Sample records for jain ron palmer

  1. Environmental Pride: Jain Shrine

    ERIC Educational Resources Information Center

    School Arts: The Art Education Magazine for Teachers, 2004

    2004-01-01

    The Cincinnati Art Museum's Jain shrine is an elaborate structure that allows Jains to contemplate a life of peace, discipline, and freedom from earthly desires. This shrine, an elaborately carved canopy (typically used by royalty) with two freestanding support pillars, was made during an important growth period that saw the building of numerous…

  2. 78 FR 19012 - Pawan Kumar Jain, M.D.; Decision And Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-28

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration [Docket No. 13-13] Pawan Kumar Jain, M.D...), I order that DEA Certificate of Registration BJ5128067, issued to Pawan Kumar Jain, M.D., be, and it hereby is, revoked. I further order that any pending application of Pawan Kumar Jain, M.D., to renew or...

  3. RON kinase isoforms demonstrate variable cell motility in normal cells.

    PubMed

    Greenbaum, Alissa; Rajput, Ashwani; Wan, Guanghua

    2016-09-01

    Aberrant RON (Recepteur d'Origine Nantais) tyrosine kinase activation causes the epithelial cell to evade normal growth pathways, resulting in unregulated cell proliferation, increased cell motility and decreased apoptosis. Wildtype (wt) RON has been shown to play a role in metastasis of epithelial malignancies. It presents an important potential therapeutic target for colorectal, breast, gastric and pancreatic cancer. Little is known about functional differences amongst RON isoforms RON155, RON160 and RON165. The purpose of this study was to determine the effect of various RON kinase isoforms on cell motility. Cell lines with stable expression of wtRON were generated by inserting the coding region of RON in pTagRFP (tagged red fluorescence protein plasmid). The expression constructs of RON variants (RON155, RON160 and RON165) were generated by creating a mutagenesis-based wtRON-pTag RFP plasmid and stably transfected into HEK 293 cells. The wound closure scratch assay was used to investigate the effect on cell migratory capacity of wild type RON and its variants. RON transfected cells demonstrated increased cell motility compared to HEK293 control cells. RON165 cell motility was significantly increased compared to RON160 (mean percentage of wound covered 37.37% vs. 32.40%; p = 0.03). RON tyrosine kinase isoforms have variable cell motility. This may reflect a difference in the behavior of malignant epithelial cells and their capacity for metastasis.

  4. Sallekhana: the ethicality and legality of religious suicide by starvation in the Jain religious community.

    PubMed

    Braun, Whitny

    2008-12-01

    This article examines Sallekhana, the Jain religious ritual of fasting to death, from the American and Indian legal and ethical perspectives. Two cases are presented. The first involves a woman in her twenties who starved herself to escape a voice in her head. The second case involves a woman with terminal cancer who chose to starve to death rather than accept palliative care. Both are analyzed with attention paid to the Jain theological rationale behind the practice and the social circumstances that predicate this vow. I argue that within Jain communities the moral presumption should be that Sallekhana is a valid religious ritual and should therefore be legally protected if it is freely chosen by an informed person free from coercion.

  5. Immunological responses induced by a DNA vaccine expressing RON4 and by immunogenic recombinant protein RON4 failed to protect mice against chronic toxoplasmosis.

    PubMed

    Rashid, Imran; Hedhli, Dorsaf; Moiré, Nathalie; Pierre, Josette; Debierre-Grockiego, Françoise; Dimier-Poisson, Isabelle; Mévélec, Marie Noëlle

    2011-11-08

    The development of an effective vaccine against Toxoplasma gondii infection is an important issue due to the seriousness of the related public health problems, and the economic importance of this parasitic disease worldwide. Rhoptry neck proteins (RONs) are components of the moving junction macromolecular complex formed during invasion. The aim of this study was to evaluate the vaccine potential of RON4 using two vaccination strategies: DNA vaccination by the intramuscular route, and recombinant protein vaccination by the nasal route. We produced recombinant RON4 protein (RON4S2) using the Schneider insect cells expression system, and validated its antigenicity and immunogenicity. We also constructed optimized plasmids encoding full length RON4 (pRON4), or only the N-terminal (pNRON4), or the C-terminal part (pCRON4) of RON4. CBA/J mice immunized with pRON4, pNRON4 or pCRON4 plus a plasmid encoding the granulocyte-macrophage-colony-stimulating factor showed high IgG titers against rRON4S2. Mice immunized by the nasal route with rRON4S2 plus cholera toxin exhibited low levels of anti-RON4S2 IgG antibodies, and no intestinal IgA antibodies specific to RON4 were detected. Both DNA and protein vaccination generated a mixed Th1/Th2 response polarized towards the IgG1 antibody isotype. Both DNA and protein vaccination primed CD4+ T cells in vivo. In addition to the production of IFN-γ, and IL-2, Il-10 and IL-5 were also produced by the spleen cells of the immunized mice stimulated with RON4S2, suggesting that a mixed Th1/Th2 type immune response occurred in all the immunized groups. No cytokine was detectable in stimulated mesenteric lymph nodes from mice immunized by the nasal route. Immune responses were induced by both DNA and protein vaccination, but failed to protect the mice against a subsequent oral challenge with T. gondii cysts. In conclusion, strategies designed to enhance the immunogenicity and to redirect the cellular response towards a Th1 type response

  6. Curcumin blocks RON tyrosine kinase-mediated invasion of breast carcinoma cells.

    PubMed

    Narasimhan, Madhusudhanan; Ammanamanchi, Sudhakar

    2008-07-01

    We have recently shown that macrophage-stimulating protein (MSP) promotes the invasion of recepteur d'origine nantais (RON), a tyrosine kinase receptor-positive MDA-MB-231, MDA-MB-468 breast cancer cells, and also identified the regulatory elements required for RON gene expression. In this report, we have analyzed the efficacy of a chemopreventive agent, curcumin, in blocking RON tyrosine kinase-mediated invasion of breast cancer cells. Reverse transcription-PCR and Western analysis indicated the down-regulation of the RON message and protein, respectively, in MDA-MB-231 and MDA-MB-468 cells. Significantly, curcumin-mediated inhibition of RON expression resulted in the blockade of RON ligand, MSP-induced invasion of breast cancer cells. We have identified two putative nuclear factor-kappaB p65 subunit binding sites on the RON promoter. Using chromatin immunoprecipitation analysis and site-directed mutagenesis of the RON promoter, we have confirmed the binding of p65 to the RON promoter. Our data show that curcumin reduces RON expression by affecting p65 protein expression and transcriptional activity. Treatment of MDA-MB-231 cells with pyrrolidine dithiocarbamate, an inhibitor of p65, or small interfering RNA knockdown of p65, blocked RON gene expression and MSP-mediated invasion of MDA-MB-231 cells. This is the first report showing the regulation of human RON gene expression by nuclear factor-kappaB and suggests a potential therapeutic role for curcumin in blocking RON tyrosine kinase-mediated invasion of carcinoma cells.

  7. Prognostic significance of phosphorylated RON in esophageal squamous cell carcinoma.

    PubMed

    Hui, Marco K C; Lai, Kenneth K Y; Chan, Kwok Wah; Luk, John M; Lee, Nikki P; Chung, Yvonne; Cheung, Leo C; Srivastava, Gopesh; Tsao, Sai Wah; Tang, Johnny C; Law, Simon

    2012-09-01

    Esophageal squamous cell carcinoma (ESCC) is the most common type of esophageal cancer. RON is a transmembrane receptor overexpressed in various cancers; however, the clinical significance of its phosphorylated form (pRON) is not fully deciphered. This report is the first to investigate the expression and clinical significance of pRON in human ESCC. Quantitative polymerase chain reaction revealed an up-regulation of RON mRNA in 70% (7/10) of ESCC tissues when compared to the adjacent nontumor tissues. An overexpression of pRON protein was found in most of the ESCC cell lines studied (4/5) when compared to two non-neoplastic esophageal epithelial cells using immunoblot. In 64 ESCC tissues, pRON was localized at the cell membrane, cytoplasm and nucleus in 15 (23.4%), 63 (98.4%) and 61 (95.3%) cases using immunohistochemistry. Patients having high expression of cytoplasmic pRON significantly associated with shorter median survival when compared to those with low expression (25.41 months vs. 14.43 months), suggesting cytoplasmic pRON as a potential marker for poor prognosis in ESCC patients.

  8. RON is not a prognostic marker for resectable pancreatic cancer.

    PubMed

    Tactacan, Carole M; Chang, David K; Cowley, Mark J; Humphrey, Emily S; Wu, Jianmin; Gill, Anthony J; Chou, Angela; Nones, Katia; Grimmond, Sean M; Sutherland, Robert L; Biankin, Andrew V; Daly, Roger J

    2012-09-07

    The receptor tyrosine kinase RON exhibits increased expression during pancreatic cancer progression and promotes migration, invasion and gemcitabine resistance of pancreatic cancer cells in experimental models. However, the prognostic significance of RON expression in pancreatic cancer is unknown. RON expression was characterized in several large cohorts, including a prospective study, totaling 492 pancreatic cancer patients and relationships with patient outcome and clinico-pathologic variables were assessed. RON expression was associated with outcome in a training set, but this was not recapitulated in the validation set, nor was there any association with therapeutic responsiveness in the validation set or the prospective study. Although RON is implicated in pancreatic cancer progression in experimental models, and may constitute a therapeutic target, RON expression is not associated with prognosis or therapeutic responsiveness in resected pancreatic cancer.

  9. The Ron Receptor Tyrosine Kinase Negatively Regulates Mammary Gland Branching Morphogenesis

    PubMed Central

    Meyer, Sara E.; Zinser, Glendon M.; Stuart, William D.; Pathrose, Peterson; Waltz, Susan E.

    2009-01-01

    The Ron receptor tyrosine kinase is expressed in normal breast tissue and is overexpressed in approximately 50% of human breast cancers. Despite the recent studies on Ron in breast cancer, nothing is known about the importance of this protein during breast development. To investigate the functional significance of Ron in the normal mammary gland, we compared mammary gland development in wild-type mice to mice containing a targeted ablation of the tyrosine kinase (TK) signaling domain of Ron (TK−/−). Mammary glands from RonTK−/− mice exhibited accelerated pubertal development including significantly increased ductal extension and branching morphogenesis. While circulating levels of estrogen, progesterone, and overall rates of epithelial cell turnover were unchanged, significant increases in phosphorylated MAPK, which predominantly localized to the epithelium, were associated with increased branching morphogenesis. Additionally, purified RonTK−/− epithelial cells cultured ex vivo exhibited enhanced branching morphogenesis, which was reduced upon MAPK inhibition. Microarray analysis of pubertal RonTK−/− glands revealed 393 genes temporally impacted by Ron expression with significant changes observed in signaling networks regulating development, morphogenesis, differentiation, cell motility, and adhesion. In total, these studies represent the first evidence of a role for the Ron receptor tyrosine kinase as a critical negative regulator of mammary development. PMID:19576199

  10. Mapping surrogate gasoline compositions into RON/MON space

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Morgan, Neal; Kraft, Markus; Smallbone, Andrew

    2010-06-15

    In this paper, new experimentally determined octane numbers (RON and MON) of blends of a tri-component surrogate consisting of toluene, n-heptane, i-octane (called toluene reference fuel TRF) arranged in an augmented simplex design are used to derive a simple response surface model for the octane number of any arbitrary TRF mixture. The model is second-order in its complexity and is shown to be more accurate to the standard ''linear-by-volume'' (LbV) model which is often used when no other information is available. Such observations are due to the existence of both synergistic and antagonistic blending of the octane numbers between themore » three components. In particular, antagonistic blending of toluene and iso-octane leads to a maximum in sensitivity that lies on the toluene/iso-octane line. The model equations are inverted so as to map from RON/MON space back into composition space. Enabling one to use two simple formulae to determine, for a given fuel with known RON and MON, the volume fractions of toluene, n-heptane and iso-octane to be blended in order to emulate that fuel. HCCI engine simulations using gasoline with a RON of 98.5 and a MON of 88 were simulated using a TRF fuel, blended according to the derived equations to match the RON and MON. The simulations matched the experimentally obtained pressure profiles well, especially when compared to simulations using only PRF fuels which matched the RON or MON. This suggested that the mapping is accurate and that to emulate a refinery gasoline, it is necessary to match not only the RON but also the MON of the fuel. (author)« less

  11. Short-Form Ron Promotes Spontaneous Breast Cancer Metastasis through Interaction with Phosphoinositide 3-Kinase

    PubMed Central

    Liu, Xuemei; Zhao, Ling; DeRose, Yoko S.; Lin, Yi-Chun; Bieniasz, Magdalena; Eyob, Henok; Buys, Saundra S.; Neumayer, Leigh

    2011-01-01

    Receptor tyrosine kinases (RTKs) have been the subject of intense investigation due to their widespread deregulation in cancer and the prospect of developing targeted therapeutics against these proteins. The Ron RTK has been implicated in tumor aggressiveness and is a developing target for therapy, but its function in tumor progression and metastasis is not fully understood. We examined Ron activity in human breast cancers and found striking predominance of an activated Ron isoform known as short-form Ron (sfRon), whose function in breast tumors has not been explored. We found that sfRon plays a significant role in aggressiveness of breast cancer in vitro and in vivo. sfRon expression was sufficient to convert slow-growing, nonmetastatic tumors into rapidly growing tumors that spontaneously metastasized to liver and bones. Mechanistic studies revealed that sfRon promotes epithelial-mesenchymal transition, invasion, tumor growth, and metastasis through interaction with p85, the regulatory subunit of phosphoinositide 3-kinase (PI3K). Inhibition of PI3K activity, or introduction of a single mutation in the p85 docking site on sfRon, completely eliminated the ability of sfRon to promote tumor growth, invasion, and metastasis. These findings reveal sfRon as an important new player in breast cancer and validate Ron and PI3K as therapeutic targets in this disease. PMID:22207901

  12. Interview with Ron Wasserstein

    ERIC Educational Resources Information Center

    Rossmann, Allan; Wasserstein, Ron

    2014-01-01

    Ron Wasserstein is Executive Director of the American Statistical Association (ASA). He previously served as Vice-President for Academic Affairs and Professor of Statistics at Washburn University. This interview took place via email on January 21- February 24, 2014. Topics covered in this interview are as follows: 1) Beginnings, 2) Teaching…

  13. John Twysden and John Palmer: 17th-century Northamptonshire astronomers

    NASA Astrophysics Data System (ADS)

    Frost, M. A.

    2008-01-01

    John Twysden (1607-1688) and John Palmer (1612-1679) were two astronomers in the circle of Samuel Foster (circa 1600-1652), the subject of a recent paper in this journal. John Twysden qualified in law and medicine and led a peripatetic life around England and Europe. John Palmer was Rector of Ecton, Northamptonshire and later Archdeacon of Northampton. The two astronomers catalogued observations made from Northamptonshire from the 1640s to the 1670s. In their later years Twysden and Palmer published works on a variety of topics, often astronomical. Palmer engaged in correspondence with Henry Oldenburg, the first secretary of the Royal Society, on topics in astronomy and mathematics.

  14. Multiple-Herbicide Resistance Is Widespread in Roadside Palmer Amaranth Populations.

    PubMed

    Bagavathiannan, Muthukumar V; Norsworthy, Jason K

    2016-01-01

    Herbicide-resistant Palmer amaranth is a widespread issue in row-crop production in the Midsouthern US. Palmer amaranth is commonly found on roadside habitats in this region, but little is known on the degree of herbicide resistance in these populations. Herbicide resistance in roadside Palmer amaranth populations can represent the spread of an adaptive trait across a selective landscape. A large-scale survey was carried out in the Mississippi Delta region of eastern Arkansas to document the level of resistance in roadside Palmer amaranth populations to pyrithiobac and glyphosate, two important herbicides with broad history of use in the region. A total of 215 Palmer amaranth populations collected across 500 random survey sites were used in the evaluations. About 89 and 73% of the surveyed populations showed >90% survival to pyrithiobac and glyphosate, respectively. Further, only 3% of the populations were completely susceptible to glyphosate, while none of the populations was completely controlled by pyrithiobac. Among the 215 populations evaluated, 209 populations showed multiple resistance to both pyrithiobac and glyphosate at varying degrees. Dose-response assays confirmed the presence of high levels of herbicide resistance in the five selected populations (≥ 25-fold compared to a susceptible standard). Results demonstrate the prevalence of multiple-herbicide resistance in roadside Palmer amaranth populations in this region. Growers should be vigilant of Palmer amaranth infestation in roadsides adjacent to their fields and implement appropriate control measures to prevent likely spread of herbicide resistance into their fields.

  15. Human RON receptor tyrosine kinase induces complete epithelial-to-mesenchymal transition but causes cellular senescence

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cote, Marceline; Miller, A. Dusty; Liu, Shan-Lu

    2007-08-17

    The RON receptor tyrosine kinase is a member of the MET proto-oncogene family and is important for cell proliferation, differentiation, and cancer development. Here, we created a series of Madin-Darby canine kidney (MDCK) epithelial cell clones that express different levels of RON, and have investigated their biological properties. While low levels of RON correlated with little morphological change in MDCK cells, high levels of RON expression constitutively led to morphological scattering or complete and stabilized epithelial-to-mesenchymal transition (EMT). Unexpectedly, MDCK clones expressing higher levels of RON exhibited retarded proliferation and senescence, despite increased motility and invasiveness. RON was constitutively tyrosine-phosphorylatedmore » in MDCK cells expressing high levels of RON and undergoing EMT, and the MAPK signaling pathway was activated. This study reveals for the first time that RON alone is sufficient to induce complete and stabilized EMT in MDCK cells, and overexpression of RON does not cause cell transformation but rather induces cell cycle arrest and senescence, leading to impaired cell proliferation.« less

  16. A Reassessment of R. R. Palmer's "The Age of Democratic Revolution."

    ERIC Educational Resources Information Center

    Cox, Marvin

    1991-01-01

    Compares Robert Palmer's interpretation of the French Revolution with the Marxist and revisionist views. Stresses Palmer's theory that the French Revolution belongs to the same spiritual family as the American. Reports that Palmer saw the French Revolution as the climactic event in a series of similar upheavals that integrated liberal democracy…

  17. A missing link between RON expression and oncological outcomes in resected left-sided pancreatic cancer.

    PubMed

    Han, Dai Hoon; Kang, Chang Moo; Lee, Sung Whan; Hwang, Ho Kyoung; Lee, Woo Jung

    2017-10-01

    Alteration and activation of recepteur d'origine nantais (RON) expression is known to be associated with cancer progression and decreased survival in various types of human cancer, including pancreatic cancer. Therefore, in the present study, RON expression levels were determined in resected left-sided pancreatic cancer to evaluate the potential oncological role of RON in the clinical setting of distal pancreatic cancer. From January 2005 to December 2011, a total of 57 patients underwent radical distal pancreatectomy for left-sided pancreatic cancer. Ductal adenocarcinoma was confirmed in all patients. Among these patients, 17 patients who received preoperative neoadjuvant treatment and 7 patients without available paraffin-embedded tissue blocks were excluded from the present study. RON expression in a the pancreatic cancer cell lines ASPC-1, BxPC-3, MiaPaCa-3 and Panc-1, as well as in resected left-sided pancreatic cancer specimens was determined by Western blot analysis. RON and vascular endothelial growth factor (VEGF) overexpression in resected left-sided pancreatic cancer was also evaluated by immunohistochemistry using pre-diluted anti-RON and anti-VEGF antibodies. An association was identified between the oncological outcome and RON overexpression. Increased levels of RON expression were observed in two pancreatic cancer cell lines, AsPC-1 and BxPC-3. RON overexpression was detected in specimens from 15/33 patients (45.5%) using immunohistochemistry. No significant association was identified between RON overexpression and VEGF overexpression (25.5 vs. 87.9%; P=0.667). No significant differences in disease-free survival or disease-specific survival associated with RON overexpression were identified. Although the results of previous studies have suggested that RON is a potential target for the treatment of pancreatic cancer, in the present study no association between RON overexpression and any adverse oncological effect was identified.

  18. Daniel David Palmer: alchemy in the creation of chiropractic.

    PubMed

    Gaucher-Peslherbe, P L

    1995-12-01

    D.D. Palmer has been a much ignored man in the discipline he founded. The same applies to several early concepts he used to develop from a mere healer's background: D.D. Palmer invested them with an entirely different meaning. When considered, they help to understand the inner logic that allowed for chiropractic survival. There was an alchemy in the creation of chiropractic and the senior Palmer was the alchemist. He has not been recognized even within his own profession for the self-taught scholar and clinician that he was, knowledgeable about the various medical and scientific theories of his time.

  19. Efficacy of anti-RON antibody Zt/g4-drug maytansinoid conjugation (Anti-RON ADC) as a novel therapeutics for targeted colorectal cancer therapy.

    PubMed

    Feng, Liang; Yao, Hang-Ping; Wang, Wei; Zhou, Yong-Qing; Zhou, Jianwei; Zhang, Ruiwen; Wang, Ming-Hai

    2014-12-01

    The receptor tyrosine kinase RON is critical in epithelial tumorigenesis and a drug target for cancer therapy. Here, we report the development and therapeutic efficacy of a novel anti-RON antibody Zt/g4-maytansinoid (DM1) conjugates for targeted colorectal cancer (CRC) therapy. Zt/g4 (IgG1a/κ) was conjugated to DM1 via thioether linkage to form Zt/g4-DM1 with a drug-antibody ratio of 4:1. CRC cell lines expressing different levels of RON were tested in vitro to determine Zt/g4-DM1-induced RON endocytosis, cell-cycle arrest, and cytotoxicity. Efficacy of Zt/g4-DM1 in vivo was evaluated in mouse xenograft CRC tumor model. Zt/g4-DM1 rapidly induced RON endocytosis, arrested cell cycle at G2-M phase, reduced cell viability, and caused massive cell death within 72 hours. In mouse xenograft CRC models, Zt/g4-DM1 at a single dose of 20 mg/kg body weight effectively delayed CRC cell-mediated tumor growth up to 20 days. In a multiple dose-ranging study with a five injection regimen, Zt/g4-DM1 inhibited more than 90% tumor growth at doses of 7, 10, and 15 mg/kg body weight. The minimal dose achieving 50% of tumor inhibition was approximately 5.0 mg/kg. The prepared Zt/g4-DM1 is stable at 37°C for up to 30 days. At 60 mg/kg, Zt/g4-DM1 had a moderate toxicity in vivo with an average of 12% reduction in mouse body weight. Zt/g4-DM1 is highly effective in targeted inhibition of CRC cell-derived tumor growth in mouse xenograft models. This work provides the basis for development of humanized Zt/g4-DM1 for RON-targeted CRC therapy in the future. ©2014 American Association for Cancer Research.

  20. Estrogen receptor alpha deletion enhances the metastatic phenotype of Ron overexpressing mammary tumors in mice

    PubMed Central

    2012-01-01

    Background The receptor tyrosine kinase family includes many transmembrane proteins with diverse physiological and pathophysiological functions. The involvement of tyrosine kinase signaling in promoting a more aggressive tumor phenotype within the context of chemotherapeutic evasion is gaining recognition. The Ron receptor is a tyrosine kinase receptor that has been implicated in the progression of breast cancer and evasion of tamoxifen therapy. Results Here, we report that Ron expression is correlated with in situ, estrogen receptor alpha (ERα)-positive tumors, and is higher in breast tumors following neoadjuvant tamoxifen therapy. We also demonstrate that the majority of mammary tumors isolated from transgenic mice with mammary specific-Ron overexpression (MMTV-Ron mice), exhibit appreciable ER expression. Moreover, genetic-ablation of ERα, in the context of Ron overexpression, leads to delayed mammary tumor initiation and growth, but also results in an increased metastasis. Conclusions Ron receptor overexpression is associated with ERα-positive human and murine breast tumors. In addition, loss of ERα on a Ron overexpressing background in mice leads to the development of breast tumors which grow slower but which exhibit more metastasis and suggests that targeting of ERα, as in the case of tamoxifen therapy, may reduce the growth of Ron overexpressing breast cancers but may cause these tumors to be more metastatic. PMID:22226043

  1. Palmer Amaranth Identification and Documentation of Herbicide Resistance in Argentina

    USDA-ARS?s Scientific Manuscript database

    Palmer amaranth (Amaranthuspalmeri S. Wats.) has greatly disrupted agricultural practices in the US with its rapid growth and rapid evolution of herbicide resistance. This weed species is now suspected in Argentina. To document whether the suspected plant populations are indeed Palmer amaranth, mo...

  2. A tribute to Dr. Ron W. Waynant (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Gannot, Israel; Ilev, Ilko K.; Anders, Juanita J.; Kang, Jin U.

    2017-02-01

    Ron, our beloved mentor, friend and colleague has passed away on May 7th, 2016. This presentation will follow his life and remarkable achievements. It will describe his work and original developments in three major fields of his interest: his early inventive work on vacuum ultraviolet laser radiation; specialty fiber-optics for laser transmission, especially high-power short-pulse broadband laser delivery of free-electron laser; and up to his latest work on Photobiomodulation. The authors will share their personal experience working with Ron - a Nobel and creative person, however, very humble.

  3. Ron Brown Scholar Program. Evaluation Summary

    ERIC Educational Resources Information Center

    Broton, Katie; Mueller, Dan

    2009-01-01

    The Ron Brown Scholar Program aims to be a major force in producing this nation's next generation of leaders by providing academic scholarships, service opportunities, and leadership experiences to exemplary young African Americans. The program is highly selective, with several hundred applicants per scholarship awarded. Students are selected…

  4. Palmer amaranth seed mortality in response to burial depth and time

    USDA-ARS?s Scientific Manuscript database

    Glyphosate resistant Palmer amaranth infests millions of arable acres in the SE US. One proposed method of reducing population numbers is to bury surface seeds deeply, below their optimal emergence zone. The objective of this study was to determine how burial longevity and depth impact Palmer amaran...

  5. In Conversation With Materials Scientist Ron Zuckermann

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ron Zuckerman

    2009-11-18

    Nov. 11, 2009: Host Alice Egan of Berkeley Lab's Materials Sciences Division interviews scientists about their lives and work in language everyone can understand. Her guest Berkeley Lab's Ron Zuckerman, who discusses biological nanostructures and the world of peptoids.

  6. In Conversation With Materials Scientist Ron Zuckermann

    ScienceCinema

    Ron Zuckerman

    2017-12-09

    Nov. 11, 2009: Host Alice Egan of Berkeley Lab's Materials Sciences Division interviews scientists about their lives and work in language everyone can understand. Her guest Berkeley Lab's Ron Zuckerman, who discusses biological nanostructures and the world of peptoids.

  7. RON (MST1R) is a novel prognostic marker and therapeutic target for gastroesophageal adenocarcinoma

    PubMed Central

    Catenacci, Daniel VT; Cervantes, Gustavo; Yala, Soheil; Nelson, Erik A; El-Hashani, Essam; Kanteti, Rajani; El Dinali, Mohamed; Hasina, Rifat; Brägelmann, Johannes; Seiwert, Tanguy; Sanicola, Michele; Henderson, Les; Grushko, Tatyana A; Olopade, Olufunmilayo; Karrison, Theodore; Bang, Yung-Jue; Ho Kim, Woo; Tretiakova, Maria; Vokes, Everett; Frank, David A; Kindler, Hedy L; Huet, Heather

    2011-01-01

    RON (MST1R) is one of two members of the MET receptor tyrosine kinase family, along with parent receptor MET. RON has a putative role in several cancers, but its expression and function is poorly characterized in gastroesophageal adenocarcinoma. A recognized functional role of MET tyrosine kinase in gastroesophageal cancer has led to early phase clinical trials using MET inhibitors, with unimpressive results. Therefore, the role of RON in gastroesophageal cancer, as well as its role in cooperative signaling with MET and as a mechanism of resistance to MET inhibition, was studied in gastroesophageal tissues and cell lines. By IHC, RON was highly overexpressed in 74% of gastroesophageal samples (n = 94) and overexpression was prognostic of poor survival (p = 0.008); RON and MET co-expression occurred in 43% of samples and was prognostic of worst survival (p = 0.03). High MST1R gene copy number by quantitative polymerase chain reaction and confirmed by fluorescence in situ hybridization and/or array comparative genomic hybridization, was seen in 35.5% (16/45) of cases. High MST1R gene copy number correlated with poor survival (p = 0.01), and was associated with high MET and ERBB2 gene copy number. a novel somatic MST1R juxtamembrane mutation R1018G was found in 11% of samples. RON signaling was functional in cell lines, activating downstream effector STAT3, and resulted in increased viability over controls. RON and MET co-stimulation assays led to enhanced malignant phenotypes over stimulation of either receptor alone. Growth inhibition as evidenced by viability and apoptosis assays was optimal using novel blocking monoclonal antibodies to both ROn and MET, versus either alone. SU11274, a classic MET small molecule tyrosine kinase inhibitor, blocked signaling of both receptors and proved synergistic when combined with STAT3 inhibition (combination index <1). These preclinical studies define RON as an important novel prognostic marker and therapeutic target for

  8. The RON Receptor Tyrosine Kinase Promotes Metastasis by Triggering MBD4-Dependent DNA Methylation Reprogramming

    PubMed Central

    Cunha, Stéphanie; Lin, Yi-Chun; Goossen, Elizabeth A.; DeVette, Christa I.; Albertella, Mark R.; Thomson, Stuart; Mulvihill, Mark J.; Welm, Alana L.

    2017-01-01

    SUMMARY Metastasis is the major cause of death in cancer patients, yet the genetic and epigenetic programs that drive metastasis are poorly understood. Here, we report an epigenetic reprogramming pathway that is required for breast cancer metastasis. Concerted differential DNA methylation is initiated by the activation of the RON receptor tyrosine kinase by its ligand, macrophage stimulating protein (MSP). Through PI3K signaling, RON/MSP promotes expression of the G:T mismatch-specific thymine glycosylase MBD4. RON/MSP and MBD4-dependent aberrant DNA methylation results in the misregulation of a specific set of genes. Knockdown of MBD4 reverses methylation at these specific loci and blocks metastasis. We also show that the MBD4 glycosylase catalytic residue is required for RON/MSP-driven metastasis. Analysis of human breast cancers revealed that this epigenetic program is significantly associated with poor clinical outcome. Furthermore, inhibition of Ron kinase activity with a pharmacological agent blocks metastasis of patient-derived breast tumor grafts in vivo. PMID:24388747

  9. Novel function of transcription factor Nrf2 as an inhibitor of RON tyrosine kinase receptor-mediated cancer cell invasion.

    PubMed

    Thangasamy, Amalraj; Rogge, Jessica; Krishnegowda, Naveen K; Freeman, James W; Ammanamanchi, Sudhakar

    2011-09-16

    Recepteur d' origine nantais (RON), a tyrosine kinase receptor, is aberrantly expressed in human tumors and promotes cancer cell invasion. RON receptor activation is also associated with resistance to tamoxifen treatment in breast cancer cells. Nrf2 is a positive regulator of cytoprotective genes. Using chromatin immunoprecipitation (ChIP) and site-directed mutagenesis studies of the RON promoter, we identified Nrf2 as a negative regulator of RON gene expression. High Nrf2 and low RON expression was observed in normal mammary tissue whereas high RON and low or undetectable expression of Nrf2 was observed in breast tumors. The Nrf2 inducer sulforaphane (SFN) as well as ectopic Nrf2 expression or knock-down of the Nrf2 negative regulator keap1, which stabilizes Nrf2, inhibited RON expression and invasion of carcinoma cells. Consequently, our studies identified a novel functional role for Nrf2 as a "repressor" and RON kinase as a molecular target of SFN, which mediates the anti-tumor effects of SFN. These results are not limited to breast cancer cells since the Nrf2 inducer SFN stabilized Nrf2 and inhibited RON expression in carcinoma cells from various tumor types.

  10. How to assess the plasma delivery of RONS into tissue fluid and tissue

    NASA Astrophysics Data System (ADS)

    Oh, Jun-Seok; Szili, Endre J.; Gaur, Nishtha; Hong, Sung-Ha; Furuta, Hiroshi; Kurita, Hirofumi; Mizuno, Akira; Hatta, Akimitsu; Short, Robert D.

    2016-08-01

    The efficacy of helium (He) and argon (Ar) plasma jets are being investigated for different healthcare applications including wound and cancer therapy, sterilisation and surface disinfections. Current research points to a potential link between the generation of reactive oxygen and nitrogen species (RONS) and outcomes in a range of biological and medical applications. As new data accrue, further strengthening this link, it becomes important to understand the controlled delivery of RONS into solutions, tissue fluids and tissues. This paper investigates the use of He and Ar plasma jets to deliver three RONS (hydrogen peroxide—H2O2, nitrite—\\text{NO}2- and nitrate—\\text{NO}3- ) and molecular oxygen (O2) directly into deionised (DI) water, or indirectly into DI water through an agarose target. The DI water is used in place of tissue fluid and the agarose target serves as a surrogate of tissue. Direct plasma jet treatments deliver more RONS and O2 than the through-agarose treatments for equivalent treatments times. The former only deliver RONS whilst the plasma jets are ignited; the latter continues to deliver RONS into the DI water long after the plasmas are extinguished. The He plasma jet is more effective at delivering H2O2 and \\text{NO}2- directly into DI water, but the Ar plasma jet is more effective at nitrating the DI water in both direct and through-agarose treatments. DI water directly treated with the plasma jets is deoxygenated, with the He plasma jet purging more O2 than the Ar plasma jet. This effect is known as ‘sparging’. In contrast, for through-agarose treatments both jets oxygenated the DI water. These results indicate that in the context of direct and indirect plasma jet treatments of real tissue fluids and tissue, the choice of process gas (He or Ar) could have a profound effect on the concentrations of RONS and O2. Irrespective of operating gas, sparging of tissue fluid (in an open wound) for long prolonged periods during direct plasma

  11. The Complete Loss of Tyrosine Kinase Receptors MET and RON Is a Poor Prognostic Factor in Patients with Extrahepatic Cholangiocarcinoma.

    PubMed

    Hayashi, Yuki; Yamaguchi, Junpei; Kokuryo, Toshio; Ebata, Tomoki; Yokoyama, Yukihiro; Igami, Tsuyoshi; Sugawara, Gen; Nagino, Masato

    2016-12-01

    Although the survival of patients with cholangiocarcinoma has improved, the prognosis remains unfavorable. The overexpression of mesenchymal-epithelial transition factor (MET) and recepteur d'origine nantais (RON) has been considered to be indicative of a poor prognosis in some types of cancer. On the other hand, some studies have shown that the expression of MET and RON is a favorable prognostic factor in certain types of tumors. Based on the immunohistochemical analysis of MET and RON, 290 patients who underwent resection for extrahepatic cholangiocarcinoma were divided into three groups: MET/RON-negative, -intermediate, and -positive. The associations between MET/RON expression and clinicopathological features, including prognosis, were analyzed. MET/RON-negativity was associated with nodal metastasis and advanced pathological stage. The overall 5-year survival rates were significantly lower in the MET/RON-negative and MET/RON-positive groups than in the MET/RON-intermediate group (28.3%, 32.4% and 48.5%, respectively; p=0.01). The complete loss of one or both MET and RON, as well as their overexpression, is a poor prognostic factor in patients with extrahepatic cholangiocarcinoma, probably due to the high rate of lymph-node metastasis. Copyright© 2016 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved.

  12. RON kinase inhibition reduces renal endothelial injury in sickle cell disease mice

    PubMed Central

    Khaibullina, Alfia; Adjei, Elena A.; Afangbedji, Nowah; Ivanov, Andrey; Kumari, Namita; Almeida, Luis E.F.; Quezado, Zenaide M.N.; Nekhai, Sergei; Jerebtsova, Marina

    2018-01-01

    Sickle cell disease patients are at increased risk of developing a chronic kidney disease. Endothelial dysfunction and inflammation associated with hemolysis lead to vasculopathy and contribute to the development of renal disease. Here we used a Townes sickle cell disease mouse model to examine renal endothelial injury. Renal disease in Townes mice was associated with glomerular hypertrophy, capillary dilation and congestion, and significant endothelial injury. We also detected substantial renal macrophage infiltration, and accumulation of macrophage stimulating protein 1 in glomerular capillary. Treatment of human cultured macrophages with hemin or red blood cell lysates significantly increased expression of macrophage membrane-associated protease that might cleave and activate circulating macrophage stimulating protein 1 precursor. Macrophage stimulating protein 1 binds to and activates RON kinase, a cell surface receptor tyrosine kinase. In cultured human renal glomerular endothelial cells, macrophage stimulating protein 1 induced RON downstream signaling, resulting in increased phosphorylation of ERK and AKT kinases, expression of Von Willebrand factor, increased cell motility, and re-organization of F-actin. Specificity of macrophage stimulating protein 1 function was confirmed by treatment with RON kinase inhibitor BMS-777607 that significantly reduced downstream signaling. Moreover, treatment of sickle cell mice with BMS-777607 significantly reduced glomerular hypertrophy, capillary dilation and congestion, and endothelial injury. Taken together, our findings demonstrated that RON kinase is involved in the induction of renal endothelial injury in sickle cell mice. Inhibition of RON kinase activation may provide a novel approach for prevention of the development of renal disease in sickle cell disease. PMID:29519868

  13. Glysphosate-resistant Palmer amaranth (Amaranthus palmeri) morphology,growth, and seed production in Georgia

    USDA-ARS?s Scientific Manuscript database

    Herbicide resistant Palmer amaranth has become the most economically detrimental weed of cotton in the Southeast US. With the continual marginalization of potential herbicide tools, research has expanded to include alternative means of affecting future Palmer amaranth populations by altering safe s...

  14. Glyphosate-resistant Palmer amaranth (Amaranthus palmeri) morphology, growth, and seed production in Georgia

    USDA-ARS?s Scientific Manuscript database

    Herbicide resistant Palmer amaranth has become the most economically detrimental weed of cotton in the Southeast US. With the continual marginalization of potential herbicide tools, research has expanded to include alternative means of affecting future Palmer amaranth populations by altering safe s...

  15. Hagai Ron (1944-2012)

    NASA Astrophysics Data System (ADS)

    Tauxe, Lisa

    2012-11-01

    Hagai Ron was born on a small kibbutz in Palestine, north of the Dead Sea. He passed away in the presence of his family on 10 September 2012. He is survived by three daughters and four grandchildren. After completing his Ph.D. at the Hebrew University of Jerusalem in 1984, he was a postdoctoral scholar at Stanford University, specializing in paleomagnetism and structural geology. He returned to Israel in 1987, building the first paleomagnetic laboratory in Israel at the Geophysical Institute of Israel. In 2001, he moved with his lab to the Hebrew University of Jerusalem, where he stayed until his retirement earlier this year.

  16. Characterizing the Hot Spots Involved in RON-MSPβ Complex Formation Using In Silico Alanine Scanning Mutagenesis and Molecular Dynamics Simulation

    PubMed Central

    Zarei, Omid; Hamzeh-Mivehroud, Maryam; Benvenuti, Silvia; Ustun-Alkan, Fulya; Dastmalchi, Siavoush

    2017-01-01

    Purpose: Implication of protein-protein interactions (PPIs) in development of many diseases such as cancer makes them attractive for therapeutic intervention and rational drug design. RON (Recepteur d’Origine Nantais) tyrosine kinase receptor has gained considerable attention as promising target in cancer therapy. The activation of RON via its ligand, macrophage stimulation protein (MSP) is the most common mechanism of activation for this receptor. The aim of the current study was to perform in silico alanine scanning mutagenesis and to calculate binding energy for prediction of hot spots in protein-protein interface between RON and MSPβ chain (MSPβ). Methods: In this work the residues at the interface of RON-MSPβ complex were mutated to alanine and then molecular dynamics simulation was used to calculate binding free energy. Results: The results revealed that Gln193, Arg220, Glu287, Pro288, Glu289, and His424 residues from RON and Arg521, His528, Ser565, Glu658, and Arg683 from MSPβ may play important roles in protein-protein interaction between RON and MSP. Conclusion: Identification of these RON hot spots is important in designing anti-RON drugs when the aim is to disrupt RON-MSP interaction. In the same way, the acquired information regarding the critical amino acids of MSPβ can be used in the process of rational drug design for developing MSP antagonizing agents, the development of novel MSP mimicking peptides where inhibition of RON activation is required, and the design of experimental site directed mutagenesis studies. PMID:28507948

  17. Palmer Quest: A Feasible Nuclear Fission "Vision Mission" to the Mars Polar Caps

    NASA Technical Reports Server (NTRS)

    Carsey, F. D.; Beegle, L. W.; Nakagawa, R.; Elliott, J. O.; Matthews, J. B.; Coleman, M. L.; Hecht, M. H.; Ivaniov, A. B.; Head, J. W.; Milkovich, S.

    2005-01-01

    We are engaged in a NASA Vision Mission study, called Palmer Quest after the American Antarctic explorer Nathaniel Palmer, to assess the presence of life and evaluate the habitability of the basal domain of the Mars polar caps. We address this goal through four objectives: 1. Determine the presence of amino acids, nutrients, and geochemical heterogeneity in the ice sheet. 2. Quantify and characterize the provenance of the amino acids in Mars ice. 3. Assess the stratification of outcropped units for indications of habitable zones. 4. Determine the accumulation of ice, mineralogic material, and amino acids in Mars ice caps over the present epoch. Because of the defined scientific goal for the vision mission, the Palmer Quest focus is astrobiological; however, the results of the study make us optimistic that aggressive multi-platform in-situ missions that address a wide range of objectives, such as climate change, can be supported by variations of the approach used on this mission. Mission Overview: The Palmer Quest baseline

  18. Isolation of Fully Human Antagonistic RON Antibodies Showing Efficient Block of Downstream Signaling and Cell Migration1

    PubMed Central

    Gunes, Zeynep; Zucconi, Adriana; Cioce, Mario; Meola, Annalisa; Pezzanera, Monica; Acali, Stefano; Zampaglione, Immacolata; De Pratti, Valeria; Bova, Luca; Talamo, Fabio; Demartis, Anna; Monaci, Paolo; La Monica, Nicola; Ciliberto, Gennaro; Vitelli, Alessandra

    2011-01-01

    RON belongs to the c-MET family of receptor tyrosine kinases. As its well-known family member MET, RON and its ligand macrophage-stimulating protein have been implicated in the progression and metastasis of tumors and have been shown to be overexpressed in cancer. We generated and tested a large number of human monoclonal antibodies (mAbs) against human RON. Our screening yielded three high-affinity antibodies that efficiently block ligand-dependent intracellular AKT and MAPK signaling. This effect correlates with the strong reduction of ligand-activated migration of T47D breast cancer cell line. By cross-competition experiments, we showed that the antagonistic antibodies fall into three distinct epitope regions of the RON extracellular Sema domain. Notably, no inhibition of tumor growth was observed in different epithelial tumor xenografts in nude mice with any of the antibodies. These results suggest that distinct properties beside ligand antagonism are required for anti-RON mAbs to exert antitumor effects in vivo. PMID:21286376

  19. Deletion of the Ron receptor tyrosine kinase domain in mice provides protection from endotoxin-induced acute liver failure.

    PubMed

    Leonis, Mike A; Toney-Earley, Kenya; Degen, Sandra J F; Waltz, Susan E

    2002-11-01

    The targeted deletion of the cytoplasmic domain of the Ron receptor tyrosine kinase (TK) in mice leads to exaggerated responses to injury in several murine models of inflammation as well as increased lethality in response to endotoxin (lipopolysaccharide [LPS]). Using a well-characterized model of LPS-induced acute liver failure (ALF) in galactosamine (GalN)-sensitized mice, we show that Ron TK(-/-) mice display marked protection compared with control Ron TK(+/+) mice. Whereas control mice have profound elevation of serum aminotransferase levels (a marker of hepatocyte injury) and hemorrhagic necrosis of the liver, in dramatic contrast, Ron TK(-/-) mice have mild elevation of aminotransferase levels and relatively normal liver histology. These findings are associated with a reduction in the number of liver cells undergoing apoptosis in Ron TK(-/-) mice. Paradoxically, treatment of Ron TK(-/-) mice with LPS/GalN leads to markedly elevated (3.5-fold) serum levels of tumor necrosis factor (TNF) alpha, a key inflammatory mediator in this liver injury model, as well as reduced amounts of interleukin (IL) 10 (a suppressor of TNF-alpha production) and interferon (IFN)-gamma (a TNF-alpha sensitizer). These results show that ablation of the TK activity of the Ron receptor leads to protection from the development of hepatocellular apoptosis in response to treatment with LPS/GalN, even in the presence of excessive levels of serum TNF-alpha. In conclusion, our studies show that the Ron receptor TK plays a critical role in modulating the response of the liver to endotoxin.

  20. The Ron Receptor Regulates Kupffer Cell-Dependent Cytokine Production and Hepatocyte Survival Following Endotoxin Exposure in Mice

    PubMed Central

    Stuart, William D.; Kulkarni, Rishikesh M.; Gray, Jerilyn K.; Vasiliauskas, Juozas; Leonis, Mike A.; Waltz, Susan E.

    2011-01-01

    Previous studies demonstrated that targeted deletion of the Ron receptor tyrosine kinase (TK) domain in mice leads to marked hepatocyte protection in a well-characterized model of lipopolysaccharide (LPS)-induced acute liver failure in D-galactosamine (GalN)-sensitized mice. Hepatocyte protection in TK−/− mice was observed despite paradoxically elevated serum levels of tumor necrosis factor alpha (TNFα). To understand the role of Ron in the liver, purified populations of Kupffer cells and hepatocytes from wild-type (TK+/+) and TK−/− mice were studied. Utilizing quantitative RT-PCR, we demonstrated that Ron is expressed in these cell-types. Moreover, we also recapitulated the protected hepatocyte phenotype and exaggerated cytokine production observed in the TK−/− mice in vivo through the use of purified cultured cells ex vivo. We show that isolated TK−/− Kupffer cells produce increased levels of TNFα and select cytokines compared to TK+/+ cells following LPS stimulation. We also show that conditioned media from LPS-treated TK−/− Kupffer cells was more toxic to hepatocytes than control media, suggesting the exaggerated levels of cytokines produced from the TK−/− Kupffer cells are detrimental to wild type hepatocytes. In addition, we observed that TK−/− hepatocytes were more resistant to cell death compared to TK+/+ hepatocytes, suggesting that Ron functions in both the epithelial and inflammatory cell compartments to regulate acute liver injury. These findings were confirmed in vivo in mice with hepatocyte and macrophage cell-type-specific conditional Ron deletions. Mice with Ron loss selectively in hepatocytes exhibited less liver damage and increased survival compared to mice with Ron loss in macrophages. In conclusion, we have dissected cell-type-specific roles for Ron such that this receptor modulates cytokine production from Kupffer cells and inhibits hepatocyte survival in response to injury. PMID:21520175

  1. Response to Anthony J. Palmer, "A Philosophical View of the General Education Core"

    ERIC Educational Resources Information Center

    Schuler, Nico

    2004-01-01

    Anthony J. Palmer's paper continues an absolutely necessary discussion on the general education core curriculum for American undergraduate students. Initially, Palmer summarized the global conditions with which we are presently confronted. This discussion led him to the reexamination of the general education core at the undergraduate level. The…

  2. Ron in Breast Development and Cancer

    DTIC Science & Technology

    2006-10-01

    forms of chemotherapy and radiation . Testing the efficacy of IMC-41A10 in other subcutaneous as well as orthotopic tumor xenograft models will also be...contained a number of mitotic figures, an increased nuclear to cytoplasmic ratio and a high degree of pleomorphism that resembles what is observed in...The tumors that developed as a result of Ron overexpression had a high degree of pleomorphism and an increase in the nuclear to cytoplasmic ratio

  3. Phenology of five Palmer amaranth (Amaranthus palmeri) populations grown in northern Indiana and Arkansas

    USDA-ARS?s Scientific Manuscript database

    Palmer amaranth is one of the most problematic weeds encountered in US cotton and soybean production, with infestations spreading northward. Recently, Palmer amaranth seed has been introduced to cropping areas across Indiana through contaminated feedstuffs and equipment. This research focused on the...

  4. Ron Scott d/b/a White Dog Painting Information Sheet

    EPA Pesticide Factsheets

    Ron Scott d/b/a White Dog Painting (the Company) is located in Kansas City, Missouri. The settlement involves renovation activities conducted at property constructed prior to 1978, located in Kansas City, Missouri.

  5. The RON receptor tyrosine kinase in pancreatic cancer pathogenesis and its potential implications for future targeted therapies.

    PubMed

    Kang, Chang Moo; Babicky, Michele L; Lowy, Andrew M

    2014-03-01

    Pancreatic cancer remains a devastating disease with a mortality rate that has not changed substantially in decades. Novel therapies are therefore desperately needed. The RON receptor tyrosine kinase has been identified as an important mediator of KRAS oncogene addiction and is overexpressed in the majority of pancreatic cancers. Preclinical studies show that inhibition of RON function decreases pancreatic cancer cell migration, invasion, and survival and can sensitize pancreatic cancer cells to chemotherapy. This article reviews the current state of knowledge regarding RON biology and pancreatic cancer and discusses its potential as a therapeutic target.

  6. Factors affecting potential for Palmer amaranth (Amaranthus palmeri) suppression by winter rye in Georgia, USA

    USDA-ARS?s Scientific Manuscript database

    Herbicide resistant Palmer amaranth (Amaranthus palmeri) has rapidly become a dominant weed management issue in agronomic crops of the Southeast US. The small size of Palmer amaranth seeds, relative to other common weeds, provides an opportunity to use physical weed control through high-residue, ro...

  7. Strategies of targeting the extracellular domain of RON tyrosine kinase receptor for cancer therapy and drug delivery.

    PubMed

    Zarei, Omid; Benvenuti, Silvia; Ustun-Alkan, Fulya; Hamzeh-Mivehroud, Maryam; Dastmalchi, Siavoush

    2016-12-01

    Cancer is one of the most important life-threatening diseases in the world. The current efforts to combat cancer are being focused on molecular-targeted therapies. The main purpose of such approaches is based on targeting cancer cell-specific molecules to minimize toxicity for the normal cells. RON (Recepteur d'Origine Nantais) tyrosine kinase receptor is one of the promising targets in cancer-targeted therapy and drug delivery. In this review, we will summarize the available agents against extracellular domain of RON with potential antitumor activities. The presented antibodies and antibody drug conjugates against RON in this review showed wide spectrum of in vitro and in vivo antitumor activities promising the hope for them entering the clinical trials. Due to critical role of extracellular domain of RON in receptor activation, the development of therapeutic agents against this region could lead to fruitful outcome in cancer therapy.

  8. Factors affecting potential for Palmer amaranth (Amaranthus palmeri) suppression by winter rye in Georgia, USA

    USDA-ARS?s Scientific Manuscript database

    Herbicide resistant Palmer amaranth has rapidly become a dominant weed management issue in agronomic crops of the Southeast U. S. The small size of Palmer amaranth seeds, relative to other common weeds, provides an opportunity to use physical weed control through high-biomass, rolled cover crop mul...

  9. The RON Receptor Tyrosine Kinase in Pancreatic Cancer Pathogenesis and Its Potential Implications for Future Targeted Therapies

    PubMed Central

    Kang, Chang Moo; Babicky, Michele L.; Lowy, Andrew M.

    2014-01-01

    Pancreatic cancer remains a devastating disease with a mortality rate that has not changed substantially in decades. Novel therapies are therefore desperately needed. The RON receptor tyrosine kinase has been identified as an important mediator of KRAS oncogene addiction and is over-expressed in the majority of pancreatic cancers. Preclinical studies that inhibition of RON function decrease pancreatic cancer cell migration, invasion and survival and can sensitize pancreatic cancer cells to chemotherapy. This article reviews the current state of knowledge regarding RON biology and pancreatic cancer and discusses its potential as a therapeutic target. PMID:24518495

  10. Universal DC Hall conductivity of Jain's state ν = N/2N +/- 1

    NASA Astrophysics Data System (ADS)

    Nguyen, Dung; Son, Dam

    We present the Fermi-liquid theory of the fractional quantum Hall effect to describe Jain's states with filling fraction ν =N/2 N +/- 1 , that are near half filling. We derive the DC Hall conductivity σH (t) in closed form within the validity of our model. The results show that, without long range interaction, DC Hall conductivity has the universal form which doesn't depend on the detail of short range Landau's parameters Fn. When long range interaction is included, DC Hall conductivity depends on both long range interaction and Landau's parameters. We also analyze the relation between DC Hall conductivity and static structure factor. This work was supported by the Chicago MRSEC, which is funded by NSF through Grant DMR-1420709.

  11. Ron Logan: An Insider's View of the Music Industry.

    ERIC Educational Resources Information Center

    Van Zandt, Kathryn

    2002-01-01

    Presents an interview with Ron Logan who has served as an executive vice president for Walt Disney Entertainment. Focuses on topics, such as: influential teachers in his life, his career, how he selects scripts for musical productions, and advice for students who want to work in the music industry. (CMK)

  12. Dissecting the interface between apicomplexan parasite and host cell: Insights from a divergent AMA–RON2 pair

    PubMed Central

    Parker, Michelle L.; Penarete-Vargas, Diana M.; Hamilton, Phineas T.; Guérin, Amandine; Dubey, Jitender P.; Perlman, Steve J.; Spano, Furio; Lebrun, Maryse; Boulanger, Martin J.

