Donald; Renn, Jürgen; Sundermeyer, Kurt

    2016-02-01

    Classical background independence is reflected in Lagrangian general relativity through covariance under the full diffeomorphism group. We show how this independence can be maintained in a Hamilton-Jacobi approach that does not accord special privilege to any geometric structure. Intrinsic space-time curvature-based coordinates grant equal status to all geometric backgrounds. They play an essential role as a starting point for inequivalent semiclassical quantizations. The scheme calls into question Wheeler’s geometrodynamical approach and the associated Wheeler-DeWitt equation in which 3-metrics are featured geometrical objects. The formalism deals with variables that are manifestly invariant under the full diffeomorphism group. Yet, perhaps paradoxically, the liberty in selecting intrinsic coordinates is precisely as broad as is the original diffeomorphism freedom. We show how various ideas from the past five decades concerning the true degrees of freedom of general relativity can be interpreted in light of this new constrained Hamiltonian description. In particular, we show how the Kuchař multi-fingered time approach can be understood as a means of introducing full four-dimensional diffeomorphism invariants. Every choice of new phase space variables yields new Einstein-Hamilton-Jacobi constraining relations, and corresponding intrinsic Schrödinger equations. We show how to implement this freedom by canonical transformation of the intrinsic Hamiltonian. We also reinterpret and rectify significant work by Dittrich on the construction of “Dirac observables.”

  6. The Psychometric Evaluation of the Connor-Davidson Resilience Scale Using a Chinese Military Sample

    PubMed Central

    Xie, Yuanjun; Peng, Li; Zuo, Xin; Li, Min

    2016-01-01

    This study examined the psychometric properties of the Connor-Davidson Resilience Scale (CD-RISC) with a Chinese military population with the aim of finding a suitable instrument to quantify resilience in Chinese military service members. The confirmatory factor analysis results did not support the factorial structure of the original or the Chinese community version of the CD-RISC, but the exploratory factor analysis results revealed a three-factor model (composed of Competency, Toughness, and Adaptability) that seemed to fit. Moreover, the repeat confirmatory factory analysis replicated the three-factor model. Additionally, the CD-RISC with a Chinese military sample exhibited appropriate psychometric properties, including internal consistency, test-retest reliability, and structural and concurrent validity. The revised CD-RISC with a Chinese military sample provides insight into the resilience measurement framework and could be a reliable and valid measurement for evaluating resilience in a Chinese military population. PMID:26859484

  7. Quadratically Convergent Method for Simultaneously Approaching the Roots of Polynomial Solutions of a Class of Differential Equations

    NASA Astrophysics Data System (ADS)

    Recchioni, Maria Cristina

    2001-12-01

    This paper investigates the application of the method introduced by L. Pasquini (1989) for simultaneously approaching the zeros of polynomial solutions to a class of second-order linear homogeneous ordinary differential equations with polynomial coefficients to a particular case in which these polynomial solutions have zeros symmetrically arranged with respect to the origin. The method is based on a family of nonlinear equations which is associated with a given class of differential equations. The roots of the nonlinear equations are related to the roots of the polynomial solutions of differential equations considered. Newton's method is applied to find the roots of these nonlinear equations. In (Pasquini, 1994) the nonsingularity of the roots of these nonlinear equations is studied. In this paper, following the lines in (Pasquini, 1994), the nonsingularity of the roots of these nonlinear equations is studied. More favourable results than the ones in (Pasquini, 1994) are proven in the particular case of polynomial solutions with symmetrical zeros. The method is applied to approximate the roots of Hermite-Sobolev type polynomials and Freud polynomials. A lower bound for the smallest positive root of Hermite-Sobolev type polynomials is given via the nonlinear equation. The quadratic convergence of the method is proven. A comparison with a classical method that uses the Jacobi matrices is carried out. We show that the algorithm derived by the proposed method is sometimes preferable to the classical QR type algorithms for computing the eigenvalues of the Jacobi matrices even if these matrices are real and symmetric.

  8. Classification of Hamilton-Jacobi separation in orthogonal coordinates with diagonal curvature

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rajaratnam, Krishan, E-mail: k2rajara@uwaterloo.ca; McLenaghan, Raymond G., E-mail: rgmclenaghan@uwaterloo.ca

    2014-08-15

    We find all orthogonal metrics where the geodesic Hamilton-Jacobi equation separates and the Riemann curvature tensor satisfies a certain equation (called the diagonal curvature condition). All orthogonal metrics of constant curvature satisfy the diagonal curvature condition. The metrics we find either correspond to a Benenti system or are warped product metrics where the induced metric on the base manifold corresponds to a Benenti system. Furthermore, we show that most metrics we find are characterized by concircular tensors; these metrics, called Kalnins-Eisenhart-Miller metrics, have an intrinsic characterization which can be used to obtain them on a given space. In conjunction withmore » other results, we show that the metrics we found constitute all separable metrics for Riemannian spaces of constant curvature and de Sitter space.« less

  9. Algorithm for Overcoming the Curse of Dimensionality for Certain Non-convex Hamilton-Jacobi Equations, Projections and Differential Games

    DTIC Science & Technology

    2016-05-01

    Algorithm for Overcoming the Curse of Dimensionality for Certain Non-convex Hamilton-Jacobi Equations, Projections and Differential Games Yat Tin...subproblems. Our approach is expected to have wide applications in continuous dynamic games , control theory problems, and elsewhere. Mathematics...differential dynamic games , control theory problems, and dynamical systems coming from the physical world, e.g. [11]. An important application is to

  10. Notes on the Occurrence of Oligonychus milleri (McGregor) and Oligonychus ununguis (Jacobi) (Acari: Tetranychidae) in Brazil.

    PubMed

    Castro, E B; Zanardi, O C; Garlet, J; Ochoa, R; Feres, R J F

    2018-06-01

    We verified infestation of Oligonychus milleri (McGregor) on plantations of Pinus caribaea (Pinaceae) and of Oligonychus ununguis (Jacobi) on plantations of Eucalyptus urophylla x Eucalyptus grandis (Myrtaceae) in State of Rondônia, Northern region of Brazil. This represents the first record of O. milleri in Brazil. Oligonychus ununguis was recorded previously, on cypress. The damage caused by these two spider mites in the plantations is described herein.

  11. Separation of variables in the special diagonal Hamilton-Jacobi equation: Application to the dynamical problem of a particle constrained on a moving surface

    NASA Technical Reports Server (NTRS)

    Blanchard, D. L.; Chan, F. K.

    1973-01-01

    For a time-dependent, n-dimensional, special diagonal Hamilton-Jacobi equation a necessary and sufficient condition for the separation of variables to yield a complete integral of the form was established by specifying the admissible forms in terms of arbitrary functions. A complete integral was then expressed in terms of these arbitrary functions and also the n irreducible constants. As an application of the results obtained for the two-dimensional Hamilton-Jacobi equation, analysis was made for a comparatively wide class of dynamical problems involving a particle moving in Euclidean three-dimensional space under the action of external forces but constrained on a moving surface. All the possible cases in which this equation had a complete integral of the form were obtained and these are tubulated for reference.

  12. F-Expansion Method and New Exact Solutions of the Schrödinger-KdV Equation

    PubMed Central

    Filiz, Ali; Ekici, Mehmet; Sonmezoglu, Abdullah

    2014-01-01

    F-expansion method is proposed to seek exact solutions of nonlinear evolution equations. With the aid of symbolic computation, we choose the Schrödinger-KdV equation with a source to illustrate the validity and advantages of the proposed method. A number of Jacobi-elliptic function solutions are obtained including the Weierstrass-elliptic function solutions. When the modulus m of Jacobi-elliptic function approaches to 1 and 0, soliton-like solutions and trigonometric-function solutions are also obtained, respectively. The proposed method is a straightforward, short, promising, and powerful method for the nonlinear evolution equations in mathematical physics. PMID:24672327

  13. F-expansion method and new exact solutions of the Schrödinger-KdV equation.

    PubMed

    Filiz, Ali; Ekici, Mehmet; Sonmezoglu, Abdullah

    2014-01-01

    F-expansion method is proposed to seek exact solutions of nonlinear evolution equations. With the aid of symbolic computation, we choose the Schrödinger-KdV equation with a source to illustrate the validity and advantages of the proposed method. A number of Jacobi-elliptic function solutions are obtained including the Weierstrass-elliptic function solutions. When the modulus m of Jacobi-elliptic function approaches to 1 and 0, soliton-like solutions and trigonometric-function solutions are also obtained, respectively. The proposed method is a straightforward, short, promising, and powerful method for the nonlinear evolution equations in mathematical physics.

  14. A Piecewise Deterministic Markov Toy Model for Traffic/Maintenance and Associated Hamilton–Jacobi Integrodifferential Systems on Networks

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Goreac, Dan, E-mail: Dan.Goreac@u-pem.fr; Kobylanski, Magdalena, E-mail: Magdalena.Kobylanski@u-pem.fr; Martinez, Miguel, E-mail: Miguel.Martinez@u-pem.fr

    2016-10-15

    We study optimal control problems in infinite horizon whxen the dynamics belong to a specific class of piecewise deterministic Markov processes constrained to star-shaped networks (corresponding to a toy traffic model). We adapt the results in Soner (SIAM J Control Optim 24(6):1110–1122, 1986) to prove the regularity of the value function and the dynamic programming principle. Extending the networks and Krylov’s “shaking the coefficients” method, we prove that the value function can be seen as the solution to a linearized optimization problem set on a convenient set of probability measures. The approach relies entirely on viscosity arguments. As a by-product,more » the dual formulation guarantees that the value function is the pointwise supremum over regular subsolutions of the associated Hamilton–Jacobi integrodifferential system. This ensures that the value function satisfies Perron’s preconization for the (unique) candidate to viscosity solution.« less

  15. Ballistic Transport for Limit-Periodic Jacobi Matrices with Applications to Quantum Many-Body Problems

    NASA Astrophysics Data System (ADS)

    Fillman, Jake

    2017-03-01

    We study Jacobi matrices that are uniformly approximated by periodic operators. We show that if the rate of approximation is sufficiently rapid, then the associated quantum dynamics are ballistic in a rather strong sense; namely, the (normalized) Heisenberg evolution of the position operator converges strongly to a self-adjoint operator that is injective on the space of absolutely summable sequences. In particular, this means that all transport exponents corresponding to well-localized initial states are equal to one. Our result may be applied to a class of quantum many-body problems. Specifically, we establish a lower bound on the Lieb-Robinson velocity for an isotropic XY spin chain on the integers with limit-periodic couplings.

  16. Dynamical behavior and Jacobi stability analysis of wound strings

    NASA Astrophysics Data System (ADS)

    Lake, Matthew J.; Harko, Tiberiu

    2016-06-01

    We numerically solve the equations of motion (EOM) for two models of circular cosmic string loops with windings in a simply connected internal space. Since the windings cannot be topologically stabilized, stability must be achieved (if at all) dynamically. As toy models for realistic compactifications, we consider windings on a small section of mathbb {R}^2, which is valid as an approximation to any simply connected internal manifold if the winding radius is sufficiently small, and windings on an S^2 of constant radius mathcal {R}. We then use Kosambi-Cartan-Chern (KCC) theory to analyze the Jacobi stability of the string equations and determine bounds on the physical parameters that ensure dynamical stability of the windings. We find that, for the same initial conditions, the curvature and topology of the internal space have nontrivial effects on the microscopic behavior of the string in the higher dimensions, but that the macroscopic behavior is remarkably insensitive to the details of the motion in the compact space. This suggests that higher-dimensional signatures may be extremely difficult to detect in the effective (3+1)-dimensional dynamics of strings compactified on an internal space, even if configurations with nontrivial windings persist over long time periods.

  17. An in-depth psychometric analysis of the Connor-Davidson Resilience Scale: calibration with Rasch-Andrich model.

    PubMed

    Arias González, Víctor B; Crespo Sierra, María Teresa; Arias Martínez, Benito; Martínez-Molina, Agustín; Ponce, Fernando P

    2015-09-23

    The Connor-Davidson Resilience Scale (CD-RISC) is inarguably one of the best-known instruments in the field of resilience assessment. However, the criteria for the psychometric quality of the instrument were based only on classical test theory. The aim of this paper has focused on the calibration of the CD-RISC with a nonclinical sample of 444 adults using the Rasch-Andrich Rating Scale Model, in order to clarify its structure and analyze its psychometric properties at the level of item. Two items showed misfit to the model and were eliminated. The remaining 22 items form basically a unidimensional scale. The CD-RISC has good psychometric properties. The fit of both the items and the persons to the Rasch model was good, and the response categories were functioning properly. Two of the items showed differential item functioning. The CD-RISC has an obvious ceiling effect, which suggests to include more difficult items in future versions of the scale.

  18. Chain mapping approach of Hamiltonian for FMO complex using associated, generalized and exceptional Jacobi polynomials

    NASA Astrophysics Data System (ADS)

    Mahdian, M.; Arjmandi, M. B.; Marahem, F.

    2016-06-01

    The excitation energy transfer (EET) in photosynthesis complex has been widely investigated in recent years. However, one of the main problems is simulation of this complex under realistic condition. In this paper by using the associated, generalized and exceptional Jacobi polynomials, firstly, we introduce the spectral density of Fenna-Matthews-Olson (FMO) complex. Afterward, we obtain a map that transforms the Hamiltonian of FMO complex as an open quantum system to a one-dimensional chain of oscillatory modes with only nearest neighbor interaction in which the system is coupled only to first mode of chain. The frequency and coupling strength of each mode can be analytically obtained from recurrence coefficient of mentioned orthogonal polynomials.

  19. Inverse Jacobi multiplier as a link between conservative systems and Poisson structures

    NASA Astrophysics Data System (ADS)

    García, Isaac A.; Hernández-Bermejo, Benito

    2017-08-01

    Some aspects of the relationship between conservativeness of a dynamical system (namely the preservation of a finite measure) and the existence of a Poisson structure for that system are analyzed. From the local point of view, due to the flow-box theorem we restrict ourselves to neighborhoods of singularities. In this sense, we characterize Poisson structures around the typical zero-Hopf singularity in dimension 3 under the assumption of having a local analytic first integral with non-vanishing first jet by connecting with the classical Poincaré center problem. From the global point of view, we connect the property of being strictly conservative (the invariant measure must be positive) with the existence of a Poisson structure depending on the phase space dimension. Finally, weak conservativeness in dimension two is introduced by the extension of inverse Jacobi multipliers as weak solutions of its defining partial differential equation and some of its applications are developed. Examples including Lotka-Volterra systems, quadratic isochronous centers, and non-smooth oscillators are provided.

  20. Symmetric tops in combined electric fields: Conditional quasisolvability via the quantum Hamilton-Jacobi theory

    NASA Astrophysics Data System (ADS)

    Schatz, Konrad; Friedrich, Bretislav; Becker, Simon; Schmidt, Burkhard

    2018-05-01

    We make use of the quantum Hamilton-Jacobi (QHJ) theory to investigate conditional quasisolvability of the quantum symmetric top subject to combined electric fields (symmetric top pendulum). We derive the conditions of quasisolvability of the time-independent Schrödinger equation as well as the corresponding finite sets of exact analytic solutions. We do so for this prototypical trigonometric system as well as for its anti-isospectral hyperbolic counterpart. An examination of the algebraic and numerical spectra of these two systems reveals mutually closely related patterns. The QHJ approach allows us to retrieve the closed-form solutions for the spherical and planar pendula and the Razavy system that had been obtained in our earlier work via supersymmetric quantum mechanics as well as to find a cornucopia of additional exact analytic solutions.

  1. On mixed derivatives type high dimensional multi-term fractional partial differential equations approximate solutions

    NASA Astrophysics Data System (ADS)

    Talib, Imran; Belgacem, Fethi Bin Muhammad; Asif, Naseer Ahmad; Khalil, Hammad

    2017-01-01

    In this research article, we derive and analyze an efficient spectral method based on the operational matrices of three dimensional orthogonal Jacobi polynomials to solve numerically the mixed partial derivatives type multi-terms high dimensions generalized class of fractional order partial differential equations. We transform the considered fractional order problem to an easily solvable algebraic equations with the aid of the operational matrices. Being easily solvable, the associated algebraic system leads to finding the solution of the problem. Some test problems are considered to confirm the accuracy and validity of the proposed numerical method. The convergence of the method is ensured by comparing our Matlab software simulations based obtained results with the exact solutions in the literature, yielding negligible errors. Moreover, comparative results discussed in the literature are extended and improved in this study.

  2. Numerical Schemes for the Hamilton-Jacobi and Level Set Equations on Triangulated Domains

    NASA Technical Reports Server (NTRS)

    Barth, Timothy J.; Sethian, James A.

    1997-01-01

    Borrowing from techniques developed for conservation law equations, numerical schemes which discretize the Hamilton-Jacobi (H-J), level set, and Eikonal equations on triangulated domains are presented. The first scheme is a provably monotone discretization for certain forms of the H-J equations. Unfortunately, the basic scheme lacks proper Lipschitz continuity of the numerical Hamiltonian. By employing a virtual edge flipping technique, Lipschitz continuity of the numerical flux is restored on acute triangulations. Next, schemes are introduced and developed based on the weaker concept of positive coefficient approximations for homogeneous Hamiltonians. These schemes possess a discrete maximum principle on arbitrary triangulations and naturally exhibit proper Lipschitz continuity of the numerical Hamiltonian. Finally, a class of Petrov-Galerkin approximations are considered. These schemes are stabilized via a least-squares bilinear form. The Petrov-Galerkin schemes do not possess a discrete maximum principle but generalize to high order accuracy.

  3. The 10-Item Connor-Davidson Resilience Scale: Factorial Structure, Reliability, Validity, and Correlates Among Student Nurses in Southwestern Nigeria.

    PubMed

    Aloba, Olutayo; Olabisi, Oluseyi; Aloba, Tolulope

    2016-01-01

    The 10-item Connor-Davidson Resilience Scale (CD-RISC) has demonstrated satisfactory psychometric properties as a measure of resilience in all the previous studies conducted in developed countries. The objective of this study was to explore the psychometric characteristics of the 10-item CD-RISC among students nurses in southwestern Nigeria. This descriptive cross-sectional study involved a total of 449 student nurses who completed the 10-item CD-RISC in addition to measures of self-esteem, depression, religiosity, and psychological distress. The scale demonstrated adequate reliability (Cronbach's α = .81) and satisfactory validity with significant correlations with the measures of self-esteem, depression, religiosity, and psychological distress. Factor analyses revealed that resilience was best explained by a two-factor construct. The scale is a valid measure of resilience among Nigerian student nurses. © The Author(s) 2016.

  4. Morphological and molecular review of Jacob's Mountain Stream Keelback Opisthotropis jacobi Angel Bourret, 1933 (Squamata: Natricidae) with description of a sibling species from northern Vietnam.

    PubMed

    Ziegler, Thomas; David, Patrick; Ziegler, Tim N; Pham, Cuong T; Nguyen, Truong Q; Le, Minh D

    2018-01-21

    New morphological data including hemipenis morphology is provided for Opisthotropis jacobi, a poorly known Mountain Stream Keelback from Vietnam and China, based on three newly collected individuals from Sa Pa (Lao Cai Province) and Tam Dao (Vinh Phuc Province) in northern Vietnam. In addition, morphological data from Vietnam is summarized based on the original description (Angel Bourret 1933), on the overview book by Bourret (1936) and on a number of smaller, little-known contributions by the latter author along with re-examination of specimens deposited in the herpetological collection of the Muséum national d'Histoire naturelle, Paris. We also sequenced a fragment of the mitochondrial cytochrome b from the newly collected specimens of the Jacob's Mountain Stream Keelback and performed molecular analyses of new and existing data of the genus. A recently discovered Opisthotropis population from Tay Yen Tu Nature Reserve in Bac Giang Province, northern Vietnam, which at the first glance resembled O. jacobi morphologically, is shown to diverge both genetically and morphologically from the existing species and is herein described as a new species. Opisthotropis voquyi sp. nov. is characterized by the combination of the following characters: internasal not in contact with loreal; one preocular; usually two postoculars; one anterior temporal; one posterior temporal; 7 or 8, rarely 9 supralabials; 25 maxillary teeth; subcaudals 74-86; 15 dorsal scale rows at neck, at midbody and before vent; body scales smooth or only with few faint keels; and dorsal scales being greyish, greyish-brown or brown in preservative, posteriorly more or less edged with pale greyish-brown. Phylogenetically, the new species is supported as a sister taxon to O. jacobi, but the two taxa are approximately 10% divergent based on cytochrome b data.

  5. Invariants of the Jacobi-Porstendorfer room model for radon progeny in indoor air.

    PubMed

    Thomas, Josef; Jilek, Karel

    2012-06-01

    The Jacobi-Porstendörfer room model, describing the dynamical behaviour of radon and radon progeny in indoor air, has been successfully used for decades. The inversion of the model-the determination of the five parameters from measured results which provide better information on the room environment than mere ratios of unattached and attached radon progeny-is treated as an algebraic task. The linear interdependence of the used equations strongly limits the algebraic invertibility of experimental results. For a unique solution, the fulfilment of two invariants of the room model for the measured results is required. Non-fulfilment of these model invariants by the measured results leads to a set of non-identical solutions and indicates the violation of the conditions required by the room model or the incorrectness or excessive uncertainties of the measured results. The limited and non-unique algebraic invertibility of the room model is analysed numerically using our own data for the radon progeny.

  6. Inhomogeneous Jacobi equation for minimal surfaces and perturbative change in holographic entanglement entropy

    NASA Astrophysics Data System (ADS)

    Ghosh, Avirup; Mishra, Rohit

    2018-04-01

    The change in holographic entanglement entropy (HEE) for small fluctuations about pure anti-de Sitter (AdS) is obtained by a perturbative expansion of the area functional in terms of the change in the bulk metric and the embedded extremal surface. However it is known that change in the embedding appears at second order or higher. It was shown that these changes in the embedding can be calculated in the 2 +1 dimensional case by solving a "generalized geodesic deviation equation." We generalize this result to arbitrary dimensions by deriving an inhomogeneous form of the Jacobi equation for minimal surfaces. The solutions of this equation map a minimal surface in a given space time to a minimal surface in a space time which is a perturbation over the initial space time. Using this we perturbatively calculate the changes in HEE up to second order for boosted black brane like perturbations over AdS4.

  7. 1985 Update of Materials in the Sarah K. Davidson Family-Patient Health Education Library with Addresses of Publishers of All Listings, and Addresses of Resources from Which Pamphlets and Fact Sheets Are Available.

    ERIC Educational Resources Information Center

    Stevenson, Betty Satterwhite, Ed.

    This update of a bibliography published in 1981 lists selected holdings of the Sarah K. Davidson Family-Patient Library, which is located in the Strong Memorial Hospital of the University of Rochester (New York); it is intended for use with the original bibliography. To aid in ordering books and seeking further information on various topics, this…

  8. Psychometric validation of the French version of the Connor-Davidson Resilience Scale.

    PubMed

    Guihard, G; Deumier, L; Alliot-Licht, B; Bouton-Kelly, L; Michaut, C; Quilliot, F

    2018-02-01

    Resilience defines the ability to face adversity with positive outcomes. Different scales, including the 25-item Connor-Davidson Resilience Scale (CDRISC), have been elaborated in order to evaluate resilience among various populations. The evaluation of resilience in French populations was impossible until CDRISC was translated into French. In the present work, we aim to validate a French version of CDRISC (f-CDRISC). The survey was conducted at Nantes University. Both dental and medical students were eligible. The factor structure of f-CDRISC was determined and its replicability was tested on two sub-samples by exploratory factor analysis (EFA) and parallel analysis (PA). A third student sample was used for confirmatory factorial analysis (CFA). We collected 1210 responses. Four items did not reach acceptance thresholds for reliability and were discarded from the f-CDRISC. EFA and PA of the remaining 21 items highlighted a replicable 3-factor structure that was further confirmed by CFA. Resilience factors included "tolerance to negative affects", "tenacity" and "self-confidence". All factors displayed acceptable to good internal consistency. They were characterized by positive medium to strong correlations with the overall f-CDRISC Scale. Significant positive correlations were also observed between the resilience factors. The present work constitutes the first study devoted to a French adaptation of the CDRISC questionnaire. We present evidence showing that the f-CDRISC is a reliable tool for resilience evaluation in French speaking populations. Copyright © 2017 L'Encéphale, Paris. Published by Elsevier Masson SAS. All rights reserved.

  9. Constants of the motion, universal time and the Hamilton-Jacobi function in general relativity

    NASA Astrophysics Data System (ADS)

    O'Hara, Paul

    2013-04-01

    In most text books of mechanics, Newton's laws or Hamilton's equations of motion are first written down and then solved based on initial conditions to determine the constants of the motions and to describe the trajectories of the particles. In this essay, we take a different starting point. We begin with the metrics of general relativity and show how they can be used to construct by inspection constants of motion, which can then be used to write down the equations of the trajectories. This will be achieved by deriving a Hamiltonian-Jacobi function from the metric and showing that its existence requires all of the above mentioned properties. The article concludes by showing that a consistent theory of such functions also requires the need for a universal measure of time which can be identified with the "worldtime" parameter, first introduced by Steuckelberg and later developed by Horwitz and Piron.

  10. End of Life Disposal for Three Libration Point Missions through Manipulation of the Jacobi Constant and Zero Velocity Curves

    NASA Technical Reports Server (NTRS)

    Peterson, Jeremy D.; Brown, Jonathan M.

    2015-01-01

    The aim of this investigation is to determine the feasibility of mission disposal by inserting the spacecraft into a heliocentric orbit along the unstable manifold and then manipulating the Jacobi constant to prevent the spacecraft from returning to the Earth-Moon system. This investigation focuses around L1 orbits representative of ACE, WIND, and SOHO. It will model the impulsive delta-V necessary to close the zero velocity curves after escape through the L1 gateway in the circular restricted three body model and also include full ephemeris force models and higher fidelity finite maneuver models for the three spacecraft.

  11. Hamilton-Jacobi modelling of relative motion for formation flying.

    PubMed

    Kolemen, Egemen; Kasdin, N Jeremy; Gurfil, Pini

    2005-12-01

    A precise analytic model for the relative motion of a group of satellites in slightly elliptic orbits is introduced. With this aim, we describe the relative motion of an object relative to a circular or slightly elliptic reference orbit in the rotating Hill frame via a low-order Hamiltonian, and solve the Hamilton-Jacobi equation. This results in a first-order solution to the relative motion identical to the Clohessy-Wiltshire approach; here, however, rather than using initial conditions as our constants of the motion, we utilize the canonical momenta and coordinates. This allows us to treat perturbations in an identical manner, as in the classical Delaunay formulation of the two-body problem. A precise analytical model for the base orbit is chosen with the included effect of zonal harmonics (J(2), J(3), J(4)). A Hamiltonian describing the real relative motion is formed and by differing this from the nominal Hamiltonian, the perturbing Hamiltonian is obtained. Using the Hamilton equations, the variational equations for the new constants are found. In a manner analogous to the center manifold reduction procedure, the non-periodic part of the motion is canceled through a magnitude analysis leading to simple boundedness conditions that cancel the drift terms due to the higher order perturbations. Using this condition, the variational equations are integrated to give periodic solutions that closely approximate the results from numerical integration (1 mm/per orbit for higher order and eccentricity perturbations and 30 cm/per orbit for zonal perturbations). This procedure provides a compact and insightful analytic description of the resulting relative motion.

  12. Diarrheagenic Escherichia coli and Acute Gastroenteritis in Children in Davidson County, Tennessee, United States: A Case-control Study.

    PubMed

    Imdad, Aamer; Foster, Monique A; Iqbal, Junaid; Fonnesbeck, Christopher; Payne, Daniel C; Zhang, Chengxian; Chappell, James D; Halasa, Natasha; Gómez-Duarte, Oscar G

    2018-06-01

    Diarrheagenic Escherichia coli (DEC) is an important cause of acute gastroenteritis in children; however, there is limited information available on the epidemiology, phylogenetics, serotyping and antibiotic susceptibility of DEC in children in the United States. The aim of this study was to determine the molecular epidemiology of DEC among children with and without acute gastroenteritis in Davidson County, Tennessee. This prospective, frequency matched, case-control study recruited subjects 15 days to 17 years of age and detected DEC with polymerase chain reaction from stool samples. Additional testing was done to define phylogenetics and antibiotics resistance. Among 1267 participants, 857 cases and 410 controls, 5.5% were positive for at least one subtype of DEC. Enteroaggregative E. coli [n = 32 (45%)] was the most common subtype followed by enteropathogenic E. coli (EPEC) [n = 30 (43%)], Shiga toxin-producing E. coli [n = 4 (6%)] and diffusely adherent E. coli [n = 4 (6%)]. No significant difference in prevalence of DEC was found between cases (5%) and controls (7%) [odds ratio: 0.66 (95% confidence interval: 0.4-1.07)], and results were similar when data were stratified by subtypes and adjusted for age, sex, race and ethnicity. Substantial diversity was found among DEC isolates in terms of phylotypes and serotypes, and a large proportion was resistant to, at least, one antibiotic. Enteroaggregative E. coli and enteropathogenic E. coli were frequently found in both cases and controls in this study population. DNA-based methods for detection of these subtypes need further investigation to help differentiate between pathogenic and colonizing strains.

  13. Tensor products of U{sub q}{sup Prime }sl-caret(2)-modules and the big q{sup 2}-Jacobi function transform

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gade, R. M.

    2013-01-15

    Four tensor products of evaluation modules of the quantum affine algebra U{sub q}{sup Prime }sl-caret(2) obtained from the negative and positive series, the complementary and the strange series representations are investigated. Linear operators R(z) satisfying the intertwining property on finite linear combinations of the canonical basis elements of the tensor products are described in terms of two sets of infinite sums {l_brace}{tau}{sup (r,t)}{r_brace}{sub r,t Element-Of Z{sub {>=}{sub 0}}} and {l_brace}{tau}{sup (r,t)}{r_brace}{sub r,t Element-Of Z{sub {>=}{sub 0}}} involving big q{sup 2}-Jacobi functions or related nonterminating basic hypergeometric series. Inhomogeneous recurrence relations can be derived for both sets. Evaluations of the simplestmore » sums provide the corresponding initial conditions. For the first set of sums the relations entail a big q{sup 2}-Jacobi function transform pair. An integral decomposition is obtained for the sum {tau}{sup (r,t)}. A partial description of the relation between the decompositions of the tensor products with respect to U{sub q}sl(2) or with respect to its complement in U{sub q}{sup Prime }sl-caret(2) can be formulated in terms of Askey-Wilson function transforms. For a particular combination of two tensor products, the occurrence of proper U{sub q}{sup Prime }sl-caret(2)-submodules is discussed.« less

  14. Iterative Methods for the Non-LTE Transfer of Polarized Radiation: Resonance Line Polarization in One-dimensional Atmospheres

    NASA Astrophysics Data System (ADS)

    Trujillo Bueno, Javier; Manso Sainz, Rafael

    1999-05-01

    This paper shows how to generalize to non-LTE polarization transfer some operator splitting methods that were originally developed for solving unpolarized transfer problems. These are the Jacobi-based accelerated Λ-iteration (ALI) method of Olson, Auer, & Buchler and the iterative schemes based on Gauss-Seidel and successive overrelaxation (SOR) iteration of Trujillo Bueno and Fabiani Bendicho. The theoretical framework chosen for the formulation of polarization transfer problems is the quantum electrodynamics (QED) theory of Landi Degl'Innocenti, which specifies the excitation state of the atoms in terms of the irreducible tensor components of the atomic density matrix. This first paper establishes the grounds of our numerical approach to non-LTE polarization transfer by concentrating on the standard case of scattering line polarization in a gas of two-level atoms, including the Hanle effect due to a weak microturbulent and isotropic magnetic field. We begin demonstrating that the well-known Λ-iteration method leads to the self-consistent solution of this type of problem if one initializes using the ``exact'' solution corresponding to the unpolarized case. We show then how the above-mentioned splitting methods can be easily derived from this simple Λ-iteration scheme. We show that our SOR method is 10 times faster than the Jacobi-based ALI method, while our implementation of the Gauss-Seidel method is 4 times faster. These iterative schemes lead to the self-consistent solution independently of the chosen initialization. The convergence rate of these iterative methods is very high; they do not require either the construction or the inversion of any matrix, and the computing time per iteration is similar to that of the Λ-iteration method.

  15. The validity and diagnostic efficiency of the Davidson Trauma Scale in military veterans who have served since September 11th, 2001.

    PubMed

    McDonald, Scott D; Beckham, Jean C; Morey, Rajendra A; Calhoun, Patrick S

    2009-03-01

    The present study examined the psychometric properties and diagnostic efficiency of the Davidson Trauma Scale (DTS), a self-report measure of posttraumatic stress disorder (PTSD) symptoms. Participants included 158 U.S. military veterans who have served since September 11, 2001 (post-9/11). Results support the DTS as a valid self-report measure of PTSD symptoms. The DTS demonstrated good internal consistency, concurrent validity, and convergent and divergent validity. Diagnostic efficiency was excellent when discriminating between veterans with PTSD and veterans with no Axis I diagnosis. However, although satisfactory by conventional standards, efficiency was substantially attenuated when discriminating between PTSD and other Axis I diagnoses. Thus, results illustrate that potency of the DTS as a diagnostic aid was highly dependent on the comparison group used for analyses. Results are discussed in terms of applications to clinical practice and research.

  16. Generalizations of the Alternating Direction Method of Multipliers for Large-Scale and Distributed Optimization

    DTIC Science & Technology

    2014-05-01

    exact one is solved later — as- signed as step 5 of Algorithm 2 — because at each iteration , the ADMM updates the variables in the Gauss - Seidel ...Jacobi ADMM (see Algo- rithm 5 below). Unlike the Gauss - Seidel ADMM, the Jacobi ADMM updates all the 70 blocks in parallel at every iteration : xk+1i...that extending ADMM straightforwardly from the classic Gauss - Seidel setting to the Jacobi setting, from two blocks to multiple blocks, will preserve

  17. Serre duality, Abel's theorem, and Jacobi inversion for supercurves over a thick superpoint

    NASA Astrophysics Data System (ADS)

    Rothstein, Mitchell J.; Rabin, Jeffrey M.

    2015-04-01

    The principal aim of this paper is to extend Abel's theorem to the setting of complex supermanifolds of dimension 1 | q over a finite-dimensional local supercommutative C-algebra. The theorem is proved by establishing a compatibility of Serre duality for the supercurve with Poincaré duality on the reduced curve. We include an elementary algebraic proof of the requisite form of Serre duality, closely based on the account of the reduced case given by Serre in Algebraic groups and class fields, combined with an invariance result for the topology on the dual of the space of répartitions. Our Abel map, taking Cartier divisors of degree zero to the dual of the space of sections of the Berezinian sheaf, modulo periods, is defined via Penkov's characterization of the Berezinian sheaf as the cohomology of the de Rham complex of the sheaf D of differential operators. We discuss the Jacobi inversion problem for the Abel map and give an example demonstrating that if n is an integer sufficiently large that the generic divisor of degree n is linearly equivalent to an effective divisor, this need not be the case for all divisors of degree n.

  18. Iterative Methods for Solving Nonlinear Parabolic Problem in Pension Saving Management

    NASA Astrophysics Data System (ADS)

    Koleva, M. N.

    2011-11-01

    In this work we consider a nonlinear parabolic equation, obtained from Riccati like transformation of the Hamilton-Jacobi-Bellman equation, arising in pension saving management. We discuss two numerical iterative methods for solving the model problem—fully implicit Picard method and mixed Picard-Newton method, which preserves the parabolic characteristics of the differential problem. Numerical experiments for comparison the accuracy and effectiveness of the algorithms are discussed. Finally, observations are given.

  19. Multigrid method for stability problems

    NASA Technical Reports Server (NTRS)

    Taasan, Shlomo

    1988-01-01

    The problem of calculating the stability of steady state solutions of differential equations is treated. Leading eigenvalues (i.e., having maximal real part) of large matrices that arise from discretization are to be calculated. An efficient multigrid method for solving these problems is presented. The method begins by obtaining an initial approximation for the dominant subspace on a coarse level using a damped Jacobi relaxation. This proceeds until enough accuracy for the dominant subspace has been obtained. The resulting grid functions are then used as an initial approximation for appropriate eigenvalue problems. These problems are being solved first on coarse levels, followed by refinement until a desired accuracy for the eigenvalues has been achieved. The method employs local relaxation on all levels together with a global change on the coarsest level only, which is designed to separate the different eigenfunctions as well as to update their corresponding eigenvalues. Coarsening is done using the FAS formulation in a non-standard way in which the right hand side of the coarse grid equations involves unknown parameters to be solved for on the coarse grid. This in particular leads to a new multigrid method for calculating the eigenvalues of symmetric problems. Numerical experiments with a model problem demonstrate the effectiveness of the method proposed. Using an FMG algorithm a solution to the level of discretization errors is obtained in just a few work units (less than 10), where a work unit is the work involved in one Jacobi relization on the finest level.

  20. Projection methods for line radiative transfer in spherical media.

    NASA Astrophysics Data System (ADS)

    Anusha, L. S.; Nagendra, K. N.

    An efficient numerical method called the Preconditioned Bi-Conjugate Gradient (Pre-BiCG) method is presented for the solution of radiative transfer equation in spherical geometry. A variant of this method called Stabilized Preconditioned Bi-Conjugate Gradient (Pre-BiCG-STAB) is also presented. These methods are based on projections on the subspaces of the n dimensional Euclidean space mathbb {R}n called Krylov subspaces. The methods are shown to be faster in terms of convergence rate compared to the contemporary iterative methods such as Jacobi, Gauss-Seidel and Successive Over Relaxation (SOR).

  1. Numerical Grid Generation and Potential Airfoil Analysis and Design

    DTIC Science & Technology

    1988-01-01

    Gauss- Seidel , SOR and ADI iterative methods e JACOBI METHOD In the Jacobi method each new value of a function is computed entirely from old values...preceding iteration and adding the inhomogeneous (boundary condition) term. * GAUSS- SEIDEL METHOD When we compute I in a Jacobi method, we have already...Gauss- Seidel method. Sufficient condition for p convergence of the Gauss- Seidel method is diagonal-dominance of [A].9W e SUCESSIVE OVER-RELAXATION (SOR

  2. A program for the fitting of Debye, Cole-Cole, Cole-Davidson, and Havriliak-Negami dispersions to dielectric data.

    PubMed

    Grosse, Constantino

    2014-04-01

    The description and interpretation of dielectric spectroscopy data usually require the use of analytical functions, which include unknown parameters that must be determined iteratively by means of a fitting procedure. This is not a trivial task and much effort has been spent to find the best way to accomplish it. While the theoretical approach based on the Levenberg-Marquardt algorithm is well known, no freely available program specifically adapted to the dielectric spectroscopy problem exists to the best of our knowledge. Moreover, even the more general commercial packages usually fail on the following aspects: (1) allow to keep temporarily fixed some of the parameters, (2) allow to freely specify the uncertainty values for each data point, (3) check that parameter values fall within prescribed bounds during the fitting process, and (4) allow to fit either the real, or the imaginary, or simultaneously both parts of the complex permittivity. A program that satisfies all these requirements and allows fitting any superposition of the Debye, Cole-Cole, Cole-Davidson, and Havriliak-Negami dispersions plus a conductivity term to measured dielectric spectroscopy data is presented. It is available on request from the author. Copyright © 2013 Elsevier Inc. All rights reserved.

  3. Modifications of the PCPT method for HJB equations

    NASA Astrophysics Data System (ADS)

    Kossaczký, I.; Ehrhardt, M.; Günther, M.

    2016-10-01

    In this paper we will revisit the modification of the piecewise constant policy timestepping (PCPT) method for solving Hamilton-Jacobi-Bellman (HJB) equations. This modification is called piecewise predicted policy timestepping (PPPT) method and if properly used, it may be significantly faster. We will quickly recapitulate the algorithms of PCPT, PPPT methods and of the classical implicit method and apply them on a passport option pricing problem with non-standard payoff. We will present modifications needed to solve this problem effectively with the PPPT method and compare the performance with the PCPT method and the classical implicit method.

  4. Reliability and validity of the Khmer version of the 10-item Connor-Davidson Resilience Scale (Kh-CD-RISC10) in Cambodian adolescents.

    PubMed

    Duong, Chanmettachampavieng; Hurst, Cameron P

    2016-06-08

    Resilience has been characterized as a defensive factor against the refinement of mental health problems. This study adapted the Connor-Davidson Resilience Scale (Kh-CD-RISC10) for use in Khmer adolescents and subsequently investigates its psychometric properties. Using stratified random sampling, this cross-sectional study sampled Cambodian adolescents from high schools selected randomly within three provinces (Phnom Penh, Battambang and Mondulkiri)-location (rural, urban) combinations. Parallel analysis was used to identify the number of component(s), and the structure of the single factor was subsequently explored using principal axis factoring. A confirmatory factor analysis was then performed to establish the fit of the Kh-CD-RISC10 to another sample. To assess convergent validity, the factor scores of the Khmer version of Connor-Davidson Resilience Scale were categorized into three levels, and then the general negative affectivity (GNA) and physiological hyperarousal (PH) scales (derived from the DASS 21) were compared among the three resilience groups. Of the 798 participants who responded (responded rate = 82.26 %), 440 (41.23 %) were female and the age ranged from 14 to 24 years old (mean = 17.36, SD = 1.325). The internal consistency of the Khmer 10-item CD-RISC was also shown to be high in Cambodian adolescents (Cronbach's alpha = 0. 82). Confirmatory factor analysis revealed the single factor model fit data adequately (χ(2) = 100.103, df = 35, p < 0.001, CFI = 0.9484, RMSEA = 0.0384). We found that there were significant differences in both General Negative affectivity and Physiological Hyperarousal among the three resilience groups (FGNA = 12. 84, df = 2, p < 0.001; FPH = 13. 01, df = 2, p < 0.001). The results from the present study indicate that the Khmer version of CD-RISC shows good psychometric properties in Cambodian adolescents. Our result confirms that a single dimension underlay the 10 items on the CD

  5. Spanish validation of the 10-item Connor-Davidson Resilience Scale (CD-RISC 10) with non-professional caregivers.

    PubMed

    Blanco, Vanessa; Guisande, María Adelina; Sánchez, María Teresa; Otero, Patricia; Vázquez, Fernando L

    2017-11-08

    Despite the importance of resilience in populations under stress, and the fact that the 10-item version Connor-Davidson Resilience Scale (CD-RISC 10) is the shortest instrument for reliable and valid evaluation of resilience, there are no data on their psychometric properties in non-professional caregivers. The aim of this study was to analyze the psychometric properties and factorial structure of the spanish version of the CD-RISC 10 in non-professional caregivers. Independently trained assessors evaluated resilience, self-esteem, social support, emotional distress and depression in a sample of 294 caregivers (89.8% women, mean age 55.3 years). The internal consistency of CD-RISC 10 was α = .86. A single factor was found that accounted for 44.7% of the total variance. Confirmatory factor analysis corroborated this unifactorial model. The CD-RISC 10 was significantly correlated with the self-esteem (r = .416, p < .001) and social support (r = .228, p < .001) scales, and the emotional distress scale (r = -.311, p < .001), though this was an inverse relationship. A score ≤ 23 was a suitable cut-off point for discriminating caregivers with depression (sensitivity = 70.0%, specificity = 68.2%). The CD-RISC 10 is a reliable and valid instrument to evaluate resilience in the caregiver population.

  6. A cubic scaling algorithm for excited states calculations in particle-particle random phase approximation

    NASA Astrophysics Data System (ADS)

    Lu, Jianfeng; Yang, Haizhao

    2017-07-01

    The particle-particle random phase approximation (pp-RPA) has been shown to be capable of describing double, Rydberg, and charge transfer excitations, for which the conventional time-dependent density functional theory (TDDFT) might not be suitable. It is thus desirable to reduce the computational cost of pp-RPA so that it can be efficiently applied to larger molecules and even solids. This paper introduces an O (N3) algorithm, where N is the number of orbitals, based on an interpolative separable density fitting technique and the Jacobi-Davidson eigensolver to calculate a few low-lying excitations in the pp-RPA framework. The size of the pp-RPA matrix can also be reduced by keeping only a small portion of orbitals with orbital energy close to the Fermi energy. This reduced system leads to a smaller prefactor of the cubic scaling algorithm, while keeping the accuracy for the low-lying excitation energies.

  7. Bending space-time: a commentary on Dyson, Eddington and Davidson (1920) 'A determination of the deflection of light by the Sun's gravitational field'.

    PubMed

    Longair, Malcolm

    2015-04-13

    The famous eclipse expedition of 1919 to Sobral, Brazil, and the island of Principe, in the Gulf of Guinea, led by Dyson, Eddington and Davidson was a turning point in the history of relativity, not only because of its importance as a test of Einstein's General Theory of Relativity, but also because of the intense public interest which was aroused by the success of the expedition. The dramatic sequence of events which occurred is reviewed, as well as the long-term impact of its success. The gravitational bending of electromagnetic waves by massive bodies is a subject of the greatest importance for contemporary and future astronomy, astrophysics and cosmology. Examples of the potential impact of this key tool of modern observational astronomy are presented. This commentary was written to celebrate the 350th anniversary of the journal Philosophical Transactions of the Royal Society.

  8. Calculations of the excitation energies of all-trans and 11,12s-dicis retinals using localized molecular orbitals obtained by the elongation method

    NASA Astrophysics Data System (ADS)

    Kurihara, Youji; Aoki, Yuriko; Imamura, Akira

    1997-09-01

    In the present article, the excitation energies of the all-trans and the 11,12s-dicis retinals were calculated by using the elongation method. The geometries of these molecules were optimized with the 4-31G basis set by using the GAUSSIAN 92 program. The wave functions for the calculation of the excitation energies were obtained with CNDO/S approximation by the elongation method, which enables us to analyze electronic structures of aperiodic polymers in terms of the exciton-type local excitation and the charge transfer-type excitation. The excitation energies were calculated by using the single excitation configuration interaction (SECI) on the basis of localized molecular orbitals (LMOs). The LMOs were obtained in the process of the elongation method. The configuration interaction (CI) matrices were diagonalized by Davidson's method. The calculated results were in good agreement with the experimental data for absorption spectra. In order to consider the isomerization path from 11,12s-dicis to all-trans retinals, the barriers to the rotations about C11-C12 double and C12-C13 single bonds were evaluated.

  9. Ordering Unstructured Meshes for Sparse Matrix Computations on Leading Parallel Systems

    NASA Technical Reports Server (NTRS)

    Oliker, Leonid; Li, Xiaoye; Heber, Gerd; Biswas, Rupak

    2000-01-01

    The ability of computers to solve hitherto intractable problems and simulate complex processes using mathematical models makes them an indispensable part of modern science and engineering. Computer simulations of large-scale realistic applications usually require solving a set of non-linear partial differential equations (PDES) over a finite region. For example, one thrust area in the DOE Grand Challenge projects is to design future accelerators such as the SpaHation Neutron Source (SNS). Our colleagues at SLAC need to model complex RFQ cavities with large aspect ratios. Unstructured grids are currently used to resolve the small features in a large computational domain; dynamic mesh adaptation will be added in the future for additional efficiency. The PDEs for electromagnetics are discretized by the FEM method, which leads to a generalized eigenvalue problem Kx = AMx, where K and M are the stiffness and mass matrices, and are very sparse. In a typical cavity model, the number of degrees of freedom is about one million. For such large eigenproblems, direct solution techniques quickly reach the memory limits. Instead, the most widely-used methods are Krylov subspace methods, such as Lanczos or Jacobi-Davidson. In all the Krylov-based algorithms, sparse matrix-vector multiplication (SPMV) must be performed repeatedly. Therefore, the efficiency of SPMV usually determines the eigensolver speed. SPMV is also one of the most heavily used kernels in large-scale numerical simulations.

  10. [Molecular typing methods for Pasteurella multocida-A review].

    PubMed

    Peng, Zhong; Liang, Wan; Wu, Bin

    2016-10-04

    Pasteurella multocida is an important gram-negative pathogenic bacterium that could infect wide ranges of animals. Humans could also be infected by P. multocida via animal bite or scratching. Current typing methods for P. multocida include serological typing methods and molecular typing methods. Of them, serological typing methods are based on immunological assays, which are too complicated for clinical bacteriological studies. However, the molecular methods including multiple PCRs and multilocus sequence typing (MLST) methods are more suitable for bacteriological studies of P. multocida in clinic, with their simple operation, high efficiency and accurate detection compared to the traditional serological typing methods, they are therefore widely used. In the current review, we briefly describe the molecular typing methods for P. multocida. Our aim is to provide a knowledge-foundation for clinical bacteriological investigation especially the molecular investigation for P. multocida.

  11. Full-dimensional vibrational calculations of five-atom molecules using a combination of Radau and Jacobi coordinates: Applications to methane and fluoromethane

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhao, Zhiqiang; Chen, Jun; University of Chinese Academy of Sciences, Beijing 100049

    Full quantum mechanical calculations of vibrational energies of methane and fluoromethane are carried out using a polyspherical description combining Radau and Jacobi coordinates. The Hamiltonian is built in a potential-optimized discrete variable representation, and vibrational energies are solved using an iterative eigensolver. This new approach can be applied to a large variety of molecules. In particular, we show that it is able to accurately and efficiently compute eigenstates for four different molecules : CH{sub 4}, CHD{sub 3}, CH{sub 2}D{sub 2}, and CH{sub 3}F. Very good agreement is obtained with the results reported previously in the literature with different approaches andmore » with experimental data.« less

  12. Collective motion in prolate γ-rigid nuclei within minimal length concept via a quantum perturbation method

    NASA Astrophysics Data System (ADS)

    Chabab, M.; El Batoul, A.; Lahbas, A.; Oulne, M.

    2018-05-01

    Based on the minimal length concept, inspired by Heisenberg algebra, a closed analytical formula is derived for the energy spectrum of the prolate γ-rigid Bohr-Mottelson Hamiltonian of nuclei, within a quantum perturbation method (QPM), by considering a scaled Davidson potential in β shape variable. In the resulting solution, called X(3)-D-ML, the ground state and the first β-band are all studied as a function of the free parameters. The fact of introducing the minimal length concept with a QPM makes the model very flexible and a powerful approach to describe nuclear collective excitations of a variety of vibrational-like nuclei. The introduction of scaling parameters in the Davidson potential enables us to get a physical minimum of this latter in comparison with previous works. The analysis of the corrected wave function, as well as the probability density distribution, shows that the minimal length parameter has a physical upper bound limit.