    2016-01-01

    Plasmodium falciparum and Toxoplasma gondii are widely studied parasites in phylum Apicomplexa and the etiological agents of severe human malaria and toxoplasmosis, respectively. These intracellular pathogens have evolved a sophisticated invasion strategy that relies on delivery of proteins into the host cell, where parasite-derived rhoptry neck protein 2 (RON2) family members localize to the host outer membrane and serve as ligands for apical membrane antigen (AMA) family surface proteins displayed on the parasite. Recently, we showed that T. gondii harbors a novel AMA designated as TgAMA4 that shows extreme sequence divergence from all characterized AMA family members. Here we show that sporozoite-expressed TgAMA4 clusters in a distinct phylogenetic clade with Plasmodium merozoite apical erythrocyte-binding ligand (MAEBL) proteins and forms a high-affinity, functional complex with its coevolved partner, TgRON2L1. High-resolution crystal structures of TgAMA4 in the apo and TgRON2L1-bound forms complemented with alanine scanning mutagenesis data reveal an unexpected architecture and assembly mechanism relative to previously characterized AMA–RON2 complexes. Principally, TgAMA4 lacks both a deep surface groove and a key surface loop that have been established to govern RON2 ligand binding selectivity in other AMAs. Our study reveals a previously underappreciated level of molecular diversity at the parasite–host-cell interface and offers intriguing insight into the adaptation strategies underlying sporozoite invasion. Moreover, our data offer the potential for improved design of neutralizing therapeutics targeting a broad range of AMA–RON2 pairs and apicomplexan invasive stages. PMID:26712012

  13. Distinct Involvement of the Gab1 and Grb2 Adaptor Proteins in Signal Transduction by the Related Receptor Tyrosine Kinases RON and MET

    PubMed Central

    Chaudhuri, Amitabha; Xie, Ming-Hong; Yang, Becky; Mahapatra, Kaushiki; Liu, Jinfeng; Marsters, Scot; Bodepudi, Sweta; Ashkenazi, Avi

    2011-01-01

    Although the signal transduction mechanisms of the receptor tyrosine kinase MET are well defined, less is known about its close relative RON. MET initiates intracellular signaling by autophosphorylation on specific cytoplasmic tyrosines that form docking sites for the adaptor proteins Grb2 and Gab1. Grb2 binds directly and is essential for all of the biological activities of MET. Gab1 docks either directly or indirectly via Grb2 and controls only a subset of MET functions. Because MET and RON possess similar adaptor binding sites, it was anticipated that their adaptor interactions would be conserved. Here we show that in contrast to MET, RON relies primarily on Gab1 for signal transmission. Surprisingly, disruption of the Grb2 docking site of RON or Grb2 depletion augments activity, whereas enhancement of Grb2 binding attenuates Gab1 recruitment and signaling. Hence, RON and MET differ in their adaptor interactions; furthermore, Grb2 performs a novel antagonistic role in the context of RON signaling. PMID:21784853

  14. Disrupting malaria parasite AMA1-RON2 interaction with a small molecule prevents erythrocyte invasion.

    PubMed

    Srinivasan, Prakash; Yasgar, Adam; Luci, Diane K; Beatty, Wandy L; Hu, Xin; Andersen, John; Narum, David L; Moch, J Kathleen; Sun, Hongmao; Haynes, J David; Maloney, David J; Jadhav, Ajit; Simeonov, Anton; Miller, Louis H

    2013-01-01

    Plasmodium falciparum resistance to artemisinin derivatives, the first-line antimalarial drug, drives the search for new classes of chemotherapeutic agents. Current discovery is primarily directed against the intracellular forms of the parasite. However, late schizont-infected red blood cells (RBCs) may still rupture and cause disease by sequestration; consequently targeting invasion may reduce disease severity. Merozoite invasion of RBCs requires interaction between two parasite proteins AMA1 and RON2. Here we identify the first inhibitor of this interaction that also blocks merozoite invasion in genetically distinct parasites by screening a library of over 21,000 compounds. We demonstrate that this inhibition is mediated by the small molecule binding to AMA1 and blocking the formation of AMA1-RON complex. Electron microscopy confirms that the inhibitor prevents junction formation, a critical step in invasion that results from AMA1-RON2 binding. This study uncovers a strategy that will allow for highly effective combination therapies alongside existing antimalarial drugs.

  15. Thermodynamics properties and combustion performance investigation of higher chain alcohol-RON 92 gasoline system

    NASA Astrophysics Data System (ADS)

    Oktavian, Rama; Darmawan, Rhezaldian Eka; Diarahmawati, Ayu; Kartiko, Intan Dyah; Rachmawati, Rizqi Tri

    2017-03-01

    The increasing consumption of fossil fuel in Indonesia is not followed by the rising on domestic oil production. This will lead to the depletion of fossil fuel reserves that will affect the availability of energy resources. Biofuel is considered as the critical solution to solve this problem in Indonesia. In recent years, alcohol produced from biomass has been used as an oxygenated compound in gasoline to increase the octane number and reduce pollutants resulting from motor vehicle exhaust emissions. However, the use of alcohol as an additive compounds is still limited to ethanol. In fact, the use of higher-chain alcohol such as 1-butanol offers more benefits over ethanol due to its higher calorific value. 1-butanol also has good characteristics for gasoline mixture such as less corrosive than ethanol, more resistant to water contamination, its low vapor pressure which leads to more safety application. This work investigated the effect of 1-butanol addition on the thermodynamic properties of gasoline-ethanol blend, in the form of density values, isobaric expansion coefficient, and the calorific value. The addition of 1-butanol up to 15% weight (80% RON 92-5% ethanol-15% 1-butanol) gives higher density to alcohol-gasoline blend up to 2% compared with pure RON 92 gasoline. Moreover, this addition produces the calorific value of gasoline blend of 11,313 cal/gr compared to pure RON 92 gasoline with the calorific value of 12,117 cal/gram. This blend can reduce the RON 92 gasoline consumption up to 15% from calorific value perspective.

  16. STK/RON receptor tyrosine kinase mediates both apoptotic and growth signals via the multifunctional docking site conserved among the HGF receptor family.

    PubMed Central

    Iwama, A; Yamaguchi, N; Suda, T

    1996-01-01

    STK/RON tyrosine kinase, a member of the hepatocyte growth factor (HGF) receptor family, is a receptor for macrophage-stimulating protein (MSP). To examine the STK/RON signalling pathway, we generated STK/ RON transfectants showing opposite features in growth. STK/RON-expressing Ba/F3 pro-B cells (BaF/STK) exhibited MSP-dependent growth, whereas STK/ RON-expressing mouse erythroleukaemia cells (MEL/ STK) displayed MSP-induced apoptosis. This apoptosis was accompanied by the prolonged activation of c-Jun N-terminal kinase (JNK), which has recently been implicated in the initiation of apoptosis. Co-immunoprecipitation analyses showed that autophosphorylated STK/RON associated with PLC-gamma, P13-kinase, Shc and Grb2 in both transfectants. However, major tyrosine-phosphorylated proteins, p61 and p65, specifically associated with STK/RON in MEL/STK cells. Mutations at two C-terminal tyrosine residues, Y1330 and Y1337, in the counterpart of the multifunctional docking site of the HGF receptor abolished both MSP-induced growth and apoptosis. Analyses of these mutants and in vitro association revealed that signalling proteins including p61 and p65 directly bound to the phosphotyrosines in the multifunctional docking site. These results demonstrate that positive or negative signals toward cell growth are generated through the multifunctional docking site and suggest the involvement of p61 and p65 as well as JNK in apoptosis. Our findings provide the first evidence for apoptosis via a receptor tyrosine kinase. Images PMID:8918464

  17. Proposed Modification to Ron Bruns Feed Yards, Homeplace Nutrient Management Plan

    EPA Pesticide Factsheets

    Ron Bruns Feed Yards, Homeplace is a beef cattle feedlot located on the Omaha Indian Reservation, which is located about 5 miles northwest of Pender in Thurston County, Nebraska. The facility is permitted to confine a total of 3,000 head of cattle. The ter

  18. Cold atmospheric plasma jet-generated RONS and their selective effects on normal and carcinoma cells

    PubMed Central

    Kim, Sun Ja; Chung, T. H.

    2016-01-01

    Cold atmospheric helium plasma jets were fabricated and utilized for plasma–cell interactions. The effect of operating parameters and jet design on the generation of specific reactive oxygen and nitrogen species (RONS) within cells and cellular response were investigated. It was found that plasma treatment induced the overproduction of RONS in various cancer cell lines selectively. The plasma under a relatively low applied voltage induced the detachment of cells, a reduction in cell viability, and apoptosis, while the plasma under higher applied voltage led to cellular necrosis in our case. To determine whether plasma-induced reactive oxygen species (ROS) generation occurs through interfering with mitochondria-related cellular response, we examined the plasma effects on ROS generation in both parental A549 cells and A549 ρ0 cells. It was observed that cancer cells were more susceptible to plasma-induced RONS (especially nitric oxide (NO) and nitrogen dioxide (NO2−) radicals) than normal cells, and consequently, plasma induced apoptotic cell responses mainly in cancer cells. PMID:26838306

  19. Evidence for increasingly variable Palmer Drought Severity Index in the United States since 1895.

    PubMed

    Rayne, Sierra; Forest, Kaya

    2016-02-15

    Annual and summertime trends towards increasingly variable values of the Palmer Drought Severity Index (PDSI) over a sub-decadal period (five years) were investigated within the contiguous United States between 1895 and the present. For the contiguous United States as a whole, there is a significant increasing trend in the five-year running minimum-maximum ranges for the annual PDSI (aPDSI5 yr(min|max, range)). During this time frame, the average aPDSI5 yr(min|max, range) has increased by about one full unit, indicating a substantial increase in drought variability over short time scales across the United States. The end members of the running aPDSI5 yr(min|max, range) highlight even more rapid changes in the drought index variability within the past 120 years. This increasing variability in the aPDSI5 yr(min|max, range) is driven primarily by changes taking place in the Pacific and Atlantic Ocean coastal climate regions, climate regions which collectively comprise one-third the area of the contiguous United States. Similar trends were found for the annual and summertime Palmer Hydrological Drought Index (PHDI), the Palmer Modified Drought Index (PMDI), and the Palmer Z Index (PZI). Overall, interannual drought patterns in the contiguous United States are becoming more extreme and difficult to predict, posing a challenge to agricultural and other water-resource related planning efforts. Copyright © 2015 Elsevier B.V. All rights reserved.

  20. Effect of compensatory growth on Palmer amaranth response to glyphosate.

    USDA-ARS?s Scientific Manuscript database

    Incomplete weed control can occur after herbicide applications. Death of one or many shoot meristems could remove apical dominance, leading to compensatory growth from once dormant lateral buds. Palmer amaranth (PA) dieback and regrowth in response to POST herbicides has been observed. The objective...

  1. Alice Freeman Palmer: The Evolution of a New Woman.

    ERIC Educational Resources Information Center

    Bordin, Ruth

    This book presents a biographical account of the life of Alice Freeman Palmer (1855-1902) who is credited with expanding academic horizons for women in the United States during the late 19th and early 20th centuries. It tells of the obstacles she confronted as she chose both marriage and a professional career as well as illuminates this…

  2. Teaching with Documents: The Red Scare and A. Mitchell Palmer.

    ERIC Educational Resources Information Center

    Mueller, Jean; Burroughs, Wynell

    1987-01-01

    Reviews the political conditions surrounding the Red Scare following World War I. Features a June, 1920 letter from a prominent newspaper editor which supported Attorney General A. Mitchell Palmer's anti-Communist policies. Includes teaching suggestions along with a two-page reprint of the original letter. (JDH)

  3. Targeting the Ron-Dek Signaling Axis in Breast Cancer

    DTIC Science & Technology

    2015-09-01

    deficient alveolar myeloid cells exacerbate LPS-induced acute lung injury in the murine lung. Innate immunity. 2011; 17:499–507. 25. Stuart WD, Kulkarni...induced Ron activation in human and murine breast cancer cell lines induces the accumulation of Dek protein. This accumulation of Dek is significant as...Dek overexpression in breast cancer cell lines leads to increases in cell growth and migration while Dek depletion in breast cancer cells leads to

  4. A Pleistocene Clone of Palmer's Oak Persisting in Southern California

    PubMed Central

    May, Michael R.; Provance, Mitchell C.; Sanders, Andrew C.; Ellstrand, Norman C.; Ross-Ibarra, Jeffrey

    2009-01-01

    Background The distribution of Palmer's oak (Quercus palmeri Engelm.) includes numerous isolated populations that are presumably relicts of a formerly larger range that has contracted due to spreading aridity following the end of the Pleistocene. Principal Findings We investigated a recently discovered disjunct population of Palmer's oak in the Jurupa Mountains of Riverside County, California. Patterns of allozyme polymorphism, morphological homogeneity, widespread fruit abortion, and evidence of fire resprouting all strongly support the hypothesis that the population is a single clone. The size of the clone and estimates of annual growth from multiple populations lead us to conclude that the clone is in excess of 13,000 years old. Conclusions The ancient age of the clone implies it originated during the Pleistocene and is a relict of a vanished vegetation community. Range contraction after climate change best explains the modern disjunct distribution of Q. palmeri and perhaps other plants in California. PMID:20041136

  5. Quantitative Voronovskaya and Grüss-Voronovskaya type theorems for Jain-Durrmeyer operators of blending type

    NASA Astrophysics Data System (ADS)

    Kajla, Arun; Deshwal, Sheetal; Agrawal, P. N.

    2018-05-01

    In the present paper we introduce a Durrmeyer variant of Jain operators based on a function ρ (x) where ρ is a continuously differentiable function on [0,∞), ρ (0)=0 and \\inf ρ '(x)≥ a, a >0, x \\in [0,∞) . For these new operators, some indispensable auxiliary results are established first. Then, the degree of approximation with the aid of Ditzian-Totik modulus of smoothness and the rate of convergence for functions whose derivatives are of bounded variation, is obtained. Further, we focus on the study of a Voronovskaja type asymptotic theorem, quantitative Voronovskaya and Grüss-Voronovskaya type theorems.

  6. Primary productivity of the Palmer Long Term Ecological Research Area and the Southern Ocean

    NASA Astrophysics Data System (ADS)

    Smith, R. C.; Baker, K. S.; Byers, M. L.; Stammerjohn, S. E.

    1998-11-01

    A major objective of the Palmer Long Term Ecological Research (Palmer LTER) project is to obtain a comprehensive understanding of the various components of the Antarctic marine ecosystem. Phytoplankton production plays a key role in this so-called high nutrient, low chlorophyll environment, and factors that regulate production include those that control cell growth (light, temperature, and nutrients) and those that control cell accumulation rate and hence population growth (water column stability, grazing, and sinking). Sea ice mediates several of these factors and frequently conditions the water column for a spring bloom which is characterized by a pulse of production restricted in both time and space. This study models the spatial and temporal variability of primary production within the Palmer LTER area west of the Antarctic Peninsula and discusses this production in the context of historical data for the Southern Ocean. Primary production for the Southern Ocean and the Palmer LTER area have been computed using both light-pigment production models [Smith, R.C., Bidigare, R.R., Prézelin, B.B., Baker, K.S., Brooks, J.M., 1987. Optical characterization of primary productivity across a coastal front. Mar. Biol. (96), 575-591; Bidigare, R.R., Smith, R.C., Baker, K.S., Marra, J., 1987. Oceanic primary production estimates from measurements of spectral irradiance and pigment concentrations. Global Biogeochem. Cycles (1), 171-186; Morel, A., Berthon, J.F., 1989. Surface pigments, algal biomass profiles and potential production of the euphotic layer—relationships reinvestigated in view of remote-sensing applications. Limnol. Oceanogr. (34), 1545-1562] and an ice edge production model [Nelson, D.M., Smith, W.O., 1986. Phytoplankton bloom dynamics of the western Ross Sea ice edge: II. Mesoscale cycling of nitrogen and silicon. Deep-Sea Res. (33), 1389-1412; Wilson, D.L., Smith, W.O., Nelson, D.M., 1986. Phytoplankton bloom dynamics of the Western Ross Sea ice edge: I

  7. Genetic sampling of Palmer's chipmunks in the Spring Mountains, Nevada

    Treesearch

    Kevin S. McKelvey; Jennifer E. Ramirez; Kristine L. Pilgrim; Samuel A. Cushman; Michael K. Schwartz

    2013-01-01

    Palmer's chipmunk (Neotamias palmeri) is a medium-sized chipmunk whose range is limited to the higher-elevation areas of the Spring Mountain Range, Nevada. A second chipmunk species, the Panamint chipmunk (Neotamias panamintinus), is more broadly distributed and lives in lower-elevation, primarily pinyon-juniper (Pinus monophylla-Juniperus osteosperma) habitat...

  8. Potential geographic distribution of Palmer amaranth under current and future climates

    USDA-ARS?s Scientific Manuscript database

    Herbicide resistant weeds are increasingly becoming a major challenge for agricultural production worldwide. Palmer amaranth is an invasive annual forb that has recently emerged as one of the most widespread and severe agronomic weeds in the US, due in part to its facility for evolving herbicide res...

  9. Increased ice flow in Western Palmer Land linked to ocean melting

    NASA Astrophysics Data System (ADS)

    Hogg, Anna E.; Shepherd, Andrew; Cornford, Stephen L.; Briggs, Kate H.; Gourmelen, Noel; Graham, Jennifer A.; Joughin, Ian; Mouginot, Jeremie; Nagler, Thomas; Payne, Antony J.; Rignot, Eric; Wuite, Jan

    2017-05-01

    A decrease in the mass and volume of Western Palmer Land has raised the prospect that ice speed has increased in this marine-based sector of Antarctica. To assess this possibility, we measure ice velocity over 25 years using satellite imagery and an optimized modeling approach. More than 30 unnamed outlet glaciers drain the 800 km coastline of Western Palmer Land at speeds ranging from 0.5 to 2.5 m/d, interspersed with near-stagnant ice. Between 1992 and 2015, most of the outlet glaciers sped up by 0.2 to 0.3 m/d, leading to a 13% increase in ice flow and a 15 km3/yr increase in ice discharge across the sector as a whole. Speedup is greatest where glaciers are grounded more than 300 m below sea level, consistent with a loss of buttressing caused by ice shelf thinning in a region of shoaling warm circumpolar water.

  10. Hazardous Waste Cleanup: GE Residential Products Incorporated in Palmer Ward, Puerto Rico

    EPA Pesticide Factsheets

    The GE Residential Products, Inc., former Caribe General Electric Products, Inc. (Caribe GE) is an electro-plating facility, located in Palmer Ward, Municipality of Rio Grande, Commonwealth of Puerto Rico. The facility is located on both sides of State

  11. Volney B. Palmer, 1799-1864: The Nation's First Advertising Agency Man.

    ERIC Educational Resources Information Center

    Holland, Donald R.

    This monograph examines the life of Volney B. Palmer, who was the prototype of the modern advertising person. The first section discusses his background and early experience in Pennsylvania. The second section discusses the American Newspaper Agency, established as the first advertising agency in 1842. The third section examines the kind of man…

  12. Project CONVERGE: Initial Results From the Mapping of Surface Currents in Palmer Deep

    NASA Astrophysics Data System (ADS)

    Statscewich, H.; Kohut, J. T.; Winsor, P.; Oliver, M. J.; Bernard, K. S.; Cimino, M. A.; Fraser, W.

    2016-02-01

    The Palmer Deep submarine canyon on the Western Antarctic Peninsula provides a conduit for upwelling of relatively warm, nutrient rich waters which enhance local primary production and support a food web productive enough to sustain a large top predator biomass. In an analysis of ten years of satellite-tagged penguins, Oliver et al. (2013) showed that circulation features associated with tidal flows may be a key driver of nearshore predator distributions. During diurnal tides, the penguins feed close to their breeding colonies and during semi-diurnal tides, the penguins make foraging trips to the more distant regions of Palmer Deep. It is hypothesized that convergent features act to concentrate primary producers and aggregate schools of krill that influence the behavior of predator species. The initial results from a six month deployment of a High Frequency Radar network in Palmer Deep are presented in an attempt to characterize and quantify convergent features. During a three month period from January through March 2015, we conducted in situ sampling consisting of multiple underwater glider deployments, small boat acoustic surveys of Antarctic krill, and penguin ARGOS-linked satellite telemetry and time-depth recorders (TDRs). The combination of real-time surface current maps with adaptive in situ sampling introduces High Frequency Radar to the Antarctic in a way that allows us to rigorously and efficiently test the influence of local tidal processes on top predator foraging ecology.

  13. Dietary intake of total and inorganic arsenic by adults in arsenic-contaminated area of Ron Phibun district, Thailand.

    PubMed

    Ruangwises, Suthep; Saipan, Piyawat

    2010-03-01

    Ron Phibun District, approximately 800 km south of Bangkok, is the site of tin mines operated almost 100 years ago. As a result of mining activities, arsenic contaminated the soil and groundwater of the district. The specific aim of this study was to estimate the dietary intakes of total and inorganic arsenic in 20 adults (10 males and 10 females) residing in Ron Phibun District by a duplicate food approach for 7-consecutive days. The weekly intake rates of inorganic arsenic ranged from 5.54 to 13.3 microg/kg BW for males and 6.11-12.1 microg/kg BW for females.

  14. Sex differences in the Kimchi-Palmer task revisited: Global reaction times, but not number of global choices differ between adult men and women.

    PubMed

    Scheuringer, Andrea; Pletzer, Belinda

    2016-10-15

    Research, directly assessing sex-dependent differences in global versus local processing is sparse, but predominantly suggesting that men show a stronger global processing bias than women. Utilizing the Kimchi-Palmer task however, sex differences in the number of global choices can only be found in children, but not in adults. In the current study 52 men and 46 women completed a computerized version of the Kimchi Palmer task, in order to investigate whether sex-differences in global-local processing in the Kimchi-Palmer task are reflected in choice reaction times rather than choices per se. While no sex differences were found in the number of global choices, we found that especially women are faster in making local choices than men, while men are faster in making global choices than women. We did not find support for the assumption that this sex difference was modulated by menstrual cycle phase of women, since the difference between reaction times to global and local choices was consistent across the menstrual cycle of women. Accordingly there was no relationship between progesterone and global-local processing in the Kimchi-Palmer task. However, like in studies utilizing the Navon task, testosterone was positively related to the number of global choices in both men and women. To our knowledge, this is the first study including reaction times as outcome measure in a Kimchi Palmer paradigm and also the first study demonstrating sex differences in the Kimchi Palmer task in adults. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

  15. Asteroid Lightcurve Analysis at CS3-Palmer Divide Station: 2017 October-December

    NASA Astrophysics Data System (ADS)

    Warner, Brian D.

    2018-04-01

    Lightcurves for 18 main-belt asteroids were obtained at the Center for Solar System Studies-Palmer Divide Station (CS3-PDS) from 2017 October-December. All but one of the asteroids were targets of opportunity, i.e., in the field of planned targets, which demonstrates a good reason for data mining images.

  16. Understanding Chemistry-Specific Fuel Differences at a Constant RON in a Boosted SI Engine

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Szybist, James P.; Splitter, Derek A.

    The goal of the US Department of Energy Co-Optimization of Fuels and Engines (Co-Optima) initiative is to accelerate the development of advanced fuels and engines for higher efficiency and lower emissions. A guiding principle of this initiative is the central fuel properties hypothesis (CFPH), which states that fuel properties provide an indication of a fuel’s performance, regardless of its chemical composition. This is an important consideration for Co-Optima because many of the fuels under consideration are from bio-derived sources with chemical compositions that are unconventional relative to petroleum-derived gasoline or ethanol. In this study, we investigated a total of sevenmore » fuels in a spark ignition engine under boosted operating conditions to determine whether knock propensity is predicted by fuel antiknock metrics: antiknock index (AKI), research octane number (RON), and octane index (OI). Six of these fuels have a constant RON value but otherwise represent a wide range of fuel properties and chemistry. Consistent with previous studies, we found that OI was a much better predictor of knock propensity that either AKI or RON. However, we also found that there were significant fuel-specific deviations from the OI predictions. Combustion analysis provided insight that fuel kinetic complexities, including the presence of pre-spark heat release, likely limits the ability of standardized tests and metrics to accurately predict knocking tendency at all operating conditions. While limitations of OI were revealed in this study, we found that fuels with unconventional chemistry, in particular esters and ethers, behaved in accordance with CFPH as well as petroleum-derived fuels.« less

  17. Understanding Chemistry-Specific Fuel Differences at a Constant RON in a Boosted SI Engine

    DOE PAGES

    Szybist, James P.; Splitter, Derek A.

    2018-01-02

    The goal of the US Department of Energy Co-Optimization of Fuels and Engines (Co-Optima) initiative is to accelerate the development of advanced fuels and engines for higher efficiency and lower emissions. A guiding principle of this initiative is the central fuel properties hypothesis (CFPH), which states that fuel properties provide an indication of a fuel’s performance, regardless of its chemical composition. This is an important consideration for Co-Optima because many of the fuels under consideration are from bio-derived sources with chemical compositions that are unconventional relative to petroleum-derived gasoline or ethanol. In this study, we investigated a total of sevenmore » fuels in a spark ignition engine under boosted operating conditions to determine whether knock propensity is predicted by fuel antiknock metrics: antiknock index (AKI), research octane number (RON), and octane index (OI). Six of these fuels have a constant RON value but otherwise represent a wide range of fuel properties and chemistry. Consistent with previous studies, we found that OI was a much better predictor of knock propensity that either AKI or RON. However, we also found that there were significant fuel-specific deviations from the OI predictions. Combustion analysis provided insight that fuel kinetic complexities, including the presence of pre-spark heat release, likely limits the ability of standardized tests and metrics to accurately predict knocking tendency at all operating conditions. While limitations of OI were revealed in this study, we found that fuels with unconventional chemistry, in particular esters and ethers, behaved in accordance with CFPH as well as petroleum-derived fuels.« less

  18. Monoclonal antibody Zt/g4 targeting RON receptor tyrosine kinase enhances chemosensitivity of bladder cancer cells to Epirubicin by promoting G1/S arrest and apoptosis.

    PubMed

    Chen, Jun-Feng; Yu, Bi-Xia; Yu, Rui; Ma, Liang; Lv, Xiu-Yi; Cheng, Yue; Ma, Qi

    2017-02-01

    Epirubicin (EPI) is one of the most used intravesical chemotherapy agents after transurethral resection to non-muscle invasive bladder tumors (NMIBC) to prevent cancer recurrence and progression. However, even after resection of bladder tumors and intravesical chemotherapy, half of them will recur and progress. RON is a membrane tyrosine kinase receptor usually overexpressed in bladder cancer cells and associated with poor pathological features. This study aims to investigate the effects of anti-RON monoclonal antibody Zt/g4 on the chemosensitivity of bladder cells to EPI. After Zt/g4 treatment, cell cytotoxicity was significantly increased and cell invasion was markedly suppressed in EPI-treated bladder cancer cells. Further investigation indicated that combing Zt/g4 with EPI promoted cell G1/S-phase arrest and apoptosis, which are the potential mechanisms that RON signaling inhibition enhances chemosensitivity of EPI. Thus, combing antibody-based RON targeted therapy enhances the therapeutic effects of intravesical chemotherapy, which provides new strategy for further improvement of NMIBC patient outcomes.

  19. Computational and biophysical approaches to protein-protein interaction inhibition of Plasmodium falciparum AMA1/RON2 complex

    NASA Astrophysics Data System (ADS)

    Pihan, Emilie; Delgadillo, Roberto F.; Tonkin, Michelle L.; Pugnière, Martine; Lebrun, Maryse; Boulanger, Martin J.; Douguet, Dominique

    2015-06-01

    Invasion of the red blood cell by Plasmodium falciparum parasites requires formation of an electron dense circumferential ring called the Moving Junction (MJ). The MJ is anchored by a high affinity complex of two parasite proteins: Apical Membrane Antigen 1 ( PfAMA1) displayed on the surface of the parasite and Rhoptry Neck Protein 2 that is discharged from the parasite and imbedded in the membrane of the host cell. Structural studies of PfAMA1 revealed a conserved hydrophobic groove localized to the apical surface that coordinates RON2 and invasion inhibitory peptides. In the present work, we employed computational and biophysical methods to identify competitive P. falciparum AMA1-RON2 inhibitors with the goal of exploring the `druggability' of this attractive antimalarial target. A virtual screen followed by molecular docking with the PfAMA1 crystal structure was performed using an eight million compound collection that included commercial molecules, the ChEMBL malaria library and approved drugs. The consensus approach resulted in the selection of inhibitor candidates. We also developed a fluorescence anisotropy assay using a modified inhibitory peptide to experimentally validate the ability of the selected compounds to inhibit the AMA1-RON2 interaction. Among those, we identified one compound that displayed significant inhibition. This study offers interesting clues to improve the throughput and reliability of screening for new drug leads.

  20. Comparison of catalytic converter performance in internal combustion engine fueled with Ron 95 and Ron 97 gasoline

    NASA Astrophysics Data System (ADS)

    Leman, A. M.; Rahman, Fakhrurrazi; Jajuli, Afiqah; Feriyanto, Dafit; Zakaria, Supaat

    2017-09-01

    Generating ideal stability between engine performance, fuel consumption and emission is one of the main challenges in the automotive industry. The characteristics of engine combustion and creation of emission might simply change with different types of operating parameters. This study aims in investigating the relationship between two types of fuels on the performance and exhaust emission of internal combustion engine using ceramic and metallic catalytic converters. Experimental tests were performed on Mitsubishi 4G93 engine by applying several ranges of engine speeds to determine the conversion of pollutant gases released by the engine. The obtained results specify that the usage of RON 97 equipped with metallic converters might increase the conversion percentage of 1.31% for CO and 126 ppm of HC gases. The metallic converters can perform higher conversion compared to ceramic because in the high space velocities, metallic has higher surface geometry area and higher amount of transverse Peclet number (Pi). Ceramic converters achieved conversion at 2496 ppm of NOx gas, which is higher than the metallic converter.

  1. Asteroid Lightcurve Analysis at CS3-Palmer Divide Station: 2017 July Through October

    NASA Astrophysics Data System (ADS)

    Warner, Brian D.

    2018-01-01

    Lightcurves for 17 main-belt asteroids were obtained at the Center for Solar System Studies-Palmer Divide Station (CS3-PDS) from 2017 July through October. All but two of the asteroids were targets of opportunity, i.e., in the field of planned targets, demonstrating a good reason for data mining images.

  2. Integrated palmer amaranth management in glufosinate-resistant cotton: II. primary, secondary, and conservation tillage

    USDA-ARS?s Scientific Manuscript database

    A three-year field experiment was conducted to evaluate the role of inversion tillage, cover crops and spring tillage methods for Palmer amaranth between-row (BR) and within-row (WR) management in glufosinate-resistant cotton. Main plots were two inversion tillage systems: fall inversion tillage (IT...

  3. Ron Leuschner donates over 11,000 specimens of Pyraloidea to the National Museum of Natural History

    USDA-ARS?s Scientific Manuscript database

    Ron Leuschner, Past President of the Lepidopterists’ Society, donated over 11,000 specimens of the Pyraloidea to the National Museum of Natural History, Smithsonian Institution, Washington, DC. This collection is strongly represented by specimens from the western United States and may prove to be on...

  4. Exploring the Components of the Palmer Drought Indices Using the Apalachicola-Chattahoochee-Flint (ACF) River Basin as a Case Study

    NASA Astrophysics Data System (ADS)

    Perrone, D.; Duncan, L. L.; Jacobi, J. H.; Hornberger, G.

    2012-12-01

    Water resources are vital to sustaining ecosystem services, energy and food supplies, and industrial processes. Competition for water resources is likely to intensify as the population increases, economy grows, and land develops. Drought events intensify water scarcity, and recent events in many countries, including the United States (US), Great Britain, and Sri Lanka, highlight how important it is to provide meaningful context to water planners and managers. Palmer's drought indices - Z Index, Palmer Drought Severity Index (PDSI), and Palmer Hydrological Drought Index (PHDI) - are widely used and accepted by scientists and policy makers in the US to understand drought and manage water resources. Drought index values at the climate division scale are available, but a transparent calculation tool at multiple spatial and temporal scales is not readily available. Moreover, a close look at the development of the indices reveals a number of subjective calculation methods and regionally biased factors. For researchers studying areas with overlapping climate divisions, performing international research, or working with limited, site-specific data, the ability to control and modify calculations is desired. This research presents a transparent tool for calculating Palmer's drought indices. We use the Apalachicola-Chattahoochee-Flint (ACF) River Basin, located in the southeastern US, as our case study to explore and evaluate the sensitivity of Palmer's indices to temperature and precipitation anomalies, calibration periods, and other index components. The ACF has suffered two major droughts (2007 and 2012) in the past five years and supports multiple demand-side sectors - agriculture in Georgia, public and recreational supply for the Atlanta metropolitan area, hydroelectric power in Alabama, tri-state navigation, and ecosystem services. We show how the PDSI varies in response to changes in precipitation, calibration period, and a number of other variables. The aim of the

  5. Apollo, Paintbrushes, and Packaging: An Interview with 40-Year Spacesuit Veteran Ron Woods

    NASA Technical Reports Server (NTRS)

    Woods, Ron

    2012-01-01

    Ron Woods exhibits a wealth of knowledge gathered in more than 40 years of experience with NASA and spacesuits. Many people are interested in his biography, progression of work at NASA, impact on the U.S. Spacesuit, and career accomplishments. Wright, from the JSC History Office, conducted this personal background interview with Woods. The interview highlighted the influences and decision-making methods that impacted his technical and management contributions to the space program.

  6. Asteroid Lightcurve Analysis at CS3-Palmer Divide Station: 2017 April thru June

    NASA Astrophysics Data System (ADS)

    Warner, Brian D.

    2017-10-01

    Lightcurves for 16 main-belt asteroids were obtained at the Center for Solar System Studies-Palmer Divide Station (CS3-PDS) from 2017 April thru June. Many of the asteroids were “strays” in the field of planned targets, demonstrating a good reason for data mining images. Analysis shows that the Hungaria asteroid (45878) 2000 WX29 may be binary.

  7. Asteroid Lightcurve Analysis at the Palmer Divide Observatory - September-December 2006

    NASA Astrophysics Data System (ADS)

    Warner, Brian D.

    2007-06-01

    Lightcurves for 25 asteroids were obtained at the Palmer Divide Observatory from late September through December 2006: 143 Adria, 469 Argentina, 595 Polyxena, 880 Herba, 1515 Perrotin, 1756 Giacobini, 1920 Sarmiento, 2645 Daphne Plane, 2793 Valdaj, 4125 Lew Allen, 4142 Derzu-Uzala, 4690 Strasbourg, 4860 Gubbio, 6794 Masuisakura, (10171) 1995 EE8, 13025 Zurich, (15786) 1993 RS, 17681 Tweedledum, (24827) 1995 RA, (30019) 2000 DD, (31180) 1997 YX3, (31354) 1998 TR3, (32814) 1990 XZ, (34817) 2001 SE116, and 2006 WH1.

  8. Asteroid Lightcurve Analysis at the Palmer Divide Observatory: September-December 2007

    NASA Astrophysics Data System (ADS)

    Warner, Brian D.

    2008-06-01

    Lightcurves for 20 asteroids were obtained at the Palmer Divide Observatory from September-December 2007. 167 Urda; 793 Arizona; 1112 Polonia; 1325 Inanda; 1590 Tsiolkovskaja; 1741 Giclas; 2347 Vinata; 4464 Vulcano; 5720 Halweaver; 7086 Bopp; 7187 Isobe; (8309) 1996 NL1; (10496) 1986 RK; (11904) 1991 TR1; (17738) 1998 BS15; (20936) 4835 T-1; (25332) 1999 KK6; (31793) 1999 LB6; (44892) 1999 VJ8; (52314) 1991 XD. In addition, previously unpublished results from 2000 for (10936) 1998 FN11 are reported.

  9. Overlapping Residual Herbicides for Control of Photosystem (PS) II- and 4-Hydroxyphenylpyruvate Dioxygenase (HPPD)-Inhibitor-Resistant Palmer amaranth (Amaranthus palmeri S. Watson) in Glyphosate-Resistant Maize

    PubMed Central

    Chahal, Parminder S.; Ganie, Zahoor A.; Jhala, Amit J.

    2018-01-01

    A Palmer amaranth (Amaranthus palmeri S. Watson) biotype has evolved resistance to photosystem (PS) II- (atrazine) and 4-hydroxyphenylpyruvate dioxygenase (HPPD)-inhibiting herbicides (mesotrione, tembotrione, and topramezone) in maize seed production field in Nebraska, USA. The objectives of this study were to determine the effect of soil residual pre-emergence (PRE) herbicides followed by (fb) tank-mixture of residual and foliar active post-emergence (POST) herbicides on PS-II- and HPPD-inhibitor-resistant Palmer amaranth control, maize yield, and net economic returns. Field experiments were conducted in a grower's field infested with PS II- and HPPD-inhibitor-resistant Palmer amaranth near Shickley in Fillmore County, Nebraska, USA in 2015 and 2016. The contrast analysis suggested that saflufenacil plus dimethenamid-P or pyroxasulfone plus saflufenacil applied PRE provided 80–82% Palmer amaranth control compared to 65 and 39% control with saflufenacil and pyroxasulfone applied alone at 3 weeks after PRE (WAPRE), respectively. Among the PRE fb POST herbicide programs, 95–98% Palmer amaranth control was achieved with pyroxasulfone plus safluefenacil, or saflufenacil plus dimethenamid-P applied PRE, fb glyphosate plus topramezone plus dimethenamid-P plus atrazine, glyphosate plus diflufenzopyr plus dicamba plus pyroxasulfone, glyphosate plus diflufenzopyr plus pendimethalin, or glyphosate plus diflufenzopyr plus dicamba plus atrazine applied POST at 3 weeks after POST (WAPOST) through maize harvest. Based on contrast analysis, PRE fb POST programs provided 77–83% Palmer amaranth control at 3 WAPOST through maize harvest compared to 12–15% control with PRE-only and 66–84% control with POST-only programs. Similarly, PRE fb POST programs provided 99% biomass reduction at 6 WAPOST compared to PRE-only (28%) and POST-only (87%) programs. PRE fb POST programs provided higher maize yield (13,617 kg ha−1) and net return (US $1,724 ha−1) compared to the PRE

  10. Employing canopy hyperspectral narrowband data and random forest algorithm to differentiate palmer amaranth from colored cotton

    USDA-ARS?s Scientific Manuscript database

    Palmer amaranth (Amaranthus palmeri S. Wats.) invasion negatively impacts cotton (Gossypium hirsutum L.) production systems throughout the United States. The objective of this study was to evaluate canopy hyperspectral narrowband data as input into the random forest machine learning algorithm to dis...

  11. STS-131/19A Flight Control Team in FCR-1 - Orbit 1- Flight Director Ron Spencer

    NASA Image and Video Library

    2010-04-14

    JSC2010-E-052008 (14 April 2010) --- The members of the STS-131/19A ISS Orbit 2 flight control team pose for a group portrait in the space station flight control room in the Mission Control Center at NASA's Johnson Space Center. Flight director Ron Spencer (right) holds the STS-131 mission logo.

  12. Asteroid Lightcurve Analysis at CS3-Palmer Divide Station: 2016 December thru 2017 March

    NASA Astrophysics Data System (ADS)

    Warner, Brian D.

    2017-07-01

    Lightcurves for 18 main-belt asteroids were obtained at the Center for Solar System Studies-Palmer Divide Station (CS3-PDS) from 2016 December thru 2017 March. Many of the asteroids were “strays” in the field of planned targets, demonstrating a good reason for data mining images. Analysis shows that the Hungaria asteroid (45878) 2000 WX29 may be binary.

  13. Straight talk with... Carolyn Bertozzi. Interview by Roxanne Palmer.

    PubMed

    Bertozzi, Carolyn

    2010-07-01

    Last month, Carolyn Bertozzi became the first woman to win the prestigious Massachusetts Institute of Technology (MIT)-Lemelson Prize, a $500,000 award that honors midcareer inventors. Bertozzi, a chemical biologist, works to understand how sugars mediate cell-to-cell communication. But she isn't content with just observing the process; her lab at the University of California-Berkeley has pioneered tools for labeling molecules inside living cells. Her biomedical inventions have contributed to the development of noninvasive methods for identifying disease tissue within the body-advances that could revolutionize both the diagnosis and the treatment of a host of diseases ranging from arthritis to cancer. Roxanne Palmer recently caught up with her by phone to discuss Bertozzi's sweet success with cell surface sugars.

  14. Inversion tillage, high residue covers, and different herbicide regimes for palmer amaranth control in liberty link systems

    USDA-ARS?s Scientific Manuscript database

    Glyphosate-resistant Palmer amaranth is adversely affecting cotton production in the Southeast US. A field experiment was established in fall 2008 at the E.V. Smith Research Center, Field Crops Unit near Shorter, AL, to investigate the role of inversion tillage, high residue cover crops, and differ...

  15. Numerical simulation of the generation of reactive oxygen and nitrogen species (RONS) in water by atmospheric-pressure plasmas and their effects on Escherichia coli (E. coli)

    NASA Astrophysics Data System (ADS)

    Ikuse, Kazumasa; Hamaguchi, Satoshi

    2016-09-01

    We have used two types of numerical simulations to examine biological effects of reactive oxygen and nitrogen species (RONS) generated in water by an atmospheric-pressure plasma (APP) that irradiates the water surface. One is numerical simulation for the generation and transport of RONS in water based on the reaction-diffusion-advection equations coupled with Poisson equation. The rate constants, mobilities, and diffusion coefficients used in the equations are obtained from the literature. The gaseous species are given as boundary conditions and time evolution of the concentrations of chemical species in pure water is solved numerically as functions of the depth in one dimension. Although it is not clear how living organisms respond to such exogenous RONS, we also use numerical simulation for metabolic reactions of Escherichia coli (E. coli) and examine possible effects of such RONS on an in-silico model organism. The computation model is based on the flux balance analysis (FBA), where the fluxes of the metabolites in a biological system are evaluated in steady state, i.e., under the assumption that the fluxes do not change in time. The fluxes are determined with liner programming to maximize the growth rate of the bacteria under the given conditions. Although FBA cannot be directly applied to dynamical responses of metabolic reactions, the simulation still gives insight into the biological reactions to exogenous chemical species generated by an APP. Partially supported by JSPS Grants-in-Aid for Scientific Research.

  16. Construction of prediction intervals for Palmer Drought Severity Index using bootstrap

    NASA Astrophysics Data System (ADS)

    Beyaztas, Ufuk; Bickici Arikan, Bugrayhan; Beyaztas, Beste Hamiye; Kahya, Ercan

    2018-04-01

    In this study, we propose an approach based on the residual-based bootstrap method to obtain valid prediction intervals using monthly, short-term (three-months) and mid-term (six-months) drought observations. The effects of North Atlantic and Arctic Oscillation indexes on the constructed prediction intervals are also examined. Performance of the proposed approach is evaluated for the Palmer Drought Severity Index (PDSI) obtained from Konya closed basin located in Central Anatolia, Turkey. The finite sample properties of the proposed method are further illustrated by an extensive simulation study. Our results revealed that the proposed approach is capable of producing valid prediction intervals for future PDSI values.

  17. Comparing the Palmer Drought Index and the Standardized Precipitation Index for Zagreb Gric Observatory

    NASA Astrophysics Data System (ADS)

    Pandzic, K.; Likso, T.

    2012-04-01

    Conventional Palmer Drought Index (PDI) and recent Standardized Precipitation Index (SPI) for Zagreb Gric Observatory are compared by spectral analysis technique. Data for a period 1862-2010 are used. The results indicate that SPI is simpler for interpretation but PDI more comprehensive index. On the other side, lack of temperature within SPI, make impossible application of it on climate change interpretation. Possible applications of them in irrigation scheduling system is considered as well for drought risk assessment.

  18. Asteroid Lightcurve Analysis at the Palmer Divide Observatory: 2008 December - 2009 March

    NASA Astrophysics Data System (ADS)

    Warner, Brian D.

    2009-07-01

    Lightcurves for 34 asteroids were obtained at the Palmer Divide Observatory from 2008 December through 2009 March: 91 Aegina, 261 Prymno, 359 Georgia, 402 Chloe, 497 Iva, 506 Marion, 660 Crescentia, 691 Lehigh, 731 Sorga, 779 Nina, 802 Epyaxa, 908 Buda, 1015 Christa, 1518 Rovaniemi, 1600 Vyssotsky, 1656 Suomi, 2000 Herschel, 2735 Ellen, 3169 Ostro, 3854 George, 3940 Larion, (5558) 1989 WL2, (5747) 1991 CO3, 6517 Buzzi, (11304) 1993 DJ, (22195) 3509 P-L, (26383) 1999 MA2, (29780) 1999 CJ50, (45878) 2000 WX29, (45898) 2000 XQ49, (76800) 2000 OQ35, (76929) 2001 AX34, (87343) 2000 QH25, and (207398) 2006 AS2.

  19. Asteroid Lightcurve Analysis at the Palmer Divide Observatory: 2011 June - September

    NASA Astrophysics Data System (ADS)

    Warner, Brian D.

    2012-01-01

    Lightcurves for 28 asteroids were obtained at the Palmer Divide Observatory (PDO) from 2011 June to September: 903 Nealley, 1103 Sequoia, 2052 Tamriko, 2083 Smither, 2150 Nyctimene, 2272 Montezuma, 2306 Bauschinger, 4125 Lew Allen, 5571 Lesliegreen, (7660) 1993 VM1, 7933 Magritte, (16256) 2000 JM2, (16959) 1998 QE17, (17822) 1998 FM135, (18890) 2000 EV26, (27568) 2000 PT6, (31898) 2000 GC1, (32953) 1996 GF19, (32928) 1995 QZ, (33356) 1999 AM3, (35055) 1984 RB, (54234) 2000 JD16, (60365) 2000 AT109, (62117) 2000 RC102, (67404) 2000 PG26, 70030 Margaretmiller, (140428) 2001 TT94, (282081) 2000 NG. Observations of 70030 Margaretmiller indicate that the asteroid is a probable binary with a secondary period being detected but no mutual events.

  20. Seeing Double Old and New: Observations and Lightcurve Analysis at the Palmer Divide Observatory of Six Binary Asteroids

    NASA Astrophysics Data System (ADS)

    Warner, Brian D.

    2013-04-01

    Results of the analysis of lightcurves of six binary asteroids obtained at the Palmer Divide Observatory are reported. Of the six, three were previously known to be binary: 9069 Hovland, (26471) 2000 AS152, and 1994 XD. The remaining three are new confirmed or probable binary discoveries made at PDO: 2047 Smetana, (5646) 1990 TR, and (52316) 1992 BD.

  1. Relationship Between Palmer's Drought Severity Index and the Moisture Index of Woody Debris in the Southern Coastal Plain

    Treesearch

    James D. Haywood; Richard H. Stagg; Allan E. Tiarks

    2004-01-01

    After the 1998 through 2000 drought in Louisiana, some prescribed burns had uncommonly severe fire behavior. A significant portion of the consumed fuels most likely were larger material normally unavailable for burning. Therefore at sites in Louisiana, Mississippi, and Texas, we studied the relationship between Palmer’s Drought Severity Index (PDSI) and the drying rate...

  2. Did American social and economic events from 1865 to 1898 influence D.D. Palmer the chiropractor and entrepreneur?

    PubMed

    Batinić, Josip; Skowron, Mirek; Hammerich, Karin

    2013-09-01

    This paper explores how the social landscape of the latter half of the nineteenth century influenced D. D. Palmer and the many occupations he pursued. It focuses on the geographical area where D. D. lived from 1865 to 1898. This paper will show how the American social and economic events of the time provided favourable circumstances for D.D.'s entrepreneurial successes.

  3. The Courage to Teach: Exploring the Inner Landscape of a Teacher's Life (by Parker J. Palmer)

    NASA Astrophysics Data System (ADS)

    Hurt Middlecamp, Reviewed By Catherine

    1999-12-01

    Most of us would willingly - perhaps even passionately - tackle the question of what we should teach our students. Similarly, we are likely to engage in a conversation about how we teach and our preferences for organizing classroom time and structures. Although the question of why we teach may be raised less often (and perhaps with a hint of sarcasm), this too is a question to which most can offer a thoughtful response. An entirely different matter, however, is the question of who is the person teaching. This who involves the inner realms of one's heart, mind, and soul. How does our identity affect the teaching and learning processes? As we teach, what paths are we following intellectually, emotionally, or even spiritually? How do these paths influence our relationship to our content and to our students? With an engaging honesty, Parker Palmer pursues these questions in The Courage to Teach: Exploring the Inner Landscape of A Teacher's Life. At the outset he points out (p 4): I have no quarrel with the what or how or why questions - except when they are posed as the only questions worth asking. All of them can yield important insights into teaching and learning. But none of them opens up the territory I want to explore in this book: the inner landscape of the teaching self. One might well question why those of us teaching chemistry should be interested in examining ourselves as part of the teaching equation. Isn't scientific knowledge supposed to be as objective as we can make it? Isn't it better for us to check our emotional or intellectual baggage at the classroom door, rather than to taint the content with our biases? Or perhaps more directly stated, is it not more practical and a better use of our time to simply deal with the realities of the day-to-day classroom issues? Admittedly these are fair questions. However, to become stuck on them is to miss the opportunities for reflection and growth as teachers that Palmer's book offers. Simply put, people teach

  4. Did American social and economic events from 1865 to 1898 influence D.D. Palmer the chiropractor and entrepreneur?

    PubMed Central

    Batinić, Josip; Skowron, Mirek; Hammerich, Karin

    2013-01-01

    This paper explores how the social landscape of the latter half of the nineteenth century influenced D. D. Palmer and the many occupations he pursued. It focuses on the geographical area where D. D. lived from 1865 to 1898. This paper will show how the American social and economic events of the time provided favourable circumstances for D.D.’s entrepreneurial successes. PMID:23997248

  5. High residue cover crops alone or with strategic tillage to manage glyphosate-resistant palmer amaranth (amaranthus palmeri) in Southeastern cotton (gossypium hirsutum)

    USDA-ARS?s Scientific Manuscript database

    Glyphosate-resistant (GR) Palmer amaranth (Amaranthus palmeri S. Wats) is redefining row crop weed management in the Southeast due to its widespread distribution, high competitive ability, copious seed production, and resilience to standard weed management programs. Herbicides alone are failing to p...

  6. High-resolution 3 T MRI of traumatic and degenerative triangular fibrocartilage complex (TFCC) abnormalities using Palmer and Outerbridge classifications.

    PubMed

    Nozaki, T; Rafijah, G; Yang, L; Ueno, T; Horiuchi, S; Hitt, D; Yoshioka, H

    2017-10-01

    To investigate the usefulness of high-resolution 3 T magnetic resonance imaging (MRI) for the evaluation of traumatic and degenerative triangular fibrocartilage complex (TFCC) abnormalities among three groups: patients presenting with wrist pain who were (a) younger than age 50 years or (b) age 50 or older (PT<50 and PT≥50, respectively), and (c) asymptomatic controls who were younger than age 50 years (AC). High-resolution 3 T MRI was evaluated retrospectively in 96 patients, including 47 PT<50, 38 PT≥50, and 11 AC. Two board-certified radiologists reviewed the MRI images independently. MRI features of TFCC injury were analysed according to the Palmer classification, and cartilage degeneration around the TFCC was evaluated using the Outerbridge classification. Differences in MRI findings among these groups were detected using chi-square test. Cohen's kappa was calculated to assess interobserver and intra-observer reliability. The incidence of Palmer class 1A, 1C and 1D traumatic TFCC injury was significantly (p<0.05) higher in PT≥50 than in PT<50 (class 1A: 47.4% versus 27.7%, class 1C: 31.6% versus 12.8%, and class 1D: 21.1% versus 2.1%). Likewise, MRI findings of TFCC degeneration were observed more frequently in PT≥50 than in PT<50 (p<0.01). Outerbridge grade 2 or higher cartilage degeneration was significantly (p<0.01) more frequently seen in PT≥50 than in PT<50 (55.3% versus 17% in the lunate, 28.9% versus 4.3% in the triquetrum, 73.7% versus 12.8% in the ulna). High-resolution wrist MRI at 3 T enables detailed evaluation of TFCC traumatic injury and degenerative changes using the Palmer and Outerbridge classifications, with good or excellent interobserver and intra-observer reliability. Copyright © 2017 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.

  7. First confirmation and characterization of target and non-target site resistance to glyphosate in Palmer amaranth (Amaranthus palmeri) from Mexico.