  13. Axisymmetric black holes allowing for separation of variables in the Klein-Gordon and Hamilton-Jacobi equations

    NASA Astrophysics Data System (ADS)

    Konoplya, R. A.; Stuchlík, Z.; Zhidenko, A.

    2018-04-01

    We determine the class of axisymmetric and asymptotically flat black-hole spacetimes for which the test Klein-Gordon and Hamilton-Jacobi equations allow for the separation of variables. The known Kerr, Kerr-Newman, Kerr-Sen and some other black-hole metrics in various theories of gravity are within the class of spacetimes described here. It is shown that although the black-hole metric in the Einstein-dilaton-Gauss-Bonnet theory does not allow for the separation of variables (at least in the considered coordinates), for a number of applications it can be effectively approximated by a metric within the above class. This gives us some hope that the class of spacetimes described here may be not only generic for the known solutions allowing for the separation of variables, but also a good approximation for a broader class of metrics, which does not admit such separation. Finally, the generic form of the axisymmetric metric is expanded in the radial direction in terms of the continued fractions and the connection with other black-hole parametrizations is discussed.

  14. Measuring Ambiguity in HLA Typing Methods

    PubMed Central

    Madbouly, Abeer; Freeman, John; Maiers, Martin

    2012-01-01

    In hematopoietic stem cell transplantation, donor selection is based primarily on matching donor and patient HLA genes. These genes are highly polymorphic and their typing can result in exact allele assignment at each gene (the resolution at which patients and donors are matched), but it can also result in a set of ambiguous assignments, depending on the typing methodology used. To facilitate rapid identification of matched donors, registries employ statistical algorithms to infer HLA alleles from ambiguous genotypes. Linkage disequilibrium information encapsulated in haplotype frequencies is used to facilitate prediction of the most likely haplotype assignment. An HLA typing with less ambiguity produces fewer high-probability haplotypes and a more reliable prediction. We estimated ambiguity for several HLA typing methods across four continental populations using an information theory-based measure, Shannon's entropy. We used allele and haplotype frequencies to calculate entropy for different sets of 1,000 subjects with simulated HLA typing. Using allele frequencies we calculated an average entropy in Caucasians of 1.65 for serology, 1.06 for allele family level, 0.49 for a 2002-era SSO kit, and 0.076 for single-pass SBT. When using haplotype frequencies in entropy calculations, we found average entropies of 0.72 for serology, 0.73 for allele family level, 0.05 for SSO, and 0.002 for single-pass SBT. Application of haplotype frequencies further reduces HLA typing ambiguity. We also estimated expected confirmatory typing mismatch rates for simulated subjects. In a hypothetical registry with all donors typed using the same method, the entropy values based on haplotype frequencies correspond to confirmatory typing mismatch rates of 1.31% for SSO versus only 0.08% for SBT. Intermediate-resolution single-pass SBT contains the least ambiguity of the methods we evaluated and therefore the most certainty in allele prediction. The presented measure objectively evaluates HLA

  15. Full dimensional (15-dimensional) quantum-dynamical simulation of the protonated water-dimer III: Mixed Jacobi-valence parametrization and benchmark results for the zero point energy, vibrationally excited states, and infrared spectrum.

    PubMed

    Vendrell, Oriol; Brill, Michael; Gatti, Fabien; Lauvergnat, David; Meyer, Hans-Dieter

    2009-06-21

    Quantum dynamical calculations are reported for the zero point energy, several low-lying vibrational states, and the infrared spectrum of the H(5)O(2)(+) cation. The calculations are performed by the multiconfiguration time-dependent Hartree (MCTDH) method. A new vector parametrization based on a mixed Jacobi-valence description of the system is presented. With this parametrization the potential energy surface coupling is reduced with respect to a full Jacobi description, providing a better convergence of the n-mode representation of the potential. However, new coupling terms appear in the kinetic energy operator. These terms are derived and discussed. A mode-combination scheme based on six combined coordinates is used, and the representation of the 15-dimensional potential in terms of a six-combined mode cluster expansion including up to some 7-dimensional grids is discussed. A statistical analysis of the accuracy of the n-mode representation of the potential at all orders is performed. Benchmark, fully converged results are reported for the zero point energy, which lie within the statistical uncertainty of the reference diffusion Monte Carlo result for this system. Some low-lying vibrationally excited eigenstates are computed by block improved relaxation, illustrating the applicability of the approach to large systems. Benchmark calculations of the linear infrared spectrum are provided, and convergence with increasing size of the time-dependent basis and as a function of the order of the n-mode representation is studied. The calculations presented here make use of recent developments in the parallel version of the MCTDH code, which are briefly discussed. We also show that the infrared spectrum can be computed, to a very good approximation, within D(2d) symmetry, instead of the G(16) symmetry used before, in which the complete rotation of one water molecule with respect to the other is allowed, thus simplifying the dynamical problem.

  16. Uniform convergence of multigrid V-cycle iterations for indefinite and nonsymmetric problems

    NASA Technical Reports Server (NTRS)

    Bramble, James H.; Kwak, Do Y.; Pasciak, Joseph E.

    1993-01-01

    In this paper, we present an analysis of a multigrid method for nonsymmetric and/or indefinite elliptic problems. In this multigrid method various types of smoothers may be used. One type of smoother which we consider is defined in terms of an associated symmetric problem and includes point and line, Jacobi, and Gauss-Seidel iterations. We also study smoothers based entirely on the original operator. One is based on the normal form, that is, the product of the operator and its transpose. Other smoothers studied include point and line, Jacobi, and Gauss-Seidel. We show that the uniform estimates for symmetric positive definite problems carry over to these algorithms. More precisely, the multigrid iteration for the nonsymmetric and/or indefinite problem is shown to converge at a uniform rate provided that the coarsest grid in the multilevel iteration is sufficiently fine (but not depending on the number of multigrid levels).

  17. Bending space–time: a commentary on Dyson, Eddington and Davidson (1920) ‘A determination of the deflection of light by the Sun's gravitational field’

    PubMed Central

    Longair, Malcolm

    2015-01-01

    The famous eclipse expedition of 1919 to Sobral, Brazil, and the island of Principe, in the Gulf of Guinea, led by Dyson, Eddington and Davidson was a turning point in the history of relativity, not only because of its importance as a test of Einstein's General Theory of Relativity, but also because of the intense public interest which was aroused by the success of the expedition. The dramatic sequence of events which occurred is reviewed, as well as the long-term impact of its success. The gravitational bending of electromagnetic waves by massive bodies is a subject of the greatest importance for contemporary and future astronomy, astrophysics and cosmology. Examples of the potential impact of this key tool of modern observational astronomy are presented. This commentary was written to celebrate the 350th anniversary of the journal Philosophical Transactions of the Royal Society. PMID:25750149

  18. Burkholderia mallei Cluster 1 Type VI Secretion Mutants Exhibit Growth and Actin Polymerization Defects in RAW 264.7 Murine Macrophages

    DTIC Science & Technology

    2010-01-01

    mallei virAG; Kmr 45 pBHR4-GFP Broad-host-range vector containing gfp from pQBI T7 GFP (Quantum Biotech); Gmr 45 pBHR1-TG pBHR1 containing gfp...Bonanno, J. M. Sauder, S. Pukatzki, S. K. Burley, S. C. Almo, and J. J. Mekalanos. 2009. Type VI secretion apparatus and phage tail-associated protein...14251. 37. Pell, L. G., V. Kanelis, L. W. Donaldson, P. L. Howell, and A. R. Davidson. 2009. The phage lambda major tail protein structure reveals a

  19. Recent Observations and Structural Analysis of Surge-Type Glaciers in the Glacier Bay Area

    NASA Astrophysics Data System (ADS)

    Mayer, H.; Herzfeld, U. C.

    2003-12-01

    The Chugach-St.-Elias Mountains in North America hold the largest non-polar connected glaciated area of the world. Most of its larger glaciers are surge-type glaciers. In the summer of 2003, we collected aerial photographic and GPS data over numerous glaciers in the eastern St. Elias Mountains, including the Glacier Bay area. Observed glaciers include Davidson, Casement, McBride, Riggs, Cushing, Carroll, Rendu, Tsirku, Grand Pacific, Melbern, Ferris, Margerie, Johns Hopkins, Lamplugh, Reid, Burroughs, Morse, Muir and Willard Glaciers, of which Carroll, Rendu, Ferris, Grand Pacific, Johns Hopkins and Margerie Glaciers are surge-type glaciers. Our approach utilizes a quantitative analysis of surface patterns, following the principles of structural geology for the analysis of brittle-deformation patterns (manifested in crevasses) and ductile deformation patterns (visible in folded moraines). First results will be presented.

  20. Efficient exact-exchange time-dependent density-functional theory methods and their relation to time-dependent Hartree-Fock.

    PubMed

    Hesselmann, Andreas; Görling, Andreas

    2011-01-21

    A recently introduced time-dependent exact-exchange (TDEXX) method, i.e., a response method based on time-dependent density-functional theory that treats the frequency-dependent exchange kernel exactly, is reformulated. In the reformulated version of the TDEXX method electronic excitation energies can be calculated by solving a linear generalized eigenvalue problem while in the original version of the TDEXX method a laborious frequency iteration is required in the calculation of each excitation energy. The lowest eigenvalues of the new TDEXX eigenvalue equation corresponding to the lowest excitation energies can be efficiently obtained by, e.g., a version of the Davidson algorithm appropriate for generalized eigenvalue problems. Alternatively, with the help of a series expansion of the new TDEXX eigenvalue equation, standard eigensolvers for large regular eigenvalue problems, e.g., the standard Davidson algorithm, can be used to efficiently calculate the lowest excitation energies. With the help of the series expansion as well, the relation between the TDEXX method and time-dependent Hartree-Fock is analyzed. Several ways to take into account correlation in addition to the exact treatment of exchange in the TDEXX method are discussed, e.g., a scaling of the Kohn-Sham eigenvalues, the inclusion of (semi)local approximate correlation potentials, or hybrids of the exact-exchange kernel with kernels within the adiabatic local density approximation. The lowest lying excitations of the molecules ethylene, acetaldehyde, and pyridine are considered as examples.

  1. Approximate tensor-product preconditioners for very high order discontinuous Galerkin methods

    NASA Astrophysics Data System (ADS)

    Pazner, Will; Persson, Per-Olof

    2018-02-01

    In this paper, we develop a new tensor-product based preconditioner for discontinuous Galerkin methods with polynomial degrees higher than those typically employed. This preconditioner uses an automatic, purely algebraic method to approximate the exact block Jacobi preconditioner by Kronecker products of several small, one-dimensional matrices. Traditional matrix-based preconditioners require O (p2d) storage and O (p3d) computational work, where p is the degree of basis polynomials used, and d is the spatial dimension. Our SVD-based tensor-product preconditioner requires O (p d + 1) storage, O (p d + 1) work in two spatial dimensions, and O (p d + 2) work in three spatial dimensions. Combined with a matrix-free Newton-Krylov solver, these preconditioners allow for the solution of DG systems in linear time in p per degree of freedom in 2D, and reduce the computational complexity from O (p9) to O (p5) in 3D. Numerical results are shown in 2D and 3D for the advection, Euler, and Navier-Stokes equations, using polynomials of degree up to p = 30. For many test cases, the preconditioner results in similar iteration counts when compared with the exact block Jacobi preconditioner, and performance is significantly improved for high polynomial degrees p.

  2. Using the Kannada version of the Connor Davidson Resilience Scale to assess resilience and its relationship with psychological distress among adolescent girls in Bangalore, India.

    PubMed

    Sidheek, K P Fasli; Satyanarayana, Veena A; Sowmya, H R; Chandra, Prabha S

    2017-12-01

    A widely used and accepted scale for assessing resilience is the Connor-Davidson Resilience Scale (CD-RISC). The aim of the present study was to establish the psychometric properties of the Kannada version of the scale and assess the relationship between resilience and psychological distress in a sample of adolescent girls living in low-income settings. Data was obtained from a sample of 606 adolescent girls studying in a college meant for women from a socio-economically disadvantaged setting. The CD- RISC (25 item) was used to assess resilience and Kessler Psychological Distress Scale (K10) was used to assess psychological distress. Exploratory factor analysis yielded four stable factors instead of the original five factors. Similar results have been obtained in other factor-analytic studies. A significant negative correlation was found between psychological distress and resilience. Our study shows that the CD-RISC is a valuable measure to assess resilience among adolescents in low-income settings. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. JADAMILU: a software code for computing selected eigenvalues of large sparse symmetric matrices

    NASA Astrophysics Data System (ADS)

    Bollhöfer, Matthias; Notay, Yvan

    2007-12-01

    A new software code for computing selected eigenvalues and associated eigenvectors of a real symmetric matrix is described. The eigenvalues are either the smallest or those closest to some specified target, which may be in the interior of the spectrum. The underlying algorithm combines the Jacobi-Davidson method with efficient multilevel incomplete LU (ILU) preconditioning. Key features are modest memory requirements and robust convergence to accurate solutions. Parameters needed for incomplete LU preconditioning are automatically computed and may be updated at run time depending on the convergence pattern. The software is easy to use by non-experts and its top level routines are written in FORTRAN 77. Its potentialities are demonstrated on a few applications taken from computational physics. Program summaryProgram title: JADAMILU Catalogue identifier: ADZT_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/ADZT_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 101 359 No. of bytes in distributed program, including test data, etc.: 7 493 144 Distribution format: tar.gz Programming language: Fortran 77 Computer: Intel or AMD with g77 and pgf; Intel EM64T or Itanium with ifort; AMD Opteron with g77, pgf and ifort; Power (IBM) with xlf90. Operating system: Linux, AIX RAM: problem dependent Word size: real:8; integer: 4 or 8, according to user's choice Classification: 4.8 Nature of problem: Any physical problem requiring the computation of a few eigenvalues of a symmetric matrix. Solution method: Jacobi-Davidson combined with multilevel ILU preconditioning. Additional comments: We supply binaries rather than source code because JADAMILU uses the following external packages: MC64. This software is copyrighted software and not freely available. COPYRIGHT (c) 1999

  4. Analysis of Preconditioning and Relaxation Operators for the Discontinuous Galerkin Method Applied to Diffusion

    NASA Technical Reports Server (NTRS)

    Atkins, H. L.; Shu, Chi-Wang

    2001-01-01

    The explicit stability constraint of the discontinuous Galerkin method applied to the diffusion operator decreases dramatically as the order of the method is increased. Block Jacobi and block Gauss-Seidel preconditioner operators are examined for their effectiveness at accelerating convergence. A Fourier analysis for methods of order 2 through 6 reveals that both preconditioner operators bound the eigenvalues of the discrete spatial operator. Additionally, in one dimension, the eigenvalues are grouped into two or three regions that are invariant with order of the method. Local relaxation methods are constructed that rapidly damp high frequencies for arbitrarily large time step.

  5. Covariance Method of the Tunneling Radiation from High Dimensional Rotating Black Holes

    NASA Astrophysics Data System (ADS)

    Li, Hui-Ling; Han, Yi-Wen; Chen, Shuai-Ru; Ding, Cong

    2018-04-01

    In this paper, Angheben-Nadalini-Vanzo-Zerbini (ANVZ) covariance method is used to study the tunneling radiation from the Kerr-Gödel black hole and Myers-Perry black hole with two independent angular momentum. By solving the Hamilton-Jacobi equation and separating the variables, the radial motion equation of a tunneling particle is obtained. Using near horizon approximation and the distance of the proper pure space, we calculate the tunneling rate and the temperature of Hawking radiation. Thus, the method of ANVZ covariance is extended to the research of high dimensional black hole tunneling radiation.

  6. Gatekeeper Training in Campus Suicide Prevention

    ERIC Educational Resources Information Center

    Wallack, Cory; Servaty-Seib, Heather L.; Taub, Deborah J.

    2013-01-01

    Gatekeeper training is one of the most commonly employed methods for identifying and intervening with at-risk students (Davidson and Locke, 2010). Within the context of campus suicide prevention, a gatekeeper is broadly defined as any individual who has the potential to come into contact with at-risk students (Davidson and Locke, 2010). Although…

  7. Computational time analysis of the numerical solution of 3D electrostatic Poisson's equation

    NASA Astrophysics Data System (ADS)

    Kamboh, Shakeel Ahmed; Labadin, Jane; Rigit, Andrew Ragai Henri; Ling, Tech Chaw; Amur, Khuda Bux; Chaudhary, Muhammad Tayyab

    2015-05-01

    3D Poisson's equation is solved numerically to simulate the electric potential in a prototype design of electrohydrodynamic (EHD) ion-drag micropump. Finite difference method (FDM) is employed to discretize the governing equation. The system of linear equations resulting from FDM is solved iteratively by using the sequential Jacobi (SJ) and sequential Gauss-Seidel (SGS) methods, simulation results are also compared to examine the difference between the results. The main objective was to analyze the computational time required by both the methods with respect to different grid sizes and parallelize the Jacobi method to reduce the computational time. In common, the SGS method is faster than the SJ method but the data parallelism of Jacobi method may produce good speedup over SGS method. In this study, the feasibility of using parallel Jacobi (PJ) method is attempted in relation to SGS method. MATLAB Parallel/Distributed computing environment is used and a parallel code for SJ method is implemented. It was found that for small grid size the SGS method remains dominant over SJ method and PJ method while for large grid size both the sequential methods may take nearly too much processing time to converge. Yet, the PJ method reduces computational time to some extent for large grid sizes.

  8. A new method for correcting type I and type II constricted (cup and lop) ears.

    PubMed

    Xiaogeng, Hu; Hongxing, Zhuang; Qinghua, Yang; Haiyue, Jiang; Yanyong, Zhao

    2006-01-01

    Tanzer suggested the term "constricted ear," denoting a spectrum of deformities limited to the superior third of the ear. Tanzer classified the constricted ear into three types. Type I ears have involvement of the helix, which usually is flattened. Type II ears show involvement of both the helix and the scapha. With type III ears, the auricle is rolled into a nearly tubular form that some authors regard as a form of microtia. The authors' new method for correcting the constricted ear varies in accordance with the diverse degree of deformity. The new method was used to correct constricted ears through a one-stage operation in eight type I cases. For the remaining six type 2 cases, the methods were combined with composite grafting. Most of the patients were satisfied with the final results. Therefore, the authors conclude that their approach is suitable for the treatment of type I and type II constricted ears.

  9. Cutibacterium acnes molecular typing: time to standardize the method.

    PubMed

    Dagnelie, M-A; Khammari, A; Dréno, B; Corvec, S

    2018-03-12

    The Gram-positive, anaerobic/aerotolerant bacterium Cutibacterium acnes is a commensal of healthy human skin; it is subdivided into six main phylogenetic groups or phylotypes: IA1, IA2, IB, IC, II and III. To decipher how far specific subgroups of C. acnes are involved in disease physiopathology, different molecular typing methods have been developed to identify these subgroups: i.e. phylotypes, clonal complexes, and types defined by single-locus sequence typing (SLST). However, as several molecular typing methods have been developed over the last decade, it has become a difficult task to compare the results from one article to another. Based on the scientific literature, the aim of this narrative review is to propose a standardized method to perform molecular typing of C. acnes, according to the degree of resolution needed (phylotypes, clonal complexes, or SLST types). We discuss the existing different typing methods from a critical point of view, emphasizing their advantages and drawbacks, and we identify the most frequently used methods. We propose a consensus algorithm according to the needed phylogeny resolution level. We first propose to use multiplex PCR for phylotype identification, MLST9 for clonal complex determination, and SLST for phylogeny investigation including numerous isolates. There is an obvious need to create a consensus about molecular typing methods for C. acnes. This standardization will facilitate the comparison of results between one article and another, and also the interpretation of clinical data. Copyright © 2018 European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

  10. Comparison of a newly developed binary typing with ribotyping and multilocus sequence typing methods for Clostridium difficile.

    PubMed

    Li, Zhirong; Liu, Xiaolei; Zhao, Jianhong; Xu, Kaiyue; Tian, Tiantian; Yang, Jing; Qiang, Cuixin; Shi, Dongyan; Wei, Honglian; Sun, Suju; Cui, Qingqing; Li, Ruxin; Niu, Yanan; Huang, Bixing

    2018-04-01

    Clostridium difficile is the causative pathogen for antibiotic-related nosocomial diarrhea. For epidemiological study and identification of virulent clones, a new binary typing method was developed for C. difficile in this study. The usefulness of this newly developed optimized 10-loci binary typing method was compared with two widely used methods ribotyping and multilocus sequence typing (MLST) in 189 C. difficile samples. The binary typing, ribotyping and MLST typed the samples into 53 binary types (BTs), 26 ribotypes (RTs), and 33 MLST sequence types (STs), respectively. The typing ability of the binary method was better than that of either ribotyping or MLST expressed in Simpson Index (SI) at 0.937, 0.892 and 0.859, respectively. The ease of testing, portability and cost-effectiveness of the new binary typing would make it a useful typing alternative for outbreak investigations within healthcare facilities and epidemiological research. Copyright © 2018 Elsevier B.V. All rights reserved.

  11. A Heuristic Fast Method to Solve the Nonlinear Schroedinger Equation in Fiber Bragg Gratings with Arbitrary Shape Input Pulse

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Emami, F.; Hatami, M.; Keshavarz, A. R.

    2009-08-13

    Using a combination of Runge-Kutta and Jacobi iterative method, we could solve the nonlinear Schroedinger equation describing the pulse propagation in FBGs. By decomposing the electric field to forward and backward components in fiber Bragg grating and utilizing the Fourier series analysis technique, the boundary value problem of a set of coupled equations governing the pulse propagation in FBG changes to an initial condition coupled equations which can be solved by simple Runge-Kutta method.

  12. Validation of the Davidson Trauma Scale in its original and a new shorter version in people exposed to the F-27 earthquake in Chile

    PubMed Central

    Leiva-Bianchi, Marcelo C.; Araneda, Andrea C.

    2013-01-01

    Background On February 27, 2010 (F-27), an earthquake and tsunami occurred having a significant impact on the mental health of the Chilean population, leading to an increase in cases of post-traumatic stress disorder (PTSD). Objectives Within this context, validated for the first time in Chile was the Davidson Trauma Scale (DTS) using three samples (each one consisting of 200 participants), two of them random from the Chilean population. Results Reliability analyses (i.e., α=0.933), concurrent validity (63% of the items are significantly correlated with the criteria variable “degree of damage to home”) and construct validity (i.e., CMIN = 3.754, RMSEA = 0.118, NFI = 0.808, CFI = 0.850 and PNFI = 0.689) indicate validity between regular and good for DTS. However, a new short version of the scale (DTS-SF) created using the items with heavier factor weights, presented better fits (CMIN = 2.170, RMSEA = 0.077, NFI = 0.935, CFI = 0.963, PNFI = 0.697). Discussion Finally, the usefulness of DTS and DTS-SF is discussed, the latter being briefer, valid and having better psychometric characteristics. PMID:23983920

  13. Teardrop and heart orbits of a swinging Atwood's machine

    NASA Astrophysics Data System (ADS)

    Tufillaro, Nicholas B.

    1994-03-01

    An exact solution is presented for a swinging Atwood's machine. This teardrop-heart orbit is constructed using Hamilton-Jacobi theory. The example nicely illustrates the utility of the Hamilton-Jacobi method for finding solutions to nonlinear mechanical systems when more elementary techniques fail.

  14. A new compound control method for sine-on-random mixed vibration test

    NASA Astrophysics Data System (ADS)

    Zhang, Buyun; Wang, Ruochen; Zeng, Falin

    2017-09-01

    Vibration environmental test (VET) is one of the important and effective methods to provide supports for the strength design, reliability and durability test of mechanical products. A new separation control strategy was proposed to apply in multiple-input multiple-output (MIMO) sine on random (SOR) mixed mode vibration test, which is the advanced and intensive test type of VET. As the key problem of the strategy, correlation integral method was applied to separate the mixed signals which included random and sinusoidal components. The feedback control formula of MIMO linear random vibration system was systematically deduced in frequency domain, and Jacobi control algorithm was proposed in view of the elements, such as self-spectrum, coherence, and phase of power spectral density (PSD) matrix. Based on the excessive correction of excitation in sine vibration test, compression factor was introduced to reduce the excitation correction, avoiding the destruction to vibration table or other devices. The two methods were synthesized to be applied in MIMO SOR vibration test system. In the final, verification test system with the vibration of a cantilever beam as the control object was established to verify the reliability and effectiveness of the methods proposed in the paper. The test results show that the exceeding values can be controlled in the tolerance range of references accurately, and the method can supply theory and application supports for mechanical engineering.

  15. High performance p-type thermoelectric materials and methods of preparation

    NASA Technical Reports Server (NTRS)

    Caillat, Thierry (Inventor); Borshchevsky, Alexander (Inventor); Fleurial, Jean-Pierre (Inventor)

    2005-01-01

    The present invention is embodied in high performance p-type thermoelectric materials having enhanced thermoelectric properties and the methods of preparing such materials. In one aspect of the invention, p-type semiconductors of formula Zn4-xAxSb3-yBy wherein 0?x?4, A is a transition metal, B is a pnicogen, and 0?y?3 are formed for use in manufacturing thermoelectric devices with substantially enhanced operating characteristics and improved efficiency. Two methods of preparing p-type Zn4Sb3 and related alloys of the present invention include a crystal growth method and a powder metallurgy method.

  16. Streptococcus group B typing: comparison of counter-immunoelectrophoresis with the precipitin method.

    PubMed

    Kubín, V; Jelínková, J; Franêk, J

    1977-07-01

    The method of counter-immunoelectrophoresis (CIE) was tested for its applicability to group B streptococcus typing. The results obtained were compared with the typing by the ring precipitin test. Identical antigens and identical hyperimmune typing serum batches had been used in both methods. A large majority of 75 freshly isolated strains were typed identically by both methods. Five strains with a weak antigenic outfit were untypable by the ring precipitin test but were typed by CIE owing to a higher sensitivity of CIE method. Two strains were typable by the precipitin test but not by CIE; an explanation for this phenomenon is lacking. The CIE method in group B typing is specific, rapid, highly sensitive and relatively simple. It requires strict maintenance of standard conditions. The method is economical with respect to manipulation and material, requires small amounts of diagnostic antisera. Potent antisera may be used diluted. Moreover, sera for CIE typing need not be absorbed to remove group B antibodies. CIE method is practicable for group B streptococcus typing, especially in laboratories carrying out routine large scale type identification.

  17. n-Type diamond and method for producing same

    DOEpatents

    Anderson, Richard J.

    2002-01-01

    A new n-type semiconducting diamond is disclosed, which is doped with n-type dopant atoms. Such diamond is advantageously formed by chemical vapor deposition from a source gas mixture comprising a carbon source compound for the diamond, and a volatile hot wire filament for the n-type impurity species, so that the n-type impurity atoms are doped in the diamond during its formation. A corresponding chemical vapor deposition method of forming the n-type semiconducting diamond is disclosed. The n-type semiconducting diamond of the invention may be usefully employed in the formation of diamond-based transistor devices comprising pn diamond junctions, and in other microelectronic device applications.

  18. Efficient solution of the simplified P N equations

    DOE PAGES

    Hamilton, Steven P.; Evans, Thomas M.

    2014-12-23

    We show new solver strategies for the multigroup SPN equations for nuclear reactor analysis. By forming the complete matrix over space, moments, and energy a robust set of solution strategies may be applied. Moreover, power iteration, shifted power iteration, Rayleigh quotient iteration, Arnoldi's method, and a generalized Davidson method, each using algebraic and physics-based multigrid preconditioners, have been compared on C5G7 MOX test problem as well as an operational PWR model. These results show that the most ecient approach is the generalized Davidson method, that is 30-40 times faster than traditional power iteration and 6-10 times faster than Arnoldi's method.

  19. A conjugate gradient method for solving the non-LTE line radiation transfer problem

    NASA Astrophysics Data System (ADS)

    Paletou, F.; Anterrieu, E.

    2009-12-01

    This study concerns the fast and accurate solution of the line radiation transfer problem, under non-LTE conditions. We propose and evaluate an alternative iterative scheme to the classical ALI-Jacobi method, and to the more recently proposed Gauss-Seidel and successive over-relaxation (GS/SOR) schemes. Our study is indeed based on applying a preconditioned bi-conjugate gradient method (BiCG-P). Standard tests, in 1D plane parallel geometry and in the frame of the two-level atom model with monochromatic scattering are discussed. Rates of convergence between the previously mentioned iterative schemes are compared, as are their respective timing properties. The smoothing capability of the BiCG-P method is also demonstrated.

  20. Fine typing of methicillin-resistant Staphylococcus aureus isolates using direct repeat unit and staphylococcal interspersed repeat unit typing methods.

    PubMed

    Ho, Cheng-Mao; Ho, Mao-Wang; Li, Chi-Yuan; Lu, Jang-Jih

    2015-08-01

    Methicillin-resistant Staphylococcus aureus (MRSA) typing is an important epidemiologic tool for monitoring trends and preventing outbreaks. However, the efficiency of various MRSA typing methods for each SCCmec MRSA isolate is rarely evaluated. A total of 157 MRSA isolates from four different regions in Taiwan were typed with five different molecular methods, including SCCmec typing, multilocus sequence typing (MLST), spa typing, mec-associated direct repeat unit (dru) copy number determination, and staphylococcal interspersed repeat unit (SIRU) profiling. There were four SCCmec types, eight MLST types, 15 spa types, 11 dru types, and 31 SIRU profiles. The most common type determined by each molecular typing method was SCCmec III (115 isolates, 73.2%), ST239 (99 isolates, 63.1%), t037 (107 isolates, 68.2%), 14 dru copies (76 isolates, 48.4%), and SIRU profile 3013722 (102 isolates, 65%), respectively. When using the combination of MLST, spa typing, and dru copy number, ST5-t002-4 (n = 8), ST239-t037-14 (n = 68), ST59-t437-9 (n = 9), and ST59-t437-11 (n = 6) were found to be the most common types of SCCmec types II (n = 9), III (n = 115), IV (n = 21), and VT (n = 11) isolates, respectively. SCCmec type III isolates were further classified into 11 dru types. Of the 21 SCCmec type IV isolates, 14 SIRU profiles were found. Seven SIRU patterns were observed in the 11 SCCmec type VT isolates. Different typing methods showed a similar Hunter-Gaston discrimination index among the 157 MRSA isolates. However, dru and SIRU typing methods had a better discriminatory power for SCCmec type III and SCCmec types IV and VT isolates, respectively, suggesting that dru and SIRU can be used to further type these isolates. Copyright © 2013. Published by Elsevier B.V.

  1. Discriminative power of Campylobacter phenotypic and genotypic typing methods.

    PubMed

    Duarte, Alexandra; Seliwiorstow, Tomasz; Miller, William G; De Zutter, Lieven; Uyttendaele, Mieke; Dierick, Katelijne; Botteldoorn, Nadine

    2016-06-01

    The aim of this study was to compare different typing methods, individually and combined, for use in the monitoring of Campylobacter in food. Campylobacter jejuni (n=94) and Campylobacter coli (n=52) isolated from different broiler meat carcasses were characterized using multilocus sequence typing (MLST), flagellin gene A restriction fragment length polymorphism typing (flaA-RFLP), antimicrobial resistance profiling (AMRp), the presence/absence of 5 putative virulence genes; and, exclusively for C. jejuni, the determination of lipooligosaccharide (LOS) class. Discriminatory power was calculated by the Simpson's index of diversity (SID) and the congruence was measured by the adjusted Rand index and adjusted Wallace coefficient. MLST was individually the most discriminative typing method for both C. jejuni (SID=0.981) and C. coli (SID=0.957). The most discriminative combination with a SID of 0.992 for both C. jejuni and C. coli was obtained by combining MLST with flaA-RFLP. The combination of MLST with flaA-RFLP is an easy and feasible typing method for short-term monitoring of Campylobacter in broiler meat carcass. Copyright © 2016 Elsevier B.V. All rights reserved.

  2. High performance P-type thermoelectric materials and methods of preparation

    NASA Technical Reports Server (NTRS)

    Caillat, Thierry (Inventor); Borshchevsky, Alexander (Inventor); Fleurial, Jean-Pierre (Inventor)

    2002-01-01

    The present invention is embodied in high performance p-type thermoelectric materials having enhanced thermoelectric properties and the methods of preparing such materials. In one aspect of the invention, p-type semiconductors of formula Zn.sub.4-x A.sub.x Sb.sub.3-y B.sub.y wherein 0.ltoreq.x.ltoreq.4, A is a transition metal, B is a pnicogen, and 0.ltoreq.y.ltoreq.3 are formed for use in manufacturing thermoelectric devices with substantially enhanced operating characteristics and improved efficiency. Two methods of preparing p-type Zn.sub.4 Sb.sub.3 and related alloys of the present invention include a crystal growth method and a powder metallurgy method.

  3. Equivalences of the multi-indexed orthogonal polynomials

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Odake, Satoru

    2014-01-15

    Multi-indexed orthogonal polynomials describe eigenfunctions of exactly solvable shape-invariant quantum mechanical systems in one dimension obtained by the method of virtual states deletion. Multi-indexed orthogonal polynomials are labeled by a set of degrees of polynomial parts of virtual state wavefunctions. For multi-indexed orthogonal polynomials of Laguerre, Jacobi, Wilson, and Askey-Wilson types, two different index sets may give equivalent multi-indexed orthogonal polynomials. We clarify these equivalences. Multi-indexed orthogonal polynomials with both type I and II indices are proportional to those of type I indices only (or type II indices only) with shifted parameters.

  4. Periodic three-body orbits with vanishing angular momentum in the Jacobi-Poincaré ‘strong’ potential

    NASA Astrophysics Data System (ADS)

    Dmitrašinović, V.; Petrović, Luka V.; Šuvakov, Milovan

    2017-10-01

    Moore (1993 Phys. Rev. Lett. 70 3675) and Montgomery (2005 Ergod. Theor. Dynam. Syst. 25 921-947) have argued that planar periodic orbits of three bodies moving in the Jacobi-Poincaré, or the ‘strong’ pairwise potential \\sumi>j\\frac{-1}{rij^2} , can have all possible topologies. Here we search systematically for such orbits with vanishing angular momentum and find 24 topologically distinct orbits, 22 of which are new, in a small section of the allowed phase space, with a tendency to overcrowd, due to overlapping initial conditions. The topologies of these 24 orbits belong to three algebraic sequences defined as functions of integer n=0, 1, 2, \\ldots . Each sequence extends to n \\to ∞ , but the separation of initial conditions for orbits with n ≥slant 10 becomes practically impossible with a numerical precision of 16 decimal places. Nevertheless, even with a precision of 16 decimals, it is clear that in each sequence both the orbit’s initial angle φn and its period T n approach finite values in the asymptotic limit (n \\to ∞ ). Two of three sequences are overlapping in the sense that their initial angles ϕ occupy the same segment on the circle and their asymptotic values φ∞ are (very) close to each other. The actions of these orbits rise linearly with the index n that describes the orbit’s topology, which is in agreement with the Newtonian case. We show that this behaviour is consistent with the assumption of analyticity of the action as a function of period.

  5. Mechanical treatment methods in the pinon-juniper type

    Treesearch

    Brent J. Racher

    2008-01-01

    (Please note, this is an abstract only) Mechanical treatments in the pinon-juniper type are driven by the objectives of the treatment. Objectives of restoring meadows or grassland from encroachment or returning to a savanna can require a different method of treatment than thinning pinon-juniper woodlands. Often these types of objectives are intermingled within a...

  6. Local Discontinuous Galerkin Methods for the Cahn-Hilliard Type Equations

    DTIC Science & Technology

    2007-01-01

    Kuramoto-Sivashinsky equations , the Ito-type coupled KdV equa- tions, the Kadomtsev - Petviashvili equation , and the Zakharov-Kuznetsov equation . A common...Local discontinuous Galerkin methods for the Cahn-Hilliard type equations Yinhua Xia∗, Yan Xu† and Chi-Wang Shu ‡ Abstract In this paper we develop...local discontinuous Galerkin (LDG) methods for the fourth-order nonlinear Cahn-Hilliard equation and system. The energy stability of the LDG methods is

  7. Complex-valued derivative propagation method with approximate Bohmian trajectories: Application to electronic nonadiabatic dynamics

    NASA Astrophysics Data System (ADS)

    Wang, Yu; Chou, Chia-Chun

    2018-05-01

    The coupled complex quantum Hamilton-Jacobi equations for electronic nonadiabatic transitions are approximately solved by propagating individual quantum trajectories in real space. Equations of motion are derived through use of the derivative propagation method for the complex actions and their spatial derivatives for wave packets moving on each of the coupled electronic potential surfaces. These equations for two surfaces are converted into the moving frame with the same grid point velocities. Excellent wave functions can be obtained by making use of the superposition principle even when nodes develop in wave packet scattering.

  8. 3D level set methods for evolving fronts on tetrahedral meshes with adaptive mesh refinement

    DOE PAGES

    Morgan, Nathaniel Ray; Waltz, Jacob I.

    2017-03-02

    The level set method is commonly used to model dynamically evolving fronts and interfaces. In this work, we present new methods for evolving fronts with a specified velocity field or in the surface normal direction on 3D unstructured tetrahedral meshes with adaptive mesh refinement (AMR). The level set field is located at the nodes of the tetrahedral cells and is evolved using new upwind discretizations of Hamilton–Jacobi equations combined with a Runge–Kutta method for temporal integration. The level set field is periodically reinitialized to a signed distance function using an iterative approach with a new upwind gradient. We discuss themore » details of these level set and reinitialization methods. Results from a range of numerical test problems are presented.« less

  9. Twostep-by-twostep PIRK-type PC methods with continuous output formulas

    NASA Astrophysics Data System (ADS)

    Cong, Nguyen Huu; Xuan, Le Ngoc

    2008-11-01

    This paper deals with parallel predictor-corrector (PC) iteration methods based on collocation Runge-Kutta (RK) corrector methods with continuous output formulas for solving nonstiff initial-value problems (IVPs) for systems of first-order differential equations. At nth step, the continuous output formulas are used not only for predicting the stage values in the PC iteration methods but also for calculating the step values at (n+2)th step. In this case, the integration processes can be proceeded twostep-by-twostep. The resulting twostep-by-twostep (TBT) parallel-iterated RK-type (PIRK-type) methods with continuous output formulas (twostep-by-twostep PIRKC methods or TBTPIRKC methods) give us a faster integration process. Fixed stepsize applications of these TBTPIRKC methods to a few widely-used test problems reveal that the new PC methods are much more efficient when compared with the well-known parallel-iterated RK methods (PIRK methods), parallel-iterated RK-type PC methods with continuous output formulas (PIRKC methods) and sequential explicit RK codes DOPRI5 and DOP853 available from the literature.

  10. Select-divide-and-conquer method for large-scale configuration interaction

    NASA Astrophysics Data System (ADS)

    Bunge, Carlos F.; Carbó-Dorca, Ramon

    2006-07-01

    A select-divide-and-conquer variational method to approximate configuration interaction (CI) is presented. Given an orthonormal set made up of occupied orbitals (Hartree-Fock or similar) and suitable correlation orbitals (natural or localized orbitals), a large N-electron target space S is split into subspaces S0,S1,S2,…,SR. S0, of dimension d0, contains all configurations K with attributes (energy contributions, etc.) above thresholds T0≡{T0egy,T0etc.}; the CI coefficients in S0 remain always free to vary. S1 accommodates Ks with attributes above T1⩽T0. An eigenproblem of dimension d0+d1 for S0+S1 is solved first, after which the last d1 rows and columns are contracted into a single row and column, thus freezing the last d1 CI coefficients hereinafter. The process is repeated with successive Sj(j ⩾2) chosen so that corresponding CI matrices fit random access memory (RAM). Davidson's eigensolver is used R times. The final energy eigenvalue (lowest or excited one) is always above the corresponding exact eigenvalue in S. Threshold values {Tj;j=0,1,2,…,R} regulate accuracy; for large-dimensional S, high accuracy requires S0+S1 to be solved outside RAM. From there on, however, usually a few Davidson iterations in RAM are needed for each step, so that Hamiltonian matrix-element evaluation becomes rate determining. One μhartree accuracy is achieved for an eigenproblem of order 24×106, involving 1.2×1012 nonzero matrix elements, and 8.4×109 Slater determinants.

  11. Discriminatory Indices of Typing Methods for Epidemiologic Analysis of Contemporary Staphylococcus aureus Strains.

    PubMed

    Rodriguez, Marcela; Hogan, Patrick G; Satola, Sarah W; Crispell, Emily; Wylie, Todd; Gao, Hongyu; Sodergren, Erica; Weinstock, George M; Burnham, Carey-Ann D; Fritz, Stephanie A

    2015-09-01

    Historically, a number of typing methods have been evaluated for Staphylococcus aureus strain characterization. The emergence of contemporary strains of community-associated S. aureus, and the ensuing epidemic with a predominant strain type (USA300), necessitates re-evaluation of the discriminatory power of these typing methods for discerning molecular epidemiology and transmission dynamics, essential to investigations of hospital and community outbreaks. We compared the discriminatory index of 5 typing methods for contemporary S. aureus strain characterization. Children presenting to St. Louis Children's Hospital and community pediatric practices in St. Louis, Missouri (MO), with community-associated S. aureus infections were enrolled. Repetitive sequence-based PCR (repPCR), pulsed-field gel electrophoresis (PFGE), multilocus sequence typing (MLST), staphylococcal protein A (spa), and staphylococcal cassette chromosome (SCC) mec typing were performed on 200 S. aureus isolates. The discriminatory index of each method was calculated using the standard formula for this metric, where a value of 1 is highly discriminatory and a value of 0 is not discriminatory. Overall, we identified 26 distinct strain types by repPCR, 17 strain types by PFGE, 30 strain types by MLST, 68 strain types by spa typing, and 5 strain types by SCCmec typing. RepPCR had the highest discriminatory index (D) of all methods (D = 0.88), followed by spa typing (D = 0.87), MLST (D = 0.84), PFGE (D = 0.76), and SCCmec typing (D = 0.60). The method with the highest D among MRSA isolates was repPCR (D = 0.64) followed by spa typing (D = 0.45) and MLST (D = 0.44). The method with the highest D among MSSA isolates was spa typing (D = 0.98), followed by MLST (D = 0.93), repPCR (D = 0.92), and PFGE (D = 0.89). Among isolates designated USA300 by PFGE, repPCR was most discriminatory, with 10 distinct strain types identified (D = 0.63). We identified 45

  12. Discriminatory Indices of Typing Methods for Epidemiologic Analysis of Contemporary Staphylococcus aureus Strains

    PubMed Central

    Rodriguez, Marcela; Hogan, Patrick G.; Satola, Sarah W.; Crispell, Emily; Wylie, Todd; Gao, Hongyu; Sodergren, Erica; Weinstock, George M.; Burnham, Carey-Ann D.; Fritz, Stephanie A.

    2015-01-01

    Abstract Historically, a number of typing methods have been evaluated for Staphylococcus aureus strain characterization. The emergence of contemporary strains of community-associated S. aureus, and the ensuing epidemic with a predominant strain type (USA300), necessitates re-evaluation of the discriminatory power of these typing methods for discerning molecular epidemiology and transmission dynamics, essential to investigations of hospital and community outbreaks. We compared the discriminatory index of 5 typing methods for contemporary S. aureus strain characterization. Children presenting to St. Louis Children's Hospital and community pediatric practices in St. Louis, Missouri (MO), with community-associated S. aureus infections were enrolled. Repetitive sequence-based PCR (repPCR), pulsed-field gel electrophoresis (PFGE), multilocus sequence typing (MLST), staphylococcal protein A (spa), and staphylococcal cassette chromosome (SCC) mec typing were performed on 200 S. aureus isolates. The discriminatory index of each method was calculated using the standard formula for this metric, where a value of 1 is highly discriminatory and a value of 0 is not discriminatory. Overall, we identified 26 distinct strain types by repPCR, 17 strain types by PFGE, 30 strain types by MLST, 68 strain types by spa typing, and 5 strain types by SCCmec typing. RepPCR had the highest discriminatory index (D) of all methods (D = 0.88), followed by spa typing (D = 0.87), MLST (D = 0.84), PFGE (D = 0.76), and SCCmec typing (D = 0.60). The method with the highest D among MRSA isolates was repPCR (D = 0.64) followed by spa typing (D = 0.45) and MLST (D = 0.44). The method with the highest D among MSSA isolates was spa typing (D = 0.98), followed by MLST (D = 0.93), repPCR (D = 0.92), and PFGE (D = 0.89). Among isolates designated USA300 by PFGE, repPCR was most discriminatory, with 10 distinct strain types identified (D = 0.63). We

  13. Low-lying excited states of model proteins: Performances of the CC2 method versus multireference methods

    NASA Astrophysics Data System (ADS)

    Ben Amor, Nadia; Hoyau, Sophie; Maynau, Daniel; Brenner, Valérie

    2018-05-01

    A benchmark set of relevant geometries of a model protein, the N-acetylphenylalanylamide, is presented to assess the validity of the approximate second-order coupled cluster (CC2) method in studying low-lying excited states of such bio-relevant systems. The studies comprise investigations of basis-set dependence as well as comparison with two multireference methods, the multistate complete active space 2nd order perturbation theory (MS-CASPT2) and the multireference difference dedicated configuration interaction (DDCI) methods. First of all, the applicability and the accuracy of the quasi-linear multireference difference dedicated configuration interaction method have been demonstrated on bio-relevant systems by comparison with the results obtained by the standard MS-CASPT2. Second, both the nature and excitation energy of the first low-lying excited state obtained at the CC2 level are very close to the Davidson corrected CAS+DDCI ones, the mean absolute deviation on the excitation energy being equal to 0.1 eV with a maximum of less than 0.2 eV. Finally, for the following low-lying excited states, if the nature is always well reproduced at the CC2 level, the differences on excitation energies become more important and can depend on the geometry.

  14. Low-lying excited states of model proteins: Performances of the CC2 method versus multireference methods.

    PubMed

    Ben Amor, Nadia; Hoyau, Sophie; Maynau, Daniel; Brenner, Valérie

    2018-05-14

    A benchmark set of relevant geometries of a model protein, the N-acetylphenylalanylamide, is presented to assess the validity of the approximate second-order coupled cluster (CC2) method in studying low-lying excited states of such bio-relevant systems. The studies comprise investigations of basis-set dependence as well as comparison with two multireference methods, the multistate complete active space 2nd order perturbation theory (MS-CASPT2) and the multireference difference dedicated configuration interaction (DDCI) methods. First of all, the applicability and the accuracy of the quasi-linear multireference difference dedicated configuration interaction method have been demonstrated on bio-relevant systems by comparison with the results obtained by the standard MS-CASPT2. Second, both the nature and excitation energy of the first low-lying excited state obtained at the CC2 level are very close to the Davidson corrected CAS+DDCI ones, the mean absolute deviation on the excitation energy being equal to 0.1 eV with a maximum of less than 0.2 eV. Finally, for the following low-lying excited states, if the nature is always well reproduced at the CC2 level, the differences on excitation energies become more important and can depend on the geometry.

  15. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vankerschaver, Joris; Liao, Cuicui; Leok, Melvin

    The main goal of this paper is to derive an alternative characterization of the multisymplectic form formula for classical field theories using the geometry of the space of boundary values. We review the concept of Type-I/II generating functionals defined on the space of boundary data of a Lagrangian field theory. On the Lagrangian side, we define an analogue of Jacobi's solution to the Hamilton–Jacobi equation for field theories, and we show that by taking variational derivatives of this functional, we obtain an isotropic submanifold of the space of Cauchy data, described by the so-called multisymplectic form formula. As an examplemore » of the latter, we show that Lorentz's reciprocity principle in electromagnetism is a particular instance of the multisymplectic form formula. We also define a Hamiltonian analogue of Jacobi's solution, and we show that this functional is a Type-II generating functional. We finish the paper by defining a similar framework of generating functions for discrete field theories, and we show that for the linear wave equation, we recover the multisymplectic conservation law of Bridges.« less

  16. Codoping method for the fabrication of low-resistivity wide band-gap semiconductors in p-type GaN, p-type AlN and n-type diamond: prediction versus experiment

    NASA Astrophysics Data System (ADS)

    Katayama-Yoshida, H.; Nishimatsu, T.; Yamamoto, T.; Orita, N.

    2001-10-01

    We review our new valence control method of a co-doping for the fabrication of low-resistivity p-type GaN, p-type AlN and n-type diamond. The co-doping method is proposed based upon ab initio electronic structure calculation in order to solve the uni-polarity and the compensation problems in the wide band-gap semiconductors. In the co-doping method, we dope both the acceptors and donors at the same time by forming the meta-stable acceptor-donor-acceptor complexes for the p-type or donor-acceptor-donor complexes for the n-type under thermal non-equilibrium crystal growth conditions. We propose the following co-doping method to fabricate the low-resistivity wide band-gap semiconductors; p-type GaN: [Si + 2 Mg (or Be)], [H + 2 Mg (or Be)], [O + 2 Mg (or Be)], p-type AlN: [O + 2 C] and n-type diamond: [B + 2 N], [H + S], [H + 2 P]. We compare our prediction of the co-doping method with the recent successful experiments to fabricate the low-resistivity p-type GaN, p-type AlN and n-type diamond. We show that the co-doping method is the efficient and universal doping method by which to avoid carrier compensation with an increase of the solubility of the dopant, to increase the activation rate by decreasing the ionization energy of acceptors and donors, and to increase the mobility of the carrier.

  17. Discriminatory Power and Reproducibility of Novel DNA Typing Methods for Mycobacterium tuberculosis Complex Strains

    PubMed Central

    Kremer, Kristin; Arnold, Catherine; Cataldi, Angel; Gutiérrez, M. Cristina; Haas, Walter H.; Panaiotov, Stefan; Skuce, Robin A.; Supply, Philip; van der Zanden, Adri G. M.; van Soolingen, Dick

    2005-01-01

    In recent years various novel DNA typing methods have been developed which are faster and easier to perform than the current internationally standardized IS6110 restriction fragment length polymorphism typing method. However, there has been no overview of the utility of these novel typing methods, and it is largely unknown how they compare to previously published methods. In this study, the discriminative power and reproducibility of nine recently described PCR-based typing methods for Mycobacterium tuberculosis were investigated using the strain collection of the interlaboratory study of Kremer et al. (J. Clin. Microbiol. 37:2607-2618, 1999). This strain collection contains 90 M. tuberculosis complex and 10 non-M. tuberculosis complex mycobacterial strains, as well as 31 duplicated DNA samples to assess reproducibility. The highest reproducibility was found with variable numbers of tandem repeat typing using mycobacterial interspersed repetitive units (MIRU VNTR) and fast ligation-mediated PCR (FLiP), followed by second-generation spoligotyping, ligation-mediated PCR (LM-PCR), VNTR typing using five repeat loci identified at the Queens University of Belfast (QUB VNTR), and the Amadio speciation PCR. Poor reproducibility was associated with fluorescent amplified fragment length polymorphism typing, which was performed in three different laboratories. The methods were ordered from highest discrimination to lowest by the Hunter-Gaston discriminative index as follows: QUB VNTR typing, MIRU VNTR typing, FLiP, LM-PCR, and spoligotyping. We conclude that both VNTR typing methods and FLiP typing are rapid, highly reliable, and discriminative epidemiological typing methods for M. tuberculosis and that VNTR typing is the epidemiological typing method of choice for the near future. PMID:16272496

  18. Solving the interval type-2 fuzzy polynomial equation using the ranking method

    NASA Astrophysics Data System (ADS)

    Rahman, Nurhakimah Ab.; Abdullah, Lazim

    2014-07-01

    Polynomial equations with trapezoidal and triangular fuzzy numbers have attracted some interest among researchers in mathematics, engineering and social sciences. There are some methods that have been developed in order to solve these equations. In this study we are interested in introducing the interval type-2 fuzzy polynomial equation and solving it using the ranking method of fuzzy numbers. The ranking method concept was firstly proposed to find real roots of fuzzy polynomial equation. Therefore, the ranking method is applied to find real roots of the interval type-2 fuzzy polynomial equation. We transform the interval type-2 fuzzy polynomial equation to a system of crisp interval type-2 fuzzy polynomial equation. This transformation is performed using the ranking method of fuzzy numbers based on three parameters, namely value, ambiguity and fuzziness. Finally, we illustrate our approach by numerical example.

  19. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gorbachev, D V; Ivanov, V I

    Gauss and Markov quadrature formulae with nodes at zeros of eigenfunctions of a Sturm-Liouville problem, which are exact for entire functions of exponential type, are established. They generalize quadrature formulae involving zeros of Bessel functions, which were first designed by Frappier and Olivier. Bessel quadratures correspond to the Fourier-Hankel integral transform. Some other examples, connected with the Jacobi integral transform, Fourier series in Jacobi orthogonal polynomials and the general Sturm-Liouville problem with regular weight are also given. Bibliography: 39 titles.

  20. A multi-domain spectral method for time-fractional differential equations

    NASA Astrophysics Data System (ADS)

    Chen, Feng; Xu, Qinwu; Hesthaven, Jan S.

    2015-07-01

    This paper proposes an approach for high-order time integration within a multi-domain setting for time-fractional differential equations. Since the kernel is singular or nearly singular, two main difficulties arise after the domain decomposition: how to properly account for the history/memory part and how to perform the integration accurately. To address these issues, we propose a novel hybrid approach for the numerical integration based on the combination of three-term-recurrence relations of Jacobi polynomials and high-order Gauss quadrature. The different approximations used in the hybrid approach are justified theoretically and through numerical examples. Based on this, we propose a new multi-domain spectral method for high-order accurate time integrations and study its stability properties by identifying the method as a generalized linear method. Numerical experiments confirm hp-convergence for both time-fractional differential equations and time-fractional partial differential equations.

  1. A Ratio Method for Fluorescence Spectral Deconvolution.

    DTIC Science & Technology

    1980-11-20

    Christian, Gary , Abstr. 178th Meeting, ACS 1979, Vol. 1, Anal. 59. 10. Shelly, D. C.; Ilger, W. A.; Fogarty, M. P.; Warner, I. M.; Altex Chromatogram 1979, 3...Warner, Isiah M., Appl. Spec. 1980 34, 438-445. 13. Warner, Isiah, M.; Callis, James B.; Davidson, Ernest R.; Christian, Gary D., Clin. Chem. (Winston...R. A. Osteryoung Dr. G. M. Hieftje Department of Chemistry Department of Chemistry State University of New York Indiana University at Buffalo

  2. Improved Filon-type asymptotic methods for highly oscillatory differential equations with multiple time scales

    NASA Astrophysics Data System (ADS)

    Wang, Bin; Wu, Xinyuan

    2014-11-01

    In this paper we consider multi-frequency highly oscillatory second-order differential equations x″ (t) + Mx (t) = f (t , x (t) ,x‧ (t)) where high-frequency oscillations are generated by the linear part Mx (t), and M is positive semi-definite (not necessarily nonsingular). It is known that Filon-type methods are effective approach to numerically solving highly oscillatory problems. Unfortunately, however, existing Filon-type asymptotic methods fail to apply to the highly oscillatory second-order differential equations when M is singular. We study and propose an efficient improvement on the existing Filon-type asymptotic methods, so that the improved Filon-type asymptotic methods can be able to numerically solving this class of multi-frequency highly oscillatory systems with a singular matrix M. The improved Filon-type asymptotic methods are designed by combining Filon-type methods with the asymptotic methods based on the variation-of-constants formula. We also present one efficient and practical improved Filon-type asymptotic method which can be performed at lower cost. Accompanying numerical results show the remarkable efficiency.

  3. Generalization of Jacobi's Decomposition Theorem to the Rotation and Translation of a Solid in a Fluid.

    NASA Astrophysics Data System (ADS)

    Chiang, Rong-Chang

    Jacobi found that the rotation of a symmetrical heavy top about a fixed point is composed of the two torque -free rotations of two triaxial bodies about their centers of mass. His discovery rests on the fact that the orthogonal matrix which represents the rotation of a symmetrical heavy top is decomposed into a product of two orthogonal matrices, each of which represents the torque-free rotations of two triaxial bodies. This theorem is generalized to the Kirchhoff's case of the rotation and translation of a symmetrical solid in a fluid. This theorem requires the explicit computation, by means of theta functions, of the nine direction cosines between the rotating body axes and the fixed space axes. The addition theorem of theta functions makes it possible to decompose the rotational matrix into a product of similar matrices. This basic idea of utilizing the addition theorem is simple but the carry-through of the computation is quite involved and the full proof turns out to be a lengthy process of computing rather long and complex expressions. For the translational motion we give a new treatment. The position of the center of mass as a function of the time is found by a direct evaluation of the elliptic integral by means of a new theta interpretation of Legendre's reduction formula of the elliptic integral. For the complete solution of the problem we have added further the study of the physical aspects of the motion. Based on a complete examination of the all possible manifolds of the steady helical cases it is possible to obtain a full qualitative description of the motion. Many numerical examples and graphs are given to illustrate the rotation and translation of the solid in a fluid.

  4. Automatic identification of bacterial types using statistical imaging methods

    NASA Astrophysics Data System (ADS)

    Trattner, Sigal; Greenspan, Hayit; Tepper, Gapi; Abboud, Shimon

    2003-05-01

    The objective of the current study is to develop an automatic tool to identify bacterial types using computer-vision and statistical modeling techniques. Bacteriophage (phage)-typing methods are used to identify and extract representative profiles of bacterial types, such as the Staphylococcus Aureus. Current systems rely on the subjective reading of plaque profiles by human expert. This process is time-consuming and prone to errors, especially as technology is enabling the increase in the number of phages used for typing. The statistical methodology presented in this work, provides for an automated, objective and robust analysis of visual data, along with the ability to cope with increasing data volumes.

  5. 75 FR 34524 - Decision That Certain Nonconforming Motor Vehicles Are Eligible for Importation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-17

    ... Harley Davidson FX, FL, XL and VR Series Motorcycles. Substantially Similar U.S. Certified Vehicles: 2009 Harley Davidson FX, FL, XL and VR Series Motorcycles. Notice of Petition Published at: 74 FR 51943... and VR Series Motorcycles. Substantially Similar U.S. Certified Vehicles: 2008 Harley Davidson FX, FL...

  6. 40 CFR 81.343 - Tennessee.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... X Coffee County X Crockett County X Cumberland County X Those portions of Davidson County within a... Clay County X Cocke County X Coffee County X Crockett County X Cumberland County X Davidson County X... County Claiborne County Clay County Cocke County Coffee County Crockett County Cumberland County Davidson...

  7. 40 CFR 81.343 - Tennessee.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... X Coffee County X Crockett County X Cumberland County X Those portions of Davidson County within a... Clay County X Cocke County X Coffee County X Crockett County X Cumberland County X Davidson County X... County Claiborne County Clay County Cocke County Coffee County Crockett County Cumberland County Davidson...

  8. Improvement of the Owner Distinction Method for Healing-Type Pet Robots

    NASA Astrophysics Data System (ADS)

    Nambo, Hidetaka; Kimura, Haruhiko; Hara, Mirai; Abe, Koji; Tajima, Takuya

    In order to decrease human stress, Animal Assisted Therapy which applies pets to heal humans is attracted. However, since animals are insanitary and unsafe, it is difficult to practically apply animal pets in hospitals. For the reason, on behalf of animal pets, pet robots have been attracted. Since pet robots would have no problems in sanitation and safety, they are able to be applied as a substitute for animal pets in the therapy. In our previous study where pet robots distinguish their owners like an animal pet, we used a puppet type pet robot which has pressure type touch sensors. However, the accuracy of our method was not sufficient to practical use. In this paper, we propose a method to improve the accuracy of the distinction. The proposed method can be applied for capacitive touch sensors such as installed in AIBO in addition to pressure type touch sensors. Besides, this paper shows performance of the proposed method from experimental results and confirms the proposed method has improved performance of the distinction in the conventional method.

  9. GEMPIC: geometric electromagnetic particle-in-cell methods

    NASA Astrophysics Data System (ADS)

    Kraus, Michael; Kormann, Katharina; Morrison, Philip J.; Sonnendrücker, Eric

    2017-08-01

    We present a novel framework for finite element particle-in-cell methods based on the discretization of the underlying Hamiltonian structure of the Vlasov-Maxwell system. We derive a semi-discrete Poisson bracket, which retains the defining properties of a bracket, anti-symmetry and the Jacobi identity, as well as conservation of its Casimir invariants, implying that the semi-discrete system is still a Hamiltonian system. In order to obtain a fully discrete Poisson integrator, the semi-discrete bracket is used in conjunction with Hamiltonian splitting methods for integration in time. Techniques from finite element exterior calculus ensure conservation of the divergence of the magnetic field and Gauss' law as well as stability of the field solver. The resulting methods are gauge invariant, feature exact charge conservation and show excellent long-time energy and momentum behaviour. Due to the generality of our framework, these conservation properties are guaranteed independently of a particular choice of the finite element basis, as long as the corresponding finite element spaces satisfy certain compatibility conditions.

  10. Integrable Rosochatius deformations of the restricted soliton flows

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhou Ruguang

    2007-10-15

    A method to construct integrable Rosochatius deformations of the restricted soliton flows in the setup of Lax formulation is presented. The integrable Rosochatius deformations of the restricted soliton flows such as the restricted Ablowitz-Kaup-Newell-Segur flow, the restricted Tu-Meng flow, the restricted Tu flow with Neumann-type constraints, and the restricted modified Korteweg-de Vries flow, together with their Lax representations, are presented. In addition, a Lax representation of the Jacobi-Rosochatius system is obtained.

  11. A Well-Tempered Hybrid Method for Solving Challenging Time-Dependent Density Functional Theory (TDDFT) Systems.

    PubMed

    Kasper, Joseph M; Williams-Young, David B; Vecharynski, Eugene; Yang, Chao; Li, Xiaosong

    2018-04-10

    The time-dependent Hartree-Fock (TDHF) and time-dependent density functional theory (TDDFT) equations allow one to probe electronic resonances of a system quickly and inexpensively. However, the iterative solution of the eigenvalue problem can be challenging or impossible to converge, using standard methods such as the Davidson algorithm for spectrally dense regions in the interior of the spectrum, as are common in X-ray absorption spectroscopy (XAS). More robust solvers, such as the generalized preconditioned locally harmonic residual (GPLHR) method, can alleviate this problem, but at the expense of higher average computational cost. A hybrid method is proposed which adapts to the problem in order to maximize computational performance while providing the superior convergence of GPLHR. In addition, a modification to the GPLHR algorithm is proposed to adaptively choose the shift parameter to enforce a convergence of states above a predefined energy threshold.

  12. Steady state numerical solutions for determining the location of MEMS on projectile

    NASA Astrophysics Data System (ADS)

    Abiprayu, K.; Abdigusna, M. F. F.; Gunawan, P. H.

    2018-03-01

    This paper is devoted to compare the numerical solutions for the steady and unsteady state heat distribution model on projectile. Here, the best location for installing of the MEMS on the projectile based on the surface temperature is investigated. Numerical iteration methods, Jacobi and Gauss-Seidel have been elaborated to solve the steady state heat distribution model on projectile. The results using Jacobi and Gauss-Seidel are shown identical but the discrepancy iteration cost for each methods is gained. Using Jacobi’s method, the iteration cost is 350 iterations. Meanwhile, using Gauss-Seidel 188 iterations are obtained, faster than the Jacobi’s method. The comparison of the simulation by steady state model and the unsteady state model by a reference is shown satisfying. Moreover, the best candidate for installing MEMS on projectile is observed at pointT(10, 0) which has the lowest temperature for the other points. The temperature using Jacobi and Gauss-Seidel for scenario 1 and 2 atT(10, 0) are 307 and 309 Kelvin respectively.

  13. An updated Lagrangian discontinuous Galerkin hydrodynamic method for gas dynamics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wu, Tong; Shashkov, Mikhail Jurievich; Morgan, Nathaniel Ray

    Here, we present a new Lagrangian discontinuous Galerkin (DG) hydrodynamic method for gas dynamics. The new method evolves conserved unknowns in the current configuration, which obviates the Jacobi matrix that maps the element in a reference coordinate system or the initial coordinate system to the current configuration. The density, momentum, and total energy (ρ, ρu, E) are approximated with conservative higher-order Taylor expansions over the element and are limited toward a piecewise constant field near discontinuities using a limiter. Two new limiting methods are presented for enforcing the bounds on the primitive variables of density, velocity, and specific internal energymore » (ρ, u, e). The nodal velocity, and the corresponding forces, are calculated by solving an approximate Riemann problem at the element nodes. An explicit second-order method is used to temporally advance the solution. This new Lagrangian DG hydrodynamic method conserves mass, momentum, and total energy. 1D Cartesian coordinates test problem results are presented to demonstrate the accuracy and convergence order of the new DG method with the new limiters.« less

  14. An updated Lagrangian discontinuous Galerkin hydrodynamic method for gas dynamics

    DOE PAGES

    Wu, Tong; Shashkov, Mikhail Jurievich; Morgan, Nathaniel Ray; ...

    2018-04-09

    Here, we present a new Lagrangian discontinuous Galerkin (DG) hydrodynamic method for gas dynamics. The new method evolves conserved unknowns in the current configuration, which obviates the Jacobi matrix that maps the element in a reference coordinate system or the initial coordinate system to the current configuration. The density, momentum, and total energy (ρ, ρu, E) are approximated with conservative higher-order Taylor expansions over the element and are limited toward a piecewise constant field near discontinuities using a limiter. Two new limiting methods are presented for enforcing the bounds on the primitive variables of density, velocity, and specific internal energymore » (ρ, u, e). The nodal velocity, and the corresponding forces, are calculated by solving an approximate Riemann problem at the element nodes. An explicit second-order method is used to temporally advance the solution. This new Lagrangian DG hydrodynamic method conserves mass, momentum, and total energy. 1D Cartesian coordinates test problem results are presented to demonstrate the accuracy and convergence order of the new DG method with the new limiters.« less

  15. Method for identifying type I diabetes mellitus in humans

    DOEpatents

    Metz, Thomas O [Kennewick, WA; Qian, Weijun [Richland, WA; Jacobs, Jon M [Pasco, WA; Smith, Richard D [Richland, WA

    2011-04-12

    A method and system for classifying subject populations utilizing predictive and diagnostic biomarkers for type I diabetes mellitus. The method including determining the levels of a variety of markers within the serum or plasma of a target organism and correlating this level to general populations as a screen for predisposition or progressive monitoring of disease presence or predisposition.

  16. A least-squares finite element method for 3D incompressible Navier-Stokes equations

    NASA Technical Reports Server (NTRS)

    Jiang, Bo-Nan; Lin, T. L.; Hou, Lin-Jun; Povinelli, Louis A.

    1993-01-01

    The least-squares finite element method (LSFEM) based on the velocity-pressure-vorticity formulation is applied to three-dimensional steady incompressible Navier-Stokes problems. This method can accommodate equal-order interpolations, and results in symmetric, positive definite algebraic system. An additional compatibility equation, i.e., the divergence of vorticity vector should be zero, is included to make the first-order system elliptic. The Newton's method is employed to linearize the partial differential equations, the LSFEM is used to obtain discretized equations, and the system of algebraic equations is solved using the Jacobi preconditioned conjugate gradient method which avoids formation of either element or global matrices (matrix-free) to achieve high efficiency. The flow in a half of 3D cubic cavity is calculated at Re = 100, 400, and 1,000 with 50 x 52 x 25 trilinear elements. The Taylor-Gortler-like vortices are observed at Re = 1,000.

  17. "All Things Flow."

    ERIC Educational Resources Information Center

    Mohan, John M.

    1999-01-01

    Presents a tribute to Dan Davidson, American Department of Foreign Language's (ADFL) 1997 honoree as an outstanding educator, focusing on Davidson's work to expand Russian studies nationwide and forge ties between U.S. Russianists and Russia itself over the past decades, beginning with the post-Sputnik era. Davidson was able to go beyond the Iron…

  18. Comparison results on preconditioned SOR-type iterative method for Z-matrices linear systems

    NASA Astrophysics Data System (ADS)

    Wang, Xue-Zhong; Huang, Ting-Zhu; Fu, Ying-Ding

    2007-09-01

    In this paper, we present some comparison theorems on preconditioned iterative method for solving Z-matrices linear systems, Comparison results show that the rate of convergence of the Gauss-Seidel-type method is faster than the rate of convergence of the SOR-type iterative method.

  19. SYBR Green Real-Time PCR Method To Detect Clostridium botulinum Type A▿

    PubMed Central

    Fenicia, Lucia; Anniballi, Fabrizio; De Medici, Dario; Delibato, Elisabetta; Aureli, Paolo

    2007-01-01

    Botulinum toxins (BoNTs) are classically produced by Clostridium botulinum but rarely also from neurotoxigenic strains of Clostridium baratii and Clostridium butyricum. BoNT type A (BoNT/A), BoNT/B, BoNT/E, and very rarely BoNT/F are mainly responsible for human botulism. Standard microbiological methods take into consideration only the detection of C. botulinum. The presumptive identification of the toxigenic strains together with the typing of BoNT has to be performed by mouse bioassay. The development of PCR-based methods for the detection and typing of BoNT-producing clostridia would be an ideal alternative to the mouse bioassay. The objective of this study was to develop a rapid and robust real-time PCR method for detecting C. botulinum type A. Four different techniques for the extraction and purification of DNA from cultured samples were initially compared. Of the techniques used, Chelex 100, DNeasy tissue kit, InstaGene matrix DNA, and boiling, the boiling technique was significantly less efficient than the other three. These did not give statistically different results, and Chelex 100 was chosen because it was less expensive than the others. In order to eliminate any false-negative results, an internal amplification control was synthesized and included in the amplification mixture according to ISO 22174. The specificity of the method was tested against 75 strains of C. botulinum type A, 4 strains of C. botulinum type Ab, and 101 nontarget strains. The detection limit of the reaction was less than 6 × 101 copies of C. botulinum type A DNA. The robustness of the method was confirmed using naturally contaminated stool specimens to evaluate the tolerance of inhibitor substances. SYBR green real-time PCR showed very high specificity for the detection of C. botulinum types A and Ab (inclusivity and exclusivity, 100%). PMID:17369349

  20. Various methods of determining the natural frequencies and damping of composite cantilever plates. 3. The Ritz method

    NASA Astrophysics Data System (ADS)

    Ekel'chik, V. S.; Ryabov, V. M.

    1997-03-01

    The Ritz method was used to determine the frequencies and forms of free vibrations of rectangular cantilever plates made of anisotropic laminated composites. Orthogonal Jacobi and Legendre polynomials were used as coordinate functions. The results of the calculations are in good agreement with the published experimental and calculated data of other authors for plates made of boron and carbon fiber reinforced plastics with different angles of reinforcement of unidirectional layers and different sequence of placing the layers, and also of isotropic plates. The dissipative characteristics in vibrations were determined on the basis of the concept of complex moduli. The solution of the frequency equation with complex coefficients yields a complex frequency; the loss factors are determined from the ratio of the imaginary component of the complex frequency to the real component. For plates of unidirectionally reinforced carbon fiber plastic with different relative length a detailed analysis of the influence of the angle of reinforcement on the interaction and frequency transformation and on the loss factor was carried out. The article shows that the loss factor of a plate depends substantially on the type of vibration mode: bending or torsional. It also examines the asymptotics of the loss factors of plates when their length is increased, and it notes that the binomial model of deformation leads to a noticeable error in the calculation of the loss factor of long plates when the angle of reinforcement lies in the range 20°<φ<70°.

  1. Problems of Mathematical Finance by Stochastic Control Methods

    NASA Astrophysics Data System (ADS)

    Stettner, Łukasz

    The purpose of this paper is to present main ideas of mathematics of finance using the stochastic control methods. There is an interplay between stochastic control and mathematics of finance. On the one hand stochastic control is a powerful tool to study financial problems. On the other hand financial applications have stimulated development in several research subareas of stochastic control in the last two decades. We start with pricing of financial derivatives and modeling of asset prices, studying the conditions for the absence of arbitrage. Then we consider pricing of defaultable contingent claims. Investments in bonds lead us to the term structure modeling problems. Special attention is devoted to historical static portfolio analysis called Markowitz theory. We also briefly sketch dynamic portfolio problems using viscosity solutions to Hamilton-Jacobi-Bellman equation, martingale-convex analysis method or stochastic maximum principle together with backward stochastic differential equation. Finally, long time portfolio analysis for both risk neutral and risk sensitive functionals is introduced.

  2. Solution of D dimensional Dirac equation for coulombic potential using NU method and its thermodynamics properties

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cari, C., E-mail: cari@staff.uns.ac.id; Suparmi, A., E-mail: soeparmi@staff.uns.ac.id; Yunianto, M., E-mail: muhtaryunianto@staff.uns.ac.id

    2016-02-08

    The analytical solution of Ddimensional Dirac equation for Coulombic potential is investigated using Nikiforov-Uvarov method. The D dimensional relativistic energy spectra are obtained from relativistic energy eigenvalue equation by using Mat Lab software.The corresponding D dimensional radial wave functions are formulated in the form of generalized Jacobi and Laguerre Polynomials. In the non-relativistic limit, the relativistic energy equation reduces to the non-relativistic energy which will be applied to determine some thermodynamical properties of the system. The thermodynamical properties of the system are expressed in terms of error function and imaginary error function.

  3. Analytical methods applied to diverse types of Brazilian propolis

    PubMed Central

    2011-01-01

    Propolis is a bee product, composed mainly of plant resins and beeswax, therefore its chemical composition varies due to the geographic and plant origins of these resins, as well as the species of bee. Brazil is an important supplier of propolis on the world market and, although green colored propolis from the southeast is the most known and studied, several other types of propolis from Apis mellifera and native stingless bees (also called cerumen) can be found. Propolis is usually consumed as an extract, so the type of solvent and extractive procedures employed further affect its composition. Methods used for the extraction; analysis the percentage of resins, wax and insoluble material in crude propolis; determination of phenolic, flavonoid, amino acid and heavy metal contents are reviewed herein. Different chromatographic methods applied to the separation, identification and quantification of Brazilian propolis components and their relative strengths are discussed; as well as direct insertion mass spectrometry fingerprinting. Propolis has been used as a popular remedy for several centuries for a wide array of ailments. Its antimicrobial properties, present in propolis from different origins, have been extensively studied. But, more recently, anti-parasitic, anti-viral/immune stimulating, healing, anti-tumor, anti-inflammatory, antioxidant and analgesic activities of diverse types of Brazilian propolis have been evaluated. The most common methods employed and overviews of their relative results are presented. PMID:21631940

  4. Stable Numerical Approach for Fractional Delay Differential Equations

    NASA Astrophysics Data System (ADS)

    Singh, Harendra; Pandey, Rajesh K.; Baleanu, D.

    2017-12-01

    In this paper, we present a new stable numerical approach based on the operational matrix of integration of Jacobi polynomials for solving fractional delay differential equations (FDDEs). The operational matrix approach converts the FDDE into a system of linear equations, and hence the numerical solution is obtained by solving the linear system. The error analysis of the proposed method is also established. Further, a comparative study of the approximate solutions is provided for the test examples of the FDDE by varying the values of the parameters in the Jacobi polynomials. As in special case, the Jacobi polynomials reduce to the well-known polynomials such as (1) Legendre polynomial, (2) Chebyshev polynomial of second kind, (3) Chebyshev polynomial of third and (4) Chebyshev polynomial of fourth kind respectively. Maximum absolute error and root mean square error are calculated for the illustrated examples and presented in form of tables for the comparison purpose. Numerical stability of the presented method with respect to all four kind of polynomials are discussed. Further, the obtained numerical results are compared with some known methods from the literature and it is observed that obtained results from the proposed method is better than these methods.

  5. Solutions of interval type-2 fuzzy polynomials using a new ranking method

    NASA Astrophysics Data System (ADS)

    Rahman, Nurhakimah Ab.; Abdullah, Lazim; Ghani, Ahmad Termimi Ab.; Ahmad, Noor'Ani

    2015-10-01

    A few years ago, a ranking method have been introduced in the fuzzy polynomial equations. Concept of the ranking method is proposed to find actual roots of fuzzy polynomials (if exists). Fuzzy polynomials are transformed to system of crisp polynomials, performed by using ranking method based on three parameters namely, Value, Ambiguity and Fuzziness. However, it was found that solutions based on these three parameters are quite inefficient to produce answers. Therefore in this study a new ranking method have been developed with the aim to overcome the inherent weakness. The new ranking method which have four parameters are then applied in the interval type-2 fuzzy polynomials, covering the interval type-2 of fuzzy polynomial equation, dual fuzzy polynomial equations and system of fuzzy polynomials. The efficiency of the new ranking method then numerically considered in the triangular fuzzy numbers and the trapezoidal fuzzy numbers. Finally, the approximate solutions produced from the numerical examples indicate that the new ranking method successfully produced actual roots for the interval type-2 fuzzy polynomials.

  6. Current Methods in the Molecular Typing of Mycobacterium tuberculosis and Other Mycobacteria

    PubMed Central

    van Ingen, Jakko; Dziadek, Jarosław; Mazur, Paweł K.; Bielecki, Jacek

    2014-01-01

    In the epidemiology of tuberculosis (TB) and nontuberculous mycobacterial (NTM) diseases, as in all infectious diseases, the key issue is to define the source of infection and to disclose its routes of transmission and dissemination in the environment. For this to be accomplished, the ability of discerning and tracking individual Mycobacterium strains is of critical importance. Molecular typing methods have greatly improved our understanding of the biology of mycobacteria and provide powerful tools to combat the diseases caused by these pathogens. The utility of various typing methods depends on the Mycobacterium species under investigation as well as on the research question. For tuberculosis, different methods have different roles in phylogenetic analyses and person-to-person transmission studies. In NTM diseases, most investigations involve the search for environmental sources or phylogenetic relationships. Here, too, the type of setting determines which methodology is most suitable. Within this review, we summarize currently available molecular methods for strain typing of M. tuberculosis and some NTM species, most commonly associated with human disease. For the various methods, technical practicalities as well as discriminatory power and accomplishments are reviewed. PMID:24527454

  7. Application of the Group Foliation Method to the Complex Monge-Ampère Equation

    NASA Astrophysics Data System (ADS)

    Nutku, Y.; Sheftel, M. B.

    2001-04-01

    We apply the method of group foliation to the complex Monge-Ampère equation ( CMA 2) to establish a regular framework for finding its non-invariant solutions. We employ an infinite symmetry subgroup of CMA 2 to produce a foliation of the solution space into orbits of solutions with respect to this group and a corresponding splitting of CMA 2 into an automorphic system and a resolvent system. We propose a new approach to group foliation which is based on the commutator algebra of operators of invariant differentiation. This algebra together with its Jacobi identities provides the commutator representation of the resolvent system.

  8. A Self-Directed Method for Cell-Type Identification and Separation of Gene Expression Microarrays

    PubMed Central

    Zuckerman, Neta S.; Noam, Yair; Goldsmith, Andrea J.; Lee, Peter P.

    2013-01-01

    Gene expression analysis is generally performed on heterogeneous tissue samples consisting of multiple cell types. Current methods developed to separate heterogeneous gene expression rely on prior knowledge of the cell-type composition and/or signatures - these are not available in most public datasets. We present a novel method to identify the cell-type composition, signatures and proportions per sample without need for a-priori information. The method was successfully tested on controlled and semi-controlled datasets and performed as accurately as current methods that do require additional information. As such, this method enables the analysis of cell-type specific gene expression using existing large pools of publically available microarray datasets. PMID:23990767

  9. A Method for Determining Job Types for Low Aptitude Airmen.

    ERIC Educational Resources Information Center

    Mayo, Clyde C.

    An opinion survey method for identifying low aptitude job types was developed and used in a study of 11 Air Force career ladders. Lists of low aptitude tasks were defined by technical advisers. These tasks were then rated on nine factors by Air Force instructors who also described low aptitude job types and gave their opinion concerning the…

  10. Well-conditioned fractional collocation methods using fractional Birkhoff interpolation basis

    NASA Astrophysics Data System (ADS)

    Jiao, Yujian; Wang, Li-Lian; Huang, Can

    2016-01-01

    The purpose of this paper is twofold. Firstly, we provide explicit and compact formulas for computing both Caputo and (modified) Riemann-Liouville (RL) fractional pseudospectral differentiation matrices (F-PSDMs) of any order at general Jacobi-Gauss-Lobatto (JGL) points. We show that in the Caputo case, it suffices to compute F-PSDM of order μ ∈ (0 , 1) to compute that of any order k + μ with integer k ≥ 0, while in the modified RL case, it is only necessary to evaluate a fractional integral matrix of order μ ∈ (0 , 1). Secondly, we introduce suitable fractional JGL Birkhoff interpolation problems leading to new interpolation polynomial basis functions with remarkable properties: (i) the matrix generated from the new basis yields the exact inverse of F-PSDM at "interior" JGL points; (ii) the matrix of the highest fractional derivative in a collocation scheme under the new basis is diagonal; and (iii) the resulted linear system is well-conditioned in the Caputo case, while in the modified RL case, the eigenvalues of the coefficient matrix are highly concentrated. In both cases, the linear systems of the collocation schemes using the new basis can be solved by an iterative solver within a few iterations. Notably, the inverse can be computed in a very stable manner, so this offers optimal preconditioners for usual fractional collocation methods for fractional differential equations (FDEs). It is also noteworthy that the choice of certain special JGL points with parameters related to the order of the equations can ease the implementation. We highlight that the use of the Bateman's fractional integral formulas and fast transforms between Jacobi polynomials with different parameters, is essential for our algorithm development.

  11. Quantifying the Performance of P-Type Transparent Conducting Oxides by Experimental Methods

    PubMed Central

    Fleischer, Karsten; Norton, Emma; Mullarkey, Daragh; Caffrey, David; Shvets, Igor V.

    2017-01-01

    Screening for potential new materials with experimental and theoretical methods has led to the discovery of many promising candidate materials for p-type transparent conducting oxides. It is difficult to reliably assess a good p-type transparent conducting oxide (TCO) from limited information available at an early experimental stage. In this paper we discuss the influence of sample thickness on simple transmission measurements and how the sample thickness can skew the commonly used figure of merit of TCOs and their estimated band gap. We discuss this using copper-deficient CuCrO2 as an example, as it was already shown to be a good p-type TCO grown at low temperatures. We outline a modified figure of merit reducing thickness-dependent errors, as well as how modern ab initio screening methods can be used to augment experimental methods to assess new materials for potential applications as p-type TCOs, p-channel transparent thin film transistors, and selective contacts in solar cells. PMID:28862695

  12. Motorcycles on the Move

    ERIC Educational Resources Information Center

    McIntosh, Phyllis

    2013-01-01

    Motorcycles are the subject of this feature article, which explores such topics as the history of motorcycles, types of motorcycles, special interest motorcycle clubs, motorcycle rallies, the Harley-Davidson company, and Rolling Thunder. A list of websites of interest and a glossary of "motorcycle jargon" are included.

  13. Typing methods for the plague pathogen, Yersinia pestis.

    PubMed

    Lindler, Luther E

    2009-01-01

    Phenotypic and genotypic methodologies have been used to differentiate the etiological agent of plague, Yersinia pestis. Historically, phenotypic methods were used to place isolates into one of three biovars based on nitrate reduction and glycerol fermentation. Classification of Y. pestis into genetic subtypes is problematic due to the relative monomorphic nature of the pathogen. Resolution into groups is dependent on the number and types of loci used in the analysis. The last 5-10 years of research and analysis in the field of Y. pestis genotyping have resulted in a recognition by Western scientists that two basic types of Y. pestis exist. One type, considered to be classic strains that are able to cause human plague transmitted by the normal flea vector, is termed epidemic strains. The other type does not typically cause human infections by normal routes of infection, but is virulent for rodents and is termed endemic strains. Previous classification schemes used outside the Western hemisphere referred to these latter strains as Pestoides varieties of Y. pestis. Recent molecular analysis has definitely shown that both endemic and epidemic strains arose independently from a common Yersinia pseudotuberculosis ancestor. Currently, 11 major groups of Y. pestis are defined globally.

  14. State transformations and Hamiltonian structures for optimal control in discrete systems

    NASA Astrophysics Data System (ADS)

    Sieniutycz, S.

    2006-04-01

    Preserving usual definition of Hamiltonian H as the scalar product of rates and generalized momenta we investigate two basic classes of discrete optimal control processes governed by the difference rather than differential equations for the state transformation. The first class, linear in the time interval θ, secures the constancy of optimal H and satisfies a discrete Hamilton-Jacobi equation. The second class, nonlinear in θ, does not assure the constancy of optimal H and satisfies only a relationship that may be regarded as an equation of Hamilton-Jacobi type. The basic question asked is if and when Hamilton's canonical structures emerge in optimal discrete systems. For a constrained discrete control, general optimization algorithms are derived that constitute powerful theoretical and computational tools when evaluating extremum properties of constrained physical systems. The mathematical basis is Bellman's method of dynamic programming (DP) and its extension in the form of the so-called Carathéodory-Boltyanski (CB) stage optimality criterion which allows a variation of the terminal state that is otherwise fixed in Bellman's method. For systems with unconstrained intervals of the holdup time θ two powerful optimization algorithms are obtained: an unconventional discrete algorithm with a constant H and its counterpart for models nonlinear in θ. We also present the time-interval-constrained extension of the second algorithm. The results are general; namely, one arrives at: discrete canonical equations of Hamilton, maximum principles, and (at the continuous limit of processes with free intervals of time) the classical Hamilton-Jacobi theory, along with basic results of variational calculus. A vast spectrum of applications and an example are briefly discussed with particular attention paid to models nonlinear in the time interval θ.

  15. 48 CFR 35.006 - Contracting methods and contract type.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... indicated a high degree of probability that development is feasible and (2) the Government has determined... SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 35.006 Contracting methods and..., performance objectives, and specifications for the work can be defined will largely determine the type of...

  16. Characterization of Water and CO2 Adsorption by Stores 3A Desiccant Samples Using Thermal Gravimetric Analysis and Fourier Transform Infrared Spectroscopy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    RIVERA, DION A.; ALAM, M. KATHLEEN; MARTIN, LAURA

    2003-02-01

    Two lots of manufactured Type 3a zeolite samples were compared by TGA/IR analysis. The first lot, obtained from Davidson Chemical, a commercial vendor, was characterized during the previous study cycle for its water and water-plus-CO{sub 2} uptake in order to determine whether CO{sub 2} uptake prevented water adsorption by the zeolite. It was determined that CO{sub 2} did not hamper water adsorption using the Davidson zeolite. CO{sub 2} was found on the zeolite surface at dewpoints below -40 C, however it was found to be reversibly adsorbed. During the course of the previous studies, chemical analyses revealed that the Davidsonmore » 3a zeolite contained calcium in significant quantities, along with the traditional counterions potassium and sodium. Chemical analysis of a Type 3a zeolite sample retrieved from Kansas City (heretofore referred to as the ''Stores 3a'' sample) indicated that the Stores sample was a more traditional Type 3a zeolite, containing no calcium. TGA/IR studies this year focused on obtaining CO{sub 2} and water absorbance data from the Stores 3a zeolite. Within the Stores 3a sample, CO{sub 2} was found to be reversibly absorbed within the sample, but only at and below -60 C with 5% CO{sub 2} loading. The amount of CO{sub 2} observed eluting from the Stores zeolite at this condition was similar to what was observed from the Davidson zeolite sample but with a greater uncertainty in the measured value. The results of the Stores 3a studies are summarized within this report.« less

  17. Clostridium difficile infection: Early history, diagnosis and molecular strain typing methods.

    PubMed

    Rodriguez, C; Van Broeck, J; Taminiau, B; Delmée, M; Daube, G

    2016-08-01

    Recognised as the leading cause of nosocomial antibiotic-associated diarrhoea, the incidence of Clostridium difficile infection (CDI) remains high despite efforts to improve prevention and reduce the spread of the bacterium in healthcare settings. In the last decade, many studies have focused on the epidemiology and rapid diagnosis of CDI. In addition, different typing methods have been developed for epidemiological studies. This review explores the history of C. difficile and the current scope of the infection. The variety of available laboratory tests for CDI diagnosis and strain typing methods are also examined. Copyright © 2016 Elsevier Ltd. All rights reserved.

  18. [A wavelet-transform-based method for the automatic detection of late-type stars].

    PubMed

    Liu, Zhong-tian; Zhao, Rrui-zhen; Zhao, Yong-heng; Wu, Fu-chao

    2005-07-01

    The LAMOST project, the world largest sky survey project, urgently needs an automatic late-type stars detection system. However, to our knowledge, no effective methods for automatic late-type stars detection have been reported in the literature up to now. The present study work is intended to explore possible ways to deal with this issue. Here, by "late-type stars" we mean those stars with strong molecule absorption bands, including oxygen-rich M, L and T type stars and carbon-rich C stars. Based on experimental results, the authors find that after a wavelet transform with 5 scales on the late-type stars spectra, their frequency spectrum of the transformed coefficient on the 5th scale consistently manifests a unimodal distribution, and the energy of frequency spectrum is largely concentrated on a small neighborhood centered around the unique peak. However, for the spectra of other celestial bodies, the corresponding frequency spectrum is of multimodal and the energy of frequency spectrum is dispersible. Based on such a finding, the authors presented a wavelet-transform-based automatic late-type stars detection method. The proposed method is shown by extensive experiments to be practical and of good robustness.

  19. Chosen interval methods for solving linear interval systems with special type of matrix

    NASA Astrophysics Data System (ADS)

    Szyszka, Barbara

    2013-10-01

    The paper is devoted to chosen direct interval methods for solving linear interval systems with special type of matrix. This kind of matrix: band matrix with a parameter, from finite difference problem is obtained. Such linear systems occur while solving one dimensional wave equation (Partial Differential Equations of hyperbolic type) by using the central difference interval method of the second order. Interval methods are constructed so as the errors of method are enclosed in obtained results, therefore presented linear interval systems contain elements that determining the errors of difference method. The chosen direct algorithms have been applied for solving linear systems because they have no errors of method. All calculations were performed in floating-point interval arithmetic.

  20. Inequity of Human Services: The Rural Tennessee Dilemma.

    ERIC Educational Resources Information Center

    Tennessee State Univ., Nashville.

    Davidson, Williamson, Rutherford, and Cheatham counties of Tennessee were the setting for a study that sought to determine the types of health and social services provided to residents of rural areas and to assess the present status of the service delivery system. Interviews with both agency representatives and randomly selected household…

  1. [Detection of constitutional types of EEG using the orthogonal decomposition method].

    PubMed

    Kuznetsova, S M; Kudritskaia, O V

    1987-01-01

    The authors present an algorithm of investigation into the processes of brain bioelectrical activity with the help of an orthogonal decomposition device intended for the identification of constitutional types of EEGs. The method has helped to effectively solve the task of the diagnosis of constitutional types of EEGs, which are determined by a variable degree of hereditary predisposition for longevity or cerebral stroke.

  2. Development of an ELA-DRA gene typing method based on pyrosequencing technology.

    PubMed

    Díaz, S; Echeverría, M G; It, V; Posik, D M; Rogberg-Muñoz, A; Pena, N L; Peral-García, P; Vega-Pla, J L; Giovambattista, G

    2008-11-01

    The polymorphism of equine lymphocyte antigen (ELA) class II DRA gene had been detected by polymerase chain reaction-single-strand conformational polymorphism (PCR-SSCP) and reference strand-mediated conformation analysis. These methodologies allowed to identify 11 ELA-DRA exon 2 sequences, three of which are widely distributed among domestic horse breeds. Herein, we describe the development of a pyrosequencing-based method applicable to ELA-DRA typing, by screening samples from eight different horse breeds previously typed by PCR-SSCP. This sequence-based method would be useful in high-throughput genotyping of major histocompatibility complex genes in horses and other animal species, making this system interesting as a rapid screening method for animal genotyping of immune-related genes.

  3. Molecular typing of Legionella pneumophila from air-conditioning cooling waters using mip gene, SBT, and FAFLP methods.

    PubMed

    Gong, Xiangli; Li, Juntao; Zhang, Ying; Hou, Shuiping; Qu, Pinghua; Yang, Zhicong; Chen, Shouyi

    2017-08-01

    Legionella spp. are important waterborne pathogens. Molecular typing has become an important method for outbreaks investigations and source tracking of Legionnaires. In a survey program conducted by the Guangzhou Center for Disease Control and Prevention, multiple serotypes Legionella pneumophila (L. pneumophila) were isolated from waters in air-conditioning cooling towers in urban Guangzhou region, China between 2008 and 2011. Three genotyping methods, mip (macrophage infectivity potentiator) genotyping, SBT (sequence-based typing), and FAFLP (fluorescent amplified fragment length polymorphism analysis) were used to type these waterborne L. pneumophila isolates. The three methods were capable of typing all the 134 isolates and a reference strain of L. pneumophila (ATCC33153), with discriminatory indices of 0.7034, 0.9218, and 0.9376, for the mip, SBT, and FAFLP methods respectively. Among the 9 serotypes of the 134 isolates, 10, 50, and 34 molecular types were detected by the mip, SBT, and FAFLP methods respectively. The mip genotyping and SBT typing are more feasible for inter-laboratory results sharing and comparison of different types of L. pneumophila. The SBT and FAFLP typing methods were rapid with higher discriminatory abilities. Combinations of two or more of the typing methods enables more accurate typing of Legionella isolates for outbreak investigations and source tracking of Legionnaires. Copyright © 2017 Elsevier B.V. All rights reserved.

  4. Method of mechanical quadratures for solving singular integral equations of various types

    NASA Astrophysics Data System (ADS)

    Sahakyan, A. V.; Amirjanyan, H. A.

    2018-04-01

    The method of mechanical quadratures is proposed as a common approach intended for solving the integral equations defined on finite intervals and containing Cauchy-type singular integrals. This method can be used to solve singular integral equations of the first and second kind, equations with generalized kernel, weakly singular equations, and integro-differential equations. The quadrature rules for several different integrals represented through the same coefficients are presented. This allows one to reduce the integral equations containing integrals of different types to a system of linear algebraic equations.

  5. Gauss-Seidel and Successive Overrelaxation Methods for Radiative Transfer with Partial Frequency Redistribution

    NASA Astrophysics Data System (ADS)

    Sampoorna, M.; Trujillo Bueno, J.

    2010-04-01

    The linearly polarized solar limb spectrum that is produced by scattering processes contains a wealth of information on the physical conditions and magnetic fields of the solar outer atmosphere, but the modeling of many of its strongest spectral lines requires solving an involved non-local thermodynamic equilibrium radiative transfer problem accounting for partial redistribution (PRD) effects. Fast radiative transfer methods for the numerical solution of PRD problems are also needed for a proper treatment of hydrogen lines when aiming at realistic time-dependent magnetohydrodynamic simulations of the solar chromosphere. Here we show how the two-level atom PRD problem with and without polarization can be solved accurately and efficiently via the application of highly convergent iterative schemes based on the Gauss-Seidel and successive overrelaxation (SOR) radiative transfer methods that had been previously developed for the complete redistribution case. Of particular interest is the Symmetric SOR method, which allows us to reach the fully converged solution with an order of magnitude of improvement in the total computational time with respect to the Jacobi-based local accelerated lambda iteration method.

  6. Efficient block preconditioned eigensolvers for linear response time-dependent density functional theory

    NASA Astrophysics Data System (ADS)

    Vecharynski, Eugene; Brabec, Jiri; Shao, Meiyue; Govind, Niranjan; Yang, Chao

    2017-12-01

    We present two efficient iterative algorithms for solving the linear response eigenvalue problem arising from the time dependent density functional theory. Although the matrix to be diagonalized is nonsymmetric, it has a special structure that can be exploited to save both memory and floating point operations. In particular, the nonsymmetric eigenvalue problem can be transformed into an eigenvalue problem that involves the product of two matrices M and K. We show that, because MK is self-adjoint with respect to the inner product induced by the matrix K, this product eigenvalue problem can be solved efficiently by a modified Davidson algorithm and a modified locally optimal block preconditioned conjugate gradient (LOBPCG) algorithm that make use of the K-inner product. The solution of the product eigenvalue problem yields one component of the eigenvector associated with the original eigenvalue problem. We show that the other component of the eigenvector can be easily recovered in an inexpensive postprocessing procedure. As a result, the algorithms we present here become more efficient than existing methods that try to approximate both components of the eigenvectors simultaneously. In particular, our numerical experiments demonstrate that the new algorithms presented here consistently outperform the existing state-of-the-art Davidson type solvers by a factor of two in both solution time and storage.

  7. From Lyme Disease to Art and Advocacy | NIH MedlinePlus the Magazine

    MedlinePlus

    ... Tick Bites Follow us From Lyme Disease to Art and Advocacy Bruce Davidson always enjoyed the outdoors. ... his recovery, Davidson has become "hyper-focused" on art and uses these talents to help others. "I ...

  8. Sociodemographic factors and health conditions associated with the resilience of people with chronic diseases: a cross sectional study 1

    PubMed Central

    Böell, Julia Estela Willrich; da Silva, Denise Maria Guerreiro Vieira; Hegadoren, Kathleen Mary

    2016-01-01

    ABSTRACT Objective: to investigate the association between resilience and sociodemographic variables and the health of people with chronic kidney disease and / or type 2 diabetes mellitus. Method: a cross-sectional observational study performed with 603 people with chronic kidney disease and / or type 2 diabetes mellitus. A tool to collect socio-demographic and health data and the Resilience Scale developed by Connor and Davidson were applied. A descriptive and multivariate analysis was performed. Results: the study participants had on average 61 years old (SD= 13.2), with a stable union (52.24%), religion (96.7%), retired (49.09%), with primary education (65%) and income up to three minimum wages. Participants with kidney disease showed less resilience than people with diabetes. Conclusion: the type of chronic illness, disease duration, body mass index and religious beliefs influenced the resilience of the study participants. PMID:27598377

  9. On optimal improvements of classical iterative schemes for Z-matrices

    NASA Astrophysics Data System (ADS)

    Noutsos, D.; Tzoumas, M.

    2006-04-01

    Many researchers have considered preconditioners, applied to linear systems, whose matrix coefficient is a Z- or an M-matrix, that make the associated Jacobi and Gauss-Seidel methods converge asymptotically faster than the unpreconditioned ones. Such preconditioners are chosen so that they eliminate the off-diagonal elements of the same column or the elements of the first upper diagonal [Milaszewicz, LAA 93 (1987) 161-170], Gunawardena et al. [LAA 154-156 (1991) 123-143]. In this work we generalize the previous preconditioners to obtain optimal methods. "Good" Jacobi and Gauss-Seidel algorithms are given and preconditioners, that eliminate more than one entry per row, are also proposed and analyzed. Moreover, the behavior of the above preconditioners to the Krylov subspace methods is studied.

  10. Prototyping method for Bragg-type atom interferometers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Benton, Brandon; Krygier, Michael; Heward, Jeffrey

    2011-10-15

    We present a method for rapid modeling of new Bragg ultracold atom-interferometer (AI) designs useful for assessing the performance of such interferometers. The method simulates the overall effect on the condensate wave function in a given AI design using two separate elements. These are (1) modeling the effect of a Bragg pulse on the wave function and (2) approximating the evolution of the wave function during the intervals between the pulses. The actual sequence of these pulses and intervals is then followed to determine the approximate final wave function from which the interference pattern can be calculated. The exact evolutionmore » between pulses is assumed to be governed by the Gross-Pitaevskii (GP) equation whose solution is approximated using a Lagrangian variational method to facilitate rapid estimation of performance. The method presented here is an extension of an earlier one that was used to analyze the results of an experiment [J. E. Simsarian et al., Phys. Rev. Lett. 85, 2040 (2000)], where the phase of a Bose-Einstein condensate was measured using a Mach-Zehnder-type Bragg AI. We have developed both 1D and 3D versions of this method and we have determined their validity by comparing their predicted interference patterns with those obtained by numerical integration of the 1D GP equation and with the results of the above experiment. We find excellent agreement between the 1D interference patterns predicted by this method and those found by the GP equation. We show that we can reproduce all of the results of that experiment without recourse to an ad hoc velocity-kick correction needed by the earlier method, including some experimental results that the earlier model did not predict. We also found that this method provides estimates of 1D interference patterns at least four orders-of-magnitude faster than direct numerical solution of the 1D GP equation.« less

  11. Two sympatric types of Plasmodium ovale and discrimination by molecular methods.

    PubMed

    Zaw, Myo Thura; Lin, Zaw

    2017-10-01

    Plasmodium ovale is widely distributed in tropical countries, whereas it has not been reported in the Americas. It is not a problem globally because it is rarely detected by microscopy owing to low parasite density, which is a feature of clinical ovale malaria. P.o. curtisi and P.o. wallikeri are widespread in both Africa and Asia, and were known to be sympatric in many African countries and in southeast Asian countries. Small subunit ribosomal RNA (SSUrRNA) gene, cytochrome b (cytb) gene, and merozoite surface protein-1 (msp-1) gene were initially studied for molecular discrimination of P.o. curtisi and P.o. wallikeri using polymerase chain reaction (PCR) and DNA sequencing. DNA sequences of other genes from P. ovale in Southeast Asia and the southwestern Pacific regions were also targeted to differentiate the two sympatric types. In terms of clinical manifestations, P.o. wallikeri tended to produce higher parasitemia levels and more severe symptoms. To date, there have been a few studies that used the quantitative PCR method for discrimination of the two distinct P. ovale types. Conventional PCR with consequent DNA sequencing is the common method used to differentiate these two types. It is necessary to identify these two types because relapse periodicity, drug susceptibility, and mosquito species preference need to be studied to reduce ovale malaria. In this article, an easier method of molecular-level discrimination of P.o. curtisi and P.o. wallikeri is proposed. Copyright © 2016. Published by Elsevier B.V.