    PubMed

    Dominguez-Valenzuela, Jose Alfredo; Gherekhloo, Javid; Fernández-Moreno, Pablo Tomás; Cruz-Hipolito, Hugo Enrique; Alcántara-de la Cruz, Ricardo; Sánchez-González, Eduardo; De Prado, Rafael

    2017-06-01

    Following the introduction of glyphosate-resistant (GR)-cotton crops in Mexico, farmers have relied upon glyphosate as being the only herbicide for in-season weed control. Continuous use of glyphosate within the same year and over multiple successive years has resulted in the selection of glyphosate resistance in Palmer amaranth (Amarantus palmeri). Dose-response assays confirmed resistance in seven different accessions. The resistance ratio based on GR 50 values (50% growth reduction) varied between 12 and 83. At 1000 μM glyphosate, shikimic acid accumulation in the S-accession was 30- to 2-fold higher at compared to R-accessions. At 96 h after treatment, 35-44% and 61% of applied 14 C-glyphosate was taken up by leaves of plants from R- and S-accessions, respectively. At this time, a significantly higher proportion of the glyphosate absorbed remained in the treated leaf of R-plants (55-69%) compared to S-plants (36%). Glyphosate metabolism was low and did not differ between resistant and susceptible plants. Glyphosate was differentially metabolized to AMPA and glyoxylate in plants of R- and S-accessions, although it was low in both accessions (<10%). There were differences in 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) enzyme activity by 50% (I 50 ) between R- and S-accessions. However, no significant differences were found in the basal EPSPS activity (μmol inorganic phosphate μg -1 total soluble protein min -1 ) between R- and S-accessions. A point mutation Pro-106-Ser was evidenced in three accessions. The results confirmed the resistance of Palmer amaranth accessions to glyphosate collected from GR-cotton crops from Mexico. This is the first study demonstrating glyphosate-resistance in Palmer amaranth from Mexico. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  8. Not a Simple Tether: Binding of Toxoplasma gondii AMA1 to RON2 during Invasion Protects AMA1 from Rhomboid-Mediated Cleavage and Leads to Dephosphorylation of Its Cytosolic Tail

    PubMed Central

    Krishnamurthy, Shruthi; Deng, Bin; del Rio, Roxana; Buchholz, Kerry R.; Treeck, Moritz; Urban, Siniša; Boothroyd, John; Lam, Ying-Wai

    2016-01-01

    ABSTRACT Apical membrane antigen 1 (AMA1) is a receptor protein on the surface of Toxoplasma gondii that plays a critical role in host cell invasion. The ligand to which T. gondii AMA1 (TgAMA1) binds, TgRON2, is secreted into the host cell membrane by the parasite during the early stages of invasion. The TgAMA1-TgRON2 complex forms the core of the “moving junction,” a ring-shaped zone of tight contact between the parasite and host cell membranes, through which the parasite pushes itself during invasion. Paradoxically, the parasite also expresses rhomboid proteases that constitutively cleave the TgAMA1 transmembrane domain. How can TgAMA1 function effectively in host cell binding if its extracellular domain is constantly shed from the parasite surface? We show here that when TgAMA1 binds the domain 3 (D3) peptide of TgRON2, its susceptibility to cleavage by rhomboid protease(s) is greatly reduced. This likely serves to maintain parasite-host cell binding at the moving junction, a hypothesis supported by data showing that parasites expressing a hypercleavable version of TgAMA1 invade less efficiently than wild-type parasites do. Treatment of parasites with the D3 peptide was also found to reduce phosphorylation of S527 on the cytoplasmic tail of TgAMA1, and parasites expressing a phosphomimetic S527D allele of TgAMA1 showed an invasion defect. Taken together, these data suggest that TgAMA1-TgRON2 interaction at the moving junction protects TgAMA1 molecules that are actively engaged in host cell penetration from rhomboid-mediated cleavage and generates an outside-in signal that leads to dephosphorylation of the TgAMA1 cytosolic tail. Both of these effects are required for maximally efficient host cell invasion. PMID:27624124

  9. ARC-1969-A-25541

    NASA Image and Video Library

    1959-08-04

    FLIGHT RESEARCH BRANCH PERSONNEL-1959. FRONT ROW: George Rathert, Stu Brown, Norm McFadden, Howard Turner, Gus Brunner, Venia McCloud, Violet Shaw, Kay Rizzi, Yvonne Settle, Genevieve Ziegler, Anita Palmer, Grace Carpenter, Evelyn Olson. SECOND ROW: Bill Triplett, Alan Faye, Dick Bray, Seth Anderson, Steve Belsley, Hervey Quigley, Hank Cole, Elwood Stewart, Don Higdon, Maurie White, Dorothea Wilkinson, Dick Vomaske, Stew Rolls, Mel Sadoff, Mary Thompson, Brent Creer. BACK ROW: Ron Gerdes, Joe Douvillier, John Stewart, Rod Wingrove, Walter McNeill. Note: Used in publication in Flight Research at Ames; 57 Years of Development and Validation of Aeronautical Technology NASA SP-1998-3300 fig 89

  10. Upon Further Review: V. An Examination of Previous Lightcurve Analysis from the Palmer Divide Observatory

    NASA Astrophysics Data System (ADS)

    Warner, Brian D.

    2011-01-01

    Updated results are given for nine asteroids previously reported from the Palmer Divide Observatory (PDO). The original images were re-measured to obtain new data sets using the latest version of MPO Canopus photometry software, analysis tools, and revised techniques for linking multiple observing runs covering several days to several weeks. Results that were previously not reported or were moderately different were found for 1659 Punkajarju, 1719 Jens, 1987 Kaplan, 2105 Gudy, 2961 Katsurahama, 3285 Ruth Wolfe, 3447 Burckhalter, 7816 Hanoi, and (34817) 2000 SE116. This is one in a series of papers that will examine results obtained during the initial years of the asteroid lightcurve program at PDO.

  11. Combined Palmer Type 1A and 1B Traumatic Lesions of the Triangular Fibrocartilage Complex A New Category.

    PubMed

    Nance, Erin; Ayalon, Omri; Yang, Steven

    2016-06-01

    We present a series of eight patients who underwent wrist arthroscopy for presumed solitary tears of the triangular fibrocartilage (TFC) and were, instead, found to have combined 1A (central tear) and 1B (ulnar avulsion) tears. The Palmer Classification does not currently categorize this combined pattern. All but one patient had a traumatic injury. Each subject had preoperative radiographs and MRI scans. TFC tears were evident on all MRI scans, though only one was suggestive of a combined tear pat - tern. Surgical management included arthroscopic central tear debridement and ulnar peripheral repair. Average follow-up was 22 months. Grip strength in the affected hand improved from 16% deficit as compared to the unaffected side, to 3.5% deficit postoperatively (p = 0.003), and visual analog scores (VAS) decreased from an average of 7.1/10 preoperatively to 2.3/10 postoperatively (p < 0.001). There was no statistically significant change in wrist range of motion (ROM), however. Arthroscopic debridement of the central perforation (1A lesion) with concomitant repair of the ulnar detachment (1B lesion) resulted in functional and symptomatic improvement. This combined 1A/1B TFC injury is not reliably diagnosed preoperatively and should be considered a new subset in the Palmer classification, as this will raise awareness of its presence and assist in preoperative planning of such lesions.

  12. Contamination of supplements: an interview with professor Ron Maughan by Louise M. Burke.

    PubMed

    Maughan, Ron

    2004-08-01

    This issue of IJSNEM features two articles related to supplement use by athletes. In one (Morrison et al. 2004), people who undertake regular exercise in a gym were found to report the use of a wide variety of supplements. The other paper (Goel et al. 2004) dealt with one of the issues that a sub-group of athletes need to consider before deciding to take supplements - the risk of a positive drug test if the product contains substances banned by the anti-doping codes under which their sport is conducted. This issue received much publicity earlier in the year when top tennis player Greg Rusedski tested positive for the steroid nandrolone as the result of inadvertent intake via a contaminated supplement. In this article, Professor Ron Maughan, Chair of Sports Nutrition at Loughborough University in the United Kingdom, advisor to the British Olympic team, and co-editor of IJSNEM, provides his insight on this important topic.

  13. Conjugate LEP Events at Palmer Station, Antarctica: Hemisphere-Dependent Timing

    NASA Astrophysics Data System (ADS)

    Kim, D.; Moore, R. C.

    2016-12-01

    During March 2015, a large number of lightning-induced electron precipitation (LEP) events were simultaneously observed using very low frequency receivers in both the northern and southern hemispheres. After removing overlapping events and unclear (or not well-defined) events, 22 conjugate LEP events remain and are used to statistically analyze the hemispheric dependence of LEP onset time. LEP events were detected in the northern hemisphere using the VLF remote sensing method by tracking the NAA transmitter signal (24.0 kHz, Cutler, Maine) at Tuscaloosa, Alabama. In the southern hemisphere, the NPM transmitter signal (21.4 kHz, Laulaulei, Hawii) is tracked at Palmer station, Antarctica. In each case, the GLD360 dataset from Vaisala is used to determine the hemisphere of the causative lightning flash, and this is compared with the hemisphere in which the LEP event is detected first. The onset times and onset durations can be calculated using a number of different methods, however. In this paper, we compare and contrast the onset times and durations calculated using multiple different methods, with each method applied to the same 22 conjugate LEP events.

  14. Asteroid Lightcurve Analysis at the Palmer Divide Observatory: 2012 September - 2013 January

    NASA Astrophysics Data System (ADS)

    Warner, Brian D.

    2013-04-01

    Lightcurves for 40 asteroids were obtained at the Palmer Divide Observatory (PDO) from 2012 September to 2013 January: 495 Eulalia, 1694 Kaiser, 2001 Einstein, 3086 Kalbaugh, 3635 Kreutz, 5806 Archieroy, 6310 Jankonke, 6447 Terrycole, 6744 Komoda, 7086 Bopp, 7560 Spudis, 8325 Trigo-Rodriguez, 11149 Tateshina, 11709 Eudoxos, (13245) 1998 MM19, (13573) 1993 FZ18, 14395 Tommorgan, 15434 Mittal, (17657) 1996 VO4, (22013) 1999 XO89, (26916) 1996 RR2, 27776 Cortland, (30878) 1992 GQ, (30981) 1995 SJ4, (31831) 1999 YL, (32626) 2001 RX64, (51371) 2000 XF15, 55844 Bicak, (55854) 1996 VS1, (63440) 2001 MD30, (66832) 1999 UE45, (70927) 1999 VX210, (72675) 2001 FP54, (86388) 2000 AT60, (90988) 1997 XS13, (123937) 2001 EX16, (136017) 2002 VH74, (192683) 1999 SO27, (330825) 2008 XE3, and 2012 TC4. Based on data and analysis in 2012 for 27776 Cortland, the previously reported period from 2009 has been revised.

  15. Comparing the Palmer Drought Index and the Standardized Precipitation Index for Zagreb-Gric Observatory

    NASA Astrophysics Data System (ADS)

    Pandzic, Kreso

    2016-04-01

    Conventional Palmer Drought Index (PDSI) and recent Standardized Precipitation Index (SPI) are compared for Zagreb-Gric weather station. Historical time series of PDSI and SPI are compared. For that purpose monthly precipitation, air temperature and air humidity data for Zagreb-Gric Observatory and period 1862-2012 are used. The results indicate that SPI is simpler for interpretation than PDSI. On the other side, lack of temperature within SPI, make impossible use of it on climate change applications. A comparison of PDSI and SPI for the periods from 1 to 24 months indicate the best agreement between PDSI and SPI for the periods from 6 to 12 months. In addition, correlation coefficients of determination between annual corn crop per hectare and SPI 9- months time scale and PDSI from May to October are shown as significant.

  16. Comparing the Palmer Drought Index and the Standardized Precipitation Index for Zagreb-Gric Observatory

    NASA Astrophysics Data System (ADS)

    Pandzic, Kreso

    2014-05-01

    Conventional Palmer Drought Index (PDSI) and recent Standardized Precipitation Index (SPI) are compared for Zagreb-Gric weather station. Historical time series of PDSI and SPI are compared. For that purpose monthly precipitation, air temperature and air humidity data for Zagreb-Gric Observatory and period 1862-2010 are used. The results indicate that SPI is simpler for interpretation than PDI. On the other side, lack of temperature within SPI, make impossible use of it on climate change applications. Further development of both indices is required. Possible applications of them in irrigation scheduling system is considered as well for drought risk assessment. In addition, a comparison of PDSI and SPI for the periods from 1 to 24 months indicate the best agreement between PDSI and SPI for the periods from 6 to 12 months.

  17. Spectacular reproduction: Ron's Angels and mechanical reproduction in the age of ART (assisted reproductive technology).

    PubMed

    Hafstein, Valdimar Tr

    2007-03-01

    Ron Harris captured the popular imagination in October 1999 with a website where he auctioned off the ova of fashion models to the highest bidder. This article treats the controversy surrounding Harris' site within a dual frame of critical theory's approach to reproduction and a folkloristic approach to discourse. The website fuses traditional narrative motifs and structures with the logic of advertising, seventies television, family-values rhetoric, and the fertility industry. I argue that the great attraction of ronsangels.com is that it put into relief the intervention of mechanical reproduction in human fertility together with the state of genetics at the turn of the 21st century. The result is not only a disconcerting aestheticization and commodification of biological reproduction, but also the biological reproduction of a particular aesthetic and moral code--a generation of reality by model.

  18. New insight into the thermal-tectonic history of the southern Antarctic Peninsula: (Uranium-Thorium-Samarium)/Helium and fission-track thermochronologic results from northwest Palmer Land and Alexander Island

    NASA Astrophysics Data System (ADS)

    Savrda, Amanda Marie

    2011-12-01

    This study examines the thermal history of the southern Antarctic Peninsula through the application of thermochronometry, and presents the first high-resolution thermochronologic dataset for arc rocks of northwest Palmer Land. I present 19 new thermochronologic ages obtained via (U-Th-Sm)/He and fission-track analyses of apatite and zircon from arc granitoids of northwest Palmer Land and fore-arc rocks of the LeMay and Fossil Bluff Groups of Alexander Island. These data were modeled via Monte Carlo simulations to generate time-temperature pathways. Thermal models generated for arc granitoids of northwest Palmer Land reveal a Late Cretaceous-Early Cenozoic episode of accelerated cooling from ca. 78--55 Ma not previously recognized in the southern Antarctic Peninsula. Here, faster cooling at an average rate of ˜15°C/Myr is bracketed by slower cooling at rates <3°C/Myr. Modeled thermal histories of metamorphosed fore-arc sedimentary rocks of Alexander Island reveal rapid cooling throughout the Eocene at an average rate of ˜13°C/Myr, preceded and followed by slower rates of cooling on the order of <3°C/Myr. The spatial and temporal distribution of the observed cooling trends may reflect localized variations in the thermal regime due to regional changes in plate kinematics, subduction dynamics, and related magmatism, but the cooling rates are also within range of those typical of exhumational processes such as normal faulting, ductile thinning, and erosion.

  19. "The expectation gap": a look at the Sybil Palmer Bellos lecture by Ruth B. Freeman, 1970.

    PubMed

    Abrams, Sarah E

    2005-01-01

    Ruth B. Freeman was an outstanding public health nurse leader of her time. Born in 1906, Freeman earned a doctorate and became an educator at Johns Hopkins University School of Hygiene and Public Health and a prolific author in the field of public health nursing. She spoke elegantly and forthrightly about the issues of public health, placing nursing on a par with other professions working toward the improvement of health on a global level. A year before her retirement, she was invited to give the Sybil Palmer Bellos lecture, an annual event that continues today at the Yale University School of Nursing. Selected excerpts from this lecture are reprinted in this analysis of Freeman's address. The entirety of the address was printed in Public Health Nursing, Volume 1, Issue 1, in 1984.

  20. Comparing photosynthetic characteristics of Isoetes sinensis Palmer under submerged and terrestrial conditions.

    PubMed

    Yang, Tao; Liu, Xing

    2015-12-04

    Crassulacean acid metabolism (CAM) is widespread in terrestrial and aquatic species, plastic in response to environmental changes. Isoetes L. is one of the earliest basal vascular plants and CAM is popular in this genus. Isoetes sinensis Palmer is an amphibious species, alternating frequently between terrestrial and aquatic environments. Given this, we investigated and compared photosynthetic characteristics over a diurnal cycle under submerged condition (SC) and terrestrial condition (TC). The results suggest that I. sinensis possesses a stronger CAM capacity under SC. Compared with under TC, titratable acidity levels and organic acid concentrations were more enriched under SC, whereas soluble sugar or starch and protein levels were lower under SC. Transcript analyses for nine photosynthetic genes revealed that CAM-associated genes possessed high transcripts under SC, but C3-related transcripts were highly expressed under TC. In addition, the enzyme activity measurements demonstrated that PEPC activity over a diurnal cycle was slightly higher under SC, whereas Rubisco activity during the daytime was greater under TC. This comprehensive study probably facilitates general understandings about the CAM photosynthetic characteristics of Isoetes in response to the environmental changes.

  1. Variable tolerance among Palmer amaranth (Amaranthus palmeri) biotypes to glyphosate, 2,4-D amine, and premix formulation of glyphosate plus 2,4-D choline (Enlist Duo®) herbicide

    USDA-ARS?s Scientific Manuscript database

    Adoption of soybean that is resistant to 2,4-D will result in more use of glyphosate plus 2,4-D premixes and tank-mixtures. Preliminary whole-plant greenhouse assays confirm most Palmer amaranth found in Indiana are glyphosate-resistant (GR) and some biotypes exhibit tolerance to 2,4-D amine. Dose r...

  2. Resistance to PPO‐inhibiting herbicide in Palmer amaranth from Arkansas

    PubMed Central

    Salas, Reiofeli A; Tranel, Patrick J; Singh, Shilpa; Glasgow, Les; Scott, Robert C; Nichols, Robert L

    2016-01-01

    Abstract BACKGROUND The widespread occurrence of ALS inhibitor‐ and glyphosate‐resistant Amaranthus palmeri has led to increasing use of protoporphyrinogen oxidase (PPO)‐inhibiting herbicides in cotton and soybean. Studies were conducted to confirm resistance to fomesafen (a PPO inhibitor), determine the resistance frequency, examine the resistance profile to other foliar‐applied herbicides and investigate the resistance mechanism of resistant plants in a population collected in 2011 (AR11‐LAW B) and its progenies from two cycles of fomesafen selection (C1 and C2). RESULTS The frequency of fomesafen‐resistant plants increased from 5% in the original AR11‐LAW‐B to 17% in the C2 population. The amounts of fomesafen that caused 50% growth reduction were 6‐, 13‐ and 21‐fold greater in AR11‐LAW‐B, C1 and C2 populations, respectively, than in the sensitive ecotype. The AR11‐LAW‐B population was sensitive to atrazine, dicamba, glufosinate, glyphosate and mesotrione but resistant to ALS‐inhibiting herbicides pyrithiobac and trifloxysulfuron. Fomesafen survivors from C1 and C2 populations tested positive for the PPO glycine 210 deletion previously reported in waterhemp (Amaranthus tuberculatus). CONCLUSION These studies confirmed that Palmer amaranth in Arkansas has evolved resistance to foliar‐applied PPO‐inhibiting herbicide. © 2016 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry. PMID:26817647

  3. Cold atmospheric plasma (CAP), a novel physicochemical source, induces neural differentiation through cross-talk between the specific RONS cascade and Trk/Ras/ERK signaling pathway.

    PubMed

    Jang, Ja-Young; Hong, Young June; Lim, Junsup; Choi, Jin Sung; Choi, Eun Ha; Kang, Seongman; Rhim, Hyangshuk

    2018-02-01

    Plasma, formed by ionization of gas molecules or atoms, is the most abundant form of matter and consists of highly reactive physicochemical species. In the physics and chemistry fields, plasma has been extensively studied; however, the exact action mechanisms of plasma on biological systems, including cells and humans, are not well known. Recent evidence suggests that cold atmospheric plasma (CAP), which refers to plasma used in the biomedical field, may regulate diverse cellular processes, including neural differentiation. However, the mechanism by which these physicochemical signals, elicited by reactive oxygen and nitrogen species (RONS), are transmitted to biological system remains elusive. In this study, we elucidated the physicochemical and biological (PCB) connection between the CAP cascade and Trk/Ras/ERK signaling pathway, which resulted in neural differentiation. Excited atomic oxygen in the plasma phase led to the formation of RONS in the PCB network, which then interacted with reactive atoms in the extracellular liquid phase to form nitric oxide (NO). Production of large amounts of superoxide radical (O 2 - ) in the mitochondria of cells exposed to CAP demonstrated that extracellular NO induced the reversible inhibition of mitochondrial complex IV. We also demonstrated that cytosolic hydrogen peroxide, formed by O 2 - dismutation, act as an intracellular messenger to specifically activate the Trk/Ras/ERK signaling pathway. This study is the first to elucidate the mechanism linking physicochemical signals from the CAP cascade to the intracellular neural differentiation signaling pathway, providing physical, chemical and biological insights into the development of therapeutic techniques to treat neurological diseases. Copyright © 2017 Elsevier Ltd. All rights reserved.

  4. National Program for Inspection of Non-Federal Dams. Palmer Brook Dam MA 00205, Connecticut River Basin, Becket, Massachusetts. Phase I Inspection Report.

    DTIC Science & Technology

    1981-03-01

    DAMS PALMER BROOK DAM LOCATION MAP 2010 OpO 9 1Q00 20-0 AND DRAINAGE AREA DRAWN ICHECKED APPROVED SCALE AS SHOWN SCALE IN FEET L L R D B W F J. K. DATE...BROOK DAM EXHIBIT C-2-DIKE GUIDE TO PHOTOGRAPHS DRAWN iCHECKED JAPPOVED ,SCALE: 1.1K 5F0FT. L.L.R. D.B.W. F. J.K. JDATE: 2/8I PAGE C-2 ,it PRODUJCED A...ooo opo2000FLOOD IMPACT AREA P SALEIN EETDRAWN ICHECKED IAPPROVED ISCALE AS SHOWN SCALE__________IN______________ L. L. R. D. B. W. IF J. K. JDATE 2

  5. Appraising Loftus and Palmer (1974) post-event information versus concurrent commentary in the context of sport.

    PubMed

    Goldschmied, Nadav; Sheptock, Mark; Kim, Kacey; Galily, Yair

    2017-11-01

    Two experiments were conducted to examine framing effects in sport. In Experiment 1, a conceptual replication [Loftus, E. F., & Palmer, J. C. (1974). Reconstruction of automobile destruction: An example of the interaction between language and memory. Journal of Verbal Learning and Verbal Behavior, 13(5), 585-589], participants watched a hockey collision, with the hit described later in a written format as a "contact", "bump", or "smash". This manipulation resulted in no differences in participants' report of how fast the players were skating, their intentions, and the outcome of the hit. In Experiment 2, participants watched the same video clip with ongoing commentary. Those who heard the announcer describing the event as "contact" estimated a higher skating speed than participants who were exposed to the "smash" commentary. Participants who were exposed to the "bump" commentary rated the repercussions of the collision as less severe than did those exposed to the other commentaries. These findings show that the perception of magnitude hierarchy may be domain specific and suggest future avenues for exploring framing effects when one is exposed to visual stimuli.

  6. Management of patients under general anesthesia with mafutsu-san in Hanaoka-style surgery: comparisons of illustrations from Geka-Kihai-Zufu with descriptions from Mafutsuto-Ron and Yohka-Hiroku.

    PubMed

    Dote, Kentaro; Yorozuya, Tosihiro; Ikemune, Keizo; Desaki, Yoko

    2015-02-01

    Seishu Hanaoka (1760-1835) left behind no books that he himself had written. This is why many aspects of Hanaoka-style general anesthesia using a mixture of herbal extracts, which he called mafutsu-san, remain unknown. We are able to learn about this technique today because there are several descriptions of it in books written by his students, such as Mafutsuto-Ron ("Treatise on Mafutsuto") by Gendai Kamata (1794-1854) and Yohka-Hiroku ("Secret Records of Surgery") by Gencho Homma (1804-1872). On the other hand, Geka-Kihai-Zufu ("Illustrations of Surgical Cases"), a surgical textbook, by Gendai Kamata, containing one of the oldest illustrations of general anesthesia published in 1840, was recently rediscovered (2011). For the first time, this book revealed, in the form of a picture image, the actual circumstances of Hanaoka-style general anesthesia. We therefore compared the descriptions of general anesthesia featured in these three documents, and thereby investigated the actual anesthetic management and the procedures used. We found that the circumstances under which Hanaoka-style general anesthesia, using fabrics and futon mattresses, as well as blindfolding and constraining the patient's body during surgery, were exactly as described in Mafutsuto-Ron and Yohka-Hiroku. In addition, besides a surgeon conducting an operation, there was a physician who observed the patient's general condition. Gendai Kamata, the author of Geka-Kihai-Zufu, is believed to have recognized the importance of anesthetic care of surgical patients.

  7. Environmental arsenic exposure and risk of diabetes type 2 in Ron Phibun subdistrict, Nakhon Si Thammarat Province, Thailand: unmatched and matched case–control studies

    PubMed Central

    Sripaoraya, Kwanyuen; Siriwong, Wattasit; Pavittranon, Sumol; Chapman, Robert S

    2017-01-01

    Background There are inconsistent findings on associations between low-to-moderate level of arsenic in water and diabetes risk from previous epidemiological reports. In Ron Phibun subdistrict, Nakhon Si Thammarat Province, Thailand, a low level of arsenic exposure among population was observed and increased diabetes mellitus (DM) rate was identified. Objectives We aimed to investigate the association between determinants (including low-level water arsenic exposure) of DM type 2 risk among residents of three villages of Ron Phibun subdistrict, Nakhon Si Thammarat Province. Materials and methods Secondary data from two previous community based-studies, conducted in 2000 and 2008, were utilized. Data on independent variables relating to arsenic exposure and sociodemographic characteristics were taken from questionnaires and worksheets for health-risk screening. Water samples collected during household visit were sent for analysis of arsenic level at certified laboratories. Diabetes cases (N=185) were those who had been diagnosed with DM type 2. Two groups of controls, one unmatched to cases (n=200) and one pair matched on age and gender (n=200), were selected for analysis as unmatched and matched case–control studies, respectively. A multiple imputation technique was used to impute missing values of independent variables. Multivariable logistic regression models, with independent variables for arsenic exposure and sociodemographic characteristics, were constructed. The unmatched and matched data sets were analyzed using unconditional and conditional logistic analyses, respectively. Results Older age, body mass index (BMI), having a history of illness in siblings and parents, and drinking were associated with increased DM type 2 risk. We found no convincing association between DM type 2 risk and water arsenic concentration in either study. Conclusion We did not observe meaningful association between diabetes risk and the low-to-moderate arsenic levels observed in

  8. R-on-1 automatic mapping: A new tool for laser damage testing

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hue, J.; Garrec, P.; Dijon, J.

    1996-12-31

    Laser damage threshold measurement is statistical in nature. For a commercial qualification or for a user, the threshold determined by the weakest point is a satisfactory characterization. When a new coating is designed, threshold mapping is very useful. It enables the technology to be improved and followed more accurately. Different statistical parameters such as the minimum, maximum, average, and standard deviation of the damage threshold as well as spatial parameters such as the threshold uniformity of the coating can be determined. Therefore, in order to achieve a mapping, all the tested sites should give data. This is the major interestmore » of the R-on-1 test in spite of the fact that the laser damage threshold obtained by this method may be different from the 1-on-1 test (smaller or greater). Moreover, on the damage laser test facility, the beam size is smaller (diameters of a few hundred micrometers) than the characteristic sizes of the components in use (diameters of several centimeters up to one meter). Hence, a laser damage threshold mapping appears very interesting, especially for applications linked to large optical components like the Megajoule project or the National Ignition Facility (N.I.F). On the test bench used, damage detection with a Nomarski microscope and scattered light measurement are almost equivalent. Therefore, it becomes possible to automatically detect on line the first defects induced by YAG irradiation. Scattered light mappings and laser damage threshold mappings can therefore be achieved using a X-Y automatic stage (where the test sample is located). The major difficulties due to the automatic capabilities are shown. These characterizations are illustrated at 355 nm. The numerous experiments performed show different kinds of scattering curves, which are discussed in relation with the damage mechanisms.« less

  9. Joint spatiotemporal variability of global sea surface temperatures and global Palmer drought severity index values

    USGS Publications Warehouse

    Apipattanavis, S.; McCabe, G.J.; Rajagopalan, B.; Gangopadhyay, S.

    2009-01-01

    Dominant modes of individual and joint variability in global sea surface temperatures (SST) and global Palmer drought severity index (PDSI) values for the twentieth century are identified through a multivariate frequency domain singular value decomposition. This analysis indicates that a secular trend and variability related to the El Niño–Southern Oscillation (ENSO) are the dominant modes of variance shared among the global datasets. For the SST data the secular trend corresponds to a positive trend in Indian Ocean and South Atlantic SSTs, and a negative trend in North Pacific and North Atlantic SSTs. The ENSO reconstruction shows a strong signal in the tropical Pacific, North Pacific, and Indian Ocean regions. For the PDSI data, the secular trend reconstruction shows high amplitudes over central Africa including the Sahel, whereas the regions with strong ENSO amplitudes in PDSI are the southwestern and northwestern United States, South Africa, northeastern Brazil, central Africa, the Indian subcontinent, and Australia. An additional significant frequency, multidecadal variability, is identified for the Northern Hemisphere. This multidecadal frequency appears to be related to the Atlantic multidecadal oscillation (AMO). The multidecadal frequency is statistically significant in the Northern Hemisphere SST data, but is statistically nonsignificant in the PDSI data.

  10. Tidal inlet response to sediment infilling of the associated bay and possible implications of human activities: the Marennes-Oléron Bay and the Maumusson Inlet, France

    NASA Astrophysics Data System (ADS)

    Bertin, Xavier; Chaumillon, Eric; Sottolichio, Aldo; Pedreros, Rodrigo

    2005-06-01

    Tidal inlet characteristics are controlled by wave energy, tidal range, tidal prism, sediment supply and direction and rates of sand delivered to the inlet. This paper deals with the relations between inlet and lagoon evolutions, linked by the tidal prism. Our study is focused on the Maumusson Inlet and the Marennes-Oléron Bay (first oyster farming area in Europe), located on the western coast of France. The tidal range (2-6 m) and wave climate (mean height: 1.5 m) place this tidal inlet system in the mixed energy (tide, waves), tide-dominated category. The availability of high-resolution bathymetric data since 1824 permits to characterise and quantify accurately morphological changes of both the inlet and the tidal bay. Since 1824, sediment filling of the tidal bay has led to a 20% decrease in its water volume, and a 35% reduction of the inlet throat section. Furthermore, the bay is subjected to a very high anthropic pressure, mainly related to oyster farming. Thus, both natural and human-related processes seem relevant to explain high sedimentation rates. Current measurements, hydrodynamic modelling and cross-sectional area of the inlet throat are used in order to quantify tidal prism changes since 1824. Both flood and ebb tidal prism decreased by 35%. Decrease in the Marennes-Oléron Bay water volume is inferred to be responsible for a part of tidal prism decrease at the inlet. Tidal prisms decrease may also be explained by an increase in frictional resistance to tidal wave propagation, due to a general shoaling and oyster farms in the bay. A conceptual model is proposed, taking into account natural and human-related sedimentation processes, and explaining tidal inlet response to tidal bay evolutions.

  11. ELF Transients and Q-bursts Detected Around the Globe: First results from Palmer Station, Antarctica

    NASA Astrophysics Data System (ADS)

    Flint, Q. A.; Moore, R. C.

    2016-12-01

    We present the first analysis of data from the recently deployed broadband ELF (5-500 Hz) B-field receiver at Palmer Station, Antarctica together with observations at similar receivers located at Sondrestromfjord, Greenland and Arrival Heights, Antarctica. Such remote locations afford the unique opportunity to record signals that are essentially unperturbed by power line noise. As a result, using this multi-site global network of ELF/VLF receivers, we are able to easily detect a particular type of ELF transient that propagates around the world multiple times, known as the Q-burst. The Q-burst is characterized by a large increase in amplitude above the background at the Schumann Resonance modes and is believed to result from especially powerful cloud-to-ground lightning discharges. These powerful lightning discharges are likely responsible for a significant level of energetic coupling between the troposphere, the ionosphere, and the magnetosphere. The ELF and VLF waves excited by the lightning discharge propagate to great distances in the earth-ionosphere waveguide, and in fact propagate around the Earth multiple times. By measuring the received waveform at multiple distant sites around the globe, we can pinpoint the source lightning location, compare the changes in field strength and spectrum as a function of distance from the source, and evaluate modal propagation effects in the VLF range (that are not apparent in the ELF range).

  12. Classification of ulnar triangular fibrocartilage complex tears. A treatment algorithm for Palmer type IB tears.

    PubMed

    Atzei, A; Luchetti, R; Garagnani, L

    2017-05-01

    The classical definition of 'Palmer Type IB' triangular fibrocartilage complex tear, includes a spectrum of clinical conditions. This review highlights the clinical and arthroscopic criteria that enable us to categorize five classes on a treatment-oriented classification system of triangular fibrocartilage complex peripheral tears. Class 1 lesions represent isolated tears of the distal triangular fibrocartilage complex without distal radio-ulnar joint instability and are amenable to arthroscopic suture. Class 2 tears include rupture of both the distal triangular fibrocartilage complex and proximal attachments of the triangular fibrocartilage complex to the fovea. Class 3 tears constitute isolated ruptures of the proximal attachment of the triangular fibrocartilage complex to the fovea; they are not visible at radio-carpal arthroscopy. Both Class 2 and Class 3 tears are diagnosed with a positive hook test and are typically associated with distal radio-ulnar joint instability. If required, treatment is through reattachment of the distal radio-ulnar ligament insertions to the fovea. Class 4 lesions are irreparable tears due to the size of the defect or to poor tissue quality and, if required, treatment is through distal radio-ulnar ligament reconstruction with tendon graft. Class 5 tears are associated with distal radio-ulnar joint arthritis and can only be treated with salvage procedures. This subdivision of type IB triangular fibrocartilage complex tear provides more insights in the pathomechanics and treatment strategies. II.

  13. Asteroid Lightcurve Analysis at the Palmer Divide Observatory: 2011 December - 2012 March

    NASA Astrophysics Data System (ADS)

    Warner, Brian D.

    2012-07-01

    Lightcurves for 41 asteroids were obtained at the Palmer Divide Observatory (PDO) from 2011 December to 2012 March: 77 Frigga, 2933 Amber, 3352 McAuliffe, 3483 Svetlov, 4031 Mueller, 5378 Ellyett, 5579 Uhlherr, 5771 Somerville, 6087 Lupo, 6602 Gilclark, (6618) 1936 SO, 6635 Zuber, (8404) 1995 AN, (9873) 1992 GH, (11058) 1991 PN10, (16421) 1988 BJ, (16426) 1988 EC, (16585) 1992 QR, 16589 Hastrup, 18368 Flandrau, (19537) 1999 JL8, (23974) 1999 CK12, (24465) 2000 SX155, (26383) 1999 MA2, (30856) 1991 XE, (39618) 1994 LT, (45898) 2000 XQ49, (47983) 2000 XX13, (49566) 1999 CM106, (49678) 1999 TQ7, (50991) 2000 GK94, (57739) 2001 UF162, (63260) 2001 CN, (69350) 1993 YP, 79316 Huangshan, (82066) 2000 XG15, (82078) 2001 AH46, (105155) 2000 NG26, (141018) 2001 WC47, (256700) 2008 AG3, (320125) 2007 EQ185. Two asteroids showed indications of being binary. Analysis of the data for near-Earth asteroid, 3352 McAuliffe showed a second period of 20.86 h but no obvious mutual events (occultations and/or eclipses). The Hungaria asteroid, (24465) 2000 SX15, displayed similar characteristics. Furthermore, the primary (or only) period of 3.256 h cannot be reconciled with analysis from previous apparitions. Three asteroids showed signs of being in non-principal axis rotation (NPAR, "tumbling"). New values for absolute magnitude (H) were found for several Hungaria asteroids using either derived or assumed values of G. These new values were compared against those used in the WISE mission to determine diameters and albedos. In all cases where the WISE results featured an unusually high albedo for the asteroid in question, the new value of H resulted in an albedo that was significantly lower and closer to the expected value for type E asteroids, which are the likely members of the Hungaria collisional family.

  14. Positive and normative modeling for Palmer amaranth control and herbicide resistance management.

    PubMed

    Frisvold, George B; Bagavathiannan, Muthukumar V; Norsworthy, Jason K

    2017-06-01

    Dynamic optimization models are normative; they solve for what growers 'ought to do' to maximize some objective, such as long-run profits. While valuable for research, such models are difficult to solve computationally, limiting their applicability to grower resistance management education. While discussing properties of normative models in general, this study presents results of a specific positive model of herbicide resistance management, applied to Palmer amaranth control on a representative cotton farm. This positive model compares a proactive resistance management strategy to a reactive strategy with lower short-run costs, but greater risk of herbicide resistance developing. The proactive strategy can pay for itself within 1-4 years, with a yield advantage of 4% or less if the yield advantage begins within 1-2 years of adoption. Whether the proactive strategy is preferable is sensitive to resistance onset and yield losses, but less sensitive to cotton prices or baseline yields. Industry rebates to encourage residual herbicide use (to delay resistance to post-emergence treatments) may be too small to alter grower behavior or they may be paid to growers who would have used residuals anyway. Rebates change grower behavior over a relatively narrow range of model parameters. The size of rebates needed to induce a grower to adopt the proactive strategy declines significantly if growers extend their planning horizon from 1 year to 3-4 years. Whether proactive resistance management is more profitable than a reactive strategy is more sensitive to biological parameters than economic ones. Simulation results suggest growers with longer time horizons (perhaps younger ones) would be more responsive to rebate programs. More empirical work is needed to determine how much rebates increase residual use above what would occur without them. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.

  15. An investigation of several aspects of LANDSAT-5 data quality. [Palmer County, Shelby, mt; White sands, NM; Great Salt Lake, UT; San Matted Bridge and Sacramento, California

    NASA Technical Reports Server (NTRS)

    Wrigley, R. C. (Principal Investigator)

    1984-01-01

    Band-to-band registration, geodetic registration, interdector noise, and the modulation transfer function (MTE) are discussed for the Palmer County; TX scene. Band combinations for several LANDSAT 4 and LANDSAT 5 scenes; the geodetic registration test for the Sacramento, CA area; periodic noise components in TM band 5; and grey level measurements by detector for Great Salt Lake (UT) dark water forescans and backscans are considered. Results of MTF analyses of the San Mateo Bridge and of TM high resolution and aerial Daedalus scanner imagery are consistent and appear to be repeatable. An oil-on-sand target was constructed on the White Sands Missile Range in New Mexico. The two-image analysis procedure used is summarized.

  16. Determination of Carbon Dioxide, Hydrograohic, and Chemical Parameters During the R/V Nathaniel B. Palmer Cruise in the Southern Indian Ocean (WOCE Section S04I, 3 May - 4 July, 1996)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kozyr, Alex

    This report discusses the procedures and methods used to measure total carbon dioxide (TCO 2), total alkalinity (TALK), and partial pressure of CO 2 (pCO 2) at hydrographic stations during the cruise of research vessel (R/V) Nathaniel B. Palmer in the Southern Indian Ocean on the S04I Section as a part of the Joint Global Ocean Flux Study (JGOFS)/World Ocean Circulation Experiment (WOCE). The carbon-related measurements were sponsored by the U.S. Department of Energy (DOE). The expedition started in Cape Town, South Africa, on May 3, 1996, and ended in Hobart, Australia, on July 4, 1996. Instructions for accessing themore » data are provided. The TCO 2 was measured in discrete water samples using the Lamont-Doherty Earth Observatory (LDEO) coulomteric system with an overall precision of ±1.7 μmol/kg. TALK was determined by potentiometric titration with an overall precision of ±1.7 μmol/kg. During the S04I cruise pCO 2 was also measured using the LDEO equilibrator-gas chromatograph system with a precision of 0.5% (including the station-to-station reproducibility) at a constant temperature of 4.0ºC. The R/V Nathaniel B. Palmer S04I data set is available free of charge as a numeric data package (NDP) from the Carbon Dioxide Information Analysis Center. The NDP consists of the oceanographic data files and this printed documentation, which describes the contents and format of all files as well as the procedures and methods used to obtain the data.« less

  17. Effects of short-term environmental disturbances on living benthic foraminifera during the Pacific oyster summer mortality in the Marennes-Oléron Bay (France).

    PubMed

    Bouchet, Vincent M P; Debenay, Jean-Pierre; Sauriau, Pierre-Guy; Radford-Knoery, Joël; Soletchnik, Patrick

    2007-09-01

    Sediment cores were collected from April to August 2004 on tidal mudflats of the macrotidal Marennes-Oléron Bay (SW France), famous for the cultivation of Pacific oysters (Crassostrea gigas). The response of living (stained) benthic foraminifera to short-term biogeochemical disturbances in the sediment and overlying water, which may be involved in oyster summer mortality, was monitored. Short-term hypoxia occurred in early June, in conjunction with a sudden rise in temperature. In mid-June, the ammonia content of sediment porewater increased, leading to potentially maximal flux towards overlying waters. Foraminiferal assemblages, particularly in the topmost layer, were altered. Ammonia tepida was the most tolerant to temperature increase and hypoxic conditions whereas Brizalina variabilis and Haynesina germanica were sensitive to organic degradation and hypoxia. Cribroelphidium gunteri was the most opportunistic during recolonisation. Benthic foraminifera showed that short-term biochemical changes in the sediment are toxic and may be involved in the summer mortality of Pacific oysters.

  18. Isotopic Determination of Food Sources of Crassostrea gigasAlong a Trophic Gradient in the Estuarine Bay of Marennes-Ol éron

    NASA Astrophysics Data System (ADS)

    Riera, P.; Richard, P.

    1996-03-01

    Along a trophic gradient from the head of an estuary to the open ocean, carbon isotope ratios were determined both in tissues of the Pacific oyster Crassostrea gigasand in different components of the oysters ' potential food resource. In the study area, the Marennes-Ol éron Bay (France), a gradient in δ 13C occurred in the particulate organic carbon (POC) from riverine ( -29 ·2 - -27 ·4 ‰) to open sea littoral ( -21 ·8 - -19 ·5 ‰). Isotope composition of oysters collected along this estuarine gradient followed a similar trend, indicating a predominant contribution of organic matter derived from terrestrial detritus to the diet of C. gigasinhabiting the upper estuarine reaches. A remarkable departure from this general pattern was noted in the isotope composition of oysters sampled from a reef, at the mouth of the Charente river. These oysters exhibited enriched 13C composition, suggesting that they were largely feeding upon benthic microalgae ( -16 ‰) from an adjacent wide mudflat. The reported results suggest that C. gigasis able to preferentially ingest and/or assimilate particular food sources (i.e. benthic diatoms) among diverse sources within the total organic matter pool.

  19. Phase Competition in the Palmer-Chalker X Y Pyrochlore Er2Pt2O7

    NASA Astrophysics Data System (ADS)

    Hallas, A. M.; Gaudet, J.; Butch, N. P.; Xu, Guangyong; Tachibana, M.; Wiebe, C. R.; Luke, G. M.; Gaulin, B. D.

    2017-11-01

    We report neutron scattering measurements on Er2Pt2O7 , a new addition to the X Y family of frustrated pyrochlore magnets. Symmetry analysis of our elastic scattering data shows that Er2Pt2O7 orders into the k =0 , Γ7 magnetic structure (the Palmer-Chalker state), at TN=0.38 K . This contrasts with its sister X Y pyrochlore antiferromagnets Er2Ti2O7 and Er2Ge2O7 , both of which order into Γ5 magnetic structures at much higher temperatures, TN=1.2 and 1.4 K, respectively. In this temperature range, the magnetic heat capacity of Er2Pt2O7 contains a broad anomaly centered at T*=1.5 K . Our inelastic neutron scattering measurements reveal that this broad heat capacity anomaly sets the temperature scale for strong short-range spin fluctuations. Below TN=0.38 K , Er2Pt2O7 displays a gapped spin-wave spectrum with an intense, flat band of excitations at lower energy and a weak, diffusive band of excitations at higher energy. The flat band is well described by classical spin-wave calculations, but these calculations also predict sharp dispersive branches at higher energy, a striking discrepancy with the experimental data. This, in concert with the strong suppression of TN, is attributable to enhanced quantum fluctuations due to phase competition between the Γ7 and Γ5 states that border each other within a classically predicted phase diagram.

  20. Hemophilia Treatments Have Come a Long Way

    MedlinePlus

    ... Nisha Jain, M.D., chief of the Clinical Review Branch in FDA’s Office of Blood Research and Review. Hemophilia A occurs when people have low levels, ... Nisha Jain, M.D., chief of the Clinical Review Branch in FDA’s Office of Blood Research and ...

  1. Investigating the Mobility of Light Autonomous Tracked Vehicles using a High Performance Computing Simulation Capability

    DTIC Science & Technology

    2012-08-01

    Madison, WI 53706 David Lamb Paramsothy Jayakumar Michael Letherwood U.S. Army TARDEC Warren, MI 48397 Abhinandan Jain Marco Quadrelli Jet Propulsion...PROGRAM ELEMENT NUMBER 6. AUTHOR(S) David Lamb; Paramsothy Jayakumar ; Mike Letherwood; Dan Negrut; Abhinandan Jain 5d. PROJECT NUMBER 5e. TASK

  2. Delineating depth to bedrock beneath shallow unconfined aquifers: a gravity transect across the Palmer River Basin.

    PubMed

    Bohidar, R N; Sullivan, J P; Hermance, J F

    2001-01-01

    In view of the increasing demand on ground water supplies in the northeastern United States, it is imperative to develop appropriate methods to geophysically characterize the most widely used sources of ground water in the region: shallow unconfined aquifers consisting of well-sorted, stratified glacial deposits laid down in bedrock valleys and channels. The gravity method, despite its proven value in delineating buried bedrock valleys elsewhere, is seldom used by geophysical contractors in this region. To demonstrate the method's effectiveness for evaluating such aquifers, a pilot study was undertaken in the Palmer River Basin in southeastern Massachusetts. Because bedrock is so shallow beneath this aquifer (maximum depth is 30 m), the depth-integrated mass deficiency of the overlying unconsolidated material was small, so that the observed gravity anomaly was on the order of 1 milligal (mGal) or less. Thus data uncertainties were significant. Moreover, unlike previous gravity studies elsewhere, we had no a priori information on the density of the sediment. Under such circumstances, it is essential to include model constraints and weighted least-squares in the inversion procedure. Among the model constraints were water table configuration, bedrock outcrops, and depth to bedrock from five water wells. Our procedure allowed us to delineate depth to bedrock along a 3.5 km profile with a confidence interval of 1.8 m at a nominal depth of 17 m. Moreover, we obtained a porosity estimate in the range of 39% to 44%. Thus the gravity method, with appropriate refinements, is an effective tool for the reconnaissance of shallow unconfined aquifers.

  3. Hypobaric Hypoxia (380 Torr) Decreases Intracellular and Total Body Water in Goats

    DTIC Science & Technology

    1989-01-01

    109-111, 1989. 16. Jain, S.C., J. Bardhan , Y.V. Swamy, B. Krishna, and H.S. Nayar. Body fluid compartments in humans during acute high- altitude...exposure. Aviat. Space Environ. Med. 51:234-236, 1980. 17. Jain, S.C., J. Bardhan , Y.V. Swamy, A. Grover, and H.S. Nayar. Body water metabolism in high

  4. AMPK signaling in skeletal muscle during exercise: Role of reactive oxygen and nitrogen species.

    PubMed

    Morales-Alamo, David; Calbet, Jose A L

    2016-09-01

    Reactive oxygen and nitrogen species (RONS) are generated during exercise depending on intensity, duration and training status. A greater amount of RONS is released during repeated high-intensity sprint exercise and when the exercise is performed in hypoxia. By activating adenosine monophosphate-activated kinase (AMPK), RONS play a critical role in the regulation of muscle metabolism but also in the adaptive responses to exercise training. RONS may activate AMPK by direct an indirect mechanisms. Directly, RONS may activate or deactivate AMPK by modifying RONS-sensitive residues of the AMPK-α subunit. Indirectly, RONS may activate AMPK by reducing mitochondrial ATP synthesis, leading to an increased AMP:ATP ratio and subsequent Thr(172)-AMPK phosphorylation by the two main AMPK kinases: LKB1 and CaMKKβ. In presence of RONS the rate of Thr(172)-AMPK dephosphorylation is reduced. RONS may activate LKB1 through Sestrin2 and SIRT1 (NAD(+)/NADH.H(+)-dependent deacetylase). RONS may also activate CaMKKβ by direct modification of RONS sensitive motifs and, indirectly, by activating the ryanodine receptor (Ryr) to release Ca(2+). Both too high (hypoxia) and too low (ingestion of antioxidants) RONS levels may lead to Ser(485)-AMPKα1/Ser(491)-AMPKα2 phosphorylation causing inhibition of Thr(172)-AMPKα phosphorylation. Exercise training increases muscle antioxidant capacity. When the same high-intensity training is applied to arm and leg muscles, arm muscles show signs of increased oxidative stress and reduced mitochondrial biogenesis, which may be explained by differences in RONS-sensing mechanisms and basal antioxidant capacities between arm and leg muscles. Efficient adaptation to exercise training requires optimal exposure to pulses of RONS. Inappropriate training stimulus may lead to excessive RONS formation, oxidative inactivation of AMPK and reduced adaptation or even maladaptation. Theoretically, exercise programs should be designed taking into account the

  5. Climate forcing for dynamics of dissolved inorganic nutrients at Palmer Station, Antarctica: An interdecadal (1993-2013) analysis

    NASA Astrophysics Data System (ADS)

    Kim, Hyewon; Doney, Scott C.; Iannuzzi, Richard A.; Meredith, Michael P.; Martinson, Douglas G.; Ducklow, Hugh W.

    2016-09-01

    We analyzed 20 years (1993-2013) of observations of dissolved inorganic macronutrients (nitrate, N; phosphate, P; and silicate, Si) and chlorophyll a (Chl) at Palmer Station, Antarctica (64.8°S, 64.1°W) to elucidate how large-scale climate and local physical forcing affect the interannual variability in the seasonal phytoplankton bloom and associated drawdown of nutrients. The leading modes of nutrients (N, P, and Si empirical orthogonal functions 1, EOF1) represent overall negative anomalies throughout growing seasons, showing a mixed signal of variability in the initial levels and drawdown thereafter (low-frequency dynamics). The second most common seasonal patterns of nitrate and phosphate (N and P EOF2) capture prolonged drawdown events during December-March, which are correlated to Chl EOF1. Si EOF2 captures a drawdown event during November-December, which is correlated to Chl EOF2. These different drawdown patterns are shaped by different sets of physical and climate forcing mechanisms. N and P drawdown events during December-March are influenced by the winter and spring Southern Annular Mode (SAM) phase, where nutrient utilization is enhanced in a stabilized upper water column as a consequence of SAM-driven winter sea ice and spring wind dynamics. Si drawdown during November-December is influenced by early sea ice retreat, where ice breakup may induce abrupt water column stratification and a subsequent diatom bloom or release of diatom cells from within the sea ice. Our findings underscore that seasonal nutrient dynamics in the coastal WAP are coupled to large-scale climate forcing and related physics, understanding of which may enable improved projections of biogeochemical responses to climate change.

  6. Fuel Composition Effects at Constant RON and MON in an HCCI Engine Operated with Negative Valve Overlap

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bunting, Bruce G; Farrell, John T

    2006-01-01

    The effects of fuel properties on gasoline HCCI operation have been investigated in a single cylinder, 500 cc, 11.3 CR port fuel injected research engine, operated at lambda=1 and equipped with hydraulic valve actuation. HCCI is promoted by early exhaust valve closing to retain hot exhaust in the cylinder, thereby increasing the cylinder gas temperature. Test fuels were formulated with pure components to have the same RON, MON, and octane sensitivity as an indolene reference fuel, but with a wide range of fuel composition differences. Experiments have been carried out to determine if fuel composition plays a role in HCCImore » combustion properties, independent of octane numbers. Fuel economy, emissions, and combustion parameters have been measured at several fixed speed/load conditions over a range of exhaust valve closing angles. When the data are compared at constant combustion phasing, fuel effects on emissions and other combustion properties are small. However, when compared at constant exhaust valve closing angle, fuel composition effects are more pronounced, specifically regarding ignition. Operability range differences are also related to fuel composition. An all-paraffinic (normal, iso, and cycloparaffins) fuel exhibited distinctly earlier combustion phasing, increased rate of cylinder pressure rise, and increased rate of maximum heat release compared to the indolene reference fuel. Conversely, olefin-containing fuels exhibited retarded combustion phasing. The fuels with the most advanced ignition showed a wider operating range in terms of engine speed and load, irrespective of exhaust closing angle. These ignition differences reflect contributions from both fuel and EGR kinetics, the effects of which are discussed. The fuel composition variables are somewhat inter-correlated, which makes the experimental separation their effects imprecise with this small set of fuels, though clear trends are evident. The overall effects of fuel composition on engine

  7. EDITORIAL: Richard Palmer: celebrating 37 years with Journal of Physics: Condensed Matter Richard Palmer: celebrating 37 years with Journal of Physics: Condensed Matter

    NASA Astrophysics Data System (ADS)

    Ferry, David

    2009-01-01

    It is with a great deal of both happiness and sadness that I have to announce that we are losing one of the real strengths of the Journal of Physics: Condensed Matter (JPCM). Dr Richard Palmer, our Senior Publisher, announced his retirement, and this issue marks the first without his involvement. Of course, we are happy that he will get to enjoy his retirement, but we are sad to lose such a valuable member of our team. Richard first started work at IOP Publishing in March 1971 as an Editorial Assistant with Journal of Physics B: Atomic and Molecular Physics. After a few months, he transferred to Journal of Physics C: Solid State Physics. During his first year, he was sent on a residential publishing training course and asked to sign an undertaking to stay at IOP Publishing for at least two years. Although Richard refused to sign, as he did not want to commit himself, he has remained with the journal since then. The following year, the Assistant Editor of Journal of Physics C: Solid State Physics, Malcolm Haines, walked out without notice in order to work on his family vineyard in France, and Richard stepped into the breach. In those days, external editors had a much more hands-on role in IOP Publishing and he had to travel to Harwell to be interviewed by Alan Lidiard, the Honorary Editor of Journal of Physics C: Solid State Physics, before being given the job of Assistant Editor permanently. I am told that in those days the job consisted mainly of editing and proofreading and peer review. There was no journal development work. At some point in the early 1980s, production and peer review were split into separate departments and Richard then headed a group of journals consisting of Journal of Physics C: Solid State Physics, Journal of Physics D: Applied Physics and Journal of Physics F: Metal Physics, Semiconductor Science and Technology, Superconductor Science and Technology, Plasma Physics and Controlled Fusion, and later Nanotechnology and Modelling and Simulation

  8. High-resolution 3-T MRI of the triangular fibrocartilage complex in the wrist: injury pattern and MR features.

    PubMed

    Zhan, Huili; Zhang, Huibo; Bai, Rongjie; Qian, Zhanhua; Liu, Yue; Zhang, Heng; Yin, Yuming

    2017-12-01

    To investigate if using high-resolution 3-T MRI can identify additional injuries of the triangular fibrocartilage complex (TFCC) beyond the Palmer classification. Eighty-six patients with surgically proven TFCC injury were included in this study. All patients underwent high-resolution 3-T MRI of the injured wrist. The MR imaging features of TFCC were analyzed according to the Palmer classification. According to the Palmer classification, 69 patients could be classified as having Palmer injuries (52 had traumatic tears and 17 had degenerative tears). There were 17 patients whose injuries could not be classified according to the Palmer classification: 13 had volar or dorsal capsular TFC detachment and 4 had a horizontal tear of the articular disk. Using high-resolution 3-T MRI, we have not only found all the TFCC injuries described in the Palmer classification, additional injury types were found in this study, including horizontal tear of the TFC and capsular TFC detachment. We propose the modified Palmer classification and add the injury types that were not included in the original Palmer classification.

  9. Refining economics of U.S. gasoline: octane ratings and ethanol content.

    PubMed

    Hirshfeld, David S; Kolb, Jeffrey A; Anderson, James E; Studzinski, William; Frusti, James

    2014-10-07

    Increasing the octane rating of the U.S. gasoline pool (currently ∼ 93 Research Octane Number (RON)) would enable higher engine efficiency for light-duty vehicles (e.g., through higher compression ratio), facilitating compliance with federal fuel economy and greenhouse gas (GHG) emissions standards. The federal Renewable Fuels Standard calls for increased renewable fuel use in U.S. gasoline, primarily ethanol, a high-octane gasoline component. Linear programming modeling of the U.S. refining sector was used to assess the effects on refining economics, CO2 emissions, and crude oil use of increasing average octane rating by increasing (i) the octane rating of refinery-produced hydrocarbon blendstocks for oxygenate blending (BOBs) and (ii) the volume fraction (Exx) of ethanol in finished gasoline. The analysis indicated the refining sector could produce BOBs yielding finished E20 and E30 gasolines with higher octane ratings at modest additional refining cost, for example, ∼ 1¢/gal for 95-RON E20 or 97-RON E30, and 3-5¢/gal for 95-RON E10, 98-RON E20, or 100-RON E30. Reduced BOB volume (from displacement by ethanol) and lower BOB octane could (i) lower refinery CO2 emissions (e.g., ∼ 3% for 98-RON E20, ∼ 10% for 100-RON E30) and (ii) reduce crude oil use (e.g., ∼ 3% for 98-RON E20, ∼ 8% for 100-RON E30).

  10. Connectomic Reconstruction of the Inner Plexiform Layer in the Mouse Retina

    DTIC Science & Technology

    2013-08-08

    PROGRAM ELEMENT NUMBER 611103 6.AUTHORS Sd. PROJECT NUMBER Moritz Helmstaedter, Kevin L. Briggman, Srinivas C . Tw-aga, Viren Jain, H. Sebastian...LIMITATION OF a. REPORT b . ABSTRACT c . THIS PAGE ABSTRACT uu uu uu uu Models, Biological* New-opillphysiology 1S . NUMBER OF PAGES .. 19a. NAME...mouse retina Moritz Helmstaedter1{, Kevin L. Briggman1{, Srinivas C . Turaga2{, Viren Jain2{, H. Sebastian Seung2 & Winfried Denk1 Comprehensivehigh

  11. A Role for Epigenetic Mechanisms in Organ-Specific Breast Cancer Metastasis

    DTIC Science & Technology

    2010-05-01

    of origin. The neovasculature of tumors is typically leaky (Carmeliet and Jain, 2000; Rafii et al., 2003), a feature that would facilitate not only...and therapy selection in esophageal cancer. Cancer Cell 13, 441- 453. Rafii , S., Avecilla, S.T., and Jin, D.K. (2003). Tumor vasculature address book...origin. The neovasculature of tumors is typically leaky (Carmeliet and Jain, 2000; Rafii et al., 2003), a feature that would facilitate not only the

  12. Palmer LTER: Patterns of distribution of five dominant zooplankton species in the epipelagic zone west of the Antarctic Peninsula, 1993 2004

    NASA Astrophysics Data System (ADS)

    Ross, Robin M.; Quetin, Langdon B.; Martinson, Douglas G.; Iannuzzi, Rich A.; Stammerjohn, Sharon E.; Smith, Raymond C.

    2008-09-01

    Variability in the temporal-spatial distribution and abundance of zooplankton was documented each summer on the Palmer Long-Term Ecological Research (LTER) grid west of the Antarctic Peninsula between Anvers and Adelaide Islands during a 12-yr time series. Oblique tows to 120 m with a 2×2 m fixed-frame net were made at about 50 stations each January/February between 1993 and 2004. The numerically dominant macro- and mesozooplanktonic species >2 mm included three species of euphausiids ( Euphausia superba, Antarctic krill; Thysanoëssa macrura; Euphausia crystallorophias, ice krill), a shelled pteropod ( Limacina helicina), and a salp ( Salpa thompsoni). Life cycles, life spans, and habitat varied among these species. Abundance data from each year were allocated to 100 km by 20 km (alongshore by on/offshore) grid cells centered on cardinal transect lines and stations within the Palmer LTER grid. The long-term mean or climatology and means for each year were used to calculate annual anomalies across the grid. Principal components analysis (PCA) was used to analyze for patterns and trends in the temporal-spatial variability of the five species. Questions included whether there are groups of species with similar patterns, and whether population cycles, species interactions or seasonal sea-ice parameters were correlated with detected patterns. Patterns in the climatology were distinct, and matched those of physical parameters. Common features included higher abundance in the north than in the south, independent of the cross-shelf gradients, and cross-shelf gradients with higher abundance either inshore ( E. crystallorophias) or offshore ( S. thompsoni). Anomalies revealed either cycles in the population, as episodic recruitment in Antarctic krill, or changes in anomaly pattern between the first and second half of the sampling period. The 1998 year, which coincided with a rapid change from a negative to a positive phase in the SOI, emerged as a year with either

  13. UV-vis spectroscopy study of plasma-activated water: Dependence of the chemical composition on plasma exposure time and treatment distance

    NASA Astrophysics Data System (ADS)

    Oh, Jun-Seok; Szili, Endre J.; Ogawa, Kotaro; Short, Robert D.; Ito, Masafumi; Furuta, Hiroshi; Hatta, Akimitsu

    2018-01-01

    Plasma-activated water (PAW) is receiving much attention in biomedical applications because of its reported potent bactericidal properties. Reactive oxygen and nitrogen species (RONS) that are generated in water upon plasma exposure are thought to be the key components in PAW that destroy bacterial and cancer cells. In addition to developing applications for PAW, it is also necessary to better understand the RONS chemistry in PAW in order to tailor PAW to achieve a specific biological response. With this in mind, we previously developed a UV-vis spectroscopy method using an automated curve fitting routine to quantify the changes in H2O2, NO2 -, NO3 - (the major long-lived RONS in PAW), and O2 concentrations. A major advantage of UV-vis is that it can take multiple measurements during plasma activation. We used the UV-vis procedure to accurately quantify the changes in the concentrations of these RONS and O2 in PAW. However, we have not yet provided an in-depth commentary of how we perform the curve fitting procedure or its implications. Therefore, in this study, we provide greater detail of how we use the curve fitting routine to derive the RONS and O2 concentrations in PAW. PAW was generated by treatment with a helium plasma jet. In addition, we employ UV-vis to study how the plasma jet exposure time and treatment distance affect the RONS chemistry and amount of O2 dissolved in PAW. We show that the plasma jet exposure time principally affects the total RONS concentration, but not the relative ratios of RONS, whereas the treatment distance affects both the total RONS concentration and the relative RONS concentrations.

  14. Plasma cell treatment device Plasma-on-Chip: Monitoring plasma-generated reactive species in microwells

    PubMed Central

    Oh, Jun-Seok; Kojima, Shinya; Sasaki, Minoru; Hatta, Akimitsu; Kumagai, Shinya

    2017-01-01

    We have developed a plasma cell treatment device called Plasma-on-Chip that enables the real-time monitoring of a single cell culture during plasma treatment. The device consists of three parts: 1) microwells for cell culture, 2) a microplasma device for generating reactive oxygen and nitrogen species (RONS) for use in cell treatment, and 3) through-holes (microchannels) that connect each microwell with the microplasma region for RONS delivery. Here, we analysed the delivery of the RONS to the liquid culture medium stored in the microwells. We developed a simple experimental set-up using a microdevice and applied in situ ultraviolet absorption spectroscopy with high sensitivity for detecting RONS in liquid. The plasma-generated RONS were delivered into the liquid culture medium via the through-holes fabricated into the microdevice. The RONS concentrations were on the order of 10–100 μM depending on the size of the through-holes. In contrast, we found that the amount of dissolved oxygen was almost constant. To investigate the process of RONS generation, we numerically analysed the gas flow in the through-holes. We suggest that the circulating gas flow in the through-holes promotes the interaction between the plasma (ionised gas) and the liquid, resulting in enhanced RONS concentrations. PMID:28176800

  15. Export of a Toxoplasma gondii Rhoptry Neck Protein Complex at the Host Cell Membrane to Form the Moving Junction during Invasion

    PubMed Central

    Poncet, Joël; Dubremetz, Jean-François; Lebrun, Maryse

    2009-01-01

    One of the most conserved features of the invasion process in Apicomplexa parasites is the formation of a moving junction (MJ) between the apex of the parasite and the host cell membrane that moves along the parasite and serves as support to propel it inside the host cell. The MJ was, up to a recent period, completely unknown at the molecular level. Recently, proteins originated from two distinct post-Golgi specialised secretory organelles, the micronemes (for AMA1) and the neck of the rhoptries (for RON2/RON4/RON5 proteins), have been shown to form a complex. AMA1 and RON4 in particular, have been localised to the MJ during invasion. Using biochemical approaches, we have identified RON8 as an additional member of the complex. We also demonstrated that all RON proteins are present at the MJ during invasion. Using metabolic labelling and immunoprecipitation, we showed that RON2 and AMA1 were able to interact in the absence of the other members. We also discovered that all MJ proteins are subjected to proteolytic maturation during trafficking to their respective organelles and that they could associate as non-mature forms in vitro. Finally, whereas AMA1 has previously been shown to be inserted into the parasite membrane upon secretion, we demonstrated, using differential permeabilization and loading of RON-specific antibodies into the host cell, that the RON complex is targeted to the host cell membrane, where RON4/5/8 remain associated with the cytoplasmic face. Globally, these results point toward a model of MJ organization where the parasite would be secreting and inserting interacting components on either side of the MJ, both at the host and at its own plasma membranes. PMID:19247437

  16. SAF-RON GOLD

    EPA Pesticide Factsheets

    Technical product bulletin: this dispersant used in oil spill cleanups can be applied by aerial or boat sprayer. A recommended dispersant to water ratio of 1:40 can be used for most spills. Ratios are dependent upon type of oil and weather conditions.

  17. Seismic and mechanical studies of the artificially triggered rockfall at the Mount Néron (French Alps, December 2011)

    NASA Astrophysics Data System (ADS)

    Bottelin, P.; Jongmans, D.; Daudon, D.; Mathy, A.; Helmstetter, A.; Bonilla-Sierra, V.; Cadet, H.; Amitrano, D.; Richefeu, V.; Lorier, L.; Baillet, L.; Villard, P.; Donzé, F.

    2014-02-01

    The eastern limestone cliff of Mount Néron (French Alps) was the theatre of two medium-size rockfalls between summer and winter 2011. On 14 August 2011, a ~ 2000 m3 rock compartment detached from the cliff, fell 100 m below and propagated down the slope. Although most of the fallen rocks deposited in the upper part of the slope, about 15 meter-size blocks were stopped by a ditch and an earthen barrier after a runout of 800 m. An unstable overhanging ~ 2600 m3 compartment remained attached to the cliff and was blasted on 13 December 2011. During this artificially triggered event, 7 blocks reached the same ditch, with volumes ranging from 0.8 to 12 m3. A semi-permanent seismic array located about 2.5 km from the site recorded the two events, providing a unique opportunity to understand and to compare the seismic phases generated during natural and artificially triggered rockfalls. Both events have signal duration of ~ 100 s with comparable maximum amplitudes recorded at large distances (computed local magnitude of 1.14 and 1.05, respectively), most of the energy lying below 20 Hz. Remote sensing techniques (photogrammetry and LiDAR) were employed before and after the provoked rockfall, allowing the volume and fracturing to be characterized. This event was filmed by two video cameras and the generated ground motions were recorded using two temporary 3C seismic sensors and 3 seismic arrays deployed at the slope toe. Movie and seismogram processing provided estimates of the propagation velocity during the successive rockfall phases, which ranges from 12 m s-1 to 30 m s-1. The main seismic phases were obtained from combined video and seismic signal analyses. The two most energetic phases are related to the ground impact of fallen material after free-fall, and to individual rock block impacts into the ditch and the earthen barrier. These two phases are characterized by similar low-frequency content but show very different particle motions. The discrete element technique

  18. PREFACE: Celebrating 20 years of Journal of Physics: Condensed Matter—in honour of Richard Palmer Celebrating 20 years of Journal of Physics: Condensed Matter—in honour of Richard Palmer

    NASA Astrophysics Data System (ADS)

    Ferry, David; Dowben, Peter; Inglesfield, John

    2009-11-01

    This year marks the 20th anniversary of the launch of Journal of Physics: Condensed Matter in 1989. The journal was formed from the merger of Journal of Physics C: Solid State Physics and Journal of Physics F: Metal Physics which had separated in 1971. In the 20 years since its launch, Journal of Physics: Condensed Matter has more than doubled in size, while raising standards. Indeed, Journal of Physics: Condensed Matter has become one of the leading scientific journals for our field. This could not have occurred without great leadership at the top. No one has been more responsible for this growth in both size and quality than our Senior Publisher, Richard Palmer. Richard first started work at IOP in March 1971 as an Editorial Assistant with J. Phys. B After a few months, he transferred to J. Phys.C The following year, the Assistant Editor of J. Phys. C, Malcolm Haines, left suddenly in order to work on his family vineyard in France, and Richard stepped into the breach. In those days, external editors had a much more hands-on role in IOP Publishing and he had to travel to Harwell to be interviewed by Alan Lidiard, the Honorary Editor of J. Phys. C, before being given the job of Assistant Editor permanently. Since J. Phys. C and J. Phys. F re-merged to form Journal of Physics: Condensed Matter, Richard gradually shed his other journal responsibilities, except for Reports on Progress in Physics, to build up Journal of Physics: Condensed Matter. He has worked closely with four Editors-in-Chief of J. Phys. C and five of Journal of Physics: Condensed Matter. When Richard announced his retirement this past winter, we met it with a great deal of both happiness and sadness. Of course, we are happy that he is going to be allowed to enjoy his retirement, but we remain very sad to lose such a valuable member of our team, especially the one who had provided the heart and soul of the journal over its 20 years. We will be able to rely upon the team which Richard ably trained as

  19. Population Genetic Structure in Glyphosate-Resistant and -Susceptible Palmer Amaranth (Amaranthus palmeri) Populations Using Genotyping-by-sequencing (GBS)

    PubMed Central

    Küpper, Anita; Manmathan, Harish K.; Giacomini, Darci; Patterson, Eric L.; McCloskey, William B.; Gaines, Todd A.

    2018-01-01

    Palmer amaranth (Amaranthus palmeri) is a major weed in United States cotton and soybean production systems. Originally native to the Southwest, the species has spread throughout the country. In 2004 a population of A. palmeri was identified with resistance to glyphosate, a herbicide heavily relied on in modern no-tillage and transgenic glyphosate-resistant (GR) crop systems. This project aims to determine the degree of genetic relatedness among eight different populations of GR and glyphosate-susceptible (GS) A. palmeri from various geographic regions in the United States by analyzing patterns of phylogeography and diversity to ascertain whether resistance evolved independently or spread from outside to an Arizona locality (AZ-R). Shikimic acid accumulation and EPSPS genomic copy assays confirmed resistance or susceptibility. With a set of 1,351 single nucleotide polymorphisms (SNPs), discovered by genotyping-by-sequencing (GBS), UPGMA phylogenetic analysis, principal component analysis, Bayesian model-based clustering, and pairwise comparisons of genetic distances were conducted. A GR population from Tennessee and two GS populations from Georgia and Arizona were identified as genetically distinct while the remaining GS populations from Kansas, Arizona, and Nebraska clustered together with two GR populations from Arizona and Georgia. Within the latter group, AZ-R was most closely related to the GS populations from Kansas and Arizona followed by the GR population from Georgia. GR populations from Georgia and Tennessee were genetically distinct from each other. No isolation by distance was detected and A. palmeri was revealed to be a species with high genetic diversity. The data suggest the following two possible scenarios: either glyphosate resistance was introduced to the Arizona locality from the east, or resistance evolved independently in Arizona. Glyphosate resistance in the Georgia and Tennessee localities most likely evolved separately. Thus, modern farmers

  20. A method for the topographical identification and quantification of high frequency oscillations in intracranial electroencephalography recordings

    PubMed Central

    Waldman, Zachary J.; Shimamoto, Shoichi; Song, Inkyung; Orosz, Iren; Bragin, Anatol; Fried, Itzhak; Engel, Jerome; Staba, Richard; Sperling, Michael R.; Weiss, Shennan A.

    2018-01-01

    Objective To develop a reliable software method using a topographic analysis of time-frequency plots to distinguish ripple (80–200 Hz) oscillations that are often associated with EEG sharp waves or spikes (RonS) from sinusoid-like waveforms that appear as ripples but correspond with digital filtering of sharp transients contained in the wide bandwidth EEG. Methods A custom algorithm distinguished true from false ripples in one second intracranial EEG (iEEG) recordings using wavelet convolution, identifying contours of isopower, and categorizing these contours into sets of open or closed loop groups. The spectral and temporal features of candidate groups were used to classify the ripple, and determine its duration, frequency, and power. Verification of detector accuracy was performed on the basis of simulations, and visual inspection of the original and band-pass filtered signals. Results The detector could distinguish simulated true from false ripple on spikes (RonS). Among 2934 visually verified trials of iEEG recordings and spectrograms exhibiting RonS the accuracy of the detector was 88.5% with a sensitivity of 81.8% and a specificity of 95.2%. The precision was 94.5% and the negative predictive value was 84.0% (N = 12). Among, 1,370 trials of iEEG recording exhibiting RonS that were reviewed blindly without spectrograms the accuracy of the detector was 68.0%, with kappa equal to 0.01 ± 0.03. The detector successfully distinguished ripple from high spectral frequency ‘fast ripple’ oscillations (200–600 Hz), and characterize ripple duration and spectral frequency and power. The detector was confounded by brief bursts of gamma (30–80 Hz) activity in 7.31 ± 6.09% of trials, and in 30.2 ± 14.4% of the true RonS detections ripple duration was underestimated. Conclusions Characterizing the topographic features of a time-frequency plot generated by wavelet convolution is useful for distinguishing true oscillations from false oscillations generated by

  1. Old Dad Chiro: his thoughts, words, and deeds

    PubMed Central

    Brown, Myron D.

    2010-01-01

    Objective This article offers the author's opinions about some of the thoughts, words, and deeds of the profession's founder, Daniel David Palmer. Discussion Reviewing D.D. Palmer's writings is challenging because he was the discoverer and founder of a developing profession and therefore his thoughts and words were rapidly evolving. Statements made by Palmer without judicious consideration of context could easily be misunderstood. Conclusion D.D. Palmer was individualistic and enigmatic. This commentary provides a look at the whole in an attempt to reveal the character and spirit of the founder. PMID:22693470

  2. Climate conditions and drought assessment with the Palmer Drought Severity Index in Iran: evaluation of CORDEX South Asia climate projections (2070-2099)

    NASA Astrophysics Data System (ADS)

    Senatore, Alfonso; Hejabi, Somayeh; Mendicino, Giuseppe; Bazrafshan, Javad; Irannejad, Parviz

    2018-03-01

    Climate change projections were evaluated over both the whole Iran and six zones having different precipitation regimes considering the CORDEX South Asia dataset, for assessing space-time distribution of drought occurrences in the future period 2070-2099 under RCP4.5 scenario. Initially, the performances of eight available CORDEX South Asia Regional Climate Models (RCMs) were assessed for the baseline period 1970-2005 through the GPCC v.7 precipitation dataset and the CFSR temperature dataset, which were previously selected as the most reliable within a set of five global datasets compared to 41 available synoptic stations. Though the CCLM RCM driven by the MPI-ESM-LR General Circulation Model is in general the most suitable for temperature and, together with the REMO 2009 RCM also driven by MPI-ESM-LR, for precipitation, their performances do not overwhelm other models for every season and zone in which Iranian territory was divided according to a principal component analysis approach. Hence, a weighting approach was tested and adopted to take into account useful information from every RCM in each of the six zones. The models resulting more reliable compared to current climate show a strong precipitation decrease. Weighted average predicts an overall yearly precipitation decrease of about 20%. Temperature projections provide a mean annual increase of 2.4 °C. Future drought scenarios were depicted by means of the self-calibrating version of the Palmer drought severity index (SC-PDSI) model. Weighted average predicts a sharp drying that can be configured as a real shift in mean climate conditions, drastically affecting water resources of the country.

  3. Detection of anomalous crop condition and soil variability mapping using a 26 year Landsat record and the Palmer crop moisture index

    NASA Astrophysics Data System (ADS)

    Venteris, E. R.; Tagestad, J. D.; Downs, J. L.; Murray, C. J.

    2015-07-01

    Cost-effective and reliable vegetation monitoring methods are needed for applications ranging from traditional agronomic mapping, to verifying the safety of geologic injection activities. A particular challenge is defining baseline crop conditions and subsequent anomalies from long term imagery records (Landsat) in the face of large spatiotemporal variability. We develop a new method for defining baseline crop response (near peak growth) using the normalized difference vegetation index (NDVI) from 26 years (1986-2011) of Landsat data for 400 km2 surrounding a planned geologic carbon sequestration site near Jacksonville, Illinois. The normal score transform (yNDVI) was applied on a field by field basis to accentuate spatial patterns and level differences due to planting times. We tested crop type and soil moisture (Palmer crop moisture index (CMI)) as predictors of expected crop condition. Spatial patterns in yNDVI were similar between corn and soybeans - the two major crops. Linear regressions between yNDVI and the cumulative CMI (CCMI) exposed complex interactions between crop condition, field location (topography and soils), and annual moisture. Wet toposequence positions (depressions) were negatively correlated to CCMI and dry positions (crests) positively correlated. However, only 21% of the landscape showed a statistically significant (p < 0.05) linear relationship. To map anomalous crop conditions, we defined a tolerance interval based on yNDVI statistics. Tested on an independent image (2013), 63 of 1483 possible fields showed unusual crop condition. While the method is not directly suitable for crop health assessment, the spatial patterns in correlation between yNDVI and CCMI have potential applications for pest damage detection and edaphological soil mapping, especially in the developing world.

  4. Variant RONΔ160 of the RON receptor tyrosine kinase promotes the growth and invasion in vitro and in vivo in gastric cancer cell lines.

    PubMed

    Zhou, Dong-Hui; Li, Chao; Yang, Li-Na

    2015-01-01

    Recepteur d'origine nantais (RON) is a receptor tyrosine kinase whose overexpression has been observed in human gastric cancers. This study aimed to determine whether overexpression of the variant RONΔ160 could induce tumorigenicity of gastric cancer cells in vitro or in vivo, and whether its specific small molecule inhibitor (Compound I) could inhibit the effect of RONΔ160. We constructed human gastric cancer cell line MGC-803 that was stably transfected with a recombinant plasmid expressing RONΔ160, and the effect of RONΔ160 overexpression and macrophage-stimulating protein (MSP) activation on proliferation, migration and invasion abilities of MGC-803 cells were evaluated. Tumor-bearing mice with gastric cancer cells were used to analyze the effects of RONΔ160 overexpression and Compound I on implanted tumor growth. In vitro, overexpression of RONΔ160 in MGC-803 cells resulted changes to their cell morphology, and promoted cell proliferation, migration and invasion. In addition, overexpression of RONΔ160 increased the proportion of cells in the S phase. The effect of RONΔ160 was significantly enhanced by induction of MSP inducing (p < 0.05). In vivo, RONΔ160 promoted the growth of MGC-803 cells in nude mice, including increased tumor size and weight, and lower tumor incubation period. The Compound I inhibited the tumorigenic abilities of RONΔ160 (p <0.05). The results indicate that overexpression of the variant RONΔ160 altered the phenotype and tumorigenicity of MGC-803 cells. Its specific small molecule inhibitor could inhibit the effect of RONΔ160. Therefore, the variant RONΔ160 may become a potential therapeutic target for gastric cancer.

  5. Biological Activities of Reactive Oxygen and Nitrogen Species: Oxidative Stress versus Signal Transduction

    PubMed Central

    Weidinger, Adelheid; Kozlov, Andrey V.

    2015-01-01

    In the past, reactive oxygen and nitrogen species (RONS) were shown to cause oxidative damage to biomolecules, contributing to the development of a variety of diseases. However, recent evidence has suggested that intracellular RONS are an important component of intracellular signaling cascades. The aim of this review was to consolidate old and new ideas on the chemical, physiological and pathological role of RONS for a better understanding of their properties and specific activities. Critical consideration of the literature reveals that deleterious effects do not appear if only one primary species (superoxide radical, nitric oxide) is present in a biological system, even at high concentrations. The prerequisite of deleterious effects is the formation of highly reactive secondary species (hydroxyl radical, peroxynitrite), emerging exclusively upon reaction with another primary species or a transition metal. The secondary species are toxic, not well controlled, causing irreversible damage to all classes of biomolecules. In contrast, primary RONS are well controlled (superoxide dismutase, catalase), and their reactions with biomolecules are reversible, making them ideal for physiological/pathophysiological intracellular signaling. We assume that whether RONS have a signal transducing or damaging effect is primarily defined by their quality, being primary or secondary RONS, and only secondly by their quantity. PMID:25884116

  6. Constructing a philosophy of chiropractic: evolving worldviews and postmodern core☆

    PubMed Central

    Senzon, Simon A.

    2011-01-01

    Objective The purpose of this article is to explore the postmodern, postrational, and postconventional core of DD Palmer's self-sense and philosophy. Discussion DD Palmer's self and philosophy can be viewed as a reaction to the self of modernity and its challenges of a fracture between mind and body, spirit, and nature. It is argued that Palmer's solution to these vexing problems facing the modern self was to use postrational and postconventional logic to overcome the dualisms. His philosophy resonates with similar postrational approaches, most notably, the German idealist Schelling. Conclusion It is argued that Palmer was one of the first postrational individuals in America and that chiropractic was an attempt at the first postrational health profession. PMID:22693480

  7. Constructing a philosophy of chiropractic: evolving worldviews and postmodern core().

    PubMed

    Senzon, Simon A

    2011-12-01

    The purpose of this article is to explore the postmodern, postrational, and postconventional core of DD Palmer's self-sense and philosophy. DD Palmer's self and philosophy can be viewed as a reaction to the self of modernity and its challenges of a fracture between mind and body, spirit, and nature. It is argued that Palmer's solution to these vexing problems facing the modern self was to use postrational and postconventional logic to overcome the dualisms. His philosophy resonates with similar postrational approaches, most notably, the German idealist Schelling. It is argued that Palmer was one of the first postrational individuals in America and that chiropractic was an attempt at the first postrational health profession.

  8. Operation Junction City, Vietnam, 1967

    DTIC Science & Technology

    1983-06-03

    schoul of thought is well developed in the memoirs of General William C . Westmoreland (A Soldier Reports) and by Dave R. Palmer in his Summons of the...high-level US personnel, General Maxwell D. Taylor became Ambassador to South Vietnam and General William C . Westmoreland took over as the Coimmander...Palmer, p. 71. 16. William C . Westmoreland, A Soldier Reports (Garden City, New York: Doubleday, 1976), p. 185. 17. Westmoreland, p. 320. 18. Palmer

  9. Economic and environmental benefits of higher-octane gasoline.

    PubMed

    Speth, Raymond L; Chow, Eric W; Malina, Robert; Barrett, Steven R H; Heywood, John B; Green, William H

    2014-06-17

    We quantify the economic and environmental benefits of designing U.S. light-duty vehicles (LDVs) to attain higher fuel economy by utilizing higher octane (98 RON) gasoline. We use engine simulations, a review of experimental data, and drive cycle simulations to estimate the reduction in fuel consumption associated with using higher-RON gasoline in individual vehicles. Lifecycle CO2 emissions and economic impacts for the U.S. LDV fleet are estimated based on a linear-programming refinery model, a historically calibrated fleet model, and a well-to-wheels emissions analysis. We find that greater use of high-RON gasoline in appropriately tuned vehicles could reduce annual gasoline consumption in the U.S. by 3.0-4.4%. Accounting for the increase in refinery emissions from production of additional high-RON gasoline, net CO2 emissions are reduced by 19-35 Mt/y in 2040 (2.5-4.7% of total direct LDV CO2 emissions). For the strategies studied, the annual direct economic benefit is estimated to be $0.4-6.4 billion in 2040, and the annual net societal benefit including the social cost of carbon is estimated to be $1.7-8.8 billion in 2040. Adoption of a RON standard in the U.S. in place of the current antiknock index (AKI) may enable refineries to produce larger quantities of high-RON gasoline.

  10. The Clustering of Galaxies and Dark Matter at Intermediate Redshifts

    NASA Technical Reports Server (NTRS)

    Jain, Bhuvnesh; Szalay, Alexander

    2003-01-01

    Theoretical work in the study of weak lensing was begun while the Scientific PI (Jain) was at the Johns Hopkins University. A new postdoctoral fellow, Rita Kim, was hired to work for 0.5 years on the proposed research. She was unable to join JHU until March 2001 owing to delays in her PhD work. Meanwhile PI Jain moved to the University of Pennsylvania in January 2001. Owing to the above circumstances, the work for the proposed research was delayed and was expected to be carried out in the remainder of 2001. New measures of lensing based on the magnification effect were to be investigated by Drs. Jain and Kim. The simulations needed to test the analytical computations were already in place; hence the work was expected to proceed fairly rapidly. Owing to the close proximity of JHU and UPenn, the collaborative work was expected to proceed smoothly. It was requested therefore that the funds for the first grant year (2000-2001) be transferred to the second year. Part of the funding was spent at JHU on the salary for the Postdoctoral Fellow, Rita Kim, and the remainder at the University of Pennsylvania. The work from this grant is incomplete and will be continued under another grant.

  11. Resimulation of noise: a precision estimator for least square error curve-fitting tested for axial strain time constant imaging

    NASA Astrophysics Data System (ADS)

    Nair, S. P.; Righetti, R.

    2015-05-01

    Recent elastography techniques focus on imaging information on properties of materials which can be modeled as viscoelastic or poroelastic. These techniques often require the fitting of temporal strain data, acquired from either a creep or stress-relaxation experiment to a mathematical model using least square error (LSE) parameter estimation. It is known that the strain versus time relationships for tissues undergoing creep compression have a non-linear relationship. In non-linear cases, devising a measure of estimate reliability can be challenging. In this article, we have developed and tested a method to provide non linear LSE parameter estimate reliability: which we called Resimulation of Noise (RoN). RoN provides a measure of reliability by estimating the spread of parameter estimates from a single experiment realization. We have tested RoN specifically for the case of axial strain time constant parameter estimation in poroelastic media. Our tests show that the RoN estimated precision has a linear relationship to the actual precision of the LSE estimator. We have also compared results from the RoN derived measure of reliability against a commonly used reliability measure: the correlation coefficient (CorrCoeff). Our results show that CorrCoeff is a poor measure of estimate reliability for non-linear LSE parameter estimation. While the RoN is specifically tested only for axial strain time constant imaging, a general algorithm is provided for use in all LSE parameter estimation.

  12. Constructing a philosophy of chiropractic: evolving worldviews and modern foundation☆

    PubMed Central

    Senzon, Simon A.

    2011-01-01

    Objective The purpose of this article is to trace the foundations of DD Palmer's sense of self and philosophy of chiropractic to its sources in modern Western philosophy as well as current metatheories about modernity. Discussion DD Palmer's sense of self was indicative of a modern self. A modern self is characterized as a self that developed after the Western Enlightenment and must come to terms with the insights of modernity such as Cartesian dualism, Spinoza's substance, Rousseau's expressivism, and Kant's critiques. It is argued that Palmer's philosophy can be viewed as part of the this tradition alongside his involvement in the 19th century American metaphysical religious culture, which was itself a response to these challenges of the modern self of modernity. Conclusion Palmer's development of chiropractic and its philosophy was a reaction to the challenges and promises of modernity. PMID:22693479

  13. Constructing a philosophy of chiropractic: evolving worldviews and modern foundation().

    PubMed

    Senzon, Simon A

    2011-12-01

    The purpose of this article is to trace the foundations of DD Palmer's sense of self and philosophy of chiropractic to its sources in modern Western philosophy as well as current metatheories about modernity. DD Palmer's sense of self was indicative of a modern self. A modern self is characterized as a self that developed after the Western Enlightenment and must come to terms with the insights of modernity such as Cartesian dualism, Spinoza's substance, Rousseau's expressivism, and Kant's critiques. It is argued that Palmer's philosophy can be viewed as part of the this tradition alongside his involvement in the 19th century American metaphysical religious culture, which was itself a response to these challenges of the modern self of modernity. Palmer's development of chiropractic and its philosophy was a reaction to the challenges and promises of modernity.

  14. Impact of irrigation rate on pre-emergence herbicide activity

    USDA-ARS?s Scientific Manuscript database

    The importance of preemergence herbicide applications in cotton has increased since the development of glyphosate-resistant Palmer amaranth (Amaranthus palmeri). Cotton producers are relying on residual herbicides for control of Palmer amaranth, as postemergence options are limited or ineffective. S...

  15. Obituary: Ronald Cecil Stone, 1946-2005

    NASA Astrophysics Data System (ADS)

    Monet, Alice Kay Babcock

    2006-12-01

    Ronald C. Stone, an astronomer at the US Naval Observatory Flagstaff Station, passed away on 10 September 2005 in Downer's Grove, IL, following a valiant struggle with cancer. He was fifty-nine years old. Ron was born on 9 June 1946 in Seattle, Washington, to Helen (Vocelka) and Cecil Stone. His father was a World War II veteran who attended college on the GI Bill and became a mechanical engineer. He and his wife raised three sons: Dwight, Ronald, and Gavin. They lived in a number of locations across the U.S. before settling at last in Downer's Grove when Ron was in the fourth grade. Ron's interest in astronomy began when he was given a toy planetarium projector while still in grade school, and later a small telescope. In high school, he also built his own telescope, grinding the 6-inch mirror by hand. He completed grade school and high school in Downer's Grove and did his undergraduate studies at the University of Illinois at Urbana-Champaign, majoring in astronomy and physics and graduating cum laude in 1968. The following year, he was drafted into the U.S. Army and served for two years, including a stint in Vietnam. Although his primary assignment was auditing, he was also involved in the defense of the Long Binh base in Vietnam. He was honorably discharged from the service in 1971 and enrolled that fall at the University of Chicago. While a graduate student working with Bill van Altena, Ron developed his life long interest in the field of astrometry. Van Altena recalls him as "a quiet and cheerful student who wanted to learn, and [who] worked hard to understand the intricacies of astrometry... deriving the most precise proper motions from the 40-inch [Yerkes] refractor plates." Working at Yerkes Observatory in Williams Bay, Wisconsin, he completed a thesis entitled, "Mean Secular Parallax at Low Galactic Latitude." While living in Wisconsin, Ron also became engaged to Ellen Mickel, and the two were married at his parents' home in Downer's Grove. After earning

  16. ECUT: Energy Conversion and Utilization Technologies program. Industry, university and research interest in the US Department of Energy ECUT biocatalysis research activity

    NASA Technical Reports Server (NTRS)

    Wilcox, R. E.

    1983-01-01

    The results of a Research Opportunity Notice (RON) disseminated by the Jet Propulsion Laboratory for the U.S. Department of Energy Conversion and Utilization Technologies (ECUT) Program's Biocatalysis Research Activity are presented. The RON was issued in late April of 1983 and solicited expressions of interest from petrochemical and chemical companies, bioengineering firms, biochemical engineering consultants, private research laboratories, and universities for participating in a federal research program to investigate potential applications of biotechnology in producing chemicals. The RON results indicate that broad interest exists within the nation's industry, universities, and research institutes for the Activity and its planned research and development program.

  17. 78 FR 42975 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-ODVA, Inc.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-18

    ..., UNITED ARAB EMIRATES; and Jain Technology Co., Ltd., Seoul, REPUBLIC OF KOREA, have been added as parties to this venture. Also, Office FA.com Co., Ltd., Tochigi, JAPAN; and Salem Automation Inc., Winston...

  18. 75 FR 5757 - Notice of Availability of Final Environmental Assessment and Finding of No Significant Impact for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-04

    ..., Delta Junction, AK AGENCY: Alaska State Office, Natural Resources Conservation Service, USDA. ACTION..., the State Conservationist (Alaska) found that the project would not result in a significant impact on... Service, Palmer State Office, 800 West Evergreen, Suite 100, Palmer, AK 99645. 2. Natural Resources...

  19. Plan Aggregation for Strong Cyclic Planning in Nondeterministic Domains

    DTIC Science & Technology

    2014-07-02

    Plan Aggregation for Strong Cyclic Planning in Nondeterministic Domains Ron Alforda, Ugur Kuterc, Dana Naub, Robert P. Goldmanc aASEE/NRL...addresses: ronald.alford.ctr@nrl.navy.mil (Ron Alford), ukuter@sift.net ( Ugur Kuter), nau@cs.umd.edu (Dana Nau), rpgoldman@sift.net (Robert P. Goldman

  20. Plan Aggregation for Strong Cyclic Planning in Nondeterministic Domains

    DTIC Science & Technology

    2014-07-23

    ACRONYM(S) ARO 8. PERFORMING ORGANIZATION REPORT NUMBER 19a. NAME OF RESPONSIBLE PERSON 19b. TELEPHONE NUMBER Michael Cox Ron Alford, Ugur Kuter...ScienceDirect Artificial Intelligence www.elsevier.com/locate/artint Plan aggregation for strong cyclic planning in nondeterministic domains Ron Alford a,∗, Ugur

  1. Mitchell Receives 2013 Ronald Greeley Early Career Award in Planetary Science: Response

    NASA Astrophysics Data System (ADS)

    Mitchell, Jonathan L.

    2014-07-01

    I am honored to receive this award in memory of Ron Greeley. Although I did not have the opportunity to know him, I had the pleasure of getting to know his wife, Cynthia, at a luncheon prior to the special awards session at the AGU Fall Meeting. Cynthia is an intelligent and elegant southern woman with a confident gaze. She spoke fondly of Ron and of her sincere respect for his work ethic and dedication to planetary science. What most impressed me, though, was the respect Ron showed to her and the kids by always "giving them the evenings"; no matter how busy things got, Ron always kept his evenings open for Cynthia. This clearly meant the world to her. As a family man, I can only hope that my wife and kids will speak so kindly of me many years from now. I would like to dedicate this award to them in gratitude for their seemingly unconditional love and support.

  2. Baseline Brain Activity Changes in Patients With Single and Relapsing Optic Neuritis.

    PubMed

    Ren, Zhuoqiong; Liu, Yaou; Li, Kuncheng; Duan, Yunyun; Jing, Huang; Liang, Peipeng; Sun, Zheng; Zhang, Xiaojun; Mao, Bei

    2018-01-01

    Purpose : To investigate spontaneous brain activity amplitude alterations in single and relapsing optic neuritis (sON and rON, respectively) and their relationships with clinical variables. Methods : In total, 42 patients with sON, 35 patients with rON and 50 healthy volunteers were recruited. Resting-state functional Magnetic Resonance Imaging (rs-fMRI) scans were acquired for all participants and compared to investigate the changes in the amplitude of low-frequency fluctuations (ALFFs) among the three groups. The relationships between the ALFFs in regions with significant differences in the groups and clinical variables, including the logarithm of minimal angle of resolution (LogMAR), Expanded Disability Status Scale (EDSS) score and disease duration, were further explored. Results : Compared with healthy volunteers, the sON and rON patients showed significantly decreased ALFFs in several regions of the occipital and temporal lobes (i.e., inferior occipital gyrus and superior temporal gyrus; corrected p < 0.01 using AlphaSim). The sON patients showed significantly increased ALFFs in the left caudate and certain regions in the frontal lobes (i.e., medial frontal gyrus), whereas the rON patients showed increased ALFFs in the bilateral inferior temporal gyrus and left medial frontal gyrus (corrected p < 0.01 using AlphaSim). Significantly decreased ALFFs were observed in the right inferior parietal lobule (IPL), left posterior cingulate and precuneus in the rON patients compared with those in the sON patients (corrected p < 0.01 using AlphaSim). Significant correlations were observed between the disease duration and ALFF in the left middle temporal gyrus, left inferior occipital gyrus, right lingual gyrus and right IPL ( p < 0.05). Conclusion : Functional impairment and adaptation occurred in both the sON and rON patients. Impairment mainly involved the occipital cortex, and functional adaptions predominantly occurred in the frontal lobe. Functional damage was more

  3. BioCompoundML: A General Biofuel Property Screening Tool for Biological Molecules Using Random Forest Classifiers

    DOE PAGES

    Whitmore, Leanne S.; Davis, Ryan W.; McCormick, Robert L.; ...

    2016-09-15

    Screening a large number of biologically derived molecules for potential fuel compounds without recourse to experimental testing is important in identifying understudied yet valuable molecules. Experimental testing, although a valuable standard for measuring fuel properties, has several major limitations, including the requirement of testably high quantities, considerable expense, and a large amount of time. This paper discusses the development of a general-purpose fuel property tool, using machine learning, whose outcome is to screen molecules for desirable fuel properties. BioCompoundML adopts a general methodology, requiring as input only a list of training compounds (with identifiers and measured values) and a listmore » of testing compounds (with identifiers). For the training data, BioCompoundML collects open data from the National Center for Biotechnology Information, incorporates user-provided features, imputes missing values, performs feature reduction, builds a classifier, and clusters compounds. BioCompoundML then collects data for the testing compounds, predicts class membership, and determines whether compounds are found in the range of variability of the training data set. We demonstrate this tool using three different fuel properties: research octane number (RON), threshold soot index (TSI), and melting point (MP). Here we provide measures of its success with these properties using randomized train/test measurements: average accuracy is 88% in RON, 85% in TSI, and 94% in MP; average precision is 88% in RON, 88% in TSI, and 95% in MP; and average recall is 88% in RON, 82% in TSI, and 97% in MP. The receiver operator characteristics (area under the curve) were estimated at 0.88 in RON, 0.86 in TSI, and 0.87 in MP. We also measured the success of BioCompoundML by sending 16 compounds for direct RON determination. Finally, we provide a screen of 1977 hydrocarbons/oxygenates within the 8696 compounds in MetaCyc, identifying compounds with high

  4. Forum: Communication Activism Pedagogy. Long-Term Impacts of Communication Activism Pedagogy: Guiding Principles for Future Research

    ERIC Educational Resources Information Center

    Russell, Vincent; Congdon, Mark, Jr.

    2017-01-01

    Communication activism pedagogy (CAP) illuminates an array of ways to intervene into oppressive systems to promote just conditions, and CAP's transformative effects on students and communities have been substantively demonstrated (Frey & Palmer 2014). Yet, Frey and Palmer recognize that "social justice issues are long-term, large-scale…

  5. 50 CFR 100.23 - Rural determinations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 6 2010-10-01 2010-10-01 false Rural determinations. 100.23 Section 100... area—including Kenai, Soldotna, Sterling, Nikiski, Salamatof, Kalifonsky, Kasilof, and Clam Gulch; (6... Pass; (9) Valdez; and (10) Wasilla/Palmer area—including Wasilla, Palmer, Sutton, Big Lake, Houston...

  6. 77 FR 26543 - UGI Storage Company; Notice of Request Under Blanket Authorization

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-04

    ... approximately 3,450 horsepower (hp) of gas fired compression at its existing Palmer Station in Tioga County... compressor units and one 690 hp unit at the Palmer Station located at the downstream terminus of the TL-94...-3-12; 8:45 am] BILLING CODE 6717-01-P ...

  7. Integration of Palmer Drought Severity Index and remote sensing data to simulate wetland water surface from 1910 to 2009 in Cottonwood Lake area, North Dakota

    USGS Publications Warehouse

    Huang, Shengli; Dahal, Devendra; Young, Claudia; Chander, Gyanesh; Liu, Shuguang

    2011-01-01

    Spatiotemporal variations of wetland water in the Prairie Pothole Region are controlled by many factors; two of them are temperature and precipitation that form the basis of the Palmer Drought Severity Index (PDSI). Taking the 196 km2 Cottonwood Lake area in North Dakota as our pilot study site, we integrated PDSI, Landsat images, and aerial photography records to simulate monthly water surface. First, we developed a new Wetland Water Area Index (WWAI) from PDSI to predict water surface area. Second, we developed a water allocation model to simulate the spatial distribution of water bodies at a resolution of 30 m. Third, we used an additional procedure to model the small wetlands (less than 0.8 ha) that could not be detected by Landsat. Our results showed that i) WWAI was highly correlated with water area with an R2 of 0.90, resulting in a simple regression prediction of monthly water area to capture the intra- and inter-annual water change from 1910 to 2009; ii) the spatial distribution of water bodies modeled from our approach agreed well with the water locations visually identified from the aerial photography records; and iii) the R2 between our modeled water bodies (including both large and small wetlands) and those from aerial photography records could be up to 0.83 with a mean average error of 0.64 km2 within the study area where the modeled wetland water areas ranged from about 2 to 14 km2. These results indicate that our approach holds great potential to simulate major changes in wetland water surface for ecosystem service; however, our products could capture neither the short-term water change caused by intensive rainstorm events nor the wetland change caused by human activities.

  8. Impact of Stochastic Parameterization Schemes on Coupled and Uncoupled Climate Simulations with the Community Earth System Model

    NASA Astrophysics Data System (ADS)

    Christensen, H. M.; Berner, J.; Coleman, D.; Palmer, T.

    2015-12-01

    Stochastic parameterizations have been used for more than a decade in atmospheric models to represent the variability of unresolved sub-grid processes. They have a beneficial effect on the spread and mean state of medium- and extended-range forecasts (Buizza et al. 1999, Palmer et al. 2009). There is also increasing evidence that stochastic parameterization of unresolved processes could be beneficial for the climate of an atmospheric model through noise enhanced variability, noise-induced drift (Berner et al. 2008), and by enabling the climate simulator to explore other flow regimes (Christensen et al. 2015; Dawson and Palmer 2015). We present results showing the impact of including the Stochastically Perturbed Parameterization Tendencies scheme (SPPT) in coupled runs of the National Center for Atmospheric Research (NCAR) Community Atmosphere Model, version 4 (CAM4) with historical forcing. The SPPT scheme accounts for uncertainty in the CAM physical parameterization schemes, including the convection scheme, by perturbing the parametrised temperature, moisture and wind tendencies with a multiplicative noise term. SPPT results in a large improvement in the variability of the CAM4 modeled climate. In particular, SPPT results in a significant improvement to the representation of the El Nino-Southern Oscillation in CAM4, improving the power spectrum, as well as both the inter- and intra-annual variability of tropical pacific sea surface temperatures. References: Berner, J., Doblas-Reyes, F. J., Palmer, T. N., Shutts, G. J., & Weisheimer, A., 2008. Phil. Trans. R. Soc A, 366, 2559-2577 Buizza, R., Miller, M. and Palmer, T. N., 1999. Q.J.R. Meteorol. Soc., 125, 2887-2908. Christensen, H. M., I. M. Moroz & T. N. Palmer, 2015. Clim. Dynam., doi: 10.1007/s00382-014-2239-9 Dawson, A. and T. N. Palmer, 2015. Clim. Dynam., doi: 10.1007/s00382-014-2238-x Palmer, T.N., R. Buizza, F. Doblas-Reyes, et al., 2009, ECMWF technical memorandum 598.

  9. Forum: Communication Activism Pedagogy. Look to Our Campuses for Focus and Inspiration

    ERIC Educational Resources Information Center

    McConnell, Kathleen F.

    2017-01-01

    Lawrence R. Frey and David L. Palmer describe communication activism pedagogy (CAP) as "putting meat on critical pedagogy's theoretical bones" and applying theory to real-life activist movements (Frey & Palmer 2014). Their hope is to inspire students "beyond matriculation to develop their roles as activists," and Frey and…

  10. Road Tripping down the Digital Preservation Highway: Part IV--Classic Rides

    ERIC Educational Resources Information Center

    Colati, Jessica Branco; Colati, Gregory C.

    2011-01-01

    "Road Tripping Down the Digital Preservation Highway" follows the continuing adventures of Peter Palmer, erstwhile librarian at Bellaluna University and manager of the library's and University's digital content, as he journeys down the Digital Preservation Highway. Palmer's problem this month was somewhat more philosophical. As manager of the…

  11. Road Tripping Down the Digital Preservation Highway: Part III. Rolls Royce, Ford, or Dune Buggy?

    ERIC Educational Resources Information Center

    Colati, Jessica Branco; Colati, Gregory C.

    2011-01-01

    "Road Tripping Down the Digital Preservation Highway" follows the continuing adventures of Peter Palmer, erstwhile librarian at Bellaluna University and manager of the library's and University's digital content, as he journeys down the Digital Preservation Highway. In this article, Palmer is put in charge of a task force to determine…

  12. "The Music, Movement, and Learning Connection": A Review

    ERIC Educational Resources Information Center

    Blasi, MaryJane; Foley, Mary B.

    2006-01-01

    In this article, the authors review "The Music, Movement, and Learning Connection," written by early childhood educator and musician Hap Palmer in the September 2001 issue of Young Children, which is of significant interest to parents and teachers. As trained musicians, the authors agree with Palmer's message about music's positive effect on…

  13. Obituary: Ronald Eugene Pitts, 1949-2008

    NASA Astrophysics Data System (ADS)

    MacConnell, D. Jack

    2009-01-01

    Ronald Pitts, systems engineer in the Commanding Branch of the Space Telescope Science Institute and long-time Computer Sciences Corporation employee, died suddenly of a stroke on 4 May 2008 at his home in Laurel, Maryland. He was a dedicated scientist-engineer, husband, father, volunteer, and cherished friend to many. Ron was born on 19 January 1949 in Tucson, Arizona, and was raised, along with his sister Suzanne, on his parents' turkey farm outside Tucson. He picked up practical knowledge from his father, Vernon, and became a competent amateur electrician and plumber, skills he kept honed and used throughout his life. His mother, Ruth (Stephens), was a nurse and taught him compassion and patience and encouraged his inquisitive mind. Ron attended public schools and enrolled at the University of Arizona, graduating with a B. S. in Astronomy in 1971. Being from a family of modest means, he put himself through school working summers and part-time at a large copper mine south of town. Ron enrolled in the graduate astronomy program at the Ohio State University [OSU] in the fall of 1971 where he was a first-year fellowship student. During his second and third years, he was the Perkins Assistant, taking spectra for the very exacting but appreciative Philip Keenan who once remarked to another faculty member that Ron was the best observer he ever had. Later, in 1980, Ron was co-author with Keenan on "Revised MK Spectral Types for G, K, and M stars" and again in 1985 in a study of supergiants in open clusters. He met his future wife, Patricia Moore, also a graduate student in the department, and they were wed in 1973. Ron was also partially supported during his early OSU years by an NSF grant to Robert Wing, writing parts of Wing's photometric reduction code and observing on the program at Kitt Peak and Flagstaff in the summer of 1974. Wing remembers him as being very competent and pleasant to work with. Ron's thesis topic was "Oscillator Strengths for Neutral Iron and

  14. Between Constructivism and Connectedness

    ERIC Educational Resources Information Center

    Gordon, Mordechai

    2008-01-01

    Parker Palmer is correct in his claims that good teaching depends more on the capacity for connectedness than on technique and that helping teacher candidates cultivate a strong sense of personal identity is crucial. However, to what extent are Palmer's claims compatible with the various constructivist models of learning that are now prevalent in…

  15. Figural properties are prioritized for search under conditions of uncertainty: Setting boundary conditions on claims that figures automatically attract attention.