  12. Normative data and psychometric properties of the Connor-Davidson Resilience Scale (CD-RISC) and the abbreviated version (CD-RISC2) among the general population in Hong Kong.

    PubMed

    Ni, Michael Y; Li, Tom K; Yu, Nancy X; Pang, Herbert; Chan, Brandford H Y; Leung, Gabriel M; Stewart, Sunita M

    2016-01-01

    To examine whether the two-item version (CD-RISC2) of the Connor-Davidson Resilience Scale (CD-RISC) has adequate internal consistency and construct validity, as well as significant correlation with the full scale, and to provide normative data for the CD-RISC and the CD-RISC2 in a Chinese general population in Hong Kong. In total, 10,997 randomly selected participants aged ≥20 years completed the Chinese version of the CD-RISC (including the 2 items of the CD-RISC2), the Patient Health Questionnaire, Family Harmony Scale, Family APGAR, and CAGE Questionnaire. Internal consistency and convergent and discriminant validity of the CD-RISC and CD-RISC2 were assessed. Cronbach's α for CD-RISC and CD-RISC2 was 0.97 and 0.79, respectively. CD-RISC2 was associated with the 25-item version of the CD-RISC (r = 0.88), depressive symptoms (r s = -0.18), family harmony (r = 0.20), family functioning (r = 0.27) and was not associated with alcohol consumption (r = 0.05). The mean score for the CD-RISC and CD-RISC2 was 59.99 (SD = 13.92) and 5.03 (SD = 1.37), respectively. Men, younger individuals, and those with higher education or higher household income reported higher resilience levels. The Chinese version of the CD-RISC2 was demonstrated to be a reliable and valid measure in assessing resilience among the general population in Hong Kong.

  13. Comparison effectiveness of cooperative learning type STAD with cooperative learning type TPS in terms of mathematical method of Junior High School students

    NASA Astrophysics Data System (ADS)

    Wahyuni, A.

    2018-05-01

    This research is aimed to find out whether the model of cooperative learning type Student Team Achievement Division (STAD) is more effective than cooperative learning type Think-Pair-Share in SMP Negeri 7 Yogyakarta. This research was a quasi-experimental research, using two experimental groups. The population of research was all students of 7thclass in SMP Negeri 7 Yogyakarta that consists of 5 Classes. From the population were taken 2 classes randomly which used as sample. The instrument to collect data was a description test. Measurement of instrument validity use content validity and construct validity, while measuring instrument reliability use Cronbach Alpha formula. To investigate the effectiveness of cooperative learning type STAD and cooperative learning type TPS on the aspect of student’s mathematical method, the datas were analyzed by one sample test. Comparing the effectiveness of cooperative learning type STAD and TPS in terms of mathematical communication skills by using t-test. Normality test was not conducted because the sample of research more than 30 students, while homogeneity tested by using Kolmogorov Smirnov test. The analysis was performed at 5% confidence level.The results show as follows : 1) The model of cooperative learning type STAD and TPS are effective in terms of mathematical method of junior high school students. 2). STAD type cooperative learning model is more effective than TPS type cooperative learning model in terms of mathematical methods of junior high school students.

  14. Exact traveling-wave and spatiotemporal soliton solutions to the generalized (3+1)-dimensional Schrödinger equation with polynomial nonlinearity of arbitrary order.

    PubMed

    Petrović, Nikola Z; Belić, Milivoj; Zhong, Wei-Ping

    2011-02-01

    We obtain exact traveling wave and spatiotemporal soliton solutions to the generalized (3+1)-dimensional nonlinear Schrödinger equation with variable coefficients and polynomial Kerr nonlinearity of an arbitrarily high order. Exact solutions, given in terms of Jacobi elliptic functions, are presented for the special cases of cubic-quintic and septic models. We demonstrate that the widely used method for finding exact solutions in terms of Jacobi elliptic functions is not applicable to the nonlinear Schrödinger equation with saturable nonlinearity. ©2011 American Physical Society

  15. Taxonomic changes in the genus Diabrotica Chevrolat (Coleoptera: Chrysomelidae: Galerucinae): results of a synopsis of North and Central America Diabrotica species

    USDA-ARS?s Scientific Manuscript database

    The following new synonyms in Diabrotica Chevrolat are proposed: D. flaviventris Jacoby 1887 = D. tibialis Jacoby 1887 = D. adelpha Harold 1875; D. peckii Bowditch 1911 = D. bioculata Bowditch 1911; D. circulata Harold 1875 = D. nummularis Harold 1877; D. linensis Bechyné 1956 = D. trifurcata Jacoby...

  16. The Movable Type Method Applied to Protein-Ligand Binding.

    PubMed

    Zheng, Zheng; Ucisik, Melek N; Merz, Kenneth M

    2013-12-10

    Accurately computing the free energy for biological processes like protein folding or protein-ligand association remains a challenging problem. Both describing the complex intermolecular forces involved and sampling the requisite configuration space make understanding these processes innately difficult. Herein, we address the sampling problem using a novel methodology we term "movable type". Conceptually it can be understood by analogy with the evolution of printing and, hence, the name movable type. For example, a common approach to the study of protein-ligand complexation involves taking a database of intact drug-like molecules and exhaustively docking them into a binding pocket. This is reminiscent of early woodblock printing where each page had to be laboriously created prior to printing a book. However, printing evolved to an approach where a database of symbols (letters, numerals, etc.) was created and then assembled using a movable type system, which allowed for the creation of all possible combinations of symbols on a given page, thereby, revolutionizing the dissemination of knowledge. Our movable type (MT) method involves the identification of all atom pairs seen in protein-ligand complexes and then creating two databases: one with their associated pairwise distant dependent energies and another associated with the probability of how these pairs can combine in terms of bonds, angles, dihedrals and non-bonded interactions. Combining these two databases coupled with the principles of statistical mechanics allows us to accurately estimate binding free energies as well as the pose of a ligand in a receptor. This method, by its mathematical construction, samples all of configuration space of a selected region (the protein active site here) in one shot without resorting to brute force sampling schemes involving Monte Carlo, genetic algorithms or molecular dynamics simulations making the methodology extremely efficient. Importantly, this method explores the free

  17. An Improved MLVF Method and Its Comparison with Traditional MLVF, spa Typing, MLST/SCCmec and PFGE for the Typing of Methicillin-Resistant Staphylococcus aureus

    PubMed Central

    Du, Xue-Fei; Xiao, Meng; Liang, Hong-Yan; Sun, Zhe; Jiang, Yue-Hong; Chen, Guo-Yu; Meng, Xiao-Yu; Zou, Gui-Ling; Zhang, Li; Liu, Ya-Li; Zhang, Hui; Sun, Hong-Li; Jiang, Xiao-Feng; Xu, Ying-Chun

    2014-01-01

    Methicillin-resistant Staphylococcus aureus (MRSA) has become an important nosocomial pathogen, causing considerable morbidity and mortality. During the last 20 years, a variety of genotyping methods have been introduced for screening the prevalence of MRSA. In this study, we developed and evaluated an improved approach capillary gel electrophoresis based multilocus variable-number tandem-repeat fingerprinting (CGE/MLVF) for rapid MRSA typing. A total of 42 well-characterized strains and 116 non-repetitive clinical MRSA isolates collected from six hospitals in northeast China between 2009 and 2010 were tested. The results obtained by CGE/MLVF against clinical isolates were compared with traditional MLVF, spa typing, Multilocus sequence typing/staphylococcal cassette chromosome mec (MLST/SCCmec) and pulse field gel electrophoresis (PFGE). The discriminatory power estimated by Simpson’s index of diversity was 0.855 (28 types), 0.855 (28 patterns), 0.623 (11 types), 0.517 (8 types) and 0.854 (28 patterns) for CGE/MLVF, traditional MLVF, spa typing, MLST/SCCmec and PFGE, respectively. All methods tested showed a satisfied concordance in clonal complex level calculated by adjusted Rand’s coefficient. CGE/MLVF showed better reproducibility and accuracy than traditional MLVF and PFGE methods. In addition, the CGE/MLVF has potential to produce portable results. In conclusion, CGE/MLVF is a rapid and easy to use MRSA typing method with lower cost, good reproducibility and high discriminatory power for monitoring the outbreak and clonal spread of MRSA isolates. PMID:24406728

  18. Numerical Evaluation of P-Multigrid Method for the Solution of Discontinuous Galerkin Discretizations of Diffusive Equations

    NASA Technical Reports Server (NTRS)

    Atkins, H. L.; Helenbrook, B. T.

    2005-01-01

    This paper describes numerical experiments with P-multigrid to corroborate analysis, validate the present implementation, and to examine issues that arise in the implementations of the various combinations of relaxation schemes, discretizations and P-multigrid methods. The two approaches to implement P-multigrid presented here are equivalent for most high-order discretization methods such as spectral element, SUPG, and discontinuous Galerkin applied to advection; however it is discovered that the approach that mimics the common geometric multigrid implementation is less robust, and frequently unstable when applied to discontinuous Galerkin discretizations of di usion. Gauss-Seidel relaxation converges 40% faster than block Jacobi, as predicted by analysis; however, the implementation of Gauss-Seidel is considerably more expensive that one would expect because gradients in most neighboring elements must be updated. A compromise quasi Gauss-Seidel relaxation method that evaluates the gradient in each element twice per iteration converges at rates similar to those predicted for true Gauss-Seidel.

  19. Comparison and Evaluation of the Molecular Typing Methods for Toxigenic Vibrio cholerae in Southwest China.

    PubMed

    Liao, Feng; Mo, Zhishuo; Chen, Meiling; Pang, Bo; Fu, Xiaoqing; Xu, Wen; Jing, Huaiqi; Kan, Biao; Gu, Wenpeng

    2018-01-01

    Vibrio cholerae O1 strains taken from the repository of Yunnan province, southwest China, were abundant and special. We selected 70 typical toxigenic V. cholerae (69 O1 and one O139 serogroup strains) isolated from Yunnan province, performed the pulsed field gel electrophoresis (PFGE), multilocus sequence typing (MLST), and MLST of virulence gene (V-MLST) methods, and evaluated the resolution abilities for typing methods. The ctxB subunit sequence analysis for all strains have shown that cholera between 1986 and 1995 was associated with mixed infections with El Tor and El Tor variants, while infections after 1996 were all caused by El Tor variant strains. Seventy V. cholerae obtained 50 PFGE patterns, with a high resolution. The strains could be divided into three groups with predominance of strains isolated during 1980s, 1990s, and 2000s, respectively, showing a good consistency with the epidemiological investigation. We also evaluated two MLST method for V. cholerae , one was used seven housekeeping genes ( adk , gyrB , metE , pntA , mdh , purM , and pyrC ), and all the isolates belonged to ST69; another was used nine housekeeping genes ( cat , chi , dnaE , gyrB , lap , pgm , recA , rstA , and gmd ). A total of seven sequence types (STs) were found by using this method for all the strains; among them, rstA gene had five alleles, recA and gmd have two alleles, and others had only one allele. The virulence gene sequence typing method ( ctxAB , tcpA , and toxR ) showed that 70 strains were divided into nine STs; among them, tcpA gene had six alleles, toxR had five alleles, while ctxAB was identical for all the strains. The latter two sequences based typing methods also had consistency with epidemiology of the strains. PFGE had a higher resolution ability compared with the sequence based typing method, and MLST used seven housekeeping genes showed the lower resolution power than nine housekeeping genes and virulence genes methods. These two sequence typing methods

  20. A numerical study of viscous vortex rings using a spectral method

    NASA Technical Reports Server (NTRS)

    Stanaway, S. K.; Cantwell, B. J.; Spalart, Philippe R.

    1988-01-01

    Viscous, axisymmetric vortex rings are investigated numerically by solving the incompressible Navier-Stokes equations using a spectral method designed for this type of flow. The results presented are axisymmetric, but the method is developed to be naturally extended to three dimensions. The spectral method relies on divergence-free basis functions. The basis functions are formed in spherical coordinates using Vector Spherical Harmonics in the angular directions, and Jacobi polynomials together with a mapping in the radial direction. Simulations are performed of a single ring over a wide range of Reynolds numbers (Re approximately equal gamma/nu), 0.001 less than or equal to 1000, and of two interacting rings. At large times, regardless of the early history of the vortex ring, it is observed that the flow approaches a Stokes solution that depends only on the total hydrodynamic impulse, which is conserved for all time. At small times, from an infinitely thin ring, the propagation speeds of vortex rings of varying Re are computed and comparisons are made with the asymptotic theory by Saffman. The results are in agreement with the theory; furthermore, the error is found to be smaller than Saffman's own estimate by a factor square root ((nu x t)/R squared) (at least for Re=0). The error also decreases with increasing Re at fixed core-to-ring radius ratio, and appears to be independent of Re as Re approaches infinity). Following a single ring, with Re=500, the vorticity contours indicate shedding of vorticity into the wake and a settling of an initially circular core to a more elliptical shape, similar to Norbury's steady inviscid vortices. Finally, we consider the case of leapfrogging vortex rings with Re=1000. The results show severe straining of the inner vortex core in the first pass and merging of the two cores during the second pass.

  1. Eigensystem analysis of classical relaxation techniques with applications to multigrid analysis

    NASA Technical Reports Server (NTRS)

    Lomax, Harvard; Maksymiuk, Catherine

    1987-01-01

    Classical relaxation techniques are related to numerical methods for solution of ordinary differential equations. Eigensystems for Point-Jacobi, Gauss-Seidel, and SOR methods are presented. Solution techniques such as eigenvector annihilation, eigensystem mixing, and multigrid methods are examined with regard to the eigenstructure.

  2. Dai-Kou type conjugate gradient methods with a line search only using gradient.

    PubMed

    Huang, Yuanyuan; Liu, Changhe

    2017-01-01

    In this paper, the Dai-Kou type conjugate gradient methods are developed to solve the optimality condition of an unconstrained optimization, they only utilize gradient information and have broader application scope. Under suitable conditions, the developed methods are globally convergent. Numerical tests and comparisons with the PRP+ conjugate gradient method only using gradient show that the methods are efficient.

  3. Beyond bilateral symmetry: geometric morphometric methods for any type of symmetry

    PubMed Central

    2011-01-01

    Background Studies of symmetric structures have made important contributions to evolutionary biology, for example, by using fluctuating asymmetry as a measure of developmental instability or for investigating the mechanisms of morphological integration. Most analyses of symmetry and asymmetry have focused on organisms or parts with bilateral symmetry. This is not the only type of symmetry in biological shapes, however, because a multitude of other types of symmetry exists in plants and animals. For instance, some organisms have two axes of reflection symmetry (biradial symmetry; e.g. many algae, corals and flowers) or rotational symmetry (e.g. sea urchins and many flowers). So far, there is no general method for the shape analysis of these types of symmetry. Results We generalize the morphometric methods currently used for the shape analysis of bilaterally symmetric objects so that they can be used for analyzing any type of symmetry. Our framework uses a mathematical definition of symmetry based on the theory of symmetry groups. This approach can be used to divide shape variation into a component of symmetric variation among individuals and one or more components of asymmetry. We illustrate this approach with data from a colonial coral that has ambiguous symmetry and thus can be analyzed in multiple ways. Our results demonstrate that asymmetric variation predominates in this dataset and that its amount depends on the type of symmetry considered in the analysis. Conclusions The framework for analyzing symmetry and asymmetry is suitable for studying structures with any type of symmetry in two or three dimensions. Studies of complex symmetries are promising for many contexts in evolutionary biology, such as fluctuating asymmetry, because these structures can potentially provide more information than structures with bilateral symmetry. PMID:21958045

  4. Classification of commutator algebras leading to the new type of closed Baker-Campbell-Hausdorff formulas

    NASA Astrophysics Data System (ADS)

    Matone, Marco

    2015-11-01

    We show that there are {\\it 13 types} of commutator algebras leading to the new closed forms of the Baker-Campbell-Hausdorff (BCH) formula $$\\exp(X)\\exp(Y)\\exp(Z)=\\exp({AX+BZ+CY+DI}) \\ , $$ derived in arXiv:1502.06589, JHEP {\\bf 1505} (2015) 113. This includes, as a particular case, $\\exp(X) \\exp(Z)$, with $[X,Z]$ containing other elements in addition to $X$ and $Z$. The algorithm exploits the associativity of the BCH formula and is based on the decomposition $\\exp(X)\\exp(Y)\\exp(Z)=\\exp(X)\\exp({\\alpha Y}) \\exp({(1-\\alpha) Y}) \\exp(Z)$, with $\\alpha$ fixed in such a way that it reduces to $\\exp({\\tilde X})\\exp({\\tilde Y})$, with $\\tilde X$ and $\\tilde Y$ satisfying the Van-Brunt and Visser condition $[\\tilde X,\\tilde Y]=\\tilde u\\tilde X+\\tilde v\\tilde Y+\\tilde cI$. It turns out that $e^\\alpha$ satisfies, in the generic case, an algebraic equation whose exponents depend on the parameters defining the commutator algebra. In nine {\\it types} of commutator algebras, such an equation leads to rational solutions for $\\alpha$. We find all the equations that characterize the solution of the above decomposition problem by combining it with the Jacobi identity.

  5. Methods for enhancing P-type doping in III-V semiconductor films

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Liu, Feng; Stringfellow, Gerald; Zhu, Junyi

    2017-08-01

    Methods of doping a semiconductor film are provided. The methods comprise epitaxially growing the III-V semiconductor film in the presence of a dopant, a surfactant capable of acting as an electron reservoir, and hydrogen, under conditions that promote the formation of a III-V semiconductor film doped with the p-type dopant. In some embodiments of the methods, the epitaxial growth of the doped III-V semiconductor film is initiated at a first hydrogen partial pressure which is increased to a second hydrogen partial pressure during the epitaxial growth process.

  6. Molecular Strain Typing of Mycobacterium tuberculosis: a Review of Frequently Used Methods

    PubMed Central

    2016-01-01

    Tuberculosis, caused by the bacterium Mycobacterium tuberculosis, remains one of the most serious global health problems. Molecular typing of M. tuberculosis has been used for various epidemiologic purposes as well as for clinical management. Currently, many techniques are available to type M. tuberculosis. Choosing the most appropriate technique in accordance with the existing laboratory conditions and the specific features of the geographic region is important. Insertion sequence IS6110-based restriction fragment length polymorphism (RFLP) analysis is considered the gold standard for the molecular epidemiologic investigations of tuberculosis. However, other polymerase chain reaction-based methods such as spacer oligonucleotide typing (spoligotyping), which detects 43 spacer sequence-interspersing direct repeats (DRs) in the genomic DR region; mycobacterial interspersed repetitive units–variable number tandem repeats, (MIRU-VNTR), which determines the number and size of tandem repetitive DNA sequences; repetitive-sequence-based PCR (rep-PCR), which provides high-throughput genotypic fingerprinting of multiple Mycobacterium species; and the recently developed genome-based whole genome sequencing methods demonstrate similar discriminatory power and greater convenience. This review focuses on techniques frequently used for the molecular typing of M. tuberculosis and discusses their general aspects and applications. PMID:27709842

  7. Molecular Strain Typing of Mycobacterium tuberculosis: a Review of Frequently Used Methods.

    PubMed

    Ei, Phyu Win; Aung, Wah Wah; Lee, Jong Seok; Choi, Go Eun; Chang, Chulhun L

    2016-11-01

    Tuberculosis, caused by the bacterium Mycobacterium tuberculosis, remains one of the most serious global health problems. Molecular typing of M. tuberculosis has been used for various epidemiologic purposes as well as for clinical management. Currently, many techniques are available to type M. tuberculosis. Choosing the most appropriate technique in accordance with the existing laboratory conditions and the specific features of the geographic region is important. Insertion sequence IS6110-based restriction fragment length polymorphism (RFLP) analysis is considered the gold standard for the molecular epidemiologic investigations of tuberculosis. However, other polymerase chain reaction-based methods such as spacer oligonucleotide typing (spoligotyping), which detects 43 spacer sequence-interspersing direct repeats (DRs) in the genomic DR region; mycobacterial interspersed repetitive units-variable number tandem repeats, (MIRU-VNTR), which determines the number and size of tandem repetitive DNA sequences; repetitive-sequence-based PCR (rep-PCR), which provides high-throughput genotypic fingerprinting of multiple Mycobacterium species; and the recently developed genome-based whole genome sequencing methods demonstrate similar discriminatory power and greater convenience. This review focuses on techniques frequently used for the molecular typing of M. tuberculosis and discusses their general aspects and applications.

  8. Domain decomposition methods for nonconforming finite element spaces of Lagrange-type

    NASA Technical Reports Server (NTRS)

    Cowsar, Lawrence C.

    1993-01-01

    In this article, we consider the application of three popular domain decomposition methods to Lagrange-type nonconforming finite element discretizations of scalar, self-adjoint, second order elliptic equations. The additive Schwarz method of Dryja and Widlund, the vertex space method of Smith, and the balancing method of Mandel applied to nonconforming elements are shown to converge at a rate no worse than their applications to the standard conforming piecewise linear Galerkin discretization. Essentially, the theory for the nonconforming elements is inherited from the existing theory for the conforming elements with only modest modification by constructing an isomorphism between the nonconforming finite element space and a space of continuous piecewise linear functions.

  9. Analysis of Typing Methods for Epidemiological Surveillance of both Methicillin-Resistant and Methicillin-Susceptible Staphylococcus aureus Strains▿ †

    PubMed Central

    Faria, Nuno A.; Carrico, João A.; Oliveira, Duarte C.; Ramirez, Mário; de Lencastre, Hermínia

    2008-01-01

    Sequence-based methods for typing Staphylococcus aureus, such as multilocus sequence typing (MLST) and spa typing, have increased interlaboratory reproducibility, portability, and speed in obtaining results, but pulsed-field gel electrophoresis (PFGE), remains the method of choice in many laboratories due to the extensive experience with this methodology and the large body of data accumulated using the technique. Comparisons between typing methods have been overwhelmingly based on a qualitative assessment of the overall agreement of results and the relative discriminatory indexes. In this study, we quantitatively assess the congruence of the major typing methods for S. aureus, using a diverse collection of 198 S. aureus strains previously characterized by PFGE, spa typing, MLST, and, in the case of methicillin-resistant S. aureus (MRSA), SCCmec typing in order to establish the quantitative congruence between the typing methods. The results of most typing methods agree in that MRSA and methicillin-susceptible S. aureus (MSSA) differ in terms of diversity of genetic backgrounds, with MSSA being more diverse. Our results show that spa typing has a very good predictive power over the clonal relationships defined by eBURST, while PFGE is less accurate for that purpose but nevertheless provides better typeability and discriminatory power. The combination of PFGE and spa typing provided even better results. Based on these observations, we suggest the use of the conjugation of spa typing and PFGE typing for epidemiological surveillance studies, since this combination provides the ability to infer long-term relationships while maintaining the discriminatory power and typeability needed in short-term studies. PMID:17989188

  10. Simulation of Needle-Type Corona Electrodes by the Finite Element Method

    NASA Astrophysics Data System (ADS)

    Yang, Shiyou; José Márcio, Machado; Nancy Mieko, Abe; Angelo, Passaro

    2007-12-01

    This paper describes a software tool, called LEVSOFT, suitable for the electric field simulations of corona electrodes by the Finite Element Method (FEM). Special attention was paid to the user friendly construction of geometries with corners and sharp points, and to the fast generation of highly refined triangular meshes and field maps. The execution of self-adaptive meshes was also implemented. These customized features make the code attractive for the simulation of needle-type corona electrodes. Some case examples involving needle type electrodes are presented.

  11. 49 CFR Appendix D to Part 173 - Test Methods for Dynamite (Explosive, Blasting, Type A)

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., Type A) D Appendix D to Part 173 Transportation Other Regulations Relating to Transportation PIPELINE... REGULATIONS SHIPPERS-GENERAL REQUIREMENTS FOR SHIPMENTS AND PACKAGINGS Pt. 173, App. D Appendix D to Part 173—Test Methods for Dynamite (Explosive, Blasting, Type A) 1. Test method D-1—Leakage Test A wooden stick...

  12. A Primer on Elliptic Functions with Applications in Classical Mechanics

    ERIC Educational Resources Information Center

    Brizard, Alain J.

    2009-01-01

    The Jacobi and Weierstrass elliptic functions used to be part of the standard mathematical arsenal of physics students. They appear as solutions of many important problems in classical mechanics: the motion of a planar pendulum (Jacobi), the motion of a force-free asymmetric top (Jacobi), the motion of a spherical pendulum (Weierstrass) and the…

  13. 77 FR 59829 - List of Nonconforming Vehicles Decided To Be Eligible for Importation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-01

    ..., the environment, public health or safety, or State, local, or Tribal governments or communities; (2... concern an environmental, health, or safety risk that NHTSA has reason to believe may have a... ..... ..... Harley Davidson (MC)......... FX, FL, XL & VR 2004 422 ..... ..... Series. Harley Davidson (MC...

  14. Parentification and Resilience among Students with Clinical and Nonclinical Aspirations: A Cross-Sectional Quantitative Study

    ERIC Educational Resources Information Center

    Yew, Wan Ping; Siau, Ching Sin; Kwong, Su Fong

    2017-01-01

    This study examined the relationship between level of parentification and resilience among students with clinical and nonclinical aspirations in Malaysia. A total of 419 college students were surveyed using the Parentification Questionnaire (Jurkovic & Thirkield, 1998) and Connor-Davidson Resilience Scale (Connor & Davidson, 2003). Results…

  15. 77 FR 24382 - Approval and Promulgation of Air Quality Implementation Plans; North Carolina; Annual Emissions...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-24

    ..., Lincoln, Rowan, and Union Counties in their entireties and Davidson Township and Coddle Creek Township in..., Durham, Forsyth, Gaston, Guilford, Mecklenburg, and Wake County, the Dutchville Township in Granville... entireties and Davidson Township and Coddle Creek Township in Iredell County to the annual emissions...

  16. Assessing and Promoting Resilience: An Additional Tool to Address the Increasing Number of College Students with Psychological Problems

    ERIC Educational Resources Information Center

    Hartley, Michael T.

    2012-01-01

    This study examined the assessment of resilience in undergraduate college students. Multigroup comparisons of the Connor-Davidson Resilience Scale (CD-RISC; Connor & Davidson, 2003) were performed on general population students and students recruited from campus mental health offices offering college counseling, psychiatric-support, and…

  17. New method to incorporate Type B uncertainty into least-squares procedures in radionuclide metrology.

    PubMed

    Han, Jubong; Lee, K B; Lee, Jong-Man; Park, Tae Soon; Oh, J S; Oh, Pil-Jei

    2016-03-01

    We discuss a new method to incorporate Type B uncertainty into least-squares procedures. The new method is based on an extension of the likelihood function from which a conventional least-squares function is derived. The extended likelihood function is the product of the original likelihood function with additional PDFs (Probability Density Functions) that characterize the Type B uncertainties. The PDFs are considered to describe one's incomplete knowledge on correction factors being called nuisance parameters. We use the extended likelihood function to make point and interval estimations of parameters in the basically same way as the least-squares function used in the conventional least-squares method is derived. Since the nuisance parameters are not of interest and should be prevented from appearing in the final result, we eliminate such nuisance parameters by using the profile likelihood. As an example, we present a case study for a linear regression analysis with a common component of Type B uncertainty. In this example we compare the analysis results obtained from using our procedure with those from conventional methods. Copyright © 2015. Published by Elsevier Ltd.

  18. Entanglement and co-tunneling of two equivalent protons in hydrogen bond pairs

    NASA Astrophysics Data System (ADS)

    Smedarchina, Zorka; Siebrand, Willem; Fernández-Ramos, Antonio

    2018-03-01

    A theoretical study is reported of a system of two identical symmetric hydrogen bonds, weakly coupled such that the two mobile protons can move either separately (stepwise) or together (concerted). It is modeled by two equivalent quartic potentials interacting through dipolar and quadrupolar coupling terms. The tunneling Hamiltonian has two imaginary modes (reaction coordinates) and a potential with a single maximum that may turn into a saddle-point of second order and two sets of (inequivalent) minima. Diagonalization is achieved via a modified Jacobi-Davidson algorithm. From this Hamiltonian the mechanism of proton transfer is derived. To find out whether the two protons move stepwise or concerted, a new tool is introduced, based on the distribution of the probability flux in the dividing plane of the transfer mode. While stepwise transfer dominates for very weak coupling, it is found that concerted transfer (co-tunneling) always occurs, even when the coupling vanishes since the symmetry of the Hamiltonian imposes permanent entanglement on the motions of the two protons. We quantify this entanglement and show that, for a wide range of parameters of interest, the lowest pair of states of the Hamiltonian represents a perfect example of highly entangled quantum states in continuous variables. The method is applied to the molecule porphycene for which the observed tunneling splitting is calculated in satisfactory agreement with experiment, and the mechanism of double-proton tunneling is found to be predominantly concerted. We show that, under normal conditions, when they are in the ground state, the two porphycene protons are highly entangled, which may have interesting applications. The treatment also identifies the conditions under which such a system can be handled by conventional one-instanton techniques.

  19. Pyocin-sensitivity testing as a method of typing Pseudomonas aeruginosa: use of "phage-free" preparations of pyocin.

    PubMed

    Rampling, A; Whitby, J L; Wildy, P

    1975-11-01

    A method for pyocin-sensitivity typing by means of "phage-free" preparations of pyocin is described. The method was tested on 227 isolates of P. aeruginosa, collected from 34 different foci of infection in hospitals in the British Isles and the results were compared with those for combined serological and phage typing of all strains and pyocin production of 105 of the isolates. It is concluded that pyocin-sensitivity typing is a simple and reliable method giving a high degree of discrimination, comparable to that of combined serological and phage typing, and it is suitable for use in routine hospital laboratories.

  20. Changing practice: red blood cell typing by molecular methods for patients with sickle cell disease.

    PubMed

    Casas, Jessica; Friedman, David F; Jackson, Tannoa; Vege, Sunitha; Westhoff, Connie M; Chou, Stella T

    2015-06-01

    Extended red blood cell (RBC) antigen matching is recommended to limit alloimmunization in patients with sickle cell disease (SCD). DNA-based testing to predict blood group phenotypes has enhanced availability of antigen-negative donor units and improved typing of transfused patients, but replacement of routine serologic typing for non-ABO antigens with molecular typing for patients has not been reported. This study compared the historical RBC antigen phenotypes obtained by hemagglutination methods with genotype predictions in 494 patients with SCD. For discrepant results, repeat serologic testing was performed and/or investigated by gene sequencing for silent or variant alleles. Seventy-one typing discrepancies were identified among 6360 antigen comparisons (1.1%). New specimens for repeat serologic testing were obtained for 66 discrepancies and retyping agreed with the genotype in 64 cases. One repeat Jk(b-) serologic phenotype, predicted Jk(b+) by genotype, was found by direct sequencing of JK to be a silenced allele, and one N typing discrepancy remains under investigation. Fifteen false-negative serologic results were associated with alleles encoding weak antigens or single-dose Fy(b) expression. DNA-based RBC typing provided improved accuracy and expanded information on RBC antigens compared to hemagglutination methods, leading to its implementation as the primary method for extended RBC typing for patients with SCD at our institution. © 2015 AABB.

  1. High-accuracy power series solutions with arbitrarily large radius of convergence for the fractional nonlinear Schrödinger-type equations

    NASA Astrophysics Data System (ADS)

    Khawaja, U. Al; Al-Refai, M.; Shchedrin, Gavriil; Carr, Lincoln D.

    2018-06-01

    Fractional nonlinear differential equations present an interplay between two common and important effective descriptions used to simplify high dimensional or more complicated theories: nonlinearity and fractional derivatives. These effective descriptions thus appear commonly in physical and mathematical modeling. We present a new series method providing systematic controlled accuracy for solutions of fractional nonlinear differential equations, including the fractional nonlinear Schrödinger equation and the fractional nonlinear diffusion equation. The method relies on spatially iterative use of power series expansions. Our approach permits an arbitrarily large radius of convergence and thus solves the typical divergence problem endemic to power series approaches. In the specific case of the fractional nonlinear Schrödinger equation we find fractional generalizations of cnoidal waves of Jacobi elliptic functions as well as a fractional bright soliton. For the fractional nonlinear diffusion equation we find the combination of fractional and nonlinear effects results in a more strongly localized solution which nevertheless still exhibits power law tails, albeit at a much lower density.

  2. Application of neutron transmutation doping method to initially p-type silicon material.

    PubMed

    Kim, Myong-Seop; Kang, Ki-Doo; Park, Sang-Jun

    2009-01-01

    The neutron transmutation doping (NTD) method was applied to the initially p-type silicon in order to extend the NTD applications at HANARO. The relationship between the irradiation neutron fluence and the final resistivity of the initially p-type silicon material was investigated. The proportional constant between the neutron fluence and the resistivity was determined to be 2.3473x10(19)nOmegacm(-1). The deviation of the final resistivity from the target for almost all the irradiation results of the initially p-type silicon ingots was at a range from -5% to 2%. In addition, the burn-up effect of the boron impurities, the residual (32)P activity and the effect of the compensation characteristics for the initially p-type silicon were studied. Conclusively, the practical methodology to perform the neutron transmutation doping of the initially p-type silicon ingot was established.

  3. A new technique for mixed-type pectus carinatum: modified Onen method.

    PubMed

    Akkas, Yucel; Kocer, Bulent; Peri, Neslihan Gulay

    2016-02-01

    We modified the Onen method for pectus carinatum repair and used a vertical incision instead of a transverse incision. The most important advantage gained by the vertical incision is that we can switch to the Ravitch method without needing an additional incision, by elongating the existing incision in patients in whom a pectus bar cannot be placed. We successfully performed the modified Onen technique in a 16-year-old boy with a mixed-type pectus carinatum deformity. © The Author(s) 2016.

  4. High Order Discontinuous Gelerkin Methods for Convection Dominated Problems with Application to Aeroacoustics

    NASA Technical Reports Server (NTRS)

    Shu, Chi-Wang

    2000-01-01

    This project is about the investigation of the development of the discontinuous Galerkin finite element methods, for general geometry and triangulations, for solving convection dominated problems, with applications to aeroacoustics. On the analysis side, we have studied the efficient and stable discontinuous Galerkin framework for small second derivative terms, for example in Navier-Stokes equations, and also for related equations such as the Hamilton-Jacobi equations. This is a truly local discontinuous formulation where derivatives are considered as new variables. On the applied side, we have implemented and tested the efficiency of different approaches numerically. Related issues in high order ENO and WENO finite difference methods and spectral methods have also been investigated. Jointly with Hu, we have presented a discontinuous Galerkin finite element method for solving the nonlinear Hamilton-Jacobi equations. This method is based on the RungeKutta discontinuous Galerkin finite element method for solving conservation laws. The method has the flexibility of treating complicated geometry by using arbitrary triangulation, can achieve high order accuracy with a local, compact stencil, and are suited for efficient parallel implementation. One and two dimensional numerical examples are given to illustrate the capability of the method. Jointly with Hu, we have constructed third and fourth order WENO schemes on two dimensional unstructured meshes (triangles) in the finite volume formulation. The third order schemes are based on a combination of linear polynomials with nonlinear weights, and the fourth order schemes are based on combination of quadratic polynomials with nonlinear weights. We have addressed several difficult issues associated with high order WENO schemes on unstructured mesh, including the choice of linear and nonlinear weights, what to do with negative weights, etc. Numerical examples are shown to demonstrate the accuracies and robustness of the

  5. Efficient block preconditioned eigensolvers for linear response time-dependent density functional theory

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vecharynski, Eugene; Brabec, Jiri; Shao, Meiyue

    Within this paper, we present two efficient iterative algorithms for solving the linear response eigenvalue problem arising from the time dependent density functional theory. Although the matrix to be diagonalized is nonsymmetric, it has a special structure that can be exploited to save both memory and floating point operations. In particular, the nonsymmetric eigenvalue problem can be transformed into an eigenvalue problem that involves the product of two matrices M and K. We show that, because MK is self-adjoint with respect to the inner product induced by the matrix K, this product eigenvalue problem can be solved efficiently by amore » modified Davidson algorithm and a modified locally optimal block preconditioned conjugate gradient (LOBPCG) algorithm that make use of the K-inner product. Additionally, the solution of the product eigenvalue problem yields one component of the eigenvector associated with the original eigenvalue problem. We show that the other component of the eigenvector can be easily recovered in an inexpensive postprocessing procedure. As a result, the algorithms we present here become more efficient than existing methods that try to approximate both components of the eigenvectors simultaneously. In particular, our numerical experiments demonstrate that the new algorithms presented here consistently outperform the existing state-of-the-art Davidson type solvers by a factor of two in both solution time and storage.« less

  6. Efficient block preconditioned eigensolvers for linear response time-dependent density functional theory

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vecharynski, Eugene; Brabec, Jiri; Shao, Meiyue

    In this article, we present two efficient iterative algorithms for solving the linear response eigenvalue problem arising from the time dependent density functional theory. Although the matrix to be diagonalized is nonsymmetric, it has a special structure that can be exploited to save both memory and floating point operations. In particular, the nonsymmetric eigenvalue problem can be transformed into an eigenvalue problem that involves the product of two matrices M and K. We show that, because MK is self-adjoint with respect to the inner product induced by the matrix K, this product eigenvalue problem can be solved efficiently by amore » modified Davidson algorithm and a modified locally optimal block preconditioned conjugate gradient (LOBPCG) algorithm that make use of the K-inner product. The solution of the product eigenvalue problem yields one component of the eigenvector associated with the original eigenvalue problem. We show that the other component of the eigenvector can be easily recovered in an inexpensive postprocessing procedure. As a result, the algorithms we present here become more efficient than existing methods that try to approximate both components of the eigenvectors simultaneously. In particular, our numerical experiments demonstrate that the new algorithms presented here consistently outperform the existing state-of-the-art Davidson type solvers by a factor of two in both solution time and storage.« less

  7. Efficient block preconditioned eigensolvers for linear response time-dependent density functional theory

    DOE PAGES

    Vecharynski, Eugene; Brabec, Jiri; Shao, Meiyue; ...

    2017-12-01

    In this article, we present two efficient iterative algorithms for solving the linear response eigenvalue problem arising from the time dependent density functional theory. Although the matrix to be diagonalized is nonsymmetric, it has a special structure that can be exploited to save both memory and floating point operations. In particular, the nonsymmetric eigenvalue problem can be transformed into an eigenvalue problem that involves the product of two matrices M and K. We show that, because MK is self-adjoint with respect to the inner product induced by the matrix K, this product eigenvalue problem can be solved efficiently by amore » modified Davidson algorithm and a modified locally optimal block preconditioned conjugate gradient (LOBPCG) algorithm that make use of the K-inner product. The solution of the product eigenvalue problem yields one component of the eigenvector associated with the original eigenvalue problem. We show that the other component of the eigenvector can be easily recovered in an inexpensive postprocessing procedure. As a result, the algorithms we present here become more efficient than existing methods that try to approximate both components of the eigenvectors simultaneously. In particular, our numerical experiments demonstrate that the new algorithms presented here consistently outperform the existing state-of-the-art Davidson type solvers by a factor of two in both solution time and storage.« less

  8. Efficient block preconditioned eigensolvers for linear response time-dependent density functional theory

    DOE PAGES

    Vecharynski, Eugene; Brabec, Jiri; Shao, Meiyue; ...

    2017-08-24

    Within this paper, we present two efficient iterative algorithms for solving the linear response eigenvalue problem arising from the time dependent density functional theory. Although the matrix to be diagonalized is nonsymmetric, it has a special structure that can be exploited to save both memory and floating point operations. In particular, the nonsymmetric eigenvalue problem can be transformed into an eigenvalue problem that involves the product of two matrices M and K. We show that, because MK is self-adjoint with respect to the inner product induced by the matrix K, this product eigenvalue problem can be solved efficiently by amore » modified Davidson algorithm and a modified locally optimal block preconditioned conjugate gradient (LOBPCG) algorithm that make use of the K-inner product. Additionally, the solution of the product eigenvalue problem yields one component of the eigenvector associated with the original eigenvalue problem. We show that the other component of the eigenvector can be easily recovered in an inexpensive postprocessing procedure. As a result, the algorithms we present here become more efficient than existing methods that try to approximate both components of the eigenvectors simultaneously. In particular, our numerical experiments demonstrate that the new algorithms presented here consistently outperform the existing state-of-the-art Davidson type solvers by a factor of two in both solution time and storage.« less

  9. Applicability of meteor radiant determination methods depending on orbit type. I. High-eccentric orbits

    NASA Astrophysics Data System (ADS)

    Svoren, J.; Neslusan, L.; Porubcan, V.

    1993-07-01

    It is evident that there is no uniform method of calculating meteor radiants which would yield reliable results for all types of cometary orbits. In the present paper an analysis of this problem is presented, together with recommended methods for various types of orbits. Some additional methods resulting from mathematical modelling are presented and discussed together with Porter's, Steel-Baggaley's and Hasegawa's methods. In order to be able to compare how suitable the application of the individual radiant determination methods is, it is necessary to determine the accuracy with which they approximate real meteor orbits. To verify the accuracy with which the orbit of a meteoroid with at least one node at 1 AU fits the original orbit of the parent body, we applied the Southworth-Hawkins D-criterion (Southworth, R.B., Hawkins, G.S.: 1963, Smithson. Contr. Astrophys 7, 261). D<=0.1 indicates a very good fit of orbits, 0.10.2 the fit is rather poor and the change of orbit unrealistic. The optimal methods with the smallest values of D for given types of orbits are shown in two series of six plots. The new method of rotation around the line of apsides we propose is very appropriate in the region of small inclinations. There is no doubt that Hasegawa's omega-adjustment method (Hasegawa, I.: 1990, Publ. Astron. Soc. Japan 42, 175) has the widest application. A comparison of the theoretical radiants with the observed radiants of seven known meteor showers is also presented.

  10. A fast semi-discrete Kansa method to solve the two-dimensional spatiotemporal fractional diffusion equation

    NASA Astrophysics Data System (ADS)

    Sun, HongGuang; Liu, Xiaoting; Zhang, Yong; Pang, Guofei; Garrard, Rhiannon

    2017-09-01

    Fractional-order diffusion equations (FDEs) extend classical diffusion equations by quantifying anomalous diffusion frequently observed in heterogeneous media. Real-world diffusion can be multi-dimensional, requiring efficient numerical solvers that can handle long-term memory embedded in mass transport. To address this challenge, a semi-discrete Kansa method is developed to approximate the two-dimensional spatiotemporal FDE, where the Kansa approach first discretizes the FDE, then the Gauss-Jacobi quadrature rule solves the corresponding matrix, and finally the Mittag-Leffler function provides an analytical solution for the resultant time-fractional ordinary differential equation. Numerical experiments are then conducted to check how the accuracy and convergence rate of the numerical solution are affected by the distribution mode and number of spatial discretization nodes. Applications further show that the numerical method can efficiently solve two-dimensional spatiotemporal FDE models with either a continuous or discrete mixing measure. Hence this study provides an efficient and fast computational method for modeling super-diffusive, sub-diffusive, and mixed diffusive processes in large, two-dimensional domains with irregular shapes.

  11. 78 FR 54182 - List of Nonconforming Vehicles Decided To Be Eligible for Importation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-03

    ... health or safety, or State, local, or Tribal governments or communities; (2) Create a serious... concern an environmental, health, or safety risk that NHTSA has reason to believe may have a...) FL Series 2010 528 Harley Davidson (MC) FX, FL, XL & VR Series......... 2004 422 Harley Davidson (MC...

  12. Highly efficient and exact method for parallelization of grid-based algorithms and its implementation in DelPhi

    PubMed Central

    Li, Chuan; Li, Lin; Zhang, Jie; Alexov, Emil

    2012-01-01

    The Gauss-Seidel method is a standard iterative numerical method widely used to solve a system of equations and, in general, is more efficient comparing to other iterative methods, such as the Jacobi method. However, standard implementation of the Gauss-Seidel method restricts its utilization in parallel computing due to its requirement of using updated neighboring values (i.e., in current iteration) as soon as they are available. Here we report an efficient and exact (not requiring assumptions) method to parallelize iterations and to reduce the computational time as a linear/nearly linear function of the number of CPUs. In contrast to other existing solutions, our method does not require any assumptions and is equally applicable for solving linear and nonlinear equations. This approach is implemented in the DelPhi program, which is a finite difference Poisson-Boltzmann equation solver to model electrostatics in molecular biology. This development makes the iterative procedure on obtaining the electrostatic potential distribution in the parallelized DelPhi several folds faster than that in the serial code. Further we demonstrate the advantages of the new parallelized DelPhi by computing the electrostatic potential and the corresponding energies of large supramolecular structures. PMID:22674480

  13. Method of the Determination of Exterior Orientation of Sensors in Hilbert Type Space.

    PubMed

    Stępień, Grzegorz

    2018-03-17

    The following article presents a new isometric transformation algorithm based on the transformation in the newly normed Hilbert type space. The presented method is based on so-called virtual translations, already known in advance, of two relative oblique orthogonal coordinate systems-interior and exterior orientation of sensors-to a common, known in both systems, point. Each of the systems is translated along its axis (the systems have common origins) and at the same time the angular relative orientation of both coordinate systems is constant. The translation of both coordinate systems is defined by the spatial norm determining the length of vectors in the new Hilbert type space. As such, the displacement of two relative oblique orthogonal systems is reduced to zero. This makes it possible to directly calculate the rotation matrix of the sensor. The next and final step is the return translation of the system along an already known track. The method can be used for big rotation angles. The method was verified in laboratory conditions for the test data set and measurement data (field data). The accuracy of the results in the laboratory test is on the level of 10 -6 of the input data. This confirmed the correctness of the assumed calculation method. The method is a further development of the author's 2017 Total Free Station (TFS) transformation to several centroids in Hilbert type space. This is the reason why the method is called Multi-Centroid Isometric Transformation-MCIT. MCIT is very fast and enables, by reducing to zero the translation of two relative oblique orthogonal coordinate systems, direct calculation of the exterior orientation of the sensors.

  14. A Machine Learning-based Method for Question Type Classification in Biomedical Question Answering.

    PubMed

    Sarrouti, Mourad; Ouatik El Alaoui, Said

    2017-05-18

    Biomedical question type classification is one of the important components of an automatic biomedical question answering system. The performance of the latter depends directly on the performance of its biomedical question type classification system, which consists of assigning a category to each question in order to determine the appropriate answer extraction algorithm. This study aims to automatically classify biomedical questions into one of the four categories: (1) yes/no, (2) factoid, (3) list, and (4) summary. In this paper, we propose a biomedical question type classification method based on machine learning approaches to automatically assign a category to a biomedical question. First, we extract features from biomedical questions using the proposed handcrafted lexico-syntactic patterns. Then, we feed these features for machine-learning algorithms. Finally, the class label is predicted using the trained classifiers. Experimental evaluations performed on large standard annotated datasets of biomedical questions, provided by the BioASQ challenge, demonstrated that our method exhibits significant improved performance when compared to four baseline systems. The proposed method achieves a roughly 10-point increase over the best baseline in terms of accuracy. Moreover, the obtained results show that using handcrafted lexico-syntactic patterns as features' provider of support vector machine (SVM) lead to the highest accuracy of 89.40 %. The proposed method can automatically classify BioASQ questions into one of the four categories: yes/no, factoid, list, and summary. Furthermore, the results demonstrated that our method produced the best classification performance compared to four baseline systems.

  15. A LSQR-type method provides a computationally efficient automated optimal choice of regularization parameter in diffuse optical tomography.

    PubMed

    Prakash, Jaya; Yalavarthy, Phaneendra K

    2013-03-01

    Developing a computationally efficient automated method for the optimal choice of regularization parameter in diffuse optical tomography. The least-squares QR (LSQR)-type method that uses Lanczos bidiagonalization is known to be computationally efficient in performing the reconstruction procedure in diffuse optical tomography. The same is effectively deployed via an optimization procedure that uses the simplex method to find the optimal regularization parameter. The proposed LSQR-type method is compared with the traditional methods such as L-curve, generalized cross-validation (GCV), and recently proposed minimal residual method (MRM)-based choice of regularization parameter using numerical and experimental phantom data. The results indicate that the proposed LSQR-type and MRM-based methods performance in terms of reconstructed image quality is similar and superior compared to L-curve and GCV-based methods. The proposed method computational complexity is at least five times lower compared to MRM-based method, making it an optimal technique. The LSQR-type method was able to overcome the inherent limitation of computationally expensive nature of MRM-based automated way finding the optimal regularization parameter in diffuse optical tomographic imaging, making this method more suitable to be deployed in real-time.

  16. PHYLOViZ: phylogenetic inference and data visualization for sequence based typing methods

    PubMed Central

    2012-01-01

    Background With the decrease of DNA sequencing costs, sequence-based typing methods are rapidly becoming the gold standard for epidemiological surveillance. These methods provide reproducible and comparable results needed for a global scale bacterial population analysis, while retaining their usefulness for local epidemiological surveys. Online databases that collect the generated allelic profiles and associated epidemiological data are available but this wealth of data remains underused and are frequently poorly annotated since no user-friendly tool exists to analyze and explore it. Results PHYLOViZ is platform independent Java software that allows the integrated analysis of sequence-based typing methods, including SNP data generated from whole genome sequence approaches, and associated epidemiological data. goeBURST and its Minimum Spanning Tree expansion are used for visualizing the possible evolutionary relationships between isolates. The results can be displayed as an annotated graph overlaying the query results of any other epidemiological data available. Conclusions PHYLOViZ is a user-friendly software that allows the combined analysis of multiple data sources for microbial epidemiological and population studies. It is freely available at http://www.phyloviz.net. PMID:22568821

  17. 76 FR 59578 - List of Nonconforming Vehicles Decided To Be Eligible for Importation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-27

    ... health or safety, or State, local, or Tribal governments or communities; (2) Create a serious... does not concern an environmental, health, or safety risk that NHTSA has reason to believe may have a.......... 1987-1997 202 Harley Davidson (MC) FL Series 2010 528 Harley Davidson (MC) FX, FL, XL & VR Series...