    PubMed

    Peterson, Mary A; Mojica, Andrew J; Salvagio, Elizabeth; Kimchi, Ruth

    2017-01-01

    Nelson and Palmer (2007) concluded that figures/figural properties automatically attract attention, after they found that participants were faster to detect/discriminate targets appearing where a portion of a familiar object was suggested in an otherwise ambiguous display. We investigated whether these effects are truly automatic and whether they generalize to another figural property-convexity. We found that Nelson and Palmer's results do generalize to convexity, but only when participants are uncertain regarding when and where the target will appear. Dependence on uncertainty regarding target location/timing was also observed for familiarity. Thus, although we could replicate and extend Nelson and Palmer's results, our experiments showed that figures do not automatically draw attention. In addition, our research went beyond Nelson and Palmer's, in that we were able to separate figural properties from perceived figures. Because figural properties are regularities that predict where objects lie in the visual field, our results join other evidence that regularities in the environment can attract attention. More generally, our results are consistent with Bayesian theories in which priors are given more weight under conditions of uncertainty.

  16. Octane and Internal Combustion Engine Advancements from a Long(er) Term Perspective: Insights from the Co-Optima Project

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Farrell, John T

    Co-Optima research and analysis have identified fuel properties that enable advanced LD and HD engines. 95 RON will directionally improve boosted SI efficiency, but higher RON and S provide additional benefits. The optimal fuel properties for future engines are still uncertain. There are a large number of blendstocks readily derived from biomass (and petroleum) that possess beneficial properties.

  17. Rewarding Resilience

    ERIC Educational Resources Information Center

    Ruffins, Paul

    2010-01-01

    This article discusses how the Ron Brown Scholars program has helped many students of color persist and fit in at elite institutions. Established in 1996 to honor the memory of Ron Brown, the first Black Secretary of Commerce who died in a 1996 military plane crash in Croatia while on a trade mission to Europe, the program each year awards $40,000…

  18. Retracted: Aetiology and clinical profile of children with 46, XY differences of sex development at an Indian referral centre.

    PubMed

    Chauhan, V; Dada, R; Jain, V

    2017-11-01

    Retraction: 'Aetiology and clinical profile of children with 46, XY differences of sex development at an Indian referral centre' by Vasundhera Chauhan, Rima Dada, Vandana Jain The above article, published online on 8 August 2016 in Wiley Online Library (http://wileyonlinelibrary.com), has been retracted by agreement between the authors, the Journal Editors-in-Chief, Wolf-Bernhard Schill and Ralf Henkel, and Blackwell Verlag GmbH. The retraction has been agreed as the result of an unresolved dispute between the first author and a colleague research fellow due to the inclusion of data from patients who were simultaneously enrolled in two studies being conducted separately by the two parties. Reference Chauhan, V., Dada, R. and Jain, V. (2016), Aetiology and clinical profile of children with 46, XY differences of sex development at an Indian referral centre. Andrologia. doi:10.1111/and.12663. © 2016 Blackwell Verlag GmbH.

  19. The impact of Michigan's Dr Ron Davis smoke-free air law on levels of cotinine, tobacco-specific lung carcinogen and severity of self-reported respiratory symptoms among non-smoking bar employees.

    PubMed

    Wilson, Teri; Shamo, Farid; Boynton, Katherine; Kiley, Janet

    2012-11-01

    To determine the impact on bar employee's health and exposure to secondhand smoke (SHS) before and after the implementation of Michigan's Dr Ron Davis smoke-free air law that went into effect on 1 May 2010, prohibiting smoking in places of work, including bars. This study used a pre/postintervention experimental design. The setting was bars in 12 Michigan counties. Subjects were bar employees, recruited through flyers and individual discussions with local health department staff. Participants completed a screening questionnaire to determine eligibility. A total of 40 eligible employees completed a demographic survey, provided urine samples for analysis of cotinine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) and completed questionnaires on respiratory and general health status 6 weeks before and 6-10 weeks after the law went into effect. The main outcome measures were urine samples for total cotinine and total NNAL and data from a self-administered respiratory and general health status questionnaire collected during the pre-law and post-law study periods. There was a significant decrease in the mean cotinine levels from 35.9 ng/ml to a non-quantifiable value (p<0.001), and there was a significant reduction in the mean NNAL level from 0.086 pmol/ml to 0.034 pmol/ml (p<0.001) 2 months after implementation of the law. There was also a significant improvement in all six self-reported respiratory symptoms (p<0.001) and general health status (p<0.001). The reduction in the SHS biomarkers cotinine and NNAL and reported improvement in respiratory health demonstrates that the Michigan smoke-free workplace law is protecting bar employee health.

  20. Antivascular Endothelial Growth Factor Bevacizumab for Radiation Optic Neuropathy: Secondary to Plaque Radiotherapy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Finger, Paul T., E-mail: pfinger@eyecancer.com; Chin, Kimberly J.

    2012-02-01

    Purpose: To evaluate the intravitreal antivascular endothelial growth factor, bevacizumab, for treatment of radiation optic neuropathy (RON). Methods and Materials: A prospective interventional clinical case series was performed of 14 patients with RON related to plaque radiotherapy for choroidal melanoma. The RON was characterized by optic disc edema, hemorrhages, microangiopathy, and neovascularization. The entry criteria included a subjective or objective loss of vision, coupled with findings of RON. The study subjects received a minimum of two initial injections of intravitreal bevacizumab (1.25 mg in 0.05 mL) every 6-8 weeks. The primary objectives included safety and tolerability. The secondary objectives includedmore » the efficacy as measured using the Early Treatment Diabetic Retinopathy Study chart for visual acuity, fundus photography, angiography, and optical coherence tomography/scanning laser ophthalmoscopy. Results: Reductions in optic disc hemorrhage and edema were noted in all patients. The visual acuity was stable or improved in 9 (64%) of the 14 patients. Of the 5 patients who had lost vision, 2 had relatively large posterior tumors, 1 had had the vision decrease because of intraocular hemorrhage, and 1 had developed optic atrophy. The fifth patient who lost vision was noncompliant. No treatment-related ocular or systemic side effects were observed. Conclusions: Intravitreal antivascular endothelial growth factor bevacizumab was tolerated and generally associated with improved vision, reduced papillary hemorrhage, and resolution of optic disc edema. Persistent optic disc neovascularization and fluorescein angiographic leakage were invariably noted. The results of the present study support additional evaluation of antivascular endothelial growth factor medications as treatment of RON.« less

  1. Decadal changes in summertime reactive oxidized nitrogen and surface ozone over the Southeast United States

    NASA Astrophysics Data System (ADS)

    Li, Jingyi; Mao, Jingqiu; Fiore, Arlene M.; Cohen, Ronald C.; Crounse, John D.; Teng, Alex P.; Wennberg, Paul O.; Lee, Ben H.; Lopez-Hilfiker, Felipe D.; Thornton, Joel A.; Peischl, Jeff; Pollack, Ilana B.; Ryerson, Thomas B.; Veres, Patrick; Roberts, James M.; Neuman, J. Andrew; Nowak, John B.; Wolfe, Glenn M.; Hanisco, Thomas F.; Fried, Alan; Singh, Hanwant B.; Dibb, Jack; Paulot, Fabien; Horowitz, Larry W.

    2018-02-01

    Widespread efforts to abate ozone (O3) smog have significantly reduced emissions of nitrogen oxides (NOx) over the past 2 decades in the Southeast US, a place heavily influenced by both anthropogenic and biogenic emissions. How reactive nitrogen speciation responds to the reduction in NOx emissions in this region remains to be elucidated. Here we exploit aircraft measurements from ICARTT (July-August 2004), SENEX (June-July 2013), and SEAC4RS (August-September 2013) and long-term ground measurement networks alongside a global chemistry-climate model to examine decadal changes in summertime reactive oxidized nitrogen (RON) and ozone over the Southeast US. We show that our model can reproduce the mean vertical profiles of major RON species and the total (NOy) in both 2004 and 2013. Among the major RON species, nitric acid (HNO3) is dominant (˜ 42-45 %), followed by NOx (31 %), total peroxy nitrates (ΣPNs; 14 %), and total alkyl nitrates (ΣANs; 9-12 %) on a regional scale. We find that most RON species, including NOx, ΣPNs, and HNO3, decline proportionally with decreasing NOx emissions in this region, leading to a similar decline in NOy. This linear response might be in part due to the nearly constant summertime supply of biogenic VOC emissions in this region. Our model captures the observed relative change in RON and surface ozone from 2004 to 2013. Model sensitivity tests indicate that further reductions of NOx emissions will lead to a continued decline in surface ozone and less frequent high-ozone events.

  2. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Palmer, K.

    If the price of electricity falls, consumption may well rise. Will air quality suffer as a result? That`s a distinct possibility, says Karen Palmer, a fellow at Resources for the Future in Washington, D.C. In the short run, companies may rely on dirtier, cheaper, coal-fired plants to respond to increased demand, Palmer says. Eventually, though, older plants will have to be retired, and they may be replaced with more efficient, natural-gas-fired units, or even renewable solar or wind-driven plants. {open_quotes}However, absent a rapid rise in the rate of growth of electricity demand, hastened introduction of new gas-fired or renewables facilitiesmore » is unlikely,{close_quotes} Palmer says. In the meantime, voluntary and mandatory caps on emissions will not necessarily be abandoned. For example, 37 Eastern states have banded together to cap emissions of nitrogen oxides and establish an emissions-trading program. {open_quotes}In short, regulations will continue to prompt a reduction in air-pollution levels regardless of the competitive pressures experienced by utilities in this new environment,{close_quotes} Palmer says.« less

  3. Impacts of Worldview, Implicit Assumptions, Biases, and Groupthink on Israeli Operational Plans in 1973

    DTIC Science & Technology

    2013-05-23

    is called worldview. It determines how individuals interpret everything. In his book, Toward a Theory of Cultural Linguistics, Gary Palmer explains...person to person and organization to organization. Although analytical frameworks provide a common starting 2Gary B. Palmer, Toward A Theory of Cultural...this point, when overwhelmed, that planners reach out to theory and make determinations based on implicit assumptions and unconscious cognitive biases

  4. 23 CFR Appendix A to Part 658 - National Network-Federally-Designated Routes

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Anchorage AK 3 Palmer. AK 2 AK 3 Fairbanks Milepost 1412 Delta Junction. AK 3 AK 1 Palmer AK 2 Fairbanks... Harbors. US 63 I-90 Rochester US 52 Rochester. US 63 MN 58 Red Wing WI State Line. US 71 IA State Line MN... State Line Red Wing MN US 2 W. of Ashland. US 141 US 41 Abrams US 8 Pembine. US 151 IA State Line...

  5. 23 CFR Appendix A to Part 658 - National Network-Federally-Designated Routes

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Anchorage AK 3 Palmer. AK 2 AK 3 Fairbanks Milepost 1412 Delta Junction. AK 3 AK 1 Palmer AK 2 Fairbanks... Harbors. US 63 I-90 Rochester US 52 Rochester. US 63 MN 58 Red Wing WI State Line. US 71 IA State Line MN... State Line Red Wing MN US 2 W. of Ashland. US 141 US 41 Abrams US 8 Pembine. US 151 IA State Line...

  6. Calcium in the Mechanism of Ammonia-Induced Astrocyte Swelling

    PubMed Central

    Jayakumar, A.R.; Rao, K.V. Rama; Tong, X.Y; Norenberg, M.D.

    2016-01-01

    Brain edema, due largely to astrocyte swelling, is an important clinical problem in patients with acute liver failure. While mechanisms underlying astrocyte swelling in this condition are not fully understood, ammonia and associated oxidative/nitrosative stress (ONS) appear to be involved. Mechanisms responsible for the increase in reactive oxygen/nitrogen species (RONS) and their role in ammonia-induced astrocyte swelling, however, are poorly understood. Recent studies have demonstrated a transient increase in intracellular Ca2+ in cultured astrocytes exposed to ammonia. As Ca2+ is a known inducer of RONS, we investigated potential mechanisms by which Ca2+ may be responsible for the production of RONS and cell swelling in cultured astrocytes after treatment with ammonia. Exposure of cultured astrocytes to ammonia (5 mM) increased the formation of free radicals, including nitric oxide, and such increase was significantly diminished by treatment with the Ca2+ chelator BAPTA-AM. We then examined the activity of Ca2+-dependent enzymes that are known to generate RONS and found that ammonia significantly increased the activities of NADPH oxidase (NOX), constitutive nitric oxide synthase (cNOS) and phospholipase A2 (PLA2) and such increases in activity were significantly diminished by BAPTA. Pretreatment of cultures with 7-nitroindazole, apocyanin and quinacrine, respective inhibitors of cNOS, NOX and PLA2, all significantly diminished RONS production. Additionally, treatment of cultures with BAPTA or with inhibitors of cNOS, NOX and PLA2 reduced ammonia-induced astrocyte swelling. These studies suggest that the ammonia-induced rise in intracellular Ca2+ activates free radical producing enzymes that ultimately contribute to the mechanism of astrocyte swelling. PMID:19393035

  7. Comprehensive dynamic on-resistance assessments in GaN-on-Si MIS-HEMTs for power switching applications

    NASA Astrophysics Data System (ADS)

    Chou, Po-Chien; Hsieh, Ting-En; Cheng, Stone; del Alamo, Jesús A.; Chang, Edward Yi

    2018-05-01

    This study comprehensively analyzed the reliability of trapping and hot-electron effects responsible for the dynamic on-resistance (Ron) of GaN-based metal–insulator–semiconductor high electron mobility transistors. Specifically, this study performed the following analyses. First, we developed the on-the-fly Ron measurement to analyze the effects of traps during stress. With this technique, the faster one (with a pulse period of 20 ms) can characterize the degradation; the transient behavior could be monitored accurately by such short measurement pulse. Then, dynamic Ron transients were investigated under different bias conditions, including combined off state stress conditions, back-gating stress conditions, and semi-on stress conditions, in separate investigations of surface- and buffer-, and hot-electron-related trapping effects. Finally, the experiments showed that the Ron increase in semi-on state is significantly correlated with the high drain voltage and relatively high current levels (compared with the off-state current), involving the injection of greater amount of hot electrons from the channel into the AlGaN/insulator interface and the GaN buffer. These findings provide a path for device engineering to clarify the possible origins for electron traps and to accelerate the development of emerging GaN technologies.

  8. Radial optic neurotomy for ischaemic central vein occlusion

    PubMed Central

    Martínez-Jardón, C S; Meza-de Regil, A; Dalma-Weiszhausz, J; Leizaola-Fernández, C; Morales-Cantón, V; Guerrero-Naranjo, J L; Quiroz-Mercado, H

    2005-01-01

    Background/aims: Ischaemic central retinal vein occlusion (CRVO) accounts for 20–50% of all CRVO. No treatment has been proved to be effective. The efficacy of radial optic neurotomy (RON) was evaluated in eyes with ischaemic CRVO. Methods: 10 patients with ischaemic CRVO underwent RON. After pars plana vitrectomy, a microvitreoretinal blade was used to incise the scleral ring, cribriform plate, and adjacent sclera at the nasal edge of the optic disc. Best corrected visual acuity (BCVA), intraocular pressure (IOP), fluorescein angiography (FA), multifocal electroretinography (mfERG), and optical coherence tomography (OCT) were measured preoperatively and at 1, 3, and 6 months postoperatively. Results: No visual improvement was noted in the eyes that underwent RON. FA and mfERG showed no increase in retinal perfusion or retinal function postoperatively. Mean macular central thickness changed from 841 (SD 170) μm preoperatively to 162 (SD 34) μm at the sixth postoperative month. One patient had retinal central artery perforation intraoperatively. One patient developed neovascular glaucoma. Conclusion: RON in ischaemic CRVO did not improve visual function (by mfERG) or visual acuity although macular thickness did improve. This technique may be associated with potential risks. Randomised studies are needed to corroborate these results. PMID:15834084

  9. Ron in Breast Development and Cancer

    DTIC Science & Technology

    2004-10-01

    4242-4246. 22. Granovsky , M., Fata, J., Pawling, J., Muller, W.J., Khokha, R., and Dennis, J.W. 2000. Suppression of tumor growth and metastasis in...of print]. 1998;18:2344-59. 41. Granovsky M. Fataj. Pawling J, Muller WJ, Khokha R, 33. Weidner N, Semple JR Welch WR, Folkman J. 37. Danilkovitch A

  10. Ron in Breast Development and Cancer

    DTIC Science & Technology

    2005-10-01

    allele restricts development of mammary tumors in transgenic mice. Cancer Res 59:4242-4246. 7. Granovsky , M., Fata, J., Pawling, J., Muller, W.J., Khokha...ahead of print]. 1998;18:2344-59. 41. Granovsky M, FataJ, Pawling J, Muller WJ, Khokha R, 33. Weidner N, Semple JR Welch WR, Folkman J. 37. Danilkovitch

  11. Evaluating Air Force Civil Engineer’s Current Automated Information Systems

    DTIC Science & Technology

    2002-03-26

    started with identifying specific processes that needed to be accomplished. These processes were flowcharted and relationships were developed (31:1...Roofs) - Critical 1. Process not defined well enough per Ron Stoner to rework a. WPAFB to flowchart and decipher ACES process for SSG/AFCESA b...Ron Stoner to rework a. WPAFB to flowchart and decipher ACES process for SSG/AFCESA b. Investigate usage of ACES as is and define Needs 2. EEIC

  12. The Fountain Head Chiropractic Hospital: the dream that almost came true

    PubMed Central

    Bakkum, Barclay W.; Nolan, Delores Bakkum

    2010-01-01

    Objective The purpose of this article is to relate information about the life of Dr William Ivens and describe the worldwide effort led by him to establish a chiropractic hospital at the Palmer School of Chiropractic. Discussion Dr William Ivens, a colorful politician and chiropractor from Winnipeg, Canada, was the driving force behind the idea of establishing a chiropractic hospital at the Palmer School of Chiropractic in Davenport, IA, during the late 1930s. With the blessings of Dr BJ Palmer, president of the Palmer School of Chiropractic, Dr Ivens led an aggressive, worldwide campaign to raise the funds necessary to establish what was to be called the Fountain Head Chiropractic Hospital. During the tumultuous years of 1937-1942, this campaign successfully raised the target sum of $50 000, thought necessary to create the hospital, but the idea never became a reality. These funds were eventually used to purchase the Clear View Sanitarium, a chiropractic psychiatric facility, in Davenport, IA, in 1952. Conclusion Dr William Ivens stands as a prime example of a relatively small, but dedicated, number of chiropractors during the mid-20th century who not only believed in, but toiled for, the idea of chiropractic care being given in an in-patient setting. PMID:22693476

  13. The in Vitro Antigenicity of Plasmodium vivax Rhoptry Neck Protein 2 (PvRON2) B- and T-Epitopes Selected by HLA-DRB1 Binding Profile

    PubMed Central

    López, Carolina; Yepes-Pérez, Yoelis; Díaz-Arévalo, Diana; Patarroyo, Manuel E.; Patarroyo, Manuel A.

    2018-01-01

    Malaria caused by Plasmodium vivax is a neglected disease which is responsible for the highest morbidity in both Americas and Asia. Despite continuous public health efforts to prevent malarial infection, an effective antimalarial vaccine is still urgently needed. P. vivax vaccine development involves analyzing naturally-infected patients' immune response to the specific proteins involved in red blood cell invasion. The P. vivax rhoptry neck protein 2 (PvRON2) is a highly conserved protein which is expressed in late schizont rhoptries; it interacts directly with AMA-1 and might be involved in moving-junction formation. Bioinformatics approaches were used here to select B- and T-cell epitopes. Eleven high-affinity binding peptides were selected using the NetMHCIIpan-3.0 in silico prediction tool; their in vitro binding to HLA-DRB1*0401, HLA-DRB1*0701, HLA-DRB1*1101 or HLA-DRB1*1302 was experimentally assessed. Four peptides (39152 (HLA-DRB1*04 and 11), 39047 (HLA-DRB1*07), 39154 (HLADRB1*13) and universal peptide 39153) evoked a naturally-acquired T-cell immune response in P. vivax-exposed individuals from two endemic areas in Colombia. All four peptides had an SI greater than 2 in proliferation assays; however, only peptides 39154 and 39153 had significant differences compared to the control group. Peptide 39047 was able to significantly stimulate TNF and IL-10 production while 39154 stimulated TNF production. Allele-specific peptides (but not the universal one) were able to stimulate IL-6 production; however, none induced IFN-γ production. The Bepipred 1.0 tool was used for selecting four B-cell epitopes in silico regarding humoral response. Peptide 39041 was the only one recognized by P. vivax-exposed individuals' sera and had significant differences concerning IgG subclasses; an IgG2 > IgG4 profile was observed for this peptide, agreeing with a protection-inducing role against P. falciparum and P. vivax as previously described for antigens such as RESA and MSP2

  14. Stueckelberg and Molecular Physics

    NASA Astrophysics Data System (ADS)

    Lacki, Jan

    The first period of E. C. G. Stueckelberg's scientific career was marked by important contributions he made to molecular physics.1 After publishing his thesis in 1927 in Basel [1] Stueckelberg joined the prestigious Palmer Physical Laboratory in Princeton where he worked under the guidance of Karl Taylor Compton, brother of Arthur Holly Compton. Stueckelberg owed this position devoted several papers to problems of molecular physics. Stueckelberg had the benefit at Princeton of exchanges with other gifted members of the Palmer Physical Laboratory, Philip M. Morse and E. U. Condon among others.3 to a recommendation by A. Sommerfeld.2 In this stimulating environment, he devoted several papers to problems of molecular physics. Stueckelberg had the benefit at Princeton of exchanges with other gifted members of the Palmer Physical Laboratory, Philip M. Morse and E. U. Condon among others.3

  15. Turbulent Reacting Flows and Supersonic Combustion

    DTIC Science & Technology

    1992-03-15

    velocity measurements. This project, as well as the MOC code described in Sec. 4.2.1, represents the Ph.D thesis research of Jennifer Palmer. 4.2.3 PLIF...growing 2-D modes and growing 45 degree modes generates streamwise modes ( Craik -type resonances). * The transition is similar to what is observed for...Mechanical Engineering Jennifer Palmer Graduate Research Assistant, Mechanical Engineering 8.0 Ph.D. DEGREES AWARDED Noel Clemens, June 1991, "An Experimental

  16. Methods for Identifying Object Class, Type, and Orientation in the Presence of Uncertainty

    DTIC Science & Technology

    1990-08-01

    on Range Finding Techniques for Computer Vision," IEEE Trans. on Pattern Analysis and Machine Intellegence PAMI-5 (2), pp 129-139 March 1983. 15. Yang... Artificial Intelligence Applications, pp 199-205, December 1984. 16. Flynn, P.J. and Jain, A.K.," On Reliable Curvature Estimation, " Proceedings of the

  17. An evaporative and engine-cycle model for fuel octane sensitivity prediction

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Moran, D.P.; Taylor, A.B.

    The Motor Octane Number (MON) ranks fuels by their chemical resistance to knock. Evaporative cooling coupled with fuel chemistry determine Research Octane Number (RON) antiknock ratings. It is shown in this study that fuel Octane sensitivity (numerically RON minus MON) is liked to an important difference between the two test methods; the RON test allows each fuel`s evaporative cooling characteristics to affect gas temperature, while the MON test generally eliminates this effect by pre-evaporation. In order to establish RON test charge temperatures, a computer model of fuel evaporation was adapted to Octane Engine conditions, and simulations were compared with realmore » Octane Test Engine measurements including droplet and gas temperatures. A novel gas temperature probe yielded data that corresponded well with model predictions. Tests spanned single component fuels and blends of isomers, n-paraffins, aromatics and alcohols. Commercially available automotive and aviation gasolines were also tested. A good correlation was observed between the computer predictions and measured temperature data across the range of pure fuels and blends. A numerical method to estimate the effect of precombustion temperature differences on Octane sensitivity was developed and applied to analyze these data, and was found to predict the widely disparate sensitivities of the tested fuels with accuracy. Data are presented showing mixture temperature histories of various tested fuels, and consequent sensitivity predictions. It is concluded that a fuel`s thermal-evaporative behavior gives rise to fuel Octane sensitivity as measured by differences between the RON and MON tests. This is demonstrated by the success, over a wide range of fuels, of the sensitivity predictor method describes. Evaporative cooling, must therefore be regarded as an important parameter affecting the general road performance of automobiles.« less

  18. The Journal of the Acoustical Society of America, Volume 96, No. 4.

    DTIC Science & Technology

    1994-10-01

    Test D. R. Palmer, T . M. Georges, J.J. 2432 transmissions Wilson, L. D. Weiner, J . A. Paisley, R. Mathiesen, R. R. Pleshek, R. R. Mabe Features of the...The first very long range phase-coded trans- missions were achieved by Spiesberger 8 in 1987. Still, there HI 12: D. R. Palmer, T . M. Georges, J . J ... T . G. Birdsall, K. Metzger, M. A. Dzieciuch and J . mammals exposed to transmissions from the Heard Island Spiesberger, "Integrated autocorrelation

  19. Monosodium Luminol for Improving Brain Function in Gulf War Illness

    DTIC Science & Technology

    2015-10-01

    Jain et al., PLoS One, 7: e46340, 2012; McAvoy et al., Front Syst Neurosci , 9:120. eCollection 2015; Oomen et al., Wiley Interdiscip Rev Cogn Sci...2007; Yassa and Stark, Trends Neurosci , 34: 515-525). In this test, each rat successively explored two different sets of identical objects (object

  20. Innate intelligence: its origins and problems

    PubMed Central

    Morgan, Lon

    1998-01-01

    Animal Magnetism and Radionics were among several occult practices used during the 19th century for the treatment of disease. D.D. Palmer was exposed to these teachings and derived many of his ideas about health from the folk medicine practices of his time. As a ‘magnetic healer’ Palmer believed he was correcting an undefined fifth force in the body that is otherwise unknown to science. Palmer believed he could influence this fifth force, termed Innate Intelligence, and that it was the explanation for the presence or absence of health. Today, Innate Intelligence remains an untestable enigma that isolates chiropractic and impedes its acceptance as a legitimate health science. The concept of Innate is derived directly from the occult practices of another era. It carries a high penalty in divisiveness and lack of logical coherence. The chiropractic profession must decide whether the concept of Innate should be retained.

  1. Combined effect of protein and oxygen on reactive oxygen and nitrogen species in the plasma treatment of tissue

    NASA Astrophysics Data System (ADS)

    Gaur, Nishtha; Szili, Endre J.; Oh, Jun-Seok; Hong, Sung-Ha; Michelmore, Andrew; Graves, David B.; Hatta, Akimitsu; Short, Robert D.

    2015-09-01

    The influence of protein and molecular, ground state oxygen (O2) on the plasma generation, and transport of reactive oxygen and nitrogen species (RONS) in tissue are investigated. A tissue target, comprising a 1 mm thick gelatin film (a surrogate for real tissue), is placed on top of a 96-well plate; each well is filled with phosphate buffered saline (PBS, pH 7.4) containing one fluorescent or colorimetric reporter that is specific for one of three RONS (i.e., H2O2, NO2-, or OH•) or a broad spectrum reactive oxygen species reporter (2,7-dichlorodihydrofluorescein). A helium cold atmospheric plasma (CAP) jet contacts the top of the gelatin surface, and the concentrations of RONS generated in PBS are measured on a microplate reader. The data show that H2O2, NO2-, or OH• are generated in PBS underneath the target. Independently, measurements are made of the O2 concentration in the PBS with and without the gelatin target. Adding bovine serum albumin protein to the PBS or gelatin shows that protein either raises or inhibits RONS depending upon the O2 concentration. Our results are discussed in the context of plasma-soft tissue interactions that are important in the development of CAP technology for medicine, biology, and food manufacturing.

  2. Archived 1976-1985 JPL Aircraft SAR Data

    NASA Technical Reports Server (NTRS)

    Thompson, Thomas W.; Blom, Ronald G.

    2016-01-01

    This report describes archived data from the Jet Propulsion Laboratory (JPL) aircraft radar expeditions in the mid-1970s through the mid-1980s collected by Ron Blom, JPL Radar Geologist. The dataset was collected during Ron's career at JPL from the 1970s through 2015. Synthetic Aperture Radar (SAR) data in the 1970s and 1980s were recorded optically on long strips of film. SAR imagery was produced via an optical, holographic technique that resulted in long strips of film imagery.

  3. Tone as a health concept: An analysis.

    PubMed

    McDowall, Donald; Emmanuel, Elizabeth; Grace, Sandra; Chaseling, Marilyn

    2017-11-01

    Concept analysis. This paper is a report on the analysis of the concept of tone in chiropractic. The purpose of this paper is to clarify the concept of tone as originally understood by Daniel David Palmer from 1895 to 1914 and to monitor its evolution over time. Data was sourced from Palmer's original work, published between 1895 and 1914. A literature search from 1980 to 2016 was also performed on the online databases CINHAL, PubMed and Scopus with key terms including 'tone', 'chiropractic', 'Palmer', 'vitalism', 'health', 'homeostasis', 'holism' and 'wellness'. Finally hand-searches were conducted through chiropractic books and professional literature from 1906 to 1980 for any references to 'tone'. Rodgers' evolutionary method of analysis was used to categorise the data in relation to the surrogates, attributes, references, antecedents and consequences of tone. A total of 49 references were found: five from publications by Palmer; three from the database searches, and; the remaining 41 from professional books, trade journals and websites. There is no clear interpretation of tone in the contemporary chiropractic literature. Tone is closely aligned with functional neurology and can be understood as an interface between the metaphysical and the biomedical. Using the concept of tone as a foundation for practice could strengthen the identity of the chiropractic profession. Copyright © 2017 Elsevier Ltd. All rights reserved.

  4. Fixing the reference frame for PPMXL proper motions using extragalactic sources

    DOE PAGES

    Grabowski, Kathleen; Carlin, Jeffrey L.; Newberg, Heidi Jo; ...

    2015-05-27

    In this study, we quantify and correct systematic errors in PPMXL proper motions using extragalactic sources from the first two LAMOST data releases and the Vèron-Cetty & Vèron Catalog of Quasars. Although the majority of the sources are from the Vèron catalog, LAMOST makes important contributions in regions that are not well-sampled by previous catalogs, particularly at low Galactic latitudes and in the south Galactic cap. We show that quasars in PPMXL have measurable and significant proper motions, which reflect the systematic zero-point offsets present in the catalog. We confirm the global proper motion shifts seen by Wu et al.,more » and additionally find smaller-scale fluctuations of the QSO-derived corrections to an absolute frame. Finally, we average the proper motions of 158 106 extragalactic objects in bins of 3° × 3° and present a table of proper motion corrections.« less

  5. Obituary: Ronald A. Parise, 1951-2008

    NASA Astrophysics Data System (ADS)

    Gull, Theodore R.

    2009-01-01

    Ronald A. Parise, astronomer and astronaut, passed away at his home in Burtonsville, Maryland, in the presence of his family on 9 May 2008. He died of a brain tumor at age 56 after several years of valiant struggle. He was an inspiration to many students, ham operators, astronomers, and friends the world over. His enthusiasm for astronomy and space exploration was infectious. We, colleagues at Goddard Space Flight Center and Computer Sciences Corporation, treasured his contributions to space astronomy and human spaceflight. Ron, along with Samuel Durrance, flew as Payload Specialist on Astro-1 and Astro-2. They were selected by peers from the instrument teams of the Hopkins Ultraviolet Telescope (HUT provided by Hopkins University), the Ultraviolet Imaging Telescope (UIT, Goddard Space Flight Center) and the Wisconsin Ultraviolet Photo-Polarimetry Experiment (WUPPE, University of Wisconsin). Astro-1 flew 2-10 December 1990 on the Columbia. Astro-2 flew 2-18 March 1995. Ron carried along amateur radio equipment and operated on the air during his free time during the missions. Ron was born 24 May 1951 in Warren, Ohio, to Henry and Catherine Parise. His interests first were in amateur radio, becoming a licensed operator by age eleven. He later was attracted to both astronomy and aviation, becoming a pilot in his teens. Ron graduated from Western Reserve High School in 1969 and attended Youngstown State University where he received a bachelor of science degree in physics with minors in mathematics, astronomy. and geology. His graduate work was at University of Florida where he obtained a masters degree in 1977 and a doctorate in 1979 in astronomy. Ron joined Operations Research, Inc. upon graduation, working at Goddard Space Flight Center where he supported studies of several NASA missions. In 1980 he joined Computer Sciences Corporation supporting the International Ultraviolet Explorer [IUE], first as a data-management scientist and later as the section manager of the

  6. The new decision-making centres. An interview with L.C. Jain.

    PubMed

    Choudhury, A R

    1993-08-01

    The interview with the Indian economist and Indian Planning Commission member was directed to issues about nongovernmental organization's (NGOs) ability to function, women's representation on Panchayats, decentralized planning, social changes in Panchayati Raj Institutions, electoral issues, and local politics. With the establishment of Panchayats in every village, there will be greater demands on NGOs for resources for social and economic advancement and for creation of opportunities. About 1 million women will get elected to Panchayats and demand that government fulfill their needs. The disadvantaged who will be elected will demand development that serve the needs of the disadvantaged. There were four or five issues in decentralization: legal changes creating decentralization, dismantling of the centralized system and strategies, distribution of funds to Panchayats and development of private resources, and availability of money for hiring technical consultants by Panchayats. A hopeful sign was evidenced in the new leadership that demanded the effective functioning of primary schools and primary health centers. The bureaucracy has been oppressive, and villagers were eager to begin making decisions for themselves. Political parties at the local level were better able to get along because people demanded very practical results; gesturing about political postures became irrelevant.

  7. Shot BEE, A Test of the TEAPOT Series, 22 March 1955.

    DTIC Science & Technology

    1981-11-24

    rcra f 1 pro v ideod hv AVSW(’ t o dot eorri ftne tit, ab iIi t, o )f t igh 11t er plan 11e s to(IsIII Si’v iv ( the f h Iast forces produced hv *the...ear devices cx peeted to vie]I d h i g h rat iOS of neitt ron to ga mnm ra d ia t io-n. Thi s objective was accompl ished by exposi ng neat ron detec

  8. The Battle of Midway Including the Aleutian Phase, June 3 to June 14, 1942. Strategical and Tactical Analysis

    DTIC Science & Technology

    1948-01-01

    columns, with the light oruimer JITSU and the festroyers in a clase smi-ciroular anti-subwarine screen. In addition, there seem to have been one destroyer...about 60 miles gast of Midway Island, course about 280°, with the submarines prooseding on tve surface* STRUNP0RON 0000 Ju OR to 100 June 5th At midnight...on Dutoh Lrbor or Cold Day. *War Diary, lomlatRon 42# May 21th to Ju = 30t%, 1941. solar Diary, Commander NorthWestleaFrontier, June 1042. ***The major

  9. Expedition 28 Landing

    NASA Image and Video Library

    2011-09-15

    Expedition 28 Flight Engineer Ron Garan answers reporters questions in traditional Kazakh dress during a press conference at the Karaganda airport shortly after he and Expedition 28 Commander Andrey Borisenko and Flight Engineer Ron Garan landed in their Soyuz TMA-21 outside of the town of Zhezkazgan, Kazakhstan, on Friday, Sept. 16, 2011. Garan, Borisenko and Samokutyaev are returning from more than five months onboard the International Space Station where they served as members of the Expedition 27 and 28 crews. Photo Credit: (NASA/Bill Ingalls)

  10. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Manjunath, Naren; Samajdar, Rhine; Jain, Sudhir R., E-mail: srjain@barc.gov.in

    Recently, the nodal domain counts of planar, integrable billiards with Dirichlet boundary conditions were shown to satisfy certain difference equations in Samajdar and Jain (2014). The exact solutions of these equations give the number of domains explicitly. For complete generality, we demonstrate this novel formulation for three additional separable systems and thus extend the statement to all integrable billiards.

  11. High-Performance Solid-State and Fiber Lasers Controlled by Volume Bragg Gratings

    DTIC Science & Technology

    2013-09-01

    Glebov: Proc. SPIE 8237 (2012) 823705. 12) I. Divliansky, D. Ott, B. Anderson, G. Venus, and L. Glebov: To be published in Opt. Express. 13) A. Jain...B. Anderson, D. Drachenberg, V. Rotar, G. Venus, and L. Glebov: Proc. SPIE 8237 (2012) 823705. 47) B. Anderson, S. Kaim, G. B. Venus, J. Lumeau, V

  12. Myles A. Steiner | NREL

    Science.gov Websites

    ; Emmett E. Perl, John Simon, Daniel J. Friedman, Nikhil Jain, Paul Sharps, Claiborne McPheeters, Yukun Sun , Kevin L. Schulte, Ryan M. France, William E. McMahon, Emmett E. Perl, Daniel J. Friedman, Journal of ; E.E. Perl, D. Kuciauskas, J. Simon, D.J. Friedman, M.A. Steiner, Journal of Applied Physics, 122

  13. Fingerprint Recognition

    DTIC Science & Technology

    2006-06-01

    RECOGNITION by Graig T. Diefenderfer June 2006 Thesis Advisor: Monique P. Fargues Second Reader: Roberto Cristi...Approved by: Monique P. Fargues Thesis Advisor Roberto Cristi Second Reader Jeffrey B. Knorr Chairman, Department of Electrical and...matching for low- quality fingerprints. Proceedings of IEEE International Conference on Image Processing, 2, 33- 36. Jain, A., Hong. L., & Bolle

  14. Target Recognition in Ultra-Wideband SAR Imagery

    DTIC Science & Technology

    1994-08-01

    Poles in a Transfer Function for Real Frequency Informa- tion," Lawrence Livermore Laboratory, UCRL -52050 (April 1974). 24. V. K Jain, T. K. Sarker, and...0.777 Gaussian 0.849 1 5,265 0.978 93 Distribution Adrnnstr ARPAJASTO Defris Techi Info Ctr Attn T DePersia Attn DTIC-DDA (2 copies) 3701 N Fairfax Dr

  15. Tissue culture of woody plants and its relevance to molecular biology

    Treesearch

    R. Minocha; S.M. Jain

    2000-01-01

    The ever increasing demand for forest products and the progressive deterioration of natural forests means that the forest industry cannot continue to rely on the exploitation of natural forests ( Jain, 1997; Tzfira et al., 1998). To meet the increasing demand for forest products while more forest land is needed for non-timber uses, the replacement of natural...

  16. eNOS uncoupling in cardiovascular diseases--the role of oxidative stress and inflammation.

    PubMed

    Karbach, Susanne; Wenzel, Philip; Waisman, Ari; Munzel, Thomas; Daiber, Andreas

    2014-01-01

    Many cardiovascular diseases and drug-induced complications are associated with - or even based on - an imbalance between the formation of reactive oxygen and nitrogen species (RONS) and antioxidant enzymes catalyzing the break-down of these harmful oxidants. According to the "kindling radical" hypothesis, the formation of RONS may trigger in certain conditions the activation of additional sources of RONS. According to recent reports, vascular dysfunction in general and cardiovascular complications such as hypertension, atherosclerosis and coronary artery diseases may be connected to inflammatory processes. The present review is focusing on the uncoupling of endothelial nitric oxide synthase (eNOS) by different mechanisms involving so-called "redox switches". The oxidative depletion of tetrahydrobiopterin (BH4), oxidative disruption of the dimeric eNOS complex, S-glutathionylation and adverse phosphorylation as well as RONS-triggered increases in levels of asymmetric dimethylarginine (ADMA) will be discussed. But also new concepts of eNOS uncoupling and state of the art detection of this process will be described. Another part of this review article will address pharmaceutical interventions preventing or reversing eNOS uncoupling and thereby normalize vascular function in a given disease setting. We finally turn our attention to the inflammatory mechanisms that are also involved in the development of endothelial dysfunction and cardiovascular disease. Inflammatory cell and cytokine profiles as well as their interactions, which are among the kindling mechanisms for the development of vascular dysfunction will be discussed on the basis of the current literature.

  17. An L-shaped low on-resistance current path SOI LDMOS with dielectric field enhancement

    NASA Astrophysics Data System (ADS)

    Ye, Fan; Xiaorong, Luo; Kun, Zhou; Yuanhang, Fan; Yongheng, Jiang; Qi, Wang; Pei, Wang; Yinchun, Luo; Bo, Zhang

    2014-03-01

    A low specific on-resistance (Ron,sp) SOI NBL TLDMOS (silicon-on-insulator trench LDMOS with an N buried layer) is proposed. It has three features: a thin N buried layer (NBL) on the interface of the SOI layer/buried oxide (BOX) layer, an oxide trench in the drift region, and a trench gate extended to the BOX layer. First, on the on-state, the electron accumulation layer forms beside the extended trench gate; the accumulation layer and the highly doping NBL constitute an L-shaped low-resistance conduction path, which sharply decreases the Ron,sp. Second, in the y-direction, the BOX's electric field (E-field) strength is increased to 154 V/μm from 48 V/μm of the SOI Trench Gate LDMOS (SOI TG LDMOS) owing to the high doping NBL. Third, the oxide trench increases the lateral E-field strength due to the lower permittivity of oxide than that of Si and strengthens the multiple-directional depletion effect. Fourth, the oxide trench folds the drift region along the y-direction and thus reduces the cell pitch. Therefore, the SOI NBL TLDMOS structure not only increases the breakdown voltage (BV), but also reduces the cell pitch and Ron,sp. Compared with the TG LDMOS, the NBL TLDMOS improves the BV by 105% at the same cell pitch of 6 μm, and decreases the Ron,sp by 80% at the same BV.

  18. A uniform doping ultra-thin SOI LDMOS with accumulation-mode extended gate and back-side etching technology

    NASA Astrophysics Data System (ADS)

    Yan-Hui, Zhang; Jie, Wei; Chao, Yin; Qiao, Tan; Jian-Ping, Liu; Peng-Cheng, Li; Xiao-Rong, Luo

    2016-02-01

    A uniform doping ultra-thin silicon-on-insulator (SOI) lateral-double-diffused metal-oxide-semiconductor (LDMOS) with low specific on-resistance (Ron,sp) and high breakdown voltage (BV) is proposed and its mechanism is investigated. The proposed LDMOS features an accumulation-mode extended gate (AG) and back-side etching (BE). The extended gate consists of a P- region and two diodes in series. In the on-state with VGD > 0, an electron accumulation layer is formed along the drift region surface under the AG. It provides an ultra-low resistance current path along the whole drift region surface and thus the novel device obtains a low temperature distribution. The Ron,sp is nearly independent of the doping concentration of the drift region. In the off-state, the AG not only modulates the surface electric field distribution and improves the BV, but also brings in a charge compensation effect to further reduce the Ron,sp. Moreover, the BE avoids vertical premature breakdown to obtain high BV and allows a uniform doping in the drift region, which avoids the variable lateral doping (VLD) and the “hot-spot” caused by the VLD. Compared with the VLD SOI LDMOS, the proposed device simultaneously reduces the Ron,sp by 70.2% and increases the BV from 776 V to 818 V. Project supported by the National Natural Science Foundation of China (Grant Nos. 61176069 and 61376079).

  19. Assessment of Drought Scenario in Western Nepal

    NASA Astrophysics Data System (ADS)

    Pandey, V. P.; Khatiwada, K. R.

    2017-12-01

    Drought is a frequent phenomenon in relatively drier western Nepal. Lack of hydro-climatic information with wider spatial coverage is hindering effective assessment of the drought events. Furthermore, drought assessment is not getting adequate attention in Nepal. This study aims to develop drought scenario for Western Nepal by evaluating various types of drought indices in Karnali River Basin (area = 4,6150 km2) and recommend the most suited set of indices for data-poor regions. On the climatic data at ten stations, drought indices were calculated from following seven selected indices: Standardized Precipitation Index (SPI), Standardized Precipitation Evapotranspiration Index (SPEI), Palmer Drought Severity Index (PDSI), (self-calibrating) Palmer Drought Severity Index (scPDSI), Reconnaissance Drought Index (RDI), Standardized Streamflow Index (SSFI), and Palmer Hydrological Drought Index (PHDI). Initial results reflect that the basin is affected by severe meteorological drought. Most of the indices show the extreme dryness scenario during the years 1984-85, 1992-93, 1995, 2000, 20002, 2008-09, and 2012. The results from the stations with long-term temperature and precipitation data sets showed a higher (up to 0.9) correlation between SPI and RDI than for SPEI and other Palmer Drought Indices, which ranged from 0.6 to 0.8 only. This suggests ability of SPI to represent magnitude and duration of the drought events fairly well in the study basin, and therefore, has potential to represent drought dynamics in data-poor regions. Keywords: Drought; Karnali River Basin; Nepal Himalaya

  20. Research in Laser Processes

    DTIC Science & Technology

    1981-01-15

    Jpn. 20, 357 (1966); C. H. Jackman , R. H. Garvey, and A. E. S. Green, J. Geophys. Res. 82, 5081 (1977). ’D. C. Cartwright, S. Trajmar, A. Chutjian...Appl Phys. 47. 3088 (1976) A .1 Palmer. I D Hess, Semiannual Rpt. # I, 2 (1975) #3 (1976) Hughes Res. lab., Malibu, Calif. ViPalmer. I D Hess...Semiannual Rpl Hughes Res. Lab,, Malibu. Call! #1, 2(1975) #3 (1976) 5.11 I. A.Schhe .1 Appl Phys. 47, I W7 (1976) 5.12 RShuker. L,Morgan, Ä

  1. Bayesian Regularization for Normal Mixture Estimation and Model-Based Clustering

    DTIC Science & Technology

    2005-08-04

    describe a four-band magnetic resonance image (MRI) consisting of 23,712 pixels of a brain with a tumor 2. Because of the size of the dataset, it is not...the Royal Statistical Society, Series B 56, 363–375. Figueiredo, M. A. T. and A. K. Jain (2002). Unsupervised learning of finite mixture models. IEEE...20 5.4 Brain MRI

  2. Investigation of the rates of surface and bulk ROS-generating reactions using indigo dye as an indicator

    NASA Astrophysics Data System (ADS)

    Anderson, Carly; Clark, Douglas; Graves, David

    2014-10-01

    We present evidence for the existence of two distinct processes that contribute to the generation of reactive oxygen and nitrogen species (RONS) in liquids exposed to cold atmospheric plasma (CAP) in air. At the plasma-liquid interface, there exists a fast surface reaction zone where RONS from the gas phase interact with species in the liquid. RONS can also be produced by ``slow'' chemical reactions in the bulk liquid, even long after plasma exposure. To separate the effects of these processes, we used indigo dye as an indicator of ROS production; specifically generation of hydroxyl radical. The rate of indigo decolorization while in direct contact with CAP is compared with the expected rate of hydroxyl radical generation at the liquid surface. When added to aqueous solutions after CAP exposure, indigo dye reacts on a time scale consistent with the production of peroxynitrous acid, ONOOH, which is known to decompose to hydroxyl radical below a pH of 6.8. In this study, the CAP used was a air corona discharge plasma run in a positive streamer mode.

  3. Identity, causality, and pronoun ambiguity.

    PubMed

    Sagi, Eyal; Rips, Lance J

    2014-10-01

    This article looks at the way people determine the antecedent of a pronoun in sentence pairs, such as: Albert invited Ron to dinner. He spent hours cleaning the house. The experiment reported here is motivated by the idea that such judgments depend on reasoning about identity (e.g., the identity of the he who cleaned the house). Because the identity of an individual over time depends on the causal-historical path connecting the stages of the individual, the correct antecedent will also depend on causal connections. The experiment varied how likely it is that the event of the first sentence (e.g., the invitation) would cause the event of the second (the house cleaning) for each of the two individuals (the likelihood that if Albert invited Ron to dinner, this would cause Albert to clean the house, versus cause Ron to clean the house). Decisions about the antecedent followed causal likelihood. A mathematical model of causal identity accounted for most of the key aspects of the data from the individual sentence pairs. Copyright © 2014 Cognitive Science Society, Inc.

  4. Effects of PTCs on nonsense-mediated mRNA decay are dependent on PTC location.

    PubMed

    Moon, Heegyum; Zheng, Xuexiu; Loh, Tiing Jen; Jang, Ha Na; Liu, Yongchao; Jung, Da-Woon; Williams, Darren R; Shen, Haihong

    2017-03-01

    The récepteur d'origine nantais (RON) gene is a proto-oncogene that is responsible for encoding the human macrophage-stimulating protein (MSP) 1 receptor. MSP activation induces RON-mediated cell dissociation, migration and matrix invasion. Isoforms of RON that exclude exons 5 and 6 encode the RONΔ160 protein, which promotes cell transformation in vitro and tumor metastasis in vivo . Premature termination codons (PTCs) in exons activate the nonsense-mediated mRNA decay (NMD) signaling pathway. The present study demonstrated that PTCs at various locations in the alternative exons 5 and 6 could induce NMD of the majority of the spliced, or partially spliced, isoforms. However, the isoforms that excluded exon 6 or exons 5 and 6 were markedly increased when produced from mutated minigenes with inserted PTCs. Furthermore, the unspliced isoform of intron 5 was not observed to be decreased by the presence of PTCs. Notably, these effects may be dependent on the location of the PTCs. The current study demonstrated a novel mechanism underlying the regulation of NMD in alternative splicing.

  5. A breakdown enhanced AlGaN/GaN MISFET with source-connected P-buried layer

    NASA Astrophysics Data System (ADS)

    Luo, Xin; Wang, Ying; Cao, Fei; Yu, Cheng-Hao; Fei, Xin-Xing

    2017-12-01

    This paper presents a breakdown-enhanced AlGaN/GaN MISFET with a source-connected P-buried layer combined with field plates (SC-PBL FPs MISFET). A TCAD tool was used to analyze the breakdown characteristics of the proposed structure, and results show that in comparison to the conventional gate field plate MISFET (GFP-C MISFET), the proposed structure provides a significant increase of breakdown voltage (VBK) due to redistribution of electric field in the gate-drain region induced by the SC-PBL and the FPs. The optimized SC-PBL FPs MISFET with a gate-drain spacing of 6 μm achieved a high Baliga's figure of merit of 2.6 GW cm-2 with a corresponding breakdown voltage (VBK) of 1311.62 V and specific on resistance (RON,sp) of 0.66 mΩ cm2, which demonstrates a good trade-off between RON,sp and VBK compared to the GFP-C MISFET with VBK of 524.27 V and RON,sp of 0.61 mΩ cm2.

  6. RF performance of GaAs pHEMT switches with various upper/lower δ-doped ratio designs

    NASA Astrophysics Data System (ADS)

    Chiu, Hsien-Chin; Fu, Jeffrey S.; Chen, Chung-Wen

    2009-02-01

    AlGaAs/InGaAs pseudomorphic high-electron-mobility transistor (pHEMT) single-pole-single-throw (SPST) switches with various upper/lower δ-doped ratio designs were fabricated and investigated for the first time. Both off-state capacitance and the specific on-resistance ( Ron) of pHEMT are dominated factors and showed characteristics of sensitive to upper/lower δ-doped ratio for RF switch applications. By adopting the series-shunt architecture, upper/lower ratio of 3:1 switch achieved the lowest insertion loss compared to 4:1 design owing to the device shunt to ground (M2) of 4:1 design exhibited a worse fundamental signal isolation especially at high power level. As to the isolation under same architecture, however, due to the lowest Ron can be obtained, the 4:1 design provided better isolation performance. In addition, the M2 also dominated the second and third harmonics suppression and meanwhile, the lowest Ron of 4:1 design was found to be beneficial to the reduction of the harmonics power transmitted to the output terminal.

  7. Performance Investigation of FSO-OFDM Communication Systems under the Heavy Rain Weather

    NASA Astrophysics Data System (ADS)

    Rashidi, Florence; He, Jing; Chen, Lin

    2017-12-01

    The challenge in the free-space optical (FSO) communication is the propagation of optical signal through different atmospheric conditions such as rain, snow and fog. In this paper, an orthogonal frequency-division multiplexing technique (OFDM) is proposed in the FSO communication system. Meanwhile, considering the rain attenuation models based on Marshal & Palmer and Carbonneau models, the performance of FSO communication system based on the OFDM is evaluated under the heavy-rain condition in Changsha, China. The simulation results show that, under a heavy-rainfall condition of 106.18 mm/h, with an attenuation factor of 7 dB/km based on the Marshal & Palmer model, the bit rate of 2.5 and 4.0 Gbps data can be transmitted over the FSO channels of 1.6 and 1.3 km, respectively, and the bit error rate of less than 1E - 4 can be achieved. In addition, the effect on rain attenuation over the FSO communication system based on the Marshal & Palmer model is less than that of the Carbonneau model.