  18. The Secret Life of Slurs from the Perspective of Reported Speech

    ERIC Educational Resources Information Center

    Salmani Nodoushan, Mohammad Ali

    2015-01-01

    Research on reported speech is old, but scholars working in this field are inclined to see its roots in Davidson's (1968) paratactic account of indirect reports. Although Davidson aimed at a "truth-conditional" theory of indirect reports which could challenge ideational, use, and psychological theories, his paratactic view--of which the…

  19. Application of the perturbation iteration method to boundary layer type problems.

    PubMed

    Pakdemirli, Mehmet

    2016-01-01

    The recently developed perturbation iteration method is applied to boundary layer type singular problems for the first time. As a preliminary work on the topic, the simplest algorithm of PIA(1,1) is employed in the calculations. Linear and nonlinear problems are solved to outline the basic ideas of the new solution technique. The inner and outer solutions are determined with the iteration algorithm and matched to construct a composite expansion valid within all parts of the domain. The solutions are contrasted with the available exact or numerical solutions. It is shown that the perturbation-iteration algorithm can be effectively used for solving boundary layer type problems.

  20. Large-scale computation of incompressible viscous flow by least-squares finite element method

    NASA Technical Reports Server (NTRS)

    Jiang, Bo-Nan; Lin, T. L.; Povinelli, Louis A.

    1993-01-01

    The least-squares finite element method (LSFEM) based on the velocity-pressure-vorticity formulation is applied to large-scale/three-dimensional steady incompressible Navier-Stokes problems. This method can accommodate equal-order interpolations and results in symmetric, positive definite algebraic system which can be solved effectively by simple iterative methods. The first-order velocity-Bernoulli function-vorticity formulation for incompressible viscous flows is also tested. For three-dimensional cases, an additional compatibility equation, i.e., the divergence of the vorticity vector should be zero, is included to make the first-order system elliptic. The simple substitution of the Newton's method is employed to linearize the partial differential equations, the LSFEM is used to obtain discretized equations, and the system of algebraic equations is solved using the Jacobi preconditioned conjugate gradient method which avoids formation of either element or global matrices (matrix-free) to achieve high efficiency. To show the validity of this scheme for large-scale computation, we give numerical results for 2D driven cavity problem at Re = 10000 with 408 x 400 bilinear elements. The flow in a 3D cavity is calculated at Re = 100, 400, and 1,000 with 50 x 50 x 50 trilinear elements. The Taylor-Goertler-like vortices are observed for Re = 1,000.

  1. A One-Step Immunostaining Method to Visualize Rodent Muscle Fiber Type within a Single Specimen

    PubMed Central

    Sawano, Shoko; Komiya, Yusuke; Ichitsubo, Riho; Ohkawa, Yasuyuki; Nakamura, Mako; Tatsumi, Ryuichi; Ikeuchi, Yoshihide; Mizunoya, Wataru

    2016-01-01

    In this study, we present a quadruple immunostaining method for rapid muscle fiber typing of mice and rats using antibodies specific to the adult myosin heavy chain (MyHC) isoforms MyHC1, 2A, 2X, and 2B, which are common marker proteins of distinct muscle fiber types. We developed rat monoclonal antibodies specific to each MyHC isoform and conjugated these four antibodies to fluorophores with distinct excitation and emission wavelengths. By mixing the four types of conjugated antibodies, MyHC1, 2A, 2X, and 2B could be distinguished within a single specimen allowing for facile delineation of skeletal muscle fiber types. Furthermore, we could observe hybrid fibers expressing MyHC2X and MyHC2B together in single longitudinal muscle sections from mice and rats, that was not attained in previous techniques. This staining method is expected to be applied to study muscle fiber type transition in response to environmental factors, and to ultimately develop techniques to regulate animal muscle fiber types. PMID:27814384

  2. Finite Element Methods for real-time Haptic Feedback of Soft-Tissue Models in Virtual Reality Simulators

    NASA Technical Reports Server (NTRS)

    Frank, Andreas O.; Twombly, I. Alexander; Barth, Timothy J.; Smith, Jeffrey D.; Dalton, Bonnie P. (Technical Monitor)

    2001-01-01

    We have applied the linear elastic finite element method to compute haptic force feedback and domain deformations of soft tissue models for use in virtual reality simulators. Our results show that, for virtual object models of high-resolution 3D data (>10,000 nodes), haptic real time computations (>500 Hz) are not currently possible using traditional methods. Current research efforts are focused in the following areas: 1) efficient implementation of fully adaptive multi-resolution methods and 2) multi-resolution methods with specialized basis functions to capture the singularity at the haptic interface (point loading). To achieve real time computations, we propose parallel processing of a Jacobi preconditioned conjugate gradient method applied to a reduced system of equations resulting from surface domain decomposition. This can effectively be achieved using reconfigurable computing systems such as field programmable gate arrays (FPGA), thereby providing a flexible solution that allows for new FPGA implementations as improved algorithms become available. The resulting soft tissue simulation system would meet NASA Virtual Glovebox requirements and, at the same time, provide a generalized simulation engine for any immersive environment application, such as biomedical/surgical procedures or interactive scientific applications.

  3. Bovine Papillomavirus in Brazil: Detection of Coinfection of Unusual Types by a PCR-RFLP Method

    PubMed Central

    Carvalho, R. F.; Sakata, S. T.; Giovanni, D. N. S.; Mori, E.; Brandão, P. E.; Richtzenhain, L. J.; Pozzi, C. R.; Arcaro, J. R. P.; Miranda, M. S.; Mazzuchelli-de-Souza, J.; Melo, T. C.; Comenale, G.; Assaf, S. L. M. R.; Beçak, W.; Stocco, R. C.

    2013-01-01

    Bovine papillomavirus (BPV) is recognized as a causal agent of benign and malignant tumors in cattle. Thirteen types of BPV are currently characterized and classified into three distinct genera, associated with different pathological outcomes. The described BPV types as well as other putative ones have been demonstrated by molecular biology methods, mainly by the employment of degenerated PCR primers. Specifically, divergences in the nucleotide sequence of the L1 gene are useful for the identification and classification of new papillomavirus types. On the present work, a method based on the PCR-RFLP technique and DNA sequencing was evaluated as a screening tool, allowing for the detection of two relatively rare types of BPV in lesions samples from a six-year-old Holstein dairy cow, chronically affected with cutaneous papillomatosis. These findings point to the dissemination of BPVs with unclear pathogenic potential, since two relatively rare, new described BPV types, which were first characterized in Japan, were also detected in Brazil. PMID:23865043

  4. Homotopy perturbation method with Laplace Transform (LT-HPM) for solving Lane-Emden type differential equations (LETDEs).

    PubMed

    Tripathi, Rajnee; Mishra, Hradyesh Kumar

    2016-01-01

    In this communication, we describe the Homotopy Perturbation Method with Laplace Transform (LT-HPM), which is used to solve the Lane-Emden type differential equations. It's very difficult to solve numerically the Lane-Emden types of the differential equation. Here we implemented this method for two linear homogeneous, two linear nonhomogeneous, and four nonlinear homogeneous Lane-Emden type differential equations and use their appropriate comparisons with exact solutions. In the current study, some examples are better than other existing methods with their nearer results in the form of power series. The Laplace transform used to accelerate the convergence of power series and the results are shown in the tables and graphs which have good agreement with the other existing method in the literature. The results show that LT-HPM is very effective and easy to implement.

  5. Enhancing Thinking through Cooperative Learning.

    ERIC Educational Resources Information Center

    Davidson, Neil, Ed.; Worsham, Toni, Ed.

    This collection of papers provides a theoretical foundation on current practice in cooperative thinking. The papers offer many practical methods that can be applied to a full range of classroom settings. After an introduction, "HOTSICLE: Higher Order Thinking Skills in Cooperative Learning Environments" (Neil Davidson and Toni Worsham),…

  6. What's in a Name? A Comparison of Methods for Classifying Predominant Type of Maltreatment

    ERIC Educational Resources Information Center

    Lau, A.S.; Leeb, R.T.; English, D.; Graham, J.C.; Briggs, E.C.; Brody, K.E.; Marshall, J.M.

    2005-01-01

    Objective:: The primary aim of the study was to identify a classification scheme, for determining the predominant type of maltreatment in a child's history that best predicts differences in developmental outcomes. Method:: Three different predominant type classification schemes were examined in a sample of 519 children with a history of alleged…

  7. Comparison of Molecular Typing Methods Useful for Detecting Clusters of Campylobacter jejuni and C. coli Isolates through Routine Surveillance

    PubMed Central

    Taboada, Eduardo; Grant, Christopher C. R.; Blakeston, Connie; Pollari, Frank; Marshall, Barbara; Rahn, Kris; MacKinnon, Joanne; Daignault, Danielle; Pillai, Dylan; Ng, Lai-King

    2012-01-01

    Campylobacter spp. may be responsible for unreported outbreaks of food-borne disease. The detection of these outbreaks is made more difficult by the fact that appropriate methods for detecting clusters of Campylobacter have not been well defined. We have compared the characteristics of five molecular typing methods on Campylobacter jejuni and C. coli isolates obtained from human and nonhuman sources during sentinel site surveillance during a 3-year period. Comparative genomic fingerprinting (CGF) appears to be one of the optimal methods for the detection of clusters of cases, and it could be supplemented by the sequencing of the flaA gene short variable region (flaA SVR sequence typing), with or without subsequent multilocus sequence typing (MLST). Different methods may be optimal for uncovering different aspects of source attribution. Finally, the use of several different molecular typing or analysis methods for comparing individuals within a population reveals much more about that population than a single method. Similarly, comparing several different typing methods reveals a great deal about differences in how the methods group individuals within the population. PMID:22162562

  8. Equation-of-motion coupled cluster method for the description of the high spin excited states

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Musiał, Monika, E-mail: musial@ich.us.edu.pl; Lupa, Łukasz; Kucharski, Stanisław A.

    2016-04-21

    The equation-of-motion (EOM) coupled cluster (CC) approach in the version applicable for the excitation energy (EE) calculations has been formulated for high spin components. The EE-EOM-CC scheme based on the restricted Hartree-Fock reference and standard amplitude equations as used in the Davidson diagonalization procedure yields the singlet states. The triplet and higher spin components require separate amplitude equations. In the case of quintets, the relevant equations are much simpler and easier to solve. Out of 26 diagrammatic terms contributing to the R{sub 1} and R{sub 2} singlet equations in the case of quintets, only R{sub 2} operator survives with 5more » diagrammatic terms present. In addition all terms engaging three body elements of the similarity transformed Hamiltonian disappear. This indicates a substantial simplification of the theory. The implemented method has been applied to the pilot study of the excited states of the C{sub 2} molecule and quintet states of C and Si atoms.« less

  9. Advanced Diagnostics for Reacting Flows

    DTIC Science & Technology

    1991-11-20

    Ingeniera Mecanica , 17-19 Dec. 1990, Zaragosa, Spain; published in Congress Proceedings. 19. D. F. Davidson, A. Y. Chang, M. D. DiRosa and R. K. Hanson... Mecanica , 17-19 Dec. 1990, Zaragosa, Spain; published in Congress Proceedings. 14. D. F. Davidson, A. Y. Chang, M. D. DiRosa and R. K. Hanson

  10. Wiki Use That Increases Communication and Collaboration Motivation: A Reflection Several Semesters Later

    ERIC Educational Resources Information Center

    Davidson, Robyn

    2015-01-01

    The article "Wiki use that increases communication and collaboration motivation" (Davidson, 2012) appeared in the "Journal of Learning Design," Volume 5, Issue 2 in 2012. Three years on, Robyn Davidson reflects upon her original article. This article gave an account of how wikis were used as a platform to provide an opportunity…

  11. An efficient computational method for the approximate solution of nonlinear Lane-Emden type equations arising in astrophysics

    NASA Astrophysics Data System (ADS)

    Singh, Harendra

    2018-04-01

    The key purpose of this article is to introduce an efficient computational method for the approximate solution of the homogeneous as well as non-homogeneous nonlinear Lane-Emden type equations. Using proposed computational method given nonlinear equation is converted into a set of nonlinear algebraic equations whose solution gives the approximate solution to the Lane-Emden type equation. Various nonlinear cases of Lane-Emden type equations like standard Lane-Emden equation, the isothermal gas spheres equation and white-dwarf equation are discussed. Results are compared with some well-known numerical methods and it is observed that our results are more accurate.

  12. HIV-1 drug resistance prevalence, drug susceptibility and variant characterization in the Jacobi Medical Center paediatric cohort, Bronx, NY, USA.

    PubMed

    de Mulder, M; York, V A; Wiznia, A A; Michaud, H A; Nixon, D F; Holguin, A; Rosenberg, M G

    2014-03-01

    With the advent of combined antiretroviral therapy (cART), perinatally HIV-infected children are surviving into adolescence and beyond. However, drug resistance mutations (DRMs) compromise viral control, affecting the long-term effectiveness of ART. The aims of this study were to detect and identify DRMs in a HIV-1 infected paediatric cohort. Paired plasma and dried blood spots (DBSs) specimens were obtained from HIV-1 perinatally infected patients attending the Jacobi Medical Center, New York, USA. Clinical, virological and immunological data for these patients were analysed. HIV-1 pol sequences were generated from samples to identify DRMs according to the International AIDS Society (IAS) 2011 list. Forty-seven perinatally infected patients were selected, with a median age of 17.7 years, of whom 97.4% were carrying subtype B. They had a mean viral load of 3143 HIV-1 RNA copies/mL and a mean CD4 count of 486 cells/μL at the time of sampling. Nineteen patients (40.4%) had achieved undetectable viraemia (< 50 copies/mL) and 40.5% had a CD4 count of > 500 cells/μL. Most of the patients (97.9%) had received cART, including protease inhibitor (PI)-based regimens in 59.6% of cases. The DRM prevalence was 54.1, 27.6 and 27.0% for nucleoside reverse transcriptase inhibitors (NRTIs), PIs and nonnucleoside reverse transcriptase inhibitors (NNRTIs), respectively. Almost two-thirds (64.9%) of the patients harboured DRMs to at least one drug class and 5.4% were triple resistant. The mean nucleotide similarity between plasma and DBS sequences was 97.9%. Identical DRM profiles were present in 60% of plasma-DBS paired sequences. A total of 30 DRMs were detected in plasma and 26 in DBSs, with 23 present in both. Although more perinatally HIV-1-infected children are reaching adulthood as a result of advances in cART, our study cohort presented a high prevalence of resistant viruses, especially viruses resistant to NRTIs. DBS specimens can be used for DRM detection. © 2013

  13. Many tests of significance: new methods for controlling type I errors.

    PubMed

    Keselman, H J; Miller, Charles W; Holland, Burt

    2011-12-01

    There have been many discussions of how Type I errors should be controlled when many hypotheses are tested (e.g., all possible comparisons of means, correlations, proportions, the coefficients in hierarchical models, etc.). By and large, researchers have adopted familywise (FWER) control, though this practice certainly is not universal. Familywise control is intended to deal with the multiplicity issue of computing many tests of significance, yet such control is conservative--that is, less powerful--compared to per test/hypothesis control. The purpose of our article is to introduce the readership, particularly those readers familiar with issues related to controlling Type I errors when many tests of significance are computed, to newer methods that provide protection from the effects of multiple testing, yet are more powerful than familywise controlling methods. Specifically, we introduce a number of procedures that control the k-FWER. These methods--say, 2-FWER instead of 1-FWER (i.e., FWER)--are equivalent to specifying that the probability of 2 or more false rejections is controlled at .05, whereas FWER controls the probability of any (i.e., 1 or more) false rejections at .05. 2-FWER implicitly tolerates 1 false rejection and makes no explicit attempt to control the probability of its occurrence, unlike FWER, which tolerates no false rejections at all. More generally, k-FWER tolerates k - 1 false rejections, but controls the probability of k or more false rejections at α =.05. We demonstrate with two published data sets how more hypotheses can be rejected with k-FWER methods compared to FWER control.

  14. Complexity of Kronecker Operations on Sparse Matrices with Applications to the Solution of Markov Models

    NASA Technical Reports Server (NTRS)

    Buchholz, Peter; Ciardo, Gianfranco; Donatelli, Susanna; Kemper, Peter

    1997-01-01

    We present a systematic discussion of algorithms to multiply a vector by a matrix expressed as the Kronecker product of sparse matrices, extending previous work in a unified notational framework. Then, we use our results to define new algorithms for the solution of large structured Markov models. In addition to a comprehensive overview of existing approaches, we give new results with respect to: (1) managing certain types of state-dependent behavior without incurring extra cost; (2) supporting both Jacobi-style and Gauss-Seidel-style methods by appropriate multiplication algorithms; (3) speeding up algorithms that consider probability vectors of size equal to the "actual" state space instead of the "potential" state space.

  15. Periodic GMP Matrices

    NASA Astrophysics Data System (ADS)

    Eichinger, Benjamin

    2016-07-01

    We recall criteria on the spectrum of Jacobi matrices such that the corresponding isospectral torus consists of periodic operators. Motivated by those known results for Jacobi matrices, we define a new class of operators called GMP matrices. They form a certain Generalization of matrices related to the strong Moment Problem. This class allows us to give a parametrization of almost periodic finite gap Jacobi matrices by periodic GMP matrices. Moreover, due to their structural similarity we can carry over numerous results from the direct and inverse spectral theory of periodic Jacobi matrices to the class of periodic GMP matrices. In particular, we prove an analogue of the remarkable ''magic formula'' for this new class.

  16. Conjugate gradient type methods for linear systems with complex symmetric coefficient matrices

    NASA Technical Reports Server (NTRS)

    Freund, Roland

    1989-01-01

    We consider conjugate gradient type methods for the solution of large sparse linear system Ax equals b with complex symmetric coefficient matrices A equals A(T). Such linear systems arise in important applications, such as the numerical solution of the complex Helmholtz equation. Furthermore, most complex non-Hermitian linear systems which occur in practice are actually complex symmetric. We investigate conjugate gradient type iterations which are based on a variant of the nonsymmetric Lanczos algorithm for complex symmetric matrices. We propose a new approach with iterates defined by a quasi-minimal residual property. The resulting algorithm presents several advantages over the standard biconjugate gradient method. We also include some remarks on the obvious approach to general complex linear systems by solving equivalent real linear systems for the real and imaginary parts of x. Finally, numerical experiments for linear systems arising from the complex Helmholtz equation are reported.

  17. An extended affinity propagation clustering method based on different data density types.

    PubMed

    Zhao, XiuLi; Xu, WeiXiang

    2015-01-01

    Affinity propagation (AP) algorithm, as a novel clustering method, does not require the users to specify the initial cluster centers in advance, which regards all data points as potential exemplars (cluster centers) equally and groups the clusters totally by the similar degree among the data points. But in many cases there exist some different intensive areas within the same data set, which means that the data set does not distribute homogeneously. In such situation the AP algorithm cannot group the data points into ideal clusters. In this paper, we proposed an extended AP clustering algorithm to deal with such a problem. There are two steps in our method: firstly the data set is partitioned into several data density types according to the nearest distances of each data point; and then the AP clustering method is, respectively, used to group the data points into clusters in each data density type. Two experiments are carried out to evaluate the performance of our algorithm: one utilizes an artificial data set and the other uses a real seismic data set. The experiment results show that groups are obtained more accurately by our algorithm than OPTICS and AP clustering algorithm itself.

  18. Molecular typing of uropathogenic E. coli strains by the ERIC-PCR method.

    PubMed

    Ardakani, Maryam Afkhami; Ranjbar, Reza

    2016-04-01

    Escherichia coli (E. coli) is the most common cause of urinary infections in hospitals. The aim of this study was to evaluate the ERIC-PCR method for molecular typing of uropathogenic E. coli strains isolated from hospitalized patients. In a cross sectional study, 98 E. coli samples were collected from urine samples taken from patients admitted to Baqiyatallah Hospital from June 2014 to January 2015. The disk agar diffusion method was used to determine antibiotic sensitivity. DNA proliferation based on repetitive intergenic consensus was used to classify the E. coli strains. The products of proliferation were electrophoresed on 1.5% agarose gel, and their dendrograms were drawn. The data were analyzed by online Insillico software. The method used in this research proliferated numerous bands (4-17 bands), ranging from 100 to 3000 base pairs. The detected strains were classified into six clusters (E1-E6) with 70% similarity between them. In this study, uropathogenic E. coli strains belonged to different genotypic clusters. It was found that ERIC-PCR had good differentiation power for molecular typing of uropathogenic E. coli strains isolated from the patients in the study.

  19. Udzawa-type iterative method with parareal preconditioner for a parabolic optimal control problem

    NASA Astrophysics Data System (ADS)

    Lapin, A.; Romanenko, A.

    2016-11-01

    The article deals with the optimal control problem with the parabolic equation as state problem. There are point-wise constraints on the state and control functions. The objective functional involves the observation given in the domain at each moment. The conditions for convergence Udzawa's type iterative method are given. The parareal method to inverse preconditioner is given. The results of calculations are presented.

  20. A Lagrange multiplier and Hopfield-type barrier function method for the traveling salesman problem.

    PubMed

    Dang, Chuangyin; Xu, Lei

    2002-02-01

    A Lagrange multiplier and Hopfield-type barrier function method is proposed for approximating a solution of the traveling salesman problem. The method is derived from applications of Lagrange multipliers and a Hopfield-type barrier function and attempts to produce a solution of high quality by generating a minimum point of a barrier problem for a sequence of descending values of the barrier parameter. For any given value of the barrier parameter, the method searches for a minimum point of the barrier problem in a feasible descent direction, which has a desired property that lower and upper bounds on variables are always satisfied automatically if the step length is a number between zero and one. At each iteration, the feasible descent direction is found by updating Lagrange multipliers with a globally convergent iterative procedure. For any given value of the barrier parameter, the method converges to a stationary point of the barrier problem without any condition on the objective function. Theoretical and numerical results show that the method seems more effective and efficient than the softassign algorithm.

  1. A novel method for simultaneous Enterococcus species identification/typing and van genotyping by high resolution melt analysis.

    PubMed

    Gurtler, Volker; Grando, Danilla; Mayall, Barrie C; Wang, Jenny; Ghaly-Derias, Shahbano

    2012-09-01

    In order to develop a typing and identification method for van gene containing Enterococcus faecium, two multiplex PCR reactions were developed for use in HRM-PCR (High Resolution Melt-PCR): (i) vanA, vanB, vanC, vanC23 to detect van genes from different Enterococcus species; (ii) ISR (intergenic spacer region between the 16S and 23S rRNA genes) to detect all Enterococcus species and obtain species and isolate specific HRM curves. To test and validate the method three groups of isolates were tested: (i) 1672 Enterococcus species isolates from January 2009 to December 2009; (ii) 71 isolates previously identified and typed by PFGE (pulsed-field gel electrophoresis) and MLST (multi-locus sequence typing); and (iii) 18 of the isolates from (i) for which ISR sequencing was done. As well as successfully identifying 2 common genotypes by HRM from the Austin Hospital clinical isolates, this study analysed the sequences of all the vanB genes deposited in GenBank and developed a numerical classification scheme for the standardised naming of these vanB genotypes. The identification of Enterococcus faecalis from E. faecium was reliable and stable using ISR PCR. The typing of E. faecium by ISR PCR: (i) detected two variable peaks corresponding to different copy numbers of insertion sequences I and II corresponding to peak I and II respectively; (ii) produced 7 melt profiles for E. faecium with variable copy numbers of sequences I and II; (iii) demonstrated stability and instability of peak heights with equal frequency within the patient sample (36.4±4.5 days and 38.6±5.8 days respectively for 192 patients); (iv) detected ISR-HRM types with as much discrimination as PFGE and more than MLST; and (v) detected ISR-HRM types that differentiated some isolates that were identical by PFGE and MLST. In conjunction with the rapid and accurate van genotyping method described here, this ISR-HRM typing and identification method can be used as a stable identification and typing method with

  2. Automorphic Forms and Mock Modular Forms in String Theory

    NASA Astrophysics Data System (ADS)

    Nazaroglu, Caner

    We study a variety of modular invariant objects in relation to string theory. First, we focus on Jacobi forms over generic rank lattices and Siegel forms that appear in N = 2, D = 4 compactifications of heterotic string with Wilson lines. Constraints from low energy spectrum and modularity are employed to deduce the relevant supersymmetric partition functions entirely. This procedure is applied on models that lead to Jacobi forms of index 3, 4, 5 as well as Jacobi forms over root lattices A2 and A3. These computations are then checked against an explicit orbifold model which can be Higgsed to the models under question. Models with a single Wilson line are then studied in detail with their relation to paramodular group Gammam as T-duality group made explicit. These results on the heterotic string side are then turned into predictions for geometric invariants using TypeII - Heterotic duality. Secondly, we study theta functions for indenite signature lattices of generic signature. Building on results in literature for signature (n-1,1) and (n-2,2) lattices, we work out the properties of generalized error functions which we call r-tuple error functions. We then use these functions to build such indenite theta functions and describe their modular completions.

  3. Wavefronts, actions and caustics determined by the probability density of an Airy beam

    NASA Astrophysics Data System (ADS)

    Espíndola-Ramos, Ernesto; Silva-Ortigoza, Gilberto; Sosa-Sánchez, Citlalli Teresa; Julián-Macías, Israel; de Jesús Cabrera-Rosas, Omar; Ortega-Vidals, Paula; Alejandro Juárez-Reyes, Salvador; González-Juárez, Adriana; Silva-Ortigoza, Ramón

    2018-07-01

    The main contribution of the present work is to use the probability density of an Airy beam to identify its maxima with the family of caustics associated with the wavefronts determined by the level curves of a one-parameter family of solutions to the Hamilton–Jacobi equation with a given potential. To this end, we give a classical mechanics characterization of a solution of the one-dimensional Schrödinger equation in free space determined by a complete integral of the Hamilton–Jacobi and Laplace equations in free space. That is, with this type of solution, we associate a two-parameter family of wavefronts in the spacetime, which are the level curves of a one-parameter family of solutions to the Hamilton–Jacobi equation with a determined potential, and a one-parameter family of caustics. The general results are applied to an Airy beam to show that the maxima of its probability density provide a discrete set of: caustics, wavefronts and potentials. The results presented here are a natural generalization of those obtained by Berry and Balazs in 1979 for an Airy beam. Finally, we remark that, in a natural manner, each maxima of the probability density of an Airy beam determines a Hamiltonian system.

  4. Correlation and agreement between eplet mismatches calculated using serological, low-intermediate and high resolution molecular human leukocyte antigen typing methods.

    PubMed

    Fidler, Samantha; D'Orsogna, Lloyd; Irish, Ashley B; Lewis, Joshua R; Wong, Germaine; Lim, Wai H

    2018-03-02

    Structural human leukocyte antigen (HLA) matching at the eplet level can be identified by HLAMatchmaker, which requires the entry of four-digit alleles. The aim of this study was to evaluate the agreement between eplet mismatches calculated by serological and two-digit typing methods compared to high-resolution four-digit typing. In a cohort of 264 donor/recipient pairs, the evaluation of measurement error was assessed using intra-class correlation to confirm the absolute agreement between the number of eplet mismatches at class I (HLA-A, -B, C) and II loci (HLA-DQ and -DR) calculated using serological or two-digit molecular typing compared to four-digit molecular typing methods. The proportion of donor/recipient pairs with a difference of >5 eplet mismatches between the HLA typing methods was also determined. Intra-class correlation coefficients between serological and four-digit molecular typing methods were 0.969 (95% confidence intervals [95% CI] 0.960-0.975) and 0.926 (95% CI 0.899-0.944), respectively; and 0.995 (95% CI 0.994-0.996) and 0.993 (95% CI 0.991-0.995), respectively between two-digit and four-digit molecular typing methods. The proportion of donor/recipient pairs with a difference of >5 eplet mismatches at class I and II loci was 4% and 16% for serological versus four-digit molecular typing methods, and 0% and 2% for two-digit versus four-digit molecular typing methods, respectively. In this small predominantly Caucasian population, compared with serology, there is a high level of agreement in the number of eplet mismatches calculated using two-compared to four-digit molecular HLA-typing methods, suggesting that two-digit typing may be sufficient in determining eplet mismatch load in kidney transplantation.

  5. Correlation and agreement between eplet mismatches calculated using serological, low-intermediate and high resolution molecular human leukocyte antigen typing methods

    PubMed Central

    Fidler, Samantha; D’Orsogna, Lloyd; Irish, Ashley B.; Lewis, Joshua R.; Wong, Germaine; Lim, Wai H.

    2018-01-01

    Structural human leukocyte antigen (HLA) matching at the eplet level can be identified by HLAMatchmaker, which requires the entry of four-digit alleles. The aim of this study was to evaluate the agreement between eplet mismatches calculated by serological and two-digit typing methods compared to high-resolution four-digit typing. In a cohort of 264 donor/recipient pairs, the evaluation of measurement error was assessed using intra-class correlation to confirm the absolute agreement between the number of eplet mismatches at class I (HLA-A, -B, C) and II loci (HLA-DQ and -DR) calculated using serological or two-digit molecular typing compared to four-digit molecular typing methods. The proportion of donor/recipient pairs with a difference of >5 eplet mismatches between the HLA typing methods was also determined. Intra-class correlation coefficients between serological and four-digit molecular typing methods were 0.969 (95% confidence intervals [95% CI] 0.960–0.975) and 0.926 (95% CI 0.899–0.944), respectively; and 0.995 (95% CI 0.994–0.996) and 0.993 (95% CI 0.991–0.995), respectively between two-digit and four-digit molecular typing methods. The proportion of donor/recipient pairs with a difference of >5 eplet mismatches at class I and II loci was 4% and 16% for serological versus four-digit molecular typing methods, and 0% and 2% for two-digit versus four-digit molecular typing methods, respectively. In this small predominantly Caucasian population, compared with serology, there is a high level of agreement in the number of eplet mismatches calculated using two-compared to four-digit molecular HLA-typing methods, suggesting that two-digit typing may be sufficient in determining eplet mismatch load in kidney transplantation. PMID:29568344

  6. Application of physico-chemical typing methods for the epidemiological analysis of Salmonella enteritidis strains of phage type 25/17.

    PubMed Central

    Seltmann, G.; Voigt, W.; Beer, W.

    1994-01-01

    Eighty-nine Salmonella enteritidis phage type 25/17 strains isolated from a localized outbreak in the German state Nordrhein-Westfalen (outbreak NWI) could not be further differentiated by biochemotyping and plasmid pattern analysis. They were submitted to a complex typing system consisting of modern physico-chemical analytical procedures. In lipopolysaccharide pattern analysis the strains proved to be homogeneous. In multilocus enzyme electrophoresis, outer membrane and whole cell protein pattern (WCPP) analysis, and Fourier-transform infrared (FT-IR) spectroscopy (increasing extent of differentiation in the given order) strains deviating from each basal pattern were found. The extent of correspondence in these deviations was satisfactory. Forty-six strains of the same sero- and phage type, however, obtained from different outbreaks, were additionally typed. The results obtained with them indicate that the data of the first group were not restricted to strains from outbreak NWI, but of general validity. It was found that both WCPP and FT-IR represent valuable methods for the sub-grouping of bacteria. Images Fig. 1 Fig. 2 Fig. 3 PMID:7995351

  7. Molecular analysis of Acinetobacter baumannii strains isolated in Lebanon using four different typing methods.

    PubMed

    Rafei, Rayane; Dabboussi, Fouad; Hamze, Monzer; Eveillard, Matthieu; Lemarié, Carole; Gaultier, Marie-Pierre; Mallat, Hassan; Moghnieh, Rima; Husni-Samaha, Rola; Joly-Guillou, Marie-Laure; Kempf, Marie

    2014-01-01

    This study analyzed 42 Acinetobacter baumannii strains collected between 2009-2012 from different hospitals in Beyrouth and North Lebanon to better understand the epidemiology and carbapenem resistance mechanisms in our collection and to compare the robustness of pulsed field gel electrophoresis (PFGE), multilocus sequence typing (MLST), repetitive sequence-based PCR (rep-PCR) and blaOXA-51 sequence-based typing (SBT). Among 31 carbapenem resistant strains, we have detected three carbapenem resistance genes: 28 carried the blaOXA-23 gene, 1 the blaOXA-24 gene and 2 strains the blaOXA-58 gene. This is the first detection of blaOXA-23 and blaOXA-24 in Lebanon. PFGE identified 11 types and was the most discriminating technique followed by rep-PCR (9 types), blaOXA-51 SBT (8 types) and MLST (7 types). The PFGE type A'/ST2 was the dominant genotype in our collection present in Beyrouth and North Lebanon. The clustering agreement between all techniques was measured by adjust Wallace coefficient. An overall agreement has been demonstrated. High values of adjust Wallace coefficient were found with followed combinations: PFGE to predict MLST types  = 100%, PFGE to predict blaOXA-51 SBT = 100%, blaOXA-51 SBT to predict MLST = 100%, MLST to predict blaOXA-51 SBT = 84.7%, rep-PCR to predict MLST = 81.5%, PFGE to predict rep-PCR = 69% and rep-PCR to predict blaOXA-51 SBT = 67.2%. PFGE and MLST are gold standard methods for outbreaks investigation and population structure studies respectively. Otherwise, these two techniques are technically, time and cost demanding. We recommend the use of blaOXA-51 SBT as first typing method to screen isolates and assign them to their corresponding clonal lineages. Repetitive sequence-based PCR is a rapid tool to access outbreaks but careful interpretation of results must be always performed.

  8. A Novel Method for Age Estimation in Solar-Type Stars Through GALEX FUV Magnitudes

    NASA Astrophysics Data System (ADS)

    Ho, Kelly; Subramonian, Arjun; Smith, Graeme; Shouru Shieh

    2018-01-01

    Utilizing an inverse association known to exist between Galaxy Evolution Explorer (GALEX) far ultraviolet (FUV) magnitudes and the chromospheric activity of F, G, and K dwarfs, we explored a method of age estimation in solar-type stars through GALEX FUV magnitudes. Sample solar-type star data were collected from refereed publications and filtered by B-V and absolute visual magnitude to ensure similarities in temperature and luminosity to the Sun. We determined FUV-B and calculated a residual index Q for all the stars, using the temperature-induced upper bound on FUV-B as the fiducial. Plotting current age estimates for the stars against Q, we discovered a strong and significant association between the variables. By applying a log-linear transformation to the data to produce a strong correlation between Q and loge Age, we confirmed the association between Q and age to be exponential. Thus, least-squares regression was used to generate an exponential model relating Q to age in solar-type stars, which can be used by astronomers. The Q-method of stellar age estimation is simple and more efficient than existing spectroscopic methods and has applications to galactic archaeology and stellar chemical composition analysis.

  9. Method of controlling a variable geometry type turbocharger

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hirabayashi, Y.

    1988-08-23

    This patent describes a method of controlling the supercharging pressure of a variable geometry type turbocharger having a bypass, comprising the following steps which are carried out successively: receiving signals from an engine speed sensor and from an engine knocking sensor; receiving a signal from a throttle valve sensor; judging whether or not an engine is being accelerated, and proceeding to step below if the engine is being accelerated and to step below if the engine is not being accelerated, i.e., if the engine is in a constant speed operation; determining a first correction value and proceeding to step below;more » judging whether or not the engine is knocking, and proceeding to step (d) if knocking is occurring and to step (f) below if no knocking is occurring; determining a second correction value and proceeding to step; receiving signals from the engine speed sensor and from an airflow meter which measures the quantity of airflow to be supplied to the engine; calculating an airflow rate per engine revolution; determining a duty valve according to the calculated airflow rate; transmitting the corrected duty value to control means for controlling the geometry of the variable geometry type turbocharger and the opening of bypass of the turbocharger, thereby controlling the supercharging pressure of the turbocharger.« less

  10. Comparison of four molecular methods to type Salmonella Enteritidis strains.

    PubMed

    Campioni, Fábio; Pitondo-Silva, André; Bergamini, Alzira M M; Falcão, Juliana P

    2015-05-01

    This study compared the pulsed-field gel electrophoresis (PFGE), enterobacterial repetitive intergenic consensus-PCR (ERIC-PCR), multilocus variable-number of tanden-repeat analysis (MLVA), and multilocus sequence typing (MLST) methods for typing 188 Salmonella Enteritidis strains from different sources isolated over a 24-year period in Brazil. PFGE and ERIC-PCR were more efficient than MLVA for subtyping the strains. However, MLVA provided additional epidemiological information for those strains. In addition, MLST showed the Brazilian strains as belonging to the main clonal complex of S. Enteritidis, CC11, and provided the first report of two new STs in the S. enterica database but could not properly subtype the strains. Our results showed that the use of PFGE or ERIC-PCR together with MLVA is suitable to efficiently subtype S. Enteritidis strains and provide important epidemiological information. © 2015 APMIS. Published by John Wiley & Sons Ltd.

  11. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stimpson, Shane; Collins, Benjamin; Kochunas, Brendan

    The MPACT code, being developed collaboratively by the University of Michigan and Oak Ridge National Laboratory, is the primary deterministic neutron transport solver being deployed within the Virtual Environment for Reactor Applications (VERA) as part of the Consortium for Advanced Simulation of Light Water Reactors (CASL). In many applications of the MPACT code, transport-corrected scattering has proven to be an obstacle in terms of stability, and considerable effort has been made to try to resolve the convergence issues that arise from it. Most of the convergence problems seem related to the transport-corrected cross sections, particularly when used in the 2Dmore » method of characteristics (MOC) solver, which is the focus of this work. Here in this paper, the stability and performance of the 2-D MOC solver in MPACT is evaluated for two iteration schemes: Gauss-Seidel and Jacobi. With the Gauss-Seidel approach, as the MOC solver loops over groups, it uses the flux solution from the previous group to construct the inscatter source for the next group. Alternatively, the Jacobi approach uses only the fluxes from the previous outer iteration to determine the inscatter source for each group. Consequently for the Jacobi iteration, the loop over groups can be moved from the outermost loop$-$as is the case with the Gauss-Seidel sweeper$-$to the innermost loop, allowing for a substantial increase in efficiency by minimizing the overhead of retrieving segment, region, and surface index information from the ray tracing data. Several test problems are assessed: (1) Babcock & Wilcox 1810 Core I, (2) Dimple S01A-Sq, (3) VERA Progression Problem 5a, and (4) VERA Problem 2a. The Jacobi iteration exhibits better stability than Gauss-Seidel, allowing for converged solutions to be obtained over a much wider range of iteration control parameters. Additionally, the MOC solve time with the Jacobi approach is roughly 2.0-2.5× faster per sweep. While the performance and stability of

  12. Mean Field Type Control with Congestion (II): An Augmented Lagrangian Method

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Achdou, Yves, E-mail: achdou@ljll.univ-paris-diderot.fr; Laurière, Mathieu

    This work deals with a numerical method for solving a mean-field type control problem with congestion. It is the continuation of an article by the same authors, in which suitably defined weak solutions of the system of partial differential equations arising from the model were discussed and existence and uniqueness were proved. Here, the focus is put on numerical methods: a monotone finite difference scheme is proposed and shown to have a variational interpretation. Then an Alternating Direction Method of Multipliers for solving the variational problem is addressed. It is based on an augmented Lagrangian. Two kinds of boundary conditionsmore » are considered: periodic conditions and more realistic boundary conditions associated to state constrained problems. Various test cases and numerical results are presented.« less

  13. Allele-specific HLA-DR typing by mass spectrometry: an alternative to hybridization-based typing methods.

    PubMed

    Worrall, T A; Schmeckpeper, B J; Corvera, J S; Cotter, R J

    2000-11-01

    The primer oligomer base extension (PROBE) reaction, combined with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry, is used to characterize HLA-DR2 polymorphism. Alleles are distinguished rapidly and accurately by measuring the mass of primer extension products at every known variable region of HLA-DR2 alleles. Since differentiation of alleles by PROBE relies on measuring differences in extension product mass rather than differences in hybridization properties, mistyped alleles resulting from nonspecific hybridization are absent. The method shows considerable potential for high-throughput screening of HLA-DR polymorphism in a chip-based format, including rapid tissue typing of unrelated volunteer donors.

  14. Weak turbulence theory for beam-plasma interaction

    NASA Astrophysics Data System (ADS)

    Yoon, Peter H.

    2018-01-01

    The kinetic theory of weak plasma turbulence, of which Ronald C. Davidson was an important early pioneer [R. C. Davidson, Methods in Nonlinear Plasma Theory, (Academic Press, New York, 1972)], is a venerable and valid theory that may be applicable to a large number of problems in both laboratory and space plasmas. This paper applies the weak turbulence theory to the problem of gentle beam-plasma interaction and Langmuir turbulence. It is shown that the beam-plasma interaction undergoes various stages of physical processes starting from linear instability, to quasilinear saturation, to mode coupling that takes place after the quasilinear stage, followed by a state of quasi-static "turbulent equilibrium." The long term quasi-equilibrium stage is eventually perturbed by binary collisional effects in order to bring the plasma to a thermodynamic equilibrium with increased entropy.

  15. 2011 Photosynthesis Gordon Research Conference & Seminar (June 11-17, 2011, Davidson College, Davidson, North Carolina)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Prof. Krishna Niyogi

    2011-06-17

    Photosynthesis is the biological process that converts solar energy into chemical energy. Elucidation of the mechanisms of photosynthetic energy conversion at a molecular level is fundamentally important for understanding the biology of photosynthetic organisms, for optimizing biological solar fuels production, and for developing biologically inspired approaches to solar energy conversion. The 2011 Gordon Conference on Photosynthesis will present cutting-edge research focusing on the biochemical aspects of photosynthesis, including: (1) structure, assembly, and function of photosynthetic complexes; (2) the mechanism of water splitting by PSII; (3) light harvesting and quenching; (4) alternative electron transport pathways; (5) biosynthesis of pigments and cofactors;more » and (6) improvement of photosynthesis for bioenergy and food production. Reflecting the interdisciplinary nature of photosynthesis research, a diverse group of invited speakers will represent a variety of scientific approaches to investigate photosynthesis, such as biochemistry, molecular genetics, structural biology, systems biology, and spectroscopy. Highly interactive poster sessions provide opportunities for graduate students and postdocs to present their work and exchange ideas with leaders in the field. One of the highlights of the Conference is a session featuring short talks by junior investigators selected from the poster presentations. The collegial atmosphere of the Photosynthesis GRC, with programmed discussion sessions as well as informal gatherings in the afternoons and evenings, enables participants to brainstorm, exchange ideas, and forge new collaborations. For the second time, this Conference will be immediately preceded by a Gordon Research Seminar on Photosynthesis (June 11-12, 2011, at the same location), with a focus on 'Photosynthesis, Bioenergy, and the Environment.' The GRS provides an additional opportunity for graduate students and postdocs to present their research, and it provides a mechanism to encourage active participation by junior scientists interested in photosynthesis and its applications.« less

  16. Optimization of complex slater-type functions with analytic derivative methods for describing photoionization differential cross sections.

    PubMed

    Matsuzaki, Rei; Yabushita, Satoshi

    2017-05-05

    The complex basis function (CBF) method applied to various atomic and molecular photoionization problems can be interpreted as an L2 method to solve the driven-type (inhomogeneous) Schrödinger equation, whose driven term being dipole operator times the initial state wave function. However, efficient basis functions for representing the solution have not fully been studied. Moreover, the relation between their solution and that of the ordinary Schrödinger equation has been unclear. For these reasons, most previous applications have been limited to total cross sections. To examine the applicability of the CBF method to differential cross sections and asymmetry parameters, we show that the complex valued solution to the driven-type Schrödinger equation can be variationally obtained by optimizing the complex trial functions for the frequency dependent polarizability. In the test calculations made for the hydrogen photoionization problem with five or six complex Slater-type orbitals (cSTOs), their complex valued expansion coefficients and the orbital exponents have been optimized with the analytic derivative method. Both the real and imaginary parts of the solution have been obtained accurately in a wide region covering typical molecular regions. Their phase shifts and asymmetry parameters are successfully obtained by extrapolating the CBF solution from the inner matching region to the asymptotic region using WKB method. The distribution of the optimized orbital exponents in the complex plane is explained based on the close connection between the CBF method and the driven-type equation method. The obtained information is essential to constructing the appropriate basis sets in future molecular applications. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  17. Convergence Results on Iteration Algorithms to Linear Systems

    PubMed Central

    Wang, Zhuande; Yang, Chuansheng; Yuan, Yubo

    2014-01-01

    In order to solve the large scale linear systems, backward and Jacobi iteration algorithms are employed. The convergence is the most important issue. In this paper, a unified backward iterative matrix is proposed. It shows that some well-known iterative algorithms can be deduced with it. The most important result is that the convergence results have been proved. Firstly, the spectral radius of the Jacobi iterative matrix is positive and the one of backward iterative matrix is strongly positive (lager than a positive constant). Secondly, the mentioned two iterations have the same convergence results (convergence or divergence simultaneously). Finally, some numerical experiments show that the proposed algorithms are correct and have the merit of backward methods. PMID:24991640

  18. Type-2 fuzzy set extension of DEMATEL method combined with perceptual computing for decision making

    NASA Astrophysics Data System (ADS)

    Hosseini, Mitra Bokaei; Tarokh, Mohammad Jafar

    2013-05-01

    Most decision making methods used to evaluate a system or demonstrate the weak and strength points are based on fuzzy sets and evaluate the criteria with words that are modeled with fuzzy sets. The ambiguity and vagueness of the words and different perceptions of a word are not considered in these methods. For this reason, the decision making methods that consider the perceptions of decision makers are desirable. Perceptual computing is a subjective judgment method that considers that words mean different things to different people. This method models words with interval type-2 fuzzy sets that consider the uncertainty of the words. Also, there are interrelations and dependency between the decision making criteria in the real world; therefore, using decision making methods that cannot consider these relations is not feasible in some situations. The Decision-Making Trail and Evaluation Laboratory (DEMATEL) method considers the interrelations between decision making criteria. The current study used the combination of DEMATEL and perceptual computing in order to improve the decision making methods. For this reason, the fuzzy DEMATEL method was extended into type-2 fuzzy sets in order to obtain the weights of dependent criteria based on the words. The application of the proposed method is presented for knowledge management evaluation criteria.

  19. An Analysis of the Metrics Used in the United States Navy’s Enlisted Supply Chain As They Apply to the Royal Australian Navy

    DTIC Science & Technology

    2012-12-01

    and Hill, 1988; Williamson, 1981), enhances socialization (Edwards, 1979), and lowers transaction costs ( Mahoney , 1992; Williamson, 1975). It does...much information as possible about its workforce to ensure it is managed effectively and efficiently (Davidson & Newman , 2006). Data measurement of...112 Cappelli, P. (2009b). A Supply Chain Approach to Workforce Planning. Organizational Dynamics, 38(1), 8–15. Davidson, G., & Newman , E

  20. On conjugate gradient type methods and polynomial preconditioners for a class of complex non-Hermitian matrices

    NASA Technical Reports Server (NTRS)

    Freund, Roland

    1988-01-01

    Conjugate gradient type methods are considered for the solution of large linear systems Ax = b with complex coefficient matrices of the type A = T + i(sigma)I where T is Hermitian and sigma, a real scalar. Three different conjugate gradient type approaches with iterates defined by a minimal residual property, a Galerkin type condition, and an Euclidian error minimization, respectively, are investigated. In particular, numerically stable implementations based on the ideas behind Paige and Saunder's SYMMLQ and MINRES for real symmetric matrices are proposed. Error bounds for all three methods are derived. It is shown how the special shift structure of A can be preserved by using polynomial preconditioning. Results on the optimal choice of the polynomial preconditioner are given. Also, some numerical experiments for matrices arising from finite difference approximations to the complex Helmholtz equation are reported.

  1. Error analysis and correction of lever-type stylus profilometer based on Nelder-Mead Simplex method

    NASA Astrophysics Data System (ADS)

    Hu, Chunbing; Chang, Suping; Li, Bo; Wang, Junwei; Zhang, Zhongyu

    2017-10-01

    Due to the high measurement accuracy and wide range of applications, lever-type stylus profilometry is commonly used in industrial research areas. However, the error caused by the lever structure has a great influence on the profile measurement, thus this paper analyzes the error of high-precision large-range lever-type stylus profilometry. The errors are corrected by the Nelder-Mead Simplex method, and the results are verified by the spherical surface calibration. It can be seen that this method can effectively reduce the measurement error and improve the accuracy of the stylus profilometry in large-scale measurement.

  2. An Approximate Model for the Performance and Acoustic Predictions of Counterrotating Propeller Configurations. M.S. Thesis

    NASA Technical Reports Server (NTRS)

    Denner, Brett William

    1989-01-01

    An approximate method was developed to analyze and predict the acoustics of a counterrotating propeller configuration. The method employs the analytical techniques of Lock and Theodorsen as described by Davidson to predict the steady performance of a counterrotating configuration. Then, a modification of the method of Lesieutre is used to predict the unsteady forces on the blades. Finally, the steady and unsteady loads are used in the numerical method of Succi to predict the unsteady acoustics of the propeller. The numerical results are compared with experimental acoustic measurements of a counterrotating propeller configuration by Gazzaniga operating under several combinations of advance ratio, blade pitch, and number of blades. In addition, a constant-speed commuter-class propeller configuration was designed with the Davidson method and the acoustics analyzed at three advance ratios. Noise levels and frequency spectra were calculated at a number of locations around the configuration. The directivity patterns of the harmonics in both the horizontal and vertical planes were examined, with the conclusion that the noise levels of the even harmonics are relatively independent of direction whereas the noise levels of the odd harmonics are extremely dependent on azimuthal direction in the horizontal plane. The equations of Succi are examined to explain this behavior.

  3. Development of a neutronics calculation method for designing commercial type Japanese sodium-cooled fast reactor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Takeda, T.; Shimazu, Y.; Hibi, K.