  8. Bilateral retrobulbar optic neuropathy as the only sign of zoledronic acid toxicity.

    PubMed

    Lavado, Félix Manco; Prieto, Marta Para; Osorio, María Rosalba Ramoa; Gálvez, María Isabel López; Leal, Lucía Manzanas

    2017-10-01

    Bisphosphonates may rarely cause ocular adverse effects and retrobulbar optic neuropathy (RON) secondary to zoledronic acid is very rare. A 67-year-old man was referred because of progressive and painless decrease vision in the left eye. He had been treated with 7 cycles of zoledronic acid infusions because of metastatic prostate cancer. On examination, VA was 20/20 in the right eye (OD) and 20/50 in the left eye (OS). The optic nerve was unremarkable OU. Pattern visual evoked potentials (pVEP) and electroretinography were performed with the result of VEP responses abolished in OS, and the VEP waveform within the normal range amplitude and delayed peak latencies in OD. Due to the high suspicion of bilateral RON secondary to zoledronic acid, we decided to discontinue the treatment. Two months later, VA was 20/20 OD and hand motions OS, with relative afferent pupillary defect and a pallor of the optic disc in OS. The diagnosis of bilateral RON secondary to zoledronic acid infusions was confirmed, and it was only partially reversible. Zoledronic acid is a potent new generation bisphosphonate increasingly used in oncologic patients and it is usually well tolerated. Optic nerve toxicity is not a side effect recognised by either the Food and Drug Administration or the drug manufacturers, and to our knowledge, this is the first case of zoledronic acid-related bilateral RON with late onset. In conclusion, patients treated with bisphosphonates should be informed about the possibility of ocular side-effects, and ophthalmologists should be consider discontinuing the drug. Copyright © 2017 Elsevier Ltd. All rights reserved.

  9. Hayes Receives 2012 Ronald Greeley Early Career Award in Planetary Science: Response

    NASA Astrophysics Data System (ADS)

    Hayes, Alexander G.

    2013-10-01

    I am deeply honored to be the inaugural recipient of the Ronald Greeley Early Career Award. Ron was an icon in the field of planetary science, and the establishment of this award is a fitting way to pay tribute to his legacy. I applaud Laurie Leshin, Bill McKinnon, and the rest of the AGU Planetary Science section officers and selection committee for taking the time to organize this memorial. Ron is remembered not only for his fundamental scientific contributions but also for his mentorship and support of early-career scientists, both his own students and postdocs and those of his colleagues.

  10. Combustion characteristics of various fuels during research octane number testing on an instrumented CFR F1/F2 engine

    DOE PAGES

    Kolodziej, Christopher P.; Wallner, Thomas

    2017-04-01

    The Cooperative Fuels Research (CFR) engine is the long-established standard for characterization of fuel knock resistance in spark-ignition internal combustion engines. Despite its measurements of RON and MON being widely used, there is little understanding of what governs the CFR octane rating for fuels of various chemical compositions compared to primary reference fuels (iso-octane and n-heptane). Some detailed combustion characteristics were measured on a highly instrumented CFR F1/F2 engine during RON testing of fuels with significantly different chemical composition. Our results revealed differences in the cylinder pressure and temperature conditions, as well as knocking characteristics.

  11. Combustion characteristics of various fuels during research octane number testing on an instrumented CFR F1/F2 engine

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kolodziej, Christopher P.; Wallner, Thomas

    The Cooperative Fuels Research (CFR) engine is the long-established standard for characterization of fuel knock resistance in spark-ignition internal combustion engines. Despite its measurements of RON and MON being widely used, there is little understanding of what governs the CFR octane rating for fuels of various chemical compositions compared to primary reference fuels (iso-octane and n-heptane). Some detailed combustion characteristics were measured on a highly instrumented CFR F1/F2 engine during RON testing of fuels with significantly different chemical composition. Our results revealed differences in the cylinder pressure and temperature conditions, as well as knocking characteristics.

  12. Life on the edge in eastern Alaska: Basal Ordovician(Tremadocian), platform-margin faunas of the Jones Ridge Formation

    USGS Publications Warehouse

    Taylor, J. F.; Allen, T. J.; Repetski, John E.; Strauss, J. V.; Irwin, S. J.

    2015-01-01

    As the most fossiliferous and least deformed succession of unequivocally Laurentian lower Paleozoic strata in Alaska, the Jones Ridge Limestone has provided critical data for numerous stratigraphic studies (e. g. Palmer 1968; Harris et al. 1995; Dumoulin et al. 2002; Dumoulin and Harris 2012) focused on the Cambrian and Ordovician of northwestern North America/northeastern Laurentia (Figure 1). The Jones Ridge faunas are also significant in having provided the type material for some of the widespread and biostratigraphically useful latest Furongian and (perhaps) earliest Tremadocian species described by Kobayashi (1936) and Palmer (1968). Unfortunately, some of those taxa were based on very limited material for which, in the earlier study in particular, no detailed information regarding locality or stratigraphic horizon was provided. The limited amount of information and material available for study from Jones Ridge results largely from its remote location on the Yukon-Alaska boundary approximately 25km north of Eagle, Alaska, which renders it accessible only by helicopter. Parts of three field seasons (2010, 2011, and 2014) were invested in re-description and intensive sampling of the type section of the Jones Ridge Formation in order to produce an integrated and greatly refined set of biostratigraphic, chemostratigraphic, and sedimentological data. The new data support the interpretation offered by Palmer (1968) of the Jones Ridge strata as the product of deposition in outermost platform to upper slope environments offered by Palmer (1968) on the basis of taxonomic content of the faunas and close proximity of deep water units of equivalent age a very short distance to the southwest.

  13. Real-Time and High-Fidelity Simulation Environment for Autonomous Ground Vehicle Dynamics

    DTIC Science & Technology

    2013-08-01

    ENGINEERING AND TECHNOLOGY SYMPOSIUM (GVSETS), SET FOR AUG. 21-22, 2013 14. ABSTRACT briefing charts 15. SUBJECT TERMS 16. SECURITY CLASSIFICATION OF: 17...EDL & Aero-Flight DSENDS Airships Planetary & Terrain models SimScape Simulation framework Dshell Flex & Multibody dynamics DARTS 3D...7 DARTS Rigid/Flexible Real-Time Multibody Dynamics Engine Recipient of the NASA Software of the Year Award. Abhinandan Jain, "Robot and

  14. Metrics for Uncertainty in Organizational Decision-Making

    DTIC Science & Technology

    2006-06-01

    measurement and computational agents. Computational Economics : A Perspective from Computational Intelligence book. S.- H. Chen, Jain, Lakhmi, & Tai...change and development." Annual Review of Psychology 50: 361-386. Von Neumann, J., and Morgenstern, O. (1953). Theory of games and economic ...2006 Interviews versus Field data MI MPU Hanford/HAB (CR: cooperation) Savannah River Site/SAB (MR: competition) ER ER about 7.1% in 2002 ER

  15. Crosstalk of mitochondria with NADPH oxidase via reactive oxygen and nitrogen species signalling and its role for vascular function

    PubMed Central

    Di Lisa, Fabio; Oelze, Matthias; Kröller‐Schön, Swenja; Steven, Sebastian; Schulz, Eberhard; Münzel, Thomas

    2016-01-01

    Abstract Cardiovascular diseases are associated with and/or caused by oxidative stress. This concept has been proven by using the approach of genetic deletion of reactive species producing (pro‐oxidant) enzymes as well as by the overexpression of reactive species detoxifying (antioxidant) enzymes leading to a marked reduction of reactive oxygen and nitrogen species (RONS) and in parallel to an amelioration of the severity of diseases. Likewise, the development and progression of cardiovascular diseases is aggravated by overexpression of RONS producing enzymes as well as deletion of antioxidant RONS detoxifying enzymes. Thus, the consequences of the interaction (redox crosstalk) of superoxide/hydrogen peroxide produced by mitochondria with other ROS producing enzymes such as NADPH oxidases (Nox) are of outstanding importance and will be discussed including the consequences for endothelial nitric oxide synthase (eNOS) uncoupling as well as the redox regulation of the vascular function/tone in general (soluble guanylyl cyclase, endothelin‐1, prostanoid synthesis). Pathways and potential mechanisms leading to this crosstalk will be analysed in detail and highlighted by selected examples from the current literature including hypoxia, angiotensin II‐induced hypertension, nitrate tolerance, aging and others. The general concept of redox‐based activation of RONS sources via “kindling radicals” and enzyme‐specific “redox switches” will be discussed providing evidence that mitochondria represent key players and amplifiers of the burden of oxidative stress. Linked Articles This article is part of a themed section on Redox Biology and Oxidative Stress in Health and Disease. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v174.12/issuetoc PMID:26660451

  16. Characterization of Hydrocarbon Emissions from Gasoline Direct-Injection Compression Ignition Engine Operating on a Higher Reactivity Gasoline Fuel

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Storey, John; Lewis, Samuel; Moses-DeBusk, Melanie

    Low temperature combustion engine technologies are being investigated for high efficiency and low emissions. However, such engine technologies often produce higher engine-out hydrocarbon (HC) and carbon monoxide (CO) emissions, and their operating range is limited by the fuel properties. In this study, two different fuels, a US market gasoline containing 10% ethanol (RON 92 E10) and a higher reactivity gasoline (RON 80 E0), were compared on a Delphi’s second generation Gasoline Direct-Injection Compression Ignition (Gen 2.0 GDCI) multi-cylinder engine. The engine was evaluated at three operating points ranging from a light load condition (800 rpm/2 bar IMEP g) to mediummore » load conditions (1500 rpm/6 bar and 2000 rpm/10 bar IMEP g). The engine was equipped with two oxidation catalysts, between which was located the exhaust gas recirculation (EGR) inlet. Samples were taken at engine-out, between the catalysts, and at tailpipe locations. In addition, part of the raw exhaust was diluted and sampled for HC speciation. Canisters and sorbent membranes were used to collect volatile HCs and semi-volatile HCs, respectively. Di-nitrophenyl hydrazine (DNPH) cartridges were also used for collecting oxygenated species. Results showed overall lower HC emissions with the RON 80 E0 fuel compared to the RON 92 E10 fuel. For both fuels, the percentage of aromatic HCs was higher in the exhaust than in the fuels themselves. High engine-out aldehyde and ketone emissions were observed for both fuels. The reported HC speciation information can be useful for the development of a robust emission control system.« less

  17. High sensitive and high temporal and spatial resolved image of reactive species in atmospheric pressure surface discharge reactor by laser induced fluorescence

    NASA Astrophysics Data System (ADS)

    Gao, Liang; Feng, Chun-Lei; Wang, Zhi-Wei; Ding, Hongbin

    2017-05-01

    The current paucity of spatial and temporal characterization of reactive oxygen and nitrogen species (RONS) concentration has been a major hurdle to the advancement and clinical translation of low temperature atmospheric plasmas. In this study, an advanced laser induced fluorescence (LIF) system has been developed to be an effective antibacterial surface discharge reactor for the diagnosis of RONS, where the highest spatial and temporal resolution of the LIF system has been achieved to ˜100 μm scale and ˜20 ns scale, respectively. Measurements on an oxidative OH radical have been carried out as typical RONS for the benchmark of the whole LIF system, where absolute number density calibration has been performed on the basis of the laser Rayleigh scattering method. Requirements for pixel resolved spatial distribution and outer plasma region detection become challenging tasks due to the low RONS concentration (˜ppb level) and strong interference, especially the discharge induced emission and pulsed laser induced stray light. In order to design the highly sensitive LIF system, a self-developed fluorescence telescope, the optimization of high precision synchronization among a tunable pulsed laser, a surface discharge generator, intensified Charge Coupled Device (iCCD) camera, and an oscilloscope have been performed. Moreover, an image BOXCAR approach has been developed to remarkably improve the sensitivity of the whole LIF system by optimizing spatial and temporal gating functions via both hardware and software, which has been integrated into our automatic control and data acquisition system on the LabVIEW platform. In addition, a reciprocation averaging measurement has been applied to verify the accuracy of the whole LIF detecting system, indicating the relative standard deviation of ˜3%.

  18. Characterization of Hydrocarbon Emissions from Gasoline Direct-Injection Compression Ignition Engine Operating on a Higher Reactivity Gasoline Fuel

    DOE PAGES

    Storey, John; Lewis, Samuel; Moses-DeBusk, Melanie; ...

    2017-02-05

    Low temperature combustion engine technologies are being investigated for high efficiency and low emissions. However, such engine technologies often produce higher engine-out hydrocarbon (HC) and carbon monoxide (CO) emissions, and their operating range is limited by the fuel properties. In this study, two different fuels, a US market gasoline containing 10% ethanol (RON 92 E10) and a higher reactivity gasoline (RON 80 E0), were compared on a Delphi’s second generation Gasoline Direct-Injection Compression Ignition (Gen 2.0 GDCI) multi-cylinder engine. The engine was evaluated at three operating points ranging from a light load condition (800 rpm/2 bar IMEP g) to mediummore » load conditions (1500 rpm/6 bar and 2000 rpm/10 bar IMEP g). The engine was equipped with two oxidation catalysts, between which was located the exhaust gas recirculation (EGR) inlet. Samples were taken at engine-out, between the catalysts, and at tailpipe locations. In addition, part of the raw exhaust was diluted and sampled for HC speciation. Canisters and sorbent membranes were used to collect volatile HCs and semi-volatile HCs, respectively. Di-nitrophenyl hydrazine (DNPH) cartridges were also used for collecting oxygenated species. Results showed overall lower HC emissions with the RON 80 E0 fuel compared to the RON 92 E10 fuel. For both fuels, the percentage of aromatic HCs was higher in the exhaust than in the fuels themselves. High engine-out aldehyde and ketone emissions were observed for both fuels. The reported HC speciation information can be useful for the development of a robust emission control system.« less

  19. Variation in structure of proteins by adjusting reactive oxygen and nitrogen species generated from dielectric barrier discharge jet

    NASA Astrophysics Data System (ADS)

    Park, Ji Hoon; Kim, Minsup; Shiratani, Masaharu; Cho, Art. E.; Choi, Eun Ha; Attri, Pankaj

    2016-10-01

    Over the last few years, the variation in liquid chemistry due to the development of radicals generated by cold atmospheric plasma (CAP) has played an important role in plasma medicine. CAP direct treatment or CAP activated media treatment in cancer cells shows promising anticancer activity for both in vivo and in vitro studies. However, the anticancer activity or antimicrobial activity varies between plasma devices due to the different abilities among plasma devices to generate the reactive oxygen and nitrogen species (RONS) at different ratios and in different concentrations. While the generation of RONS depends on many factors, the feeding gas plays the most important role among the factors. Hence, in this study we used different compositions of feeding gas while fixing all other plasma characteristics. We used Ar, Ar-O2 (at different ratios), and Ar-N2 (at different ratios) as the working gases for CAP and investigated the structural changes in proteins (Hemoglobin (Hb) and Myoglobin (Mb)). We then analyzed the influence of RONS generated in liquid on the conformations of proteins. Additionally, to determine the influence of H2O2 on the Hb and Mb structures, we used molecular dynamic simulation.

  20. Mechanisms of Plasma Therapeutics

    NASA Astrophysics Data System (ADS)

    Graves, David

    2015-09-01

    In this talk, I address research directed towards biomedical applications of atmospheric pressure plasma such as sterilization, surgery, wound healing and anti-cancer therapy. The field has seen remarkable growth in the last 3-5 years, but the mechanisms responsible for the biomedical effects have remained mysterious. It is known that plasmas readily create reactive oxygen species (ROS) and reactive nitrogen species (RNS). ROS and RNS (or RONS), in addition to a suite of other radical and non-radical reactive species, are essential actors in an important sub-field of aerobic biology termed ``redox'' (or oxidation-reduction) biology. It is postulated that cold atmospheric plasma (CAP) can trigger a therapeutic shielding response in tissue in part by creating a time- and space-localized, burst-like form of oxy-nitrosative stress on near-surface exposed cells through the flux of plasma-generated RONS. RONS-exposed surface layers of cells communicate to the deeper levels of tissue via a form of the ``bystander effect,'' similar to responses to other forms of cell stress. In this proposed model of CAP therapeutics, the plasma stimulates a cellular survival mechanism through which aerobic organisms shield themselves from infection and other challenges.

  1. Ultra-low specific on-resistance 700V LDMOS with a buried super junction layer

    NASA Astrophysics Data System (ADS)

    Wang, Hai-Shi; Li, Zhi-you; Li, Ke; Qiao, Ming

    2018-01-01

    An ultra-low specific on-resistance 700 V lateral double-diffused MOSFET (LDMOS) with a buried super junction (BSJ) layer is proposed. [1-9] Buried P-pillars in the LDMOS can be depleted by neighboring N-pillars, overlying and underlying N-drift regions simultaneously, thus allowing a higher doping concentration. Consequently, the doping concentration of either the N-drift regions or N-pillars, or both, may also be increased therewith to compensate the surplus charges in the P-pillars. Compared with conventional surface super junction (SSJ) LDMOS, in which the super junction layer is implemented at the upper surface of the drift region, and P-pillars can only be depleted by the adjacent N-pillars and the N-drift regions beneath, the proposed novel LDMOS structure may have a lower specific on-resistance (Ron,sp) while maintain the same breakdown voltage (BV). Simulation results indicate that the Ron,sp of the novel structure is only 80.5 mΩ cm2 with a high BV of 750 V, which is reduced by 17% in comparison with the Ron,sp of a conventional SSJ LDMOS.

  2. Aqueous reactive species induced by a PCB surface micro-discharge air plasma device: a quantitative study

    NASA Astrophysics Data System (ADS)

    Chen, Chen; Li, Fanying; Chen, Hai-Lan; Kong, Michael G.

    2017-11-01

    This paper presents a quantitative investigation on aqueous reactive species induced by air plasma generated from a printed circuit board surface micro-discharge (SMD) device. Under the conditions amenable for proliferation of mammalian cells, concentrations of ten types of reactive oxygen and nitrogen species (RONS) in phosphate buffering solution (PBS) are measured by chemical fluorescent assays and electron spin resonance spectroscopy (ESR). Results show that concentrations of several detected RNS (NO2- , NO3- , peroxynitrites, and NO2\\centerdot ) are higher than those of ROS (H2O2, O2\\centerdot - , and 1O2) in the air plasma treated solution. Concentrations of NO3- can reach 150 times of H2O2 with 60 s plasma treatment. For short-lived species, the air plasma generates more copious peroxynitrite than other RONS including NO2\\centerdot , O2\\centerdot - , 1O2, and N{{O}\\centerdot } in PBS. In addition, the existence of reaction between H2O2 and NO2- /HNO2 to produce peroxynitrite is verified by the chemical scavenger experiments. The reaction relations between detected RONS are also discussed.

  3. Prostate Cancer Progression and Serum Sibling (Small Integrin Binding N-Linked Glycoprotein) Levels

    DTIC Science & Technology

    2008-10-01

    Alka Jain,2 Matt Tayback,2 and Neal S. Fedarko2 1Craniofacial and Skeletal Diseases Branch, National Institute of Dental and Craniofacial Research... Dental and Craniofacial Research, NIH, DHHS, Bethesda, MD, U.S.A. 2Division of Geriatrics, Department of Medicine, Johns Hopkins University, School of...hypophosphatemia [ Carey et al., 1986]. We have previously reported on a patient with LSNS and hypophosphatemia where the plasma phosphatonin, fibroblast

  4. Merging Surface Reconstructions of Terrestrial and Airborne LIDAR Range Data

    DTIC Science & Technology

    2009-05-19

    Mangan and R. Whitaker. Partitioning 3D surface meshes using watershed segmentation . IEEE Trans. on Visualization and Computer Graphics, 5(4), pp...Jain, and A. Zakhor. Data Processing Algorithms for Generating Textured 3D Building Facade Meshes from Laser Scans and Camera Images. International...acquired set of overlapping range images into a single mesh [2,9,10]. However, due to the volume of data involved in large scale urban modeling, data

  5. Joint Sparse Representation for Robust Multimodal Biometrics Recognition

    DTIC Science & Technology

    2012-01-01

    described in III. Experimental evaluations on a comprehensive multimodal dataset and a face database have been described in section V. Finally, in...WVU Multimodal Dataset The WVU multimodal dataset is a comprehensive collection of different biometric modalities such as fingerprint, iris, palmprint ...Martnez and R. Benavente, “The AR face database ,” CVC Technical Report, June 1998. [29] U. Park and A. Jain, “Face matching and retrieval using soft

  6. Improving the Selection Classification, and Utilization of Army Enlisted Personnel. Supplement

    DTIC Science & Technology

    1988-05-01

    Consumer Research, 5, 103-123. Jain, Arun K ., Acito, Franklin, Malhotra , Naresh , and Mahajan, Vijay (1978). A comparison of predictive validity of...Technical Area Lawrence M. Hanser, Chief MANPOWER AND PERSONNEL RESEARCH LABORATORY Newell K . Eaton, Director DTIC "p S "LIEC T E .,J. JUN 221988 U. S. Army...8217 , w .. CONTENTS Page ’ Utility Estimation in Five Enlisted Occupations. . . . . . . . . . . . . Newell K . Eaton, Hilda Wing, and Alan Lau (ARI

  7. Real-Time and High-Fidelity Simulation Environment for Autonomous Ground Vehicle Dynamics

    DTIC Science & Technology

    2013-08-01

    Propulsion Laboratory California Institute of Technology Paramsothy Jayakumar , Ph.D. U.S. Army TARDEC Jim Overholt, Ph.D. U.S. Air Force...NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Paramsothy Jayakumar ; Jim Overholt; Calvin Kuo; Abhi Jain; Havard Grip 5d. PROJECT...Dynamics, Cameron, et al. UNCLASSIFIED Page 10 of 11 REFERENCES [1] P. Jayakumar , W. Smith, B. A. Ross, R. Jategoankar and K. Konarzewski

  8. Redescriptions of two echinostomes from birds in Paraguay, with comments on Drepanocephalus Dietz, 1909 and Paryphostomum Dietz, 1909 (Digenea: Echinostomatidae).

    PubMed

    Kostadinova, Aneta; Vaucher, Claude; Gibson, David I

    2002-10-01

    Two species of echinostomatid trematodes from Paraguayan birds are redescribed: these are Drepanocephalus spathans Dietz, 1909 from Phalacrocorax olivaceus and Paryphostomum segregatum Dietz, 1909 from Coragyps atratus. The genera Drepanocephalus Dietz, 1909 and Paryphostomum Dietz, 1909 are redefined and the species previously assigned to them reviewed. Paryphostomum mexicanum (Lamothe-Argumedo & Pérez-Ponce de León, 1989) n. comb. and P. parvicephalum (Rietschel & Werding, 1978) n. comb. are transferred from Drepanocephalus to Paryphostomum. A key to the species of Paryphostomum is presented, and the nominal species of Echinostoma Rudolphi, 1809, Nephrostomum Dietz, 1909 and Artyfechinostomum Lane, 1915 previously ascribed to this genus are commented upon. New combinations for species previously attributed to Paryphostomum are: Echinostoma pentalobum (Verma, 1936) n. comb.; E. baiyangdienense (Ku, Pan, Chiu, Li & Chu, 1973) n. comb.; Nephrostomum dollfusi (Agarwal, 1959) n. comb.; and Artyfechinostomum neotoma (Jain, 1953) n. comb. Species attributed to Paryphostomum which are here considered species inquirendae are: Paryphostomum (Lepustomum) mehrii Jain, 1953 sp. inq.; P. fragosum (Dietz, 1909) sp. inq.; P. horai Baugh, 1950 sp. inq.; P. huaccaci Ibáñez, 1974 sp. inq.; P. agrawali Gupta & Singh, 1986 sp. inq.; P. siddiqui Gupta & Singh, 1986 sp. inq.; P. durgensis Sapre, 1969 sp. inq.; and P. globorchum Oshmarin, 1970 sp. inq.

  9. Magnetically Responsive Optical Nanoprobes (MagRONs) and Systems

    DTIC Science & Technology

    2004-02-28

    5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) 8. PERFORMING ORGANIZATION REPORT NUMBER The regents of the University of...research. MagMOON Architechtures I Controlled deposition of magnetic materials onto any nanosensor Prism coated nanoparticles Electric field sensors...into a predefined pattern has been the focus of many investigations.[7-11] For example, strawberry-like composite materials using organic -inorganic

  10. L Ron Hubbard's science fiction quest against psychiatry.

    PubMed

    Hirshbein, Laura

    2016-12-01

    Layfayette Ronald Hubbard (1911-1986) was a colourful and prolific American writer of science fiction in the 1930s and 1940s. During the time between his two decades of productivity and his return to science fiction in 1980, Hubbard founded the Church of Scientology. In addition to its controversial status as a religion and its troubling pattern of intimidation and litigation directed towards its foes, Scientology is well known as an organised opponent to psychiatry. This paper looks at Hubbard's science fiction work to help understand the evolution of Scientology's antipsychiatry stance, as well as the alternative to psychiatry offered by Hubbard. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  11. Understanding anthocyanin: Researcher and educator Dr. Ron Wrolstad

    USDA-ARS?s Scientific Manuscript database

    This invited presentation is in honor of Dr. Ronald E. Wrolstad (Distinguished Professor Emeritus), recipient of the 2017 ACS AGFD Advancement of the Application of Agricultural and Food Chemistry Award. The talk will be a brief overview of Dr. Ronald E. Wrolstad’s research program and career; Dr. W...

  12. Optical Strategies for Studying Metastatic Mechanisms, Tumor Cell Detection and Treatment of Prostate Cancer

    DTIC Science & Technology

    2006-10-01

    Treatment, Photodynamic Therapy, Biological Response 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT 18 . NUMBER OF PAGES 19a. NAME OF...photodynamic therapy in a rat prostate tumor model. Clin Cancer Res 2005;11:720-7. 18 . Fukumura D, Yuan F, Monsky WL, Chen Y, Jain RK. Effect of host...angiogenesis and microvascular functions in human breast cancer xenografts : Mammary fat pad versus cranial tumors. Clin Cancer Res 2002;8:1008-13. 20. Hasan T

  13. Studies on Decomposition and Combustion Mechanism of Solid Fuel Rich Propellants

    DTIC Science & Technology

    2010-08-30

    thrust to cruise at supersonic speed. This was followed by the test of large diameter ramjet called burner test vehicle (BTV). Advanced low volume...propellant surface. Vernekar et al (43) found that in pressed AP-Al pellets , maximum burn rate is obtained at intermediate metal content. Jain et al...conjunction with high pressure window strand burner . They found that the propellant combustion was irregular and regression rate varied from 0.3 to 3

  14. Prostate Can Men: The Effect of Body Habitus and Physical Activity

    DTIC Science & Technology

    2006-02-01

    throughout the active phase of the study and 35 men had died of prostate cancer by 1980 . An additional 88 prostate cancer deaths 7 between 1981...prostate cancer by 1980 . An additional 88 prostate cancer deaths between 1981 and 2002 were ascertained using passive follow-up by matching participants...6(4):865- 70. (3) Jain MG, Hislop GT, Howe GR, Ghadirian P. Plant foods, antioxidants, and prostate cancer risk: findings from case-control

  15. Computer Modeling of Complete IC Fabrication Process.

    DTIC Science & Technology

    1987-05-28

    James Shipley National Semi.Peter N. Manos AMD Ritu Shrivastava Cypress Semi. Corp.Deborah D. Maracas Motorola, Inc. Paramjit Singh Rockwell Intl.Sidney...Carl F Daegs Sandia Hishan Z Massoud Duke* UnIVersdy Anant Dix* Silicon Systems David Matthews Hughes Rese~arch Lab DIolidi DoIIos Spery Tmioomly K...Jaczynski AT&T Bell Labs Jack C. Carlson Motorola Sanjay Jain AT&T Bell Labs Andrew Chan Fairchild Weston Systems Werner Juengling AT&T Bell Labs

  16. Proterozoic metamorphism and uplift history of the north-central Laramie Mountains, Wyoming, USA

    USGS Publications Warehouse

    Patel, S.C.; Frost, B.R.; Chamberlain, K.R.; Snyder, G.L.

    1999-01-01

    The Laramie Mountains of south-eastern Wyoming contain two metamorphic domains that are separated by the 1.76 Ga. Laramie Peak shear zone (LPSZ). South of the LPSZ lies the Palmer Canyon block, where apatite U-Pb ages are c. 1745 Ma and the rocks have undergone Proterozoic kyanite-grade Barrovian metamorphism. In contrast, in the Laramie Peak block, north of the shear zone, the U-Pb apatite ages are 2.4-2.1 Ga, the granitic rocks are unmetamorphosed and supracrustal rocks record only low-T amphibolite facies metamorphism that is Archean in age. Peak mineral assemblages in the Palmer Canyon block include (a) quartz-biotite-plagioclase-garnet-staurolite-kyanite in the pelitic schists; (b) quartz-biotite-plagioclase-low-Ca amphiboles-kyanite in Mg-Al-rich schists, and locally (c) hornblende-plagioclase-garnet in amphibolites. All rock types show abundant textural evidence of decompression and retrograde re-equilibration. Notable among the texturally late minerals are cordierite and sapphirine, which occur in coronas around kyanite in Mg-Al-rich schists. Thermobarometry from texturally early and late assemblages for samples from different areas within the Palmer Canyon block define decompression from > 7 kbar to < 3 kbar. The high-pressure regional metamorphism is interpreted to be a response to thrusting associated with the Medicine Bow orogeny at c. 1.78-1.76 Ga. At this time, the north-central Laramie Range was tectonically thickened by as much as 12 km. This crustal thickening extended for more than 60 km north of the Cheyenne belt in southern Wyoming. Late in the orogenic cycle, rocks of the Palmer Canyon block were uplifted and unroofed as the result of transpression along the Laramie Peak shear zone to produce the widespread decompression textures. The Proterozoic tectonic history of the central Laramie Range is similar to exhumation that accompanied late-orogenic oblique convergence in many Phanerozoic orogenic belts.

  17. Incorporating motivational interviewing into rheumatology care.

    PubMed

    Palmer, Deborah; Miedany, Yasser El

    2018-04-12

    Deborah Palmer, Advanced Nurse Practitioner, North Middlesex University Hospital, and Yasser El Miedany, Consultant Rheumatologist, discuss ways to close the gap between disease control and patient empowerment.

  18. Air Quality Monitoring and Sensor Technologies

    EPA Pesticide Factsheets

    EPA scientist Ron Williams presented on the features, examination, application, examples, and data quality of continuous monitoring study designs at EPA's Community Air Monitoring Training in July 2015.

  19. 75 FR 22863 - Notice of Permit Applications Received Under the Antarctic Conservation Act of 1978 (Pub. L. 95-541)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-30

    .... Applicant: Stevem D. Emslie, Department of Biology and Marine Biology, University of North Carolina... Point, Anvers Island, Palmer Archipelago, ASPA 143-Marine Plain, Mule Peninsula, Vestfold Hills, ASPA...

  20. Acoustic Directivity Patterns for Army Weapons

    DTIC Science & Technology

    1979-01-01

    work was performed by the Environmental Division (EN), u.S. Army Construction Engineering Research Laboratory (CERL). Dr. R. K. Jain is Chief of EN...V) P.0. Schomer,,, L. M./Little I rTPRFORMING ORGANI ZATION NAME AND ADDRESS 0.PROG3RAM ELEMENT. PPOJECT, TAWF U.S. ARMY AREA & WORK UNIT NUMBERS...34Environmental Quality for Construction and Operation of Military Facilities" Task 03, "Pollution Control Technology" and Work Unit 001, "Prediction of

  1. Free Carrier Induced Spectral Shift for GaAs Filled Metallic Hole Arrays

    DTIC Science & Technology

    2012-03-13

    Bahae , G. I . Stegeman, K. Al-hemyari, J. S. Aitchison, and C. N. Ironside, “Limitation due to three-photon absorption on the useful spectral range...Free carrier induced spectral shift for GaAs filled metallic hole arrays Jingyu Zhang 1,2,* , Bin Xiang 3 , Mansoor Sheik- Bahae 4 , and S. R. J...OCIS codes: (310.6628) Subwavelength structures;(190.4350) Nonlinear optics at surfaces References and links 1. J. M. Luther, P. K. I . Jain, T. Ewers

  2. Src Kinase: A Novel Target of Early-Stage ER-Negative Breast Cancer

    DTIC Science & Technology

    2012-03-01

    patients with early stage ErbB2-overexpressing biopsies and ER- atypia . 13 REFERENCES: 1. Jordan VC. Tamoxifen for breast cancer prevention. Proc Soc...Summary01-03-2012 Src Kinase: A Novel Target of Early-Stage ER-Negative Breast Cancer Shalini Jain University of Texas M.D. Anderson Cancer Center Houston...SUBTITLE “Src Kinase: A Novel Target of Early-Stage ER-Negative Breast Cancer” 5a. CONTRACT NUMBER W81XWH-11-1-0004 5b. GRANT NUMBER

  3. Effects of Pollutants on Vertebrate Cells in Vitro.

    DTIC Science & Technology

    1981-01-01

    ex- Barkla and Tutton, 1978). More specifically, perimental setups, the cells were enzymatically re- some of these effects are produced in moved from...upon re- biological membranes (Balduini et al., 1977, exposure to fresh hydrazine, they appeared Barkla and Tutton, 1977; Braun and Wolfe, to attain a...Schneideberg’s Phartna- Chient. 358. 1143-1148. col. 298, 75-77. BARKLA . D. H., AN D TUTTON. P. J. M. (1977). Surface JAIN, S. K.. AND SUBRAHMANVAm. D. (1978

  4. Group Γ (2) and the fractional quantum Hall effect

    NASA Astrophysics Data System (ADS)

    Georgelin, Yvon; Wallet, Jean-Christophe

    1997-02-01

    We analyze the action of the inhomogeneous modular group Γ (2) on the three cusps of its principal fundamental domain in the Poincaré half plane. From this, we obtain an exhaustive classification of the fractional quantum Hall numbers. This classification, in which the integer and the fractional states appear on an equal level, is somehow similar to the one given by Jain. We also present some resulting remarks concerning direct phase transitions between the different quantum Hall states.

  5. Rashtriya Swayamsewak Sangh (RSS): History, Ideology and Its Influences on Indian Policy Towards Pakistan

    DTIC Science & Technology

    2015-05-21

    www.ciaonet.org/pbei/csis/sam/sam55/. 32 Pathak, K. K. Of Jaswant Singh, the BJP and the RSS. Mumbai : The Rajaji Foundation, 2010. Accessed 10 August...common holy ground, a common blood and a common culture . It is also noteworthy to mention that Buddhists, Jains and Sikhs were included in this...martin-marty/hindu-fundamentalism _b_5352547.html . 71 Ibid. 72 Pathak, K. K. Of Jaswant Singh, the BJP and the RSS. Mumbai : The Rajaji

  6. Weighted Parzen Windows for Pattern Classification

    DTIC Science & Technology

    1994-05-01

    Nearest-Neighbor Rule The k-Nearest-Neighbor ( kNN ) technique is nonparametric, assuming nothing about the distribution of the data. Stated succinctly...probabilities P(wj I x) from samples." Raudys and Jain [20:255] advance this interpretation by pointing out that the kNN technique can be viewed as the...34Parzen window classifier with a hyper- rectangular window function." As with the Parzen-window technique, the kNN classifier is more accurate as the

  7. New communications strategy insures hospital system's future.

    PubMed

    Shinkman, Ron

    2002-01-01

    According to Ron Shinkman, a veteran healthcare writer, Chief Executive Officer Ken Buser deserves much of the credit for improving the visibility and reputation of All Saints Healthcare, Racine, Wis.

  8. Mitchell Receives 2013 Ronald Greeley Early Career Award in Planetary Science: Citation

    NASA Astrophysics Data System (ADS)

    McKinnon, William B.

    2014-07-01

    The Greeley Early Career Award is named for pioneering planetary scientist Ronald Greeley. Ron was involved in nearly every major planetary mission from the 1970s until his death and was extraordinarily active in service to the planetary science community. Ron's greatest legacies, however, are those he mentored through the decades, and it is young scientists whose work and promise we seek to recognize. This year's Greeley award winner is Jonathan L. Mitchell, an assistant professor at the University of California, Los Angeles (UCLA). Jonathan received his Ph.D. from the University of Chicago, and after a postdoc at the Institute for Advanced Studies in Princeton, he joined the UCLA faculty, where he holds a joint appointment in Earth and space sciences and in atmospheric sciences.

  9. A modified version of fluctuating asymmetry, potential for the analysis of Aesculus hippocastanum L. compound leaves.

    PubMed

    Velickovic, Miroslava

    2008-01-01

    My research interest was to create a new, simple and tractable mathematical framework for analyzing fluctuating asymmetry (FA) in Aesculus hippocastanum L. palmately compound leaves (each compound leaf with 7 obviate, serrate leaflets). FA, being random differences in the development of both sides of a bilaterally symmetrical character, has been proposed as an indicator of environmental and genetic stress. In the present paper the well-established Palmer's procedure for FA has been modified to improve the suitability of the chosen index (FA1) to be used in compound leaf asymmetry analysis. The processing steps are described in detail, allowing us to apply these modifications for the other Palmer's indices of FA as well as for the compound leaves of other plant species.

  10. New stewards of the environment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tucker, W.

    1983-06-01

    Environmentalists are getting interested in the free market and are moving toward supporting complete deregulation of energy prices. Christopher Palmer, the National Audubon Society's director of energy and environment, says, There is no way you can use energy efficiently when you have price controls. Environmental groups are particularly unhappy with the Synthetic Fuels Corporation and the Clinch River Breeder Reactor; they will waste more energy than they make, complains Palmer. When resources are cheap or free, they tend to be abused. Environmentalists have discovered the market helps allay this overuse. Ironically, this turnaround in philosophy turns environmentalists into political landlords,more » a new role of privileged minority, trying to play steward to the nation's resources.« less

  11. Impact of Triticum mosaic virus infection on hard winter wheat milling and bread baking quality.

    PubMed

    Miller, Rebecca A; Martin, T Joe; Seifers, Dallas L

    2012-03-15

    Triticum mosaic virus (TriMV) is a newly discovered wheat virus. Information regarding the effect of wheat viruses on milling and baking quality is limited. The objective of this study was to determine the impact of TriMV infection on the kernel characteristics, milling yield and bread baking quality of wheat. Commercial hard winter varieties evaluated included RonL, Danby and Jagalene. The TriMV resistance of RonL is low, while that of Danby and Jagalene is unknown. KS96HW10-3, a germplasm with high TriMV resistance, was included as a control. Plots of each variety were inoculated with TriMV at the two- to three-leaf stage. Trials were conducted at two locations in two crop years. TriMV infection had no effect on the kernel characteristics, flour yield or baking properties of KS96HW10-3. The effect of TriMV on the kernel characteristics of RonL, Danby and Jagalene was not consistent between crop years and presumably an environmental effect. The flour milling and bread baking properties of these three varieties were not significantly affected by TriMV infection. TriMV infection of wheat plants did not affect harvested wheat kernel characteristics, flour milling properties or white pan bread baking quality. Copyright © 2011 Society of Chemical Industry.

  12. Effects of metastable species in helium and argon atmospheric pressure plasma jets (APPJs) on inactivation of periodontopathogenic bacteria

    NASA Astrophysics Data System (ADS)

    Yoon, Sung-Young; Kim, Kyoung-Hwa; Seol, Yang-Jo; Kim, Su-Jeong; Bae, Byeongjun; Huh, Sung-Ryul; Kim, Gon-Ho

    2016-05-01

    The helium and argon have been widely used as discharge gases in atmospheric pressure plasma jets (APPJs) for bacteria inactivation. The APPJs show apparent different in bullet propagation speed and bacteria inactivation rate apparently vary with discharge gas species. This work shows that these two distinctive features of APPJs can be linked through one factor, the metastable energy level. The effects of helium and argon metastable species on APPJ discharge mechanism for reactive oxygen nitrogen species (RONS) generation in APPJs are investigated by experiments and numerical estimation. The discharge mechanism is investigated by using the bullet velocity from the electric field which is obtained with laser induced fluorescence (LIF) measurement. The measured electric field also applied on the estimation of RONS generation, as electron energy source term in numerical particle reaction. The estimated RONS number is verified by comparing NO and OH densities to the inactivation rate of periodontitis bacteria. The characteristic time for bacteria inactivation of the helium-APPJ was found to be 1.63 min., which is significantly less than that of the argon-APPJ, 12.1 min. In argon-APPJ, the argon metastable preserve the energy due to the lack of the Penning ionization. Thus the surface temperature increase is significantly higher than helium-APPJ case. It implies that the metastable energy plays important role in both of APPJ bullet propagation and bacteria inactivation mechanism.

  13. 78 FR 56744 - Notice of Permit Applications Received Under the Antarctic Conservation Act of 1978 (Pub. L. 95-541)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-13

    ... (ASMA 7). All materials collected would be salvaged; the applicant would not interact with live animals... birds and mammals. Location ASPA 149 Cape Shireff and ASMA 7 Southwest Anvers Island (Palmer Station...

  14. 36 CFR 242.23 - Rural determinations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., Salamatof, Kalifonsky, Kasilof, and Clam Gulch; (6) Ketchikan area—including all parts of the road system...—including Wasilla, Palmer, Sutton, Big Lake, Houston, Point MacKenzie, and Bodenburg Butte. (b) [Reserved...

  15. Problems in Relating Soil to Site Index For Southern Hardwoods

    Treesearch

    W. M. Broadfoot

    1969-01-01

    Various soil-site characters were correlated with height growth of Liquidambar styraciflua L., Quercus falcata var. pagodaefolia Ell., Q. nigra L., Q. phellos L., Q. nutallii Palmer, Fraxinus pennsylvanica Marsh., and Populus...

  16. 75 FR 77652 - Notice of Intent to Prepare a Resource Management Plan for the Battle Mountain District and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-13

    ... agencies where appropriate. (7) The planning process will use and observe principles of multiple use and..., sociology and economics, and Geographic Information Systems. Authority: 40 CFR 1501.7, 43 CFR 1610.2. Ron...

  17. Endogenous 6-Hydroxylmelatonin Excretion and Subsequent Risk of Breast Cancer: A Prospective Study

    DTIC Science & Technology

    2006-03-01

    Prevention and Biomarkers of Susceptibility (in press , BBA-Reviews on Cancer) 8 3) Barba M, Cavalleri A, Schünemann HJ, Krogh V, Micheli A, Evangelista A...diagnosed with asthma or COPD (in press , Eur J Clin Nutr) 13) Colombo C, Muti P, Pala V, Cavalleri A, Venturelli E, Locardi M, Berrino F, Secreto...applications (Yu HS & Reiter R, eds) CRC Press , Boca Raton, FL, pp. 447-475, 1993. Bartsch C. Bartsch H. Jain AK. Laumas KR. Wetterberg L. Urinary

  18. Military Families: A Selected Bibliography

    DTIC Science & Technology

    2011-08-01

    34 Armed Forces & Society 30, no. 1 (Fall 2003): 7-24. Sage 6 Darwin, Jaine. "When War Hits Home." Proceedings: U.S. Naval Institute 137, no. 2...of American Families on the Homefront . Boston: Houghton Mifflin, 2006. 317pp. (DS79.76 .H25 2006) Hightower, Kathie. Help! I’m a Military Spouse—I...College. The Battlebook III: A Guide for Spouses in Leadership Roles; Spouses’ Project 2007. Carlisle Barracks: U.S. Army War College, 2007. 1 vol

  19. Bioblendstocks that Enable High Efficiency Engine Designs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McCormick, Robert L.; Fioroni, Gina M.; Ratcliff, Matthew A.

    2016-11-03

    The past decade has seen a high level of innovation in production of biofuels from sugar, lipid, and lignocellulose feedstocks. As discussed in several talks at this workshop, ethanol blends in the E25 to E50 range could enable more highly efficient spark-ignited (SI) engines. This is because of their knock resistance properties that include not only high research octane number (RON), but also charge cooling from high heat of vaporization, and high flame speed. Emerging alcohol fuels such as isobutanol or mixed alcohols have desirable properties such as reduced gasoline blend vapor pressure, but also have lower RON than ethanol.more » These fuels may be able to achieve the same knock resistance benefits, but likely will require higher blend levels or higher RON hydrocarbon blendstocks. A group of very high RON (>150) oxygenates such as dimethyl furan, methyl anisole, and related compounds are also produced from biomass. While providing no increase in charge cooling, their very high octane numbers may provide adequate knock resistance for future highly efficient SI engines. Given this range of options for highly knock resistant fuels there appears to be a critical need for a fuel knock resistance metric that includes effects of octane number, heat of vaporization, and potentially flame speed. Emerging diesel fuels include highly branched long-chain alkanes from hydroprocessing of fats and oils, as well as sugar-derived terpenoids. These have relatively high cetane number (CN), which may have some benefits in designing more efficient CI engines. Fast pyrolysis of biomass can produce diesel boiling range streams that are high in aromatic, oxygen and acid contents. Hydroprocessing can be applied to remove oxygen and consequently reduce acidity, however there are strong economic incentives to leave up to 2 wt% oxygen in the product. This oxygen will primarily be present as low CN alkyl phenols and aryl ethers. While these have high heating value, their presence in

  20. ScienceCast 24: Bright Perseids Photographed

    NASA Image and Video Library

    2011-08-18

    On August 13th, space station astronaut Ron Garan photographed a centimeter-sized chunk of comet debris disintegrating in Earth's atmosphere. His rare photo of a meteor from Earth orbit is a must-see.

  1. Garan exercises on the CEVIS

    NASA Image and Video Library

    2011-05-11

    ISS027-E-030045 (11 May 2011) --- NASA astronaut Ron Garan, Expedition 27 flight engineer, exercises on the Cycle Ergometer with Vibration Isolation System (CEVIS) in the Destiny laboratory of the International Space Station.

  2. Simulation design of uniform low turn-on voltage and high reverse blocking AlGaN/GaN power field effect rectifier with trench heterojunction anode

    NASA Astrophysics Data System (ADS)

    Wang, Fangzhou; Chen, Wanjun; Wang, Zeheng; Sun, Ruize; Wei, Jin; Li, Xuan; Shi, Yijun; Jin, Xiaosheng; Xu, Xiaorui; Chen, Nan; Zhou, Qi; Zhang, Bo

    2017-05-01

    To achieve uniform low turn-on voltage and high reverse blocking capability, an AlGaN/GaN power field effect rectifier with trench heterojunction anode (THA-FER) is proposed and investigated in this work which includes only simulated data and no real experimental result. VT has a low saturation value when trench height (HT) is beyond 300 nm, confirming it is possible to control the VT accurately without precisely controlling the HT in the THA-FER. Meanwhile, high HT anode reduces reverse leakage current and yields high breakdown voltage (VB). A superior high Baliga's Figure of Merits (BFOM = VB2/Ron,sp, Ron,sp is specific-on resistance) of 1228 MW/cm2 reveals the THA-FER caters for the demands of high efficiency GaN power applications.

  3. Value of Adaptive Drought Forecasting and Management for the ACF River Basin in the Southeast U.S.

    NASA Astrophysics Data System (ADS)

    Georgakakos, A. P.; Kistenmacher, M.

    2016-12-01

    In recent times, severe droughts in the southeast U.S. occur every 6 to 10 years and last for up to 4 years. During such drought episodes, the ACF River Basin supplies decline by up to 50 % of their normal levels, and water stresses increase rather markedly, exacerbating stakeholder anxiety and conflicts. As part of the ACF Stakeholder planning process, GWRI has developed new tools and carried out comprehensive assessments to provide quantitative answers to several important questions related to drought prediction and management: (i) Can dry and wet climatic periods be reliably anticipated with sufficiently long lead times? What drought indices can support reliable, skillful, and long-lead forecasts? (ii) What management objectives can seasonal climate forecasts benefit? How should benefits/impacts be shared? (iii) What operational adjustments are likely to mitigate stakeholder impacts or increase benefits consistent with stakeholder expectations? Regarding drought prediction, a large number of indices were defined and tested at different basin locations and lag times. These included local/cumulative unimpaired flows (UIFs) at 10 river nodes; Mean Areal Precipitation (MAP); Standard Precipitation Index (SPI); Palmer Drought Severity Index; Palmer Modified Drought Index; Palmer Z-Index; Palmer Hydrologic Drought Severity Index; and Soil Moisture—GWRI watershed model. Our findings show that all ACF sub-basins exhibit good forecast skill throughout the year and with sufficient lead time. Index variables with high explanatory value include: previous UIFs, soil moisture states (generated by the GWRI watershed model), and PDSI. Regarding drought management, assessments with coupled forecast-management schemes demonstrate that the use of adaptive forecast-management procedures improves reservoir operations and meets basin demands more reliably. Such improvements can support better management of lake levels, higher environmental and navigation flows, higher dependable

  4. Effects of Crown Position and Initial Spacing on Foliar Nutrient Composition of Seven Bottomland Hardwoods

    Treesearch

    Harvey E. Kennedy

    1993-01-01

    Seven plantation-grown bottomland hardwoods, sweetgum (Liquidambar stryaciflua L.), green ash (Fraxinus pennsylvanica Marsh.), American sycamore (Platanus occidentalis L.), water oak (Quercus nigra L.), Nuttall oak (Q. nuttallii Palmer), cherrybark oak (Q. falcata var.

  5. Garan and Coleman in Node 1

    NASA Image and Video Library

    2011-04-15

    ISS027-E-013097 (15 April 2011) --- NASA astronauts Ron Garan and Cady Coleman, both Expedition 27 flight engineers, work with extravehicular activity (EVA) grease guns in the Unity node of the International Space Station.

  6. Garan and Coleman in Node 1

    NASA Image and Video Library

    2011-04-15

    ISS027-E-013096 (15 April 2011) --- NASA astronauts Ron Garan and Cady Coleman, both Expedition 27 flight engineers, work with extravehicular activity (EVA) grease guns in the Unity node of the International Space Station.

  7. 78 FR 67333 - Performance Review Board Membership

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-12

    .... Arnold William G. Bostic, Jr. Stephen B. Burke Joanne Buenzli Crane Susan R. Helper Ron S. Jarmin Enrique... Stephens Sonja Steptoe Frank A. Vitrano Katherine K. Wallman Adam Wilczewski The term of each PRB member...

  8. Targeting the Ron-Dek Signaling Axis in Breast Cancer

    DTIC Science & Technology

    2015-09-01

    myeloid cells exacerbate LPS-induced acute lung injury in the murine lung. Innate immunity. 2011; 17:499–507. 25. Stuart WD, Kulkarni RM, Gray JK...activation in human and murine breast cancer cell lines induces the accumulation of Dek protein. This accumulation of Dek is significant as Dek...overexpression in breast cancer cell lines leads to increases in cell growth and migration while Dek depletion in breast cancer cells leads to dramatic

  9. Targeting the Ron-DEK Signaling Axis in Breast Cancer

    DTIC Science & Technology

    2014-09-01

    Health Services Grants R01CA116316 ( SIW ), R01HL875109 (JAC), T32ES007250 (AKA), T32CA117846-07 (PKW) and T32CA11784 (SEW and NMB), Department of Defense...Grant W81XWH-12-1-0194 ( SIW and SEW) and the Veteran’s Administration Grant BX000803 (SEW). JS-W is supported by the Government of the Spanish Junta de

  10. Targeting the Ron-DEK Signaling Axis in Breast Cancer

    DTIC Science & Technology

    2014-09-01

    Public Health Services Grants R01CA116316 ( SIW ), R01HL875109 (JAC), T32ES007250 (AKA), T32CA117846-07 (PKW) and T32CA11784 (SEW and NMB), Department of...Defense Grant W81XWH-12-1-0194 ( SIW and SEW) and the Veteran’s Administration Grant BX000803 (SEW). JS-W is supported by the Government of the Spanish

  11. KSC-94pc1510

    NASA Image and Video Library

    1994-12-13

    KENNEDY SPACE CENTER, FLA. -- Film director Ron Howard (right) and a production crew, along with actor Tom Hanks (left), are filming a number of scenes at KSC for an upcoming film about the Apollo 13 mission.

  12. iss028e026402

    NASA Image and Video Library

    2011-08-17

    ISS028-E-026402 (17 Aug. 2011) --- NASA astronaut Ron Garan, Expedition 28 flight engineer, works with the Combustion Integrated Rack (CIR) Fluids and Combustion Facility (FCF) in the Destiny laboratory of the International Space Station.

  13. iss028e026400

    NASA Image and Video Library

    2011-08-17

    ISS028-E-026400 (17 Aug. 2011) --- NASA astronaut Ron Garan, Expedition 28 flight engineer, works with the Combustion Integrated Rack (CIR) Fluids and Combustion Facility (FCF) in the Destiny laboratory of the International Space Station.

  14. 6 Common Cancers - Colorectal Cancer

    MedlinePlus

    ... Bar Home Current Issue Past Issues 6 Common Cancers - Colorectal Cancer Past Issues / Spring 2007 Table of Contents For ... colon cancer. Photo: AP Photo/Ron Edmonds Colorectal Cancer Cancer of the colon (large intestine) or rectum ( ...