    2012-07-01

    Under the R and D project to improve the modeling accuracy for the design of fast breeder reactors the authors are developing a neutronics calculation method for designing a large commercial type sodium- cooled fast reactor. The calculation method is established by taking into account the special features of the reactor such as the use of annular fuel pellet, inner duct tube in large fuel assemblies, large core. The Verification and Validation, and Uncertainty Qualification (V and V and UQ) of the calculation method is being performed by using measured data from the prototype FBR Monju. The results of thismore » project will be used in the design and analysis of the commercial type demonstration FBR, known as the Japanese Sodium fast Reactor (JSFR). (authors)« less

  4. Optimization of radial-type superconducting magnetic bearing using the Taguchi method

    NASA Astrophysics Data System (ADS)

    Ai, Liwang; Zhang, Guomin; Li, Wanjie; Liu, Guole; Liu, Qi

    2018-07-01

    It is important and complicated to model and optimize the levitation behavior of superconducting magnetic bearing (SMB). That is due to the nonlinear constitutive relationships of superconductor and ferromagnetic materials, the relative movement between the superconducting stator and PM rotor, and the multi-parameter (e.g., air-gap, critical current density, and remanent flux density, etc.) affecting the levitation behavior. In this paper, we present a theoretical calculation and optimization method of the levitation behavior for radial-type SMB. A simplified model of levitation force calculation is established using 2D finite element method with H-formulation. In the model, the boundary condition of superconducting stator is imposed by harmonic series expressions to describe the traveling magnetic field generated by the moving PM rotor. Also, experimental measurements of the levitation force are performed and validate the model method. A statistical method called Taguchi method is adopted to carry out an optimization of load capacity for SMB. Then the factor effects of six optimization parameters on the target characteristics are discussed and the optimum parameters combination is determined finally. The results show that the levitation behavior of SMB is greatly improved and the Taguchi method is suitable for optimizing the SMB.

  5. Development of a multiplex PCR-based rapid typing method for enterohemorrhagic Escherichia coli O157 strains.

    PubMed

    Ooka, Tadasuke; Terajima, Jun; Kusumoto, Masahiro; Iguchi, Atsushi; Kurokawa, Ken; Ogura, Yoshitoshi; Asadulghani, Md; Nakayama, Keisuke; Murase, Kazunori; Ohnishi, Makoto; Iyoda, Sunao; Watanabe, Haruo; Hayashi, Tetsuya

    2009-09-01

    Enterohemorrhagic Escherichia coli O157 (EHEC O157) is a food-borne pathogen that has raised worldwide public health concern. The development of simple and rapid strain-typing methods is crucial for the rapid detection and surveillance of EHEC O157 outbreaks. In the present study, we developed a multiplex PCR-based strain-typing method for EHEC O157, which is based on the variability in genomic location of IS629 among EHEC O157 strains. This method is very simple, in that the procedures are completed within 2 h, the analysis can be performed without the need for special equipment or techniques (requiring only conventional PCR and agarose gel electrophoresis systems), the results can easily be transformed into digital data, and the genes for the major virulence markers of EHEC O157 (the stx(1), stx(2), and eae genes) can be detected simultaneously. Using this method, 201 EHEC O157 strains showing different XbaI digestion patterns in pulsed-field gel electrophoresis (PFGE) analysis were classified into 127 types, and outbreak-related strains showed identical or highly similar banding patterns. Although this method is less discriminatory than PFGE, it may be useful as a primary screening tool for EHEC O157 outbreaks.

  6. Strain typing of acetic acid bacteria responsible for vinegar production by the submerged elaboration method.

    PubMed

    Fernández-Pérez, Rocío; Torres, Carmen; Sanz, Susana; Ruiz-Larrea, Fernanda

    2010-12-01

    Strain typing of 103 acetic acid bacteria isolates from vinegars elaborated by the submerged method from ciders, wines and spirit ethanol, was carried on in this study. Two different molecular methods were utilised: pulsed field gel electrophoresis (PFGE) of total DNA digests with a number of restriction enzymes, and enterobacterial repetitive intergenic consensus (ERIC) - PCR analysis. The comparative study of both methods showed that restriction fragment PFGE of SpeI digests of total DNA was a suitable method for strain typing and for determining which strains were present in vinegar fermentations. Results showed that strains of the species Gluconacetobacter europaeus were the most frequent leader strains of fermentations by the submerged method in the studied vinegars, and among them strain R1 was the predominant one. Results showed as well that mixed populations (at least two different strains) occurred in vinegars from cider and wine, whereas unique strains were found in spirit vinegars, which offered the most stressing conditions for bacterial growth. Copyright © 2010 Elsevier Ltd. All rights reserved.

  7. Comparison of four methods of differential typing of isolates of Shigella sonnei.

    PubMed Central

    Helgason, S.; Old, D. C.

    1981-01-01

    accurate epidemiological tracing of strains of Sh. sonnei in a community, resistotyping, the technique showing the greatest discrimination and least variability of the four tested, should be included as the principal typing method. Images Plate 1 PMID:7031123

  8. The study of dielectric relaxation in aqueous carbohydrates solutions using time domain reflectometry technique

    NASA Astrophysics Data System (ADS)

    Hudge, Pravin G.; Lokhande, Milind P.; Kumbharkhane, Ashok C.

    2012-09-01

    Complex permittivity spectra of aqueous solutions of monosaccharide ( d-glucose) and disaccharides ( d-sucrose) in the frequency range from 10 MHz to 30 GHz at various concentrations and temperatures have been determined using time domain reflectometry technique. The complex dielectric permittivity spectrum of d-glucose and d-sucrose in water shows Cole-Davidson type behaviour. Dielectric constant (ɛ0) and relaxation time (τ), Kirkwood correlation factor, activation enthalpy and entropy parameters have been determined.

  9. Perceived Dual Method Responsibilities by Relationship Type Among African-American Male Adolescents.

    PubMed

    Gilliam, Melissa; Woodhams, Elisabeth; Sipsma, Heather; Hill, Brandon

    2017-03-01

    To describe the extent to which African-American male adolescents perceive responsibility for contraception and condom use and to understand the perceived importance of dual method use for respondents in casual versus committed relationships. Data were collected using surveys informed by formative focus group sessions. Participants included African-American male high-school students aged 14-19 years from the Chicago's South Side. Respondents were surveyed regarding contraceptive behavioral intentions and perceived importance of dual method use. Responses were compared by relationship type. Logistic regression modeling was used to determine the association between contraception responsibility and perceiving dual method protection as important for each sexual relationship type. Sample included 348 young men (mean age: 16.1 years; mean age at first sex: 13.8 years). Among those who had heard of condoms (99.4%) and withdrawal (90.4%), most reported liking these methods (83.7% and 53.9%). Participants were more likely to report greater responsibility within a committed relationship for all perceived contraceptive responsibilities (e.g., going with partner to get contraception). Participants were more likely to engage in conversation about pregnancy prevention with a committed partner. Among sexually active respondents, perceived contraceptive responsibility was associated with perceiving dual protection as very important (odds ratio = 1.58; 95% confidence interval = 1.05-2.38). Respondents felt partially responsible for pregnancy prevention, particularly within committed relationships, and were open to using dual protection. However, many respondents had low levels of contraception knowledge. These findings indicate that male African-American adolescents might benefit from increased education and support around contraception methods and condom use. Copyright © 2016 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

  10. Joyce McLaren | NREL

    Science.gov Websites

    . Golden, CO: National Renewable Energy Laboratory. NREL/TP-6A20-64852. McLaren, J. 2015. Reaching 100 Laboratory. NREL/BR-6A20-62490. McLaren J., C. Davidson, J. Miller, and L. Bird. "Impact of Rate Design . Davidson, J. McLaren, and J. Miller. 2015. Impact of Rate Design Alternatives on Residential Solar Customer

  11. A new extrapolation cascadic multigrid method for three dimensional elliptic boundary value problems

    NASA Astrophysics Data System (ADS)

    Pan, Kejia; He, Dongdong; Hu, Hongling; Ren, Zhengyong

    2017-09-01

    In this paper, we develop a new extrapolation cascadic multigrid method, which makes it possible to solve three dimensional elliptic boundary value problems with over 100 million unknowns on a desktop computer in half a minute. First, by combining Richardson extrapolation and quadratic finite element (FE) interpolation for the numerical solutions on two-level of grids (current and previous grids), we provide a quite good initial guess for the iterative solution on the next finer grid, which is a third-order approximation to the FE solution. And the resulting large linear system from the FE discretization is then solved by the Jacobi-preconditioned conjugate gradient (JCG) method with the obtained initial guess. Additionally, instead of performing a fixed number of iterations as used in existing cascadic multigrid methods, a relative residual tolerance is introduced in the JCG solver, which enables us to obtain conveniently the numerical solution with the desired accuracy. Moreover, a simple method based on the midpoint extrapolation formula is proposed to achieve higher-order accuracy on the finest grid cheaply and directly. Test results from four examples including two smooth problems with both constant and variable coefficients, an H3-regular problem as well as an anisotropic problem are reported to show that the proposed method has much better efficiency compared to the classical V-cycle and W-cycle multigrid methods. Finally, we present the reason why our method is highly efficient for solving these elliptic problems.

  12. Level set immersed boundary method for gas-liquid-solid interactions with phase-change

    NASA Astrophysics Data System (ADS)

    Dhruv, Akash; Balaras, Elias; Riaz, Amir; Kim, Jungho

    2017-11-01

    We will discuss an approach to simulate the interaction between two-phase flows with phase changes and stationary/moving structures. In our formulation, the Navier-Stokes and heat advection-diffusion equations are solved on a block-structured grid using adaptive mesh refinement (AMR) along with sharp jump in pressure, velocity and temperature across the interface separating the different phases. The jumps are implemented using a modified Ghost Fluid Method (Lee et al., J. Comput. Physics, 344:381-418, 2017), and the interface is tracked with a level set approach. Phase transition is achieved by calculating mass flux near the interface and extrapolating it to the rest of the domain using a Hamilton-Jacobi equation. Stationary/moving structures are simulated with an immersed boundary formulation based on moving least squares (Vanella & Balaras, J. Comput. Physics, 228:6617-6628, 2009). A variety of canonical problems involving vaporization, film boiling and nucleate boiling is presented to validate the method and demonstrate the its formal accuracy. The robustness of the solver in complex problems, which are crucial in efficient design of heat transfer mechanisms for various applications, will also be demonstrated. Work supported by NASA, Grant NNX16AQ77G.

  13. Method for producing high carrier concentration p-Type transparent conducting oxides

    DOEpatents

    Li, Xiaonan; Yan, Yanfa; Coutts, Timothy J.; Gessert, Timothy A.; Dehart, Clay M.

    2009-04-14

    A method for producing transparent p-type conducting oxide films without co-doping plasma enhancement or high temperature comprising: a) introducing a dialkyl metal at ambient temperature and a saturated pressure in a carrier gas into a low pressure deposition chamber, and b) introducing NO alone or with an oxidizer into the chamber under an environment sufficient to produce a metal-rich condition to enable NO decomposition and atomic nitrogen incorporation into the formed transparent metal conducting oxide.

  14. Dynamic Restarting Schemes for Eigenvalue Problems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wu, Kesheng; Simon, Horst D.

    1999-03-10

    In studies of restarted Davidson method, a dynamic thick-restart scheme was found to be excellent in improving the overall effectiveness of the eigen value method. This paper extends the study of the dynamic thick-restart scheme to the Lanczos method for symmetric eigen value problems and systematically explore a range of heuristics and strategies. We conduct a series of numerical tests to determine their relative strength and weakness on a class of electronic structure calculation problems.

  15. A PROOF OF CONVERGENCE OF THE HORN AND SCHUNCK OPTICAL FLOW ALGORITHM IN ARBITRARY DIMENSION

    PubMed Central

    LE TARNEC, LOUIS; DESTREMPES, FRANÇOIS; CLOUTIER, GUY; GARCIA, DAMIEN

    2013-01-01

    The Horn and Schunck (HS) method, which amounts to the Jacobi iterative scheme in the interior of the image, was one of the first optical flow algorithms. In this article, we prove the convergence of the HS method, whenever the problem is well-posed. Our result is shown in the framework of a generalization of the HS method in dimension n ≥ 1, with a broad definition of the discrete Laplacian. In this context, the condition for the convergence is that the intensity gradients are not all contained in a same hyperplane. Two other articles ([17] and [13]) claimed to solve this problem in the case n = 2, but it appears that both of these proofs are erroneous. Moreover, we explain why some standard results on the convergence of the Jacobi method do not apply for the HS problem, unless n = 1. It is also shown that the convergence of the HS scheme implies the convergence of the Gauss-Seidel and SOR schemes for the HS problem. PMID:26097625

  16. Koopmans' theorem in the Hartree-Fock method. General formulation

    NASA Astrophysics Data System (ADS)

    Plakhutin, Boris N.

    2018-03-01

    This work presents a general formulation of Koopmans' theorem (KT) in the Hartree-Fock (HF) method which is applicable to molecular and atomic systems with arbitrary orbital occupancies and total electronic spin including orbitally degenerate (OD) systems. The new formulation is based on the full set of variational conditions imposed upon the HF orbitals by the variational principle for the total energy and the conditions imposed by KT on the orbitals of an ionized electronic shell [B. N. Plakhutin and E. R. Davidson, J. Chem. Phys. 140, 014102 (2014)]. Based on these conditions, a general form of the restricted open-shell HF method is developed, whose eigenvalues (orbital energies) obey KT for the whole energy spectrum. Particular attention is paid to the treatment of OD systems, for which the new method gives a number of unexpected results. For example, the present method gives four different orbital energies for the triply degenerate atomic level 2p in the second row atoms B to F. Based on both KT conditions and a parallel treatment of atoms B to F within a limited configuration interaction approach, we prove that these four orbital energies, each of which is triply degenerate, are related via KT to the energies of different spin-dependent ionization and electron attachment processes (2p)N → (2p ) N ±1. A discussion is also presented of specific limitations of the validity of KT in the HF method which arise in OD systems. The practical applicability of the theory is verified by comparing KT estimates of the ionization potentials I2s and I2p for the second row open-shell atoms Li to F with the relevant experimental data.

  17. A new species of Burumoseria Csiki, 1939 from Taiwan, with redescription of the genus and new generic synonym (Coleoptera: Chrysomelidae: Galerucinae: Alticini)

    USDA-ARS?s Scientific Manuscript database

    The Oriental genus Burumoseria Csiki is redescribed. A new species, Burumoseria yuae from Taiwan is described and illustrated. A key to Burumoseria species is provided. The Oriental and Australian genus Licyllus Jacoby 1885 is synonymized with Thrasychroma Jacoby 1885....

  18. Solution of D dimensional Dirac equation for hyperbolic tangent potential using NU method and its application in material properties

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Suparmi, A., E-mail: soeparmi@staff.uns.ac.id; Cari, C., E-mail: cari@staff.uns.ac.id; Pratiwi, B. N., E-mail: namakubetanurpratiwi@gmail.com

    2016-02-08

    The analytical solution of D-dimensional Dirac equation for hyperbolic tangent potential is investigated using Nikiforov-Uvarov method. In the case of spin symmetry the D dimensional Dirac equation reduces to the D dimensional Schrodinger equation. The D dimensional relativistic energy spectra are obtained from D dimensional relativistic energy eigen value equation by using Mat Lab software. The corresponding D dimensional radial wave functions are formulated in the form of generalized Jacobi polynomials. The thermodynamically properties of materials are generated from the non-relativistic energy eigen-values in the classical limit. In the non-relativistic limit, the relativistic energy equation reduces to the non-relativistic energy.more » The thermal quantities of the system, partition function and specific heat, are expressed in terms of error function and imaginary error function which are numerically calculated using Mat Lab software.« less

  19. An overview of various typing methods for clinical epidemiology of the emerging pathogen Stenotrophomonas maltophilia.

    PubMed

    Gherardi, Giovanni; Creti, Roberta; Pompilio, Arianna; Di Bonaventura, Giovanni

    2015-03-01

    Typing of bacterial isolates has been used for decades to study local outbreaks as well as in national and international surveillances for monitoring newly emerging resistant clones. Despite being recognized as a nosocomial pathogen, the precise modes of transmission of Stenotrophomonas maltophilia in health care settings are unknown. Due to the high genetic diversity observed among S. maltophilia clinical isolates, the typing results might be better interpreted if also environmental strains were included. This could help to identify preventative measures to be designed and implemented for decreasing the possibility of outbreaks and nosocomial infections. In this review, we attempt to provide an overview on the most common typing methods used for clinical epidemiology of S. maltophilia strains, such as PCR-based fingerprinting analyses, pulsed-field gel electrophoresis, multilocus variable number tandem repeat analysis, and multilocus sequence type. Application of the proteomic-based mass spectrometry by matrix-assisted laser desorption ionization-time of flight is also described. Improvements of typing methods already in use have to be achieved to facilitate S. maltophilia infection control at any level. In the near future, when novel Web-based platforms for rapid data processing and analysis will be available, whole genome sequencing technologies will likely become a highly powerful tool for outbreak investigations and surveillance studies in routine clinical practices. Copyright © 2015 Elsevier Inc. All rights reserved.

  20. Algorithm-Eigenvalue Estimation of Hyperspectral Wishart Covariance Matrices from a Limited Number of Samples

    DTIC Science & Technology

    2015-03-01

    ALGORITHM—EIGENVALUE ESTIMATION OF HYPERSPECTRAL WISHART COVARIANCE MATRICES FROM A LIMITED NUMBER OF SAMPLES ECBC-TN-067 Avishai Ben- David ...NUMBER 6. AUTHOR(S) Ben- David , Avishai (ECBC) and Davidson, Charles E. (STC) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7...and published by Avishai Ben- David and Charles E. Davidson (Eigenvalue Estimation of Hyperspectral WishartCovariance Matrices from Limited Number of

  1. Parity among interpretation methods of MLEE patterns and disparity among clustering methods in epidemiological typing of Candida albicans.

    PubMed

    Boriollo, Marcelo Fabiano Gomes; Rosa, Edvaldo Antonio Ribeiro; Gonçalves, Reginaldo Bruno; Höfling, José Francisco

    2006-03-01

    The typing of C. albicans by MLEE (multilocus enzyme electrophoresis) is dependent on the interpretation of enzyme electrophoretic patterns, and the study of the epidemiological relationships of these yeasts can be conducted by cluster analysis. Therefore, the aims of the present study were to first determine the discriminatory power of genetic interpretation (deduction of the allelic composition of diploid organisms) and numerical interpretation (mere determination of the presence and absence of bands) of MLEE patterns, and then to determine the concordance (Pearson product-moment correlation coefficient) and similarity (Jaccard similarity coefficient) of the groups of strains generated by three cluster analysis models, and the discriminatory power of such models as well [model A: genetic interpretation, genetic distance matrix of Nei (d(ij)) and UPGMA dendrogram; model B: genetic interpretation, Dice similarity matrix (S(D1)) and UPGMA dendrogram; model C: numerical interpretation, Dice similarity matrix (S(D2)) and UPGMA dendrogram]. MLEE was found to be a powerful and reliable tool for the typing of C. albicans due to its high discriminatory power (>0.9). Discriminatory power indicated that numerical interpretation is a method capable of discriminating a greater number of strains (47 versus 43 subtypes), but also pointed to model B as a method capable of providing a greater number of groups, suggesting its use for the typing of C. albicans by MLEE and cluster analysis. Very good agreement was only observed between the elements of the matrices S(D1) and S(D2), but a large majority of the groups generated in the three UPGMA dendrograms showed similarity S(J) between 4.8% and 75%, suggesting disparities in the conclusions obtained by the cluster assays.

  2. Numerical investigation of performance of vane-type propellant management device by VOF methods

    NASA Astrophysics Data System (ADS)

    Liu, J. T.; Zhou, C.; Wu, Y. L.; Zhuang, B. T.; Li, Y.

    2015-01-01

    The orbital propellant management performance of the vane-type tank is so important for the propellant system and it determines the lifetime of the satellite. The propellant in the tank can be extruded by helium gas. To study the two phase distribution in the vane-type surface tension tank and the capability of the vane-type propellant management device (PMD), a large volume vane-type surface tension tank is analysed using 3-D unsteady numerical simulations. VOF methods are used to analyse the location of the interface of the two phase. Performances of the propellant acquisition vanes and propellant refillable reservoir in the tank are investigated. The flow conductivity of the propellant acquisition vanes and the liquid storage capacity of propellant refillable reservoir can be affected by the value of the gravity and the volume of the propellant in the tank. To avoid the large resistance causing by surface tension in an outflow of a small hole, the design of the vanes in a propellant refillable reservoir should have suitable space.

  3. Spectral ’Fingerprinting’ of Phytoplankton Populations by Two-Dimensional Fluorescence and Fourier-Transform-Based Pattern Recognition.

    DTIC Science & Technology

    1985-07-08

    comparison to a library of known spectra. A preliminary study (Warner et al., 1984) of the application of this method to the pattern recognition of...case, the spectra from two blue-green algae are shown. Figure 3A indicates phycocyanin as the major fluorophore and 3B indicates phycoerythrin. Except...445. Ho, C.H., G.D. Christian, and E.R. Davidson, 1978. Application of the method of rank annihilation to quantitative analyses of multicomponent

  4. Axisymmetric analysis of a tube-type acoustic levitator by a finite element method.

    PubMed

    Hatano, H

    1994-01-01

    A finite element approach was taken for the study of the sound field and positioning force in a tube-type acoustic levitator. An axisymmetric model, where a rigid sphere is suspended on the tube axis, was introduced to model a cylindrical chamber of a levitation tube furnace. Distributions of velocity potential, magnitudes of positioning force, and resonance frequency shifts of the chamber due to the presence of the sphere were numerically estimated in relation to the sphere's position and diameter. Experiments were additionally made to compare with the simulation. The finite element method proved to be a useful tool for analyzing and designing the tube-type levitator.

  5. Hawking Radiation from a Spherically Symmetric Static Black Hole

    NASA Astrophysics Data System (ADS)

    Dai, Qian; Liu, Wenbiao

    2007-08-01

    The massive particles’ Hawking radiation from a spherically symmetric static black hole is investigated with Parikh-Wilczek method, Hamilton Jacobi method and Damour Ruffini’s method. When energy conservation is considered, the same result can be concluded that the radiation spectrum is not precisely thermal. The corrected spectrum is consistent to the underlying unitary quantum theory, which can be used to explain the information loss paradox possibly.

  6. How Distinctive Processing Enhances Hits and Reduces False Alarms

    PubMed Central

    Hunt, R. Reed; Smith, Rebekah E.

    2015-01-01

    Distinctive processing is a concept designed to account for precision in memory, both correct responses and avoidance of errors. The principal question addressed in two experiments is how distinctive processing of studied material reduces false alarms to familiar distractors. Jacoby (Jacoby, Kelley, & McElree, 1999) has used the metaphors early selection and late correction to describe two different types of control processes. Early selection refers to limitations on access whereas late correction describes controlled monitoring of accessed information. The two types of processes are not mutually exclusive, and previous research has provided evidence for the operation of both. The data reported here extend previous work to a criterial recollection paradigm and to a recognition memory test. The results of both experiments show that variables that reduce false memory for highly familiar distracters continue to exert their effect under conditions of minimal post-access monitoring. Level of monitoring was reduced in the first experiment through test instructions and in the second experiment through speeded test responding. The results were consistent with the conclusion that both early selection and late correction operate to control accuracy in memory. PMID:26034343

  7. ZZ-Type a posteriori error estimators for adaptive boundary element methods on a curve☆

    PubMed Central

    Feischl, Michael; Führer, Thomas; Karkulik, Michael; Praetorius, Dirk

    2014-01-01

    In the context of the adaptive finite element method (FEM), ZZ-error estimators named after Zienkiewicz and Zhu (1987) [52] are mathematically well-established and widely used in practice. In this work, we propose and analyze ZZ-type error estimators for the adaptive boundary element method (BEM). We consider weakly singular and hyper-singular integral equations and prove, in particular, convergence of the related adaptive mesh-refining algorithms. Throughout, the theoretical findings are underlined by numerical experiments. PMID:24748725

  8. Real-Time PCR Typing of Escherichia coli Based on Multiple Single Nucleotide Polymorphisms--a Convenient and Rapid Method.

    PubMed

    Lager, Malin; Mernelius, Sara; Löfgren, Sture; Söderman, Jan

    2016-01-01

    Healthcare-associated infections caused by Escherichia coli and antibiotic resistance due to extended-spectrum beta-lactamase (ESBL) production constitute a threat against patient safety. To identify, track, and control outbreaks and to detect emerging virulent clones, typing tools of sufficient discriminatory power that generate reproducible and unambiguous data are needed. A probe based real-time PCR method targeting multiple single nucleotide polymorphisms (SNP) was developed. The method was based on the multi locus sequence typing scheme of Institute Pasteur and by adaptation of previously described typing assays. An 8 SNP-panel that reached a Simpson's diversity index of 0.95 was established, based on analysis of sporadic E. coli cases (ESBL n = 27 and non-ESBL n = 53). This multi-SNP assay was used to identify the sequence type 131 (ST131) complex according to the Achtman's multi locus sequence typing scheme. However, it did not fully discriminate within the complex but provided a diagnostic signature that outperformed a previously described detection assay. Pulsed-field gel electrophoresis typing of isolates from a presumed outbreak (n = 22) identified two outbreaks (ST127 and ST131) and three different non-outbreak-related isolates. Multi-SNP typing generated congruent data except for one non-outbreak-related ST131 isolate. We consider multi-SNP real-time PCR typing an accessible primary generic E. coli typing tool for rapid and uniform type identification.

  9. Efficient Numerical Diagonalization of Hermitian 3 × 3 Matrices

    NASA Astrophysics Data System (ADS)

    Kopp, Joachim

    A very common problem in science is the numerical diagonalization of symmetric or hermitian 3 × 3 matrices. Since standard "black box" packages may be too inefficient if the number of matrices is large, we study several alternatives. We consider optimized implementations of the Jacobi, QL, and Cuppen algorithms and compare them with an alytical method relying on Cardano's formula for the eigenvalues and on vector cross products for the eigenvectors. Jacobi is the most accurate, but also the slowest method, while QL and Cuppen are good general purpose algorithms. The analytical algorithm outperforms the others by more than a factor of 2, but becomes inaccurate or may even fail completely if the matrix entries differ greatly in magnitude. This can mostly be circumvented by using a hybrid method, which falls back to QL if conditions are such that the analytical calculation might become too inaccurate. For all algorithms, we give an overview of the underlying mathematical ideas, and present detailed benchmark results. C and Fortran implementations of our code are available for download from .

  10. Legendre spectral-collocation method for solving some types of fractional optimal control problems

    PubMed Central

    Sweilam, Nasser H.; Al-Ajami, Tamer M.

    2014-01-01

    In this paper, the Legendre spectral-collocation method was applied to obtain approximate solutions for some types of fractional optimal control problems (FOCPs). The fractional derivative was described in the Caputo sense. Two different approaches were presented, in the first approach, necessary optimality conditions in terms of the associated Hamiltonian were approximated. In the second approach, the state equation was discretized first using the trapezoidal rule for the numerical integration followed by the Rayleigh–Ritz method to evaluate both the state and control variables. Illustrative examples were included to demonstrate the validity and applicability of the proposed techniques. PMID:26257937

  11. Spectral analysis of early-type stars using a genetic algorithm based fitting method

    NASA Astrophysics Data System (ADS)

    Mokiem, M. R.; de Koter, A.; Puls, J.; Herrero, A.; Najarro, F.; Villamariz, M. R.

    2005-10-01

    We present the first automated fitting method for the quantitative spectroscopy of O- and early B-type stars with stellar winds. The method combines the non-LTE stellar atmosphere code fastwind from Puls et al. (2005, A&A, 435, 669) with the genetic algorithm based optimization routine pikaia from Charbonneau (1995, ApJS, 101, 309), allowing for a homogeneous analysis of upcoming large samples of early-type stars (e.g. Evans et al. 2005, A&A, 437, 467). In this first implementation we use continuum normalized optical hydrogen and helium lines to determine photospheric and wind parameters. We have assigned weights to these lines accounting for line blends with species not taken into account, lacking physics, and/or possible or potential problems in the model atmosphere code. We find the method to be robust, fast, and accurate. Using our method we analysed seven O-type stars in the young cluster Cyg OB2 and five other Galactic stars with high rotational velocities and/or low mass loss rates (including 10 Lac, ζ Oph, and τ Sco) that have been studied in detail with a previous version of fastwind. The fits are found to have a quality that is comparable or even better than produced by the classical “by eye” method. We define errorbars on the model parameters based on the maximum variations of these parameters in the models that cluster around the global optimum. Using this concept, for the investigated dataset we are able to recover mass-loss rates down to ~6 × 10-8~M⊙ yr-1 to within an error of a factor of two, ignoring possible systematic errors due to uncertainties in the continuum normalization. Comparison of our derived spectroscopic masses with those derived from stellar evolutionary models are in very good agreement, i.e. based on the limited sample that we have studied we do not find indications for a mass discrepancy. For three stars we find significantly higher surface gravities than previously reported. We identify this to be due to differences in

  12. An optimized full-configuration-interaction nuclear orbital approach to a ``hard-core'' interaction problem: Application to (3He)N-Cl2(B) clusters (N<=4)

    NASA Astrophysics Data System (ADS)

    de Lara-Castells, M. P.; Villarreal, P.; Delgado-Barrio, G.; Mitrushchenkov, A. O.

    2009-11-01

    An efficient full-configuration-interaction nuclear orbital treatment has been recently developed as a benchmark quantum-chemistry-like method to calculate ground and excited "solvent" energies and wave functions in small doped ΔEest clusters (N ≤4) [M. P. de Lara-Castells, G. Delgado-Barrio, P. Villarreal, and A. O. Mitrushchenkov, J. Chem. Phys. 125, 221101 (2006)]. Additional methodological and computational details of the implementation, which uses an iterative Jacobi-Davidson diagonalization algorithm to properly address the inherent "hard-core" He-He interaction problem, are described here. The convergence of total energies, average pair He-He interaction energies, and relevant one- and two-body properties upon increasing the angular part of the one-particle basis set (expanded in spherical harmonics) has been analyzed, considering Cl2 as the dopant and a semiempirical model (T-shaped) He-Cl2(B) potential. Converged results are used to analyze global energetic and structural aspects as well as the configuration makeup of the wave functions, associated with the ground and low-lying "solvent" excited states. Our study reveals that besides the fermionic nature of H3e atoms, key roles in determining total binding energies and wave-function structures are played by the strong repulsive core of the He-He potential as well as its very weak attractive region, the most stable arrangement somehow departing from the one of N He atoms equally spaced on equatorial "ring" around the dopant. The present results for N =4 fermions indicates the structural "pairing" of two H3e atoms at opposite sides on a broad "belt" around the dopant, executing a sort of asymmetric umbrella motion. This pairing is a compromise between maximizing the H3e-H3e and the He-dopant attractions, and suppressing at the same time the "hard-core" repulsion. Although the He-He attractive interaction is rather weak, its contribution to the total energy is found to scale as a power of three and it thus

  13. Determination for Davidson Exterior Trim/Textron

    EPA Pesticide Factsheets

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  14. Comparison of a gel column blood typing method and a point-of-care cartridge for dog erythrocyte antigen 1.1.

    PubMed

    Blois, Shauna L; Richardson, Danielle M; Abrams-Ogg, Anthony C G

    2013-01-01

    Blood typing for the presence of Dog Erythrocyte Antigen (DEA) 1.1 is recommended in all donor and recipient dogs prior to transfusion of blood products. The objective of this study was to determine if a point-of-care DEA 1.1 blood typing cartridge could be used in place of the gel column typing method. Detection of DEA 1.1 was performed using a laboratory-based gel column method and a point-of-care cartridge. A convenience sample of 30 healthy blood donors, 13 dogs with immune-mediated hemolytic anemia (IMHA) (3 of which had concurrent immune-mediated thrombocytopenia [IMT]), and 44 dogs with other diseases was included in the study. Agreement was observed between the tests for normal dogs and dogs with nonimmune-mediated disease in 74/74 cases. Two dogs in the IMHA group had indeterminate gel column blood typing results; 1 dog in this group had a negative gel column test result but a positive cartridge test result. There was good agreement between the 2 methods for normal dogs and dogs with nonimmune-mediated disease. Blood typing methods in dogs with IMHA should be further investigated. © Veterinary Emergency and Critical Care Society 2013.

  15. Scale-Up of Lubricant Mixing Process by Using V-Type Blender Based on Discrete Element Method.

    PubMed

    Horibe, Masashi; Sonoda, Ryoichi; Watano, Satoru

    2018-01-01

    A method for scale-up of a lubricant mixing process in a V-type blender was proposed. Magnesium stearate was used for the lubricant, and the lubricant mixing experiment was conducted using three scales of V-type blenders (1.45, 21 and 130 L) under the same fill level and Froude (Fr) number. However, the properties of lubricated mixtures and tablets could not correspond with the mixing time or the total revolution number. To find the optimum scale-up factor, discrete element method (DEM) simulations of three scales of V-type blender mixing were conducted, and the total travel distance of particles under the different scales was calculated. The properties of the lubricated mixture and tablets obtained from the scale-up experiment were well correlated with the mixing time determined by the total travel distance. It was found that a scale-up simulation based on the travel distance of particles is valid for the lubricant mixing scale-up processes.

  16. Various methods of determining the natural frequencies and damping of composite cantilever plates. 2. Approximate solution by Galerkin's method for the trinomial model of damping

    NASA Astrophysics Data System (ADS)

    Ekel'chik, V. S.; Ryabov, V. M.

    1997-01-01

    The application of Kantorovich's method to a trinomial model of deformation taking into account transverse bending of a plate leads to a connected system of three ordinary differential equations of fourth order with respect to three unknown functions of the longitudinal coordinate and to the coresponding boundary conditions for them at the fixed end and on the free edge. For the approximate calculation of the frequencies and forms of natural vibrations Galerkin's method is used, and as coordinate functions we chose orthogonal Jacobi polynomials with weight function. The dimensionless frequencies depend on the magnitude of the four dimensionless complexes, three of which characterize the anisotropy of the elastic properties of the composite. For the fibrous composites used at present we determined the possible range of change of the dimensionless complexes d16 and d26 attained by oblique placement. The article examines the influence of the angle of reinforcement on some first dimensionless frequencies of a plate made of unidirectional carbon reinforced plastic. It also analyzes the asymptotics of the frequencies when the length of the plate is increased, and it shows that for strongly anisotropic material with the structure [ϕ]T the frequencies of the flexural as well as of the torsional vibrations may be substantially lower when flexural-torsional interaction is taken into account.

  17. Comparative study of mobility extraction methods in p-type polycrystalline silicon thin film transistors

    NASA Astrophysics Data System (ADS)

    Liu, Kai; Liu, Yuan; Liu, Yu-Rong; En, Yun-Fei; Li, Bin

    2017-07-01

    Channel mobility in the p-type polycrystalline silicon thin film transistors (poly-Si TFTs) is extracted using Hoffman method, linear region transconductance method and multi-frequency C-V method. Due to the non-negligible errors when neglecting the dependence of gate-source voltage on the effective mobility, the extracted mobility results are overestimated using linear region transconductance method and Hoffman method, especially in the lower gate-source voltage region. By considering of the distribution of localized states in the band-gap, the frequency independent capacitance due to localized charges in the sub-gap states and due to channel free electron charges in the conduction band were extracted using multi-frequency C-V method. Therefore, channel mobility was extracted accurately based on the charge transport theory. In addition, the effect of electrical field dependent mobility degradation was also considered in the higher gate-source voltage region. In the end, the extracted mobility results in the poly-Si TFTs using these three methods are compared and analyzed.

  18. Standardization of Type 2 Diabetes Outpatient Expenditure with Bundled Payment Method in China

    PubMed Central

    Xu, Guo-Chao; Luo, Yun; Li, Qian; Wu, Meng-Fan; Zhou, Zi-Jun

    2016-01-01

    Background: In recent years, the prevalence of type 2 diabetes among Chinese population has been increasing by years, directly leading to an average annual growth rate of 19.90% of medical expenditure. Therefore, it is urgent to work on strategies to control the growth of medical expenditure on type 2 diabetes on the basis of the reality of China. Therefore, in this study, we explored the feasibility of implementing bundled payment in China through analyzing bundled payment standards of type 2 diabetes outpatient services. Methods: This study analyzed the outpatient expenditure on type 2 diabetes with Beijing Urban Employee's Basic Medical Insurance from 2010 to 2012. Based on the analysis of outpatient expenditure and its influential factors, we adopted decision tree approach to conduct a case-mix analysis. In the end, we built a case-mix model to calculate the standard expenditure and the upper limit of each combination. Results: We found that age, job status, and whether with complication were significant factors that influence outpatient expenditure for type 2 diabetes. Through the analysis of the decision tree, we used six variables (complication, age, diabetic foot, diabetic nephropathy, cardiac-cerebrovascular disease, and neuropathy) to group the cases, and obtained 11 case-mix groups. Conclusions: We argued that it is feasible to implement bundled payment on type 2 diabetes outpatient services. Bundled payment is effective to control the increase of outpatient expenditure. Further improvements are needed for the implementation of bundled payment reimbursement standards, together with relevant policies and measures. PMID:27064041

  19. Advantages of a validated UPLC-MS/MS standard addition method for the quantification of A-type dimeric and trimeric proanthocyanidins in cranberry extracts in comparison with well-known quantification methods.

    PubMed

    van Dooren, Ines; Foubert, Kenn; Theunis, Mart; Naessens, Tania; Pieters, Luc; Apers, Sandra

    2018-01-30

    The berries of Vaccinium macrocarpon, cranberry, are widely used for the prevention of urinary tract infections. This species contains A-type proanthocyanidins (PACs), which intervene in the initial phase of the development of urinary tract infections by preventing the adherence of Escherichia coli by their P-type fimbriae to uroepithelial cells. Unfortunately, the existing clinical studies used different cranberry preparations, which were poorly standardized. Because of this, the results were hard to compare, which led sometimes to conflicting results. Currently, PACs are quantified using the rather non-specific spectrophotometric 4-dimethylaminocinnamaldehyde (DMAC) method. In addition, a normal phase HPTLC-densitometric method, a HPLC-UV method and three LC-MS/MS methods for quantification of procyanidin A2 were recently published. All these methods contain some shortcomings and errors. Hence, the development and validation of a fast and sensitive standard addition LC-MS/MS method for the simultaneous quantification of A-type dimers and trimers in a cranberry dry extract was carried out. A linear calibration model could be adopted for dimers and, after logaritmic transformation, for trimers. The maximal interday and interconcentration precision was found to be 4.86% and 4.28% for procyanidin A2, and 5.61% and 7.65% for trimeric PACs, which are all acceptable values for an analytical method using LC-MS/MS. In addition, twelve different cranberry extracts were analyzed by means of the newly validated method and other widely used methods. There appeared to be an enormous variation in dimeric and trimeric PAC content. Comparison of these results with LC-MS/MS analysis without standard addition showed the presence of matrix effects for some of the extracts and proved the necessity of standard addition. A comparison of the well-known and widely used DMAC method, the butanol-HCl assay and this newly developed LC-MS/MS method clearly indicated the need for a reliable

  20. Retrieval Constraints on the Front End Create Differences in Recollection on a Subsequent Test

    ERIC Educational Resources Information Center

    Marsh, Richard L.; Meeks, J. Thadeus; Cook, Gabriel I.; Clark-Foos, Arlo; Hicks, Jason L.; Brewer, Gene A.

    2009-01-01

    Four experiments were conducted to investigate how the cognitive control of memory retrieval selects particular qualitative characteristics as a consequence of instantiating a retrieval mode for recognition memory. Adapting the memory for foils paradigm from Jacoby, Shimizu, Daniels, and Rhodes (Jacoby, L. L., Shimizu, Y., Daniels, K. A., &…

  1. Elaborative Processing in the Korsakoff Syndrome: Context versus Habit

    ERIC Educational Resources Information Center

    Van Damme, Ilse; d'Ydewalle, Gery

    2008-01-01

    Using a procedure of Hay and Jacoby [Hay, J. F., & Jacoby, L. L. (1999). "Separating habit and recollection in young and older adults: Effects of elaborative processing and distinctiveness." "Psychology and Aging," 14, 122-134], Korsakoff patients' capacity to encode and retrieve elaborative, semantic information was investigated. Habits were…

  2. Analytical Solutions for the Resonance Response of Goupillaud-type Elastic Media Using Z-transform Methods

    DTIC Science & Technology

    2012-02-01

    using z-transform methods. The determinant of the resulting global system matrix in the z-space |Am| is a palindromic polynomial with real...resulting global system matrix in the z-space |Am| is a palindromic polynomial with real coefficients. The zeros of the palindromic polynomial are distinct...Goupillaud-type multilayered media. In addition, the present treatment uses a global matrix method that is attributed to Knopoff [16], rather than the

  3. Workshop report on large-scale matrix diagonalization methods in chemistry theory institute

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bischof, C.H.; Shepard, R.L.; Huss-Lederman, S.

    The Large-Scale Matrix Diagonalization Methods in Chemistry theory institute brought together 41 computational chemists and numerical analysts. The goal was to understand the needs of the computational chemistry community in problems that utilize matrix diagonalization techniques. This was accomplished by reviewing the current state of the art and looking toward future directions in matrix diagonalization techniques. This institute occurred about 20 years after a related meeting of similar size. During those 20 years the Davidson method continued to dominate the problem of finding a few extremal eigenvalues for many computational chemistry problems. Work on non-diagonally dominant and non-Hermitian problems asmore » well as parallel computing has also brought new methods to bear. The changes and similarities in problems and methods over the past two decades offered an interesting viewpoint for the success in this area. One important area covered by the talks was overviews of the source and nature of the chemistry problems. The numerical analysts were uniformly grateful for the efforts to convey a better understanding of the problems and issues faced in computational chemistry. An important outcome was an understanding of the wide range of eigenproblems encountered in computational chemistry. The workshop covered problems involving self- consistent-field (SCF), configuration interaction (CI), intramolecular vibrational relaxation (IVR), and scattering problems. In atomic structure calculations using the Hartree-Fock method (SCF), the symmetric matrices can range from order hundreds to thousands. These matrices often include large clusters of eigenvalues which can be as much as 25% of the spectrum. However, if Cl methods are also used, the matrix size can be between 10{sup 4} and 10{sup 9} where only one or a few extremal eigenvalues and eigenvectors are needed. Working with very large matrices has lead to the development of« less

  4. Study of a Vocal Feature Selection Method and Vocal Properties for Discriminating Four Constitution Types

    PubMed Central

    Kim, Keun Ho; Ku, Boncho; Kang, Namsik; Kim, Young-Su; Jang, Jun-Su; Kim, Jong Yeol

    2012-01-01

    The voice has been used to classify the four constitution types, and to recognize a subject's health condition by extracting meaningful physical quantities, in traditional Korean medicine. In this paper, we propose a method of selecting the reliable variables from various voice features, such as frequency derivative features, frequency band ratios, and intensity, from vowels and a sentence. Further, we suggest a process to extract independent variables by eliminating explanatory variables and reducing their correlation and remove outlying data to enable reliable discriminant analysis. Moreover, the suitable division of data for analysis, according to the gender and age of subjects, is discussed. Finally, the vocal features are applied to a discriminant analysis to classify each constitution type. This method of voice classification can be widely used in the u-Healthcare system of personalized medicine and for improving diagnostic accuracy. PMID:22529874

  5. Evaluation of a Method Using Three Genomic Guided Escherichia coli Markers for Phylogenetic Typing of E. coli Isolates of Various Genetic Backgrounds

    PubMed Central

    Hamamoto, Kouta; Ueda, Shuhei; Yamamoto, Yoshimasa

    2015-01-01

    Genotyping and characterization of bacterial isolates are essential steps in the identification and control of antibiotic-resistant bacterial infections. Recently, one novel genotyping method using three genomic guided Escherichia coli markers (GIG-EM), dinG, tonB, and dipeptide permease (DPP), was reported. Because GIG-EM has not been fully evaluated using clinical isolates, we assessed this typing method with 72 E. coli collection of reference (ECOR) environmental E. coli reference strains and 63 E. coli isolates of various genetic backgrounds. In this study, we designated 768 bp of dinG, 745 bp of tonB, and 655 bp of DPP target sequences for use in the typing method. Concatenations of the processed marker sequences were used to draw GIG-EM phylogenetic trees. E. coli isolates with identical sequence types as identified by the conventional multilocus sequence typing (MLST) method were localized to the same branch of the GIG-EM phylogenetic tree. Sixteen clinical E. coli isolates were utilized as test isolates without prior characterization by conventional MLST and phylogenetic grouping before GIG-EM typing. Of these, 14 clinical isolates were assigned to a branch including only isolates of a pandemic clone, E. coli B2-ST131-O25b, and these results were confirmed by conventional typing methods. Our results suggested that the GIG-EM typing method and its application to phylogenetic trees might be useful tools for the molecular characterization and determination of the genetic relationships among E. coli isolates. PMID:25809972

  6. High-Speed Coating Method for Photovoltaic Textiles with Closed-Type Die Coater

    NASA Astrophysics Data System (ADS)

    Imai, Takahiko; Shibayama, Norihisa; Takamatsu, Seiichi; Shiraishi, Kenji; Marumoto, Kazuhiro; Itoh, Toshihiro

    2013-06-01

    We developed a closed-type die-coating method to fabricate thin films for electronic devices. We succeeded in the die-coating of poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS) water dispersions and regioregular poly(3-hexylthiophene):[6,6]-phenyl C61-butyric acid methyl ester (P3HT:PCBM) solution to fabricate thin films of these organic materials with extremely high speeds of 5 and 20 m/min, respectively. The film thicknesses were evaluated by cross-sectional scanning electron microscopy (SEM). The deviations of the film thicknesses from our target values were less than 5%. We fabricated Al/P3HT:PCBM/PEDOT:PSS/indium tin oxide (ITO)/poly(ethylene terephthalate) (PET) textiles as an example of an application of the method, and the photovoltaic characteristic of the devices was confirmed.

  7. Optimal Low-Thrust Limited-Power Transfers between Arbitrary Elliptic Coplanar Orbits

    NASA Technical Reports Server (NTRS)

    daSilvaFernandes, Sandro; dasChagasCarvalho, Francisco

    2007-01-01

    In this work, a complete first order analytical solution, which includes the short periodic terms, for the problem of optimal low-thrust limited-power transfers between arbitrary elliptic coplanar orbits in a Newtonian central gravity field is obtained through Hamilton-Jacobi theory and a perturbation method based on Lie series.

  8. On Time

    NASA Astrophysics Data System (ADS)

    Cattaneo, Alberto S.; Schiavina, Michele

    2017-02-01

    This note describes the restoration of time in one-dimensional parameterization-invariant (hence timeless) models, namely, the classically equivalent Jacobi action and gravity coupled to matter. It also serves as a timely introduction by examples to the classical and quantum BV-BFV formalism as well as to the AKSZ method.

  9. Descriptions of eight new species of Phaelota (Coleoptera: Chrysomelidae) with a new generic synonymy and a key to species of Indian subcontinent

    USDA-ARS?s Scientific Manuscript database

    Six new species of Phaelota Jacoby from India viz. P. assamensis, P. kottigehara, P. maculipennis, P. mauliki, P. saluki, and P. viridipennis and two new species from Sri Lanka viz. P. ogloblini and P. schereri are described and illustrated. Thrylaea Jacoby is treated as a new junior synonym of Phae...

  10. "Xchanges Journal"--Web Journal as the Writing Classroom: On Building an Academic Web Journal in a Collaborative Classroom

    ERIC Educational Resources Information Center

    Boles, Jacoby; Newmark, Julianne

    2011-01-01

    This website is the creation of one of Julianne Newmark's students, Jacoby Boles, the Editorial Assistant for the e-journal "Xchanges." Jacoby reflects, via this site, on his experiences as a member of the Technical Communication 371 "Publications Management" course at New Mexico Tech. This course was explicitly designed to…

  11. Development of a method for urine bikunin/urinary trypsin inhibitor (UTI) quantitation and structural characterization: Application to type 1 and type 2 diabetes.

    PubMed

    Lepedda, Antonio Junior; Nieddu, Gabriele; Rocchiccioli, Silvia; Fresu, Pietro; De Muro, Pierina; Formato, Marilena

    2013-12-01

    Bikunin is a plasma proteinase inhibitor often associated with inflammatory conditions. It has a half-life of few minutes and it is rapidly excreted into urine as urinary trypsin inhibitor (UTI). UTI levels are usually low in healthy individuals but they can increase up to tenfold in both acute and chronic inflammatory diseases. This article describes a sensitive method for both direct UTI quantitation and structural characterization. UTI purification was performed by anion exchange micro-chromatography followed by SDS-PAGE. A calibration curve for protein quantitation was set up by using a purified UTI fraction. UTI identification and structural characterization was performed by Nano-LC-MS/MS analysis. The method was applied on urine samples from 9 patients with type 1 diabetes, 11 patients with type 2 diabetes, and 28 healthy controls, matched for age and sex with patients, evidencing higher UTI levels in both groups of patients with respect to controls (p < 0.001 and p = 0.001, respectively). Spearman's correlation tests highlighted no association between UTI levels and age in each group tested. Owing to the elevated sensitivity and specificity, the described method allows UTI quantitation from very low quantities of specimen. Furthermore, as UTI concentration is normalized for creatinine level, the analysis could be also performed on randomly collected urine samples. Finally, MS/MS analysis prospects the possibility of characterizing PTM sites potentially able to affect UTI localization, function, and pathophysiological activity. Preliminary results suggest that UTI levels could represent a useful marker of chronic inflammatory condition in type 1 and 2 diabetes. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  12. Review and International Recommendation of Methods for Typing Neisseria gonorrhoeae Isolates and Their Implications for Improved Knowledge of Gonococcal Epidemiology, Treatment, and Biology

    PubMed Central

    Unemo, Magnus; Dillon, Jo-Anne R.