  15. SCREENOP: A Computer Assisted Model for ASW (Anti-Submarine Warfare) Screen Design.

    DTIC Science & Technology

    1983-09-01

    AD-A736 892 SCREENOP: A COMPUTER ASSISTED MODEL FOR ASW I (ANTISUBMARINE WARFARE) SCREEN DESIGN (S) NAVAL , POSTGRADUATE SCHOOL MONTEREY CA W J...POSTGRADUATE SCHOOL £ Monterey, California DTIC $ELECTE f JAIN17 1984J THESIS SCREENOP: A COMPUTER ASSISTED MODEL FOR ASH SCREEN DESIGN by William Joseph... Design SL AVSIUACY rCin do msiwoS 0ddst aO memeo mE Idm.M& 6y 61-k imwel) This chesis is a description of the Naval Postgraduate School’s version of

  16. The H-Function and Probability Density Functions of Certain Algebraic Combinations of Independent Random Variables with H-Function Probability Distribution

    DTIC Science & Technology

    1981-05-01

    functions and the H- function," Boletin do la Academia de Ciencias Fisicas Matematicas v Naturales (Caracas), 31, 95- 102 (1971). 120. Jain, U. C...Society, 37, 329- 334 (1973). 32. Oliver, M. L., and S. L. Kalla, "On the derivative of Fox’s H- function," (Spanish) Acta 14,dlcana de Ciencia -v...34 Universidade de Lisboa Revista de Faculdade de Ciencias FMatematicas, II, Series A, 13, 109-114 (1969-70). 92. Bajpai, S. D., "On some results involving Fox’s H

  17. Electron Interactions with Non-Linear Polyatomic Molecules and their Radicals and Ions

    DTIC Science & Technology

    1991-06-01

    is the usual antisymmetrization operator to ensure Pauli principle. In the expansion (4.1.2), we have neglected the correlation functions of the (N...Kochem, K M Scheuerlein, K Jung and H Ehrhardt, J. Phys. B19, 3625 (1986). [27]. A Jain, Ph.D. thesis (Queen’s University, Belfast) 1983. [2S]. D M...Winstead and V McLoy, Phys. Rev. A42, 5357 (1990). [52]. R Muiller, K Jung , K H Kochem, W Sohn and H Ehrhardt, J. Phys. B 18, 3971 (1985). [53]. L

  18. 6. Historic American Buildings Survey, Stanley P. Mixon, Photographer March ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Historic American Buildings Survey, Stanley P. Mixon, Photographer March 28, 1940 EXTERIOR, DETAIL FROM NORTH: SHOWING OLDEST PORTION OF HOUSE. - Palmer Northrup House, 7919 Post Road (U.S. Route Alternate 1), Kingston, Washington County, RI

  19. 1300129

    NASA Image and Video Library

    2013-03-11

    MSFC DIRECTOR PATRICK SCHEUERMANN CUTS RIBBON AT DEDICATION OF MARSHALL ROOM AT HUNTSVILLE-MADISON COUNTY CHAMBER OF COMMERCE, 3/11/13. TROY TRULOCK (L), MAYOR OF MADISON, AL AND RON POTEAT, (R), BOARD CHAIR, CHAMBER OF COMMERCE

  20. Garan in sleeping bag in Columbus module

    NASA Image and Video Library

    2008-06-09

    S124-E-007980 (9 June 2008) --- Astronaut Ron Garan, STS-124 mission specialist, sleeps in his sleeping bag in the Columbus laboratory of the International Space Station while Space Shuttle Discovery is docked with the station.

  1. ARC-1993-AC93-0608-41

    NASA Image and Video Library

    1993-12-12

    Life from other Worlds' with McNair Middle School TROV robot explores under Antarctic ice - image of Eric James, Ron Schutz, and Wade Sisler of the Photographic Technology Branch co-ordinating remote shots from Antarctic to Ames

  2. Office of Naval Research Graduate Traineeship Award in Ocean Acoustics for Ankita Deepak Jain

    DTIC Science & Technology

    2012-09-30

    Ziegesar, O., “Population structure of nuclear and mitochondrial DNA variation among humpback whales in the North Pacific,” Molecular Ecology 7(6): 695-707 (1998) ...ocean, and correlating measured noise with local wind speed. Mexican waters of the North Pacific Ocean are known to be wintering grounds for humpback ... whales [10]. During this experiment, many marine mammal vocalizations were recorded by the deployed hydrophones. We are in the process of

  3. 75 FR 7986 - Blueberry and Hass Avocado Promotion, Research, and Information Orders; Section 610 Reviews

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-23

    ....gov . FOR FURTHER INFORMATION CONTACT: Jeanette Palmer, Marketing Specialist, Research and [email protected] regarding blueberries; or Maureen T. Pello, Marketing Specialist, Research and... DEPARTMENT OF AGRICULTURE Agricultural Marketing Service 7 CFR Parts 1218 and 1219 [Document...

  4. Bernoulli's Challenge

    NASA Astrophysics Data System (ADS)

    Bouffard, Karen

    1999-01-01

    This month's Olympic activity was brought to the Eastern Massachusetts Physics Olympics group by Ron DeFronzo of Pawtucket, Rhode Island. Using a hair dryer, contestants must maneuver a Ping-Pong ball into a three-dimensional "bullseye" target.

  5. Publications - GMC 203 | Alaska Division of Geological & Geophysical

    Science.gov Websites

    DGGS GMC 203 Publication Details Title: A summary of the data resulting from the 1991 MMS geologic Turner, Ron, and Core Laboratories, 1992, A summary of the data resulting from the 1991 MMS geologic

  6. Integrated palmer amaranth management in glufosinate-resistant cotton

    USDA-ARS?s Scientific Manuscript database

    Two separate three year field experiments were conducted to evaluate: 1) the role of soil-inversion, cover crops and herbicide regimes for Amaranthus palmeri between-row (BR) and within-row (WR) management in glufosinate-resistant cotton and 2) the role of soil inversion, cover crops and spring til...

  7. Enhanced phytoremediation of arsenic contaminated land.

    PubMed

    Jankong, P; Visoottiviseth, P; Khokiattiwong, S

    2007-08-01

    In an attempt to clean up arsenic (As) contaminated soil, the effects of phosphorus (P) fertilizer and rhizosphere microbes on arsenic accumulation by the silverback fern, Pityrogramma calomelanos, were investigated in both greenhouse and field experiments. Field experiments were conducted in Ron Phibun District, an As-contaminated area in Thailand. Soil (136-269 microg As g(-1)) was collected there and used in the greenhouse experiment. Rhizosphere microbes (bacteria and fungi) were isolated from roots of P. calomelanos growing in Ron Phibun District. The results showed that P-fertilizer significantly increased plant biomass and As accumulation of the experimental P. calomelanos. Rhizobacteria increased significantly the biomass and As content of the test plants. Thus, P-fertilizer and rhizosphere bacteria enhanced As-phytoextraction. In contrast, rhizofungi reduced significantly As concentration in plants but increased plant biomass. Therefore, rhizosphere fungi exerted their effects on phytostabilization.

  8. Quality of Surface Water before Implementation of a Flood-Control Project in Chaska, Minnesota.

    DTIC Science & Technology

    1981-12-01

    reports from 165 authors (Palmer, 1968). Scenedesmus , Oscillatoria, Chlamydomonas, and Ankistrodesmus, all identified in the samples, are in the top 10...SCENEDESMACEAE .... CRUCIGENIA dI 4 ...... 550 11 .... SCENEDESMUS 81 $1 .... 1100# 21 .TETRASPORALES ... COCCOMYXACEAE .. ELAKATOTHRIX ........ 160 3

  9. Publications - GMC 154 | Alaska Division of Geological & Geophysical

    Science.gov Websites

    DGGS GMC 154 Publication Details Title: Geochemical and pellet data of an 8060 foot depth core sample Reference Mickey, M.B., and Brockway, Ron, 1990, Geochemical and pellet data of an 8060 foot depth core

  10. KSC-94PC-1509

    NASA Image and Video Library

    1994-12-13

    KENNEDY SPACE CENTER, FLA. -- Film director Ron Howard [right, with head phones] and a production crew, along with actor Tom Hanks [center], are filming a number of scenes at KSC for an upcoming film about the Apollo 13 mission.

  11. James F. McGinnis, D.C., N.D., C.P. (1873-1947): spinographer, educator, marketer and bloodless surgeon.

    PubMed

    Keating, J C

    1998-12-01

    Perhaps best remembered for his contributions to B.J. Palmer's earliest developments in spinography, James F. McGinnis also pioneered in marketing methods while a straight chiropractic practitioner in Iowa. His advertising brought him to the attention of organized medicine, which sought his prosecution. Relocating to California in the early 1920s, he broadened his scope of practice and earned a naturopathic doctorate. In the 1930s he became one of the best known of several chiropractic bloodless surgeons and traveled around the nation to teach his methods. Although initially a passionate member of the Universal Chiropractors Association and receptive to Palmer's introduction of the neurocalometer, McGinnis eventually changed his political allegiance and became an active member of the National Chiropractic Association. He died in 1947 while on a teaching tour of Claifornia's San Joaquin Valley.

  12. Optical parameters of leaves of seven weed species

    NASA Technical Reports Server (NTRS)

    Gausman, H. W.; Menges, R. M.; Richardson, A. J.; Walter, H.; Rodriguez, R. R.; Tamez, S. (Principal Investigator)

    1982-01-01

    Absorption coefficient (k), infinite reflectance (R inf.) and scattering coefficient (s) were tabulated for five wavelengths and analyzed for statistical differences for seven weed species. The wavelengths were: 0.55, 0.65, 0.85, 1.65, and 2.20 microns. The R inf. of common lambsquarters (Chenopodium album L.), johnsongrass (Sorghum halepense L. Pers.), and annual sowthistle (Sonchus oleraceus L.) leaves at the 0.85 micron wavelength were significantly (p = 0.05) higher than for sunflower (Helianthus annuus L.), ragweed parthenium (parthenium hysterophorus L.), or London rocket (Sisymbrium irio L.). Annual sowthistle had the largest k value, and Palmer amaranth (Amaranthus palmeri S. Wats.) had the smallest k value at the 0.65 micron chlorophyll absorption wavelength. In general, johnsongrass, ragweed parthenium, and London rocket had the largest s values among the five wavelengths, whereas annual sowthistle and Palmer amaranth were usually lowest.

  13. Spectral discrimination of two pigweeds from cotton with different leaf colors

    USDA-ARS?s Scientific Manuscript database

    To implement strategies to control Palmer amaranth (Amaranthus palmeri S. Wats.) and redroot pigweed (Amaranthus retroflexus L.) infestations in cotton (Gossypium hirsutum L.) production systems, managers need effective techniques to identify the weeds. Leaf light reflectance measurements have shown...

  14. Sfg

    NASA Astrophysics Data System (ADS)

    Fischer, R. X.; Baur, W. H.

    This document is part of Subvolume E `Zeolite-Type Crystal Structures and their Chemistry. Framework Type Codes RON to STI' of Volume 14 `Microporous and other Framework Materials with Zeolite-Type Structures' of Landolt-Börnstein Group IV `Physical Chemistry'.

  15. ARC-1986-AC86-0746-2

    NASA Image and Video Library

    1986-10-10

    Ames Director William 'Bill' Ballhaus (center left) joins visitor Sir Jeffrey Pope from Royla Aircraft Industry, England (center right) at the NAS Facility Cray 2 computer with Ron Deiss, NAS Deputy Manager (L) and Vic Peterson, Ames Deputy Director (R).

  16. A LOTUS NOTES APPLICATION FOR PREPARING, REVIEWING, AND STORING NHEERL RESEARCH PROTOCOLS

    EPA Science Inventory

    Upon becoming QA Manager of the Health Effects Research Laboratory (HERL) in 1990, Ron became aware of the need to simplify and streamline the research planning process that Laboratory Principal Investigators (Pls) faced. Appropriately, animal studies require close scrutiny, both...

  17. Contingency Contracting Guide/Lessons for Navy Contracting Officers

    DTIC Science & Technology

    2004-06-01

    objective. The late Secretary Ron Brown, and many other government and industry leaders sacrificed their lives pursuing the economic...telephones and copiers. Office supplies such as paper, pens, staplers and staples, date stamps, post-it notes, three ring binders, hole punchers

  18. Quasiparticle interactions in fractional quantum Hall systems: Justification of different hierarchy schemes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wojs, Arkadiusz; Institute of Physics, Wroclaw University of Technology, 50-370 Wroclaw,; Quinn, John J.

    2000-01-15

    The pseudopotentials describing the interactions of quasiparticles in fractional quantum Hall (FQH) states are studied. Rules for the identification of incompressible quantum fluid ground states are found, based upon the form of the pseudopotentials. States belonging to the Jain sequence {nu}=n(1+2pn){sup -1}, where n and p are integers, appear to be the only incompressible states in the thermodynamic limit, although other FQH hierarchy states occur for finite size systems. This explains the success of the composite Fermion picture. (c) 2000 The American Physical Society.

  19. Construction of a Simple Actograph

    ERIC Educational Resources Information Center

    Quackenbush, Roger E.

    1977-01-01

    Diagrams and explains construction of an actograph which quantitatively records daily movements of animals for a 24-hour period. Combines use of a kymograph and the teetering box of Palmer. Biorhythm activities with fiddler crabs, cockroaches, and hamsters are suggested. (CS)

  20. The increasing sacrcity of red oaks in Mississippi river floodplain forestS: Influence of the residual overstory

    Treesearch

    Chadwick Dearing Oliver; E.C. Burkhardt; Daniel A. Skojac

    2005-01-01

    Red oaks - cherrybark oak (Quercus pagoda Raf.) willow oak (Quercus phellos L.), water oak (Quercus nigra L.), and Nuttall oak (Quercus texana Buckley; aka: Quercus nuttallii Palmer) - are not regrowing in Mississippi Delta river floodplain forests in the southeastern United...

  1. Fort Hood Building and Landscape Inventory with WWII and Cold War Context

    DTIC Science & Technology

    2007-03-01

    barracks, 1970s (NARA)........................................................... 112 Figure 37. Palmer Movie Theater (NARA...revised 1953) showing layout of Hood Village and trailer park (Fort Hood...arms ammunition storage building #92012 (ERDC-CERL, 2004). ......... 260 Figure 163: Radio reception building #92063 (ERDC-CERL, 2004

  2. Evaluation of cotton responses to fomesafen-based treatments applied preemergence

    USDA-ARS?s Scientific Manuscript database

    Fomesafen provides effective control of glyphosate resistant Palmer amaranth in cotton. However, cotton seedling injury is possible when fomesafen applied pre-emergence (PRE). Therefore, greenhouse and field experiments were conducted at Athens GA and six locations in Alabama and Georgia, respecti...

  3. FEU Technology Digest No. 2.

    ERIC Educational Resources Information Center

    Further Education Unit, London (England).

    This publication contains a glossary of acronyms; an editorial (Ingram); "Integrative Assignments and Design" (Biles, Palmer); "Computer-Based Education: A Student's Response" (Landau); "Taking the RISC [Reduced Instruction Set Computer] in FHE [Further and Higher Education]" (Meeke); "Engineering Education in…

  4. Obituary: Ronald N. Bracewell, 1921-2007

    NASA Astrophysics Data System (ADS)

    Petrosian, Vahé

    2009-01-01

    Ronald N. Bracewell, Professor Emeritus (since 1991) of Electrical Engineering at Stanford University, and a true renaissance man of science, died of a heart attack on 12 August 2007 at his home. Ron Bracewell was born in Sydney, Australia, on 22 July 1921, one of the two sons of Cecil and Valerie Bracewell. He graduated from the University of Sydney in 1941 and received his doctorate degree in physics from Cambridge University in 1949. During World War II, Ron worked in the Australian National Radar Establishment, where he designed and developed microwave radar equipment. Like several other World War II radar scientists, after the war he used this experience to pioneer the new field of radio astronomy. With J. L. Pawsey, in 1955 he published the first comprehensive textbook in this field entitled, Radio Astronomy. Bracewell joined the Stanford Electrical Engineering faculty in 1955, and from 1974 on he held the first prestigious Lewis Terman professorship. He was awarded the Outstanding Service Award of the department in 1984. In 1988, he was named an officer of the Order of Australia--the Australian equivalent of Order of the British Empire. Soon after his arrival at Stanford, Bracewell designed and began building a solar spectroheliograph, consisting of thirty-two dish antennas in the form of a cross. This was completed in 1961 and provided daily maps of the Sun for more than a decade encompassing more than one solar activity cycle of eleven years. These maps were useful in predicting magnetic storms caused by solar activity and were used by NASA during the first landing on the Moon. In 1971 he started the building of a five-element radio interferometer, for observation of extragalactic radio sources, with the novel design of unequal spacing that gave the resolution of a ten-element array. Both telescopes are now dismantled. The common characteristics of these and other projects were that they were all built in-house with a limited budget, often a small fraction

  5. A drought severity climatology for the Carpathian Region using Sc-PDSI

    NASA Astrophysics Data System (ADS)

    Antofie, Tiberiu; Naumann, Gustavo; Spinoni, Jonathan; Weynants, Melanie; Szalai, Sandor; Szentimrey, Tamas; Bihari, Zita; Vogt, Jürgen

    2013-04-01

    Monthly grids of the self-calibrating Palmer Drought Severity Index (Sc-PDSI) have been calculated for the period 1961-2010 for the Carpathian Region (17˚-27˚E, 44˚-50˚N) with a spatial resolution of 0.1˚x 0.1˚. Using the Sc-PDSI and the assumptions of the Palmer Drought Model (PDM), the approximated precipitation required for drought termination (achieved when the Sc-PDSI turns back above -0.5) and amelioration (achieved when the Sc-PDSI value turns back above -2.0) are computed for periods of 1, 3, 6, and 9 months. The Sc-PDSI is based on a modified version of the Palmer Drought Severity Index (PDSI), first introduced by Palmer (1965) with the intent to measure the cumulative departure (related to local normal conditions) of moisture supply and demand. Due to its empirically derived climatic characteristic (K) and duration factors - limited to U.S. climatic conditions - Wells et al. (2004) improved it and transformed the PDSI into the Sc-PDSI, which is more appropriate for spatial comparisons in different climatic regions. The Sc-PDSI is based on the supply-and-demand concept of a complex water budget system based on precipitation and temperature records and also on the soil characteristics at any location. The inputs used in this study are the Available Water Capacity of the soil (AWC) derived from the soil texture (European Soil Database of JRC) with a spatial resolution of 0.1˚x0.1˚, Potential Evapo-Transpiration (PET), and 6 hydrological parameters of the soil water balance: recharge, runoff, loss, and their potential values (used in the calculation of Palmer's constants to define the normal climate for the specific location, i.e. the so called CAFEC). PET has been computed using the 0.1˚x 0.1˚ gridded monthly precipitation and mean temperature for 1961-2010 provided by the CARPATCLIM project in the framework of the construction of a Climate Atlas for the Carpathian Region. The Sc-PDSI focuses on the monthly anomalies of the soil moisture, thus it

  6. Effects of Heat of Vaporization and Octane Sensitivity on Knock-Limited Spark Ignition Engine Performance

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ratcliff, Matthew A; Burton, Jonathan L; Sindler, Petr

    Knock-limited loads for a set of surrogate gasolines all having nominal 100 research octane number (RON), approximately 11 octane sensitivity (S), and a heat of vaporization (HOV) range of 390 to 595 kJ/kg at 25 degrees C were investigated. A single-cylinder spark-ignition engine derived from a General Motors Ecotec direct injection (DI) engine was used to perform load sweeps at a fixed intake air temperature (IAT) of 50 degrees C, as well as knock-limited load measurements across a range of IATs up to 90 degrees C. Both DI and pre-vaporized fuel (supplied by a fuel injector mounted far upstream ofmore » the intake valves and heated intake runner walls) experiments were performed to separate the chemical and thermal effects of the fuels' knock resistance. The DI load sweeps at 50 degrees C intake air temperature showed no effect of HOV on the knock-limited performance. The data suggest that HOV acts as a thermal contributor to S under the conditions studied. Measurement of knock-limited loads from the IAT sweeps for DI at late combustion phasing showed that a 40 vol% ethanol (E40) blend provided additional knock resistance at the highest temperatures, compared to a 20 vol% ethanol blend and hydrocarbon fuel with similar RON and S. Using the pre-vaporized fuel system, all the high S fuels produced nearly identical knock-limited loads at each temperature across the range of IATs studied. For these fuels RON ranged from 99.2 to 101.1 and S ranged from 9.4 to 12.2, with E40 having the lowest RON and highest S. The higher knock-limited loads for E40 at the highest IATs examined were consistent with the slightly higher S for this fuel, and the lower engine operating condition K values arising from use of this fuel. The study highlights how fuel HOV can affect the temperature at intake valve closing, and consequently the pressure-temperature history of the end gas leading to more negative values of K, thereby enhancing the effect of S on knock resistance.« less

  7. Garan performs TCS Water Loop Degassing in Columbus

    NASA Image and Video Library

    2011-04-08

    ISS027-E-011325 (8 April 2011) --- NASA astronaut Ron Garan, Expedition 27 flight engineer, works on degassing the water loop of the running Water Pump Assembly 2 / Thermal Control System (WPA2/TCS) in the Columbus laboratory of the International Space Station.

  8. Garan performs TCS Water Loop Degassing in Columbus

    NASA Image and Video Library

    2011-04-08

    ISS027-E-011324 (8 April 2011) --- NASA astronaut Ron Garan, Expedition 27 flight engineer, works on degassing the water loop of the running Water Pump Assembly 2 / Thermal Control System (WPA2/TCS) in the Columbus laboratory of the International Space Station.

  9. The Application of SERS (Surface Enhanced Raman Scattering) to Study Surface Oxidation Reactions of Phosphonates.

    DTIC Science & Technology

    1988-02-15

    Center Attn: Dr. Ron Atkins Code 50C Chemistry Division Crane, Indiana 47522-5050 China Lake, California 93555 Scientific Advisor INaval Civil...Superintendent Marine Sciences Division Chemistry Division, Code 6100 San Diego, California 91232 Naval Research Laboratory Washington, D.C. 20375-5000 ,! .1

  10. jsc2014e031497

    NASA Image and Video Library

    2014-03-27

    DATE: 3-27-14.LOCATION: Bldg. 30 - FCR-1 (30M/231).SUBJECT: Expedition 39 flight controllers on console with Flight Director Ron Spencer watch the approach of the Soyuz 39 crew docking to the ISS from FCR-1..PHOTOGRAPHER: Lauren Harnett

  11. STS-131 Flight Directors

    NASA Image and Video Library

    2010-03-30

    JSC2010-E-045168 (30 March 2010) --- ISS flight directors for the STS-131/19A mission pose for a preflight group portrait at NASA's Johnson Space Center. Pictured from the left are Courtenay McMillan, Ed Van Cise and Ron Spencer.

  12. jsc2014e031517

    NASA Image and Video Library

    2014-03-27

    DATE: 3-27-14.LOCATION: Bldg. 30 - FCR-1 (30M/231).SUBJECT: Expedition 39 flight controllers on console with Flight Director Ron Spencer watch the approach of the Soyuz 39 crew docking to the ISS from FCR-1..PHOTOGRAPHER: Lauren Harnett

  13. jsc2014e031522

    NASA Image and Video Library

    2014-03-27

    DATE: 3-27-14.LOCATION: Bldg. 30 - FCR-1 (30M/231).SUBJECT: Expedition 39 flight controllers on console with Flight Director Ron Spencer watch the approach of the Soyuz 39 crew docking to the ISS from FCR-1..PHOTOGRAPHER: Lauren Harnett

  14. jsc2014e031513

    NASA Image and Video Library

    2014-03-27

    DATE: 3-27-14.LOCATION: Bldg. 30 - FCR-1 (30M/231).SUBJECT: Expedition 39 flight controllers on console with Flight Director Ron Spencer watch the approach of the Soyuz 39 crew docking to the ISS from FCR-1..PHOTOGRAPHER: Lauren Harnett

  15. jsc2014e031512

    NASA Image and Video Library

    2014-03-27

    DATE: 3-27-14.LOCATION: Bldg. 30 - FCR-1 (30M/231).SUBJECT: Expedition 39 flight controllers on console with Flight Director Ron Spencer watch the approach of the Soyuz 39 crew docking to the ISS from FCR-1..PHOTOGRAPHER: Lauren Harnett

  16. jsc2014e031521

    NASA Image and Video Library

    2014-03-27

    DATE: 3-27-14.LOCATION: Bldg. 30 - FCR-1 (30M/231).SUBJECT: Expedition 39 flight controllers on console with Flight Director Ron Spencer watch the approach of the Soyuz 39 crew docking to the ISS from FCR-1..PHOTOGRAPHER: Lauren Harnett

  17. iss028e035028

    NASA Image and Video Library

    2011-08-27

    ISS028-E-035028 (27 Aug. 2011) --- NASA astronaut Mike Fossum, Expedition 28 flight engineer, trims astronaut Ron Garan's hair in the Tranquility node of the International Space Station. Fossum used hair clippers fashioned with a vacuum device to garner freshly cut hair.

  18. iss028e035053

    NASA Image and Video Library

    2011-08-27

    ISS028-E-035053 (27 Aug. 2011) --- NASA astronaut Ron Garan, Expedition 28 flight engineer, trims astronaut Mike Fossum's hair in the Tranquility node of the International Space Station. Garan used hair clippers fashioned with a vacuum device to garner freshly cut hair.

  19. 77 FR 48491 - Regulatory New Drug Review: Solutions for Study Data Exchange Standards; Notice of Meeting...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-14

    ... INFORMATION CONTACT: Ron Fitzmartin, Office of Planning & Informatics, Center for Drug Evaluation and Research... limited. Send registration information (including name, title, firm name, country of citizenship, address, telephone and fax number, and email address) to Fatima Elnigoumi, Center for Drug Evaluation and Research...

  20. A&M. Hot liquid waste treatment building (TAN616). Camera facing east. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    A&M. Hot liquid waste treatment building (TAN-616). Camera facing east. Showing west facades of structure. Photographer: Ron Paarmann. Date: September 22, 1997. INEEL negative no. HD-20-1-1 - Idaho National Engineering Laboratory, Test Area North, Scoville, Butte County, ID

  1. QUALITY ASSURANCE IN RESEARCH LABORATORIES: RULES AND REASON

    EPA Science Inventory

    Quality Assurance in Research Laboratories: Rules and Reason

    Ron Rogers, Quality Assurance and Records Manager, Environmental Carcinogenesis Division, NHEERL/ORD/US EPA, Research Triangle Park, NC, 27709

    To anyone who has actively participated in research, as I have...

  2. The GaN trench gate MOSFET with floating islands: High breakdown voltage and improved BFOM

    NASA Astrophysics Data System (ADS)

    Shen, Lingyan; Müller, Stephan; Cheng, Xinhong; Zhang, Dongliang; Zheng, Li; Xu, Dawei; Yu, Yuehui; Meissner, Elke; Erlbacher, Tobias

    2018-02-01

    A novel GaN trench gate (TG) MOSFET with P-type floating islands (FLI) in drift region, which can suppress the electric field peak at bottom of gate trench during the blocking state and prevent premature breakdown in gate oxide, is proposed and investigated by TCAD simulations. The influence of thickness, position, doping concentration and length of the FLI on breakdown voltage (BV) and specific on-resistance (Ron_sp) is studied, providing useful guidelines for design of this new type of device. Using optimized parameters for the FLI, GaN FLI TG-MOSFET obtains a BV as high as 2464 V with a Ron_sp of 3.0 mΩ cm2. Compared to the conventional GaN TG-MOSFET with the same structure parameters, the Baliga figure of merit (BFOM) is enhanced by 150%, getting closer to theoretical limit for GaN devices.

  3. Characteristics of Superjunction Lateral-Double-Diffusion Metal Oxide Semiconductor Field Effect Transistor and Degradation after Electrical Stress

    NASA Astrophysics Data System (ADS)

    Lin, Jyh‑Ling; Lin, Ming‑Jang; Lin, Li‑Jheng

    2006-04-01

    The superjunction lateral double diffusion metal oxide semiconductor field effect has recently received considerable attention. Introducing heavily doped p-type strips to the n-type drift region increases the horizontal depletion capability. Consequently, the doping concentration of the drift region is higher and the conduction resistance is lower than those of conventional lateral-double-diffusion metal oxide semiconductor field effect transistors (LDMOSFETs). These characteristics may increase breakdown voltage (\\mathit{BV}) and reduce specific on-resistance (Ron,sp). In this study, we focus on the electrical characteristics of conventional LDMOSFETs on silicon bulk, silicon-on-insulator (SOI) LDMOSFETs and superjunction LDMOSFETs after bias stress. Additionally, the \\mathit{BV} and Ron,sp of superjunction LDMOSFETs with different N/P drift region widths and different dosages are discussed. Simulation tools, including two-dimensional (2-D) TSPREM-4/MEDICI and three-dimensional (3-D) DAVINCI, were employed to determine the device characteristics.

  4. Inactivation of myeloma cancer cells by helium and argon plasma jets: The effect comparison and the key reactive species

    NASA Astrophysics Data System (ADS)

    Chen, Zeyu; Cui, Qingjie; Chen, Chen; Xu, Dehui; Liu, Dingxin; Chen, H. L.; Kong, Michael G.

    2018-02-01

    In plasma cancer therapy, the inactivation of cancer cells under plasma treatment is closely related to the reactive oxygen and nitrogen species (RONS) induced by plasmas. Quantitative study on the plasma-induced RONS that related to cancer cells apoptosis is critical for advancing the research of plasma cancer therapy. In this paper, the effects of several reactive species on the inactivation of LP-1 myeloma cancer cells are comparatively studied with variable working gas composition, surrounding gas composition, and discharge power. The results show that helium plasma jet has a higher cell inactivation efficiency than argon plasma jet under the same discharge power. By comparing the concentration of aqueous phase reactive species and the cell inactivation efficiency under different working gases and discharge powers, it is demonstrated that the inactivation efficiency of LP-1 myeloma cancer cells is strongly correlated with the concentration of peroxynitrite (ONOOH/ONOO-).

  5. Grades as Predictors of College and Career Success: The Case of a Health-Related Institution.

    ERIC Educational Resources Information Center

    Tan, David L.

    1991-01-01

    Examined relationship between grades, academic performance, and career success in case of nontraditional, health-related educational institution (Palmer College of Chiropractic). Found direct relationship between entering grade point average and subsequent college performance. Relationship between good grades in professional schools and career…

  6. 76 FR 58059 - Investment Managers Series Trust, et al.; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-19

    ...] Investment Managers Series Trust, et al.; Notice of Application September 13, 2011. AGENCY: Securities and... approval and would grant relief from certain disclosure requirements. Applicants: Investment Managers... successors (any such entity, together with Palmer Square, an ``Adviser''); (b) uses the manager of managers...

  7. The Emotional Balancing Act of Teaching: A Burnout Recovery Plan

    ERIC Educational Resources Information Center

    Sproles, Karyn Z.

    2018-01-01

    This chapter integrates two of the most influential authorities on teaching, Robert Boice and Parker Palmer, into the system's approach to teaching articulated by Douglas Robertson in order to help college teachers find sustainable balance by acknowledging and managing emotions in the classroom.

  8. The Hangover: The Early and Lasting Effects of the Controversial Incorporation of X-Ray Technology into Chiropractic.

    PubMed

    Young, Kenneth J; Bakkum, Barclay W; Siordia, Lawrence

    2016-01-01

    Chiropractic first adopted the X-ray in 1910 for the purpose of demonstrating tiny misalignments of spinal bones, theorised to cause all disease, which they called chiropractic subluxations. This paper explores the apparent contradiction and resultant controversy of a system of natural healing adopting a medical technology. It centres on the actions of B.J. Palmer, the first chiropractor to use X-rays. It also clarifies details of Palmer's decision to incorporate the technology and interprets the change in the sociological context of boundary work. The continuing use of the subluxation paradigm for radiography by chiropractors has had a lingering effect on the profession, a metaphorical hangover of vitalism that is not consistent with modern healthcare practice. As a result of this conflict, arguments within the profession on the use of X-rays contribute to the continuing schism between evidence-based and subluxation-based chiropractors.

  9. Expedition 27 Docking

    NASA Image and Video Library

    2011-04-06

    Carmel Garan, center, wife of Expedition 27 NASA Flight Engineer Ron Garan, is seen at Russian Mission Control in Korolev, Russia speaking to her husband shortly after his arrival at the International Space Station on Thursday, April 7, 2011. Photo Credit: (NASA/Carla Cioffi)

  10. U.S. EPA, Pesticide Product Label, TOX-GUARD 9, 03/18/1983

    EPA Pesticide Factsheets

    2011-04-21

    ... TO:"(·Gl",\\Rll ~ 1:<- \\1,:;p,1 undtlut('li 'II ~~~(,IRl1y de.dgl)eQ atrcraft or J!~'Iund t'(i ... I rna" '''t..'dl',ln\\ dl~"\\'l:f 1,,\\" rof 1(". !o 10n mi"ron~ Applkatlons should ...

  11. U.S. EPA, Pesticide Product Label, , 05/08/1989

    EPA Pesticide Factsheets

    2011-04-21

    ... "'hare po •• 1bl •. ... ":" •• S 5?:-!:e":" n .. a=~. ;a:: .. r~~a .~~ ~. r, c~a:-g .. ra. ... Cont.et :rour !tate 'aatlelde or I:nel ron.ent.l Con:ro~ A9an:::T or Ha ...

  12. Aerial photo SBVC1962". Photo no. 360. Low oblique aerial view ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Aerial photo -SBVC-1962". Photo no. 360. Low oblique aerial view of the campus, looking southeast. Stamped on the rear: "Ron Wilhite, Sun-Telegram photo, file, 10/22/62/ - San Bernardino Valley College, 701 South Mount Vernon Avenue, San Bernardino, San Bernardino County, CA

  13. View of Expedition 28 Crew Members giving and receiving a haircut in the Node 3

    NASA Image and Video Library

    2011-07-31

    ISS028-E-019487 (31 July 2011) --- NASA astronaut Ron Garan, Expedition 28 flight engineer, trims astronaut Mike Fossum?s hair in the Tranquility node of the International Space Station. Garan used hair clippers fashioned with a vacuum device to garner freshly cut hair.

  14. Final Report of the KAPSE (Kernal Ada Programming Support Environment) Interface Team (KIT)

    DTIC Science & Technology

    1988-10-15

    Corporation Hans Mumm Naval Ocean Systems Center Bob Munck MITRE Margaret Murray Compusec Gil Myers Naval Ocean Systems Center LCDR Philip Myers NAVELEX-812...Data Corporation Steve Huseth Honeywell Ron Johnson Boeing Aerospace Corporation Mike Kamrad Honeywell , Reed Kotler Lockheed Missile and Space Pekka

  15. A&M. Hot liquid waste treatment building (TAN616). Camera facing north. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    A&M. Hot liquid waste treatment building (TAN-616). Camera facing north. Detail of personnel entrance door, stoop, and stairway. Photographer: Ron Paarmann. Date: September 22, 1997. INEEL negative no. HD-20-2-1 - Idaho National Engineering Laboratory, Test Area North, Scoville, Butte County, ID

  16. Rapid bedrock uplift in the Antarctic Peninsula explained by viscoelastic response to recent ice unloading

    NASA Astrophysics Data System (ADS)

    Nield, Grace A.; Barletta, Valentina R.; Bordoni, Andrea; King, Matt A.; Whitehouse, Pippa L.; Clarke, Peter J.; Domack, Eugene; Scambos, Ted A.; Berthier, Etienne

    2014-07-01

    Since 1995 several ice shelves in the Northern Antarctic Peninsula have collapsed and triggered ice-mass unloading, invoking a solid Earth response that has been recorded at continuous GPS (cGPS) stations. A previous attempt to model the observation of rapid uplift following the 2002 breakup of Larsen B Ice Shelf was limited by incomplete knowledge of the pattern of ice unloading and possibly the assumption of an elastic-only mechanism. We make use of a new high resolution dataset of ice elevation change that captures ice-mass loss north of 66°S to first show that non-linear uplift of the Palmer cGPS station since 2002 cannot be explained by elastic deformation alone. We apply a viscoelastic model with linear Maxwell rheology to predict uplift since 1995 and test the fit to the Palmer cGPS time series, finding a well constrained upper mantle viscosity but less sensitivity to lithospheric thickness. We further constrain the best fitting Earth model by including six cGPS stations deployed after 2009 (the LARISSA network), with vertical velocities in the range 1.7 to 14.9 mm/yr. This results in a best fitting Earth model with lithospheric thickness of 100-140 km and upper mantle viscosity of 6×1017-2×1018 Pa s - much lower than previously suggested for this region. Combining the LARISSA time series with the Palmer cGPS time series offers a rare opportunity to study the time-evolution of the low-viscosity solid Earth response to a well-captured ice unloading event.

  17. A Comparison of Ulnar Shortening Osteotomy Alone Versus Combined Arthroscopic Triangular Fibrocartilage Complex Debridement and Ulnar Shortening Osteotomy for Ulnar Impaction Syndrome

    PubMed Central

    Song, Hyun Seok

    2011-01-01

    Background This study compared the results of patients treated for ulnar impaction syndrome using an ulnar shortening osteotomy (USO) alone with those treated with combined arthroscopic debridement and USO. Methods The results of 27 wrists were reviewed retrospectively. They were divided into three groups: group A (USO alone, 10 cases), group B (combined arthroscopic debridement and USO, 9 cases), and group C (arthroscopic triangular fibrocartilage complex [TFCC] debridement alone, 8 cases). The wrist function was evaluated using the modified Mayo wrist score, disabilities of the arm, shoulder and hand (DASH) score and Chun and Palmer grading system. Results The modified Mayo wrist score in groups A, B, and C was 74.5 ± 8.9, 73.9 ± 11.6, and 61.3 ± 10.2, respectively (p < 0.05). The DASH score in groups A, B, and C was 15.6 ± 11.8, 19.3 ± 11.9, and 33.2 ± 8.5, respectively (p < 0.05). The average Chun and Palmer grading score in groups A and B was 85.7 ± 8.9 and 84.7 ± 6.7, respectively. The difference in the Mayo wrist score, DASH score and Chun and Palmer grading score between group A and B was not significant (p > 0.05). Conclusions Both USO alone and combined arthroscopic TFCC debridement with USO improved the wrist function and reduced the level of pain in the patients treated for ulnar impaction syndrome. USO alone may be the preferred method of treatment in patients if the torn flap of TFCC is not unstable. PMID:21909465

  18. Evaluating the Utility of Remotely-Sensed Soil Moisture Retrievals for Operational Agricultural Drought Monitoring

    NASA Technical Reports Server (NTRS)

    Bolten, John D.; Crow, Wade T.; Zhan, Xiwu; Jackson, Thomas J.; Reynolds,Curt

    2010-01-01

    Soil moisture is a fundamental data source used by the United States Department of Agriculture (USDA) International Production Assessment Division (IPAD) to monitor crop growth stage and condition and subsequently, globally forecast agricultural yields. Currently, the USDA IPAD estimates surface and root-zone soil moisture using a two-layer modified Palmer soil moisture model forced by global precipitation and temperature measurements. However, this approach suffers from well-known errors arising from uncertainty in model forcing data and highly simplified model physics. Here we attempt to correct for these errors by designing and applying an Ensemble Kalman filter (EnKF) data assimilation system to integrate surface soil moisture retrievals from the NASA Advanced Microwave Scanning Radiometer (AMSR-E) into the USDA modified Palmer soil moisture model. An assessment of soil moisture analysis products produced from this assimilation has been completed for a five-year (2002 to 2007) period over the North American continent between 23degN - 50degN and 128degW - 65degW. In particular, a data denial experimental approach is utilized to isolate the added utility of integrating remotely-sensed soil moisture by comparing EnKF soil moisture results obtained using (relatively) low-quality precipitation products obtained from real-time satellite imagery to baseline Palmer model runs forced with higher quality rainfall. An analysis of root-zone anomalies for each model simulation suggests that the assimilation of AMSR-E surface soil moisture retrievals can add significant value to USDA root-zone predictions derived from real-time satellite precipitation products.

  19. IMPACTS OF CLIMATE VARIATION AND CHANGE ON MID-ATLANTIC REGION HYDROLOGY

    EPA Science Inventory

    This study analyzes periodic variations in the climate of the mid-Atlantic Region over the last 100 years and uses general circulation models (GCMs) to project major climate trends for the next hundred years. Historical data include the Palmer Drought Severity Index (PDSI) for th...

  20. IFLA General Conference, 1986. Management and Technology Division. Section: Management of Library Associations (RT). Papers.

    ERIC Educational Resources Information Center

    International Federation of Library Associations and Institutions, The Hague (Netherlands).

    Papers presented at a session on management of library associations at the 1986 International Federation of Library Associations (IFLA) conference include: (1) "Medical Library Association: Organizational Change 1898 to Present--Illustrations from Continuing Education" (Raymond A. Palmer and M. Kent Mayfield, United States); (2)…

  1. Characterizing changes in drought risk for the United States from climate change

    EPA Science Inventory

    The effect of climate change on the frequency and intensity of droughts across the contiguous United States over the next century is assessed by applying Standardized Precipitation Indices and the Palmer Drought Severity Index to the full suite of 22 Intergovernmental Panel on Cl...

  2. Improving Germination of Nuttall Oak Acorns

    Treesearch

    R. L. Johnson

    1967-01-01

    Under simulated field conditions the best treatment for germination of acorns of Quercus nuttallii Palmer was a combination of sowing 1 inch below soil surface, under litter, and in partial shade. Supplemental watering was also advantageous. The most important factor was depth of sowing.

  3. Language Teachers' Target Language Project: Language for Specific Purposes of Language Teaching

    ERIC Educational Resources Information Center

    Korenev, Alexey; Westbrook, Carolyn; Merry, Yvonne; Ershova, Tatiana

    2016-01-01

    The Language Teachers' Target Language project (LTTL) aims to describe language teachers' target language use domain (Bachman & Palmer 2010) and to develop a language test for future teachers of English. The team comprises four researchers from Moscow State University (MSU) and Southampton Solent University.

  4. History of the Pacific Ocean Division Corps of Engineers 1957-1967

    DTIC Science & Technology

    1972-01-01

    mound barrier; designed by HED civil engineer Robert Q. Palmer, these concrete three-bar struc- tures provided a sturdy substitute for scarce rock...that metal buildings would require high main- tenance costs, while the termite problem eliminates construction in wood. Not only for these reasons

  5. The "Motherese" of Mr. Rogers: A Description of the Dialogue of Educational Television Programs.

    ERIC Educational Resources Information Center

    Rice, Mabel L.; Haight, Patti L.

    Dialogue from 30-minute samples from "Sesame Street" and "Mr. Rogers' Neighborhood" was coded for grammar, content, and discourse. Grammatical analysis used the LINGQUEST computer-assisted language assessment program (Mordecai, Palen, and Palmer 1982). Content coding was based on categories developed by Rice (1984) and…

  6. Photosynthetic Light Response of Bottomland Oak Seedlings Raised Under Partial Sunlight

    Treesearch

    Emile S. Gardiner

    2002-01-01

    Seedlings of cherrybark oak (Quercus pagoda Rafinesque), Nuttall oak (Quercus nuttallii Palmer) and overcup oak (Quercus lyrata Walter) were grown under two light levels, partial (20 percent) or full sunlight, to study physiological acclimation of leaves to low light availability. Shifts in leaf morphology were...

  7. The Importance of Character Development: An Interview with Ron Kinnamon.

    ERIC Educational Resources Information Center

    Kinnamon, Ron

    2003-01-01

    Building good character in today's youth is an adult issue because children learn values from adults. Adults must demonstrate the core values: trustworthiness, respect, responsibility, fairness, caring, and citizenship. Camps have developed expertise in character development and can provide leadership in the community in character education.…

  8. 2015 Inverter Workshop | Photovoltaic Research | NREL

    Science.gov Websites

    Utility PV Inverters-Ron Vidano, Advanced Energy Module Level Power Electronics-Jack Flicker (Chair ), Sandia National Laboratories Standardization and Reliability Testing of Module-Level Power Electronics Failure Modes in Inverters-Diganta Das, CALCE Corrosion of Electronics-Rob Sorensen, Sandia National

  9. Expedition 27 Docking

    NASA Image and Video Library

    2011-04-06

    Russian Mission Control Center is seen on Thursday, April 7, 2011 in Korolev, Russia. The Soyuz TMA-21 docked to the International Space Station carrying Expedition 27 Soyuz Commander Alexander Samokutyaev, NASA Flight Engineer Ron Garan and Russian Flight Engineer Andrey Borisenko. Photo Credit: (NASA/Carla Cioffi)

  10. Fossum and Garan in Node 2

    NASA Image and Video Library

    2008-06-07

    S124-E-007652 (7 June 2008) --- Astronauts Mike Fossum (foreground) and Ron Garan, both mission specialists, are busy in the Harmony node on the eve of STS-124's third and final session of extravehicular activity (EVA) to perform work on the International Space Station.

  11. Stennis historical marker

    NASA Image and Video Library

    2011-10-25

    Stennis Space Center Director Patrick Scheuermann (second from left) stands at the historical marker erected by the state of Mississippi in honor of the 50th anniversary of the NASA facility. Joining Scheuermann are: (l to r) Ron Magee, Al Watkins, Tish Williams and Ken P'Pool.

  12. QuEChERS, a sample preparation technique that is “catching on”: an up-to-date interview with its inventors

    USDA-ARS?s Scientific Manuscript database

    The technique of QuEChERS (Quick, Easy, Cheap, Effective, Rugged and Safe) is only 7 years old, yet it is revolutionizing the manner in which multiresidue, multiclass pesticide analysis (and perhaps beyond) is performed. Columnist Ron Majors sits down with inventors Steve Lehotay and Michelangelo An...

  13. Edinburgh Working Papers in Applied Linguistics, 1998.

    ERIC Educational Resources Information Center

    Parkinson, Brian, Ed.

    1998-01-01

    Papers on applied linguistics and language pedagogy include: "Non-Exact Quantification in Slide Presentations of Medical Research" (Ron Howard); "Modality and Point of View: A Contrastive Analysis of Japanese Wartime and Peacetime Newspaper Discourse" (Noriko Iwamoto); "Classroom Transcripts and 'Noticing' in Teacher Education" (Tony Lynch);…

  14. 76 FR 20624 - Central Montana Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-13

    ... will meet in Stanford, Montana. The committee is meeting as authorized under the Secure Rural Schools... Ranger District, located at 109 Central Avenue, Stanford, MT. Written comments should be sent to Ron Wiseman, Lewis and Clark National Forest, 109 Central Avenue, Stanford, Montana 59479. Comments may also...

  15. 76 FR 49433 - Central Montana Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-10

    ... will meet in Stanford, Montana. The committee is meeting as authorized under the Secure Rural Schools... Ranger District, located at 109 Central Avenue, Stanford, MT. Written comments should be sent to Ron Wiseman, Lewis and Clark National Forest, 109 Central Avenue, Stanford, Montana 59479. Comments may also...

  16. Review Symposium.

    ERIC Educational Resources Information Center

    Dennison, Bill; Fitz, John; Lauder, Hugh; Walford, Geoffrey; West, Anne

    1999-01-01

    Five reviewers of "School Choice and Competition: Markets in the Public Interest?" (Routledge, 1998), by Philip Woods, Carl Bagley, and Ron Glatter, critique this comprehensive study of three educational quasi-markets in Great Britain. Areas such as social stratification, overall student achievement, diversity, and innovation appear to…

  17. 77 FR 37001 - Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-20

    ... of the Interoperability Services Layer, Attn: Ron Chen, 400 Gigling Road, Seaside, CA 93955. Title; Associated Form; and OMB Number: Interoperability Services Layer; OMB Control Number 0704-TBD. Needs and Uses... INFORMATION: Summary of Information Collection IoLS (Interoperability Layer Services) is an application in a...

  18. Kernel Ada Programming Support Environment (KAPSE) Interface Team. Public Report. Volume 3.

    DTIC Science & Technology

    1983-10-25

    NWC MYERS, Gil NOSC MYERS, Philip NAVELEX NELSON, Eldred TRW OBERNDORF, Tricia NOSC P E, Shirley FCDSSA 2A-10 PURRIER, Lee FCDSSA OTB ROBERTSON...Sciences Corp. GRIESHEIMER, Eric McDonnel Douglas Astronautics JOHNSON, Ron Boeing Aerospace Co. KERNER, Judy Norden Systems KOTLER , Reed Lockheed Missiles

  19. 75 FR 4269 - Establishment of Class E Airspace; Lewisport, KY

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-27

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 [Docket No. FAA-2009-0706; Airspace Docket No. 09-ASO-26] Establishment of Class E Airspace; Lewisport, KY AGENCY: Federal... September 14, 2009 that establishes Class E Airspace at Hancock Co.--Ron Lewis Field, Lewisport, KY. DATES...

  20. Debate on the Draft--Helping Students Decide Where They Stand.

    ERIC Educational Resources Information Center

    Victory, James

    1981-01-01

    Presents four exercises to help secondary school social studies students understand the complex issues of the draft. Students participate in a mock draft lottery, analyze Phil Och's Draft Dodger Rag, examine how individual experiences affect attitudes, and compare writings by Bill Mauldin and Ron Kovic. (KC)

  1. 75 FR 12492 - Departmental Management; Public Meeting on BioPreferredSM

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-16

    ...; Public Meeting on BioPreferred\\SM\\ Intermediate Material and Feedstock Product Designation AGENCY... after registering. FOR FURTHER INFORMATION CONTACT: Ron Buckhalt, BioPreferred Manager, U.S. Department... program together as the BioPreferred\\SM\\ Program. Due to the changes mandated by the 2008 Farm Bill, and...

  2. A&M. Hot liquid waste treatment building (TAN616). Camera facing northeast. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    A&M. Hot liquid waste treatment building (TAN-616). Camera facing northeast. South wall with oblique views of west sides of structure. Photographer: Ron Paarmann. Date: September 22, 1997. INEEL negative no. HD-20-1-2 - Idaho National Engineering Laboratory, Test Area North, Scoville, Butte County, ID

  3. Incorporation of diet information derived from Bayesian stable isotope mixing models into mass-balanced marine ecosystem models: A case study from the Marennes-Oleron Estuary, France

    EPA Science Inventory

    We investigated the use of output from Bayesian stable isotope mixing models as constraints for a linear inverse food web model of a temperate intertidal seagrass system in the Marennes-Oléron Bay, France. Linear inverse modeling (LIM) is a technique that estimates a complete net...

  4. 77 FR 76494 - Changes in Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-28

    ..., Suite 11, Downieville, CA 95936. Colorado: Arapahoe (FEMA Docket No.: B- City of Centennial The... Authority, 76 of Centennial, Inverness Drive East, 13133 East Arapahoe Suite A, Centennial, CO Road, Centennial, 80112. CO 80112. Arapahoe (FEMA Docket No.: B- City of Greenwood The Honorable Ron City Hall...

  5. The study on the application of low polymerization degree PODE2

    NASA Astrophysics Data System (ADS)

    Xue, Zhenzhen; Shang, Hongyan; Zhang, Zailong; Cui, Chuntao; Zhao, Shidong

    2017-05-01

    Polyoxymethylene dimethyl ethers (PODEn) are a kind of excellent diesel blending components. Due to the low flash point of PODE2, it is not appropriate to be used as diesel blending component, so in this paper, the application of PODE2 have been studied. It seems that PODE2 is a kind of excellent green rubber solvent oil without sulfur and aromatic. Moreover, the application of PODE2 as gasoline blending component is investigated and it is found that the Research Octane Number(RON) of gasoline product and the RON of four different gasoline components(including hydrofining gasoline, hydrocracking light naphtha, catalytic reforming gasoline and mixed gasoline with 80vol% hydrofining gasoline and 20vol% catalytic reforming gasoline) is all slightly decreased to some extent respectively, which indicates that there is no apparently synergistic effect between PODE2 and the gasoline components, but PODE2 can effectively reduce the sulfur content, olefin content, aromatic content and can suppress the vapor pressure of gasoline.

  6. Design of high breakdown voltage vertical GaN p-n diodes with high-K/low-K compound dielectric structure for power electronics applications

    NASA Astrophysics Data System (ADS)

    Du, Jiangfeng; Li, Zhenchao; Liu, Dong; Bai, Zhiyuan; Liu, Yang; Yu, Qi

    2017-11-01

    In this work, a vertical GaN p-n diode with a high-K/low-K compound dielectric structure (GaN CD-VGD) is proposed and designed to achieve a record high breakdown voltage (BV) with a low specific on-resistance (Ron,sp). By introducing compound dielectric structure, the electric field near the p-n junction interface is suppressed due to the effects of high-K passivation layer, and a new electric field peak is induced into the n-type drift region, because of a discontinuity of electrical field at the interface of high-K and low-K layer. Therefore the distribution of electric field in GaN p-n diode becomes more uniform and an enhancement of breakdown voltage can be achieved. Numerical simulations demonstrate that GaN CD-VGD with a BV of 10650 V and a Ron,sp of 14.3 mΩ cm2, resulting in a record high figure-of-merit of 8 GW/cm2.

  7. Cosmic rays and the magnetic field in the nearby starburst galaxy NGC 253

    NASA Astrophysics Data System (ADS)

    Heesen, Volker

    2008-02-01

    The transport of cosmic rays (CR's) in large-scale magnetic fields can be bes t investigated in edge-on galaxies with radio continuum observations including p olarization. I observed the nearby starburst galaxy NGC 253 which hosts one of t he brightest known radio halos with the Effelsberg 100-m telescope and the VLA i nterferometer. The vertical emission profiles follow closely a two-component exp onential distribution where the scaleheight is a linear function of the synchrot ron lifetime of the CR electrons. This requires a convection dominated CR transp ort from the disk into the halo while the CR's lose their energy due to synchrot ron radiation the so-called CR aging. The interaction of the "disk-wind" with th e magnetic field explains the "X"-shaped magnetic field structure centered on th e nucleus where the ordered magnetic field is amplified by compression in the bo undaries of the expanding superbubbles of hot gas.