    2011-01-01

    Summary: Gonorrhea, which may become untreatable due to multiple resistance to available antibiotics, remains a public health problem worldwide. Precise methods for typing Neisseria gonorrhoeae, together with epidemiological information, are crucial for an enhanced understanding regarding issues involving epidemiology, test of cure and contact tracing, identifying core groups and risk behaviors, and recommending effective antimicrobial treatment, control, and preventive measures. This review evaluates methods for typing N. gonorrhoeae isolates and recommends various methods for different situations. Phenotypic typing methods, as well as some now-outdated DNA-based methods, have limited usefulness in differentiating between strains of N. gonorrhoeae. Genotypic methods based on DNA sequencing are preferred, and the selection of the appropriate genotypic method should be guided by its performance characteristics and whether short-term epidemiology (microepidemiology) or long-term and/or global epidemiology (macroepidemiology) matters are being investigated. Currently, for microepidemiological questions, the best methods for fast, objective, portable, highly discriminatory, reproducible, typeable, and high-throughput characterization are N. gonorrhoeae multiantigen sequence typing (NG-MAST) or full- or extended-length porB gene sequencing. However, pulsed-field gel electrophoresis (PFGE) and Opa typing can be valuable in specific situations, i.e., extreme microepidemiology, despite their limitations. For macroepidemiological studies and phylogenetic studies, DNA sequencing of chromosomal housekeeping genes, such as multilocus sequence typing (MLST), provides a more nuanced understanding. PMID:21734242

  13. New clustered regularly interspaced short palindromic repeat locus spacer pair typing method based on the newly incorporated spacer for Salmonella enterica.

    PubMed

    Li, Hao; Li, Peng; Xie, Jing; Yi, Shengjie; Yang, Chaojie; Wang, Jian; Sun, Jichao; Liu, Nan; Wang, Xu; Wu, Zhihao; Wang, Ligui; Hao, Rongzhang; Wang, Yong; Jia, Leili; Li, Kaiqin; Qiu, Shaofu; Song, Hongbin

    2014-08-01

    A clustered regularly interspaced short palindromic repeat (CRISPR) typing method has recently been developed and used for typing and subtyping of Salmonella spp., but it is complicated and labor intensive because it has to analyze all spacers in two CRISPR loci. Here, we developed a more convenient and efficient method, namely, CRISPR locus spacer pair typing (CLSPT), which only needs to analyze the two newly incorporated spacers adjoining the leader array in the two CRISPR loci. We analyzed a CRISPR array of 82 strains belonging to 21 Salmonella serovars isolated from humans in different areas of China by using this new method. We also retrieved the newly incorporated spacers in each CRISPR locus of 537 Salmonella isolates which have definite serotypes in the Pasteur Institute's CRISPR Database to evaluate this method. Our findings showed that this new CLSPT method presents a high level of consistency (kappa = 0.9872, Matthew's correlation coefficient = 0.9712) with the results of traditional serotyping, and thus, it can also be used to predict serotypes of Salmonella spp. Moreover, this new method has a considerable discriminatory power (discriminatory index [DI] = 0.8145), comparable to those of multilocus sequence typing (DI = 0.8088) and conventional CRISPR typing (DI = 0.8684). Because CLSPT only costs about $5 to $10 per isolate, it is a much cheaper and more attractive method for subtyping of Salmonella isolates. In conclusion, this new method will provide considerable advantages over other molecular subtyping methods, and it may become a valuable epidemiologic tool for the surveillance of Salmonella infections. Copyright © 2014, American Society for Microbiology. All Rights Reserved.

  14. A reliable combination method to identification and typing of epidemic and endemic clones among clinical isolates of Acinetobacter baumannii.

    PubMed

    Piran, Arezoo; Shahcheraghi, Fereshteh; Solgi, Hamid; Rohani, Mahdi; Badmasti, Farzad

    2017-10-01

    The multi-drug resistant (MDR) Acinetobacter baumannii as an important nosocomial pathogen has emerged a global health concern in recent years. In this study, we applied three easier, faster, and cost-effective methods including PCR-based open reading frames (ORFs) typing, sequence typing of bla OXA-51-like and RAPD-PCR method to rapid typing of A. baumannii strains. Taken together in the present study the results of ORFs typing, PCR-sequencing of bla OXA-51-like genes and MLST sequence typing revealed there was a high prevalence (62%, 35/57) of ST2 as international and successful clone which detected among clinical isolates of multi-drug resistant A. baumannii with ORF pattern B and bla OXA-66 gene. Only 7% (4/57) of MDR isolates belonged to ST1 with ORF pattern A and bla OXA-69 gene. Interestingly, we detected singleton ST513 (32%, 18/57) that encoded bla OXA-90 and showed the ORF pattern H as previously isolated in Middle East. Moreover, our data showed RAPD-PCR method can detect divergent strains of the STs. The Cl-1, Cl-2, Cl-3, Cl-4, Cl-10, Cl-11, Cl-12, Cl-13 and Cl-14 belonged to ST2. While the Cl-6, Cl-7, Cl-8 and Cl-9 belonged to ST513. Only Cl-5 belonged to ST1. It seems that the combination of these methods have more discriminatory than any method separately and could be effectively applied to rapid detection of the clonal complex (CC) of A. baumannii strains without performing of MLST or PFGE. Copyright © 2017 Elsevier B.V. All rights reserved.

  15. Fiber type-specific analysis of AMPK isoforms in human skeletal muscle: advancement in methods via capillary nanoimmunoassay.

    PubMed

    Tobias, Irene S; Lazauskas, Kara K; Arevalo, Jose A; Bagley, James R; Brown, Lee E; Galpin, Andrew J

    2018-04-01

    Human skeletal muscle is a heterogeneous mixture of multiple fiber types (FT). Unfortunately, present methods for FT-specific study are constrained by limits of protein detection in single-fiber samples. These limitations beget compensatory resource-intensive procedures, ultimately dissuading investigators from pursuing FT-specific research. Additionally, previous studies neglected hybrid FT, confining their analyses to only pure FT. Here we present novel methods of protein detection across a wider spectrum of human skeletal muscle FT using fully automated capillary nanoimmunoassay (CNIA) technology. CNIA allowed a ~20-fold-lower limit of 5'-AMP-activated protein kinase (AMPK) detection compared with Western blotting. We then performed FT-specific assessment of AMPK expression as a proof of concept. Individual human muscle fibers were mechanically isolated, dissolved, and myosin heavy chain (MHC) fiber typed via SDS-PAGE. Single-fiber samples were combined in pairs and grouped into MHC I, MHC I/IIa, MHC IIa, and MHC IIa/IIx for expression analysis of AMPK isoforms α 1 , α 2 , β 1 , β 2 , γ 2 , and γ 3 with a tubulin loading control. Significant FT-specific differences were found for α 2 (1.7-fold higher in MHC IIa and MHC IIa/IIx vs. others), γ 2 (2.5-fold higher in MHC IIa vs. others), and γ 3 (2-fold higher in MHC IIa and 4-fold higher in MHC IIa/IIx vs. others). Development of a protocol that combines the efficient and sensitive CNIA technology with comprehensive SDS-PAGE fiber typing marks an important advancement in FT-specific research because it allows more precise study of the molecular mechanisms governing metabolism, adaptation, and regulation in human muscle. NEW & NOTEWORTHY We demonstrate the viability of applying capillary nanoimmunoassay technology to the study of fiber type-specific protein analysis in human muscle fibers. This novel technique enables a ~20-fold-lower limit of protein detection compared with traditional Western blotting

  16. Proceedings of Biological Actions of Extracellular ATP Conference Held in Philadelphia, Pennsylvania on 27-19 November 1990. (Annals of the New York Academy of Sciences. Volume 603)

    DTIC Science & Technology

    1990-12-16

    Uncomplexed with Divalent Cations Activate a Receptor Coupled to Phosphoinositidase C in iitar Cells. By J. S. DAVIDsoN, 1. WAKEFIEL, P. A. VAN DER ...selective antagonist, at least over a limited concentration range)." ’ Studies of the pharma - cological actions of isopolar phosphonate analogues of...139 VAN DER MERWE, F A, 1. K WAKEFIELD, I FINE, R, P. MILLAR & 3. S. DAVIDSON, 1989 FEltS Lell 243: 333-336. 140 HARDEN, T K, J L BOYER, It A BROWN

  17. Targeting histone abnormality in triple negative breast cancer

    DTIC Science & Technology

    2017-08-01

    ELEMENT NUMBER N/A 6. AUTHOR(S) 5d. PROJECT NUMBER N/A Yi Huang, M.D., Ph.D. 5e. TASK NUMBER N/A E -Mail:huangy2@upmc.edu 5f. WORK UNIT NUMBER...prevention. This funded Breast Cancer Breakthrough Award is initially a partnership between Dr. Yi Huang (initiating PI) and Dr. Nancy E . Davidson...partner PI). During the current funding period, Dr. Nancy E . Davidson moved to University of Washington at Seattle and transferred the Partnering PI to

  18. Assessing Patterns of Alcohol Taxes Produced by Various Types of Excise Tax Methods--A Simulation Study.

    PubMed

    Sornpaisarn, Bundit; Kaewmungkun, Chuthaporn; Rehm, Jürgen

    2015-11-01

    To examine patterns of tax burdens produced by specific, ad valorem, and various types of combination taxations. One hundred unique hypothetical alcoholic beverages were mathematically simulated based on the amount of ethanol and perceived-qualities contained. Second, beverages were assigned values of various costs and tax rates, and third, patterns of tax burden were assessed per unit of ethanol produced by each type of tax method. Different tax methods produced different tax burdens per unit of ethanol for different alcoholic beverages. The tax burden produced by the ad valorem tax resulted in a lower tax burden for low perceived-quality alcoholic beverages. The specific tax method showed the same tax burden for both low and high perceived-quality alcoholic beverages. However, high perceived-quality beverages benefited from a lower tax burden per beverage price. Lastly, the combination tax method resulted in a lower tax burden for medium perceived-quality alcoholic beverages. Under the oligopoly market, ad valorem taxation encourages consumption of low perceived-quality beverages; specific taxation encourages consumption of high perceived-quality beverages; and combination tax methods encourage consumption of medium perceived-quality beverages. © The Author 2015. Medical Council on Alcohol and Oxford University Press. All rights reserved.

  19. Effects of cooking method, cooking oil, and food type on aldehyde emissions in cooking oil fumes.

    PubMed

    Peng, Chiung-Yu; Lan, Cheng-Hang; Lin, Pei-Chen; Kuo, Yi-Chun

    2017-02-15

    Cooking oil fumes (COFs) contain a mixture of chemicals. Of all chemicals, aldehydes draw a great attention since several of them are considered carcinogenic and formation of long-chain aldehydes is related to fatty acids in cooking oils. The objectives of this research were to compare aldehyde compositions and concentrations in COFs produced by different cooking oils, cooking methods, and food types and to suggest better cooking practices. This study compared aldehydes in COFs produced using four cooking oils (palm oil, rapeseed oil, sunflower oil, and soybean oil), three cooking methods (stir frying, pan frying, and deep frying), and two foods (potato and pork loin) in a typical kitchen. Results showed the highest total aldehyde emissions in cooking methods were produced by deep frying, followed by pan frying then by stir frying. Sunflower oil had the highest emissions of total aldehydes, regardless of cooking method and food type whereas rapeseed oil and palm oil had relatively lower emissions. This study suggests that using gentle cooking methods (e.g., stir frying) and using oils low in unsaturated fatty acids (e.g., palm oil or rapeseed oil) can reduce the production of aldehydes in COFs, especially long-chain aldehydes such as hexanal and t,t-2,4-DDE. Copyright © 2016 Elsevier B.V. All rights reserved.

  20. Evaluation of a Method Using Three Genomic Guided Escherichia coli Markers for Phylogenetic Typing of E. coli Isolates of Various Genetic Backgrounds.

    PubMed

    Hamamoto, Kouta; Ueda, Shuhei; Yamamoto, Yoshimasa; Hirai, Itaru

    2015-06-01

    Genotyping and characterization of bacterial isolates are essential steps in the identification and control of antibiotic-resistant bacterial infections. Recently, one novel genotyping method using three genomic guided Escherichia coli markers (GIG-EM), dinG, tonB, and dipeptide permease (DPP), was reported. Because GIG-EM has not been fully evaluated using clinical isolates, we assessed this typing method with 72 E. coli collection of reference (ECOR) environmental E. coli reference strains and 63 E. coli isolates of various genetic backgrounds. In this study, we designated 768 bp of dinG, 745 bp of tonB, and 655 bp of DPP target sequences for use in the typing method. Concatenations of the processed marker sequences were used to draw GIG-EM phylogenetic trees. E. coli isolates with identical sequence types as identified by the conventional multilocus sequence typing (MLST) method were localized to the same branch of the GIG-EM phylogenetic tree. Sixteen clinical E. coli isolates were utilized as test isolates without prior characterization by conventional MLST and phylogenetic grouping before GIG-EM typing. Of these, 14 clinical isolates were assigned to a branch including only isolates of a pandemic clone, E. coli B2-ST131-O25b, and these results were confirmed by conventional typing methods. Our results suggested that the GIG-EM typing method and its application to phylogenetic trees might be useful tools for the molecular characterization and determination of the genetic relationships among E. coli isolates. Copyright © 2015, American Society for Microbiology. All Rights Reserved.

  1. A graphical method for identifying the six types of non-deep physiological dormancy in seeds.

    PubMed

    Soltani, E; Baskin, C C; Baskin, J M

    2017-09-01

    We present a new seed dormancy classification scheme for the non-deep level of the class physiological dormancy (PD), which contains six types. Non-deep PD is divided into two sublevels: one for seeds that exhibit a dormancy continuum (types 1, 2 and 3) and the other for those that do not exhibit a dormancy continuum (types 4, 5 and 6). Analysis of previous studies showed that different types of non-deep PD also can be identified using a graphical method. Seeds with a dormancy (D) ↔ conditional dormancy (CD) ↔ non-dormancy (ND) cycle have a low germination percentage in the early stages of CD, and during dormancy loss the germination capacity increases. However, seeds with a CD/ND (i.e. D→CD↔ND) cycle germinate to a high percentage at a narrow range of temperatures in the early stages of CD. Cardinal temperatures for seeds with either a D/ND or a CD/ND cycle change during dormancy loss: the ceiling temperature increases in seeds with Type 1, the base temperature decreases in seeds with Type 2 and the base and ceiling temperatures decrease and increase, respectively, in seeds with Type 3. Criteria for distinguishing the six types of non-deep PD and models of the temperature functions of seeds with types 1, 2 and 3 with both types of dormancy cycles are presented. The relevancy of our results to modelling the timing of weed seedling emergence is briefly discussed. © 2017 German Botanical Society and The Royal Botanical Society of the Netherlands.

  2. Frozen Elephant Trunk and Antegrade Visceral Debranching in the Surgical Treatment of Type B Aortic Dissection: An Alternative Method

    PubMed Central

    Tuncer, Altug; Akbulut, Mustafa; Adademir, Taylan; Tas, Serpil; Ak, Adnan; Arslan, Özgür; Erden, Benay; Şişmanoğlu, Mesut

    2016-01-01

    Intervention is inevitable in complicated Type B aortic dissections. Classical surgical procedures and endovascular interventions are far from ideal treatments due to their high risk of periprocedural complications and mortality. There is often a need for alternative method in cases of difficult anatomy. We present the combined use of frozen elephant trunk and antegrade visceral debranching methods in the treatment of a 54-year-old male patient with complicated Type B aortic dissection. PMID:28516092

  3. Staphylococcus aureus strains associated with food poisoning outbreaks in France: comparison of different molecular typing methods, including MLVA

    PubMed Central

    Roussel, Sophie; Felix, Benjamin; Vingadassalon, Noémie; Grout, Joël; Hennekinne, Jacques-Antoine; Guillier, Laurent; Brisabois, Anne; Auvray, Fréderic

    2015-01-01

    Staphylococcal food poisoning outbreaks (SFPOs) are frequently reported in France. However, most of them remain unconfirmed, highlighting a need for a better characterization of isolated strains. Here we analyzed the genetic diversity of 112 Staphylococcus aureus strains isolated from 76 distinct SFPOs that occurred in France over the last 30 years. We used a recently developed multiple-locus variable-number tandem-repeat analysis (MLVA) protocol and compared this method with pulsed field gel electrophoresis (PFGE), spa-typing and carriage of genes (se genes) coding for 11 staphylococcal enterotoxins (i.e., SEA, SEB, SEC, SED, SEE, SEG, SEH, SEI, SEJ, SEP, SER). The strains known to have an epidemiological association with one another had identical MLVA types, PFGE profiles, spa-types or se gene carriage. MLVA, PFGE and spa-typing divided 103 epidemiologically unrelated strains into 84, 80, and 50 types respectively demonstrating the high genetic diversity of S. aureus strains involved in SFPOs. Each MLVA type shared by more than one strain corresponded to a single spa-type except for one MLVA type represented by four strains that showed two different-but closely related-spa-types. The 87 enterotoxigenic strains were distributed across 68 distinct MLVA types that correlated all with se gene carriage except for four MLVA types. The most frequent se gene detected was sea, followed by seg and sei and the most frequently associated se genes were sea-seh and sea-sed-sej-ser. The discriminatory ability of MLVA was similar to that of PFGE and higher than that of spa-typing. This MLVA protocol was found to be compatible with high throughput analysis, and was also faster and less labor-intensive than PFGE. MLVA holds promise as a suitable method for investigating SFPOs and tracking the source of contamination in food processing facilities in real time. PMID:26441849

  4. [Clinical analysis of different root treatment methods in acute Stanford type A aortic dissection].

    PubMed

    Xue, Y X; Zhou, Q; Pan, J; Wang, Q; Cao, H L; Fan, F D; Wang, D J

    2017-04-01

    Objective: To discuss the perioperative and follow-up results of different surgical methods for acute Stanford type A aortic dissection patients and analyzed the results. Methods: The clinic data of 351 acute Stanford type A aortic dissection patients received surgical therapy at Department of Thoracic and Cardiovascular Surgery, Nanjing University Medical School Affiliated Nanjing Drum Tower Hospital from January 2008 to December 2015 were analyzed retrospectively. There were 272 male and 79 female patients, aging from 22 to 83 years with a mean age of (52±13) years. According to root size, aortic valve structure and the status of dissection involvement, these patients were devided into three major groups: 218 cases with root reconstruction using Dacron felts, 34 cases with root reconstruction concomitant with aortic valve resuspension repair and 99 cases in with Bentall procedure. Proper shape based on the status of dissection involvement of Dacron patch was cut and put between the middle and outerlayer of aorta, then inside the inner layerone band Dacron felt was sutured with the aorta and the new middle layer with Dacron patch as mentioned above. In some cases the prolapsed aortic valve was re-suspended to the aortic cusp. Clinical outcomes among the 3 procedures were compared by χ(2) test, Fisher's exact test, t test and analysis of variance. Results: Cardiopulmonary bypass, cross-clamp, and circulatory arrest times of all the patients were (250±78), (171±70) and (31±10) minutes, respectively. The 30-day mortality was 9.2%(33/351), while no difference among the 3 procedures (9.6%, 8.8% and 9.1%). In the average follow-up time of (26.0±23.0) months (range from 0.5 to 90.0 months), survival rates were similar among the 3 procedures (77.7%, 77.4% and 77.8%). Only one patient received redo Bentall procedure because of severe aortic regurgitation and dilated aortic root (diameter of 50 mm). Conclusions: The indication of root management of acute Stanford type

  5. Advances in Blood Typing.

    PubMed

    Quraishy, N; Sapatnekar, S

    The clinical importance of blood group antigens relates to their ability to evoke immune antibodies that are capable of causing hemolysis. The most important antigens for safe transfusion are ABO and D (Rh), and typing for these antigens is routinely performed for patients awaiting transfusion, prenatal patients, and blood donors. Typing for other blood group antigens, typically of the Kell, Duffy, Kidd, and MNS blood groups, is sometimes necessary, for patients who have, or are likely to develop antibodies to these antigens. The most commonly used typing method is serological typing, based on hemagglutination reactions against specific antisera. This method is generally reliable and practical for routine use, but it has certain drawbacks. In recent years, molecular typing has emerged as an alternative or supplemental typing method. It is based on detecting the polymorphisms and mutations that control the expression of blood group antigens, and using this information to predict the probable antigen type. Molecular typing methods are useful when traditional serological typing methods cannot be used, as when a patient has been transfused and the sample is contaminated with red blood cells from the transfused blood component. Moreover, molecular typing methods can precisely identify clinically significant variant antigens that cannot be distinguished by serological typing; this capability has been exploited for the resolution of typing discrepancies and shows promise for the improved transfusion management of patients with sickle cell anemia. Despite its advantages, molecular typing has certain limitations, and it should be used in conjunction with serological methods. © 2016 Elsevier Inc. All rights reserved.

  6. A simple method for MR elastography: a gradient-echo type multi-echo sequence.

    PubMed

    Numano, Tomokazu; Mizuhara, Kazuyuki; Hata, Junichi; Washio, Toshikatsu; Homma, Kazuhiro

    2015-01-01

    To demonstrate the feasibility of a novel MR elastography (MRE) technique based on a conventional gradient-echo type multi-echo MR sequence which does not need additional bipolar magnetic field gradients (motion encoding gradient: MEG), yet is sensitive to vibration. In a gradient-echo type multi-echo MR sequence, several images are produced from each echo of the train with different echo times (TEs). If these echoes are synchronized with the vibration, each readout's gradient lobes achieve a MEG-like effect, and the later generated echo causes a greater MEG-like effect. The sequence was tested for the tissue-mimicking agarose gel phantoms and the psoas major muscles of healthy volunteers. It was confirmed that the readout gradient lobes caused an MEG-like effect and the later TE images had higher sensitivity to vibrations. The magnitude image of later generated echo suffered the T2 decay and the susceptibility artifacts, but the wave image and elastogram of later generated echo were unaffected by these effects. In in vivo experiments, this method was able to measure the mean shear modulus of the psoas major muscle. From the results of phantom experiments and volunteer studies, it was shown that this method has clinical application potential. Copyright © 2014 Elsevier Inc. All rights reserved.

  7. Carotenoid profiling from 27 types of paprika (Capsicum annuum L.) with different colors, shapes, and cultivation methods.

    PubMed

    Kim, Ji-Sun; An, Chul Geon; Park, Jong-Suk; Lim, Yong Pyo; Kim, Suna

    2016-06-15

    In this study, we investigated carotenoid profiles and contents from 27 types of paprika with different colors (red, orange, and yellow), shapes (blocky and conical), and cultivation methods (soil and soilless). We simultaneously analyzed 12 kinds of carotenoids using UPLC equipped with an HSS T3 column for 30 min, and we identified six kinds of carotenoids in red paprika and nine types in orange and yellow paprika. Zeaxanthin concentrations in orange paprika were in the range of 85.06±23.37-151.39±5.94 mg/100 g dry weight (dw), which shows that orange paprika is a great source of zeaxanthin. Generally, red paprika is a great source of capsanthin. However, a new cultivar, 'Mini Goggal Red', contained large amounts of zeaxanthin (121.41±30.10 mg/100 g dw) even though its visible color is red. This is very meaningful considering that consumers have a preference for red color and the potent functional value of zeaxanthin. Carotenoid profiles and concentrations in blocky and conical type paprika were not significantly different in red paprika except the 'Mini Goggal Red' cultivar and yellow paprika. Blocky type orange paprika contains plenty of zeaxanthin, unlike conical type orange paprika. Three new cultivars of the conical type were cultivated in both soil culture and soilless culture in the same province, and carotenoid profiles and concentrations were similar, showing that both cultivations methods can be used. Copyright © 2016. Published by Elsevier Ltd.

  8. Baryon axial charges from chirally improved fermions - first results

    NASA Astrophysics Data System (ADS)

    Engel, G.; Gattringer, C.; Glozman, L. Y.; Lang, C. B.; Limmer, M.; Mohler, D.; Schäfer, A.

    We present first results from dynamical Chirally Improved (CI) fermion simulations for the axial charge $G_A$ of various hadrons. We work with 16^3x32 lattices of spatial extent 2.4 fm and use the variational method with a suitable basis of Jacobi-smeared interpolators to suppress contaminations from excited states.

  9. Automatic recognition of coronal type II radio bursts: The ARBIS 2 method and first observations

    NASA Astrophysics Data System (ADS)

    Lobzin, Vasili; Cairns, Iver; Robinson, Peter; Steward, Graham; Patterson, Garth

    Major space weather events such as solar flares and coronal mass ejections are usually accompa-nied by solar radio bursts, which can potentially be used for real-time space weather forecasts. Type II radio bursts are produced near the local plasma frequency and its harmonic by fast electrons accelerated by a shock wave moving through the corona and solar wind with a typi-cal speed of 1000 km s-1 . The coronal bursts have dynamic spectra with frequency gradually falling with time and durations of several minutes. We present a new method developed to de-tect type II coronal radio bursts automatically and describe its implementation in an extended Automated Radio Burst Identification System (ARBIS 2). Preliminary tests of the method with spectra obtained in 2002 show that the performance of the current implementation is quite high, ˜ 80%, while the probability of false positives is reasonably low, with one false positive per 100-200 hr for high solar activity and less than one false event per 10000 hr for low solar activity periods. The first automatically detected coronal type II radio bursts are also presented. ARBIS 2 is now operational with IPS Radio and Space Services, providing email alerts and event lists internationally.

  10. Differential effects of plant ontogeny and damage type on phloem and foliage monoterpenes in jack pine (Pinus banksiana).

    PubMed

    Erbilgin, Nadir; Colgan, L Jessie

    2012-08-01

    Coniferous trees have both constitutive and inducible defences that deter or kill herbivores and pathogens. We investigated constitutive and induced monoterpene responses of jack pine (Pinus banksiana Lamb.) to a number of damage types: a fungal associate of the mountain pine beetle (Dendroctonus ponderosae Hopkins), Grosmannia clavigera (Robinson-Jeffrey & R.W. Davidson); two phytohormones, methyl jasmonate (MJ) and methyl salicylate (MS); simulated herbivory; and mechanical wounding. We only included the fungal, MJ and mechanical wounding treatments in the field experiments while all treatments were part of the greenhouse studies. We focused on both constitutive and induced responses between juvenile and mature jack pine trees and differences in defences between phloem and needles. We found that phytohormone applications and fungal inoculation resulted in the greatest increase in monoterpenes in both juvenile and mature trees. Additionally, damage types differentially affected the proportions of individual monoterpenes: MJ-treated mature trees had higher myrcene and β-pinene than fungal-inoculated mature trees, while needles of juveniles inoculated with the fungus contained higher limonene than MJ- or MS-treated juveniles. Although the constitutive monoterpenes were higher in the phloem of juveniles than mature jack pine trees, the phloem of mature trees had a much higher magnitude of induction. Further, induced monoterpene concentrations in juveniles were higher in phloem than in needles. There was no difference in monoterpene concentration between phytohormone applications and G. clavigera inoculation in mature trees, while in juvenile trees MJ was different from both G. clavigera and simulated herbivory in needle monoterpenes, but there was no difference between phytohormone applications and simulated herbivory in the phloem.

  11. Discrete element method for emergency flow of pedestrian in S-type corridor.

    PubMed

    Song, Gyeongwon; Park, Junyoung

    2014-10-01

    Pedestrian flow in curved corridor should be modeled before design because this type of corridor can be most dangerous part during emergency evacuation. In this study, this flow is analyzed by Discrete Element Method with psychological effects. As the turning slope of corridor increases, the evacuation time is linearly increases. However, in the view of crashed death accident, the case with 90 degree turning slope can be dangerous because there are 3 dangerous points. To solve this matter, the pedestrian gathering together in curved part should be dispersed.

  12. Rapid calculation method for Frenkel-type two-exciton states in one to three dimensions

    NASA Astrophysics Data System (ADS)

    Ajiki, Hiroshi

    2014-07-01

    Biexciton and two-exciton dissociated states of Frenkel-type excitons are well described by a tight-binding model with a nearest-neighbor approximation. Such two-exciton states in a finite-size lattice are usually calculated by numerical diagonalization of the Hamiltonian, which requires an increasing amount of computational time and memory as the lattice size increases. I develop here a rapid, memory-saving method to calculate the energies and wave functions of two-exciton states by employing a bisection method. In addition, an attractive interaction between two excitons in the tight-binding model can be obtained directly so that the biexciton energy agrees with the observed energy, without the need for the trial-and-error procedure implemented in the numerical diagonalization method.

  13. A new method for meniscus repair using type I collagen scaffold and infrapatellar fat pad.

    PubMed

    Oda, Shuhei; Otsuki, Shuhei; Kurokawa, Yoshitaka; Hoshiyama, Yoshiaki; Nakajima, Mikio; Neo, Masashi

    2015-05-01

    The aim of this study was to investigate a new method for meniscal repair by combinative transplantation with type I collagen scaffold and infrapatellar fat pad. Two-mm cylindrical defects at the anterior part of bilateral medial menisci were prepared in nine Japanese white rabbits. The 18 knees were equally divided into three groups: I, no treatment; II, collagen scaffold transplantation; and III, collagen scaffold and infrapatellar fat pad transplantation. Another three rabbits (six knees) underwent sham surgery and served as controls. Rabbits were sacrificed at eight weeks after transplantation. Surface area of the medial meniscus was evaluated using macrophotographs. Ishida score for meniscal regeneration was used for assessment. To evaluate the composition of regenerated tissue, immunohistochemistry was analyzed with anti-type I and anti-type II collagen antibodies, and anti-Ki67 antibody. To investigate the effects of collagen scaffold on human meniscus, cells were isolated from human meniscus and infrapatellar fat pad, and cultured with collagen scaffold for three weeks. After that, gene expression was evaluated by using quantitative real-time polymerase chain reaction. In group I, the meniscus shrank anterior to posterior, and the surface area was significantly less than that of normal meniscus. However, the surface area was maintained in group III. Ishida score and Ki67-positive cell ratio in group III were significantly higher than that in any other group, and staining with type I and type II collagen was similar to that of the control. Expression of matrix metalloproteinase was significantly lower in cocultures of collagen scaffold, meniscus cell, and infrapatellar fat pad cell than in monocultured meniscus cell, and expression of interleukin-1β was not increased. This new method for meniscal repair by combinative transplantation with type I collagen scaffold and infrapatellar fat pad showed meniscal regeneration and potential for suppressing

  14. A mathematical model of microbial enhanced oil recovery (MEOR) method for mixed type rock

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sitnikov, A.A.; Eremin, N.A.; Ibattulin, R.R.

    1994-12-31

    This paper deals with the microbial enhanced oil recovery method. It covers: (1) Mechanism of microbial influence on the reservoir was analyzed; (2) The main groups of metabolites affected by the hydrodynamic characteristics of the reservoir were determined; (3) The criterions of use of microbial influence method on the reservoir are defined. The mathematical model of microbial influence on the reservoir was made on this basis. The injection of molasse water solution with Clostridium bacterias into the mixed type of rock was used in this model. And the results of calculations were compared with experimental data.

  15. Versatile methods for synthesizing organic acid salts of quaternary berberine-type alkaloids as anti-ulcerative colitis agents.

    PubMed

    Zhang, Zhi-Hui; Li, Jing; Zhang, Hai-Jing; Deng, An-Jun; Wu, Lian-Qiu; Li, Zhi-Hong; Song, Hong-Rui; Wang, Wen-Jie; Qin, Hai-Lin

    2016-06-01

    Two versatile methods to synthesize kinds of organic acid salts of quaternary berberine-type alkaloids were investigated in order to determine which is more efficient to improve the liposolubility of the target compounds and to explore the efficacy of the target compounds as anti-ulcerative colitis (UC) agents. Overall evaluation according to the reaction results and yields of the final products indicated that the synthetic method using tertiary (±)-8-acylmethyldihydroberberine-type alkaloids as key intermediates is superior to that of using tertiary dihydroberberine-type alkaloids as intermediates. Ten target compounds were synthesized using quaternary berberine chloride and quaternary coptisine chloride as starting materials, respectively, and the anti-UC activity of some target compounds was evaluated in an in vitro x-box-binding protein 1 (XBP1) transcriptional activity assay using dual luciferase reporter detection. At 10 μM, the tested compounds were found to activate the transcription of XBP1 target at almost the same level as that of quaternary coptisine chloride. The synthesized target compounds were also found to share higher liposolubility than the inorganic acid salts of quaternary berberine-type alkaloid.

  16. 49 CFR Appendix D to Part 173 - Test Methods for Dynamite (Explosive, Blasting, Type A)

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 2 2014-10-01 2014-10-01 false Test Methods for Dynamite (Explosive, Blasting, Type A) D Appendix D to Part 173 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HAZARDOUS MATERIALS REGULATIONS SHIPPERS-GENERAL REQUIREMENTS FOR...

  17. Pharmacy diabetes care program: analysis of two screening methods for undiagnosed type 2 diabetes in Australian community pharmacy.

    PubMed

    Krass, I; Mitchell, B; Clarke, P; Brillant, M; Dienaar, R; Hughes, J; Lau, P; Peterson, G; Stewart, K; Taylor, S; Wilkinson, J; Armour, C

    2007-03-01

    To compare the efficacy and cost-effectiveness of two methods of screening for undiagnosed type 2 diabetes in Australian community pharmacy. A random sample of 30 pharmacies were allocated into two groups: (i) tick test only (TTO); or (ii) sequential screening (SS) method. Both methods used the same initial risk assessment for type 2 diabetes. Subjects with one or more risk factors in the TTO group were offered a referral to their general practitioner (GP). Under the SS method, patients with risk factors were offered a capillary blood glucose test and those identified as being at risk referred to a GP. The effectiveness and cost-effectiveness of these approaches was assessed. A total of 1286 people were screened over a period of 3 months. The rate of diagnosis of diabetes was significantly higher for SS compared with the TTO method (1.7% versus 0.2%; p=0.008). The SS method resulted in fewer referrals to the GP and a higher uptake of referrals than the TTO method and so was the more cost-effective screening method. SS is the superior method from a cost and efficacy perspective. It should be considered as the preferred option for screening by community based pharmacists in Australia.

  18. Robust Multigrid Smoothers for Three Dimensional Elliptic Equations with Strong Anisotropies

    NASA Technical Reports Server (NTRS)

    Llorente, Ignacio M.; Melson, N. Duane

    1998-01-01

    We discuss the behavior of several plane relaxation methods as multigrid smoothers for the solution of a discrete anisotropic elliptic model problem on cell-centered grids. The methods compared are plane Jacobi with damping, plane Jacobi with partial damping, plane Gauss-Seidel, plane zebra Gauss-Seidel, and line Gauss-Seidel. Based on numerical experiments and local mode analysis, we compare the smoothing factor of the different methods in the presence of strong anisotropies. A four-color Gauss-Seidel method is found to have the best numerical and architectural properties of the methods considered in the present work. Although alternating direction plane relaxation schemes are simpler and more robust than other approaches, they are not currently used in industrial and production codes because they require the solution of a two-dimensional problem for each plane in each direction. We verify the theoretical predictions of Thole and Trottenberg that an exact solution of each plane is not necessary and that a single two-dimensional multigrid cycle gives the same result as an exact solution, in much less execution time. Parallelization of the two-dimensional multigrid cycles, the kernel of the three-dimensional implicit solver, is also discussed. Alternating-plane smoothers are found to be highly efficient multigrid smoothers for anisotropic elliptic problems.

  19. Analysis of focusing error signals by differential astigmatic method under off-center tracking in the land-groove-type optical disk

    NASA Astrophysics Data System (ADS)

    Shinoda, Masahisa; Nakatani, Hidehiko

    2015-04-01

    We theoretically calculate the behavior of the focusing error signal in the land-groove-type optical disk when the objective lens traverses on out of the radius of the optical disk. The differential astigmatic method is employed instead of the conventional astigmatic method for generating the focusing error signals. The signal behaviors are compared and analyzed in terms of the gain difference of the slope sensitivity of the focusing error signals from the land and the groove. In our calculation, the format of digital versatile disc-random access memory (DVD-RAM) is adopted as the land-groove-type optical disk model, and advantageous conditions for suppressing the gain difference are investigated. The calculation method and results described in this paper will be reflected in the next generation land-groove-type optical disks.

  20. Development of an irradiation method with lateral modulation of SOBP width using a cone-type filter for carbon ion beams.

    PubMed

    Ishizaki, Azusa; Ishii, Keizo; Kanematsu, Nobuyuki; Kanai, Tatsuaki; Yonai, Shunsuke; Kase, Yuki; Takei, Yuka; Komori, Masataka

    2009-06-01

    Passive irradiation methods deliver an extra dose to normal tissues upstream of the target tumor, while in dynamic irradiation methods, interplay effects between dynamic beam delivery and target motion induced by breathing or respiration distort the dose distributions. To solve the problems of those two irradiation methods, the authors have developed a new method that laterally modulates the spread-out Bragg peak (SOBP) width. By reducing scanning in the depth direction, they expect to reduce the interplay effects. They have examined this new irradiation method experimentally. In this system, they used a cone-type filter that consisted of 400 cones in a grid of 20 cones by 20 cones. There were five kinds of cones with different SOBP widths arranged on the frame two dimensionally to realize lateral SOBP modulation. To reduce the number of steps of cones, they used a wheel-type filter to make minipeaks. The scanning intensity was modulated for each SOBP width with a pair of scanning magnets. In this experiment, a stepwise dose distribution and spherical dose distribution of 60 mm in diameter were formed. The nonflatness of the stepwise dose distribution was 5.7% and that of the spherical dose distribution was 3.8%. A 2 mm misalignment of the cone-type filter resulted in a nonflatness of more than 5%. Lateral SOBP modulation with a cone-type filter and a scanned carbon ion beam successfully formed conformal dose distribution with nonflatness of 3.8% for the spherical case. The cone-type filter had to be set to within 1 mm accuracy to maintain nonflatness within 5%. This method will be useful to treat targets moving during breathing and targets in proximity to important organs.

  1. Power Spectral Density Error Analysis of Spectral Subtraction Type of Speech Enhancement Methods

    NASA Astrophysics Data System (ADS)

    Händel, Peter

    2006-12-01

    A theoretical framework for analysis of speech enhancement algorithms is introduced for performance assessment of spectral subtraction type of methods. The quality of the enhanced speech is related to physical quantities of the speech and noise (such as stationarity time and spectral flatness), as well as to design variables of the noise suppressor. The derived theoretical results are compared with the outcome of subjective listening tests as well as successful design strategies, performed by independent research groups.

  2. A modified weighted function method for parameter estimation of Pearson type three distribution

    NASA Astrophysics Data System (ADS)

    Liang, Zhongmin; Hu, Yiming; Li, Binquan; Yu, Zhongbo

    2014-04-01

    In this paper, an unconventional method called Modified Weighted Function (MWF) is presented for the conventional moment estimation of a probability distribution function. The aim of MWF is to estimate the coefficient of variation (CV) and coefficient of skewness (CS) from the original higher moment computations to the first-order moment calculations. The estimators for CV and CS of Pearson type three distribution function (PE3) were derived by weighting the moments of the distribution with two weight functions, which were constructed by combining two negative exponential-type functions. The selection of these weight functions was based on two considerations: (1) to relate weight functions to sample size in order to reflect the relationship between the quantity of sample information and the role of weight function and (2) to allocate more weights to data close to medium-tail positions in a sample series ranked in an ascending order. A Monte-Carlo experiment was conducted to simulate a large number of samples upon which statistical properties of MWF were investigated. For the PE3 parent distribution, results of MWF were compared to those of the original Weighted Function (WF) and Linear Moments (L-M). The results indicate that MWF was superior to WF and slightly better than L-M, in terms of statistical unbiasness and effectiveness. In addition, the robustness of MWF, WF, and L-M were compared by designing the Monte-Carlo experiment that samples are obtained from Log-Pearson type three distribution (LPE3), three parameter Log-Normal distribution (LN3), and Generalized Extreme Value distribution (GEV), respectively, but all used as samples from the PE3 distribution. The results show that in terms of statistical unbiasness, no one method possesses the absolutely overwhelming advantage among MWF, WF, and L-M, while in terms of statistical effectiveness, the MWF is superior to WF and L-M.

  3. Portfolio Optimization with Stochastic Dividends and Stochastic Volatility

    ERIC Educational Resources Information Center

    Varga, Katherine Yvonne

    2015-01-01

    We consider an optimal investment-consumption portfolio optimization model in which an investor receives stochastic dividends. As a first problem, we allow the drift of stock price to be a bounded function. Next, we consider a stochastic volatility model. In each problem, we use the dynamic programming method to derive the Hamilton-Jacobi-Bellman…

  4. System and method employing a self-organizing map load feature database to identify electric load types of different electric loads

    DOEpatents

    Lu, Bin; Harley, Ronald G.; Du, Liang; Yang, Yi; Sharma, Santosh K.; Zambare, Prachi; Madane, Mayura A.

    2014-06-17

    A method identifies electric load types of a plurality of different electric loads. The method includes providing a self-organizing map load feature database of a plurality of different electric load types and a plurality of neurons, each of the load types corresponding to a number of the neurons; employing a weight vector for each of the neurons; sensing a voltage signal and a current signal for each of the loads; determining a load feature vector including at least four different load features from the sensed voltage signal and the sensed current signal for a corresponding one of the loads; and identifying by a processor one of the load types by relating the load feature vector to the neurons of the database by identifying the weight vector of one of the neurons corresponding to the one of the load types that is a minimal distance to the load feature vector.

  5. A New Method for the Quick Determination of S-Type and P-Type Habitable Zones in Binary Systems

    NASA Astrophysics Data System (ADS)

    Wang, Zhaopeng; Cuntz, Manfred

    2017-01-01

    More than 3500 exoplanets have been confirmed nowadays, including a very large number of planets discovered by the Kepler mission. Additional exoplanets are expected to be found by ongoing missions as, e.g., K2 as well as future missions such as TESS. Exoplanets, especially terrestrial planets, located in stellar habitable zones are drawing great attention from the community and the public at large due to their potential for hosting alien life - a prospect that makes the adequate determination of stellar habitable zones an important goal of exoplanetary research. In the local Galactic neighborhood, binary systems occur relatively frequently. Thus, it is the aim of my presentation to offer a method for the quick determination for the existence of habitable zones in binaries. Therefore, fitting formulas for binary habitable zones regarding both S-type and P-type star-planet configurations are provided. Based on previous work in the literature, a joint constraint regarding radiative habitable zones and planetary orbital stability limits is used. Models of stellar habitable zones utilize updated computations for planetary climate models as given by Kopparapu et al. (2013, 2014) [ApJ 765, 131; ApJL 787, L29]. Cases studies showing the quality of the fit formulas, as well as applications to observed systems, are presented as well.

  6. Practical Thermal Evaluation Methods For HAC Fire Analysis In Type B Radiaoactive Material (RAM) Packages

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Abramczyk, Glenn; Hensel, Stephen J; Gupta, Narendra K.

    Title 10 of the United States Code of Federal Regulations Part 71 for the Nuclear Regulatory Commission (10 CFR Part 71.73) requires that Type B radioactive material (RAM) packages satisfy certain Hypothetical Accident Conditions (HAC) thermal design requirements to ensure package safety during accidental fire conditions. Compliance with thermal design requirements can be met by prototype tests, analyses only or a combination of tests and analyses. Normally, it is impractical to meet all the HAC using tests only and the analytical methods are too complex due to the multi-physics non-linear nature of the fire event. Therefore, a combination of testsmore » and thermal analyses methods using commercial heat transfer software are used to meet the necessary design requirements. The authors, along with his other colleagues at Savannah River National Laboratory in Aiken, SC, USA, have successfully used this 'tests and analyses' approach in the design and certification of several United States' DOE/NNSA certified packages, e.g. 9975, 9977, 9978, 9979, H1700, and Bulk Tritium Shipping Package (BTSP). This paper will describe these methods and it is hoped that the RAM Type B package designers and analysts can use them for their applications.« less

  7. Unaware Memory in Hypothesis Generation Tasks

    DTIC Science & Technology

    1986-12-01

    have been offered within the context of Tulving’s (1972) distinction between episodic and semantic memory systems (e.g., see Jacoby & - Witherspoon...in this direction (see Tulving, 1985) raise the possibility that neither episodic nor semantic memory systems can account for the type of unaware...material: Interactions with " episodic " and " semantic " memory . Conitive Psycholozv, 12, 227-251. Kolers, P. A. (1976). Reading a year later. Journal o

  8. Application of Two-Parameter Stabilizing Functions in Solving a Convolution-Type Integral Equation by Regularization Method

    NASA Astrophysics Data System (ADS)

    Maslakov, M. L.

    2018-04-01

    This paper examines the solution of convolution-type integral equations of the first kind by applying the Tikhonov regularization method with two-parameter stabilizing functions. The class of stabilizing functions is expanded in order to improve the accuracy of the resulting solution. The features of the problem formulation for identification and adaptive signal correction are described. A method for choosing regularization parameters in problems of identification and adaptive signal correction is suggested.

  9. Development of a molecular method for the typing of Brettanomyces bruxellensis (Dekkera bruxellensis) at the strain level.

    PubMed

    Miot-Sertier, C; Lonvaud-Funel, A

    2007-02-01

    In recent years, Brettanomyces/Dekkera bruxellensis has caused increasingly severe quality problems in the wine industry. A typing method at the strain level is needed for a better knowledge of the dispersion and the dynamics of these yeasts from grape to wine. Three molecular tools, namely random-amplified polymorphic DNA, PCR fingerprinting with microsatellite oligonucleotide primers and SAU-PCR, were explored for their relevance to typing strains of Brettanomyces bruxellensis. The results indicated that discrimination of each individual strain was not possible with a single PCR typing technique. We described a typing method for B. bruxellensis based on restriction enzyme analysis and pulse field gel electrophoresis (REA-PFGE). Results showed that electrophoretic profiles were reproducible and specific for each strain under study. Consequently, REA-PFGE should be considered for the discrimination of B. bruxellensis strains. This technique allowed a fine discrimination of B. bruxellensis, as strains were identified by a particular profile. This study constitutes a prerequisite for accurate and appropriate investigations on the diversity of strains throughout the winemaking and ageing process. Such studies will probably give clearer and more up-to-date information on the origin of the presence of Brettanomyces in wine after vinification when they are latent spoilage agents.

  10. Phene Plate (PhP) biochemical fingerprinting. A screening method for epidemiological typing of enterococcal isolates.

    PubMed

    Saeedi, B; Tärnberg, M; Gill, H; Hällgren, A; Jonasson, J; Nilsson, L E; Isaksson, B; Kühn, I; Hanberger, H

    2005-09-01

    Pulsed-field gel electrophoresis (PFGE) is currently considered the gold standard for genotyping of enterococci. However, PFGE is both expensive and time-consuming. The purpose of this study was to investigate whether the PhP system can be used as a reliable clinical screening method for detection of genetically related isolates of enterococci. If so, it should be possible to minimize the number of isolates subjected to PFGE typing, which would save time and money. Ninety-nine clinical enterococcal isolates were analysed by PhP (similarity levels 0.90-0.975) and PFGE (similarity levels < or =3 and < or =6 bands) and all possible pairs of isolates were cross-classified as matched or mismatched. We found that the probability that a pair of isolates (A and B) belonging to the same type according to PhP also belong to the same cluster according to PFGE, i.e. p(A(PFGE)=B(PFGE) * A(PhP)=B(PhP)), and the probability that a pair of isolates of different types according to PhP also belong to different clusters according to PFGE, i.e. p(A(PFGE) not equalB(PFGE) * A(PhP) not equalB(PhP)), was relatively high for E. faecalis (0.86 and 0.96, respectively), but was lower for E. faecium (0.51 and 0.77, respectively). The concordance which shows the probability that PhP and PFGE agree on match or mismatch was 86%-93% for E. faecalis and 54%-66% for E. faecium, which indicates that the PhP method may be useful for epidemiological typing of E. faecalis in the current settings but not for E. faecium.

  11. Novel Method for Differentiating Histological Types of Gastric Adenocarcinoma by Using Confocal Raman Microspectroscopy

    PubMed Central

    Hsu, Chih-Wei; Huang, Chia-Chi; Sheu, Jeng-Horng; Lin, Chia-Wen; Lin, Lien-Fu; Jin, Jong-Shiaw; Chau, Lai-Kwan; Chen, Wenlung

    2016-01-01

    Gastric adenocarcinoma, a single heterogeneous disease with multiple epidemiological and histopathological characteristics, accounts for approximately 10% of cancers worldwide. It is categorized into four histological types: papillary adenocarcinoma (PAC), tubular adenocarcinoma (TAC), mucinous adenocarcinoma (MAC), and signet ring cell adenocarcinoma (SRC). Effective differentiation of the four types of adenocarcinoma will greatly improve the treatment of gastric adenocarcinoma to increase its five-year survival rate. We reported here the differentiation of the four histological types of gastric adenocarcinoma from the molecularly structural viewpoint of confocal Raman microspectroscopy. In total, 79 patients underwent laparoscopic or open radical gastrectomy during 2008–2011: 21 for signet ring cell carcinoma, 21 for tubular adenocarcinoma, 14 for papillary adenocarcinoma, 6 for mucinous carcinoma, and 17 for normal gastric mucosas obtained from patients underwent operation for other benign lesions. Clinical data were retrospectively reviewed from medical charts, and Raman data were processed and analyzed by using principal component analysis (PCA) and linear discriminant analysis (LDA). Two-dimensional plots of PCA and LDA clearly demonstrated that the four histological types of gastric adenocarcinoma could be differentiated, and confocal Raman microspectroscopy provides potentially a rapid and effective method for differentiating SRC and MAC from TAC or PAC. PMID:27472385

  12. Kinetic properties of wild-type and altered recombinant amidases by the use of ion-selective electrode assay method.

    PubMed

    Martins, S; Karmali, A; Serralheiro, M L

    2006-08-15

    A novel assay method was investigated for wild-type and recombinant mutant amidases (EC 3.5.1.4) from Pseudomonas aeruginosa by ammonium ion-selective electrode (ISE). The initial velocity is proportional to the enzyme concentration by using the wild-type enzyme. The specific activities of the purified amidase were found to be 88.2 and 104.2 U mg protein(-1) for the linked assay and ISE methods, respectively. The kinetic constants--Vmax, Km, and Kcat--determined by Michaelis-Menten plot were 101.13 U mg protein(-1), 1.12x10(-2) M, and 64.04 s(-1), respectively, for acrylamide as the substrate. On the other hand, the lower limit of detection and range of linearity of enzyme concentration were found to be 10.8 and 10.8 to 500 ng, respectively, for the linked assay method and 15.0 and 15.0 to 15,000 ng, respectively, for the ISE method. Hydroxylamine was found to act as an uncompetitive activator of hydrolysis reaction catalyzed by amidase given that there is an increase in Vmax and Km when acetamide was used as the substrate. However, the effect of hydroxylamine on the hydrolysis reaction was dependent on the type of amidase and substrate involved in the reaction mixture. The degrees of activation (epsilon(a)) of the wild-type and mutant (T103I and C91A) enzymes were found to be 2.54, 12.63, and 4.33, respectively, for acetamide as the substrate. However, hydroxylamine did not activate the reaction catalyzed by wild-type and altered (C91A and W138G) amidases by using acrylamide and acetamide, respectively, as the substrate. The activating effect of hydroxylamine on the hydrolysis of acetamide, acrylamide, and p-nitrophenylacetamide can be explained by the fact that additional formation of ammonium ions occurred due to the transferase activity of amidases. However, the activating effect of hydroxylamine on the hydrolysis of p-nitroacetanilide may be due to a change in conformation of enzyme molecule. Therefore, the use of ISE permitted the study of the kinetic

  13. Numerical methods of solving a system of multi-dimensional nonlinear equations of the diffusion type

    NASA Technical Reports Server (NTRS)

    Agapov, A. V.; Kolosov, B. I.

    1979-01-01

    The principles of conservation and stability of difference schemes achieved using the iteration control method were examined. For the schemes obtained of the predictor-corrector type, the conversion was proved for the control sequences of approximate solutions to the precise solutions in the Sobolev metrics. Algorithms were developed for reducing the differential problem to integral relationships, whose solution methods are known, were designed. The algorithms for the problem solution are classified depending on the non-linearity of the diffusion coefficients, and practical recommendations for their effective use are given.

  14. Approximation properties of Fejér- and de la Valleé-Poussin-type means for partial sums of a special series in the system \\{\\sin x\\sin kx\\}_{k=1}^\\infty

    NASA Astrophysics Data System (ADS)

    Sharapudinov, I. I.

    2015-04-01

    This paper is concerned with series of the form \\displaystyle Φ(θ)=A_Φ(θ)+\\sinθ\\sumk=1^∞\\varphi_k\\sin kθ, where Φ(θ) is an even 2π-periodic function with finite values Φ(0) and Φ(π), \\displaystyle A_Φ(θ)=\\frac{Φ(0)+Φ(π)}{2}+\\frac{Φ(0)-Φ(π)}{2}\\cosθ,\\qquad\\varphi(θ)=Φ(θ)-A_Φ(θ), \\displaystyle \\varphi_k=\\frac{2}π\\int_0^π\\varphi(t)\\frac{\\sin kt}{\\sin t} dt. Series of this type appear as a particular case of more general special series in ultraspherical Jacobi polynomials, which were first introduced and studied by the author. Partial sums of the form \\Pi_n(Φ)=\\Pi_n(Φ,θ)=A_Φ(θ)+\\sinθ\\sumk=1n-1\\varphi_k\\sin kθ are shown to have a number of important properties, which give them an advantage over trigonometric Fourier sums of the form S_n(Φ,θ)=\\frac{a_0}{2}+\\sumk=1^na_k\\cos kθ. Approximation properties of Fejér- and de la Valleé-Poussin-type means for the partial sums \\Pi_n(Φ,θ) are studied. Bibliography: 7 titles.

  15. New exact solutions of the Tzitzéica-type equations in non-linear optics using the expa function method

    NASA Astrophysics Data System (ADS)

    Hosseini, K.; Ayati, Z.; Ansari, R.

    2018-04-01

    One specific class of non-linear evolution equations, known as the Tzitzéica-type equations, has received great attention from a group of researchers involved in non-linear science. In this article, new exact solutions of the Tzitzéica-type equations arising in non-linear optics, including the Tzitzéica, Dodd-Bullough-Mikhailov and Tzitzéica-Dodd-Bullough equations, are obtained using the expa function method. The integration technique actually suggests a useful and reliable method to extract new exact solutions of a wide range of non-linear evolution equations.

  16. An advanced method for classifying atmospheric circulation types based on prototypes connectivity graph

    NASA Astrophysics Data System (ADS)

    Zagouras, Athanassios; Argiriou, Athanassios A.; Flocas, Helena A.; Economou, George; Fotopoulos, Spiros

    2012-11-01

    Classification of weather maps at various isobaric levels as a methodological tool is used in several problems related to meteorology, climatology, atmospheric pollution and to other fields for many years. Initially the classification was performed manually. The criteria used by the person performing the classification are features of isobars or isopleths of geopotential height, depending on the type of maps to be classified. Although manual classifications integrate the perceptual experience and other unquantifiable qualities of the meteorology specialists involved, these are typically subjective and time consuming. Furthermore, during the last years different approaches of automated methods for atmospheric circulation classification have been proposed, which present automated and so-called objective classifications. In this paper a new method of atmospheric circulation classification of isobaric maps is presented. The method is based on graph theory. It starts with an intelligent prototype selection using an over-partitioning mode of fuzzy c-means (FCM) algorithm, proceeds to a graph formulation for the entire dataset and produces the clusters based on the contemporary dominant sets clustering method. Graph theory is a novel mathematical approach, allowing a more efficient representation of spatially correlated data, compared to the classical Euclidian space representation approaches, used in conventional classification methods. The method has been applied to the classification of 850 hPa atmospheric circulation over the Eastern Mediterranean. The evaluation of the automated methods is performed by statistical indexes; results indicate that the classification is adequately comparable with other state-of-the-art automated map classification methods, for a variable number of clusters.

  17. Effects of categorization method, regression type, and variable distribution on the inflation of Type-I error rate when categorizing a confounding variable.

    PubMed

    Barnwell-Ménard, Jean-Louis; Li, Qing; Cohen, Alan A

    2015-03-15

    The loss of signal associated with categorizing a continuous variable is well known, and previous studies have demonstrated that this can lead to an inflation of Type-I error when the categorized variable is a confounder in a regression analysis estimating the effect of an exposure on an outcome. However, it is not known how the Type-I error may vary under different circumstances, including logistic versus linear regression, different distributions of the confounder, and different categorization methods. Here, we analytically quantified the effect of categorization and then performed a series of 9600 Monte Carlo simulations to estimate the Type-I error inflation associated with categorization of a confounder under different regression scenarios. We show that Type-I error is unacceptably high (>10% in most scenarios and often 100%). The only exception was when the variable categorized was a continuous mixture proxy for a genuinely dichotomous latent variable, where both the continuous proxy and the categorized variable are error-ridden proxies for the dichotomous latent variable. As expected, error inflation was also higher with larger sample size, fewer categories, and stronger associations between the confounder and the exposure or outcome. We provide online tools that can help researchers estimate the potential error inflation and understand how serious a problem this is. Copyright © 2014 John Wiley & Sons, Ltd.

  18. A Comprehensive Analytical Solution of the Nonlinear Pendulum

    ERIC Educational Resources Information Center

    Ochs, Karlheinz

    2011-01-01

    In this paper, an analytical solution for the differential equation of the simple but nonlinear pendulum is derived. This solution is valid for any time and is not limited to any special initial instance or initial values. Moreover, this solution holds if the pendulum swings over or not. The method of approach is based on Jacobi elliptic functions…

  19. Spectral element multigrid. Part 2: Theoretical justification

    NASA Technical Reports Server (NTRS)

    Maday, Yvon; Munoz, Rafael

    1988-01-01

    A multigrid algorithm is analyzed which is used for solving iteratively the algebraic system resulting from tha approximation of a second order problem by spectral or spectral element methods. The analysis, performed here in the one dimensional case, justifies the good smoothing properties of the Jacobi preconditioner that was presented in Part 1 of this paper.

  20. Fermionic Tunneling Effect and Hawking Radiation in a Non Commutative FRW Universe

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bouhalouf, H.; Aissaoui, H.; Mebarki, N.

    2010-10-31

    The formalism of a non commutative gauge gravity is applied to an FRW universe and the corresponding modified metric, veirbein and spin connection components are obtained. Moreover, using the Hamilton-Jacobi method and as a pure space-time deformation effect, the NCG Hawking radiation via a fermionic tunneling transition through the dynamical NCG horizon is also studied.

  1. System and method employing a minimum distance and a load feature database to identify electric load types of different electric loads

    DOEpatents

    Lu, Bin; Yang, Yi; Sharma, Santosh K; Zambare, Prachi; Madane, Mayura A

    2014-12-23

    A method identifies electric load types of a plurality of different electric loads. The method includes providing a load feature database of a plurality of different electric load types, each of the different electric load types including a first load feature vector having at least four different load features; sensing a voltage signal and a current signal for each of the different electric loads; determining a second load feature vector comprising at least four different load features from the sensed voltage signal and the sensed current signal for a corresponding one of the different electric loads; and identifying by a processor one of the different electric load types by determining a minimum distance of the second load feature vector to the first load feature vector of the different electric load types of the load feature database.

  2. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sergyeyev, Artur; Krtous, Pavel; Institute of Theoretical Physics, Faculty of Mathematics and Physics, Charles University in Prague, V Holesovickach 2, Prague

    We consider the Klein-Gordon equation in generalized higher-dimensional Kerr-NUT-(A)dS spacetime without imposing any restrictions on the functional parameters characterizing the metric. We establish commutativity of the second-order operators constructed from the Killing tensors found in [J. High Energy Phys. 02 (2007) 004] and show that these operators, along with the first-order operators originating from the Killing vectors, form a complete set of commuting symmetry operators (i.e., integrals of motion) for the Klein-Gordon equation. Moreover, we demonstrate that the separated solutions of the Klein-Gordon equation obtained in [J. High Energy Phys. 02 (2007) 005] are joint eigenfunctions for all of thesemore » operators. We also present an explicit form of the zero mode for the Klein-Gordon equation with zero mass. In the semiclassical approximation we find that the separated solutions of the Hamilton-Jacobi equation for geodesic motion are also solutions for a set of Hamilton-Jacobi-type equations which correspond to the quadratic conserved quantities arising from the above Killing tensors.« less

  3. Primary and secondary battery consumption trends in Sweden 1996-2013: method development and detailed accounting by battery type.

    PubMed

    Patrício, João; Kalmykova, Yuliya; Berg, Per E O; Rosado, Leonardo; Åberg, Helena

    2015-05-01

    In this article, a new method based on Material Flow Accounting is proposed to study detailed material flows in battery consumption that can be replicated for other countries. The method uses regularly available statistics on import, industrial production and export of batteries and battery-containing electric and electronic equipment (EEE). To promote method use by other scholars with no access to such data, several empirically results and their trends over time, for different types of batteries occurrence among the EEE types are provided. The information provided by the method can be used to: identify drivers of battery consumption; study the dynamic behavior of battery flows - due to technology development, policies, consumers behavior and infrastructures. The method is exemplified by the study of battery flows in Sweden for years 1996-2013. The batteries were accounted, both in units and weight, as primary and secondary batteries; loose and integrated; by electrochemical composition and share of battery use between different types of EEE. Results show that, despite a fivefold increase in the consumption of rechargeable batteries, they account for only about 14% of total use of portable batteries. Recent increase in digital convergence has resulted in a sharp decline in the consumption of primary batteries, which has now stabilized at a fairly low level. Conversely, the consumption of integrated batteries has increased sharply. In 2013, 61% of the total weight of batteries sold in Sweden was collected, and for the particular case of alkaline manganese dioxide batteries, the value achieved 74%. Copyright © 2015 Elsevier Ltd. All rights reserved.

  4. Dynamic optimization and its relation to classical and quantum constrained systems

    NASA Astrophysics Data System (ADS)

    Contreras, Mauricio; Pellicer, Rely; Villena, Marcelo

    2017-08-01

    We study the structure of a simple dynamic optimization problem consisting of one state and one control variable, from a physicist's point of view. By using an analogy to a physical model, we study this system in the classical and quantum frameworks. Classically, the dynamic optimization problem is equivalent to a classical mechanics constrained system, so we must use the Dirac method to analyze it in a correct way. We find that there are two second-class constraints in the model: one fix the momenta associated with the control variables, and the other is a reminder of the optimal control law. The dynamic evolution of this constrained system is given by the Dirac's bracket of the canonical variables with the Hamiltonian. This dynamic results to be identical to the unconstrained one given by the Pontryagin equations, which are the correct classical equations of motion for our physical optimization problem. In the same Pontryagin scheme, by imposing a closed-loop λ-strategy, the optimality condition for the action gives a consistency relation, which is associated to the Hamilton-Jacobi-Bellman equation of the dynamic programming method. A similar result is achieved by quantizing the classical model. By setting the wave function Ψ(x , t) =e iS(x , t) in the quantum Schrödinger equation, a non-linear partial equation is obtained for the S function. For the right-hand side quantization, this is the Hamilton-Jacobi-Bellman equation, when S(x , t) is identified with the optimal value function. Thus, the Hamilton-Jacobi-Bellman equation in Bellman's maximum principle, can be interpreted as the quantum approach of the optimization problem.

  5. A method for studying the hunting oscillations of an airplane with a simple type of automatic control

    NASA Technical Reports Server (NTRS)

    Jones, Robert T

    1944-01-01

    A method is presented for predicting the amplitude and frequency, under certain simplifying conditions, of the hunting oscillations of an automatically controlled aircraft with lag in the control system or in the response of the aircraft to the controls. If the steering device is actuated by a simple right-left type of signal, the series of alternating fixed-amplified signals occurring during the hunting may ordinarily be represented by a "square wave." Formulas are given expressing the response to such a variations of signal in terms of the response to a unit signal. A more complex type of hunting, which may involve cyclic repetition of signals of varying duration, has not been treated and requires further analysis. Several examples of application of the method are included and the results discussed.

  6. Molecular typing of Vibrio parahaemolyticus strains isolated from the Philippines by PCR-based methods.

    PubMed

    Maluping, R P; Ravelo, C; Lavilla-Pitogo, C R; Krovacek, K; Romalde, J L

    2005-01-01

    The main aim of the present study was to use three PCR-based techniques for the analysis of genetic variability among Vibrio parahaemolyticus strains isolated from the Philippines. Seventeen strains of V. parahaemolyticus isolated from shrimps (Penaeus monodon) and from the environments where these shrimps are being cultivated were analysed by random amplified polymorphic DNA PCR (RAPD-PCR), enterobacterial repetitive intergenic consensus sequence PCR (ERIC-PCR) and repetitive extragenic palindromic PCR (REP-PCR). The results of this work have demonstrated genetic variability within the V. parahaemolyticus strains that were isolated from the Philippines. In addition, RAPD, ERIC and REP-PCR are suitable rapid typing methods for V. parahaemolyticus. All three methods have good discriminative ability and can be used as a rapid means of comparing V. parahaemolyticus strains for epidemiological investigation. Based on the results of this study, we could say that REP-PCR is inferior to RAPD and ERIC-PCR owing to the fact that it is less reproducible. Moreover, the REP-PCR analysis yielded a relatively small number of products. This may suggests that the REP sequences may not be widely distributed in the V. parahaemolyticus genome. Genetic variability within V. parahaemolyticus strains isolated in the Philippines has been demonstrated. The presence of ERIC and REP sequences in the genome of this bacterial species was confirmed. The RAPD, ERIC and REP-PCR techniques are useful methods for molecular typing of V. parahaemolyticus strains. To our knowledge this is the first study of this kind carried out on V. parahaemolyticus strains isolated from the Philippines.

  7. A spectrophotometric method for detecting substellar companions to late-type M stars

    NASA Astrophysics Data System (ADS)

    Oetiker, Brian Glen

    The most common stars in the Galaxy are the main-sequence M stars, yet current techniques are not optimized for detecting companions around the lowest mass stars; those with spectral designations ranging from M6 to M10. Described in this study is a search for companions around such stars using two methods: a unique implementation of the transit method, and a newly designed differential spectrophotometric method. The TEP project focusses on the detection of transits of terrestrial sized and larger companions in the eclipsing binary system CM Draconis. The newly designed spectrophotometric technique combines the strengths of the spectroscopic and photometric methods, while minimizing their inherent weaknesses. This unique method relies on the placement of three narrow band optical filters on and around the Titanium Oxide (TiO) bandhead near 8420 Å, a feature commonly seen in the atmospheres of late M stars. One filter is placed on the slope of the bandhead feature, while the remaining two are located on the adjacent continuum portions of the star's spectrum. The companion-induced motion of the star results in a doppler shifting of the bandhead feature, which in turn causes a change in flux passing through the filter located on the slope of the TiO bandhead. The spectrophotometric method is optimized for detecting compact systems containing brown dwarfs and giant planets. Because of its low dispersion-high photon efficiency design, this method is well suited for surveying large numbers of faint M stars. A small scale survey has been implemented, producing a candidate brown dwarf class companion of the star WX UMa. Applying the spectrophotometric method to a larger scale survey for brown dwarf and giant planet companions, coupled with a photometric transit study addresses two key astronomical issues. By detecting or placing limits on compact late type M star systems, a discrimination among competing theories of planetary formation may be gained. Furthermore, searching

  8. Query Optimization by Semantic Reasoning.

    DTIC Science & Technology

    1981-05-01

    condition holds, then formulas X and Y are said to be ,nerge-compatible. Let xi be the variable in X that corresponds to variable yj in Y (x is not...Davidson, Ramez EI-Masri, Sheldon Finkelstein, Hector Garcia, Mohammed Olumi, Tom Rogers, Neil Rowe, David Shaw, and Kyu-Young Whang . Special credit...for the simple queries, along with cost formulas and applicability conditions for the methods. Most recently has come the development of optimizers for

  9. Numerically Exact Calculation of Rovibrational Levels of Cl^-H_2O

    NASA Astrophysics Data System (ADS)

    Wang, Xiao-Gang; Carrington, Tucker

    2014-06-01

    Large amplitude vibrations of Van der Waals clusters are important because they reveal large regions of a potential energy surface (PES). To calculate spectra of Van der Waals clusters it is common to use an adiabatic approximation. When coupling between intra- and inter-molecular coordinates is important non-adiabatic coupling cannot be neglected and it is therefore critical to develop and test theoretical methods that couple both types of coordinates. We have developed new product basis and contracted basis Lanczos methods for Van der Waals complexes and tested them by computing rovibrational energy levels of Cl^-H_2O. The new product basis is made of functions of the inter-monomer distance, Wigner functions that depend on Euler angles specifying the orientation of H_2O with respect to a frame attached to the inter-monomer Jacobi vector, basis functions for H_2O vibration, and Wigner functions that depend on Euler angles specifying the orientation of the inter-monomer Jacobi vector with respect to a space-fixed frame. An advantage of this product basis is that it can be used to make an efficient contracted basis by replacing the vibrational basis functions for the monomer with monomer vibrational wavefunctions. Due to weak coupling between intra- and inter-molecular coordinates, only a few tens of monomer vibrational wavefunctions are necessary. The validity of the two new methods is established by comparing energy levels with benchmark rovibrational levels obtained with polyspherical coordinates and spherical harmonic type basis functions. For all bases, product structure is exploited to calculate eigenvalues with the Lanczos algorithm. For Cl^-H_2O, we are able, for the first time, to compute accurate splittings due to tunnelling between the two equivalent C_s minima. We use the PES of Rheinecker and Bowman (RB). Our results are in good agreement with experiment for the five fundamental bands observed. J. Rheinecker and J. M. Bowman, J. Chem. Phys. 124 131102

  10. Errors in accident data, its types, causes and methods of rectification-analysis of the literature.

    PubMed

    Ahmed, Ashar; Sadullah, Ahmad Farhan Mohd; Yahya, Ahmad Shukri

    2017-07-29

    Most of the decisions taken to improve road safety are based on accident data, which makes it the back bone of any country's road safety system. Errors in this data will lead to misidentification of black spots and hazardous road segments, projection of false estimates pertinent to accidents and fatality rates, and detection of wrong parameters responsible for accident occurrence, thereby making the entire road safety exercise ineffective. Its extent varies from country to country depending upon various factors. Knowing the type of error in the accident data and the factors causing it enables the application of the correct method for its rectification. Therefore there is a need for a systematic literature review that addresses the topic at a global level. This paper fulfils the above research gap by providing a synthesis of literature for the different types of errors found in the accident data of 46 countries across the six regions of the world. The errors are classified and discussed with respect to each type and analysed with respect to income level; assessment with regard to the magnitude for each type is provided; followed by the different causes that result in their occurrence, and the various methods used to address each type of error. Among high-income countries the extent of error in reporting slight, severe, non-fatal and fatal injury accidents varied between 39-82%, 16-52%, 12-84%, and 0-31% respectively. For middle-income countries the error for the same categories varied between 93-98%, 32.5-96%, 34-99% and 0.5-89.5% respectively. The only four studies available for low-income countries showed that the error in reporting non-fatal and fatal accidents varied between 69-80% and 0-61% respectively. The logistic relation of error in accident data reporting, dichotomised at 50%, indicated that as the income level of a country increases the probability of having less error in accident data also increases. Average error in recording information related to the

  11. Recommendations for choosing an analysis method that controls Type I error for unbalanced cluster sample designs with Gaussian outcomes.

    PubMed

    Johnson, Jacqueline L; Kreidler, Sarah M; Catellier, Diane J; Murray, David M; Muller, Keith E; Glueck, Deborah H

    2015-11-30

    We used theoretical and simulation-based approaches to study Type I error rates for one-stage and two-stage analytic methods for cluster-randomized designs. The one-stage approach uses the observed data as outcomes and accounts for within-cluster correlation using a general linear mixed model. The two-stage model uses the cluster specific means as the outcomes in a general linear univariate model. We demonstrate analytically that both one-stage and two-stage models achieve exact Type I error rates when cluster sizes are equal. With unbalanced data, an exact size α test does not exist, and Type I error inflation may occur. Via simulation, we compare the Type I error rates for four one-stage and six two-stage hypothesis testing approaches for unbalanced data. With unbalanced data, the two-stage model, weighted by the inverse of the estimated theoretical variance of the cluster means, and with variance constrained to be positive, provided the best Type I error control for studies having at least six clusters per arm. The one-stage model with Kenward-Roger degrees of freedom and unconstrained variance performed well for studies having at least 14 clusters per arm. The popular analytic method of using a one-stage model with denominator degrees of freedom appropriate for balanced data performed poorly for small sample sizes and low intracluster correlation. Because small sample sizes and low intracluster correlation are common features of cluster-randomized trials, the Kenward-Roger method is the preferred one-stage approach. Copyright © 2015 John Wiley & Sons, Ltd.

  12. AZTEC: A parallel iterative package for the solving linear systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hutchinson, S.A.; Shadid, J.N.; Tuminaro, R.S.

    1996-12-31

    We describe a parallel linear system package, AZTEC. The package incorporates a number of parallel iterative methods (e.g. GMRES, biCGSTAB, CGS, TFQMR) and preconditioners (e.g. Jacobi, Gauss-Seidel, polynomial, domain decomposition with LU or ILU within subdomains). Additionally, AZTEC allows for the reuse of previous preconditioning factorizations within Newton schemes for nonlinear methods. Currently, a number of different users are using this package to solve a variety of PDE applications.

  13. New Techniques in Computational Aerodynamics.

    DTIC Science & Technology

    1987-08-06

    the nature of a continuous range of nearby flow fields is of fundmental significance in the design and performance of aircraft. To treat this...parameters. The resulting matrix of derivatives of flow quantities is referred to as the Jacobi matrix. The subsequent procedure is in principle now...employed here also results in a method which is closely related to the method of characteristics. Special account must be taken of the appearance of

  14. Use of various diagnostic methods in a patient with Gaucher disease type I.

    PubMed

    Farahati, J; Trenn, G; John-Mikolajewski, V; Zander, C; Pastores, G M; Sciuk, J; Reiners, C

    1996-08-01

    A series of plain radiographs, bone scans, bone marrow scans, and MRIs is reported in a patient with Gaucher disease type I, in whom two episodes of acute bone crisis developed during a 6-year period of follow-up. Acute bone crisis and global indolent bone marrow displacement could both be assessed by bone marrow scintigraphy, whereas MRI could better clarify the corti-comedullary alteration after bone infarction. Thus, MRI and bone marrow scintigraphy could be used as complementary imaging methods in the management of patients with Gaucher disease.

  15. Coupled-rearrangement-channels calculation of the three-body system under the absorbing boundary condition

    NASA Astrophysics Data System (ADS)

    Iwasaki, M.; Otani, R.; Ito, M.; Kamimura, M.

    2016-05-01

    We formulate the method of the absorbing boundary condition (ABC) in the coupled-rearrangement-channels variational method (CRCMV) for the three-body problem. In the present study, we handle the simple three-boson system, and the absorbing potential is introduced in the Jacobi coordinate in the individual rearrangement channels. The resonance parameters and the strength of the monopole breakup are compared with the complex scaling method (CSM). We have found that the CRCVM + ABC method nicely works in the threebody problem with the rearrangement channels.

  16. 48 CFR 235.006 - Contracting methods and contract type.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Defense (Acquisition, Technology, and Logistics) (USD(AT&L)) of an intent not to exercise a fixed-price... award a fixed-price type contract for a development program effort unless— (1) The level of program risk permits realistic pricing; (2) The use of a fixed-price type contract permits an equitable and sensible...

  17. Nearly associative deformation quantization

    NASA Astrophysics Data System (ADS)

    Vassilevich, Dmitri; Oliveira, Fernando Martins Costa

    2018-04-01

    We study several classes of non-associative algebras as possible candidates for deformation quantization in the direction of a Poisson bracket that does not satisfy Jacobi identities. We show that in fact alternative deformation quantization algebras require the Jacobi identities on the Poisson bracket and, under very general assumptions, are associative. At the same time, flexible deformation quantization algebras exist for any Poisson bracket.

  18. Fundamental Study on Quantum Nanojets

    DTIC Science & Technology

    2004-08-01

    Pergamon Press. Bell , J. S . 1966 On the problem of hidden variables in quantum mechanics. Rev. of Modern Phys., 38, 447. Berndl, K., Daumer, M...fluid dynamics based on two quantum mechanical perspectives; Schrödinger’s wave mechanics and quantum fluid dynamics based on Hamilton-Jacoby...References 8 2). Direct Problems a). Quantum fluid dynamics formalism based on Hamilton-Jacoby equation are adapted for the numerical

  19. Synthesis and catalytic activity of Birnessite-Type Manganese Oxide synthesized by solvent-free method

    NASA Astrophysics Data System (ADS)

    Siregar, S. S.; Awaluddin, A.

    2018-04-01

    Redox reaction between KMnO4 and glucose usingsolvent-free method produces the octahedral layer birnessite-type manganese oxide. The effects of mole ratios, temperatures, and calcinations time on the structures and crystallinity of the oxides were studied throughthe X-ray powder diffraction analysis. The mole ratio of KMnO4/glucose (1:3) produces the purebirnessite with low crystallinity, whereas the mole ratio of KMnO4/glucose (3:1) yields high crystalline birnessite with minor components of hausmannite-type manganese oxide.The increasing of the temperature and calcinations times (300-700 °C and 3-7 h, respectively) willimprove the crystallinity and the purity of the as-synthesized oxide. Further experiments also showed that the as-syntesized octahedral layer birnessite-type manganese oxides have catalytic activity on the degradation of methylene blue (MB) dye with H2O2 as oxidant. The results revealed that the effective degradation could be achieved only in the presence of both the birnessite and H2O2, whereas without the addition of catalyst (H2O2only) or addition of H2O2 (catalyst only), the 3.5% and 15.5% of MB removal were obtained, respectively.

  20. State of the art of immunoassay methods for B-type natriuretic peptides: An update.

    PubMed

    Clerico, Aldo; Franzini, Maria; Masotti, Silvia; Prontera, Concetta; Passino, Claudio

    2015-01-01

    The aim of this review article is to give an update on the state of the art of the immunoassay methods for the measurement of B-type natriuretic peptide (BNP) and its related peptides. Using chromatographic procedures, several studies reported an increasing number of circulating peptides related to BNP in human plasma of patients with heart failure. These peptides may have reduced or even no biological activity. Furthermore, other studies have suggested that, using immunoassays that are considered specific for BNP, the precursor of the peptide hormone, proBNP, constitutes a major portion of the peptide measured in plasma of patients with heart failure. Because BNP immunoassay methods show large (up to 50%) systematic differences in values, the use of identical decision values for all immunoassay methods, as suggested by the most recent international guidelines, seems unreasonable. Since proBNP significantly cross-reacts with all commercial immunoassay methods considered specific for BNP, manufacturers should test and clearly declare the degree of cross-reactivity of glycosylated and non-glycosylated proBNP in their BNP immunoassay methods. Clinicians should take into account that there are large systematic differences between methods when they compare results from different laboratories that use different BNP immunoassays. On the other hand, clinical laboratories should take part in external quality assessment (EQA) programs to evaluate the bias of their method in comparison to other BNP methods. Finally, the authors believe that the development of more specific methods for the active peptide, BNP1-32, should reduce the systematic differences between methods and result in better harmonization of results.

  1. Towards an accurate representation of electrostatics in classical force fields: Efficient implementation of multipolar interactions in biomolecular simulations

    NASA Astrophysics Data System (ADS)

    Sagui, Celeste; Pedersen, Lee G.; Darden, Thomas A.

    2004-01-01

    The accurate simulation of biologically active macromolecules faces serious limitations that originate in the treatment of electrostatics in the empirical force fields. The current use of "partial charges" is a significant source of errors, since these vary widely with different conformations. By contrast, the molecular electrostatic potential (MEP) obtained through the use of a distributed multipole moment description, has been shown to converge to the quantum MEP outside the van der Waals surface, when higher order multipoles are used. However, in spite of the considerable improvement to the representation of the electronic cloud, higher order multipoles are not part of current classical biomolecular force fields due to the excessive computational cost. In this paper we present an efficient formalism for the treatment of higher order multipoles in Cartesian tensor formalism. The Ewald "direct sum" is evaluated through a McMurchie-Davidson formalism [L. McMurchie and E. Davidson, J. Comput. Phys. 26, 218 (1978)]. The "reciprocal sum" has been implemented in three different ways: using an Ewald scheme, a particle mesh Ewald (PME) method, and a multigrid-based approach. We find that even though the use of the McMurchie-Davidson formalism considerably reduces the cost of the calculation with respect to the standard matrix implementation of multipole interactions, the calculation in direct space remains expensive. When most of the calculation is moved to reciprocal space via the PME method, the cost of a calculation where all multipolar interactions (up to hexadecapole-hexadecapole) are included is only about 8.5 times more expensive than a regular AMBER 7 [D. A. Pearlman et al., Comput. Phys. Commun. 91, 1 (1995)] implementation with only charge-charge interactions. The multigrid implementation is slower but shows very promising results for parallelization. It provides a natural way to interface with continuous, Gaussian-based electrostatics in the future. It is

  2. Semiclassics for matrix Hamiltonians: The Gutzwiller trace formula with applications to graphene-type systems

    NASA Astrophysics Data System (ADS)

    Vogl, M.; Pankratov, O.; Shallcross, S.

    2017-07-01

    We present a tractable and physically transparent semiclassical theory of matrix-valued Hamiltonians, i.e., those that describe quantum systems with internal degrees of freedoms, based on a generalization of the Gutzwiller trace formula for a n ×n dimensional Hamiltonian H (p ̂,q ̂) . The classical dynamics is governed by n Hamilton-Jacobi (HJ) equations that act in a phase space endowed with a classical Berry curvature encoding anholonomy in the parallel transport of the eigenvectors of H (p ,q ) ; these vectors describe the internal structure of the semiclassical particles. At the O (ℏ1) level and for nondegenerate HJ systems, this curvature results in an additional semiclassical phase composed of (i) a Berry phase and (ii) a dynamical phase resulting from the classical particles "moving through the Berry curvature". We show that the dynamical part of this semiclassical phase will, generally, be zero only for the case in which the Berry phase is topological (i.e., depends only on the winding number). We illustrate the method by calculating the Landau spectrum for monolayer graphene, the four-band model of AB bilayer graphene, and for a more complicated matrix Hamiltonian describing the silicene band structure. Finally, we apply our method to an inhomogeneous system consisting of a strain engineered one-dimensional moiré in bilayer graphene, finding localized states near the Dirac point that arise from electron trapping in a semiclassical moiré potential. The semiclassical density of states of these localized states we show to be in perfect agreement with an exact quantum mechanical calculation of the density of states.

  3. A Minimally Invasive Method for Retrieving Single Adherent Cells of Different Types from Cultures

    PubMed Central

    Zeng, Jia; Mohammadreza, Aida; Gao, Weimin; Merza, Saeed; Smith, Dean; Kelbauskas, Laimonas; Meldrum, Deirdre R.

    2014-01-01

    The field of single-cell analysis has gained a significant momentum over the last decade. Separation and isolation of individual cells is an indispensable step in almost all currently available single-cell analysis technologies. However, stress levels introduced by such manipulations remain largely unstudied. We present a method for minimally invasive retrieval of selected individual adherent cells of different types from cell cultures. The method is based on a combination of mechanical (shear flow) force and biochemical (trypsin digestion) treatment. We quantified alterations in the transcription levels of stress response genes in individual cells exposed to varying levels of shear flow and trypsinization. We report optimal temperature, RNA preservation reagents, shear force and trypsinization conditions necessary to minimize changes in the stress-related gene expression levels. The method and experimental findings are broadly applicable and can be used by a broad research community working in the field of single cell analysis. PMID:24957932

  4. Least absolute shrinkage and selection operator type methods for the identification of serum biomarkers of overweight and obesity: simulation and application.

    PubMed

    Vasquez, Monica M; Hu, Chengcheng; Roe, Denise J; Chen, Zhao; Halonen, Marilyn; Guerra, Stefano

    2016-11-14

    The study of circulating biomarkers and their association with disease outcomes has become progressively complex due to advances in the measurement of these biomarkers through multiplex technologies. The Least Absolute Shrinkage and Selection Operator (LASSO) is a data analysis method that may be utilized for biomarker selection in these high dimensional data. However, it is unclear which LASSO-type method is preferable when considering data scenarios that may be present in serum biomarker research, such as high correlation between biomarkers, weak associations with the outcome, and sparse number of true signals. The goal of this study was to compare the LASSO to five LASSO-type methods given these scenarios. A simulation study was performed to compare the LASSO, Adaptive LASSO, Elastic Net, Iterated LASSO, Bootstrap-Enhanced LASSO, and Weighted Fusion for the binary logistic regression model. The simulation study was designed to reflect the data structure of the population-based Tucson Epidemiological Study of Airway Obstructive Disease (TESAOD), specifically the sample size (N = 1000 for total population, 500 for sub-analyses), correlation of biomarkers (0.20, 0.50, 0.80), prevalence of overweight (40%) and obese (12%) outcomes, and the association of outcomes with standardized serum biomarker concentrations (log-odds ratio = 0.05-1.75). Each LASSO-type method was then applied to the TESAOD data of 306 overweight, 66 obese, and 463 normal-weight subjects with a panel of 86 serum biomarkers. Based on the simulation study, no method had an overall superior performance. The Weighted Fusion correctly identified more true signals, but incorrectly included more noise variables. The LASSO and Elastic Net correctly identified many true signals and excluded more noise variables. In the application study, biomarkers of overweight and obesity selected by all methods were Adiponectin, Apolipoprotein H, Calcitonin, CD14, Complement 3, C-reactive protein, Ferritin

  5. Numerical method for the solution of large systems of differential equations of the boundary layer type

    NASA Technical Reports Server (NTRS)

    Green, M. J.; Nachtsheim, P. R.

    1972-01-01

    A numerical method for the solution of large systems of nonlinear differential equations of the boundary-layer type is described. The method is a modification of the technique for satisfying asymptotic boundary conditions. The present method employs inverse interpolation instead of the Newton method to adjust the initial conditions of the related initial-value problem. This eliminates the so-called perturbation equations. The elimination of the perturbation equations not only reduces the user's preliminary work in the application of the method, but also reduces the number of time-consuming initial-value problems to be numerically solved at each iteration. For further ease of application, the solution of the overdetermined system for the unknown initial conditions is obtained automatically by applying Golub's linear least-squares algorithm. The relative ease of application of the proposed numerical method increases directly as the order of the differential-equation system increases. Hence, the method is especially attractive for the solution of large-order systems. After the method is described, it is applied to a fifth-order problem from boundary-layer theory.

  6. A comparison of moment-based methods of estimation for the log Pearson type 3 distribution

    NASA Astrophysics Data System (ADS)

    Koutrouvelis, I. A.; Canavos, G. C.

    2000-06-01

    The log Pearson type 3 distribution is a very important model in statistical hydrology, especially for modeling annual flood series. In this paper we compare the various methods based on moments for estimating quantiles of this distribution. Besides the methods of direct and mixed moments which were found most successful in previous studies and the well-known indirect method of moments, we develop generalized direct moments and generalized mixed moments methods and a new method of adaptive mixed moments. The last method chooses the orders of two moments for the original observations by utilizing information contained in the sample itself. The results of Monte Carlo experiments demonstrated the superiority of this method in estimating flood events of high return periods when a large sample is available and in estimating flood events of low return periods regardless of the sample size. In addition, a comparison of simulation and asymptotic results shows that the adaptive method may be used for the construction of meaningful confidence intervals for design events based on the asymptotic theory even with small samples. The simulation results also point to the specific members of the class of generalized moments estimates which maintain small values for bias and/or mean square error.

  7. Amazonia Introduced to General Relativity: The May 29, 1919, Solar Eclipse from a North-Brazilian Point of View

    NASA Astrophysics Data System (ADS)

    Crispino, Luís C. B.; de Lima, Marcelo C.

    2016-12-01

    In 1919, A. C. D. Crommelin and C. R. Davidson, British astronomers from the Greenwich Observatory in England, passed by Amazonia on their Brazilian journey aiming to measure the bending of stars' light rays during the total solar eclipse of May 29, 1919, and thereby put the theory of general relativity to the test. In the context of Crommelin's and Davidson's visit, we discuss how Amazonia was introduced to Einstein's theory of gravitation, and also the observations and repercussions of the May 29, 1919, solar eclipse in Belém, capital city of the North-Brazilian Pará state.

  8. Methodical principles of recognition different source types in an acoustic-emission testing of metal objects

    NASA Astrophysics Data System (ADS)

    Bobrov, A. L.

    2017-08-01

    This paper presents issues of identification of various AE sources in order to increase the information value of AE method. This task is especially relevant for complex objects, when factors that affect an acoustic path on an object of testing significantly affect parameters of signals recorded by sensor. Correlation criteria, sensitive to type of AE source in metal objects is determined in the article.

  9. A correction method for the axial maladjustment of transmission-type optical system based on aberration theory

    NASA Astrophysics Data System (ADS)

    Xu, Chunmei; Huang, Fu-yu; Yin, Jian-ling; Chen, Yu-dan; Mao, Shao-juan

    2016-10-01

    The influence of aberration on misalignment of optical system is considered fully, the deficiencies of Gauss optical correction method is pointed, and a correction method for transmission-type misalignment optical system is proposed based on aberration theory. The variation regularity of single lens aberration caused by axial displacement is analyzed, and the aberration effect is defined. On this basis, through calculating the size of lens adjustment induced by the image position error and the magnifying rate error, the misalignment correction formula based on the constraints of the aberration is deduced mathematically. Taking the three lens collimation system for an example, the test is carried out to validate this method, and its superiority is proved.

  10. Two-dimensional imaging of two types of radicals by the CW-EPR method

    NASA Astrophysics Data System (ADS)

    Czechowski, Tomasz; Krzyminiewski, Ryszard; Jurga, Jan; Chlewicki, Wojciech

    2008-01-01

    The CW-EPR method of image reconstruction is based on sample rotation in a magnetic field with a constant gradient (50 G/cm). In order to obtain a projection (radical density distribution) along a given direction, the EPR spectra are recorded with and without the gradient. Deconvolution, then gives the distribution of the spin density. Projection at 36 different angles gives the information that is necessary for reconstruction of the radical distribution. The problem becomes more complex when there are at least two types of radicals in the sample, because the deconvolution procedure does not give satisfactory results. We propose a method to calculate the projections for each radical, based on iterative procedures. The images of density distribution for each radical obtained by our procedure have proved that the method of deconvolution, in combination with iterative fitting, provides correct results. The test was performed on a sample of polymer PPS Br 111 ( p-phenylene sulphide) with glass fibres and minerals. The results indicated a heterogeneous distribution of radicals in the sample volume. The images obtained were in agreement with the known shape of the sample.

  11. Attention - Control in the Frequentistic Processing of Multidimensional Event Streams.

    DTIC Science & Technology

    1980-07-01

    Human memory. Annual Review of Psychology, 1979, 30, 63-702. Craik , F. I. M., & Lockhart , R. S. Levels of processing : A framework for memory research...1979; Jacoby & Craik , 1979). Thus, the notions of memora- bility (or retrievability) and levels of processing are tied closely in the sense that the...differing levels and degrees of elaborateness (Jacoby & Craik , 1979). Decisions as to which attributes receive elaborated processing and how they are

  12. Geometrical analysis of the LiCN vibrational dynamics: a stability geometrical indicator.

    PubMed

    Vergel, A; Benito, R M; Losada, J C; Borondo, F

    2014-02-01

    The vibrational dynamics of the LiNC/LiCN molecular system is examined making use of the Riemannian geometry. Stability and chaoticity are analyzed, in this context, by means of the Jacobi-Levi-Civita equations, derived from the Jacobi metric, and its solutions. A dynamical indicator, called stability geometrical indicator, is introduced in order to ascertain the dynamical characteristics of stability and chaos in the molecule under study.

  13. Tunneling splitting in double-proton transfer: direct diagonalization results for porphycene.

    PubMed

    Smedarchina, Zorka; Siebrand, Willem; Fernández-Ramos, Antonio

    2014-11-07

    Zero-point and excited level splittings due to double-proton tunneling are calculated for porphycene and the results are compared with experiment. The calculation makes use of a multidimensional imaginary-mode Hamiltonian, diagonalized directly by an effective reduction of its dimensionality. Porphycene has a complex potential energy surface with nine stationary configurations that allow a variety of tunneling paths, many of which include classically accessible regions. A symmetry-based approach is used to show that the zero-point level, although located above the cis minimum, corresponds to concerted tunneling along a direct trans - trans path; a corresponding cis - cis path is predicted at higher energy. This supports the conclusion of a previous paper [Z. Smedarchina, W. Siebrand, and A. Fernández-Ramos, J. Chem. Phys. 127, 174513 (2007)] based on the instanton approach to a model Hamiltonian of correlated double-proton transfer. A multidimensional tunneling Hamiltonian is then generated, based on a double-minimum potential along the coordinate of concerted proton motion, which is newly evaluated at the RI-CC2/cc-pVTZ level of theory. To make it suitable for diagonalization, its dimensionality is reduced by treating fast weakly coupled modes in the adiabatic approximation. This results in a coordinate-dependent mass of tunneling, which is included in a unique Hermitian form into the kinetic energy operator. The reduced Hamiltonian contains three symmetric and one antisymmetric mode coupled to the tunneling mode and is diagonalized by a modified Jacobi-Davidson algorithm implemented in the Jadamilu software for sparse matrices. The results are in satisfactory agreement with the observed splitting of the zero-point level and several vibrational fundamentals after a partial reassignment, imposed by recently derived selection rules. They also agree well with instanton calculations based on the same Hamiltonian.

  14. Entanglement, replicas, and Thetas

    NASA Astrophysics Data System (ADS)

    Mukhi, Sunil; Murthy, Sameer; Wu, Jie-Qiang

    2018-01-01

    We compute the single-interval Rényi entropy (replica partition function) for free fermions in 1+1d at finite temperature and finite spatial size by two methods: (i) using the higher-genus partition function on the replica Riemann surface, and (ii) using twist operators on the torus. We compare the two answers for a restricted set of spin structures, leading to a non-trivial proposed equivalence between higher-genus Siegel Θ-functions and Jacobi θ-functions. We exhibit this proposal and provide substantial evidence for it. The resulting expressions can be elegantly written in terms of Jacobi forms. Thereafter we argue that the correct Rényi entropy for modular-invariant free-fermion theories, such as the Ising model and the Dirac CFT, is given by the higher-genus computation summed over all spin structures. The result satisfies the physical checks of modular covariance, the thermal entropy relation, and Bose-Fermi equivalence.

  15. Quantum demolition filtering and optimal control of unstable systems.

    PubMed

    Belavkin, V P

    2012-11-28

    A brief account of the quantum information dynamics and dynamical programming methods for optimal control of quantum unstable systems is given to both open loop and feedback control schemes corresponding respectively to deterministic and stochastic semi-Markov dynamics of stable or unstable systems. For the quantum feedback control scheme, we exploit the separation theorem of filtering and control aspects as in the usual case of quantum stable systems with non-demolition observation. This allows us to start with the Belavkin quantum filtering equation generalized to demolition observations and derive the generalized Hamilton-Jacobi-Bellman equation using standard arguments of classical control theory. This is equivalent to a Hamilton-Jacobi equation with an extra linear dissipative term if the control is restricted to Hamiltonian terms in the filtering equation. An unstable controlled qubit is considered as an example throughout the development of the formalism. Finally, we discuss optimum observation strategies to obtain a pure quantum qubit state from a mixed one.

  16. A (2+1)-dimensional Korteweg-de Vries type equation in water waves: Lie symmetry analysis; multiple exp-function method; conservation laws

    NASA Astrophysics Data System (ADS)

    Adem, Abdullahi Rashid

    2016-05-01

    We consider a (2+1)-dimensional Korteweg-de Vries type equation which models the shallow-water waves, surface and internal waves. In the analysis, we use the Lie symmetry method and the multiple exp-function method. Furthermore, conservation laws are computed using the multiplier method.

  17. Relaxation and Preconditioning for High Order Discontinuous Galerkin Methods with Applications to Aeroacoustics and High Speed Flows

    NASA Technical Reports Server (NTRS)

    Shu, Chi-Wang

    2004-01-01

    This project is about the investigation of the development of the discontinuous Galerkin finite element methods, for general geometry and triangulations, for solving convection dominated problems, with applications to aeroacoustics. Other related issues in high order WENO finite difference and finite volume methods have also been investigated. methods are two classes of high order, high resolution methods suitable for convection dominated simulations with possible discontinuous or sharp gradient solutions. In [18], we first review these two classes of methods, pointing out their similarities and differences in algorithm formulation, theoretical properties, implementation issues, applicability, and relative advantages. We then present some quantitative comparisons of the third order finite volume WENO methods and discontinuous Galerkin methods for a series of test problems to assess their relative merits in accuracy and CPU timing. In [3], we review the development of the Runge-Kutta discontinuous Galerkin (RKDG) methods for non-linear convection-dominated problems. These robust and accurate methods have made their way into the main stream of computational fluid dynamics and are quickly finding use in a wide variety of applications. They combine a special class of Runge-Kutta time discretizations, that allows the method to be non-linearly stable regardless of its accuracy, with a finite element space discretization by discontinuous approximations, that incorporates the ideas of numerical fluxes and slope limiters coined during the remarkable development of the high-resolution finite difference and finite volume schemes. The resulting RKDG methods are stable, high-order accurate, and highly parallelizable schemes that can easily handle complicated geometries and boundary conditions. We review the theoretical and algorithmic aspects of these methods and show several applications including nonlinear conservation laws, the compressible and incompressible Navier

  18. Disc immuno-immobilization method for simultaneous typing and isolation of Salmonella flagellar phases.

    PubMed

    Mohit, B

    1968-07-01

    Salmonella organisms of an unknown serotype are inoculated in the center of a motility agar plate, and paper discs impregnated with antiflagellar antisera are placed in the periphery of the plate. The plate is incubated at room temperature overnight. During this time, the bacteria spread in a widening circle toward the discs, while the antiserum from each disc, in turn, diffuses centrifugally. When the motile organisms encounter an antiserum reacting with their flagella, they are immobilized. A semicircular line of immobilization is noted around the reactive antiserum disc. Eleven different Salmonella isolates were typed in duplicate by a standard method and by the immuno-immobilization method. Results obtained by the two methods were essentially identical. Simultaneously, single phases were isolated from the zone between the immobilization line and its antiserum disc. Isolates from this region were of the phase not immobilized by the antiserum disc. The dried discs, prepared in tris(hydroxymethyl)aminomethane buffer and stored at 4 C, were stable for at least 5 months. The method can be used for the study of relatedness of surface antigens of motile, growing bacteria, thus circumventing the need for solubilization of these antigens. The results obtained can be interpreted in a similar fashion to the "identity"-"nonidentity" lines of the Ochterlony double-diffusion technique for soluble antigens.

  19. A Modest Proposal: Permit Interlocutory Appeals of Summary Judgment Denials

    DTIC Science & Technology

    1994-04-01

    DTIC.FDAC DTIC 70A DOCaum~ ROCESS INr GAT NB •LD U•E RTONK LOAN DOCUMENT Best Availab le Copy A MODEST PROPOSAL: PERMIT INTERLOCUTORY APPEALS OF SUMMARY...PERMIT INTERLOCUTORY APPEALS OF SUMMARY JUDGMENT DENIALS Michael J. Davidson Major, U.S. Army Judge Advocate General’s Corps ABSTRACT: In 1986, the... interpreting Rule 56 of the Federal Rules of Civil Procedure, discusses the shortcomings of potential avenues of appeal , and suggests two methods by which

  20. A variational approach to multi-phase motion of gas, liquid and solid based on the level set method

    NASA Astrophysics Data System (ADS)

    Yokoi, Kensuke

    2009-07-01

    We propose a simple and robust numerical algorithm to deal with multi-phase motion of gas, liquid and solid based on the level set method [S. Osher, J.A. Sethian, Front propagating with curvature-dependent speed: Algorithms based on Hamilton-Jacobi formulation, J. Comput. Phys. 79 (1988) 12; M. Sussman, P. Smereka, S. Osher, A level set approach for capturing solution to incompressible two-phase flow, J. Comput. Phys. 114 (1994) 146; J.A. Sethian, Level Set Methods and Fast Marching Methods, Cambridge University Press, 1999; S. Osher, R. Fedkiw, Level Set Methods and Dynamics Implicit Surface, Applied Mathematical Sciences, vol. 153, Springer, 2003]. In Eulerian framework, to simulate interaction between a moving solid object and an interfacial flow, we need to define at least two functions (level set functions) to distinguish three materials. In such simulations, in general two functions overlap and/or disagree due to numerical errors such as numerical diffusion. In this paper, we resolved the problem using the idea of the active contour model [M. Kass, A. Witkin, D. Terzopoulos, Snakes: active contour models, International Journal of Computer Vision 1 (1988) 321; V. Caselles, R. Kimmel, G. Sapiro, Geodesic active contours, International Journal of Computer Vision 22 (1997) 61; G. Sapiro, Geometric Partial Differential Equations and Image Analysis, Cambridge University Press, 2001; R. Kimmel, Numerical Geometry of Images: Theory, Algorithms, and Applications, Springer-Verlag, 2003] introduced in the field of image processing.