  8. Preventing distraction: Assessing stimulus-specific and general effects of the predictive cueing of deviant auditory events

    PubMed Central

    Horváth, János; Sussman, Elyse; Winkler, István; Schröger, Erich

    2011-01-01

    Rare irregular sounds (deviants) embedded into a regular sound sequence have large potential to draw attention to themselves (distraction). It has been previously shown that distraction, as manifested by behavioral response delay, and the P3a and reorienting negativity (RON) event-related potentials, could be reduced when the forthcoming deviant was signaled by visual cues preceding the sounds. In the present study, we investigated the type of information used in the prevention of distraction by manipulating the information content of the visual cues preceding the sounds. Cues could signal the specific variant of the forthcoming deviant, or they could just signal that the next tone was a deviant. We found that stimulus-specific cue information was used in reducing distraction. The results also suggest that early P3a and RON index processes related to the specific deviating stimulus feature, whereas late P3a reflects a general distraction-related process. PMID:21310210

  9. From physical inactivity to immobilization: Dissecting the role of oxidative stress in skeletal muscle insulin resistance and atrophy.

    PubMed

    Pierre, Nicolas; Appriou, Zephyra; Gratas-Delamarche, Arlette; Derbré, Frédéric

    2016-09-01

    In the literature, the terms physical inactivity and immobilization are largely used as synonyms. The present review emphasizes the need to establish a clear distinction between these two situations. Physical inactivity is a behavior characterized by a lack of physical activity, whereas immobilization is a deprivation of movement for medical purpose. In agreement with these definitions, appropriate models exist to study either physical inactivity or immobilization, leading thereby to distinct conclusions. In this review, we examine the involvement of oxidative stress in skeletal muscle insulin resistance and atrophy induced by, respectively, physical inactivity and immobilization. A large body of evidence demonstrates that immobilization-induced atrophy depends on the chronic overproduction of reactive oxygen and nitrogen species (RONS). On the other hand, the involvement of RONS in physical inactivity-induced insulin resistance has not been investigated. This observation outlines the need to elucidate the mechanism by which physical inactivity promotes insulin resistance. Copyright © 2015 Elsevier Inc. All rights reserved.

  10. Reflexive Pedagogy: Disciplinary Idioms as Resources for Teaching

    ERIC Educational Resources Information Center

    Garnett, Robert F.; Vanderlinden, Lisa K.

    2011-01-01

    Disciplinary models of learning such as ethnography (cultural anthropology) and market competition (economics) have received little attention in the burgeoning literature on "how teacher thinking shapes education". To mobilize the pedagogical potential of these disciplinary idioms, the authors draw from the path-breaking works of Palmer and…

  11. EFFECTS OF DIBUTYL PHTHALATE IN MALE RABBITS FOLLOWING IN UTERO, ADOLESCENT OR POST-PUBERTAL EXPOSURE

    EPA Science Inventory

    Effects of dibutyl phthalate in male rabbits following in utero, adolescent, or post-pubertal exposure
    Ty T. Higuchi1, Jennifer S. Palmer1, L. Earl Gray Jr2., and D. N. Rao Veeramachaneni1
    1Animal Reproduction and Biotechnology Laboratory, Colorado State University, Fort

  12. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (74th, Boston, Massachusetts, August 7-10, 1991). Part XVI: Miscellaneous Studies, Section A.

    ERIC Educational Resources Information Center

    Association for Education in Journalism and Mass Communication.

    Section A of the Miscellaneous Studies section of the proceedings contains the following 17 papers: "Readability Reconsidered: A Study of Reader Reactions to Differences in Fog Indexes" (Katherine C. McAdams); "Country and Nostalgia: Space and Time in Magazine Journalism" (Allen W. Palmer); "Images and Descriptions: A…

  13. Forum: Communication Activism Pedagogy. Beyond the Charity-Service Paradigm: Building Ethical Platforms for Social Justice Education with Those Most Affected

    ERIC Educational Resources Information Center

    Badger, L. N.

    2017-01-01

    In this forum response essay, the author proposes that the largest challenge "and" benefit of Communication Activism Pedagogy (CAP) is bound up in a small but significant word in Frey and Palmer's (2014) definition of Communication Activism Pedagogy: "with." Working "with oppressed community members" challenges the…

  14. Forum: Communication Activism Pedagogy. Turning Communication Activism Pedagogy Teaching into Communication Activism Pedagogy Research

    ERIC Educational Resources Information Center

    Frey, Lawrence R.; Palmer, David L.

    2017-01-01

    In this rejoinder to this forum's respondents to the stimulus essay, "Communication Activism Pedagogy and Research: Communication Education Scholarship to Promote Social Justice," Lawrence Frey and David Palmer state that the forum editors asked them and the invited respondents to focus on communication activism pedagogy (CAP) research…

  15. Reducing Apprehensions of Adolescent Singers in Choral Classrooms

    ERIC Educational Resources Information Center

    Silvey, Philip E.

    2014-01-01

    Choral music educators can purposefully create a learning environment that helps minimize the anxieties of young singers. According to Parker Palmer, "to teach is to create a space" that possesses three qualities: hospitality, openness, and boundaries. Choral music educators can influence these characteristics by applying five strategies…

  16. Winter cover crops influence Amaranthus palmeri establishment

    USDA-ARS?s Scientific Manuscript database

    Winter cover crops were evaluated for their effect on Palmer amaranth (PA) suppression in cotton production. Cover crops examined included rye and four winter legumes: narrow-leaf lupine, crimson clover, Austrian winter pea, and cahaba vetch. Each legume was evaluated alone and in a mixture with rye...

  17. Satellite assessment of early-season forecasts for vegetation conditions of grazing allotments in Nevada, United States

    USDA-ARS?s Scientific Manuscript database

    Fifteen years of enhanced vegetation index data from the MODIS sensor are examined in conjunction with precipitation and the Palmer drought severity index to assess how well growing season conditions for vegetation within grazing allotments of Nevada can be predicted at different times of the year. ...

  18. Frost Heaving of Container Hardwood Seedlings Planted in an Abandoned Agriculitural Field in Sharkey County, Mississippi

    Treesearch

    Matthew C. Stroupe; Hans M. Williams

    1999-01-01

    The use of container hardwood seedlings is an alternative to bareroot planting stock. In January 1996, 1,485 container seedlings of Nuttall oak (Quercus nuttallii Palmer), willow oak (Q. phellos L.). overcup oak (Q. lyrata Walter), and water oak (Q. nigra L.) were planted in Sharkey clay...

  19. 76 FR 69793 - Qualification of Drivers; Exemption Applications; Vision

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-09

    ... Carlos R. Gonzalez Jerard David Menyhart Danny Michael Harris Kevin Palmer Moises P. Ibarra Jeffery O... Roscoe Brittain III Jerry M. Puckett Larry Dexter Georgia Marcum John Darr Kevin Menard Christopher Jax Charles Ray Brittain Kevin Robert Cowger Clifford Blaine Thompson Timothy Garland Kevin Barker The...

  20. Forum: Communication Activism Pedagogy. A Call for an Ethic of Transformation in Communication Activism Education

    ERIC Educational Resources Information Center

    Artz, Lee

    2017-01-01

    Lawrence Frey and David Palmer present a provocative call for communication education and research that is urgent and opportune in this forum's stimulus essay, "Communication Activism Pedagogy and Research: Communication Education Scholarship to Promote Social Justice." The call is urgent because the global human condition--including…

  1. A Model for Statewide Evaluation of a Universal Positive Behavior Support Initiative

    ERIC Educational Resources Information Center

    Elfner Childs, Karen; Kincaid, Don; George, Heather Peshak

    2010-01-01

    Several statewide evaluations of Tier 1/Universal Level Positive Behavior Support (PBS) implementation efforts have been conducted, adhering to the evaluation template developed by Horner, Sugai, and Lewis-Palmer in 2005. Building on these examples, Florida's Positive Behavior Support Project developed a comprehensive evaluation system that sought…

  2. Requirements Engineering and Analysis Workshop Proceedings Held in Pittsburgh, Pennsylvania on 12-14 March 1991

    DTIC Science & Technology

    1991-12-01

    urally. 6.5 Summary of Current or Potential Approaches Many approaches to context analysis were discussed by the group, including: * Causal Trees * SWOT ... Apple Computer, 1988 1 Aseltine, J., Beam, W.R., Palmer, J.D., Sage, A.P., 1989, Introduction To Computer Systems: Analysis, Design and Application

  3. 78 FR 21628 - Notice of Dominguez-Escalante National Conservation Area Advisory Council Meeting Cancellation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-11

    ... Dominguez-Escalante National Conservation Area Advisory Council Meeting Cancellation and Change of Location... Meeting Change of Location. SUMMARY: In accordance with the Federal Land Policy and Management Act (FLPMA... Courthouse, Room 234, 501 Palmer Street, Delta, CO, has been cancelled. The location of a subsequent meeting...

  4. Friction in Sliding Orthodontic Mechanics: Ceramic Brackets, Teflon-Coated Wires and Comparative Resistances

    DTIC Science & Technology

    1989-01-01

    Nitinol ; Unitek Corp., Monrovia, CA.) against the 3 bracket-slot. With increased angulation, however, the Nitinol wire created much less friction than...Palmer, F.: Friction, Sci. Am. 184:54-58, 1951. Petersen, L., Spencer, R., and Andreasen, G.: A com- parison of friction resistance for Nitinol and

  5. Nonlocal theory of beam-driven electron Bernstein waves

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jain, V.K.; Tripathi, V.K.

    A nonlocal theory of electron Bernstein waves driven unstable by an axial beam (V = V/sub b/z-italic-circumflex) of finite width has been developed. Assuming a parabolic density profile for the background plasma, an equation describing the mode structure of the wave is obtained in the slab geometry. The eigenfunctions are found to be Hermite polynomials. Expressions for the growth rates of the instabilities caused by Cerenkov and slow cyclotron interactions are derived. The results of the theory are applied to explain some of the experimental observations of Jain and Christiansen (Phys. Lett. A 82, 127 (1981)).

  6. On Vaccination & Chiropractic: when ideology, history, perception, politics and jurisprudence collide.

    PubMed

    Gleberzon, Brian; Lameris, Marlee; Schmidt, Catherine; Ogrady, Jillian

    2013-09-01

    The Palmers espoused anti-vaccination opinions in the early part of the 20(th) century, rejecting the germ theory of disease in favor of a worldview that a subluxation-free spine, achieved by spinal adjustments, would result in an unfettered innate intelligence; this, along with other healthful lifestyle choices, would allow a person to thwart disease by marshaling the body's natural recuperative abilities. Some chiropractors continue to staunchly champion the Palmer postulates, while others do not. At the national level, advocacy organizations publish conflicting position statements. We explore how this divisiveness has impacted chiropractic ideology, perceptions among students and practitioners, politics and issues of jurisprudence as reflected by the evolution of a standard of chiropractic practice in at least one Canadian province (Ontario). We opine that the chiropractic profession should champion a health promotion and disease prevention approach to vaccination, which would allow it to align itself with the broader healthcare community while not abandoning its traditional tenets.

  7. Academic Futures: Prospects for Post-Secondary Education.

    ERIC Educational Resources Information Center

    Shere, Waris, Ed.; Duhamel, Ronald, Ed.

    Present trends and future directions in postsecondary education in Canada and the United States are addressed in 15 essays and an introduction by Ron Duhamel. Authors and titles are as follows: "Traditional Values in the Contemporary University" (Robin H. Farquhar); "Facing the Future" (R. J. Duhamel); "Challenges to the…

  8. Trends in Education Philanthropy: A Roundtable with Foundation Leaders

    ERIC Educational Resources Information Center

    Connection: The Journal of the New England Board of Higher Education, 2006

    2006-01-01

    In February 2006, Nellie Mae Education Foundation President and Chief Executive Officer Blenda J. Wilson convened a roundtable discussion on trends in education philanthropy. Wilson's guests were Ron Ancrum, president of Associated Grant Makers, which serves grantmaking members in Massachusetts and New Hampshire; Nancy P. Roberts, president of the…

  9. U.S. EPA, Pesticide Product Label, , 01/06/1983

    EPA Pesticide Factsheets

    2011-04-21

    ... nO ron! ... I. ' ... r .htr r .. ~t'oI-dn~ lilt" Ht:T~S.-\\~ ttt"'lfti ... O-\\:;:I&If' r .. M'....L~ to-_'nt"r Il':.n" mOfllh, al\\o;-r lit 1 \\---\\ i'I'." Ill.· n 'I'l.i~ r~ ... df'r .. d ..... j (hare-, .. ...

  10. Assessment of Attack Reconnaissance Helicopter (ARH) Machining, Cutting and Drilling Operations

    DTIC Science & Technology

    2006-09-29

    Date: June 20, 2006 Name Organization Email Jim Corwin Consultant JCAI/Army corwinj@att.net Cindy Fenny Process Engineer Bell / Process Engineering...bellhelicopter.textron.com Cindy Fenny Process Eng 817-280-2549 cfenny@bellhelicopter.textron.com Max Trull Process Eng 817-280-2678 mtrull@bellhelicopter.textron.com Ron

  11. The Navy Supply Corps Newsletter. Contracting Innovations: Navy Electronic Commerce Online Navy Afloat Purchase Card Program. Volume 62, No. 3.

    DTIC Science & Technology

    1998-06-01

    Mike Lyden John Lantelme Andy Mackel Jesus Malgapo Carol Marcinek Greg Martin Michelle McAtee Molly McClellan Jerry McEnerney Laurie McKee...Paul McNeill Walt Melton Rich Mendez Mike Metts Jon Miller Ron Mosley Jim Naber Craig Nostrant NAVSUP USSNORMANDY(CG60) DDRE NORFOLK NPGS

  12. Health Care for the Homeless. Hearing before the Subcommittee on Health and the Environment of the Committee on Energy and Commerce. House of Representatives, Ninety-Ninth Congress, Second Session (December 15, 1986).

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Committee on Energy and Commerce.

    This document presents witnesses' testimonies and related materials from the Congressional hearing called to consider how the federal government can better meet the health needs of the homeless. Opening statements are included from Congressmen Henry Waxman, Ron Wyden, and Gerry Sikorski. Witnesses providing testimony include Robert Gallagher and…

  13. How does service drive the service company?

    PubMed

    Quinlan, M R; Zemke, R; Snider, J; Nemeroff, D; Reinemund, S S; Ayling, R; Singh, K; Perkins, J A; Antonini, J E; Loeb, W F

    1991-01-01

    "How Does Service Drive the Service Company?" presents commentators on Leonard A. Schlesinger and James L. Heskett's September-October article. Commentators include Michael R. Quinlan, Ron Zemke, Jim Snider, Dinah Nemeroff, Steven S. Reinemund, Robert Ayling, Karmjit Singh, James A. Perkins, Joseph E. Antonini, and Walter F. Loeb.

  14. Garan works with MELFI in Kibo

    NASA Image and Video Library

    2011-04-13

    iss027e014283 (4/13/2011) --- Expedition 27 flight engineer Ron Garan prepares to stow a blood draw for the CSA (Canadian Space Agency) Vascular Blood Collection protocol in the Minus Eighty Laboratory Freezer for ISS (MELFI-1) in the Kibo laboratory of the International Space Station.

  15. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (80th, Chicago, Illinois, July 30-August 2, 1997): Media Management and Economics.

    ERIC Educational Resources Information Center

    Association for Education in Journalism and Mass Communication.

    The Media Management and Economics section of the Proceedings contains the following 14 papers: "The Case Method and Telecommunication Management Education: A Classroom Trial" (Anne Hoag, Ron Rizzuto, and Rex Martin); "It's a Small Publishing World after All: Media Monopolization of the Children's Book Market" (James L.…

  16. AIDS and Teenagers: Emerging Issues. Hearing before the Select Committee on Children, Youth, and Families. House of Representatives, One Hundredth Congress, First Session.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Select Committee on Children, Youth, and Families.

    This document presents testimonies from the Congressional hearing examining the Acquired Immunodeficiency Syndrome (AIDS) crisis and its impact on teenagers. Opening remarks from Representatives George Miller, Dan Coats, Ted Weiss, Ron Packard, and J. Roy Rowland stress the importance of determining how to protect adolescents from AIDS. C. Everett…

  17. 77 FR 61457 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Designation of Longer Period for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-09

    ... Physical Copper Trust Pursuant To NYSE Arca Equities Rule 8.201 October 2, 2012. On April 2, 2012, NYSE... Copper Trust (``Trust'') pursuant to NYSE Arca Equities Rule 8.201. The proposed rule change was..., Director of Purchasing, Encore Wire Corporation; Ron Beal, Executive Vice President, Tubes Division, Luvata...

  18. Panel discussion: Fumonisin Elimination. In: Proceedings of the Aflatoxin/Fumonisin Elimination and Fungal Genomics Workshops, October 22-24, 2007, Atlanta, Georgia

    USDA-ARS?s Scientific Manuscript database

    Summary of Presentations: The session was moderated by Scott Averhoff of the Texas Corn Producers Board. Ron Riley and Anthony Glenn from the USDA-ARS Toxicology & Mycotoxin Research Unit in Athens, GA presented a set of reports on the effects of fumonisin on corn seedling development and disease. F...

  19. Former Presidents Reflect on 20 Years of NCSSSMST

    ERIC Educational Resources Information Center

    Templin, Elizabeth, Comp.

    2008-01-01

    The Consortium celebrated its 20th anniversary at the 2008 Professional Conference in Dallas, Texas in February 2008. Founding president Stephanie Pace Marshall and former presidents Joan Barber, Janet Hugo, Ron Laugen, Cheryl Lindeman, Dennis Lundgren, and Betty Stapp responded to questions about the organization and their involvement with…

  20. Macintoshed Libraries 5. Fifth Edition.

    ERIC Educational Resources Information Center

    Valauskas, Edward J., Ed.; Vaccaro, Bill, Ed.

    This annual collection contains 16 papers about the use of Macintosh computers in libraries which include: "New Horizons in Library Training: Using HyperCard for Computer-Based Staff Training" (Pauline S. Bayne and Joe C. Rader); "Get a Closet!" (Ron Berntson); "Current Periodicals: Subject Access the Mac Way"…

  1. Responding to Fiscal Tensions and a Changing Educational Context: A Librarian Entrepreneur

    ERIC Educational Resources Information Center

    Willmott, Kristen E.; Wall, Andrew F.

    2012-01-01

    This case explores various entrepreneurial initiatives introduced by Dr. Ron Dow, dean of libraries, at a private, research-extensive institution in the northeastern United States. The case serves as an example of how entrepreneurial ideas can be applied within educational contexts, specifically, the academic support context of the university…

  2. 75 FR 5033 - Departmental Management; Public meeting on BioPreferredSM

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-01

    ...; Public meeting on BioPreferred\\SM\\ Complex Products and Assemblies Designation and Industry Training on... include: 1. Using BioPreferred tools to position your business to sell or increase sales to the Federal...: Ron Buckhalt, BioPreferred Manager, U.S. Department of Agriculture, Office of Procurement and Property...

  3. An Investigation of Methods for Reducing Sampling Error in Certain IRT (Item Response Theory) Procedures.

    DTIC Science & Technology

    1983-08-01

    34th Streets Lawrence, KS 66045 Baltimore, MD 21218 ENIC Facility-Acquisitions 1 Dr. Ron Hambleton 4t33 Rugby Avenue School of Education Lcthesda, !ID...Sector Dr. V. R. R. Uppuluri 1 Dr. Rand R. Wilcox Union Carbide Corporation University of Southern California Nuclear Division Department of

  4. 77 FR 75425 - Interagency Working Group on Plant Genomics (IWGPG): The National Plant Genome Initiative-What's...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-20

    ... Genome Initiative--What's Next? AGENCY: Office of Science, Office of Biological and Environmental... INFORMATION CONTACT: Dr. Catherine Ronning, U.S. Department of Energy, Office of Science, Office of Biological... 20585-1290. Phone 301-903-9549, fax (301) 903-5051, email: [email protected]science.doe.gov ; Dr. Jane...

  5. Exploring the Relationship Between Octane Sensitivity and Heat-of-Vaporization

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sluder, C. Scott; Szybist, James P.; McCormick, Robert L.

    2016-04-05

    The latent heat-of-vaporization (HoV) of blends of biofuel and hydrocarbon components into gasolines has recently experienced expanded interest because of the potential for increased HoV to increase fuel knock resistance in direct-injection (DI) engines. Several studies have been conducted, with some studies identifying an additional anti-knock benefit from HoV and others failing to arrive at the same conclusion. Consideration of these studies holistically shows that they can be grouped according to the level of fuel octane sensitivity variation within their fuel matrices. When comparing fuels of different octane sensitivity significant additional anti-knock benefits associated with HoV are sometimes observed. Studiesmore » that fix the octane sensitivity find that HoV does not produce additional anti-knock benefit. New studies were performed at ORNL and NREL to further investigate the relationship between HoV and octane sensitivity. Three fuels were formulated for the ORNL study with matched RON and octane sensitivity, but with differing HoV. Experiments with these fuels in a 1.6-liter GTDI engine showed that the fuels exhibited very similar combustion phasing under knock-limited spark advance (KLSA) conditions. Fuels having a range of RON, octane sensitivity, and HoV were tested at NREL in a single-cylinder GDI engine under conditions where octane sensitivity has little effect on knock resistance. KLSA was found to be well correlated with RON. These results reinforce the concept that HoV anti-knock effects can be viewed as a contributor to octane sensitivity. From this viewpoint, HoV effects manifest themselves as increases in octane sensitivity.« less

  6. Redox homeostasis and age‐related deficits in neuromuscular integrity and function

    PubMed Central

    Lightfoot, Adam P.; Earl, Kate E.; Stofanko, Martin; McDonagh, Brian

    2017-01-01

    Abstract Skeletal muscle is a major site of metabolic activity and is the most abundant tissue in the human body. Age‐related muscle atrophy (sarcopenia) and weakness, characterized by progressive loss of lean muscle mass and function, is a major contributor to morbidity and has a profound effect on the quality of life of older people. With a continuously growing older population (estimated 2 billion of people aged >60 by 2050), demand for medical and social care due to functional deficits, associated with neuromuscular ageing, will inevitably increase. Despite the importance of this ‘epidemic’ problem, the primary biochemical and molecular mechanisms underlying age‐related deficits in neuromuscular integrity and function have not been fully determined. Skeletal muscle generates reactive oxygen and nitrogen species (RONS) from a variety of subcellular sources, and age‐associated oxidative damage has been suggested to be a major factor contributing to the initiation and progression of muscle atrophy inherent with ageing. RONS can modulate a variety of intracellular signal transduction processes, and disruption of these events over time due to altered redox control has been proposed as an underlying mechanism of ageing. The role of oxidants in ageing has been extensively examined in different model organisms that have undergone genetic manipulations with inconsistent findings. Transgenic and knockout rodent studies have provided insight into the function of RONS regulatory systems in neuromuscular ageing. This review summarizes almost 30 years of research in the field of redox homeostasis and muscle ageing, providing a detailed discussion of the experimental approaches that have been undertaken in murine models to examine the role of redox regulation in age‐related muscle atrophy and weakness. PMID:28744984

  7. European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS).

    PubMed

    Egea, Javier; Fabregat, Isabel; Frapart, Yves M; Ghezzi, Pietro; Görlach, Agnes; Kietzmann, Thomas; Kubaichuk, Kateryna; Knaus, Ulla G; Lopez, Manuela G; Olaso-Gonzalez, Gloria; Petry, Andreas; Schulz, Rainer; Vina, Jose; Winyard, Paul; Abbas, Kahina; Ademowo, Opeyemi S; Afonso, Catarina B; Andreadou, Ioanna; Antelmann, Haike; Antunes, Fernando; Aslan, Mutay; Bachschmid, Markus M; Barbosa, Rui M; Belousov, Vsevolod; Berndt, Carsten; Bernlohr, David; Bertrán, Esther; Bindoli, Alberto; Bottari, Serge P; Brito, Paula M; Carrara, Guia; Casas, Ana I; Chatzi, Afroditi; Chondrogianni, Niki; Conrad, Marcus; Cooke, Marcus S; Costa, João G; Cuadrado, Antonio; My-Chan Dang, Pham; De Smet, Barbara; Debelec-Butuner, Bilge; Dias, Irundika H K; Dunn, Joe Dan; Edson, Amanda J; El Assar, Mariam; El-Benna, Jamel; Ferdinandy, Péter; Fernandes, Ana S; Fladmark, Kari E; Förstermann, Ulrich; Giniatullin, Rashid; Giricz, Zoltán; Görbe, Anikó; Griffiths, Helen; Hampl, Vaclav; Hanf, Alina; Herget, Jan; Hernansanz-Agustín, Pablo; Hillion, Melanie; Huang, Jingjing; Ilikay, Serap; Jansen-Dürr, Pidder; Jaquet, Vincent; Joles, Jaap A; Kalyanaraman, Balaraman; Kaminskyy, Danylo; Karbaschi, Mahsa; Kleanthous, Marina; Klotz, Lars-Oliver; Korac, Bato; Korkmaz, Kemal Sami; Koziel, Rafal; Kračun, Damir; Krause, Karl-Heinz; Křen, Vladimír; Krieg, Thomas; Laranjinha, João; Lazou, Antigone; Li, Huige; Martínez-Ruiz, Antonio; Matsui, Reiko; McBean, Gethin J; Meredith, Stuart P; Messens, Joris; Miguel, Verónica; Mikhed, Yuliya; Milisav, Irina; Milković, Lidija; Miranda-Vizuete, Antonio; Mojović, Miloš; Monsalve, María; Mouthuy, Pierre-Alexis; Mulvey, John; Münzel, Thomas; Muzykantov, Vladimir; Nguyen, Isabel T N; Oelze, Matthias; Oliveira, Nuno G; Palmeira, Carlos M; Papaevgeniou, Nikoletta; Pavićević, Aleksandra; Pedre, Brandán; Peyrot, Fabienne; Phylactides, Marios; Pircalabioru, Gratiela G; Pitt, Andrew R; Poulsen, Henrik E; Prieto, Ignacio; Rigobello, Maria Pia; Robledinos-Antón, Natalia; Rodríguez-Mañas, Leocadio; Rolo, Anabela P; Rousset, Francis; Ruskovska, Tatjana; Saraiva, Nuno; Sasson, Shlomo; Schröder, Katrin; Semen, Khrystyna; Seredenina, Tamara; Shakirzyanova, Anastasia; Smith, Geoffrey L; Soldati, Thierry; Sousa, Bebiana C; Spickett, Corinne M; Stancic, Ana; Stasia, Marie José; Steinbrenner, Holger; Stepanić, Višnja; Steven, Sebastian; Tokatlidis, Kostas; Tuncay, Erkan; Turan, Belma; Ursini, Fulvio; Vacek, Jan; Vajnerova, Olga; Valentová, Kateřina; Van Breusegem, Frank; Varisli, Lokman; Veal, Elizabeth A; Yalçın, A Suha; Yelisyeyeva, Olha; Žarković, Neven; Zatloukalová, Martina; Zielonka, Jacek; Touyz, Rhian M; Papapetropoulos, Andreas; Grune, Tilman; Lamas, Santiago; Schmidt, Harald H H W; Di Lisa, Fabio; Daiber, Andreas

    2017-10-01

    The European Cooperation in Science and Technology (COST) provides an ideal framework to establish multi-disciplinary research networks. COST Action BM1203 (EU-ROS) represents a consortium of researchers from different disciplines who are dedicated to providing new insights and tools for better understanding redox biology and medicine and, in the long run, to finding new therapeutic strategies to target dysregulated redox processes in various diseases. This report highlights the major achievements of EU-ROS as well as research updates and new perspectives arising from its members. The EU-ROS consortium comprised more than 140 active members who worked together for four years on the topics briefly described below. The formation of reactive oxygen and nitrogen species (RONS) is an established hallmark of our aerobic environment and metabolism but RONS also act as messengers via redox regulation of essential cellular processes. The fact that many diseases have been found to be associated with oxidative stress established the theory of oxidative stress as a trigger of diseases that can be corrected by antioxidant therapy. However, while experimental studies support this thesis, clinical studies still generate controversial results, due to complex pathophysiology of oxidative stress in humans. For future improvement of antioxidant therapy and better understanding of redox-associated disease progression detailed knowledge on the sources and targets of RONS formation and discrimination of their detrimental or beneficial roles is required. In order to advance this important area of biology and medicine, highly synergistic approaches combining a variety of diverse and contrasting disciplines are needed. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.

  8. An assessment of three measures of long-term moisture deficiency before critical fire periods.

    Treesearch

    Donald A. Haines; Von J. Johnson; William A. Main

    1976-01-01

    Values of the Palmer Drought Index, the Keetch-Byram Drought Index, and a Buildup Index are calculated for 26 critical fires situations in the north-central and north-eastern states. The paper examines the response characteristics of these indexes, representative of different moisture regimes, relative to fire danger.

  9. Forum: Communication Activism Pedagogy. Expanding CAP's Interventionist Model and Developing Proper Learning Rubrics

    ERIC Educational Resources Information Center

    Del Gandio, Jason

    2017-01-01

    For Frey and Palmer (2014), communication activism pedagogy (CAP) "teaches students how to use their communication knowledge and resources (e.g., theories, research methods, pedagogies, and other practices) to work with community members to intervene into and reconstruct unjust discourses in more just ways." The author of this response…

  10. Learning and Study Practices of Postsecondary American Indian/Alaska Native Students

    ERIC Educational Resources Information Center

    Aragon, Steven R.

    2004-01-01

    This study examined the learning and study practices of postsecondary American Indian/Alaska Native students attending community colleges in the southwest. Using a survey design, students completed the Kagan Matching Familiar Figures Test, the Schmeck, Ribich, and Ramanaiah Inventory of Learning Processes, and the Weinstein, Palmer, and Schulte…

  11. Recent Advances in High-Resolution MEMS DM Fabrication and Integration

    DTIC Science & Technology

    2010-09-01

    MOEMS , [8], 031308-031308, (2009). [2] Macintosh B, Graham J, Palmer D, Doyon R, Gavel D, Larkin J, Oppenheimer B, Saddlemyer L, Wallace JK, Bauman B... MOEMS , [8], 033040-033014, (2009). [6] Smith JC, Sanchez DJ, Oesch DW, Engstrom N, AgrguelloLoretta, Tewksbury-Christle CM, Vitayaudom KP, Kelly PR

  12. Idaho's Educator Landscape: How Is the State's Teacher Workforce Responding to Its Students' Needs?

    ERIC Educational Resources Information Center

    Hanson, Havala; Yoon, Sun Young

    2018-01-01

    Many school districts in the United States are facing severe teacher shortages (Bordonaro, 2017; Palmer, 2017; Seattle Pacific University, 2017; Whaley, 2017). In several states--including Idaho--the difficulty of hiring qualified candidates has expanded beyond historical high-need content areas such as special education and mathematics to include…

  13. New species of Braggia (Hemiptera: Aphididae) on buckwheat in western North America

    Treesearch

    K. S. Pike; G. Graf; R. G. Foottit; H. E. L. Maw; P. Stary; R. Hammon; D. G. Miller

    2009-01-01

    Species of Braggia Gillette and Palmer (Hemiptera: Aphididae: Aphidinae: Aphidini) feed on various buckwheat, Eriogonum Michx. (Polygonaceae), species in western North America. Two new species, Braggia columbiana Pike n. sp. from Washington and Oregon and Braggia longicauda Pike n. sp. from Washington, Oregon, and northern California, are proposed. Descriptions,...

  14. Training Preschool Children to Use Visual Imagining as a Problem-Solving Strategy for Complex Categorization Tasks

    ERIC Educational Resources Information Center

    Kisamore, April N.; Carr, James E.; LeBlanc, Linda A.

    2011-01-01

    It has been suggested that verbally sophisticated individuals engage in a series of precurrent behaviors (e.g., covert intraverbal behavior, grouping stimuli, visual imagining) to solve problems such as answering questions (Palmer, 1991; Skinner, 1953). We examined the effects of one problem solving strategy--visual imagining--on increasing…

  15. Evaluation of spectral light management on growth of container-grown willow oak, nuttall oak and summer red maple

    USDA-ARS?s Scientific Manuscript database

    Plant response to blue, red, gray or black shade cloth was evaluated with willow oak (Quercus phellos L.), Nuttall oak (Quercus nuttallii Palmer, Nuttall) and Summer Red maple (Acer rubrum L. ‘Summer Red’) liners. Light transmitted through the colored shade cloth had no influence on germination of ...

  16. Effects of Seedbed Density and Row Spacing on Growth and Nutrient Concentrations of Nuttall Oak and Green Ash Seedlings

    Treesearch

    Harvey E. Kennedy

    1988-01-01

    Larger size and higher percentages of plantable 1-0 and 2-0 green ash (Fraxinus pennsylvanica Marsh.) and Nuttall oak (Quercus nuttallii Palmer) seedlings were produced in the wider spacing-lower density plots. Greater numbers of plantable seedlings were produced in the higher density plots. Spacing significantly affected...

  17. Exploiting Formation Flying for Fuel Saving Supersonic Oblique Wing Aircraft

    DTIC Science & Technology

    2007-07-01

    used and developed during recent wing / winglet / morphing design programmes (Refs.13-14). By exploiting this method, we have assessed the aerodynamics...with winglets ”, AIAA-2006-3460. 25th Applied Aero Conference, San Francisco, June 2006. 15. NANGIA, R.K., PALMER, M.E., “Formation Flying of Commercial

  18. The Contours of Inclusion: Frameworks and Tools for Evaluating Arts in Education

    ERIC Educational Resources Information Center

    Glass, Don; Palmer Wolf, Dennie; Molloy, Traci; Rodriguez, Aamir; Horowitz, Robert; Burnaford, Gail; Mertens, Donna M.

    2008-01-01

    This collection of essays explores various arts education-specific evaluation tools, as well as considers Universal Design for Learning (UDL) and the inclusion of people with disabilities in the design of evaluation instruments and strategies. Prominent evaluators Donna M. Mertens, Robert Horowitz, Dennie Palmer Wolf, and Gail Burnaford are…

  19. 77 FR 51724 - Airworthiness Directives; The Boeing Company

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-27

    ... ON Thrust Levers CLOSE Speed Brakes FLIGHT DETENT Target Speed MO/MMO'' Note 1 to paragraphs (j)(2... W. Palmer, Aerospace Engineer, Systems and Equipment Branch, ANM-130S, FAA, Seattle Aircraft... charges the FAA with promoting safe flight of civil aircraft in air commerce by prescribing regulations...

  20. Higher Education Exchange 1996.

    ERIC Educational Resources Information Center

    Brown, David W., Ed.

    Nine articles discuss the nature and structure of public scholarship. The articles are: (1) "Divided No More" by Parker J. Palmer, who urges academics to act publicly on their convictions; (2) "The Public Intellectual as Transgressor?" by William M. Sullivan, who urges the reinvention of a "public" orientation to…

  1. The relationship between color-object associations and color preference: further investigation of ecological valence theory.

    PubMed

    Taylor, Chloe; Franklin, Anna

    2012-04-01

    Ecological valence theory (EVT; Palmer & Schloss, Proceedings of the National Academy of Sciences 107:8877-8882, 2010) proposes that color preferences are due to affective responses to color-associated objects: That is, people generally like colors to the degree that they like the objects associated with those colors. Palmer and Schloss found that the average valence of objects associated with a color, when weighted by how well the objects matched the color (weighted affective valence estimates: WAVE) explained 80% of the variation in preference across colors. Here, we replicated and extended Palmer and Schloss's investigation to establish whether color-object associations can account for sex differences in color preference and whether the relationship between associated objects and color preference is equally strong for males and females. We found some degree of sex specificity to the WAVEs, but the relationship between WAVE and color preference was significantly stronger for males than for females (74% shared variance for males, 45% for females). Furthermore, analyses identified a significant inverse relationship between the number of objects associated with a color and preference for the color. Participants generally liked colors associated with few objects and disliked colors associated with many objects. For the sample overall and for females alone, this association was not significantly weaker than the association of the WAVE and preference. The success of the WAVE at capturing color preference was partly due to the relationship between the number of associated objects and color preference. The findings identify constraints of EVT in its current form, but they also provide general support for the link between color preference and color-object associations.

  2. NSU Emergency Advisory Information

    Science.gov Websites

    Mailman Segal Center for Human Development Ron and Kathy Assaf College of Nursing Shepard Broad College of . Continuing Education Financial Aid Career Development Regional Campuses International Affairs Veterans Arts and culture on campus including theatre, music, and art. Campus Housing Off-Campus Housing Campus

  3. NSU Undergraduate Student Tuition and Fees

    Science.gov Websites

    Mailman Segal Center for Human Development Ron and Kathy Assaf College of Nursing Shepard Broad College of . Continuing Education Financial Aid Career Development Regional Campuses International Affairs Veterans Arts and culture on campus including theatre, music, and art. Campus Housing Off-Campus Housing Campus

  4. Nova Southeastern University (NSU) Guy Harvey Oceanographic Center

    Science.gov Websites

    Mailman Segal Center for Human Development Ron and Kathy Assaf College of Nursing Shepard Broad College of . Continuing Education Financial Aid Career Development Regional Campuses International Affairs Veterans Arts and culture on campus including theatre, music, and art. Campus Housing Off-Campus Housing Campus

  5. Employment & Careers | Nova Southeastern Universtiy

    Science.gov Websites

    Mailman Segal Center for Human Development Ron and Kathy Assaf College of Nursing Shepard Broad College of . Continuing Education Financial Aid Career Development Regional Campuses International Affairs Veterans Arts and culture on campus including theatre, music, and art. Campus Housing Off-Campus Housing Campus

  6. Expedition 27 and Expedition 28 crew members NBL training

    NASA Image and Video Library

    2010-10-26

    PHOTO DATE: 10-26-10 LOCATION: NBL - Pool Topside SUBJECT: Expedition 27 crew member Ron Garan and Expedition 28 crew member Mike Fossum during a joint INC-27/INC-28 ISS EVA Cleanup training session at the NBL WORK ORDER: 03126-BS__NBLEXP27_10-26-10 PHOTOGRAPHER: BILL STAFFORD

  7. Relational Inquiries and the Research Interview: Mentoring Future Researchers

    ERIC Educational Resources Information Center

    Hoskins, Marie L.; White, Jennifer

    2013-01-01

    In this article we describe some of the challenges and constraints that students face when they engage in qualitative research interviews. We borrow extensively from Ron Pelias' in-depth description of "leaning in" during everyday life encounters. Although he refers to other kinds of relationships, we believe that the similarities…

  8. TESL Reporter, Vol. 10, No. 2, Winter 1977.

    ERIC Educational Resources Information Center

    Pack, Alice C., Ed.

    This newsletter contains five articles. The first, "Discourse Structure in Reading," by Ron Shook, suggests that reading materials for the beginning ESL (English as a second language) reader often have three defects: (1) profusion of detail as question fodder; (2) an oversimplified syntax; and (3) an artificial construction that violates…

  9. Lifelong Learning.

    ERIC Educational Resources Information Center

    Learning Quarterly, 1998

    1998-01-01

    The theme of this issue is lifelong learning. Contents include a message introducing the publisher's Chief Executive Officer, Devron Gaber, and letters to the editor. A guest editorial, "Lifelong Learning For All: A National, Social, Corporate, and Personal Imperative for the Knowledge-Based 21st Century" (Ron Faris), considers how…

  10. Television Studies: A Widening Perspective.

    ERIC Educational Resources Information Center

    Comstock, George

    1981-01-01

    Reviews three books concerned with the effects of television advertising upon children and their parents: "Television Advertising and Children," edited by June Esserman; "Children and the Faces of Television," edited by Edward Palmer and Aimee Dorr; and "The Effects of Television Advertising on Children," by Richard Adler and others. (JJD)

  11. Performance of nuttall oak (Quercus Texana Buckl.) provenances in the Western Gulf Region

    Treesearch

    D.P. Gwaze; T.D. Byram; E.M. Raley

    2003-01-01

    Three series of three tests each of Nuttall oak (Quercus texana Buckl. formally Q. nuttallii Palmer) were established by the Western Gulf Forest Tree Improvement Program at three locations: Desha and Lonoke Counties in Arkansas and Sharkey County in Mississippi. The three series included 28-42 different half-sib families from...

  12. Making Class Size Work in the Middle Grades

    ERIC Educational Resources Information Center

    Tienken, C. H.; Achilles, C. M.

    2006-01-01

    Most research on the positive effects of class-size reduction (CSR) has occurred in the elementary level (Word, Johnston, Bain, Fulton, Zaharias, Lintz, Achilles, Folger, & Breda, 1990; Molnar, Smith, Zahorik, Palmer, Halbach, & Ehrle, 1999). Is CSR an important variable in improving education in the middle grades? Can small classes be…

  13. Geopolitics and "The Courage to Teach": Identity, Integrity and the Subject of Political Geography

    ERIC Educational Resources Information Center

    Flint, Colin

    2002-01-01

    Previous literature discussing and exemplifying the teaching of political geography has emphasized the material to be disseminated. Building upon those contributions, this paper offers a means of connecting student, teacher, and subject matter. Using the perspective of Parker Palmer, as illustrated in his book "The Courage to Teach," it is…

  14. "Blessed Are the Poor in Spirit": Imagining Excellence Otherwise

    ERIC Educational Resources Information Center

    Bowen, Deborah C.

    2010-01-01

    Jesus's blessing of the "poor in spirit," who recognize their dependence on God, suggests that an awareness of human limitation is necessary for wise living. How can the Christian educator teach for spiritual poverty? Both Parker Palmer and Richard Kearney, from their different disciplinary and denominational perspectives, argue for the central…

  15. 78 FR 48885 - Changes in Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-12

    ...- August 12, 2013...... 420713 Whitpain (12-03- Joseph J. Palmer, Building, 960 team.com/lomrs.htm. 1849P... team.com/lomrs.htm. City of Sachse, Department, 5560 3815 Sachse Road, Highway 78, Building B, Sachse... flood insurance premium rates for new buildings and the contents of those buildings. For rating purposes...

  16. Severity Levels and Symptoms Complexes for Acute Radiation Sickness -- Description and Quantification

    DTIC Science & Technology

    1985-11-30

    of military task performance levels. This effort was performed under the guidance and direction of DNA staff members Dr. David Auton and Dr. Robert W...INC ATTN: J HOWE ATTN: S SHRIER HORIZONS TECHNOLOGY, INC S-CUBEDATTN: B PYATT ATTN: J PALMER I:T RESEARCH INSTITUTE SCIENCE APPLICATIONS INTL CORP

  17. Characters and Episodes that Provide Models for Middle School Writers

    ERIC Educational Resources Information Center

    Pelttari, Carole

    2012-01-01

    While conducting a content analysis of award-winning, middle school fiction, I indentified a number of episodes and characters that might be used as models for students' writing. Research suggests that teachers can motivate students (Bruning & Horn, 2000; Codling, Gambrell, Kennedy, Palmer, & Graham, 1996) to respond to character-writers (Van…

  18. It's Not Polite to Interrupt, and Other Rules of Classroom Etiquette

    ERIC Educational Resources Information Center

    Croom, Loren; Davis, Barbara H.

    2006-01-01

    Numerous classroom-based research projects have examined the important role social skills play in an elementary classroom (Browning, Davis, and Resta 2000; Burns 2003; Palmer and Wehmeyer 2003; Stone 2001). As Stone (2001, 18) suggested, "Teachers have an enormous influence on children's behavior by speaking directly and honestly to them,…

  19. ARC-2011-ACD11-0012-012

    NASA Image and Video Library

    2011-01-26

    Technology Partnerships awards: Federal Laboratory Consortium Far West Region Award for Outstanding Technology Development for Multi-Aircraft Control System. In particular order are Connie Brasil, Todd Callantine, Al Globus, Jeff Homola, Rich Jacoby, George Lawton, Paul Lee, Matt Mainini, Joey Mercer, Ev Palmer, Tom Prevot, Nancy Smith, Easter Wang, James Wong.

  20. Nuttall Oak Direct Seedings Still Successful After 11 Years

    Treesearch

    Robert L. Johnson

    1983-01-01

    Forty-five hundred acorns of Nuttall oak (Quercus nuttallii Palmer) were either machine or manually sown at 2-, 4-, or 6-inch depths in a 20-acre, intensively site-prepared clearing within the Delta Experimental Forest located near Stoneville, Mississippi. Field germination averaged 36 percent; no significant differences in germination appeared...

  1. Bullying of LGBTQ Students: A Problem Recognized by Students, Parents, and Teachers

    ERIC Educational Resources Information Center

    Kolbert, Jered B.; Crothers, Laura M.; Meidl, Christopher; Berbary, Cassandra; Chatlos, Suzannah; Lattanzio, Latitia; Tiberi, Amy E.; Wells, Daniel S.; Wadsworth, Jacob

    2018-01-01

    Research reveals that students who identify as lesbian, gay, bisexual, transgender, and questioning (LGBTQ) often do not feel safe at school as a result of higher rates of bullying in comparison to their heterosexual peers (Kann et al., 2016; Kosciw, Greytak, Palmer, & Boesen, 2014; Russell, Clarke, & Lamb, 2009). Compared to general…

  2. 77 FR 75165 - Proposed Data Collections Submitted for Public Comment and Recommendations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-19

    ... on proposed data collection projects, the Centers for Disease Control and Prevention (CDC) will... Ron Otten, 1600 Clifton Road, MS-D74, Atlanta, GA 30333 or send an email to [email protected]cdc.gov . Comments are...), Centers for Disease Control and Prevention (CDC). Background and Brief Description The health burden of...

  3. 77 FR 50698 - Proposed Data Collections Submitted for Public Comment and Recommendations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-22

    ... (in hours respondent hours) State Health Departments...... Electronic STD 50 52 20/60 867 Case report. Territorial Health Agencies... Electronic STD 5 52 20/60 87 Case report. City and county health Electronic STD 2 52 20/60 35 departments. Case report. Totals 989 Dated: August 16, 2012. Ron A. Otten, Director...

  4. 75 FR 12745 - SFIREG Environmental Quality Issues Working Committee Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-17

    ..., beginning on April 26, 2010, and ending April 27, 2010. This notice announces the location and times for... CONTACT, preferably at least 10 days prior to the meeting, to give EPA as much time as possible to process... Crystal Dr., Arlington, VA., First Floor, South Conference Room. FOR FURTHER INFORMATION CONTACT: Ron...

  5. From Seatwork to Feetwork: Engaging Students in Their Own Learning

    ERIC Educational Resources Information Center

    Nash, Ron

    2011-01-01

    How do you teach students to communicate, collaborate, and solve problems? In his engaging style, Ron Nash shows teachers how to create a student-centered environment that transforms learners from passive attendees into active participants and leaders in the classroom. Building on the foundation of his prior works on active learning, he combines…

  6. A Scholarship Program where Students Give Back

    ERIC Educational Resources Information Center

    Masterson, Kathryn

    2009-01-01

    Alumni of the Ron Brown Scholar Program, young adults selected for their intellect, leadership skills, service, and financial need, are finding success in the law, government, science, business, medicine, and the arts. Yet they remain tied to the scholarship program, contributing to its continued success by donating money and volunteer hours to…

  7. The Impact of Advisor Outreach on Priority Registration

    ERIC Educational Resources Information Center

    McClure, Jennifer L.

    2017-01-01

    In 2015, Elgin Community College's Student Success Infrastructure used the book "Influencer: The New Science of Leading Change" (2013) by Joseph Grenny, Kerry Patterson, David Maxfield, Ron McMillan, and Al Switzler to help frame conversations about improving student success. One of the book's main concepts is using data to identify and…

  8. 77 FR 3756 - Nevada Irrigation District; Notice of Application Accepted for Filing, Soliciting Motions To...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-25

    ...: Federal Power Act 16 USC 791 (a)-825(r) . h. Applicant Contact: Ron Nelson, General Manager, Nevada Irrigation District, 1036 West Main Street, Grass Valley, CA 95945, (530) 271-6824 or email [email protected] Support. A copy is also available for inspection and reproduction at the address in item h above. Register...

  9. Developing Software to Use Parallel Processing Effectively

    DTIC Science & Technology

    1988-10-01

    Experience, Vol 15(6), June 1985, p53 Gajski85 Gajski , Daniel D. and Jih-Kwon Peir, "Essential Issues in Multiprocessor Systems", IEEE Computer, June...Treleaven (eds.), Springer-Verlag, pp. 213-225 (June 1987). Kuck83 David Kuck, Duncan Lawrie, Ron Cytron, Ahmed Sameh and Daniel Gajski , The Architecture and

  10. Community Attitudes about Economic Impacts of Colleges: A Case Study. AIR 1996 Annual Forum Paper.

    ERIC Educational Resources Information Center

    Stout, Robert J.

    This study examined attitudes of people about benefits of the economic impacts of two local colleges (Palmer College of Chiropractic and Scott Community College) in the metropolitan Quad Cities area of Rock Island County (Illinois) and Scott County (Iowa). The study compared impacts considered important by the community with those estimated by the…

  11. Delving into Key Dimensions of ESD through Analyses of a Middle School Science Textbook

    ERIC Educational Resources Information Center

    Sahin, Elvan

    2016-01-01

    Uncertainties and debates regarding the term of sustainable development are still going on, and similarly, the notion of education for sustainable development (ESD) is open to debate. There has been an attempt to make the concept of ESD evident, which is quite challenging. Palmer (1998) stated the appropriateness of ESD within environmental…

  12. Relationship between crown dieback and drought in the southeastern United States

    Treesearch

    Michael K. Crosby; Zhaofei Fan; Martin A. Spetich; Theodor D. Leininger; Xingang Fan

    2012-01-01

    Forest Health and Monitoring (FHM) and Palmer's Drought Severity Index (PDSI) data were obtained for 11 states in the southeastern United States to assess the relationship between drought and crown dieback. Correlation analyses were performed at the species group and ecoregion levels within the study area. The results indicate a negative correlation between...

  13. Selected Lexical Patterns in Saudi Arabian Sign Language

    ERIC Educational Resources Information Center

    Young, Lesa; Palmer, Jeffrey Levi; Reynolds, Wanette

    2012-01-01

    This combined paper will focus on the description of two selected lexical patterns in Saudi Arabian Sign Language (SASL): metaphor and metonymy in emotion-related signs (Young) and lexicalization patterns of objects and their derivational roots (Palmer and Reynolds). The over-arcing methodology used by both studies is detailed in Stephen and…

  14. Offering Reflection to an Organization

    ERIC Educational Resources Information Center

    Faulkner, Ann; Gooding, Guy

    2010-01-01

    From 1998 to 2008, the Dallas County Community College District (DCCCD) offered its employees a variety of options for formation, a type of reflective practice. The district encompasses 10 locations, seven of them independently accredited colleges. Formation is based primarily on Parker Palmer's model for Circles of Trust as described in "A…

  15. Time to Let Go of the Illusion that Psychotherapy Extends the Survival of Cancer Patients: Reply to Kraemer, Kuchler, and Spiegel (2009)

    ERIC Educational Resources Information Center

    Coyne, James C.; Thombs, Brett D.; Stefanek, Michael; Palmer, Steven C.

    2009-01-01

    Replies to comments from Kraemer, Kuchler, and Spiegel on the authors original article Psychotherapy and survival in cancer: The conflict between hope and evidence. The authors recently reviewed evidence related to the notion that psychotherapy extends survival in cancer patients (J. C. Coyne, M. Stefanek, & S. C. Palmer, 2007). The authors found…

  16. Early Malnutrition and Central Nervous System Function

    ERIC Educational Resources Information Center

    Scrimshaw, Nevin S.

    1969-01-01

    Discusses the consequences of severe malnutrition in young experimental animals. Development of the brain is permanently impaired. Studies of the effects of malnutrition on children are included. (This paper was presented at the Eighth Annual Lecture of the Merrill-Palmer Historical Library in Child Development and Family Life, October 25, 1968.)…

  17. Exploring the Power of Solo, Silence, and Solitude

    ERIC Educational Resources Information Center

    Knapp, Clifford E., Ed.; Smith, Thomas E., Ed.

    2005-01-01

    What do solitude experiences offer in this increasingly high-speed, technically dependent world? As this book inspiringly reveals, solo quests can provide powerful reconnection with the natural world, the true self, and the great mystery beyond. As Parker Palmer writes in "To Know as We Are Known," "Solitude calls us to confront…

  18. Pedagogy and the Teacher within: Reflections on Thoreau and Kinesiology in Higher Education

    ERIC Educational Resources Information Center

    Hochstetler, Douglas

    2013-01-01

    In his essay, "The Heart of a Teacher," educator Parker Palmer (1997b) examines the themes of identity and community which intersect with similar strains in American philosophy, most notably the transcendentalism of Henry David Thoreau. In this article, I argue that transcendental themes help provide insight into these pedagogical issues of…

  19. Survival and Growth of Individual Trees in Mixed-species Plantations of Bottomland Hardwoods on 2 Mississippi Delta Soil Types

    Treesearch

    Jefferey C. Goelz

    2001-01-01

    Water oak (Quercus nigra L.[Fagaceae]), Nuttall oak (Q. nuttallii Palmer), and green ash (Fraxinus pennsylvanica Marsh. [Oleaceae]) were planted in mixtures at 2 spacings, 1.8 and 2.7m (6 and 9 ft) triangular spacing, on 2 contrasting soil types: Sharkey and Dundee. Survival was high for green ash and...

  20. Road Tripping down the Digital Preservation Highway, Part I: Hitting the Road

    ERIC Educational Resources Information Center

    Colati, Jessica Branco; Colati, Gregory C.

    2011-01-01

    In this inaugural column, the authors introduce Peter Palmer, erstwhile librarian at Bellaluna University who is being tasked with managing the library's and university's digital content as he begins his journey down the Digital Highway. As head of access services at Bellaluna University, Peter had been, by default, made responsible for managing…